Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= brP-1460
(800 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U84401-1|AAB41788.1| 787|Homo sapiens smoothened protein. 86 2e-16
BC009989-1|AAH09989.1| 787|Homo sapiens smoothened homolog (Dro... 86 2e-16
AF120103-1|AAF31757.1| 787|Homo sapiens Gx protein protein. 86 2e-16
AF114821-1|AAD17202.1| 787|Homo sapiens smoothened protein. 86 2e-16
AF071494-1|AAC24863.1| 787|Homo sapiens Gx protein protein. 86 2e-16
AL121749-3|CAC10185.1| 694|Homo sapiens frizzled homolog 8 (Dro... 48 3e-05
AB043703-1|BAB41064.1| 694|Homo sapiens seven-transmembrane rec... 48 3e-05
U82169-1|AAC51174.1| 591|Homo sapiens frizzled homolog protein. 46 2e-04
BC074998-1|AAH74998.1| 581|Homo sapiens frizzled 10 protein. 46 2e-04
BC074997-1|AAH74997.1| 581|Homo sapiens frizzled homolog 10 (Dr... 46 2e-04
BC070037-1|AAH70037.1| 581|Homo sapiens frizzled homolog 10 (Dr... 46 2e-04
AC005049-1|AAQ93359.1| 591|Homo sapiens unknown protein. 46 2e-04
AB027464-1|BAA84093.1| 581|Homo sapiens Frizzled-10 protein. 46 2e-04
BC026333-1|AAH26333.1| 591|Homo sapiens frizzled homolog 9 (Dro... 46 2e-04
U43318-1|AAC50385.1| 585|Homo sapiens transmembrane receptor pr... 39 0.024
AC096772-3|AAY24058.1| 585|Homo sapiens unknown protein. 39 0.024
AB043702-1|BAB60959.1| 585|Homo sapiens seven-transmembrane rec... 39 0.024
BC051271-1|AAH51271.1| 647|Homo sapiens frizzled homolog 1 (Dro... 35 0.39
AF072872-1|AAD41636.1| 648|Homo sapiens frizzled 1 protein. 35 0.39
AC084381-1|AAS02008.1| 647|Homo sapiens unknown protein. 35 0.39
AB017363-1|BAA34666.1| 647|Homo sapiens frizzled-1 protein. 35 0.39
L37882-1|AAB46397.1| 565|Homo sapiens frizzled protein. 33 1.2
BC113404-1|AAI13405.1| 565|Homo sapiens FZD2 protein protein. 33 1.2
BC113402-1|AAI13403.1| 565|Homo sapiens FZD2 protein protein. 33 1.2
BC052266-1|AAH52266.1| 641|Homo sapiens FZD2 protein protein. 33 1.2
AB017364-1|BAA34667.1| 565|Homo sapiens frizzled-2 protein. 33 1.2
BC015915-1|AAH15915.1| 574|Homo sapiens frizzled homolog 7 (Dro... 32 2.1
AC069148-1|AAX93250.1| 574|Homo sapiens unknown protein. 32 2.1
AB017365-1|BAA34668.1| 574|Homo sapiens frizzled-7 protein. 32 2.1
AF167585-1|AAF15419.1| 78|Homo sapiens immunoglobulin heavy ch... 31 4.8
AB010881-1|BAA32424.1| 574|Homo sapiens FzE3 protein. 31 6.4
>U84401-1|AAB41788.1| 787|Homo sapiens smoothened protein.
Length = 787
Score = 85.8 bits (203), Expect = 2e-16
Identities = 46/155 (29%), Positives = 79/155 (50%), Gaps = 5/155 (3%)
Frame = +1
Query: 4 FFLLRGVFSLVVVRVSSKDVISPRASNKIRRTITRCSITAALVAVFICVTFACHIYEFRN 183
+FL+RGV +L ++ + ++S +A++KI T+ R I L F+ +TF+CH Y+F N
Sbjct: 417 YFLIRGVMTLFSIKSNHPGLLSEKAASKINETMLRLGIFGFLAFGFVLITFSCHFYDFFN 476
Query: 184 ADLWKDSFKRNIICRLEA-----GQERQKECLTGSRPSISVLQLRLLCCFAAGALMSSWT 348
W+ SF+ ++C+ ++ +C +RPS+ V ++ L F G MS+W
Sbjct: 477 QAEWERSFRDYVLCQANVTIGLPTKQPIPDCEIKNRPSLLVEKINLFAMFGTGIAMSTWV 536
Query: 349 WTPXXXXXXXXXXXXKCGCSVDEEITRRAQKHELI 453
WT G S DE +R +K ++I
Sbjct: 537 WTKATLLIWRRTWCRLTGQSDDE--PKRIKKSKMI 569
>BC009989-1|AAH09989.1| 787|Homo sapiens smoothened homolog
(Drosophila) protein.
