Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= brP-0388
(700 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
S52784-1|AAB24700.1| 405|Homo sapiens cystathionine gamma-lyase... 250 4e-66
BT006882-1|AAP35528.1| 405|Homo sapiens cystathionase (cystathi... 250 4e-66
BC015807-1|AAH15807.1| 405|Homo sapiens cystathionase (cystathi... 250 4e-66
AL354872-2|CAC12902.1| 405|Homo sapiens cystathionase (cystathi... 250 4e-66
AK223376-1|BAD97096.1| 405|Homo sapiens cystathionase isoform 1... 250 4e-66
S52028-1|AAB24699.1| 361|Homo sapiens cystathionine gamma-lyase... 138 1e-43
AL354872-1|CAC12901.1| 361|Homo sapiens cystathionase (cystathi... 138 1e-43
X81086-1|CAA56990.1| 1078|Homo sapiens Calcium-sensing receptor ... 30 9.1
U20760-1|AAA86504.1| 1088|Homo sapiens extracellular calcium-sen... 30 9.1
U20759-1|AAA86503.1| 1078|Homo sapiens parathyroid cell calcium-... 30 9.1
S83176-1|AAB46873.1| 1078|Homo sapiens calcium-sensing receptor ... 30 9.1
S81755-1|AAD14370.1| 266|Homo sapiens calcium receptor|CaR prot... 30 9.1
D50855-1|BAA09453.1| 1078|Homo sapiens Ca-sensing receptor protein. 30 9.1
DQ327728-1|ABD04096.1| 501|Homo sapiens calcium sensing recepto... 30 9.1
DQ088967-1|AAY68221.1| 1078|Homo sapiens calcium-sensing recepto... 30 9.1
BC112236-1|AAI12237.1| 1078|Homo sapiens calcium-sensing recepto... 30 9.1
BC104999-1|AAI05000.1| 1078|Homo sapiens calcium-sensing recepto... 30 9.1
AY259116-1|AAP20759.1| 501|Homo sapiens calcium sensing recepto... 30 9.1
>S52784-1|AAB24700.1| 405|Homo sapiens cystathionine gamma-lyase
protein.
Length = 405
Score = 250 bits (612), Expect = 4e-66
Identities = 113/211 (53%), Positives = 149/211 (70%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
T T+ LL GD I+ DDVYGGTNR RQV S G+ +F D + I+ ++ A+ TK+
Sbjct: 94 TVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETKL 153
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
+WIETPTNP KV+DIE I GDII+VVDNTF++PY Q+PL GADI MYS TKY
Sbjct: 154 VWIETPTNPTQKVIDIEGCAHIVHKHGDIILVVDNTFMSPYFQRPLALGADISMYSATKY 213
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
MNGHSDV+MG VN +++ ++LRFLQN++G VPSPIDCY NR LKTL +RME H K+
Sbjct: 214 MNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNG 273
Query: 543 LIIANWLEKHPKIVEVLHPXLXTHPHTXXLK 635
+ +A +LE +P + +V++P L +HP +K
Sbjct: 274 MAVAQFLESNPWVEKVIYPGLPSHPQHELVK 304
>BT006882-1|AAP35528.1| 405|Homo sapiens cystathionase
(cystathionine gamma-lyase) protein.
Length = 405
Score = 250 bits (612), Expect = 4e-66
Identities = 113/211 (53%), Positives = 149/211 (70%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
T T+ LL GD I+ DDVYGGTNR RQV S G+ +F D + I+ ++ A+ TK+
Sbjct: 94 TVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETKL 153
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
+WIETPTNP KV+DIE I GDII+VVDNTF++PY Q+PL GADI MYS TKY
Sbjct: 154 VWIETPTNPTQKVIDIEGCAHIVHKHGDIILVVDNTFMSPYFQRPLALGADISMYSATKY 213
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
MNGHSDV+MG VN +++ ++LRFLQN++G VPSPIDCY NR LKTL +RME H K+
Sbjct: 214 MNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNG 273
Query: 543 LIIANWLEKHPKIVEVLHPXLXTHPHTXXLK 635
+ +A +LE +P + +V++P L +HP +K
Sbjct: 274 MAVAQFLESNPWVEKVIYPGLPSHPQHELVK 304
>BC015807-1|AAH15807.1| 405|Homo sapiens cystathionase
(cystathionine gamma-lyase) protein.
