Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= brP-0388
(700 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P32929 Cluster: Cystathionine gamma-lyase; n=38; cellul... 250 2e-65
UniRef50_Q8VCN5 Cluster: Cystathionine gamma-lyase; n=39; Eukary... 235 1e-60
UniRef50_P24601 Cluster: Probable cystathionine gamma-synthase (... 222 8e-57
UniRef50_Q23CV0 Cluster: Cystathionine beta-lyase; n=3; Oligohym... 220 3e-56
UniRef50_Q97M10 Cluster: Cystathionine gamma-synthase; n=15; Bac... 218 1e-55
UniRef50_Q129P6 Cluster: Cystathionine gamma-synthase; n=11; cel... 216 4e-55
UniRef50_Q74EL7 Cluster: Cystathionine beta-lyase; n=5; Bacteria... 216 5e-55
UniRef50_Q17DR1 Cluster: Cystathionine beta-lyase; n=6; Coelomat... 216 5e-55
UniRef50_P56069 Cluster: Cystathionine gamma-synthase (EC 2.5.1.... 215 9e-55
UniRef50_Q6N7A1 Cluster: Cystathionine gamma-lyase; n=52; cellul... 210 3e-53
UniRef50_Q9EWF9 Cluster: Cystathionine gamma-synthase; n=6; Bact... 209 6e-53
UniRef50_Q5L1M8 Cluster: Cystathionine beta-lyase; n=42; Bacteri... 208 1e-52
UniRef50_Q8KEI8 Cluster: Trans-sulfuration enzyme family protein... 207 2e-52
UniRef50_Q4PK57 Cluster: Predicted cystathionine beta-lyase; n=1... 202 9e-51
UniRef50_P46807 Cluster: Cystathionine gamma-synthase (EC 2.5.1.... 202 9e-51
UniRef50_Q4A0K3 Cluster: Cystathionine gamma-synthase; n=4; Bact... 200 3e-50
UniRef50_Q838Z2 Cluster: Cystathionine beta-lyase; n=8; Bacteria... 199 5e-50
UniRef50_Q1INQ0 Cluster: Cystathionine gamma-synthase; n=2; Bact... 196 3e-49
UniRef50_Q8R9N2 Cluster: Cystathionine beta-lyases/cystathionine... 194 2e-48
UniRef50_Q5UZS6 Cluster: Cystathionine gamma-synthase; n=3; cell... 189 5e-47
UniRef50_A6LPZ9 Cluster: Cystathionine gamma-synthase; n=4; Bact... 189 7e-47
UniRef50_A7HF96 Cluster: Cystathionine gamma-synthase; n=7; Bact... 187 2e-46
UniRef50_Q2IEA5 Cluster: Cystathionine gamma-synthase; n=1; Anae... 187 3e-46
UniRef50_Q1J8Q9 Cluster: Cystathionine beta-lyase; n=14; Bacilli... 187 3e-46
UniRef50_Q9K024 Cluster: Cystathionine gamma-synthase; n=4; Neis... 185 8e-46
UniRef50_A3HJ37 Cluster: Cystathionine gamma-lyase; n=7; Gammapr... 185 1e-45
UniRef50_A6YH84 Cluster: Cystathionine gamma-synthase; n=2; Lact... 183 4e-45
UniRef50_A5E0C2 Cluster: Cystathionine gamma-lyase; n=6; cellula... 183 4e-45
UniRef50_A1ZDN6 Cluster: Cystathionine beta-lyase; n=1; Microsci... 182 7e-45
UniRef50_A0LLP6 Cluster: Cystathionine gamma-synthase; n=1; Synt... 181 1e-44
UniRef50_Q96VU8 Cluster: Cystathionine beta-lyase; n=3; Pezizomy... 181 1e-44
UniRef50_A5GJ98 Cluster: MetC/metB Cystathionine beta-lyase/cyst... 178 1e-43
UniRef50_P53780 Cluster: Cystathionine beta-lyase, chloroplast p... 177 2e-43
UniRef50_Q12L75 Cluster: Methionine gamma-lyase; n=1; Shewanella... 175 9e-43
UniRef50_Q8XNZ9 Cluster: Cystathionine gamma-synthase; n=7; Bact... 175 1e-42
UniRef50_Q49UL2 Cluster: Cystathionine beta-lyase cystathionine ... 175 1e-42
UniRef50_A1ID11 Cluster: Cystathionine gamma-synthase; n=1; Cand... 174 2e-42
UniRef50_Q5WAZ1 Cluster: Methionine gamma-lyase; n=1; Bacillus c... 173 3e-42
UniRef50_Q5MQ31 Cluster: L-methionine-gamma-lyase; n=3; Micrococ... 173 3e-42
UniRef50_Q9KEQ0 Cluster: Methionine gamma lyase; n=13; Bacillace... 173 5e-42
UniRef50_Q181I0 Cluster: Methionine gamma-lyase; n=2; Clostridiu... 172 6e-42
UniRef50_Q8TMW7 Cluster: Methionine gamma-lyase; n=3; Methanosar... 172 6e-42
UniRef50_Q1IQ68 Cluster: Cystathionine gamma-synthase; n=1; Acid... 172 8e-42
UniRef50_A1HQW4 Cluster: Cystathionine gamma-synthase; n=1; Ther... 171 1e-41
UniRef50_Q8G436 Cluster: Possible cystathionine gamma lyase; n=3... 171 1e-41
UniRef50_UPI0000E46EAD Cluster: PREDICTED: similar to methionine... 169 4e-41
UniRef50_Q67R76 Cluster: Cystathionine gamma-lyase; n=13; Bacter... 169 4e-41
UniRef50_Q1IQD6 Cluster: Cystathionine gamma-synthase; n=2; Acid... 169 7e-41
UniRef50_Q38DH3 Cluster: Cystathione gamma lyase, putative; n=7;... 169 7e-41
UniRef50_Q9KFD9 Cluster: Cystathionine gamma-synthase; n=3; Baci... 168 1e-40
UniRef50_A6GHC8 Cluster: Cystathionine gamma-synthase; n=1; Ples... 167 3e-40
UniRef50_A7H124 Cluster: Methionine gamma-lyase; n=2; Campylobac... 166 4e-40
UniRef50_Q86D27 Cluster: Methionine gamma-lyase 2; n=3; Entamoeb... 166 4e-40
UniRef50_A4EYE9 Cluster: Cystathionine beta-lyase/cystathionine ... 166 5e-40
UniRef50_A6QZA3 Cluster: Cystathionine gamma-lyase; n=1; Ajellom... 166 5e-40
UniRef50_Q9KCE4 Cluster: Cystathionine gamma-synthase (O-succiny... 165 9e-40
UniRef50_Q8R9M2 Cluster: Cystathionine beta-lyases/cystathionine... 164 2e-39
UniRef50_Q6AJ03 Cluster: Probable cystathionine beta-lyase; n=1;... 164 2e-39
UniRef50_Q0LLX7 Cluster: Cystathionine gamma-synthase; n=3; Bact... 163 3e-39
UniRef50_Q8RI67 Cluster: Cystathionine beta-lyase; n=2; Bacteria... 163 5e-39
UniRef50_O15564 Cluster: Methionine gamma-lyase; n=2; Trichomona... 162 6e-39
UniRef50_P44502 Cluster: Cystathionine gamma-synthase (EC 2.5.1.... 162 6e-39
UniRef50_Q3JCU1 Cluster: Cystathionine gamma-synthase; n=1; Nitr... 162 9e-39
UniRef50_Q8KNG3 Cluster: CalE6; n=2; Micromonosporaceae|Rep: Cal... 160 3e-38
UniRef50_Q28Q09 Cluster: Cystathionine gamma-synthase; n=7; Rhod... 160 3e-38
UniRef50_Q0B7N7 Cluster: Cystathionine gamma-synthase; n=4; Beta... 159 8e-38
UniRef50_Q2AGF7 Cluster: O-acetylhomoserine/O-acetylserine sulfh... 158 1e-37
UniRef50_Q5QWY7 Cluster: Cystathionine gamma-synthase; n=5; Prot... 157 2e-37
UniRef50_Q5GSE3 Cluster: Cystathionine beta-lyase; n=5; Wolbachi... 157 3e-37
UniRef50_A0NJV2 Cluster: O-succinylhomoserine thiol-lyase; n=2; ... 157 3e-37
UniRef50_P13254 Cluster: Methionine gamma-lyase; n=33; cellular ... 157 3e-37
UniRef50_A2BL10 Cluster: Methionine gamma-lyase; n=1; Hypertherm... 156 4e-37
UniRef50_Q5NPR0 Cluster: Cystathionine beta-lyases; n=5; Sphingo... 156 6e-37
UniRef50_Q1IQ69 Cluster: Cystathionine beta-lyase; n=6; Bacteria... 156 6e-37
UniRef50_Q97CC7 Cluster: Cystathionine beta lyase / O-succinylho... 156 6e-37
UniRef50_A4AND2 Cluster: Cystathionine gamma-lyase; n=2; cellula... 155 1e-36
UniRef50_Q1VZU8 Cluster: Cystathionine beta-lyase; n=12; Bactero... 155 1e-36
UniRef50_Q5QU17 Cluster: Methionine gamma-lyase; n=29; cellular ... 154 2e-36
UniRef50_A4FF27 Cluster: Methionine gamma-lyase; n=1; Saccharopo... 154 2e-36
UniRef50_A0LY60 Cluster: O-succinylhomoserine sulfhydrylase; n=1... 153 4e-36
UniRef50_P00935 Cluster: Cystathionine gamma-synthase (EC 2.5.1.... 153 4e-36
UniRef50_Q8G805 Cluster: Cystathionine beta-lyase; n=2; Bifidoba... 151 1e-35
UniRef50_Q399B4 Cluster: Cystathionine beta-lyase; n=15; Proteob... 151 1e-35
UniRef50_A5WG79 Cluster: O-succinylhomoserine sulfhydrylase; n=6... 151 1e-35
UniRef50_Q4QFT8 Cluster: Cystathionine beta-lyase-like protein; ... 151 1e-35
UniRef50_A6PIC3 Cluster: Cystathionine beta-lyase; n=1; Shewanel... 150 3e-35
UniRef50_Q49UL3 Cluster: Cystathionine beta-lyase cystathionine ... 150 4e-35
UniRef50_Q1GNK9 Cluster: Cystathionine beta-lyase; n=4; Sphingom... 150 4e-35
UniRef50_A6W1L9 Cluster: Cystathionine gamma-synthase; n=10; Bac... 150 4e-35
UniRef50_A1ZIW0 Cluster: Cys/Met metabolism pyridoxal-phosphate-... 150 4e-35
UniRef50_A1A0Q5 Cluster: Cystathionine beta-lyase; n=2; Bifidoba... 150 4e-35
UniRef50_Q0ALD7 Cluster: Cystathionine gamma-synthase; n=2; Hyph... 149 5e-35
UniRef50_Q5PBE9 Cluster: Cystathionine beta-lyase; n=1; Anaplasm... 149 9e-35
UniRef50_Q338K0 Cluster: Cys/Met metabolism PLP-dependent enzyme... 149 9e-35
UniRef50_Q11FS5 Cluster: Cystathionine beta-lyase; n=5; Alphapro... 148 1e-34
UniRef50_A7DB98 Cluster: Cystathionine gamma-synthase; n=2; Meth... 148 1e-34
UniRef50_A4AA77 Cluster: Cystathionine beta-lyase; n=2; Bacteria... 147 2e-34
UniRef50_Q1ELY9 Cluster: Cystathionine beta-lyases/cystathionine... 147 3e-34
UniRef50_P55217 Cluster: Cystathionine gamma-synthase, chloropla... 147 3e-34
UniRef50_A3VS82 Cluster: Cystathionine gamma-synthase; n=1; Parv... 146 5e-34
UniRef50_A6X770 Cluster: Cystathionine gamma-synthase; n=1; Ochr... 146 6e-34
UniRef50_Q1AT24 Cluster: Cystathionine gamma-synthase; n=2; Bact... 145 8e-34
UniRef50_Q9V088 Cluster: MetB cystathionine gamma-synthase (EC 4... 145 8e-34
UniRef50_P55218 Cluster: O-succinylhomoserine sulfhydrylase; n=9... 145 8e-34
UniRef50_Q493X0 Cluster: Beta-cystathionase; n=2; Enterobacteria... 144 1e-33
UniRef50_Q89VE2 Cluster: O-succinylhomoserine sulfhydrylase; n=7... 144 2e-33
UniRef50_Q1GQF1 Cluster: Cystathionine beta-lyase; n=1; Sphingop... 144 2e-33
UniRef50_A6UGP2 Cluster: Cystathionine gamma-synthase; n=1; Sino... 144 2e-33
UniRef50_O94350 Cluster: Cystathionine beta-lyase; n=27; cellula... 143 3e-33
UniRef50_Q46V95 Cluster: Cystathionine beta-lyase, bacterial; n=... 143 4e-33
UniRef50_A5CVL3 Cluster: O-succinylhomoserine sulfhydrylase; n=3... 143 4e-33
UniRef50_Q67QQ8 Cluster: Cystathionine gamma-lyase; n=1; Symbiob... 142 6e-33
UniRef50_Q1IZN0 Cluster: Cystathionine gamma-synthase; n=1; Dein... 142 7e-33
UniRef50_A1SSS1 Cluster: Cystathionine beta-lyase; n=10; Gammapr... 142 7e-33
UniRef50_Q8RI68 Cluster: Cystathionine gamma-synthase; n=1; Fuso... 140 2e-32
UniRef50_Q7X137 Cluster: Cystathionine gamma lyase-like protein;... 140 2e-32
UniRef50_Q5FUW3 Cluster: Cystathionine beta-lyase; n=3; Acetobac... 140 3e-32
UniRef50_Q6W1U5 Cluster: Cystathionine gamma-synthase; n=2; Prot... 140 3e-32
UniRef50_A0JSU6 Cluster: Cys/Met metabolism pyridoxal-phosphate-... 140 3e-32
UniRef50_Q2S2T9 Cluster: Cystathionine beta-lyase MetC; n=1; Sal... 140 4e-32
UniRef50_Q97PS4 Cluster: Transulfuration enzyme family protein; ... 139 5e-32
UniRef50_A5V1Q1 Cluster: Cystathionine gamma-synthase; n=2; Rose... 139 5e-32
UniRef50_A0VE37 Cluster: Cystathionine beta-lyase; n=2; Comamona... 139 5e-32
UniRef50_A6LZ85 Cluster: O-acetylhomoserine aminocarboxypropyltr... 113 8e-32
UniRef50_Q62JZ5 Cluster: Cystathionine beta-lyase; n=37; Burkhol... 138 9e-32
UniRef50_A3UCA9 Cluster: Cystathionine gamma-synthase; n=2; Hyph... 138 9e-32
UniRef50_Q97W69 Cluster: O-succinylhomoserine (Thiol)-lyase; n=5... 138 1e-31
UniRef50_Q7UQA0 Cluster: Cystathionine gamma-synthase; n=4; Bact... 138 2e-31
UniRef50_Q0APK0 Cluster: Cystathionine beta-lyase; n=1; Maricaul... 138 2e-31
UniRef50_Q98K64 Cluster: Methionine gamma-lyase; n=13; Bacteria|... 137 2e-31
UniRef50_A5EU95 Cluster: Cystathionine beta-lyase; n=1; Bradyrhi... 137 2e-31
UniRef50_O02215 Cluster: Putative uncharacterized protein; n=3; ... 137 3e-31
UniRef50_Q52811 Cluster: Putative cystathionine beta-lyase; n=35... 137 3e-31
UniRef50_O69592 Cluster: O-succinylhomoserine sulfhydrylase; n=1... 136 4e-31
UniRef50_Q6L1U0 Cluster: Cystathionine beta-lyase; n=1; Picrophi... 136 4e-31
UniRef50_Q5K6Y9 Cluster: Cystathionine gamma-lyase, putative; n=... 136 5e-31
UniRef50_Q07703 Cluster: Cystathionine beta-lyase; n=6; Burkhold... 136 5e-31
UniRef50_Q47S97 Cluster: Cystathionine gamma-synthase; n=1; Ther... 135 9e-31
UniRef50_A6W2A4 Cluster: Cystathionine beta-lyase; n=1; Marinomo... 135 9e-31
UniRef50_A0L907 Cluster: Cystathionine gamma-synthase; n=1; Magn... 135 9e-31
UniRef50_A3JID5 Cluster: Cystathionine beta-lyase; n=3; Marinoba... 134 1e-30
UniRef50_Q1ITX7 Cluster: Cystathionine gamma-lyase; n=1; Acidoba... 133 5e-30
UniRef50_Q98LV9 Cluster: Methionine gamma lyase; n=4; Rhizobiale... 132 6e-30
UniRef50_A0JSB0 Cluster: O-acetylhomoserine/O-acetylserine sulfh... 113 8e-30
UniRef50_Q11C77 Cluster: Cystathionine beta-lyase; n=1; Mesorhiz... 132 1e-29
UniRef50_Q0C2A8 Cluster: Cystathionine beta-lyase; n=1; Hyphomon... 131 2e-29
UniRef50_Q7W586 Cluster: Cystathionine beta-lyase; n=3; Bordetel... 130 2e-29
UniRef50_P53101 Cluster: Cystathionine beta-lyase; n=5; Saccharo... 130 2e-29
UniRef50_P44527 Cluster: Cystathionine beta-lyase; n=78; Gammapr... 130 2e-29
UniRef50_Q9X0Z7 Cluster: Cystathionine gamma-synthase; n=2; Ther... 130 3e-29
UniRef50_Q01X62 Cluster: Cystathionine gamma-synthase; n=1; Soli... 130 3e-29
UniRef50_A6GRN0 Cluster: Cystathionine beta-lyase; n=1; Limnobac... 130 3e-29
UniRef50_UPI00015BB00D Cluster: cystathionine gamma-synthase; n=... 130 4e-29
UniRef50_Q13Z52 Cluster: Cystathionine beta-lyase; n=2; Burkhold... 130 4e-29
UniRef50_A7H1V2 Cluster: Cystathionine beta-lyase; n=15; Campylo... 130 4e-29
UniRef50_Q5LWC9 Cluster: Cys/Met metabolism PLP-dependent enzyme... 129 7e-29
UniRef50_Q11MH2 Cluster: Cys/Met metabolism pyridoxal-phosphate-... 129 7e-29
UniRef50_A0H5P3 Cluster: Cys/Met metabolism pyridoxal-phosphate-... 129 7e-29
UniRef50_UPI000155C3C4 Cluster: PREDICTED: similar to cystathion... 128 1e-28
UniRef50_Q82YZ5 Cluster: Cystathionine gamma-synthase, putative;... 128 1e-28
UniRef50_Q2JBH0 Cluster: O-succinylhomoserine sulfhydrylase; n=1... 128 1e-28
UniRef50_A4CKV8 Cluster: Cystathionine beta-lyase; n=11; Bactero... 128 1e-28
UniRef50_Q7X1G1 Cluster: Lfe147p1; n=2; Leptospirillum|Rep: Lfe1... 127 3e-28
UniRef50_P43623 Cluster: Putative cystathionine beta-lyase; n=11... 126 4e-28
UniRef50_A3X9V5 Cluster: Cystathionine gamma-synthase; n=12; Rho... 126 5e-28
UniRef50_A5G088 Cluster: Cystathionine gamma-synthase; n=1; Acid... 124 2e-27
UniRef50_A3U7R8 Cluster: O-acetylhomoserine sulfhydrylase; n=8; ... 124 2e-27
UniRef50_Q9RSD8 Cluster: O-acetylhomoserine (Thiol)-lyase/O-acet... 124 2e-27
UniRef50_Q26GX1 Cluster: Cys/Met metabolism PLP-dependent enzyme... 123 4e-27
UniRef50_A5G8H3 Cluster: O-acetylhomoserine aminocarboxypropyltr... 123 5e-27
UniRef50_Q89V23 Cluster: O-acetylhomoserine sulfhydrylase; n=13;... 121 1e-26
UniRef50_Q5NQQ3 Cluster: Cystathionine beta-lyase; n=41; Proteob... 121 1e-26
UniRef50_Q1V2M7 Cluster: Cystathionine beta-lyase; n=2; Candidat... 121 1e-26
UniRef50_Q8NM00 Cluster: Cystathionine beta-lyases/cystathionine... 121 2e-26
UniRef50_Q2K0N3 Cluster: Cystathionine gamma-synthase protein; n... 121 2e-26
UniRef50_Q4AEY8 Cluster: Cystathionine gamma-synthase; n=1; Chlo... 121 2e-26
UniRef50_Q98KA4 Cluster: Probable cystathionine/methionine gamma... 120 3e-26
UniRef50_Q67VG6 Cluster: Putative O-succinylhomoserine (Thiol)-l... 119 8e-26
UniRef50_Q7M844 Cluster: O-ACETYLHOMOSERINE (THIOL)-LYASE; n=1; ... 93 1e-25
UniRef50_Q1GVW8 Cluster: Cystathionine gamma-lyase; n=15; Bacter... 118 1e-25
UniRef50_Q7WM51 Cluster: Cystathionase beta-lyase; n=3; Proteoba... 118 2e-25
UniRef50_Q8FRS9 Cluster: O-acetylhomoserine sulfhydrylase; n=8; ... 91 2e-25
UniRef50_A3UCF8 Cluster: Cystathionine beta-lyase; n=1; Oceanica... 116 4e-25
UniRef50_UPI0000F2BB70 Cluster: PREDICTED: similar to Chain A, C... 116 7e-25
UniRef50_A7HB44 Cluster: Cys/Met metabolism pyridoxal-phosphate-... 116 7e-25
UniRef50_Q59829 Cluster: Putative cystathionine gamma-lyase; n=8... 116 7e-25
UniRef50_UPI0000E47CE2 Cluster: PREDICTED: similar to cystathion... 115 1e-24
UniRef50_Q97MT9 Cluster: O-acetylhomoserine sulfhydrylase; n=4; ... 115 1e-24
UniRef50_A3VUE2 Cluster: Cystathionine beta-lyase; n=1; Parvular... 115 1e-24
UniRef50_Q4Q511 Cluster: Cystathionine beta-lyase, putative; n=3... 115 1e-24
UniRef50_A5KK19 Cluster: Putative uncharacterized protein; n=1; ... 114 2e-24
UniRef50_A5ZYG7 Cluster: Putative uncharacterized protein; n=1; ... 114 2e-24
UniRef50_A5MZA3 Cluster: O-acetyl-L-homoserine sulfhydrylase-rel... 114 2e-24
UniRef50_A1I7W3 Cluster: O-acetylhomoserine aminocarboxypropyltr... 114 2e-24
UniRef50_A3SR24 Cluster: Cystathionine gamma-synthase; n=3; Alph... 113 3e-24
UniRef50_Q979X4 Cluster: Cystathionine beta lyase / O-succinylho... 113 3e-24
UniRef50_Q8EM13 Cluster: O-acetylhomoserine sulfhydrylase; n=86;... 113 4e-24
UniRef50_Q0B5H9 Cluster: Cys/Met metabolism pyridoxal-phosphate-... 113 5e-24
UniRef50_Q6MN74 Cluster: Cys/Met metabolism lyase; n=1; Bdellovi... 112 7e-24
UniRef50_Q7WKX4 Cluster: Cys/Met metabolism PLP-dependent enzyme... 111 2e-23
UniRef50_Q65SV6 Cluster: Putative uncharacterized protein; n=1; ... 111 2e-23
UniRef50_A6NZI8 Cluster: Putative uncharacterized protein; n=1; ... 110 4e-23
UniRef50_Q89XR2 Cluster: O-acetylhomoserine sulfhydrylase; n=24;... 109 5e-23
UniRef50_Q9SGU9 Cluster: F1N19.23; n=7; Magnoliophyta|Rep: F1N19... 109 5e-23
UniRef50_UPI0000E0F9F5 Cluster: hypothetical protein OM2255_2257... 109 6e-23
UniRef50_Q9YA71 Cluster: Cystathionine gamma-synthase; n=1; Aero... 109 8e-23
UniRef50_A0JYV8 Cluster: Cystathionine gamma-synthase; n=8; Acti... 108 1e-22
UniRef50_Q62BJ4 Cluster: Trans-sulfuration enzyme family protein... 107 2e-22
UniRef50_A7CL93 Cluster: Cys/Met metabolism pyridoxal-phosphate-... 107 2e-22
UniRef50_A4S3Y0 Cluster: Putative 2nd cystathione gamma synthase... 107 3e-22
UniRef50_A5MZ94 Cluster: O-acetyl-L-homoserine sulfhydrylase-rel... 107 3e-22
UniRef50_A5WGJ5 Cluster: O-acetylhomoserine/O-acetylserine sulfh... 106 5e-22
UniRef50_Q76K51 Cluster: O-acetyl-L-homoserine sulfhydrylase; n=... 104 2e-21
UniRef50_A6GJL1 Cluster: Methionine gamma-lyase; n=1; Plesiocyst... 104 2e-21
UniRef50_A2Z703 Cluster: Putative uncharacterized protein; n=3; ... 104 2e-21
UniRef50_Q7VIG9 Cluster: O-acetylhomoserine (Thiol)-lyase MetY; ... 104 2e-21
UniRef50_Q0SFV6 Cluster: O-acetylhomoserine aminocarboxypropyltr... 104 2e-21
UniRef50_Q7M9C8 Cluster: O-ACETYLHOMOSERINE SULFHYDRYLASE; n=1; ... 103 3e-21
UniRef50_A3K0Q5 Cluster: O-succinylhomoserine sulfhydrylase; n=3... 103 3e-21
UniRef50_A1W861 Cluster: Cys/Met metabolism pyridoxal-phosphate-... 103 6e-21
UniRef50_Q67KY0 Cluster: O-acetylhomoserine sulfhydrylase; n=28;... 102 7e-21
UniRef50_UPI0000E4882F Cluster: PREDICTED: hypothetical protein,... 102 1e-20
UniRef50_Q1DAY0 Cluster: Cys/Met metabolism PLP-dependent enzyme... 102 1e-20
UniRef50_A2Y9X5 Cluster: Putative uncharacterized protein; n=1; ... 99 1e-20
UniRef50_Q5LN68 Cluster: Cys/Met metabolism PLP-dependent enzyme... 101 2e-20
UniRef50_Q895W3 Cluster: O-acetylhomoserine sulfhydrylase; n=40;... 99 5e-20
UniRef50_A1TP30 Cluster: Cys/Met metabolism pyridoxal-phosphate-... 100 7e-20
UniRef50_Q31RB7 Cluster: O-acetylhomoserine/O-acetylserine sulfh... 99 9e-20
UniRef50_O42851 Cluster: Uncharacterized trans-sulfuration enzym... 99 9e-20
UniRef50_A3PXR9 Cluster: Cys/Met metabolism pyridoxal-phosphate-... 98 2e-19
UniRef50_Q1NS60 Cluster: O-acetylhomoserine aminocarboxypropyltr... 98 2e-19
UniRef50_P06106 Cluster: Protein MET17 [Includes: O-acetylhomose... 97 4e-19
UniRef50_A5CMC2 Cluster: O-acetylhomoserine (Thiol)-lyase; n=2; ... 97 5e-19
UniRef50_Q6F7Q9 Cluster: Putative cystathionine beta-lyase, PLP-... 95 1e-18
UniRef50_Q5UZ20 Cluster: O-acetylhomoserine (Thiol)-lyase; n=10;... 95 1e-18
UniRef50_A0V4A3 Cluster: O-acetylhomoserine/O-acetylserine sulfh... 95 2e-18
UniRef50_A1SMU4 Cluster: O-acetylhomoserine/O-acetylserine sulfh... 94 3e-18
UniRef50_Q00ZR7 Cluster: Cystathionine gamma-synthase; n=1; Ostr... 94 3e-18
UniRef50_Q756K4 Cluster: AER250Cp; n=6; Saccharomycetales|Rep: A... 94 3e-18
UniRef50_A6Q4H8 Cluster: O-acetylhomoserine sulfhydrylase; n=3; ... 91 2e-17
UniRef50_P38716 Cluster: Uncharacterized trans-sulfuration enzym... 91 2e-17
UniRef50_Q28LE3 Cluster: Cys/Met metabolism pyridoxal-phosphate-... 91 3e-17
UniRef50_A7INF9 Cluster: O-acetylhomoserine aminocarboxypropyltr... 91 3e-17
UniRef50_A7S3X8 Cluster: Predicted protein; n=1; Nematostella ve... 90 4e-17
UniRef50_A1CUZ3 Cluster: Homocysteine synthase, putative; n=1; N... 90 6e-17
UniRef50_Q8J0B2 Cluster: Homocysteine synthase-like protein; n=2... 87 5e-16
UniRef50_A1D936 Cluster: Cystathionine gamma-synthase; n=21; Asc... 86 9e-16
UniRef50_A7DHV1 Cluster: O-acetylhomoserine aminocarboxypropyltr... 85 2e-15
UniRef50_Q64XN5 Cluster: O-acetylhomoserine sulfhydrylase; n=3; ... 84 4e-15
UniRef50_A5BR77 Cluster: Putative uncharacterized protein; n=1; ... 84 4e-15
UniRef50_Q3IV09 Cluster: O-acetylhomoserine sulfhydrylase; n=1; ... 82 1e-14
UniRef50_Q7P3Q8 Cluster: Methionine gamma-lyase; n=1; Fusobacter... 82 1e-14
UniRef50_Q45278 Cluster: Aminotransferase and dihydrorhizobitoxi... 82 1e-14
UniRef50_A5W0L6 Cluster: Cys/Met metabolism pyridoxal-phosphate-... 82 1e-14
UniRef50_Q4WFS7 Cluster: Cystathionine beta-lyase; n=2; Pezizomy... 81 2e-14
UniRef50_Q3A8R5 Cluster: O-acetylhomoserine/O-acetylserine sulfh... 81 3e-14
UniRef50_Q1QM61 Cluster: Cys/Met metabolism pyridoxal-phosphate-... 58 1e-13
UniRef50_Q0V7G5 Cluster: Putative uncharacterized protein; n=1; ... 77 6e-13
UniRef50_A2BPN5 Cluster: Possible Cystathionine gamma-synthase; ... 71 2e-11
UniRef50_Q2UI88 Cluster: Cystathionine beta-lyases/cystathionine... 70 5e-11
UniRef50_Q3AI46 Cluster: Possible cystathionine gamma-synthase; ... 68 3e-10
UniRef50_A1DJG8 Cluster: Cystathionine gamma-synthase; n=1; Neos... 64 2e-09
UniRef50_Q6N7A9 Cluster: Putative homocysteine synthase; n=1; Rh... 62 1e-08
UniRef50_A7TA32 Cluster: Predicted protein; n=1; Nematostella ve... 60 7e-08
UniRef50_Q6C8S4 Cluster: Similar to tr|Q86ZL4 Podospora anserina... 60 7e-08
UniRef50_Q2UJR0 Cluster: Cystathionine beta-lyases/cystathionine... 60 7e-08
UniRef50_A7CR38 Cluster: Cys/Met metabolism pyridoxal-phosphate-... 59 9e-08
UniRef50_P38675 Cluster: Cystathionine gamma-synthase (EC 2.5.1.... 56 6e-07
UniRef50_Q54RW8 Cluster: Putative uncharacterized protein; n=1; ... 56 8e-07
UniRef50_A3JA39 Cluster: O-acetylhomoserine/O-acetylserine sulfh... 54 3e-06
UniRef50_Q12198 Cluster: Putative cystathionine gamma-synthase Y... 54 3e-06
UniRef50_Q2C9J3 Cluster: Cystathionine beta-lyase; n=1; Photobac... 53 8e-06
UniRef50_A4AZ61 Cluster: Homocysteine synthase; n=7; Gammaproteo... 52 1e-05
UniRef50_P47164 Cluster: Cystathionine gamma-synthase (EC 2.5.1.... 52 1e-05
UniRef50_Q6FK75 Cluster: Similar to sp|P47164 Saccharomyces cere... 52 1e-05
UniRef50_O74314 Cluster: Probable cystathionine gamma-synthase (... 52 1e-05
UniRef50_A7TG47 Cluster: Putative uncharacterized protein; n=1; ... 51 3e-05
UniRef50_Q2HHZ6 Cluster: Putative uncharacterized protein; n=1; ... 50 5e-05
UniRef50_A6R1N2 Cluster: Cystathionine gamma-synthase; n=1; Ajel... 50 5e-05
UniRef50_A3LX62 Cluster: Predicted protein; n=6; Saccharomycetal... 50 5e-05
UniRef50_Q8F9S7 Cluster: Cystathionine gamma-synthase; n=4; Lept... 49 1e-04
UniRef50_Q98EJ5 Cluster: Aspartate aminotransferase; n=3; cellul... 48 2e-04
UniRef50_Q6CWG2 Cluster: Similar to sp|P47164 Saccharomyces cere... 48 2e-04
UniRef50_Q2H8C4 Cluster: Putative uncharacterized protein; n=1; ... 48 2e-04
UniRef50_Q2U598 Cluster: Cystathionine beta-lyases/cystathionine... 47 4e-04
UniRef50_UPI000023F0A1 Cluster: hypothetical protein FG08909.1; ... 46 7e-04
UniRef50_Q5KL05 Cluster: Cystathionine gamma-synthase, putative;... 46 7e-04
UniRef50_Q7SD09 Cluster: Putative uncharacterized protein NCU081... 46 9e-04
UniRef50_Q83WD5 Cluster: Putative cystathionine/methionine gamma... 45 0.002
UniRef50_A4XL24 Cluster: Aminotransferase, class I and II; n=1; ... 43 0.006
UniRef50_Q2NFU9 Cluster: UPF0425 pyridoxal phosphate-dependent p... 43 0.008
UniRef50_Q58097 Cluster: Probable aspartate aminotransferase 2; ... 43 0.008
UniRef50_A6C1Z0 Cluster: Selenocysteine lyase; n=1; Planctomyces... 42 0.011
UniRef50_A7DS52 Cluster: Aminotransferase, class I and II; n=1; ... 42 0.011
UniRef50_Q8RA65 Cluster: Cystathionine beta-lyases/cystathionine... 42 0.019
UniRef50_Q8A2D0 Cluster: Aspartate aminotransferase; n=1; Bacter... 42 0.019
UniRef50_Q2HFC3 Cluster: Putative uncharacterized protein; n=1; ... 42 0.019
UniRef50_A4R0S4 Cluster: Putative uncharacterized protein; n=1; ... 41 0.025
UniRef50_Q58365 Cluster: Histidinol-phosphate aminotransferase; ... 41 0.025
UniRef50_Q26GZ8 Cluster: Aminotransferase class I /II; n=4; Bact... 41 0.034
UniRef50_A7MW66 Cluster: Putative uncharacterized protein; n=3; ... 41 0.034
UniRef50_Q1VY21 Cluster: Coproporphyrinogen III oxidase; n=1; Ps... 40 0.044
UniRef50_Q1IU09 Cluster: Putative uncharacterized protein; n=1; ... 40 0.044
UniRef50_Q5X017 Cluster: Putative uncharacterized protein; n=1; ... 40 0.059
UniRef50_A5HZP1 Cluster: Glycine cleavage system P protein; n=4;... 40 0.059
UniRef50_A7NVA1 Cluster: Chromosome chr18 scaffold_1, whole geno... 40 0.059
UniRef50_Q8R6L3 Cluster: Selenocysteine lyase; n=7; Clostridia|R... 40 0.078
UniRef50_Q1E2P4 Cluster: Putative uncharacterized protein; n=1; ... 40 0.078
UniRef50_A4QZ48 Cluster: Putative uncharacterized protein; n=1; ... 40 0.078
UniRef50_Q2AE33 Cluster: Glycine cleavage system P-protein; n=1;... 39 0.10
UniRef50_O14209 Cluster: Uncharacterized aminotransferase C6B12.... 39 0.10
UniRef50_Q60317 Cluster: Probable aspartate aminotransferase 1; ... 39 0.10
UniRef50_Q4P760 Cluster: Putative uncharacterized protein; n=1; ... 39 0.14
UniRef50_Q2U6Q0 Cluster: Cystathionine beta-lyases/cystathionine... 39 0.14
UniRef50_UPI000023F307 Cluster: hypothetical protein FG00503.1; ... 38 0.18
UniRef50_A1SNC2 Cluster: Cysteine desulfurase family protein; n=... 38 0.18
UniRef50_Q9Y9P0 Cluster: Aspartate aminotransferase; n=3; Thermo... 38 0.24
UniRef50_Q8Y5X8 Cluster: Histidinol-phosphate aminotransferase; ... 38 0.24
UniRef50_Q8NMH4 Cluster: PLP-dependent aminotransferases; n=5; C... 38 0.31
UniRef50_A6LSW9 Cluster: Putative L-threonine-O-3-phosphate deca... 38 0.31
UniRef50_Q0RYX5 Cluster: Glycine dehydrogenase (Decarboxylating)... 37 0.41
UniRef50_A7GCC1 Cluster: Dipeptidase; n=11; Bacteria|Rep: Dipept... 37 0.41
UniRef50_A4IWT8 Cluster: Aminotransferase, class I/II; n=12; Fra... 37 0.41
UniRef50_A7TP63 Cluster: Putative uncharacterized protein; n=1; ... 37 0.41
UniRef50_UPI00015B5B66 Cluster: PREDICTED: similar to kynurenine... 37 0.55
UniRef50_Q3VR79 Cluster: Aminotransferase, class I and II; n=6; ... 37 0.55
UniRef50_A4B3S6 Cluster: Probable aspartate aminotransferase; n=... 37 0.55
UniRef50_Q6BZ38 Cluster: Debaryomyces hansenii chromosome A of s... 37 0.55
UniRef50_A7D358 Cluster: Aminotransferase, class I and II; n=1; ... 37 0.55
UniRef50_Q8R5Q4 Cluster: Histidinol-phosphate aminotransferase; ... 37 0.55
UniRef50_Q9K5N2 Cluster: Aminotransferase required for NAD biosy... 36 0.72
UniRef50_Q8PUG6 Cluster: Aspartate aminotransferase; n=8; Archae... 36 0.72
UniRef50_Q98AR6 Cluster: Aspartate transaminase; n=2; Mesorhizob... 36 0.96
UniRef50_Q8YGW6 Cluster: CYSTEINE DESULFHYDRASE / SELENOCYSTEINE... 36 0.96
UniRef50_Q186L1 Cluster: Aminomethyltransferase; n=20; Firmicute... 36 0.96
UniRef50_A5UT24 Cluster: Aminotransferase, class V; n=4; Chlorof... 36 0.96
UniRef50_Q3T4B9 Cluster: NADH-ubiquinone oxidoreductase chain 4;... 36 0.96
UniRef50_Q88UE6 Cluster: Histidinol-phosphate aminotransferase; ... 36 0.96
UniRef50_Q97I22 Cluster: Cystathionine beta-lyase family protein... 36 1.3
UniRef50_Q2J5M7 Cluster: Glycine dehydrogenase; n=8; Bacteria|Re... 36 1.3
UniRef50_Q2BCQ0 Cluster: Putative uncharacterized protein; n=1; ... 36 1.3
UniRef50_Q2NEQ0 Cluster: HisC; n=2; Methanobacteriaceae|Rep: His... 36 1.3
UniRef50_Q18SB5 Cluster: Cysteine desulfurase family protein; n=... 35 1.7
UniRef50_Q0AY85 Cluster: Putative aluminum resistance protein; n... 35 1.7
UniRef50_Q0AVP5 Cluster: Selenocysteine lyase; n=2; Clostridiale... 35 1.7
UniRef50_A4A5L3 Cluster: Aspartate aminotransferase; n=1; Congre... 35 1.7
UniRef50_O51111 Cluster: Probable cysteine desulfurase; n=3; Bor... 35 1.7
UniRef50_Q895G6 Cluster: Aspartate aminotransferase; n=21; Bacte... 35 2.2
UniRef50_Q1IMV6 Cluster: Aminotransferase, class I and II; n=3; ... 35 2.2
UniRef50_A6TKT2 Cluster: Histidinol-phosphate aminotransferase; ... 35 2.2
UniRef50_Q7RBN5 Cluster: Arabidopsis thaliana T27G7.17, putative... 35 2.2
UniRef50_P45051 Cluster: Oligopeptide transport ATP-binding prot... 35 2.2
UniRef50_UPI00006CC2B8 Cluster: aminotransferase, classes I and ... 34 2.9
UniRef50_Q97CZ3 Cluster: Uncharacterized conserved membrane prot... 34 2.9
UniRef50_Q6KIL1 Cluster: Aminotransferase protein S homolog; n=1... 34 2.9
UniRef50_A5ZAJ8 Cluster: Putative uncharacterized protein; n=1; ... 34 2.9
UniRef50_A4LHD4 Cluster: Isopenicillin N epimerase; n=13; Burkho... 34 2.9
UniRef50_A4E9G5 Cluster: Putative uncharacterized protein; n=1; ... 34 2.9
UniRef50_Q8H0S1 Cluster: At1g28060/F13K9_16; n=6; Magnoliophyta|... 34 2.9
UniRef50_UPI00015BC868 Cluster: UPI00015BC868 related cluster; n... 33 5.1
UniRef50_Q8YQG4 Cluster: Alr3867 protein; n=3; Bacteria|Rep: Alr... 33 5.1
UniRef50_Q7NDX4 Cluster: Glr4108 protein; n=17; cellular organis... 33 5.1
UniRef50_A3DJF2 Cluster: Histidinol-phosphate aminotransferase; ... 33 5.1
UniRef50_Q979X6 Cluster: Amino acid aminotransferase; n=5; Therm... 33 5.1
UniRef50_Q26HA0 Cluster: Putative uncharacterized protein; n=1; ... 33 6.7
UniRef50_Q18Y53 Cluster: Aminotransferase, class I and II; n=11;... 33 6.7
UniRef50_A6M305 Cluster: Putative ribonuclease BN; n=1; Clostrid... 33 6.7
UniRef50_Q5CUF9 Cluster: Conserved COOH terminal-specific cystei... 33 6.7
UniRef50_A7UG05 Cluster: Orf2 protein; n=1; Phaeosphaeria nodoru... 33 6.7
UniRef50_Q6C7U7 Cluster: Putative methyltransferase UPF0383; n=1... 33 6.7
UniRef50_Q6ABU3 Cluster: Putative phenylalanine aminotransferase... 33 6.7
UniRef50_UPI000150AA2B Cluster: aminotransferase, classes I and ... 33 8.9
UniRef50_Q7CGF4 Cluster: Aspartate aminotransferase; n=9; Bacter... 33 8.9
UniRef50_Q1IPF6 Cluster: Aminotransferase, class I and II; n=6; ... 33 8.9
UniRef50_Q1F0R0 Cluster: Histidinol-phosphate aminotransferase; ... 33 8.9
UniRef50_Q18C70 Cluster: Putative histidinol-phosphate aminotran... 33 8.9
UniRef50_Q11IA0 Cluster: Aminotransferase, class I and II; n=2; ... 33 8.9
UniRef50_Q039A8 Cluster: Histidinol-phosphate/aromatic aminotran... 33 8.9
UniRef50_A7HJK1 Cluster: Aminotransferase class I and II; n=1; F... 33 8.9
UniRef50_A6M3L7 Cluster: Cysteine desulfurase family protein; n=... 33 8.9
UniRef50_A5FNG3 Cluster: Aminotransferase, class I and II precur... 33 8.9
UniRef50_Q6FP34 Cluster: Candida glabrata strain CBS138 chromoso... 33 8.9
UniRef50_Q4P4X1 Cluster: Putative uncharacterized protein; n=1; ... 33 8.9
UniRef50_Q2UPN4 Cluster: Aspartate/tyrosine/aromatic aminotransf... 33 8.9
UniRef50_Q5KXV3 Cluster: Histidinol-phosphate aminotransferase; ... 33 8.9
UniRef50_Q5X5X0 Cluster: Histidinol-phosphate aminotransferase 1... 33 8.9
UniRef50_Q9HPJ9 Cluster: Probable glycine dehydrogenase [decarbo... 33 8.9
>UniRef50_P32929 Cluster: Cystathionine gamma-lyase; n=38; cellular
organisms|Rep: Cystathionine gamma-lyase - Homo sapiens
(Human)
Length = 405
Score = 250 bits (612), Expect = 2e-65
Identities = 113/211 (53%), Positives = 149/211 (70%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
T T+ LL GD I+ DDVYGGTNR RQV S G+ +F D + I+ ++ A+ TK+
Sbjct: 94 TVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETKL 153
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
+WIETPTNP KV+DIE I GDII+VVDNTF++PY Q+PL GADI MYS TKY
Sbjct: 154 VWIETPTNPTQKVIDIEGCAHIVHKHGDIILVVDNTFMSPYFQRPLALGADISMYSATKY 213
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
MNGHSDV+MG VN +++ ++LRFLQN++G VPSPIDCY NR LKTL +RME H K+
Sbjct: 214 MNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNG 273
Query: 543 LIIANWLEKHPKIVEVLHPXLXTHPHTXXLK 635
+ +A +LE +P + +V++P L +HP +K
Sbjct: 274 MAVAQFLESNPWVEKVIYPGLPSHPQHELVK 304
>UniRef50_Q8VCN5 Cluster: Cystathionine gamma-lyase; n=39;
Eukaryota|Rep: Cystathionine gamma-lyase - Mus musculus
(Mouse)
Length = 398
Score = 235 bits (574), Expect = 1e-60
Identities = 106/205 (51%), Positives = 142/205 (69%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
T T+ LL GD I+ D+VYGGTNR R+V S G+ +F D + + ++ A+ TK+
Sbjct: 93 TITITHLLKAGDEIICMDEVYGGTNRYFRRVASEFGLKISFVDCSKTKLLEAAITPQTKL 152
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
+WIETPTNP LK+ DI A +I RGDII+VVDNTF++ Y Q+PL GADI M S TKY
Sbjct: 153 VWIETPTNPTLKLADIGACAQIVHKRGDIILVVDNTFMSAYFQRPLALGADICMCSATKY 212
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
MNGHSDV+MG VN + +LRFLQN++G VPSP DCY R LKTL +RME H K+
Sbjct: 213 MNGHSDVVMGLVSVNSDDLNSRLRFLQNSLGAVPSPFDCYLCCRGLKTLQVRMEKHFKNG 272
Query: 543 LIIANWLEKHPKIVEVLHPXLXTHP 617
+ +A +LE +P++ +V++P L +HP
Sbjct: 273 MAVARFLETNPRVEKVVYPGLPSHP 297
>UniRef50_P24601 Cluster: Probable cystathionine gamma-synthase (EC
2.5.1.48) (CGS) (O- succinylhomoserine (thiol)-lyase);
n=52; cellular organisms|Rep: Probable cystathionine
gamma-synthase (EC 2.5.1.48) (CGS) (O-
succinylhomoserine (thiol)-lyase) - Herpetosiphon
aurantiacus (Herpetosiphon giganteus)
Length = 319
Score = 222 bits (542), Expect = 8e-57
Identities = 98/205 (47%), Positives = 149/205 (72%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
