Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= brP-1080
(700 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BT007290-1|AAP35954.1| 346|Homo sapiens SUMO-1 activating enzym... 189 7e-48
BC018271-1|AAH18271.1| 346|Homo sapiens SUMO1 activating enzyme... 189 7e-48
BC003611-1|AAH03611.1| 346|Homo sapiens SUMO1 activating enzyme... 189 7e-48
BC000344-1|AAH00344.1| 346|Homo sapiens SUMO1 activating enzyme... 189 7e-48
AF110956-1|AAD24433.1| 346|Homo sapiens SUMO-1 activating enzym... 189 7e-48
AF090385-1|AAD12785.2| 346|Homo sapiens SUMO-1-activating enzym... 189 7e-48
AF046025-1|AAD23902.2| 346|Homo sapiens activation of Sentrin/S... 189 7e-48
M58028-1|AAA61246.1| 1058|Homo sapiens ubiquitin-activating enzy... 107 5e-23
BC013041-1|AAH13041.1| 1058|Homo sapiens ubiquitin-activating en... 107 5e-23
AL513366-12|CAI41708.1| 1058|Homo sapiens ubiquitin-activating e... 107 5e-23
AL513366-11|CAI41707.1| 271|Homo sapiens ubiquitin-activating e... 107 5e-23
AL513366-10|CAI41706.1| 284|Homo sapiens ubiquitin-activating e... 107 5e-23
X56976-1|CAA40296.1| 1058|Homo sapiens ubiquitin activating enzy... 104 4e-22
L13852-1|AAA75388.1| 1011|Homo sapiens ubiquitin-activating enzy... 94 4e-19
BT007026-1|AAP35672.1| 1012|Homo sapiens ubiquitin-activating en... 94 4e-19
BC006378-1|AAH06378.1| 1012|Homo sapiens ubiquitin-activating en... 94 4e-19
AL513366-8|CAI41704.1| 234|Homo sapiens ubiquitin-activating en... 94 4e-19
AF294032-1|AAG49557.1| 1011|Homo sapiens UBE1L protein protein. 94 4e-19
AL832015-1|CAD89908.1| 1052|Homo sapiens hypothetical protein pr... 93 7e-19
EF623993-1|ABR25253.1| 1052|Homo sapiens ubiquitin-activating en... 93 9e-19
BC126486-1|AAI26487.1| 1052|Homo sapiens ubiquitin-activating en... 93 9e-19
BC126484-1|AAI26485.1| 1052|Homo sapiens ubiquitin-activating en... 93 9e-19
BC031637-1|AAH31637.1| 389|Homo sapiens UBE1L2 protein protein. 93 9e-19
AL832458-1|CAD89959.1| 1052|Homo sapiens hypothetical protein pr... 93 9e-19
AB014773-1|BAB19785.1| 1052|Homo sapiens MOP-4 protein. 93 9e-19
AK094969-1|BAC04463.1| 340|Homo sapiens protein ( Homo sapiens ... 93 1e-18
U50939-1|AAC50477.1| 534|Homo sapiens amyloid precursor protein... 87 4e-17
BC013301-1|AAH13301.1| 534|Homo sapiens amyloid beta precursor ... 87 4e-17
BC000480-1|AAH00480.1| 534|Homo sapiens amyloid beta precursor ... 87 4e-17
AY197612-1|AAP35030.1| 534|Homo sapiens protooncogene protein 1... 87 4e-17
AC004638-1|AAC23784.1| 534|Homo sapiens amyloid precursor prote... 87 4e-17
AL513366-9|CAI41705.1| 173|Homo sapiens ubiquitin-activating en... 86 1e-16
AL513366-7|CAI41703.1| 195|Homo sapiens ubiquitin-activating en... 81 4e-15
BC022853-1|AAH22853.1| 463|Homo sapiens ubiquitin-activating en... 63 1e-09
AF046024-1|AAC27648.1| 442|Homo sapiens UBA3 protein. 63 1e-09
AB012190-1|BAA33144.1| 442|Homo sapiens Nedd8-activating enzyme... 63 1e-09
CR533537-1|CAG38568.1| 463|Homo sapiens UBE1C protein. 62 2e-09
X52897-1|CAA37078.1| 803|Homo sapiens protein ( Human A1S9 mRNA... 53 9e-07
U35832-1|AAC99992.1| 640|Homo sapiens anthracycline-associated ... 52 1e-06
CR456756-1|CAG33037.1| 640|Homo sapiens UBA2 protein. 52 1e-06
BT009781-1|AAP88783.1| 640|Homo sapiens SUMO-1 activating enzym... 52 1e-06
BC003153-1|AAH03153.1| 640|Homo sapiens SUMO1 activating enzyme... 52 1e-06
AF110957-1|AAD24434.1| 640|Homo sapiens SUMO-1 activating enzym... 52 1e-06
AF090384-1|AAD12784.1| 640|Homo sapiens SUMO-1-activating enzym... 52 1e-06
AF079566-1|AAD23914.1| 640|Homo sapiens ubiquitin-like protein ... 52 1e-06
BC015939-1|AAH15939.1| 460|Homo sapiens molybdenum cofactor syn... 49 2e-05
AL034553-7|CAB53750.1| 460|Homo sapiens molybdenum cofactor syn... 49 2e-05
AF102544-1|AAC72412.1| 460|Homo sapiens molybdopterin synthase ... 49 2e-05
AC096720-2|AAY40999.1| 787|Homo sapiens unknown protein. 42 0.002
BC009737-1|AAH09737.1| 404|Homo sapiens ubiquitin-activating en... 40 0.009
AY253672-1|AAP79600.1| 404|Homo sapiens ThiFP1 protein. 40 0.009
AL136757-1|CAB66691.1| 404|Homo sapiens hypothetical protein pr... 40 0.009
AK027563-1|BAB55199.1| 348|Homo sapiens protein ( Homo sapiens ... 40 0.009
AK026904-1|BAB15587.1| 404|Homo sapiens protein ( Homo sapiens ... 40 0.009
AB154406-1|BAD15375.1| 404|Homo sapiens Ubiquitin activating en... 40 0.009
>BT007290-1|AAP35954.1| 346|Homo sapiens SUMO-1 activating enzyme
subunit 1 protein.
Length = 346
Score = 189 bits (461), Expect = 7e-48
Identities = 87/164 (53%), Positives = 122/164 (74%)
Frame = +3
Query: 114 LSEAEAEQYDRQIRLWGLDSQKRLRAAKVLIIGLSGLGAEIAKNVILTGVKSVCLLDNEK 293
+SE EA QYDRQIRLWGL++QKRLRA++VL++GL GLGAEIAKN+IL GVK + +LD+E+
Sbjct: 11 ISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQ 70
Query: 294 LKQIDLYSQFLCPPDKIGVNRAEGSLERARGLNPMVDVTSHTKGVDELPDSFFTEFDVVC 473
+ D +QFL +G NRAE SLERA+ LNPMVDV T+ +++ P+SFFT+FD VC
Sbjct: 71 VTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDAVC 130
Query: 474 ATGLKQEQFERINNACRDSNKKFICGDVWGTYGYMFSDLVDHEY 605
T ++ +++ C ++ KF GDV+G +GY F++L +HE+
Sbjct: 131 LTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEF 174
>BC018271-1|AAH18271.1| 346|Homo sapiens SUMO1 activating enzyme
subunit 1 protein.
Length = 346
Score = 189 bits (461), Expect = 7e-48
Identities = 87/164 (53%), Positives = 122/164 (74%)
Frame = +3
Query: 114 LSEAEAEQYDRQIRLWGLDSQKRLRAAKVLIIGLSGLGAEIAKNVILTGVKSVCLLDNEK 293
+SE EA QYDRQIRLWGL++QKRLRA++VL++GL GLGAEIAKN+IL GVK + +LD+E+
Sbjct: 11 ISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQ 70
Query: 294 LKQIDLYSQFLCPPDKIGVNRAEGSLERARGLNPMVDVTSHTKGVDELPDSFFTEFDVVC 473
+ D +QFL +G NRAE SLERA+ LNPMVDV T+ +++ P+SFFT+FD VC
Sbjct: 71 VTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDAVC 130
Query: 474 ATGLKQEQFERINNACRDSNKKFICGDVWGTYGYMFSDLVDHEY 605
T ++ +++ C ++ KF GDV+G +GY F++L +HE+
Sbjct: 131 LTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEF 174
>BC003611-1|AAH03611.1| 346|Homo sapiens SUMO1 activating enzyme
subunit 1 protein.
Length = 346
Score = 189 bits (461), Expect = 7e-48
Identities = 87/164 (53%), Positives = 122/164 (74%)
Frame = +3
Query: 114 LSEAEAEQYDRQIRLWGLDSQKRLRAAKVLIIGLSGLGAEIAKNVILTGVKSVCLLDNEK 293
+SE EA QYDRQIRLWGL++QKRLRA++VL++GL GLGAEIAKN+IL GVK + +LD+E+
Sbjct: 11 ISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQ 70
Query: 294 LKQIDLYSQFLCPPDKIGVNRAEGSLERARGLNPMVDVTSHTKGVDELPDSFFTEFDVVC 473
+ D +QFL +G NRAE SLERA+ LNPMVDV T+ +++ P+SFFT+FD VC
Sbjct: 71 VTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDAVC 130
Query: 474 ATGLKQEQFERINNACRDSNKKFICGDVWGTYGYMFSDLVDHEY 605
T ++ +++ C ++ KF GDV+G +GY F++L +HE+
Sbjct: 131 LTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEF 174
>BC000344-1|AAH00344.1| 346|Homo sapiens SUMO1 activating enzyme
subunit 1 protein.
Length = 346
Score = 189 bits (461), Expect = 7e-48
Identities = 87/164 (53%), Positives = 122/164 (74%)
Frame = +3
Query: 114 LSEAEAEQYDRQIRLWGLDSQKRLRAAKVLIIGLSGLGAEIAKNVILTGVKSVCLLDNEK 293
+SE EA QYDRQIRLWGL++QKRLRA++VL++GL GLGAEIAKN+IL GVK + +LD+E+
Sbjct: 11 ISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQ 70
Query: 294 LKQIDLYSQFLCPPDKIGVNRAEGSLERARGLNPMVDVTSHTKGVDELPDSFFTEFDVVC 473
+ D +QFL +G NRAE SLERA+ LNPMVDV T+ +++ P+SFFT+FD VC
Sbjct: 71 VTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDAVC 130
Query: 474 ATGLKQEQFERINNACRDSNKKFICGDVWGTYGYMFSDLVDHEY 605
T ++ +++ C ++ KF GDV+G +GY F++L +HE+
Sbjct: 131 LTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEF 174
>AF110956-1|AAD24433.1| 346|Homo sapiens SUMO-1 activating enzyme
subunit 1 protein.
Length = 346
Score = 189 bits (461), Expect = 7e-48
Identities = 87/164 (53%), Positives = 122/164 (74%)
Frame = +3
Query: 114 LSEAEAEQYDRQIRLWGLDSQKRLRAAKVLIIGLSGLGAEIAKNVILTGVKSVCLLDNEK 293
+SE EA QYDRQIRLWGL++QKRLRA++VL++GL GLGAEIAKN+IL GVK + +LD+E+
Sbjct: 11 ISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQ 70
Query: 294 LKQIDLYSQFLCPPDKIGVNRAEGSLERARGLNPMVDVTSHTKGVDELPDSFFTEFDVVC 473
+ D +QFL +G NRAE SLERA+ LNPMVDV T+ +++ P+SFFT+FD VC
Sbjct: 71 VTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDAVC 130
Query: 474 ATGLKQEQFERINNACRDSNKKFICGDVWGTYGYMFSDLVDHEY 605
T ++ +++ C ++ KF GDV+G +GY F++L +HE+
Sbjct: 131 LTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEF 174
>AF090385-1|AAD12785.2| 346|Homo sapiens SUMO-1-activating enzyme
E1 N subunit protein.