Length = 405
Score = 250 bits (612), Expect = 4e-66
Identities = 113/211 (53%), Positives = 149/211 (70%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
T T+ LL GD I+ DDVYGGTNR RQV S G+ +F D + I+ ++ A+ TK+
Sbjct: 94 TVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETKL 153
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
+WIETPTNP KV+DIE I GDII+VVDNTF++PY Q+PL GADI MYS TKY
Sbjct: 154 VWIETPTNPTQKVIDIEGCAHIVHKHGDIILVVDNTFMSPYFQRPLALGADISMYSATKY 213
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
MNGHSDV+MG VN +++ ++LRFLQN++G VPSPIDCY NR LKTL +RME H K+
Sbjct: 214 MNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNG 273
Query: 543 LIIANWLEKHPKIVEVLHPXLXTHPHTXXLK 635
+ +A +LE +P + +V++P L +HP +K
Sbjct: 274 MAVAQFLESNPWVEKVIYPGLPSHPQHELVK 304
>AL354872-2|CAC12902.1| 405|Homo sapiens cystathionase
(cystathionine gamma-lyase) protein.
Length = 405
Score = 250 bits (612), Expect = 4e-66
Identities = 113/211 (53%), Positives = 149/211 (70%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
T T+ LL GD I+ DDVYGGTNR RQV S G+ +F D + I+ ++ A+ TK+
Sbjct: 94 TVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETKL 153
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
+WIETPTNP KV+DIE I GDII+VVDNTF++PY Q+PL GADI MYS TKY
Sbjct: 154 VWIETPTNPTQKVIDIEGCAHIVHKHGDIILVVDNTFMSPYFQRPLALGADISMYSATKY 213
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
MNGHSDV+MG VN +++ ++LRFLQN++G VPSPIDCY NR LKTL +RME H K+
Sbjct: 214 MNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNG 273
Query: 543 LIIANWLEKHPKIVEVLHPXLXTHPHTXXLK 635
+ +A +LE +P + +V++P L +HP +K
Sbjct: 274 MAVAQFLESNPWVEKVIYPGLPSHPQHELVK 304
>AK223376-1|BAD97096.1| 405|Homo sapiens cystathionase isoform 1
variant protein.
Length = 405
Score = 250 bits (612), Expect = 4e-66
Identities = 113/211 (53%), Positives = 149/211 (70%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTKM 182
T T+ LL GD I+ DDVYGGTNR RQV S G+ +F D + I+ ++ A+ TK+
Sbjct: 94 TVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETKL 153
Query: 183 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQKPLDFGADIVMYSLTKY 362
+WIETPTNP KV+DIE I GDII+VVDNTF++PY Q+PL GADI MYS TKY
Sbjct: 154 VWIETPTNPTQKVIDIEGCAHIVHKHGDIILVVDNTFMSPYFQRPLALGADISMYSATKY 213
Query: 363 MNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPIDCYFVNRSLKTLALRMEHHKKSS 542
MNGHSDV+MG VN +++ ++LRFLQN++G VPSPIDCY NR LKTL +RME H K+
Sbjct: 214 MNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNG 273
Query: 543 LIIANWLEKHPKIVEVLHPXLXTHPHTXXLK 635
+ +A +LE +P + +V++P L +HP +K
Sbjct: 274 MAVAQFLESNPWVEKVIYPGLPSHPQHELVK 304
>S52028-1|AAB24699.1| 361|Homo sapiens cystathionine gamma-lyase
protein.
Length = 361
Score = 138 bits (333), Expect(2) = 1e-43
Identities = 61/114 (53%), Positives = 84/114 (73%)
Frame = +3
Query: 294 LTPYLQKPLDFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPI 473
+TP ++PL GADI MYS TKYMNGHSDV+MG VN +++ ++LRFLQN++G VPSPI
Sbjct: 147 ITPETKRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPI 206
Query: 474 DCYFVNRSLKTLALRMEHHKKSSLIIANWLEKHPKIVEVLHPXLXTHPHTXXLK 635
DCY NR LKTL +RME H K+ + +A +LE +P + +V++P L +HP +K
Sbjct: 207 DCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVK 260
Score = 58.8 bits (136), Expect(2) = 1e-43
Identities = 27/59 (45%), Positives = 36/59 (61%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTK 179
T T+ LL GD I+ DDVYGGTNR RQV S G+ +F D + I+ ++ A+ TK
Sbjct: 94 TVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETK 152
>AL354872-1|CAC12901.1| 361|Homo sapiens cystathionase
(cystathionine gamma-lyase) protein.