+TTL+ +L GDH++ DDVYGGT RL ++V++ G++ F D + E V+ A++ NT++
Sbjct: 80 STTLMLMLKAGDHVICGDDVYGGTYRLFQRVMTEHGLSFDFIDMADPEAVRAAIKPNTRL 139
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
IW+ETPTNPLLK+ I AI ++AR G I +VDNTF +PY Q+P+ GAD+V++S TKY
Sbjct: 140 IWLETPTNPLLKLAPIAAITRVAREHG-IWTIVDNTFASPYNQRPITLGADMVLHSTTKY 198
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
+ GHSDV+ GA + ++ + +KL+FLQNA G VP P DC+ V R +KTL++RM ++++
Sbjct: 199 IGGHSDVVGGAIMTSNDELYEKLKFLQNAAGAVPGPFDCWLVLRGVKTLSIRMRDDERNA 258
Query: 543 LIIANWLEKHPKIVEVLHPXLXTHP 617
L IA +L +HP + +V++P L +HP
Sbjct: 259 LAIAQFLTEHPGVEKVIYPGLPSHP 283
>UniRef50_Q23CV0 Cluster: Cystathionine beta-lyase; n=3;
Oligohymenophorea|Rep: Cystathionine beta-lyase -
Tetrahymena thermophila SB210
Length = 409
Score = 220 bits (537), Expect = 3e-56
Identities = 104/206 (50%), Positives = 139/206 (67%), Gaps = 2/206 (0%)
Frame = +3
Query: 6 TTLVALLNHGDHIVSSDDVYGGTNRLLRQ-VVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
T ++ L HI+ SDDVYGGTNR +R+ V + N F D T+ E KNA +ENT +
Sbjct: 100 TCVLHSLPKESHIIVSDDVYGGTNRYMRRFAVEKFNFNVEFVDLTDTEAFKNAFKENTAL 159
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRG-DIIVVVDNTFLTPYLQKPLDFGADIVMYSLTK 359
+WIETPTNPL+K+VDIEA+V I R + D V+VDNTF +PYLQ P+D G DI ++S++K
Sbjct: 160 VWIETPTNPLIKLVDIEALVNITREKKKDTWVLVDNTFASPYLQNPMDLGVDITLHSVSK 219
Query: 360 YMNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKS 539
Y+ GHSDVIMGA + N K + DKL + + G PS DCY R LKTL RM+ H ++
Sbjct: 220 YIGGHSDVIMGALVFNGKEMKDKLFYSSISFGGCPSTFDCYLAVRGLKTLESRMKIHCRN 279
Query: 540 SLIIANWLEKHPKIVEVLHPXLXTHP 617
+ +A WLE+HP I +V+ P L +HP
Sbjct: 280 AYSVAKWLEQHPLIEKVIFPGLESHP 305
>UniRef50_Q97M10 Cluster: Cystathionine gamma-synthase; n=15;
Bacteria|Rep: Cystathionine gamma-synthase - Clostridium
acetobutylicum
Length = 384
Score = 218 bits (532), Expect = 1e-55
Identities = 94/211 (44%), Positives = 151/211 (71%)
Frame = +3
Query: 6 TTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMI 185
++++ + GDHI+ SDD+YGGT R+ ++ GI T+TD T+ E ++ ++ENTK I
Sbjct: 85 SSVLTIFKGGDHIIVSDDLYGGTYRIFEEIYEHYGIEVTYTDTTSTENIEKELRENTKAI 144
Query: 186 WIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYM 365
++ETPTNPL+K+ DI + K+A+ +++V DNTF+TPY QKPL+ GADIV++S TKY+
Sbjct: 145 YLETPTNPLMKITDIREVSKLAKEHNTLLIV-DNTFMTPYYQKPLELGADIVLHSGTKYL 203
Query: 366 NGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSL 545
GH+D + G I+ND+ + +KLRF+QN++G V +P D + + R +KTL +R++ +++++
Sbjct: 204 CGHNDALAGFVILNDERLIEKLRFIQNSVGAVLAPFDSWLILRGIKTLHIRLDRQQENAI 263
Query: 546 IIANWLEKHPKIVEVLHPXLXTHPHTXXLKN 638
IAN+L+KH KI +VL+P L H LK+
Sbjct: 264 KIANFLKKHKKITKVLYPGLEEHVGHDILKS 294
>UniRef50_Q129P6 Cluster: Cystathionine gamma-synthase; n=11;
cellular organisms|Rep: Cystathionine gamma-synthase -
Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 381
Score = 216 bits (528), Expect = 4e-55
Identities = 97/205 (47%), Positives = 145/205 (70%)
Frame = +3
Query: 6 TTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMI 185
+T++ L+ GDH+V D+YGGT RL+ +V +R GI +F D T+ ++ A++ T+++
Sbjct: 79 STVLQSLSSGDHVVCGQDLYGGTYRLMTKVFARFGIEASFVDATSPGAIRAALRPQTRLV 138
Query: 186 WIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYM 365
W+ETP+NPLL V DI AI ++A + VDNTF +PYLQ+PL GADIV++S TKY+
Sbjct: 139 WLETPSNPLLTVCDIAAIAQLAHEH-QARLAVDNTFASPYLQQPLRLGADIVIHSTTKYL 197
Query: 366 NGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSL 545
GHSDVI GA ++ND+A+ +L+FLQNA+G VP P+DC+ V R +KTLA+RM H ++L
Sbjct: 198 GGHSDVIGGALVMNDEALYQELKFLQNAVGAVPGPLDCFLVLRGIKTLAVRMRQHCDNAL 257
Query: 546 IIANWLEKHPKIVEVLHPXLXTHPH 620
+A L HP++ ++ +P L + PH
Sbjct: 258 QLARHLAAHPEVKQLAYPGLESSPH 282
>UniRef50_Q74EL7 Cluster: Cystathionine beta-lyase; n=5;
Bacteria|Rep: Cystathionine beta-lyase - Geobacter
sulfurreducens
Length = 378
Score = 216 bits (527), Expect = 5e-55
Identities = 96/204 (47%), Positives = 142/204 (69%)
Frame = +3
Query: 6 TTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMI 185
++ + L + GDH+V +DVYGGT R L Q+ SRLG+ +TF D T+ ++ A + NTK +
Sbjct: 79 SSTLLLFSPGDHLVVCEDVYGGTFRALTQLFSRLGVESTFVDATDTAAIEAAFRPNTKGL 138
Query: 186 WIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYM 365
++ETP+NPL+K+ D+ A ++AR RG I +VDNTF+TPYLQ+PLD G D+V++S TK++
Sbjct: 139 YLETPSNPLMKITDLAAAARLARERG-AITLVDNTFMTPYLQRPLDLGCDVVLHSGTKFL 197
Query: 366 NGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSL 545
NGHSDV+ G A+V D +G ++RF+QNA G + P D + V R +KTL +RME + ++
Sbjct: 198 NGHSDVVCGFAVVRDPELGQRIRFIQNAFGAILGPQDSWLVLRGIKTLRVRMEESQAGAV 257
Query: 546 IIANWLEKHPKIVEVLHPXLXTHP 617
IANWL ++ V +P L HP
Sbjct: 258 KIANWLAGEKRVSRVFYPGLPDHP 281
>UniRef50_Q17DR1 Cluster: Cystathionine beta-lyase; n=6;
Coelomata|Rep: Cystathionine beta-lyase - Aedes aegypti
(Yellowfever mosquito)
Length = 438
Score = 216 bits (527), Expect = 5e-55
Identities = 116/240 (48%), Positives = 153/240 (63%), Gaps = 35/240 (14%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
TTT++ +L+ GDHIV+ DD+YGGTNRLLR+V ++ I F D T++ KV+ A++ NTK+
Sbjct: 100 TTTVITMLSAGDHIVAGDDLYGGTNRLLRKVAMKMNIEVDFVDCTDLAKVEAAVKPNTKL 159
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGA---------- 332
WIETPTNPLLKV+DIEA+ ++A ++VVVDNTFL+ YLQ+PLD GA
Sbjct: 160 FWIETPTNPLLKVIDIEAVSEVAHKFPGVVVVVDNTFLSAYLQRPLDLGADIVMYSLTKY 219
Query: 333 -----DIVM----------YSLTKYM-NGH--------SDVIMGAAIVNDKAIGDKLRFL 440
D++M Y K++ NG S +++ I D + + +L
Sbjct: 220 MNGHSDVIMGAAIMNDEALYEQLKFLQNGKLLLTTLLLSHIVVNDCICKDTRVSRFMHYL 279
Query: 441 Q-NAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLIIANWLEKHPKIVEVLHPXLXTHP 617
A GIVPSP DCY VNRSLKTLALRME HK +SL IA +LEKHPK+ VLHP L +HP
Sbjct: 280 SPTAAGIVPSPFDCYLVNRSLKTLALRMERHKSNSLAIAKFLEKHPKVERVLHPGLPSHP 339
Score = 33.1 bits (72), Expect = 6.7
Identities = 13/26 (50%), Positives = 17/26 (65%)
Frame = +2
Query: 620 HXIXKKXMTGHSGVFSFKXSGGLKES 697
H + KK GHSG+ SF GG++ES
Sbjct: 341 HELAKKQTYGHSGIMSFYIKGGMEES 366
>UniRef50_P56069 Cluster: Cystathionine gamma-synthase (EC 2.5.1.48)
(CGS) (O-succinylhomoserine (thiol)-lyase); n=24;
Bacteria|Rep: Cystathionine gamma-synthase (EC 2.5.1.48)
(CGS) (O-succinylhomoserine (thiol)-lyase) -
Helicobacter pylori (Campylobacter pylori)
Length = 380
Score = 215 bits (525), Expect = 9e-55
Identities = 96/201 (47%), Positives = 140/201 (69%)
Frame = +3
Query: 18 ALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWIET 197
+LL GDH++ DDVYGGT RL QV+ + G++ T D ++I ++K A++ NTK +++ET
Sbjct: 83 SLLQSGDHVLLGDDVYGGTFRLFNQVLVKNGLSCTIIDTSDISQIKKAIKPNTKALYLET 142
Query: 198 PTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNGHS 377
P+NPLLK+ D+ +A+ G ++ +VDNTF TPY Q PL GADIV +S TKY+ GHS
Sbjct: 143 PSNPLLKITDLAQCASVAKDHG-LLTIVDNTFATPYYQNPLLLGADIVAHSGTKYLGGHS 201
Query: 378 DVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLIIAN 557
DV+ G N++A+ ++ F QNA+G V P D + + R +KTL LRME H+K++L +A
Sbjct: 202 DVVAGLVTTNNEALAQEIAFFQNAIGGVLGPQDSWLLQRGIKTLGLRMEAHQKNALCVAE 261
Query: 558 WLEKHPKIVEVLHPXLXTHPH 620
+LEKHPK+ V +P L THP+
Sbjct: 262 FLEKHPKVERVYYPGLPTHPN 282
>UniRef50_Q6N7A1 Cluster: Cystathionine gamma-lyase; n=52; cellular
organisms|Rep: Cystathionine gamma-lyase -
Rhodopseudomonas palustris
Length = 390
Score = 210 bits (512), Expect = 3e-53
Identities = 95/203 (46%), Positives = 139/203 (68%), Gaps = 1/203 (0%)
Frame = +3
Query: 12 LVALLNHGDHIVSSDDVYGGTNRLLRQVVSR-LGINTTFTDFTNIEKVKNAMQENTKMIW 188
L+ + G HIV+SDD+YGG+ RL +V S G+ T D N++ +++A+Q NT IW
Sbjct: 90 LLEIAGQGSHIVASDDLYGGSWRLFHRVRSHSAGLTITHVDPANLDALRDAIQPNTAFIW 149
Query: 189 IETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMN 368
IETP+NP L++ D+EAI I R RG ++ VVDNTF +P +Q+PL+ G DIV++S+TKY+
Sbjct: 150 IETPSNPTLRLADLEAIAAIGRERG-VLTVVDNTFASPAVQRPLEHGIDIVVHSVTKYIG 208
Query: 369 GHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLI 548
GHSD++ GA +V D + KL+FLQNA G + P + R +KTL LR++ H ++L
Sbjct: 209 GHSDIVGGAIVVRDPDLAQKLQFLQNATGGILDPFSSFLALRGIKTLPLRVQRHSSNALA 268
Query: 549 IANWLEKHPKIVEVLHPXLXTHP 617
+A WL+ HPKI V++P L +HP
Sbjct: 269 VARWLDAHPKIERVVYPGLNSHP 291
>UniRef50_Q9EWF9 Cluster: Cystathionine gamma-synthase; n=6;
Bacteria|Rep: Cystathionine gamma-synthase -
Streptomyces coelicolor
Length = 386
Score = 209 bits (510), Expect = 6e-53
Identities = 97/202 (48%), Positives = 136/202 (67%)
Frame = +3
Query: 12 LVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWI 191
L LL GDH+V +D YGGT RL +V +R G+ + D ++ V+ A+ TK +W+
Sbjct: 92 LRTLLRPGDHVVIPNDAYGGTFRLFAKVATRWGVEWSVADTSDAAAVRAALTPKTKAVWV 151
Query: 192 ETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNG 371
ETP+NPLL + DI + ++AR G +VV DNTF TPYLQ+PL GAD+V++SLTKYM G
Sbjct: 152 ETPSNPLLGITDIAQVAQVARDAGARLVV-DNTFATPYLQQPLALGADVVVHSLTKYMGG 210
Query: 372 HSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLII 551
HSDV+ GA IV D+ +G++L F QNAMG V P D + V R KTLA+RM+ H +++ +
Sbjct: 211 HSDVVGGALIVGDQELGEELAFHQNAMGAVAGPFDSWLVLRGTKTLAVRMDRHSENATKV 270
Query: 552 ANWLEKHPKIVEVLHPXLXTHP 617
A+ L +H ++ VL+P L HP
Sbjct: 271 ADMLSRHARVTSVLYPGLPEHP 292
>UniRef50_Q5L1M8 Cluster: Cystathionine beta-lyase; n=42;
Bacteria|Rep: Cystathionine beta-lyase - Geobacillus
kaustophilus
Length = 393
Score = 208 bits (507), Expect = 1e-52
Identities = 95/204 (46%), Positives = 142/204 (69%)
Frame = +3
Query: 6 TTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMI 185
+T LL+ GDH++ ++DVYGGT R++ +V+ R GI TF D T++ V ++ NTK+I
Sbjct: 83 STAFLLLSKGDHVLVTEDVYGGTYRMITEVLGRFGIEYTFVDMTDLNAVAENIRPNTKVI 142
Query: 186 WIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYM 365
++ETP+NPLLKV DI+ +VK+A++ G + +DNTF+TP LQ+PLD G D+V++S TK++
Sbjct: 143 YMETPSNPLLKVTDIQGVVKLAKAHG-CLTFLDNTFMTPALQRPLDLGVDVVLHSATKFL 201
Query: 366 NGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSL 545
GHSDV+ G A+V D+ +G +L LQNA G V D + V R LKTL +R++ +S+
Sbjct: 202 AGHSDVVAGLAVVKDEELGKELYKLQNAFGAVLGVQDAWLVLRGLKTLHVRLKQSSESAA 261
Query: 546 IIANWLEKHPKIVEVLHPXLXTHP 617
IA +L HPK+ +V +P L HP
Sbjct: 262 AIAKYLACHPKVEKVYYPGLENHP 285
>UniRef50_Q8KEI8 Cluster: Trans-sulfuration enzyme family protein;
n=8; Chlorobiaceae|Rep: Trans-sulfuration enzyme family
protein - Chlorobium tepidum
Length = 380
Score = 207 bits (505), Expect = 2e-52
Identities = 93/199 (46%), Positives = 136/199 (68%)
Frame = +3
Query: 21 LLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWIETP 200
+L GDH+VSS DVYGG+ R+ Q++ G+ T++ E ++ T+MIWIE+P
Sbjct: 84 VLKPGDHVVSSLDVYGGSYRIFEQLMRPWGVETSYAASEATESYIECIRPETRMIWIESP 143
Query: 201 TNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNGHSD 380
+NPLL++ DI A+ +IA RG I++ VDNTF +PY Q+PLD GA IV++S TKY+ GHSD
Sbjct: 144 SNPLLQICDIRALAEIANERG-IVLAVDNTFASPYFQRPLDLGAHIVVHSTTKYLGGHSD 202
Query: 381 VIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLIIANW 560
VI GA + +D + +R Q A G +P P DC+ ++R +KTL +RME H+K++L +A
Sbjct: 203 VIGGAVVASDDNLNLTIRNYQGAAGAIPGPWDCWLISRGIKTLKIRMEEHQKNALHLARA 262
Query: 561 LEKHPKIVEVLHPXLXTHP 617
LEKHP + V++P L +HP
Sbjct: 263 LEKHPAVSRVIYPGLESHP 281
>UniRef50_Q4PK57 Cluster: Predicted cystathionine beta-lyase; n=1;
uncultured bacterium MedeBAC49C08|Rep: Predicted
cystathionine beta-lyase - uncultured bacterium
MedeBAC49C08
Length = 262
Score = 202 bits (492), Expect = 9e-51
Identities = 96/205 (46%), Positives = 142/205 (69%), Gaps = 3/205 (1%)
Frame = +3
Query: 12 LVALLNHGDHIVSSDDVYGGTNRLLRQVVS-RLGINTTFTDFTNIEKVKNAMQENTKMIW 188
+++LL GDHI++ DD+YGGT RL ++ S GI ++ D + + ++ +++ NTKM++
Sbjct: 13 VLSLLQPGDHIIAMDDLYGGTVRLFNEIKSISQGIEISYVDMSKEKNIEASIKPNTKMLF 72
Query: 189 IETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMN 368
ETPTNPLLK++D+E + ARS+ +II V DNTF +PY+Q+PL G D V++S TKY+
Sbjct: 73 AETPTNPLLKIIDLEKLADFARSK-NIITVADNTFCSPYIQRPLTKGFDYVIHSATKYLC 131
Query: 369 GHSDVIMGAAIVNDKAIGDKLRF--LQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
GHSDVIMG ++ D + R + N++G + SP D Y RSLKTLALRME H ++
Sbjct: 132 GHSDVIMGVLVMKDAESDNSKRISNIHNSLGPISSPFDSYLALRSLKTLALRMERHSSNA 191
Query: 543 LIIANWLEKHPKIVEVLHPXLXTHP 617
IA++LE HPKI +V++P L +HP
Sbjct: 192 EKIADFLESHPKISKVIYPGLESHP 216
>UniRef50_P46807 Cluster: Cystathionine gamma-synthase (EC 2.5.1.48)
(CGS) (O-succinylhomoserine (thiol)-lyase); n=42;
cellular organisms|Rep: Cystathionine gamma-synthase (EC
2.5.1.48) (CGS) (O-succinylhomoserine (thiol)-lyase) -
Mycobacterium leprae
Length = 388
Score = 202 bits (492), Expect = 9e-51
Identities = 90/202 (44%), Positives = 135/202 (66%)
Frame = +3
Query: 12 LVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWI 191
L +L GDH++ DDVYGGT RL+ +V ++ ++ T ++++ V+ A+ T++IW+
Sbjct: 94 LRVMLRPGDHVIIPDDVYGGTFRLIDKVFTQWNVDYTPVPLSDLDAVRAAITSRTRLIWV 153
Query: 192 ETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNG 371
ETPTNPLL + DI +I ++ + + V+VDNTF +P LQ+PL GAD+V++S TKY+ G
Sbjct: 154 ETPTNPLLSIADITSIGELGKKHS-VKVLVDNTFASPALQQPLMLGADVVLHSTTKYIGG 212
Query: 372 HSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLII 551
HSDV+ GA + ND+ + FLQN G VPSP D Y R LKTL LRM+ H ++++ +
Sbjct: 213 HSDVVGGALVTNDEELDQAFGFLQNGAGAVPSPFDAYLTMRGLKTLVLRMQRHNENAITV 272
Query: 552 ANWLEKHPKIVEVLHPXLXTHP 617
A +L HP + VL+P L +HP
Sbjct: 273 AEFLAGHPSVSAVLYPGLPSHP 294
>UniRef50_Q4A0K3 Cluster: Cystathionine gamma-synthase; n=4;
Bacteria|Rep: Cystathionine gamma-synthase -
Staphylococcus saprophyticus subsp. saprophyticus
(strain ATCC 15305 /DSM 20229)
Length = 381
Score = 200 bits (488), Expect = 3e-50
Identities = 93/203 (45%), Positives = 137/203 (67%)
Frame = +3
Query: 6 TTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMI 185
+ ++ LL+ GDH++ + DVYGGT R L +V +R GI+ F D TNIE V+ ++ TKM+
Sbjct: 80 SAVIMLLDKGDHLLINSDVYGGTYRALTKVFNRFGIDAEFIDTTNIEAVEQYIKPETKML 139
Query: 186 WIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYM 365
+IETP+NPLL+V DI+ +IA+ +I VVDNTF+TPY Q PL G DIV++S TKY+
Sbjct: 140 YIETPSNPLLRVTDIKKSAEIAKKH-HLISVVDNTFMTPYFQNPLTLGIDIVLHSATKYI 198
Query: 366 NGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSL 545
GHSDV+ G +D + ++L F+QN+ G V P D Y + R +KTL LRME ++++L
Sbjct: 199 GGHSDVVAGLVATSDAELAERLGFIQNSTGGVLGPQDSYLLIRGIKTLGLRMEQVQRNTL 258
Query: 546 IIANWLEKHPKIVEVLHPXLXTH 614
I + L++H + +V HP + H
Sbjct: 259 AIIDMLQQHSAVKQVFHPSISDH 281
>UniRef50_Q838Z2 Cluster: Cystathionine beta-lyase; n=8;
Bacteria|Rep: Cystathionine beta-lyase - Enterococcus
faecalis (Streptococcus faecalis)
Length = 378
Score = 199 bits (486), Expect = 5e-50
Identities = 92/202 (45%), Positives = 136/202 (67%)
Frame = +3
Query: 12 LVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWI 191
++++ DHI+ DDVYGG+ RLL +V G++ T + +++ ++ A+Q NTK +++
Sbjct: 81 IISMFGPEDHILLGDDVYGGSFRLLDKVFVANGLSYTIVNASDLSTIEAAIQPNTKALFL 140
Query: 192 ETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNG 371
ETP+NPLLK+ DIEA K+A+ ++ +VDNTF TPY Q+PL GADIV++S TKY+ G
Sbjct: 141 ETPSNPLLKITDIEAAAKLAKKH-QLLTIVDNTFATPYFQRPLALGADIVVHSGTKYLGG 199
Query: 372 HSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLII 551
HSDV+ G + N +K+ FLQNA+G V P D + V RSLKTL +RM H +++ I
Sbjct: 200 HSDVVSGLVVTNHPESAEKIAFLQNAIGAVLGPHDSWLVQRSLKTLGVRMAAHAQNAQKI 259
Query: 552 ANWLEKHPKIVEVLHPXLXTHP 617
A +LE HP + V +P L +HP
Sbjct: 260 AEFLEAHPAVATVYYPGLASHP 281
>UniRef50_Q1INQ0 Cluster: Cystathionine gamma-synthase; n=2;
Bacteria|Rep: Cystathionine gamma-synthase -
Acidobacteria bacterium (strain Ellin345)
Length = 385
Score = 196 bits (479), Expect = 3e-49
Identities = 89/204 (43%), Positives = 139/204 (68%)
Frame = +3
Query: 6 TTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMI 185
+ + +LL GDH+V S +VYGG RL QV+ G+ T+ D ++++ + A++ +TK +
Sbjct: 85 SAMCSLLKKGDHVVCSSNVYGGVPRLFNQVLVNYGLEFTYVDTSDLKATEKAIRRSTKYV 144
Query: 186 WIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYM 365
+IETPTNPL+ + DIEAI +IA +G VVVDNTF++PY QKP+ GAD+V++S TK++
Sbjct: 145 YIETPTNPLMVLSDIEAISQIAHKKGTE-VVVDNTFMSPYFQKPIALGADMVLHSTTKFL 203
Query: 366 NGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSL 545
NGHSD + G + K +KL F+Q ++G + SP + + + R +KTLA+RM+ H +S
Sbjct: 204 NGHSDGLGGVLVCTTKEQSEKLAFIQKSVGAIMSPFESWLILRGVKTLAVRMKQHDESGR 263
Query: 546 IIANWLEKHPKIVEVLHPXLXTHP 617
++A++L K KI +V +P L HP
Sbjct: 264 VVADFLAKQKKIKKVFYPGLPDHP 287
>UniRef50_Q8R9N2 Cluster: Cystathionine beta-lyases/cystathionine
gamma-synthases; n=4; Bacteria|Rep: Cystathionine
beta-lyases/cystathionine gamma-synthases -
Thermoanaerobacter tengcongensis
Length = 393
Score = 194 bits (473), Expect = 2e-48
Identities = 95/205 (46%), Positives = 138/205 (67%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
++ L+A +N GDHI+++ D+YGGTN L RLGI + DF+++E V+ A++ NTK+
Sbjct: 91 SSALLAEVNSGDHIIAAKDIYGGTNSLFNLEFKRLGIEISLVDFSDLESVEKAIKPNTKV 150
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
I++E TNPL++V DIE +VKIA+ G + ++VDNTF TPYL +PL+ GA V++S TKY
Sbjct: 151 IYMEIMTNPLIRVFDIEEVVKIAKRHG-LKLIVDNTFTTPYLIRPLEVGAYAVIHSATKY 209
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
+NGHSDVI G N + I R + N G + SP D + R KTL LRM H K++
Sbjct: 210 INGHSDVIGGLIAGNKEFIFRTRRIVHNFGGSM-SPFDAWLTLRGAKTLFLRMREHCKNA 268
Query: 543 LIIANWLEKHPKIVEVLHPXLXTHP 617
+ +A +LE HPK+ +V +P L +HP
Sbjct: 269 MRLAEFLESHPKVKKVFYPGLPSHP 293
>UniRef50_Q5UZS6 Cluster: Cystathionine gamma-synthase; n=3;
cellular organisms|Rep: Cystathionine gamma-synthase -
Haloarcula marismortui (Halobacterium marismortui)
Length = 411
Score = 189 bits (461), Expect = 5e-47
Identities = 85/206 (41%), Positives = 136/206 (66%), Gaps = 2/206 (0%)
Frame = +3
Query: 6 TTLVALLNHGDHIVSSDDVYGGTNRLLRQVV-SRLGINTTFTDFTNIEKVKNAMQENTKM 182
T +++L+ GDH+V+ DD+Y GT R+ + +LG++ F D T+ + V AM T++
Sbjct: 106 TAVLSLVEPGDHVVAFDDLYAGTRRMFETLFRDQLGVDVEFVDATDADAVAAAMTPATEL 165
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
+W+ETPTNP +K+ DI+AI +A D V VDNTF +PY Q+PL GAD+V++S TKY
Sbjct: 166 VWVETPTNPRIKLCDIDAIAAVAADY-DATVGVDNTFASPYFQQPLSLGADLVVHSTTKY 224
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQN-AMGIVPSPIDCYFVNRSLKTLALRMEHHKKS 539
+NGHSD + GA I +D + +++ F Q A+G + +P D Y ++R +KTL +RM H+ +
Sbjct: 225 LNGHSDAVGGALITDDPEVAERVEFRQQIALGNMLAPFDSYLISRGIKTLGVRMTRHENN 284
Query: 540 SLIIANWLEKHPKIVEVLHPXLXTHP 617
++ +A +L+ H + V +P L +HP
Sbjct: 285 AMALAQYLDDHEHVETVHYPGLESHP 310
>UniRef50_A6LPZ9 Cluster: Cystathionine gamma-synthase; n=4;
Bacteria|Rep: Cystathionine gamma-synthase - Clostridium
beijerinckii NCIMB 8052
Length = 382
Score = 189 bits (460), Expect = 7e-47
Identities = 86/200 (43%), Positives = 136/200 (68%)
Frame = +3
Query: 6 TTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMI 185
T + L GDHI+ SDD+YGGT RL + G+ TF D T + + N+++ENTK I
Sbjct: 83 TACIHLFKSGDHIILSDDLYGGTYRLFDDIFRDFGLEATFVDTTITKNILNSIKENTKAI 142
Query: 186 WIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYM 365
IETP+NP++KV DI+A+ +I ++ ++++VDNTFLTPY Q+PL+ GAD+V++S TK++
Sbjct: 143 LIETPSNPMMKVTDIKAVAEITKAN-KLLLIVDNTFLTPYYQRPLELGADLVVHSGTKFL 201
Query: 366 NGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSL 545
GH D++ G + ND+ I +KLR + + G SP D + + R +KTL +R+E ++++L
Sbjct: 202 GGHHDLLAGFIVANDEEILEKLRRIHMSTGATLSPFDSWLILRGIKTLHIRLERSQENTL 261
Query: 546 IIANWLEKHPKIVEVLHPXL 605
IA +LE +PK+ +V + L
Sbjct: 262 KIAKFLEGNPKVEKVYYVGL 281
>UniRef50_A7HF96 Cluster: Cystathionine gamma-synthase; n=7;
Bacteria|Rep: Cystathionine gamma-synthase -
Anaeromyxobacter sp. Fw109-5
Length = 426
Score = 187 bits (456), Expect = 2e-46
Identities = 86/201 (42%), Positives = 130/201 (64%), Gaps = 2/201 (0%)
Frame = +3
Query: 21 LLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWIETP 200
LL HG H++ + D YGGT R L + G+ T+ D +++ V A + NT+M+WIETP
Sbjct: 125 LLPHGSHLLCTVDCYGGTFRALEHAKAAYGLEVTYLDLADLDSVAAAFRPNTRMVWIETP 184
Query: 201 TNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNGHSD 380
+NPLL++ D+ A+ +AR R D + VVDNTFL+P Q+P GA++V++S TKY+NGHSD
Sbjct: 185 SNPLLRLTDVAAVAALAR-RHDALTVVDNTFLSPASQQPFRHGAELVVHSTTKYLNGHSD 243
Query: 381 VIMGAAIV--NDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLIIA 554
V+ GA + A+ +++ + N +G SP DC+ V R LKTL LRM H+ + +A
Sbjct: 244 VVGGAVVAAPGRSALVQRIQSVNNLLGTSQSPHDCFLVLRGLKTLLLRMRAHEAGARAVA 303
Query: 555 NWLEKHPKIVEVLHPXLXTHP 617
++L HP + +V +P L +HP
Sbjct: 304 DFLAAHPAVAKVHYPGLASHP 324
>UniRef50_Q2IEA5 Cluster: Cystathionine gamma-synthase; n=1;
Anaeromyxobacter dehalogenans 2CP-C|Rep: Cystathionine
gamma-synthase - Anaeromyxobacter dehalogenans (strain
2CP-C)
Length = 426
Score = 187 bits (455), Expect = 3e-46
Identities = 88/201 (43%), Positives = 133/201 (66%), Gaps = 2/201 (0%)
Frame = +3
Query: 21 LLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWIETP 200
LL HG H++ + D YGGT R L G+ T+ D ++ V+ A++ NT M+WIETP
Sbjct: 125 LLPHGSHLLCTVDCYGGTFRTLEHARQAYGLEVTYLDLADLGAVERALRPNTGMVWIETP 184
Query: 201 TNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNGHSD 380
+NPLL++ DI A+ ++A RG +VVVDNTFL+P LQ+P + GAD+V++S TKY+NGHSD
Sbjct: 185 SNPLLRLTDIRAVTELAHRRG-ALVVVDNTFLSPALQRPFEHGADLVVHSTTKYLNGHSD 243
Query: 381 VIMGAAIV-NDK-AIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLIIA 554
V+ GA + D+ A+ +++ + N +G P D + V R LKTLALR++ H+ + +A
Sbjct: 244 VVGGAVVAPRDRTALLQRIQSMNNLLGTSQGPHDAFLVLRGLKTLALRVKAHEAGARRVA 303
Query: 555 NWLEKHPKIVEVLHPXLXTHP 617
+L HP++ V +P L +HP
Sbjct: 304 AFLAGHPEVARVHYPGLASHP 324
>UniRef50_Q1J8Q9 Cluster: Cystathionine beta-lyase; n=14;
Bacilli|Rep: Cystathionine beta-lyase - Streptococcus
pyogenes serotype M4 (strain MGAS10750)
Length = 463
Score = 187 bits (455), Expect = 3e-46
Identities = 84/205 (40%), Positives = 139/205 (67%)
Frame = +3
Query: 6 TTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMI 185
+T++ LL GDH++ +VYGGT + ++ I T+F D ++ VK +++ NT+MI
Sbjct: 164 STVLMLLKAGDHVIFPLEVYGGTCQFATAILPNYQIETSFVDMADLATVKASIRPNTRMI 223
Query: 186 WIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYM 365
++ETP+NPLLK+ DI +V++A++ G ++ V DNTF+T Q+PL G DIV+ S+TK++
Sbjct: 224 YLETPSNPLLKICDISELVQLAKAYG-VLTVADNTFMTSLYQEPLAMGVDIVVESVTKFI 282
Query: 366 NGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSL 545
NGHSDV+ G A N++AI ++L+ Q G + D + + R +KT+ +RME K++
Sbjct: 283 NGHSDVVAGLAATNNEAIYNQLKLFQKNFGAIVGVEDAWLILRGMKTMGIRMEQAVKNAQ 342
Query: 546 IIANWLEKHPKIVEVLHPXLXTHPH 620
+AN+L KHPK+++V +P L +HP+
Sbjct: 343 QLANYLAKHPKVLKVHYPGLDSHPN 367
>UniRef50_Q9K024 Cluster: Cystathionine gamma-synthase; n=4;
Neisseria|Rep: Cystathionine gamma-synthase - Neisseria
meningitidis serogroup B
Length = 385
Score = 185 bits (451), Expect = 8e-46
Identities = 89/200 (44%), Positives = 125/200 (62%), Gaps = 1/200 (0%)
Frame = +3
Query: 24 LNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQEN-TKMIWIETP 200
L GD IV+ D+YGG LL V + G+N F D N + + ++ + K++W+ETP
Sbjct: 86 LRPGDTIVAVADIYGGAYDLLVDVYQKWGVNVVFADLGNPDNLDELLKAHKVKLVWLETP 145
Query: 201 TNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNGHSD 380
+NPLL++VDI+ + A++ G +V +DNTF TPYLQ+PLD G D V +S TKY+ GHSD
Sbjct: 146 SNPLLRLVDIKVLAAKAKAAG-ALVGIDNTFATPYLQQPLDMGCDFVFHSATKYLCGHSD 204
Query: 381 VIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLIIANW 560
V+MG + K + L + G V P+DC+ V R +KTLALRM H +++L IA
Sbjct: 205 VLMGIVVAKTKELAQPLHDMMVHTGAVAGPLDCWLVLRGIKTLALRMNAHCQNALEIARR 264
Query: 561 LEKHPKIVEVLHPXLXTHPH 620
LE HP I +V HP L +H H
Sbjct: 265 LEAHPAIEKVFHPGLPSHEH 284
>UniRef50_A3HJ37 Cluster: Cystathionine gamma-lyase; n=7;
Gammaproteobacteria|Rep: Cystathionine gamma-lyase -
Pseudomonas putida (strain GB-1)
Length = 400
Score = 185 bits (450), Expect = 1e-45
Identities = 87/206 (42%), Positives = 135/206 (65%), Gaps = 1/206 (0%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRL-GINTTFTDFTNIEKVKNAMQENTK 179
T T++ LL H+V + VYGGT R++ SR G+ TT+ D ++E V A++ T+
Sbjct: 94 TATVLELLPKDAHVVVMNGVYGGTFRIMEDYRSRTSGLTTTYVDLNDLEAVAAAIKPQTQ 153
Query: 180 MIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTK 359
+IWIE+PTNPLL +VDI+A+ +A++RG I+ +DNTF +P+ Q+P+ G D+VM+S +K
Sbjct: 154 LIWIESPTNPLLHLVDIKAVCDLAKARG-ILTCIDNTFCSPWNQRPITLGVDLVMHSASK 212
Query: 360 YMNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKS 539
Y+ GHSD+ G + + A+ +LR + A+G V P DCY R LKTL +RME +
Sbjct: 213 YIGGHSDLTGGVVVAANDALLARLRRISMAIGAVQGPFDCYLALRGLKTLDVRMERQCAN 272
Query: 540 SLIIANWLEKHPKIVEVLHPXLXTHP 617
+L +A +LE H ++ +V +P L +HP
Sbjct: 273 ALQVARFLESHAQVEQVYYPGLESHP 298
>UniRef50_A6YH84 Cluster: Cystathionine gamma-synthase; n=2;
Lactobacillus casei|Rep: Cystathionine gamma-synthase -
Lactobacillus casei
Length = 378
Score = 183 bits (445), Expect = 4e-45
Identities = 84/203 (41%), Positives = 132/203 (65%)
Frame = +3
Query: 9 TLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIW 188
T++A+ G H + D +Y GT+RLL Q ++ G+ T D ++ V+ A++ TK I+
Sbjct: 81 TVLAIFPDGSHFIIGDSLYSGTDRLLNQYFAQHGLTFTPVDPRDLTAVEAAIRPETKAIF 140
Query: 189 IETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMN 368
ET +NPLLKV ++AI +A++ D++ +VDNTFLTPY Q+PLD GADIV++S TKY+
Sbjct: 141 FETFSNPLLKVSSVKAISTLAKAH-DLLTIVDNTFLTPYYQRPLDLGADIVLHSATKYIG 199
Query: 369 GHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLI 548
GH D+I G + I +K+ FLQN +G + +P+DC V R + TLA+R++ ++
Sbjct: 200 GHGDLIAGLVVSASPEISEKIGFLQNTIGAILAPLDCSLVCRGIATLAVRLDRETSNAQA 259
Query: 549 IANWLEKHPKIVEVLHPXLXTHP 617
+A +LE+HP + V +P L + P
Sbjct: 260 VAEFLEQHPDVAHVYYPGLKSDP 282
>UniRef50_A5E0C2 Cluster: Cystathionine gamma-lyase; n=6; cellular
organisms|Rep: Cystathionine gamma-lyase - Lodderomyces
elongisporus (Yeast) (Saccharomyces elongisporus)
Length = 406
Score = 183 bits (445), Expect = 4e-45
Identities = 91/216 (42%), Positives = 135/216 (62%), Gaps = 12/216 (5%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNI-EKVKNAMQENTK 179
T ++ L G HI+S DVYGGT+R +V + G+ F N+ + ++ ++ TK
Sbjct: 87 TALIIQSLPIGSHIISGGDVYGGTHRYFTKVANHHGVEAQFV--ANLADDLEATLRPETK 144
Query: 180 MIWIETPTNPLLKVVDIEAIVKIARSRGD-----IIVVVDNTFLTPYLQKPLDFGADIVM 344
++W+ETP+NP L+V DI + +I ++ D +I+VVDNTFL+PY+ PL FGAD+V+
Sbjct: 145 LVWVETPSNPTLQVTDIAKVKQILQNHQDKTGNKVILVVDNTFLSPYISNPLKFGADVVV 204
Query: 345 YSLTKYMNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRME 524
+S+TKY+NGHSDV+MG ND + +K RFLQNA+G +PSP D + +R LKTL LR+
Sbjct: 205 HSVTKYINGHSDVVMGVLATNDSELHEKFRFLQNAIGSIPSPFDSWLAHRGLKTLHLRLR 264
Query: 525 HHKKSSLIIANWLE------KHPKIVEVLHPXLXTH 614
S+ IA +L+ I+ V +P L TH
Sbjct: 265 QASNSAQKIAEFLQSKIDNHNDGSIIHVNYPGLSTH 300
>UniRef50_A1ZDN6 Cluster: Cystathionine beta-lyase; n=1; Microscilla
marina ATCC 23134|Rep: Cystathionine beta-lyase -
Microscilla marina ATCC 23134
Length = 380
Score = 182 bits (443), Expect = 7e-45
Identities = 90/205 (43%), Positives = 133/205 (64%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
+TTL+ALL DH++ D+YGGT R + R GI +F D TNIE + A+Q NTK+
Sbjct: 81 STTLLALLKKEDHVLFQADLYGGTQRFITTDFPRFGIEYSFGDATNIEMFEEAIQFNTKL 140
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
I+IETP+NPLL++ DIE IV +A+ G ++ ++DNTF +P Q P+ G D+VM+S TKY
Sbjct: 141 IYIETPSNPLLRLTDIEKIVALAKQYG-VLTMIDNTFASPINQNPIPMGIDLVMHSGTKY 199
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
+ GHSD+ G AI+ K + +++ G + CY + RSLKTLALR+ ++
Sbjct: 200 LGGHSDLSCG-AIIGSKGLVAQIKSTATHFGGNLNAQTCYLLERSLKTLALRVRQQTYNA 258
Query: 543 LIIANWLEKHPKIVEVLHPXLXTHP 617
+A ++EKHPK+ +V +P L +HP
Sbjct: 259 QKLAEFMEKHPKVKKVHYPGLESHP 283
>UniRef50_A0LLP6 Cluster: Cystathionine gamma-synthase; n=1;
Syntrophobacter fumaroxidans MPOB|Rep: Cystathionine
gamma-synthase - Syntrophobacter fumaroxidans (strain
DSM 10017 / MPOB)
Length = 400
Score = 181 bits (441), Expect = 1e-44
Identities = 86/205 (41%), Positives = 133/205 (64%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
TTTL+ L+ GDH+V++D +YG + L+ +R GI TF D ++ ++ A+ NTK+
Sbjct: 97 TTTLLTFLSQGDHVVATDSIYGASRMALQFEFARFGIGATFVDSSSTANIERAIGRNTKV 156
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
I++ETPTNP + V DI A ++AR+RG I+VV DNTF PYLQ+PL+ GADIV+ SLTK+
Sbjct: 157 IFLETPTNPTMAVSDIRAAAELARARGAILVV-DNTFAGPYLQRPLELGADIVVESLTKF 215
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
+NGHSDV+ G + ++ + +++ + G P + + R LKTL LR+E + ++
Sbjct: 216 INGHSDVLGGMVVTRNEELHAQIKRMFTLFGGTIDPHQAWLILRGLKTLPLRVEKAQDNA 275
Query: 543 LIIANWLEKHPKIVEVLHPXLXTHP 617
+A +L HPK+ + +P L HP
Sbjct: 276 GRLARFLSGHPKVTWLRYPGLPDHP 300
>UniRef50_Q96VU8 Cluster: Cystathionine beta-lyase; n=3;
Pezizomycotina|Rep: Cystathionine beta-lyase -
Neurospora crassa
Length = 457
Score = 181 bits (441), Expect = 1e-44
Identities = 91/203 (44%), Positives = 126/203 (62%), Gaps = 1/203 (0%)
Frame = +3
Query: 12 LVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWI 191
+ LL GD +++ DD+YGGTNRLL + + G+ D TN+E V+ + T M+ +
Sbjct: 121 ITRLLKPGDEVITGDDLYGGTNRLLTYLKNNQGVIVHHVDTTNVESVRQIISPKTTMVLL 180
Query: 192 ETPTNPLLKVVDIEAIVKIARSRGD-IIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMN 368
ETPTNPL+K+ DI I +I + +VVVDNT L+P L PLD GADIV S TKY++
Sbjct: 181 ETPTNPLIKICDIPTIARITHEANEKAVVVVDNTMLSPMLFNPLDVGADIVYESGTKYLS 240
Query: 369 GHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLI 548
GH D++ G VND +GDKL F NA G SP D + + R +KTLA+RME + ++
Sbjct: 241 GHHDIMAGVIAVNDTELGDKLYFTINATGCGLSPNDSFLLMRGVKTLAIRMEKQQANAQR 300
Query: 549 IANWLEKHPKIVEVLHPXLXTHP 617
IA +LE H +V +P L +HP
Sbjct: 301 IAEFLESHG--FKVRYPGLKSHP 321
>UniRef50_A5GJ98 Cluster: MetC/metB Cystathionine
beta-lyase/cystathioninegamma-synthase; n=21;
Cyanobacteria|Rep: MetC/metB Cystathionine
beta-lyase/cystathioninegamma-synthase - Synechococcus
sp. (strain WH7803)
Length = 393
Score = 178 bits (433), Expect = 1e-43
Identities = 80/204 (39%), Positives = 128/204 (62%)
Frame = +3
Query: 6 TTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMI 185
T + + L GD ++ +++YG T RL QV ++ G+ T + DFT+ + ++ M+
Sbjct: 91 TAIASTLQQGDLVLCEENLYGCTVRLFEQVFAKFGVRTEWVDFTDPSALTAIVERQPAMV 150
Query: 186 WIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYM 365
W+E+PTNPLLKV+D+EA+ AR ++ VVVDNTF T +Q+PL GA + + S TKY+
Sbjct: 151 WLESPTNPLLKVIDLEAVCSAARG-AEVPVVVDNTFATALVQRPLQLGATLSLTSTTKYI 209
Query: 366 NGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSL 545
NGHSD + GA + ++ F Q A+G++PSP DC+ + R +KTL LR+ +++
Sbjct: 210 NGHSDALGGAVCTDAPDWHARMVFAQKALGLMPSPFDCWLITRGIKTLPLRLRQQIENAA 269
Query: 546 IIANWLEKHPKIVEVLHPXLXTHP 617
++AN L +HP++ V +P HP
Sbjct: 270 VLANHLAEHPQVDWVRYPHRADHP 293
>UniRef50_P53780 Cluster: Cystathionine beta-lyase, chloroplast
precursor; n=11; cellular organisms|Rep: Cystathionine
beta-lyase, chloroplast precursor - Arabidopsis thaliana
(Mouse-ear cress)
Length = 464
Score = 177 bits (432), Expect = 2e-43
Identities = 82/199 (41%), Positives = 134/199 (67%)
Frame = +3
Query: 21 LLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWIETP 200
L+ +G+ IV+ DDVYGG++RLL QVV R G+ + T +++V A+ TK++W+E+P
Sbjct: 167 LIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRVNTTKLDEVAAAIGPQTKLVWLESP 226
Query: 201 TNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNGHSD 380
TNP ++ DI I ++A ++G +V+VDN+ ++P L +PL+ GADIVM+S TK++ GHSD
Sbjct: 227 TNPRQQISDIRKISEMAHAQG-ALVLVDNSIMSPVLSRPLELGADIVMHSATKFIAGHSD 285
Query: 381 VIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLIIANW 560
V+ G V + + ++ FLQN+ G +P DC+ R +KT+ALR+E ++++ IA +
Sbjct: 286 VMAGVLAVKGEKLAKEVYFLQNSEGSGLAPFDCWLCLRGIKTMALRIEKQQENARKIAMY 345
Query: 561 LEKHPKIVEVLHPXLXTHP 617
L HP++ +V + L HP
Sbjct: 346 LSSHPRVKKVYYAGLPDHP 364
>UniRef50_Q12L75 Cluster: Methionine gamma-lyase; n=1; Shewanella
denitrificans OS217|Rep: Methionine gamma-lyase -
Shewanella denitrificans (strain OS217 / ATCC BAA-1090 /
DSM 15013)
Length = 390
Score = 175 bits (426), Expect = 9e-43
Identities = 87/205 (42%), Positives = 135/205 (65%), Gaps = 1/205 (0%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
+ L+ L GDH+++S VYG T L+ +SR GI+T+ DF++++ V+ A++ NT++
Sbjct: 90 SAALLTHLEQGDHLIASKAVYGCTYALITTQLSRYGISTSLVDFSDMQAVEAAIKPNTRV 149
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
++ ETP NP L+V D++A+ K+A+ G +I +VDNTF+TP LQKPL G D+V++S TKY
Sbjct: 150 LFCETPVNPHLQVFDLDAMAKVAKKHG-LISIVDNTFMTPLLQKPLAMGIDMVIHSATKY 208
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRF-LQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKS 539
+NGH DVI G N + + KLR+ + G V SP D + + R LKTL +R+ H +
Sbjct: 209 LNGHGDVIAGIVCGNSEHM-HKLRYEILKDFGGVMSPHDAWLILRGLKTLDVRLARHCDN 267
Query: 540 SLIIANWLEKHPKIVEVLHPXLXTH 614
+ I+AN+L +H +V +P L TH
Sbjct: 268 AEILANYLVEHKAFSQVFYPGLSTH 292
>UniRef50_Q8XNZ9 Cluster: Cystathionine gamma-synthase; n=7;
Bacteria|Rep: Cystathionine gamma-synthase - Clostridium
perfringens
Length = 384
Score = 175 bits (425), Expect = 1e-42
Identities = 84/204 (41%), Positives = 134/204 (65%), Gaps = 1/204 (0%)
Frame = +3
Query: 6 TTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGIN-TTFTDFTNIEKVKNAMQENTKM 182
T +++L GD ++ ++++YGGT R++ ++ S GI DFTNIE+ + ++ K
Sbjct: 79 TAVLSLFKSGDKLLITNNLYGGTFRVIDKIFSNFGIGYEIIDDFTNIEE---KIDKSVKA 135
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
