Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= brP-0433
(700 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q12882 Cluster: Dihydropyrimidine dehydrogenase [NADP+]... 280 2e-74
UniRef50_A2ELU8 Cluster: Dihydroorotate dehydrogenase family pro... 152 7e-36
UniRef50_A0CDX9 Cluster: Chromosome undetermined scaffold_17, wh... 151 2e-35
UniRef50_UPI000049A38F Cluster: dihydropyrimidine dehydrogenase;... 137 3e-31
UniRef50_Q23YG3 Cluster: Dihydroorotate dehydrogenase family pro... 125 1e-27
UniRef50_Q39PB0 Cluster: Dihydroorotate dehydrogenase 1; n=81; B... 108 1e-22
UniRef50_Q099I4 Cluster: Dihydropyrimidine dehydrogenase; n=1; S... 100 7e-20
UniRef50_P25889 Cluster: Uncharacterized protein yeiA; n=22; Bac... 90 6e-17
UniRef50_Q972L2 Cluster: 350aa long hypothetical dihydroorotate ... 86 7e-16
UniRef50_Q8PW56 Cluster: Dihydroorotate dehydrogenase; n=14; Eur... 85 1e-15
UniRef50_Q1G992 Cluster: Dihydroorotate dehydrogenase; n=3; Lact... 83 5e-15
UniRef50_A5VL42 Cluster: Dihydroorotate dehydrogenase family pro... 83 8e-15
UniRef50_A0W5K9 Cluster: Dihydroorotate dehydrogenase family pro... 81 2e-14
UniRef50_Q9V0Y6 Cluster: Dihydroorotate dehydrogenase; n=8; Eury... 79 8e-14
UniRef50_Q67PZ8 Cluster: Dihydroorotate dehydrogenase catalytic ... 79 1e-13
UniRef50_Q9LVI9 Cluster: Senescencs-related protein; dihydroorot... 79 1e-13
UniRef50_Q8G660 Cluster: Dihydroorotate dehydrogenase; n=4; Bifi... 77 3e-13
UniRef50_Q47741 Cluster: Dihydroorotate dehydrogenase B, catalyt... 77 3e-13
UniRef50_Q9K9W1 Cluster: Dihydroorotate dehydrogenase; n=1; Baci... 77 4e-13
UniRef50_Q1Q4L5 Cluster: Similar to dihydroorotate oxidase (Dihy... 74 4e-12
UniRef50_A6G037 Cluster: Dihydroorotate dehydrogenase 1; n=1; Pl... 73 5e-12
UniRef50_Q979G6 Cluster: Dihydroorotate dehydrogenase; n=4; Ther... 73 5e-12
UniRef50_Q3AC05 Cluster: Dihydroorotate dehydrogenase, catalytic... 73 9e-12
UniRef50_Q1F0W8 Cluster: Dihydroorotate dehydrogenase 1; n=1; Cl... 72 2e-11
UniRef50_A0LD69 Cluster: Dihydroorotate dehydrogenase family pro... 72 2e-11
UniRef50_A4A2Y8 Cluster: Dihydroorotate dehydrogenase; n=3; Plan... 71 2e-11
UniRef50_Q64TN0 Cluster: Dihydroorotate dehydrogenase; n=6; Bact... 71 4e-11
UniRef50_UPI00015BD53C Cluster: UPI00015BD53C related cluster; n... 70 6e-11
UniRef50_Q1MQG1 Cluster: Dihydroorotate dehydrogenase; n=2; Delt... 69 1e-10
UniRef50_A7DP74 Cluster: Dihydroorotate dehydrogenase family pro... 68 2e-10
UniRef50_Q8KC29 Cluster: Dihydroorotate dehydrogenase; n=10; Chl... 67 4e-10
UniRef50_A6L5H1 Cluster: Dihydroorotate dehydrogenase; n=1; Bact... 67 4e-10
UniRef50_Q8TXU6 Cluster: Dihydroorotate dehydrogenase; n=1; Meth... 67 4e-10
UniRef50_A5FPW7 Cluster: Dihydroorotate dehydrogenase family pro... 66 6e-10
UniRef50_A0RV22 Cluster: Dihydroorotate dehydrogenase; n=1; Cena... 66 6e-10
UniRef50_Q1IUQ6 Cluster: Dihydroorotate dehydrogenase family pro... 66 8e-10
UniRef50_Q2NEG1 Cluster: PyrD; n=1; Methanosphaera stadtmanae DS... 65 1e-09
UniRef50_A0Z3E6 Cluster: Dihydroorotate dehydrogenase/oxidoreduc... 65 2e-09
UniRef50_Q73P17 Cluster: Dihydroorotate dehydrogenase/oxidoreduc... 63 7e-09
UniRef50_A6LJ97 Cluster: Dihydroorotate dehydrogenase family pro... 62 1e-08
UniRef50_Q891J3 Cluster: Dihydroorotate dehydrogenase; n=16; Bac... 62 2e-08
UniRef50_Q9YFI6 Cluster: Dihydroorotate dehydrogenase; n=3; Desu... 62 2e-08
UniRef50_A5NSG9 Cluster: Dihydroorotate dehydrogenase family pro... 60 5e-08
UniRef50_A3DL41 Cluster: Dihydroorotate dehydrogenase family pro... 56 6e-07
UniRef50_O08358 Cluster: Dihydroorotate dehydrogenase; n=4; Sulf... 56 6e-07
UniRef50_O29513 Cluster: Dihydroorotate dehydrogenase; n=1; Arch... 53 6e-06
UniRef50_A4M861 Cluster: Dihydroorotate dehydrogenase family pro... 52 1e-05
UniRef50_A2EKA7 Cluster: Dihydroorotate dehydrogenase family pro... 52 2e-05
UniRef50_Q1AVZ1 Cluster: Dihydroorotate dehydrogenase family pro... 49 1e-04
UniRef50_A4FBL7 Cluster: Dihydroorotate dehydrogenase; n=1; Sacc... 47 4e-04
UniRef50_UPI0000F1DE0E Cluster: PREDICTED: similar to Dihydropyr... 46 7e-04
UniRef50_A6Q8G0 Cluster: Dihydroorotate dehydrogenase; n=4; Epsi... 41 0.025
UniRef50_Q7U3U2 Cluster: Dihydroorotate dehydrogenase; n=25; Cya... 38 0.18
UniRef50_Q7N0H1 Cluster: Similar to dihydroorotate dehydrogenase... 38 0.24
UniRef50_Q5PBF6 Cluster: Dihydroorotate dehydrogenase; n=12; Ric... 37 0.41
UniRef50_A6C020 Cluster: Putative uncharacterized protein; n=1; ... 37 0.55
UniRef50_A3DM44 Cluster: Dihydroorotate dehydrogenase family pro... 36 0.96
UniRef50_Q5B5Z0 Cluster: Putative uncharacterized protein; n=1; ... 35 1.7
UniRef50_Q4J443 Cluster: Dihydroorotate dehydrogenase precursor;... 34 2.9
UniRef50_Q8EYC6 Cluster: Dihydroorotate dehydrogenase; n=4; Lept... 34 3.9
UniRef50_A2U3Q1 Cluster: Manganese transporter; n=7; Bacteria|Re... 34 3.9
UniRef50_A2YPF0 Cluster: Putative uncharacterized protein; n=1; ... 34 3.9
UniRef50_A6SLQ0 Cluster: Putative uncharacterized protein; n=1; ... 34 3.9
UniRef50_Q6AE78 Cluster: Dihydroorotate dehydrogenase; n=6; Acti... 34 3.9
UniRef50_Q2JDS8 Cluster: Dihydroorotate dehydrogenase; n=3; Fran... 33 5.1
UniRef50_Q9WYG8 Cluster: Dihydroorotate dehydrogenase; n=4; Ther... 33 5.1
UniRef50_A0JYE9 Cluster: Acyltransferase 3; n=1; Arthrobacter sp... 33 6.7
UniRef50_UPI000155BFF2 Cluster: PREDICTED: hypothetical protein,... 33 8.9
UniRef50_Q9ULL8 Cluster: Protein Shroom4; n=17; Eutheria|Rep: Pr... 33 8.9
UniRef50_Q9S2C0 Cluster: Serine/threonine-protein kinase pksC; n... 33 8.9
>UniRef50_Q12882 Cluster: Dihydropyrimidine dehydrogenase [NADP+]
precursor; n=70; Eukaryota|Rep: Dihydropyrimidine
dehydrogenase [NADP+] precursor - Homo sapiens (Human)
Length = 1025
Score = 280 bits (687), Expect = 2e-74
Identities = 135/219 (61%), Positives = 164/219 (74%), Gaps = 1/219 (0%)
Frame = +1
Query: 4 GMGLACGQDPVLVKGISQWVRKAIKIPFFVKLTPNITDIVSIAVAAYEGGANGVSAINTV 183
GMGLACGQDP LV+ I +WVR+A++IPFF KLTPN+TDIVSIA AA EGGANGV+A NTV
Sbjct: 679 GMGLACGQDPELVRNICRWVRQAVQIPFFAKLTPNVTDIVSIARAAKEGGANGVTATNTV 738
Query: 184 SGLMSVKADATPWPAVGKQKRTTYGGVSGNATRPIGLRAVSAVGNKXXXXXXXXXXXXDS 363
SGLM +K+D TPWPAVG KRTTYGGVSG A RPI LRAV+++ DS
Sbjct: 739 SGLMGLKSDGTPWPAVGIAKRTTYGGVSGTAIRPIALRAVTSIARALPGFPILATGGIDS 798
Query: 364 ADSALQFILCGAPVVQICSAVQNQDFTVVEDYITGLKALLYLRS-RGLDGWTGQSPPTFK 540
A+S LQF+ GA V+Q+CSA+QNQDFTV+EDY TGLKALLYL+S L W GQSP T
Sbjct: 799 AESGLQFLHSGASVLQVCSAIQNQDFTVIEDYCTGLKALLYLKSIEELQDWDGQSPATVS 858
Query: 541 HQKGKPVQTIRDENGKVLTHFGIYNKKREQILHQNRLKL 657
HQKGKPV I + K L FG Y ++R++I+ +N+++L
Sbjct: 859 HQKGKPVPRIAELMDKKLPSFGPYLEQRKKIIAENKIRL 897
>UniRef50_A2ELU8 Cluster: Dihydroorotate dehydrogenase family protein;
n=3; Trichomonas vaginalis G3|Rep: Dihydroorotate
dehydrogenase family protein - Trichomonas vaginalis G3
Length = 811
Score = 152 bits (369), Expect = 7e-36
Identities = 78/164 (47%), Positives = 102/164 (62%)
Frame = +1
Query: 7 MGLACGQDPVLVKGISQWVRKAIKIPFFVKLTPNITDIVSIAVAAYEGGANGVSAINTVS 186
+G+A G P+ VK ISQ+V++A +PFFVKLTPNITD + IA AA EGGA+GV+ INTVS
Sbjct: 518 IGMALGTHPISVKRISQYVKEATTVPFFVKLTPNITDPIDIAQAALEGGADGVAMINTVS 577
Query: 187 GLMSVKADATPWPAVGKQKRTTYGGVSGNATRPIGLRAVSAVGNKXXXXXXXXXXXXDSA 366
G+ D TP P VGK+K GG+SG+ RPI LR +S V NK S
Sbjct: 578 GIAKFWPDGTPLPQVGKEKYVLSGGLSGDQVRPIALRQISRVHNKFPEMPILGIGGIGSG 637
Query: 367 DSALQFILCGAPVVQICSAVQNQDFTVVEDYITGLKALLYLRSR 498
+ALQ + G+ V Q+CSA+Q + +V + GL+ LY SR
Sbjct: 638 YTALQHLYAGSSVFQMCSAIQRYSYDIVREVNAGLQFYLYSWSR 681