Length = 346
Score = 189 bits (461), Expect = 7e-48
Identities = 87/164 (53%), Positives = 122/164 (74%)
Frame = +3
Query: 114 LSEAEAEQYDRQIRLWGLDSQKRLRAAKVLIIGLSGLGAEIAKNVILTGVKSVCLLDNEK 293
+SE EA QYDRQIRLWGL++QKRLRA++VL++GL GLGAEIAKN+IL GVK + +LD+E+
Sbjct: 11 ISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQ 70
Query: 294 LKQIDLYSQFLCPPDKIGVNRAEGSLERARGLNPMVDVTSHTKGVDELPDSFFTEFDVVC 473
+ D +QFL +G NRAE SLERA+ LNPMVDV T+ +++ P+SFFT+FD VC
Sbjct: 71 VTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDAVC 130
Query: 474 ATGLKQEQFERINNACRDSNKKFICGDVWGTYGYMFSDLVDHEY 605
T ++ +++ C ++ KF GDV+G +GY F++L +HE+
Sbjct: 131 LTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEF 174
>AF046025-1|AAD23902.2| 346|Homo sapiens activation of Sentrin/SUMO
protein AOS1 protein.
Length = 346
Score = 189 bits (461), Expect = 7e-48
Identities = 87/164 (53%), Positives = 122/164 (74%)
Frame = +3
Query: 114 LSEAEAEQYDRQIRLWGLDSQKRLRAAKVLIIGLSGLGAEIAKNVILTGVKSVCLLDNEK 293
+SE EA QYDRQIRLWGL++QKRLRA++VL++GL GLGAEIAKN+IL GVK + +LD+E+
Sbjct: 11 ISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQ 70
Query: 294 LKQIDLYSQFLCPPDKIGVNRAEGSLERARGLNPMVDVTSHTKGVDELPDSFFTEFDVVC 473
+ D +QFL +G NRAE SLERA+ LNPMVDV T+ +++ P+SFFT+FD VC
Sbjct: 71 VTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDAVC 130
Query: 474 ATGLKQEQFERINNACRDSNKKFICGDVWGTYGYMFSDLVDHEY 605
T ++ +++ C ++ KF GDV+G +GY F++L +HE+
Sbjct: 131 LTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEF 174
>M58028-1|AAA61246.1| 1058|Homo sapiens ubiquitin-activating enzyme
E1 protein.
Length = 1058
Score = 107 bits (256), Expect = 5e-23
Identities = 64/159 (40%), Positives = 87/159 (54%), Gaps = 2/159 (1%)
Frame = +3
Query: 117 SEAEAEQ--YDRQIRLWGLDSQKRLRAAKVLIIGLSGLGAEIAKNVILTGVKSVCLLDNE 290
SEA+ ++ Y RQ+ + G ++ KRL+ + VL+ GL GLG EIAKN+IL GVK+V L D
Sbjct: 46 SEADIDEGLYSRQLYVLGHEAMKRLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQG 105
Query: 291 KLKQIDLYSQFLCPPDKIGVNRAEGSLERARGLNPMVDVTSHTKGVDELPDSFFTEFDVV 470
+ DL SQF + IG NRAE S R LN V VT++T L + F + F VV
Sbjct: 106 TAQWADLSSQFYLREEDIGKNRAEVSQPRLAELNSYVPVTAYT---GPLVEDFLSGFQVV 162
Query: 471 CATGLKQEQFERINNACRDSNKKFICGDVWGTYGYMFSD 587
T E R+ C + K + D G +G +F D
Sbjct: 163 VLTNTPLEDQLRVGEFCHNRGIKLVVADTRGLFGQLFCD 201
Score = 53.2 bits (122), Expect = 9e-07
Identities = 33/122 (27%), Positives = 59/122 (48%), Gaps = 10/122 (8%)
Frame = +3
Query: 135 QYDRQIRLWGLDSQKRLRAAKVLIIGLSGLGAEIAKNVILTGVK-----SVCLLDNEKLK 299
+YD Q+ ++G D Q++L K ++G +G E+ KN + G+ + + D + ++
Sbjct: 450 RYDGQVAVFGSDLQEKLGKQKYFLVGAGAIGCELLKNFAMIGLGCGEGGEIIVTDMDTIE 509
Query: 300 QIDLYSQFLCPPDKIGVNRAEGSLERARGLNPMVDVTSHTKGVDE-----LPDSFFTEFD 464
+ +L QFL P + +++ + R +NP + VTSH V D FF D
Sbjct: 510 KSNLNRQFLFRPWDVTKLKSDTAAAAVRQMNPHIRVTSHQNRVGPDTERIYDDDFFQNLD 569
Query: 465 VV 470
V
Sbjct: 570 GV 571
>BC013041-1|AAH13041.1| 1058|Homo sapiens ubiquitin-activating
enzyme E1 (A1S9T and BN75 temperature sensitivity
compleme protein.
Length = 1058
Score = 107 bits (256), Expect = 5e-23
Identities = 64/159 (40%), Positives = 87/159 (54%), Gaps = 2/159 (1%)
Frame = +3
Query: 117 SEAEAEQ--YDRQIRLWGLDSQKRLRAAKVLIIGLSGLGAEIAKNVILTGVKSVCLLDNE 290
SEA+ ++ Y RQ+ + G ++ KRL+ + VL+ GL GLG EIAKN+IL GVK+V L D
Sbjct: 46 SEADIDEGLYSRQLYVLGHEAMKRLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQG 105
Query: 291 KLKQIDLYSQFLCPPDKIGVNRAEGSLERARGLNPMVDVTSHTKGVDELPDSFFTEFDVV 470
+ DL SQF + IG NRAE S R LN V VT++T L + F + F VV
Sbjct: 106 TAQWADLSSQFYLREEDIGKNRAEVSQPRLAELNSYVPVTAYT---GPLVEDFLSGFQVV 162
Query: 471 CATGLKQEQFERINNACRDSNKKFICGDVWGTYGYMFSD 587
T E R+ C + K + D G +G +F D
Sbjct: 163 VLTNTPLEDQLRVGEFCHNRGIKLVVADTRGLFGQLFCD 201
Score = 53.2 bits (122), Expect = 9e-07
Identities = 33/122 (27%), Positives = 59/122 (48%), Gaps = 10/122 (8%)
Frame = +3
Query: 135 QYDRQIRLWGLDSQKRLRAAKVLIIGLSGLGAEIAKNVILTGVK-----SVCLLDNEKLK 299
+YD Q+ ++G D Q++L K ++G +G E+ KN + G+ + + D + ++
Sbjct: 450 RYDGQVAVFGSDLQEKLGKQKYFLVGAGAIGCELLKNFAMIGLGCGEGGEIIVTDMDTIE 509
Query: 300 QIDLYSQFLCPPDKIGVNRAEGSLERARGLNPMVDVTSHTKGVDE-----LPDSFFTEFD 464
+ +L QFL P + +++ + R +NP + VTSH V D FF D
Sbjct: 510 KSNLNRQFLFRPWDVTKLKSDTAAAAVRQMNPHIRVTSHQNRVGPDTERIYDDDFFQNLD 569
Query: 465 VV 470
V
Sbjct: 570 GV 571
>AL513366-12|CAI41708.1| 1058|Homo sapiens ubiquitin-activating
enzyme E1 (A1S9T and BN75 temperature sensitivity
compleme protein.
Length = 1058
Score = 107 bits (256), Expect = 5e-23
Identities = 64/159 (40%), Positives = 87/159 (54%), Gaps = 2/159 (1%)
Frame = +3
Query: 117 SEAEAEQ--YDRQIRLWGLDSQKRLRAAKVLIIGLSGLGAEIAKNVILTGVKSVCLLDNE 290
SEA+ ++ Y RQ+ + G ++ KRL+ + VL+ GL GLG EIAKN+IL GVK+V L D
Sbjct: 46 SEADIDEGLYSRQLYVLGHEAMKRLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQG 105
Query: 291 KLKQIDLYSQFLCPPDKIGVNRAEGSLERARGLNPMVDVTSHTKGVDELPDSFFTEFDVV 470
+ DL SQF + IG NRAE S R LN V VT++T L + F + F VV
Sbjct: 106 TAQWADLSSQFYLREEDIGKNRAEVSQPRLAELNSYVPVTAYT---GPLVEDFLSGFQVV 162
Query: 471 CATGLKQEQFERINNACRDSNKKFICGDVWGTYGYMFSD 587
T E R+ C + K + D G +G +F D
Sbjct: 163 VLTNTPLEDQLRVGEFCHNRGIKLVVADTRGLFGQLFCD 201
Score = 53.2 bits (122), Expect = 9e-07
Identities = 33/122 (27%), Positives = 59/122 (48%), Gaps = 10/122 (8%)
Frame = +3
Query: 135 QYDRQIRLWGLDSQKRLRAAKVLIIGLSGLGAEIAKNVILTGVK-----SVCLLDNEKLK 299
+YD Q+ ++G D Q++L K ++G +G E+ KN + G+ + + D + ++
Sbjct: 450 RYDGQVAVFGSDLQEKLGKQKYFLVGAGAIGCELLKNFAMIGLGCGEGGEIIVTDMDTIE 509
Query: 300 QIDLYSQFLCPPDKIGVNRAEGSLERARGLNPMVDVTSHTKGVDE-----LPDSFFTEFD 464
+ +L QFL P + +++ + R +NP + VTSH V D FF D
Sbjct: 510 KSNLNRQFLFRPWDVTKLKSDTAAAAVRQMNPHIRVTSHQNRVGPDTERIYDDDFFQNLD 569
Query: 465 VV 470
V
Sbjct: 570 GV 571
>AL513366-11|CAI41707.1| 271|Homo sapiens ubiquitin-activating
enzyme E1 (A1S9T and BN75 temperature sensitivity
compleme protein.
Length = 271
Score = 107 bits (256), Expect = 5e-23
Identities = 64/159 (40%), Positives = 87/159 (54%), Gaps = 2/159 (1%)
Frame = +3
Query: 117 SEAEAEQ--YDRQIRLWGLDSQKRLRAAKVLIIGLSGLGAEIAKNVILTGVKSVCLLDNE 290
SEA+ ++ Y RQ+ + G ++ KRL+ + VL+ GL GLG EIAKN+IL GVK+V L D
Sbjct: 46 SEADIDEGLYSRQLYVLGHEAMKRLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQG 105
Query: 291 KLKQIDLYSQFLCPPDKIGVNRAEGSLERARGLNPMVDVTSHTKGVDELPDSFFTEFDVV 470
+ DL SQF + IG NRAE S R LN V VT++T L + F + F VV
Sbjct: 106 TAQWADLSSQFYLREEDIGKNRAEVSQPRLAELNSYVPVTAYT---GPLVEDFLSGFQVV 162
Query: 471 CATGLKQEQFERINNACRDSNKKFICGDVWGTYGYMFSD 587
T E R+ C + K + D G +G +F D
Sbjct: 163 VLTNTPLEDQLRVGEFCHNRGIKLVVADTRGLFGQLFCD 201
>AL513366-10|CAI41706.1| 284|Homo sapiens ubiquitin-activating
enzyme E1 (A1S9T and BN75 temperature sensitivity
compleme protein.