I+IETPTNPLL V+DI+ I + +++ +VDNTF+TPY Q PL+ GADIV++S TKY
Sbjct: 136 IYIETPTNPLLDVIDIK-IASDKAKKYNLLTIVDNTFMTPYFQNPLNLGADIVIHSATKY 194
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
+ GHSD++ G +V D+ +G+K+ F+QN+ G + P D + + R +KTL++RM+ H+ ++
Sbjct: 195 LGGHSDLVAGLVVVKDEELGEKIHFIQNSTGGILQPFDSFLLIRGIKTLSVRMDRHELNA 254
Query: 543 LIIANWLEKHPKIVEVLHPXLXTH 614
IA L I V +P L TH
Sbjct: 255 NFIAEKLGDLEGIDNVYYPGLKTH 278
>UniRef50_Q49UL2 Cluster: Cystathionine beta-lyase cystathionine
gamma-synthase; n=16; Staphylococcus|Rep: Cystathionine
beta-lyase cystathionine gamma-synthase - Staphylococcus
saprophyticus subsp. saprophyticus (strain ATCC 15305
/DSM 20229)
Length = 391
Score = 175 bits (425), Expect = 1e-42
Identities = 83/198 (41%), Positives = 127/198 (64%)
Frame = +3
Query: 6 TTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMI 185
+ ++ LN GDH++ DDVYGGT RL Q+++R I + D T++ +++ A+Q+NTK+I
Sbjct: 80 SAVLLTLNAGDHVILPDDVYGGTFRLTEQILTRFNIQFSTIDTTHLNEIEEAIQDNTKLI 139
Query: 186 WIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYM 365
+IETP+NPL K+ DI IA+ + + VDNTF+TP Q PL GADIV++S TK++
Sbjct: 140 YIETPSNPLFKITDIRGAADIAKKH-HLKLAVDNTFMTPLGQSPLALGADIVVHSATKFL 198
Query: 366 NGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSL 545
+GH+D+I G AI ND+ I D L LQN G S D + + + LKTL +R +++
Sbjct: 199 SGHTDIIAGVAITNDQTIADALYLLQNGTGTALSAQDSWTLAKHLKTLPVRFNQSVENTK 258
Query: 546 IIANWLEKHPKIVEVLHP 599
+ +L + +I EV +P
Sbjct: 259 KLYEYLAQRDEIAEVYYP 276
>UniRef50_A1ID11 Cluster: Cystathionine gamma-synthase; n=1;
Candidatus Desulfococcus oleovorans Hxd3|Rep:
Cystathionine gamma-synthase - Candidatus Desulfococcus
oleovorans Hxd3
Length = 392
Score = 174 bits (423), Expect = 2e-42
Identities = 83/206 (40%), Positives = 127/206 (61%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
TTTL LL GDHI+ +DD Y T + + + I T + E ++ A++ NT++
Sbjct: 93 TTTLFGLLKSGDHIIITDDAYRRTLEFCKACLVKFDIECTVVKMCDYEAMEKAIKPNTRL 152
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
+ E+PTNP L ++D+E ++ I + +G I+VV D+TF TPY QKPL++G DIV++S TKY
Sbjct: 153 FFSESPTNPYLNIMDLERLIGIFKDKG-ILVVSDSTFATPYNQKPLEYGVDIVIHSATKY 211
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
+ GH+D++ G + + K + FL+ G++ P Y + R LKT LRME ++
Sbjct: 212 LAGHNDLLSGVVLGSKKLVEPVREFLKITGGVI-DPNSAYLLIRGLKTFGLRMERLNENG 270
Query: 543 LIIANWLEKHPKIVEVLHPXLXTHPH 620
I+A LE+HPKI V +P L +HPH
Sbjct: 271 QIVAEGLERHPKISRVYYPGLPSHPH 296
>UniRef50_Q5WAZ1 Cluster: Methionine gamma-lyase; n=1; Bacillus
clausii KSM-K16|Rep: Methionine gamma-lyase - Bacillus
clausii (strain KSM-K16)
Length = 402
Score = 173 bits (421), Expect = 3e-42
Identities = 83/200 (41%), Positives = 122/200 (61%)
Frame = +3
Query: 18 ALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWIET 197
A LN GDH ++ + Y T L + +L ++ TF D ++I K A+Q NTK+++ ET
Sbjct: 105 AFLNPGDHFIAVHNCYSETKILHESLAEQLSVDVTFIDSSDIHHYKQAIQPNTKLVFAET 164
Query: 198 PTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNGHS 377
P NP L +VDI + + + D + VVD+TF TPY QKPL GADIV++S TKY+ GHS
Sbjct: 165 PANPTLSLVDISKVATLVHEQSDAVFVVDSTFATPYNQKPLKHGADIVVHSATKYLGGHS 224
Query: 378 DVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLIIAN 557
DV+ G + + I DK+R + G P + + R ++TL LRME H +++L +A
Sbjct: 225 DVVAGVCAGSTELI-DKVRHKYSFHGPHLDPFGAWLLCRGIRTLGLRMEKHNENALKLAQ 283
Query: 558 WLEKHPKIVEVLHPXLXTHP 617
+LE HPKI +V +P +HP
Sbjct: 284 FLETHPKIRQVFYPFSESHP 303
>UniRef50_Q5MQ31 Cluster: L-methionine-gamma-lyase; n=3;
Micrococcineae|Rep: L-methionine-gamma-lyase -
Brevibacterium linens
Length = 425
Score = 173 bits (421), Expect = 3e-42
Identities = 84/207 (40%), Positives = 128/207 (61%), Gaps = 7/207 (3%)
Frame = +3
Query: 18 ALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWIET 197
ALL GD I+ D+YGGT RLL+ R GI+ D T+ E + A+ T ++W+ET
Sbjct: 90 ALLGPGDEIIIPRDIYGGTYRLLKNEYERWGISIRTVDLTDTEALAAAISAKTAIVWVET 149
Query: 198 PTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNGHS 377
P+NP L +VDI K+A + + I+ VD+TF TP LQ+P++ GAD+V++S TK++NGHS
Sbjct: 150 PSNPGLDIVDIAETAKLAHA-ANAILAVDSTFATPILQRPIELGADVVIHSTTKFINGHS 208
Query: 378 DVIMGAAIVNDKA-------IGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKK 536
DVI GA + D + + ++L ++G+ +P D + R +KTL +RM H +
Sbjct: 209 DVIGGAVLAGDGSTCPRAAKVVERLESYLASVGLGIAPFDAWLTRRGIKTLPVRMAKHCE 268
Query: 537 SSLIIANWLEKHPKIVEVLHPXLXTHP 617
++ +A WLE P+I EV +P L +HP
Sbjct: 269 NAQAVAQWLESRPEIAEVYYPGLPSHP 295
>UniRef50_Q9KEQ0 Cluster: Methionine gamma lyase; n=13;
Bacillaceae|Rep: Methionine gamma lyase - Bacillus
halodurans
Length = 393
Score = 173 bits (420), Expect = 5e-42
Identities = 84/202 (41%), Positives = 130/202 (64%)
Frame = +3
Query: 12 LVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWI 191
LV L DHI+ S+ VYG T LL + + I+ TF+ ++E++ +Q+NT I++
Sbjct: 94 LVGLTKANDHILVSNGVYGCTFGLLTMLKEKYNIDATFSPMDSVEEILANIQDNTTCIYV 153
Query: 192 ETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNG 371
ETP NP ++++D+E +V++A+ +G I V+VDNTF TPYLQ+P+ G D V++S TKY+ G
Sbjct: 154 ETPINPTMQLIDLELVVRVAKEKG-IKVIVDNTFATPYLQQPIALGCDFVVHSATKYIGG 212
Query: 372 HSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLII 551
H DV+ G I + + I + Q MG V SP D + + R LKTLA+RM+ H +++ +
Sbjct: 213 HGDVVAGVLIGDKETIQLIRKTTQKDMGGVISPFDAWLLLRGLKTLAVRMDRHCENAEKL 272
Query: 552 ANWLEKHPKIVEVLHPXLXTHP 617
A L++HPK+ VL+P HP
Sbjct: 273 AEKLKEHPKVSTVLYPGDFEHP 294
>UniRef50_Q181I0 Cluster: Methionine gamma-lyase; n=2; Clostridium
difficile|Rep: Methionine gamma-lyase - Clostridium
difficile (strain 630)
Length = 384
Score = 172 bits (419), Expect = 6e-42
Identities = 83/207 (40%), Positives = 134/207 (64%), Gaps = 2/207 (0%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
T+T++AL+ GDHIVSSD ++ T + +++S+ G+ TF D N + VK AM+ NTK+
Sbjct: 91 TSTILALVKSGDHIVSSDGIFSHTKLFMSELLSKFGVEVTFVDAVNPQNVKEAMRPNTKI 150
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
++IE+P NP L +VDI+ I +IA + +VD+TF TP +Q+P+D GAD+V++SLTK+
Sbjct: 151 VYIESPLNPSLDLVDIKTIAEIAHENKS-LAIVDSTFGTPIVQRPIDLGADLVIHSLTKF 209
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRF--LQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKK 536
+NGH D +G A+ K + D +R+ L G P+ + + R +KTL +RM+ H +
Sbjct: 210 INGHGDT-LGGAVAGSKELIDLVRWPSLCCFTGASLPPMSAWMILRGMKTLDMRMKKHCE 268
Query: 537 SSLIIANWLEKHPKIVEVLHPXLXTHP 617
+ L +A +LE+ + V +P L +HP
Sbjct: 269 NGLAVAEFLEEEENVELVKYPALKSHP 295
>UniRef50_Q8TMW7 Cluster: Methionine gamma-lyase; n=3;
Methanosarcina|Rep: Methionine gamma-lyase -
Methanosarcina acetivorans
Length = 406
Score = 172 bits (419), Expect = 6e-42
Identities = 83/205 (40%), Positives = 129/205 (62%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
T +++ L GDH++S+D VYG T L +++ GI+ +F D ++I+KV+ A + T+M
Sbjct: 93 TAVVLSTLKQGDHLISTDVVYGCTYSLFSEILPGFGIDVSFVDTSDIKKVRAAFKPETRM 152
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
+++ETP NP + V DI I K+A+++G I +VDNTF TPY QKPL+ GADI + S TKY
Sbjct: 153 VFLETPANPTITVCDIREISKLAKAQG-AICIVDNTFATPYFQKPLELGADISLSSCTKY 211
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
+ GH+D ++G +V + L + G + + + R LKTL +RME H +++
Sbjct: 212 IGGHAD-LLGGIVVGSRDFMKSLGKVVGYTGGIMGLHEAWLCIRGLKTLHIRMERHAENA 270
Query: 543 LIIANWLEKHPKIVEVLHPXLXTHP 617
L +AN+LE HP + V +P L HP
Sbjct: 271 LTVANFLEAHPTVEWVRYPGLSNHP 295
>UniRef50_Q1IQ68 Cluster: Cystathionine gamma-synthase; n=1;
Acidobacteria bacterium Ellin345|Rep: Cystathionine
gamma-synthase - Acidobacteria bacterium (strain
Ellin345)
Length = 400
Score = 172 bits (418), Expect = 8e-42
Identities = 79/201 (39%), Positives = 128/201 (63%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
TT +++L GDH V S+ +YGGT RL R+++ LGI +F D ++ V+ A++ TK+
Sbjct: 84 TTLFLSVLRAGDHAVLSEVIYGGTMRLFREILDHLGITASFVDTSDAANVERAIRPETKI 143
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
I+IETP NP LK+ DI A+ ++A+ R I++ VDNTFLT LQ + GADI + S TKY
Sbjct: 144 IFIETPGNPTLKLTDIAAVAEVAK-RHSILLAVDNTFLTSLLQNVFELGADISLLSTTKY 202
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
++GH+ + G+ +D+ + ++ R ++ +G +P + + + +KTL R++ H +++
Sbjct: 203 IDGHNATLGGSLATHDEKLLERFRLIRKTIGTTQAPFEAWLTLQGMKTLPARLKLHCENA 262
Query: 543 LIIANWLEKHPKIVEVLHPXL 605
IIA WLE HP + V P L
Sbjct: 263 QIIAEWLEAHPAVARVYFPGL 283
>UniRef50_A1HQW4 Cluster: Cystathionine gamma-synthase; n=1;
Thermosinus carboxydivorans Nor1|Rep: Cystathionine
gamma-synthase - Thermosinus carboxydivorans Nor1
Length = 392
Score = 171 bits (417), Expect = 1e-41
Identities = 87/200 (43%), Positives = 128/200 (64%)
Frame = +3
Query: 6 TTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMI 185
T + A + GDHIV+ +YGGT LL+ +++LG+ TF D ++ V A++ NTK++
Sbjct: 91 TAIFAEVRQGDHIVAHHVLYGGTYALLKNEMAKLGVEVTFVDCNDLSAVAQAIRPNTKIL 150
Query: 186 WIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYM 365
++ET NPL++V+DI AIV++AR+ V VDNTF +PY +PL GAD+V++S TKY+
Sbjct: 151 YLETICNPLMEVLDIPAIVQLART-VKAKVYVDNTFASPYHCQPLAHGADVVLHSATKYL 209
Query: 366 NGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSL 545
NGHSD + G IV D K + + G SP D + R LKTLALRM H +++L
Sbjct: 210 NGHSDAMAG-VIVADSDFIAKAKNVGTTYGATLSPFDAWLTLRGLKTLALRMHRHAENAL 268
Query: 546 IIANWLEKHPKIVEVLHPXL 605
+A +L+ HPK+ V +P L
Sbjct: 269 ALAKYLQVHPKVTGVNYPGL 288
>UniRef50_Q8G436 Cluster: Possible cystathionine gamma lyase; n=3;
Bacteria|Rep: Possible cystathionine gamma lyase -
Bifidobacterium longum
Length = 507
Score = 171 bits (416), Expect = 1e-41
Identities = 93/207 (44%), Positives = 124/207 (59%), Gaps = 3/207 (1%)
Frame = +3
Query: 9 TLVALLNHGDHIVSSDDVYGGTNRLLRQVV-SRLGINTTFTDFTNIEKVKNAMQENTKMI 185
T LN GDH + SD Y RLL Q++ + GI T+ D ++ E V+ A++ NTK++
Sbjct: 200 TFTTFLNRGDHAIFSDTTYIAAYRLLNQILPEKYGIETSILDTSDPENVRAALRPNTKLV 259
Query: 186 WIETPTNPLLKVVDIEAIVKIARSRG-DIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
IETP NP LKV DI I K+A DI+V VDNTF TPY +PL+ GADIV+ SLTKY
Sbjct: 260 HIETPANPTLKVSDIATIAKLAHEANPDILVSVDNTFNTPYNVRPLNLGADIVIESLTKY 319
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRF-LQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKS 539
+NGH D +G +I KA D++RF Q G + SP + + +NR TL LR+ H
Sbjct: 320 INGHGDA-LGGSIATTKARTDQIRFTAQVNFGGIISPFNAWLINRGSVTLPLRIRQHNAL 378
Query: 540 SLIIANWLEKHPKIVEVLHPXLXTHPH 620
+L IA LE + V +P L +HPH
Sbjct: 379 ALAIAKHLESLDVVRFVAYPGLESHPH 405
>UniRef50_UPI0000E46EAD Cluster: PREDICTED: similar to methionine
gamma-lyase; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to methionine gamma-lyase -
Strongylocentrotus purpuratus
Length = 364
Score = 169 bits (412), Expect = 4e-41
Identities = 81/205 (39%), Positives = 121/205 (59%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
TTT++AL+ GDH+++ D V+GGT + ++ G+ TTF +IE + A+Q NTK+
Sbjct: 125 TTTVLALIKTGDHVIAPDPVFGGTYKFFNSMLMDFGVETTFVPAGDIEAYRKAIQPNTKI 184
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
+ ETPTNP L ++D++A +A+S I + D+TF TPYLQ L G DI S +KY
Sbjct: 185 FYGETPTNPTLTLLDLKAFADVAKSVPGAISMSDSTFATPYLQDTLGLGVDISFQSCSKY 244
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
+ GH D++ G+ D + L Q +G P + R ++TL LRME H ++
Sbjct: 245 LGGHGDLLGGSMCTKDPELYLFLTEYQRQIGNTMGPFTASILLRGIRTLPLRMEKHSSNA 304
Query: 543 LIIANWLEKHPKIVEVLHPXLXTHP 617
L IA +LE HPK+ V +P L +HP
Sbjct: 305 LKIAQYLETHPKVARVKYPGLKSHP 329
>UniRef50_Q67R76 Cluster: Cystathionine gamma-lyase; n=13;
Bacteria|Rep: Cystathionine gamma-lyase -
Symbiobacterium thermophilum
Length = 401
Score = 169 bits (412), Expect = 4e-41
Identities = 83/204 (40%), Positives = 133/204 (65%), Gaps = 1/204 (0%)
Frame = +3
Query: 12 LVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWI 191
+ AL+ GDH++ + +YG T L V++R G+ T D +V+ A++ NT+++
Sbjct: 96 VTALVRAGDHVLFGNPIYGCTYDFLMDVMARFGVEATPVDPARPGQVERAIRPNTRLLLF 155
Query: 192 ETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNG 371
ETP NP L++ DI A+ +A R I VVVDNTF++PYLQ+PL+ GAD+V++S TK++ G
Sbjct: 156 ETPANPTLRLADIRALSDLAH-RHQITVVVDNTFMSPYLQRPLEHGADMVVHSATKFIGG 214
Query: 372 HSDVIMGAAIVNDKAIGD-KLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLI 548
H DV+ G A+ + + + L+N GI+ SP D + + R LKTLA+RME H +++L
Sbjct: 215 HGDVVAGLAVGPAEVMARVRSTTLKNFGGIL-SPFDAWLLLRGLKTLAIRMERHSENALK 273
Query: 549 IANWLEKHPKIVEVLHPXLXTHPH 620
+A +LE+HP ++ V +P L + P+
Sbjct: 274 VARYLEQHPLVMRVYYPGLESSPY 297
>UniRef50_Q1IQD6 Cluster: Cystathionine gamma-synthase; n=2;
Acidobacteria|Rep: Cystathionine gamma-synthase -
Acidobacteria bacterium (strain Ellin345)
Length = 390
Score = 169 bits (410), Expect = 7e-41
Identities = 83/207 (40%), Positives = 129/207 (62%), Gaps = 2/207 (0%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
T ++ +L+ GDH+V D+Y G L+ + +R GI T D N+++ + A++ TK+
Sbjct: 90 TFSVFQILSPGDHVVLHRDMYYGVRELINGIFTRYGIQHTVVDMRNLDETRAAVRPGTKL 149
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
W+ETPTNPL++VV IE I IA G + +NTF TP LQ+PL+ GAD+V++SLTKY
Sbjct: 150 FWLETPTNPLIEVVAIEPIAAIAHEHG-ALFACENTFATPALQRPLELGADLVVHSLTKY 208
Query: 363 MNGHSDVIMGAAIVNDKA--IGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKK 536
++GHSD MG A++ +A + K+R Q+ G V SP DC+ + R +++L RM H +
Sbjct: 209 LSGHSDA-MGGAVILKRAGDLAHKIRDFQHNGGAVLSPFDCWLILRGIESLPARMRIHCE 267
Query: 537 SSLIIANWLEKHPKIVEVLHPXLXTHP 617
++ IA +L H + +V +P L P
Sbjct: 268 NAQKIAEFLSAHAAVSKVRYPGLTNDP 294
>UniRef50_Q38DH3 Cluster: Cystathione gamma lyase, putative; n=7;
Trypanosomatidae|Rep: Cystathione gamma lyase, putative
- Trypanosoma brucei
Length = 445
Score = 169 bits (410), Expect = 7e-41
Identities = 78/205 (38%), Positives = 128/205 (62%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
TT + AL+N GDH + +D YGGTNR R +R G+ TF D ++ V+ A++ NTK+
Sbjct: 138 TTVVSALMNAGDHAIVTDCSYGGTNRACRVFFTRFGMEFTFVDMRDLSNVEKAIKSNTKL 197
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
+ ETP NP L + DI A+ KI +++G ++ V DNTF T ++ +P+D GAD+ + S TK+
Sbjct: 198 VISETPANPTLTLTDIRALSKICKAKG-LLHVCDNTFATAFIMRPIDLGADVSLISTTKF 256
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
++GH+ + GA + K + +KLR QN +G SP + +++KT++LR+ ++
Sbjct: 257 VDGHNMTVGGALVTKRKDLDEKLRLTQNILGNAMSPFVAFLQLQTMKTMSLRVTKQSANA 316
Query: 543 LIIANWLEKHPKIVEVLHPXLXTHP 617
+A +LE HP + +V +P L + P
Sbjct: 317 QKVAEFLETHPIVDKVSYPGLKSFP 341
>UniRef50_Q9KFD9 Cluster: Cystathionine gamma-synthase; n=3;
Bacillus|Rep: Cystathionine gamma-synthase - Bacillus
halodurans
Length = 381
Score = 168 bits (409), Expect = 1e-40
Identities = 81/196 (41%), Positives = 127/196 (64%)
Frame = +3
Query: 12 LVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWI 191
L+ALL GDH+++++D+YGGT +LL + + +LGI+ +F F E VK A+++ TK+++
Sbjct: 92 LLALLEKGDHLIAANDLYGGTYQLLAEELPKLGIDVSFVPFQEREVVKRAIRKETKVLYS 151
Query: 192 ETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNG 371
ET TNPLL+V DI +V++ + G + V+DNTF TPY +PL G D+V++S TKY+ G
Sbjct: 152 ETVTNPLLRVEDIHQVVELGKEHG-LSTVIDNTFATPYFVQPLTCGVDVVVHSATKYIGG 210
Query: 372 HSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLII 551
HSDV G +V I ++R +G SP + + +R LKTLALRME +++ +
Sbjct: 211 HSDVTAG-VVVGSAEIIQQVRQKVATLGCNLSPFEAWLASRGLKTLALRMERQGENAQAL 269
Query: 552 ANWLEKHPKIVEVLHP 599
A + HP + +V +P
Sbjct: 270 ATFFADHPGVSQVFYP 285
>UniRef50_A6GHC8 Cluster: Cystathionine gamma-synthase; n=1;
Plesiocystis pacifica SIR-1|Rep: Cystathionine
gamma-synthase - Plesiocystis pacifica SIR-1
Length = 369
Score = 167 bits (405), Expect = 3e-40
Identities = 79/204 (38%), Positives = 128/204 (62%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
TTTL+A+L G H++ + DVY T R +++ G+ T +E ++ A+++ T++
Sbjct: 70 TTTLLAMLRAGQHVIFTADVYRKTRLFARSYLAKFGVEFDIVAPT-LEAIEGAVRDTTRI 128
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
I+ E PTNP L+VVD+E +V +A++R I ++D TF TP +PL G D+V++S TKY
Sbjct: 129 IFTEAPTNPYLRVVDLEGVVALAKARR-IKTIIDATFATPINMRPLSLGVDLVIHSTTKY 187
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
+ GH+D ++G ++ + D +R +G V P + Y ++R LKTLALR+E H S+
Sbjct: 188 LGGHND-LLGGVVIGKSGLVDAIREQVGTLGAVCDPHNAYLLSRGLKTLALRVERHNHSA 246
Query: 543 LIIANWLEKHPKIVEVLHPXLXTH 614
L +A LE HPK+ +V +P L +H
Sbjct: 247 LALARVLEAHPKVAKVWYPLLESH 270
>UniRef50_A7H124 Cluster: Methionine gamma-lyase; n=2;
Campylobacter|Rep: Methionine gamma-lyase -
Campylobacter curvus 525.92
Length = 380
Score = 166 bits (404), Expect = 4e-40
Identities = 81/198 (40%), Positives = 127/198 (64%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
TT + LL GD ++ +++VYGGT R + GI+ D N+ + ++ + ++ KM
Sbjct: 78 TTAVFNLLKSGDKVLLNNNVYGGTYRYASGIFKNQGISYELVDDLNLIE-EDDITDDVKM 136
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
++IETP+NPLL+V DI+ IV +A +G +VVVDNTFLTPY Q+ L G DIV+YS TKY
Sbjct: 137 VFIETPSNPLLRVTDIKRIVNLAHKKG-ALVVVDNTFLTPYYQRLLPLGVDIVVYSATKY 195
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
+ GH+DVI G ND A+ D++ F++N +G SP D Y++ R LKTL++R + +++
Sbjct: 196 IGGHADVIAGIVSTNDDALADRIAFMKNTLGATLSPTDAYYLIRGLKTLSVRFDRQTQNT 255
Query: 543 LIIANWLEKHPKIVEVLH 596
I +L+ + + V +
Sbjct: 256 HKIVEFLKSNSAVRTVYY 273
>UniRef50_Q86D27 Cluster: Methionine gamma-lyase 2; n=3; Entamoeba
histolytica|Rep: Methionine gamma-lyase 2 - Entamoeba
histolytica
Length = 392
Score = 166 bits (404), Expect = 4e-40
Identities = 79/201 (39%), Positives = 123/201 (61%)
Frame = +3
Query: 15 VALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWIE 194
+ LL GDH++S D +YG T L +G++ +F + + E V A + NTKM+++E
Sbjct: 95 MGLLKAGDHLISGDTLYGCTVELFGNRFKDMGVDVSFVNTASDEAVVKAWKPNTKMVYLE 154
Query: 195 TPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNGH 374
+P NP KV DI+ I KI +G I+VV D TF TP L+ GAD+V++S+TKY+NGH
Sbjct: 155 SPANPTCKVSDIKGIAKICHEKGAILVV-DCTFTTPVFLPALELGADVVLHSITKYINGH 213
Query: 375 SDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLIIA 554
DV+ G + + K++ + G + +P+D + R +KTL +RM+ H ++ L +A
Sbjct: 214 GDVVGGVVTTKNPELLQKIKAFRKDTGSLMAPMDAFLCIRGVKTLPMRMKVHMENGLKVA 273
Query: 555 NWLEKHPKIVEVLHPXLXTHP 617
+LE+HPKI +V HP L + P
Sbjct: 274 KFLEQHPKIKQVNHPGLESFP 294
>UniRef50_A4EYE9 Cluster: Cystathionine beta-lyase/cystathionine
gamma-synthase; n=2; Roseobacter|Rep: Cystathionine
beta-lyase/cystathionine gamma-synthase - Roseobacter
sp. SK209-2-6
Length = 453
Score = 166 bits (403), Expect = 5e-40
Identities = 79/205 (38%), Positives = 132/205 (64%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
T ++A+++ G H+V++ D+YGGT L Q G++ T D +++ ++ A+Q NT+
Sbjct: 134 TAGVLAMVDKGAHVVAASDLYGGTYNLFNQEFPSFGMSATLVDSYDLDAIEEAIQPNTQA 193
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
++ E TNP+LKVV+I A+V+IA+ R ++ ++VD+TF P + +PL+ G D+V++S +KY
Sbjct: 194 LYFEAITNPVLKVVNIPALVEIAK-RHNLRLIVDSTFAPPPVMRPLELGVDLVIHSASKY 252
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
+NGHSD+I G K + L N G + P C+ + R LKTL +RM H++S+
Sbjct: 253 LNGHSDLIAGVVAGPRKLVDTVWPRLLNFGGSL-DPHACFLLERGLKTLPIRMRAHEESA 311
Query: 543 LIIANWLEKHPKIVEVLHPXLXTHP 617
+A +LE HP + +VL+P L +HP
Sbjct: 312 TALAKFLESHPMVEKVLYPMLPSHP 336
>UniRef50_A6QZA3 Cluster: Cystathionine gamma-lyase; n=1;
Ajellomyces capsulatus NAm1|Rep: Cystathionine
gamma-lyase - Ajellomyces capsulatus NAm1
Length = 457
Score = 166 bits (403), Expect = 5e-40
Identities = 76/148 (51%), Positives = 105/148 (70%)
Frame = +3
Query: 174 TKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSL 353
T+ I + +P+NP L +VDI I +A G I+VVVDNTFL+PY+Q PLD+GADIV++S+
Sbjct: 196 TRHISLRSPSNPTLGLVDIRKIASVAHQHG-IMVVVDNTFLSPYIQNPLDYGADIVVHSV 254
Query: 354 TKYMNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHK 533
TKY+NGHSDV+MG A+ N + ++L FLQNA+G VPS DC+ +R LKTL LR
Sbjct: 255 TKYINGHSDVLMGVAVFNSPTLHERLSFLQNAIGAVPSAFDCWLAHRGLKTLHLRAREAS 314
Query: 534 KSSLIIANWLEKHPKIVEVLHPXLXTHP 617
K++ IAN LE P ++ V +P + +HP
Sbjct: 315 KNATAIANALESSPHVIAVNYPGIKSHP 342
>UniRef50_Q9KCE4 Cluster: Cystathionine gamma-synthase
(O-succinylhomoserine (Thiol)-lyase); n=44;
Bacteria|Rep: Cystathionine gamma-synthase
(O-succinylhomoserine (Thiol)-lyase) - Bacillus
halodurans
Length = 378
Score = 165 bits (401), Expect = 9e-40
Identities = 75/197 (38%), Positives = 127/197 (64%)
Frame = +3
Query: 9 TLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIW 188
T+ +L GD I++S D+YGGT RL + G++ ++ D N+ ++ + E T+ ++
Sbjct: 83 TVFSLFQSGDEIIASQDLYGGTYRLFEGGWKKWGLSFSYADPRNLAALEQQITEKTRALF 142
Query: 189 IETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMN 368
IETPTNPL++ +I + +A G ++++VDNTF TP LQ+PL+ G IV++S +KY+
Sbjct: 143 IETPTNPLMQEANIRELAALANKHG-LLLIVDNTFYTPLLQQPLNEGTHIVIHSASKYLG 201
Query: 369 GHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLI 548
GH+DVI G + + + +++ + N +G S D + + R +KTLALRME H+ ++
Sbjct: 202 GHNDVIAGLIVAKGQELCEQIAYYHNGIGGTLSAFDSWLLIRGMKTLALRMEQHQNNARA 261
Query: 549 IANWLEKHPKIVEVLHP 599
IA++LEKH + +VL+P
Sbjct: 262 IASYLEKHEGVTDVLYP 278
>UniRef50_Q8R9M2 Cluster: Cystathionine beta-lyases/cystathionine
gamma-synthases; n=5; Clostridia|Rep: Cystathionine
beta-lyases/cystathionine gamma-synthases -
Thermoanaerobacter tengcongensis
Length = 394
Score = 164 bits (399), Expect = 2e-39
Identities = 80/202 (39%), Positives = 127/202 (62%), Gaps = 1/202 (0%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
++ L +LL D +++ +YG + ++ ++ + G+ D T++E++K ++ + K+
Sbjct: 91 SSVLFSLLRPNDKVLAHKTLYGSSYNVITNLLPKYGVKYKLIDMTSLEELKESLDDTVKV 150
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
I+ ETP+NP L ++DIE + KIA RG I VVVDNTF TP Q PL GAD+V++S TKY
Sbjct: 151 IYFETPSNPDLSIIDIEEVSKIAYQRG-IKVVVDNTFATPCFQNPLLLGADVVVHSATKY 209
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRF-LQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKS 539
+ GH D + G AI D+A L+F G V SP + + + R +KTL LRM H+K+
Sbjct: 210 ICGHGDALGGVAISKDEAYIHYLKFDYMCEFGGVMSPFNAWLMLRGIKTLGLRMRQHEKN 269
Query: 540 SLIIANWLEKHPKIVEVLHPXL 605
++ +A +L +HPK+ VL+P L
Sbjct: 270 AMEVAKFLSRHPKVKNVLYPGL 291
>UniRef50_Q6AJ03 Cluster: Probable cystathionine beta-lyase; n=1;
Desulfotalea psychrophila|Rep: Probable cystathionine
beta-lyase - Desulfotalea psychrophila
Length = 386
Score = 164 bits (399), Expect = 2e-39
Identities = 79/203 (38%), Positives = 125/203 (61%)
Frame = +3
Query: 9 TLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIW 188
TL A GDHIV D+VY T+ +V+S+ G+ ++ + + +++NT +I+
Sbjct: 93 TLQAFTKAGDHIVVCDNVYWPTSNFCNKVLSKFGVEISYAPSAVGADIADYLRDNTSLIF 152
Query: 189 IETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMN 368
+E+P + ++ DIEAI +IAR+R DI+ ++D T+ TP + L FG D+ + S TKY++
Sbjct: 153 MESPGSNTFEIQDIEAITQIARAR-DIVTILDGTWGTPLYHRALSFGVDVSIQSATKYIS 211
Query: 369 GHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLI 548
GHSD+++G A VN K R+ Q+ P P DCY R LKTL +R++HH++S+L
Sbjct: 212 GHSDILLGTATVNHKYADILARYYQSLELFAP-PADCYAALRGLKTLHVRLKHHEQSALQ 270
Query: 549 IANWLEKHPKIVEVLHPXLXTHP 617
IA+WLE P+ ++HP HP
Sbjct: 271 IADWLESQPQTGRIIHPARPDHP 293
>UniRef50_Q0LLX7 Cluster: Cystathionine gamma-synthase; n=3;
Bacteria|Rep: Cystathionine gamma-synthase -
Herpetosiphon aurantiacus ATCC 23779
Length = 372
Score = 163 bits (397), Expect = 3e-39
Identities = 79/206 (38%), Positives = 126/206 (61%), Gaps = 1/206 (0%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
TT ++ L G ++ D Y GT L+RQV ++L + F D T++ V+ A++ +
Sbjct: 79 TTAVLQSLAPGQRVLLPRDCYNGTANLVRQVFAQL--DAQFVDMTDLAAVQAALEPAPAL 136
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
+W+ETP+NP L++ D+ A+ +A + G +VV DNT+ TP Q+P D G D+VM+S TKY
Sbjct: 137 VWLETPSNPTLRLTDLAAVSNLAHAVG-ALVVCDNTWATPLGQRPFDLGVDLVMHSTTKY 195
Query: 363 MNGHSDVIMGAAIVNDKAIG-DKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKS 539
+ GHSDV+ GA I +L+ + G VPSP +C+ + R +++LA R+ H +
Sbjct: 196 LGGHSDVLGGALITKTVTPWWQRLQQIHVLAGAVPSPFECWLILRGMQSLAYRLRGHCAN 255
Query: 540 SLIIANWLEKHPKIVEVLHPXLXTHP 617
+L +A WL +HPK+ V +P L +HP
Sbjct: 256 ALAVAEWLAQHPKVQAVHYPGLTSHP 281
>UniRef50_Q8RI67 Cluster: Cystathionine beta-lyase; n=2;
Bacteria|Rep: Cystathionine beta-lyase - Fusobacterium
nucleatum subsp. nucleatum
Length = 419
Score = 163 bits (395), Expect = 5e-39
Identities = 82/206 (39%), Positives = 131/206 (63%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
+++++A GDHI+S +YG T + +++ + G+ TTF DFTNIE+VK ++ NT +
Sbjct: 113 SSSIIAHTKTGDHILSDKTLYGETLEIFTKILQKYGVETTFVDFTNIEEVKKNIKSNTVI 172
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
++ ET +NPL+ V +++ + IA S + I +VDNTF+T L +PL FGADIV+ SLTK+
Sbjct: 173 LYTETVSNPLIGVPNLKVLANIAHS-NNAIFIVDNTFMTGALVQPLKFGADIVVNSLTKF 231
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
NGHSDV+ GAA + I K+ LQ +G P + R ++T+ LR++ +++
Sbjct: 232 ANGHSDVVCGAATGKSELI-KKIYELQVLLGTQSDPFSSWLTVRGMRTMELRIKKQCENA 290
Query: 543 LIIANWLEKHPKIVEVLHPXLXTHPH 620
+A LEK P I++V HP L +P+
Sbjct: 291 SALALELEKSPYILKVNHPSLVNNPY 316
>UniRef50_O15564 Cluster: Methionine gamma-lyase; n=2; Trichomonas
vaginalis|Rep: Methionine gamma-lyase - Trichomonas
vaginalis
Length = 396
Score = 162 bits (394), Expect = 6e-39
Identities = 73/204 (35%), Positives = 127/204 (62%), Gaps = 2/204 (0%)
Frame = +3
Query: 9 TLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIW 188
T++ +L GDH++S + +YG T+ L +++ GI F + +VK M+ NTK+++
Sbjct: 93 TVLTILKAGDHLISDECLYGCTHALFEHALTKFGIQVDFINTAIPGEVKKHMKPNTKIVY 152
Query: 189 IETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMN 368
ETP NP LK++D+E + K A S+ ++V+ DNTF +P + P+DFG D+V++S TKY+N
Sbjct: 153 FETPANPTLKIIDMERVCKDAHSQEGVLVIADNTFCSPMITNPVDFGVDVVVHSATKYIN 212
Query: 369 GHSDVIMGAAIVNDKAIGDKLRF--LQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
GH+DV+ G I + ++R +++ G V SP D + + R L TL +RM+ +++
Sbjct: 213 GHTDVVAG-LICGKADLLQQIRMVGIKDITGSVISPHDAWLITRGLSTLNIRMKAESENA 271
Query: 543 LIIANWLEKHPKIVEVLHPXLXTH 614
+ +A +L+ HP + +V +P H
Sbjct: 272 MKVAEYLKSHPAVEKVYYPGFEDH 295
>UniRef50_P44502 Cluster: Cystathionine gamma-synthase (EC 2.5.1.48)
(CGS) (O-succinylhomoserine (thiol)-lyase); n=14;
Bacteria|Rep: Cystathionine gamma-synthase (EC 2.5.1.48)
(CGS) (O-succinylhomoserine (thiol)-lyase) - Haemophilus
influenzae
Length = 369
Score = 162 bits (394), Expect = 6e-39
Identities = 76/197 (38%), Positives = 126/197 (63%), Gaps = 1/197 (0%)
Frame = +3
Query: 12 LVALLNHGDHIVSSDDVYGGTNRLLR-QVVSRLGINTTFTDFTNIEKVKNAMQENTKMIW 188
L+ L D + S DVYGGT RLL + + + + + ++ A+ NTK I+
Sbjct: 85 LMTLFTAPDEWIVSSDVYGGTYRLLDFSYKNNNSVKPVYVNTASASAIEAAINPNTKAIF 144
Query: 189 IETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMN 368
IETP+NPL++ D+ I K+A+ +++++VDNTFLTP L +PLD GAD+V++S TKY+
Sbjct: 145 IETPSNPLMEECDVVEIAKLAKKH-NLMLIVDNTFLTPVLSRPLDLGADVVIHSGTKYIA 203
Query: 369 GHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLI 548
GH+D ++G + + + D++ ++QN G V SP D + R +KTL+LRM+ H++++
Sbjct: 204 GHNDALVGLIVAKGQELCDRIAYIQNGAGAVLSPFDSWLTIRGMKTLSLRMKRHQENAQA 263
Query: 549 IANWLEKHPKIVEVLHP 599
IA +L+ P++ VL+P
Sbjct: 264 IAEFLKAQPQVESVLYP 280
>UniRef50_Q3JCU1 Cluster: Cystathionine gamma-synthase; n=1;
Nitrosococcus oceani ATCC 19707|Rep: Cystathionine
gamma-synthase - Nitrosococcus oceani (strain ATCC 19707
/ NCIMB 11848)
Length = 398
Score = 162 bits (393), Expect = 9e-39
Identities = 82/208 (39%), Positives = 131/208 (62%), Gaps = 3/208 (1%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTD--FTNIEKVKNAMQ-EN 173
++ L+ L GDHI+S ++YGGT + R+G + T+ + ++E +A +
Sbjct: 94 SSLLLHLAQPGDHIISVREIYGGTYAFFEGQLKRMGCSITYFNPAAPDLEAELDAQYTSH 153
Query: 174 TKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSL 353
++++++ETP+NP L +VD+EA + A RG ++ VVDNTF TPYLQ+PL+FG D ++S
Sbjct: 154 SRVLYLETPSNPSLALVDLEACSRWAHKRG-LVTVVDNTFCTPYLQRPLNFGIDWSVHST 212
Query: 354 TKYMNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHK 533
TKY+NGH D + G I + AI + +Q G V SP + + R L+TL+LRM H
Sbjct: 213 TKYLNGHGDCVGGVVIGTEPAIQALRQEVQWHFGNVLSPFNAWLTLRGLQTLSLRMARHS 272
Query: 534 KSSLIIANWLEKHPKIVEVLHPXLXTHP 617
+++L +A +LE+HPK+ V +P L +HP
Sbjct: 273 ETALTVARFLEEHPKVQRVHYPGLPSHP 300
>UniRef50_Q8KNG3 Cluster: CalE6; n=2; Micromonosporaceae|Rep: CalE6
- Micromonospora echinospora (Micromonospora purpurea)
Length = 381
Score = 160 bits (389), Expect = 3e-38
Identities = 83/210 (39%), Positives = 123/210 (58%), Gaps = 1/210 (0%)
Frame = +3
Query: 9 TLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQE-NTKMI 185
TL++L+ G +VS+DDVY GT+ L + +R G+ + D T E + A+ E + ++
Sbjct: 82 TLLSLVRPGQCVVSTDDVYAGTDGLF-DLAARQGVRVRYADLTTPEGIAAALAEPDLALV 140
Query: 186 WIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYM 365
WIETPTNPLL VVD+ + + A RG VVVDNTF +P LQ+PL GAD+ +YS TK +
Sbjct: 141 WIETPTNPLLTVVDVAEVSRRAHERG-ARVVVDNTFASPVLQQPLALGADVSLYSTTKSI 199
Query: 366 NGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSL 545
GH+DV+ GA + D + +R + G VP +DC+ V R L TL+LR+ ++
Sbjct: 200 AGHADVLGGALVYRDADLHAAVRAYRTTAGNVPGALDCFLVRRGLHTLSLRVHRQVATAR 259
Query: 546 IIANWLEKHPKIVEVLHPXLXTHPHTXXLK 635
++ L P + V +P L HP +K
Sbjct: 260 VLVERLRASPVVGAVHYPGLPEHPQHAVVK 289
>UniRef50_Q28Q09 Cluster: Cystathionine gamma-synthase; n=7;
Rhodobacterales|Rep: Cystathionine gamma-synthase -
Jannaschia sp. (strain CCS1)
Length = 396
Score = 160 bits (388), Expect = 3e-38
Identities = 80/208 (38%), Positives = 127/208 (61%), Gaps = 3/208 (1%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
+ T++ LL GDHIV + +YG + RL+ Q + R GI T+ D T+++ ++ A++ TKM
Sbjct: 92 SATILGLLGQGDHIVGGNQLYGRSLRLMHQDLGRFGIATSVADPTDVDAMRAALRPETKM 151
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
I +E +NP L+V D+ I+ +AR G +I+ VDNTF TP +PL GADI ++S+TK
Sbjct: 152 ILVEVISNPTLRVADMAGIIALAREVG-VILAVDNTFTTPAAYRPLVEGADITIHSVTKL 210
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQN---AMGIVPSPIDCYFVNRSLKTLALRMEHHK 533
+ GHSDV +G D D++R + + +G+ P+P +C+ R L T LR E +
Sbjct: 211 LAGHSDVTLGYVAARD---ADQMRAIYDFAVTVGMTPAPNECWLAERGLYTFPLRFEKAQ 267
Query: 534 KSSLIIANWLEKHPKIVEVLHPXLXTHP 617
++ +A++L HPK+ VL+P HP
Sbjct: 268 ANAAGLADYLAAHPKVARVLYPGRDDHP 295
>UniRef50_Q0B7N7 Cluster: Cystathionine gamma-synthase; n=4;
Betaproteobacteria|Rep: Cystathionine gamma-synthase -
Burkholderia cepacia (strain ATCC 53795 / AMMD)
Length = 389
Score = 159 bits (385), Expect = 8e-38
Identities = 76/204 (37%), Positives = 124/204 (60%)
Frame = +3
Query: 6 TTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMI 185
T +++++ GDH+V Y T ++L ++ R G+ TF D T++ A++ NT++I
Sbjct: 89 TAILSVVKAGDHVVGQTRHYMSTTKMLDDMLRRFGVEVTFVDQTDVAAFDRAIRPNTRLI 148
Query: 186 WIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYM 365
+E+P NPLL V DI A+ +IAR+RG I+ + DNTF +P Q+P G DIV++S TKY+
Sbjct: 149 VLESPVNPLLLVTDIGAVTEIARARG-ILTLADNTFASPVNQQPHRLGVDIVVHSATKYL 207
Query: 366 NGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSL 545
GH D + G I + + +++ +G V SP+D + + R L+TL +R+E ++
Sbjct: 208 GGHHD-LTGGVICTSRVLAEQIWHTHITLGSVLSPMDAWLLLRGLRTLPMRVERINANAQ 266
Query: 546 IIANWLEKHPKIVEVLHPXLXTHP 617
+A +LE H KI V +P L +HP
Sbjct: 267 ALAEFLEAHAKIERVFYPGLRSHP 290
>UniRef50_Q2AGF7 Cluster: O-acetylhomoserine/O-acetylserine
sulfhydrylase; n=1; Halothermothrix orenii H 168|Rep:
O-acetylhomoserine/O-acetylserine sulfhydrylase -
Halothermothrix orenii H 168
Length = 397
Score = 158 bits (384), Expect = 1e-37
Identities = 83/206 (40%), Positives = 124/206 (60%), Gaps = 1/206 (0%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
T T++ L++ G+ +VSS +YGGT LL + + R G+ T F +I + A+ + T++
Sbjct: 96 TLTILTLVSQGEEVVSSSYIYGGTYHLLAESLPRYGVKTRFVKPDDINDWEQAITDKTRV 155
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
++E+P NP L +VDIEA+ +A G I VVVDNTF TPYL +PL GADIV++S TKY
Sbjct: 156 FYLESPGNPRLNIVDIEAVSSLAHQYG-ITVVVDNTFNTPYLSQPLKLGADIVVHSTTKY 214
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRF-LQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKS 539
+ GH + I G IV + K+R L G SP + + + L+TL+LRME H +
Sbjct: 215 IGGHGNSI-GGVIVGTRDFIHKVRTELYRDTGPAISPFNAWLFIQGLETLSLRMEKHCSN 273
Query: 540 SLIIANWLEKHPKIVEVLHPXLXTHP 617
++ +A WL ++ V +P L HP
Sbjct: 274 AMEVARWLSGDERVEWVTYPGLPDHP 299
>UniRef50_Q5QWY7 Cluster: Cystathionine gamma-synthase; n=5;
Proteobacteria|Rep: Cystathionine gamma-synthase -
Idiomarina loihiensis
Length = 383
Score = 157 bits (382), Expect = 2e-37
Identities = 83/202 (41%), Positives = 123/202 (60%), Gaps = 2/202 (0%)
Frame = +3
Query: 6 TTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTK-M 182
T + L GD +++ +Y + L+ G++ F D TN+ ++++A+ E +
Sbjct: 85 TAVFQALKPGDKVIAPKVMYWALRKWLQTFGVDSGLDVRFVDTTNLNELRDAIAERQPTL 144
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
IW+ETP NPL V DI A+ +AR+ G ++ + D+T TP L KPLD GADIVM+S TKY
Sbjct: 145 IWLETPGNPLWTVTDIAAVADMARNCGSLLAI-DSTVATPLLTKPLDLGADIVMHSATKY 203
Query: 363 MNGHSDVIMGA-AIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKS 539
+NGHSDVI GA A D A +L ++ G VP P D + R ++TL LR+ +S
Sbjct: 204 LNGHSDVISGALAAREDNAFWQRLVAIRAQSGAVPGPQDAAQLLRGMRTLFLRVRESCQS 263
Query: 540 SLIIANWLEKHPKIVEVLHPXL 605
+L IA LE+HP+++EVL+P L
Sbjct: 264 ALYIAEQLEQHPQVIEVLYPGL 285
>UniRef50_Q5GSE3 Cluster: Cystathionine beta-lyase; n=5;
Wolbachia|Rep: Cystathionine beta-lyase - Wolbachia sp.