>UniRef50_A0CDX9 Cluster: Chromosome undetermined scaffold_17, whole
genome shotgun sequence; n=1; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_17, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 997
Score = 151 bits (365), Expect = 2e-35
Identities = 95/234 (40%), Positives = 118/234 (50%), Gaps = 4/234 (1%)
Frame = +1
Query: 4 GMGLACGQDPVLVKGISQWVRKAIKIPFFVKLTPNITDIVSIAVAAYEGGANGVSAINTV 183
GMG ACG++P +VK I QWV I IP VK+TPN D IA AA EGGA V+ NT
Sbjct: 689 GMGRACGENPAIVKDICQWVTSEIDIPVIVKITPNYPDSADIAQAAKEGGAKAVTLTNTF 748
Query: 184 SGLMSVKADATPWPAVGKQKRTTYGGVSGNATRPIGLRAVSAVGNKXXXXXXXXXXXXDS 363
LM TPWPAVG++ TYGG G+ RPI LR S V
Sbjct: 749 PTLMDPDPLGTPWPAVGEENNVTYGGGCGSMLRPIALRKTSEVAKAIPDIAIFGSGGIIQ 808
Query: 364 ADSALQFILCGAPVVQICSAVQNQDF-TVVEDYITGLKALLYLR-SRGLDGWTGQSPPTF 537
D AL F+ GA QICSAVQ+QDF TV+ D T +A LY + W GQ P +
Sbjct: 809 GDHALSFLRYGASAFQICSAVQDQDFATVLYDLKTSFQAHLYASYNLNQKQWKGQFPTS- 867
Query: 538 KHQKGKPVQTIRDENG-KVLTHFGIYN-KKREQILHQNRLKLGLLDDDCVXDNR 693
QK KP N K L G+++ K ++ Q+ L + +D C+ R
Sbjct: 868 --QKQKPSFAFSSNNKLKNLVGSGLHHIKDIAEMKRQDFLVPQINEDSCLKCGR 919
>UniRef50_UPI000049A38F Cluster: dihydropyrimidine dehydrogenase; n=1;
Entamoeba histolytica HM-1:IMSS|Rep: dihydropyrimidine
dehydrogenase - Entamoeba histolytica HM-1:IMSS
Length = 1103
Score = 137 bits (331), Expect = 3e-31
Identities = 76/216 (35%), Positives = 121/216 (56%), Gaps = 16/216 (7%)
Frame = +1
Query: 7 MGLACGQDPVLVKGISQWVRKAIKIPFFVKLTPNITDIVSIAVAAYEGGANGVSAINTVS 186
M +A G P ++ +++V +++ IP + KLTPN+ +I +A AA GGA+GVS INTV
Sbjct: 595 MAMAIGVSPAAIERCTRYVVESVHIPVYPKLTPNVGNIEELAAAAMRGGASGVSTINTVF 654
Query: 187 GLMSVKADATPWPAVGKQKRTTYGGVSGNATRPIGLRAVSAV--GNKXXXXXXXXXXXXD 360
G+ + PWP VG ++ T GG+SG+ RPI +R ++ V N+
Sbjct: 655 GISEITLSGHPWPQVGVERNTISGGLSGDLVRPIAIRQIAQVLRHNENVRGHLLGIGGVR 714
Query: 361 SADSALQFILCGAPVVQICSAVQNQDFTVVEDYITGLKALL----------YLRSRGLDG 510
SA++A+Q I GA VVQ+CS+VQ + +V++ I+G K +L YL S+G++
Sbjct: 715 SAETAMQLIYTGASVVQMCSSVQKWSYDIVDEIISGTKFILYCWSRPDLRGYLNSQGVES 774
Query: 511 WT--GQSPP--TFKHQKGKPVQTIRDENGKVLTHFG 606
+ G+ P T +++ KPV + + G L H G
Sbjct: 775 FMPYGEKTPFWTLDNKQDKPVPKLAEVTGIALKHIG 810
>UniRef50_Q23YG3 Cluster: Dihydroorotate dehydrogenase family protein;
n=1; Tetrahymena thermophila SB210|Rep: Dihydroorotate
dehydrogenase family protein - Tetrahymena thermophila
SB210
Length = 1080
Score = 125 bits (301), Expect = 1e-27
Identities = 71/180 (39%), Positives = 92/180 (51%), Gaps = 4/180 (2%)
Frame = +1
Query: 4 GMGLACGQDPVLVKGISQWVRKAIKIPFFVKLTPNITDIVSIAVAAYEGGANGVSAINTV 183
GMG ACG+DP +V+ I+ WV KIP VK+TPN +A AAYEGGA V+ NT+
Sbjct: 764 GMGRACGEDPDIVRDITSWVTSQTKIPIIVKITPNYGQAEILAKAAYEGGAKAVTLTNTM 823
Query: 184 SGLMSVKADATPWPAVGKQKRTTYGGVSGNATRPIGLRAVSAVGNKXXXXXXXXXXXXDS 363
GL+ D + VG +K GG +G+ RP +R V S
Sbjct: 824 PGLVDPYPDGESFNGVGVEKNVAPGGSTGSILRPFAMRKCVDVAKFVPEIDIFASGGIIS 883
Query: 364 ADSALQFILCGAPVVQICSAVQNQD-FTVVEDYITGLKALLYLRSR---GLDGWTGQSPP 531
D + ++ GA +QICSAVQN D TV D T L+A +Y S +GW GQ PP
Sbjct: 884 GDHGINYLHYGAKALQICSAVQNLDAATVFYDLKTSLQANMYANSSQKLKKNGWKGQYPP 943
>UniRef50_Q39PB0 Cluster: Dihydroorotate dehydrogenase 1; n=81;
Bacteria|Rep: Dihydroorotate dehydrogenase 1 -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 438
Score = 108 bits (260), Expect = 1e-22
Identities = 61/159 (38%), Positives = 90/159 (56%), Gaps = 3/159 (1%)
Frame = +1
Query: 4 GMGLACGQDPVLVKGISQWVRKAIKIPFFVKLTPNITDIVSIAVAAYEGGANGVSAINTV 183
GMG A GQ P V+ +++WV++ K+P VKLTPNI+DI + AAY+GGA+GVS INT+
Sbjct: 145 GMGAAVGQVPEYVEMVTRWVKEGTKLPCLVKLTPNISDIRMGSRAAYKGGADGVSLINTI 204
Query: 184 SGLMSVKAD-ATPWPAVGKQKRTTYGGVSGNATRPIGLRAVSAVGN--KXXXXXXXXXXX 354
+ +++V D P P V + T+GG G A +PI L V+ + +
Sbjct: 205 NSIVAVDLDHMAPMPMV--DGKGTHGGYCGPAVKPIALNMVAEIARDPETPNLPISGIGG 262
Query: 355 XDSADSALQFILCGAPVVQICSAVQNQDFTVVEDYITGL 471
S A +F++ GA VQ+C+A + F +V D GL
Sbjct: 263 ISSWRDAAEFMVLGAGSVQVCTAAMHYGFRIVSDLADGL 301
>UniRef50_Q099I4 Cluster: Dihydropyrimidine dehydrogenase; n=1;
Stigmatella aurantiaca DW4/3-1|Rep: Dihydropyrimidine
dehydrogenase - Stigmatella aurantiaca DW4/3-1
Length = 462
Score = 99.5 bits (237), Expect = 7e-20
Identities = 62/185 (33%), Positives = 93/185 (50%), Gaps = 6/185 (3%)
Frame = +1
Query: 4 GMGLACGQDPVLVKGISQWVRKAIKIPFFVKLTPNITDIVSIAVAAYEGGANGVSAINTV 183
GMG A G +P +++ I++W + ++P VKLTPN+ DI+ AA G +S INTV
Sbjct: 142 GMGSAVGAEPKVLEEIARWAVEFARVPVIVKLTPNVGDILEPGEAAVRAGVPALSLINTV 201
Query: 184 SGLMSVKAD-ATPWPAVGKQKRTTYGGVSGNATRPIGLRAVSAVGNKXXXXXXXXXXXXD 360
+M V D P P VG +T GG G A +PI L +S +
Sbjct: 202 KSIMGVDLDRMVPLPRVG--DASTNGGYCGPAVKPIALHLLSQLARHPQCGRLAISGIGG 259
Query: 361 SAD--SALQFILCGAPVVQICSAVQNQDFTVVEDYITGLKALLYLRSRGLDG---WTGQS 525
++ A +FI GA VQ+C+AV + F +VED + GL +L +G+ G++
Sbjct: 260 ISNWRDAAEFIALGATSVQVCTAVMHHGFRIVEDMLEGLSD--FLDEKGMSSVAELRGRA 317
Query: 526 PPTFK 540
P F+
Sbjct: 318 VPAFR 322
>UniRef50_P25889 Cluster: Uncharacterized protein yeiA; n=22;
Bacteria|Rep: Uncharacterized protein yeiA - Escherichia
coli (strain K12)
Length = 411
Score = 89.8 bits (213), Expect = 6e-17
Identities = 51/169 (30%), Positives = 87/169 (51%), Gaps = 2/169 (1%)
Frame = +1
Query: 7 MGLACGQDPVLVKGISQWVRKAIKIPFFVKLTPNITDIVSIAVAAYEGGANGVSAINTVS 186
MG GQ P LV+ + V++ +P K+TPNI D+ +A+AA GGA+G++AINTV
Sbjct: 145 MGSDVGQSPELVEKYCRAVKRGSTLPMLAKMTPNIGDMCEVALAAKRGGADGIAAINTVK 204
Query: 187 GLMSVKADATPWPAVGKQKRTTYGGVSGNATRPIGLRAVSAVGN--KXXXXXXXXXXXXD 360
+ ++ + + K ++ G SG A +PI LR + + + +
Sbjct: 205 SITNIDLNQKIGMPIVNGK-SSISGYSGKAVKPIALRFIQQMRTHPELRDFPISGIGGIE 263
Query: 361 SADSALQFILCGAPVVQICSAVQNQDFTVVEDYITGLKALLYLRSRGLD 507
+ + A +F+L GA +Q+ + + + +VED +GL YL +G D
Sbjct: 264 TWEDAAEFLLLGAATLQVTTGIMQYGYRIVEDMASGLSH--YLADQGFD 310
>UniRef50_Q972L2 Cluster: 350aa long hypothetical dihydroorotate
dehydrogenase; n=1; Sulfolobus tokodaii|Rep: 350aa long
hypothetical dihydroorotate dehydrogenase - Sulfolobus
tokodaii
Length = 350
Score = 86.2 bits (204), Expect = 7e-16
Identities = 56/159 (35%), Positives = 84/159 (52%), Gaps = 1/159 (0%)
Frame = +1
Query: 10 GLACGQDPVLVKGISQWVRKAIKIPFFVKLTPNITDIVSIAVAAYEGGANGVSAINTVSG 189
G GQ LV+ ++ V ++ IP KLTPNITDI A AA GA V+AINTV+G
Sbjct: 147 GAFIGQHADLVQEYTKEVVSSVGIPVIAKLTPNITDIRETAKAAENAGAKAVTAINTVNG 206
Query: 190 LMSVKAD-ATPWPAVGKQKRTTYGGVSGNATRPIGLRAVSAVGNKXXXXXXXXXXXXDSA 366
+++V + A P P + + YGG+SG A +PIGL AVS + D
Sbjct: 207 VIAVDIERAQPLPDINGY--SGYGGISGPAVKPIGLAAVSKIYTSTSLQISGVGGIFDWR 264
Query: 367 DSALQFILCGAPVVQICSAVQNQDFTVVEDYITGLKALL 483
D A+++I+ GA VQ + + F + ++ L++ +
Sbjct: 265 D-AVEYIMMGATTVQSVTYTILKGFEFINEWKKELESFM 302
>UniRef50_Q8PW56 Cluster: Dihydroorotate dehydrogenase; n=14;
Euryarchaeota|Rep: Dihydroorotate dehydrogenase -
Methanosarcina mazei (Methanosarcina frisia)
Length = 314
Score = 85.4 bits (202), Expect = 1e-15
Identities = 53/160 (33%), Positives = 87/160 (54%)
Frame = +1
Query: 4 GMGLACGQDPVLVKGISQWVRKAIKIPFFVKLTPNITDIVSIAVAAYEGGANGVSAINTV 183
G G A G +P LV+ ++ V+ + +P +VKLTPN+ DI I AA GGA+ V AINTV
Sbjct: 144 GYGAAIGSNPCLVEAVTAAVKDVVNVPVWVKLTPNVADITCIGNAAESGGADAVVAINTV 203
Query: 184 SGLMSVKADATPWPAVGKQKRTTYGGVSGNATRPIGLRAVSAVGNKXXXXXXXXXXXXDS 363
G M++ + + +P +G + GG+SG A +P+ ++ V + S
Sbjct: 204 KG-MAIDIE-SGYPVLGNRS----GGLSGKAVKPVAVKCVYDLFT-ALEIPVIGVGGVSS 256
Query: 364 ADSALQFILCGAPVVQICSAVQNQDFTVVEDYITGLKALL 483
+ A++ I+ GA VQ+ SAV ++ + + G++A L
Sbjct: 257 WEDAVEMIMAGAAAVQVGSAVYDR-VGIFSEIGKGIEAFL 295
>UniRef50_Q1G992 Cluster: Dihydroorotate dehydrogenase; n=3;
Lactobacillus delbrueckii|Rep: Dihydroorotate
dehydrogenase - Lactobacillus delbrueckii subsp.
