Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= brP-1708
(700 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
M90299-1|AAA52562.1| 465|Homo sapiens glucokinase protein. 126 6e-29
M88011-1|AAA51824.1| 465|Homo sapiens glucokinase protein. 126 6e-29
EU008605-1|ABS31137.1| 465|Homo sapiens glucokinase protein. 126 6e-29
BT007062-1|AAP35711.1| 465|Homo sapiens glucokinase (hexokinase... 126 6e-29
BC001890-1|AAH01890.1| 465|Homo sapiens glucokinase (hexokinase... 126 6e-29
AF041022-1|AAB97680.1| 465|Homo sapiens glucokinase protein. 126 6e-29
U51333-1|AAC50732.1| 923|Homo sapiens hexokinase III protein. 125 2e-28
BC028129-1|AAH28129.1| 923|Homo sapiens hexokinase 3 (white cel... 125 2e-28
AB208951-1|BAD92188.1| 960|Homo sapiens Hexokinase 3 variant pr... 125 2e-28
M69051-1|AAB59563.1| 464|Homo sapiens glucokinase protein. 124 4e-28
AF041022-3|AAB97682.1| 464|Homo sapiens glucokinase protein. 124 4e-28
AF041022-2|AAB97681.1| 466|Homo sapiens glucokinase protein. 123 5e-28
BC110505-1|AAI10506.2| 917|Homo sapiens hexokinase domain conta... 122 1e-27
BC110504-1|AAI10505.1| 917|Homo sapiens hexokinase domain conta... 122 1e-27
BC012337-1|AAH12337.1| 677|Homo sapiens HKDC1 protein protein. 122 1e-27
AL596223-3|CAH71500.1| 917|Homo sapiens hexokinase domain conta... 122 1e-27
AK026414-1|BAB15478.1| 325|Homo sapiens protein ( Homo sapiens ... 122 1e-27
Z46376-1|CAA86511.1| 917|Homo sapiens Human hexokinase II cDNA ... 121 2e-27
BC064369-1|AAH64369.1| 917|Homo sapiens hexokinase 2 protein. 121 2e-27
BC021116-1|AAH21116.1| 917|Homo sapiens hexokinase 2 protein. 121 2e-27
AY623118-1|AAT38114.1| 917|Homo sapiens hexokinase 2 protein. 121 2e-27
AF148513-1|AAD30174.1| 917|Homo sapiens hexokinase II protein. 121 2e-27
AC019069-1|AAX93084.1| 344|Homo sapiens unknown protein. 121 2e-27
Z46354-1|CAA86476.2| 916|Homo sapiens hexokinase II protein. 121 3e-27
X66957-1|CAA47379.1| 631|Homo sapiens hexokinase type 1 protein. 120 4e-27
M75126-1|AAA52646.1| 917|Homo sapiens hexokinase 1 protein. 120 4e-27
BC008730-1|AAH08730.1| 917|Homo sapiens hexokinase 1 protein. 120 4e-27
AL596223-9|CAH71506.1| 917|Homo sapiens hexokinase 1 protein. 120 4e-27
AF016365-4|AAC15862.1| 917|Homo sapiens hexokinase I protein. 120 4e-27
AF016365-3|AAC15863.1| 916|Homo sapiens hexokinase IR protein. 120 4e-27
AF016365-2|AAF82320.1| 905|Homo sapiens hexokinase 1 isoform td... 120 4e-27
AF016365-1|AAF82319.1| 921|Homo sapiens hexokinase 1 isoform ta... 120 4e-27
AB209526-1|BAD92763.1| 949|Homo sapiens hexokinase 1 isoform HK... 120 4e-27
BC021278-1|AAH21278.1| 427|Homo sapiens HKDC1 protein protein. 118 2e-26
AC104135-1|AAY24209.1| 573|Homo sapiens unknown protein. 115 1e-25
U42303-1|AAC50422.1| 566|Homo sapiens ATP:D-hexose 6-phosphotra... 108 2e-23
AL596223-8|CAH71505.1| 291|Homo sapiens hexokinase 1 protein. 108 2e-23
AL596223-5|CAH71502.1| 139|Homo sapiens hexokinase 1 protein. 65 3e-10
AL596223-7|CAH71504.1| 114|Homo sapiens hexokinase 1 protein. 55 3e-07
AF073786-1|AAC25424.1| 114|Homo sapiens testis-specific hexokin... 55 3e-07
DQ871602-1|ABI49509.1| 127|Homo sapiens HK2 protein. 42 0.002
D25412-1|BAA04999.1| 126|Homo sapiens type 2 hexokinase protein. 36 0.18
BX538078-1|CAD98002.1| 160|Homo sapiens hypothetical protein pr... 33 0.74
M34338-1|AAA36633.1| 302|Homo sapiens spermidine synthase protein. 30 6.9
M64231-1|AAA60574.1| 302|Homo sapiens spermidine synthase protein. 30 9.1
BC033106-1|AAH33106.1| 302|Homo sapiens spermidine synthase pro... 30 9.1
BC000309-1|AAH00309.1| 302|Homo sapiens spermidine synthase pro... 30 9.1
AL109811-6|CAI22104.1| 302|Homo sapiens spermidine synthase pro... 30 9.1
>M90299-1|AAA52562.1| 465|Homo sapiens glucokinase protein.
Length = 465
Score = 126 bits (305), Expect = 6e-29
Identities = 65/167 (38%), Positives = 99/167 (59%), Gaps = 7/167 (4%)
Frame = +3
Query: 12 RAQKIEARLSKLMLCGSTLRRVAEVFEKEIEAGLR---QQPSSLQMENTYVPELPDGTEE 182
+ +K+E L++ L L++V +KE++ GLR + +S++M TYV P+G+E
Sbjct: 12 KKEKVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEV 71
Query: 183 GSFLALDLGGTNFRVLFLELKAGQ--LLREKVKH--YHINDALRLGPGEDLFNFLADCVQ 350
G FL+LDLGGTNFRV+ +++ G+ K KH Y I + G E LF+++++C+
Sbjct: 72 GDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECIS 131
Query: 351 DFLVSQSMEKETFSLGFTFSFPMRQHSISSGELITWTKSFNCGGMDG 491
DFL M+ + LGFTFSFP+R I G L+ WTK F G +G
Sbjct: 132 DFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEG 178
Score = 32.3 bits (70), Expect = 1.7
Identities = 23/76 (30%), Positives = 37/76 (48%), Gaps = 1/76 (1%)
Frame = +1
Query: 439 LEN*SLGRRASTAAEWTGFDVAALLQRCLSARS-LDVTVRVLLNDTTGTLVAGAHIDRNV 615
L N + G +AS A G +V LL+ + R ++ V ++NDT T+++ + D
Sbjct: 164 LLNWTKGFKASGAE---GNNVVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDHQC 220
Query: 616 GIXXDSGYRLNRCYME 663
+ G N CYME
Sbjct: 221 EVGMIVGTGCNACYME 236
>M88011-1|AAA51824.1| 465|Homo sapiens glucokinase protein.
Length = 465
Score = 126 bits (305), Expect = 6e-29
Identities = 65/167 (38%), Positives = 99/167 (59%), Gaps = 7/167 (4%)
Frame = +3
Query: 12 RAQKIEARLSKLMLCGSTLRRVAEVFEKEIEAGLR---QQPSSLQMENTYVPELPDGTEE 182
+ +K+E L++ L L++V +KE++ GLR + +S++M TYV P+G+E
Sbjct: 12 KKEKVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEV 71
Query: 183 GSFLALDLGGTNFRVLFLELKAGQ--LLREKVKH--YHINDALRLGPGEDLFNFLADCVQ 350
G FL+LDLGGTNFRV+ +++ G+ K KH Y I + G E LF+++++C+
Sbjct: 72 GDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECIS 131
Query: 351 DFLVSQSMEKETFSLGFTFSFPMRQHSISSGELITWTKSFNCGGMDG 491
DFL M+ + LGFTFSFP+R I G L+ WTK F G +G
Sbjct: 132 DFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEG 178
Score = 32.3 bits (70), Expect = 1.7
Identities = 23/76 (30%), Positives = 37/76 (48%), Gaps = 1/76 (1%)
Frame = +1
Query: 439 LEN*SLGRRASTAAEWTGFDVAALLQRCLSARS-LDVTVRVLLNDTTGTLVAGAHIDRNV 615
L N + G +AS A G +V LL+ + R ++ V ++NDT T+++ + D
Sbjct: 164 LLNWTKGFKASGAE---GNNVVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDHQC 220
Query: 616 GIXXDSGYRLNRCYME 663
+ G N CYME
Sbjct: 221 EVGMIVGTGCNACYME 236
>EU008605-1|ABS31137.1| 465|Homo sapiens glucokinase protein.
Length = 465
Score = 126 bits (305), Expect = 6e-29
Identities = 65/167 (38%), Positives = 99/167 (59%), Gaps = 7/167 (4%)
Frame = +3
Query: 12 RAQKIEARLSKLMLCGSTLRRVAEVFEKEIEAGLR---QQPSSLQMENTYVPELPDGTEE 182
+ +K+E L++ L L++V +KE++ GLR + +S++M TYV P+G+E
Sbjct: 12 KKEKVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEV 71
Query: 183 GSFLALDLGGTNFRVLFLELKAGQ--LLREKVKH--YHINDALRLGPGEDLFNFLADCVQ 350
G FL+LDLGGTNFRV+ +++ G+ K KH Y I + G E LF+++++C+
Sbjct: 72 GDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECIS 131
Query: 351 DFLVSQSMEKETFSLGFTFSFPMRQHSISSGELITWTKSFNCGGMDG 491
DFL M+ + LGFTFSFP+R I G L+ WTK F G +G
Sbjct: 132 DFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEG 178
Score = 32.3 bits (70), Expect = 1.7
Identities = 23/76 (30%), Positives = 37/76 (48%), Gaps = 1/76 (1%)
Frame = +1
Query: 439 LEN*SLGRRASTAAEWTGFDVAALLQRCLSARS-LDVTVRVLLNDTTGTLVAGAHIDRNV 615
L N + G +AS A G +V LL+ + R ++ V ++NDT T+++ + D
Sbjct: 164 LLNWTKGFKASGAE---GNNVVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDHQC 220
Query: 616 GIXXDSGYRLNRCYME 663
+ G N CYME
Sbjct: 221 EVGMIVGTGCNACYME 236
>BT007062-1|AAP35711.1| 465|Homo sapiens glucokinase (hexokinase 4,
maturity onset diabetes of the young 2) protein.
Length = 465
Score = 126 bits (305), Expect = 6e-29
Identities = 65/167 (38%), Positives = 99/167 (59%), Gaps = 7/167 (4%)
Frame = +3
Query: 12 RAQKIEARLSKLMLCGSTLRRVAEVFEKEIEAGLR---QQPSSLQMENTYVPELPDGTEE 182
+ +K+E L++ L L++V +KE++ GLR + +S++M TYV P+G+E
Sbjct: 12 KKEKVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEV 71
Query: 183 GSFLALDLGGTNFRVLFLELKAGQ--LLREKVKH--YHINDALRLGPGEDLFNFLADCVQ 350
G FL+LDLGGTNFRV+ +++ G+ K KH Y I + G E LF+++++C+
Sbjct: 72 GDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECIS 131
Query: 351 DFLVSQSMEKETFSLGFTFSFPMRQHSISSGELITWTKSFNCGGMDG 491
DFL M+ + LGFTFSFP+R I G L+ WTK F G +G
Sbjct: 132 DFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEG 178
Score = 32.3 bits (70), Expect = 1.7
Identities = 23/76 (30%), Positives = 37/76 (48%), Gaps = 1/76 (1%)
Frame = +1
Query: 439 LEN*SLGRRASTAAEWTGFDVAALLQRCLSARS-LDVTVRVLLNDTTGTLVAGAHIDRNV 615
L N + G +AS A G +V LL+ + R ++ V ++NDT T+++ + D
Sbjct: 164 LLNWTKGFKASGAE---GNNVVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDHQC 220
Query: 616 GIXXDSGYRLNRCYME 663
+ G N CYME
Sbjct: 221 EVGMIVGTGCNACYME 236
>BC001890-1|AAH01890.1| 465|Homo sapiens glucokinase (hexokinase 4,
maturity onset diabetes of the young 2) protein.
Length = 465
Score = 126 bits (305), Expect = 6e-29
Identities = 65/167 (38%), Positives = 99/167 (59%), Gaps = 7/167 (4%)
Frame = +3
Query: 12 RAQKIEARLSKLMLCGSTLRRVAEVFEKEIEAGLR---QQPSSLQMENTYVPELPDGTEE 182
+ +K+E L++ L L++V +KE++ GLR + +S++M TYV P+G+E
Sbjct: 12 KKEKVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEV 71
Query: 183 GSFLALDLGGTNFRVLFLELKAGQ--LLREKVKH--YHINDALRLGPGEDLFNFLADCVQ 350
G FL+LDLGGTNFRV+ +++ G+ K KH Y I + G E LF+++++C+
Sbjct: 72 GDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECIS 131
Query: 351 DFLVSQSMEKETFSLGFTFSFPMRQHSISSGELITWTKSFNCGGMDG 491
DFL M+ + LGFTFSFP+R I G L+ WTK F G +G
Sbjct: 132 DFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEG 178
Score = 32.3 bits (70), Expect = 1.7
Identities = 23/76 (30%), Positives = 37/76 (48%), Gaps = 1/76 (1%)
Frame = +1
Query: 439 LEN*SLGRRASTAAEWTGFDVAALLQRCLSARS-LDVTVRVLLNDTTGTLVAGAHIDRNV 615
L N + G +AS A G +V LL+ + R ++ V ++NDT T+++ + D
Sbjct: 164 LLNWTKGFKASGAE---GNNVVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDHQC 220
Query: 616 GIXXDSGYRLNRCYME 663
+ G N CYME
Sbjct: 221 EVGMIVGTGCNACYME 236
>AF041022-1|AAB97680.1| 465|Homo sapiens glucokinase protein.
