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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= brP-0439
         (750 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

AB209851-1|BAD93088.1| 2331|Homo sapiens Basement membrane-speci...    43   0.001
X62515-1|CAA44373.1| 4393|Homo sapiens Human basement membrane h...    41   0.004
M85289-1|AAA52700.1| 4391|Homo sapiens heparan sulfate proteogly...    41   0.005
AL590556-2|CAH71870.1| 4391|Homo sapiens heparan sulfate proteog...    41   0.005
AL590103-2|CAI12125.1| 4391|Homo sapiens heparan sulfate proteog...    41   0.005
AL445795-1|CAC18534.1| 4370|Homo sapiens heparan sulfate proteog...    41   0.005
D87469-1|BAA13407.2| 2854|Homo sapiens KIAA0279 protein protein.       31   3.3  
AL390252-1|CAI13170.1| 2923|Homo sapiens cadherin, EGF LAG seven...    31   3.3  
AF234887-1|AAG00080.1| 2923|Homo sapiens FLAMINGO 1 protein.           31   3.3  
AB065955-1|BAC06168.1| 2923|Homo sapiens seven transmembrane hel...    31   3.3  
Z95636-1|CAB09137.1|  953|Homo sapiens laminin alpha 5 chain pro...    31   4.4  
BC003355-1|AAH03355.1|  670|Homo sapiens LAMA5 protein protein.        31   4.4  
AL354836-5|CAC22310.1| 3690|Homo sapiens laminin, alpha 5 protein.     31   4.4  
AK057327-1|BAB71429.1|  721|Homo sapiens protein ( Homo sapiens ...    31   4.4  
AF463518-1|AAL68839.1| 1311|Homo sapiens cell recognition protei...    31   4.4  
AF443072-1|AAM12527.1| 3695|Homo sapiens laminin alpha5 chain pr...    31   4.4  
AB100094-1|BAC55272.1| 1308|Homo sapiens hypothetical protein pr...    31   4.4  
AB051550-1|BAB21854.2| 1322|Homo sapiens KIAA1763 protein protein.     31   4.4  
AB011105-1|BAA25459.1| 1645|Homo sapiens KIAA0533 protein protein.     31   4.4  
X96395-1|CAA65259.2| 1545|Homo sapiens canalicular multidrug res...    30   7.7  
U63970-1|AAB39892.1| 1545|Homo sapiens canalicular multispecific...    30   7.7  
U49248-1|AAB09422.1| 1545|Homo sapiens canalicular multispecific...    30   7.7  
AL392107-3|CAI11010.1| 1545|Homo sapiens ATP-binding cassette, s...    30   7.7  
AL133353-7|CAI14502.1| 1545|Homo sapiens ATP-binding cassette, s...    30   7.7  
AJ132244-1|CAB45309.1| 1545|Homo sapiens multidrug resistance pr...    30   7.7  

>AB209851-1|BAD93088.1| 2331|Homo sapiens Basement membrane-specific
            heparan sulfate proteoglycan core protein precursor
            protein.
          Length = 2331

 Score = 42.7 bits (96), Expect = 0.001
 Identities = 32/97 (32%), Positives = 47/97 (48%), Gaps = 10/97 (10%)
 Frame = +2

Query: 8    HQVAARLHEDGHAWLSVDGVDK-SAPATGISNVMNADSNIYIGGIPSWLNIHG---YPGF 175
            H+V A L E     + VDG +  S  + G +  +NA  N+YIGG P    + G     G 
Sbjct: 2234 HRVTA-LREGRRGSIQVDGEELVSGRSPGPNVAVNAKGNVYIGGAPDVATLTGGRFSSGI 2292

Query: 176  IGCIENVETTDSHRG------LNLRDTAVAGRNTQLC 268
             GC++N+    +  G      L+L+  A AG NT+ C
Sbjct: 2293 TGCVKNLVLHSARPGAPPPQPLDLQHRAQAGANTRPC 2329


>X62515-1|CAA44373.1| 4393|Homo sapiens Human basement membrane
            heparan sulfate  proteoglycan core protein protein.
          Length = 4393

 Score = 41.1 bits (92), Expect = 0.004
 Identities = 32/97 (32%), Positives = 47/97 (48%), Gaps = 10/97 (10%)
 Frame = +2