bulgaricus (strain ATCC 11842 / DSM20081)
Length = 309
Score = 83.4 bits (197), Expect = 5e-15
Identities = 55/159 (34%), Positives = 88/159 (55%), Gaps = 1/159 (0%)
Frame = +1
Query: 10 GLACGQDPVLVKGISQWVRKAIKIPFFVKLTPNITDIVSIAVAAYEGGANGVSAINTVSG 189
G+ G P +++ I++ V++ + +P +VKLTPN+T IV IA AA GGA+G++ INT
Sbjct: 140 GMTFGIVPEMLEKITRLVKEKVDLPVYVKLTPNVTSIVEIAQAAEGGGADGLTLINT--- 196
Query: 190 LMSVKAD-ATPWPAVGKQKRTTYGGVSGNATRPIGLRAVSAVGNKXXXXXXXXXXXXDSA 366
L+ + D T P +G +GG+ G A +P+ +R V+ V + +S
Sbjct: 197 LLVLHLDLKTRRPVLGND----FGGLYGQAVKPVAVRMVAQV-KQATSLPIIGVGGINSP 251
Query: 367 DSALQFILCGAPVVQICSAVQNQDFTVVEDYITGLKALL 483
+ A +FIL GA VQI ++ D ++ I GL A+L
Sbjct: 252 EDAAEFILAGASAVQI-GSMSFYDKLAIKHVIDGLPAVL 289
>UniRef50_A5VL42 Cluster: Dihydroorotate dehydrogenase family
protein; n=2; Lactobacillus reuteri|Rep: Dihydroorotate
dehydrogenase family protein - Lactobacillus reuteri
F275
Length = 432
Score = 82.6 bits (195), Expect = 8e-15
Identities = 50/170 (29%), Positives = 86/170 (50%), Gaps = 3/170 (1%)
Frame = +1
Query: 7 MGLACGQDPVLVKGISQWVRKAIKIPFFVKLTPNITDIVSIAVAAYEGGANGVSAINTVS 186
MG G +P L K + V++ +P K+TPNIT +V + A EGGA+G SAINTV
Sbjct: 147 MGSDVGTNPELCKKNCEAVKRGTSLPVLAKMTPNITTMVPVVKACLEGGADGFSAINTVK 206
Query: 187 GLMSVK-ADATPWPAVGKQKRTTYGGVSGNATRPIGLRAVSAVGNK--XXXXXXXXXXXX 357
++ V P + +++ G+SG A +PI LR + + +
Sbjct: 207 SIVDVDLKKKVGLPNI--DGKSSVSGLSGKAVKPIALRFLQQLRSAAGLEQLPISGIGGI 264
Query: 358 DSADSALQFILCGAPVVQICSAVQNQDFTVVEDYITGLKALLYLRSRGLD 507
++ + A +FIL GA +Q+ +A+ + +++D GL + Y+ + +D
Sbjct: 265 ETWEDAAEFILLGATTLQVTTAIMEYGYRIIDDLTNGL--MHYMEEQHVD 312
>UniRef50_A0W5K9 Cluster: Dihydroorotate dehydrogenase family
protein; n=1; Geobacter lovleyi SZ|Rep: Dihydroorotate
dehydrogenase family protein - Geobacter lovleyi SZ
Length = 398
Score = 81.4 bits (192), Expect = 2e-14
Identities = 54/153 (35%), Positives = 76/153 (49%), Gaps = 3/153 (1%)
Frame = +1
Query: 4 GMGLACGQDPVLVKGISQWVR--KAIKIPFFVKLTPNITDIVSIAVAAYEGGANGVSAIN 177
G G A GQ+P I++WV K I IP KLT + +I +IA GA+G AIN
Sbjct: 145 GRGAAIGQNPDYAAQITRWVTDCKEITIPVIPKLTAAVANIQNIAEELALAGAHGFCAIN 204
Query: 178 TVSGLMSVK-ADATPWPAVGKQKRTTYGGVSGNATRPIGLRAVSAVGNKXXXXXXXXXXX 354
T+ P P +G +T+YGG SG +PI LRAVS +
Sbjct: 205 TIPSFFGFDLRTLRPKPDIG--GKTSYGGYSGPGIKPIALRAVSELCQSPGLPVMASGGI 262
Query: 355 XDSADSALQFILCGAPVVQICSAVQNQDFTVVE 453
+ D A++F+L GAPVVQ+ + V F +++
Sbjct: 263 ANGFD-AVEFMLLGAPVVQMATEVMLHGFGIID 294
>UniRef50_Q9V0Y6 Cluster: Dihydroorotate dehydrogenase; n=8;
Euryarchaeota|Rep: Dihydroorotate dehydrogenase -
Pyrococcus abyssi
Length = 303
Score = 79.4 bits (187), Expect = 8e-14
Identities = 57/166 (34%), Positives = 81/166 (48%)
Frame = +1
Query: 4 GMGLACGQDPVLVKGISQWVRKAIKIPFFVKLTPNITDIVSIAVAAYEGGANGVSAINTV 183
G G+ GQ P V + + V+ P KLTPN++DI + +AA + GA+GVSAINT
Sbjct: 133 GYGMEIGQKPENVYEVVKAVKDVTDKPVIAKLTPNVSDIRELGLAAEKAGADGVSAINT- 191
Query: 184 SGLMSVKADATPWPAVGKQKRTTYGGVSGNATRPIGLRAVSAVGNKXXXXXXXXXXXXDS 363
VKA A A +GG SG +PI LRAV + +
Sbjct: 192 -----VKAIAIDIYAKRPILSNKFGGYSGPGVKPIALRAVYDLASSLDIPVIGIGGITTW 246
Query: 364 ADSALQFILCGAPVVQICSAVQNQDFTVVEDYITGLKALLYLRSRG 501
D A++F+L GA +QI +AV + F+V + G+ YL+ G
Sbjct: 247 QD-AVEFLLAGASALQIGTAVYLRGFSVFREIAEGISR--YLKEEG 289
>UniRef50_Q67PZ8 Cluster: Dihydroorotate dehydrogenase catalytic
subunit; n=6; Bacteria|Rep: Dihydroorotate dehydrogenase
catalytic subunit - Symbiobacterium thermophilum
Length = 306
Score = 78.6 bits (185), Expect = 1e-13
Identities = 49/138 (35%), Positives = 73/138 (52%)
Frame = +1
Query: 10 GLACGQDPVLVKGISQWVRKAIKIPFFVKLTPNITDIVSIAVAAYEGGANGVSAINTVSG 189
G+A G P ++ VRKA +P VKL+PN+ D+V+IA A + GA+G+S INT+ G
Sbjct: 140 GMAFGTTPGSAAAVTAAVRKATTLPLIVKLSPNVADVVAIARAVEDAGADGLSVINTLQG 199
Query: 190 LMSVKADATPWPAVGKQKRTTYGGVSGNATRPIGLRAVSAVGNKXXXXXXXXXXXXDSAD 369
MS+ P +G +GG+SG A +P+ LR V V D
Sbjct: 200 -MSIDI-RRGRPHLG----NVFGGLSGPAIKPVALRMVWQVAGAVKVPVIGVGGIMSGED 253
Query: 370 SALQFILCGAPVVQICSA 423
+A +F++ GA VQ+ +A
Sbjct: 254 AA-EFLMAGASAVQVGTA 270
>UniRef50_Q9LVI9 Cluster: Senescencs-related protein; dihydroorotate
dehydrogenase-like protein; n=12; cellular
organisms|Rep: Senescencs-related protein;
dihydroorotate dehydrogenase-like protein - Arabidopsis
thaliana (Mouse-ear cress)
Length = 426
Score = 78.6 bits (185), Expect = 1e-13
Identities = 50/162 (30%), Positives = 74/162 (45%), Gaps = 6/162 (3%)
Frame = +1
Query: 7 MGLACGQDPVLVKGISQWVRKAIKIPFFVKLTPNITDIVSIAVAAYEGGANGVSAINTVS 186
MG A GQD L+ + W+ +P + K+TPNITDI A + + G G++AINT+
Sbjct: 200 MGAAVGQDCALLDEVCGWINAKATVPVWAKMTPNITDITEPARVSLKSGCEGIAAINTIM 259
Query: 187 GLMSVKADA-TPWPAVGKQKRTTYGGVSGNATRPIGLRAVSAVGNK-----XXXXXXXXX 348
+M + P P V + +T GG S A RPI L V +
Sbjct: 260 SVMGIDMKTLRPEPCV--EGYSTPGGYSYKAVRPIALAKVMNIAKMMKSEFSEDRSLSGI 317
Query: 349 XXXDSADSALQFILCGAPVVQICSAVQNQDFTVVEDYITGLK 474
++ A +FIL G+ VQ+C+ V + V+ LK
Sbjct: 318 GGVETGYDAAEFILLGSNTVQVCTGVMMHGYGHVKTLCAELK 359
>UniRef50_Q8G660 Cluster: Dihydroorotate dehydrogenase; n=4;
Bifidobacterium|Rep: Dihydroorotate dehydrogenase -
Bifidobacterium longum
Length = 323
Score = 77.4 bits (182), Expect = 3e-13
Identities = 50/138 (36%), Positives = 69/138 (50%)
Frame = +1
Query: 10 GLACGQDPVLVKGISQWVRKAIKIPFFVKLTPNITDIVSIAVAAYEGGANGVSAINTVSG 189
G++ G DPV + + +R P VKLTPN+TDI A AA E GA+ +S INT+ G
Sbjct: 156 GMSVGTDPVALANLMDRLRPMTDKPMIVKLTPNVTDITVPARAAVEHGADALSMINTLKG 215
Query: 190 LMSVKADATPWPAVGKQKRTTYGGVSGNATRPIGLRAVSAVGNKXXXXXXXXXXXXDSAD 369
M + T P + GGVSG A P+GL AV V DS +
Sbjct: 216 -MRINI-RTGKPIIA----NVTGGVSGPAVLPVGLAAVYRVRTALPEIPIIGLGGIDSGE 269
Query: 370 SALQFILCGAPVVQICSA 423
AL+++ GA V++ +A
Sbjct: 270 KALEYLYAGANAVEVGAA 287
>UniRef50_Q47741 Cluster: Dihydroorotate dehydrogenase B, catalytic
subunit; n=104; Bacteria|Rep: Dihydroorotate
dehydrogenase B, catalytic subunit - Enterococcus
faecalis (Streptococcus faecalis)
Length = 312
Score = 77.4 bits (182), Expect = 3e-13
Identities = 48/139 (34%), Positives = 74/139 (53%), Gaps = 1/139 (0%)
Frame = +1
Query: 10 GLACGQDPVLVKGISQWVRKAIKIPFFVKLTPNITDIVSIAVAAYEGGANGVSAINTVSG 189
G+A G DP + ++Q V+K +P +VKL+PN+TDIV IA A GGA+G S INT+ G
Sbjct: 140 GIAFGTDPEVAFQLTQAVKKVASVPIYVKLSPNVTDIVPIAQAIEAGGADGFSMINTLLG 199
Query: 190 L-MSVKADATPWPAVGKQKRTTYGGVSGNATRPIGLRAVSAVGNKXXXXXXXXXXXXDSA 366
+ + +K T P + Q GG+SG A +P+ +R + V + +
Sbjct: 200 MRIDLK---TRKPILANQT----GGLSGPAIKPVAIRLIRQVAS-VSQLPIIGMGGVQTV 251
Query: 367 DSALQFILCGAPVVQICSA 423
D L+ + GA V + +A
Sbjct: 252 DDVLEMFMAGASAVGVGTA 270
>UniRef50_Q9K9W1 Cluster: Dihydroorotate dehydrogenase; n=1;
Bacillus halodurans|Rep: Dihydroorotate dehydrogenase -
Bacillus halodurans
Length = 305
Score = 77.0 bits (181), Expect = 4e-13
Identities = 47/138 (34%), Positives = 74/138 (53%)
Frame = +1
Query: 10 GLACGQDPVLVKGISQWVRKAIKIPFFVKLTPNITDIVSIAVAAYEGGANGVSAINTVSG 189
G+A G P + ++Q V++ +P +VKL+PN++DIV +A A GA+G+S INT+ G
Sbjct: 137 GIAFGTVPDVAAQLTQEVKRVSTVPVYVKLSPNVSDIVEMAQAVERAGADGLSMINTLLG 196
Query: 190 LMSVKADATPWPAVGKQKRTTYGGVSGNATRPIGLRAVSAVGNKXXXXXXXXXXXXDSAD 369
+ TP A G GG+SG A +P+ +R + V ++ SAD
Sbjct: 197 MRLDLKRRTPILANGT------GGLSGPAIKPVAIRMIYQV-SQAVSIPIIGMGGIQSAD 249
Query: 370 SALQFILCGAPVVQICSA 423
L+F+L GA V + +A
Sbjct: 250 DVLEFMLAGADAVAVGTA 267
>UniRef50_Q1Q4L5 Cluster: Similar to dihydroorotate oxidase
(Dihydroorotate dehydrogenase B) catalytic subunit; n=1;