Length = 465
Score = 126 bits (305), Expect = 6e-29
Identities = 65/167 (38%), Positives = 99/167 (59%), Gaps = 7/167 (4%)
Frame = +3
Query: 12 RAQKIEARLSKLMLCGSTLRRVAEVFEKEIEAGLR---QQPSSLQMENTYVPELPDGTEE 182
+ +K+E L++ L L++V +KE++ GLR + +S++M TYV P+G+E
Sbjct: 12 KKEKVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEV 71
Query: 183 GSFLALDLGGTNFRVLFLELKAGQ--LLREKVKH--YHINDALRLGPGEDLFNFLADCVQ 350
G FL+LDLGGTNFRV+ +++ G+ K KH Y I + G E LF+++++C+
Sbjct: 72 GDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECIS 131
Query: 351 DFLVSQSMEKETFSLGFTFSFPMRQHSISSGELITWTKSFNCGGMDG 491
DFL M+ + LGFTFSFP+R I G L+ WTK F G +G
Sbjct: 132 DFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEG 178
Score = 32.3 bits (70), Expect = 1.7
Identities = 23/76 (30%), Positives = 37/76 (48%), Gaps = 1/76 (1%)
Frame = +1
Query: 439 LEN*SLGRRASTAAEWTGFDVAALLQRCLSARS-LDVTVRVLLNDTTGTLVAGAHIDRNV 615
L N + G +AS A G +V LL+ + R ++ V ++NDT T+++ + D
Sbjct: 164 LLNWTKGFKASGAE---GNNVVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDHQC 220
Query: 616 GIXXDSGYRLNRCYME 663
+ G N CYME
Sbjct: 221 EVGMIVGTGCNACYME 236
>U51333-1|AAC50732.1| 923|Homo sapiens hexokinase III protein.
Length = 923
Score = 125 bits (301), Expect = 2e-28
Identities = 66/164 (40%), Positives = 91/164 (55%), Gaps = 2/164 (1%)
Frame = +3
Query: 6 RLRAQK--IEARLSKLMLCGSTLRRVAEVFEKEIEAGLRQQPSSLQMENTYVPELPDGTE 179
RL A + +E L+ L L V K + GLR + SSL+M T+V PDG+E
Sbjct: 475 RLAAHRRLLEETLAPFRLNHDQLAAVQAQMRKAMAKGLRGEASSLRMLPTFVRATPDGSE 534
Query: 180 EGSFLALDLGGTNFRVLFLELKAGQLLREKVKHYHINDALRLGPGEDLFNFLADCVQDFL 359
G FLALDLGGTNFRVL + + G + ++ Y I + + G G+ LF+ + DC+ DF
Sbjct: 535 RGDFLALDLGGTNFRVLLVRVTTGVQITSEI--YSIPETVAQGSGQQLFDHIVDCIVDFQ 592
Query: 360 VSQSMEKETFSLGFTFSFPMRQHSISSGELITWTKSFNCGGMDG 491
Q + ++ LGFTFSFP RQ + G L+ WTK F +G
Sbjct: 593 QKQGLSGQSLPLGFTFSFPCRQLGLDQGILLNWTKGFKASDCEG 636
Score = 104 bits (250), Expect = 3e-22
Identities = 56/166 (33%), Positives = 93/166 (56%), Gaps = 7/166 (4%)
Frame = +3
Query: 15 AQKIEARLSKLMLCGSTLRRVAEVFEKEIEAGLRQQPS---SLQMENTYVPELPDGTEEG 185
++ ++ L + + + L+++ +E LR Q S +++M TYV P GTE+G
Sbjct: 30 SELVQECLQQFKVTRAQLQQIQASLLGSMEQALRGQASPAPAVRMLPTYVGSTPHGTEQG 89
Query: 186 SFLALDLG--GTNFRVLFLELKA--GQLLREKVKHYHINDALRLGPGEDLFNFLADCVQD 353
F+ L+LG G + RVL++ L G + + + + I + LG G+ LF+F A C+ +
Sbjct: 90 DFVVLELGATGASLRVLWVTLTGIEGHRVEPRSQEFVIPQEVMLGAGQQLFDFAAHCLSE 149
Query: 354 FLVSQSMEKETFSLGFTFSFPMRQHSISSGELITWTKSFNCGGMDG 491
FL +Q + K+ LGF+FSFP Q + LI+WTK F C G++G
Sbjct: 150 FLDAQPVNKQGLQLGFSFSFPCHQTGLDRSTLISWTKGFRCSGVEG 195
Score = 40.3 bits (90), Expect = 0.006
Identities = 21/64 (32%), Positives = 37/64 (57%), Gaps = 1/64 (1%)
Frame = +1
Query: 475 AAEWTGFDVAALLQRCLSAR-SLDVTVRVLLNDTTGTLVAGAHIDRNVGIXXDSGYRLNR 651
A++ G DV +LL+ ++ R ++++ V ++NDT GT+++ + D I G N
Sbjct: 631 ASDCEGQDVVSLLREAITRRQAVELNVVAIVNDTVGTMMSCGYEDPRCEIGLIVGTGTNA 690
Query: 652 CYME 663
CYME
Sbjct: 691 CYME 694
>BC028129-1|AAH28129.1| 923|Homo sapiens hexokinase 3 (white cell)
protein.
Length = 923
Score = 125 bits (301), Expect = 2e-28
Identities = 66/164 (40%), Positives = 91/164 (55%), Gaps = 2/164 (1%)
Frame = +3
Query: 6 RLRAQK--IEARLSKLMLCGSTLRRVAEVFEKEIEAGLRQQPSSLQMENTYVPELPDGTE 179
RL A + +E L+ L L V K + GLR + SSL+M T+V PDG+E
Sbjct: 475 RLAAHRRLLEETLAPFRLNHDQLAAVQAQMRKAMAKGLRGEASSLRMLPTFVRATPDGSE 534
Query: 180 EGSFLALDLGGTNFRVLFLELKAGQLLREKVKHYHINDALRLGPGEDLFNFLADCVQDFL 359
G FLALDLGGTNFRVL + + G + ++ Y I + + G G+ LF+ + DC+ DF
Sbjct: 535 RGDFLALDLGGTNFRVLLVRVTTGVQITSEI--YSIPETVAQGSGQQLFDHIVDCIVDFQ 592
Query: 360 VSQSMEKETFSLGFTFSFPMRQHSISSGELITWTKSFNCGGMDG 491
Q + ++ LGFTFSFP RQ + G L+ WTK F +G
Sbjct: 593 QKQGLSGQSLPLGFTFSFPCRQLGLDQGILLNWTKGFKASDCEG 636
Score = 104 bits (250), Expect = 3e-22
Identities = 56/166 (33%), Positives = 93/166 (56%), Gaps = 7/166 (4%)
Frame = +3
Query: 15 AQKIEARLSKLMLCGSTLRRVAEVFEKEIEAGLRQQPS---SLQMENTYVPELPDGTEEG 185
++ ++ L + + + L+++ +E LR Q S +++M TYV P GTE+G
Sbjct: 30 SELVQECLQQFKVTRAQLQQIQASLLGSMEQALRGQASPAPAVRMLPTYVGSTPHGTEQG 89
Query: 186 SFLALDLG--GTNFRVLFLELKA--GQLLREKVKHYHINDALRLGPGEDLFNFLADCVQD 353
F+ L+LG G + RVL++ L G + + + + I + LG G+ LF+F A C+ +
Sbjct: 90 DFVVLELGATGASLRVLWVTLTGIEGHRVEPRSQEFVIPQEVMLGAGQQLFDFAAHCLSE 149
Query: 354 FLVSQSMEKETFSLGFTFSFPMRQHSISSGELITWTKSFNCGGMDG 491
FL +Q + K+ LGF+FSFP Q + LI+WTK F C G++G
Sbjct: 150 FLDAQPVNKQGLQLGFSFSFPCHQTGLDRSTLISWTKGFRCSGVEG 195
Score = 40.3 bits (90), Expect = 0.006
Identities = 21/64 (32%), Positives = 37/64 (57%), Gaps = 1/64 (1%)
Frame = +1
Query: 475 AAEWTGFDVAALLQRCLSAR-SLDVTVRVLLNDTTGTLVAGAHIDRNVGIXXDSGYRLNR 651
A++ G DV +LL+ ++ R ++++ V ++NDT GT+++ + D I G N
Sbjct: 631 ASDCEGQDVVSLLREAITRRQAVELNVVAIVNDTVGTMMSCGYEDPRCEIGLIVGTGTNA 690
Query: 652 CYME 663
CYME
Sbjct: 691 CYME 694
>AB208951-1|BAD92188.1| 960|Homo sapiens Hexokinase 3 variant
protein.
Length = 960
Score = 125 bits (301), Expect = 2e-28
Identities = 66/164 (40%), Positives = 91/164 (55%), Gaps = 2/164 (1%)
Frame = +3
Query: 6 RLRAQK--IEARLSKLMLCGSTLRRVAEVFEKEIEAGLRQQPSSLQMENTYVPELPDGTE 179
RL A + +E L+ L L V K + GLR + SSL+M T+V PDG+E
Sbjct: 445 RLAAHRRLLEETLAPFRLNHDQLAAVQAQMRKAMAKGLRGEASSLRMLPTFVRATPDGSE 504
Query: 180 EGSFLALDLGGTNFRVLFLELKAGQLLREKVKHYHINDALRLGPGEDLFNFLADCVQDFL 359
G FLALDLGGTNFRVL + + G + ++ Y I + + G G+ LF+ + DC+ DF
Sbjct: 505 RGDFLALDLGGTNFRVLLVRVTTGVQITSEI--YSIPETVAQGSGQQLFDHIVDCIVDFQ 562
Query: 360 VSQSMEKETFSLGFTFSFPMRQHSISSGELITWTKSFNCGGMDG 491
Q + ++ LGFTFSFP RQ + G L+ WTK F +G
Sbjct: 563 QKQGLSGQSLPLGFTFSFPCRQLGLDQGILLNWTKGFKASDCEG 606
Score = 104 bits (250), Expect = 3e-22
Identities = 56/166 (33%), Positives = 93/166 (56%), Gaps = 7/166 (4%)
Frame = +3
Query: 15 AQKIEARLSKLMLCGSTLRRVAEVFEKEIEAGLRQQPS---SLQMENTYVPELPDGTEEG 185
++ ++ L + + + L+++ +E LR Q S +++M TYV P GTE+G
Sbjct: 42 SELVQECLQQFKVTRAQLQQIQASLLGSMEQALRGQASPAPAVRMLPTYVGSTPHGTEQG 101
Query: 186 SFLALDLG--GTNFRVLFLELKA--GQLLREKVKHYHINDALRLGPGEDLFNFLADCVQD 353
F+ L+LG G + RVL++ L G + + + + I + LG G+ LF+F A C+ +
Sbjct: 102 DFVVLELGATGASLRVLWVTLTGIEGHRVEPRSQEFVIPQEVMLGAGQQLFDFAAHCLSE 161
Query: 354 FLVSQSMEKETFSLGFTFSFPMRQHSISSGELITWTKSFNCGGMDG 491
FL +Q + K+ LGF+FSFP Q + LI+WTK F C G++G
Sbjct: 162 FLDAQPVNKQGLQLGFSFSFPCHQTGLDRSTLISWTKGFRCSGVEG 207
Score = 32.7 bits (71), Expect = 1.3
Identities = 22/73 (30%), Positives = 40/73 (54%), Gaps = 10/73 (13%)
Frame = +1
Query: 475 AAEWTGFDVAALLQRCLSAR-SLDVTVRVLLNDTTGTLVAGAHIDR--NVGIXXDS---- 633
A++ G DV +LL+ ++ R ++++ V ++NDT GT+++ + D +G+ S
Sbjct: 601 ASDCEGQDVVSLLREAITRRQAVELNVVAIVNDTVGTMMSCGYEDPRCEIGLIVASTLSG 660
Query: 634 ---GYRLNRCYME 663
G N CYME
Sbjct: 661 LSAGTGTNACYME 673
>M69051-1|AAB59563.1| 464|Homo sapiens glucokinase protein.
Length = 464
Score = 124 bits (298), Expect = 4e-28
Identities = 64/164 (39%), Positives = 97/164 (59%), Gaps = 7/164 (4%)
Frame = +3
Query: 21 KIEARLSKLMLCGSTLRRVAEVFEKEIEAGLR---QQPSSLQMENTYVPELPDGTEEGSF 191
++E L++ L L++V +KE++ GLR + +S++M TYV P+G+E G F
Sbjct: 14 QVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEVGDF 73
Query: 192 LALDLGGTNFRVLFLELKAGQ--LLREKVKH--YHINDALRLGPGEDLFNFLADCVQDFL 359
L+LDLGGTNFRV+ +++ G+ K KH Y I + G E LF+++++C+ DFL
Sbjct: 74 LSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQTYSIPEDAMTGTAEMLFDYISECISDFL 133
Query: 360 VSQSMEKETFSLGFTFSFPMRQHSISSGELITWTKSFNCGGMDG 491
M+ + LGFTFSFP+R I G L+ WTK F G +G
Sbjct: 134 DKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEG 177
Score = 32.3 bits (70), Expect = 1.7
Identities = 23/76 (30%), Positives = 37/76 (48%), Gaps = 1/76 (1%)
Frame = +1
Query: 439 LEN*SLGRRASTAAEWTGFDVAALLQRCLSARS-LDVTVRVLLNDTTGTLVAGAHIDRNV 615
L N + G +AS A G +V LL+ + R ++ V ++NDT T+++ + D
Sbjct: 163 LLNWTKGFKASGAE---GNNVVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDHQC 219
Query: 616 GIXXDSGYRLNRCYME 663
+ G N CYME
Sbjct: 220 EVGMIVGTGCNACYME 235
>AF041022-3|AAB97682.1| 464|Homo sapiens glucokinase protein.