subsp. Brugia malayi (strain TRS)
Length = 413
Score = 157 bits (380), Expect = 3e-37
Identities = 77/205 (37%), Positives = 119/205 (58%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
T ++ G H++ D+ Y R + + + TF D T + + + +Q NT++
Sbjct: 97 TFAILTFARAGSHVLIQDNSYYRLRRFAENELPKRRVEVTFYDPT--QDIASLIQSNTRL 154
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
I IETP + +V +IE IVKIA+ I+ V DN++ TP L +PLD+G D+ +Y +TKY
Sbjct: 155 IMIETPGSVTFEVSNIEHIVKIAKEH-KIVTVCDNSWATPLLFRPLDYGIDVALYGVTKY 213
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
+ GHSD++MGA I + +N G+ P DCY +R L+TL RM H+ ++
Sbjct: 214 IAGHSDLLMGAIIAEGEVFKLLYEICKN-YGVTVQPYDCYLAHRGLRTLGTRMRKHQSTA 272
Query: 543 LIIANWLEKHPKIVEVLHPXLXTHP 617
+ +A WLEKH KI +VL+P L +HP
Sbjct: 273 MKVAKWLEKHSKIKKVLYPALPSHP 297
>UniRef50_A0NJV2 Cluster: O-succinylhomoserine thiol-lyase; n=2;
Leuconostocaceae|Rep: O-succinylhomoserine thiol-lyase -
Oenococcus oeni ATCC BAA-1163
Length = 369
Score = 157 bits (380), Expect = 3e-37
Identities = 73/195 (37%), Positives = 120/195 (61%), Gaps = 1/195 (0%)
Frame = +3
Query: 24 LNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWIETPT 203
L GD+ ++SDD+YGG+ R +V + GI+ + D T+ +K + T++IW+ETP+
Sbjct: 88 LKKGDNFIASDDLYGGSFRYFDDLVEKNGIDYSLWDGTDFSYLKQKISPKTRLIWLETPS 147
Query: 204 NPLLKVVDIEAIVK-IARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNGHSD 380
NP +K++DI+ + + + I+V VDNTFL+P LQ P+ GAD+V++S TKY+ GH+D
Sbjct: 148 NPTMKIIDIKKVADFVHKIDSKILVAVDNTFLSPILQNPIKLGADLVVHSATKYLGGHND 207
Query: 381 VIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLIIANW 560
++ G + + + L+ G V P C+ + RSLKTL+LR++ H S+ IA
Sbjct: 208 ILAGVVVSSRSELSKSLQENLITRGQVLDPFSCWLLLRSLKTLSLRVQRHSSSAQYIAKV 267
Query: 561 LEKHPKIVEVLHPXL 605
L K + ++L+P L
Sbjct: 268 LTKINGVDKILYPGL 282
>UniRef50_P13254 Cluster: Methionine gamma-lyase; n=33; cellular
organisms|Rep: Methionine gamma-lyase - Pseudomonas
putida
Length = 398
Score = 157 bits (380), Expect = 3e-37
Identities = 77/207 (37%), Positives = 126/207 (60%), Gaps = 2/207 (0%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
T+TL LL GD ++ + +YG T L + G+ D +++ ++ AM T++
Sbjct: 94 TSTLWTLLRPGDEVLLGNTLYGCTFAFLHHGIGEFGVKLRHVDMADLQALEAAMTPATRV 153
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
I+ E+P NP + + DI + KIAR G VVVDNT+ TPYLQ+PL+ GAD+V++S TKY
Sbjct: 154 IYFESPANPNMHMADIAGVAKIARKHG-ATVVVDNTYCTPYLQRPLELGADLVVHSATKY 212
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRF--LQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKK 536
++GH D+ G +V +A+ D++R L++ G V SP D + R +KTL LRM+ H
Sbjct: 213 LSGHGDITAG-IVVGSQALVDRIRLQGLKDMTGAVLSPHDAALLMRGIKTLNLRMDRHCA 271
Query: 537 SSLIIANWLEKHPKIVEVLHPXLXTHP 617
++ ++A +L + P++ + +P L + P
Sbjct: 272 NAQVLAEFLARQPQVELIHYPGLASFP 298
>UniRef50_A2BL10 Cluster: Methionine gamma-lyase; n=1; Hyperthermus
butylicus DSM 5456|Rep: Methionine gamma-lyase -
Hyperthermus butylicus (strain DSM 5456 / JCM 9403)
Length = 397
Score = 156 bits (379), Expect = 4e-37
Identities = 83/205 (40%), Positives = 123/205 (60%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
+T L ALL GD +V++ + YG T LL+++ R G+ + + A + TK+
Sbjct: 94 STLLFALLGPGDRVVATREAYGSTLHLLKEL-ERWGVKVVLAGPDSGDIASEASKPGTKL 152
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
+++ET TNPLL V D+ + K AR G I+VV DNTF TP L +PL GA +V++SLTKY
Sbjct: 153 VFVETITNPLLHVTDVPEVAKAARESGAILVV-DNTFATPILFRPLRHGATLVVHSLTKY 211
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
M GH+DV+ G+ + D+L + MG P + V R LKTL +R++ H +++
Sbjct: 212 MAGHNDVMGGSVTGPASIVSDRLWEWRKIMGTTMDPEQAFLVARGLKTLEIRVKRHCENA 271
Query: 543 LIIANWLEKHPKIVEVLHPXLXTHP 617
L IA +L +HPKI EV +P L +P
Sbjct: 272 LKIAEFLAEHPKIREVYYPGLPGNP 296
>UniRef50_Q5NPR0 Cluster: Cystathionine beta-lyases; n=5;
Sphingomonadales|Rep: Cystathionine beta-lyases -
Zymomonas mobilis
Length = 402
Score = 156 bits (378), Expect = 6e-37
Identities = 83/206 (40%), Positives = 127/206 (61%), Gaps = 1/206 (0%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
T+ L++ L+ GDH V +G L ++ R GI T D ++++ K+A+Q NTK+
Sbjct: 100 TSVLLSALSAGDHFVIGRVAFGSCRWLSDSLLPRFGITATVVDGADVQQWKDAIQPNTKL 159
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
+ ETPTNP L++VDIEA+ IA+ G I+ VVDN F TP +QKP+DFG D+V YS TK
Sbjct: 160 FFFETPTNPTLELVDIEAVCNIAKEAG-ILTVVDNAFCTPVIQKPMDFGVDVVAYSATKM 218
Query: 363 MNGHSDVIMGAAIVNDKAIGDK-LRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKS 539
M+G V+ G+ ++K + + L F++N G SP + + V + L+TL LR ++
Sbjct: 219 MDGQGRVLAGSVAGSNKFVNETLLPFIRNT-GPNLSPFNAWVVMKGLETLELRSIRQSEN 277
Query: 540 SLIIANWLEKHPKIVEVLHPXLXTHP 617
+ I+A +LEK +I V +P L +HP
Sbjct: 278 AQILAEFLEK--RIPRVSYPGLKSHP 301
>UniRef50_Q1IQ69 Cluster: Cystathionine beta-lyase; n=6;
Bacteria|Rep: Cystathionine beta-lyase - Acidobacteria
bacterium (strain Ellin345)
Length = 407
Score = 156 bits (378), Expect = 6e-37
Identities = 76/201 (37%), Positives = 119/201 (59%)
Frame = +3
Query: 15 VALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWIE 194
++LLN GDHI+ +++YG +L V+ R G+ T + +++NT+++W E
Sbjct: 114 LSLLNAGDHILIPENIYGPNRKLAYSVLKRFGVEVTVYPPLIGAGIAELIKDNTRLVWCE 173
Query: 195 TPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNGH 374
+P + ++V D+ AI K A +RG +VV+DNT+ + + D G D+ M +LTKY+ GH
Sbjct: 174 SPGSLTMEVQDVPAIAKAAHARG-ALVVLDNTWSSGIFFRAFDHGVDVEMQALTKYVAGH 232
Query: 375 SDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLIIA 554
SDV++GA + D+AI +KL +G PSP DC R +KTL +R+ S+L +A
Sbjct: 233 SDVLLGAITIRDRAIYEKLGNTYQVLGCAPSPDDCQLALRGMKTLGVRLAQIGSSALRVA 292
Query: 555 NWLEKHPKIVEVLHPXLXTHP 617
WL P+I VLHP L + P
Sbjct: 293 QWLAARPEIETVLHPALPSCP 313
>UniRef50_Q97CC7 Cluster: Cystathionine beta lyase /
O-succinylhomoserine lyase; n=5; Thermoplasmatales|Rep:
Cystathionine beta lyase / O-succinylhomoserine lyase -
Thermoplasma volcanium
Length = 394
Score = 156 bits (378), Expect = 6e-37
Identities = 86/201 (42%), Positives = 123/201 (61%), Gaps = 2/201 (0%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTF--TDFTNIEKVKNAMQENT 176
T+ ++AL GD I+S D+YG T L +V+ GI+ + TD N + K + +
Sbjct: 99 TSVILALAERGDKILSVSDLYGQTFYFLNKVLPEYGISVEYISTDRLNSGEFKPSDYD-- 156
Query: 177 KMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLT 356
+I++E+ TNP LKV DI+A+ + RS G I+V D TF +PY Q PLD GAD+V++S T
Sbjct: 157 -IIYLESITNPTLKVPDIKAVSE--RSTGKKIIV-DATFASPYNQNPLDLGADVVIHSAT 212
Query: 357 KYMNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKK 536
KY++GHSDV+MG NDK+I DK+ + G P PI Y R +KTL LRME H K
Sbjct: 213 KYISGHSDVVMGVFSTNDKSIFDKVVVRRKTFGSNPDPIQSYLALRGIKTLGLRMEKHNK 272
Query: 537 SSLIIANWLEKHPKIVEVLHP 599
+ + +A +L P+I V +P
Sbjct: 273 NGMELAKYLRTEPRISHVYYP 293
>UniRef50_A4AND2 Cluster: Cystathionine gamma-lyase; n=2; cellular
organisms|Rep: Cystathionine gamma-lyase -
Flavobacteriales bacterium HTCC2170
Length = 396
Score = 155 bits (376), Expect = 1e-36
Identities = 76/206 (36%), Positives = 127/206 (61%), Gaps = 1/206 (0%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSR-LGINTTFTDFTNIEKVKNAMQENTK 179
T + + L DH+V+ ++YG + LL+ +S+ + I TTF +IE ++A++ENT
Sbjct: 91 TASCLHFLRPNDHVVAIKNLYGPASNLLKSYLSKKMNIETTFVSGEHIEDFEDAIRENTA 150
Query: 180 MIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTK 359
+I++E+P+ + + DIEAI +ARS+G I ++DNT TP QKPLD G D+ ++S TK
Sbjct: 151 LIYLESPSTAVFSLQDIEAIANLARSKG-IKTMIDNTLATPIFQKPLDMGIDLEVHSFTK 209
Query: 360 YMNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKS 539
Y+ GHSD+I G I K + +G +P++ + + RSL+TL +R++ H+ +
Sbjct: 210 YLGGHSDLIGGVVIGAQKEVDSIFHNEYELLGAKTAPMEAWLLLRSLRTLTMRVKRHQSN 269
Query: 540 SLIIANWLEKHPKIVEVLHPXLXTHP 617
++ IA +LE H +I V +P L + P
Sbjct: 270 AMAIAEFLEGHSQIEFVRYPGLNSFP 295
>UniRef50_Q1VZU8 Cluster: Cystathionine beta-lyase; n=12;
Bacteroidetes|Rep: Cystathionine beta-lyase -
Psychroflexus torquis ATCC 700755
Length = 405
Score = 155 bits (375), Expect = 1e-36
Identities = 73/212 (34%), Positives = 132/212 (62%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
TT ++++L GDH++ + +YGGT + + R GI+ F D N+ +++ ++ TK+
Sbjct: 104 TTAMLSVLESGDHVILQNQIYGGTRNFIIEECHRYGISFDFIDVNNLTLLESTVKPETKL 163
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
++IETP+NPLL++ D++ + K A+ +G I+ + DNTF +P Q+PLD G DIV++S TKY
Sbjct: 164 LYIETPSNPLLEITDLKLVSKFAKEKG-ILTMADNTFASPINQRPLDLGIDIVLHSATKY 222
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
+ GHSD+ G A+ + +AI +K+ G + + + RS+KTL LR++ +++
Sbjct: 223 LGGHSDITAG-AVASTEAIMNKVFSKAKNFGGSLADQTVWLLERSMKTLNLRVKQQTQNA 281
Query: 543 LIIANWLEKHPKIVEVLHPXLXTHPHTXXLKN 638
+ +A +LE + +V +P L ++P K+
Sbjct: 282 MDMAEFLENSSFVDKVYYPGLESNPQHQLAKD 313
>UniRef50_Q5QU17 Cluster: Methionine gamma-lyase; n=29; cellular
organisms|Rep: Methionine gamma-lyase - Idiomarina
loihiensis
Length = 408
Score = 154 bits (373), Expect = 2e-36
Identities = 77/200 (38%), Positives = 117/200 (58%)
Frame = +3
Query: 15 VALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWIE 194
+A + GDHIV SD +YG + L ++ R G+ F D N +K ++ENT+++++E
Sbjct: 102 MAFVRSGDHIVVSDAIYGCSFALFSELFERFGVEADFIDLNNEGLLKETLRENTRLVFLE 161
Query: 195 TPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNGH 374
TP NP LKVVDIE + + DI +VVDNTF+TP +Q+P GADIV++S TK++NGH
Sbjct: 162 TPANPHLKVVDIEKVHAVIAD-SDIRLVVDNTFMTPLMQQPKRHGADIVVHSATKFLNGH 220
Query: 375 SDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLIIA 554
DV+ G +D I MG SP D + + R LKTL +RM+ H +++ +
Sbjct: 221 GDVVAGIICGSDDDINTIKSTTLKDMGATISPHDAWLILRGLKTLDVRMQRHCENADAVY 280
Query: 555 NWLEKHPKIVEVLHPXLXTH 614
++L I ++ +P H
Sbjct: 281 DFLAARQDIKKIYYPGAPDH 300
>UniRef50_A4FF27 Cluster: Methionine gamma-lyase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep: Methionine
gamma-lyase - Saccharopolyspora erythraea (strain NRRL
23338)
Length = 396
Score = 154 bits (373), Expect = 2e-36
Identities = 70/205 (34%), Positives = 122/205 (59%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
+T L+ L+ GDH+++ +YG T LL + R G+ T ++E+++ A++ NTK+
Sbjct: 91 STVLLGSLSSGDHVIAQRGLYGATLALLADLAQRWGVEVTHASGHDVEEMRAALRPNTKL 150
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
+++ET NP ++ D+ + +AR G ++ VVDNTF TP L +P++ GAD+V++S TKY
Sbjct: 151 LYLETIGNPTTRIADLPGLFAVAREHG-VMSVVDNTFATPVLCRPIEHGADVVVHSTTKY 209
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
+ GH D + G A+ D+ ++R +G +PI + R L+TL+LR++ ++
Sbjct: 210 IGGHGDTLGGIAVFADRERHRRIRDYSCQLGATAAPIPAWLALRGLRTLSLRVQRQCDNA 269
Query: 543 LIIANWLEKHPKIVEVLHPXLXTHP 617
++A L P + V HP L +HP
Sbjct: 270 KLLAERLSADPAVTAVHHPSLESHP 294
>UniRef50_A0LY60 Cluster: O-succinylhomoserine sulfhydrylase; n=13;
Bacteria|Rep: O-succinylhomoserine sulfhydrylase -
Gramella forsetii (strain KT0803)
Length = 404
Score = 153 bits (371), Expect = 4e-36
Identities = 73/204 (35%), Positives = 133/204 (65%)
Frame = +3
Query: 6 TTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMI 185
+TL ALLN GDHIVS+ V+G T+ L + + I+ ++ D E +++ ++ TK++
Sbjct: 106 STLAALLNSGDHIVSARSVFGSTHGLFTRYFPKWNISHSYFDVNKPETIEDLIKPETKIL 165
Query: 186 WIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYM 365
+ E+PTNP + ++D+E + +IA+ + +I+++DN F TPY+Q P+ FGAD+V++S TK +
Sbjct: 166 FAESPTNPGVDILDLEFLGQIAK-KHHLILIIDNCFATPYIQNPIKFGADLVIHSATKLI 224
Query: 366 NGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSL 545
+G V+ G + + I + F +N G SP + + +++SL+TLA+R++ H +++L
Sbjct: 225 DGQGRVLGGVTVGREDLIREIYLFSRNT-GPALSPFNAWVLSKSLETLAVRLDRHCENAL 283
Query: 546 IIANWLEKHPKIVEVLHPXLXTHP 617
+A +LE + I +V +P L +HP
Sbjct: 284 KVAEFLEANKNIEQVKYPFLKSHP 307
>UniRef50_P00935 Cluster: Cystathionine gamma-synthase (EC 2.5.1.48)
(CGS) (O-succinylhomoserine (thiol)-lyase); n=123;
Proteobacteria|Rep: Cystathionine gamma-synthase (EC
2.5.1.48) (CGS) (O-succinylhomoserine (thiol)-lyase) -
Escherichia coli (strain K12)
Length = 386
Score = 153 bits (371), Expect = 4e-36
Identities = 77/194 (39%), Positives = 116/194 (59%)
Frame = +3
Query: 24 LNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWIETPT 203
L GD +V+ D YGG+ RL + R F D + + ++ A+ E K++ +E+P+
Sbjct: 88 LKPGDLLVAPHDCYGGSYRLFDSLAKRGCYRVLFVDQGDEQALRAALAEKPKLVLVESPS 147
Query: 204 NPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNGHSDV 383
NPLL+VVDI I +AR G + VVDNTFL+P LQ PL GAD+V++S TKY+NGHSDV
Sbjct: 148 NPLLRVVDIAKICHLAREVG-AVSVVDNTFLSPALQNPLALGADLVLHSCTKYLNGHSDV 206
Query: 384 IMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLIIANWL 563
+ G I D + +L + N +G+ D Y + R L+TL RME ++++ I +L
Sbjct: 207 VAGVVIAKDPDVVTELAWWANNIGVTGGAFDSYLLLRGLRTLVPRMELAQRNAQAIVKYL 266
Query: 564 EKHPKIVEVLHPXL 605
+ P + ++ HP L
Sbjct: 267 QTQPLVKKLYHPSL 280
>UniRef50_Q8G805 Cluster: Cystathionine beta-lyase; n=2;
Bifidobacterium longum|Rep: Cystathionine beta-lyase -
Bifidobacterium longum
Length = 412
Score = 151 bits (367), Expect = 1e-35
Identities = 80/205 (39%), Positives = 126/205 (61%), Gaps = 7/205 (3%)
Frame = +3
Query: 12 LVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQEN------ 173
++++ GD IV D++YGG+ L + +R GI D +I ++ A++ +
Sbjct: 82 VLSIFKPGDRIVVGDNIYGGSYSQLNEFFTRWGILVEAVDTQDIAALEAAVKGDRANGIV 141
Query: 174 -TKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYS 350
+ ++ ET TNPLLKV D+ AI +A G + +VDNTF+TPYLQKPL GAD+V++S
Sbjct: 142 PAQAVYFETLTNPLLKVNDVRAISTVAHRFG-ALSIVDNTFVTPYLQKPLALGADVVIHS 200
Query: 351 LTKYMNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHH 530
TKY+ GHSDV G +V+ + + ++ F QN +G V +P +C V R ++TLALRM+
Sbjct: 201 ATKYLAGHSDVNAGLVVVSGEDLASRVYFAQNRLGGVLAPAECDAVRRGIQTLALRMDRQ 260
Query: 531 KKSSLIIANWLEKHPKIVEVLHPXL 605
++++ IA +L HP + V +P L
Sbjct: 261 QENANAIARYLLVHPLVKAVHYPGL 285
>UniRef50_Q399B4 Cluster: Cystathionine beta-lyase; n=15;
Proteobacteria|Rep: Cystathionine beta-lyase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 393
Score = 151 bits (367), Expect = 1e-35
Identities = 72/199 (36%), Positives = 125/199 (62%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
TT L+A+LN GDH++ +D VY T + ++RLGI TT+ D T + + M+ NT+
Sbjct: 88 TTALLAVLNPGDHLLMADSVYDPTRSFCDETLARLGIETTYFDPTIGADIASLMRPNTRA 147
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
++ E+P + +V DI AI ++A RG +V++DNT+ TP + G D+ +++ TKY
Sbjct: 148 VFAESPGSLTFEVQDIPAISRVAHQRG-AVVLLDNTWGTPLNFRSFSHGVDVSIHAATKY 206
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
+ GHSDV+MG AI+ +A+ K+ +G+ S D Y R L+TL++R+E H++++
Sbjct: 207 IAGHSDVLMG-AILTTEALAPKVTRFYRQLGMTVSGDDAYLALRGLRTLSVRLERHQRNA 265
Query: 543 LIIANWLEKHPKIVEVLHP 599
++ +WL + P++ +L+P
Sbjct: 266 HVLTDWLSQQPEVARILYP 284
>UniRef50_A5WG79 Cluster: O-succinylhomoserine sulfhydrylase; n=6;
Proteobacteria|Rep: O-succinylhomoserine sulfhydrylase -
Psychrobacter sp. PRwf-1
Length = 434
Score = 151 bits (367), Expect = 1e-35
Identities = 75/204 (36%), Positives = 129/204 (63%)
Frame = +3
Query: 6 TTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMI 185
T +A L GDHIV++ ++G T L + + G++ T+ D + + +A++ NT+++
Sbjct: 125 TMCLAYLKQGDHIVAAKQLFGSTVGLFNNFMGKFGVSVTYVDCFDNQAWADAIEPNTRLL 184
Query: 186 WIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYM 365
+ ETP+NPL ++ D++AI +IA ++G + VVDN F TP +QKPLDFGAD+V++S TKY+
Sbjct: 185 FCETPSNPLGQIADLQAISEIAHAQG-ALFVVDNCFATPAIQKPLDFGADVVIHSATKYI 243
Query: 366 NGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSL 545
+G V+ GA + +D+ + +++ GI SP + + + L+TL LRM+ H ++
Sbjct: 244 DGQGRVLGGALVGSDELMQQAFVVVRSG-GISMSPFNAWVFIKGLETLNLRMQAHCDNAN 302
Query: 546 IIANWLEKHPKIVEVLHPXLXTHP 617
IA +L+ HP + +V L +HP
Sbjct: 303 KIAAFLQSHPHVEKVHFSGLTSHP 326
>UniRef50_Q4QFT8 Cluster: Cystathionine beta-lyase-like protein;
n=4; Eukaryota|Rep: Cystathionine beta-lyase-like
protein - Leishmania major
Length = 459
Score = 151 bits (367), Expect = 1e-35
Identities = 74/198 (37%), Positives = 123/198 (62%), Gaps = 2/198 (1%)
Frame = +3
Query: 9 TLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQEN--TKM 182
TLV LN GD I++S D+YGG +RLL Q+ S LG+ F + E V+ A+ +N K+
Sbjct: 140 TLVTTLNAGDTILASSDLYGGMHRLLTQITSCLGMTVVFVPMWDTEAVRQALVDNPAAKL 199
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
+ +E+PTNPL+++VDI A+ + A + ++ V +DNT ++P PL G D ++S TK+
Sbjct: 200 LHMESPTNPLMRIVDIRAVCEAAHAH-NVKVSIDNTMMSPLRCTPLALGCDYSIHSATKF 258
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
+ GHSD + G V + ++ FLQNA G +P DC+ + R ++TL++R+E + ++
Sbjct: 259 LCGHSDTMCGLICVKSEEDVKRVAFLQNAQGNALAPFDCWLLLRGIRTLSIRVEKQELNA 318
Query: 543 LIIANWLEKHPKIVEVLH 596
+ +A +L + +V LH
Sbjct: 319 VAVALFLSRQSHVVSRLH 336
>UniRef50_A6PIC3 Cluster: Cystathionine beta-lyase; n=1; Shewanella
sediminis HAW-EB3|Rep: Cystathionine beta-lyase -
Shewanella sediminis HAW-EB3
Length = 411
Score = 150 bits (364), Expect = 3e-35
Identities = 75/202 (37%), Positives = 121/202 (59%)
Frame = +3
Query: 12 LVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWI 191
L++ L GDH++ D Y T L ++++ GI TT+ D + ++ NTK++++
Sbjct: 109 LLSFLKAGDHLLMVDSAYEPTRDLCNKLLAGFGIETTYYDPMIGAGISELIRPNTKVLFL 168
Query: 192 ETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNG 371
E+P + ++V D+ + +IA DI+V++DNT+ +P +P D G DI + + TKY+ G
Sbjct: 169 ESPGSITMEVQDVPTLSEIAHKH-DIVVMLDNTWASPINSRPFDMGVDISIQAATKYIVG 227
Query: 372 HSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLII 551
HSDV+MG A N+ A D+LR MG SP D Y NR L+TL +RM+ H++++L +
Sbjct: 228 HSDVMMGTATSNE-AHWDQLRENSYLMGQCTSPDDVYLANRGLRTLGVRMQQHEQNALKV 286
Query: 552 ANWLEKHPKIVEVLHPXLXTHP 617
ANWL P++ + HP T P
Sbjct: 287 ANWLATRPEVDHIRHPAFDTCP 308
>UniRef50_Q49UL3 Cluster: Cystathionine beta-lyase cystathionine
gamma-synthase; n=14; Staphylococcus|Rep: Cystathionine
beta-lyase cystathionine gamma-synthase - Staphylococcus
saprophyticus subsp. saprophyticus (strain ATCC 15305
/DSM 20229)
Length = 367
Score = 150 bits (363), Expect = 4e-35
Identities = 74/192 (38%), Positives = 119/192 (61%)
Frame = +3
Query: 21 LLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWIETP 200
L GD I+ S D+YGGT RL + GI+ + DF N E+V+ ++ E+TK ++IE
Sbjct: 82 LFKSGDEILVSFDLYGGTFRLFDFYEQQYGIHFKYVDFLNYEEVEQSITEHTKALFIEPI 141
Query: 201 TNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNGHSD 380
+NP + VD++ +++ + +++ ++DNTFLTPYL PL+ GADIV++S TKY+ GH+D
Sbjct: 142 SNPQMIEVDVDPFYILSK-KFNLLTIIDNTFLTPYLSTPLEDGADIVLHSATKYIGGHND 200
Query: 381 VIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLIIANW 560
V+ G V D + ++L L N +G SP D Y + R LKTL LRM+ + ++ +++
Sbjct: 201 VLAGVVTVKDNQLAEQLGQLHNMIGATLSPFDSYLLQRGLKTLHLRMDRSEYNAKLLSER 260
Query: 561 LEKHPKIVEVLH 596
I +VL+
Sbjct: 261 CSDLEAIDKVLY 272
>UniRef50_Q1GNK9 Cluster: Cystathionine beta-lyase; n=4;
Sphingomonadales|Rep: Cystathionine beta-lyase -
Sphingopyxis alaskensis (Sphingomonas alaskensis)
Length = 400
Score = 150 bits (363), Expect = 4e-35
Identities = 75/198 (37%), Positives = 120/198 (60%)
Frame = +3
Query: 12 LVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWI 191
L+ALL+ GDH++ D Y T +++RLG+ TT+ D + ++ T++I++
Sbjct: 104 LLALLSPGDHLLMVDSAYEPTRAFCDGMLARLGVTTTYYDPLVGAAIAELIRPETRLIFL 163
Query: 192 ETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNG 371
E+P + +V D+ AI +AR+RG ++ ++DNT+ TP L L G D+ M SLTKY+ G
Sbjct: 164 ESPGSLTFEVQDVPAITGVARARG-VLTMIDNTWATPLLFPALAHGVDVAMMSLTKYVGG 222
Query: 372 HSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLII 551
HSD +MG ++ +A+ KLR +G SP DC + R L+TL +RM+ H ++ L++
Sbjct: 223 HSDAMMG-SLTATRAVWPKLRSAAYQLGQAVSPDDCALMLRGLRTLDVRMQRHGENGLVV 281
Query: 552 ANWLEKHPKIVEVLHPXL 605
ANWL ++ VLHP L
Sbjct: 282 ANWLAARGEVGRVLHPAL 299
>UniRef50_A6W1L9 Cluster: Cystathionine gamma-synthase; n=10;
Bacteria|Rep: Cystathionine gamma-synthase - Marinomonas
sp. MWYL1
Length = 405
Score = 150 bits (363), Expect = 4e-35
Identities = 71/206 (34%), Positives = 124/206 (60%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
++ L L++G +VS+ D YGGTN++ + + R+G++ T + + E++++ + + +
Sbjct: 99 SSVLYTFLSNGCRVVSTKDSYGGTNKVFEEFLPRMGVSVTLCETHSHEQIEDEIAKGCDV 158
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
+++ETPTNP LK+VD++ +V A+ G +V+ DNTF TP Q PL G DIV++S TK+
Sbjct: 159 LYLETPTNPTLKIVDVKRLVAAAKKVG-ALVMADNTFATPLNQSPLALGVDIVVHSATKF 217
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
++GH+D MG + + + K+R + G P Y + R +KTLALR+ + S+
Sbjct: 218 LSGHADA-MGGLVCGSEELMAKVRHYREINGASLDPFSAYLIIRGMKTLALRIRQQQSSA 276
Query: 543 LIIANWLEKHPKIVEVLHPXLXTHPH 620
IA +L + V +P L +HP+
Sbjct: 277 KAIAEYLLTETLVEAVNYPGLPSHPN 302
>UniRef50_A1ZIW0 Cluster: Cys/Met metabolism
pyridoxal-phosphate-dependent enzymes; n=1; Microscilla
marina ATCC 23134|Rep: Cys/Met metabolism
pyridoxal-phosphate-dependent enzymes - Microscilla
marina ATCC 23134
Length = 391
Score = 150 bits (363), Expect = 4e-35
Identities = 68/203 (33%), Positives = 129/203 (63%), Gaps = 1/203 (0%)
Frame = +3
Query: 12 LVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWI 191
++A +N GDH+V Y TN+LL ++R G+ T D T+ + ++A+Q NT+++++
Sbjct: 90 VIANVNQGDHVVCVQKPYSWTNKLLNSFLNRFGVTNTMVDGTDPQNFESAIQPNTRVLFL 149
Query: 192 ETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNG 371
E+P + + D+ A+ +IA+ + DI+ ++DN++ TP QKP+D+G DIV++S TKY++G
Sbjct: 150 ESPNSWTFEQQDLAAVAQIAK-KHDIVTIIDNSYATPLFQKPIDYGIDIVVHSATKYISG 208
Query: 372 HSDVIMGAAIVNDKAIGDKLRFLQ-NAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLI 548
HSD + G + KA+ +K+ + +G V +P + + + R L+TL RM+ ++ I
Sbjct: 209 HSDTVAG-VLCASKAMTNKIFASEYMTLGGVVAPFNAWLLLRGLRTLPTRMDRVSATTAI 267
Query: 549 IANWLEKHPKIVEVLHPXLXTHP 617
+ N+L++H + ++ +P L + P
Sbjct: 268 VVNYLQEHSMVSKIYYPYLESDP 290
>UniRef50_A1A0Q5 Cluster: Cystathionine beta-lyase; n=2;
Bifidobacterium adolescentis|Rep: Cystathionine
beta-lyase - Bifidobacterium adolescentis (strain ATCC
15703 / DSM 20083)
Length = 411
Score = 150 bits (363), Expect = 4e-35
Identities = 83/213 (38%), Positives = 126/213 (59%), Gaps = 10/213 (4%)
Frame = +3
Query: 12 LVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGI---NTTFTDFTNI------EKVK-NA 161
++++ GD I+ ++YGGT L + R G+ TD+ + E K NA
Sbjct: 82 VLSIFQPGDRIIVGKNIYGGTYSLFHEYFERWGVIVEEVGTTDYKALDAAVSGESAKGNA 141
Query: 162 MQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIV 341
K ++ E TNPLL+V ++ AI IA G I +VDNTF+TPYLQ+PLD GADIV
Sbjct: 142 HGCPAKAVYFEVLTNPLLQVNNVTAIAGIAHRHG-AIAIVDNTFVTPYLQQPLDQGADIV 200
Query: 342 MYSLTKYMNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRM 521
++S TKY+ GHS+V G +V D +G ++ F QN +G V +P +C V R ++TLALRM
Sbjct: 201 IHSATKYLAGHSEVNAGLVVVKDDELGKRVYFAQNRLGGVLAPNECDSVRRGIQTLALRM 260
Query: 522 EHHKKSSLIIANWLEKHPKIVEVLHPXLXTHPH 620
+ ++++ I+++L HP + V +P L H +
Sbjct: 261 DRQQENARAISSYLLLHPLVKSVHYPGLPGHEY 293
>UniRef50_Q0ALD7 Cluster: Cystathionine gamma-synthase; n=2;
Hyphomonadaceae|Rep: Cystathionine gamma-synthase -
Maricaulis maris (strain MCS10)
Length = 382
Score = 149 bits (362), Expect = 5e-35
Identities = 74/196 (37%), Positives = 116/196 (59%)
Frame = +3
Query: 30 HGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNP 209
HG ++ S D YGGT RLL + + D T++EKV +A+ E+ +I ETP+NP
Sbjct: 89 HGARVICSHDAYGGTRRLLDARGRGGRLIPVYVDTTDLEKVADALNEDAALIIAETPSNP 148
Query: 210 LLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNGHSDVIM 389
L++ DI+ + ++AR+ G + V DNT ++P LQ+PLD+GAD + S+TK +NGHSD++
Sbjct: 149 RLRISDIKGLARLARNAGTELAV-DNTVMSPVLQRPLDWGADYSVQSVTKLLNGHSDMVG 207
Query: 390 GAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLIIANWLEK 569
G D +L + N +G+ + D Y R L+TL LR +S+ +A WL+
Sbjct: 208 GVVCCADPERVAELGWWANCVGVGAAAFDSYLALRGLRTLPLRARAQCESAQEVARWLDA 267
Query: 570 HPKIVEVLHPXLXTHP 617
P++ V +P L +HP
Sbjct: 268 DPRVARVDYPGLTSHP 283
>UniRef50_Q5PBE9 Cluster: Cystathionine beta-lyase; n=1; Anaplasma
marginale str. St. Maries|Rep: Cystathionine beta-lyase
- Anaplasma marginale (strain St. Maries)
Length = 408
Score = 149 bits (360), Expect = 9e-35
Identities = 79/206 (38%), Positives = 123/206 (59%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
T V + G HI+ Y +R +++ RLG + + + + E V E T +
Sbjct: 110 TMACVTFCDAGSHILVPKKAYFKLHRFIQESCPRLGRSVSV--YESAEDVPKMANEKTSL 167
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
I+IET ++ L + D+ I++ A+ RG I+V+ DN+ + P + P + GADIVMYSLTKY
Sbjct: 168 IFIETLSSSRLIIEDVSPIIEFAKKRG-IVVLCDNSCI-PTVFNPFNCGADIVMYSLTKY 225
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
GHSDV+MGA IVND+ I D+L GI S DCY V R +KT+ +RM+ + ++
Sbjct: 226 FGGHSDVMMGALIVNDEGIFDRLYVDHRNYGIYVSSDDCYLVQRGMKTMRVRMQQVQSTA 285
Query: 543 LIIANWLEKHPKIVEVLHPXLXTHPH 620
+ +A+ L+ H KI +V++P L ++PH
Sbjct: 286 IALASRLQAHKKISQVIYPGLPSYPH 311
>UniRef50_Q338K0 Cluster: Cys/Met metabolism PLP-dependent enzyme
family protein; n=7; Oryza sativa|Rep: Cys/Met
metabolism PLP-dependent enzyme family protein - Oryza
sativa subsp. japonica (Rice)
Length = 433
Score = 149 bits (360), Expect = 9e-35
Identities = 78/205 (38%), Positives = 124/205 (60%), Gaps = 2/205 (0%)
Frame = +3
Query: 9 TLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTN-IEKVKNAMQEN-TKM 182
TL+AL+ G H+V++ D Y +R +S +GI +TF D + +E +++ + E M
Sbjct: 172 TLLALVPPGGHVVATADCYSEARAFIRDKLSNMGITSTFVDLDDDMEALESVLDEGEVTM 231
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
+ ++ TNP LKVVD+ + ++ RG +V +D+T +P QKPL GAD+V++S TKY
Sbjct: 232 FYADSMTNPHLKVVDVTRVAELCHRRG-ALVCIDSTLASPINQKPLALGADVVLHSATKY 290
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
+ GH DVI G + +A+ ++R + +G SP Y + R LKTLALR++ +++
Sbjct: 291 IAGHHDVIAGC-VSGSEALVSRIRTWHHDLGGAISPNAAYMIIRGLKTLALRVQAQNRTA 349
Query: 543 LIIANWLEKHPKIVEVLHPXLXTHP 617
L +A LEKHPKI V +P L + P
Sbjct: 350 LRMAQLLEKHPKIERVYYPGLESSP 374
>UniRef50_Q11FS5 Cluster: Cystathionine beta-lyase; n=5;
Alphaproteobacteria|Rep: Cystathionine beta-lyase -
Mesorhizobium sp. (strain BNC1)
Length = 398
Score = 148 bits (359), Expect = 1e-34
Identities = 83/228 (36%), Positives = 128/228 (56%), Gaps = 1/228 (0%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
T TL +L+ GD ++ D VY + + R+G++ + D + + T++
Sbjct: 98 TMTLQTMLSPGDTVLLVDTVYPPVREFADRFLRRMGVDIVYYDPAIGAGIAELITATTRL 157
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
+W+E+P + ++V DI AIV AR+RG + +DNT+ TP L KPL+ G DIV+ +++KY
Sbjct: 158 VWMESPGSTTMEVQDIPAIVAAARARG-VPTAIDNTWATPLLLKPLELGVDIVIQAVSKY 216
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
M GHSD++MGA V D A+ D+LR +G SP DC V R L+TLA+R+ S+
Sbjct: 217 MAGHSDLLMGAVTVRDLALFDRLRTAFKLLGHGVSPDDCSLVLRGLETLAVRLRQSSASA 276
Query: 543 LIIANWLEKHPKIVEVLHPXLXTHP-HTXXLKNX*RVTRVCSVSNXPE 683
L +A LE+ + VLHP L + H ++ + V SV PE
Sbjct: 277 LDLARMLEESGRFQAVLHPALPSFSGHAIWKRDFKGASGVFSVVLKPE 324
>UniRef50_A7DB98 Cluster: Cystathionine gamma-synthase; n=2;
Methylobacterium extorquens PA1|Rep: Cystathionine
gamma-synthase - Methylobacterium extorquens PA1
Length = 405
Score = 148 bits (358), Expect = 1e-34
Identities = 80/200 (40%), Positives = 113/200 (56%), Gaps = 2/200 (1%)
Frame = +3
Query: 24 LNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQEN-TKMIWIETP 200
L GDH+++ + +Y G R LRQ RL + F + E V+ A++ T+++WIETP
Sbjct: 110 LERGDHVIAPEVMYWGLRRWLRQEAPRLDLAVDFVPMDDPEAVRAAIRPGKTRLVWIETP 169
Query: 201 TNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNGHSD 380
NPL V DI IV+IA + G V VD+T +P L +PL GA+IVM+S TK +NGHSD
Sbjct: 170 GNPLCTVADIARIVEIAHAAG-ARVAVDSTAASPILTRPLTLGAEIVMHSATKILNGHSD 228
Query: 381 VIMGA-AIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLIIAN 557
V+ G A A D+L ++ G + P + Y + R L+TL LR +L +A
Sbjct: 229 VVAGVLAGARKDAFWDRLVAIRGGWGAILGPFEAYLLMRGLRTLPLRAAAQSAGALHLAQ 288
Query: 558 WLEKHPKIVEVLHPXLXTHP 617
L HP + VL+P L HP
Sbjct: 289 RLSAHPLVRAVLYPGLPDHP 308
>UniRef50_A4AA77 Cluster: Cystathionine beta-lyase; n=2;
Bacteria|Rep: Cystathionine beta-lyase - Congregibacter
litoralis KT71
Length = 439
Score = 147 bits (357), Expect = 2e-34
Identities = 71/198 (35%), Positives = 117/198 (59%)
Frame = +3
Query: 24 LNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWIETPT 203
L+ GDH++ D VYG T + ++R G+ T+F D E +++ + ++T+MI++E+P
Sbjct: 141 LSPGDHLLMVDSVYGPTRKFCVGSLARRGVRTSFYDPLKHESLESLIDDSTRMIFMESPG 200
Query: 204 NPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNGHSDV 383
+ ++ D+ AIV +A+ G ++ +DNT+ TP L PLDFG D+ M S TKY+NGH+D
Sbjct: 201 SATFEIQDVPAIVAVAKQHG-LLTAIDNTWATPLLFNPLDFGVDLAMQSGTKYLNGHADC 259
Query: 384 IMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLIIANWL 563
+ G + + +L A G+ +P D R L+TLA+RM H + + +A WL
Sbjct: 260 LFGVTTMRSPELYTQLHHHTLAHGMHLAPDDANLALRGLRTLAVRMGVHDQGARCVAAWL 319
Query: 564 EKHPKIVEVLHPXLXTHP 617
EK P++ +LHP + P
Sbjct: 320 EKQPRVRRLLHPAWESCP 337
>UniRef50_Q1ELY9 Cluster: Cystathionine beta-lyases/cystathionine
gamma-synthases; n=1; uncultured Thermotogales
bacterium|Rep: Cystathionine beta-lyases/cystathionine
gamma-synthases - uncultured Thermotogales bacterium
Length = 380
Score = 147 bits (356), Expect = 3e-34
Identities = 79/201 (39%), Positives = 123/201 (61%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
TT + L G ++V S ++YGGT LL + +G+ D + +E +++ + +NT +
Sbjct: 82 TTIFLTFLRSGMNLVISRNIYGGTQSLLGDLPD-MGVEIRRFDQSRLEGLESLVDDNTGI 140
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
+++E+ TNP L + DI+ I I SR ++VVDNTFL+PY +PL++GADI + SL+KY
Sbjct: 141 VYVESMTNPNLILSDIQRISHIT-SRSRALLVVDNTFLSPYNFRPLEYGADIDVQSLSKY 199
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
+NGHSDVI G A ++ + + R +G +P + + V R +KTL LRME H ++
Sbjct: 200 VNGHSDVIAGFAAFRNRELETRARKKMIKLGTNGAPFEAFLVCRGVKTLGLRMELHNNNA 259
Query: 543 LIIANWLEKHPKIVEVLHPXL 605
IA +L K PK+ V HP L
Sbjct: 260 KEIALFLSKSPKVSLVSHPSL 280
>UniRef50_P55217 Cluster: Cystathionine gamma-synthase, chloroplast
precursor (EC 2.5.1.48) (CGS) (O-succinylhomoserine
(thiol)-lyase); n=30; Viridiplantae|Rep: Cystathionine
gamma-synthase, chloroplast precursor (EC 2.5.1.48)
(CGS) (O-succinylhomoserine (thiol)-lyase) - Arabidopsis
thaliana (Mouse-ear cress)
Length = 563
Score = 147 bits (356), Expect = 3e-34
Identities = 78/206 (37%), Positives = 119/206 (57%), Gaps = 1/206 (0%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQE-NTK 179
T L+AL+ G HIV++ D Y T + + +LGI T D +I ++ A+ E
Sbjct: 261 TVMLLALVPAGGHIVTTTDCYRKTRIFMENFLPKLGITVTVIDPADIAGLEAAVNEFKVS 320
Query: 180 MIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTK 359
+ + E+PTNP L+ VDIE + KI RG + V +D TF TP QK L GAD+V++S TK
Sbjct: 321 LFFTESPTNPFLRCVDIELVSKICHKRGTL-VCIDGTFATPLNQKALALGADLVVHSATK 379
Query: 360 YMNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKS 539
Y+ GH+DV+ G + K + + +R L + +G +P Y + R +KTL LR++ +
Sbjct: 380 YIGGHNDVLAGCICGSLKLVSE-IRNLHHVLGGTLNPNAAYLIIRGMKTLHLRVQQQNST 438
Query: 540 SLIIANWLEKHPKIVEVLHPXLXTHP 617
+ +A LE HPK+ V +P L +HP
Sbjct: 439 AFRMAEILEAHPKVSHVYYPGLPSHP 464
>UniRef50_A3VS82 Cluster: Cystathionine gamma-synthase; n=1;
Parvularcula bermudensis HTCC2503|Rep: Cystathionine
gamma-synthase - Parvularcula bermudensis HTCC2503
Length = 392
Score = 146 bits (354), Expect = 5e-34
Identities = 73/195 (37%), Positives = 115/195 (58%)
Frame = +3
Query: 33 GDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPL 212
G IV+ D YGGT RLL + F D T E ++ A +I++ETP+NPL
Sbjct: 99 GAKIVAPHDCYGGTYRLLAAHADKGRFEVRFLDQTTEEALRAARDFAPDLIYLETPSNPL 158
Query: 213 LKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNGHSDVIMG 392
+++ D+ +A+ G + + DNTFL+P LQ+PL++G D+V++S TKY+NGH+D+I G
Sbjct: 159 MRITDLSRWTALAKEIG-ALTLADNTFLSPILQRPLEWGCDMVVHSTTKYINGHTDIIGG 217
Query: 393 AAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLIIANWLEKH 572
A I D + +L + NA G+ + D Y R +TL+LR+ + ++ IA+ L H
Sbjct: 218 ALITKDPELASELAWWANATGVTGASFDSYMTLRGARTLSLRVHRAQATAGQIADALVGH 277
Query: 573 PKIVEVLHPXLXTHP 617
P +V + +P L +HP
Sbjct: 278 PAVVGLNYPGLGSHP 292
>UniRef50_A6X770 Cluster: Cystathionine gamma-synthase; n=1;
Ochrobactrum anthropi ATCC 49188|Rep: Cystathionine
gamma-synthase - Ochrobactrum anthropi (strain ATCC
49188 / DSM 6882 / NCTC 12168)
Length = 398
Score = 146 bits (353), Expect = 6e-34
Identities = 77/211 (36%), Positives = 129/211 (61%), Gaps = 8/211 (3%)
Frame = +3
Query: 9 TLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGI-NTTFTDFTNIEKVKNAMQENTK-M 182
TL+ L G I++ +D+YGG RLL V N F DF++ ++ A+ ++ +
Sbjct: 89 TLLEALPAGSSILAHNDLYGGVYRLLADVRPVTAAHNVNFVDFSDEAALRQAVLDHKPAL 148
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
+W ETP+NP L++VD+ + ++ + G I V D+TF +P Q+P+D G +V++S TK
Sbjct: 149 LWFETPSNPTLRIVDLSLVAELGKQAG-AITVCDSTFSSPAGQRPIDHGIHVVVHSATKM 207
Query: 363 MNGHSDVIMGAAIVNDKA---IGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHK 533
+NGHSD++ G V+ A + +++ +LQNA+G V SP DC ++RSLKTL +R
Sbjct: 208 LNGHSDLLGGVVAVSANAPAKLAERVGYLQNALGSVMSPTDCALLHRSLKTLEIRSIRQS 267
Query: 534 KSSLIIANWLEKHPK---IVEVLHPXLXTHP 617
+++L +A LEK + + +V++P L +HP
Sbjct: 268 ETALKLATSLEKRAEELGLTKVVYPGLASHP 298
>UniRef50_Q1AT24 Cluster: Cystathionine gamma-synthase; n=2;
Bacteria|Rep: Cystathionine gamma-synthase - Rubrobacter
xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 410
Score = 145 bits (352), Expect = 8e-34
Identities = 76/201 (37%), Positives = 114/201 (56%), Gaps = 1/201 (0%)
Frame = +3
Query: 18 ALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTD-FTNIEKVKNAMQENTKMIWIE 194
A L G ++++D +YG T LL Q+ G +F D + E K + + +E
Sbjct: 112 AELGEGARVLAADQLYGSTATLLLQIFGPAGTEASFFDAYDPGEAEKKVSSLRPRAVVVE 171
Query: 195 TPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNGH 374
T +NPLL+V DI + +I+RS G ++V DNTF TPYLQ+PL+ GAD+V++S TKY++GH
Sbjct: 172 TISNPLLRVADIPRLAEISRSHGAALIV-DNTFGTPYLQRPLELGADMVVHSATKYLSGH 230
Query: 375 SDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLIIA 554
DV G + L ++ +G P + + ++R LKTL LR+ ++ IA
Sbjct: 231 GDVTAG-VVAAGPPYDAALEQIRKTVGSTLGPFEAWLLHRGLKTLPLRISRQCANARRIA 289
Query: 555 NWLEKHPKIVEVLHPXLXTHP 617
WL +HPK+ V HP L HP
Sbjct: 290 AWLAEHPKVFRVHHPSLEGHP 310
>UniRef50_Q9V088 Cluster: MetB cystathionine gamma-synthase (EC
4.2.99.9) (CGS) (O- succinylhomoserine (Thiol)-lyase);
n=9; Archaea|Rep: MetB cystathionine gamma-synthase (EC
4.2.99.9) (CGS) (O- succinylhomoserine (Thiol)-lyase) -
Pyrococcus abyssi
Length = 393
Score = 145 bits (352), Expect = 8e-34
Identities = 75/206 (36%), Positives = 124/206 (60%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
+T +LL GD +V S + YG T L + ++ + G++ + + + + + E TK+
Sbjct: 92 STLYFSLLEGGDKVVLSMEGYGTTIELAK-LLRKFGVDVKLA-YPSADSLIETIDEETKL 149
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
+ +ET TNP LKV+D+ + K R G I+VV DNTF+TP L KPL+ GA V++SLTKY
Sbjct: 150 VLVETMTNPTLKVIDVPEVAKRCREVGAILVV-DNTFVTPLLYKPLEDGASYVVHSLTKY 208
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
+ GH+DV+ GA + N + D + + +G + P D + + R ++TL +R E +++
Sbjct: 209 IAGHNDVLGGAVLWNGEFSRDLWEW-RRRLGTIIQPFDAWMIERGMRTLEVRFERQSENA 267
Query: 543 LIIANWLEKHPKIVEVLHPXLXTHPH 620
+ IA +L+ HPK+ EV +P L P+
Sbjct: 268 MAIAEFLKDHPKVREVHYPGLKDDPY 293
>UniRef50_P55218 Cluster: O-succinylhomoserine sulfhydrylase; n=95;
Proteobacteria|Rep: O-succinylhomoserine sulfhydrylase -
Pseudomonas aeruginosa
Length = 403
Score = 145 bits (352), Expect = 8e-34
Identities = 72/202 (35%), Positives = 122/202 (60%)
Frame = +3
Query: 12 LVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWI 191
+++L + GDH++ S V+G T L + R GI + +++ + A + NTK+ ++
Sbjct: 105 VMSLCSSGDHVLVSRSVFGSTISLFDKYFKRFGIQVDYPPLSDLAAWEAACKPNTKLFFV 164
Query: 192 ETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNG 371
E+P+NPL ++VDI A+ +IA ++G ++ VDN F TP LQ+PL GAD+V++S TKY++G
Sbjct: 165 ESPSNPLAELVDIAALAEIAHAKG-ALLAVDNCFCTPALQQPLKLGADVVIHSATKYIDG 223
Query: 372 HSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLII 551
+ G + + + + FL+ A G SP + + + L+TL +RM+ H S+L +
Sbjct: 224 QGRGMGGVVAGRGEQMKEVVGFLRTA-GPTLSPFNAWLFLKGLETLRIRMQAHSASALAL 282
Query: 552 ANWLEKHPKIVEVLHPXLXTHP 617
A WLE+ P I V + L +HP
Sbjct: 283 AEWLERQPGIERVYYAGLPSHP 304
>UniRef50_Q493X0 Cluster: Beta-cystathionase; n=2;
Enterobacteriaceae|Rep: Beta-cystathionase - Blochmannia
pennsylvanicus (strain BPEN)
Length = 395
Score = 144 bits (350), Expect = 1e-33
Identities = 72/204 (35%), Positives = 123/204 (60%), Gaps = 1/204 (0%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
T T+++ + GDHI+ + Y T + R V+ R+ I+TT+ D + N +Q NT++
Sbjct: 90 THTILSFVQPGDHILMTGSAYEPTQKFCRYVLKRMNIDTTWFDPLIGNNISNLIQHNTRL 149
Query: 183 IWIETPTNPLLKVVDIEAIVK-IARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTK 359
+ +E+P + ++V D+ +IVK + + + DII+++DNT+ K LD G D+ + S TK
Sbjct: 150 VILESPGSITMEVQDVPSIVKTVRKKKSDIIILLDNTWSAGVFLKALDIGVDVSLQSGTK 209
Query: 360 YMNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKS 539
Y+ GHSD ++G A+ N + D+L+ MG + Y +R L+TL +R++ H+++
Sbjct: 210 YIIGHSDGMIGTAVSNARC-WDQLQEQSYLMGQMVDADTAYMASRGLRTLYVRLKQHEEN 268
Query: 540 SLIIANWLEKHPKIVEVLHPXLXT 611
L +A+WL +HPKI V HP L T
Sbjct: 269 GLHVAHWLAQHPKIERVNHPALST 292
>UniRef50_Q89VE2 Cluster: O-succinylhomoserine sulfhydrylase; n=72;
cellular organisms|Rep: O-succinylhomoserine
sulfhydrylase - Bradyrhizobium japonicum
Length = 417
Score = 144 bits (349), Expect = 2e-33
Identities = 72/211 (34%), Positives = 122/211 (57%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
TT ++A L GDH+V+S ++G +++ ++ R GI TT D ++++ + A++ NTK
Sbjct: 115 TTAILAPLKTGDHVVASRALFGSCLYVIQDLLPRYGIETTLVDGLDLDQWQRALRPNTKT 174
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
++E+PTNP L V+DI I +IA +G +VVDN F TP Q PL GAD+V+YS TK+
Sbjct: 175 FFLESPTNPTLDVLDIPGIAEIAH-KGGARLVVDNVFATPIWQSPLALGADVVVYSATKH 233
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
++G + G + ++ + + L G SP + + + + L+TLA+R+ ++
Sbjct: 234 IDGQGRCLGGIILSSEAFVAEHLHNFMRQTGPSISPFNAWVLLKGLETLAVRVRAQTDTA 293
Query: 543 LIIANWLEKHPKIVEVLHPXLXTHPHTXXLK 635
+A L HPKI +++P HP +K
Sbjct: 294 ASVAEVLAGHPKISRLIYPGRADHPQAALVK 324
>UniRef50_Q1GQF1 Cluster: Cystathionine beta-lyase; n=1;
Sphingopyxis alaskensis|Rep: Cystathionine beta-lyase -
Sphingopyxis alaskensis (Sphingomonas alaskensis)
Length = 415
Score = 144 bits (349), Expect = 2e-33
Identities = 69/202 (34%), Positives = 115/202 (56%)
Frame = +3
Query: 12 LVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWI 191
L A + GDH++ +D VYG T + L V++R G+ + ++ + NT++I++
Sbjct: 110 LTAFVAGGDHLLVADCVYGPTRKFLTDVLARFGVEVEYFRPDIGAEIAGLCRSNTRLIYM 169
Query: 192 ETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNG 371
ETP + ++D+ AI +ARSRG I+ +DNT+ TP KPL G DI + S TKY++G
Sbjct: 170 ETPGSQTFDMIDVPAITAVARSRG-ILTALDNTWATPLFFKPLAHGVDISLASATKYLSG 228
Query: 372 HSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLII 551
HSD ++G A+ +L+ G SP +CY V+R ++TL R+E H++++ +
Sbjct: 229 HSDCLLGTMTAASDAVYRQLKDAAARWGNCASPDNCYLVHRGIRTLDARLERHQRTAATL 288
Query: 552 ANWLEKHPKIVEVLHPXLXTHP 617
W + P++V V +P P
Sbjct: 289 IEWFAQQPEVVAVRYPAHPADP 310
>UniRef50_A6UGP2 Cluster: Cystathionine gamma-synthase; n=1;
Sinorhizobium medicae WSM419|Rep: Cystathionine
gamma-synthase - Sinorhizobium medicae WSM419
Length = 400
Score = 144 bits (349), Expect = 2e-33
Identities = 73/208 (35%), Positives = 122/208 (58%), Gaps = 5/208 (2%)
Frame = +3
Query: 12 LVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWI 191
L +L GDHIV+ Y T+ G+ + D T++ V+NA+ E TK++++
Sbjct: 93 LFGILKAGDHIVADLTTYSSTHEFFDHRAQDFGLKVSLVDCTDVRAVENALTEETKVLYV 152
Query: 192 ETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNG 371
E NP +KV ++A+V++A +RG I+V+ DNTF +P + +P DFG D+V+ S TK++ G
Sbjct: 153 EAIANPTMKVPPLKALVELAHARG-IVVICDNTFASPAVCRPHDFGVDVVVESATKFIGG 211
Query: 372 HSDVIMGA-AIVNDKAIGDKLRFLQ----NAMGIVPSPIDCYFVNRSLKTLALRMEHHKK 536
H+D + G + +D D L ++ N +G SP + + + R +TLALR+E
Sbjct: 212 HNDAVGGVITLKSDILPPDWLEDVRWNTLNKLGAPLSPFNAWLLLRGAQTLALRLEKQCA 271
Query: 537 SSLIIANWLEKHPKIVEVLHPXLXTHPH 620
++L +A LE HP++ V +P L +HP+
Sbjct: 272 NALALAKHLEAHPRVRRVFYPGLPSHPN 299
>UniRef50_O94350 Cluster: Cystathionine beta-lyase; n=27; cellular
organisms|Rep: Cystathionine beta-lyase -
Schizosaccharomyces pombe (Fission yeast)
Length = 390
Score = 143 bits (347), Expect = 3e-33
Identities = 73/190 (38%), Positives = 117/190 (61%), Gaps = 1/190 (0%)
Frame = +3
Query: 39 HIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLK 218
H+V+ D+YGG++RLL + G D +++ + A++ +T ++ IE+PTNP +
Sbjct: 95 HVVAGHDLYGGSDRLLSFNQRQYGFKVDNVDTSDLAAFEAALRPDTNLVLIESPTNPRIS 154
Query: 219 VVDIEAIVKIARSRG-DIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNGHSDVIMGA 395
+ DI AIVKI RS+ D ++V+DNT L+P L PLDFG DIV S TKY++GH D++ G
Sbjct: 155 ICDIRAIVKITRSKAKDALLVMDNTMLSPVLCNPLDFGYDIVYESATKYLSGHHDLMGGV 214
Query: 396 AIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLIIANWLEKHP 575
I + F NAMG +P +C+ + R +KT+ LR+E +++++ IA +L+
Sbjct: 215 IATKSDEIAKSVFFNINAMGAAMAPFECFLLLRGIKTMGLRVERAQQNAIEIAKFLKS-- 272
Query: 576 KIVEVLHPXL 605
K ++V P L
Sbjct: 273 KGLQVNFPGL 282
>UniRef50_Q46V95 Cluster: Cystathionine beta-lyase, bacterial; n=1;
Ralstonia eutropha JMP134|Rep: Cystathionine beta-lyase,
bacterial - Ralstonia eutropha (strain JMP134)
(Alcaligenes eutrophus)
Length = 418
Score = 143 bits (346), Expect = 4e-33
Identities = 72/205 (35%), Positives = 114/205 (55%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
+T L ALL+ GDH++ +D Y T L +V++R G+ D ++ ++ NT++
Sbjct: 101 STALTALLSAGDHVLVTDSAYSPTRAFLERVLARFGVEVETYDPVGGTPIEALLRANTRV 160
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
+++E+P + + DI AI A G VV+DNT+ TP KP G D+ + + TKY
Sbjct: 161 VYVESPGSETFDIQDIPAIAAAAHRHG-AYVVMDNTWGTPLYFKPFAHGVDVSVQAATKY 219
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
+ GHSD ++G N + ++ + MG P D Y R L+TLA+R++ H +S
Sbjct: 220 IVGHSDAMLGVVTCN-RETWPLIKQTTHDMGQTAGPDDIYLALRGLRTLAVRLQRHWQSG 278
Query: 543 LIIANWLEKHPKIVEVLHPXLXTHP 617
L +A WLE P++ VLHP L +HP
Sbjct: 279 LRVAQWLELQPQVEAVLHPALPSHP 303
>UniRef50_A5CVL3 Cluster: O-succinylhomoserine sulfhydrylase; n=3;
Bacteria|Rep: O-succinylhomoserine sulfhydrylase -
Vesicomyosocius okutanii subsp. Calyptogena okutanii
(strain HA)
Length = 388
Score = 143 bits (346), Expect = 4e-33
Identities = 72/203 (35%), Positives = 127/203 (62%)
Frame = +3
Query: 9 TLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIW 188
T++AL GDHIV+S +++G + +L ++++ I+ +F + +++ +N ++ NTK+
Sbjct: 91 TIMALFKSGDHIVASRNMFGTSIIMLNTIITKFNIDISFVNLSDLSAWENTLKNNTKLFL 150
Query: 189 IETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMN 368
+ETP+NPL +VV+I A+ +I+++ I++ VDNT L+P LQ P+ GADIV++S TKY++
Sbjct: 151 LETPSNPLGEVVNINALSRISKA-NSILLAVDNTILSPALQTPITLGADIVIHSATKYID 209
Query: 369 GHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLI 548
G + G + I RFL+ G S + + V + L TL+LRM+ H ++L
Sbjct: 210 GQGRCLAGVIAGSTDIIEQIHRFLRTT-GPSLSAFNAWIVLKGLDTLSLRMKAHSDNALK 268
Query: 549 IANWLEKHPKIVEVLHPXLXTHP 617
+A WLE ++ +V + L +HP
Sbjct: 269 LAIWLEAQDQVEKVYYLGLPSHP 291
>UniRef50_Q67QQ8 Cluster: Cystathionine gamma-lyase; n=1;
Symbiobacterium thermophilum|Rep: Cystathionine
gamma-lyase - Symbiobacterium thermophilum
Length = 395
Score = 142 bits (345), Expect = 6e-33
Identities = 68/205 (33%), Positives = 120/205 (58%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
+ +++ + GDH+V D YG + +SR GI+ T D + + + A++ NT++
Sbjct: 96 SAAILSCVGAGDHVVCVDTAYGPARAFITGYLSRFGISATLVDGCDPAEWEAAVRPNTRL 155
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
++E+P++ L+K+ D+ A+ +AR G I + DN++ T LQ+PL+ G D+V+YS +KY
Sbjct: 156 FYLESPSSGLMKLQDLAAVTALARRHG-IATICDNSYATMLLQRPLELGVDLVVYSCSKY 214
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
GHSDV+ GA + + I Q +G V P + + + R L+TL LR+ H++S+
Sbjct: 215 FGGHSDVLAGAVLGPAERIRRIGDAEQPLLGGVVGPFEAWLIGRGLRTLPLRLRQHQQSA 274
Query: 543 LIIANWLEKHPKIVEVLHPXLXTHP 617
+A +L HP++ V +P +HP
Sbjct: 275 GRVAEFLAGHPRVARVHYPGHPSHP 299
>UniRef50_Q1IZN0 Cluster: Cystathionine gamma-synthase; n=1;
Deinococcus geothermalis DSM 11300|Rep: Cystathionine
gamma-synthase - Deinococcus geothermalis (strain DSM
11300)
Length = 394
Score = 142 bits (344), Expect = 7e-33
Identities = 73/205 (35%), Positives = 118/205 (57%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
+ L+ +L GDHIV+ VYG T LL + + RLGI T+F D ++ V+ A + T++
Sbjct: 93 SAALLGVLKSGDHIVADARVYGVTYALLAEELPRLGITTSFVDACDLGAVEAAFRPETRV 152
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
+ +E+ TNPL+ V D+ + +A +RG ++ VDNTF +P + +P GAD+V +S++KY
Sbjct: 153 LHVESLTNPLMTVPDVPRLADLAHARG-ALLSVDNTFASPAVFRPATHGADLVTHSVSKY 211
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
++GHS+ G + + R +G S D + + LKTL LRM H ++
Sbjct: 212 LSGHSNA-FGGVVCGTTDLIASARTRLTRLGGTMSAFDAWMTLQGLKTLGLRMRAHSGNA 270
Query: 543 LIIANWLEKHPKIVEVLHPXLXTHP 617
+A+ L HP++ V HP L +HP
Sbjct: 271 QAVADVLANHPRVRAVYHPGLSSHP 295
>UniRef50_A1SSS1 Cluster: Cystathionine beta-lyase; n=10;
Gammaproteobacteria|Rep: Cystathionine beta-lyase -
Psychromonas ingrahamii (strain 37)
Length = 407
Score = 142 bits (344), Expect = 7e-33
Identities = 71/205 (34%), Positives = 119/205 (58%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
++ L++ L GDH++ D+ Y T L +++ GI TT+ D + +Q NTK+
Sbjct: 103 SSALMSFLKAGDHLLMLDNAYEPTRALCDTLLAGFGIETTYYDPLIGAGISELIQPNTKV 162
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
+++E+P + +++ D+ + +IA ++IV++DNT+ +P +P + G DI + + TKY
Sbjct: 163 LFLESPGSITMEIQDVPTLSRIAHEN-NLIVMLDNTWASPINSRPFEMGVDISIQAATKY 221
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
+ GHSDV+MG A N K LR +G SP D Y +R L+TL +RM H+K++
Sbjct: 222 IVGHSDVMMGTATANTK-YWPTLREHSYLLGQCTSPDDVYLASRGLRTLGVRMAQHEKNA 280
Query: 543 LIIANWLEKHPKIVEVLHPXLXTHP 617
L +ANWL P++ + HP T P
Sbjct: 281 LAVANWLATRPEVDHLRHPAFETCP 305
>UniRef50_Q8RI68 Cluster: Cystathionine gamma-synthase; n=1;
Fusobacterium nucleatum subsp. nucleatum|Rep:
Cystathionine gamma-synthase - Fusobacterium nucleatum
subsp. nucleatum
Length = 396
Score = 140 bits (340), Expect = 2e-32
Identities = 76/212 (35%), Positives = 122/212 (57%), Gaps = 1/212 (0%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
TTT++ +L GDH+V + ++YG T + +++ + GI+ DF +IE K A++ TK+
Sbjct: 90 TTTIMTILKPGDHVVCNRNIYGETFDVFTKLMPKFGISADLVDFDDIENCKKAIKAETKL 149
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
I+ E NP L + DI + IA G ++++DNTF TP KP+ FGADIV+ SLTK+
Sbjct: 150 IYSEVFANPTLNIADIPTLADIAHKNG-ALLMIDNTFSTPIAIKPIKFGADIVINSLTKF 208
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
MNGHSD I G +I + I D + ++ G P + + +S T+ LR++ ++
Sbjct: 209 MNGHSDAIAG-SITSTTEIIDAIHPVRMLCGTPGDPHAAHAMMKSFATMDLRLKKQMSNA 267
Query: 543 LIIANWLEKHPKIVEVLHPXLXT-HPHTXXLK 635
+A LE++ + +V HP L + H LK
Sbjct: 268 AKLAAALEENKYVSKVNHPSLKSFSQHELALK 299
>UniRef50_Q7X137 Cluster: Cystathionine gamma lyase-like protein;
n=1; Pseudomonas fluorescens|Rep: Cystathionine gamma
lyase-like protein - Pseudomonas fluorescens
Length = 381
Score = 140 bits (340), Expect = 2e-32
Identities = 74/197 (37%), Positives = 117/197 (59%), Gaps = 1/197 (0%)
Frame = +3
Query: 12 LVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWI 191
++ LL G +V + +YG + +L ++ +R+G T D T +K + + M+
Sbjct: 75 VLELLKPGGSLVINKYIYGCSYKLFQRYAARIGAKLTILDLTTESGLKE-LPSDVDMVIF 133
Query: 192 ETPTNPLLKVVDIEAIVK-IARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMN 368
ETPTNP LK +DI A+ K + ++ +VVVDNT+ TP QKPL+FGADI +YS TKY +
Sbjct: 134 ETPTNPFLKDIDIHAVSKAVKQNNPHALVVVDNTWATPIFQKPLNFGADISLYSATKYFS 193
Query: 369 GHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLI 548
GHSDV+ G +VN++ I +L + G + +P + + RS++T LRME H ++
Sbjct: 194 GHSDVMGGLVLVNNEMIYTRLLEGRFYSGSILAPNSAWLLRRSMQTFNLRMEKHSNTTSS 253
Query: 549 IANWLEKHPKIVEVLHP 599
+ N+L + P I V +P
Sbjct: 254 MLNYLRELPFIEHVYYP 270
>UniRef50_Q5FUW3 Cluster: Cystathionine beta-lyase; n=3;
Acetobacteraceae|Rep: Cystathionine beta-lyase -
Gluconobacter oxydans (Gluconobacter suboxydans)
Length = 405
Score = 140 bits (339), Expect = 3e-32
Identities = 74/203 (36%), Positives = 118/203 (58%), Gaps = 1/203 (0%)
Frame = +3
Query: 12 LVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFT-NIEKVKNAMQENTKMIW 188
L+A L GDH++ D VYG T RL ++ R+G+ TT+ T + ++V M+ TK+++
Sbjct: 107 LLAFLGCGDHLLLPDSVYGPTRRLAGTMLQRMGVTTTYYPPTASRDEVLALMRPETKVLF 166
Query: 189 IETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMN 368
E+P + +V D+ + IA G ++++ DNT+ Q P G D+ + +L+KY
Sbjct: 167 AESPGSHTFEVQDVPMLAGIAHEAGALLML-DNTWGIGVFQ-PFTHGVDVSIQALSKYPA 224
Query: 369 GHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLI 548
GHSDVIMG+ VN++A LR +G+ P DC+ R L+T+ +R+ H +S+L
Sbjct: 225 GHSDVIMGSVTVNNEAHWKTLRDAAIQLGLCAGPDDCWLTLRGLRTMGVRLAHQSRSTLE 284
Query: 549 IANWLEKHPKIVEVLHPXLXTHP 617
IA WL+ P++ VLHP L P
Sbjct: 285 IAQWLKTRPEVARVLHPALEDCP 307
>UniRef50_Q6W1U5 Cluster: Cystathionine gamma-synthase; n=2;
Proteobacteria|Rep: Cystathionine gamma-synthase -
Rhizobium sp. (strain NGR234)
Length = 425
Score = 140 bits (339), Expect = 3e-32
Identities = 69/204 (33%), Positives = 117/204 (57%), Gaps = 1/204 (0%)
Frame = +3
Query: 9 TLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIW 188
T + L GDH++ SD Y G N L R+++ GI T + + +++V A + NT+++
Sbjct: 121 TFLTCLKRGDHLIISDVCYAGANELARRMLPDYGIEVTAVNMSRLDEVAAAFRPNTRLVH 180
Query: 189 IETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMN 368
E+P NP+L++ D+ A+ +A G +V VD+T TP +PL G D+V++SLTK++N
Sbjct: 181 CESPCNPILRLTDLSAVAALAHRHG-ALVSVDSTLATPVATRPLALGVDLVIHSLTKFIN 239
Query: 369 GHSDVIMGAAIVNDKAIGDKLRFLQNA-MGIVPSPIDCYFVNRSLKTLALRMEHHKKSSL 545
GH D +G + K + +K+R +G S + + + R + TL R++ S++
Sbjct: 240 GHGDA-LGGIVCGRKELVEKIRSRAGVYLGASLSAQNAWLIMRGIDTLFPRLKAMSDSAM 298
Query: 546 IIANWLEKHPKIVEVLHPXLXTHP 617
IA++L HP + V +P L THP
Sbjct: 299 RIAHFLRDHPGVRSVTYPGLETHP 322
>UniRef50_A0JSU6 Cluster: Cys/Met metabolism
pyridoxal-phosphate-dependent enzymes; n=7;
Actinomycetales|Rep: Cys/Met metabolism
pyridoxal-phosphate-dependent enzymes - Arthrobacter sp.
