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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= brP-0442
         (750 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

J05262-1|AAA52423.1|  353|Homo sapiens FDPS protein.                  103   9e-22
D14697-1|BAA03523.2|  420|Homo sapiens KIAA1293 protein.              102   1e-21
BC010004-1|AAH10004.1|  419|Homo sapiens farnesyl diphosphate sy...   102   1e-21
AL139410-1|CAI12715.1|  419|Homo sapiens farnesyl diphosphate sy...   102   1e-21
M29863-1|AAA35820.1|  346|Homo sapiens protein ( Human farnesyl ...   102   2e-21
Z47055-1|CAA87327.1|  348|Homo sapiens farnesyl pyrophosphate sy...    97   4e-20
BC050292-1|AAH50292.1|  298|Homo sapiens LOC619190 protein protein.    76   2e-13
AL139333-5|CAI15284.1| 2369|Homo sapiens dopey family member 1 p...    38   0.039
AL139333-4|CAM21599.1| 2465|Homo sapiens dopey family member 1 p...    38   0.039
AL121716-2|CAI42426.1| 2369|Homo sapiens dopey family member 1 p...    38   0.039
AL121716-1|CAI42425.2| 2465|Homo sapiens dopey family member 1 p...    38   0.039
BC063635-1|AAH63635.1|  306|Homo sapiens PDSS1 protein protein.        30   7.7  
BC049211-1|AAH49211.1|  414|Homo sapiens PDSS1 protein protein.        30   7.7  
AL390961-9|CAI17280.1|  415|Homo sapiens trans-prenyltransferase...    30   7.7  
AB210838-1|BAE48216.1|  415|Homo sapiens subunit 1 of decaprenyl...    30   7.7  
AB209763-1|BAD93000.1|  297|Homo sapiens trans-prenyltransferase...    30   7.7  

>J05262-1|AAA52423.1|  353|Homo sapiens FDPS protein.
          Length = 353

 Score =  103 bits (246), Expect = 9e-22
 Identities = 47/116 (40%), Positives = 72/116 (62%), Gaps = 3/116 (2%)
 Frame = +3

Query: 333 PQIGDW---LKKMLHYNLVGGKHTRXITTVIXYKTIEKPEKVTEHTLKMACKLGWCVEMF 503
           P+IGD    LK++L YN +GGK+ R +T V+ ++ + +P K    +L+ A  +GWCVE+ 
Sbjct: 36  PEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELL 95

Query: 504 QAYCIVLDDIMDGSSVRRGMPCWYRRPEVGITCXFNDSLXIHSXLXEFLKTNXXDQ 671
           QA+ +V DDIMD S  RRG  CWY++P VG+    ND+  + + +   LK    +Q
Sbjct: 96  QAFFLVADDIMDSSLTRRGQTCWYQKPGVGLDA-INDANLLEACIYRLLKLYCREQ 150


>D14697-1|BAA03523.2|  420|Homo sapiens KIAA1293 protein.
          Length = 420

 Score =  102 bits (245), Expect = 1e-21
 Identities = 55/166 (33%), Positives = 90/166 (54%), Gaps = 3/166 (1%)
 Frame = +3

Query: 183 WPQLIRYKNNSAXMTTASKNLEIINEKKMFDDLLPEVIMTLQNKSKLSEVPQIGDW---L 353
           W +  R   +S  M     +     EK+ F     +++  L  + ++   P+IGD    L
Sbjct: 55  WTEEPRALCSSLRMNGDQNSDVYAQEKQDFVQHFSQIVRVL-TEDEMGH-PEIGDAIARL 112

Query: 354 KKMLHYNLVGGKHTRXITTVIXYKTIEKPEKVTEHTLKMACKLGWCVEMFQAYCIVLDDI 533
           K++L YN +GGK+ R +T V+ ++ + +P K    +L+ A  +GWCVE+ QA+ +V DDI
Sbjct: 113 KEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDI 172

Query: 534 MDGSSVRRGMPCWYRRPEVGITCXFNDSLXIHSXLXEFLKTNXXDQ 671
           MD S  RRG  CWY++P VG+    ND+  + + +   LK    +Q
Sbjct: 173 MDSSLTRRGQICWYQKPGVGLDA-INDANLLEACIYRLLKLYCREQ 217


>BC010004-1|AAH10004.1|  419|Homo sapiens farnesyl diphosphate
           synthase (farnesyl pyrophosphate synthetase,
           dimethylallyl protein.
          Length = 419

 Score =  102 bits (245), Expect = 1e-21
 Identities = 55/166 (33%), Positives = 90/166 (54%), Gaps = 3/166 (1%)
 Frame = +3

