Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= brP-0304
(750 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X69433-1|CAA49208.1| 452|Homo sapiens isocitrate dehydrogenase... 393 e-109
BC071828-1|AAH71828.1| 452|Homo sapiens isocitrate dehydrogenas... 393 e-109
BC009244-1|AAH09244.1| 452|Homo sapiens isocitrate dehydrogenas... 393 e-109
AK222916-1|BAD96636.1| 452|Homo sapiens isocitrate dehydrogenas... 391 e-108
CR541695-1|CAG46496.1| 414|Homo sapiens IDH1 protein. 387 e-107
CR536499-1|CAG38738.1| 414|Homo sapiens IDH1 protein. 387 e-107
BC093020-1|AAH93020.1| 414|Homo sapiens isocitrate dehydrogenas... 387 e-107
BC012846-1|AAH12846.1| 414|Homo sapiens IDH1 protein protein. 387 e-107
AF113917-1|AAD29284.1| 414|Homo sapiens NADP+-dependent isocitr... 387 e-107
AC016697-3|AAX93221.1| 414|Homo sapiens unknown protein. 387 e-107
AF020038-1|AAD02918.1| 414|Homo sapiens NADP-dependent isocitra... 385 e-106
BX537411-1|CAD97653.1| 414|Homo sapiens hypothetical protein pr... 384 e-106
CR533522-1|CAG38553.1| 414|Homo sapiens IDH1 protein. 383 e-106
DQ403082-1|ABD77215.1| 371|Homo sapiens isocitrate dehydrogenas... 360 3e-99
U52144-1|AAC50455.1| 419|Homo sapiens isocitrate dehydrogenase ... 354 2e-97
U62389-1|AAB17375.1| 154|Homo sapiens putative cytosolic NADP-d... 234 2e-61
AK090454-1|BAC03435.1| 708|Homo sapiens FLJ00375 protein protein. 37 0.089
BC030775-1|AAH30775.1| 941|Homo sapiens ARTS-1 protein protein. 32 2.5
AY358590-1|AAQ88953.1| 941|Homo sapiens ARTS-1 protein. 32 2.5
AY028807-1|AAK37778.1| 948|Homo sapiens adipocyte-derived leuci... 32 2.5
AY028806-1|AAK37777.1| 948|Homo sapiens adipocyte-derived leuci... 32 2.5
AF222340-1|AAF34664.1| 941|Homo sapiens type 1 tumor necrosis f... 32 2.5
AF183569-1|AAF20384.1| 941|Homo sapiens aminopeptidase PILS pro... 32 2.5
AF106037-1|AAF07395.1| 941|Homo sapiens adipocyte-derived leuci... 32 2.5
AB011097-1|BAA25451.2| 951|Homo sapiens KIAA0525 protein protein. 32 2.5
>X69433-1|CAA49208.1| 452|Homo sapiens isocitrate dehydrogenase
(NADP+) protein.
Length = 452
Score = 393 bits (967), Expect = e-109
Identities = 178/247 (72%), Positives = 205/247 (82%), Gaps = 1/247 (0%)
Frame = +2
Query: 11 MDGDEMTRIMWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAILKHNVGIK 190
MDGDEMTRI+W IKE+LI P+V + YFDLGLP+RD TDDQVTIDSA A K++V +K
Sbjct: 53 MDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSALATQKYSVAVK 112
Query: 191 CATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGWTKPIVIGR 370
CATITPDE RVEEFKLKKMW SPNGTIRNILGGTVFREPI+C++IPR+VPGWTKPI IGR
Sbjct: 113 CATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTKPITIGR 172
Query: 371 HAHGDQYKAQDFVVPKPGKVELVYTTRDGT-TERRVLYDFKTPGVAMGMYNTDESIRSFA 547
HAHGDQYKA DFV + G ++V+T +DG+ + +Y+F GV MGMYNTDESI FA
Sbjct: 173 HAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFA 232
Query: 548 HSSFQVALQKKWPLYLSTKNTILKRYDGRFKDIFEEVFQSDYKTKFDEAKIWYEHRLIDD 727
HS FQ A+QKKWPLY+STKNTILK YDGRFKDIF+E+F YKT FD+ KIWYEHRLIDD
Sbjct: 233 HSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDD 292
Query: 728 MVAQAIK 748
MVAQ +K
Sbjct: 293 MVAQVLK 299
>BC071828-1|AAH71828.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial protein.