Length = 284
Score = 107 bits (256), Expect = 5e-23
Identities = 64/159 (40%), Positives = 87/159 (54%), Gaps = 2/159 (1%)
Frame = +3
Query: 117 SEAEAEQ--YDRQIRLWGLDSQKRLRAAKVLIIGLSGLGAEIAKNVILTGVKSVCLLDNE 290
SEA+ ++ Y RQ+ + G ++ KRL+ + VL+ GL GLG EIAKN+IL GVK+V L D
Sbjct: 60 SEADIDEGLYSRQLYVLGHEAMKRLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQG 119
Query: 291 KLKQIDLYSQFLCPPDKIGVNRAEGSLERARGLNPMVDVTSHTKGVDELPDSFFTEFDVV 470
+ DL SQF + IG NRAE S R LN V VT++T L + F + F VV
Sbjct: 120 TAQWADLSSQFYLREEDIGKNRAEVSQPRLAELNSYVPVTAYT---GPLVEDFLSGFQVV 176
Query: 471 CATGLKQEQFERINNACRDSNKKFICGDVWGTYGYMFSD 587
T E R+ C + K + D G +G +F D
Sbjct: 177 VLTNTPLEDQLRVGEFCHNRGIKLVVADTRGLFGQLFCD 215
>X56976-1|CAA40296.1| 1058|Homo sapiens ubiquitin activating enzyme
E1 protein.
Length = 1058
Score = 104 bits (249), Expect = 4e-22
Identities = 63/159 (39%), Positives = 86/159 (54%), Gaps = 2/159 (1%)
Frame = +3
Query: 117 SEAEAEQ--YDRQIRLWGLDSQKRLRAAKVLIIGLSGLGAEIAKNVILTGVKSVCLLDNE 290
SEA+ ++ Y RQ+ + G ++ KRL+ + VL+ GL GLG EIAKN+IL GVK+V L D
Sbjct: 46 SEADIDEGLYSRQLYVLGHEAMKRLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQG 105
Query: 291 KLKQIDLYSQFLCPPDKIGVNRAEGSLERARGLNPMVDVTSHTKGVDELPDSFFTEFDVV 470
+ DL SQF + IG NRAE S R LN V VT++T L + F + F VV
Sbjct: 106 TAQWADLSSQFYLREEDIGKNRAEVSQPRLAELNSYVPVTAYT---GPLVEDFLSGFQVV 162
Query: 471 CATGLKQEQFERINNACRDSNKKFICGDVWGTYGYMFSD 587
T E R+ C + K + G +G +F D
Sbjct: 163 VLTNTPLEDQLRVGEFCHNRGIKLVVAGTRGLFGQLFCD 201
Score = 53.2 bits (122), Expect = 9e-07
Identities = 33/122 (27%), Positives = 59/122 (48%), Gaps = 10/122 (8%)
Frame = +3
Query: 135 QYDRQIRLWGLDSQKRLRAAKVLIIGLSGLGAEIAKNVILTGVK-----SVCLLDNEKLK 299
+YD Q+ ++G D Q++L K ++G +G E+ KN + G+ + + D + ++
Sbjct: 450 RYDGQVAVFGSDLQEKLGKQKYFLVGAGAIGCELLKNFAMIGLGCGEGGEIIVTDMDTIE 509
Query: 300 QIDLYSQFLCPPDKIGVNRAEGSLERARGLNPMVDVTSHTKGVDE-----LPDSFFTEFD 464
+ +L QFL P + +++ + R +NP + VTSH V D FF D
Sbjct: 510 KSNLNRQFLFRPWDVTKLKSDTAAAAVRQMNPHIRVTSHQNRVGPDTERIYDDDFFQNLD 569
Query: 465 VV 470
V
Sbjct: 570 GV 571
>L13852-1|AAA75388.1| 1011|Homo sapiens ubiquitin-activating enzyme
E1-related protein protein.
Length = 1011
Score = 94.3 bits (224), Expect = 4e-19
Identities = 54/154 (35%), Positives = 79/154 (51%)
Frame = +3
Query: 126 EAEQYDRQIRLWGLDSQKRLRAAKVLIIGLSGLGAEIAKNVILTGVKSVCLLDNEKLKQI 305
+ E Y RQ+ + G + +R++ A+VL+ GL GLGAE+AKN++L GV S+ L D
Sbjct: 11 DEELYSRQLYVLGSPAMQRIQGARVLVSGLQGLGAEVAKNLVLMGVGSLTLHDPHPTCWS 70
Query: 306 DLYSQFLCPPDKIGVNRAEGSLERARGLNPMVDVTSHTKGVDELPDSFFTEFDVVCATGL 485
DL +QFL + +RAE S E LN V V HT ++ + +F VV T
Sbjct: 71 DLAAQFLLSEQDLERSRAEASQELLAQLNRAVQVVVHT---GDITEDLLLDFQVVVLTAA 127
Query: 486 KQEQFERINNACRDSNKKFICGDVWGTYGYMFSD 587
K E+ ++ C F+ D G G +F D
Sbjct: 128 KLEEQLKVGTLCHKHGVCFLAADTRGLVGQLFCD 161
Score = 58.0 bits (134), Expect = 3e-08
Identities = 46/157 (29%), Positives = 75/157 (47%), Gaps = 11/157 (7%)
Frame = +3
Query: 135 QYDRQIRLWGLDSQKRLRAAKVLIIGLSGLGAEIAKNVILTGVKS-----VCLLDNEKLK 299
+YD QI ++G Q++LR L++G +G E+ K L G+ + + ++D + ++
Sbjct: 413 RYDGQIAVFGAGFQEKLRRQHYLLVGAGAIGCELLKVFALVGLGAGNSGGLTVVDMDHIE 472
Query: 300 QIDLYSQFLCPPDKIGVNRAEGSLERARGLNPMVDVTSHTKGVDELP-----DSFFTEFD 464
+ +L QFL +G +AE + ARGLNP + V T +D D+FF+ D
Sbjct: 473 RSNLSRQFLFRSQDVGRPKAEVAAAAARGLNPDLQVIPLTYPLDPTTEHIYGDNFFSRVD 532
Query: 465 VVCATGLKQEQFER-INNACRDSNKKFICGDVWGTYG 572
V A L Q R + C K + GT+G
Sbjct: 533 GV-AAALDSFQARRYVAARCTHYLKPLLEAGTSGTWG 568
>BT007026-1|AAP35672.1| 1012|Homo sapiens ubiquitin-activating
enzyme E1-like protein.
Length = 1012
Score = 94.3 bits (224), Expect = 4e-19
Identities = 54/154 (35%), Positives = 79/154 (51%)
Frame = +3
Query: 126 EAEQYDRQIRLWGLDSQKRLRAAKVLIIGLSGLGAEIAKNVILTGVKSVCLLDNEKLKQI 305
+ E Y RQ+ + G + +R++ A+VL+ GL GLGAE+AKN++L GV S+ L D
Sbjct: 11 DEELYSRQLYVLGSPAMQRIQGARVLVSGLQGLGAEVAKNLVLMGVGSLTLHDPHPTCWS 70
Query: 306 DLYSQFLCPPDKIGVNRAEGSLERARGLNPMVDVTSHTKGVDELPDSFFTEFDVVCATGL 485
DL +QFL + +RAE S E LN V V HT ++ + +F VV T
Sbjct: 71 DLAAQFLLSEQDLERSRAEASQELLAQLNRAVQVVVHT---GDITEDLLLDFQVVVLTAA 127
Query: 486 KQEQFERINNACRDSNKKFICGDVWGTYGYMFSD 587
K E+ ++ C F+ D G G +F D
Sbjct: 128 KLEEQLKVGTLCHKHGVCFLAADTRGLVGQLFCD 161
Score = 58.0 bits (134), Expect = 3e-08
Identities = 46/157 (29%), Positives = 75/157 (47%), Gaps = 11/157 (7%)
Frame = +3
Query: 135 QYDRQIRLWGLDSQKRLRAAKVLIIGLSGLGAEIAKNVILTGVKS-----VCLLDNEKLK 299
+YD QI ++G Q++LR L++G +G E+ K L G+ + + ++D + ++
Sbjct: 414 RYDGQIAVFGAGFQEKLRRQHYLLVGAGAIGCELLKVFALVGLGAGNSGGLTVVDMDHIE 473
Query: 300 QIDLYSQFLCPPDKIGVNRAEGSLERARGLNPMVDVTSHTKGVDELP-----DSFFTEFD 464
+ +L QFL +G +AE + ARGLNP + V T +D D+FF+ D
Sbjct: 474 RSNLSRQFLFRSQDVGRPKAEVAAAAARGLNPDLQVIPLTYPLDPTTEHIYGDNFFSRVD 533
Query: 465 VVCATGLKQEQFER-INNACRDSNKKFICGDVWGTYG 572
V A L Q R + C K + GT+G
Sbjct: 534 GV-AAALDSFQARRYVAARCTHYLKPLLEAGTSGTWG 569
>BC006378-1|AAH06378.1| 1012|Homo sapiens ubiquitin-activating
enzyme E1-like protein.
Length = 1012
Score = 94.3 bits (224), Expect = 4e-19
Identities = 54/154 (35%), Positives = 79/154 (51%)
Frame = +3
Query: 126 EAEQYDRQIRLWGLDSQKRLRAAKVLIIGLSGLGAEIAKNVILTGVKSVCLLDNEKLKQI 305
+ E Y RQ+ + G + +R++ A+VL+ GL GLGAE+AKN++L GV S+ L D
Sbjct: 11 DEELYSRQLYVLGSPAMQRIQGARVLVSGLQGLGAEVAKNLVLMGVGSLTLHDPHPTCWS 70
Query: 306 DLYSQFLCPPDKIGVNRAEGSLERARGLNPMVDVTSHTKGVDELPDSFFTEFDVVCATGL 485
DL +QFL + +RAE S E LN V V HT ++ + +F VV T
Sbjct: 71 DLAAQFLLSEQDLERSRAEASQELLAQLNRAVQVVVHT---GDITEDLLLDFQVVVLTAA 127
Query: 486 KQEQFERINNACRDSNKKFICGDVWGTYGYMFSD 587
K E+ ++ C F+ D G G +F D
Sbjct: 128 KLEEQLKVGTLCHKHGVCFLAADTRGLVGQLFCD 161
Score = 58.0 bits (134), Expect = 3e-08
Identities = 46/157 (29%), Positives = 75/157 (47%), Gaps = 11/157 (7%)
Frame = +3
Query: 135 QYDRQIRLWGLDSQKRLRAAKVLIIGLSGLGAEIAKNVILTGVKS-----VCLLDNEKLK 299
+YD QI ++G Q++LR L++G +G E+ K L G+ + + ++D + ++
Sbjct: 414 RYDGQIAVFGAGFQEKLRRQHYLLVGAGAIGCELLKVFALVGLGAGNSGGLTVVDMDHIE 473
Query: 300 QIDLYSQFLCPPDKIGVNRAEGSLERARGLNPMVDVTSHTKGVDELP-----DSFFTEFD 464
+ +L QFL +G +AE + ARGLNP + V T +D D+FF+ D
Sbjct: 474 RSNLSRQFLFRSQDVGRPKAEVAAAAARGLNPDLQVIPLTYPLDPTTEHIYGDNFFSRVD 533
Query: 465 VVCATGLKQEQFER-INNACRDSNKKFICGDVWGTYG 572
V A L Q R + C K + GT+G
Sbjct: 534 GV-AAALDSFQARRYVAARCTHYLKPLLEAGTSGTWG 569
>AL513366-8|CAI41704.1| 234|Homo sapiens ubiquitin-activating
enzyme E1 (A1S9T and BN75 temperature sensitivity
compleme protein.