Length = 464
Score = 124 bits (298), Expect = 4e-28
Identities = 64/164 (39%), Positives = 97/164 (59%), Gaps = 7/164 (4%)
Frame = +3
Query: 21 KIEARLSKLMLCGSTLRRVAEVFEKEIEAGLR---QQPSSLQMENTYVPELPDGTEEGSF 191
++E L++ L L++V +KE++ GLR + +S++M TYV P+G+E G F
Sbjct: 14 QVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEVGDF 73
Query: 192 LALDLGGTNFRVLFLELKAGQ--LLREKVKH--YHINDALRLGPGEDLFNFLADCVQDFL 359
L+LDLGGTNFRV+ +++ G+ K KH Y I + G E LF+++++C+ DFL
Sbjct: 74 LSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECISDFL 133
Query: 360 VSQSMEKETFSLGFTFSFPMRQHSISSGELITWTKSFNCGGMDG 491
M+ + LGFTFSFP+R I G L+ WTK F G +G
Sbjct: 134 DKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEG 177
Score = 32.3 bits (70), Expect = 1.7
Identities = 23/76 (30%), Positives = 37/76 (48%), Gaps = 1/76 (1%)
Frame = +1
Query: 439 LEN*SLGRRASTAAEWTGFDVAALLQRCLSARS-LDVTVRVLLNDTTGTLVAGAHIDRNV 615
L N + G +AS A G +V LL+ + R ++ V ++NDT T+++ + D
Sbjct: 163 LLNWTKGFKASGAE---GNNVVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDHQC 219
Query: 616 GIXXDSGYRLNRCYME 663
+ G N CYME
Sbjct: 220 EVGMIVGTGCNACYME 235
>AF041022-2|AAB97681.1| 466|Homo sapiens glucokinase protein.
Length = 466
Score = 123 bits (297), Expect = 5e-28
Identities = 64/163 (39%), Positives = 96/163 (58%), Gaps = 7/163 (4%)
Frame = +3
Query: 24 IEARLSKLMLCGSTLRRVAEVFEKEIEAGLR---QQPSSLQMENTYVPELPDGTEEGSFL 194
+E L++ L L++V +KE++ GLR + +S++M TYV P+G+E G FL
Sbjct: 17 VEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEVGDFL 76
Query: 195 ALDLGGTNFRVLFLELKAGQ--LLREKVKH--YHINDALRLGPGEDLFNFLADCVQDFLV 362
+LDLGGTNFRV+ +++ G+ K KH Y I + G E LF+++++C+ DFL
Sbjct: 77 SLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECISDFLD 136
Query: 363 SQSMEKETFSLGFTFSFPMRQHSISSGELITWTKSFNCGGMDG 491
M+ + LGFTFSFP+R I G L+ WTK F G +G
Sbjct: 137 KHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEG 179
Score = 32.3 bits (70), Expect = 1.7
Identities = 23/76 (30%), Positives = 37/76 (48%), Gaps = 1/76 (1%)
Frame = +1
Query: 439 LEN*SLGRRASTAAEWTGFDVAALLQRCLSARS-LDVTVRVLLNDTTGTLVAGAHIDRNV 615
L N + G +AS A G +V LL+ + R ++ V ++NDT T+++ + D
Sbjct: 165 LLNWTKGFKASGAE---GNNVVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDHQC 221
Query: 616 GIXXDSGYRLNRCYME 663
+ G N CYME
Sbjct: 222 EVGMIVGTGCNACYME 237
>BC110505-1|AAI10506.2| 917|Homo sapiens hexokinase domain
containing 1 protein.
Length = 917
Score = 122 bits (294), Expect = 1e-27
Identities = 71/169 (42%), Positives = 100/169 (59%), Gaps = 6/169 (3%)
Frame = +3
Query: 3 NRLRAQK--IEARLSKLMLCGSTLRRVAEVFEKEIEAGLRQQPSSL---QMENTYVPELP 167
+R++AQ+ I+ L+ L L V E+E GL+++ L +M TYV LP
Sbjct: 461 SRVQAQRKQIDRVLALFQLTREQLVDVQAKMRAELEYGLKKKSHGLATVRMLPTYVCGLP 520
Query: 168 DGTEEGSFLALDLGGTNFRVLFLELKAGQL-LREKVKHYHINDALRLGPGEDLFNFLADC 344
DGTE+G FLALDLGGTNFRVL +++++G+ +R K + I + G GE+LF+ + C
Sbjct: 521 DGTEKGKFLALDLGGTNFRVLLVKIRSGRRSVRMYNKIFAIPLEIMQGTGEELFDHIVQC 580
Query: 345 VQDFLVSQSMEKETFSLGFTFSFPMRQHSISSGELITWTKSFNCGGMDG 491
+ DFL ++ + LGFTFSFP RQ SI G LI WTK F +G
Sbjct: 581 IADFLDYMGLKGASLPLGFTFSFPCRQMSIDKGTLIGWTKGFKATDCEG 629
Score = 108 bits (259), Expect = 2e-23
Identities = 55/161 (34%), Positives = 96/161 (59%), Gaps = 5/161 (3%)
Frame = +3
Query: 18 QKIEARLSKLMLCGSTLRRVAEVFEKEIEAGLRQQPS---SLQMENTYVPELPDGTEEGS 188
+K++ L + L TL + F E+E GL + + +++M T+V +PDG+E G
Sbjct: 20 KKVDRFLYHMRLSDDTLLDIMRRFRAEMEKGLAKDTNPTAAVKMLPTFVRAIPDGSENGE 79
Query: 189 FLALDLGGTNFRVLFLEL--KAGQLLREKVKHYHINDALRLGPGEDLFNFLADCVQDFLV 362
FL+LDLGG+ FRVL +++ + + ++ + + Y + + G G +LF ++ADC+ DF+
Sbjct: 80 FLSLDLGGSKFRVLKVQVAEEGKRHVQMESQFYPTPNEIIRGNGTELFEYVADCLADFMK 139
Query: 363 SQSMEKETFSLGFTFSFPMRQHSISSGELITWTKSFNCGGM 485
++ ++ + LG TFSFP RQ + G L++WTK F G+
Sbjct: 140 TKDLKHKKLPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGV 180
Score = 40.3 bits (90), Expect = 0.006
Identities = 21/64 (32%), Positives = 34/64 (53%), Gaps = 1/64 (1%)
Frame = +1
Query: 475 AAEWTGFDVAALLQRCLSARS-LDVTVRVLLNDTTGTLVAGAHIDRNVGIXXDSGYRLNR 651
A + G DV +L+ + R+ D+ + ++NDT GT++ + D N I +G N
Sbjct: 624 ATDCEGEDVVDMLREAIKRRNEFDLDIVAVVNDTVGTMMTCGYEDPNCEIGLIAGTGSNM 683
Query: 652 CYME 663
CYME
Sbjct: 684 CYME 687
Score = 36.3 bits (80), Expect = 0.11
Identities = 19/57 (33%), Positives = 30/57 (52%), Gaps = 1/57 (1%)
Frame = +1
Query: 496 DVAALLQRCLSA-RSLDVTVRVLLNDTTGTLVAGAHIDRNVGIXXDSGYRLNRCYME 663
DV + L + + + +DV + L+NDT GT++ A+ D + G N CYME
Sbjct: 184 DVVSRLTKAMRRHKDMDVDILALVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYME 240
>BC110504-1|AAI10505.1| 917|Homo sapiens hexokinase domain
containing 1 protein.
Length = 917
Score = 122 bits (294), Expect = 1e-27
Identities = 71/169 (42%), Positives = 100/169 (59%), Gaps = 6/169 (3%)
Frame = +3
Query: 3 NRLRAQK--IEARLSKLMLCGSTLRRVAEVFEKEIEAGLRQQPSSL---QMENTYVPELP 167
+R++AQ+ I+ L+ L L V E+E GL+++ L +M TYV LP
Sbjct: 461 SRVQAQRKQIDRVLALFQLTREQLVDVQAKMRAELEYGLKKKSHGLATVRMLPTYVCGLP 520
Query: 168 DGTEEGSFLALDLGGTNFRVLFLELKAGQL-LREKVKHYHINDALRLGPGEDLFNFLADC 344
DGTE+G FLALDLGGTNFRVL +++++G+ +R K + I + G GE+LF+ + C
Sbjct: 521 DGTEKGKFLALDLGGTNFRVLLVKIRSGRRSVRMYNKIFAIPLEIMQGTGEELFDHIVQC 580
Query: 345 VQDFLVSQSMEKETFSLGFTFSFPMRQHSISSGELITWTKSFNCGGMDG 491
+ DFL ++ + LGFTFSFP RQ SI G LI WTK F +G
Sbjct: 581 IADFLDYMGLKGASLPLGFTFSFPCRQMSIDKGTLIGWTKGFKATDCEG 629
Score = 108 bits (259), Expect = 2e-23
Identities = 55/161 (34%), Positives = 96/161 (59%), Gaps = 5/161 (3%)
Frame = +3
Query: 18 QKIEARLSKLMLCGSTLRRVAEVFEKEIEAGLRQQPS---SLQMENTYVPELPDGTEEGS 188
+K++ L + L TL + F E+E GL + + +++M T+V +PDG+E G
Sbjct: 20 KKVDRFLYHMRLSDDTLLDIMRRFRAEMEKGLAKDTNPTAAVKMLPTFVRAIPDGSENGE 79
Query: 189 FLALDLGGTNFRVLFLEL--KAGQLLREKVKHYHINDALRLGPGEDLFNFLADCVQDFLV 362
FL+LDLGG+ FRVL +++ + + ++ + + Y + + G G +LF ++ADC+ DF+
Sbjct: 80 FLSLDLGGSKFRVLKVQVAEEGKRHVQMESQFYPTPNEIIRGNGTELFEYVADCLADFMK 139
Query: 363 SQSMEKETFSLGFTFSFPMRQHSISSGELITWTKSFNCGGM 485
++ ++ + LG TFSFP RQ + G L++WTK F G+
Sbjct: 140 TKDLKHKKLPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGV 180
Score = 40.3 bits (90), Expect = 0.006
Identities = 21/64 (32%), Positives = 34/64 (53%), Gaps = 1/64 (1%)
Frame = +1
Query: 475 AAEWTGFDVAALLQRCLSARS-LDVTVRVLLNDTTGTLVAGAHIDRNVGIXXDSGYRLNR 651
A + G DV +L+ + R+ D+ + ++NDT GT++ + D N I +G N
Sbjct: 624 ATDCEGEDVVDMLREAIKRRNEFDLDIVAVVNDTVGTMMTCGYEDPNCEIGLIAGTGSNM 683
Query: 652 CYME 663
CYME
Sbjct: 684 CYME 687
Score = 36.3 bits (80), Expect = 0.11
Identities = 19/57 (33%), Positives = 30/57 (52%), Gaps = 1/57 (1%)
Frame = +1
Query: 496 DVAALLQRCLSA-RSLDVTVRVLLNDTTGTLVAGAHIDRNVGIXXDSGYRLNRCYME 663
DV + L + + + +DV + L+NDT GT++ A+ D + G N CYME
Sbjct: 184 DVVSRLTKAMRRHKDMDVDILALVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYME 240
>BC012337-1|AAH12337.1| 677|Homo sapiens HKDC1 protein protein.
Length = 677
Score = 122 bits (294), Expect = 1e-27
Identities = 71/169 (42%), Positives = 100/169 (59%), Gaps = 6/169 (3%)
Frame = +3
Query: 3 NRLRAQK--IEARLSKLMLCGSTLRRVAEVFEKEIEAGLRQQPSSL---QMENTYVPELP 167
+R++AQ+ I+ L+ L L V E+E GL+++ L +M TYV LP
Sbjct: 221 SRVQAQRKQIDRVLALFQLTREQLVDVQAKMRAELEYGLKKKSHGLATVRMLPTYVCGLP 280
Query: 168 DGTEEGSFLALDLGGTNFRVLFLELKAGQL-LREKVKHYHINDALRLGPGEDLFNFLADC 344
DGTE+G FLALDLGGTNFRVL +++++G+ +R K + I + G GE+LF+ + C
Sbjct: 281 DGTEKGKFLALDLGGTNFRVLLVKIRSGRRSVRMYNKIFAIPLEIMQGTGEELFDHIVQC 340
Query: 345 VQDFLVSQSMEKETFSLGFTFSFPMRQHSISSGELITWTKSFNCGGMDG 491
+ DFL ++ + LGFTFSFP RQ SI G LI WTK F +G
Sbjct: 341 IADFLDYMGLKGASLPLGFTFSFPCRQMSIDKGTLIGWTKGFKATDCEG 389
Score = 40.3 bits (90), Expect = 0.006
Identities = 21/64 (32%), Positives = 34/64 (53%), Gaps = 1/64 (1%)
Frame = +1
Query: 475 AAEWTGFDVAALLQRCLSARS-LDVTVRVLLNDTTGTLVAGAHIDRNVGIXXDSGYRLNR 651
A + G DV +L+ + R+ D+ + ++NDT GT++ + D N I +G N
Sbjct: 384 ATDCEGEDVVDMLREAIKRRNEFDLDIVAVVNDTVGTMMTCGYEDPNCEIGLIAGTGSNM 443
Query: 652 CYME 663
CYME
Sbjct: 444 CYME 447
>AL596223-3|CAH71500.1| 917|Homo sapiens hexokinase domain
containing 1 protein.