Candidatus Kuenenia stuttgartiensis|Rep: Similar to
dihydroorotate oxidase (Dihydroorotate dehydrogenase B)
catalytic subunit - Candidatus Kuenenia stuttgartiensis
Length = 306
Score = 73.7 bits (173), Expect = 4e-12
Identities = 49/158 (31%), Positives = 79/158 (50%), Gaps = 1/158 (0%)
Frame = +1
Query: 4 GMGLACGQD-PVLVKGISQWVRKAIKIPFFVKLTPNITDIVSIAVAAYEGGANGVSAINT 180
G GL GQ P I+ VR+ +P FVK++PN+ +I SIA AA + GANG++A+N+
Sbjct: 135 GFGLLSGQGTPKATYEITYAVRRKTNVPIFVKISPNVPEITSIAKAAEDAGANGITAVNS 194
Query: 181 VSGLMSVKADATPWPAVGKQKRTTYGGVSGNATRPIGLRAVSAVGNKXXXXXXXXXXXXD 360
+ M + ++ P +G + GGV+G+A RPI +R V V +
Sbjct: 195 MGPGMVINIESKK-PVLGFK----VGGVTGDALRPIAVRCVYDV-YQAVKIPIIGVGGIS 248
Query: 361 SADSALQFILCGAPVVQICSAVQNQDFTVVEDYITGLK 474
+ A++ ++ GA V I + V + V +K
Sbjct: 249 TGRHAIEMMMAGASAVGIGTGVYTRGINVFSKVCAEMK 286
>UniRef50_A6G037 Cluster: Dihydroorotate dehydrogenase 1; n=1;
Plesiocystis pacifica SIR-1|Rep: Dihydroorotate
dehydrogenase 1 - Plesiocystis pacifica SIR-1
Length = 334
Score = 73.3 bits (172), Expect = 5e-12
Identities = 44/135 (32%), Positives = 70/135 (51%)
Frame = +1
Query: 10 GLACGQDPVLVKGISQWVRKAIKIPFFVKLTPNITDIVSIAVAAYEGGANGVSAINTVSG 189
G+ G P + +++ +A ++P VKLTPN++DIV++A A E GA GVS INT++
Sbjct: 153 GIEFGTVPEVAHRLTKACVEASEVPIVVKLTPNVSDIVAMAQAVKEAGAIGVSLINTITA 212
Query: 190 LMSVKADATPWPAVGKQKRTTYGGVSGNATRPIGLRAVSAVGNKXXXXXXXXXXXXDSAD 369
+ A + + TTYGG+SG A +P+ LR V V + +
Sbjct: 213 M------AIDVRSRRSRIATTYGGLSGPAIKPVALRMVHQVAKALPGFPICGMGGILTGE 266
Query: 370 SALQFILCGAPVVQI 414
L++ + GA VQ+
Sbjct: 267 DVLEYFIAGAHCVQL 281
>UniRef50_Q979G6 Cluster: Dihydroorotate dehydrogenase; n=4;
Thermoplasmatales|Rep: Dihydroorotate dehydrogenase -
Thermoplasma volcanium
Length = 301
Score = 73.3 bits (172), Expect = 5e-12
Identities = 49/141 (34%), Positives = 73/141 (51%)
Frame = +1
Query: 4 GMGLACGQDPVLVKGISQWVRKAIKIPFFVKLTPNITDIVSIAVAAYEGGANGVSAINTV 183
G GL G DP LV+ I ++ +K+P F KL+PN+++I+ IA AA + A+ INT
Sbjct: 133 GFGLEVGSDPDLVEDIVNEIKSKVKVPVFAKLSPNVSNIIEIAKAAEK--ADAYVLINT- 189
Query: 184 SGLMSVKADATPWPAVGKQKRTTYGGVSGNATRPIGLRAVSAVGNKXXXXXXXXXXXXDS 363
VKA A + YGG+SG A +P+G+R V V K +
Sbjct: 190 -----VKAMAIDIYSRSPVLSNLYGGLSGPAIKPVGIRYVYEV-KKETGKEIIGVGGISN 243
Query: 364 ADSALQFILCGAPVVQICSAV 426
A+++I+ GA VQI +A+
Sbjct: 244 YKDAIEYIMAGASAVQIGTAL 264
>UniRef50_Q3AC05 Cluster: Dihydroorotate dehydrogenase, catalytic
subunit; n=1; Carboxydothermus hydrogenoformans
Z-2901|Rep: Dihydroorotate dehydrogenase, catalytic
subunit - Carboxydothermus hydrogenoformans (strain
Z-2901 / DSM 6008)
Length = 307
Score = 72.5 bits (170), Expect = 9e-12
Identities = 51/138 (36%), Positives = 72/138 (52%), Gaps = 1/138 (0%)
Frame = +1
Query: 10 GLACGQDPVLVKGISQWVRKAIKIPFFVKLTPNITDIVSIAVAAYEGGANGVSAINTVSG 189
G+A G D +K I VRK VKLTPN+TDI A AA GA+ ++ INT +G
Sbjct: 136 GIAFGTDLEALKQIVSSVRKIYSKTLIVKLTPNVTDITVYAKAAENAGADALTLINTFTG 195
Query: 190 L-MSVKADATPWPAVGKQKRTTYGGVSGNATRPIGLRAVSAVGNKXXXXXXXXXXXXDSA 366
+ + VK+ P +G + +GGVSG A RP+ ++ V K DS
Sbjct: 196 MVIDVKSKK---PILGNK----HGGVSGPAIRPMAVKMVYDC-FKAVSIPIIGVGGIDSK 247
Query: 367 DSALQFILCGAPVVQICS 420
++AL+F L GA +Q+ S
Sbjct: 248 EAALEFFLAGATAIQVGS 265
>UniRef50_Q1F0W8 Cluster: Dihydroorotate dehydrogenase 1; n=1;
Clostridium oremlandii OhILAs|Rep: Dihydroorotate
dehydrogenase 1 - Clostridium oremlandii OhILAs
Length = 372
Score = 71.7 bits (168), Expect = 2e-11
Identities = 45/157 (28%), Positives = 79/157 (50%), Gaps = 1/157 (0%)
Frame = +1
Query: 73 IKIPFFVKLTPNITDIVSIAVAAYEGGANGVSAINTVSGLMSVKADATPWPAVGKQKRTT 252
IKIP VKL+ N ++V +A AA + GA+ +S I+TV + V + G+ T
Sbjct: 153 IKIPVMVKLSSNTVNVVKLARAAEKAGASAISGIDTVRSIAGVDIEK------GRVLLPT 206
Query: 253 YGGVSGNATRPIGLRAVSAVGNKXXXXXXXXXXXXDSADSALQFILCGAPVVQICSAVQN 432
+GG SG+A RPIGL A++++ + + + L++++ GA VQ+C+++
Sbjct: 207 FGGYSGDAIRPIGLAAIASIA-QATSIPICGIGGITNYEHILEYMMLGASTVQVCTSIIL 265
Query: 433 QDFTVVEDYITGLKALLYLRS-RGLDGWTGQSPPTFK 540
+ + + GL + S R D G + + K
Sbjct: 266 NGYEHISTLLDGLNGWMAQHSYRNFDEIKGMALVSLK 302
>UniRef50_A0LD69 Cluster: Dihydroorotate dehydrogenase family
protein; n=7; Proteobacteria|Rep: Dihydroorotate
dehydrogenase family protein - Magnetococcus sp. (strain
MC-1)
Length = 312
Score = 71.7 bits (168), Expect = 2e-11
Identities = 45/141 (31%), Positives = 71/141 (50%), Gaps = 2/141 (1%)
Frame = +1
Query: 10 GLACGQDPVLVKGISQWVRKAIKIPFFVKLTPNITDIVSIAVAAYEGGANGVSAINTVSG 189
G+A G DP + + + VR+A P KL+PN+TDI ++A A E G++ +S INT+ G
Sbjct: 142 GIAFGSDPDMAAAVVEEVRRATTKPIITKLSPNVTDITTVAKRAIEAGSDALSVINTLMG 201
Query: 190 LMSVKADATPWPAVGKQKRTTYGGVSGNATRPIGLRAVSAVGN--KXXXXXXXXXXXXDS 363
M++ P +G + GG+SG A +P+ L V + S
Sbjct: 202 -MAIDLKKRR-PVLGNLQ----GGLSGPAVKPVALLKVWQTYQLARQHQIPIIGQGGIAS 255
Query: 364 ADSALQFILCGAPVVQICSAV 426
AD L+F L GA +C+++
Sbjct: 256 ADDVLEFFLVGASATGLCTSL 276
>UniRef50_A4A2Y8 Cluster: Dihydroorotate dehydrogenase; n=3;
Planctomycetaceae|Rep: Dihydroorotate dehydrogenase -
Blastopirellula marina DSM 3645
Length = 317
Score = 71.3 bits (167), Expect = 2e-11
Identities = 45/138 (32%), Positives = 65/138 (47%)
Frame = +1
Query: 10 GLACGQDPVLVKGISQWVRKAIKIPFFVKLTPNITDIVSIAVAAYEGGANGVSAINTVSG 189
G+ G P + + VR P KLTPN+ I +A AA EGGA+G+SAINT+ G
Sbjct: 137 GVDFGICPETCRDLIASVRAQCTKPLLAKLTPNVARIADVAAAAEEGGADGISAINTLLG 196
Query: 190 LMSVKADATPWPAVGKQKRTTYGGVSGNATRPIGLRAVSAVGNKXXXXXXXXXXXXDSAD 369
+ A W GG+SG A +P+ LR V + + + D
Sbjct: 197 M------AVDWRRQKPLLGNVMGGLSGPAIKPVALRCVYQIAQR-VKIPVIGIGGIGTID 249
Query: 370 SALQFILCGAPVVQICSA 423
++F++ GA VQI +A
Sbjct: 250 DVMEFLVAGATAVQIGTA 267
>UniRef50_Q64TN0 Cluster: Dihydroorotate dehydrogenase; n=6;
Bacteroides|Rep: Dihydroorotate dehydrogenase -
Bacteroides fragilis
Length = 303
Score = 70.5 bits (165), Expect = 4e-11
Identities = 52/138 (37%), Positives = 71/138 (51%)
Frame = +1
Query: 10 GLACGQDPVLVKGISQWVRKAIKIPFFVKLTPNITDIVSIAVAAYEGGANGVSAINTVSG 189
G+A G V + Q VR A K VKL+PN+TDI +A AA GA+ VS INT+ G
Sbjct: 137 GMAFGVTTKGVSEVVQAVRSAYKKTLIVKLSPNVTDIAEMARAAEANGADSVSLINTLLG 196
Query: 190 LMSVKADATPWPAVGKQKRTTYGGVSGNATRPIGLRAVSAVGNKXXXXXXXXXXXXDSAD 369
M++ A+ P + T GG+SG A +PI LR V V + D
Sbjct: 197 -MAIDAERKR-PILS----TVTGGMSGAAVKPIALRMVWQVAKAVNIPVIGLGGIMNWKD 250
Query: 370 SALQFILCGAPVVQICSA 423
A++F+L GA +QI +A
Sbjct: 251 -AVEFMLAGASAIQIGTA 267
>UniRef50_UPI00015BD53C Cluster: UPI00015BD53C related cluster; n=1;
unknown|Rep: UPI00015BD53C UniRef100 entry - unknown
Length = 310
Score = 69.7 bits (163), Expect = 6e-11
Identities = 51/156 (32%), Positives = 76/156 (48%), Gaps = 1/156 (0%)
Frame = +1
Query: 10 GLACGQDPVLVKGISQWVRKAIKIPFFVKLTPNITDIVSIAVAAYEGGANGVSAINTVSG 189
G+ GQDPV+++ + + ++ K P VKL+PN+TDI A E A+G+ INT+ G
Sbjct: 137 GVVFGQDPVVLRSLIEKIKSFAKKPLLVKLSPNVTDITEFAKICIEAKADGIVLINTLIG 196
Query: 190 LMSVKADATPWPAVGKQKRTTYGGVSGNATRPIGLRAVSAVGNKXXXXXXXXXXXXDSA- 366
+ + P+ A T GG+SG A PI +R + K S
Sbjct: 197 MKIDIYNERPFLA------TKTGGLSGPAILPIAVRMIWQTYEKYGKAIPIIGVGGISTY 250
Query: 367 DSALQFILCGAPVVQICSAVQNQDFTVVEDYITGLK 474
AL+ IL GA VQI +A + + + D I G+K
Sbjct: 251 VDALEHILAGASAVQIGTANFYKPLSPL-DVIEGIK 285
>UniRef50_Q1MQG1 Cluster: Dihydroorotate dehydrogenase; n=2;
Deltaproteobacteria|Rep: Dihydroorotate dehydrogenase -
Lawsonia intracellularis (strain PHE/MN1-00)
Length = 314
Score = 68.5 bits (160), Expect = 1e-10