Query: 8    HQVAARLHEDGHAWLSVDGVDK-SAPATGISNVMNADSNIYIGGIPSWLNIHG---YPGF 175
            H+V A L E     + VDG +  S  + G +  +NA  +IYIGG P    + G     G 
Sbjct: 4296 HRVTA-LREGRRGSIQVDGEELVSGRSPGPNVAVNAKGSIYIGGAPDVATLTGGRFSSGI 4354

Query: 176  IGCIENVETTDSHRG------LNLRDTAVAGRNTQLC 268
             GC++N+    +  G      L+L+  A AG NT+ C
Sbjct: 4355 TGCVKNLVLHSARPGAPPPQPLDLQHRAQAGANTRPC 4391


>M85289-1|AAA52700.1| 4391|Homo sapiens heparan sulfate proteoglycan
            protein.
          Length = 4391

 Score = 40.7 bits (91), Expect = 0.005
 Identities = 31/97 (31%), Positives = 47/97 (48%), Gaps = 10/97 (10%)
 Frame = +2

Query: 8    HQVAARLHEDGHAWLSVDGVDK-SAPATGISNVMNADSNIYIGGIPSWLNIHG---YPGF 175
            H+V A L E     + VDG +  S  + G +  +NA  ++YIGG P    + G     G 
Sbjct: 4294 HRVTA-LREGRRGSIQVDGEELVSGRSPGPNVAVNAKGSVYIGGAPDVATLTGGRFSSGI 4352

Query: 176  IGCIENVETTDSHRG------LNLRDTAVAGRNTQLC 268
             GC++N+    +  G      L+L+  A AG NT+ C
Sbjct: 4353 TGCVKNLVLHSARPGAPPPQPLDLQHRAQAGANTRPC 4389


>AL590556-2|CAH71870.1| 4391|Homo sapiens heparan sulfate proteoglycan
            2 protein.
          Length = 4391

 Score = 40.7 bits (91), Expect = 0.005
 Identities = 31/97 (31%), Positives = 47/97 (48%), Gaps = 10/97 (10%)
 Frame = +2

Query: 8    HQVAARLHEDGHAWLSVDGVDK-SAPATGISNVMNADSNIYIGGIPSWLNIHG---YPGF 175
            H+V A L E     + VDG +  S  + G +  +NA  ++YIGG P    + G     G 
Sbjct: 4294 HRVTA-LREGRRGSIQVDGEELVSGRSPGPNVAVNAKGSVYIGGAPDVATLTGGRFSSGI 4352

Query: 176  IGCIENVETTDSHRG------LNLRDTAVAGRNTQLC 268
             GC++N+    +  G      L+L+  A AG NT+ C
Sbjct: 4353 TGCVKNLVLHSARPGAPPPQPLDLQHRAQAGANTRPC 4389


>AL590103-2|CAI12125.1| 4391|Homo sapiens heparan sulfate proteoglycan
            2 protein.
          Length = 4391

 Score = 40.7 bits (91), Expect = 0.005
 Identities = 31/97 (31%), Positives = 47/97 (48%), Gaps = 10/97 (10%)
 Frame = +2

Query: 8    HQVAARLHEDGHAWLSVDGVDK-SAPATGISNVMNADSNIYIGGIPSWLNIHG---YPGF 175
            H+V A L E     + VDG +  S  + G +  +NA  ++YIGG P    + G     G 
Sbjct: 4294 HRVTA-LREGRRGSIQVDGEELVSGRSPGPNVAVNAKGSVYIGGAPDVATLTGGRFSSGI 4352

Query: 176  IGCIENVETTDSHRG------LNLRDTAVAGRNTQLC 268
             GC++N+    +  G      L+L+  A AG NT+ C
Sbjct: 4353 TGCVKNLVLHSARPGAPPPQPLDLQHRAQAGANTRPC 4389


>AL445795-1|CAC18534.1| 4370|Homo sapiens heparan sulfate proteoglycan
            perlecan protein.
          Length = 4370

 Score = 40.7 bits (91), Expect = 0.005
 Identities = 31/97 (31%), Positives = 47/97 (48%), Gaps = 10/97 (10%)
 Frame = +2

Query: 8    HQVAARLHEDGHAWLSVDGVDK-SAPATGISNVMNADSNIYIGGIPSWLNIHG---YPGF 175
            H+V A L E     + VDG +  S  + G +  +NA  ++YIGG P    + G     G 
Sbjct: 4273 HRVTA-LREGRRGSIQVDGEELVSGRSPGPNVAVNAKGSVYIGGAPDVATLTGGRFSSGI 4331