Length = 917
Score = 122 bits (294), Expect = 1e-27
Identities = 71/169 (42%), Positives = 100/169 (59%), Gaps = 6/169 (3%)
Frame = +3
Query: 3 NRLRAQK--IEARLSKLMLCGSTLRRVAEVFEKEIEAGLRQQPSSL---QMENTYVPELP 167
+R++AQ+ I+ L+ L L V E+E GL+++ L +M TYV LP
Sbjct: 461 SRVQAQRKQIDRVLALFQLTREQLVDVQAKMRAELEYGLKKKSHGLATVRMLPTYVCGLP 520
Query: 168 DGTEEGSFLALDLGGTNFRVLFLELKAGQL-LREKVKHYHINDALRLGPGEDLFNFLADC 344
DGTE+G FLALDLGGTNFRVL +++++G+ +R K + I + G GE+LF+ + C
Sbjct: 521 DGTEKGKFLALDLGGTNFRVLLVKIRSGRRSVRMYNKIFAIPLEIMQGTGEELFDHIVQC 580
Query: 345 VQDFLVSQSMEKETFSLGFTFSFPMRQHSISSGELITWTKSFNCGGMDG 491
+ DFL ++ + LGFTFSFP RQ SI G LI WTK F +G
Sbjct: 581 IADFLDYMGLKGASLPLGFTFSFPCRQMSIDKGTLIGWTKGFKATDCEG 629
Score = 108 bits (259), Expect = 2e-23
Identities = 55/161 (34%), Positives = 96/161 (59%), Gaps = 5/161 (3%)
Frame = +3
Query: 18 QKIEARLSKLMLCGSTLRRVAEVFEKEIEAGLRQQPS---SLQMENTYVPELPDGTEEGS 188
+K++ L + L TL + F E+E GL + + +++M T+V +PDG+E G
Sbjct: 20 KKVDRFLYHMRLSDDTLLDIMRRFRAEMEKGLAKDTNPTAAVKMLPTFVRAIPDGSENGE 79
Query: 189 FLALDLGGTNFRVLFLEL--KAGQLLREKVKHYHINDALRLGPGEDLFNFLADCVQDFLV 362
FL+LDLGG+ FRVL +++ + + ++ + + Y + + G G +LF ++ADC+ DF+
Sbjct: 80 FLSLDLGGSKFRVLKVQVAEEGKRHVQMESQFYPTPNEIIRGNGTELFEYVADCLADFMK 139
Query: 363 SQSMEKETFSLGFTFSFPMRQHSISSGELITWTKSFNCGGM 485
++ ++ + LG TFSFP RQ + G L++WTK F G+
Sbjct: 140 TKDLKHKKLPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGV 180
Score = 40.3 bits (90), Expect = 0.006
Identities = 21/64 (32%), Positives = 34/64 (53%), Gaps = 1/64 (1%)
Frame = +1
Query: 475 AAEWTGFDVAALLQRCLSARS-LDVTVRVLLNDTTGTLVAGAHIDRNVGIXXDSGYRLNR 651
A + G DV +L+ + R+ D+ + ++NDT GT++ + D N I +G N
Sbjct: 624 ATDCEGEDVVDMLREAIKRRNEFDLDIVAVVNDTVGTMMTCGYEDPNCEIGLIAGTGSNM 683
Query: 652 CYME 663
CYME
Sbjct: 684 CYME 687
Score = 36.3 bits (80), Expect = 0.11
Identities = 19/57 (33%), Positives = 30/57 (52%), Gaps = 1/57 (1%)
Frame = +1
Query: 496 DVAALLQRCLSA-RSLDVTVRVLLNDTTGTLVAGAHIDRNVGIXXDSGYRLNRCYME 663
DV + L + + + +DV + L+NDT GT++ A+ D + G N CYME
Sbjct: 184 DVVSRLTKAMRRHKDMDVDILALVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYME 240
>AK026414-1|BAB15478.1| 325|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22761 fis, clone KAIA0893. ).
Length = 325
Score = 122 bits (294), Expect = 1e-27
Identities = 71/169 (42%), Positives = 100/169 (59%), Gaps = 6/169 (3%)
Frame = +3
Query: 3 NRLRAQK--IEARLSKLMLCGSTLRRVAEVFEKEIEAGLRQQPSSL---QMENTYVPELP 167
+R++AQ+ I+ L+ L L V E+E GL+++ L +M TYV LP
Sbjct: 50 SRVQAQRKQIDRVLALFQLTREQLVDVQAKMRAELEYGLKKKSHGLATVRMLPTYVCGLP 109
Query: 168 DGTEEGSFLALDLGGTNFRVLFLELKAGQL-LREKVKHYHINDALRLGPGEDLFNFLADC 344
DGTE+G FLALDLGGTNFRVL +++++G+ +R K + I + G GE+LF+ + C
Sbjct: 110 DGTEKGKFLALDLGGTNFRVLLVKIRSGRRSVRMYNKIFAIPLEIMQGTGEELFDHIVQC 169
Query: 345 VQDFLVSQSMEKETFSLGFTFSFPMRQHSISSGELITWTKSFNCGGMDG 491
+ DFL ++ + LGFTFSFP RQ SI G LI WTK F +G
Sbjct: 170 IADFLDYMGLKGASLPLGFTFSFPCRQMSIDKGTLIGWTKGFKATDCEG 218
Score = 40.3 bits (90), Expect = 0.006
Identities = 21/64 (32%), Positives = 34/64 (53%), Gaps = 1/64 (1%)
Frame = +1
Query: 475 AAEWTGFDVAALLQRCLSARS-LDVTVRVLLNDTTGTLVAGAHIDRNVGIXXDSGYRLNR 651
A + G DV +L+ + R+ D+ + ++NDT GT++ + D N I +G N
Sbjct: 213 ATDCEGEDVVDMLREAIKRRNEFDLDIVAVVNDTVGTMMTCGYEDPNCEIGLIAGTGSNM 272
Query: 652 CYME 663
CYME
Sbjct: 273 CYME 276
>Z46376-1|CAA86511.1| 917|Homo sapiens Human hexokinase II cDNA
protein.
Length = 917
Score = 121 bits (292), Expect = 2e-27
Identities = 62/168 (36%), Positives = 100/168 (59%), Gaps = 5/168 (2%)
Frame = +3
Query: 3 NRLRAQKIEARLSKLMLCGSTLRRVAEVFEKEIEAGL---RQQPSSLQMENTYVPELPDG 173
N + QK++ L + L TL +++ F KE+E GL ++++M T+V PDG
Sbjct: 15 NHDQVQKVDQYLYHMRLSDETLLEISKRFRKEMEKGLGATTHPTAAVKMLPTFVRSTPDG 74
Query: 174 TEEGSFLALDLGGTNFRVLFLELKAGQLLREKVKH--YHINDALRLGPGEDLFNFLADCV 347
TE G FLALDLGGTNFRVL++++ L + ++++ Y I + + G G LF+ +A+C+
Sbjct: 75 TEHGEFLALDLGGTNFRVLWVKVTDNGLQKVEMENQIYAIPEDIMRGSGTQLFDHIAECL 134
Query: 348 QDFLVSQSMEKETFSLGFTFSFPMRQHSISSGELITWTKSFNCGGMDG 491
+F+ ++ + LGFTFSFP Q + L++WTK F G++G
Sbjct: 135 ANFMDKLQIKDKKLPLGFTFSFPCHQTKLDESFLVSWTKGFKSSGVEG 182
Score = 115 bits (277), Expect = 1e-25
Identities = 63/157 (40%), Positives = 89/157 (56%), Gaps = 5/157 (3%)
Frame = +3
Query: 36 LSKLMLCGSTLRRVAEVFEKEIEAGLRQQPSS---LQMENTYVPELPDGTEEGSFLALDL 206
L L L L V + E+E GL ++ + ++M TYV PDGTE+G FLALDL
Sbjct: 474 LEHLQLSHDQLLEVKRRMKVEMERGLSKETHASAPVKMLPTYVCATPDGTEKGDFLALDL 533
Query: 207 GGTNFRVLFLELKAGQL--LREKVKHYHINDALRLGPGEDLFNFLADCVQDFLVSQSMEK 380
GGTNFRVL + ++ G+ + K Y I + G G++LF+ + C+ DFL M+
Sbjct: 534 GGTNFRVLLVRVRNGKWGGVEMHNKIYAIPQEVMHGTGDELFDHIVQCIADFLEYMGMKG 593
Query: 381 ETFSLGFTFSFPMRQHSISSGELITWTKSFNCGGMDG 491
+ LGFTFSFP +Q+S+ L+ WTK F G +G
Sbjct: 594 VSLPLGFTFSFPCQQNSLDESILLKWTKGFKASGCEG 630
Score = 42.3 bits (95), Expect = 0.002
Identities = 21/59 (35%), Positives = 32/59 (54%), Gaps = 1/59 (1%)
Frame = +1
Query: 490 GFDVAALLQRCLSARS-LDVTVRVLLNDTTGTLVAGAHIDRNVGIXXDSGYRLNRCYME 663
G DV AL+++ + R D+ + ++NDT GT++ + D N I G N CYME
Sbjct: 182 GRDVVALIRKAIQRRGDFDIDIVAVVNDTVGTMMTCGYDDHNCEIGLIVGTGSNACYME 240
Score = 35.5 bits (78), Expect = 0.18
Identities = 20/59 (33%), Positives = 29/59 (49%), Gaps = 1/59 (1%)
Frame = +1
Query: 490 GFDVAALLQRCLSARS-LDVTVRVLLNDTTGTLVAGAHIDRNVGIXXDSGYRLNRCYME 663
G DV LL+ + R D+ V ++NDT GT++ D + + G N CYME
Sbjct: 630 GEDVVTLLKEAIHRREEFDLDVVAVVNDTVGTMMTCGFEDPHCEVGLIVGTGSNACYME 688
>BC064369-1|AAH64369.1| 917|Homo sapiens hexokinase 2 protein.
Length = 917
Score = 121 bits (292), Expect = 2e-27
Identities = 62/168 (36%), Positives = 100/168 (59%), Gaps = 5/168 (2%)
Frame = +3
Query: 3 NRLRAQKIEARLSKLMLCGSTLRRVAEVFEKEIEAGL---RQQPSSLQMENTYVPELPDG 173
N + QK++ L + L TL +++ F KE+E GL ++++M T+V PDG
Sbjct: 15 NHDQVQKVDQYLYHMRLSDETLLEISKRFRKEMEKGLGATTHPTAAVKMLPTFVRSTPDG 74
Query: 174 TEEGSFLALDLGGTNFRVLFLELKAGQLLREKVKH--YHINDALRLGPGEDLFNFLADCV 347
TE G FLALDLGGTNFRVL++++ L + ++++ Y I + + G G LF+ +A+C+
Sbjct: 75 TEHGEFLALDLGGTNFRVLWVKVTDNGLQKVEMENQIYAIPEDIMRGSGTQLFDHIAECL 134
Query: 348 QDFLVSQSMEKETFSLGFTFSFPMRQHSISSGELITWTKSFNCGGMDG 491
+F+ ++ + LGFTFSFP Q + L++WTK F G++G
Sbjct: 135 ANFMDKLQIKDKKLPLGFTFSFPCHQTKLDESFLVSWTKGFKSSGVEG 182
Score = 115 bits (277), Expect = 1e-25
Identities = 63/157 (40%), Positives = 89/157 (56%), Gaps = 5/157 (3%)
Frame = +3
Query: 36 LSKLMLCGSTLRRVAEVFEKEIEAGLRQQPSS---LQMENTYVPELPDGTEEGSFLALDL 206
L L L L V + E+E GL ++ + ++M TYV PDGTE+G FLALDL
Sbjct: 474 LEHLQLSHDQLLEVKRRMKVEMERGLSKETHASAPVKMLPTYVCATPDGTEKGDFLALDL 533
Query: 207 GGTNFRVLFLELKAGQL--LREKVKHYHINDALRLGPGEDLFNFLADCVQDFLVSQSMEK 380
GGTNFRVL + ++ G+ + K Y I + G G++LF+ + C+ DFL M+
Sbjct: 534 GGTNFRVLLVRVRNGKWGGVEMHNKIYAIPQEVMHGTGDELFDHIVQCIADFLEYMGMKG 593
Query: 381 ETFSLGFTFSFPMRQHSISSGELITWTKSFNCGGMDG 491
+ LGFTFSFP +Q+S+ L+ WTK F G +G
Sbjct: 594 VSLPLGFTFSFPCQQNSLDESILLKWTKGFKASGCEG 630
Score = 42.3 bits (95), Expect = 0.002
Identities = 21/59 (35%), Positives = 32/59 (54%), Gaps = 1/59 (1%)
Frame = +1
Query: 490 GFDVAALLQRCLSARS-LDVTVRVLLNDTTGTLVAGAHIDRNVGIXXDSGYRLNRCYME 663
G DV AL+++ + R D+ + ++NDT GT++ + D N I G N CYME
Sbjct: 182 GRDVVALIRKAIQRRGDFDIDIVAVVNDTVGTMMTCGYDDHNCEIGLIVGTGSNACYME 240
Score = 35.5 bits (78), Expect = 0.18
Identities = 20/59 (33%), Positives = 29/59 (49%), Gaps = 1/59 (1%)
Frame = +1
Query: 490 GFDVAALLQRCLSARS-LDVTVRVLLNDTTGTLVAGAHIDRNVGIXXDSGYRLNRCYME 663
G DV LL+ + R D+ V ++NDT GT++ D + + G N CYME
Sbjct: 630 GEDVVTLLKEAIHRREEFDLDVVAVVNDTVGTMMTCGFEDPHCEVGLIVGTGSNACYME 688
>BC021116-1|AAH21116.1| 917|Homo sapiens hexokinase 2 protein.
Length = 917
Score = 121 bits (292), Expect = 2e-27
Identities = 62/168 (36%), Positives = 100/168 (59%), Gaps = 5/168 (2%)
Frame = +3
Query: 3 NRLRAQKIEARLSKLMLCGSTLRRVAEVFEKEIEAGL---RQQPSSLQMENTYVPELPDG 173
N + QK++ L + L TL +++ F KE+E GL ++++M T+V PDG
Sbjct: 15 NHDQVQKVDQYLYHMRLSDETLLEISKRFRKEMEKGLGATTHPTAAVKMLPTFVRSTPDG 74
Query: 174 TEEGSFLALDLGGTNFRVLFLELKAGQLLREKVKH--YHINDALRLGPGEDLFNFLADCV 347
TE G FLALDLGGTNFRVL++++ L + ++++ Y I + + G G LF+ +A+C+
Sbjct: 75 TEHGEFLALDLGGTNFRVLWVKVTDNGLQKVEMENQIYAIPEDIMRGSGTQLFDHIAECL 134
Query: 348 QDFLVSQSMEKETFSLGFTFSFPMRQHSISSGELITWTKSFNCGGMDG 491
+F+ ++ + LGFTFSFP Q + L++WTK F G++G
Sbjct: 135 ANFMDKLQIKDKKLPLGFTFSFPCHQTKLDESFLVSWTKGFKSSGVEG 182
Score = 115 bits (277), Expect = 1e-25
Identities = 63/157 (40%), Positives = 89/157 (56%), Gaps = 5/157 (3%)
Frame = +3
Query: 36 LSKLMLCGSTLRRVAEVFEKEIEAGLRQQPSS---LQMENTYVPELPDGTEEGSFLALDL 206
L L L L V + E+E GL ++ + ++M TYV PDGTE+G FLALDL
Sbjct: 474 LEHLQLSHDQLLEVKRRMKVEMERGLSKETHASAPVKMLPTYVCATPDGTEKGDFLALDL 533
Query: 207 GGTNFRVLFLELKAGQL--LREKVKHYHINDALRLGPGEDLFNFLADCVQDFLVSQSMEK 380
GGTNFRVL + ++ G+ + K Y I + G G++LF+ + C+ DFL M+
Sbjct: 534 GGTNFRVLLVRVRNGKWGGVEMHNKIYAIPQEVMHGTGDELFDHIVQCIADFLEYMGMKG 593
Query: 381 ETFSLGFTFSFPMRQHSISSGELITWTKSFNCGGMDG 491
+ LGFTFSFP +Q+S+ L+ WTK F G +G
Sbjct: 594 VSLPLGFTFSFPCQQNSLDESILLKWTKGFKASGCEG 630
Score = 42.3 bits (95), Expect = 0.002
Identities = 21/59 (35%), Positives = 32/59 (54%), Gaps = 1/59 (1%)
Frame = +1
Query: 490 GFDVAALLQRCLSARS-LDVTVRVLLNDTTGTLVAGAHIDRNVGIXXDSGYRLNRCYME 663
G DV AL+++ + R D+ + ++NDT GT++ + D N I G N CYME
Sbjct: 182 GRDVVALIRKAIQRRGDFDIDIVAVVNDTVGTMMTCGYDDHNCEIGLIVGTGSNACYME 240
Score = 35.5 bits (78), Expect = 0.18
Identities = 20/59 (33%), Positives = 29/59 (49%), Gaps = 1/59 (1%)
Frame = +1
Query: 490 GFDVAALLQRCLSARS-LDVTVRVLLNDTTGTLVAGAHIDRNVGIXXDSGYRLNRCYME 663
G DV LL+ + R D+ V ++NDT GT++ D + + G N CYME
Sbjct: 630 GEDVVTLLKEAIHRREEFDLDVVAVVNDTVGTMMTCGFEDPHCEVGLIVGTGSNACYME 688
>AY623118-1|AAT38114.1| 917|Homo sapiens hexokinase 2 protein.