(strain FB24)
Length = 394
Score = 140 bits (339), Expect = 3e-32
Identities = 72/208 (34%), Positives = 118/208 (56%), Gaps = 4/208 (1%)
Frame = +3
Query: 6 TTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQ----EN 173
++ ++L+ G +V Y G+ + ++ + D + + VK + +
Sbjct: 90 SSALSLIPAGGVLVMPSHSYAGSLVMATELAEKGLFELRTVDIADTDAVKALLAPAEGKP 149
Query: 174 TKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSL 353
M+W+E+PTNP+L + DI A+ A + G IVV DNTF TP +Q+PL G+D+V++S+
Sbjct: 150 ASMLWLESPTNPMLGIADIRALTAAAHAAG-AIVVTDNTFSTPLVQQPLSLGSDVVLHSV 208
Query: 354 TKYMNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHK 533
TKY+ GHSDV++GA + +D AI KL + G + P + + R L+TLALR+E +
Sbjct: 209 TKYLAGHSDVVLGALVTSDAAIRAKLLHHRIIHGGIAGPFEAWLALRGLRTLALRIERSQ 268
Query: 534 KSSLIIANWLEKHPKIVEVLHPXLXTHP 617
S+ ++A L HP+I + P L T P
Sbjct: 269 ASAAVLAGRLSNHPRIESIRFPGLETDP 296
>UniRef50_Q2S2T9 Cluster: Cystathionine beta-lyase MetC; n=1;
Salinibacter ruber DSM 13855|Rep: Cystathionine
beta-lyase MetC - Salinibacter ruber (strain DSM 13855)
Length = 382
Score = 140 bits (338), Expect = 4e-32
Identities = 73/206 (35%), Positives = 115/206 (55%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
++ L+ +L GDH+V+ +YGGT LL ++ R GI T E A+Q NTK+
Sbjct: 79 SSALLGVLEAGDHLVAPHSLYGGTLALLNDLLPRFGITHTLVPEDTPEAWTAALQPNTKV 138
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
++ E TNP L+V+++ +V +A D+ V+DNTF +P +P G D+V++S TKY
Sbjct: 139 LYAEAITNPRLEVLNLTGMVDLAEEH-DLTTVIDNTFASPVNLRPASLGFDVVLHSATKY 197
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
+ GHSDV G K + + L+ +G + P C ++RSLKTL +R+ +++
Sbjct: 198 LGGHSDVAAGVVAGAPKPLDNALQ-TTKLLGGMLDPHACGLLHRSLKTLGVRVRKQNETA 256
Query: 543 LIIANWLEKHPKIVEVLHPXLXTHPH 620
+A L H + V HP L +HPH
Sbjct: 257 RALAAALADHDGVERVHHPSLSSHPH 282
>UniRef50_Q97PS4 Cluster: Transulfuration enzyme family protein;
n=25; Lactobacillales|Rep: Transulfuration enzyme family
protein - Streptococcus pneumoniae
Length = 364
Score = 139 bits (337), Expect = 5e-32
Identities = 72/188 (38%), Positives = 116/188 (61%)
Frame = +3
Query: 33 GDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPL 212
G +++ D+YGG+ R QV + T+ + E++ ++++ +++IETPTNPL
Sbjct: 92 GSKVLAVRDLYGGSFRWFNQVEQEGHFHFTYANTE--EELIAELEKDVDVLYIETPTNPL 149
Query: 213 LKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNGHSDVIMG 392
+ DIE + K+A ++G VVVDNTF +P Q+P++ GADIV++S TKY+ GH+DV+ G
Sbjct: 150 MLEFDIEKLAKLAHAKG-AKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAG 208
Query: 393 AAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLIIANWLEKH 572
+ N + +KL + N G V SP D Y + R LKTL+LRME ++ + +L+
Sbjct: 209 VVVTNSLELYEKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDS 268
Query: 573 PKIVEVLH 596
P + EVL+
Sbjct: 269 PAVKEVLY 276
>UniRef50_A5V1Q1 Cluster: Cystathionine gamma-synthase; n=2;
Roseiflexus|Rep: Cystathionine gamma-synthase -
Roseiflexus sp. RS-1
Length = 409
Score = 139 bits (337), Expect = 5e-32
Identities = 73/196 (37%), Positives = 113/196 (57%), Gaps = 2/196 (1%)
Frame = +3
Query: 42 IVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTK-MIWIETPTNPLLK 218
I+++ D+YG T LL++ + G D ++ V A++ + ++ +E +NPLL+
Sbjct: 114 ILAARDMYGATTLLLQEFFAARGTRIVTCDMCDLNAVDAALEAHRPDVLLVEQLSNPLLR 173
Query: 219 VVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNGHSDVIMGAA 398
V+DI A+ + AR+ G + V D+T +TP LQ+PL GAD+V++S TKY+ GH DV G
Sbjct: 174 VIDIRALAQRARAAGARLAV-DSTIVTPVLQQPLTLGADLVIHSATKYLGGHGDVAGGVV 232
Query: 399 IVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLIIANWLEKHPK 578
+ + D LR +G P + Y + R LKTLALR+ +S+ IA WL HP
Sbjct: 233 VARTGLVRDTLRRQARLLGASLGPFEAYQILRGLKTLALRVRQQCRSAAEIATWLTTHPA 292
Query: 579 IVEVLHPXLXTHP-HT 623
+ V +P L +HP HT
Sbjct: 293 VATVHYPGLASHPQHT 308
>UniRef50_A0VE37 Cluster: Cystathionine beta-lyase; n=2;
Comamonadaceae|Rep: Cystathionine beta-lyase - Delftia
acidovorans SPH-1
Length = 407
Score = 139 bits (337), Expect = 5e-32
Identities = 68/205 (33%), Positives = 120/205 (58%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
T L+ALL+ GDH + +D VY R+ ++ RLGI + + + + ++ NT++
Sbjct: 101 TLVLIALLSPGDHALVADSVYSPVRRVDATLLQRLGITLEYFSPSR-DDLAGKIRPNTRL 159
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
+++E+P++ L +V+D+ A+ +AR G I V DNT+ + +PL+ GA++ + + TKY
Sbjct: 160 VYLESPSSLLYEVLDLPALAAVARRHG-IAVATDNTWSGGWFYQPLEHGANLSIQAATKY 218
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
+ GHSDV+ G I + A+ K+ A+G+ D Y R L+TL +R+ H++ +
Sbjct: 219 IAGHSDVMQGIVITDGPALSKKISTAYEALGLTIGADDAYLALRGLRTLPVRLAQHQRHA 278
Query: 543 LIIANWLEKHPKIVEVLHPXLXTHP 617
IA WLE+ P++ V +P L + P
Sbjct: 279 TEIAQWLEQQPQVGRVFYPALPSDP 303
>UniRef50_A6LZ85 Cluster: O-acetylhomoserine
aminocarboxypropyltransferase; n=2; Clostridium|Rep:
O-acetylhomoserine aminocarboxypropyltransferase -
Clostridium beijerinckii NCIMB 8052
Length = 434
Score = 113 bits (271), Expect(2) = 8e-32
Identities = 55/134 (41%), Positives = 82/134 (61%), Gaps = 1/134 (0%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTN-IEKVKNAMQENTK 179
+ T + + GD IV+ + +YGG+ LL ++ GI F + N IE + + E TK
Sbjct: 97 SNTFLNIAKSGDEIVAVNTLYGGSTTLLNSILPDYGIVGRFVEDENDIESYRKVITEKTK 156
Query: 180 MIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTK 359
I+ E+ NP + ++DIEA+ +A G I ++VDNTF TPYL +P ++GADIV YS TK
Sbjct: 157 AIYSESLGNPGMNIIDIEAVANLAHEHG-IPLIVDNTFATPYLLRPFEYGADIVCYSATK 215
Query: 360 YMNGHSDVIMGAAI 401
Y+ GH I+GA +
Sbjct: 216 YLAGHGTTIVGAVV 229
Score = 47.2 bits (107), Expect(2) = 8e-32
Identities = 20/65 (30%), Positives = 42/65 (64%)
Frame = +3
Query: 426 KLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLIIANWLEKHPKIVEVLHPXL 605
++R+L + +G SP +++ + ++TL+LRM H ++ +A +LE HPK++ V +P L
Sbjct: 270 RIRYLTD-LGAHLSPTSAFYLLQGIETLSLRMREHAANAQKVAEFLEGHPKVLSVAYPGL 328
Query: 606 XTHPH 620
++ +
Sbjct: 329 KSNKY 333
>UniRef50_Q62JZ5 Cluster: Cystathionine beta-lyase; n=37;
Burkholderiales|Rep: Cystathionine beta-lyase -
Burkholderia mallei (Pseudomonas mallei)
Length = 394
Score = 138 bits (335), Expect = 9e-32
Identities = 71/205 (34%), Positives = 110/205 (53%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
T L+ GD ++ D+ YG + + GI F D + + +Q NT++
Sbjct: 94 TNVYFGLVKEGDDVLIPDNAYGPNGDFGKWLAKDFGITARFYDPMIGAGIADLIQPNTRI 153
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
+W+E P + ++V D+ AI +AR+RG I+ +DNT+ KP + G DI + +LTKY
Sbjct: 154 VWLEAPGSVTMEVPDVRAITAVARARG-IVTAIDNTYSAGLAFKPFEHGVDISVQALTKY 212
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
+G SDV+MGA I D + KL+ + +GI S DC V R L ++ R + H +S+
Sbjct: 213 QSGGSDVLMGATITADGELHAKLKLARMRLGIGVSADDCSLVLRGLPSMQARFDAHSRSA 272
Query: 543 LIIANWLEKHPKIVEVLHPXLXTHP 617
L +A WL+ +I VLHP L P
Sbjct: 273 LSLARWLKTRAEIATVLHPQLPDCP 297
>UniRef50_A3UCA9 Cluster: Cystathionine gamma-synthase; n=2;
Hyphomonadaceae|Rep: Cystathionine gamma-synthase -
Oceanicaulis alexandrii HTCC2633
Length = 378
Score = 138 bits (335), Expect = 9e-32
Identities = 73/200 (36%), Positives = 117/200 (58%), Gaps = 2/200 (1%)
Frame = +3
Query: 24 LNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQEN-TKMIWIETP 200
L G H+V+ ++Y G +LL + S+ I+ +F + +I +K A+Q T+++WIETP
Sbjct: 88 LEVGAHVVAQTEMYYGAKKLLHHLASKGLISLSFFEPHDINGLKKAVQGGRTELVWIETP 147
Query: 201 TNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNGHSD 380
NP +VDI +IA G ++ V D+T P + LD GAD+VM+S TKY+NGHSD
Sbjct: 148 ANPSWAIVDIARAAEIAHEAGAMLGV-DSTCAPPCTTRALDLGADLVMHSATKYLNGHSD 206
Query: 381 VIMGAAIVND-KAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLIIAN 557
V+MGA + ++L + G +PS D + + R L+TL +R E ++++ +A
Sbjct: 207 VLMGAVATKEHNERWERLCTGHSLSGAIPSAFDSWLMMRGLRTLFVRYERQSRNAMQLAQ 266
Query: 558 WLEKHPKIVEVLHPXLXTHP 617
L +H + VL+P L +HP
Sbjct: 267 TLSQHKAVSHVLYPGLESHP 286
>UniRef50_Q97W69 Cluster: O-succinylhomoserine (Thiol)-lyase; n=5;
Archaea|Rep: O-succinylhomoserine (Thiol)-lyase -
Sulfolobus solfataricus
Length = 376
Score = 138 bits (334), Expect = 1e-31
Identities = 72/204 (35%), Positives = 122/204 (59%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
+TT +ALL G+ ++ D++G + R + G+N + N ++ A + +
Sbjct: 74 STTALALLKPGNSVLVHRDMFGRSYRFFTDYLKNWGVNVEASYPGNNNIIEKAKSKRYDV 133
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
I++E TNPLL+V+D+ + K+A+ +G I+ +VD TF TP QKPL+ GADIV++S +K+
Sbjct: 134 IFVENITNPLLRVIDVAELSKVAKEQGSIL-IVDATFSTPINQKPLELGADIVVHSASKF 192
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
+ GH+DVI G A K + + + ++ +G P Y R +KTL +RM+ +++
Sbjct: 193 LAGHNDVIAGLAAGYSKYL-NVIDQMRRTLGTSLDPHAAYLTLRGIKTLKIRMDVINRNA 251
Query: 543 LIIANWLEKHPKIVEVLHPXLXTH 614
IA +LE HPK+V+V +P L +H
Sbjct: 252 EQIAEFLEGHPKVVKVYYPGLKSH 275
>UniRef50_Q7UQA0 Cluster: Cystathionine gamma-synthase; n=4;
Bacteria|Rep: Cystathionine gamma-synthase -
Rhodopirellula baltica
Length = 434
Score = 138 bits (333), Expect = 2e-31
Identities = 71/202 (35%), Positives = 114/202 (56%)
Frame = +3
Query: 12 LVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWI 191
L++ L+ GD I+ D Y + + +++ G+ T + ++ A+ TKM+
Sbjct: 135 LMSRLSSGDEIIFFDQCYHRSREFCGKHLAKFGVVTRQVPTGDFAAMEAAITPRTKMLVS 194
Query: 192 ETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNG 371
E+PTNP L VD+E V + ++ +I ++D T TP +PLD G D V +S TKY+ G
Sbjct: 195 ESPTNPHLTCVDLEQFVALGKAH-EIETLIDATLATPMNVRPLDHGVDYVWHSATKYLGG 253
Query: 372 HSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLII 551
H+D++ G I K + D +R L+ +G V SP Y + R LKT +LRM+ H ++ +
Sbjct: 254 HNDLLAGV-ISGRKELLDPIRALRGCLGSVTSPHSMYLLERGLKTFSLRMQRHNENGQAV 312
Query: 552 ANWLEKHPKIVEVLHPXLXTHP 617
A +L +HPKI V +P L +HP
Sbjct: 313 AEFLHQHPKIDRVYYPGLPSHP 334
>UniRef50_Q0APK0 Cluster: Cystathionine beta-lyase; n=1; Maricaulis
maris MCS10|Rep: Cystathionine beta-lyase - Maricaulis
maris (strain MCS10)
Length = 385
Score = 138 bits (333), Expect = 2e-31
Identities = 65/205 (31%), Positives = 114/205 (55%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
T +++A G ++++D +YG L +SR G+ T F ++ + + + T+
Sbjct: 83 TLSILAATEAGGEVLAADCIYGPVRNFLTTQMSRYGVRTRFFAPQMGAEIGDLITDETQA 142
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
I +E+P + +++ D+ AI K+AR +G +I ++D+T+ KPL G D + +LTKY
Sbjct: 143 ILLESPGSLTMEMQDVPAIAKVARDKG-VITIIDDTWSAGLTMKPLQLGVDYAVQALTKY 201
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
+ GHSD++MGA + D A+ +L+ + A G P D Y R L+++ +RM+ +SS
Sbjct: 202 VGGHSDLLMGAVVARDDALFQRLQTTERAFGFHTGPDDAYLALRGLRSMGVRMQRSAESS 261
Query: 543 LIIANWLEKHPKIVEVLHPXLXTHP 617
L IA WL ++ + HP HP
Sbjct: 262 LTIAEWLAARAEVGAIRHPARSDHP 286
>UniRef50_Q98K64 Cluster: Methionine gamma-lyase; n=13;
Bacteria|Rep: Methionine gamma-lyase - Rhizobium loti
(Mesorhizobium loti)
Length = 427
Score = 137 bits (332), Expect = 2e-31
Identities = 81/206 (39%), Positives = 120/206 (58%), Gaps = 11/206 (5%)
Frame = +3
Query: 6 TTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTT-FTDFTNIEKVKNAMQE---- 170
TTL+A GD I+ S +YGGT LL + +S GI F D + + V+ A
Sbjct: 113 TTLLAYARPGDVILHSQPLYGGTETLLTRTLSGFGIGAVGFADGVDEKAVRAAADAAVAK 172
Query: 171 -NTKMIWIETPTNPLLKVVDIEAIVKIA----RSRGDI-IVVVDNTFLTPYLQKPLDFGA 332
+I IETP+NP +VDI + IA S+G I+V DNT L P Q+P++ GA
Sbjct: 173 GRVSVILIETPSNPTNSLVDIALMRMIADEIGASQGSAPIIVCDNTLLGPVFQRPIEHGA 232
Query: 333 DIVMYSLTKYMNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLA 512
D+ +YSLTKY+ GHSD+I GAA + KA+ ++ L+ A+G P C+ + RSL+TL+
Sbjct: 233 DVSVYSLTKYVGGHSDLIAGAA-MGSKAVTKPIKALRGAIGTQLDPHSCWMLGRSLETLS 291
Query: 513 LRMEHHKKSSLIIANWLEKHPKIVEV 590
+RME ++ ++A +L H K+ +V
Sbjct: 292 IRMERANDNARLVAEFLRDHAKVEKV 317
>UniRef50_A5EU95 Cluster: Cystathionine beta-lyase; n=1;
Bradyrhizobium sp. BTAi1|Rep: Cystathionine beta-lyase -
Bradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182)
Length = 415
Score = 137 bits (332), Expect = 2e-31
Identities = 72/228 (31%), Positives = 118/228 (51%), Gaps = 1/228 (0%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
T +A+ GD ++ + +YG ++ + + LGI D + + E T++
Sbjct: 89 TLATMAVCRSGDRVLMPETLYGPARDMILRFLGPLGIAAQTYDPLLDAGIAGLLDERTRL 148
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
+W+E+P + +V D+ AIV +A+ G +V DNT+ + L KPL G DI M +L+K+
Sbjct: 149 VWVESPGSATFEVQDVPAIVAVAKKVG-ALVAADNTWASHLLFKPLTHGVDISMQALSKH 207
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
GH D++MG+ V D+A+ +L+ +G SP DC R L T+ +RM H S+
Sbjct: 208 AGGHGDLLMGSLAVRDQALFRRLKDTARFLGYGVSPEDCALCERGLMTMPVRMRHAAASA 267
Query: 543 LIIANWLEKHPKIVEVLHPXLXTHP-HTXXLKNX*RVTRVCSVSNXPE 683
I WL + P++ +LHP + HP H ++ V SV PE
Sbjct: 268 AEIMTWLSQRPEVARILHPAMPDHPGHAVWKRDFSGAAAVFSVVLRPE 315
>UniRef50_O02215 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 451
Score = 137 bits (331), Expect = 3e-31
Identities = 71/209 (33%), Positives = 117/209 (55%), Gaps = 4/209 (1%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEK----VKNAMQE 170
+ + L+ G H++ + +Y GT+ + + ++R G+ T D + V+ A++
Sbjct: 146 SAVFLEFLSSGAHMIVMNPIYSGTSSFINETLARFGVEITSVDVEKEKDFAGAVEKAIRP 205
Query: 171 NTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYS 350
NTKMI+ E+ NP + V DI +++A+ + I+ +D TF +PY +PL GADI ++S
Sbjct: 206 NTKMIYFESIANPTMAVPDILGTIEVAK-KYKILTCLDATFSSPYNIQPLKLGADISLHS 264
Query: 351 LTKYMNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHH 530
+KY+ GH+DVI G V+ KL+ Q G SP D + R LKTL LR++
Sbjct: 265 CSKYIGGHTDVIAGVVTVSSYDNWKKLKLQQLTTGSSLSPYDAALLTRGLKTLGLRVDRI 324
Query: 531 KKSSLIIANWLEKHPKIVEVLHPXLXTHP 617
+++ A +LE HPK+ V +P L +HP
Sbjct: 325 SENAQKTAEFLESHPKVERVFYPGLPSHP 353
>UniRef50_Q52811 Cluster: Putative cystathionine beta-lyase; n=35;
Proteobacteria|Rep: Putative cystathionine beta-lyase -
Rhizobium leguminosarum bv. viciae (strain 3841)
Length = 396
Score = 137 bits (331), Expect = 3e-31
Identities = 70/205 (34%), Positives = 112/205 (54%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
T + + GDH + D VYG T ++ RLG+ + ++ + NTK+
Sbjct: 93 TIPFLGFVAAGDHALVVDSVYGPTRHFCDTMLKRLGVEVEYYHPEIGAGIETLFRSNTKL 152
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
+ E P + ++ DI AI +A G +V++DNT+ TP +PLD G DI +++ TKY
Sbjct: 153 VHTEAPGSNTFEMQDIPAISAVAHRHG-AVVMMDNTWATPVYFRPLDHGVDISIHASTKY 211
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
+GHSD+++G N + ++L+ +GI +P D Y + R L+T+ LR+E H +S+
Sbjct: 212 PSGHSDILLGTVSANAEH-WERLKEANGVLGICGAPDDAYQILRGLRTMGLRLERHYESA 270
Query: 543 LIIANWLEKHPKIVEVLHPXLXTHP 617
L IA WLE + VLHP L + P
Sbjct: 271 LDIAKWLEGRDDVARVLHPALPSFP 295
>UniRef50_O69592 Cluster: O-succinylhomoserine sulfhydrylase; n=19;
Bacteria|Rep: O-succinylhomoserine sulfhydrylase -
Mycobacterium leprae
Length = 426
Score = 136 bits (330), Expect = 4e-31
Identities = 71/204 (34%), Positives = 121/204 (59%)
Frame = +3
Query: 6 TTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMI 185
T+L ALL GD +V++ ++G + +++ R G+ T F D ++ + + A+ T+ +
Sbjct: 123 TSLGALLASGDRLVAARSLFGSCFVVCNEILPRWGVETVFVDGEDLVQWEQALSVPTQAV 182
Query: 186 WIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYM 365
+ ETP+NP+ +VDI A+ ++A + G VV+DN F TP LQ L G D+V+YS TK++
Sbjct: 183 FFETPSNPMQSLVDIAAVTELAHAAG-AKVVLDNAFATPLLQHGLPLGVDVVIYSGTKHI 241
Query: 366 NGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSL 545
+G V+ GA + + I ++ L G S + + + + L+TLA+R++H S+
Sbjct: 242 DGQGRVLGGAILGDRDYIDGPVQKLMRHTGPAMSAFNAWILLKGLETLAIRVDHCNSSAH 301
Query: 546 IIANWLEKHPKIVEVLHPXLXTHP 617
IA +LEKHP + V +P L +HP
Sbjct: 302 RIAEFLEKHPAVSWVRYPFLVSHP 325
>UniRef50_Q6L1U0 Cluster: Cystathionine beta-lyase; n=1; Picrophilus
torridus|Rep: Cystathionine beta-lyase - Picrophilus
torridus
Length = 364
Score = 136 bits (330), Expect = 4e-31
Identities = 70/205 (34%), Positives = 121/205 (59%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
TTTL+++L GD V+ D + + + + GI T + E + + + TK+
Sbjct: 69 TTTLLSILRPGDEAVTHIDTFARSYHFFSEFLRSFGIKTRISR-PGTENILEEINKRTKL 127
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
++IET +NP+L+V DI+ I K G +++ D+TF TPY K LD GAD+V++S +K+
Sbjct: 128 VFIETLSNPVLRVYDIDEISKACSENGALLIC-DSTFATPYNLKTLDHGADVVIHSASKF 186
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
++GH+DVI G A + I ++ + ++G P + V R +KTL LRME +++
Sbjct: 187 LSGHNDVIAGVAAGSYDLI-KRIDDTRRSLGTSMDPNTAFLVERGIKTLDLRMERINENA 245
Query: 543 LIIANWLEKHPKIVEVLHPXLXTHP 617
+ IA +L + P++ +V++P L +HP
Sbjct: 246 MKIARFLNESPRVSDVIYPGLESHP 270
>UniRef50_Q5K6Y9 Cluster: Cystathionine gamma-lyase, putative; n=1;
Filobasidiella neoformans|Rep: Cystathionine
gamma-lyase, putative - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 466
Score = 136 bits (329), Expect = 5e-31
Identities = 79/207 (38%), Positives = 122/207 (58%), Gaps = 18/207 (8%)
Frame = +3
Query: 33 GDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNI--EKVKNAMQENTKMIWIETPTN 206
G HI++ +DVYGGT R +V G++ T+ D E ++ A++ +T+++W+E PTN
Sbjct: 112 GGHILAVNDVYGGTARYFSRVARPTGLDITYLDMIEAGEEGIRAAIRPDTRLVWLEIPTN 171
Query: 207 PLLKVVDIEAIVKIARSRGDI---IVVVDNTFLTPYLQKPLDFG-------ADIVMYSLT 356
P L V + I I +S + +++VD TFL+ + PL ADI SL+
Sbjct: 172 PTLLVHPLPLISSIVKSLPEEHRPLILVDTTFLSSFNFTPLVGANPESTPLADIAYSSLS 231
Query: 357 KYMNGHSDVIMGAAIVNDKAIGDK------LRFLQNAMGIVPSPIDCYFVNRSLKTLALR 518
KY +GHSD+I+G+ V+ + + LRFLQN+MG PSP DC+ + RSLKTL+ R
Sbjct: 232 KYSSGHSDIILGSVTVSPQTARFRPELIKALRFLQNSMGACPSPYDCHLMIRSLKTLSTR 291
Query: 519 MEHHKKSSLIIANWLEKHPKIVEVLHP 599
M H ++L IA +L+ P++ EV +P
Sbjct: 292 MIKHGVNALRIAAFLDNQPQVSEVRYP 318
>UniRef50_Q07703 Cluster: Cystathionine beta-lyase; n=6;
Burkholderiales|Rep: Cystathionine beta-lyase -
Bordetella avium
Length = 396
Score = 136 bits (329), Expect = 5e-31
Identities = 66/201 (32%), Positives = 120/201 (59%)
Frame = +3
Query: 15 VALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWIE 194
++LL+ G+H + +D YG + L V+SRLGI+ TF D + + ++ T++I+ E
Sbjct: 103 LSLLSAGEHALVADCAYGPVHELHEAVLSRLGIDVTFFDAK--ADLASLVRPTTRLIFAE 160
Query: 195 TPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNGH 374
P + L +++D+ A+ + A+ D+I+ DNT+ + Y+ +PL GA + + + TKY+ GH
Sbjct: 161 APGSLLFEMLDMPALARFAKQH-DLILATDNTWGSGYIYRPLTLGAQVSVIAGTKYVGGH 219
Query: 375 SDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLIIA 554
SD+++GA + ND+AI +L Q A+G S D + R ++T+ +RM H + +L +
Sbjct: 220 SDLMLGAVVTNDEAIAKRLNRTQYALGYSVSADDAWLALRGVRTMPVRMAQHARHALEVC 279
Query: 555 NWLEKHPKIVEVLHPXLXTHP 617
+L+ P++V + HP P
Sbjct: 280 EFLQNRPEVVRLYHPAWPADP 300
>UniRef50_Q47S97 Cluster: Cystathionine gamma-synthase; n=1;
Thermobifida fusca YX|Rep: Cystathionine gamma-synthase
- Thermobifida fusca (strain YX)
Length = 406
Score = 135 bits (327), Expect = 9e-31
Identities = 72/202 (35%), Positives = 116/202 (57%)
Frame = +3
Query: 9 TLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIW 188
TL+AL + G H+V+S +YG T +LL V+ R G+ F D T+ V+ A + T +++
Sbjct: 97 TLLALTHAGAHVVASRALYGNTYKLLDVVLRRFGVAVDFVDITDPAAVRAAFRPETVLVY 156
Query: 189 IETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMN 368
ET NP + V D+ + +A G ++VVD+TF +P + +PL+ GADIV++S TKY+
Sbjct: 157 TETLANPTMTVSDLPVLAALAHEAG-ALLVVDSTFASPVVCRPLEHGADIVLHSATKYLG 215
Query: 369 GHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLI 548
GHSD G A+ + ++R + +G + + + ++R L+TL LRM ++
Sbjct: 216 GHSDATGGVAVGRPDLLA-RIREARIDLGPHLAADEAFLLHRGLETLPLRMARQCATAAE 274
Query: 549 IANWLEKHPKIVEVLHPXLXTH 614
A L +HP + V HP L TH
Sbjct: 275 FAAALAEHPAVARVDHPSLPTH 296
>UniRef50_A6W2A4 Cluster: Cystathionine beta-lyase; n=1; Marinomonas
sp. MWYL1|Rep: Cystathionine beta-lyase - Marinomonas
sp. MWYL1
Length = 388
Score = 135 bits (327), Expect = 9e-31
Identities = 66/200 (33%), Positives = 118/200 (59%)
Frame = +3
Query: 18 ALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWIET 197
A + GDH++ D ++ T + ++R G+ + + N + ++ NTK++ IE+
Sbjct: 97 AYVGAGDHLLVVDTIFSATRTYCEKQLTRNGVEIEYFPW-NTTDISPYLKSNTKVVMIES 155
Query: 198 PTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNGHS 377
P + +V+D+ + + A D+IV+ DNT+ + +L +PL+ G D+ + + TKY+ GH+
Sbjct: 156 PASQTYEVMDLPKLCESAHEH-DLIVIADNTYGSSWLYQPLELGCDVSVIAGTKYLGGHA 214
Query: 378 DVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLIIAN 557
DV+MGAA+V A+ + LR L + G SP + Y R ++TL LR++ H ++SL +A
Sbjct: 215 DVMMGAAVVKKHAM-NPLRSLVHITGQTLSPDEAYACLRGMRTLDLRLQRHGENSLAVAK 273
Query: 558 WLEKHPKIVEVLHPXLXTHP 617
WL + ++ +LHP L HP
Sbjct: 274 WLLQRAEVKSILHPGLQDHP 293
>UniRef50_A0L907 Cluster: Cystathionine gamma-synthase; n=1;
Magnetococcus sp. MC-1|Rep: Cystathionine gamma-synthase
- Magnetococcus sp. (strain MC-1)
Length = 396
Score = 135 bits (327), Expect = 9e-31
Identities = 68/200 (34%), Positives = 118/200 (59%), Gaps = 1/200 (0%)
Frame = +3
Query: 21 LLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWIETP 200
LL GDH++ S V+G T + + +++ GI F +++ + A++ NTKM ++E+P
Sbjct: 99 LLQQGDHLILSRSVFGSTINVAKNYLTKFGIQIDFVGLADMDGWRRAIRPNTKMFYLESP 158
Query: 201 TNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNGHSD 380
NP L++ D+ A+ ++A+ G I +VVDN F TP LQ PL+ GA +V++S TKY++G
Sbjct: 159 ANPTLEMADLAALGQLAKEHG-IKMVVDNVFCTPILQNPLNLGAHLVVHSATKYLDGQGR 217
Query: 381 VIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLIIANW 560
V+ G + + + I +R G SP + + + + L+TL LR+E H +++ +A
Sbjct: 218 VLGGGIVGDVELIEGPMRTYMRNAGPALSPFNAWVLYKGLETLGLRVERHCANAMQVAQA 277
Query: 561 L-EKHPKIVEVLHPXLXTHP 617
L E+ +V +P L +HP
Sbjct: 278 LFERADTTHKVRYPGLESHP 297
>UniRef50_A3JID5 Cluster: Cystathionine beta-lyase; n=3;
Marinobacter|Rep: Cystathionine beta-lyase -
Marinobacter sp. ELB17
Length = 397
Score = 134 bits (325), Expect = 1e-30
Identities = 69/200 (34%), Positives = 119/200 (59%), Gaps = 1/200 (0%)
Frame = +3
Query: 21 LLNHGDH-IVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWIET 197
L HG + IV D+YGGT LL LGI F +++++ + + +++ ET
Sbjct: 99 LFAHGRNGIVCVGDLYGGTQELLMNHFEPLGIPFIFLLNQQLDELEQHLTKPGMLVYCET 158
Query: 198 PTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNGHS 377
P NP + ++DI + + A ++G ++ VDNTF +P Q+PL+ GAD+VM+S TKY+ GHS
Sbjct: 159 PANPTMAILDIADLARRAHAKG-ALMAVDNTFASPINQRPLELGADLVMHSATKYLAGHS 217
Query: 378 DVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLIIAN 557
D+ G A ++ + + + ++G + +P ++RSL+TL +R+ H ++++ +A
Sbjct: 218 DLTAG-AFMSSAELAKPVAAWRKSLGQILAPEMAALLSRSLRTLHVRVRQHNENAMAVAI 276
Query: 558 WLEKHPKIVEVLHPXLXTHP 617
+EKHPK+ VL+P L P
Sbjct: 277 AMEKHPKVSRVLYPGLPDFP 296
>UniRef50_Q1ITX7 Cluster: Cystathionine gamma-lyase; n=1;
Acidobacteria bacterium Ellin345|Rep: Cystathionine
gamma-lyase - Acidobacteria bacterium (strain Ellin345)
Length = 459
Score = 133 bits (321), Expect = 5e-30
Identities = 74/213 (34%), Positives = 124/213 (58%), Gaps = 8/213 (3%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
+ ++ AL GD +V+ + +YG T L+ + R G+ T F D N +++ A+ +T++
Sbjct: 124 SASICALTRAGDQVVAHNTLYGCTYSLMTNWLPRQGVATRFVDMRNPKEIAKAINAHTRI 183
Query: 183 IWIETPTNPLLKVVDIEAIVKIA----RSRGD---IIVVVDNTFLTPYLQKPLDFGADIV 341
++ ETP NP L+++DI A+ +I + R + I VVVDNTF TP+ Q+PL GA +V
Sbjct: 184 VYFETPVNPNLELIDIAAVREIVDHANKGRSELEQIRVVVDNTFATPFCQRPLTLGAHMV 243
Query: 342 MYSLTKYMNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFV-NRSLKTLALR 518
++SLTK + G MG ++ K++ + L + G SP + V L +LA R
Sbjct: 244 VHSLTKGIGGFG-TDMGGVVIGPKSLHNVLLMYRKDFGGSLSPKPAWNVLVYGLPSLAAR 302
Query: 519 MEHHKKSSLIIANWLEKHPKIVEVLHPXLXTHP 617
M + +K++ +A WLE+HPK+ +V +P L + P
Sbjct: 303 MANMQKTAQYVAEWLEQHPKVEKVFYPGLESFP 335
>UniRef50_Q98LV9 Cluster: Methionine gamma lyase; n=4;
Rhizobiales|Rep: Methionine gamma lyase - Rhizobium loti
(Mesorhizobium loti)
Length = 395
Score = 132 bits (320), Expect = 6e-30
Identities = 65/205 (31%), Positives = 116/205 (56%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
+ T++A + G+ IV+ + YG RL +++ RL I + D ++ + V A+ K+
Sbjct: 97 SATVLAFVGAGERIVAVRNCYGDAYRLFERLLPRLNIKVDYVDGSDPDAVAAALP-GAKL 155
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
+++E+PT+ + ++ DI + ++A+ +G I+ +DN++ TP QKP+ G D+V++S +KY
Sbjct: 156 LYLESPTSMMFELQDIAHLTRLAKEQG-IVTTIDNSWATPVFQKPISHGVDLVLHSASKY 214
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
+ GHSD + G + I + +G SP + + + R L+TL LR+ HH KS
Sbjct: 215 LGGHSDTVAGVVAGSAAHIKHINEQTYSYLGGKLSPFEAWLLLRGLRTLPLRLPHHMKSG 274
Query: 543 LIIANWLEKHPKIVEVLHPXLXTHP 617
L +A L+ H + V HP HP
Sbjct: 275 LTLAERLKAHAHVERVNHPAYSNHP 299
>UniRef50_A0JSB0 Cluster: O-acetylhomoserine/O-acetylserine
sulfhydrylase; n=130; cellular organisms|Rep:
O-acetylhomoserine/O-acetylserine sulfhydrylase -
Arthrobacter sp. (strain FB24)
Length = 444
Score = 113 bits (273), Expect(2) = 8e-30
Identities = 56/131 (42%), Positives = 81/131 (61%)
Frame = +3
Query: 9 TLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIW 188
T AL GDHIV++ +YGGT L + R G++TTF T+ A++ENTK I+
Sbjct: 94 TFAALTQAGDHIVAASQLYGGTVTQLDVTLRRFGVDTTFVPGTDPADYAAAVRENTKAIF 153
Query: 189 IETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMN 368
+E NP +V D+E + K+AR G I +VVD T TPYL +P++ GADIV++S TK++
Sbjct: 154 VEVVANPSSEVQDLEGLAKVARDAG-IPLVVDATLSTPYLVRPIEHGADIVIHSATKFLG 212
Query: 369 GHSDVIMGAAI 401
GH + G +
Sbjct: 213 GHGTTLGGVIV 223
Score = 39.5 bits (88), Expect(2) = 8e-30
Identities = 21/66 (31%), Positives = 35/66 (53%), Gaps = 1/66 (1%)
Frame = +3
Query: 426 KLRFLQ-NAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLIIANWLEKHPKIVEVLHPX 602
KLR Q +G SP + + + ++TL R++ H K++ +A WLE ++ V
Sbjct: 262 KLRCEQLRDIGPALSPQSAFQLLQGVETLPQRLDEHLKNAQAVAEWLEADERVAYVNFSG 321
Query: 603 LXTHPH 620
L +HPH
Sbjct: 322 LPSHPH 327
>UniRef50_Q11C77 Cluster: Cystathionine beta-lyase; n=1;
Mesorhizobium sp. BNC1|Rep: Cystathionine beta-lyase -
Mesorhizobium sp. (strain BNC1)
Length = 388
Score = 132 bits (318), Expect = 1e-29
Identities = 69/205 (33%), Positives = 117/205 (57%), Gaps = 1/205 (0%)
Frame = +3
Query: 12 LVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWI 191
++ LLN GDH++ D VY R +++R+GI + D +++ ++ NT++I++
Sbjct: 95 MLGLLNSGDHVLIPDSVYDIVRRSADGMLARMGIEYEYYDPVVGAGIESLLRPNTRLIYL 154
Query: 192 ETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNG 371
E+P + +V D+ AIV +A++R +I +DNT+ TP +PL+ G D V+ + TKY+ G
Sbjct: 155 ESPGSGTFEVQDVPAIVAVAKAR-NIRTAIDNTWATPVFFRPLELGVDAVIEAGTKYIVG 213
Query: 372 HSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLII 551
HSD ++G N+ G +R G V + R L+T+ +R++ H ++L I
Sbjct: 214 HSDAMLGVVAANELTYG-PIRQAIRDFGAVVGTEEANLGLRGLRTMEVRLQRHFAAALEI 272
Query: 552 ANWLEKHPKIVEVLHPXLXTHP-HT 623
A WLE P + V+HP L + P HT
Sbjct: 273 ATWLEGQPGVARVMHPALPSFPGHT 297
>UniRef50_Q0C2A8 Cluster: Cystathionine beta-lyase; n=1; Hyphomonas
neptunium ATCC 15444|Rep: Cystathionine beta-lyase -
Hyphomonas neptunium (strain ATCC 15444)
Length = 389
Score = 131 bits (316), Expect = 2e-29
Identities = 63/202 (31%), Positives = 114/202 (56%)
Frame = +3
Query: 12 LVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWI 191
+ +++ G H + +D YG T R + + +G+ D ++ ++NT+ I +
Sbjct: 89 IASVVEAGGHFLFTDSAYGPTARFCEKRLKAMGVEAERFDPRMGAGIERLFRDNTQAILV 148
Query: 192 ETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNG 371
E+P + ++ D+ A+ ++A++RG I +V DNT+ KPL GAD+ + +LTKY+ G
Sbjct: 149 ESPGSLTFEISDLPAMAQVAKARG-IRIVCDNTWGAGLHYKPLALGADLSVQALTKYVVG 207
Query: 372 HSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLII 551
HSD GA + N+ ++ +K+ GI +P D Y R +++L R++ H+ + L +
Sbjct: 208 HSDAFGGAVMTNELSLANKVANCSEDWGIGLAPDDAYLAVRGIRSLTTRLKAHEAAGLEL 267
Query: 552 ANWLEKHPKIVEVLHPXLXTHP 617
A WLE P++ V+HP L +HP
Sbjct: 268 AQWLEGRPEVASVIHPALPSHP 289
>UniRef50_Q7W586 Cluster: Cystathionine beta-lyase; n=3;
Bordetella|Rep: Cystathionine beta-lyase - Bordetella
parapertussis
Length = 413
Score = 130 bits (315), Expect = 2e-29
Identities = 66/204 (32%), Positives = 113/204 (55%)
Frame = +3
Query: 6 TTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMI 185
TTL L G HI+ D+VY +V++ G+ + + +E++ ++ +T ++
Sbjct: 118 TTLNTLARPGSHILVPDNVYYPCREFCEKVLAPRGVRVEYYAGSEVERL---VRPDTSVV 174
Query: 186 WIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYM 365
+ E+P + +++ D I A + G VV DNT+ TP +P + G D+ +++ TKY+
Sbjct: 175 YCESPGSLTMEMQDFARIAAAAHAVG-AKVVADNTWATPVFLQPFEHGIDVSIHAATKYL 233
Query: 366 NGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSL 545
GHSDV+MG +D + +R A G+ SP D Y R ++TL +RM H +++L
Sbjct: 234 VGHSDVMMGTVTAHDPELWLAIRTEAAAQGLSISPDDAYLATRGIRTLGVRMAAHYRNAL 293
Query: 546 IIANWLEKHPKIVEVLHPXLXTHP 617
+A WL HP++ +VL+P L HP
Sbjct: 294 DVAQWLAGHPRVAQVLYPALPQHP 317
>UniRef50_P53101 Cluster: Cystathionine beta-lyase; n=5;
Saccharomycetales|Rep: Cystathionine beta-lyase -
Saccharomyces cerevisiae (Baker's yeast)
Length = 465
Score = 130 bits (315), Expect = 2e-29
Identities = 72/185 (38%), Positives = 106/185 (57%), Gaps = 5/185 (2%)
Frame = +3
Query: 27 NHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM--IWIETP 200
NH I++ DD+YGGT RLL + + D ++ EK K Q K+ + +E+P
Sbjct: 98 NHTPTIIAGDDLYGGTQRLLNFFKQQSHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESP 157
Query: 201 TNPLLKVVDIEAIVKIARSRG-DIIVVVDNTFLTPYLQKPLDF--GADIVMYSLTKYMNG 371
TNPL KVVDI I++ + D VVVDNT ++ PL G D+V S TKY+NG
Sbjct: 158 TNPLCKVVDIPRILRFVKCISPDTTVVVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNG 217
Query: 372 HSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLII 551