Length = 787
Score = 85.8 bits (203), Expect = 2e-16
Identities = 46/155 (29%), Positives = 79/155 (50%), Gaps = 5/155 (3%)
Frame = +1
Query: 4 FFLLRGVFSLVVVRVSSKDVISPRASNKIRRTITRCSITAALVAVFICVTFACHIYEFRN 183
+FL+RGV +L ++ + ++S +A++KI T+ R I L F+ +TF+CH Y+F N
Sbjct: 417 YFLIRGVMTLFSIKSNHPGLLSEKAASKINETMLRLGIFGFLAFGFVLITFSCHFYDFFN 476
Query: 184 ADLWKDSFKRNIICRLEA-----GQERQKECLTGSRPSISVLQLRLLCCFAAGALMSSWT 348
W+ SF+ ++C+ ++ +C +RPS+ V ++ L F G MS+W
Sbjct: 477 QAEWERSFRDYVLCQANVTIGLPTKQPIPDCEIKNRPSLLVEKINLFAMFGTGIAMSTWV 536
Query: 349 WTPXXXXXXXXXXXXKCGCSVDEEITRRAQKHELI 453
WT G S DE +R +K ++I
Sbjct: 537 WTKATLLIWRRTWCRLTGQSDDE--PKRIKKSKMI 569
>AF120103-1|AAF31757.1| 787|Homo sapiens Gx protein protein.
Length = 787
Score = 85.8 bits (203), Expect = 2e-16
Identities = 46/155 (29%), Positives = 79/155 (50%), Gaps = 5/155 (3%)
Frame = +1
Query: 4 FFLLRGVFSLVVVRVSSKDVISPRASNKIRRTITRCSITAALVAVFICVTFACHIYEFRN 183
+FL+RGV +L ++ + ++S +A++KI T+ R I L F+ +TF+CH Y+F N
Sbjct: 417 YFLIRGVMTLFSIKSNHPGLLSEKAASKINETMLRLGIFGFLAFGFVLITFSCHFYDFFN 476
Query: 184 ADLWKDSFKRNIICRLEA-----GQERQKECLTGSRPSISVLQLRLLCCFAAGALMSSWT 348
W+ SF+ ++C+ ++ +C +RPS+ V ++ L F G MS+W
Sbjct: 477 QAEWERSFRDYVLCQANVTIGLPTKQPIPDCEIKNRPSLLVEKINLFAMFGTGIAMSTWV 536
Query: 349 WTPXXXXXXXXXXXXKCGCSVDEEITRRAQKHELI 453
WT G S DE +R +K ++I
Sbjct: 537 WTKATLLIWRRTWCRLTGQSDDE--PKRIKKSKMI 569
>AF114821-1|AAD17202.1| 787|Homo sapiens smoothened protein.
Length = 787
Score = 85.8 bits (203), Expect = 2e-16
Identities = 46/155 (29%), Positives = 79/155 (50%), Gaps = 5/155 (3%)
Frame = +1
Query: 4 FFLLRGVFSLVVVRVSSKDVISPRASNKIRRTITRCSITAALVAVFICVTFACHIYEFRN 183
+FL+RGV +L ++ + ++S +A++KI T+ R I L F+ +TF+CH Y+F N
Sbjct: 417 YFLIRGVMTLFSIKSNHPGLLSEKAASKINETMLRLGIFGFLAFGFVLITFSCHFYDFFN 476
Query: 184 ADLWKDSFKRNIICRLEA-----GQERQKECLTGSRPSISVLQLRLLCCFAAGALMSSWT 348
W+ SF+ ++C+ ++ +C +RPS+ V ++ L F G MS+W
Sbjct: 477 QAEWERSFRDYVLCQANVTIGLPTKQPIPDCEIKNRPSLLVEKINLFAMFGTGIAMSTWV 536
Query: 349 WTPXXXXXXXXXXXXKCGCSVDEEITRRAQKHELI 453
WT G S DE +R +K ++I
Sbjct: 537 WTKATLLIWRRTWCRLTGQSDDE--PKRIKKSKMI 569
>AF071494-1|AAC24863.1| 787|Homo sapiens Gx protein protein.