Length = 917
Score = 121 bits (292), Expect = 2e-27
Identities = 62/168 (36%), Positives = 100/168 (59%), Gaps = 5/168 (2%)
Frame = +3
Query: 3 NRLRAQKIEARLSKLMLCGSTLRRVAEVFEKEIEAGL---RQQPSSLQMENTYVPELPDG 173
N + QK++ L + L TL +++ F KE+E GL ++++M T+V PDG
Sbjct: 15 NHDQVQKVDQYLYHMRLSDETLLEISKRFRKEMEKGLGATTHPTAAVKMLPTFVRSTPDG 74
Query: 174 TEEGSFLALDLGGTNFRVLFLELKAGQLLREKVKH--YHINDALRLGPGEDLFNFLADCV 347
TE G FLALDLGGTNFRVL++++ L + ++++ Y I + + G G LF+ +A+C+
Sbjct: 75 TEHGEFLALDLGGTNFRVLWVKVTDNGLQKVEMENQIYAIPEDIMRGSGTQLFDHIAECL 134
Query: 348 QDFLVSQSMEKETFSLGFTFSFPMRQHSISSGELITWTKSFNCGGMDG 491
+F+ ++ + LGFTFSFP Q + L++WTK F G++G
Sbjct: 135 ANFMDKLQIKDKKLPLGFTFSFPCHQTKLDESFLVSWTKGFKSSGVEG 182
Score = 115 bits (277), Expect = 1e-25
Identities = 63/157 (40%), Positives = 89/157 (56%), Gaps = 5/157 (3%)
Frame = +3
Query: 36 LSKLMLCGSTLRRVAEVFEKEIEAGLRQQPSS---LQMENTYVPELPDGTEEGSFLALDL 206
L L L L V + E+E GL ++ + ++M TYV PDGTE+G FLALDL
Sbjct: 474 LEHLQLSHDQLLEVKRRMKVEMERGLSKETHASAPVKMLPTYVCATPDGTEKGDFLALDL 533
Query: 207 GGTNFRVLFLELKAGQL--LREKVKHYHINDALRLGPGEDLFNFLADCVQDFLVSQSMEK 380
GGTNFRVL + ++ G+ + K Y I + G G++LF+ + C+ DFL M+
Sbjct: 534 GGTNFRVLLVRVRNGKWGGVEMHNKIYAIPQEVMHGTGDELFDHIVQCIADFLEYMGMKG 593
Query: 381 ETFSLGFTFSFPMRQHSISSGELITWTKSFNCGGMDG 491
+ LGFTFSFP +Q+S+ L+ WTK F G +G
Sbjct: 594 VSLPLGFTFSFPCQQNSLDESILLKWTKGFKASGCEG 630
Score = 42.3 bits (95), Expect = 0.002
Identities = 21/59 (35%), Positives = 32/59 (54%), Gaps = 1/59 (1%)
Frame = +1
Query: 490 GFDVAALLQRCLSARS-LDVTVRVLLNDTTGTLVAGAHIDRNVGIXXDSGYRLNRCYME 663
G DV AL+++ + R D+ + ++NDT GT++ + D N I G N CYME
Sbjct: 182 GRDVVALIRKAIQRRGDFDIDIVAVVNDTVGTMMTCGYDDHNCEIGLIVGTGSNACYME 240
Score = 35.5 bits (78), Expect = 0.18
Identities = 20/59 (33%), Positives = 29/59 (49%), Gaps = 1/59 (1%)
Frame = +1
Query: 490 GFDVAALLQRCLSARS-LDVTVRVLLNDTTGTLVAGAHIDRNVGIXXDSGYRLNRCYME 663
G DV LL+ + R D+ V ++NDT GT++ D + + G N CYME
Sbjct: 630 GEDVVTLLKEAIHRREEFDLDVVAVVNDTVGTMMTCGFEDPHCEVGLIVGTGSNACYME 688
>AF148513-1|AAD30174.1| 917|Homo sapiens hexokinase II protein.
Length = 917
Score = 121 bits (292), Expect = 2e-27
Identities = 62/168 (36%), Positives = 100/168 (59%), Gaps = 5/168 (2%)
Frame = +3
Query: 3 NRLRAQKIEARLSKLMLCGSTLRRVAEVFEKEIEAGL---RQQPSSLQMENTYVPELPDG 173
N + QK++ L + L TL +++ F KE+E GL ++++M T+V PDG
Sbjct: 15 NHDQVQKVDQYLYHMRLSDETLLEISKRFRKEMEKGLGATTHPTAAVKMLPTFVRSTPDG 74
Query: 174 TEEGSFLALDLGGTNFRVLFLELKAGQLLREKVKH--YHINDALRLGPGEDLFNFLADCV 347
TE G FLALDLGGTNFRVL++++ L + ++++ Y I + + G G LF+ +A+C+
Sbjct: 75 TEHGEFLALDLGGTNFRVLWVKVTDNGLQKVEMENQIYAIPEDIMRGSGTQLFDHIAECL 134
Query: 348 QDFLVSQSMEKETFSLGFTFSFPMRQHSISSGELITWTKSFNCGGMDG 491
+F+ ++ + LGFTFSFP Q + L++WTK F G++G
Sbjct: 135 ANFMDKLQIKDKKLPLGFTFSFPCHQTKLDESFLVSWTKGFKSSGVEG 182
Score = 115 bits (277), Expect = 1e-25
Identities = 63/157 (40%), Positives = 89/157 (56%), Gaps = 5/157 (3%)
Frame = +3
Query: 36 LSKLMLCGSTLRRVAEVFEKEIEAGLRQQPSS---LQMENTYVPELPDGTEEGSFLALDL 206
L L L L V + E+E GL ++ + ++M TYV PDGTE+G FLALDL
Sbjct: 474 LEHLQLSHDQLLEVKRRMKVEMERGLSKETHASAPVKMLPTYVCATPDGTEKGDFLALDL 533
Query: 207 GGTNFRVLFLELKAGQL--LREKVKHYHINDALRLGPGEDLFNFLADCVQDFLVSQSMEK 380
GGTNFRVL + ++ G+ + K Y I + G G++LF+ + C+ DFL M+
Sbjct: 534 GGTNFRVLLVRVRNGKWGGVEMHNKIYAIPQEVMHGTGDELFDHIVQCIADFLEYMGMKG 593
Query: 381 ETFSLGFTFSFPMRQHSISSGELITWTKSFNCGGMDG 491
+ LGFTFSFP +Q+S+ L+ WTK F G +G
Sbjct: 594 VSLPLGFTFSFPCQQNSLDESILLKWTKGFKASGCEG 630
Score = 42.3 bits (95), Expect = 0.002
Identities = 21/59 (35%), Positives = 32/59 (54%), Gaps = 1/59 (1%)
Frame = +1
Query: 490 GFDVAALLQRCLSARS-LDVTVRVLLNDTTGTLVAGAHIDRNVGIXXDSGYRLNRCYME 663
G DV AL+++ + R D+ + ++NDT GT++ + D N I G N CYME
Sbjct: 182 GRDVVALIRKAIQRRGDFDIDIVAVVNDTVGTMMTCGYDDHNCEIGLIVGTGSNACYME 240
Score = 35.5 bits (78), Expect = 0.18
Identities = 20/59 (33%), Positives = 29/59 (49%), Gaps = 1/59 (1%)
Frame = +1
Query: 490 GFDVAALLQRCLSARS-LDVTVRVLLNDTTGTLVAGAHIDRNVGIXXDSGYRLNRCYME 663
G DV LL+ + R D+ V ++NDT GT++ D + + G N CYME
Sbjct: 630 GEDVVTLLKEAIHRREEFDLDVVAVVNDTVGTMMTCGFEDPHCEVGLIVGTGSNACYME 688
>AC019069-1|AAX93084.1| 344|Homo sapiens unknown protein.
Length = 344
Score = 121 bits (292), Expect = 2e-27
Identities = 62/168 (36%), Positives = 100/168 (59%), Gaps = 5/168 (2%)
Frame = +3
Query: 3 NRLRAQKIEARLSKLMLCGSTLRRVAEVFEKEIEAGL---RQQPSSLQMENTYVPELPDG 173
N + QK++ L + L TL +++ F KE+E GL ++++M T+V PDG
Sbjct: 15 NHDQVQKVDQYLYHMRLSDETLLEISKRFRKEMEKGLGATTHPTAAVKMLPTFVRSTPDG 74
Query: 174 TEEGSFLALDLGGTNFRVLFLELKAGQLLREKVKH--YHINDALRLGPGEDLFNFLADCV 347
TE G FLALDLGGTNFRVL++++ L + ++++ Y I + + G G LF+ +A+C+
Sbjct: 75 TEHGEFLALDLGGTNFRVLWVKVTDNGLQKVEMENQIYAIPEDIMRGSGTQLFDHIAECL 134
Query: 348 QDFLVSQSMEKETFSLGFTFSFPMRQHSISSGELITWTKSFNCGGMDG 491
+F+ ++ + LGFTFSFP Q + L++WTK F G++G
Sbjct: 135 ANFMDKLQIKDKKLPLGFTFSFPCHQTKLDESFLVSWTKGFKSSGVEG 182
Score = 42.3 bits (95), Expect = 0.002
Identities = 21/59 (35%), Positives = 32/59 (54%), Gaps = 1/59 (1%)
Frame = +1
Query: 490 GFDVAALLQRCLSARS-LDVTVRVLLNDTTGTLVAGAHIDRNVGIXXDSGYRLNRCYME 663
G DV AL+++ + R D+ + ++NDT GT++ + D N I G N CYME
Sbjct: 182 GRDVVALIRKAIQRRGDFDIDIVAVVNDTVGTMMTCGYDDHNCEIGLIVGTGSNACYME 240
>Z46354-1|CAA86476.2| 916|Homo sapiens hexokinase II protein.
Length = 916
Score = 121 bits (291), Expect = 3e-27
Identities = 62/168 (36%), Positives = 100/168 (59%), Gaps = 5/168 (2%)
Frame = +3
Query: 3 NRLRAQKIEARLSKLMLCGSTLRRVAEVFEKEIEAGL---RQQPSSLQMENTYVPELPDG 173
N + QK++ L + L TL +++ F KE+E GL ++++M T+V PDG
Sbjct: 15 NHDQVQKVDQYLYHMRLSDETLLEISKRFRKEMEKGLGATTHPTAAVKMLPTFVRSTPDG 74
Query: 174 TEEGSFLALDLGGTNFRVLFLELKAGQLLREKVKH--YHINDALRLGPGEDLFNFLADCV 347
TE G FLALDLGGTNFRVL++++ L + ++++ Y I + + G G LF+ +A+C+
Sbjct: 75 TEHGEFLALDLGGTNFRVLWVKVTDNGLQKVEMENQIYAIPEDIMRGSGTQLFDHIAECL 134
Query: 348 QDFLVSQSMEKETFSLGFTFSFPMRQHSISSGELITWTKSFNCGGMDG 491
+F+ ++ + LGFTFSFP Q + L++WTK F G++G
Sbjct: 135 ANFMDKLHIKDKKLPLGFTFSFPCHQTKLDESFLVSWTKGFKSSGVEG 182
Score = 115 bits (277), Expect = 1e-25
Identities = 63/157 (40%), Positives = 89/157 (56%), Gaps = 5/157 (3%)
Frame = +3
Query: 36 LSKLMLCGSTLRRVAEVFEKEIEAGLRQQPSS---LQMENTYVPELPDGTEEGSFLALDL 206
L L L L V + E+E GL ++ + ++M TYV PDGTE+G FLALDL
Sbjct: 474 LEHLQLSHDQLLEVKRRMKVEMERGLSKETHASAPVKMLPTYVCATPDGTEKGDFLALDL 533
Query: 207 GGTNFRVLFLELKAGQL--LREKVKHYHINDALRLGPGEDLFNFLADCVQDFLVSQSMEK 380
GGTNFRVL + ++ G+ + K Y I + G G++LF+ + C+ DFL M+
Sbjct: 534 GGTNFRVLLVRVRNGKWGGVEMHNKIYAIPQEVMHGTGDELFDHIVQCIADFLEYMGMKG 593
Query: 381 ETFSLGFTFSFPMRQHSISSGELITWTKSFNCGGMDG 491
+ LGFTFSFP +Q+S+ L+ WTK F G +G
Sbjct: 594 VSLPLGFTFSFPCQQNSLDESILLKWTKGFKASGCEG 630
Score = 42.3 bits (95), Expect = 0.002
Identities = 21/59 (35%), Positives = 32/59 (54%), Gaps = 1/59 (1%)
Frame = +1
Query: 490 GFDVAALLQRCLSARS-LDVTVRVLLNDTTGTLVAGAHIDRNVGIXXDSGYRLNRCYME 663
G DV AL+++ + R D+ + ++NDT GT++ + D N I G N CYME
Sbjct: 182 GRDVVALIRKAIQRRGDFDIDIVAVVNDTVGTMMTCGYDDHNCEIGLIVGTGSNACYME 240
Score = 35.5 bits (78), Expect = 0.18
Identities = 20/59 (33%), Positives = 29/59 (49%), Gaps = 1/59 (1%)
Frame = +1
Query: 490 GFDVAALLQRCLSARS-LDVTVRVLLNDTTGTLVAGAHIDRNVGIXXDSGYRLNRCYME 663
G DV LL+ + R D+ V ++NDT GT++ D + + G N CYME
Sbjct: 630 GEDVVTLLKEAIHRREEFDLDVVAVVNDTVGTMMTCGFEDPHCEVGLIVGTGSNACYME 688
>X66957-1|CAA47379.1| 631|Homo sapiens hexokinase type 1 protein.