Identities = 52/136 (38%), Positives = 67/136 (49%), Gaps = 1/136 (0%)
Frame = +1
Query: 10 GLACGQDPVLVKGISQWVRK-AIKIPFFVKLTPNITDIVSIAVAAYEGGANGVSAINTVS 186
G GQDP L +++ V K A P VKL+PN+TDI IA A GA+ +S INT++
Sbjct: 146 GTFFGQDPSLAAKVTEAVCKNAGSKPVMVKLSPNVTDITIIAKAVESAGADAISCINTLT 205
Query: 187 GLMSVKADATPWPAVGKQKRTTYGGVSGNATRPIGLRAVSAVGNKXXXXXXXXXXXXDSA 366
G+ D ++ T GG+SG +PI LR V V K SA
Sbjct: 206 GM---AVDIRKRKSL---LSTVIGGLSGPGIKPIALRCVWEV-CKAVNIPVIGIGGITSA 258
Query: 367 DSALQFILCGAPVVQI 414
L+FIL GA VQI
Sbjct: 259 RDVLEFILVGAHAVQI 274
>UniRef50_A7DP74 Cluster: Dihydroorotate dehydrogenase family
protein; n=1; Candidatus Nitrosopumilus maritimus
SCM1|Rep: Dihydroorotate dehydrogenase family protein -
Candidatus Nitrosopumilus maritimus SCM1
Length = 303
Score = 68.1 bits (159), Expect = 2e-10
Identities = 47/157 (29%), Positives = 76/157 (48%)
Frame = +1
Query: 1 AGMGLACGQDPVLVKGISQWVRKAIKIPFFVKLTPNITDIVSIAVAAYEGGANGVSAINT 180
A +GL G DP LVK I V+ + +P K+ T ++ A E G + ++AINT
Sbjct: 132 AKVGLEVGDDPELVKKIVTTVKNSTNVPVIAKVGLGTTHYLNTVGTAIESGIDAITAINT 191
Query: 181 VSGLMSVKADATPWPAVGKQKRTTYGGVSGNATRPIGLRAVSAVGNKXXXXXXXXXXXXD 360
V M++ + T P + + +GG+SG +PI LR V + +K
Sbjct: 192 VRS-MAIDVE-TQRPILSNK----FGGLSGTPIKPIALRCVYEISSK-YDIPIIGCGGIS 244
Query: 361 SADSALQFILCGAPVVQICSAVQNQDFTVVEDYITGL 471
+ + A++F L GA VQ+ SA+ + V + TG+
Sbjct: 245 TWEDAVEFFLAGASSVQLGSAIGDNWIDVFNEINTGI 281
>UniRef50_Q8KC29 Cluster: Dihydroorotate dehydrogenase; n=10;
Chlorobiaceae|Rep: Dihydroorotate dehydrogenase -
Chlorobium tepidum
Length = 305
Score = 66.9 bits (156), Expect = 4e-10
Identities = 48/137 (35%), Positives = 66/137 (48%)
Frame = +1
Query: 4 GMGLACGQDPVLVKGISQWVRKAIKIPFFVKLTPNITDIVSIAVAAYEGGANGVSAINTV 183
G + G P + I +RK + VKLTPN+T I +IA+AA E GA+ VS INTV
Sbjct: 137 GECMIMGVSPDATREIVSTLRKQTRRHLMVKLTPNVTSISAIALAAEEAGADSVSLINTV 196
Query: 184 SGLMSVKADATPWPAVGKQKRTTYGGVSGNATRPIGLRAVSAVGNKXXXXXXXXXXXXDS 363
G+ A + + GG+SG A +PI L V V +K S
Sbjct: 197 VGM------AVDYRKRKPLLKNVTGGLSGPAIKPIALAKVWEV-SKAVKIPIVGMGGIAS 249
Query: 364 ADSALQFILCGAPVVQI 414
A++F+L GA +QI
Sbjct: 250 FSDAMEFLLVGASAIQI 266
>UniRef50_A6L5H1 Cluster: Dihydroorotate dehydrogenase; n=1;
Bacteroides vulgatus ATCC 8482|Rep: Dihydroorotate
dehydrogenase - Bacteroides vulgatus (strain ATCC 8482 /
DSM 1447 / NCTC 11154)
Length = 303
Score = 66.9 bits (156), Expect = 4e-10
Identities = 51/138 (36%), Positives = 68/138 (49%)
Frame = +1
Query: 10 GLACGQDPVLVKGISQWVRKAIKIPFFVKLTPNITDIVSIAVAAYEGGANGVSAINTVSG 189
G+A G + + VR K VKL+PN+TDI IA AA GA+ VS INT+ G
Sbjct: 137 GMAFGVSACGCSEVVKAVRNVYKKTLIVKLSPNVTDITEIARAAEASGADSVSLINTLLG 196
Query: 190 LMSVKADATPWPAVGKQKRTTYGGVSGNATRPIGLRAVSAVGNKXXXXXXXXXXXXDSAD 369
M+V A+ P + T GG+SG A +PI LR V V D
Sbjct: 197 -MAVDAEKRR-PVLS----TITGGMSGAAVKPIALRMVWQVAKAVNIPVIGLGGIMGWKD 250
Query: 370 SALQFILCGAPVVQICSA 423
A++F+L GA +QI +A
Sbjct: 251 -AVEFMLAGATAIQIGTA 267
>UniRef50_Q8TXU6 Cluster: Dihydroorotate dehydrogenase; n=1;
Methanopyrus kandleri|Rep: Dihydroorotate dehydrogenase
- Methanopyrus kandleri
Length = 318
Score = 66.9 bits (156), Expect = 4e-10
Identities = 44/149 (29%), Positives = 73/149 (48%), Gaps = 3/149 (2%)
Frame = +1
Query: 4 GMGLACGQDPVLVKGISQWVRKAIKIPFFVKLTPNI--TDIVSIAVAAYEGGANGVSAIN 177
G G G DP V I++ +A P VKLTPN+ ++ +A AA + GA ++A+N
Sbjct: 134 GYGAELGSDPEAVAEITEAAVRAFDGPVSVKLTPNVDRETLLEVAAAAIDAGAEALTAVN 193
Query: 178 TVSGLMSVKADATPWPAVGKQKRTTYGGVSGNATRPIGLRAVSAVGNK-XXXXXXXXXXX 354
T+ + + T P +G GG+SG A +PI LR V+ + +
Sbjct: 194 TLGPGLRIDL-RTASPVLG----AGVGGLSGPALKPIALRVVADLALEFGEEVEIIGVGG 248
Query: 355 XDSADSALQFILCGAPVVQICSAVQNQDF 441
+ + ++F+ GA VQ+ +A + +DF
Sbjct: 249 IRNGEDVVEFLFAGAKAVQVATAAREKDF 277
>UniRef50_A5FPW7 Cluster: Dihydroorotate dehydrogenase family
protein; n=21; Bacteria|Rep: Dihydroorotate
dehydrogenase family protein - Dehalococcoides sp. BAV1
Length = 324
Score = 66.5 bits (155), Expect = 6e-10
Identities = 49/162 (30%), Positives = 78/162 (48%), Gaps = 1/162 (0%)
Frame = +1
Query: 22 GQDPVLVKGISQWVRKAIKIPFFVKLTPNITDIVSIAVAAYEGGANGVSAINTVSGL-MS 198
G P ++ VR A +P VKLTPN + I +A A + GA+ +S INT+ G+ +
Sbjct: 162 GSSPESAAKVTDVVRNATTLPLIVKLTPNTSSITELAKAVADAGADAISLINTLRGMRID 221
Query: 199 VKADATPWPAVGKQKRTTYGGVSGNATRPIGLRAVSAVGNKXXXXXXXXXXXXDSADSAL 378
+K P +G GG+SG A +P+ + V V +A+ AL
Sbjct: 222 IKKRR---PVLGNHT----GGLSGPAIKPVAISMVYQVAGAVNVPVIGGGGIM-NAEDAL 273
Query: 379 QFILCGAPVVQICSAVQNQDFTVVEDYITGLKALLYLRSRGL 504
+F++ GA +QI +A + D + GL+A Y ++ GL
Sbjct: 274 EFLMAGATAIQIGTA-NLVNPRAPMDILEGLEA--YAKAEGL 312
>UniRef50_A0RV22 Cluster: Dihydroorotate dehydrogenase; n=1;
Cenarchaeum symbiosum|Rep: Dihydroorotate dehydrogenase
- Cenarchaeum symbiosum
Length = 281
Score = 66.5 bits (155), Expect = 6e-10
Identities = 48/141 (34%), Positives = 70/141 (49%)
Frame = +1
Query: 1 AGMGLACGQDPVLVKGISQWVRKAIKIPFFVKLTPNITDIVSIAVAAYEGGANGVSAINT 180
A +GL G DP LV I ++A +P F K+ T + A AA E GA+ ++AINT
Sbjct: 112 AKVGLEVGDDPGLVGEIVSAAKRAADVPVFAKVGLGSTHYIKTAGAAAEAGADAITAINT 171
Query: 181 VSGLMSVKADATPWPAVGKQKRTTYGGVSGNATRPIGLRAVSAVGNKXXXXXXXXXXXXD 360
V MS+ +A P + +GG+SG RPI +R V + +K
Sbjct: 172 VRA-MSIDVEAKK-PVLS----NGFGGLSGPPIRPIAVRCVWELASK-YDVPVIGCGGVS 224
Query: 361 SADSALQFILCGAPVVQICSA 423
S + A++ +L GA VQ+ SA
Sbjct: 225 SWEDAIEMMLAGACAVQVGSA 245
>UniRef50_Q1IUQ6 Cluster: Dihydroorotate dehydrogenase family
protein; n=3; Bacteria|Rep: Dihydroorotate dehydrogenase
family protein - Acidobacteria bacterium (strain
Ellin345)
Length = 321
Score = 66.1 bits (154), Expect = 8e-10
Identities = 43/138 (31%), Positives = 68/138 (49%)
Frame = +1
Query: 10 GLACGQDPVLVKGISQWVRKAIKIPFFVKLTPNITDIVSIAVAAYEGGANGVSAINTVSG 189
G+ G DP L+ + +KA P VKL+PN+T I +A A + GA+ +S +NT G
Sbjct: 154 GMTFGADPTLLAEVVTVAKKAATRPLIVKLSPNVTSIPQMAKIAQDAGADAISLVNTFVG 213
Query: 190 LMSVKADATPWPAVGKQKRTTYGGVSGNATRPIGLRAVSAVGNKXXXXXXXXXXXXDSAD 369
M++ + T P + G+SG A +PI LR V K +A+
Sbjct: 214 -MAIDVE-TRKPRIS----NIVAGLSGPAIKPIALRMVYEAA-KTVTIPVIGIGGISTAE 266
Query: 370 SALQFILCGAPVVQICSA 423
++F+L GA V++ +A
Sbjct: 267 DIVEFMLAGATAVEVGTA 284
>UniRef50_Q2NEG1 Cluster: PyrD; n=1; Methanosphaera stadtmanae DSM
3091|Rep: PyrD - Methanosphaera stadtmanae (strain DSM
3091)
Length = 306
Score = 65.3 bits (152), Expect = 1e-09
Identities = 45/142 (31%), Positives = 70/142 (49%), Gaps = 1/142 (0%)
Frame = +1
Query: 4 GMGLACGQDPVLVKGISQWVRKAIK-IPFFVKLTPNITDIVSIAVAAYEGGANGVSAINT 180
G G G++P L I V+ IK +P VKLTPN+TDI IA AA + GA+ ++ IN+
Sbjct: 133 GFGSNIGENPELTHDIVSSVKDNIKDVPIIVKLTPNVTDITEIAKAAEDAGADALTLINS 192
Query: 181 VSGLMSVKADATPWPAVGKQKRTTYGGVSGNATRPIGLRAVSAVGNKXXXXXXXXXXXXD 360
V + + T P + +GG++G +PI L+ V
Sbjct: 193 VGPGLRIDY-KTARPIL----NNVFGGIAGPMIKPIALKCVYKTYETVDIPLFGVGGIRT 247
Query: 361 SADSALQFILCGAPVVQICSAV 426
D AL+F+ GA ++QI +++
Sbjct: 248 YKD-ALEFLYAGASLLQIGTSI 268
>UniRef50_A0Z3E6 Cluster: Dihydroorotate
dehydrogenase/oxidoreductase, FAD-binding protein; n=5;
Bacteria|Rep: Dihydroorotate
dehydrogenase/oxidoreductase, FAD-binding protein -
marine gamma proteobacterium HTCC2080
Length = 551
Score = 64.9 bits (151), Expect = 2e-09
Identities = 50/159 (31%), Positives = 74/159 (46%), Gaps = 2/159 (1%)
Frame = +1
Query: 1 AGMGLACGQDPVLVKGISQWVRKAIKIPFFVKLTPNITDIVSIAVAAYEGGANGVSAINT 180
+G G+A GQDP +V I V++ + P KLTPN+T+I I AA + GA+G+ AINT