Length = 234
Score = 94.3 bits (224), Expect = 4e-19
Identities = 58/139 (41%), Positives = 78/139 (56%), Gaps = 2/139 (1%)
Frame = +3
Query: 117 SEAEAEQ--YDRQIRLWGLDSQKRLRAAKVLIIGLSGLGAEIAKNVILTGVKSVCLLDNE 290
SEA+ ++ Y RQ+ + G ++ KRL+ + VL+ GL GLG EIAKN+IL GVK+V L D
Sbjct: 97 SEADIDEGLYSRQLYVLGHEAMKRLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQG 156
Query: 291 KLKQIDLYSQFLCPPDKIGVNRAEGSLERARGLNPMVDVTSHTKGVDELPDSFFTEFDVV 470
+ DL SQF + IG NRAE S R LN V VT++T L + F + F VV
Sbjct: 157 TAQWADLSSQFYLREEDIGKNRAEVSQPRLAELNSYVPVTAYT---GPLVEDFLSGFQVV 213
Query: 471 CATGLKQEQFERINNACRD 527
T E R+ C +
Sbjct: 214 VLTNTPLEDQLRVGEFCHN 232
>AF294032-1|AAG49557.1| 1011|Homo sapiens UBE1L protein protein.
Length = 1011
Score = 94.3 bits (224), Expect = 4e-19
Identities = 54/154 (35%), Positives = 79/154 (51%)
Frame = +3
Query: 126 EAEQYDRQIRLWGLDSQKRLRAAKVLIIGLSGLGAEIAKNVILTGVKSVCLLDNEKLKQI 305
+ E Y RQ+ + G + +R++ A+VL+ GL GLGAE+AKN++L GV S+ L D
Sbjct: 11 DEELYSRQLYVLGSPAMQRIQGARVLVSGLQGLGAEVAKNLVLMGVGSLTLHDPHPTCWS 70
Query: 306 DLYSQFLCPPDKIGVNRAEGSLERARGLNPMVDVTSHTKGVDELPDSFFTEFDVVCATGL 485
DL +QFL + +RAE S E LN V V HT ++ + +F VV T
Sbjct: 71 DLAAQFLLSEQDLERSRAEASQELLAQLNRAVQVVVHT---GDITEDLLLDFQVVVLTAA 127
Query: 486 KQEQFERINNACRDSNKKFICGDVWGTYGYMFSD 587
K E+ ++ C F+ D G G +F D
Sbjct: 128 KLEEQLKVGTLCHKHGVCFLAADTRGLVGQLFCD 161
Score = 58.0 bits (134), Expect = 3e-08
Identities = 46/157 (29%), Positives = 75/157 (47%), Gaps = 11/157 (7%)
Frame = +3
Query: 135 QYDRQIRLWGLDSQKRLRAAKVLIIGLSGLGAEIAKNVILTGVKS-----VCLLDNEKLK 299
+YD QI ++G Q++LR L++G +G E+ K L G+ + + ++D + ++
Sbjct: 413 RYDGQIAVFGAGFQEKLRRQHYLLVGAGAIGCELLKVFALVGLGAGNSGGLTVVDMDHIE 472
Query: 300 QIDLYSQFLCPPDKIGVNRAEGSLERARGLNPMVDVTSHTKGVDELP-----DSFFTEFD 464
+ +L QFL +G +AE + ARGLNP + V T +D D+FF+ D
Sbjct: 473 RSNLSRQFLFRSQDVGRPKAEVAAAAARGLNPDLQVIPLTYPLDPTTEHIYGDNFFSRVD 532
Query: 465 VVCATGLKQEQFER-INNACRDSNKKFICGDVWGTYG 572
V A L Q R + C K + GT+G
Sbjct: 533 GV-AAALDSFQARRYVAARCTHYLKPLLEAGTSGTWG 568
>AL832015-1|CAD89908.1| 1052|Homo sapiens hypothetical protein
protein.
Length = 1052
Score = 93.5 bits (222), Expect = 7e-19
Identities = 61/173 (35%), Positives = 90/173 (52%), Gaps = 5/173 (2%)
Frame = +3
Query: 120 EAEAEQYDRQIRLWGLDSQKRLRAAKVLIIGLSGLGAEIAKNVILTGVKSVCLLDNEKLK 299
E + Y RQ + G + +++ + V + G+ GLG EIAKN++L G+K+V + D EK +
Sbjct: 38 EIDDALYSRQRYVLGDTAMQKMAKSHVFLSGMGGLGLEIAKNLVLAGIKAVTIHDTEKCQ 97
Query: 300 QIDLYSQFLCPPDKI--GVNRAEGSLERARGLNPMVDVTSHTKGVDELPD-SFFTEFDVV 470
DL + F D + NRAE L+ LNP V VTS + +E D SF ++ V
Sbjct: 98 AWDLGTNFFLSEDDVVNKRNRAEAVLKHIAELNPYVHVTSSSAPFNETTDLSFLDKYQCV 157
Query: 471 CATGLKQEQFERINNACRDSNK--KFICGDVWGTYGYMFSDLVDHEYSXGDCT 623
T +K ++IN+ CR KFI DV G + +F D D E+ D T
Sbjct: 158 VLTEMKLPLQKKINDFCRSQCPPIKFISADVHGIWSRLFCDFGD-EFEVLDTT 209
Score = 41.9 bits (94), Expect = 0.002
Identities = 35/172 (20%), Positives = 72/172 (41%), Gaps = 11/172 (6%)
Frame = +3
Query: 93 VGNNEVELSEAEAEQYDRQIRLWGLDSQKRLRAAKVLIIGLSGLGAEIAKNVILTGVKS- 269
+G E E ++YD G ++L+ + ++G +G E+ KN L GV +
Sbjct: 428 LGKPECEEFLPRGDRYDALRACIGDTLCQKLQNLNIFLVGCGAIGCEMLKNFALLGVGTS 487
Query: 270 -----VCLLDNEKLKQIDLYSQFLCPPDKIGVNRAEGSLERARGLNPMVDVTSHTKGVDE 434
+ + D + +++ +L QFL P I ++ + + +N + + +H V
Sbjct: 488 KEKGMITVTDPDLIEKSNLNRQFLFRPHHIQKPKSYTAADATLKINSQIKIDAHLNKVCP 547
Query: 435 LP-----DSFFTEFDVVCATGLKQEQFERINNACRDSNKKFICGDVWGTYGY 575
D F+T+ DV+ E +++ C + + + GT G+
Sbjct: 548 TTETIYNDEFYTKQDVIITALDNVEARRYVDSRCLANLRPLLDSGTMGTKGH 599
>EF623993-1|ABR25253.1| 1052|Homo sapiens ubiquitin-activating
enzyme 6 protein.
Length = 1052
Score = 93.1 bits (221), Expect = 9e-19
Identities = 61/173 (35%), Positives = 90/173 (52%), Gaps = 5/173 (2%)
Frame = +3
Query: 120 EAEAEQYDRQIRLWGLDSQKRLRAAKVLIIGLSGLGAEIAKNVILTGVKSVCLLDNEKLK 299
E + Y RQ + G + +++ + V + G+ GLG EIAKN++L G+K+V + D EK +
Sbjct: 38 EIDDALYSRQRYVLGDTAMQKMAKSHVFLSGMGGLGLEIAKNLVLAGIKAVTIHDTEKCQ 97
Query: 300 QIDLYSQFLCPPDKI--GVNRAEGSLERARGLNPMVDVTSHTKGVDELPD-SFFTEFDVV 470
DL + F D + NRAE L+ LNP V VTS + +E D SF ++ V
Sbjct: 98 AWDLGTNFFLSEDDVVNKRNRAEAVLKHIAELNPYVHVTSSSVPFNETTDLSFLDKYQCV 157
Query: 471 CATGLKQEQFERINNACRDSNK--KFICGDVWGTYGYMFSDLVDHEYSXGDCT 623
T +K ++IN+ CR KFI DV G + +F D D E+ D T
Sbjct: 158 VLTEMKLPLQKKINDFCRSQCPPIKFISADVHGIWSRLFCDFGD-EFEVLDTT 209
Score = 41.9 bits (94), Expect = 0.002
Identities = 35/172 (20%), Positives = 72/172 (41%), Gaps = 11/172 (6%)
Frame = +3
Query: 93 VGNNEVELSEAEAEQYDRQIRLWGLDSQKRLRAAKVLIIGLSGLGAEIAKNVILTGVKS- 269
+G E E ++YD G ++L+ + ++G +G E+ KN L GV +
Sbjct: 428 LGKPECEEFLPRGDRYDALRACIGDTLCQKLQNLNIFLVGCGAIGCEMLKNFALLGVGTS 487
Query: 270 -----VCLLDNEKLKQIDLYSQFLCPPDKIGVNRAEGSLERARGLNPMVDVTSHTKGVDE 434
+ + D + +++ +L QFL P I ++ + + +N + + +H V
Sbjct: 488 KEKGMITVTDPDLIEKSNLNRQFLFRPHHIQKPKSYTAADATLKINSQIKIDAHLNKVCP 547
Query: 435 LP-----DSFFTEFDVVCATGLKQEQFERINNACRDSNKKFICGDVWGTYGY 575
D F+T+ DV+ E +++ C + + + GT G+
Sbjct: 548 TTETIYNDEFYTKQDVIITALDNVEARRYVDSRCLANLRPLLDSGTMGTKGH 599
>BC126486-1|AAI26487.1| 1052|Homo sapiens ubiquitin-activating
enzyme E1-like 2 protein.
Length = 1052
Score = 93.1 bits (221), Expect = 9e-19
Identities = 61/173 (35%), Positives = 90/173 (52%), Gaps = 5/173 (2%)
Frame = +3
Query: 120 EAEAEQYDRQIRLWGLDSQKRLRAAKVLIIGLSGLGAEIAKNVILTGVKSVCLLDNEKLK 299
E + Y RQ + G + +++ + V + G+ GLG EIAKN++L G+K+V + D EK +
Sbjct: 38 EIDDALYSRQRYVLGDTAMQKMAKSHVFLSGMGGLGLEIAKNLVLAGIKAVTIHDTEKCQ 97
Query: 300 QIDLYSQFLCPPDKI--GVNRAEGSLERARGLNPMVDVTSHTKGVDELPD-SFFTEFDVV 470
DL + F D + NRAE L+ LNP V VTS + +E D SF ++ V
Sbjct: 98 AWDLGTNFFLSEDDVVNKRNRAEAVLKHIAELNPYVHVTSSSVPFNETTDLSFLDKYQCV 157
Query: 471 CATGLKQEQFERINNACRDSNK--KFICGDVWGTYGYMFSDLVDHEYSXGDCT 623
T +K ++IN+ CR KFI DV G + +F D D E+ D T
Sbjct: 158 VLTEMKLPLQKKINDFCRSQCPPIKFISADVHGIWSRLFCDFGD-EFEVLDTT 209
Score = 41.9 bits (94), Expect = 0.002
Identities = 35/172 (20%), Positives = 72/172 (41%), Gaps = 11/172 (6%)
Frame = +3
Query: 93 VGNNEVELSEAEAEQYDRQIRLWGLDSQKRLRAAKVLIIGLSGLGAEIAKNVILTGVKS- 269
+G E E ++YD G ++L+ + ++G +G E+ KN L GV +
Sbjct: 428 LGKPECEEFLPRGDRYDALRACIGDTLCQKLQNLNIFLVGCGAIGCEMLKNFALLGVGTS 487
Query: 270 -----VCLLDNEKLKQIDLYSQFLCPPDKIGVNRAEGSLERARGLNPMVDVTSHTKGVDE 434
+ + D + +++ +L QFL P I ++ + + +N + + +H V
Sbjct: 488 KEKGMITVTDPDLIEKSNLNRQFLFRPHHIQKPKSYTAADATLKINSQIKIDAHLNKVCP 547
Query: 435 LP-----DSFFTEFDVVCATGLKQEQFERINNACRDSNKKFICGDVWGTYGY 575
D F+T+ DV+ E +++ C + + + GT G+
Sbjct: 548 TTETIYNDEFYTKQDVIITALDNVEARRYVDSRCLANLRPLLDSGTMGTKGH 599
>BC126484-1|AAI26485.1| 1052|Homo sapiens ubiquitin-activating
enzyme E1-like 2 protein.