Length = 452
Score = 393 bits (967), Expect = e-109
Identities = 178/247 (72%), Positives = 205/247 (82%), Gaps = 1/247 (0%)
Frame = +2
Query: 11 MDGDEMTRIMWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAILKHNVGIK 190
MDGDEMTRI+W IKE+LI P+V + YFDLGLP+RD TDDQVTIDSA A K++V +K
Sbjct: 53 MDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSALATQKYSVAVK 112
Query: 191 CATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGWTKPIVIGR 370
CATITPDE RVEEFKLKKMW SPNGTIRNILGGTVFREPI+C++IPR+VPGWTKPI IGR
Sbjct: 113 CATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTKPITIGR 172
Query: 371 HAHGDQYKAQDFVVPKPGKVELVYTTRDGT-TERRVLYDFKTPGVAMGMYNTDESIRSFA 547
HAHGDQYKA DFV + G ++V+T +DG+ + +Y+F GV MGMYNTDESI FA
Sbjct: 173 HAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFA 232
Query: 548 HSSFQVALQKKWPLYLSTKNTILKRYDGRFKDIFEEVFQSDYKTKFDEAKIWYEHRLIDD 727
HS FQ A+QKKWPLY+STKNTILK YDGRFKDIF+E+F YKT FD+ KIWYEHRLIDD
Sbjct: 233 HSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDD 292
Query: 728 MVAQAIK 748
MVAQ +K
Sbjct: 293 MVAQVLK 299
>BC009244-1|AAH09244.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial protein.
Length = 452
Score = 393 bits (967), Expect = e-109
Identities = 178/247 (72%), Positives = 205/247 (82%), Gaps = 1/247 (0%)
Frame = +2
Query: 11 MDGDEMTRIMWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAILKHNVGIK 190
MDGDEMTRI+W IKE+LI P+V + YFDLGLP+RD TDDQVTIDSA A K++V +K
Sbjct: 53 MDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSALATQKYSVAVK 112
Query: 191 CATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGWTKPIVIGR 370
CATITPDE RVEEFKLKKMW SPNGTIRNILGGTVFREPI+C++IPR+VPGWTKPI IGR
Sbjct: 113 CATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTKPITIGR 172
Query: 371 HAHGDQYKAQDFVVPKPGKVELVYTTRDGT-TERRVLYDFKTPGVAMGMYNTDESIRSFA 547
HAHGDQYKA DFV + G ++V+T +DG+ + +Y+F GV MGMYNTDESI FA
Sbjct: 173 HAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFA 232
Query: 548 HSSFQVALQKKWPLYLSTKNTILKRYDGRFKDIFEEVFQSDYKTKFDEAKIWYEHRLIDD 727
HS FQ A+QKKWPLY+STKNTILK YDGRFKDIF+E+F YKT FD+ KIWYEHRLIDD
Sbjct: 233 HSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDD 292
Query: 728 MVAQAIK 748
MVAQ +K
Sbjct: 293 MVAQVLK 299
>AK222916-1|BAD96636.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial precursor variant protein.
Length = 452
Score = 391 bits (963), Expect = e-108
Identities = 177/247 (71%), Positives = 205/247 (82%), Gaps = 1/247 (0%)
Frame = +2
Query: 11 MDGDEMTRIMWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAILKHNVGIK 190
MDGDEMTRI+W IKE+LI P+V + YFDLGLP+RD TDDQVTIDSA A K++V +K
Sbjct: 53 MDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSALATQKYSVAVK 112
Query: 191 CATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGWTKPIVIGR 370
CATITPDE RVEEFKLKKMW SPNGTIRNILGGTVFREPI+C++IPR+VPGWTKPI IGR
Sbjct: 113 CATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTKPITIGR 172
Query: 371 HAHGDQYKAQDFVVPKPGKVELVYTTRDGT-TERRVLYDFKTPGVAMGMYNTDESIRSFA 547
HAHGDQYKA DFV + G ++V+T +DG+ + +Y+F GV MGMYNTDESI FA
Sbjct: 173 HAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFA 232
Query: 548 HSSFQVALQKKWPLYLSTKNTILKRYDGRFKDIFEEVFQSDYKTKFDEAKIWYEHRLIDD 727
HS FQ A+QKKWPLY+STKNTILK YDGRFKDIF+E+F Y+T FD+ KIWYEHRLIDD
Sbjct: 233 HSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYETDFDKNKIWYEHRLIDD 292
Query: 728 MVAQAIK 748
MVAQ +K
Sbjct: 293 MVAQVLK 299
>CR541695-1|CAG46496.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 387 bits (952), Expect = e-107
Identities = 176/248 (70%), Positives = 212/248 (85%), Gaps = 2/248 (0%)
Frame = +2
Query: 11 MDGDEMTRIMWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAILKHNVGIK 190
M GDEMTRI+W IKE+LIFPYV++D +DLG+ +RDAT+DQVT D+A AI KHNVG+K
Sbjct: 13 MQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVK 72
Query: 191 CATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGWTKPIVIGR 370
CATITPDE+RVEEFKLK+MW SPNGTIRNILGGTVFRE I+C++IPR+V GW KPI+IGR
Sbjct: 73 CATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGR 132
Query: 371 HAHGDQYKAQDFVVPKPGKVELVYTTRDGTTE-RRVLYDFKT-PGVAMGMYNTDESIRSF 544
HA+GDQY+A DFVVP PGKVE+ YT DGT + ++++F+ GVAMGMYN D+SI F
Sbjct: 133 HAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDF 192
Query: 545 AHSSFQVALQKKWPLYLSTKNTILKRYDGRFKDIFEEVFQSDYKTKFDEAKIWYEHRLID 724
AHSSFQ+AL K WPLYLSTKNTILK+YDGRFKDIF+E++ YK++F+ KIWYEHRLID
Sbjct: 193 AHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLID 252
Query: 725 DMVAQAIK 748
DMVAQA+K
Sbjct: 253 DMVAQAMK 260
>CR536499-1|CAG38738.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 387 bits (952), Expect = e-107
Identities = 176/248 (70%), Positives = 212/248 (85%), Gaps = 2/248 (0%)
Frame = +2
Query: 11 MDGDEMTRIMWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAILKHNVGIK 190
M GDEMTRI+W IKE+LIFPYV++D +DLG+ +RDAT+DQVT D+A AI KHNVG+K
Sbjct: 13 MQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVK 72
Query: 191 CATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGWTKPIVIGR 370
CATITPDE+RVEEFKLK+MW SPNGTIRNILGGTVFRE I+C++IPR+V GW KPI+IGR
Sbjct: 73 CATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGR 132
Query: 371 HAHGDQYKAQDFVVPKPGKVELVYTTRDGTTE-RRVLYDFKT-PGVAMGMYNTDESIRSF 544
HA+GDQY+A DFVVP PGKVE+ YT DGT + ++++F+ GVAMGMYN D+SI F
Sbjct: 133 HAYGDQYRATDFVVPGPGKVEMTYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDF 192
Query: 545 AHSSFQVALQKKWPLYLSTKNTILKRYDGRFKDIFEEVFQSDYKTKFDEAKIWYEHRLID 724
AHSSFQ+AL K WPLYLSTKNTILK+YDGRFKDIF+E++ YK++F+ KIWYEHRLID
Sbjct: 193 AHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLID 252
Query: 725 DMVAQAIK 748
DMVAQA+K
Sbjct: 253 DMVAQAMK 260
>BC093020-1|AAH93020.1| 414|Homo sapiens isocitrate dehydrogenase 1
(NADP+), soluble protein.
Length = 414
Score = 387 bits (952), Expect = e-107
Identities = 176/248 (70%), Positives = 212/248 (85%), Gaps = 2/248 (0%)
Frame = +2
Query: 11 MDGDEMTRIMWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAILKHNVGIK 190
M GDEMTRI+W IKE+LIFPYV++D +DLG+ +RDAT+DQVT D+A AI KHNVG+K
Sbjct: 13 MQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVK 72
Query: 191 CATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGWTKPIVIGR 370
CATITPDE+RVEEFKLK+MW SPNGTIRNILGGTVFRE I+C++IPR+V GW KPI+IGR
Sbjct: 73 CATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGR 132
Query: 371 HAHGDQYKAQDFVVPKPGKVELVYTTRDGTTE-RRVLYDFKT-PGVAMGMYNTDESIRSF 544
HA+GDQY+A DFVVP PGKVE+ YT DGT + ++++F+ GVAMGMYN D+SI F
Sbjct: 133 HAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDF 192
Query: 545 AHSSFQVALQKKWPLYLSTKNTILKRYDGRFKDIFEEVFQSDYKTKFDEAKIWYEHRLID 724
AHSSFQ+AL K WPLYLSTKNTILK+YDGRFKDIF+E++ YK++F+ KIWYEHRLID
Sbjct: 193 AHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLID 252
Query: 725 DMVAQAIK 748
DMVAQA+K
Sbjct: 253 DMVAQAMK 260
>BC012846-1|AAH12846.1| 414|Homo sapiens IDH1 protein protein.
Length = 414
Score = 387 bits (952), Expect = e-107
Identities = 176/248 (70%), Positives = 212/248 (85%), Gaps = 2/248 (0%)
Frame = +2
Query: 11 MDGDEMTRIMWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAILKHNVGIK 190
M GDEMTRI+W IKE+LIFPYV++D +DLG+ +RDAT+DQVT D+A AI KHNVG+K
Sbjct: 13 MQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVK 72
Query: 191 CATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGWTKPIVIGR 370
CATITPDE+RVEEFKLK+MW SPNGTIRNILGGTVFRE I+C++IPR+V GW KPI+IGR
Sbjct: 73 CATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGR 132
Query: 371 HAHGDQYKAQDFVVPKPGKVELVYTTRDGTTE-RRVLYDFKT-PGVAMGMYNTDESIRSF 544
HA+GDQY+A DFVVP PGKVE+ YT DGT + ++++F+ GVAMGMYN D+SI F
Sbjct: 133 HAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDF 192
Query: 545 AHSSFQVALQKKWPLYLSTKNTILKRYDGRFKDIFEEVFQSDYKTKFDEAKIWYEHRLID 724
AHSSFQ+AL K WPLYLSTKNTILK+YDGRFKDIF+E++ YK++F+ KIWYEHRLID
Sbjct: 193 AHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLID 252
Query: 725 DMVAQAIK 748
DMVAQA+K
Sbjct: 253 DMVAQAMK 260
>AF113917-1|AAD29284.1| 414|Homo sapiens NADP+-dependent isocitrate
dehydrogenase protein.
Length = 414
Score = 387 bits (952), Expect = e-107
Identities = 176/248 (70%), Positives = 212/248 (85%), Gaps = 2/248 (0%)
Frame = +2
Query: 11 MDGDEMTRIMWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAILKHNVGIK 190
M GDEMTRI+W IKE+LIFPYV++D +DLG+ +RDAT+DQVT D+A AI KHNVG+K
Sbjct: 13 MQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVK 72
Query: 191 CATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGWTKPIVIGR 370
CATITPDE+RVEEFKLK+MW SPNGTIRNILGGTVFRE I+C++IPR+V GW KPI+IGR
Sbjct: 73 CATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGR 132
Query: 371 HAHGDQYKAQDFVVPKPGKVELVYTTRDGTTE-RRVLYDFKT-PGVAMGMYNTDESIRSF 544
HA+GDQY+A DFVVP PGKVE+ YT DGT + ++++F+ GVAMGMYN D+SI F
Sbjct: 133 HAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDF 192
Query: 545 AHSSFQVALQKKWPLYLSTKNTILKRYDGRFKDIFEEVFQSDYKTKFDEAKIWYEHRLID 724
AHSSFQ+AL K WPLYLSTKNTILK+YDGRFKDIF+E++ YK++F+ KIWYEHRLID
Sbjct: 193 AHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLID 252
Query: 725 DMVAQAIK 748
DMVAQA+K
Sbjct: 253 DMVAQAMK 260
>AC016697-3|AAX93221.1| 414|Homo sapiens unknown protein.
Length = 414
Score = 387 bits (952), Expect = e-107
Identities = 176/248 (70%), Positives = 212/248 (85%), Gaps = 2/248 (0%)
Frame = +2
Query: 11 MDGDEMTRIMWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAILKHNVGIK 190
M GDEMTRI+W IKE+LIFPYV++D +DLG+ +RDAT+DQVT D+A AI KHNVG+K
Sbjct: 13 MQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVK 72
Query: 191 CATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGWTKPIVIGR 370
CATITPDE+RVEEFKLK+MW SPNGTIRNILGGTVFRE I+C++IPR+V GW KPI+IGR
Sbjct: 73 CATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGR 132
Query: 371 HAHGDQYKAQDFVVPKPGKVELVYTTRDGTTE-RRVLYDFKT-PGVAMGMYNTDESIRSF 544
HA+GDQY+A DFVVP PGKVE+ YT DGT + ++++F+ GVAMGMYN D+SI F
Sbjct: 133 HAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDF 192
Query: 545 AHSSFQVALQKKWPLYLSTKNTILKRYDGRFKDIFEEVFQSDYKTKFDEAKIWYEHRLID 724
AHSSFQ+AL K WPLYLSTKNTILK+YDGRFKDIF+E++ YK++F+ KIWYEHRLID
Sbjct: 193 AHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLID 252
Query: 725 DMVAQAIK 748
DMVAQA+K
Sbjct: 253 DMVAQAMK 260
>AF020038-1|AAD02918.1| 414|Homo sapiens NADP-dependent isocitrate
dehydrogenase protein.
Length = 414
Score = 385 bits (947), Expect = e-106
Identities = 176/248 (70%), Positives = 211/248 (85%), Gaps = 2/248 (0%)
Frame = +2
Query: 11 MDGDEMTRIMWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAILKHNVGIK 190
M GDEMTRI+W IKE+LIFPYV++D +DLG+ +RDAT+DQVT D+A AI KHNVG+K
Sbjct: 13 MQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVK 72
Query: 191 CATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGWTKPIVIGR 370
CATITPDE+RVEEFKLK+MW SPNGTIRNILGGTVFRE I+C++IPR+V GW KPI+IGR
Sbjct: 73 CATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGR 132
Query: 371 HAHGDQYKAQDFVVPKPGKVELVYTTRDGTTE-RRVLYDFKT-PGVAMGMYNTDESIRSF 544
HA+GDQY+A DFVVP PGKVE+ YT DGT + ++++F+ GVAMGMYN D+SI F
Sbjct: 133 HAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDF 192
Query: 545 AHSSFQVALQKKWPLYLSTKNTILKRYDGRFKDIFEEVFQSDYKTKFDEAKIWYEHRLID 724
AHSSFQ+AL K WPLYLSTKNTILK YDGRFKDIF+E++ YK++F+ KIWYEHRLID
Sbjct: 193 AHSSFQMALSKGWPLYLSTKNTILKIYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLID 252
Query: 725 DMVAQAIK 748
DMVAQA+K
Sbjct: 253 DMVAQAMK 260
>BX537411-1|CAD97653.1| 414|Homo sapiens hypothetical protein
protein.
Length = 414
Score = 384 bits (946), Expect = e-106
Identities = 176/248 (70%), Positives = 207/248 (83%), Gaps = 2/248 (0%)
Frame = +2
Query: 11 MDGDEMTRIMWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAILKHNVGIK 190
M GDEMTRI+W IKE+LIFPYV++D +DLG+ +RDAT+DQVT D+A AI KHNVG+K
Sbjct: 13 MQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVK 72
Query: 191 CATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGWTKPIVIGR 370
CATITPDE+RVEEFKLK+MW SPNGTIRNILGGTVFRE I+C++IPR+V GW KPI+IGR
Sbjct: 73 CATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGR 132
Query: 371 HAHGDQYKAQDFVVPKPGKVELVYTTRDGTTERRVLYDFKT--PGVAMGMYNTDESIRSF 544
HA+GDQY+A DFVVP PGKVE+ YT DGT + L GVAMGMYN D+SI F
Sbjct: 133 HAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNSEGGGGVAMGMYNQDKSIEDF 192
Query: 545 AHSSFQVALQKKWPLYLSTKNTILKRYDGRFKDIFEEVFQSDYKTKFDEAKIWYEHRLID 724
AHSSFQ+AL K WPLYLSTKNTILK+YDGRFKDIF+E++ YK++F+ KIWYEHRLID
Sbjct: 193 AHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLID 252
Query: 725 DMVAQAIK 748
DMVAQA+K
Sbjct: 253 DMVAQAMK 260
>CR533522-1|CAG38553.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 383 bits (942), Expect = e-106
Identities = 174/248 (70%), Positives = 211/248 (85%), Gaps = 2/248 (0%)
Frame = +2
Query: 11 MDGDEMTRIMWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAILKHNVGIK 190
M GDEMTRI+W IKE+LI PYV++D +DLG+ +RDAT+DQVT D+A AI KHNVG+K
Sbjct: 13 MQGDEMTRIIWELIKEKLIIPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVK 72
Query: 191 CATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGWTKPIVIGR 370
CATITPDE+RVEEFKLK+MW SPNGTIRNILGGTVFRE I+C++IPR+V GW +PI+IGR
Sbjct: 73 CATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVEPIIIGR 132
Query: 371 HAHGDQYKAQDFVVPKPGKVELVYTTRDGTTE-RRVLYDFKT-PGVAMGMYNTDESIRSF 544
HA+GDQY+A DFVVP PGKVE+ YT DGT + ++++F+ GVAMGMYN D+SI F
Sbjct: 133 HAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDF 192
Query: 545 AHSSFQVALQKKWPLYLSTKNTILKRYDGRFKDIFEEVFQSDYKTKFDEAKIWYEHRLID 724
AHSSFQ+AL K WPLYLSTKNTILK+YDGRFKDIF+E++ YK++F+ KIWYEHRLID
Sbjct: 193 AHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLID 252
Query: 725 DMVAQAIK 748
DMVAQA+K
Sbjct: 253 DMVAQAMK 260
>DQ403082-1|ABD77215.1| 371|Homo sapiens isocitrate dehydrogenase 1
protein.
Length = 371
Score = 360 bits (886), Expect = 3e-99
Identities = 164/231 (70%), Positives = 198/231 (85%), Gaps = 2/231 (0%)
Frame = +2
Query: 62 LIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAILKHNVGIKCATITPDEQRVEEFKLK 241
LIFPYV++D +DLG+ +RDAT+DQVT D+A AI KHNVG+KCATITPDE+RVEEFKLK
Sbjct: 1 LIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLK 60
Query: 242 KMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGWTKPIVIGRHAHGDQYKAQDFVVPKP 421
+MW SPNGTIRNILGGTVFRE I+C++IPR+V GW KPI+IGRHA+GDQY+A DFVVP P
Sbjct: 61 QMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGP 120
Query: 422 GKVELVYTTRDGTTE-RRVLYDFKT-PGVAMGMYNTDESIRSFAHSSFQVALQKKWPLYL 595
GKVE+ YT DGT + ++++F+ GVAMGMYN D+SI FAHSSFQ+AL K WPLYL
Sbjct: 121 GKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYL 180
Query: 596 STKNTILKRYDGRFKDIFEEVFQSDYKTKFDEAKIWYEHRLIDDMVAQAIK 748
STKNTILK+YDGRFKDIF+E++ YK++F+ KIWYEHRLIDDMVAQA+K
Sbjct: 181 STKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMK 231
>U52144-1|AAC50455.1| 419|Homo sapiens isocitrate dehydrogenase
protein.
Length = 419
Score = 354 bits (870), Expect = 2e-97
Identities = 161/223 (72%), Positives = 184/223 (82%), Gaps = 1/223 (0%)
Frame = +2
Query: 83 VDCLYFDLGLPHRDATDDQVTIDSAHAILKHNVGIKCATITPDEQRVEEFKLKKMWLSPN 262
V YFDLGLP+RD TDDQVTIDSA A K++V +KCATITPDE RVEEFKLKKMW SPN
Sbjct: 44 VQLKYFDLGLPNRDQTDDQVTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPN 103
Query: 263 GTIRNILGGTVFREPILCQSIPRVVPGWTKPIVIGRHAHGDQYKAQDFVVPKPGKVELVY 442
GTIRNI GGTVFREPI+C++IPR+VPGWTKPI IGRHAHGDQYKA DFV + G ++V+
Sbjct: 104 GTIRNIHGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVF 163
Query: 443 TTRDGT-TERRVLYDFKTPGVAMGMYNTDESIRSFAHSSFQVALQKKWPLYLSTKNTILK 619
T +DG+ + +Y+F GV MGMYNTDESI FAHS FQ A+QKKWPLY+STKNTILK
Sbjct: 164 TPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILK 223
Query: 620 RYDGRFKDIFEEVFQSDYKTKFDEAKIWYEHRLIDDMVAQAIK 748
YDGRFKDIF+E+F YKT FD+ KIWYEHRLIDDMVAQ +K
Sbjct: 224 AYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVLK 266
>U62389-1|AAB17375.1| 154|Homo sapiens putative cytosolic
NADP-dependent isocitrate dehydrogenase protein.
Length = 154
Score = 234 bits (573), Expect = 2e-61
Identities = 106/154 (68%), Positives = 127/154 (82%), Gaps = 2/154 (1%)
Frame = +2
Query: 272 RNILGGTVFREPILCQSIPRVVPGWTKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTR 451
RNILGGTVF E I+C++IPR+V GW KPI+IGRHA+GDQY+A DFVVP PGKVE+ YT
Sbjct: 1 RNILGGTVFXEAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPS 60
Query: 452 DGTTERRVL-YDFKTPG-VAMGMYNTDESIRSFAHSSFQVALQKKWPLYLSTKNTILKRY 625
DGT + L ++F+ G VAMGMYN D+SI FAHSSFQ+AL K WPLYLSTKNTILK+Y
Sbjct: 61 DGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKY 120
Query: 626 DGRFKDIFEEVFQSDYKTKFDEAKIWYEHRLIDD 727
DGRFKDIF+E++ YK++F+ KIWYEHRLIDD
Sbjct: 121 DGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDD 154
>AK090454-1|BAC03435.1| 708|Homo sapiens FLJ00375 protein protein.
Length = 708
Score = 36.7 bits (81), Expect = 0.089
Identities = 16/43 (37%), Positives = 21/43 (48%)
Frame = +2
Query: 326 PRVVPGWTKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTRD 454
PR GW +P + H H DQ +P PGK +L+ RD
Sbjct: 20 PRAFKGWARPWLAQCHLHADQQPRAMHRMPDPGKFKLLEQARD 62
>BC030775-1|AAH30775.1| 941|Homo sapiens ARTS-1 protein protein.
Length = 941
Score = 31.9 bits (69), Expect = 2.5
Identities = 15/47 (31%), Positives = 24/47 (51%)
Frame = +2
Query: 560 QVALQKKWPLYLSTKNTILKRYDGRFKDIFEEVFQSDYKTKFDEAKI 700
Q+AL PL + T++ Y G + F ++S Y+TK E +I
Sbjct: 130 QIALLAPEPLLVGLPYTVVIHYAGNLSETFHGFYKSTYRTKEGELRI 176
>AY358590-1|AAQ88953.1| 941|Homo sapiens ARTS-1 protein.
Length = 941
Score = 31.9 bits (69), Expect = 2.5
Identities = 15/47 (31%), Positives = 24/47 (51%)
Frame = +2
Query: 560 QVALQKKWPLYLSTKNTILKRYDGRFKDIFEEVFQSDYKTKFDEAKI 700
Q+AL PL + T++ Y G + F ++S Y+TK E +I
Sbjct: 130 QIALLAPEPLLVGLPYTVVIHYAGNLSETFHGFYKSTYRTKEGELRI 176
>AY028807-1|AAK37778.1| 948|Homo sapiens adipocyte-derived leucine
aminopeptidase 2 isoform b protein.
Length = 948
Score = 31.9 bits (69), Expect = 2.5
Identities = 15/47 (31%), Positives = 24/47 (51%)
Frame = +2
Query: 560 QVALQKKWPLYLSTKNTILKRYDGRFKDIFEEVFQSDYKTKFDEAKI 700
Q+AL PL + T++ Y G + F ++S Y+TK E +I
Sbjct: 130 QIALLAPEPLLVGLPYTVVIHYAGNLSETFHGFYKSTYRTKEGELRI 176
>AY028806-1|AAK37777.1| 948|Homo sapiens adipocyte-derived leucine
aminopeptidase 2 isoform a protein.
Length = 948
Score = 31.9 bits (69), Expect = 2.5
Identities = 15/47 (31%), Positives = 24/47 (51%)
Frame = +2
Query: 560 QVALQKKWPLYLSTKNTILKRYDGRFKDIFEEVFQSDYKTKFDEAKI 700
Q+AL PL + T++ Y G + F ++S Y+TK E +I
Sbjct: 130 QIALLAPEPLLVGLPYTVVIHYAGNLSETFHGFYKSTYRTKEGELRI 176
>AF222340-1|AAF34664.1| 941|Homo sapiens type 1 tumor necrosis
factor receptor shedding aminopeptidase regulator
protein.
Length = 941
Score = 31.9 bits (69), Expect = 2.5
Identities = 15/47 (31%), Positives = 24/47 (51%)
Frame = +2
Query: 560 QVALQKKWPLYLSTKNTILKRYDGRFKDIFEEVFQSDYKTKFDEAKI 700
Q+AL PL + T++ Y G + F ++S Y+TK E +I
Sbjct: 130 QIALLAPEPLLVGLPYTVVIHYAGNLSETFHGFYKSTYRTKEGELRI 176
>AF183569-1|AAF20384.1| 941|Homo sapiens aminopeptidase PILS
protein.
Length = 941
Score = 31.9 bits (69), Expect = 2.5
Identities = 15/47 (31%), Positives = 24/47 (51%)
Frame = +2
Query: 560 QVALQKKWPLYLSTKNTILKRYDGRFKDIFEEVFQSDYKTKFDEAKI 700
Q+AL PL + T++ Y G + F ++S Y+TK E +I
Sbjct: 130 QIALLAPEPLLVGLPYTVVIHYAGNLSETFHGFYKSTYRTKEGELRI 176
>AF106037-1|AAF07395.1| 941|Homo sapiens adipocyte-derived leucine
aminopeptidase protein.
Length = 941
Score = 31.9 bits (69), Expect = 2.5
Identities = 15/47 (31%), Positives = 24/47 (51%)
Frame = +2
Query: 560 QVALQKKWPLYLSTKNTILKRYDGRFKDIFEEVFQSDYKTKFDEAKI 700
Q+AL PL + T++ Y G + F ++S Y+TK E +I
Sbjct: 130 QIALLAPEPLLVGLPYTVVIHYAGNLSETFHGFYKSTYRTKEGELRI 176
>AB011097-1|BAA25451.2| 951|Homo sapiens KIAA0525 protein protein.
Length = 951
Score = 31.9 bits (69), Expect = 2.5
Identities = 15/47 (31%), Positives = 24/47 (51%)
Frame = +2
Query: 560 QVALQKKWPLYLSTKNTILKRYDGRFKDIFEEVFQSDYKTKFDEAKI 700
Q+AL PL + T++ Y G + F ++S Y+TK E +I
Sbjct: 133 QIALLAPEPLLVGLPYTVVIHYAGNLSETFHGFYKSTYRTKEGELRI 179
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 118,474,264
Number of Sequences: 237096
Number of extensions: 2659141
Number of successful extensions: 6187
Number of sequences better than 10.0: 25
Number of HSP's better than 10.0 without gapping: 5991
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6171
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 9015132854
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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