Length = 787
Score = 85.8 bits (203), Expect = 2e-16
Identities = 46/155 (29%), Positives = 79/155 (50%), Gaps = 5/155 (3%)
Frame = +1
Query: 4 FFLLRGVFSLVVVRVSSKDVISPRASNKIRRTITRCSITAALVAVFICVTFACHIYEFRN 183
+FL+RGV +L ++ + ++S +A++KI T+ R I L F+ +TF+CH Y+F N
Sbjct: 417 YFLIRGVMTLFSIKSNHPGLLSEKAASKINETMLRLGIFGFLAFGFVLITFSCHFYDFFN 476
Query: 184 ADLWKDSFKRNIICRLEA-----GQERQKECLTGSRPSISVLQLRLLCCFAAGALMSSWT 348
W+ SF+ ++C+ ++ +C +RPS+ V ++ L F G MS+W
Sbjct: 477 QAEWERSFRDYVLCQANVTIGLPTKQPIPDCEIKNRPSLLVEKINLFAMFGTGIAMSTWV 536
Query: 349 WTPXXXXXXXXXXXXKCGCSVDEEITRRAQKHELI 453
WT G S DE +R +K ++I
Sbjct: 537 WTKATLLIWRRTWCRLTGQSDDE--PKRIKKSKMI 569
>AL121749-3|CAC10185.1| 694|Homo sapiens frizzled homolog 8
(Drosophila) protein.
Length = 694
Score = 48.4 bits (110), Expect = 3e-05
Identities = 31/116 (26%), Positives = 45/116 (38%)
Frame = +1
Query: 7 FLLRGVFSLVVVRVSSKDVISPRASNKIRRTITRCSITAALVAVFICVTFACHIYEFRNA 186
FLL G SL +R K P ++K+ + + R + L V V AC YE N
Sbjct: 499 FLLAGFVSLFRIRSVIKQQDGPTKTHKLEKLMIRLGLFTVLYTVPAAVVVACLFYEQHNR 558
Query: 187 DLWKDSFKRNIICRLEAGQERQKECLTGSRPSISVLQLRLLCCFAAGALMSSWTWT 354
W+ + + L+ Q R RP +V L+ C G W W+
Sbjct: 559 PRWEATHNCPCLRDLQPDQAR--------RPDYAVFMLKYFMCLVVGITSGVWVWS 606
>AB043703-1|BAB41064.1| 694|Homo sapiens seven-transmembrane
receptor Frizzled-8 protein.
Length = 694
Score = 48.4 bits (110), Expect = 3e-05
Identities = 31/116 (26%), Positives = 45/116 (38%)
Frame = +1
Query: 7 FLLRGVFSLVVVRVSSKDVISPRASNKIRRTITRCSITAALVAVFICVTFACHIYEFRNA 186
FLL G SL +R K P ++K+ + + R + L V V AC YE N
Sbjct: 499 FLLAGFVSLFRIRSVIKQQDGPTKTHKLEKLMIRLGLFTVLYTVPAAVVVACLFYEQHNR 558
Query: 187 DLWKDSFKRNIICRLEAGQERQKECLTGSRPSISVLQLRLLCCFAAGALMSSWTWT 354
W+ + + L+ Q R RP +V L+ C G W W+
Sbjct: 559 PRWEATHNCPCLRDLQPDQAR--------RPDYAVFMLKYFMCLVVGITSGVWVWS 606
>U82169-1|AAC51174.1| 591|Homo sapiens frizzled homolog protein.
Length = 591
Score = 46.0 bits (104), Expect = 2e-04
Identities = 28/118 (23%), Positives = 49/118 (41%), Gaps = 2/118 (1%)
Frame = +1
Query: 7 FLLRGVFSLVVVRVSSKDVISPRASNKIRRTITRCSITAALVAVFICVTFACHIYEFRNA 186
FLL G +L +R K + K+ + + + + + L V C++YE N
Sbjct: 416 FLLTGFVALFHIRKIMKT--GGTNTEKLEKLMVKIGVFSILYTVPATCVIVCYVYERLNM 473
Query: 187 DLWKDSFKRNIICRLEAGQERQKECLT--GSRPSISVLQLRLLCCFAAGALMSSWTWT 354
D W+ C AG +++C GS P+++V L++ G W W+
Sbjct: 474 DFWRLRATEQ-PCAAAAGPGGRRDCSLPGGSVPTVAVFMLKIFMSLVVGITSGVWVWS 530
>BC074998-1|AAH74998.1| 581|Homo sapiens frizzled 10 protein.
Length = 581
Score = 46.0 bits (104), Expect = 2e-04
Identities = 28/117 (23%), Positives = 51/117 (43%), Gaps = 1/117 (0%)
Frame = +1
Query: 7 FLLRGVFSLVVVRVSSKDVISPRASNKIRRTITRCSITAALVAVFICVTFACHIYEFRNA 186
F+L G +L +R K ++K+ + + R + + L V AC+ YE N
Sbjct: 412 FILSGFVALFHIRRVMKT--GGENTDKLEKLMVRIGLFSVLYTVPATCVIACYFYERLNM 469
Query: 187 DLWKDSFKRNIICRLEAGQERQKECL-TGSRPSISVLQLRLLCCFAAGALMSSWTWT 354
D WK ++ C++ Q + +CL S P++ + +++ G W WT
Sbjct: 470 DYWKILAAQH-KCKMN-NQTKTLDCLMAASIPAVEIFMVKIFMLLVVGITSGMWIWT 524
>BC074997-1|AAH74997.1| 581|Homo sapiens frizzled homolog 10
(Drosophila) protein.