Length = 631
Score = 120 bits (290), Expect = 4e-27
Identities = 69/167 (41%), Positives = 99/167 (59%), Gaps = 8/167 (4%)
Frame = +3
Query: 18 QKIEARLSKLMLCGSTLRRVAEVFEKEIEAGLRQQPSS---LQMENTYVPELPDGTEEGS 188
++IE L+ L L V + E+E GLR+Q + ++M ++V PDGTE G
Sbjct: 182 RQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTENGD 241
Query: 189 FLALDLGGTNFRVLFLELKAGQLLREKV--KHYHINDALRLGPGEDLFNFLADCVQDFLV 362
FLALDLGGTNFRVL +++++G+ ++ K Y I + G GE+LF+ + C+ DFL
Sbjct: 242 FLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLD 301
Query: 363 SQSMEKETFSLGFTFSFPMRQHSISSGELITWTKSF---NCGGMDGV 494
++ LGFTFSFP +Q S+ +G LITWTK F +C G D V
Sbjct: 302 YMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVV 348
Score = 38.3 bits (85), Expect = 0.026
Identities = 21/64 (32%), Positives = 32/64 (50%), Gaps = 1/64 (1%)
Frame = +1
Query: 475 AAEWTGFDVAALLQRCLSARS-LDVTVRVLLNDTTGTLVAGAHIDRNVGIXXDSGYRLNR 651
A + G DV LL+ + R D+ V ++NDT GT++ A+ + + G N
Sbjct: 339 ATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNA 398
Query: 652 CYME 663
CYME
Sbjct: 399 CYME 402
>M75126-1|AAA52646.1| 917|Homo sapiens hexokinase 1 protein.
Length = 917
Score = 120 bits (290), Expect = 4e-27
Identities = 69/167 (41%), Positives = 99/167 (59%), Gaps = 8/167 (4%)
Frame = +3
Query: 18 QKIEARLSKLMLCGSTLRRVAEVFEKEIEAGLRQQPSS---LQMENTYVPELPDGTEEGS 188
++IE L+ L L V + E+E GLR+Q + ++M ++V PDGTE G
Sbjct: 468 RQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTENGD 527
Query: 189 FLALDLGGTNFRVLFLELKAGQLLREKV--KHYHINDALRLGPGEDLFNFLADCVQDFLV 362
FLALDLGGTNFRVL +++++G+ ++ K Y I + G GE+LF+ + C+ DFL
Sbjct: 528 FLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLD 587
Query: 363 SQSMEKETFSLGFTFSFPMRQHSISSGELITWTKSF---NCGGMDGV 494
++ LGFTFSFP +Q S+ +G LITWTK F +C G D V
Sbjct: 588 YMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVV 634
Score = 111 bits (266), Expect = 3e-24
Identities = 57/165 (34%), Positives = 99/165 (60%), Gaps = 5/165 (3%)
Frame = +3
Query: 12 RAQKIEARLSKLMLCGSTLRRVAEVFEKEIEAGLRQQ---PSSLQMENTYVPELPDGTEE 182
+ +KI+ L + L TL + F KE++ GL + ++++M T+V +PDG+E+
Sbjct: 18 QVKKIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEK 77
Query: 183 GSFLALDLGGTNFRVLFLEL--KAGQLLREKVKHYHINDALRLGPGEDLFNFLADCVQDF 356
G F+ALDLGG++FR+L +++ + Q + + + Y + + G G LF+ +A+C+ DF
Sbjct: 78 GDFIALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDF 137
Query: 357 LVSQSMEKETFSLGFTFSFPMRQHSISSGELITWTKSFNCGGMDG 491
+ + ++ + +GFTFSFP +Q I LITWTK F G++G
Sbjct: 138 MEKRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEG 182
Score = 38.3 bits (85), Expect = 0.026
Identities = 19/59 (32%), Positives = 30/59 (50%), Gaps = 1/59 (1%)
Frame = +1
Query: 490 GFDVAALLQRCLSARS-LDVTVRVLLNDTTGTLVAGAHIDRNVGIXXDSGYRLNRCYME 663
G DV LL + + R D + ++NDT GT++ + D++ + G N CYME
Sbjct: 182 GADVVKLLNKAIKKRGDYDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYME 240
Score = 38.3 bits (85), Expect = 0.026
Identities = 21/64 (32%), Positives = 32/64 (50%), Gaps = 1/64 (1%)
Frame = +1
Query: 475 AAEWTGFDVAALLQRCLSARS-LDVTVRVLLNDTTGTLVAGAHIDRNVGIXXDSGYRLNR 651
A + G DV LL+ + R D+ V ++NDT GT++ A+ + + G N
Sbjct: 625 ATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNA 684
Query: 652 CYME 663
CYME
Sbjct: 685 CYME 688
>BC008730-1|AAH08730.1| 917|Homo sapiens hexokinase 1 protein.
Length = 917
Score = 120 bits (290), Expect = 4e-27
Identities = 69/167 (41%), Positives = 99/167 (59%), Gaps = 8/167 (4%)
Frame = +3
Query: 18 QKIEARLSKLMLCGSTLRRVAEVFEKEIEAGLRQQPSS---LQMENTYVPELPDGTEEGS 188
++IE L+ L L V + E+E GLR+Q + ++M ++V PDGTE G
Sbjct: 468 RQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTENGD 527
Query: 189 FLALDLGGTNFRVLFLELKAGQLLREKV--KHYHINDALRLGPGEDLFNFLADCVQDFLV 362
FLALDLGGTNFRVL +++++G+ ++ K Y I + G GE+LF+ + C+ DFL
Sbjct: 528 FLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLD 587
Query: 363 SQSMEKETFSLGFTFSFPMRQHSISSGELITWTKSF---NCGGMDGV 494
++ LGFTFSFP +Q S+ +G LITWTK F +C G D V
Sbjct: 588 YMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVV 634
Score = 111 bits (266), Expect = 3e-24
Identities = 57/165 (34%), Positives = 99/165 (60%), Gaps = 5/165 (3%)
Frame = +3
Query: 12 RAQKIEARLSKLMLCGSTLRRVAEVFEKEIEAGLRQQ---PSSLQMENTYVPELPDGTEE 182
+ +KI+ L + L TL + F KE++ GL + ++++M T+V +PDG+E+
Sbjct: 18 QVKKIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEK 77
Query: 183 GSFLALDLGGTNFRVLFLEL--KAGQLLREKVKHYHINDALRLGPGEDLFNFLADCVQDF 356
G F+ALDLGG++FR+L +++ + Q + + + Y + + G G LF+ +A+C+ DF
Sbjct: 78 GDFIALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDF 137
Query: 357 LVSQSMEKETFSLGFTFSFPMRQHSISSGELITWTKSFNCGGMDG 491
+ + ++ + +GFTFSFP +Q I LITWTK F G++G
Sbjct: 138 MEKRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEG 182
Score = 38.3 bits (85), Expect = 0.026
Identities = 19/59 (32%), Positives = 30/59 (50%), Gaps = 1/59 (1%)
Frame = +1
Query: 490 GFDVAALLQRCLSARS-LDVTVRVLLNDTTGTLVAGAHIDRNVGIXXDSGYRLNRCYME 663
G DV LL + + R D + ++NDT GT++ + D++ + G N CYME
Sbjct: 182 GADVVKLLNKAIKKRGDYDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYME 240
Score = 38.3 bits (85), Expect = 0.026
Identities = 21/64 (32%), Positives = 32/64 (50%), Gaps = 1/64 (1%)
Frame = +1
Query: 475 AAEWTGFDVAALLQRCLSARS-LDVTVRVLLNDTTGTLVAGAHIDRNVGIXXDSGYRLNR 651
A + G DV LL+ + R D+ V ++NDT GT++ A+ + + G N
Sbjct: 625 ATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNA 684
Query: 652 CYME 663
CYME
Sbjct: 685 CYME 688
>AL596223-9|CAH71506.1| 917|Homo sapiens hexokinase 1 protein.
Length = 917
Score = 120 bits (290), Expect = 4e-27
Identities = 69/167 (41%), Positives = 99/167 (59%), Gaps = 8/167 (4%)
Frame = +3
Query: 18 QKIEARLSKLMLCGSTLRRVAEVFEKEIEAGLRQQPSS---LQMENTYVPELPDGTEEGS 188
++IE L+ L L V + E+E GLR+Q + ++M ++V PDGTE G
Sbjct: 468 RQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTENGD 527
Query: 189 FLALDLGGTNFRVLFLELKAGQLLREKV--KHYHINDALRLGPGEDLFNFLADCVQDFLV 362
FLALDLGGTNFRVL +++++G+ ++ K Y I + G GE+LF+ + C+ DFL
Sbjct: 528 FLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLD 587
Query: 363 SQSMEKETFSLGFTFSFPMRQHSISSGELITWTKSF---NCGGMDGV 494
++ LGFTFSFP +Q S+ +G LITWTK F +C G D V
Sbjct: 588 YMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVV 634
Score = 111 bits (266), Expect = 3e-24
Identities = 57/165 (34%), Positives = 99/165 (60%), Gaps = 5/165 (3%)
Frame = +3
Query: 12 RAQKIEARLSKLMLCGSTLRRVAEVFEKEIEAGLRQQ---PSSLQMENTYVPELPDGTEE 182
+ +KI+ L + L TL + F KE++ GL + ++++M T+V +PDG+E+
Sbjct: 18 QVKKIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEK 77
Query: 183 GSFLALDLGGTNFRVLFLEL--KAGQLLREKVKHYHINDALRLGPGEDLFNFLADCVQDF 356
G F+ALDLGG++FR+L +++ + Q + + + Y + + G G LF+ +A+C+ DF
Sbjct: 78 GDFIALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDF 137
Query: 357 LVSQSMEKETFSLGFTFSFPMRQHSISSGELITWTKSFNCGGMDG 491
+ + ++ + +GFTFSFP +Q I LITWTK F G++G
Sbjct: 138 MEKRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEG 182
Score = 38.3 bits (85), Expect = 0.026
Identities = 19/59 (32%), Positives = 30/59 (50%), Gaps = 1/59 (1%)
Frame = +1
Query: 490 GFDVAALLQRCLSARS-LDVTVRVLLNDTTGTLVAGAHIDRNVGIXXDSGYRLNRCYME 663
G DV LL + + R D + ++NDT GT++ + D++ + G N CYME
Sbjct: 182 GADVVKLLNKAIKKRGDYDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYME 240
Score = 38.3 bits (85), Expect = 0.026
Identities = 21/64 (32%), Positives = 32/64 (50%), Gaps = 1/64 (1%)
Frame = +1
Query: 475 AAEWTGFDVAALLQRCLSARS-LDVTVRVLLNDTTGTLVAGAHIDRNVGIXXDSGYRLNR 651
A + G DV LL+ + R D+ V ++NDT GT++ A+ + + G N
Sbjct: 625 ATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNA 684
Query: 652 CYME 663
CYME
Sbjct: 685 CYME 688
>AF016365-4|AAC15862.1| 917|Homo sapiens hexokinase I protein.
Length = 917
Score = 120 bits (290), Expect = 4e-27
Identities = 69/167 (41%), Positives = 99/167 (59%), Gaps = 8/167 (4%)
Frame = +3
Query: 18 QKIEARLSKLMLCGSTLRRVAEVFEKEIEAGLRQQPSS---LQMENTYVPELPDGTEEGS 188
++IE L+ L L V + E+E GLR+Q + ++M ++V PDGTE G
Sbjct: 468 RQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTENGD 527
Query: 189 FLALDLGGTNFRVLFLELKAGQLLREKV--KHYHINDALRLGPGEDLFNFLADCVQDFLV 362
FLALDLGGTNFRVL +++++G+ ++ K Y I + G GE+LF+ + C+ DFL
Sbjct: 528 FLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLD 587
Query: 363 SQSMEKETFSLGFTFSFPMRQHSISSGELITWTKSF---NCGGMDGV 494
++ LGFTFSFP +Q S+ +G LITWTK F +C G D V
Sbjct: 588 YMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVV 634
Score = 111 bits (266), Expect = 3e-24
Identities = 57/165 (34%), Positives = 99/165 (60%), Gaps = 5/165 (3%)
Frame = +3
Query: 12 RAQKIEARLSKLMLCGSTLRRVAEVFEKEIEAGLRQQ---PSSLQMENTYVPELPDGTEE 182
+ +KI+ L + L TL + F KE++ GL + ++++M T+V +PDG+E+
Sbjct: 18 QVKKIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEK 77
Query: 183 GSFLALDLGGTNFRVLFLEL--KAGQLLREKVKHYHINDALRLGPGEDLFNFLADCVQDF 356
G F+ALDLGG++FR+L +++ + Q + + + Y + + G G LF+ +A+C+ DF
Sbjct: 78 GDFIALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDF 137
Query: 357 LVSQSMEKETFSLGFTFSFPMRQHSISSGELITWTKSFNCGGMDG 491
+ + ++ + +GFTFSFP +Q I LITWTK F G++G
Sbjct: 138 MEKRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEG 182
Score = 38.3 bits (85), Expect = 0.026
Identities = 19/59 (32%), Positives = 30/59 (50%), Gaps = 1/59 (1%)
Frame = +1
Query: 490 GFDVAALLQRCLSARS-LDVTVRVLLNDTTGTLVAGAHIDRNVGIXXDSGYRLNRCYME 663
G DV LL + + R D + ++NDT GT++ + D++ + G N CYME
Sbjct: 182 GADVVKLLNKAIKKRGDYDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYME 240
Score = 38.3 bits (85), Expect = 0.026
Identities = 21/64 (32%), Positives = 32/64 (50%), Gaps = 1/64 (1%)
Frame = +1
Query: 475 AAEWTGFDVAALLQRCLSARS-LDVTVRVLLNDTTGTLVAGAHIDRNVGIXXDSGYRLNR 651
A + G DV LL+ + R D+ V ++NDT GT++ A+ + + G N
Sbjct: 625 ATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNA 684
Query: 652 CYME 663
CYME
Sbjct: 685 CYME 688
>AF016365-3|AAC15863.1| 916|Homo sapiens hexokinase IR protein.