Length = 1052
Score = 93.1 bits (221), Expect = 9e-19
Identities = 61/173 (35%), Positives = 90/173 (52%), Gaps = 5/173 (2%)
Frame = +3
Query: 120 EAEAEQYDRQIRLWGLDSQKRLRAAKVLIIGLSGLGAEIAKNVILTGVKSVCLLDNEKLK 299
E + Y RQ + G + +++ + V + G+ GLG EIAKN++L G+K+V + D EK +
Sbjct: 38 EIDDALYSRQRYVLGDTAMQKMAKSHVFLSGMGGLGLEIAKNLVLAGIKAVTIHDTEKCQ 97
Query: 300 QIDLYSQFLCPPDKI--GVNRAEGSLERARGLNPMVDVTSHTKGVDELPD-SFFTEFDVV 470
DL + F D + NRAE L+ LNP V VTS + +E D SF ++ V
Sbjct: 98 AWDLGTNFFLSEDDVVNKRNRAEAVLKHIAELNPYVHVTSSSVPFNETTDLSFLDKYQCV 157
Query: 471 CATGLKQEQFERINNACRDSNK--KFICGDVWGTYGYMFSDLVDHEYSXGDCT 623
T +K ++IN+ CR KFI DV G + +F D D E+ D T
Sbjct: 158 VLTEMKLPLQKKINDFCRSQCPPIKFISADVHGIWSRLFCDFGD-EFEVLDTT 209
Score = 41.9 bits (94), Expect = 0.002
Identities = 35/172 (20%), Positives = 72/172 (41%), Gaps = 11/172 (6%)
Frame = +3
Query: 93 VGNNEVELSEAEAEQYDRQIRLWGLDSQKRLRAAKVLIIGLSGLGAEIAKNVILTGVKS- 269
+G E E ++YD G ++L+ + ++G +G E+ KN L GV +
Sbjct: 428 LGKPECEEFLPRGDRYDALRACIGDTLCQKLQNLNIFLVGCGAIGCEMLKNFALLGVGTS 487
Query: 270 -----VCLLDNEKLKQIDLYSQFLCPPDKIGVNRAEGSLERARGLNPMVDVTSHTKGVDE 434
+ + D + +++ +L QFL P I ++ + + +N + + +H V
Sbjct: 488 KEKGMITVTDPDLIEKSNLNRQFLFRPHHIQKPKSYTAADATLKINSQIKIDAHLNKVCP 547
Query: 435 LP-----DSFFTEFDVVCATGLKQEQFERINNACRDSNKKFICGDVWGTYGY 575
D F+T+ DV+ E +++ C + + + GT G+
Sbjct: 548 TTETIYNDEFYTKQDVIITALDNVEARRYVDSRCLANLRPLLDSGTMGTKGH 599
>BC031637-1|AAH31637.1| 389|Homo sapiens UBE1L2 protein protein.
Length = 389
Score = 93.1 bits (221), Expect = 9e-19
Identities = 61/173 (35%), Positives = 90/173 (52%), Gaps = 5/173 (2%)
Frame = +3
Query: 120 EAEAEQYDRQIRLWGLDSQKRLRAAKVLIIGLSGLGAEIAKNVILTGVKSVCLLDNEKLK 299
E + Y RQ + G + +++ + V + G+ GLG EIAKN++L G+K+V + D EK +
Sbjct: 38 EIDDALYSRQRYVLGDTAMQKMAKSHVFLSGMGGLGLEIAKNLVLAGIKAVTIHDTEKCQ 97
Query: 300 QIDLYSQFLCPPDKI--GVNRAEGSLERARGLNPMVDVTSHTKGVDELPD-SFFTEFDVV 470
DL + F D + NRAE L+ LNP V VTS + +E D SF ++ V
Sbjct: 98 AWDLGTNFFLSEDDVVNKRNRAEAVLKHIAELNPYVHVTSSSVPFNETTDLSFLDKYQCV 157
Query: 471 CATGLKQEQFERINNACRDSNK--KFICGDVWGTYGYMFSDLVDHEYSXGDCT 623
T +K ++IN+ CR KFI DV G + +F D D E+ D T
Sbjct: 158 VLTEMKLPLQKKINDFCRSQCPPIKFISADVHGIWSRLFCDFGD-EFEVLDTT 209
>AL832458-1|CAD89959.1| 1052|Homo sapiens hypothetical protein
protein.
Length = 1052
Score = 93.1 bits (221), Expect = 9e-19
Identities = 61/173 (35%), Positives = 90/173 (52%), Gaps = 5/173 (2%)
Frame = +3
Query: 120 EAEAEQYDRQIRLWGLDSQKRLRAAKVLIIGLSGLGAEIAKNVILTGVKSVCLLDNEKLK 299
E + Y RQ + G + +++ + V + G+ GLG EIAKN++L G+K+V + D EK +
Sbjct: 38 EIDDALYSRQRYVLGDTAMQKMAKSHVFLSGMGGLGLEIAKNLVLAGIKAVTIHDTEKCQ 97
Query: 300 QIDLYSQFLCPPDKI--GVNRAEGSLERARGLNPMVDVTSHTKGVDELPD-SFFTEFDVV 470
DL + F D + NRAE L+ LNP V VTS + +E D SF ++ V
Sbjct: 98 AWDLGTNFFLSEDDVVNKRNRAEAVLKHIAELNPYVHVTSSSVPFNETTDLSFLDKYQCV 157
Query: 471 CATGLKQEQFERINNACRDSNK--KFICGDVWGTYGYMFSDLVDHEYSXGDCT 623
T +K ++IN+ CR KFI DV G + +F D D E+ D T
Sbjct: 158 VLTEMKLPLQKKINDFCRSQCPPIKFISADVHGIWSRLFCDFGD-EFEVLDTT 209
Score = 41.9 bits (94), Expect = 0.002
Identities = 35/172 (20%), Positives = 72/172 (41%), Gaps = 11/172 (6%)
Frame = +3
Query: 93 VGNNEVELSEAEAEQYDRQIRLWGLDSQKRLRAAKVLIIGLSGLGAEIAKNVILTGVKS- 269
+G E E ++YD G ++L+ + ++G +G E+ KN L GV +
Sbjct: 428 LGKPECEEFLPRGDRYDALRACIGDTLCQKLQNLNIFLVGCGAIGCEMLKNFALLGVGTS 487
Query: 270 -----VCLLDNEKLKQIDLYSQFLCPPDKIGVNRAEGSLERARGLNPMVDVTSHTKGVDE 434
+ + D + +++ +L QFL P I ++ + + +N + + +H V
Sbjct: 488 KEKGMITVTDPDLIEKSNLNRQFLFRPHHIQKPKSYTAADATLKINSQIKIDAHLNKVCP 547
Query: 435 LP-----DSFFTEFDVVCATGLKQEQFERINNACRDSNKKFICGDVWGTYGY 575
D F+T+ DV+ E +++ C + + + GT G+
Sbjct: 548 TTETIYNDEFYTKQDVIITALDNVEARRYVDSRCLANLRPLLDSGTMGTKGH 599
>AB014773-1|BAB19785.1| 1052|Homo sapiens MOP-4 protein.
Length = 1052
Score = 93.1 bits (221), Expect = 9e-19
Identities = 61/173 (35%), Positives = 90/173 (52%), Gaps = 5/173 (2%)
Frame = +3
Query: 120 EAEAEQYDRQIRLWGLDSQKRLRAAKVLIIGLSGLGAEIAKNVILTGVKSVCLLDNEKLK 299
E + Y RQ + G + +++ + V + G+ GLG EIAKN++L G+K+V + D EK +
Sbjct: 38 EIDDALYSRQRYVLGDTAMQKMAKSHVFLSGMGGLGLEIAKNLVLAGIKAVTIHDTEKCQ 97
Query: 300 QIDLYSQFLCPPDKI--GVNRAEGSLERARGLNPMVDVTSHTKGVDELPD-SFFTEFDVV 470
DL + F D + NRAE L+ LNP V VTS + +E D SF ++ V
Sbjct: 98 AWDLGTNFFLSEDDVVNKRNRAEAVLKHIAELNPYVHVTSSSVPFNETTDLSFLDKYQCV 157
Query: 471 CATGLKQEQFERINNACRDSNK--KFICGDVWGTYGYMFSDLVDHEYSXGDCT 623
T +K ++IN+ CR KFI DV G + +F D D E+ D T
Sbjct: 158 VLTEMKLPLQKKINDFCRSQCPPIKFISADVHGIWSRLFCDFGD-EFEVLDTT 209
Score = 41.9 bits (94), Expect = 0.002
Identities = 35/172 (20%), Positives = 72/172 (41%), Gaps = 11/172 (6%)
Frame = +3
Query: 93 VGNNEVELSEAEAEQYDRQIRLWGLDSQKRLRAAKVLIIGLSGLGAEIAKNVILTGVKS- 269
+G E E ++YD G ++L+ + ++G +G E+ KN L GV +
Sbjct: 428 LGKPECEEFLPRGDRYDALRACIGDTLCQKLQNLNIFLVGCGAIGCEMLKNFALLGVGTS 487
Query: 270 -----VCLLDNEKLKQIDLYSQFLCPPDKIGVNRAEGSLERARGLNPMVDVTSHTKGVDE 434
+ + D + +++ +L QFL P I ++ + + +N + + +H V
Sbjct: 488 KEKGMITVTDPDLIEKSNLNRQFLFRPHHIQKPKSYTAADATLKINSQIKIDAHLNKVCP 547
Query: 435 LP-----DSFFTEFDVVCATGLKQEQFERINNACRDSNKKFICGDVWGTYGY 575
D F+T+ DV+ E +++ C + + + GT G+
Sbjct: 548 TTETIYNDEFYTKQDVIITALDNVEARRYVDSRCLANLRPLLDSGTMGTKGH 599
>AK094969-1|BAC04463.1| 340|Homo sapiens protein ( Homo sapiens
cDNA FLJ37650 fis, clone BRHIP2000553, weakly similar to
UBIQUITIN-ACTIVATING ENZYME E1 1. ).
Length = 340
Score = 92.7 bits (220), Expect = 1e-18
Identities = 61/173 (35%), Positives = 90/173 (52%), Gaps = 5/173 (2%)
Frame = +3
Query: 120 EAEAEQYDRQIRLWGLDSQKRLRAAKVLIIGLSGLGAEIAKNVILTGVKSVCLLDNEKLK 299
E + Y RQ + G + +++ + V + G+ GLG EIAKN++L G+K+V + D EK +
Sbjct: 38 EIDDALYSRQRYVLGDTAMQKMAKSHVFLSGMGGLGLEIAKNLVLAGIKAVTIHDTEKCQ 97
Query: 300 QIDLYSQFLCPPDKI--GVNRAEGSLERARGLNPMVDVTSHTKGVDELPD-SFFTEFDVV 470
DL + F D + NRAE L+ LNP V VTS + +E D SF ++ V
Sbjct: 98 AWDLGTNFFLSEDDVVNKRNRAEAVLKHIAELNPYVHVTSSSVPFNETTDLSFLDKYQCV 157
Query: 471 CATGLKQEQFERINNACRDSNK--KFICGDVWGTYGYMFSDLVDHEYSXGDCT 623
T +K ++IN+ CR KFI DV G + +F D D E+ D T
Sbjct: 158 VLTEMKLPLQKKINDFCRSQCPPIKFISADVHGIWSRLFYDFGD-EFEVLDTT 209
>U50939-1|AAC50477.1| 534|Homo sapiens amyloid precursor
protein-binding protein 1 protein.