Length = 581
Score = 46.0 bits (104), Expect = 2e-04
Identities = 28/117 (23%), Positives = 51/117 (43%), Gaps = 1/117 (0%)
Frame = +1
Query: 7 FLLRGVFSLVVVRVSSKDVISPRASNKIRRTITRCSITAALVAVFICVTFACHIYEFRNA 186
F+L G +L +R K ++K+ + + R + + L V AC+ YE N
Sbjct: 412 FILSGFVALFHIRRVMKT--GGENTDKLEKLMVRIGLFSVLYTVPATCVIACYFYERLNM 469
Query: 187 DLWKDSFKRNIICRLEAGQERQKECL-TGSRPSISVLQLRLLCCFAAGALMSSWTWT 354
D WK ++ C++ Q + +CL S P++ + +++ G W WT
Sbjct: 470 DYWKILAAQH-KCKMN-NQTKTLDCLMAASIPAVEIFMVKIFMLLVVGITSGMWIWT 524
>BC070037-1|AAH70037.1| 581|Homo sapiens frizzled homolog 10
(Drosophila) protein.
Length = 581
Score = 46.0 bits (104), Expect = 2e-04
Identities = 28/117 (23%), Positives = 51/117 (43%), Gaps = 1/117 (0%)
Frame = +1
Query: 7 FLLRGVFSLVVVRVSSKDVISPRASNKIRRTITRCSITAALVAVFICVTFACHIYEFRNA 186
F+L G +L +R K ++K+ + + R + + L V AC+ YE N
Sbjct: 412 FILSGFVALFHIRRVMKT--GGENTDKLEKLMVRIGLFSVLYTVPATCVIACYFYERLNM 469
Query: 187 DLWKDSFKRNIICRLEAGQERQKECL-TGSRPSISVLQLRLLCCFAAGALMSSWTWT 354
D WK ++ C++ Q + +CL S P++ + +++ G W WT
Sbjct: 470 DYWKILAAQH-KCKMN-NQTKTLDCLMAASIPAVEIFMVKIFMLLVVGITSGMWIWT 524
>AC005049-1|AAQ93359.1| 591|Homo sapiens unknown protein.
Length = 591
Score = 46.0 bits (104), Expect = 2e-04
Identities = 28/118 (23%), Positives = 49/118 (41%), Gaps = 2/118 (1%)
Frame = +1
Query: 7 FLLRGVFSLVVVRVSSKDVISPRASNKIRRTITRCSITAALVAVFICVTFACHIYEFRNA 186
FLL G +L +R K + K+ + + + + + L V C++YE N
Sbjct: 416 FLLTGFVALFHIRKIMKT--GGTNTEKLEKLMVKIGVFSILYTVPATCVIVCYVYERLNM 473
Query: 187 DLWKDSFKRNIICRLEAGQERQKECLT--GSRPSISVLQLRLLCCFAAGALMSSWTWT 354
D W+ C AG +++C GS P+++V L++ G W W+
Sbjct: 474 DFWRLRATEQ-PCAAAAGPGGRRDCSLPGGSVPTVAVFMLKIFMSLVVGITSGVWVWS 530
>AB027464-1|BAA84093.1| 581|Homo sapiens Frizzled-10 protein.
Length = 581
Score = 46.0 bits (104), Expect = 2e-04
Identities = 28/117 (23%), Positives = 51/117 (43%), Gaps = 1/117 (0%)
Frame = +1
Query: 7 FLLRGVFSLVVVRVSSKDVISPRASNKIRRTITRCSITAALVAVFICVTFACHIYEFRNA 186
F+L G +L +R K ++K+ + + R + + L V AC+ YE N
Sbjct: 412 FILSGFVALFHIRRVMKT--GGENTDKLEKLMVRIGLFSVLYTVPATCVIACYFYERLNM 469
Query: 187 DLWKDSFKRNIICRLEAGQERQKECL-TGSRPSISVLQLRLLCCFAAGALMSSWTWT 354
D WK ++ C++ Q + +CL S P++ + +++ G W WT
Sbjct: 470 DYWKILAAQH-KCKMN-NQTKTLDCLMAASIPAVEIFMVKIFMLLVVGITSGMWIWT 524
>BC026333-1|AAH26333.1| 591|Homo sapiens frizzled homolog 9
(Drosophila) protein.
Length = 591
Score = 45.6 bits (103), Expect = 2e-04
Identities = 28/118 (23%), Positives = 49/118 (41%), Gaps = 2/118 (1%)
Frame = +1
Query: 7 FLLRGVFSLVVVRVSSKDVISPRASNKIRRTITRCSITAALVAVFICVTFACHIYEFRNA 186
FLL G +L +R K + K+ + + + + + L V C++YE N
Sbjct: 416 FLLTGFVALFHIRKIMKT--GGTNTEKLEKLMVKVGVFSILYTVPATCVIVCYVYERLNM 473
Query: 187 DLWKDSFKRNIICRLEAGQERQKECLT--GSRPSISVLQLRLLCCFAAGALMSSWTWT 354
D W+ C AG +++C GS P+++V L++ G W W+
Sbjct: 474 DFWRLRATEQ-PCAAAAGPGGRRDCSLPGGSVPTVAVFMLKIFMSLVVGITNGVWVWS 530
>U43318-1|AAC50385.1| 585|Homo sapiens transmembrane receptor
protein.
Length = 585
Score = 38.7 bits (86), Expect = 0.024
Identities = 28/116 (24%), Positives = 47/116 (40%)
Frame = +1
Query: 7 FLLRGVFSLVVVRVSSKDVISPRASNKIRRTITRCSITAALVAVFICVTFACHIYEFRNA 186
FLL G SL +R K ++K+ + + R I L V + AC++YE
Sbjct: 418 FLLAGFVSLFRIRSVIKQ--GGTKTDKLEKLMIRIGIFTLLYTVPASIVVACYLYE---- 471
Query: 187 DLWKDSFKRNIICRLEAGQERQKECLTGSRPSISVLQLRLLCCFAAGALMSSWTWT 354
+++S++ + C Q ++P VL L+ C G W W+
Sbjct: 472 QHYRESWEAALTCACPGHDTGQPR----AKPEYWVLMLKYFMCLVVGITSGVWIWS 523
>AC096772-3|AAY24058.1| 585|Homo sapiens unknown protein.
Length = 585
Score = 38.7 bits (86), Expect = 0.024
Identities = 28/116 (24%), Positives = 47/116 (40%)
Frame = +1
Query: 7 FLLRGVFSLVVVRVSSKDVISPRASNKIRRTITRCSITAALVAVFICVTFACHIYEFRNA 186
FLL G SL +R K ++K+ + + R I L V + AC++YE
Sbjct: 418 FLLAGFVSLFRIRSVIKQ--GGTKTDKLEKLMIRIGIFTLLYTVPASIVVACYLYE---- 471
Query: 187 DLWKDSFKRNIICRLEAGQERQKECLTGSRPSISVLQLRLLCCFAAGALMSSWTWT 354
+++S++ + C Q ++P VL L+ C G W W+
Sbjct: 472 QHYRESWEAALTCACPGHDTGQPR----AKPEYWVLMLKYFMCLVVGITSGVWIWS 523
>AB043702-1|BAB60959.1| 585|Homo sapiens seven-transmembrane
receptor Frizzled-5 protein.
Length = 585
Score = 38.7 bits (86), Expect = 0.024
Identities = 28/116 (24%), Positives = 47/116 (40%)
Frame = +1
Query: 7 FLLRGVFSLVVVRVSSKDVISPRASNKIRRTITRCSITAALVAVFICVTFACHIYEFRNA 186
FLL G SL +R K ++K+ + + R I L V + AC++YE
Sbjct: 418 FLLAGFVSLFRIRSVIKQ--GGTKTDKLEKLMIRIGIFTLLYTVPASIVVACYLYE---- 471
Query: 187 DLWKDSFKRNIICRLEAGQERQKECLTGSRPSISVLQLRLLCCFAAGALMSSWTWT 354
+++S++ + C Q ++P VL L+ C G W W+
Sbjct: 472 QHYRESWEAALTCACPGHDTGQPR----AKPEYWVLMLKYFMCLVVGITSGVWIWS 523
>BC051271-1|AAH51271.1| 647|Homo sapiens frizzled homolog 1
(Drosophila) protein.