Query: 176  IGCIENVETTDSHRG------LNLRDTAVAGRNTQLC 268
             GC++N+    +  G      L+L+  A AG NT+ C
Sbjct: 4332 TGCVKNLVLHSARPGAPPPQPLDLQHRAQAGANTRPC 4368


>D87469-1|BAA13407.2| 2854|Homo sapiens KIAA0279 protein protein.
          Length = 2854

 Score = 31.5 bits (68), Expect = 3.3
 Identities = 23/67 (34%), Positives = 31/67 (46%), Gaps = 1/67 (1%)
 Frame = +2

Query: 38   GHAWLSVDGVDKSAPATGISNVMNAD-SNIYIGGIPSWLNIHGYPGFIGCIENVETTDSH 214
            GHA LS D   + A       +     SNI +GGIP         GF GC++ V  +D+ 
Sbjct: 1644 GHAILSFDYGQQRAEGNLGPRLHGLHLSNITVGGIPGPAGGVAR-GFRGCLQGVRVSDTP 1702

Query: 215  RGLNLRD 235
             G+N  D
Sbjct: 1703 EGVNSLD 1709


>AL390252-1|CAI13170.1| 2923|Homo sapiens cadherin, EGF LAG seven-pass
            G-type receptor 2 (flamingo homolog, Drosophila) protein.
          Length = 2923

 Score = 31.5 bits (68), Expect = 3.3
 Identities = 23/67 (34%), Positives = 31/67 (46%), Gaps = 1/67 (1%)
 Frame = +2

Query: 38   GHAWLSVDGVDKSAPATGISNVMNAD-SNIYIGGIPSWLNIHGYPGFIGCIENVETTDSH 214
            GHA LS D   + A       +     SNI +GGIP         GF GC++ V  +D+ 
Sbjct: 1713 GHAILSFDYGQQRAEGNLGPRLHGLHLSNITVGGIPGPAGGVAR-GFRGCLQGVRVSDTP 1771

Query: 215  RGLNLRD 235
             G+N  D
Sbjct: 1772 EGVNSLD 1778


>AF234887-1|AAG00080.1| 2923|Homo sapiens FLAMINGO 1 protein.
          Length = 2923

 Score = 31.5 bits (68), Expect = 3.3
 Identities = 23/67 (34%), Positives = 31/67 (46%), Gaps = 1/67 (1%)
 Frame = +2

Query: 38   GHAWLSVDGVDKSAPATGISNVMNAD-SNIYIGGIPSWLNIHGYPGFIGCIENVETTDSH 214
            GHA LS D   + A       +     SNI +GGIP         GF GC++ V  +D+ 
Sbjct: 1713 GHAILSFDYGQQRAEGNLGPRLHGLHLSNITVGGIPGPAGGVAR-GFRGCLQGVRVSDTP 1771

Query: 215  RGLNLRD 235
             G+N  D
Sbjct: 1772 EGVNSLD 1778


>AB065955-1|BAC06168.1| 2923|Homo sapiens seven transmembrane helix
            receptor protein.
          Length = 2923

 Score = 31.5 bits (68), Expect = 3.3
 Identities = 23/67 (34%), Positives = 31/67 (46%), Gaps = 1/67 (1%)
 Frame = +2

Query: 38   GHAWLSVDGVDKSAPATGISNVMNAD-SNIYIGGIPSWLNIHGYPGFIGCIENVETTDSH 214
            GHA LS D   + A       +     SNI +GGIP         GF GC++ V  +D+ 
Sbjct: 1713 GHAILSFDYGQQRAEGNLGPRLHGLHLSNITVGGIPGPAGGVAR-GFRGCLQGVRVSDTP 1771

Query: 215  RGLNLRD 235
             G+N  D
Sbjct: 1772 EGVNSLD 1778


>Z95636-1|CAB09137.1|  953|Homo sapiens laminin alpha 5 chain
           protein.
          Length = 953

 Score = 31.1 bits (67), Expect = 4.4
 Identities = 18/45 (40%), Positives = 24/45 (53%), Gaps = 4/45 (8%)
 Frame = +2

Query: 68  DKSAP-ATGISNVMNADSNIYIGGIPSWLN---IHGYPGFIGCIE 190
           D  AP A G+ N+   D   Y+GG PS      +  +PG+ GCIE
Sbjct: 115 DTVAPGAEGLLNLRPDDFVFYVGGYPSTFTPPPLLRFPGYRGCIE 159


>BC003355-1|AAH03355.1|  670|Homo sapiens LAMA5 protein protein.
          Length = 670