Query: 183 WPQLIRYKNNSAXMTTASKNLEIINEKKMFDDLLPEVIMTLQNKSKLSEVPQIGDW---L 353
           W +  R   +S  M     +     EK+ F     +++  L  + ++   P+IGD    L
Sbjct: 54  WTEEPRALCSSLRMNGDQNSDVYAQEKQDFVQHFSQIVRVL-TEDEMGH-PEIGDAIARL 111

Query: 354 KKMLHYNLVGGKHTRXITTVIXYKTIEKPEKVTEHTLKMACKLGWCVEMFQAYCIVLDDI 533
           K++L YN +GGK+ R +T V+ ++ + +P K    +L+ A  +GWCVE+ QA+ +V DDI
Sbjct: 112 KEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDI 171

Query: 534 MDGSSVRRGMPCWYRRPEVGITCXFNDSLXIHSXLXEFLKTNXXDQ 671
           MD S  RRG  CWY++P VG+    ND+  + + +   LK    +Q
Sbjct: 172 MDSSLTRRGQICWYQKPGVGLDA-INDANLLEACIYRLLKLYCREQ 216


>AL139410-1|CAI12715.1|  419|Homo sapiens farnesyl diphosphate
           synthase (farnesyl pyrophosphate synthetase,
           dimethylallyl protein.
          Length = 419

 Score =  102 bits (245), Expect = 1e-21
 Identities = 55/166 (33%), Positives = 90/166 (54%), Gaps = 3/166 (1%)
 Frame = +3

Query: 183 WPQLIRYKNNSAXMTTASKNLEIINEKKMFDDLLPEVIMTLQNKSKLSEVPQIGDW---L 353
           W +  R   +S  M     +     EK+ F     +++  L  + ++   P+IGD    L
Sbjct: 54  WTEEPRALCSSLRMNGDQNSDVYAQEKQDFVQHFSQIVRVL-TEDEMGH-PEIGDAIARL 111

Query: 354 KKMLHYNLVGGKHTRXITTVIXYKTIEKPEKVTEHTLKMACKLGWCVEMFQAYCIVLDDI 533
           K++L YN +GGK+ R +T V+ ++ + +P K    +L+ A  +GWCVE+ QA+ +V DDI
Sbjct: 112 KEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDI 171

Query: 534 MDGSSVRRGMPCWYRRPEVGITCXFNDSLXIHSXLXEFLKTNXXDQ 671
           MD S  RRG  CWY++P VG+    ND+  + + +   LK    +Q
Sbjct: 172 MDSSLTRRGQICWYQKPGVGLDA-INDANLLEACIYRLLKLYCREQ 216


>M29863-1|AAA35820.1|  346|Homo sapiens protein ( Human farnesyl
           pyrophosphate synthetase mRNA (hpt807), 3' end. ).
          Length = 346

 Score =  102 bits (244), Expect = 2e-21
 Identities = 47/116 (40%), Positives = 72/116 (62%), Gaps = 3/116 (2%)
 Frame = +3

Query: 333 PQIGDW---LKKMLHYNLVGGKHTRXITTVIXYKTIEKPEKVTEHTLKMACKLGWCVEMF 503
           P+IGD    LK++L YN +GGK+ R +T V+ ++ + +P K    +L+ A  +GWCVE+ 
Sbjct: 29  PEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELL 88

Query: 504 QAYCIVLDDIMDGSSVRRGMPCWYRRPEVGITCXFNDSLXIHSXLXEFLKTNXXDQ 671
           QA+ +V DDIMD S  RRG  CWY++P VG+    ND+  + + +   LK    +Q
Sbjct: 89  QAFFLVADDIMDSSLTRRGQICWYQKPGVGLDA-INDANLLEACIYRLLKLYCREQ 143


>Z47055-1|CAA87327.1|  348|Homo sapiens farnesyl pyrophosphate
           synthetase like-4 protein.
          Length = 348

 Score = 97.5 bits (232), Expect = 4e-20
 Identities = 45/116 (38%), Positives = 70/116 (60%), Gaps = 3/116 (2%)
 Frame = +3

Query: 333 PQIGDW---LKKMLHYNLVGGKHTRXITTVIXYKTIEKPEKVTEHTLKMACKLGWCVEMF 503
           P+IGD    LK++L YN +GGK+ R +T  + ++ +  P K    +L+ A  +GWCVE+ 
Sbjct: 31  PEIGDAIARLKEVLEYNAIGGKYNRRLTVAVAFRELVDPRKQDADSLQRAWTVGWCVELL 90

Query: 504 QAYCIVLDDIMDGSSVRRGMPCWYRRPEVGITCXFNDSLXIHSXLXEFLKTNXXDQ 671
           QA+ +V DDIMD S  RRG  CWY++P VG+    +D+  + + +   LK    +Q
Sbjct: 91  QAFFLVADDIMDSSLTRRGQICWYQKPGVGLDA-IDDANLLEACIYPLLKLYCREQ 145