Sbjct: 132 SGYGMAMGQDPKIVHEIIAAVKQVVSKPVIPKLTPNVTNIAEIGQAALDAGADGLCAINT 191
Query: 181 VS-GLMSVKADATPWPAVGKQKRTTYGGVSGNATRPIGLRAVSAVGNKXXXXXXXXXXXX 357
V G +A V GG+SG P L+ + +
Sbjct: 192 VGPGYTESHGEAVLSNGV--------GGMSGKGVLPTALKCIRELRAITDKPIIGCGGLS 243
Query: 358 DSAD-SALQFILCGAPVVQICSAVQNQDFTVVEDYITGL 471
+AD +A + GA +V I SA+ D ++ Y + L
Sbjct: 244 SAADVNAAKH--AGATIVGIGSALSGMDTEDLQRYFSTL 280
>UniRef50_Q73P17 Cluster: Dihydroorotate
dehydrogenase/oxidoreductase, FAD-binding; n=1;
Treponema denticola|Rep: Dihydroorotate
dehydrogenase/oxidoreductase, FAD-binding - Treponema
denticola
Length = 591
Score = 62.9 bits (146), Expect = 7e-09
Identities = 37/107 (34%), Positives = 58/107 (54%), Gaps = 3/107 (2%)
Frame = +1
Query: 1 AGMGLACGQDPVLVKGISQWVRKAIK---IPFFVKLTPNITDIVSIAVAAYEGGANGVSA 171
AG G + G DP + + ++KA+ +P FVKLTPN+ DI +IA A E GA+G++A
Sbjct: 147 AGFGASIGCDPAIAAEYVKIIKKALPDCAVPIFVKLTPNVEDIGAIASAVIEAGADGITA 206
Query: 172 INTVSGLMSVKADATPWPAVGKQKRTTYGGVSGNATRPIGLRAVSAV 312
INTV + ++ + + + K GG+SG P L + +
Sbjct: 207 INTVGPKVYIEPHS--GKPILQNKLGGKGGMSGAWVFPRALECIGQI 251
>UniRef50_A6LJ97 Cluster: Dihydroorotate dehydrogenase family
protein; n=1; Thermosipho melanesiensis BI429|Rep:
Dihydroorotate dehydrogenase family protein -
Thermosipho melanesiensis BI429
Length = 360
Score = 62.1 bits (144), Expect = 1e-08
Identities = 39/134 (29%), Positives = 62/134 (46%)
Frame = +1
Query: 22 GQDPVLVKGISQWVRKAIKIPFFVKLTPNITDIVSIAVAAYEGGANGVSAINTVSGLMSV 201
G+D + I + +RK P F+KL+P+I D V E GANG+ AIN+ M +
Sbjct: 128 GKDYNTIANIVKAIRKNTNKPIFMKLSPHIPDPVEFTKTILENGANGIVAINSWGPTMKI 187
Query: 202 KADATPWPAVGKQKRTTYGGVSGNATRPIGLRAVSAVGNKXXXXXXXXXXXXDSADSALQ 381
+G +K + +SG +PI L V + + SA+ ++
Sbjct: 188 DIKNRK-TLIGNEKGQVW--LSGPVIKPIALSIVKTIRDAFPDITIIGVGGIKSAEDVIE 244
Query: 382 FILCGAPVVQICSA 423
F+L GA VQ+ S+
Sbjct: 245 FLLSGADAVQLLSS 258
>UniRef50_Q891J3 Cluster: Dihydroorotate dehydrogenase; n=16;
Bacteria|Rep: Dihydroorotate dehydrogenase - Clostridium
tetani
Length = 304
Score = 61.7 bits (143), Expect = 2e-08
Identities = 48/165 (29%), Positives = 78/165 (47%)
Frame = +1
Query: 10 GLACGQDPVLVKGISQWVRKAIKIPFFVKLTPNITDIVSIAVAAYEGGANGVSAINTVSG 189
G+A G + + V+K K P VKL+PN DIV +AV EGGA +S +NT
Sbjct: 140 GMAFGIKSKVAYDVVSRVKKICKKPLIVKLSPNAEDIVDMAVKCCEGGAEAISLVNT--- 196
Query: 190 LMSVKADATPWPAVGKQKRTTYGGVSGNATRPIGLRAVSAVGNKXXXXXXXXXXXXDSAD 369
KA A + G+SG A +PI LR V V K ++
Sbjct: 197 ---FKAMAVDIKSRKSVFNNITAGLSGVAIKPIALRMVYEV-CKNVNVPVIGLGGINNWQ 252
Query: 370 SALQFILCGAPVVQICSAVQNQDFTVVEDYITGLKALLYLRSRGL 504
A++FI+ GA +Q+ +A ++ ++ + G+++ Y++ G+
Sbjct: 253 DAIEFIMVGATAIQVGTANFINPYSSIK-IVHGIES--YMKKEGI 294
>UniRef50_Q9YFI6 Cluster: Dihydroorotate dehydrogenase; n=3;
Desulfurococcales|Rep: Dihydroorotate dehydrogenase -
Aeropyrum pernix
Length = 306
Score = 61.7 bits (143), Expect = 2e-08
Identities = 49/163 (30%), Positives = 76/163 (46%)
Frame = +1
Query: 1 AGMGLACGQDPVLVKGISQWVRKAIKIPFFVKLTPNITDIVSIAVAAYEGGANGVSAINT 180
AG GL GQDP V + V ++IP KL + +V A A E GA G++ IN+
Sbjct: 136 AGGGLELGQDPAAVASVVSAVASTLRIPVIAKLGYS-DRLVDAASKALEAGARGLTLINS 194
Query: 181 VSGLMSVKADATPWPAVGKQKRTTYGGVSGNATRPIGLRAVSAVGNKXXXXXXXXXXXXD 360
+ M + A P +G + GG+SG PI +RAV V + +
Sbjct: 195 MRA-MKIDVYAKK-PVLGNR----VGGLSGKPIHPIAVRAVYEVYGE-TRADIFAAGGVE 247
Query: 361 SADSALQFILCGAPVVQICSAVQNQDFTVVEDYITGLKALLYL 489
S + A++F L GA VQ+ +A V+ + G++ L++
Sbjct: 248 SWEDAVEFYLAGAKAVQVGAAFITIGPHVLRSIVEGVRRYLWV 290
>UniRef50_A5NSG9 Cluster: Dihydroorotate dehydrogenase family
protein; n=5; Proteobacteria|Rep: Dihydroorotate
dehydrogenase family protein - Methylobacterium sp. 4-46
Length = 351
Score = 60.1 bits (139), Expect = 5e-08
Identities = 48/152 (31%), Positives = 75/152 (49%)
Frame = +1
Query: 49 ISQWVRKAIKIPFFVKLTPNITDIVSIAVAAYEGGANGVSAINTVSGLMSVKADATPWPA 228
+++ +R A +P +VKLTPN ++ +A AA E GA+ V NT+ M++ T P
Sbjct: 183 VTRQLRAATDLPLWVKLTPNTAEMPEVARAAQEAGADAVVVANTIPS-MAIDL-RTFKPC 240
Query: 229 VGKQKRTTYGGVSGNATRPIGLRAVSAVGNKXXXXXXXXXXXXDSADSALQFILCGAPVV 408
+G GG+SG A +PI LR V K +A+ A +++L GA V
Sbjct: 241 LG----NIMGGLSGPAVKPIVLRHVYLCA-KAVTIPVIGCGGIGTAEDAAEYMLAGAAAV 295
Query: 409 QICSAVQNQDFTVVEDYITGLKALLYLRSRGL 504
Q+ +A Q + I GL+A + RG+
Sbjct: 296 QVGTATFLQP-AAMTTIIDGLEA--FCAQRGI 324
>UniRef50_A3DL41 Cluster: Dihydroorotate dehydrogenase family
protein; n=1; Staphylothermus marinus F1|Rep:
Dihydroorotate dehydrogenase family protein -
Staphylothermus marinus (strain ATCC 43588 / DSM 3639 /
F1)
Length = 406
Score = 56.4 bits (130), Expect = 6e-07
Identities = 45/179 (25%), Positives = 77/179 (43%)
Frame = +1
Query: 22 GQDPVLVKGISQWVRKAIKIPFFVKLTPNITDIVSIAVAAYEGGANGVSAINTVSGLMSV 201
G+D V ++ +R+ + IP F KL+P +I + + G +G+ A NT+ + +
Sbjct: 163 GKDYRPVVEAAKALREVVDIPIFAKLSPFTPNIPELVKELEKVGVDGIVATNTIGPALHI 222
Query: 202 KADATPWPAVGKQKRTTYGGVSGNATRPIGLRAVSAVGNKXXXXXXXXXXXXDSADSALQ 381
+ T P VG YG +SG A +P+ L AV A K ++
Sbjct: 223 DIE-TGLPIVGGP--NGYGWMSGPALKPLAL-AVVAEAAKNTHLPVIGVGGISKGTDVIE 278
Query: 382 FILCGAPVVQICSAVQNQDFTVVEDYITGLKALLYLRSRGLDGWTGQSPPTFKHQKGKP 558
+ + GA VQIC+A + V +++ +L+ G D K+ K +P
Sbjct: 279 YFMAGASAVQICTAALIEGLGVFRRIEKEIES--WLKRHGYDSILDVKGKALKYLKPEP 335
>UniRef50_O08358 Cluster: Dihydroorotate dehydrogenase; n=4;
Sulfolobaceae|Rep: Dihydroorotate dehydrogenase -
Sulfolobus acidocaldarius
Length = 291
Score = 56.4 bits (130), Expect = 6e-07
Identities = 45/155 (29%), Positives = 73/155 (47%)
Frame = +1
Query: 40 VKGISQWVRKAIKIPFFVKLTPNITDIVSIAVAAYEGGANGVSAINTVSGLMSVKADATP 219
V+ I + V+ +K P FVKL P +IV IA A GA+G++ INT+ G++ D P
Sbjct: 135 VEEIVKNVKSIVKKPVFVKLGP-WDNIVEIAGRALSAGADGLTLINTLKGMLIDVEDFKP 193
Query: 220 WPAVGKQKRTTYGGVSGNATRPIGLRAVSAVGNKXXXXXXXXXXXXDSADSALQFILCGA 399
+ G GG+SG + +R + V + D D A++ I GA
Sbjct: 194 ILSYGT------GGISGKCIHALAVRVIHDVFKEYEPEIIGVGGVFDWRD-AIELISVGA 246
Query: 400 PVVQICSAVQNQDFTVVEDYITGLKALLYLRSRGL 504
+V + + + + F V+ + G+ YL +GL
Sbjct: 247 KLVGLGTVLVEKGFDVIREIREGIGT--YLEEKGL 279
>UniRef50_O29513 Cluster: Dihydroorotate dehydrogenase; n=1;
Archaeoglobus fulgidus|Rep: Dihydroorotate dehydrogenase
- Archaeoglobus fulgidus
Length = 299
Score = 53.2 bits (122), Expect = 6e-06
Identities = 45/141 (31%), Positives = 64/141 (45%)
Frame = +1
Query: 4 GMGLACGQDPVLVKGISQWVRKAIKIPFFVKLTPNITDIVSIAVAAYEGGANGVSAINTV 183
G GL G D L I + ++ K P F KL+ + D + +A + G +G++ NT+
Sbjct: 133 GAGLDIGMDLELSAAIVEELKGKTKNPVFAKLSA-MHDYLKLAKVLEDAGVDGITISNTL 191
Query: 184 SGLMSVKADATPWPAVGKQKRTTYGGVSGNATRPIGLRAVSAVGNKXXXXXXXXXXXXDS 363
G+ K D V GGVSG A +PI L+ V + K S
Sbjct: 192 RGM---KIDIMSGKPV---LSNLSGGVSGPAIKPIALKCVYDL-YKEIEVPIVGCGGITS 244
Query: 364 ADSALQFILCGAPVVQICSAV 426
+ L+FI+ GA VQI SAV
Sbjct: 245 FEDVLEFIMAGARAVQIGSAV 265
>UniRef50_A4M861 Cluster: Dihydroorotate dehydrogenase family
protein; n=2; Bacteria|Rep: Dihydroorotate dehydrogenase
family protein - Petrotoga mobilis SJ95
Length = 363
Score = 52.0 bits (119), Expect = 1e-05
Identities = 37/135 (27%), Positives = 65/135 (48%), Gaps = 1/135 (0%)
Frame = +1
Query: 22 GQDPVLVKGISQWVRKAIKIPFFVKLTPNITDIVSIAVAAYEGGANGVSAINTVSGLMSV 201
G DP + + ++ +P VKL+P + DI A A GA+G+ IN+ + +
Sbjct: 128 GNDPTPMINSIRAAKETTDLPVMVKLSPQV-DIPKFAKEAENAGADGLVLINSFGPTLDI 186
Query: 202 KADATPWPAVGKQKRTTYGGVSGNATRPIGLRAV-SAVGNKXXXXXXXXXXXXDSADSAL 378
++ P +G + +G +SG A P+ LR+V AV + ++ A+
Sbjct: 187 DLESGK-PLLGSENG--FGWLSGQAIFPLALRSVFEAV--RSVNIPVVGVGGINTGKEAI 241
Query: 379 QFILCGAPVVQICSA 423
+ I+ GA VQ+C+A
Sbjct: 242 KMIMAGAQAVQVCTA 256
>UniRef50_A2EKA7 Cluster: Dihydroorotate dehydrogenase family
protein; n=3; Trichomonas vaginalis G3|Rep:
Dihydroorotate dehydrogenase family protein -
Trichomonas vaginalis G3
Length = 365
Score = 51.6 bits (118), Expect = 2e-05
Identities = 34/114 (29%), Positives = 55/114 (48%)
Frame = +1
Query: 82 PFFVKLTPNITDIVSIAVAAYEGGANGVSAINTVSGLMSVKADATPWPAVGKQKRTTYGG 261
P +VKL+P D A AA GA G+ +N+ +++ + P +G + YG
Sbjct: 154 PVYVKLSP-FRDAPIAAKAAKAAGATGLVCVNSFGPTLALDIERKGAPFMGSTSK--YGW 210
Query: 262 VSGNATRPIGLRAVSAVGNKXXXXXXXXXXXXDSADSALQFILCGAPVVQICSA 423
VSG A +P+ LR V V + + D A++F++ GA + IC+A
Sbjct: 211 VSGPAIKPLALRVVYDVCKEVDLPVVGVGGISNGRD-AIEFLMAGAQALGICTA 263
>UniRef50_Q1AVZ1 Cluster: Dihydroorotate dehydrogenase family
protein; n=1; Rubrobacter xylanophilus DSM 9941|Rep:
Dihydroorotate dehydrogenase family protein -
Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 304
Score = 48.8 bits (111), Expect = 1e-04
Identities = 41/120 (34%), Positives = 59/120 (49%)
Frame = +1
Query: 64 RKAIKIPFFVKLTPNITDIVSIAVAAYEGGANGVSAINTVSGLMSVKADATPWPAVGKQK 243
R A +P KL + +V A+AA GA+G++ +NTV L +V A A ++
Sbjct: 153 RAAPDVPLLAKLA--LEGVVQNALAAEAAGADGLTVMNTVPAL-AVDARA--------RR 201
Query: 244 RTTYGGVSGNATRPIGLRAVSAVGNKXXXXXXXXXXXXDSADSALQFILCGAPVVQICSA 423
GG+SG A +P+ LRAV V + AD A +F+L GA VQ+ SA
Sbjct: 202 VLLRGGLSGPAIKPLALRAVYDVASAAEIPVVGCGGVCSGADVA-EFMLAGARAVQVGSA 260
>UniRef50_A4FBL7 Cluster: Dihydroorotate dehydrogenase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep:
Dihydroorotate dehydrogenase - Saccharopolyspora
erythraea (strain NRRL 23338)
Length = 338
Score = 47.2 bits (107), Expect = 4e-04
Identities = 35/115 (30%), Positives = 57/115 (49%), Gaps = 1/115 (0%)
Frame = +1
Query: 82 PFFVKLTPNITDIVSIAVAAYEGGANGVSAINTVSGLMSVKADATPWPAVGKQK-RTTYG 258
P +KL+P+ D ++ A A + G + ++AINTV GL + D P G+ + +G
Sbjct: 198 PVILKLSPDY-DYLAHARLAAKHGVSALTAINTVKGL---RLD----PETGQPLLKNRFG 249
Query: 259 GVSGNATRPIGLRAVSAVGNKXXXXXXXXXXXXDSADSALQFILCGAPVVQICSA 423
G+SG A +PIGLR V+ + + + D ++ GA V + SA
Sbjct: 250 GLSGRAIKPIGLRVVAELRDAGVKLPIIATGGIRTFDDCREYFWAGADAVSLGSA 304
>UniRef50_UPI0000F1DE0E Cluster: PREDICTED: similar to
Dihydropyrimidine dehydrogenase; n=1; Danio rerio|Rep:
PREDICTED: similar to Dihydropyrimidine dehydrogenase -
Danio rerio
Length = 403
Score = 46.4 bits (105), Expect = 7e-04
Identities = 24/49 (48%), Positives = 29/49 (59%)
Frame = +1
Query: 268 GNATRPIGLRAVSAVGNKXXXXXXXXXXXXDSADSALQFILCGAPVVQI 414
GNA RPI LRAVSA+ DSA+SALQF+ GA V+Q+
Sbjct: 341 GNAIRPIALRAVSAIAKALPDFPILATGGIDSAESALQFLHVGATVLQV 389
>UniRef50_A6Q8G0 Cluster: Dihydroorotate dehydrogenase; n=4;
Epsilonproteobacteria|Rep: Dihydroorotate dehydrogenase
- Sulfurovum sp. (strain NBC37-1)
Length = 354
Score = 41.1 bits (92), Expect = 0.025
Identities = 39/161 (24%), Positives = 69/161 (42%), Gaps = 3/161 (1%)
Frame = +1
Query: 10 GLACGQDPVLVKGISQWVRKAIKIPFFVKLTPNIT--DIVSIAVAAYEGGANGVSAINTV 183
GL Q+ +K I ++ + P +K+ P++T D +++ A + GA G+ A NT
Sbjct: 189 GLRDLQNEQFIKDIFAMAKRITEQPVLLKIAPDMTHEDAIALCNTAVDAGAAGIIATNT- 247
Query: 184 SGLMSVKADATPWPAVGKQKRTTYGGVSGNATRPIGLRAVSAVGNKXXXXXXXXXXXX-D 360
++ TP +GG+SG + A+G + D
Sbjct: 248 ----TIDYSLTP-------HAKDFGGISGALLTEKSYQLFKAIGKELYGKTLLISVGGID 296
Query: 361 SADSALQFILCGAPVVQICSAVQNQDFTVVEDYITGLKALL 483
SA+ A + I GA +VQ+ S + + ++ + GL LL
Sbjct: 297 SAEEAYRRIKAGASLVQVYSMLIYKGPALIREINEGLIKLL 337
>UniRef50_Q7U3U2 Cluster: Dihydroorotate dehydrogenase; n=25;
Cyanobacteria|Rep: Dihydroorotate dehydrogenase -
Synechococcus sp. (strain WH8102)
Length = 396
Score = 38.3 bits (85), Expect = 0.18
Identities = 37/137 (27%), Positives = 58/137 (42%), Gaps = 3/137 (2%)
Frame = +1
Query: 82 PFFVKLTPNITD--IVSIAVAAYEGGANGVSAINTVSGLMSVKADATPWPAVGKQKRTTY 255
P VK+ P++ D I IA A+E G GV A+NT L + + G+
Sbjct: 235 PLLVKIAPDLEDEAIDGIARLAFEEGLAGVIAVNT--SLDRLGLEQRRLLQTGRTLAEEA 292
Query: 256 GGVSGNATRPIGLRAVSAV-GNKXXXXXXXXXXXXDSADSALQFILCGAPVVQICSAVQN 432
GG+SG R L + + + DSA+ A + I GA ++Q+ +
Sbjct: 293 GGLSGAPLRQRALEVIRRLRASAGPALTLIGVGGIDSAEIAWERITAGASLIQLYTGWIF 352
Query: 433 QDFTVVEDYITGLKALL 483
Q +V + GL+ L
Sbjct: 353 QGPELVPRILEGLQLQL 369
>UniRef50_Q7N0H1 Cluster: Similar to dihydroorotate dehydrogenase
PyrD; n=1; Photorhabdus luminescens subsp.
laumondii|Rep: Similar to dihydroorotate dehydrogenase
PyrD - Photorhabdus luminescens subsp. laumondii
Length = 289
Score = 37.9 bits (84), Expect = 0.24
Identities = 31/141 (21%), Positives = 61/141 (43%)
Frame = +1
Query: 31 PVLVKGISQWVRKAIKIPFFVKLTPNITDIVSIAVAAYEGGANGVSAINTVSGLMSVKAD 210
P V ++ V++ PF VKL+ ++ AA EGGA+ ++ +T+SG+ A+
Sbjct: 142 PERVFNYTKVVKERTNTPFAVKLSLG-DNLYGRVQAAVEGGADAITLSDTISGIAFDTAN 200
Query: 211 ATPWPAVGKQKRTTYGGVSGNATRPIGLRAVSAVGNKXXXXXXXXXXXXDSADSALQFIL 390
G+ G SG +P+ L A+ + + + +++L
Sbjct: 201 -------GEALLNGVCGYSGPGIKPMVLAAIYNLRKRGVTIPILGSGGVQDGNDVHEYLL 253
Query: 391 CGAPVVQICSAVQNQDFTVVE 453
GA VQ+ +A+ + ++
Sbjct: 254 AGANTVQVYTALHRHMYKTLQ 274
>UniRef50_Q5PBF6 Cluster: Dihydroorotate dehydrogenase; n=12;
Rickettsiales|Rep: Dihydroorotate dehydrogenase -
Anaplasma marginale (strain St. Maries)
Length = 389
Score = 37.1 bits (82), Expect = 0.41
Identities = 39/151 (25%), Positives = 65/151 (43%), Gaps = 3/151 (1%)
Frame = +1
Query: 40 VKGISQWVRKAIKIPFFVKLTPNITDIV--SIAVAAYEGGANGVSAINTVSGLMSVKADA 213
V+ + V +A +P F+K+ P+I+D + IA + +G+ NT + L + D
Sbjct: 230 VRDARRSVDQAESVPIFLKIAPDISDELKQDIAEEIVKHKISGLIVSNTTTDLSLLGKD- 288
Query: 214 TPWPAVGKQKRTTYGGVSGNATRPIGLRAVSAVGN-KXXXXXXXXXXXXDSADSALQFIL 390
+ K T GG+SG + +S + + S ALQ I
Sbjct: 289 -------RNKSITQGGLSGRPLFDLSTTVLSEMYSLLRDKVILIGCGGVSSGAQALQKIK 341
Query: 391 CGAPVVQICSAVQNQDFTVVEDYITGLKALL 483
GA +VQ+ +A+ + F VV+ L LL
Sbjct: 342 AGASLVQLYTALVYEGFGVVKKINMELAELL 372
>UniRef50_A6C020 Cluster: Putative uncharacterized protein; n=1;
Planctomyces maris DSM 8797|Rep: Putative
uncharacterized protein - Planctomyces maris DSM 8797
Length = 641
Score = 36.7 bits (81), Expect = 0.55
Identities = 17/58 (29%), Positives = 34/58 (58%)
Frame = +1
Query: 25 QDPVLVKGISQWVRKAIKIPFFVKLTPNITDIVSIAVAAYEGGANGVSAINTVSGLMS 198
+DPV +KG+S++V +A K+ + N D+++++ A ANG + +G+M+
Sbjct: 153 KDPVALKGLSRFVEEANKLTPKPRFVVNSGDLLNLSKALLSSPANGRAGFQNYTGIMN 210
>UniRef50_A3DM44 Cluster: Dihydroorotate dehydrogenase family
protein; n=1; Staphylothermus marinus F1|Rep:
Dihydroorotate dehydrogenase family protein -
Staphylothermus marinus (strain ATCC 43588 / DSM 3639 /
F1)
Length = 301
Score = 35.9 bits (79), Expect = 0.96
Identities = 30/116 (25%), Positives = 52/116 (44%), Gaps = 1/116 (0%)
Frame = +1
Query: 157 NGVSAINTVSGLMSVKADATPWPAVGKQKRTT-YGGVSGNATRPIGLRAVSAVGNKXXXX 333
NGV A+ ++ L + D VGK T +GG+SG A P+ + +V V +
Sbjct: 179 NGVDAVVLINTLPGMFIDVY----VGKPVLTHGFGGLSGPAIHPVAVYSVYKVYEELGAE 234
Query: 334 XXXXXXXXDSADSALQFILCGAPVVQICSAVQNQDFTVVEDYITGLKALLYLRSRG 501
D S ++ +L GA +QI + + +V + + G+K Y+ +G
Sbjct: 235 IIGVGGVIDWKTS-VELLLAGAKAIQIGTGFYMVGYNIVNNILDGIKK--YMEEKG 287
>UniRef50_Q5B5Z0 Cluster: Putative uncharacterized protein; n=1;
Emericella nidulans|Rep: Putative uncharacterized
protein - Emericella nidulans (Aspergillus nidulans)
Length = 523
Score = 35.1 bits (77), Expect = 1.7