Length = 361
Score = 138 bits (333), Expect(2) = 1e-43
Identities = 61/114 (53%), Positives = 84/114 (73%)
Frame = +3
Query: 294 LTPYLQKPLDFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGDKLRFLQNAMGIVPSPI 473
+TP ++PL GADI MYS TKYMNGHSDV+MG VN +++ ++LRFLQN++G VPSPI
Sbjct: 147 ITPETKRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPI 206
Query: 474 DCYFVNRSLKTLALRMEHHKKSSLIIANWLEKHPKIVEVLHPXLXTHPHTXXLK 635
DCY NR LKTL +RME H K+ + +A +LE +P + +V++P L +HP +K
Sbjct: 207 DCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVK 260
Score = 58.8 bits (136), Expect(2) = 1e-43
Identities = 27/59 (45%), Positives = 36/59 (61%)
Frame = +3
Query: 3 TTTLVALLNHGDHIVSSDDVYGGTNRLLRQVVSRLGINTTFTDFTNIEKVKNAMQENTK 179
T T+ LL GD I+ DDVYGGTNR RQV S G+ +F D + I+ ++ A+ TK
Sbjct: 94 TVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETK 152
>X81086-1|CAA56990.1| 1078|Homo sapiens Calcium-sensing receptor
protein.
Length = 1078
Score = 29.9 bits (64), Expect = 9.1
Identities = 16/49 (32%), Positives = 31/49 (63%), Gaps = 2/49 (4%)
Frame = -1
Query: 304 YGVKKVLSTTTIM--SPRLLAIFTIASMSTTFNNGFVGVSIQIILVFSC 164
+G+ VL + I+ + R+L +F A + T+F+ + G+++Q +LVF C
Sbjct: 684 FGISFVLCISCILVKTNRVLLVFE-AKIPTSFHRKWWGLNLQFLLVFLC 731
>U20760-1|AAA86504.1| 1088|Homo sapiens extracellular
calcium-sensing receptor protein.
Length = 1088
Score = 29.9 bits (64), Expect = 9.1
Identities = 16/49 (32%), Positives = 31/49 (63%), Gaps = 2/49 (4%)
Frame = -1
Query: 304 YGVKKVLSTTTIM--SPRLLAIFTIASMSTTFNNGFVGVSIQIILVFSC 164
+G+ VL + I+ + R+L +F A + T+F+ + G+++Q +LVF C
Sbjct: 694 FGISFVLCISCILVKTNRVLLVFE-AKIPTSFHRKWWGLNLQFLLVFLC 741
>U20759-1|AAA86503.1| 1078|Homo sapiens parathyroid cell
calcium-sensing receptor protein.
Length = 1078
Score = 29.9 bits (64), Expect = 9.1
Identities = 16/49 (32%), Positives = 31/49 (63%), Gaps = 2/49 (4%)
Frame = -1
Query: 304 YGVKKVLSTTTIM--SPRLLAIFTIASMSTTFNNGFVGVSIQIILVFSC 164
+G+ VL + I+ + R+L +F A + T+F+ + G+++Q +LVF C
Sbjct: 684 FGISFVLCISCILVKTNRVLLVFE-AKIPTSFHRKWWGLNLQFLLVFLC 731
>S83176-1|AAB46873.1| 1078|Homo sapiens calcium-sensing receptor
long isoform protein.
Length = 1078
Score = 29.9 bits (64), Expect = 9.1
Identities = 16/49 (32%), Positives = 31/49 (63%), Gaps = 2/49 (4%)
Frame = -1
Query: 304 YGVKKVLSTTTIM--SPRLLAIFTIASMSTTFNNGFVGVSIQIILVFSC 164
+G+ VL + I+ + R+L +F A + T+F+ + G+++Q +LVF C
Sbjct: 684 FGISFVLCISCILVKTNRVLLVFE-AKIPTSFHRKWWGLNLQFLLVFLC 731
>S81755-1|AAD14370.1| 266|Homo sapiens calcium receptor|CaR
protein.
Length = 266
Score = 29.9 bits (64), Expect = 9.1
Identities = 16/49 (32%), Positives = 31/49 (63%), Gaps = 2/49 (4%)
Frame = -1
Query: 304 YGVKKVLSTTTIM--SPRLLAIFTIASMSTTFNNGFVGVSIQIILVFSC 164
+G+ VL + I+ + R+L +F A + T+F+ + G+++Q +LVF C
Sbjct: 42 FGISFVLCISCILVKTNRVLLVFE-AKIPTSFHRKWWGLNLQFLLVFLC 89
>D50855-1|BAA09453.1| 1078|Homo sapiens Ca-sensing receptor protein.
Length = 1078
Score = 29.9 bits (64), Expect = 9.1
Identities = 16/49 (32%), Positives = 31/49 (63%), Gaps = 2/49 (4%)
Frame = -1
Query: 304 YGVKKVLSTTTIM--SPRLLAIFTIASMSTTFNNGFVGVSIQIILVFSC 164
+G+ VL + I+ + R+L +F A + T+F+ + G+++Q +LVF C
Sbjct: 684 FGISFVLCISCILVKTNRVLLVFE-AKIPTSFHRKWWGLNLQFLLVFLC 731
>DQ327728-1|ABD04096.1| 501|Homo sapiens calcium sensing receptor
protein.
Length = 501
Score = 29.9 bits (64), Expect = 9.1
Identities = 16/49 (32%), Positives = 31/49 (63%), Gaps = 2/49 (4%)
Frame = -1
Query: 304 YGVKKVLSTTTIM--SPRLLAIFTIASMSTTFNNGFVGVSIQIILVFSC 164
+G+ VL + I+ + R+L +F A + T+F+ + G+++Q +LVF C
Sbjct: 107 FGISFVLCISCILVKTNRVLLVFE-AKIPTSFHRKWWGLNLQFLLVFLC 154
>DQ088967-1|AAY68221.1| 1078|Homo sapiens calcium-sensing receptor
(hypocalciuric hypercalcemia 1, severe neonatal hyperp
protein.
Length = 1078
Score = 29.9 bits (64), Expect = 9.1
Identities = 16/49 (32%), Positives = 31/49 (63%), Gaps = 2/49 (4%)
Frame = -1
Query: 304 YGVKKVLSTTTIM--SPRLLAIFTIASMSTTFNNGFVGVSIQIILVFSC 164
+G+ VL + I+ + R+L +F A + T+F+ + G+++Q +LVF C
Sbjct: 684 FGISFVLCISCILVKTNRVLLVFE-AKIPTSFHRKWWGLNLQFLLVFLC 731
>BC112236-1|AAI12237.1| 1078|Homo sapiens calcium-sensing receptor
protein.
Length = 1078
Score = 29.9 bits (64), Expect = 9.1
Identities = 16/49 (32%), Positives = 31/49 (63%), Gaps = 2/49 (4%)
Frame = -1
Query: 304 YGVKKVLSTTTIM--SPRLLAIFTIASMSTTFNNGFVGVSIQIILVFSC 164
+G+ VL + I+ + R+L +F A + T+F+ + G+++Q +LVF C
Sbjct: 684 FGISFVLCISCILVKTNRVLLVFE-AKIPTSFHRKWWGLNLQFLLVFLC 731
>BC104999-1|AAI05000.1| 1078|Homo sapiens calcium-sensing receptor
(hypocalciuric hypercalcemia 1, severe neonatal hyperp
protein.
Length = 1078
Score = 29.9 bits (64), Expect = 9.1
Identities = 16/49 (32%), Positives = 31/49 (63%), Gaps = 2/49 (4%)
Frame = -1
Query: 304 YGVKKVLSTTTIM--SPRLLAIFTIASMSTTFNNGFVGVSIQIILVFSC 164
+G+ VL + I+ + R+L +F A + T+F+ + G+++Q +LVF C
Sbjct: 684 FGISFVLCISCILVKTNRVLLVFE-AKIPTSFHRKWWGLNLQFLLVFLC 731
>AY259116-1|AAP20759.1| 501|Homo sapiens calcium sensing receptor
protein.
Length = 501
Score = 29.9 bits (64), Expect = 9.1
Identities = 16/49 (32%), Positives = 31/49 (63%), Gaps = 2/49 (4%)
Frame = -1
Query: 304 YGVKKVLSTTTIM--SPRLLAIFTIASMSTTFNNGFVGVSIQIILVFSC 164
+G+ VL + I+ + R+L +F A + T+F+ + G+++Q +LVF C
Sbjct: 107 FGISFVLCISCILVKTNRVLLVFE-AKIPTSFHRKWWGLNLQFLLVFLC 154
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 88,990,122
Number of Sequences: 237096
Number of extensions: 1615098
Number of successful extensions: 3689
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 3615
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3689
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8063224416
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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