>BC050292-1|AAH50292.1|  298|Homo sapiens LOC619190 protein protein.
          Length = 298

 Score = 75.8 bits (178), Expect = 2e-13
 Identities = 36/116 (31%), Positives = 67/116 (57%), Gaps = 3/116 (2%)
 Frame = +3

Query: 333 PQIGDW---LKKMLHYNLVGGKHTRXITTVIXYKTIEKPEKVTEHTLKMACKLGWCVEMF 503
           P+ GD    LK++L YN +GGK+ R +  ++ ++ + +P K+   +L+ A  +GW  ++ 
Sbjct: 4   PETGDATARLKEVLEYNAIGGKYHRGLMVLVAFRELVEPRKLDADSLQWAPTVGWYAQLL 63

Query: 504 QAYCIVLDDIMDGSSVRRGMPCWYRRPEVGITCXFNDSLXIHSXLXEFLKTNXXDQ 671
           QA+ +V DDIMD S   +G   WY++  +G+    ND++ + + +   LK    +Q
Sbjct: 64  QAFFLVADDIMDSSLTCQGQISWYQKLGMGLDA-INDAILLEACIYCLLKLYCREQ 118


>AL139333-5|CAI15284.1| 2369|Homo sapiens dopey family member 1
           protein.
          Length = 2369

 Score = 37.9 bits (84), Expect = 0.039
 Identities = 28/82 (34%), Positives = 40/82 (48%), Gaps = 4/82 (4%)
 Frame = +3

Query: 198 RYKNNSAXMTTASKNLEIINEKKMFDDLLPEVIMTLQNKSKLSEVPQ---IGDWLKKMLH 368
           +Y+N  A +  A KN E  +E       L ++   LQN +K   VP+   IG  L + LH
Sbjct: 13  KYRNYVAAIDKALKNFEYSSEWADLISALGKLNKVLQNNAKYQVVPKKLTIGKRLAQCLH 72

Query: 369 YNLVGGKHTRXITTV-IXYKTI 431
             L GG H + + T  I +K I
Sbjct: 73  PALPGGVHRKALETYEIIFKII 94


>AL139333-4|CAM21599.1| 2465|Homo sapiens dopey family member 1
           protein.
          Length = 2465

 Score = 37.9 bits (84), Expect = 0.039
 Identities = 28/82 (34%), Positives = 40/82 (48%), Gaps = 4/82 (4%)
 Frame = +3

Query: 198 RYKNNSAXMTTASKNLEIINEKKMFDDLLPEVIMTLQNKSKLSEVPQ---IGDWLKKMLH 368
           +Y+N  A +  A KN E  +E       L ++   LQN +K   VP+   IG  L + LH
Sbjct: 13  KYRNYVAAIDKALKNFEYSSEWADLISALGKLNKVLQNNAKYQVVPKKLTIGKRLAQCLH 72

Query: 369 YNLVGGKHTRXITTV-IXYKTI 431
             L GG H + + T  I +K I
Sbjct: 73  PALPGGVHRKALETYEIIFKII 94


>AL121716-2|CAI42426.1| 2369|Homo sapiens dopey family member 1
           protein.
          Length = 2369

 Score = 37.9 bits (84), Expect = 0.039
 Identities = 28/82 (34%), Positives = 40/82 (48%), Gaps = 4/82 (4%)
 Frame = +3

Query: 198 RYKNNSAXMTTASKNLEIINEKKMFDDLLPEVIMTLQNKSKLSEVPQ---IGDWLKKMLH 368
           +Y+N  A +  A KN E  +E       L ++   LQN +K   VP+   IG  L + LH
Sbjct: 13  KYRNYVAAIDKALKNFEYSSEWADLISALGKLNKVLQNNAKYQVVPKKLTIGKRLAQCLH 72

Query: 369 YNLVGGKHTRXITTV-IXYKTI 431
             L GG H + + T  I +K I
Sbjct: 73  PALPGGVHRKALETYEIIFKII 94


>AL121716-1|CAI42425.2| 2465|Homo sapiens dopey family member 1
           protein.
          Length = 2465

 Score = 37.9 bits (84), Expect = 0.039
 Identities = 28/82 (34%), Positives = 40/82 (48%), Gaps = 4/82 (4%)
 Frame = +3

Query: 198 RYKNNSAXMTTASKNLEIINEKKMFDDLLPEVIMTLQNKSKLSEVPQ---IGDWLKKMLH 368
           +Y+N  A +  A KN E  +E       L ++   LQN +K   VP+   IG  L + LH
Sbjct: 13  KYRNYVAAIDKALKNFEYSSEWADLISALGKLNKVLQNNAKYQVVPKKLTIGKRLAQCLH 72