Length = 916
Score = 120 bits (290), Expect = 4e-27
Identities = 69/167 (41%), Positives = 99/167 (59%), Gaps = 8/167 (4%)
Frame = +3
Query: 18 QKIEARLSKLMLCGSTLRRVAEVFEKEIEAGLRQQPSS---LQMENTYVPELPDGTEEGS 188
++IE L+ L L V + E+E GLR+Q + ++M ++V PDGTE G
Sbjct: 467 RQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTENGD 526
Query: 189 FLALDLGGTNFRVLFLELKAGQLLREKV--KHYHINDALRLGPGEDLFNFLADCVQDFLV 362
FLALDLGGTNFRVL +++++G+ ++ K Y I + G GE+LF+ + C+ DFL
Sbjct: 527 FLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLD 586
Query: 363 SQSMEKETFSLGFTFSFPMRQHSISSGELITWTKSF---NCGGMDGV 494
++ LGFTFSFP +Q S+ +G LITWTK F +C G D V
Sbjct: 587 YMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVV 633
Score = 108 bits (259), Expect = 2e-23
Identities = 56/161 (34%), Positives = 96/161 (59%), Gaps = 5/161 (3%)
Frame = +3
Query: 24 IEARLSKLMLCGSTLRRVAEVFEKEIEAGLRQQ---PSSLQMENTYVPELPDGTEEGSFL 194
I+ L + L TL + F KE++ GL + ++++M T+V +PDG+E+G F+
Sbjct: 21 IDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFI 80
Query: 195 ALDLGGTNFRVLFLEL--KAGQLLREKVKHYHINDALRLGPGEDLFNFLADCVQDFLVSQ 368
ALDLGG++FR+L +++ + Q + + + Y + + G G LF+ +A+C+ DF+ +
Sbjct: 81 ALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKR 140
Query: 369 SMEKETFSLGFTFSFPMRQHSISSGELITWTKSFNCGGMDG 491
++ + +GFTFSFP +Q I LITWTK F G++G
Sbjct: 141 KIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEG 181
Score = 38.3 bits (85), Expect = 0.026
Identities = 19/59 (32%), Positives = 30/59 (50%), Gaps = 1/59 (1%)
Frame = +1
Query: 490 GFDVAALLQRCLSARS-LDVTVRVLLNDTTGTLVAGAHIDRNVGIXXDSGYRLNRCYME 663
G DV LL + + R D + ++NDT GT++ + D++ + G N CYME
Sbjct: 181 GADVVKLLNKAIKKRGDYDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYME 239
Score = 38.3 bits (85), Expect = 0.026
Identities = 21/64 (32%), Positives = 32/64 (50%), Gaps = 1/64 (1%)
Frame = +1
Query: 475 AAEWTGFDVAALLQRCLSARS-LDVTVRVLLNDTTGTLVAGAHIDRNVGIXXDSGYRLNR 651
A + G DV LL+ + R D+ V ++NDT GT++ A+ + + G N
Sbjct: 624 ATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNA 683
Query: 652 CYME 663
CYME
Sbjct: 684 CYME 687
>AF016365-2|AAF82320.1| 905|Homo sapiens hexokinase 1 isoform td
protein.
Length = 905
Score = 120 bits (290), Expect = 4e-27
Identities = 69/167 (41%), Positives = 99/167 (59%), Gaps = 8/167 (4%)
Frame = +3
Query: 18 QKIEARLSKLMLCGSTLRRVAEVFEKEIEAGLRQQPSS---LQMENTYVPELPDGTEEGS 188
++IE L+ L L V + E+E GLR+Q + ++M ++V PDGTE G
Sbjct: 456 RQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTENGD 515
Query: 189 FLALDLGGTNFRVLFLELKAGQLLREKV--KHYHINDALRLGPGEDLFNFLADCVQDFLV 362
FLALDLGGTNFRVL +++++G+ ++ K Y I + G GE+LF+ + C+ DFL
Sbjct: 516 FLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLD 575
Query: 363 SQSMEKETFSLGFTFSFPMRQHSISSGELITWTKSF---NCGGMDGV 494
++ LGFTFSFP +Q S+ +G LITWTK F +C G D V
Sbjct: 576 YMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVV 622
Score = 108 bits (259), Expect = 2e-23
Identities = 56/161 (34%), Positives = 96/161 (59%), Gaps = 5/161 (3%)
Frame = +3
Query: 24 IEARLSKLMLCGSTLRRVAEVFEKEIEAGLRQQ---PSSLQMENTYVPELPDGTEEGSFL 194
I+ L + L TL + F KE++ GL + ++++M T+V +PDG+E+G F+
Sbjct: 10 IDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFI 69
Query: 195 ALDLGGTNFRVLFLEL--KAGQLLREKVKHYHINDALRLGPGEDLFNFLADCVQDFLVSQ 368
ALDLGG++FR+L +++ + Q + + + Y + + G G LF+ +A+C+ DF+ +
Sbjct: 70 ALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKR 129
Query: 369 SMEKETFSLGFTFSFPMRQHSISSGELITWTKSFNCGGMDG 491
++ + +GFTFSFP +Q I LITWTK F G++G
Sbjct: 130 KIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEG 170
Score = 38.3 bits (85), Expect = 0.026
Identities = 19/59 (32%), Positives = 30/59 (50%), Gaps = 1/59 (1%)
Frame = +1
Query: 490 GFDVAALLQRCLSARS-LDVTVRVLLNDTTGTLVAGAHIDRNVGIXXDSGYRLNRCYME 663
G DV LL + + R D + ++NDT GT++ + D++ + G N CYME
Sbjct: 170 GADVVKLLNKAIKKRGDYDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYME 228
Score = 38.3 bits (85), Expect = 0.026
Identities = 21/64 (32%), Positives = 32/64 (50%), Gaps = 1/64 (1%)
Frame = +1
Query: 475 AAEWTGFDVAALLQRCLSARS-LDVTVRVLLNDTTGTLVAGAHIDRNVGIXXDSGYRLNR 651
A + G DV LL+ + R D+ V ++NDT GT++ A+ + + G N
Sbjct: 613 ATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNA 672
Query: 652 CYME 663
CYME
Sbjct: 673 CYME 676
>AF016365-1|AAF82319.1| 921|Homo sapiens hexokinase 1 isoform ta/tb
protein.
Length = 921
Score = 120 bits (290), Expect = 4e-27
Identities = 69/167 (41%), Positives = 99/167 (59%), Gaps = 8/167 (4%)
Frame = +3
Query: 18 QKIEARLSKLMLCGSTLRRVAEVFEKEIEAGLRQQPSS---LQMENTYVPELPDGTEEGS 188
++IE L+ L L V + E+E GLR+Q + ++M ++V PDGTE G
Sbjct: 472 RQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTENGD 531
Query: 189 FLALDLGGTNFRVLFLELKAGQLLREKV--KHYHINDALRLGPGEDLFNFLADCVQDFLV 362
FLALDLGGTNFRVL +++++G+ ++ K Y I + G GE+LF+ + C+ DFL
Sbjct: 532 FLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLD 591
Query: 363 SQSMEKETFSLGFTFSFPMRQHSISSGELITWTKSF---NCGGMDGV 494
++ LGFTFSFP +Q S+ +G LITWTK F +C G D V
Sbjct: 592 YMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVV 638
Score = 109 bits (262), Expect = 9e-24
Identities = 57/166 (34%), Positives = 98/166 (59%), Gaps = 5/166 (3%)
Frame = +3
Query: 9 LRAQKIEARLSKLMLCGSTLRRVAEVFEKEIEAGLRQQ---PSSLQMENTYVPELPDGTE 179
L +I+ L + L TL + F KE++ GL + ++++M T+V +PDG+E
Sbjct: 21 LAESEIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSE 80
Query: 180 EGSFLALDLGGTNFRVLFLEL--KAGQLLREKVKHYHINDALRLGPGEDLFNFLADCVQD 353
+G F+ALDLGG++FR+L +++ + Q + + + Y + + G G LF+ +A+C+ D
Sbjct: 81 KGDFIALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGD 140
Query: 354 FLVSQSMEKETFSLGFTFSFPMRQHSISSGELITWTKSFNCGGMDG 491
F+ + ++ + +GFTFSFP +Q I LITWTK F G++G
Sbjct: 141 FMEKRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEG 186
Score = 38.3 bits (85), Expect = 0.026
Identities = 19/59 (32%), Positives = 30/59 (50%), Gaps = 1/59 (1%)
Frame = +1
Query: 490 GFDVAALLQRCLSARS-LDVTVRVLLNDTTGTLVAGAHIDRNVGIXXDSGYRLNRCYME 663
G DV LL + + R D + ++NDT GT++ + D++ + G N CYME
Sbjct: 186 GADVVKLLNKAIKKRGDYDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYME 244
Score = 38.3 bits (85), Expect = 0.026
Identities = 21/64 (32%), Positives = 32/64 (50%), Gaps = 1/64 (1%)
Frame = +1
Query: 475 AAEWTGFDVAALLQRCLSARS-LDVTVRVLLNDTTGTLVAGAHIDRNVGIXXDSGYRLNR 651
A + G DV LL+ + R D+ V ++NDT GT++ A+ + + G N
Sbjct: 629 ATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNA 688
Query: 652 CYME 663
CYME
Sbjct: 689 CYME 692
>AB209526-1|BAD92763.1| 949|Homo sapiens hexokinase 1 isoform HKI
variant protein.
Length = 949
Score = 120 bits (290), Expect = 4e-27
Identities = 69/167 (41%), Positives = 99/167 (59%), Gaps = 8/167 (4%)
Frame = +3
Query: 18 QKIEARLSKLMLCGSTLRRVAEVFEKEIEAGLRQQPSS---LQMENTYVPELPDGTEEGS 188
++IE L+ L L V + E+E GLR+Q + ++M ++V PDGTE G
Sbjct: 500 RQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTENGD 559
Query: 189 FLALDLGGTNFRVLFLELKAGQLLREKV--KHYHINDALRLGPGEDLFNFLADCVQDFLV 362
FLALDLGGTNFRVL +++++G+ ++ K Y I + G GE+LF+ + C+ DFL
Sbjct: 560 FLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLD 619
Query: 363 SQSMEKETFSLGFTFSFPMRQHSISSGELITWTKSF---NCGGMDGV 494
++ LGFTFSFP +Q S+ +G LITWTK F +C G D V
Sbjct: 620 YMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVV 666
Score = 111 bits (266), Expect = 3e-24
Identities = 57/165 (34%), Positives = 99/165 (60%), Gaps = 5/165 (3%)
Frame = +3
Query: 12 RAQKIEARLSKLMLCGSTLRRVAEVFEKEIEAGLRQQ---PSSLQMENTYVPELPDGTEE 182
+ +KI+ L + L TL + F KE++ GL + ++++M T+V +PDG+E+
Sbjct: 50 QVKKIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEK 109
Query: 183 GSFLALDLGGTNFRVLFLEL--KAGQLLREKVKHYHINDALRLGPGEDLFNFLADCVQDF 356
G F+ALDLGG++FR+L +++ + Q + + + Y + + G G LF+ +A+C+ DF
Sbjct: 110 GDFIALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDF 169
Query: 357 LVSQSMEKETFSLGFTFSFPMRQHSISSGELITWTKSFNCGGMDG 491
+ + ++ + +GFTFSFP +Q I LITWTK F G++G
Sbjct: 170 MEKRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEG 214
Score = 38.3 bits (85), Expect = 0.026
Identities = 19/59 (32%), Positives = 30/59 (50%), Gaps = 1/59 (1%)
Frame = +1
Query: 490 GFDVAALLQRCLSARS-LDVTVRVLLNDTTGTLVAGAHIDRNVGIXXDSGYRLNRCYME 663
G DV LL + + R D + ++NDT GT++ + D++ + G N CYME
Sbjct: 214 GADVVKLLNKAIKKRGDYDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYME 272
Score = 38.3 bits (85), Expect = 0.026
Identities = 21/64 (32%), Positives = 32/64 (50%), Gaps = 1/64 (1%)
Frame = +1
Query: 475 AAEWTGFDVAALLQRCLSARS-LDVTVRVLLNDTTGTLVAGAHIDRNVGIXXDSGYRLNR 651
A + G DV LL+ + R D+ V ++NDT GT++ A+ + + G N
Sbjct: 657 ATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNA 716
Query: 652 CYME 663
CYME
Sbjct: 717 CYME 720
>BC021278-1|AAH21278.1| 427|Homo sapiens HKDC1 protein protein.
Length = 427
Score = 118 bits (285), Expect = 2e-26
Identities = 63/136 (46%), Positives = 86/136 (63%), Gaps = 4/136 (2%)
Frame = +3
Query: 96 EIEAGLRQQPSSL---QMENTYVPELPDGTEEGSFLALDLGGTNFRVLFLELKAGQL-LR 263
E+E GL+++ L +M TYV LPDGTE+G FLALDLGGTNFRVL +++++G+ +R
Sbjct: 4 ELEYGLKKKSHGLATVRMLPTYVCGLPDGTEKGKFLALDLGGTNFRVLLVKIRSGRRSVR 63
Query: 264 EKVKHYHINDALRLGPGEDLFNFLADCVQDFLVSQSMEKETFSLGFTFSFPMRQHSISSG 443
K + I + G GE+LF+ + C+ DFL ++ + LGFTFSFP RQ SI G
Sbjct: 64 MYNKIFAIPLEIMQGTGEELFDHIVQCIADFLDYMGLKGASLPLGFTFSFPCRQMSIDKG 123
Query: 444 ELITWTKSFNCGGMDG 491
LI WTK F +G
Sbjct: 124 TLIGWTKGFKATDCEG 139
Score = 40.3 bits (90), Expect = 0.006
Identities = 21/64 (32%), Positives = 34/64 (53%), Gaps = 1/64 (1%)
Frame = +1
Query: 475 AAEWTGFDVAALLQRCLSARS-LDVTVRVLLNDTTGTLVAGAHIDRNVGIXXDSGYRLNR 651
A + G DV +L+ + R+ D+ + ++NDT GT++ + D N I +G N
Sbjct: 134 ATDCEGEDVVDMLREAIKRRNEFDLDIVAVVNDTVGTMMTCGYEDPNCEIGLIAGTGSNM 193
Query: 652 CYME 663
CYME
Sbjct: 194 CYME 197
>AC104135-1|AAY24209.1| 573|Homo sapiens unknown protein.