Identities = 17/36 (47%), Positives = 21/36 (58%)
Frame = +2
Query: 215 HLGLPSVNKNAQLTAAYRGTRLVQSDCGQSLRSEIN 322
H GL S NK A L A G V +DCG+S+R I+
Sbjct: 97 HCGLFSANKLAMLAAVGEGYAAVSTDCGRSMREGID 132
>UniRef50_Q4J443 Cluster: Dihydroorotate dehydrogenase precursor;
n=1; Azotobacter vinelandii AvOP|Rep: Dihydroorotate
dehydrogenase precursor - Azotobacter vinelandii AvOP
Length = 332
Score = 34.3 bits (75), Expect = 2.9
Identities = 16/39 (41%), Positives = 24/39 (61%)
Frame = +1
Query: 61 VRKAIKIPFFVKLTPNITDIVSIAVAAYEGGANGVSAIN 177
VR+ +KIP VK+ P + I ++A EGGA+G+ N
Sbjct: 158 VRRTVKIPVAVKMPPYFSAIGNMASRLLEGGADGLVIFN 196
>UniRef50_Q8EYC6 Cluster: Dihydroorotate dehydrogenase; n=4;
Leptospira|Rep: Dihydroorotate dehydrogenase -
Leptospira interrogans
Length = 382
Score = 33.9 bits (74), Expect = 3.9
Identities = 36/129 (27%), Positives = 56/129 (43%), Gaps = 3/129 (2%)
Frame = +1
Query: 37 LVKGISQWVRKAIKIPFFVKLTPNI--TDIVSIAVAAYEGGANGVSAINTVSGLMSVKAD 210
L++GI + + K KIP FVK P++ ++ ++ + NGV NT +K
Sbjct: 217 LIQGIRKDLGKNFKIPLFVKFAPDMETKELEALLETSLSLKINGVVLTNTTIDKSCLK-- 274
Query: 211 ATPWPAVGKQKRTTYGGVSGNATRPIGLRAVS-AVGNKXXXXXXXXXXXXDSADSALQFI 387
+P V K+ GG+SG + V A DS +AL+ I
Sbjct: 275 --NYPNVEKE-----GGLSGTPLKNRSTEFVRIAYRILKRRIPIIGVGGIDSEKTALEKI 327
Query: 388 LCGAPVVQI 414
L GA ++QI
Sbjct: 328 LAGADLIQI 336
>UniRef50_A2U3Q1 Cluster: Manganese transporter; n=7; Bacteria|Rep:
Manganese transporter - Polaribacter dokdonensis MED152
Length = 408
Score = 33.9 bits (74), Expect = 3.9
Identities = 19/52 (36%), Positives = 31/52 (59%), Gaps = 3/52 (5%)
Frame = +1
Query: 43 KGISQWVRKAIKIPFFVK-LTPNITDIVSIAVAAYEGG--ANGVSAINTVSG 189
KG+S+ +R+ IK+PF + +T I + I A+YE G + G+ + TV G
Sbjct: 66 KGLSEVIREEIKVPFLKQFITLLILGAIVIGNASYEAGNISGGILGLETVFG 117
>UniRef50_A2YPF0 Cluster: Putative uncharacterized protein; n=1;
Oryza sativa (indica cultivar-group)|Rep: Putative
uncharacterized protein - Oryza sativa subsp. indica
(Rice)
Length = 109
Score = 33.9 bits (74), Expect = 3.9
Identities = 17/47 (36%), Positives = 23/47 (48%), Gaps = 2/47 (4%)
Frame = +1
Query: 148 GGANGVSAINTVSGLMSVKADAT--PWPAVGKQKRTTYGGVSGNATR 282
GG G SG + ++ PWPA G+ + GG+SGNA R
Sbjct: 40 GGGVGADDAEGGSGQSRPRRSSSRPPWPAAGRPEAAAAGGISGNAPR 86
>UniRef50_A6SLQ0 Cluster: Putative uncharacterized protein; n=1;
Botryotinia fuckeliana B05.10|Rep: Putative
uncharacterized protein - Botryotinia fuckeliana B05.10
Length = 342
Score = 33.9 bits (74), Expect = 3.9
Identities = 26/91 (28%), Positives = 41/91 (45%), Gaps = 2/91 (2%)
Frame = +1
Query: 46 GISQWVRKAIKIPFFVKLTPNITDIVS-IAVAAYEGGANGVSAINTVSGLMS-VKADATP 219
G + + IK P + + ++VS + A G N +S I T + L S + D
Sbjct: 190 GTTNRIHVGIKTPPYT-YSEQFKNLVSALEFGALPSGENAISFITTTNTLGSCLIVDDLG 248
Query: 220 WPAVGKQKRTTYGGVSGNATRPIGLRAVSAV 312
PA+G GG++G+A PI L V +
Sbjct: 249 NPALGSSNGEGIGGMAGDALHPIALGNVKTI 279
>UniRef50_Q6AE78 Cluster: Dihydroorotate dehydrogenase; n=6;
Actinomycetales|Rep: Dihydroorotate dehydrogenase -
Leifsonia xyli subsp. xyli
Length = 343
Score = 33.9 bits (74), Expect = 3.9
Identities = 36/138 (26%), Positives = 55/138 (39%), Gaps = 3/138 (2%)
Frame = +1
Query: 76 KIPFFVKLTPNITD--IVSIAVAAYEGGANGVSAINTVSGLMSVKADATPWPAVGKQKRT 249
K P VK+ P++TD IV++A A E G G+ A NT + +D A G
Sbjct: 209 KKPLLVKIAPDLTDEQIVAVARLAVELGLAGIIATNTTIARDGLSSDPAVVEAAGA---- 264
Query: 250 TYGGVSGNATRPIGLRAVSAV-GNKXXXXXXXXXXXXDSADSALQFILCGAPVVQICSAV 426
GG+SG L ++ + N ++A + + GA +VQ +A
Sbjct: 265 --GGLSGAPLAARSLEVLTLIRANVPPSLCVISVGGVETAQDVQRRLDAGATLVQGYTAF 322
Query: 427 QNQDFTVVEDYITGLKAL 480
+ GL AL
Sbjct: 323 LYRGPLWARQITRGLSAL 340
>UniRef50_Q2JDS8 Cluster: Dihydroorotate dehydrogenase; n=3;
Frankia|Rep: Dihydroorotate dehydrogenase - Frankia sp.
(strain CcI3)
Length = 313
Score = 33.5 bits (73), Expect = 5.1
Identities = 35/130 (26%), Positives = 56/130 (43%), Gaps = 8/130 (6%)
Frame = +1
Query: 70 AIKIPFFVKLTP--NITDIVSIA-----VAAYEGGANGVSAINTVSGLMSVKADATPWPA 228
A ++P+ VK++P + + +V +A VAA GG V+A+NT +V D P
Sbjct: 167 ARRVPYGVKISPFSDPSALVELATVIDEVAARPGGPRFVTAVNTFPNAFAV--DDAHRPV 224
Query: 229 VGKQKRTTYGGVSGNATRPIGLRAVSAVGN-KXXXXXXXXXXXXDSADSALQFILCGAPV 405
V + G+SG A +P+GL V + ++L GA
Sbjct: 225 VDVE----LAGMSGPALKPVGLGQVRQLRRLLPESVDIIGVGGVTGGRDVADYLLAGATA 280
Query: 406 VQICSAVQNQ 435
VQ +A N+
Sbjct: 281 VQAATAFWNR 290
>UniRef50_Q9WYG8 Cluster: Dihydroorotate dehydrogenase; n=4;
Thermotogaceae|Rep: Dihydroorotate dehydrogenase -
Thermotoga maritima
Length = 270
Score = 33.5 bits (73), Expect = 5.1
Identities = 31/102 (30%), Positives = 45/102 (44%)
Frame = +1
Query: 151 GANGVSAINTVSGLMSVKADATPWPAVGKQKRTTYGGVSGNATRPIGLRAVSAVGNKXXX 330
G +G++ +NTV GL K GG+SG +PI LRAV V +
Sbjct: 172 GWDGITLVNTVRGLHFEK------------DTMILGGLSGPVLKPIALRAVYEVKKRFPE 219
Query: 331 XXXXXXXXXDSADSALQFILCGAPVVQICSAVQNQDFTVVED 456
S A +F+ GA V+ + SA+ +D VVE+
Sbjct: 220 LFVIASGGVYSVKDAEEFLKVGADVIGVGSAL-FKDPGVVEE 260
>UniRef50_A0JYE9 Cluster: Acyltransferase 3; n=1; Arthrobacter sp.
FB24|Rep: Acyltransferase 3 - Arthrobacter sp. (strain
FB24)
Length = 715
Score = 33.1 bits (72), Expect = 6.7
Identities = 19/70 (27%), Positives = 31/70 (44%)
Frame = +2
Query: 368 IRHYSSSCVVHRSYRFAVQCKIKISQWSKIT*QDLKLFCIYVLVA*TDGRDNRHLLLSTR 547
++HY S V + Y F C I + W+ T K C++VL+A H +L +
Sbjct: 151 VQHYWSLAVEEQFYIFIPLCLIAAASWATRTRVSKKQLCLFVLIA-LSAASFLHSVLFSA 209
Query: 548 KENPYKQFVT 577
++ F T
Sbjct: 210 SDHDVAYFAT 219
>UniRef50_UPI000155BFF2 Cluster: PREDICTED: hypothetical protein,
partial; n=2; Mammalia|Rep: PREDICTED: hypothetical
protein, partial - Ornithorhynchus anatinus
Length = 886
Score = 32.7 bits (71), Expect = 8.9
Identities = 26/88 (29%), Positives = 35/88 (39%)
Frame = -3
Query: 518 PVHPSRPRERRYKRALSPVM*SSTTVKS*FCTALQICTTGAPHKMNCSAESAESIPPMPS 339
P+ P+ P A P+ + + T+L TG P S ES ES P
Sbjct: 617 PLTPASPNSSPQTPARDPLAPNPPSAAISSTTSL---ATGPP-----SPESPESSSPASK 668
Query: 338 IGNPGNLFPTAETARNPIGRVAFPDTPP 255
PGN P+ T + P + P TPP
Sbjct: 669 TSTPGNSGPSNPTPQTPTSGNSTPKTPP 696
>UniRef50_Q9ULL8 Cluster: Protein Shroom4; n=17; Eutheria|Rep:
Protein Shroom4 - Homo sapiens (Human)
Length = 1498
Score = 32.7 bits (71), Expect = 8.9
Identities = 17/55 (30%), Positives = 25/55 (45%)
Frame = -3
Query: 428 CTALQICTTGAPHKMNCSAESAESIPPMPSIGNPGNLFPTAETARNPIGRVAFPD 264
C +C P +CS E + SI M S+ PG T E+ PI + +P+
Sbjct: 132 CNTSDVCVQWCPLSRHCSTEKSSSIGSMESLEQPGQ--ATYESHLLPIDQNMYPN 184
>UniRef50_Q9S2C0 Cluster: Serine/threonine-protein kinase pksC; n=2;
Streptomyces|Rep: Serine/threonine-protein kinase pksC -
Streptomyces coelicolor
Length = 556
Score = 32.7 bits (71), Expect = 8.9
Identities = 19/46 (41%), Positives = 25/46 (54%), Gaps = 2/46 (4%)
Frame = -3
Query: 332 NPGNLFPTAETARNPIGRVA--FPDTPP*VVRFCLPTAGQGVASAL 201
NP FP+AE R+ RVA F PP +V ++G GV SA+
Sbjct: 271 NPNERFPSAEAMRDECLRVAASFQAAPPSIVPGAQTSSGAGVGSAV 316
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 740,447,329
Number of Sequences: 1657284
Number of extensions: 15836103
Number of successful extensions: 44329
Number of sequences better than 10.0: 70
Number of HSP's better than 10.0 without gapping: 42331
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 44233
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 55371905986
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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