Query: 369 YNLVGGKHTRXITTV-IXYKTI 431
             L GG H + + T  I +K I
Sbjct: 73  PALPGGVHRKALETYEIIFKII 94


>BC063635-1|AAH63635.1|  306|Homo sapiens PDSS1 protein protein.
          Length = 306

 Score = 30.3 bits (65), Expect = 7.7
 Identities = 20/71 (28%), Positives = 29/71 (40%), Gaps = 1/71 (1%)
 Frame = +3

Query: 351 LKKMLHYNLVG-GKHTRXITTVIXYKTIEKPEKVTEHTLKMACKLGWCVEMFQAYCIVLD 527
           LK+M  Y   G GK  R I   +  +        + H       +    EM     +V D
Sbjct: 121 LKEMSEYYFDGKGKAFRPIIVALMARACNIHHNNSRHVQASQRAIALIAEMIHTASLVHD 180

Query: 528 DIMDGSSVRRG 560
           D++D +S RRG
Sbjct: 181 DVIDDASSRRG 191


>BC049211-1|AAH49211.1|  414|Homo sapiens PDSS1 protein protein.
          Length = 414

 Score = 30.3 bits (65), Expect = 7.7
 Identities = 20/71 (28%), Positives = 29/71 (40%), Gaps = 1/71 (1%)
 Frame = +3

Query: 351 LKKMLHYNLVG-GKHTRXITTVIXYKTIEKPEKVTEHTLKMACKLGWCVEMFQAYCIVLD 527
           LK+M  Y   G GK  R I   +  +        + H       +    EM     +V D
Sbjct: 120 LKEMSEYYFDGKGKAFRPIIVALMARACNIHHNNSRHVQASQRAIALIAEMIHTASLVHD 179

Query: 528 DIMDGSSVRRG 560
           D++D +S RRG
Sbjct: 180 DVIDDASSRRG 190


>AL390961-9|CAI17280.1|  415|Homo sapiens trans-prenyltransferase
           (TPT) protein.
          Length = 415

 Score = 30.3 bits (65), Expect = 7.7
 Identities = 20/71 (28%), Positives = 29/71 (40%), Gaps = 1/71 (1%)
 Frame = +3

Query: 351 LKKMLHYNLVG-GKHTRXITTVIXYKTIEKPEKVTEHTLKMACKLGWCVEMFQAYCIVLD 527
           LK+M  Y   G GK  R I   +  +        + H       +    EM     +V D
Sbjct: 121 LKEMSEYYFDGKGKAFRPIIVALMARACNIHHNNSRHVQASQRAIALIAEMIHTASLVHD 180

Query: 528 DIMDGSSVRRG 560
           D++D +S RRG
Sbjct: 181 DVIDDASSRRG 191


>AB210838-1|BAE48216.1|  415|Homo sapiens subunit 1 of decaprenyl
           diphosphate synthase protein.
          Length = 415

 Score = 30.3 bits (65), Expect = 7.7
 Identities = 20/71 (28%), Positives = 29/71 (40%), Gaps = 1/71 (1%)
 Frame = +3

Query: 351 LKKMLHYNLVG-GKHTRXITTVIXYKTIEKPEKVTEHTLKMACKLGWCVEMFQAYCIVLD 527
           LK+M  Y   G GK  R I   +  +        + H       +    EM     +V D
Sbjct: 121 LKEMSEYYFDGKGKAFRPIIVALMARACNIHHNNSRHVQASQRAIALIAEMIHTASLVHD 180

Query: 528 DIMDGSSVRRG 560
           D++D +S RRG
Sbjct: 181 DVIDDASSRRG 191


>AB209763-1|BAD93000.1|  297|Homo sapiens trans-prenyltransferase
           variant protein.
          Length = 297

 Score = 30.3 bits (65), Expect = 7.7
 Identities = 20/71 (28%), Positives = 29/71 (40%), Gaps = 1/71 (1%)
 Frame = +3

Query: 351 LKKMLHYNLVG-GKHTRXITTVIXYKTIEKPEKVTEHTLKMACKLGWCVEMFQAYCIVLD 527
           LK+M  Y   G GK  R I   +  +        + H       +    EM     +V D
Sbjct: 128 LKEMSEYYFDGKGKAFRPIIVALMARACNIHHNNSRHVQASQRAIALIAEMIHTASLVHD 187

Query: 528 DIMDGSSVRRG 560
           D++D +S RRG
Sbjct: 188 DVIDDASSRRG 198


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 105,492,509
Number of Sequences: 237096
Number of extensions: 1976778
Number of successful extensions: 7065
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 6940
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7065
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 9015132854
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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