H D++ G I I KL F+ N+ G SP+D + + R LKTL +R+ +++++I+
Sbjct: 218 HHDLMGGVIISKTPEIASKLYFVINSTGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMIL 277
Query: 552 ANWLE 566
A+WLE
Sbjct: 278 AHWLE 282
>UniRef50_P44527 Cluster: Cystathionine beta-lyase; n=78;
Gammaproteobacteria|Rep: Cystathionine beta-lyase -
Haemophilus influenzae
Length = 396
Score = 130 bits (315), Expect = 2e-29
Identities = 68/214 (31%), Positives = 123/214 (57%), Gaps = 2/214 (0%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
T ++++ + GDH++ S Y T V+ ++ I+ T+ D E + +Q NTK+
Sbjct: 92 TNSILSFVKTGDHVLMSGAAYEPTQYFCNIVLKKMQIDITYYDPLIGEDIATLIQPNTKV 151
Query: 183 IWIETPTNPLLKVVDIEAIVKIARS-RGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTK 359
+++E P++ +++ DI IVK AR +I++++DNT+ L K L+ DI + + TK
Sbjct: 152 LFLEAPSSITMEIPDIPTIVKAARKVNPNIVIMIDNTWSAGVLFKALEHDIDISIQAGTK 211
Query: 360 YMNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKS 539
Y+ GHSD+++G A+ N + D+LR MG + Y R ++TL +R++ H++S
Sbjct: 212 YLVGHSDIMIGTAVANART-WDQLREHSYLMGQMVDADSAYTTARGIRTLGVRLKQHQES 270
Query: 540 SLIIANWLEKHPKIVEVLHPXLXTHP-HTXXLKN 638
S+ +A WL + P++ V HP L + P H L++
Sbjct: 271 SIKVAKWLSEQPEVKTVYHPALPSCPGHEFFLRD 304
>UniRef50_Q9X0Z7 Cluster: Cystathionine gamma-synthase; n=2;
Thermotoga|Rep: Cystathionine gamma-synthase -
Thermotoga maritima
Length = 379
Score = 130 bits (314), Expect = 3e-29
Identities = 63/197 (31%), Positives = 118/197 (59%)
Frame = +3
Query: 9 TLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIW 188
+++ L+ GDH+V D+ Y + + + I ++ + E++ A+ + TK+I+
Sbjct: 88 SILHFLSSGDHVVCVDEAYSWAKKFFNYLSKKFDIEVSYVP-PDAERIVEAITKKTKLIY 146
Query: 189 IETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMN 368
+E+PT+ +KV+DI + + A I V+DNT+ +P QKP G D+V++S TKY++
Sbjct: 147 LESPTSMRMKVIDIRKVTEAAGEL-KIKTVIDNTWASPIFQKPKLLGVDVVVHSATKYIS 205
Query: 369 GHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLI 548
GH DV+ G + + + + +G V SPI+ + + R L+TL LRM+ H +++L+
Sbjct: 206 GHGDVMAGVIAGDVEDMKNIFVDEYKNIGPVLSPIEAWLILRGLRTLELRMKKHYENALV 265
Query: 549 IANWLEKHPKIVEVLHP 599
++++L HPK++EV +P
Sbjct: 266 VSDFLMDHPKVLEVNYP 282
>UniRef50_Q01X62 Cluster: Cystathionine gamma-synthase; n=1;
Solibacter usitatus Ellin6076|Rep: Cystathionine
gamma-synthase - Solibacter usitatus (strain Ellin6076)
Length = 415
Score = 130 bits (314), Expect = 3e-29
Identities = 71/207 (34%), Positives = 114/207 (55%), Gaps = 3/207 (1%)
Frame = +3
Query: 6 TTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQ--ENTK 179
T A +V + +YGGT L+ + + LG+ E ++ A++ N
Sbjct: 109 TAFFAYARPDSTMVYTTPLYGGTTGLIHKFMKPLGVTGIPVTSGKTEAIEEAIRGARNCC 168
Query: 180 MIWIETPTNPLLKVVDIEAIVKIARSRGDI-IVVVDNTFLTPYLQKPLDFGADIVMYSLT 356
M+++ETP NP + + DIE + A D +V+VDNTFL P Q PL GA+I +YS T
Sbjct: 169 MVYLETPANPTMIMTDIERAAEAAAKHPDKPVVMVDNTFLGPSFQHPLLLGANICLYSAT 228
Query: 357 KYMNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKK 536
KY++G+SD++ G AI + I KLR +++ G + P +C+ ++ L T+ALRM K
Sbjct: 229 KYLSGYSDMLGGVAITDSADIVQKLRSVRSMFGNILQPDECWMLDSRLSTVALRMNRQSK 288
Query: 537 SSLIIANWLEKHPKIVEVLHPXLXTHP 617
++ +A L H + +V++P L T P
Sbjct: 289 NAQRLAEALHGHRLLSQVIYPTLFTDP 315
>UniRef50_A6GRN0 Cluster: Cystathionine beta-lyase; n=1; Limnobacter
sp. MED105|Rep: Cystathionine beta-lyase - Limnobacter
sp. MED105
Length = 402
Score = 130 bits (314), Expect = 3e-29
Identities = 75/204 (36%), Positives = 107/204 (52%), Gaps = 2/204 (0%)
Frame = +3
Query: 18 ALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWIET 197
A L GDH + ++VYG L R + + G+ + D N VK ++ NT ++W E
Sbjct: 102 ACLKSGDHWLIPENVYGPVQALARNLYADYGVEFSEYDPCNAASVKAGLRTNTTLVWTEA 161
Query: 198 PTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNGHS 377
P + +V D++AIV +A+ G +DNT+ KP + G D + +LTKY GH+
Sbjct: 162 PGSLTFEVPDLQAIVALAKPHG-ARTGIDNTWAAGIAYKPFEHGFDFSVQALTKYQCGHA 220
Query: 378 DVIMGAAIVND-KAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLIIA 554
DV+MGA + N+ KA D L +G+ SP DC V R L TL LR K+ L +A
Sbjct: 221 DVLMGAVLSNNTKAFAD-LERKNRILGLGVSPADCDLVLRGLLTLHLRYRQQAKNGLQVA 279
Query: 555 NWLEKHPKIVEVLHPXLXTHP-HT 623
L+ HP + VLHP P HT
Sbjct: 280 TALKAHPAVARVLHPEFPECPGHT 303
>UniRef50_UPI00015BB00D Cluster: cystathionine gamma-synthase; n=1;
Ignicoccus hospitalis KIN4/I|Rep: cystathionine
gamma-synthase - Ignicoccus hospitalis KIN4/I
Length = 387
Score = 130 bits (313), Expect = 4e-29
Identities = 72/206 (34%), Positives = 114/206 (55%), Gaps = 1/206 (0%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNI-EKVKNAMQENTK 179
++ +ALL G +V++ D+YG + + GI D + E V + +NT
Sbjct: 87 SSAAMALLKPGSKLVTTKDIYGTSYEFFTTFLRSYGIEV---DERGVGEGVLERIDKNTD 143
Query: 180 MIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTK 359
++++ET +NPLL V ++ I K G ++V DNTF TP PL GA V++S +K
Sbjct: 144 VVFVETISNPLLIVPPVDEIAKACEEVGAKLIV-DNTFATPINFLPLKVGAYGVVHSASK 202
Query: 360 YMNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKS 539
Y+ GH+DV+ G NDK L+ ++ +G +P P YF+ R LKTL +R+ + ++
Sbjct: 203 YLAGHNDVLGGIFATNDKKFALNLKNVRRMLGGIPDPQQAYFIIRGLKTLHVRVAYQNEA 262
Query: 540 SLIIANWLEKHPKIVEVLHPXLXTHP 617
+L IA +L HPK+ V +P L HP
Sbjct: 263 ALRIAKFLRDHPKVERVYYPCLEEHP 288
>UniRef50_Q13Z52 Cluster: Cystathionine beta-lyase; n=2;
Burkholderia|Rep: Cystathionine beta-lyase -
Burkholderia xenovorans (strain LB400)
Length = 394
Score = 130 bits (313), Expect = 4e-29
Identities = 67/199 (33%), Positives = 111/199 (55%)
Frame = +3
Query: 21 LLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWIETP 200
L+ GD ++ D+VY + G++ + + + + ++ NT++IW+E P
Sbjct: 100 LVKAGDDVLIPDNVYSPNRDHGDWLARDFGVSVRYYNPMIGAGIADLIRPNTRLIWLEAP 159
Query: 201 TNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNGHSD 380
+ ++V D+ AI +AR+ +++ +DNT+ +P D G DI + +LTKY +G D
Sbjct: 160 GSVTMEVADVPAITAVARAH-NVVTAIDNTWSAGLGFRPFDHGVDISVQALTKYQSGGGD 218
Query: 381 VIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLIIANW 560
V+MGA I D+ + KL+ + MGI S DC + RSL T+ LR E H +++L +A W
Sbjct: 219 VLMGATITVDRELHLKLKAARMRMGIGVSSDDCSLILRSLPTMQLRFEQHDRAALGLARW 278
Query: 561 LEKHPKIVEVLHPXLXTHP 617
L+ P+I VLHP L P
Sbjct: 279 LKTRPEIATVLHPALPDCP 297
>UniRef50_A7H1V2 Cluster: Cystathionine beta-lyase; n=15;
Campylobacter|Rep: Cystathionine beta-lyase -
Campylobacter jejuni subsp. doylei 269.97
Length = 387
Score = 130 bits (313), Expect = 4e-29
Identities = 67/205 (32%), Positives = 116/205 (56%), Gaps = 3/205 (1%)
Frame = +3
Query: 15 VALLNHGD---HIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMI 185
+ LLN+ H + +D +YG + + ++G+ F + V+ ++ NTK+I
Sbjct: 91 MVLLNYASKDVHFLITDAIYGPVRTICELFLDKMGVEIDFLK-ADASDVEEKIKPNTKLI 149
Query: 186 WIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYM 365
E+P + L +++D+ + KIA + +I V +DNT+ + Y PL+ G DI + + TKY+
Sbjct: 150 LCESPGSILYEIIDLPKLCKIAHAH-NIPVAIDNTYSSGYFLNPLELGVDISVIAATKYL 208
Query: 366 NGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSL 545
+GHSDV MG ++N+K L A+G SP D Y V R ++TL +RM+ H+KS+
Sbjct: 209 SGHSDVTMGIVVINEKE-WKNFDKLPEALGFTTSPDDAYLVLRGMRTLDVRMKAHEKSAD 267
Query: 546 IIANWLEKHPKIVEVLHPXLXTHPH 620
I +L+ +I + +P L +HP+
Sbjct: 268 EIVEFLQSRKEIKTIFYPKLKSHPN 292
>UniRef50_Q5LWC9 Cluster: Cys/Met metabolism PLP-dependent enzyme
family protein; n=5; cellular organisms|Rep: Cys/Met
metabolism PLP-dependent enzyme family protein -
Silicibacter pomeroyi
Length = 403
Score = 129 bits (311), Expect = 7e-29
Identities = 68/200 (34%), Positives = 113/200 (56%), Gaps = 2/200 (1%)
Frame = +3
Query: 24 LNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWIETPT 203
L+ GDH++ SD Y G L R + R+GI + D +++ V A++ T++I ETP
Sbjct: 101 LSAGDHVIVSDVSYAGVAELARDTLPRMGIAVSTVDMSDLAAVAAAIRPETRLIHTETPV 160
Query: 204 NPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNGHSDV 383
NP+ ++ D+ AI +AR G ++ D TF +P + G D+ M+S+TKY+ GH D
Sbjct: 161 NPIGRLTDLAAISALARQAG-ALLSCDATFASPLGMDTVALGVDLTMHSVTKYICGHGDA 219
Query: 384 IMGAAIVNDKAIGDKLRFLQNAM--GIVPSPIDCYFVNRSLKTLALRMEHHKKSSLIIAN 557
+ G A+ + ++R ++ A+ G V SP + + + R TL LRM+ H + +A
Sbjct: 220 VAG-AVCGRADLVSRMR-VEAAIHHGGVLSPFNAWLIARGAATLPLRMKAHAAGAHAVAE 277
Query: 558 WLEKHPKIVEVLHPXLXTHP 617
WLE P++ V++P L +HP
Sbjct: 278 WLEADPRVGRVIYPGLPSHP 297
>UniRef50_Q11MH2 Cluster: Cys/Met metabolism
pyridoxal-phosphate-dependent enzymes; n=1;
Mesorhizobium sp. BNC1|Rep: Cys/Met metabolism
pyridoxal-phosphate-dependent enzymes - Mesorhizobium
sp. (strain BNC1)
Length = 407
Score = 129 bits (311), Expect = 7e-29
Identities = 70/224 (31%), Positives = 118/224 (52%), Gaps = 1/224 (0%)
Frame = +3
Query: 12 LVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWI 191
L ALL GD ++ + YG T ++++ G+ D + + + T+M+ +
Sbjct: 90 LSALLKAGDRVLVTTSAYGSTRTFCTEMLAAFGVEVALYDPGVASGIGAFLDDRTRMVVV 149
Query: 192 ETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNG 371
E+P + +++ DI AI A + G V+ DNT+ + PLD GADI M +L+K+ G
Sbjct: 150 ESPGSNTMEIQDIPAIAHAAHAWGGC-VLADNTWASALCCNPLDLGADIAMEALSKHAGG 208
Query: 372 HSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLII 551
H+DV++GA + D+A+ +++ + MG+ S D R L+T+ LR+E S+L +
Sbjct: 209 HADVLLGALVTRDEALFRRMKDVSRLMGLGVSADDASLALRGLQTMPLRIEREGASALTL 268
Query: 552 ANWLEKHPKIVEVLHPXLXTHP-HTXXLKNX*RVTRVCSVSNXP 680
A WL P+I VLHP L P H ++ +R+ S+ P
Sbjct: 269 AQWLIARPEIARVLHPALQGDPGHHLWKRDFRGASRLFSIELAP 312
>UniRef50_A0H5P3 Cluster: Cys/Met metabolism
pyridoxal-phosphate-dependent enzymes; n=3; Chloroflexi
(class)|Rep: Cys/Met metabolism
pyridoxal-phosphate-dependent enzymes - Chloroflexus
aggregans DSM 9485
Length = 373
Score = 129 bits (311), Expect = 7e-29
Identities = 71/201 (35%), Positives = 109/201 (54%), Gaps = 1/201 (0%)
Frame = +3
Query: 24 LNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWIETPT 203
L G +V DD Y G L +R + T+ + A E +IW+E+P+
Sbjct: 86 LPSGARVVLPDDCYQGVVGLAMAGAARGRWSVQRIALTDTAAWQQACTE-ADLIWLESPS 144
Query: 204 NPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNGHSDV 383
NPLL V D++ I R G I V VDNTF TP Q+PL+ GA + + S TK++ GHSD+
Sbjct: 145 NPLLTVADLDVICAAPRKPGTI-VAVDNTFATPLNQQPLELGATVSVQSATKFIGGHSDL 203
Query: 384 IMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLIIANWL 563
+ G D+A+ +L + G +P ++ + R +TLALR+E + +++I+A L
Sbjct: 204 LAGVVTTRDEALWQQLHQTRTLAGAIPGTLEAFLAVRGARTLALRLERAQYNAMILAQRL 263
Query: 564 EKHPKIVEVLHPXLXTHP-HT 623
+HP + V +P L +HP HT
Sbjct: 264 LEHPLVTCVRYPGLPSHPTHT 284
>UniRef50_UPI000155C3C4 Cluster: PREDICTED: similar to
cystathionase; n=1; Ornithorhynchus anatinus|Rep:
PREDICTED: similar to cystathionase - Ornithorhynchus
anatinus
Length = 382
Score = 128 bits (310), Expect = 1e-28
Identities = 56/108 (51%), Positives = 76/108 (70%)
Frame = +3
Query: 312 KPLDFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVN 491
+PL GADI MYS TKYMNGHSDV+MG VN + + +L+FLQN++G VPSP DCY N
Sbjct: 27 RPLALGADICMYSATKYMNGHSDVVMGLVSVNSEDLYQRLQFLQNSLGAVPSPFDCYLCN 86
Query: 492 RSLKTLALRMEHHKKSSLIIANWLEKHPKIVEVLHPXLXTHPHTXXLK 635
R LKTL +RM+ H ++ L +A +LE P++ +V+ P L +HP +K
Sbjct: 87 RGLKTLQIRMKQHFQNGLAVAKYLESDPRVEKVIFPGLPSHPQHELVK 134
>UniRef50_Q82YZ5 Cluster: Cystathionine gamma-synthase, putative;
n=1; Enterococcus faecalis|Rep: Cystathionine
gamma-synthase, putative - Enterococcus faecalis
(Streptococcus faecalis)
Length = 395
Score = 128 bits (310), Expect = 1e-28
Identities = 62/199 (31%), Positives = 112/199 (56%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
+ TL LL GDH++ + +YG + + Q + + G++ T D E++ +QENTK+
Sbjct: 90 SATLFTLLQQGDHVLMVNTIYGESVSFV-QYLEKFGVSLTKVDVAETEELFQFVQENTKV 148
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
I+ E+P++ +++D+E I +A+ G V+DNT+ +P Q PL D+V++S +KY
Sbjct: 149 IYFESPSSQKFELLDLEKITALAQKIG-AYTVIDNTWASPLFQHPLCHNVDLVIHSCSKY 207
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
+ GHSD++ GA I + A+G V SP + + R ++T+ +R+ H ++
Sbjct: 208 IGGHSDIVAGAVIGKAALVDQIFEHGHQALGAVNSPFNSWLALRGIRTMPVRLAHQSQAI 267
Query: 543 LIIANWLEKHPKIVEVLHP 599
+ L+K P+I + HP
Sbjct: 268 QTVLLALQKDPRISRLYHP 286
>UniRef50_Q2JBH0 Cluster: O-succinylhomoserine sulfhydrylase; n=1;
Frankia sp. CcI3|Rep: O-succinylhomoserine sulfhydrylase
- Frankia sp. (strain CcI3)
Length = 409
Score = 128 bits (309), Expect = 1e-28
Identities = 65/201 (32%), Positives = 110/201 (54%)
Frame = +3
Query: 15 VALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWIE 194
+ LL GDH++ ++ V+G T RL + R G+ TT T+ AM+ T+M+ +E
Sbjct: 104 LGLLRGGDHVLLAEGVFGTTTRLYAHYLDRFGVMTTVVPVTDPAAWARAMRAQTRMLVVE 163
Query: 195 TPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNGH 374
+PTNP++ V DI + ++A + G +++VDNT TP Q+P+ FGAD+V++S KY++G
Sbjct: 164 SPTNPVMAVADIRYLAELAHAAG-ALLLVDNTLCTPVFQQPIVFGADLVLHSAGKYIDGQ 222
Query: 375 SDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLIIA 554
G + + +L + G SP + + +SL+TL +RM H ++ ++A
Sbjct: 223 GR-CGGGVVAGRAGLISELHGVLRTAGPSLSPFNAWIFLKSLETLPVRMRAHDANTAVVA 281
Query: 555 NWLEKHPKIVEVLHPXLXTHP 617
WL P + V + HP
Sbjct: 282 AWLADQPDVRAVHYTGSADHP 302
>UniRef50_A4CKV8 Cluster: Cystathionine beta-lyase; n=11;
Bacteroidetes|Rep: Cystathionine beta-lyase -
Robiginitalea biformata HTCC2501
Length = 417
Score = 128 bits (309), Expect = 1e-28
Identities = 76/209 (36%), Positives = 121/209 (57%), Gaps = 4/209 (1%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
T ++ L + GDH+VSS +YGGT L+ + R I +F D T+ E V A+ + T+M
Sbjct: 99 TAVILQLCSSGDHLVSSRTIYGGTYAFLKNFLKRFDIAVSFVDITDPEAVAAAITDKTRM 158
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
I+ E+ +NPLL+V DI + K+A RG I +VVDNTF +P P GA IV++SLTK+
Sbjct: 159 IYCESVSNPLLEVADIPTLAKLANDRG-IRLVVDNTF-SPLSLSPARLGAHIVVHSLTKF 216
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNAMG-IVPSPID---CYFVNRSLKTLALRMEHH 530
+NG SD + G A+ D L+ + + G ++ S +D + ++L+TL LR+ H
Sbjct: 217 INGSSDAVAG-AVCADSDFCLALKDVNDGAGMLLGSTLDSLRAASILKNLRTLHLRIRQH 275
Query: 531 KKSSLIIANWLEKHPKIVEVLHPXLXTHP 617
++ +A + + V++P L +HP
Sbjct: 276 SSNAAYLAGKFREAG--LRVVYPGLESHP 302
>UniRef50_Q7X1G1 Cluster: Lfe147p1; n=2; Leptospirillum|Rep:
Lfe147p1 - Leptospirillum ferrooxidans
Length = 321
Score = 127 bits (306), Expect = 3e-28
Identities = 71/206 (34%), Positives = 114/206 (55%), Gaps = 4/206 (1%)
Frame = +3
Query: 12 LVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNI---EKVKNAMQENTKM 182
L+ L I +YGGT + Q + G + D E++ + +T
Sbjct: 21 LIHLAKKHPEIAFPKVLYGGTRAFIEQYLIPSGCLIHWFDPREEGWDEELSRRLSPDTGA 80
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
I+ ETP+NP++ V+D+E + A+ G +VV DNTF TP LQKPL GADIV++S TKY
Sbjct: 81 IFAETPSNPVMTVIDLEKLSSAAKKVGAPLVV-DNTFATPILQKPLVLGADIVVHSATKY 139
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNA-MGIVPSPIDCYFVNRSLKTLALRMEHHKKS 539
+ GH D ++G + ++ D+L F + + +G SP + + + R +KTL LRM+ H +
Sbjct: 140 LGGHGD-LLGGTVTGKASLIDRLSFEEGSYLGATLSPFNAWLLLRGMKTLPLRMDAHCRG 198
Query: 540 SLIIANWLEKHPKIVEVLHPXLXTHP 617
++++A +L HP + V +P L P
Sbjct: 199 AMMVAEFLSGHPGVKSVHYPGLSKDP 224
>UniRef50_P43623 Cluster: Putative cystathionine beta-lyase; n=11;
cellular organisms|Rep: Putative cystathionine
beta-lyase - Saccharomyces cerevisiae (Baker's yeast)
Length = 340
Score = 126 bits (305), Expect = 4e-28
Identities = 67/202 (33%), Positives = 117/202 (57%)
Frame = +3
Query: 12 LVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWI 191
L+AL GDHI+ +D VY T L ++++ G+ T + D + + ++ ++ NT +I++
Sbjct: 94 LLALSKAGDHILMTDSVYVPTRMLCDGLLAKFGVETDYYDPSIGKDIEKLVKPNTTVIFL 153
Query: 192 ETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNG 371
E+P + ++V DI A+V +A+ G I ++DNT+ TP G DI + + TKY+ G
Sbjct: 154 ESPGSGTMEVQDIPALVSVAKKHG-IKTILDNTWATPLFFDAHAHGIDISVEAGTKYLGG 212
Query: 372 HSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLII 551
HSD+++G A N++ LR +AM ++P DC R ++TL LR++ ++ +L +
Sbjct: 213 HSDLLIGLASANEEC-WPLLRSTYDAMAMLPGAEDCQLALRGMRTLHLRLKEVERKALDL 271
Query: 552 ANWLEKHPKIVEVLHPXLXTHP 617
A WL ++ +VLHP P
Sbjct: 272 AAWLGNRDEVEKVLHPAFEDCP 293
>UniRef50_A3X9V5 Cluster: Cystathionine gamma-synthase; n=12;
Rhodobacteraceae|Rep: Cystathionine gamma-synthase -
Roseobacter sp. MED193
Length = 390
Score = 126 bits (304), Expect = 5e-28
Identities = 68/197 (34%), Positives = 115/197 (58%), Gaps = 2/197 (1%)
Frame = +3
Query: 30 HGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQ-ENTKMIWIETPTN 206
+G ++ +Y GT + +R +R I D ++I ++ ++++IETP+N
Sbjct: 104 NGGAVIVQSGIYWGTTKWIRDFCTRRDIALHEVDASDIGALQAVCAVHQAQLLFIETPSN 163
Query: 207 PLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNGHSDVI 386
P LK VDI+A A++ G +VV D+T TP L +PL+ GADIVM+S TK +NGHSDV+
Sbjct: 164 PWLKTVDIKAAKACAQTAGASLVV-DSTAATPLLTRPLEMGADIVMHSATKVINGHSDVL 222
Query: 387 MGAAIVNDKA-IGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLIIANWL 563
G + + + + +N G V P + + + RS++TL LR+E +++ +A +L
Sbjct: 223 GGVLSTRLRTPLWEAICMDRNEAGAVMGPFEAWLLVRSMRTLPLRVEKMCANAMAVAEFL 282
Query: 564 EKHPKIVEVLHPXLXTH 614
HP++ +VL+P L +H
Sbjct: 283 ASHPEVEDVLYPGLPSH 299
>UniRef50_A5G088 Cluster: Cystathionine gamma-synthase; n=1;
Acidiphilium cryptum JF-5|Rep: Cystathionine
gamma-synthase - Acidiphilium cryptum (strain JF-5)
Length = 416
Score = 124 bits (300), Expect = 2e-27
Identities = 77/207 (37%), Positives = 116/207 (56%), Gaps = 12/207 (5%)
Frame = +3
Query: 6 TTLVALLNHGDHIVSSDDVYGGTNRLLRQVVS-RLGIN-TTFTDFTNIEKVKNAM----- 164
T L++L+ GD ++ + +YGGT+ LL V++ LG+ D + V+ A
Sbjct: 101 TALLSLVRPGDSVLHTSPLYGGTDGLLTGVMAPELGVRPVAIADALDEGSVREAAAGALA 160
Query: 165 QENTKMIWIETPTNPLLKVVDIEAIVKIAR--SRGDI---IVVVDNTFLTPYLQKPLDFG 329
+WIETP+NPL + DI I ++AR + G +V+VDNTFL P LQ PL G
Sbjct: 161 HGPLAAVWIETPSNPLAGLADIALIARVAREAAAGQARPPVVIVDNTFLGPTLQAPLRHG 220
Query: 330 ADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTL 509
AD+ M SLTKY GHSD ++G AI A+ + LR + MG P + + RS++T+
Sbjct: 221 ADLCMTSLTKYAGGHSD-LLGGAISGATALVEPLRKRRTLMGTHLDPHGSWLLLRSIETM 279
Query: 510 ALRMEHHKKSSLIIANWLEKHPKIVEV 590
LR+E +++ +A +L HPK+ V
Sbjct: 280 GLRVERAGQNAATVARFLAAHPKVSRV 306
>UniRef50_A3U7R8 Cluster: O-acetylhomoserine sulfhydrylase; n=8;
Bacteria|Rep: O-acetylhomoserine sulfhydrylase -
Croceibacter atlanticus HTCC2559
Length = 438
Score = 124 bits (300), Expect = 2e-27
Identities = 64/132 (48%), Positives = 87/132 (65%)
Frame = +3
Query: 6 TTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMI 185
TTL+ LL GDHIV+S+ +YGGT LL+ + R GI TTF D N E K A +ENT+
Sbjct: 91 TTLLTLLKAGDHIVASNSLYGGTYNLLKVTLPRFGITTTFVDPQNPENFKKASKENTRAY 150
Query: 186 WIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYM 365
+IE+ NP L V+DIEAI I + ++VDNT TP L P+++GA+IV++SLTKY+
Sbjct: 151 FIESLGNPKLDVLDIEAI-SIEAKAYKVPLIVDNTVATPALLNPINYGANIVIHSLTKYI 209
Query: 366 NGHSDVIMGAAI 401
NG+ + G I
Sbjct: 210 NGNGTALGGVII 221
Score = 42.7 bits (96), Expect = 0.008
Identities = 18/61 (29%), Positives = 35/61 (57%)
Frame = +3
Query: 453 GIVPSPIDCYFVNRSLKTLALRMEHHKKSSLIIANWLEKHPKIVEVLHPXLXTHPHTXXL 632
G SP + + + + L+TL +R+E H K++L +A WL++ ++ V +P L + +
Sbjct: 270 GAALSPFNAFQILQGLETLEIRLEKHSKNALNLATWLQEQEEVTWVNYPGLKSSKYNSLA 329
Query: 633 K 635
K
Sbjct: 330 K 330
>UniRef50_Q9RSD8 Cluster: O-acetylhomoserine
(Thiol)-lyase/O-acetylserine (Thiol)-lyase; n=2;
Deinococcus|Rep: O-acetylhomoserine
(Thiol)-lyase/O-acetylserine (Thiol)-lyase - Deinococcus
radiodurans
Length = 418
Score = 124 bits (299), Expect = 2e-27
Identities = 70/228 (30%), Positives = 122/228 (53%), Gaps = 24/228 (10%)
Frame = +3
Query: 6 TTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMI 185
T ++++ GDH+VSS ++GG+ +L ++ +GI T + + E+++ AMQ+NT+++
Sbjct: 98 TAILSVCRAGDHVVSSASLFGGSTGMLTNILPLMGITATLVE-GHPEQIRAAMQDNTRLV 156
Query: 186 WIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYM 365
W E +NP V D+EA+ +A RG ++ + + YL +PLD GADIV SLTK+
Sbjct: 157 WAEMISNPSGAVADVEALAGVAHERGALLAIDNTCGGVGYLCRPLDHGADIVSQSLTKWA 216
Query: 366 NGHSDVIMGAAIVN-------------------DKAIGDKLRFLQ-----NAMGIVPSPI 473
GH V+ G+ V ++ D L + Q + +G+ +P
Sbjct: 217 GGHGSVMGGSVTVGTQHDLSRNPIYAGGENSLLEQRGADALAWRQRWFGAHQLGMTLAPH 276
Query: 474 DCYFVNRSLKTLALRMEHHKKSSLIIANWLEKHPKIVEVLHPXLXTHP 617
+ + + L+TL LR++ S+L +A WL +HP++ V + L HP
Sbjct: 277 SAFLIAQGLETLGLRLQRESDSALALARWLGQHPRVGGVSYAGLPGHP 324
>UniRef50_Q26GX1 Cluster: Cys/Met metabolism PLP-dependent enzyme;
n=2; Flavobacteria|Rep: Cys/Met metabolism PLP-dependent
enzyme - Flavobacteria bacterium BBFL7
Length = 423
Score = 123 bits (297), Expect = 4e-27
Identities = 74/206 (35%), Positives = 122/206 (59%), Gaps = 10/206 (4%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTT-----FTDFTNIEKVKNA-M 164
+T L+ L G ++ S YGGT+ + + + GI++ + I+ VK+A
Sbjct: 101 STVLMEFLEPGQVLLYSSPTYGGTDHFINHFLPKYGIHSLGFKSGMSKEEIIKLVKDAGY 160
Query: 165 QENTKMIWIETPTNPLLKVVDIEAIVKIAR--SRGD--IIVVVDNTFLTPYLQKPLDFGA 332
+ ++ IETP NP ++DIE +IA S D ++V VDNT++ P Q PL GA
Sbjct: 161 ADKIALMHIETPANPTNALIDIEMCREIADHFSTSDKKVLVGVDNTYMGPLWQHPLQLGA 220
Query: 333 DIVMYSLTKYMNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLA 512
DIVMYS TKY+ GHSD+I GA + N + I +++ L+ +G + SP + + RSL+TL
Sbjct: 221 DIVMYSATKYIGGHSDLIAGAVLGNAE-IMHRVKVLRTFLGNMASPHTGWMLMRSLETLK 279
Query: 513 LRMEHHKKSSLIIANWLEKHPKIVEV 590
+RME +++++ +A++L+ H KI ++
Sbjct: 280 IRMEQQQRNAIEVAHFLKDHEKITKL 305
>UniRef50_A5G8H3 Cluster: O-acetylhomoserine
aminocarboxypropyltransferase; n=3; Geobacter|Rep:
O-acetylhomoserine aminocarboxypropyltransferase -
Geobacter uraniumreducens Rf4
Length = 428
Score = 123 bits (296), Expect = 5e-27
Identities = 76/228 (33%), Positives = 125/228 (54%), Gaps = 22/228 (9%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
TT ++ ++ GD I++S ++GGT L R +S GI+TTF D T++ V+N + + T++
Sbjct: 104 TTAVMTIVRSGDEILASSSLFGGTFSLFRDTLSGYGISTTFVDPTDLAAVRNGINDRTRL 163
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
+++ET NP + V DI AI IAR+ G I ++VD T TP L + D GADIV++S +K+
Sbjct: 164 VFVETIGNPKMDVPDIPAIALIARAAG-IPLLVDATVTTPCLARGSDLGADIVIHSTSKF 222
Query: 363 MNGHSDVIMGAAI-------VNDK--------------AIGDKLR-FLQNAMGIVPSPID 476
+NG I G I +DK A + R + G +P++
Sbjct: 223 INGTGSAIGGVIIDLGRFDWQSDKFPHFEPFHKKYRAFAFTARARKLIHKDFGACAAPMN 282
Query: 477 CYFVNRSLKTLALRMEHHKKSSLIIANWLEKHPKIVEVLHPXLXTHPH 620
+ + ++TL+LRME H ++ +A +L+ H ++ V +P L PH
Sbjct: 283 SFLLAEGVETLSLRMERHCANAQKLAQFLKAHDRVRWVNYPGLEDSPH 330
>UniRef50_Q89V23 Cluster: O-acetylhomoserine sulfhydrylase; n=13;
Bacteria|Rep: O-acetylhomoserine sulfhydrylase -
Bradyrhizobium japonicum
Length = 431
Score = 121 bits (292), Expect = 1e-26
Identities = 60/130 (46%), Positives = 85/130 (65%)
Frame = +3
Query: 12 LVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWI 191
+ LLN GDHIV+S +YGGT LL + R GI TTF +++ ++A++ NTK++
Sbjct: 96 IATLLNAGDHIVASSSLYGGTINLLAHTLPRFGITTTFVKPRDLDAFRSAIKPNTKLVIG 155
Query: 192 ETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNG 371
ET NP L+V+DI + IA I +++DNTF TPYL +P++ GADIVM+S TK++ G
Sbjct: 156 ETIGNPGLEVLDIPKVAAIAH-EAKIPLLIDNTFATPYLSRPIELGADIVMHSATKWIGG 214
Query: 372 HSDVIMGAAI 401
H I GA I
Sbjct: 215 HGIAIGGAII 224
Score = 33.1 bits (72), Expect = 6.7
Identities = 15/54 (27%), Positives = 30/54 (55%)
Frame = +3
Query: 453 GIVPSPIDCYFVNRSLKTLALRMEHHKKSSLIIANWLEKHPKIVEVLHPXLXTH 614
G SP + + + + ++TL +RM+ H +++ + L+ + + VLHP L H
Sbjct: 274 GACLSPTNAFQLLQGVETLGVRMDRHMQNTHSVLEALKSNKAVDWVLHPSLEDH 327
>UniRef50_Q5NQQ3 Cluster: Cystathionine beta-lyase; n=41;
Proteobacteria|Rep: Cystathionine beta-lyase - Zymomonas
mobilis
Length = 682
Score = 121 bits (292), Expect = 1e-26
Identities = 66/202 (32%), Positives = 109/202 (53%)
Frame = +3
Query: 12 LVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWI 191
L++ L GD ++ D Y T V+ GIN T+ D + ++ T+ I++
Sbjct: 379 LLSALEAGDELLMVDSCYEPTRVFCDTVLKAQGINVTYYDPLIGQDIEQLFTPQTRAIFM 438
Query: 192 ETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNG 371
E+P + +V DI I ++A R I ++DNT+ TP ++ G D+ + + TKY+ G
Sbjct: 439 ESPGSLTFEVQDIPGICEVAH-RYSITTILDNTWATPLFFPAIERGVDLSVMACTKYITG 497
Query: 372 HSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLII 551
HSD +MG+ I DKL+ + N G SP D + L+TL +R++ H+K++L +
Sbjct: 498 HSDTMMGSVTAIPSHI-DKLKRISNLFGQYVSPDDANSALKGLRTLEVRLKAHEKNALKV 556
Query: 552 ANWLEKHPKIVEVLHPXLXTHP 617
A WL + P++ VLHP L + P
Sbjct: 557 AKWLSEQPEVAWVLHPALSSCP 578
>UniRef50_Q1V2M7 Cluster: Cystathionine beta-lyase; n=2; Candidatus
Pelagibacter ubique|Rep: Cystathionine beta-lyase -
Candidatus Pelagibacter ubique HTCC1002
Length = 391
Score = 121 bits (292), Expect = 1e-26
Identities = 63/197 (31%), Positives = 113/197 (57%)
Frame = +3
Query: 9 TLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIW 188
++ +++ GD I+ +D Y T L + + + + F D +++ ++ A+ + TK+I+
Sbjct: 94 SIFSIVRPGDEIIVADPTYSPTRILTQDFLKEFNVKSVFYDPHDLKTLEKAITKKTKLIF 153
Query: 189 IETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMN 368
+E P + D+ IV IA+ + I V+DNT+ TPY KP+ G D+ + S TKY +
Sbjct: 154 VENPGSNTFDFQDLGKIVSIAK-KNKIFSVIDNTWGTPYFLKPIKLGFDMSIVSATKYYS 212
Query: 369 GHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLI 548
GHSDV+ G+ VN KA ++ G+ P D Y + R L+TL +R++ H+KS+
Sbjct: 213 GHSDVMGGSLAVNKKAF-KQVDKANKITGLRLGPDDAYLITRGLRTLDVRLDKHEKSAKQ 271
Query: 549 IANWLEKHPKIVEVLHP 599
+A +L + K +++L+P
Sbjct: 272 VAEFLSNY-KNIKLLYP 287
>UniRef50_Q8NM00 Cluster: Cystathionine beta-lyases/cystathionine
gamma-synthases; n=1; Corynebacterium glutamicum|Rep:
Cystathionine beta-lyases/cystathionine gamma-synthases
- Corynebacterium glutamicum (Brevibacterium flavum)
Length = 382
Score = 121 bits (291), Expect = 2e-26
Identities = 66/204 (32%), Positives = 108/204 (52%)
Frame = +3
Query: 6 TTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMI 185
T++ L+ G +V Y G + ++ +R + D N E+V A Q ++
Sbjct: 86 TSIADLVPTGGTVVLPKAAYYGVTNIFARMEARGRLKVRTVDADNTEEVIAAAQ-GADVV 144
Query: 186 WIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYM 365
W+E+ NP + V DI AIV R G ++ VVD TF TP Q+PL+ GADIV+YS TK +
Sbjct: 145 WVESIANPTMVVADIPAIVDGVRGLG-VLTVVDATFATPLRQRPLELGADIVLYSATKLI 203
Query: 366 NGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSL 545
GHSD+++G A+ + L ++ G VP ++ + R L +LA+R++ + ++
Sbjct: 204 GGHSDLLLGVAVCKSEHHAQFLATHRHDHGSVPGGLEAFLALRGLYSLAVRLDRAESNAA 263
Query: 546 IIANWLEKHPKIVEVLHPXLXTHP 617
++ L HP + V +P L P
Sbjct: 264 ELSRRLNAHPSVTRVNYPGLPDDP 287
>UniRef50_Q2K0N3 Cluster: Cystathionine gamma-synthase protein; n=7;
Alphaproteobacteria|Rep: Cystathionine gamma-synthase
protein - Rhizobium etli (strain CFN 42 / ATCC 51251)
Length = 390
Score = 121 bits (291), Expect = 2e-26
Identities = 63/201 (31%), Positives = 115/201 (57%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
++ +++ + GD IV+ VY RL ++ R+ I T+ D + E V A+ K+
Sbjct: 92 SSAVLSFVEPGDRIVAVKHVYPDAFRLFGTILKRMKIEVTYVDGRDEEAVARALP-GAKL 150
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
+++E+PT+ +++ D+ A+ +A+ G + ++DN++ +P+ Q+PL G D+V++S +KY
Sbjct: 151 LYLESPTSWVMEAHDVGALAALAKRHG-AVSMIDNSWASPFFQRPLTLGVDLVIHSASKY 209
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
+ GHSDV+ G + + I +G SP D + + R L+TL LRM+ H+ S+
Sbjct: 210 LGGHSDVVAGVVAGSKEMIARVKAEAYPYLGGKLSPFDAWLLIRGLRTLPLRMKAHEASA 269
Query: 543 LIIANWLEKHPKIVEVLHPXL 605
L IA L++ + V HP L
Sbjct: 270 LEIARRLQRLEVVETVCHPGL 290
>UniRef50_Q4AEY8 Cluster: Cystathionine gamma-synthase; n=1;
Chlorobium phaeobacteroides BS1|Rep: Cystathionine
gamma-synthase - Chlorobium phaeobacteroides BS1
Length = 245
Score = 121 bits (291), Expect = 2e-26
Identities = 57/155 (36%), Positives = 95/155 (61%)
Frame = +3
Query: 18 ALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWIET 197
ALL GDH+++S ++G + L+ ++ GI F ++ +NA NTKM+++ET
Sbjct: 93 ALLKKGDHLLASSSIFGSSRHLIENILPNWGIEHEFVGIKDMHAWENAFHPNTKMVFVET 152
Query: 198 PTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNGHS 377
P NP L ++D++ + ++ +G I+VVDN F TPYLQ+PL FGAD+V++S TKY++G
Sbjct: 153 PANPTLDLIDLKYLAELCYQKG-AILVVDNCFATPYLQQPLSFGADLVVHSATKYIDGQG 211
Query: 378 DVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCY 482
V+ G + + I +F+Q + G SP + +
Sbjct: 212 RVLGGVIVGSKTKIEICAQFIQKS-GPSLSPFNAW 245
>UniRef50_Q98KA4 Cluster: Probable cystathionine/methionine
gamma-synthase/lyase; n=3; Alphaproteobacteria|Rep:
Probable cystathionine/methionine gamma-synthase/lyase -
Rhizobium loti (Mesorhizobium loti)
Length = 371
Score = 120 bits (290), Expect = 3e-26
Identities = 70/205 (34%), Positives = 108/205 (52%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
++ ALL GD ++ D Y T + + + LGI D + + +
Sbjct: 82 SSVFFALLKSGDRVLLPADGYHATRAMAERFLKPLGITC---DTRPTPTFLDGGFKGYSL 138
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
+++ETP+NP L + DI AI K +G +VV DNT +TP+ Q+PLDFGADIV+ + TK
Sbjct: 139 VFVETPSNPRLDICDISAIAKAVHEQGGALVV-DNTTMTPFGQRPLDFGADIVVSADTKA 197
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
+NGHSDV+ G D I K+ + G +P P + + V+R L+TL +R + S+
Sbjct: 198 VNGHSDVLFGHVASRDADIISKVTNWRAMAGGIPGPFEAWLVHRGLETLEVRFDRMCSSA 257
Query: 543 LIIANWLEKHPKIVEVLHPXLXTHP 617
IA L++H + + P L P
Sbjct: 258 ETIAQRLKEHRAVRGLRFPGLNGDP 282
>UniRef50_Q67VG6 Cluster: Putative O-succinylhomoserine
(Thiol)-lyase; n=4; Oryza sativa|Rep: Putative
O-succinylhomoserine (Thiol)-lyase - Oryza sativa subsp.