Length = 534
Score = 87.4 bits (207), Expect = 4e-17
Identities = 52/159 (32%), Positives = 81/159 (50%), Gaps = 3/159 (1%)
Frame = +3
Query: 132 EQYDRQIRLWGLDSQKRLRAAKVLIIGLSGLGAEIAKNVILTGVKSVCLLDNEKLKQIDL 311
++YDRQ+RLWG Q+ L +A V +I + G EI KN++L G+ S ++D ++ D
Sbjct: 11 QKYDRQLRLWGDHGQEALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQVSGEDA 70
Query: 312 YSQFLCPPDKIGVNRAEGSLERARGLNPMVDVTSHTKGVDELPD---SFFTEFDVVCATG 482
+ F IG NRAE ++E + LN V + + + L D SFF F VV AT
Sbjct: 71 GNNFFLQRSSIGKNRAEAAMEFLQELNSDVSGSFVEESPENLLDNDPSFFCRFTVVVATQ 130
Query: 483 LKQEQFERINNACRDSNKKFICGDVWGTYGYMFSDLVDH 599
L + R+ + +S + +G GYM + +H
Sbjct: 131 LPESTSLRLADVLWNSQIPLLICRTYGLVGYMRIIIKEH 169
>BC013301-1|AAH13301.1| 534|Homo sapiens amyloid beta precursor
protein binding protein 1 protein.
Length = 534
Score = 87.4 bits (207), Expect = 4e-17
Identities = 52/159 (32%), Positives = 81/159 (50%), Gaps = 3/159 (1%)
Frame = +3
Query: 132 EQYDRQIRLWGLDSQKRLRAAKVLIIGLSGLGAEIAKNVILTGVKSVCLLDNEKLKQIDL 311
++YDRQ+RLWG Q+ L +A V +I + G EI KN++L G+ S ++D ++ D
Sbjct: 11 QKYDRQLRLWGDHGQEALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQVSGEDA 70
Query: 312 YSQFLCPPDKIGVNRAEGSLERARGLNPMVDVTSHTKGVDELPD---SFFTEFDVVCATG 482
+ F IG NRAE ++E + LN V + + + L D SFF F VV AT
Sbjct: 71 GNNFFLQRSSIGKNRAEAAMEFLQELNSDVSGSFVEESPENLLDNDPSFFCRFTVVVATQ 130
Query: 483 LKQEQFERINNACRDSNKKFICGDVWGTYGYMFSDLVDH 599
L + R+ + +S + +G GYM + +H
Sbjct: 131 LPESTSLRLADVLWNSQIPLLICRTYGLVGYMRIIIKEH 169
>BC000480-1|AAH00480.1| 534|Homo sapiens amyloid beta precursor
protein binding protein 1 protein.
Length = 534
Score = 87.4 bits (207), Expect = 4e-17
Identities = 52/159 (32%), Positives = 81/159 (50%), Gaps = 3/159 (1%)
Frame = +3
Query: 132 EQYDRQIRLWGLDSQKRLRAAKVLIIGLSGLGAEIAKNVILTGVKSVCLLDNEKLKQIDL 311
++YDRQ+RLWG Q+ L +A V +I + G EI KN++L G+ S ++D ++ D
Sbjct: 11 QKYDRQLRLWGDHGQEALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQVSGEDA 70
Query: 312 YSQFLCPPDKIGVNRAEGSLERARGLNPMVDVTSHTKGVDELPD---SFFTEFDVVCATG 482
+ F IG NRAE ++E + LN V + + + L D SFF F VV AT
Sbjct: 71 GNNFFLQRSSIGKNRAEAAMEFLQELNSDVSGSFVEESPENLLDNDPSFFCRFTVVVATQ 130
Query: 483 LKQEQFERINNACRDSNKKFICGDVWGTYGYMFSDLVDH 599
L + R+ + +S + +G GYM + +H
Sbjct: 131 LPESTSLRLADVLWNSQIPLLICRTYGLVGYMRIIIKEH 169
>AY197612-1|AAP35030.1| 534|Homo sapiens protooncogene protein 1
protein.
Length = 534
Score = 87.4 bits (207), Expect = 4e-17
Identities = 52/159 (32%), Positives = 81/159 (50%), Gaps = 3/159 (1%)
Frame = +3
Query: 132 EQYDRQIRLWGLDSQKRLRAAKVLIIGLSGLGAEIAKNVILTGVKSVCLLDNEKLKQIDL 311
++YDRQ+RLWG Q+ L +A V +I + G EI KN++L G+ S ++D ++ D
Sbjct: 11 QKYDRQLRLWGDHGQEALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQVSGEDA 70
Query: 312 YSQFLCPPDKIGVNRAEGSLERARGLNPMVDVTSHTKGVDELPD---SFFTEFDVVCATG 482
+ F IG NRAE ++E + LN V + + + L D SFF F VV AT
Sbjct: 71 GNNFFLQRSSIGKNRAEAAMEFLQELNSDVSGSFVEESPENLLDNDPSFFCRFTVVVATQ 130
Query: 483 LKQEQFERINNACRDSNKKFICGDVWGTYGYMFSDLVDH 599
L + R+ + +S + +G GYM + +H
Sbjct: 131 LPESTSLRLADVLWNSQIPLLICRTYGLVGYMRIIIKEH 169
>AC004638-1|AAC23784.1| 534|Homo sapiens amyloid precursor
protein-binding protein 1 (APP-B1) protein.
Length = 534
Score = 87.4 bits (207), Expect = 4e-17
Identities = 52/159 (32%), Positives = 81/159 (50%), Gaps = 3/159 (1%)
Frame = +3
Query: 132 EQYDRQIRLWGLDSQKRLRAAKVLIIGLSGLGAEIAKNVILTGVKSVCLLDNEKLKQIDL 311
++YDRQ+RLWG Q+ L +A V +I + G EI KN++L G+ S ++D ++ D
Sbjct: 11 QKYDRQLRLWGDHGQEALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQVSGEDA 70
Query: 312 YSQFLCPPDKIGVNRAEGSLERARGLNPMVDVTSHTKGVDELPD---SFFTEFDVVCATG 482
+ F IG NRAE ++E + LN V + + + L D SFF F VV AT
Sbjct: 71 GNNFFLQRSSIGKNRAEAAMEFLQELNSDVSGSFVEESPENLLDNDPSFFCRFTVVVATQ 130
Query: 483 LKQEQFERINNACRDSNKKFICGDVWGTYGYMFSDLVDH 599
L + R+ + +S + +G GYM + +H
Sbjct: 131 LPESTSLRLADVLWNSQIPLLICRTYGLVGYMRIIIKEH 169
>AL513366-9|CAI41705.1| 173|Homo sapiens ubiquitin-activating
enzyme E1 (A1S9T and BN75 temperature sensitivity
compleme protein.
Length = 173
Score = 86.2 bits (204), Expect = 1e-16
Identities = 49/103 (47%), Positives = 65/103 (63%), Gaps = 2/103 (1%)
Frame = +3
Query: 117 SEAEAEQ--YDRQIRLWGLDSQKRLRAAKVLIIGLSGLGAEIAKNVILTGVKSVCLLDNE 290
SEA+ ++ Y RQ+ + G ++ KRL+ + VL+ GL GLG EIAKN+IL GVK+V L D
Sbjct: 60 SEADIDEGLYSRQLYVLGHEAMKRLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQG 119
Query: 291 KLKQIDLYSQFLCPPDKIGVNRAEGSLERARGLNPMVDVTSHT 419
+ DL SQF + IG NRAE S R LN V VT++T
Sbjct: 120 TAQWADLSSQFYLREEDIGKNRAEVSQPRLAELNSYVPVTAYT 162
>AL513366-7|CAI41703.1| 195|Homo sapiens ubiquitin-activating
enzyme E1 (A1S9T and BN75 temperature sensitivity
compleme protein.
Length = 195
Score = 81.0 bits (191), Expect = 4e-15
Identities = 47/99 (47%), Positives = 61/99 (61%), Gaps = 2/99 (2%)
Frame = +3
Query: 117 SEAEAEQ--YDRQIRLWGLDSQKRLRAAKVLIIGLSGLGAEIAKNVILTGVKSVCLLDNE 290
SEA+ ++ Y RQ+ + G ++ KRL+ + VL+ GL GLG EIAKN+IL GVK+V L D
Sbjct: 97 SEADIDEGLYSRQLYVLGHEAMKRLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQG 156
Query: 291 KLKQIDLYSQFLCPPDKIGVNRAEGSLERARGLNPMVDV 407
+ DL SQF + IG NRAE S R LN V V
Sbjct: 157 TAQWADLSSQFYLREEDIGKNRAEVSQPRLAELNSYVPV 195
>BC022853-1|AAH22853.1| 463|Homo sapiens ubiquitin-activating
enzyme E1C (UBA3 homolog, yeast) protein.
Length = 463
Score = 62.9 bits (146), Expect = 1e-09
Identities = 31/96 (32%), Positives = 52/96 (54%)
Frame = +3
Query: 183 LRAAKVLIIGLSGLGAEIAKNVILTGVKSVCLLDNEKLKQIDLYSQFLCPPDKIGVNRAE 362
L KVL+IG GLG E+ KN+ L+G + + ++D + + +L QFL P IG +AE
Sbjct: 67 LDTCKVLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQFLFRPKDIGRPKAE 126
Query: 363 GSLERARGLNPMVDVTSHTKGVDELPDSFFTEFDVV 470
+ E P +V H + + D+F+ +F ++
Sbjct: 127 VAAEFLNDRVPNCNVVPHFNKIQDFNDTFYRQFHII 162
>AF046024-1|AAC27648.1| 442|Homo sapiens UBA3 protein.
Length = 442
Score = 62.9 bits (146), Expect = 1e-09
Identities = 31/96 (32%), Positives = 52/96 (54%)
Frame = +3
Query: 183 LRAAKVLIIGLSGLGAEIAKNVILTGVKSVCLLDNEKLKQIDLYSQFLCPPDKIGVNRAE 362
L KVL+IG GLG E+ KN+ L+G + + ++D + + +L QFL P IG +AE
Sbjct: 46 LDTCKVLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQFLFRPKDIGRPKAE 105
Query: 363 GSLERARGLNPMVDVTSHTKGVDELPDSFFTEFDVV 470
+ E P +V H + + D+F+ +F ++
Sbjct: 106 VAAEFLNDRVPNCNVVPHFNKIQDFNDTFYRQFHII 141
>AB012190-1|BAA33144.1| 442|Homo sapiens Nedd8-activating enzyme
hUba3 protein.
Length = 442
Score = 62.9 bits (146), Expect = 1e-09
Identities = 31/96 (32%), Positives = 52/96 (54%)
Frame = +3
Query: 183 LRAAKVLIIGLSGLGAEIAKNVILTGVKSVCLLDNEKLKQIDLYSQFLCPPDKIGVNRAE 362
L KVL+IG GLG E+ KN+ L+G + + ++D + + +L QFL P IG +AE
Sbjct: 46 LDTCKVLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQFLFRPKDIGRPKAE 105
Query: 363 GSLERARGLNPMVDVTSHTKGVDELPDSFFTEFDVV 470
+ E P +V H + + D+F+ +F ++
Sbjct: 106 VAAEFLNDRVPNCNVVPHFNKIQDFNDTFYRQFHII 141
>CR533537-1|CAG38568.1| 463|Homo sapiens UBE1C protein.
Length = 463
Score = 62.1 bits (144), Expect = 2e-09
Identities = 31/96 (32%), Positives = 52/96 (54%)
Frame = +3
Query: 183 LRAAKVLIIGLSGLGAEIAKNVILTGVKSVCLLDNEKLKQIDLYSQFLCPPDKIGVNRAE 362
L KVL+IG GLG E+ KN+ L+G + + ++D + + +L QFL P IG +AE
Sbjct: 67 LDTCKVLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQFLFRPKDIGRPKAE 126
Query: 363 GSLERARGLNPMVDVTSHTKGVDELPDSFFTEFDVV 470
+ E P +V H + + D+F+ +F ++
Sbjct: 127 VAAEFLNDRVPNCNVVPHFYKIQDFNDTFYRQFHII 162
>X52897-1|CAA37078.1| 803|Homo sapiens protein ( Human A1S9 mRNA
for A1S9 protein of unknown function. ).
Length = 803
Score = 53.2 bits (122), Expect = 9e-07
Identities = 33/122 (27%), Positives = 59/122 (48%), Gaps = 10/122 (8%)
Frame = +3
Query: 135 QYDRQIRLWGLDSQKRLRAAKVLIIGLSGLGAEIAKNVILTGVK-----SVCLLDNEKLK 299
+YD Q+ ++G D Q++L K ++G +G E+ KN + G+ + + D + ++
Sbjct: 195 RYDGQVAVFGSDLQEKLGKQKYFLVGAGAIGCELLKNFAMIGLGCGEGGEIIVTDMDTIE 254
Query: 300 QIDLYSQFLCPPDKIGVNRAEGSLERARGLNPMVDVTSHTKGVDE-----LPDSFFTEFD 464
+ +L QFL P + +++ + R +NP + VTSH V D FF D
Sbjct: 255 KSNLNRQFLFRPWDVTKLKSDTAAAAVRQMNPHIRVTSHQNRVGPDTERIYDDDFFQNLD 314
Query: 465 VV 470
V
Sbjct: 315 GV 316
>U35832-1|AAC99992.1| 640|Homo sapiens anthracycline-associated
resistance ARX protein.
Length = 640
Score = 52.4 bits (120), Expect = 1e-06
Identities = 34/131 (25%), Positives = 63/131 (48%), Gaps = 3/131 (2%)
Frame = +3
Query: 195 KVLIIGLSGLGAEIAKNVILTGVKSVCLLDNEKLKQIDLYSQFLCPPDKIGVNRAEGSLE 374
+VL++G G+G E+ KN++LTG + L+D + + +L QFL +G ++A+ + E
Sbjct: 19 RVLVVGAGGIGCELLKNLVLTGFSHIDLIDLDTIDVSNLNRQFLFQKKHVGRSKAQVAKE 78
Query: 375 RARGLNPMVDVTSHTKGVDELPD---SFFTEFDVVCATGLKQEQFERINNACRDSNKKFI 545
P ++ ++ + PD FF +F +V + +N C ++ I
Sbjct: 79 SVLQFYPKANIVAYHDSIMN-PDYNVEFFRQFILVMNALDNRAARNHVNRMCLAADVPLI 137
Query: 546 CGDVWGTYGYM 578
GT GY+
Sbjct: 138 ES---GTAGYL 145
>CR456756-1|CAG33037.1| 640|Homo sapiens UBA2 protein.
Length = 640
Score = 52.4 bits (120), Expect = 1e-06
Identities = 34/131 (25%), Positives = 63/131 (48%), Gaps = 3/131 (2%)
Frame = +3
Query: 195 KVLIIGLSGLGAEIAKNVILTGVKSVCLLDNEKLKQIDLYSQFLCPPDKIGVNRAEGSLE 374
+VL++G G+G E+ KN++LTG + L+D + + +L QFL +G ++A+ + E
Sbjct: 19 RVLVVGAGGIGCELLKNLVLTGFSHIDLIDLDTIDVSNLNRQFLFQKKHVGRSKAQVAKE 78
Query: 375 RARGLNPMVDVTSHTKGVDELPD---SFFTEFDVVCATGLKQEQFERINNACRDSNKKFI 545
P ++ ++ + PD FF +F +V + +N C ++ I
Sbjct: 79 SVLQFYPKANIVAYHDSIMN-PDYNVEFFRQFILVMNALDNRAARNHVNRMCLAADVPLI 137
Query: 546 CGDVWGTYGYM 578
GT GY+
Sbjct: 138 ES---GTAGYL 145
>BT009781-1|AAP88783.1| 640|Homo sapiens SUMO-1 activating enzyme
subunit 2 protein.
Length = 640
Score = 52.4 bits (120), Expect = 1e-06
Identities = 34/131 (25%), Positives = 63/131 (48%), Gaps = 3/131 (2%)
Frame = +3
Query: 195 KVLIIGLSGLGAEIAKNVILTGVKSVCLLDNEKLKQIDLYSQFLCPPDKIGVNRAEGSLE 374
+VL++G G+G E+ KN++LTG + L+D + + +L QFL +G ++A+ + E
Sbjct: 19 RVLVVGAGGIGCELLKNLVLTGFSHIDLIDLDTIDVSNLNRQFLFQKKHVGRSKAQVAKE 78
Query: 375 RARGLNPMVDVTSHTKGVDELPD---SFFTEFDVVCATGLKQEQFERINNACRDSNKKFI 545
P ++ ++ + PD FF +F +V + +N C ++ I
Sbjct: 79 SVLQFYPKANIVAYHDSIMN-PDYNVEFFRQFILVMNALDNRAARNHVNRMCLAADVPLI 137
Query: 546 CGDVWGTYGYM 578
GT GY+
Sbjct: 138 ES---GTAGYL 145
>BC003153-1|AAH03153.1| 640|Homo sapiens SUMO1 activating enzyme
subunit 2 protein.
Length = 640
Score = 52.4 bits (120), Expect = 1e-06
Identities = 34/131 (25%), Positives = 63/131 (48%), Gaps = 3/131 (2%)
Frame = +3
Query: 195 KVLIIGLSGLGAEIAKNVILTGVKSVCLLDNEKLKQIDLYSQFLCPPDKIGVNRAEGSLE 374
+VL++G G+G E+ KN++LTG + L+D + + +L QFL +G ++A+ + E
Sbjct: 19 RVLVVGAGGIGCELLKNLVLTGFSHIDLIDLDTIDVSNLNRQFLFQKKHVGRSKAQVAKE 78
Query: 375 RARGLNPMVDVTSHTKGVDELPD---SFFTEFDVVCATGLKQEQFERINNACRDSNKKFI 545
P ++ ++ + PD FF +F +V + +N C ++ I
Sbjct: 79 SVLQFYPKANIVAYHDSIMN-PDYNVEFFRQFILVMNALDNRAARNHVNRMCLAADVPLI 137
Query: 546 CGDVWGTYGYM 578
GT GY+
Sbjct: 138 ES---GTAGYL 145
>AF110957-1|AAD24434.1| 640|Homo sapiens SUMO-1 activating enzyme
subunit 2 protein.
Length = 640
Score = 52.4 bits (120), Expect = 1e-06
Identities = 34/131 (25%), Positives = 63/131 (48%), Gaps = 3/131 (2%)
Frame = +3
Query: 195 KVLIIGLSGLGAEIAKNVILTGVKSVCLLDNEKLKQIDLYSQFLCPPDKIGVNRAEGSLE 374
+VL++G G+G E+ KN++LTG + L+D + + +L QFL +G ++A+ + E
Sbjct: 19 RVLVVGAGGIGCELLKNLVLTGFSHIDLIDLDTIDVSNLNRQFLFQKKHVGRSKAQVAKE 78
Query: 375 RARGLNPMVDVTSHTKGVDELPD---SFFTEFDVVCATGLKQEQFERINNACRDSNKKFI 545
P ++ ++ + PD FF +F +V + +N C ++ I
Sbjct: 79 SVLQFYPKANIVAYHDSIMN-PDYNVEFFRQFILVMNALDNRAARNHVNRMCLAADVPLI 137
Query: 546 CGDVWGTYGYM 578
GT GY+
Sbjct: 138 ES---GTAGYL 145
>AF090384-1|AAD12784.1| 640|Homo sapiens SUMO-1-activating enzyme
E1 C subunit protein.
Length = 640
Score = 52.4 bits (120), Expect = 1e-06
Identities = 34/131 (25%), Positives = 63/131 (48%), Gaps = 3/131 (2%)
Frame = +3
Query: 195 KVLIIGLSGLGAEIAKNVILTGVKSVCLLDNEKLKQIDLYSQFLCPPDKIGVNRAEGSLE 374
+VL++G G+G E+ KN++LTG + L+D + + +L QFL +G ++A+ + E
Sbjct: 19 RVLVVGAGGIGCELLKNLVLTGFSHIDLIDLDTIDVSNLNRQFLFQKKHVGRSKAQVAKE 78
Query: 375 RARGLNPMVDVTSHTKGVDELPD---SFFTEFDVVCATGLKQEQFERINNACRDSNKKFI 545
P ++ ++ + PD FF +F +V + +N C ++ I
Sbjct: 79 SVLQFYPKANIVAYHDSIMN-PDYNVEFFRQFILVMNALDNRAARNHVNRMCLAADVPLI 137
Query: 546 CGDVWGTYGYM 578
GT GY+
Sbjct: 138 ES---GTAGYL 145
>AF079566-1|AAD23914.1| 640|Homo sapiens ubiquitin-like protein
activating enzyme protein.
Length = 640
Score = 52.4 bits (120), Expect = 1e-06
Identities = 34/131 (25%), Positives = 63/131 (48%), Gaps = 3/131 (2%)
Frame = +3
Query: 195 KVLIIGLSGLGAEIAKNVILTGVKSVCLLDNEKLKQIDLYSQFLCPPDKIGVNRAEGSLE 374
+VL++G G+G E+ KN++LTG + L+D + + +L QFL +G ++A+ + E
Sbjct: 19 RVLVVGAGGIGCELLKNLVLTGFSHIDLIDLDTIDVSNLNRQFLFQKKHVGRSKAQVAKE 78
Query: 375 RARGLNPMVDVTSHTKGVDELPD---SFFTEFDVVCATGLKQEQFERINNACRDSNKKFI 545
P ++ ++ + PD FF +F +V + +N C ++ I
Sbjct: 79 SVLQFYPKANIVAYHDSIMN-PDYNVEFFRQFILVMNALDNRAARNHVNRMCLAADVPLI 137
Query: 546 CGDVWGTYGYM 578
GT GY+
Sbjct: 138 ES---GTAGYL 145
>BC015939-1|AAH15939.1| 460|Homo sapiens molybdenum cofactor
synthesis 3 protein.
Length = 460
Score = 48.8 bits (111), Expect = 2e-05
Identities = 40/139 (28%), Positives = 62/139 (44%), Gaps = 3/139 (2%)
Frame = +3
Query: 114 LSEAEAEQYDRQIRL--WGLDSQKRLRAAKVLIIGLSGLGAEIAKNVILTGVKSVCLLDN 287
LS E +Y RQ+ L G+ Q RL A VLI+G GLG +A+ + GV + L+D
Sbjct: 55 LSRDEILRYSRQLVLPELGVHGQLRLGTACVLIVGCGGLGCPLAQYLAAAGVGRLGLVDY 114
Query: 288 EKLKQIDLYSQFLCPPDKIGVNRAEGSLERARGLNPMVDVTSHTKGVDELPD-SFFTEFD 464
+ ++ +L Q L G +A + R LN V+ +T+ + +D
Sbjct: 115 DVVEMSNLARQVLHGEALAGQAKAFSAAASLRRLNSAVECVPYTQALTPATALDLVRRYD 174
Query: 465 VVCATGLKQEQFERINNAC 521
VV +N+AC
Sbjct: 175 VVADCSDNVPTRYLVNDAC 193
>AL034553-7|CAB53750.1| 460|Homo sapiens molybdenum cofactor
synthesis 3 protein.
Length = 460
Score = 48.8 bits (111), Expect = 2e-05
Identities = 40/139 (28%), Positives = 62/139 (44%), Gaps = 3/139 (2%)
Frame = +3
Query: 114 LSEAEAEQYDRQIRL--WGLDSQKRLRAAKVLIIGLSGLGAEIAKNVILTGVKSVCLLDN 287
LS E +Y RQ+ L G+ Q RL A VLI+G GLG +A+ + GV + L+D
Sbjct: 55 LSRDEILRYSRQLVLPELGVHGQLRLGTACVLIVGCGGLGCPLAQYLAAAGVGRLGLVDY 114
Query: 288 EKLKQIDLYSQFLCPPDKIGVNRAEGSLERARGLNPMVDVTSHTKGVDELPD-SFFTEFD 464
+ ++ +L Q L G +A + R LN V+ +T+ + +D
Sbjct: 115 DVVEMSNLARQVLHGEALAGQAKAFSAAASLRRLNSAVECVPYTQALTPATALDLVRRYD 174
Query: 465 VVCATGLKQEQFERINNAC 521
VV +N+AC
Sbjct: 175 VVADCSDNVPTRYLVNDAC 193
>AF102544-1|AAC72412.1| 460|Homo sapiens molybdopterin synthase
sulfurylase protein.
Length = 460
Score = 48.8 bits (111), Expect = 2e-05
Identities = 40/139 (28%), Positives = 62/139 (44%), Gaps = 3/139 (2%)
Frame = +3
Query: 114 LSEAEAEQYDRQIRL--WGLDSQKRLRAAKVLIIGLSGLGAEIAKNVILTGVKSVCLLDN 287
LS E +Y RQ+ L G+ Q RL A VLI+G GLG +A+ + GV + L+D
Sbjct: 55 LSRDEILRYSRQLVLPELGVHGQLRLGTACVLIVGCGGLGCPLAQYLAAAGVGRLGLVDY 114
Query: 288 EKLKQIDLYSQFLCPPDKIGVNRAEGSLERARGLNPMVDVTSHTKGVDELPD-SFFTEFD 464
+ ++ +L Q L G +A + R LN V+ +T+ + +D
Sbjct: 115 DVVEMSNLARQVLHGEALAGQAKAFSAAASLRRLNSAVECVPYTQALTPATALDLVRRYD 174
Query: 465 VVCATGLKQEQFERINNAC 521
VV +N+AC
Sbjct: 175 VVADCSDNVPTRYLVNDAC 193
>AC096720-2|AAY40999.1| 787|Homo sapiens unknown protein.
Length = 787
Score = 41.9 bits (94), Expect = 0.002
Identities = 35/172 (20%), Positives = 72/172 (41%), Gaps = 11/172 (6%)
Frame = +3
Query: 93 VGNNEVELSEAEAEQYDRQIRLWGLDSQKRLRAAKVLIIGLSGLGAEIAKNVILTGVKS- 269
+G E E ++YD G ++L+ + ++G +G E+ KN L GV +
Sbjct: 163 LGKPECEEFLPRGDRYDALRACIGDTLCQKLQNLNIFLVGCGAIGCEMLKNFALLGVGTS 222
Query: 270 -----VCLLDNEKLKQIDLYSQFLCPPDKIGVNRAEGSLERARGLNPMVDVTSHTKGVDE 434
+ + D + +++ +L QFL P I ++ + + +N + + +H V
Sbjct: 223 KEKGMITVTDPDLIEKSNLNRQFLFRPHHIQKPKSYTAADATLKINSQIKIDAHLNKVCP 282
Query: 435 LP-----DSFFTEFDVVCATGLKQEQFERINNACRDSNKKFICGDVWGTYGY 575
D F+T+ DV+ E +++ C + + + GT G+
Sbjct: 283 TTETIYNDEFYTKQDVIITALDNVEARRYVDSRCLANLRPLLDSGTMGTKGH 334
>BC009737-1|AAH09737.1| 404|Homo sapiens ubiquitin-activating
enzyme E1-domain containing 1 protein.
Length = 404
Score = 39.9 bits (89), Expect = 0.009
Identities = 26/126 (20%), Positives = 62/126 (49%)
Frame = +3
Query: 153 RLWGLDSQKRLRAAKVLIIGLSGLGAEIAKNVILTGVKSVCLLDNEKLKQIDLYSQFLCP 332
R+ + +++R V I+G+ G+G+ A+ + G+ + L D +K++ ++ F
Sbjct: 61 RMGIVSDYEKIRTFAVAIVGVGGVGSVTAEMLTRCGIGKLLLFDYDKVELANMNRLFF-Q 119
Query: 333 PDKIGVNRAEGSLERARGLNPMVDVTSHTKGVDELPDSFFTEFDVVCATGLKQEQFERIN 512
P + G+++ + + R +NP V H + + ++F D + GL++ + +
Sbjct: 120 PHQAGLSKVQAAEHTLRNINPDVLFEVHNYNITTV-ENFQHFMDRISNGGLEEGKPVDLV 178
Query: 513 NACRDS 530
+C D+
Sbjct: 179 LSCVDN 184
>AY253672-1|AAP79600.1| 404|Homo sapiens ThiFP1 protein.
Length = 404
Score = 39.9 bits (89), Expect = 0.009
Identities = 26/126 (20%), Positives = 62/126 (49%)
Frame = +3
Query: 153 RLWGLDSQKRLRAAKVLIIGLSGLGAEIAKNVILTGVKSVCLLDNEKLKQIDLYSQFLCP 332
R+ + +++R V I+G+ G+G+ A+ + G+ + L D +K++ ++ F
Sbjct: 61 RMGIVSDYEKIRTFAVAIVGVGGVGSVTAEMLTRCGIGKLLLFDYDKVELANMNRLFF-Q 119
Query: 333 PDKIGVNRAEGSLERARGLNPMVDVTSHTKGVDELPDSFFTEFDVVCATGLKQEQFERIN 512
P + G+++ + + R +NP V H + + ++F D + GL++ + +
Sbjct: 120 PHQAGLSKVQAAEHTLRNINPDVLFEVHNYNITTV-ENFQHFMDRISNGGLEEGKPVDLV 178
Query: 513 NACRDS 530
+C D+
Sbjct: 179 LSCVDN 184
>AL136757-1|CAB66691.1| 404|Homo sapiens hypothetical protein
protein.
Length = 404
Score = 39.9 bits (89), Expect = 0.009
Identities = 26/126 (20%), Positives = 62/126 (49%)
Frame = +3
Query: 153 RLWGLDSQKRLRAAKVLIIGLSGLGAEIAKNVILTGVKSVCLLDNEKLKQIDLYSQFLCP 332
R+ + +++R V I+G+ G+G+ A+ + G+ + L D +K++ ++ F
Sbjct: 61 RMGIVSDYEKIRTFAVAIVGVGGVGSVTAEMLTRCGIGKLLLFDYDKVELANMNRLFF-Q 119
Query: 333 PDKIGVNRAEGSLERARGLNPMVDVTSHTKGVDELPDSFFTEFDVVCATGLKQEQFERIN 512
P + G+++ + + R +NP V H + + ++F D + GL++ + +
Sbjct: 120 PHQAGLSKVQAAEHTLRNINPDVLFEVHNYNITTV-ENFQHFMDRISNGGLEEGKPVDLV 178
Query: 513 NACRDS 530
+C D+
Sbjct: 179 LSCVDN 184
>AK027563-1|BAB55199.1| 348|Homo sapiens protein ( Homo sapiens
cDNA FLJ14657 fis, clone NT2RP2002442, weakly similar to
HESA PROTEIN. ).
Length = 348
Score = 39.9 bits (89), Expect = 0.009
Identities = 26/126 (20%), Positives = 62/126 (49%)
Frame = +3
Query: 153 RLWGLDSQKRLRAAKVLIIGLSGLGAEIAKNVILTGVKSVCLLDNEKLKQIDLYSQFLCP 332
R+ + +++R V I+G+ G+G+ A+ + G+ + L D +K++ ++ F
Sbjct: 5 RMGIVSDYEKIRTFAVAIVGVGGVGSVTAEMLTRCGIGKLLLFDYDKVELANMNRLFF-Q 63
Query: 333 PDKIGVNRAEGSLERARGLNPMVDVTSHTKGVDELPDSFFTEFDVVCATGLKQEQFERIN 512
P + G+++ + + R +NP V H + + ++F D + GL++ + +
Sbjct: 64 PHQAGLSKVQAAEHTLRNINPDVLFEVHNYNITTV-ENFQHFMDRISNGGLEEGKPVDLV 122
Query: 513 NACRDS 530
+C D+
Sbjct: 123 LSCVDN 128
>AK026904-1|BAB15587.1| 404|Homo sapiens protein ( Homo sapiens
cDNA: FLJ23251 fis, clone COL04590. ).
Length = 404
Score = 39.9 bits (89), Expect = 0.009
Identities = 26/126 (20%), Positives = 62/126 (49%)
Frame = +3
Query: 153 RLWGLDSQKRLRAAKVLIIGLSGLGAEIAKNVILTGVKSVCLLDNEKLKQIDLYSQFLCP 332
R+ + +++R V I+G+ G+G+ A+ + G+ + L D +K++ ++ F
Sbjct: 61 RMGIVSDYEKIRTFAVAIVGVGGVGSVTAEMLTRCGIGKLLLFDYDKVELANMNRLFF-Q 119
Query: 333 PDKIGVNRAEGSLERARGLNPMVDVTSHTKGVDELPDSFFTEFDVVCATGLKQEQFERIN 512
P + G+++ + + R +NP V H + + ++F D + GL++ + +
Sbjct: 120 PHQAGLSKVQAAEHTLRNINPDVLFEVHNYNITTV-ENFQHFMDRISNGGLEEGKPVDLV 178
Query: 513 NACRDS 530
+C D+
Sbjct: 179 LSCVDN 184
>AB154406-1|BAD15375.1| 404|Homo sapiens Ubiquitin activating
enzyme protein.
Length = 404
Score = 39.9 bits (89), Expect = 0.009
Identities = 26/126 (20%), Positives = 62/126 (49%)
Frame = +3
Query: 153 RLWGLDSQKRLRAAKVLIIGLSGLGAEIAKNVILTGVKSVCLLDNEKLKQIDLYSQFLCP 332
R+ + +++R V I+G+ G+G+ A+ + G+ + L D +K++ ++ F
Sbjct: 61 RMGIVSDYEKIRTFAVAIVGVGGVGSVTAEMLTRCGIGKLLLFDYDKVELANMNRLFF-Q 119
Query: 333 PDKIGVNRAEGSLERARGLNPMVDVTSHTKGVDELPDSFFTEFDVVCATGLKQEQFERIN 512
P + G+++ + + R +NP V H + + ++F D + GL++ + +
Sbjct: 120 PHQAGLSKVQAAEHTLRNINPDVLFEVHNYNITTV-ENFQHFMDRISNGGLEEGKPVDLV 178
Query: 513 NACRDS 530
+C D+
Sbjct: 179 LSCVDN 184
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 91,443,256
Number of Sequences: 237096
Number of extensions: 1773972
Number of successful extensions: 4704
Number of sequences better than 10.0: 55
Number of HSP's better than 10.0 without gapping: 4547
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4688
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8063224416
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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