Length = 647
Score = 34.7 bits (76), Expect = 0.39
Identities = 30/123 (24%), Positives = 46/123 (37%), Gaps = 7/123 (5%)
Frame = +1
Query: 7 FLLRGVFSLVVVRVSSKDVISPRASNKIRRTITRCSITAALVAVFICVTFACHIYEFRNA 186
FLL G SL +R K + K+ + + R + + L V + AC+ YE
Sbjct: 505 FLLAGFVSLFRIRTIMKH--DGTKTEKLEKLMVRIGVFSVLYTVPATIVIACYFYEQAFR 562
Query: 187 DLWKDSFKRN------IIC-RLEAGQERQKECLTGSRPSISVLQLRLLCCFAAGALMSSW 345
D W+ S+ I C L+AG P +V ++ L G W
Sbjct: 563 DQWERSWVAQSCKSYAIPCPHLQAGGGAPPH--PPMSPDFTVFMIKYLMTLIVGITSGFW 620
Query: 346 TWT 354
W+
Sbjct: 621 IWS 623
>AF072872-1|AAD41636.1| 648|Homo sapiens frizzled 1 protein.
Length = 648
Score = 34.7 bits (76), Expect = 0.39
Identities = 30/123 (24%), Positives = 46/123 (37%), Gaps = 7/123 (5%)
Frame = +1
Query: 7 FLLRGVFSLVVVRVSSKDVISPRASNKIRRTITRCSITAALVAVFICVTFACHIYEFRNA 186
FLL G SL +R K + K+ + + R + + L V + AC+ YE
Sbjct: 506 FLLAGFVSLFRIRTIMKH--DGTKTEKLEKLMVRIGVFSVLYTVPATIVIACYFYEQAFR 563
Query: 187 DLWKDSFKRN------IIC-RLEAGQERQKECLTGSRPSISVLQLRLLCCFAAGALMSSW 345
D W+ S+ I C L+AG P +V ++ L G W
Sbjct: 564 DQWERSWVAQSCKSYAIPCPHLQAGGGAPPH--PPMSPDFTVFMIKYLMTLIVGITSGFW 621
Query: 346 TWT 354
W+
Sbjct: 622 IWS 624
>AC084381-1|AAS02008.1| 647|Homo sapiens unknown protein.
Length = 647
Score = 34.7 bits (76), Expect = 0.39
Identities = 30/123 (24%), Positives = 46/123 (37%), Gaps = 7/123 (5%)
Frame = +1
Query: 7 FLLRGVFSLVVVRVSSKDVISPRASNKIRRTITRCSITAALVAVFICVTFACHIYEFRNA 186
FLL G SL +R K + K+ + + R + + L V + AC+ YE
Sbjct: 505 FLLAGFVSLFRIRTIMKH--DGTKTEKLEKLMVRIGVFSVLYTVPATIVIACYFYEQAFR 562
Query: 187 DLWKDSFKRN------IIC-RLEAGQERQKECLTGSRPSISVLQLRLLCCFAAGALMSSW 345
D W+ S+ I C L+AG P +V ++ L G W
Sbjct: 563 DQWERSWVAQSCKSYAIPCPHLQAGGGAPPH--PPMSPDFTVFMIKYLMTLIVGITSGFW 620
Query: 346 TWT 354
W+
Sbjct: 621 IWS 623
>AB017363-1|BAA34666.1| 647|Homo sapiens frizzled-1 protein.
Length = 647
Score = 34.7 bits (76), Expect = 0.39
Identities = 30/123 (24%), Positives = 46/123 (37%), Gaps = 7/123 (5%)
Frame = +1
Query: 7 FLLRGVFSLVVVRVSSKDVISPRASNKIRRTITRCSITAALVAVFICVTFACHIYEFRNA 186
FLL G SL +R K + K+ + + R + + L V + AC+ YE
Sbjct: 505 FLLAGFVSLFRIRTIMKH--DGTKTEKLEKLMVRIGVFSVLYTVPATIVIACYFYEQAFR 562
Query: 187 DLWKDSFKRN------IIC-RLEAGQERQKECLTGSRPSISVLQLRLLCCFAAGALMSSW 345
D W+ S+ I C L+AG P +V ++ L G W
Sbjct: 563 DQWERSWVAQSCKSYAIPCPHLQAGGGAPPH--PPMSPDFTVFMIKYLMTLIVGITSGFW 620
Query: 346 TWT 354
W+
Sbjct: 621 IWS 623
>L37882-1|AAB46397.1| 565|Homo sapiens frizzled protein.
Length = 565
Score = 33.1 bits (72), Expect = 1.2
Identities = 26/116 (22%), Positives = 42/116 (36%)
Frame = +1
Query: 7 FLLRGVFSLVVVRVSSKDVISPRASNKIRRTITRCSITAALVAVFICVTFACHIYEFRNA 186
FLL G SL +R K + K+ R + R + + L V + AC+ YE
Sbjct: 430 FLLAGFVSLFRIRTIMKH--DGTKTEKLERLMVRIGVFSVLYTVPATIVIACYFYEQAFR 487
Query: 187 DLWKDSFKRNIICRLEAGQERQKECLTGSRPSISVLQLRLLCCFAAGALMSSWTWT 354
+ W+ S+ C+ P +V ++ L G W W+
Sbjct: 488 EHWERSWVSQ-HCK-SLAIPCPAHYTPRMSPDFTVYMIKYLMTLIVGITSGFWIWS 541
>BC113404-1|AAI13405.1| 565|Homo sapiens FZD2 protein protein.
Length = 565
Score = 33.1 bits (72), Expect = 1.2
Identities = 26/116 (22%), Positives = 42/116 (36%)
Frame = +1
Query: 7 FLLRGVFSLVVVRVSSKDVISPRASNKIRRTITRCSITAALVAVFICVTFACHIYEFRNA 186
FLL G SL +R K + K+ R + R + + L V + AC+ YE
Sbjct: 430 FLLAGFVSLFRIRTIMKH--DGTKTEKLERLMVRIGVFSVLYTVPATIVIACYFYEQAFR 487
Query: 187 DLWKDSFKRNIICRLEAGQERQKECLTGSRPSISVLQLRLLCCFAAGALMSSWTWT 354
+ W+ S+ C+ P +V ++ L G W W+
Sbjct: 488 EHWERSWVSQ-HCK-SLAIPCPAHYTPRMSPDFTVYMIKYLMTLIVGITSGFWIWS 541
>BC113402-1|AAI13403.1| 565|Homo sapiens FZD2 protein protein.
Length = 565
Score = 33.1 bits (72), Expect = 1.2
Identities = 26/116 (22%), Positives = 42/116 (36%)
Frame = +1
Query: 7 FLLRGVFSLVVVRVSSKDVISPRASNKIRRTITRCSITAALVAVFICVTFACHIYEFRNA 186
FLL G SL +R K + K+ R + R + + L V + AC+ YE
Sbjct: 430 FLLAGFVSLFRIRTIMKH--DGTKTEKLERLMVRIGVFSVLYTVPATIVIACYFYEQAFR 487
Query: 187 DLWKDSFKRNIICRLEAGQERQKECLTGSRPSISVLQLRLLCCFAAGALMSSWTWT 354
+ W+ S+ C+ P +V ++ L G W W+
Sbjct: 488 EHWERSWVSQ-HCK-SLAIPCPAHYTPRMSPDFTVYMIKYLMTLIVGITSGFWIWS 541
>BC052266-1|AAH52266.1| 641|Homo sapiens FZD2 protein protein.
Length = 641
Score = 33.1 bits (72), Expect = 1.2
Identities = 26/116 (22%), Positives = 42/116 (36%)
Frame = +1
Query: 7 FLLRGVFSLVVVRVSSKDVISPRASNKIRRTITRCSITAALVAVFICVTFACHIYEFRNA 186
FLL G SL +R K + K+ R + R + + L V + AC+ YE
Sbjct: 506 FLLAGFVSLFRIRTIMKH--DGTKTEKLERLMVRIGVFSVLYTVPATIVIACYFYEQAFR 563
Query: 187 DLWKDSFKRNIICRLEAGQERQKECLTGSRPSISVLQLRLLCCFAAGALMSSWTWT 354
+ W+ S+ C+ P +V ++ L G W W+
Sbjct: 564 EHWERSWVSQ-HCK-SLAIPCPAHYTPRMSPDFTVYMIKYLMTLIVGITSGFWIWS 617
>AB017364-1|BAA34667.1| 565|Homo sapiens frizzled-2 protein.
Length = 565
Score = 33.1 bits (72), Expect = 1.2
Identities = 26/116 (22%), Positives = 42/116 (36%)
Frame = +1
Query: 7 FLLRGVFSLVVVRVSSKDVISPRASNKIRRTITRCSITAALVAVFICVTFACHIYEFRNA 186
FLL G SL +R K + K+ R + R + + L V + AC+ YE
Sbjct: 430 FLLAGFVSLFRIRTIMKH--DGTKTEKLERLMVRIGVFSVLYTVPATIVIACYFYEQAFR 487
Query: 187 DLWKDSFKRNIICRLEAGQERQKECLTGSRPSISVLQLRLLCCFAAGALMSSWTWT 354
+ W+ S+ C+ P +V ++ L G W W+
Sbjct: 488 EHWERSWVSQ-HCK-SLAIPCPAHYTPRMSPDFTVYMIKYLMTLIVGITSGFWIWS 541
>BC015915-1|AAH15915.1| 574|Homo sapiens frizzled homolog 7
(Drosophila) protein.
Length = 574
Score = 32.3 bits (70), Expect = 2.1
Identities = 27/120 (22%), Positives = 46/120 (38%), Gaps = 4/120 (3%)
Frame = +1
Query: 7 FLLRGVFSLVVVRVSSKDVISPRASNKIRRTITRCSITAALVAVFICVTFACHIYEFRNA 186
FLL G SL +R K + K+ + + R + + L V + AC+ YE
Sbjct: 439 FLLAGFVSLFRIRTIMKH--DGTKTEKLEKLMVRIGVFSVLYTVPATIVLACYFYEQAFR 496
Query: 187 DLWKDSFKRNIICRLEAGQERQKECLTGSRPSIS----VLQLRLLCCFAAGALMSSWTWT 354
+ W+ ++ L+ + C G P +S V ++ L G W W+
Sbjct: 497 EHWERTW------LLQTCKSYAVPCPPGHFPPMSPDFTVFMIKYLMTMIVGITTGFWIWS 550
>AC069148-1|AAX93250.1| 574|Homo sapiens unknown protein.
Length = 574
Score = 32.3 bits (70), Expect = 2.1
Identities = 27/120 (22%), Positives = 46/120 (38%), Gaps = 4/120 (3%)
Frame = +1
Query: 7 FLLRGVFSLVVVRVSSKDVISPRASNKIRRTITRCSITAALVAVFICVTFACHIYEFRNA 186
FLL G SL +R K + K+ + + R + + L V + AC+ YE
Sbjct: 439 FLLAGFVSLFRIRTIMKH--DGTKTEKLEKLMVRIGVFSVLYTVPATIVLACYFYEQAFR 496
Query: 187 DLWKDSFKRNIICRLEAGQERQKECLTGSRPSIS----VLQLRLLCCFAAGALMSSWTWT 354
+ W+ ++ L+ + C G P +S V ++ L G W W+
Sbjct: 497 EHWERTW------LLQTCKSYAVPCPPGHFPPMSPDFTVFMIKYLMTMIVGITTGFWIWS 550
>AB017365-1|BAA34668.1| 574|Homo sapiens frizzled-7 protein.
Length = 574
Score = 32.3 bits (70), Expect = 2.1
Identities = 27/120 (22%), Positives = 46/120 (38%), Gaps = 4/120 (3%)
Frame = +1
Query: 7 FLLRGVFSLVVVRVSSKDVISPRASNKIRRTITRCSITAALVAVFICVTFACHIYEFRNA 186
FLL G SL +R K + K+ + + R + + L V + AC+ YE
Sbjct: 439 FLLAGFVSLFRIRTIMKH--DGTKTEKLEKLMVRIGVFSVLYTVPATIVLACYFYEQAFR 496
Query: 187 DLWKDSFKRNIICRLEAGQERQKECLTGSRPSIS----VLQLRLLCCFAAGALMSSWTWT 354
+ W+ ++ L+ + C G P +S V ++ L G W W+
Sbjct: 497 EHWERTW------LLQTCKSYAVPCPPGHFPPMSPDFTVFMIKYLMTMIVGITTGFWIWS 550
>AF167585-1|AAF15419.1| 78|Homo sapiens immunoglobulin heavy chain
variable region protein.
Length = 78
Score = 31.1 bits (67), Expect = 4.8
Identities = 14/40 (35%), Positives = 24/40 (60%)
Frame = +1
Query: 76 ASNKIRRTITRCSITAALVAVFICVTFACHIYEFRNADLW 195
A++K + ++ S+TAA AV+ C A Y++R+ D W
Sbjct: 37 ATSKNQFSLKLSSVTAADTAVYYCARVAWSGYDYRDFDYW 76
>AB010881-1|BAA32424.1| 574|Homo sapiens FzE3 protein.
Length = 574
Score = 30.7 bits (66), Expect = 6.4
Identities = 26/120 (21%), Positives = 45/120 (37%), Gaps = 4/120 (3%)
Frame = +1
Query: 7 FLLRGVFSLVVVRVSSKDVISPRASNKIRRTITRCSITAALVAVFICVTFACHIYEFRNA 186
FLL G S +R K + K+ + + R + + L V + AC+ YE
Sbjct: 439 FLLAGFVSFFRIRTIMKH--DGTKTEKLEKLMVRIGVFSVLYTVPATIVLACYFYEQAFR 496
Query: 187 DLWKDSFKRNIICRLEAGQERQKECLTGSRPSIS----VLQLRLLCCFAAGALMSSWTWT 354
+ W+ ++ L+ + C G P +S V ++ L G W W+
Sbjct: 497 EHWERTW------LLQTCKSYAVPCPPGHFPPMSPDFTVFMIKCLMTMIVGITTGFWIWS 550
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 100,109,744
Number of Sequences: 237096
Number of extensions: 1876632
Number of successful extensions: 4632
Number of sequences better than 10.0: 31
Number of HSP's better than 10.0 without gapping: 4241
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4613
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9869080686
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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