japonica (Rice)
Length = 425
Score = 119 bits (286), Expect = 8e-26
Identities = 66/212 (31%), Positives = 116/212 (54%), Gaps = 9/212 (4%)
Frame = +3
Query: 9 TLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAM-QENTKMI 185
TL+A++ G H+V++ D Y +R +S++GI TTF D ++E +++ + Q N M
Sbjct: 116 TLLAVVPPGGHVVATTDCYSEARAFIRDRLSKMGIRTTFVDLDDMEALQSVLDQGNVTMF 175
Query: 186 WIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYM 365
+ ++ TNP LK VD+ + ++ RG +V +D+T +P QKPL GAD+V++S + +
Sbjct: 176 YADSLTNPHLKCVDVRRVAELCHQRG-ALVCIDSTLASPINQKPLTLGADVVLHSHHQVI 234
Query: 366 NGHSDVI--------MGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRM 521
+ MG +N + + + P ++ Y + R LKT+ALR+
Sbjct: 235 GAGWETPWVTDFTTGMGVGFLNWHPVDITSARGRLWTPLSPPDLEAYMIIRGLKTMALRV 294
Query: 522 EHHKKSSLIIANWLEKHPKIVEVLHPXLXTHP 617
E +++L +A LE+HPK+ V +P L + P
Sbjct: 295 EAQNRTALRVARLLERHPKVERVNYPWLESSP 326
>UniRef50_Q7M844 Cluster: O-ACETYLHOMOSERINE (THIOL)-LYASE; n=1;
Wolinella succinogenes|Rep: O-ACETYLHOMOSERINE
(THIOL)-LYASE - Wolinella succinogenes
Length = 422
Score = 93.5 bits (222), Expect(2) = 1e-25
Identities = 44/138 (31%), Positives = 80/138 (57%)
Frame = +3
Query: 21 LLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWIETP 200
L G++I+++ +YGGT +SR GI F D + ++ + + ++ ++ E+
Sbjct: 93 LAQSGENIIATTQLYGGTLNQFTHTLSRFGIEVRFFDGNHPQEARALIDSKSRALFFESL 152
Query: 201 TNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNGHSD 380
TNP + V +I+ + KIA G I+ +VDNT TP + +P++ G D+V++S +KYM G
Sbjct: 153 TNPSIDVPEIDTLAKIADEYG-IVSIVDNTVATPAICRPIEHGVDVVVHSASKYMGGQG- 210
Query: 381 VIMGAAIVNDKAIGDKLR 434
+ +G +V + +KLR
Sbjct: 211 LAIGGVLVESARVAEKLR 228
Score = 46.0 bits (104), Expect(2) = 1e-25
Identities = 19/52 (36%), Positives = 33/52 (63%)
Frame = +3
Query: 450 MGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLIIANWLEKHPKIVEVLHPXL 605
+G SP D + + ++TL++RM H S++ IA++L+ HPK+ V +P L
Sbjct: 268 IGATLSPFDSWLFIQGIETLSVRMREHSLSAMKIAHYLQNHPKVQAVYYPGL 319
>UniRef50_Q1GVW8 Cluster: Cystathionine gamma-lyase; n=15;
Bacteria|Rep: Cystathionine gamma-lyase - Sphingopyxis
alaskensis (Sphingomonas alaskensis)
Length = 430
Score = 118 bits (284), Expect = 1e-25
Identities = 74/210 (35%), Positives = 120/210 (57%), Gaps = 18/210 (8%)
Frame = +3
Query: 6 TTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFT------NIEKVKN--- 158
T L+AL+ D IV S +Y T L+ +++SR G++ F DF +I+ +
Sbjct: 113 TLLLALVGQNDVIVHSGPLYAATETLIARILSRFGVS--FVDFPAGASRDDIDVILARAQ 170
Query: 159 --AMQENTK--MIWIETPTNPLLKVVDIEAIVKIARSRG-----DIIVVVDNTFLTPYLQ 311
A Q+ K ++++E+P NP +VD+EA V+ AR + +DNTFL P Q
Sbjct: 171 ALASQKGGKVALVYLESPANPTNALVDVEA-VRAARDTAFPGEQKPAIAIDNTFLGPLWQ 229
Query: 312 KPLDFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVN 491
+PL GA++V+YSLTKY GHSD++ G + D+ + D +R ++N +G + P + +
Sbjct: 230 QPLKQGAELVIYSLTKYAGGHSDLVAG-GVSGDQRLLDIIRPMRNTIGTICDPNTAWMLL 288
Query: 492 RSLKTLALRMEHHKKSSLIIANWLEKHPKI 581
RSL+TL LRM +++L + +L HPK+
Sbjct: 289 RSLETLELRMRRAGENALKVCTFLRDHPKV 318
>UniRef50_Q7WM51 Cluster: Cystathionase beta-lyase; n=3;
Proteobacteria|Rep: Cystathionase beta-lyase -
Bordetella bronchiseptica (Alcaligenes bronchisepticus)
Length = 408
Score = 118 bits (283), Expect = 2e-25
Identities = 65/202 (32%), Positives = 114/202 (56%)
Frame = +3
Query: 12 LVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWI 191
L++ L GDH++ SD VY +L+ ++ I TF + V++ ++ T+MI+
Sbjct: 100 LLSYLKPGDHLLMSDAVYEPARKLVHSFLAPYQIRCTFFAADGSD-VQDKLEPATRMIYA 158
Query: 192 ETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNG 371
E P + + ++ D+ + +IA G ++ DNT+ + +PL GAD+ + + TKY++G
Sbjct: 159 ECPGSLVYEMCDLPRLAEIAHRHGALLAC-DNTWGSGCQYRPLALGADVSIMAATKYLSG 217
Query: 372 HSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLII 551
HSDV+MG + +A L +A G+ SP D Y V R +++LA R+ H++ +L I
Sbjct: 218 HSDVMMG-TVATTEAAWPALSERSDAFGMTVSPDDAYLVLRGIRSLAARLAMHERHALRI 276
Query: 552 ANWLEKHPKIVEVLHPXLXTHP 617
A +L++ P++ V P L HP
Sbjct: 277 AGYLQERPEVRTVFCPALPGHP 298
>UniRef50_Q8FRS9 Cluster: O-acetylhomoserine sulfhydrylase; n=8;
Bacteria|Rep: O-acetylhomoserine sulfhydrylase -
Corynebacterium efficiens
Length = 438
Score = 91.5 bits (217), Expect(2) = 2e-25
Identities = 51/138 (36%), Positives = 79/138 (57%), Gaps = 1/138 (0%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNI-EKVKNAMQENTK 179
T ++ L G H+V+S +YGGT L + RLGI TF + + E + A+++NT
Sbjct: 99 TAAILNLGGAGSHVVTSPRLYGGTETLFLVTLKRLGIEFTFVENPDDPESWQAAVRDNTI 158
Query: 180 MIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTK 359
+ ET NP V+DI A+ ++A R + ++VDNT T L +P++ GADIV+ SLTK
Sbjct: 159 AFFGETFANPQADVLDIPAVSEVAH-RNQVPLIVDNTIATAALVRPIELGADIVVASLTK 217
Query: 360 YMNGHSDVIMGAAIVNDK 413
+ G+ + GA + K
Sbjct: 218 FYTGNGSALGGALVDGGK 235
Score = 47.2 bits (107), Expect(2) = 2e-25
Identities = 24/69 (34%), Positives = 37/69 (53%), Gaps = 1/69 (1%)
Frame = +3
Query: 414 AIGDKLRF-LQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLIIANWLEKHPKIVEV 590
A G K R L G PSP + + N+ L TL+LR+E H ++++ +A +L H K+ +V
Sbjct: 270 AFGLKARVGLLRDTGAAPSPFNAWVTNQGLDTLSLRLERHNENAIKVAEFLNNHEKVTKV 329
Query: 591 LHPXLXTHP 617
L P
Sbjct: 330 HFAGLPDSP 338
>UniRef50_A3UCF8 Cluster: Cystathionine beta-lyase; n=1;
Oceanicaulis alexandrii HTCC2633|Rep: Cystathionine
beta-lyase - Oceanicaulis alexandrii HTCC2633
Length = 381
Score = 116 bits (280), Expect = 4e-25
Identities = 68/195 (34%), Positives = 97/195 (49%)
Frame = +3
Query: 33 GDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPL 212
G + +D YG R + + R G+ + D V + + T ++ +E+P +
Sbjct: 96 GMQALITDSAYGPVRRFCDEELPRYGVTPVYYDPRIGAGVAELLDKPTAVVLLESPGSLT 155
Query: 213 LKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNGHSDVIMG 392
+V DI AI AR G + V+D+T+ L PL+ G D +LTKY GHSD +MG
Sbjct: 156 FEVQDIPAIAGAARKAG-VATVIDDTWSAGVLMNPLELGVDYAAQALTKYAGGHSDFLMG 214
Query: 393 AAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLIIANWLEKH 572
+ ++ +L+ G SP D Y R L+TL LR+E S L IA LE H
Sbjct: 215 SVAARGESAA-RLKDKDVLFGGHVSPDDAYLCLRGLRTLLLRIERSGASGLHIARQLEAH 273
Query: 573 PKIVEVLHPXLXTHP 617
PKI VLHP L +HP
Sbjct: 274 PKIARVLHPGLQSHP 288
>UniRef50_UPI0000F2BB70 Cluster: PREDICTED: similar to Chain A,
Crystal Structure Of Human Cystathionine Gamma Lyase;
n=3; Mammalia|Rep: PREDICTED: similar to Chain A,
Crystal Structure Of Human Cystathionine Gamma Lyase -
Monodelphis domestica
Length = 500
Score = 116 bits (278), Expect = 7e-25
Identities = 50/103 (48%), Positives = 70/103 (67%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
T + LL GDHIV +DVYGGTNR R+V + LG+ +F D + +E + A+ TK+
Sbjct: 94 TLNITHLLKAGDHIVCMNDVYGGTNRYFRRVATELGLKISFVDCSKLELLNAAITPETKL 153
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQ 311
+WIETPTNP LKV+DI+ ++ GD+I+VVDNTF++ Y Q
Sbjct: 154 VWIETPTNPGLKVIDIKGCAQVVHKHGDVILVVDNTFMSAYFQ 196
>UniRef50_A7HB44 Cluster: Cys/Met metabolism
pyridoxal-phosphate-dependent protein; n=2;
Anaeromyxobacter|Rep: Cys/Met metabolism
pyridoxal-phosphate-dependent protein - Anaeromyxobacter
sp. Fw109-5
Length = 363
Score = 116 bits (278), Expect = 7e-25
Identities = 56/146 (38%), Positives = 90/146 (61%)
Frame = +3
Query: 180 MIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTK 359
++W+ETP NP ++ DI + AR+ G +VV D TF TP LQ+PL GAD+V +S+TK
Sbjct: 130 VVWLETPKNPTCELQDIASHAARARAAGARLVV-DGTFATPVLQQPLALGADLVYHSMTK 188
Query: 360 YMNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKS 539
++ GHSD + G + D+A+ + LR + G VP ++ + V R ++TL LR+ +
Sbjct: 189 FLAGHSDALGGVLVARDQALAEGLRATRTVTGGVPGALETWLVLRGVRTLGLRVRQQTAN 248
Query: 540 SLIIANWLEKHPKIVEVLHPXLXTHP 617
+ +A +LE+ ++ V HP L +HP
Sbjct: 249 ATRLAAFLER--RVARVWHPSLPSHP 272
>UniRef50_Q59829 Cluster: Putative cystathionine gamma-lyase; n=8;
Actinomycetales|Rep: Putative cystathionine gamma-lyase
- Streptomyces coelicolor
Length = 392
Score = 116 bits (278), Expect = 7e-25
Identities = 68/205 (33%), Positives = 108/205 (52%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
++ L + L GD V DD Y L+R + GI T T + + + + K+
Sbjct: 102 SSVLFSQLRAGDTAVLPDDGYQALP-LVRAQLEAYGIEVR-TAPTGRDAQLDVL-DGAKL 158
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
+WIETP+NP L V D+ +V+ A + G +V VDNT TP Q+PL+ GAD + S TK
Sbjct: 159 LWIETPSNPGLDVCDVRRLVEAAHA-GGALVAVDNTLATPLGQRPLELGADFSVASGTKQ 217
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
+ GH DV++G D +R + +G +P P++ + +RS+ TL LR++ ++
Sbjct: 218 LTGHGDVLLGYVAGRDAGAMAAVRRWRKIVGAIPGPMEAWLAHRSIATLQLRVDRQDSTA 277
Query: 543 LIIANWLEKHPKIVEVLHPXLXTHP 617
L +A L P+I + +P L P
Sbjct: 278 LKVAEALRTRPEITGLRYPGLPDDP 302
>UniRef50_UPI0000E47CE2 Cluster: PREDICTED: similar to cystathionine
beta-lyase; n=2; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to cystathionine beta-lyase -
Strongylocentrotus purpuratus
Length = 392
Score = 115 bits (277), Expect = 1e-24
Identities = 51/136 (37%), Positives = 84/136 (61%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
+ ++A++ GDHI++ D VY G L+ V+ G+ TF +++ + A++ NTK+
Sbjct: 125 SNNILAVVKTGDHIIAPDPVYSGVYAFLKHVIGNYGVEVTFVPSGDLDAYRKAIKPNTKV 184
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
+ ETPTNP++ ++D++A +A+S I + D+TF +P LQ L G DIV S TKY
Sbjct: 185 FYGETPTNPVMSLLDLKAFADLAKSVPGAISMCDSTFASPILQDTLGLGIDIVFQSCTKY 244
Query: 363 MNGHSDVIMGAAIVND 410
M GHSD++ G+ +D
Sbjct: 245 MGGHSDLMGGSMCTSD 260
>UniRef50_Q97MT9 Cluster: O-acetylhomoserine sulfhydrylase; n=4;
Clostridiales|Rep: O-acetylhomoserine sulfhydrylase -
Clostridium acetobutylicum
Length = 409
Score = 115 bits (276), Expect = 1e-24
Identities = 70/217 (32%), Positives = 126/217 (58%), Gaps = 22/217 (10%)
Frame = +3
Query: 21 LLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWIETP 200
+++ GD I++S +YGGT L+ + +G+ F + + + + N + ENTK+++ ET
Sbjct: 92 IVHPGDEIIASTGLYGGTYTLISNL-QNIGVKVIFLEDISKKTLLNNINENTKLVYTETI 150
Query: 201 TNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNGHSD 380
NP L ++DIE++ ++ + +G II +VD+T TPYL P +GAD++++S +KY+NG S+
Sbjct: 151 GNPKLDILDIESVGRVCKEKG-IIFMVDSTISTPYLINPSKYGADVIIHSTSKYINGTSN 209
Query: 381 VIMGAAI--VNDKAIG-------------DKLRF---LQNAMGI----VPSPIDCYFVNR 494
I G + ++K DKL F L++ G+ SP + +
Sbjct: 210 AIGGMIVDCGSEKYKNHRYENFQKYAEKYDKLAFTAKLKSTSGLDIGASMSPFNAFLSLT 269
Query: 495 SLKTLALRMEHHKKSSLIIANWLEKHPKIVEVLHPXL 605
++TL+LRM+ H ++++ IA++LEK K+ V +P L
Sbjct: 270 GIETLSLRMKKHCENAMKIASYLEKSDKVTNVNYPNL 306
>UniRef50_A3VUE2 Cluster: Cystathionine beta-lyase; n=1;
Parvularcula bermudensis HTCC2503|Rep: Cystathionine
beta-lyase - Parvularcula bermudensis HTCC2503
Length = 381
Score = 115 bits (276), Expect = 1e-24
Identities = 67/206 (32%), Positives = 112/206 (54%), Gaps = 1/206 (0%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTD-FTNIEKVKNAMQENTK 179
T +++ + G H++ +D Y T ++ I TT+ D E++ + T+
Sbjct: 82 TLAILSCVTAGGHVLVTDSAYEPTRTFCDGLLRGFDIETTYFDPQAGREEIAALCRPTTQ 141
Query: 180 MIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTK 359
+I+ E+P + +V D+ AIV A G++ V VDNT+ L +PL+ G I + +LTK
Sbjct: 142 LIFCESPGSLTFEVQDLPAIVAGA---GEVPVAVDNTYGAGVLLRPLELGCAISVQALTK 198
Query: 360 YMNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKS 539
Y+ GHSD+++G A+ + K+R + +GI S D +R L+TL R+ H+++
Sbjct: 199 YVGGHSDLLLG-AVATAPRLSAKVRRMARMLGISVSGRDVAMAHRGLRTLHRRLAVHEEN 257
Query: 540 SLIIANWLEKHPKIVEVLHPXLXTHP 617
L +A +LE H I VLHP L +HP
Sbjct: 258 GLGLARFLETHSAIRRVLHPGLDSHP 283
>UniRef50_Q4Q511 Cluster: Cystathionine beta-lyase, putative; n=3;
Leishmania|Rep: Cystathionine beta-lyase, putative -
Leishmania major
Length = 399
Score = 115 bits (276), Expect = 1e-24
Identities = 64/199 (32%), Positives = 113/199 (56%), Gaps = 3/199 (1%)
Frame = +3
Query: 12 LVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTD-FTNIEKVKNAMQE--NTKM 182
L+A N GD+I+ +D VY T L + GI TT+ D ++++ + + NT +
Sbjct: 94 LLATANSGDNILVADAVYLPTRNLCDHFLVTKGITTTYYDPCITADELRELLHQKPNTTV 153
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
I++E+P + ++ D+ I +AR ++ ++DNT+ TP L G DI + + TKY
Sbjct: 154 IFMESPGSQTFEIQDVPMICAVAREF-NVTTIIDNTWATPIFFDALGIGCDISVEAGTKY 212
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
+ GHSD+++G N+K KLR + + VPS DCY R L+T+ +R++ ++
Sbjct: 213 VGGHSDLLLGLISANEKWY-PKLRGFMSLLQSVPSNEDCYLGLRGLRTMYIRLKEAEQRG 271
Query: 543 LIIANWLEKHPKIVEVLHP 599
L +A ++E ++++VLHP
Sbjct: 272 LEMARFMESRKEVLKVLHP 290
>UniRef50_A5KK19 Cluster: Putative uncharacterized protein; n=1;
Ruminococcus torques ATCC 27756|Rep: Putative
uncharacterized protein - Ruminococcus torques ATCC
27756
Length = 388
Score = 114 bits (275), Expect = 2e-24
Identities = 56/133 (42%), Positives = 84/133 (63%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
T TL AL +G HIVS +YGG+ LL + LGI +F D ++E V+ A+ E TK
Sbjct: 91 TYTLQALAQNGGHIVSQKTIYGGSYNLLAHTLPNLGITASFVDIHDLEAVERAITEQTKA 150
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
++IET NP + D++A+ ++A + I +VVDNTF TPY +P++ GADIV++S TK+
Sbjct: 151 LYIETLGNPNCDIPDMDALAELAH-KYQIPLVVDNTFGTPYWIRPIEHGADIVVHSATKF 209
Query: 363 MNGHSDVIMGAAI 401
+ GH + G +
Sbjct: 210 IGGHGTTLGGVIV 222
Score = 45.6 bits (103), Expect = 0.001
Identities = 19/56 (33%), Positives = 32/56 (57%)
Frame = +3
Query: 450 MGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLIIANWLEKHPKIVEVLHPXLXTHP 617
MG SP + + + +TL+LR+E H +++ + +L HP + +V HP L HP
Sbjct: 271 MGAAISPFAAFLLLQGTETLSLRLERHAENTKKVIEYLNHHPLVEKVNHPLLADHP 326
>UniRef50_A5ZYG7 Cluster: Putative uncharacterized protein; n=1;
Ruminococcus obeum ATCC 29174|Rep: Putative
uncharacterized protein - Ruminococcus obeum ATCC 29174
Length = 417
Score = 114 bits (274), Expect = 2e-24
Identities = 77/224 (34%), Positives = 117/224 (52%), Gaps = 21/224 (9%)
Frame = +3
Query: 12 LVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWI 191
L+ +L GDH+V++ +YGGT LL ++ G+ TT+ + + + T+ ++
Sbjct: 92 LMNVLQRGDHVVAAAGLYGGTVELLDEL-KVYGVTTTYVKVNTPQAFEAEITPETRAVFA 150
Query: 192 ETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNG 371
ET NP L V DI+ + +IA G I +VDNT TPYL PL GAD+V++S +KY+NG
Sbjct: 151 ETIGNPKLDVTDIQGVAEIAHKYG-IPFLVDNTVATPYLINPLKLGADVVIHSSSKYING 209
Query: 372 HSDVIMGAAIVN-------DKAIGDK----------LRFLQN----AMGIVPSPIDCYFV 488
SD I G I DK G K L L+N +MG +P + +
Sbjct: 210 SSDAISGILISGGKFKWDADKYPGMKEFKKFGPFAYLAKLRNGLFRSMGACLAPQNAFLN 269
Query: 489 NRSLKTLALRMEHHKKSSLIIANWLEKHPKIVEVLHPXLXTHPH 620
N L+TL LRM+ H +++ +A +L + V +P L HP+
Sbjct: 270 NLGLETLGLRMQRHCSNAMELAEFLNGLGHGITVSYPGLKEHPY 313
>UniRef50_A5MZA3 Cluster: O-acetyl-L-homoserine
sulfhydrylase-related protein; n=8; Bacteria|Rep:
O-acetyl-L-homoserine sulfhydrylase-related protein -
Clostridium kluyveri DSM 555
Length = 428
Score = 114 bits (274), Expect = 2e-24
Identities = 60/132 (45%), Positives = 83/132 (62%), Gaps = 2/132 (1%)
Frame = +3
Query: 12 LVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFT--DFTNIEKVKNAMQENTKMI 185
L + N GDHIV+S +YGGT L+ +S++GI TTF D T E++ A Q NTK +
Sbjct: 92 LFNICNCGDHIVASSSIYGGTFNLISVTMSKMGITTTFVSPDCTE-EELNAAFQTNTKAV 150
Query: 186 WIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYM 365
+ ET NP L V+DIE K A + D+ ++VDNTF TP +P ++GADIV +S TKYM
Sbjct: 151 FGETIANPALTVLDIEKFAKAAHAH-DVPLIVDNTFPTPINCRPFEWGADIVTHSTTKYM 209
Query: 366 NGHSDVIMGAAI 401
+GH + G +
Sbjct: 210 DGHGAAVGGVIV 221
>UniRef50_A1I7W3 Cluster: O-acetylhomoserine
aminocarboxypropyltransferase; n=1; Candidatus
Desulfococcus oleovorans Hxd3|Rep: O-acetylhomoserine
aminocarboxypropyltransferase - Candidatus Desulfococcus
oleovorans Hxd3
Length = 419
Score = 114 bits (274), Expect = 2e-24
Identities = 71/226 (31%), Positives = 114/226 (50%), Gaps = 23/226 (10%)
Frame = +3
Query: 9 TLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIW 188
T +ALL GD V+ ++ T +L + + GI + +++ V NA+ + T+ ++
Sbjct: 95 TCMALLRAGDEFVAGTSLFMSTYQLFAGIFKKYGITVRAVNPLDLDAVNNAVTDKTRFVY 154
Query: 189 IETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMN 368
IET NP++ V DI A+ +A G + +VVDNT TP+L +PL+ GAD V++S TKY+
Sbjct: 155 IETIGNPVMDVPDIRALADLAHGHG-LPLVVDNTLGTPFLCRPLELGADAVIHSTTKYLC 213
Query: 369 GHSDVIMGAAIVNDKAIG-DKLRFLQNA----------------------MGIVPSPIDC 479
GH MG +++ A + RF A G +P
Sbjct: 214 GHG-AAMGGVVIDGGAFDWTQERFADFAPFVDRKGRLALLDRIWREHHINFGTTQAPFHS 272
Query: 480 YFVNRSLKTLALRMEHHKKSSLIIANWLEKHPKIVEVLHPXLXTHP 617
Y + TLALRME H +++++A +L P++ V +P L HP
Sbjct: 273 YLTLIGIDTLALRMERHVANAMVVARFLATRPEVAWVNYPGLEDHP 318
>UniRef50_A3SR24 Cluster: Cystathionine gamma-synthase; n=3;
Alphaproteobacteria|Rep: Cystathionine gamma-synthase -
Roseovarius nubinhibens ISM
Length = 386
Score = 113 bits (273), Expect = 3e-24
Identities = 63/205 (30%), Positives = 112/205 (54%), Gaps = 2/205 (0%)
Frame = +3
Query: 9 TLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQEN-TKMI 185
+++ L GDH+V + +Y G + ++ + ++ +++ +++A ++ T+++
Sbjct: 89 SVIDTLKPGDHVVVPEVMYHGVLQQFQRYAKLHRLEVSYYRPGDLDALRDACRKGKTRLV 148
Query: 186 WIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYM 365
W+E+P NP V DI A ++A + G ++ D T P + L+ GAD +S TKY+
Sbjct: 149 WVESPNNPDWDVTDIAAAAELAHAAGAKLLT-DCTGTPPCATRALELGADFSFHSATKYL 207
Query: 366 NGHSDVIMGAAIV-NDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
NGHSDV GA V N A +++ + G V D + + R ++TL LR E ++
Sbjct: 208 NGHSDVTAGALSVRNMDAWWEEIEGHRKLQGTVLQSFDAFLLIRGMRTLTLRYERATLNA 267
Query: 543 LIIANWLEKHPKIVEVLHPXLXTHP 617
L IA E HP++ +VL+P L +HP
Sbjct: 268 LRIATHFEGHPQVRKVLYPGLESHP 292
>UniRef50_Q979X4 Cluster: Cystathionine beta lyase /
O-succinylhomoserine lyase; n=3; Thermoplasma|Rep:
Cystathionine beta lyase / O-succinylhomoserine lyase -
Thermoplasma volcanium
Length = 368
Score = 113 bits (273), Expect = 3e-24
Identities = 62/201 (30%), Positives = 115/201 (57%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
T T++AL GD +V DV+G T + +++ GIN F + + + A++E+ +
Sbjct: 69 TGTILALAKPGDKLVMPTDVFGRTYLFAKNFLTKFGINVKFVE-PGTDSLLGAVEEHADI 127
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
++ E+ +NPLL++ D++ I + A G I +VDNT TP L KP +G DI++ SL+K+
Sbjct: 128 VFFESLSNPLLRLYDVDRICRKASDIG-AITIVDNTLATPILLKPSLYGCDIIIESLSKF 186
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
+ GH++ I G+A + + D + + ++G P+ Y LKT+ LR++ +++
Sbjct: 187 IGGHNNAIGGSA--SGSLMMDTIDENRRSLGSSMDPMSAYLFILGLKTIDLRIKRSSETA 244
Query: 543 LIIANWLEKHPKIVEVLHPXL 605
IA +L ++ + +V +P L
Sbjct: 245 KAIARFLNENNFVSKVYYPGL 265
>UniRef50_Q8EM13 Cluster: O-acetylhomoserine sulfhydrylase; n=86;
cellular organisms|Rep: O-acetylhomoserine sulfhydrylase
- Oceanobacillus iheyensis
Length = 556
Score = 113 bits (272), Expect = 4e-24
Identities = 53/133 (39%), Positives = 82/133 (61%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
T ++ + GD IV+ ++YGGT L + R GIN F D T+ + + +A+ + TK
Sbjct: 93 TLAILNIAGSGDEIVADSNLYGGTFNLFANTLPRYGINVKFVDGTDPQAIDDAITDKTKA 152
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
++ E TNP L V DIE + ++A G + +++DNTF TPY+ KPL +GADIV++S TK+
Sbjct: 153 VFGEIITNPSLYVFDIEKVSEVAHKHG-VPLIIDNTFATPYVTKPLTWGADIVVHSATKW 211
Query: 363 MNGHSDVIMGAAI 401
+ GH I G +
Sbjct: 212 IGGHGTTIGGVVV 224
Score = 44.4 bits (100), Expect = 0.003
Identities = 27/84 (32%), Positives = 48/84 (57%)
Frame = +3
Query: 366 NGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSL 545
NG V +GAA K +++ L++ +G SP + + + + L+TL LR++ H ++L
Sbjct: 247 NGLKYVDLGAAAYITKL---RVQLLRD-IGASLSPQNAFLLLQGLETLHLRIKQHTDNAL 302
Query: 546 IIANWLEKHPKIVEVLHPXLXTHP 617
+A +L+ HP + V +P L HP
Sbjct: 303 QLAKYLQAHPAVEWVNYPGLEEHP 326
>UniRef50_Q0B5H9 Cluster: Cys/Met metabolism
pyridoxal-phosphate-dependent enzymes; n=1; Burkholderia
ambifaria AMMD|Rep: Cys/Met metabolism
pyridoxal-phosphate-dependent enzymes - Burkholderia
cepacia (strain ATCC 53795 / AMMD)
Length = 384
Score = 113 bits (271), Expect = 5e-24
Identities = 60/200 (30%), Positives = 106/200 (53%)
Frame = +3
Query: 6 TTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMI 185
T L L G H++ S Y + V+ R G++ + ++ + E T ++
Sbjct: 93 TVLQTLAAPGGHVLISRSSYPAARKFCDGVLHRQGVSIDEFSLDDPAELAAKLGERTCVV 152
Query: 186 WIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYM 365
+++ P + + + +V+IA G + VVVDNT+ TPY PLD GA + ++S++KY+
Sbjct: 153 YLDLPGSSHFDMCVLREVVEIA---GPVPVVVDNTWATPYFFNPLDHGASVAIHSMSKYI 209
Query: 366 NGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSL 545
GH+D ++GAA+ + ++++ + G D R L+TLA+RM+ H +S+
Sbjct: 210 GGHADSMVGAAVFASLDMYERVKNVSRLAGQAVGADDANLALRGLRTLAVRMDRHFQSAC 269
Query: 546 IIANWLEKHPKIVEVLHPXL 605
+A+WL HP I V +P L
Sbjct: 270 DVASWLRDHPLIESVYYPPL 289
>UniRef50_Q6MN74 Cluster: Cys/Met metabolism lyase; n=1;
Bdellovibrio bacteriovorus|Rep: Cys/Met metabolism lyase
- Bdellovibrio bacteriovorus
Length = 426
Score = 112 bits (270), Expect = 7e-24
Identities = 65/212 (30%), Positives = 118/212 (55%), Gaps = 9/212 (4%)
Frame = +3
Query: 6 TTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENT-KM 182
+TL++LL+ G +++ +YG T LL + RL I+T D + + ++ + + ++
Sbjct: 106 STLMSLLSSGQKVIAHKTLYGCTYSLLTNWLPRLNISTHLMDVNDFKNLELQLADPAARV 165
Query: 183 IWIETPTNPLLKVVDIE---AIVKIA-RSRG---DIIVVVDNTFLTPYLQKPLDFGADIV 341
++ E+ +NP+L++ D++ A+VK A + RG I VVDNTF TP+ +P+++ D V
Sbjct: 166 VYFESVSNPILEIADLQKITALVKAANKKRGKDNQIYTVVDNTFATPWALRPVEWNVDFV 225
Query: 342 MYSLTKYMNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFV-NRSLKTLALR 518
+ SLTK ++G MG A++ + LR + G + P + + + T A+R
Sbjct: 226 IQSLTKNISGFG-TEMGGAVIAPRTHESILRVARKDFGAIIHPYSAWHILVYGISTQAIR 284
Query: 519 MEHHKKSSLIIANWLEKHPKIVEVLHPXLXTH 614
E + S+ +A +LE HPK+ V +P L +H
Sbjct: 285 FEQQQASAWAVAKFLEAHPKVASVTYPGLKSH 316
>UniRef50_Q7WKX4 Cluster: Cys/Met metabolism PLP-dependent enzyme;
n=23; Proteobacteria|Rep: Cys/Met metabolism
PLP-dependent enzyme - Bordetella bronchiseptica
(Alcaligenes bronchisepticus)
Length = 414
Score = 111 bits (267), Expect = 2e-23
Identities = 55/135 (40%), Positives = 87/135 (64%)
Frame = +3
Query: 21 LLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWIETP 200
LL GDH+VSS V+G TN LL ++ LG+ T D T++ +V++A++ NT+M++ ET
Sbjct: 95 LLRRGDHLVSSQYVFGNTNSLLNTLME-LGVEVTMVDATDVRQVRDALRPNTRMVFTETI 153
Query: 201 TNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNGHSD 380
NP +V D+ + + R RG ++ VVDNT +P++ +P++ GA +VM SL+KY+ GH
Sbjct: 154 ANPGTQVADLAGMGALCRERG-LVYVVDNTLTSPWMFRPVEVGASLVMNSLSKYIAGHGH 212
Query: 381 VIMGAAIVNDKAIGD 425
+ GA V D + D
Sbjct: 213 ALGGA--VTDTGLYD 225
Score = 38.3 bits (85), Expect = 0.18
Identities = 16/38 (42%), Positives = 25/38 (65%)
Frame = +3
Query: 501 KTLALRMEHHKKSSLIIANWLEKHPKIVEVLHPXLXTH 614
+TLALRM H ++L +A +L+ HP + V +P L +H
Sbjct: 274 ETLALRMARHCSNALALATFLQGHPGVARVHYPGLSSH 311
>UniRef50_Q65SV6 Cluster: Putative uncharacterized protein; n=1;
Mannheimia succiniciproducens MBEL55E|Rep: Putative
uncharacterized protein - Mannheimia succiniciproducens
(strain MBEL55E)
Length = 332
Score = 111 bits (267), Expect = 2e-23
Identities = 50/133 (37%), Positives = 91/133 (68%), Gaps = 1/133 (0%)
Frame = +3
Query: 12 LVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFT-NIEKVKNAMQENTKMIW 188
L+ L+ GDH +S+ ++YGGT L ++G+ TF + N+++++ A++ NTK ++
Sbjct: 120 LMNLVESGDHFISTTNIYGGTYNLFAHTFRKMGVEVTFVNQDDNLDELRKAIRPNTKAVF 179
Query: 189 IETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMN 368
ET +NP L+V+DIE +A++ + +++DNTF TPY +P +GA+IV++S +KY++
Sbjct: 180 GETISNPTLRVLDIEKFAALAQA-ANAPLIIDNTFATPYFCRPFKYGANIVVHSTSKYLD 238
Query: 369 GHSDVIMGAAIVN 407
GH+ V +G AI++
Sbjct: 239 GHA-VALGGAIID 250
>UniRef50_A6NZI8 Cluster: Putative uncharacterized protein; n=1;
Bacteroides capillosus ATCC 29799|Rep: Putative
uncharacterized protein - Bacteroides capillosus ATCC
29799
Length = 429
Score = 110 bits (264), Expect = 4e-23
Identities = 56/128 (43%), Positives = 82/128 (64%), Gaps = 1/128 (0%)
Frame = +3
Query: 33 GDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIE-KVKNAMQENTKMIWIETPTNP 209
GDH+V+S +YGGT L + R+GI TF D E +++ A + NTK ++ ET NP
Sbjct: 101 GDHVVASSAIYGGTYNLFAVTMKRMGIEFTFVDPECSEAELEAAFKPNTKAVFGETIANP 160
Query: 210 LLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNGHSDVIM 389
L V+DIE K A + G + ++VDNTF TP +P ++GADIV +S TKYM+GH++ +
Sbjct: 161 ALTVLDIEKFAKAAHAHG-VPLIVDNTFPTPVNCRPFEWGADIVTHSTTKYMDGHANAVG 219
Query: 390 GAAIVNDK 413
GA + + K
Sbjct: 220 GAIVDSGK 227
Score = 56.0 bits (129), Expect = 8e-07
Identities = 23/56 (41%), Positives = 37/56 (66%)
Frame = +3
Query: 438 LQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLIIANWLEKHPKIVEVLHPXL 605
L +G +PSP +CY++N L+TL LRM+ H ++L +A +L+ H K+ V +P L
Sbjct: 270 LMRDLGSIPSPQNCYYLNIGLETLPLRMKQHCSNALAVAQYLQSHEKVAWVKYPGL 325
>UniRef50_Q89XR2 Cluster: O-acetylhomoserine sulfhydrylase; n=24;
cellular organisms|Rep: O-acetylhomoserine sulfhydrylase
- Bradyrhizobium japonicum
Length = 433
Score = 109 bits (263), Expect = 5e-23
Identities = 53/129 (41%), Positives = 80/129 (62%)
Frame = +3
Query: 15 VALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWIE 194
V + +HG +IVS +YG T+ LL ++ R GI F + + ++ + ENT+ ++ E
Sbjct: 91 VNVADHGGNIVSVPQLYGTTHTLLSHILPRQGITGRFAESDKPDAIEKLIDENTRAVFAE 150
Query: 195 TPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNGH 374
T NP V DIEA+ KIA + G + ++VDNT TP L KP D+GADI ++SLTK++ GH
Sbjct: 151 TIGNPAGNVCDIEALAKIAHAHG-VPLIVDNTVATPILLKPFDYGADIAVHSLTKFLGGH 209
Query: 375 SDVIMGAAI 401
+ GA +
Sbjct: 210 GTTLGGAIV 218
Score = 40.7 bits (91), Expect = 0.034
Identities = 18/60 (30%), Positives = 34/60 (56%)
Frame = +3
Query: 441 QNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLIIANWLEKHPKIVEVLHPXLXTHPH 620
Q MG V SP + + + + ++T+ALRME H +++ +A +L P++ V + P+
Sbjct: 265 QRTMGSVLSPFNAFLLLQGIETVALRMERHVENARKVAEFLRTDPRVAWVNYTGFPDSPY 324
>UniRef50_Q9SGU9 Cluster: F1N19.23; n=7; Magnoliophyta|Rep: F1N19.23
- Arabidopsis thaliana (Mouse-ear cress)
Length = 441
Score = 109 bits (263), Expect = 5e-23
Identities = 63/216 (29%), Positives = 120/216 (55%), Gaps = 5/216 (2%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRL-GINTTFTDFTNIEKVKNAMQEN-T 176
++ ++ L + G H+V++ +YGGT+ LL + R I T+F D T+ V NA+ E T
Sbjct: 130 SSVMLQLCSSGGHVVAASTLYGGTHALLSHFLPRTCNITTSFVDITDHGAVANAIVEGRT 189
Query: 177 KMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLT 356
++++ E+ NP L V DI + ++A +G + VVVDNTF P + P GAD+V++S++
Sbjct: 190 QVLYFESVANPTLTVADIPELSRMAHEKG-VTVVVDNTF-APMVLSPAKLGADVVVHSIS 247
Query: 357 KYMNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPID---CYFVNRSLKTLALRMEH 527
K+++G +D+I GA ++ + + + ++ ++ ++ + ++ + L LRM
Sbjct: 248 KFISGGADIIAGAVCGSENLVKEMMDLRGGSLMLLGPTMNAKVAFELSERIPHLGLRMRE 307
Query: 528 HKKSSLIIANWLEKHPKIVEVLHPXLXTHPHTXXLK 635
H + + A + ++V++P L THP K
Sbjct: 308 HSHRAQVYAERMRDLG--MKVIYPGLETHPQHKLFK 341
>UniRef50_UPI0000E0F9F5 Cluster: hypothetical protein OM2255_22574;
n=1; alpha proteobacterium HTCC2255|Rep: hypothetical
protein OM2255_22574 - alpha proteobacterium HTCC2255
Length = 411
Score = 109 bits (262), Expect = 6e-23
Identities = 68/227 (29%), Positives = 122/227 (53%), Gaps = 22/227 (9%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
+T +++LL +GDHI+ SD ++G T + + +LGI +F D T+++ V NA Q NT +
Sbjct: 91 STVMLSLLKYGDHIIVSDFLFGNTRSFFKHL-QKLGIEVSFVDVTDVQHVVNAKQPNTVL 149
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
++ E+ +NP+ + D+ AI K + + ++ +VDNT + D GA +V+ SLTKY
Sbjct: 150 VFCESLSNPMTHIADLSAIGKYCQGQ-QLLYIVDNTMSPSVIFSAKDAGASLVISSLTKY 208
Query: 363 MNGHSDVIMGAAI----------VNDK---AIGDKLRF---------LQNAMGIVPSPID 476
++GH V+ G+ + N + +GD ++ L++ +P+P
Sbjct: 209 VSGHGQVLGGSVVDTGLFDWRHYANVEPMYQVGDSAQWGLTQIRKKGLRDMGATLPAP-S 267
Query: 477 CYFVNRSLKTLALRMEHHKKSSLIIANWLEKHPKIVEVLHPXLXTHP 617
+ L+TL LR + +++ +A HPKI +V +P L +HP
Sbjct: 268 ASTILVGLETLDLRYQKACENARKLAQHFMNHPKIKQVFYPGLASHP 314
>UniRef50_Q9YA71 Cluster: Cystathionine gamma-synthase; n=1;
Aeropyrum pernix|Rep: Cystathionine gamma-synthase -
Aeropyrum pernix
Length = 389
Score = 109 bits (261), Expect = 8e-23
Identities = 64/185 (34%), Positives = 98/185 (52%)
Frame = +3
Query: 63 YGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIV 242
YG T LL + S GI + + + +I +E+ NP L+V + I
Sbjct: 108 YGSTRSLLEMLSSITGIEVRLAGPPWEDLLDLVCWAD--LIIVESMANPTLRVPPLSGIY 165
Query: 243 KIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIG 422
+ A S G + VVVDNTF TP +PL+ GA + SLTKY+ GH+DV+ G+ +
Sbjct: 166 REAGSCG-VRVVVDNTFATPIAYRPLERGAHYSLESLTKYIAGHNDVVGGSLSGRVEEDL 224
Query: 423 DKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLIIANWLEKHPKIVEVLHPX 602
+ L ++ +G + PID Y R +KTL R E ++++ +A WLE H K+ +V +P
Sbjct: 225 EPLWNMRKILGTIMQPIDAYLAWRGMKTLKARFEAQSRAAVEVAEWLESHRKVKKVYYPG 284
Query: 603 LXTHP 617
L +HP
Sbjct: 285 LSSHP 289
>UniRef50_A0JYV8 Cluster: Cystathionine gamma-synthase; n=8;
Actinobacteria (class)|Rep: Cystathionine gamma-synthase
- Arthrobacter sp. (strain FB24)
Length = 387
Score = 108 bits (259), Expect = 1e-22
Identities = 63/189 (33%), Positives = 108/189 (57%)
Frame = +3
Query: 39 HIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLK 218
H+V+ +YGG++ +L V LG TFT + V++A++ +T ++ +ETP NP L+
Sbjct: 109 HVVAVRPLYGGSDHILASGV--LGTEVTFT---TADGVRDALRPDTGLVIVETPANPSLE 163
Query: 219 VVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNGHSDVIMGAA 398
+VDI ++AR + ++VDNTF +P LQ+PL GA +V++S TK++ GH D MG
Sbjct: 164 LVDI---AQLARDADGVPLLVDNTFASPVLQQPLAHGATLVLHSATKFLGGHGDA-MGGV 219
Query: 399 IVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLIIANWLEKHPK 578
+ +LR ++ G + +P Y ++R L TL +R+ + ++ +A L H
Sbjct: 220 VAAPVEWTTRLRQVRAVTGGILTPWPAYLLHRGLATLPVRVRAQQATAHKVAAALAGHGL 279
Query: 579 IVEVLHPXL 605
+ V +P L
Sbjct: 280 VKAVHYPGL 288
>UniRef50_Q62BJ4 Cluster: Trans-sulfuration enzyme family protein;
n=15; Burkholderia|Rep: Trans-sulfuration enzyme family
protein - Burkholderia mallei (Pseudomonas mallei)
Length = 433
Score = 107 bits (258), Expect = 2e-22
Identities = 66/209 (31%), Positives = 108/209 (51%), Gaps = 12/209 (5%)
Frame = +3
Query: 15 VALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTD------FTNIEKVKNAMQENT 176
+A L GD +V S +YGGT L+ + G+ D A Q
Sbjct: 116 LAFLRPGDQLVQSVPLYGGTETLIAKYFREWGVGAHSIDNGLSPQAIGAALEAAAQQGPV 175
Query: 177 KMIWIETPTNPLLKVVDIEAIVKI-----ARSRGDIIVVVDNTFLTPYLQKPLDFGADIV 341
++ ++ETP NP ++D++ + + AR I V DNT L P QKP + G D+
Sbjct: 176 RLCYVETPANPTNALIDLDGMRRELDAFEARHGYRPISVCDNTLLGPIFQKPSEHGVDMS 235
Query: 342 MYSLTKYMNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRM 521
+YSLTKY+ GHSD++ G + + + K+R +++A G P + + RS++T+ LRM
Sbjct: 236 VYSLTKYVGGHSDLV-GGGVTGRRDLVAKVRAVRSAFGSQLDPHSSWMLIRSMETVVLRM 294
Query: 522 EHHKKSSLIIANWLEKHP-KIVEVLHPXL 605
+ +++ +A WL +P + V+V HP L
Sbjct: 295 KQAARTASAVAKWLATNPHQKVDVYHPEL 323
>UniRef50_A7CL93 Cluster: Cys/Met metabolism
pyridoxal-phosphate-dependent enzyme; n=1; Ralstonia
pickettii 12D|Rep: Cys/Met metabolism
pyridoxal-phosphate-dependent enzyme - Ralstonia
pickettii 12D
Length = 385
Score = 107 bits (258), Expect = 2e-22
Identities = 59/211 (27%), Positives = 112/211 (53%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
T ++ALL+ GDH++ +D VYG T V+ ++G+ T+ + + +Q NT++
Sbjct: 85 THPMLALLSAGDHVLVADCVYGPTREFCNSVLRKIGVAVTYFA-ADAATIDAHLQSNTRL 143
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
+ +E+P + +++ +I AI + A + G +V++DN + + G DIV +L+KY
Sbjct: 144 VLLESPGSFTMEIQEIAAISREAHTAG-ALVMLDNAWGFGN-SAMFEHGVDIVCTALSKY 201
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
GHSDV +G+ V + + +++ + +G S D + V R L+TL++R+ H +
Sbjct: 202 AAGHSDVCLGSITVRSERLFRQIKTFVSGVGTGVSSDDAFLVLRGLRTLSVRLAEHAQRG 261
Query: 543 LIIANWLEKHPKIVEVLHPXLXTHPHTXXLK 635
L + WL ++ ++HP P K
Sbjct: 262 LDLTQWLRGRREVASLVHPAHPEDPQHQRFK 292
>UniRef50_A4S3Y0 Cluster: Putative 2nd cystathione gamma synthase;
n=1; Ostreococcus lucimarinus CCE9901|Rep: Putative 2nd
cystathione gamma synthase - Ostreococcus lucimarinus
CCE9901
Length = 386
Score = 107 bits (257), Expect = 3e-22
Identities = 55/150 (36%), Positives = 87/150 (58%), Gaps = 6/150 (4%)
Frame = +3
Query: 180 MIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTK 359
++W+E+P NP V+D+E +V +AR+ V VD+T LTP KPL FG D+VM+S TK
Sbjct: 142 LVWVESPANPTWDVMDLEQVVAVARACDAGCVCVDSTVLTPICTKPLSFGVDVVMHSATK 201
Query: 360 YMNGHSDVIMGAAIVND-KAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKK 536
Y+NGH DV+ GA + + ++ + G +D Y ++R ++TL LR+ +
Sbjct: 202 YLNGHGDVVAGALVTRECDDRWQRILHERKLGGATMGSMDAYLLSRGMRTLELRVRRQSE 261
Query: 537 SSLIIANWLEKH-----PKIVEVLHPXLXT 611
S++ IA+ E++ P VL+P L T
Sbjct: 262 SAMWIAHEFEQYLRSRIPHGAIVLYPGLQT 291
>UniRef50_A5MZ94 Cluster: O-acetyl-L-homoserine
sulfhydrylase-related protein; n=4; Bacteria|Rep:
O-acetyl-L-homoserine sulfhydrylase-related protein -
Clostridium kluyveri DSM 555
Length = 442
Score = 107 bits (256), Expect = 3e-22
Identities = 58/148 (39%), Positives = 88/148 (59%), Gaps = 1/148 (0%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTT-FTDFTNIEKVKNAMQENTK 179
T TL+ + G I+++ +YGGT +++ + GI F DF N E + ++ +TK
Sbjct: 92 TYTLLNVAEDGGRILTTPYLYGGTLDGFKKLYPKFGIKIDKFEDFNNPEALAKQIKPDTK 151
Query: 180 MIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTK 359
I++E+ +NP V DIE I K+A DI ++VDNT TPYL P+ +GADIV+YS TK
Sbjct: 152 AIFVESISNPNAAVADIEKIAKVAHEY-DIPLIVDNTLATPYLLNPIKYGADIVIYSATK 210
Query: 360 YMNGHSDVIMGAAIVNDKAIGDKLRFLQ 443
+NGH +VI G + + K + +F Q
Sbjct: 211 ALNGHGNVIAGIILESGKFNWENGKFPQ 238
>UniRef50_A5WGJ5 Cluster: O-acetylhomoserine/O-acetylserine
sulfhydrylase; n=142; Bacteria|Rep:
O-acetylhomoserine/O-acetylserine sulfhydrylase -
Psychrobacter sp. PRwf-1
Length = 437
Score = 106 bits (255), Expect = 5e-22
Identities = 53/133 (39%), Positives = 78/133 (58%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
T + + GD+I+++ +YGGT + R GI F D N + + + E TKM
Sbjct: 101 TYAVQTICEAGDNIIAASTLYGGTYNFFAHTLPRQGIEVRFFDHKNPAAIHDLVDEKTKM 160
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
++ E+ NPL ++DIEAI A G + VV+DNT TP + +P +FGADIV++SLTKY
Sbjct: 161 VFAESIGNPLGNIIDIEAIADAAHKHG-VPVVIDNTVATPAICRPFEFGADIVVHSLTKY 219
Query: 363 MNGHSDVIMGAAI 401
M+G I GA +
Sbjct: 220 MSGTGTSIGGAIV 232
Score = 44.4 bits (100), Expect = 0.003
Identities = 18/55 (32%), Positives = 34/55 (61%)
Frame = +3
Query: 453 GIVPSPIDCYFVNRSLKTLALRMEHHKKSSLIIANWLEKHPKIVEVLHPXLXTHP 617
G SP++ + + + ++TL+LRME H +++ +A +L+ H K+ V + L HP
Sbjct: 283 GAALSPLNAFSILQGIQTLSLRMERHVQNAQAVAEYLKAHDKVAWVKYAGLADHP 337
>UniRef50_Q76K51 Cluster: O-acetyl-L-homoserine sulfhydrylase; n=4;
Thermus|Rep: O-acetyl-L-homoserine sulfhydrylase -
Thermus thermophilus
Length = 412
Score = 104 bits (250), Expect = 2e-21
Identities = 71/230 (30%), Positives = 119/230 (51%), Gaps = 28/230 (12%)
Frame = +3
Query: 12 LVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWI 191
L+ALL GD +V++ ++G T L QV+S +G+ + D E V+ A+ T+ +++
Sbjct: 88 LLALLRPGDEVVAAKGLFGQTIGLFGQVLSLMGVTVRYVD-PEPEAVREALSAKTRAVFV 146
Query: 192 ETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTF-LTPYLQKPLDFGADIVMYSLTKYMN 368
ET NP L V D+EA+ +A G + +VVDNTF L +PL +GA +V+ SLTK+ +
Sbjct: 147 ETVANPALLVPDLEALATLAEEAG-VALVVDNTFGAAGALCRPLAWGAHVVVESLTKWAS 205
Query: 369 GHSDVIMGAAIVNDKAIGDKL-RFLQ--------------------------NAMGIVPS 467
GH V+ GA + + + +FLQ + G+ S
Sbjct: 206 GHGSVLGGAVLSRETELWRNYPQFLQPDLKGQIPWEALRARCFPERVRTLGLSLCGMALS 265
Query: 468 PIDCYFVNRSLKTLALRMEHHKKSSLIIANWLEKHPKIVEVLHPXLXTHP 617
P + Y + + L+T+ALR+ +++ +A L+ HPK+ + +P L P
Sbjct: 266 PFNAYLLFQGLETVALRVARMSETARFLAERLQGHPKVKALRYPGLPEDP 315
>UniRef50_A6GJL1 Cluster: Methionine gamma-lyase; n=1; Plesiocystis
pacifica SIR-1|Rep: Methionine gamma-lyase -
Plesiocystis pacifica SIR-1
Length = 399
Score = 104 bits (250), Expect = 2e-21
Identities = 66/204 (32%), Positives = 99/204 (48%), Gaps = 5/204 (2%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAM-----Q 167
TTTL L+ G + ++ VYGGT +LR + G+ D E + + Q
Sbjct: 94 TTTLTTLVPAGGRVACAEVVYGGTESVLRHELEPRGVRCDRFDARRPETLAPLLDPPPGQ 153
Query: 168 ENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMY 347
++W E+ NPL+++ I AI ++ G + + VD TF Q PL GA +V++
Sbjct: 154 AKPDLVWCESIANPLMRIGQISAIARLCADAG-VPLGVDATFAGGMAQNPLALGASVVVH 212
Query: 348 SLTKYMNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEH 527
S TK +NGHSDV+ G AI +D A D G P + + R ++TL LR
Sbjct: 213 SATKVLNGHSDVVAG-AIASDAARVDACFATIKRQGGCVDPQAAWLLQRGIRTLPLRWAA 271
Query: 528 HKKSSLIIANWLEKHPKIVEVLHP 599
++S +A L HPK+ V P
Sbjct: 272 QTRNSEFLAERLRDHPKVRAVHWP 295
>UniRef50_A2Z703 Cluster: Putative uncharacterized protein; n=3;
Oryza sativa|Rep: Putative uncharacterized protein -
Oryza sativa subsp. indica (Rice)
Length = 451
Score = 104 bits (250), Expect = 2e-21
Identities = 55/156 (35%), Positives = 93/156 (59%), Gaps = 2/156 (1%)
Frame = +3
Query: 9 TLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTN-IEKVKNAMQEN-TKM 182
TL+AL+ G H+V + D Y + +S++GI +TF D + +E +++ + E+ M
Sbjct: 171 TLLALVPPGGHVVVTADCYSEARAFIHDKLSKMGITSTFVDLDDDMEALESVLDEDEVTM 230
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
+ ++ TNP LKVVD+ + ++ RG +V +D+T +P QKPL GAD+V++S TKY
Sbjct: 231 FYADSMTNPHLKVVDVARVAELCHRRG-ALVCIDSTLASPINQKPLALGADVVLHSATKY 289
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSP 470
+ GH DVI G + +A+ ++R + +G SP
Sbjct: 290 IAGHHDVIAG-CVSGSEALISRIRAWHHDLGGAISP 324
>UniRef50_Q7VIG9 Cluster: O-acetylhomoserine (Thiol)-lyase MetY;
n=18; Epsilonproteobacteria|Rep: O-acetylhomoserine
(Thiol)-lyase MetY - Helicobacter hepaticus
Length = 430
Score = 104 bits (249), Expect = 2e-21
Identities = 53/131 (40%), Positives = 76/131 (58%), Gaps = 1/131 (0%)
Frame = +3
Query: 12 LVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEK-VKNAMQENTKMIW 188
+V GD+IV S+ +YGGT L + R GI T D NIE +++ + + TK I+
Sbjct: 97 IVNCAQSGDNIVFSNKIYGGTQTLFVHTLKRFGIQTKVFDIDNIESSLESVIDDKTKAIF 156
Query: 189 IETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMN 368
E+ +NP + + D E I IA+ II + DNT T +L KP D+G DI +YSL+KY+N
Sbjct: 157 FESISNPQISIADTEKITAIAKKH-KIISICDNTIPTAFLHKPFDYGVDISIYSLSKYIN 215
Query: 369 GHSDVIMGAAI 401
G + GA I
Sbjct: 216 GQGSALGGAII 226
>UniRef50_Q0SFV6 Cluster: O-acetylhomoserine
aminocarboxypropyltransferase; n=1; Rhodococcus sp.