 Score = 31.1 bits (67), Expect = 4.4
 Identities = 18/45 (40%), Positives = 24/45 (53%), Gaps = 4/45 (8%)
 Frame = +2

Query: 68  DKSAP-ATGISNVMNADSNIYIGGIPSWLN---IHGYPGFIGCIE 190
           D  AP A G+ N+   D   Y+GG PS      +  +PG+ GCIE
Sbjct: 63  DTVAPGAEGLLNLRPDDFVFYVGGYPSTFTPPPLLRFPGYRGCIE 107


>AL354836-5|CAC22310.1| 3690|Homo sapiens laminin, alpha 5 protein.
          Length = 3690

 Score = 31.1 bits (67), Expect = 4.4
 Identities = 18/45 (40%), Positives = 24/45 (53%), Gaps = 4/45 (8%)
 Frame = +2

Query: 68   DKSAP-ATGISNVMNADSNIYIGGIPSWLN---IHGYPGFIGCIE 190
            D  AP A G+ N+   D   Y+GG PS      +  +PG+ GCIE
Sbjct: 2857 DTVAPGAEGLLNLRPDDFVFYVGGYPSTFTPPPLLRFPGYRGCIE 2901


>AK057327-1|BAB71429.1|  721|Homo sapiens protein ( Homo sapiens
           cDNA FLJ32765 fis, clone TESTI2001852, weakly similar to
           Homo sapiens contactin associated protein (Caspr) mRNA.
           ).
          Length = 721

 Score = 31.1 bits (67), Expect = 4.4
 Identities = 17/40 (42%), Positives = 22/40 (55%), Gaps = 2/40 (5%)
 Frame = +2

Query: 83  ATGISNVMNADSNIYIGGIPSWLNIHGYP--GFIGCIENV 196
           A G  N+MN D  I  GGIP+      +P   F GC+EN+
Sbjct: 272 ARGEFNLMNLDYEISFGGIPAPGKSVSFPHRNFHGCLENL 311


>AF463518-1|AAL68839.1| 1311|Homo sapiens cell recognition protein
           CASPR4 protein.
          Length = 1311

 Score = 31.1 bits (67), Expect = 4.4
 Identities = 17/40 (42%), Positives = 22/40 (55%), Gaps = 2/40 (5%)
 Frame = +2

Query: 83  ATGISNVMNADSNIYIGGIPSWLNIHGYP--GFIGCIENV 196
           A G  N+MN D  I  GGIP+      +P   F GC+EN+
Sbjct: 300 ARGEFNLMNLDYEISFGGIPAPGKSVSFPHRNFHGCLENL 339


>AF443072-1|AAM12527.1| 3695|Homo sapiens laminin alpha5 chain
            precursor protein.
          Length = 3695

 Score = 31.1 bits (67), Expect = 4.4
 Identities = 18/45 (40%), Positives = 24/45 (53%), Gaps = 4/45 (8%)
 Frame = +2

Query: 68   DKSAP-ATGISNVMNADSNIYIGGIPSWLN---IHGYPGFIGCIE 190
            D  AP A G+ N+   D   Y+GG PS      +  +PG+ GCIE
Sbjct: 2857 DTVAPGAEGLLNLRPDDFVFYVGGYPSTFTPPPLLRFPGYRGCIE 2901


>AB100094-1|BAC55272.1| 1308|Homo sapiens hypothetical protein
           protein.
          Length = 1308

 Score = 31.1 bits (67), Expect = 4.4
 Identities = 17/40 (42%), Positives = 22/40 (55%), Gaps = 2/40 (5%)
 Frame = +2

Query: 83  ATGISNVMNADSNIYIGGIPSWLNIHGYP--GFIGCIENV 196
           A G  N+MN D  I  GGIP+      +P   F GC+EN+
Sbjct: 297 ARGEFNLMNLDYEISFGGIPAPGKSVSFPHRNFHGCLENL 336


>AB051550-1|BAB21854.2| 1322|Homo sapiens KIAA1763 protein protein.
          Length = 1322

 Score = 31.1 bits (67), Expect = 4.4
 Identities = 17/40 (42%), Positives = 22/40 (55%), Gaps = 2/40 (5%)
 Frame = +2

Query: 83  ATGISNVMNADSNIYIGGIPSWLNIHGYP--GFIGCIENV 196
           A G  N+MN D  I  GGIP+      +P   F GC+EN+
Sbjct: 311 ARGEFNLMNLDYEISFGGIPAPGKSVSFPHRNFHGCLENL 350


>AB011105-1|BAA25459.1| 1645|Homo sapiens KIAA0533 protein protein.
          Length = 1645

 Score = 31.1 bits (67), Expect = 4.4
 Identities = 18/45 (40%), Positives = 24/45 (53%), Gaps = 4/45 (8%)
 Frame = +2

Query: 68  DKSAP-ATGISNVMNADSNIYIGGIPSWLN---IHGYPGFIGCIE 190
           D  AP A G+ N+   D   Y+GG PS      +  +PG+ GCIE
Sbjct: 807 DTVAPGAEGLLNLRPDDFVFYVGGYPSTFTPPPLLRFPGYRGCIE 851


>X96395-1|CAA65259.2| 1545|Homo sapiens canalicular multidrug
           resistance protein protein.
          Length = 1545

 Score = 30.3 bits (65), Expect = 7.7
 Identities = 13/36 (36%), Positives = 20/36 (55%)
 Frame = +3

Query: 264 YAETPDLSSSKRKLRNN*VKNLYAFIKLECIVYFKY 371
           +A  P      + LR   +KNL AF +L+C+V F +
Sbjct: 515 FAWEPSFRDQVQNLRKKELKNLLAFSQLQCVVIFVF 550


>U63970-1|AAB39892.1| 1545|Homo sapiens canalicular multispecific
           organic anion transporter protein.
          Length = 1545

 Score = 30.3 bits (65), Expect = 7.7
 Identities = 13/36 (36%), Positives = 20/36 (55%)
 Frame = +3

Query: 264 YAETPDLSSSKRKLRNN*VKNLYAFIKLECIVYFKY 371
           +A  P      + LR   +KNL AF +L+C+V F +
Sbjct: 515 FAWEPSFRDQVQNLRKKELKNLLAFSQLQCVVIFVF 550


>U49248-1|AAB09422.1| 1545|Homo sapiens canalicular multispecific
           organic anion transporter protein.
          Length = 1545

 Score = 30.3 bits (65), Expect = 7.7
 Identities = 13/36 (36%), Positives = 20/36 (55%)
 Frame = +3

Query: 264 YAETPDLSSSKRKLRNN*VKNLYAFIKLECIVYFKY 371
           +A  P      + LR   +KNL AF +L+C+V F +
Sbjct: 515 FAWEPSFRDQVQNLRKKELKNLLAFSQLQCVVIFVF 550


>AL392107-3|CAI11010.1| 1545|Homo sapiens ATP-binding cassette,
           sub-family C (CFTR/MRP), member 2 protein.
          Length = 1545

 Score = 30.3 bits (65), Expect = 7.7
 Identities = 13/36 (36%), Positives = 20/36 (55%)
 Frame = +3

Query: 264 YAETPDLSSSKRKLRNN*VKNLYAFIKLECIVYFKY 371
           +A  P      + LR   +KNL AF +L+C+V F +
Sbjct: 515 FAWEPSFRDQVQNLRKKELKNLLAFSQLQCVVIFVF 550


>AL133353-7|CAI14502.1| 1545|Homo sapiens ATP-binding cassette,
           sub-family C (CFTR/MRP), member 2 protein.
          Length = 1545

 Score = 30.3 bits (65), Expect = 7.7
 Identities = 13/36 (36%), Positives = 20/36 (55%)
 Frame = +3

Query: 264 YAETPDLSSSKRKLRNN*VKNLYAFIKLECIVYFKY 371
           +A  P      + LR   +KNL AF +L+C+V F +
Sbjct: 515 FAWEPSFRDQVQNLRKKELKNLLAFSQLQCVVIFVF 550


>AJ132244-1|CAB45309.1| 1545|Homo sapiens multidrug resistance
           protein 2 (MRP2) protein.
          Length = 1545

 Score = 30.3 bits (65), Expect = 7.7
 Identities = 13/36 (36%), Positives = 20/36 (55%)
 Frame = +3

Query: 264 YAETPDLSSSKRKLRNN*VKNLYAFIKLECIVYFKY 371
           +A  P      + LR   +KNL AF +L+C+V F +
Sbjct: 515 FAWEPSFRDQVQNLRKKELKNLLAFSQLQCVVIFVF 550


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 91,192,304
Number of Sequences: 237096
Number of extensions: 1708748
Number of successful extensions: 3879
Number of sequences better than 10.0: 25
Number of HSP's better than 10.0 without gapping: 3738
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3879
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 9015132854
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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