Length = 573
Score = 115 bits (277), Expect = 1e-25
Identities = 63/157 (40%), Positives = 89/157 (56%), Gaps = 5/157 (3%)
Frame = +3
Query: 36 LSKLMLCGSTLRRVAEVFEKEIEAGLRQQPSS---LQMENTYVPELPDGTEEGSFLALDL 206
L L L L V + E+E GL ++ + ++M TYV PDGTE+G FLALDL
Sbjct: 130 LEHLQLSHDQLLEVKRRMKVEMERGLSKETHASAPVKMLPTYVCATPDGTEKGDFLALDL 189
Query: 207 GGTNFRVLFLELKAGQL--LREKVKHYHINDALRLGPGEDLFNFLADCVQDFLVSQSMEK 380
GGTNFRVL + ++ G+ + K Y I + G G++LF+ + C+ DFL M+
Sbjct: 190 GGTNFRVLLVRVRNGKWGGVEMHNKIYAIPQEVMHGTGDELFDHIVQCIADFLEYMGMKG 249
Query: 381 ETFSLGFTFSFPMRQHSISSGELITWTKSFNCGGMDG 491
+ LGFTFSFP +Q+S+ L+ WTK F G +G
Sbjct: 250 VSLPLGFTFSFPCQQNSLDESILLKWTKGFKASGCEG 286
Score = 35.5 bits (78), Expect = 0.18
Identities = 20/59 (33%), Positives = 29/59 (49%), Gaps = 1/59 (1%)
Frame = +1
Query: 490 GFDVAALLQRCLSARS-LDVTVRVLLNDTTGTLVAGAHIDRNVGIXXDSGYRLNRCYME 663
G DV LL+ + R D+ V ++NDT GT++ D + + G N CYME
Sbjct: 286 GEDVVTLLKEAIHRREEFDLDVVAVVNDTVGTMMTCGFEDPHCEVGLIVGTGSNACYME 344
>U42303-1|AAC50422.1| 566|Homo sapiens ATP:D-hexose
6-phosphotransferase protein.
Length = 566
Score = 108 bits (259), Expect = 2e-23
Identities = 60/164 (36%), Positives = 84/164 (51%), Gaps = 2/164 (1%)
Frame = +3
Query: 6 RLRAQK--IEARLSKLMLCGSTLRRVAEVFEKEIEAGLRQQPSSLQMENTYVPELPDGTE 179
RL A + +E L+ L L V K + G + SS +M T+V G+E
Sbjct: 118 RLAAHRRLLEETLAPFRLNHDQLAAVQAQMRKAMARGSEGESSSSRMLPTFVRATLTGSE 177
Query: 180 EGSFLALDLGGTNFRVLFLELKAGQLLREKVKHYHINDALRLGPGEDLFNFLADCVQDFL 359
G FLALDLGGTNFRVL + + G + ++ Y I + + G E LF+ + DC+ DF
Sbjct: 178 RGDFLALDLGGTNFRVLLVRVTTGVQITSEI--YSIPETVAQGSAEQLFDHIVDCIVDFQ 235
Query: 360 VSQSMEKETFSLGFTFSFPMRQHSISSGELITWTKSFNCGGMDG 491
Q + ++ GFTFSFP RQ + G L+ WTK F +G
Sbjct: 236 QKQGLSGQSLPTGFTFSFPCRQLGLDQGILLNWTKGFKASDCEG 279
Score = 40.3 bits (90), Expect = 0.006
Identities = 21/64 (32%), Positives = 37/64 (57%), Gaps = 1/64 (1%)
Frame = +1
Query: 475 AAEWTGFDVAALLQRCLSAR-SLDVTVRVLLNDTTGTLVAGAHIDRNVGIXXDSGYRLNR 651
A++ G DV +LL+ ++ R ++++ V ++NDT GT+++ + D I G N
Sbjct: 274 ASDCEGQDVVSLLREAITRRQAVELNVVAIVNDTVGTMMSCGYEDPRCEIGLIVGTGTNA 333
Query: 652 CYME 663
CYME
Sbjct: 334 CYME 337
>AL596223-8|CAH71505.1| 291|Homo sapiens hexokinase 1 protein.
Length = 291
Score = 108 bits (259), Expect = 2e-23
Identities = 56/161 (34%), Positives = 96/161 (59%), Gaps = 5/161 (3%)
Frame = +3
Query: 24 IEARLSKLMLCGSTLRRVAEVFEKEIEAGLRQQ---PSSLQMENTYVPELPDGTEEGSFL 194
I+ L + L TL + F KE++ GL + ++++M T+V +PDG+E+G F+
Sbjct: 21 IDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFI 80
Query: 195 ALDLGGTNFRVLFLEL--KAGQLLREKVKHYHINDALRLGPGEDLFNFLADCVQDFLVSQ 368
ALDLGG++FR+L +++ + Q + + + Y + + G G LF+ +A+C+ DF+ +
Sbjct: 81 ALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKR 140
Query: 369 SMEKETFSLGFTFSFPMRQHSISSGELITWTKSFNCGGMDG 491
++ + +GFTFSFP +Q I LITWTK F G++G
Sbjct: 141 KIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEG 181
Score = 38.3 bits (85), Expect = 0.026
Identities = 19/59 (32%), Positives = 30/59 (50%), Gaps = 1/59 (1%)
Frame = +1
Query: 490 GFDVAALLQRCLSARS-LDVTVRVLLNDTTGTLVAGAHIDRNVGIXXDSGYRLNRCYME 663
G DV LL + + R D + ++NDT GT++ + D++ + G N CYME
Sbjct: 181 GADVVKLLNKAIKKRGDYDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYME 239
>AL596223-5|CAH71502.1| 139|Homo sapiens hexokinase 1 protein.
Length = 139
Score = 64.9 bits (151), Expect = 3e-10
Identities = 37/118 (31%), Positives = 69/118 (58%), Gaps = 5/118 (4%)
Frame = +3
Query: 9 LRAQKIEARLSKLMLCGSTLRRVAEVFEKEIEAGLRQQ---PSSLQMENTYVPELPDGTE 179
L +I+ L + L TL + F KE++ GL + ++++M T+V +PDG+E
Sbjct: 21 LAESEIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSE 80
Query: 180 EGSFLALDLGGTNFRVLFLEL--KAGQLLREKVKHYHINDALRLGPGEDLFNFLADCV 347
+G F+ALDLGG++FR+L +++ + Q + + + Y + + G G LF+ +A+C+
Sbjct: 81 KGDFIALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECL 138
>AL596223-7|CAH71504.1| 114|Homo sapiens hexokinase 1 protein.
Length = 114
Score = 54.8 bits (126), Expect = 3e-07
Identities = 28/76 (36%), Positives = 49/76 (64%), Gaps = 3/76 (3%)
Frame = +3
Query: 24 IEARLSKLMLCGSTLRRVAEVFEKEIEAGLRQQ---PSSLQMENTYVPELPDGTEEGSFL 194
I+ L + L TL + F KE++ GL + ++++M T+V +PDG+E+G F+
Sbjct: 10 IDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFI 69
Query: 195 ALDLGGTNFRVLFLEL 242
ALDLGG++FR+L +++
Sbjct: 70 ALDLGGSSFRILRVQV 85
>AF073786-1|AAC25424.1| 114|Homo sapiens testis-specific hexokinase
1 protein.
Length = 114
Score = 54.8 bits (126), Expect = 3e-07
Identities = 28/76 (36%), Positives = 49/76 (64%), Gaps = 3/76 (3%)
Frame = +3
Query: 24 IEARLSKLMLCGSTLRRVAEVFEKEIEAGLRQQ---PSSLQMENTYVPELPDGTEEGSFL 194
I+ L + L TL + F KE++ GL + ++++M T+V +PDG+E+G F+
Sbjct: 10 IDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFI 69
Query: 195 ALDLGGTNFRVLFLEL 242
ALDLGG++FR+L +++
Sbjct: 70 ALDLGGSSFRILRVQV 85
>DQ871602-1|ABI49509.1| 127|Homo sapiens HK2 protein.
Length = 127
Score = 42.3 bits (95), Expect = 0.002
Identities = 21/59 (35%), Positives = 32/59 (54%), Gaps = 1/59 (1%)
Frame = +1
Query: 490 GFDVAALLQRCLSARS-LDVTVRVLLNDTTGTLVAGAHIDRNVGIXXDSGYRLNRCYME 663
G DV AL+++ + R D+ + ++NDT GT++ + D N I G N CYME
Sbjct: 17 GRDVVALIRKAIQRRGDFDIDIVAVVNDTVGTMMTCGYDDHNCEIGLIVGTGSNACYME 75
>D25412-1|BAA04999.1| 126|Homo sapiens type 2 hexokinase protein.
Length = 126
Score = 35.5 bits (78), Expect = 0.18
Identities = 20/59 (33%), Positives = 29/59 (49%), Gaps = 1/59 (1%)
Frame = +1
Query: 490 GFDVAALLQRCLSARS-LDVTVRVLLNDTTGTLVAGAHIDRNVGIXXDSGYRLNRCYME 663
G DV LL+ + R D+ V ++NDT GT++ D + + G N CYME
Sbjct: 17 GEDVVTLLKEAIHRREEFDLDVVAVVNDTVGTMMTCGFEDPHCEVGLIVGTGSNACYME 75
>BX538078-1|CAD98002.1| 160|Homo sapiens hypothetical protein
protein.
Length = 160
Score = 33.5 bits (73), Expect = 0.74
Identities = 15/41 (36%), Positives = 23/41 (56%)
Frame = +1
Query: 541 DVTVRVLLNDTTGTLVAGAHIDRNVGIXXDSGYRLNRCYME 663
D+ + ++NDT GT++ + D N I +G N CYME
Sbjct: 1 DLDIVAVVNDTVGTMMTCGYEDPNCEIGLIAGTGSNMCYME 41
>M34338-1|AAA36633.1| 302|Homo sapiens spermidine synthase protein.
Length = 302
Score = 30.3 bits (65), Expect = 6.9
Identities = 21/78 (26%), Positives = 35/78 (44%)
Frame = +3
Query: 222 RVLFLELKAGQLLREKVKHYHINDALRLGPGEDLFNFLADCVQDFLVSQSMEKETFSLGF 401
+VL + G +LRE VKH + ++ ED+ + + S K T +G
Sbjct: 96 KVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQVSKKFLPGMAIGYSSSKVTLHVGD 155
Query: 402 TFSFPMRQHSISSGELIT 455
F F M+Q+ + +IT
Sbjct: 156 GFEF-MKQNQDAFDVIIT 172
>M64231-1|AAA60574.1| 302|Homo sapiens spermidine synthase protein.
Length = 302
Score = 29.9 bits (64), Expect = 9.1
Identities = 21/78 (26%), Positives = 35/78 (44%)
Frame = +3
Query: 222 RVLFLELKAGQLLREKVKHYHINDALRLGPGEDLFNFLADCVQDFLVSQSMEKETFSLGF 401
+VL + G +LRE VKH + ++ ED+ + + S K T +G
Sbjct: 96 KVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQVSKKFLPGMAIGYSSSKLTLHVGD 155
Query: 402 TFSFPMRQHSISSGELIT 455
F F M+Q+ + +IT
Sbjct: 156 GFEF-MKQNQDAFDVIIT 172
>BC033106-1|AAH33106.1| 302|Homo sapiens spermidine synthase
protein.
Length = 302
Score = 29.9 bits (64), Expect = 9.1
Identities = 21/78 (26%), Positives = 35/78 (44%)
Frame = +3
Query: 222 RVLFLELKAGQLLREKVKHYHINDALRLGPGEDLFNFLADCVQDFLVSQSMEKETFSLGF 401
+VL + G +LRE VKH + ++ ED+ + + S K T +G
Sbjct: 96 KVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQVSKKFLPGMAIGYSSSKLTLHVGD 155
Query: 402 TFSFPMRQHSISSGELIT 455
F F M+Q+ + +IT
Sbjct: 156 GFEF-MKQNQDAFDVIIT 172
>BC000309-1|AAH00309.1| 302|Homo sapiens spermidine synthase
protein.
Length = 302
Score = 29.9 bits (64), Expect = 9.1
Identities = 21/78 (26%), Positives = 35/78 (44%)
Frame = +3
Query: 222 RVLFLELKAGQLLREKVKHYHINDALRLGPGEDLFNFLADCVQDFLVSQSMEKETFSLGF 401
+VL + G +LRE VKH + ++ ED+ + + S K T +G
Sbjct: 96 KVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQVSKKFLPGMAIGYSSSKLTLHVGD 155
Query: 402 TFSFPMRQHSISSGELIT 455
F F M+Q+ + +IT
Sbjct: 156 GFEF-MKQNQDAFDVIIT 172
>AL109811-6|CAI22104.1| 302|Homo sapiens spermidine synthase
protein.
Length = 302
Score = 29.9 bits (64), Expect = 9.1
Identities = 21/78 (26%), Positives = 35/78 (44%)
Frame = +3
Query: 222 RVLFLELKAGQLLREKVKHYHINDALRLGPGEDLFNFLADCVQDFLVSQSMEKETFSLGF 401
+VL + G +LRE VKH + ++ ED+ + + S K T +G
Sbjct: 96 KVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQVSKKFLPGMAIGYSSSKLTLHVGD 155
Query: 402 TFSFPMRQHSISSGELIT 455
F F M+Q+ + +IT
Sbjct: 156 GFEF-MKQNQDAFDVIIT 172
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 113,327,876
Number of Sequences: 237096
Number of extensions: 2693287
Number of successful extensions: 6675
Number of sequences better than 10.0: 48
Number of HSP's better than 10.0 without gapping: 6191
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6609
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8063224416
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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