RHA1|Rep: O-acetylhomoserine
aminocarboxypropyltransferase - Rhodococcus sp. (strain
RHA1)
Length = 432
Score = 104 bits (249), Expect = 2e-21
Identities = 50/130 (38%), Positives = 75/130 (57%)
Frame = +3
Query: 12 LVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWI 191
L+ L G HIV++ +YGGT LL + GI T D +++ + A + T+ +
Sbjct: 94 LLTLAKSGQHIVAARQLYGGTVDLLSDTFADFGIEVTLVDQDDLDAWRAAARPETRAFFA 153
Query: 192 ETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNG 371
ET NP+ V+D+ A+ IA G + ++VDNT TPYL +P DFGADI +YS TK++ G
Sbjct: 154 ETIGNPVASVLDVRAVADIAHQAG-VPLIVDNTIATPYLLRPKDFGADITVYSATKFIGG 212
Query: 372 HSDVIMGAAI 401
H + G +
Sbjct: 213 HGSSLGGVIV 222
Score = 39.5 bits (88), Expect = 0.078
Identities = 19/52 (36%), Positives = 32/52 (61%)
Frame = +3
Query: 450 MGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLIIANWLEKHPKIVEVLHPXL 605
+G SP + + + + L+TL LR+E S+L IA +L+ HP + +V +P L
Sbjct: 274 LGPALSPFNSFQLLQGLETLDLRLERQVGSALAIARFLDGHPAVAKVNYPGL 325
>UniRef50_Q7M9C8 Cluster: O-ACETYLHOMOSERINE SULFHYDRYLASE; n=1;
Wolinella succinogenes|Rep: O-ACETYLHOMOSERINE
SULFHYDRYLASE - Wolinella succinogenes
Length = 407
Score = 103 bits (248), Expect = 3e-21
Identities = 69/225 (30%), Positives = 116/225 (51%), Gaps = 20/225 (8%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
+T ++ L GD +V++D ++G T L ++ + GI F D + V++A E TK+
Sbjct: 88 STAILTLARAGDSVVTTDRLFGHTLSLFQKTLPSFGIEVRFVDVMDSLAVEHACDETTKL 147
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
+++ET +NP L+V D+EA+ K+ ++G I +VVD T PYL + G DI + S TK+
Sbjct: 148 LFLETISNPQLQVADLEALSKVVHAKG-IPLVVDTTMTPPYLLEAKRLGVDIEVLSSTKF 206
Query: 363 MNGHSDVIMGAAIVND-------------KAIGDKLRFLQNA-------MGIVPSPIDCY 482
++G + G I + A + FL A +G SP + Y
Sbjct: 207 ISGGGTSVGGVLIDHGLFEWKSLPSLAPYYAKAGPMAFLYKARKEVFQNLGPSLSPHNAY 266
Query: 483 FVNRSLKTLALRMEHHKKSSLIIANWLEKHPKIVEVLHPXLXTHP 617
+ L+T+ALR+E +++ +A+WL P++ V HP L P
Sbjct: 267 LQSLGLETMALRIERSCQNAQELAHWLLSIPQVKCVNHPSLPDSP 311
>UniRef50_A3K0Q5 Cluster: O-succinylhomoserine sulfhydrylase; n=3;
Rhodobacteraceae|Rep: O-succinylhomoserine sulfhydrylase
- Sagittula stellata E-37
Length = 391
Score = 103 bits (248), Expect = 3e-21
Identities = 56/202 (27%), Positives = 108/202 (53%)
Frame = +3
Query: 12 LVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWI 191
L+AL GDH+V+S ++G +L V++R G+ T D T+ + A++++T+++++
Sbjct: 92 LMALTKAGDHVVASRALFGSCLYVLEDVLARFGVEVTLIDGTDNAAWEAAVRDDTRLVFL 151
Query: 192 ETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNG 371
E+ +NP L+V+D+ + K+A ++G +V+ D+ TP GADI + S TK+++G
Sbjct: 152 ESISNPTLEVIDLAHVCKVAHAKG-ALVLCDDAMATPVYSYARACGADISIVSTTKHVDG 210
Query: 372 HSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLII 551
++ G + I + G +P + ++L+TL LR+ + ++ +
Sbjct: 211 QGRMLGGMICGPKELIRGPIEAYMKHSGGAMNPFTAWTHLKALETLELRVRAQAQGAMAL 270
Query: 552 ANWLEKHPKIVEVLHPXLXTHP 617
A L H K+ V +P HP
Sbjct: 271 AEALNGHEKLNHVRYPTHAAHP 292
>UniRef50_A1W861 Cluster: Cys/Met metabolism
pyridoxal-phosphate-dependent enzymes; n=10; cellular
organisms|Rep: Cys/Met metabolism
pyridoxal-phosphate-dependent enzymes - Acidovorax sp.
(strain JS42)
Length = 415
Score = 103 bits (246), Expect = 6e-21
Identities = 60/216 (27%), Positives = 106/216 (49%), Gaps = 11/216 (5%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
+T +ALL GD ++ D+ YG L + GI D + + + + + T++
Sbjct: 93 STVSLALLRQGDEVLIPDNAYGPNKALAEVELRHYGIRHRIYDPLDPADLASKITDATRL 152
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDF-----------G 329
+W+E P + L+ D+ V+I R+RG + V+DNT+ P D G
Sbjct: 153 VWLEAPGSVTLEFPDLVEQVRICRARG-VATVLDNTWGAGLAFAPFDLLGRGARAEGALG 211
Query: 330 ADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTL 509
D+ +++LTKY +G DV+MG+ D+ + +++ +G+ D V R+L ++
Sbjct: 212 VDVSVHALTKYPSGGGDVLMGSITTRDEGLHLRIKLTHMRLGLGVGANDVEAVLRALPSM 271
Query: 510 ALRMEHHKKSSLIIANWLEKHPKIVEVLHPXLXTHP 617
ALR H ++ +A W+ P + +VLHP L P
Sbjct: 272 ALRYHAHDAAARDLAQWMGLQPAVAQVLHPALPGSP 307
>UniRef50_Q67KY0 Cluster: O-acetylhomoserine sulfhydrylase; n=28;
cellular organisms|Rep: O-acetylhomoserine sulfhydrylase
- Symbiobacterium thermophilum
Length = 435
Score = 102 bits (245), Expect = 7e-21
Identities = 52/133 (39%), Positives = 79/133 (59%)
Frame = +3
Query: 9 TLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIW 188
T++A+ N GD IV+S +YGGT L + + GI F D ++ A+ T++I+
Sbjct: 100 TVLAICNAGDEIVTSSSLYGGTYNLFATTLPKWGITARFVDAHDLAGFHRAITPRTRLIF 159
Query: 189 IETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMN 368
E NP L V DI + IA G + +V+DNTF TP L +P++ GAD+V++S TK++
Sbjct: 160 GEVIGNPRLDVFDIAGVAAIAHEHG-LPLVIDNTFATPMLCRPIEHGADLVIHSATKWLG 218
Query: 369 GHSDVIMGAAIVN 407
GH V MG +V+
Sbjct: 219 GHG-VAMGGVVVD 230
Score = 44.4 bits (100), Expect = 0.003
Identities = 21/56 (37%), Positives = 33/56 (58%)
Frame = +3
Query: 450 MGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLIIANWLEKHPKIVEVLHPXLXTHP 617
+G SP + + + L TLALRM +++L IA +L +HP + V +P L +HP
Sbjct: 277 LGGCQSPFNAFLLLLGLDTLALRMRAISENALEIARYLSEHPAVAWVRYPGLPSHP 332
>UniRef50_UPI0000E4882F Cluster: PREDICTED: hypothetical protein,
partial; n=2; Strongylocentrotus purpuratus|Rep:
PREDICTED: hypothetical protein, partial -
Strongylocentrotus purpuratus
Length = 806
Score = 102 bits (244), Expect = 1e-20
Identities = 47/81 (58%), Positives = 55/81 (67%)
Frame = +3
Query: 309 QKPLDFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFV 488
++ LDFGADIVMYS TKYMNGHSDV+MG ND + KL F A G PSP DC+ V
Sbjct: 726 RRGLDFGADIVMYSATKYMNGHSDVVMGLVACNDDELHKKLHFQLYAAGSCPSPFDCFLV 785
Query: 489 NRSLKTLALRMEHHKKSSLII 551
NR LKTL +RM H KS + +
Sbjct: 786 NRGLKTLHVRMRQHYKSGIAV 806
>UniRef50_Q1DAY0 Cluster: Cys/Met metabolism PLP-dependent enzyme;
n=2; Cystobacterineae|Rep: Cys/Met metabolism
PLP-dependent enzyme - Myxococcus xanthus (strain DK
1622)
Length = 394
Score = 102 bits (244), Expect = 1e-20
Identities = 60/195 (30%), Positives = 100/195 (51%)
Frame = +3
Query: 33 GDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPL 212
GD +V D YG T L + + + LG+ T+ E + +M+ E+ +NPL
Sbjct: 99 GDKLVMPADGYGVTRALYKSLCATLGVELHAFLMTDPEVPERIRALKPRMVLAESISNPL 158
Query: 213 LKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNGHSDVIMG 392
L+V D+ + + + G VV D TF +P Q+ L GAD + S +K++NGHSD + G
Sbjct: 159 LRVPDLRVLARACQDVGATFVV-DGTFPSPVGQRALALGADYAVQSTSKWLNGHSDALGG 217
Query: 393 AAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLIIANWLEKH 572
+ + + LR + G V P + + R L+TL +RM+ H + + +A L +
Sbjct: 218 TVSASRERMA-PLRAARVLAGDVLGPFEAWLTLRGLRTLPVRMKAHVEHAAHVARRLMES 276
Query: 573 PKIVEVLHPXLXTHP 617
P + V++P L +HP
Sbjct: 277 PLLERVIYPGLTSHP 291
>UniRef50_A2Y9X5 Cluster: Putative uncharacterized protein; n=1;
Oryza sativa (indica cultivar-group)|Rep: Putative
uncharacterized protein - Oryza sativa subsp. indica
(Rice)
Length = 408
Score = 99.1 bits (236), Expect(2) = 1e-20
Identities = 49/111 (44%), Positives = 74/111 (66%), Gaps = 1/111 (0%)
Frame = +3
Query: 129 DFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYL 308
D T I +V +A+ TK++W+E+PTNP L++ DI+ I +IA G +V+VDN+ ++P L
Sbjct: 177 DTTKISEVTSAIGPLTKLVWLESPTNPRLQITDIKKIAEIAHYHG-ALVLVDNSIMSPVL 235
Query: 309 QKPLDFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGDKLRFLQ-NAMGI 458
+PL+ GADIVM+S TK++ GHSD++ G V + G L + Q NA I
Sbjct: 236 SRPLELGADIVMHSATKFIAGHSDLMAGILAVKGERDGPPLYYWQANAQKI 286
Score = 23.8 bits (49), Expect(2) = 1e-20
Identities = 9/23 (39%), Positives = 14/23 (60%)
Frame = +3
Query: 549 IANWLEKHPKIVEVLHPXLXTHP 617
IA +L HP++ +V + L HP
Sbjct: 286 IAEFLASHPRVKKVNYAGLPDHP 308
>UniRef50_Q5LN68 Cluster: Cys/Met metabolism PLP-dependent enzyme
family protein; n=2; Rhodobacterales|Rep: Cys/Met
metabolism PLP-dependent enzyme family protein -
Silicibacter pomeroyi
Length = 371
Score = 101 bits (241), Expect = 2e-20
Identities = 59/205 (28%), Positives = 102/205 (49%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
+ L A L G ++ D Y T L + + LG+N + +
Sbjct: 84 SAALFATLQAGQRLLIPADGYYVTRLLADRYLRPLGVNVEERPTAGFAEGGFG---GFDV 140
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
+++ETP+NP L ++D+ A+ + R+ G I + DNT +TP Q+PLD G DIV+ S TK
Sbjct: 141 VFLETPSNPGLDLIDLAAVARAVRAAGGI-TICDNTTMTPLGQRPLDLGIDIVVASDTKA 199
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
M GHSD+++G D + + + G +P P + + ++R L+TL +R + +++
Sbjct: 200 MGGHSDLLLGHVASRDAGLVQAIEDWRRISGAIPGPHEAWLLHRGLETLEVRFDRMCRNA 259
Query: 543 LIIANWLEKHPKIVEVLHPXLXTHP 617
+A L +H + + P L P
Sbjct: 260 EALAPRLARHRAVSALRFPGLPGDP 284
>UniRef50_Q895W3 Cluster: O-acetylhomoserine sulfhydrylase; n=40;
Bacteria|Rep: O-acetylhomoserine sulfhydrylase -
Clostridium tetani
Length = 462
Score = 99 bits (238), Expect = 5e-20
Identities = 53/137 (38%), Positives = 84/137 (61%), Gaps = 4/137 (2%)
Frame = +3
Query: 3 TTTLVALLN---HGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTD-FTNIEKVKNAMQE 170
+ T +ALLN GDHI+S+ +YGGT LL + + GI +F + ++ E + +
Sbjct: 124 SATTLALLNICKSGDHIISASTIYGGTFTLLSSTLKKFGIEVSFINPDSSKEDILKEFKS 183
Query: 171 NTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYS 350
NTK I+ ET NP L ++D + IA+ + ++ +VDNT +PYL PL+ GA+IV++S
Sbjct: 184 NTKAIFAETIGNPGLNILDFDKFSDIAQ-KTEVPFIVDNTLASPYLCSPLELGANIVIHS 242
Query: 351 LTKYMNGHSDVIMGAAI 401
TKY++GH+ I G +
Sbjct: 243 STKYIDGHATSIGGIIV 259
Score = 42.7 bits (96), Expect = 0.008
Identities = 21/52 (40%), Positives = 31/52 (59%)
Frame = +3
Query: 450 MGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLIIANWLEKHPKIVEVLHPXL 605
+G SP + + N L+TL LRME H ++L +A +LE H K+ V +P L
Sbjct: 307 LGTCLSPFNAFLNNLGLETLHLRMERHCSNTLKLAKFLENHKKVNWVNYPGL 358
>UniRef50_A1TP30 Cluster: Cys/Met metabolism
pyridoxal-phosphate-dependent enzyme; n=1; Acidovorax
avenae subsp. citrulli AAC00-1|Rep: Cys/Met metabolism
pyridoxal-phosphate-dependent enzyme - Acidovorax avenae
subsp. citrulli (strain AAC00-1)
Length = 396
Score = 99.5 bits (237), Expect = 7e-20
Identities = 57/195 (29%), Positives = 101/195 (51%)
Frame = +3
Query: 15 VALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWIE 194
+ALL+ GD + + YG ++LR V R GI D + A+ +T+++ +E
Sbjct: 95 MALLSPGDVVAMPTNGYGTAQQMLRNVFHRFGIGIVLYDPMAPDTWAEAVPPSTRLLCVE 154
Query: 195 TPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNGH 374
P + ++V D+ + +A RG I +DNT+ + + G + + +LTK +G
Sbjct: 155 APGSVTMEVPDLRRLAGLAGERG-CIAAIDNTYSAGLHLRAFELGFHVSVQALTKLQSGG 213
Query: 375 SDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLIIA 554
+D++MG+ + I L ++ +G+ SP D Y V R L TL+LR + ++SL +A
Sbjct: 214 ADLVMGSVGSVREDISRSLCETRHFLGMHVSPDDIYLVLRGLPTLSLRYAANTEASLRLA 273
Query: 555 NWLEKHPKIVEVLHP 599
W + +I V+HP
Sbjct: 274 EWFSEKKEIAAVMHP 288
>UniRef50_Q31RB7 Cluster: O-acetylhomoserine/O-acetylserine
sulfhydrylase; n=3; cellular organisms|Rep:
O-acetylhomoserine/O-acetylserine sulfhydrylase -
Synechococcus sp. (strain PCC 7942) (Anacystis nidulans
R2)
Length = 434
Score = 99.1 bits (236), Expect = 9e-20
Identities = 52/130 (40%), Positives = 74/130 (56%)
Frame = +3
Query: 12 LVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWI 191
+ A+ + G +I+S+ ++YGGT L R + R GI F D ++ V A+ ENT++++
Sbjct: 92 IAAITSAGQNIISTTNLYGGTINLFRHTLKRFGIEVRFVDSSDASSVAAAIDENTRLVYT 151
Query: 192 ETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNG 371
E+ NP V D EAI IA G I +VDNT P L PL+ GAD+V+ SLTK G
Sbjct: 152 ESIGNPKGNVDDFEAIAAIAHDSG-IPFIVDNTVSPPPLFNPLEHGADVVVLSLTKLAGG 210
Query: 372 HSDVIMGAAI 401
H + G I
Sbjct: 211 HGTSLGGIVI 220
Score = 48.4 bits (110), Expect = 2e-04
Identities = 21/56 (37%), Positives = 33/56 (58%)
Frame = +3
Query: 450 MGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLIIANWLEKHPKIVEVLHPXLXTHP 617
+G SP + V ++TL LR E H +++ +A WLE+HP + V +P L +HP
Sbjct: 276 IGATLSPFNAQQVLLGVETLPLRAERHVRNAQAVAEWLERHPLVTWVNYPGLPSHP 331
>UniRef50_O42851 Cluster: Uncharacterized trans-sulfuration enzyme
C23A1.14c; n=1; Schizosaccharomyces pombe|Rep:
Uncharacterized trans-sulfuration enzyme C23A1.14c -
Schizosaccharomyces pombe (Fission yeast)
Length = 398
Score = 99.1 bits (236), Expect = 9e-20
Identities = 58/169 (34%), Positives = 95/169 (56%)
Frame = +3
Query: 63 YGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIV 242
Y GT +++ ++ G+ T+F I+ +A+ E +IW+ETP NPL DI
Sbjct: 121 YSGTIQIIARINRLTGLETSF-----IDGKCDAIGEGD-VIWLETPLNPLGIAFDIPFYK 174
Query: 243 KIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIG 422
++A+ +G I+VV D+TF P +Q L GAD V++S TKY+ GHSDV+ G D++
Sbjct: 175 ELAKKKGAILVV-DSTFAPPPIQDALVLGADYVVHSATKYLAGHSDVLAGVTASKDRSKI 233
Query: 423 DKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLIIANWLEK 569
L+ + +G + P + + RSL+T LR+ H ++ ++A L K
Sbjct: 234 LDLKADRAYLGTILHPQQAFLLLRSLRTFPLRIAKHSENGFLVAQHLNK 282
>UniRef50_A3PXR9 Cluster: Cys/Met metabolism
pyridoxal-phosphate-dependent enzymes; n=7;
Actinomycetales|Rep: Cys/Met metabolism
pyridoxal-phosphate-dependent enzymes - Mycobacterium
sp. (strain JLS)
Length = 367
Score = 98.3 bits (234), Expect = 2e-19
Identities = 64/205 (31%), Positives = 101/205 (49%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
T+ L L G+ +V D Y R + ++ G+ T + E + A + +
Sbjct: 83 TSALRVLTGPGERLVVPADGYYQVRRYAAEYLAPQGV--TVLEVATAEMCEAAADAD--V 138
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
+ ETP NP L+VVD+ + R RG ++V DNT TP Q+PL GA++V+ S TK
Sbjct: 139 VLAETPANPGLEVVDLHRLAMTCRRRGATLIV-DNTTATPLGQQPLSLGANLVVASATKA 197
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
++GHSD+I G + + L + G + P + + V RSL + LR E +++
Sbjct: 198 LSGHSDLIAGYVAGSHPEMMAALETDRLLAGPILGPFEAWLVLRSLGSAGLRFERQCQNA 257
Query: 543 LIIANWLEKHPKIVEVLHPXLXTHP 617
L +A L HP + V +P L P
Sbjct: 258 LAVAMLLRNHPAVRGVRYPGLPEDP 282
>UniRef50_Q1NS60 Cluster: O-acetylhomoserine
aminocarboxypropyltransferase; n=3; Bacteria|Rep:
O-acetylhomoserine aminocarboxypropyltransferase - delta
proteobacterium MLMS-1
Length = 415
Score = 97.9 bits (233), Expect = 2e-19
Identities = 68/225 (30%), Positives = 115/225 (51%), Gaps = 20/225 (8%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
TTT++AL G +IV+ ++G T LL + + G+ T F + + V A+ NT
Sbjct: 91 TTTILALAGAGSNIVAGRSLFGNTVSLLARTLKPWGLETRFVEMKDQAAVAAAIDHNTAA 150
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
I++E+ TNP L+V D+ A+ + A++RG + ++VDNT T YL + + GA + + S TKY
Sbjct: 151 IFLESITNPRLEVCDLPALAEFAQARG-VPLLVDNTATTFYLCRVGELGAAVEIISSTKY 209
Query: 363 MNGHSDVIMGAAIVN-------DKAIGDKL-------------RFLQNAMGIVPSPIDCY 482
++G + G I + +G+ R + +G +P + Y
Sbjct: 210 ISGGGAAVGGLIIDHGSFDWHRSPRMGEYARQFGPFALLAALRREIARDLGACLAPHNAY 269
Query: 483 FVNRSLKTLALRMEHHKKSSLIIANWLEKHPKIVEVLHPXLXTHP 617
L+TLALR+E ++L +A +L P + +V +P L HP
Sbjct: 270 LQTLGLETLALRVEQSCANALELARFLAGQPAVRKVNYPGLEEHP 314
>UniRef50_P06106 Cluster: Protein MET17 [Includes:
O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) (OAH
sulfhydrylase) (Homocysteine synthase); O- acetylserine
sulfhydrylase (EC 2.5.1.47) (OAS sulfhydrylase)]; n=107;
cellular organisms|Rep: Protein MET17 [Includes:
O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) (OAH
sulfhydrylase) (Homocysteine synthase); O- acetylserine
sulfhydrylase (EC 2.5.1.47) (OAS sulfhydrylase)] -
Saccharomyces cerevisiae (Baker's yeast)
Length = 444
Score = 97.1 bits (231), Expect = 4e-19
Identities = 55/138 (39%), Positives = 75/138 (54%), Gaps = 1/138 (0%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
T + L + GD+IVS+ +YGGT + R GI F + N E+ + E TK
Sbjct: 91 TLAIQGLAHTGDNIVSTSYLYGGTYNQFKISFKRFGIEARFVEGDNPEEFEKVFDERTKA 150
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTF-LTPYLQKPLDFGADIVMYSLTK 359
+++ET NP V D E IV IA G I VVVDNTF Y +P+ +GADIV +S TK
Sbjct: 151 VYLETIGNPKYNVPDFEKIVAIAHKHG-IPVVVDNTFGAGGYFCQPIKYGADIVTHSATK 209
Query: 360 YMNGHSDVIMGAAIVNDK 413
++ GH I G + + K
Sbjct: 210 WIGGHGTTIGGIIVDSGK 227
Score = 46.0 bits (104), Expect = 9e-04
Identities = 19/57 (33%), Positives = 36/57 (63%)
Frame = +3
Query: 450 MGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLIIANWLEKHPKIVEVLHPXLXTHPH 620
+G + +P + + + ++TL+LR E H +++L +A WLE+ P + V +P L +H H
Sbjct: 273 LGPLMNPFASFLLLQGVETLSLRAERHGENALKLAKWLEQSPYVSWVSYPGLASHSH 329
>UniRef50_A5CMC2 Cluster: O-acetylhomoserine (Thiol)-lyase; n=2;
Actinomycetales|Rep: O-acetylhomoserine (Thiol)-lyase -
Clavibacter michiganensis subsp. michiganensis (strain
NCPPB 382)
Length = 453
Score = 96.7 bits (230), Expect = 5e-19
Identities = 48/134 (35%), Positives = 79/134 (58%), Gaps = 1/134 (0%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTD-FTNIEKVKNAMQENTK 179
TT L+A+L GD I+SS +Y G L RQ + RLGI F D ++++ + T+
Sbjct: 111 TTALLAILQAGDRILSSSSIYEGNRGLFRQNLGRLGIGVDFVDDHRDLDEWARRITPETR 170
Query: 180 MIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTK 359
+++ E NP ++D+ I +A G + VVD+T TPYL +P++ GAD+V++S +K
Sbjct: 171 VLFGEPIPNPKNDLLDLAGIADVAHRHG-LPFVVDDTLATPYLLRPIEHGADVVVHSTSK 229
Query: 360 YMNGHSDVIMGAAI 401
++ GH V+ G +
Sbjct: 230 FLAGHGSVLGGVVV 243
Score = 43.2 bits (97), Expect = 0.006
Identities = 17/55 (30%), Positives = 33/55 (60%)
Frame = +3
Query: 453 GIVPSPIDCYFVNRSLKTLALRMEHHKKSSLIIANWLEKHPKIVEVLHPXLXTHP 617
G P+P + + + ++TL+LR+E H ++L +A +LE P++ V + L + P
Sbjct: 294 GPTPAPFSSFLLRQGIETLSLRVERHSANALAVARFLEARPEVSSVDYAGLESSP 348
>UniRef50_Q6F7Q9 Cluster: Putative cystathionine beta-lyase,
PLP-dependent; n=1; Acinetobacter sp. ADP1|Rep: Putative
cystathionine beta-lyase, PLP-dependent - Acinetobacter
sp. (strain ADP1)
Length = 397
Score = 95.1 bits (226), Expect = 1e-18
Identities = 55/203 (27%), Positives = 100/203 (49%), Gaps = 5/203 (2%)
Frame = +3
Query: 24 LNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWIETPT 203
L+HGD + D++YG L + R GI + I+ E T+++W+E
Sbjct: 98 LSHGDEVWVPDNIYGPNMEHLNNLRQRYGIQVRI--YNPIDAESFIPSEKTRLLWLEAAG 155
Query: 204 NPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFG-----ADIVMYSLTKYMN 368
+ ++ D+ +V+ A++ ++ +DNT+ DF DI +++LTKY +
Sbjct: 156 SITMEFPDLIQLVRKAQA-AQVLTALDNTWGAGLAFNAFDFSNEHLSVDITVHALTKYPS 214
Query: 369 GHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLI 548
G D++MG+ I DK + +L + GI S D + RSL + LR + +++
Sbjct: 215 GGGDILMGSVITRDKNLYQQLFKIHANQGICVSGDDTAQIIRSLAHMRLRYQQQAENAQK 274
Query: 549 IANWLEKHPKIVEVLHPXLXTHP 617
+ WL++ P+ ++VLHP P
Sbjct: 275 LLEWLQQQPQCIQVLHPAASNSP 297
>UniRef50_Q5UZ20 Cluster: O-acetylhomoserine (Thiol)-lyase; n=10;
cellular organisms|Rep: O-acetylhomoserine (Thiol)-lyase
- Haloarcula marismortui (Halobacterium marismortui)
Length = 432
Score = 95.1 bits (226), Expect = 1e-18
Identities = 47/127 (37%), Positives = 69/127 (54%)
Frame = +3
Query: 21 LLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWIETP 200
L + GD++V++ +YGGT R G+ T F D + + A+ ENT + ET
Sbjct: 100 LADVGDNVVTASSLYGGTYTYYTHTAPRNGVETRFVDTLDYDAYAEAIDENTAYVHCETI 159
Query: 201 TNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNGHSD 380
NP L D E + +IA G + VDNTF TPYL P++ GAD+V S TK+++GH
Sbjct: 160 GNPSLVTPDFERLAEIAHDHG-VPFFVDNTFATPYLCNPIEHGADLVWNSTTKWIHGHGT 218
Query: 381 VIMGAAI 401
+ G +
Sbjct: 219 TVGGVLV 225
Score = 41.1 bits (92), Expect = 0.025
Identities = 18/55 (32%), Positives = 31/55 (56%)
Frame = +3
Query: 450 MGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLIIANWLEKHPKIVEVLHPXLXTH 614
+G SP D + + L+TL RM+ H +++ +A +L HP++ V +P L H
Sbjct: 275 LGCQQSPFDAWQTMQGLETLPARMDRHCDNAMGVAEFLADHPEVSWVTYPGLEDH 329
>UniRef50_A0V4A3 Cluster: O-acetylhomoserine/O-acetylserine
sulfhydrylase; n=3; Proteobacteria|Rep:
O-acetylhomoserine/O-acetylserine sulfhydrylase -
Delftia acidovorans SPH-1
Length = 475
Score = 94.7 bits (225), Expect = 2e-18
Identities = 43/130 (33%), Positives = 78/130 (60%)
Frame = +3
Query: 12 LVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWI 191
L L + GDH+V + +YGGT+ + V++ G+ +T + + ++ A+ TK +++
Sbjct: 109 LATLASAGDHVVVASQLYGGTHNFIAHVLASRGVQSTAVAKDDFQALRRAIGPRTKAVFV 168
Query: 192 ETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNG 371
E+ NP + D+ + I+ + G + +VVDNT +P L +P D+GADIV++S TK + G
Sbjct: 169 ESVGNPSGGIADLRQLADISHAAG-VALVVDNTVASPLLLRPFDWGADIVVHSATKAIGG 227
Query: 372 HSDVIMGAAI 401
H +V+ G +
Sbjct: 228 HGNVLGGLIV 237
>UniRef50_A1SMU4 Cluster: O-acetylhomoserine/O-acetylserine
sulfhydrylase; n=6; Bacteria|Rep:
O-acetylhomoserine/O-acetylserine sulfhydrylase -
Nocardioides sp. (strain BAA-499 / JS614)
Length = 428
Score = 94.3 bits (224), Expect = 3e-18
Identities = 51/140 (36%), Positives = 79/140 (56%), Gaps = 3/140 (2%)
Frame = +3
Query: 3 TTTLVALLN---HGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQEN 173
T T A+LN GD+IV+ +YGGT L + + GI F D E + + +
Sbjct: 87 TATTYAVLNLTYAGDNIVALSTLYGGTYALFAHTLPQFGIEVRFVDPDRPEDLAKVVDDK 146
Query: 174 TKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSL 353
T++++ ET NP + VVDI A + A + G + +++DNT TPYL + D GAD+V+++
Sbjct: 147 TRLVFGETVGNPRINVVDIPAWAEAAHALG-LPLIIDNTAPTPYLVRAFDQGADVVVHAA 205
Query: 354 TKYMNGHSDVIMGAAIVNDK 413
TKY+ GH I G + + K
Sbjct: 206 TKYIGGHGTSIGGVIVDSGK 225
Score = 40.7 bits (91), Expect = 0.034
Identities = 21/61 (34%), Positives = 35/61 (57%)
Frame = +3
Query: 438 LQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSSLIIANWLEKHPKIVEVLHPXLXTHP 617
L+N G +P++ + + L+TL LRME H +++L +A +L H + V +P L P
Sbjct: 268 LRNTGGAT-TPMNSWLFLQGLETLHLRMERHSENALQVAEFLNGHEGVSWVNYPGLADSP 326
Query: 618 H 620
H
Sbjct: 327 H 327
>UniRef50_Q00ZR7 Cluster: Cystathionine gamma-synthase; n=1;
Ostreococcus tauri|Rep: Cystathionine gamma-synthase -
Ostreococcus tauri
Length = 653
Score = 93.9 bits (223), Expect = 3e-18
Identities = 53/133 (39%), Positives = 75/133 (56%), Gaps = 3/133 (2%)
Frame = +3
Query: 180 MIWIETPTNPLLKVVDI-EAIVKIARSRGDIIVVVDNTFLTPYLQKPL-DFGADIVMYSL 353
+IWIE NP + DI EA+ + RG V VD T LTP +PL FG IVM+S
Sbjct: 185 LIWIEPTANPTWDITDIGEAMQIVQEQRGVGCVCVDATVLTPICCQPLVQFGCHIVMHSA 244
Query: 354 TKYMNGHSDVIMGAAIVND-KAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHH 530
TKY+NGHSDV+ GA I + A +K+ + G D Y ++R ++TL +R+
Sbjct: 245 TKYLNGHSDVVAGALITKECDATWEKILHHRKMSGPTMGSFDAYLLSRGMRTLDVRVRRQ 304
Query: 531 KKSSLIIANWLEK 569
KS++ IA L++
Sbjct: 305 SKSAMYIAERLQE 317
>UniRef50_Q756K4 Cluster: AER250Cp; n=6; Saccharomycetales|Rep:
AER250Cp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 374
Score = 93.9 bits (223), Expect = 3e-18
Identities = 55/166 (33%), Positives = 90/166 (54%), Gaps = 5/166 (3%)
Frame = +3
Query: 138 NIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKP 317
++E+V E ++ IE+P NP +VD+ I A +G VV+D TF P LQ
Sbjct: 127 SLEEVSER-SEPGDLVHIESPINPYGTLVDVAGIAAAAHEKG-AYVVLDATFAPPPLQDR 184
Query: 318 LDFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRS 497
+ GAD+V++S TKY GHSD++ G V D A+ +LR + +G + ++ Y + RS
Sbjct: 185 WEQGADVVVHSCTKYFGGHSDLLGGVHAVRDAAVARQLRQDRVYLGTNIANLEAYLLIRS 244
Query: 498 LKTLALRMEHHKKSSLIIANWLEKHPK-----IVEVLHPXLXTHPH 620
++T+ +R+ S+ + +LE H +V+V H L T P+
Sbjct: 245 MRTMEMRVVRQSTSATKVVAYLESHKAEFGGVLVKVFHSSLQTEPY 290
>UniRef50_A6Q4H8 Cluster: O-acetylhomoserine sulfhydrylase; n=3;
Epsilonproteobacteria|Rep: O-acetylhomoserine
sulfhydrylase - Nitratiruptor sp. (strain SB155-2)
Length = 402
Score = 91.5 bits (217), Expect = 2e-17
Identities = 67/226 (29%), Positives = 114/226 (50%), Gaps = 23/226 (10%)
Frame = +3
Query: 9 TLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIW 188
T+ ++L GD + ++GG+ ++ +RLGI F + K+ + TKMI+
Sbjct: 90 TVTSMLESGDEVACIGGLFGGSYAFFKETAARLGIKARFYRADELPKISS----KTKMIY 145
Query: 189 IETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMN 368
E+ NP +++VD EA+ +A+ +I+ VVDNT LTP L P ++GAD+V+YS TK +
Sbjct: 146 CESIGNPNMQIVDFEALGMLAKEH-NILYVVDNT-LTPLLFNPFEYGADLVLYSTTKIIA 203
Query: 369 GHSDVIMGAAIVND----------------KAIGDKL-------RFLQNAMGIVPSPIDC 479
G S + GA + + +GDK R L++ G+ +
Sbjct: 204 GFSQALGGAVVFRSVREELVKNYPFMEKFVEKLGDKAYMGMMKKRALRD-FGMSQDAYES 262
Query: 480 YFVNRSLKTLALRMEHHKKSSLIIANWLEKHPKIVEVLHPXLXTHP 617
Y L+TLA R++ +S+ +A L+ + V+V+HP + P
Sbjct: 263 YLTMLGLETLAWRVQRVSQSAKEVALALQSY---VKVIHPAVSNDP 305
>UniRef50_P38716 Cluster: Uncharacterized trans-sulfuration enzyme
YHR112C; n=5; Saccharomycetales|Rep: Uncharacterized
trans-sulfuration enzyme YHR112C - Saccharomyces
cerevisiae (Baker's yeast)
Length = 378
Score = 91.1 bits (216), Expect = 2e-17
Identities = 45/144 (31%), Positives = 86/144 (59%)
Frame = +3
Query: 141 IEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPL 320
+E ++ E ++ +E+P NP DIE++ + A ++G +++V D+TF +P LQ
Sbjct: 128 LEDIEKCASEGD-IVHLESPVNPYGTSSDIESLARRAHAKGALLIV-DSTFASPPLQYAW 185
Query: 321 DFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSL 500
+FGADIV+YS TKY GHSD++ G +V ++A +L+ + +G + ++ + + RSL
Sbjct: 186 NFGADIVLYSATKYFGGHSDLLSGVLVVKEEATSRQLKDDRIYLGTNVANLESFMLLRSL 245
Query: 501 KTLALRMEHHKKSSLIIANWLEKH 572
+T +R+ +++ + +L H
Sbjct: 246 RTYEMRITKQSENATKLVRFLSDH 269
>UniRef50_Q28LE3 Cluster: Cys/Met metabolism
pyridoxal-phosphate-dependent enzyme; n=2;
Rhodobacteraceae|Rep: Cys/Met metabolism
pyridoxal-phosphate-dependent enzyme - Jannaschia sp.
(strain CCS1)
Length = 383
Score = 90.6 bits (215), Expect = 3e-17
Identities = 47/205 (22%), Positives = 101/205 (49%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
++TL+A + GD I + Y T R +++ G+ + E + + +
Sbjct: 88 SSTLLAFVKPGDRIACIEHAYPDTYRFFERMLRPFGVQIDYHPARAFEDDPDLLN-GVAI 146
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
++E+P++ + +++ + + A G + ++DN++ +P Q+PL G DIV++S +KY
Sbjct: 147 AYLESPSSVVFTPMNLARVAEHATRHGTV-TMIDNSWASPVFQRPLTLGIDIVLHSASKY 205
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
++GHSD + G + + I +G +P + + + R L+TL +RM H+ ++
Sbjct: 206 ISGHSDTVAGVVVSSHAHIARIRDLTLPLLGAKLAPFEAFLLTRGLRTLKVRMMQHQATA 265
Query: 543 LIIANWLEKHPKIVEVLHPXLXTHP 617
+ + L P++ + P P
Sbjct: 266 DLFVDRLAAVPQVRRINSPGANAVP 290
>UniRef50_A7INF9 Cluster: O-acetylhomoserine
aminocarboxypropyltransferase; n=2;
Alphaproteobacteria|Rep: O-acetylhomoserine
aminocarboxypropyltransferase - Xanthobacter sp. (strain
Py2)
Length = 467
Score = 90.6 bits (215), Expect = 3e-17
Identities = 47/127 (37%), Positives = 70/127 (55%)
Frame = +3
Query: 21 LLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWIETP 200
LL GD ++S +YGG+ G N + D +I + A+ TK I+ E+
Sbjct: 104 LLTPGDEFIASRKLYGGSINQFNHAFKSFGWNVVWADPDDISSFEKAVTPKTKAIFTESI 163
Query: 201 TNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNGHSD 380
NP V DI AI +A+ G + ++VDNT TPYL +P+ GADIV++S TK++ GH +
Sbjct: 164 ANPGGVVTDIAAISAVAKKAG-VPLIVDNTLATPYLWQPIRHGADIVIHSATKFLGGHGN 222
Query: 381 VIMGAAI 401
I G +
Sbjct: 223 SIGGVIV 229
>UniRef50_A7S3X8 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 343
Score = 90.2 bits (214), Expect = 4e-17
Identities = 45/116 (38%), Positives = 72/116 (62%), Gaps = 1/116 (0%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
+T L++LL GDH+V+ VY GT LL+ V+ R GI T ++E + A++ +TK+
Sbjct: 91 STALLSLLKAGDHVVAPKIVYSGTLALLQTVLPRYGIEVTLVTGDSMESYQEAVKPSTKV 150
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGD-IIVVVDNTFLTPYLQKPLDFGADIVMY 347
I+ ETP NP + V+D+EA ++ S G+ + +VD+TF +P+ Q PL A +Y
Sbjct: 151 IYGETPCNPTMAVLDLEAFAQLGMSLGEGVATMVDSTFGSPFNQAPLRHAAAAALY 206
>UniRef50_A1CUZ3 Cluster: Homocysteine synthase, putative; n=1;
Neosartorya fischeri NRRL 181|Rep: Homocysteine
synthase, putative - Neosartorya fischeri (strain ATCC
1020 / DSM 3700 / NRRL 181)(Aspergillus fischerianus
(strain ATCC 1020 / DSM 3700 / NRRL 181))
Length = 429
Score = 89.8 bits (213), Expect = 6e-17
Identities = 48/129 (37%), Positives = 73/129 (56%), Gaps = 1/129 (0%)
Frame = +3
Query: 9 TLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIW 188
TL+AL GD+IV+S V+GGT + + +LGI F E + ++ TK I+
Sbjct: 108 TLMALAGVGDNIVASSTVHGGTYHQFKVLAPQLGIECRFVASNEPEDFRALLEGKTKFIF 167
Query: 189 IETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTF-LTPYLQKPLDFGADIVMYSLTKYM 365
+E+ +NP V D EA+ I S G + ++ DNTF Y +P++ GADIV+YS K++
Sbjct: 168 VESISNPKYTVPDFEALADITHSHG-VPLICDNTFGCAGYYCRPIEHGADIVVYSARKWI 226
Query: 366 NGHSDVIMG 392
GH + G
Sbjct: 227 GGHGTTLGG 235
>UniRef50_Q8J0B2 Cluster: Homocysteine synthase-like protein; n=2;
Neotyphodium uncinatum|Rep: Homocysteine synthase-like
protein - Neotyphodium uncinatum
Length = 473
Score = 86.6 bits (205), Expect = 5e-16
Identities = 43/132 (32%), Positives = 74/132 (56%), Gaps = 1/132 (0%)
Frame = +3
Query: 9 TLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIW 188
T++AL GD+ VSS V+ GT + ++GI F + A+ + TK +W
Sbjct: 110 TVMALAGVGDNFVSSFHVHAGTFHQFESLAKQMGIECRFVKSRDPADFAAAIDDKTKFVW 169
Query: 189 IETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTF-LTPYLQKPLDFGADIVMYSLTKYM 365
+ET +NP ++D+EA+ + ++G I ++ DNTF Y +P++ G DIV++S TK++
Sbjct: 170 LETISNPGNVILDLEAVSMVCHTKG-IPLICDNTFGCAGYFCRPINHGVDIVVHSATKWI 228
Query: 366 NGHSDVIMGAAI 401
GH + G +
Sbjct: 229 GGHGTTVGGVIV 240
Score = 37.5 bits (83), Expect = 0.31
Identities = 18/47 (38%), Positives = 28/47 (59%), Gaps = 1/47 (2%)
Frame = +3
Query: 498 LKTLALRMEHHKKSSLIIANWLEKHPKIVEVLHPXLXTHP-HTXXLK 635
L++LA+R E H +++ IA+WL +HP + V + HP H LK
Sbjct: 301 LESLAVRCERHAQNAAKIADWLREHPLVAWVSYVGHPNHPDHQGALK 347
>UniRef50_A1D936 Cluster: Cystathionine gamma-synthase; n=21;
Ascomycota|Rep: Cystathionine gamma-synthase -
Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL
181)(Aspergillus fischerianus (strain ATCC 1020 / DSM
3700 / NRRL 181))
Length = 409
Score = 85.8 bits (203), Expect = 9e-16
Identities = 47/130 (36%), Positives = 73/130 (56%)
Frame = +3
Query: 180 MIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTK 359
+I +ETP NP +I A A SRG ++V D+TF P LQ P +GAD++M+S +K
Sbjct: 148 VILLETPVNPQGTAFNIAAYADKAHSRGAYLIV-DSTFAPPGLQDPFIWGADLIMHSGSK 206
Query: 360 YMNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKS 539
Y GHSDV+ G K KL + +G V ++ + RSL+TL +R++ +
Sbjct: 207 YFGGHSDVLCGVLATQRKDWAKKLFQDRLFLGSVMGNMESWLGVRSLRTLEIRVQRQSSN 266
Query: 540 SLIIANWLEK 569
+ + +WL+K
Sbjct: 267 AANLVSWLDK 276
>UniRef50_A7DHV1 Cluster: O-acetylhomoserine
aminocarboxypropyltransferase precursor; n=2;
Methylobacterium extorquens PA1|Rep: O-acetylhomoserine
aminocarboxypropyltransferase precursor -
Methylobacterium extorquens PA1
Length = 448
Score = 84.6 bits (200), Expect = 2e-15
Identities = 43/127 (33%), Positives = 74/127 (58%)
Frame = +3
Query: 12 LVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKMIWI 191
++ L+ GD V+S ++GG+ L+R++ R + F E + A+ TK I
Sbjct: 97 MMTLMQTGDAYVASPRLFGGSLGLMRRLEGRYDLTPQFAADLTPEAFEAAITPQTKAIIC 156
Query: 192 ETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKYMNG 371
E+ NP V+DIE I +A+ G + +V+DNT +P L +P+++GADI+++S +K++ G
Sbjct: 157 ESIVNPCATVMDIEGIAAVAKRHG-LPLVIDNTLASPALIRPIEYGADIIVHSTSKFLGG 215
Query: 372 HSDVIMG 392
VI G
Sbjct: 216 SGQVIGG 222
Score = 36.7 bits (81), Expect = 0.55
Identities = 16/47 (34%), Positives = 28/47 (59%)
Frame = +3
Query: 465 SPIDCYFVNRSLKTLALRMEHHKKSSLIIANWLEKHPKIVEVLHPXL 605
SP++ + ++TL LRME H ++ +A +L+ HP + V +P L
Sbjct: 280 SPMNAFLTLTGIETLPLRMERHCANAKAVAAYLKDHPAVDWVSYPAL 326
>UniRef50_Q64XN5 Cluster: O-acetylhomoserine sulfhydrylase; n=3;
Bacteroides|Rep: O-acetylhomoserine sulfhydrylase -
Bacteroides fragilis
Length = 411
Score = 83.8 bits (198), Expect = 4e-15
Identities = 62/225 (27%), Positives = 110/225 (48%), Gaps = 20/225 (8%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
+ L+ L + G ++V+S ++G T L+ + G+ F D T E+VK + +T
Sbjct: 90 SNALITLASAGANVVTSKHLFGNTYSFLKSTLEAFGVEVRFCDLTCPEEVKQQIDGDTCA 149
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
+++E TNP L+V D++A+ IA G + ++ D T + ++ DFG DI + S TKY
Sbjct: 150 LFLEVITNPQLEVADLKALADIAHKAG-VPLLADTTAIPFHVFHATDFGVDIEIVSSTKY 208
Query: 363 MNGHSDVIMG----------------AAIVND---KAIGDKLR-FLQNAMGIVPSPIDCY 482
++G + I G AA+ D +A KLR + +G +P Y
Sbjct: 209 ISGGATCIGGLIIDYGTFDWEHSAKLAALSADTGKEAFTVKLRKEVHRNLGAYMTPQVAY 268
Query: 483 FVNRSLKTLALRMEHHKKSSLIIANWLEKHPKIVEVLHPXLXTHP 617
L+T+ +R ++ L +A L++ P+I V + L ++P
Sbjct: 269 MQTLGLETMEVRFARQAETCLKLAQCLQELPEIESVNYTGLESNP 313
>UniRef50_A5BR77 Cluster: Putative uncharacterized protein; n=1;
Vitis vinifera|Rep: Putative uncharacterized protein -
Vitis vinifera (Grape)
Length = 400
Score = 83.8 bits (198), Expect = 4e-15
Identities = 48/157 (30%), Positives = 88/157 (56%), Gaps = 3/157 (1%)
Frame = +3
Query: 177 KMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLT 356
K+++ E NP+L V ++ + ++A +G + VVVDNTF P + P GAD+V++S++
Sbjct: 147 KVLYFEAIANPVLSVANVPELCRVAHDKG-LTVVVDNTF-APMVMSPAKLGADVVVHSIS 204
Query: 357 KYMNGHSDVIMGAAIVNDKAIGDKLRFLQNA---MGIVPSPIDCYFVNRSLKTLALRMEH 527
K+++G +D+I GA K + + Q A +G +P + ++ + L LRM+
Sbjct: 205 KFISGGADIIAGAVCGPAKLVNSMMDLHQGALMLLGPTMNPKVAFELSERIPHLGLRMKE 264
Query: 528 HKKSSLIIANWLEKHPKIVEVLHPXLXTHPHTXXLKN 638
H + +L A ++K ++V++P L HP LK+
Sbjct: 265 HCRRALEYATRMKKLG--LKVIYPGLEGHPDHTVLKS 299
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 631,217,280
Number of Sequences: 1657284
Number of extensions: 11687360
Number of successful extensions: 34119
Number of sequences better than 10.0: 387
Number of HSP's better than 10.0 without gapping: 32595
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 33684
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 55371905986
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -