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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= brP-0185
         (730 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

DQ993200-1|ABJ97705.1| 1104|Homo sapiens extended-synaptotagmin ...    83   1e-15
BC004998-1|AAH04998.1| 1104|Homo sapiens family with sequence si...    83   1e-15
AB018290-1|BAA34467.1| 1072|Homo sapiens KIAA0747 protein protein.     80   7e-15
DQ993202-1|ABJ97707.1|  886|Homo sapiens extended-synaptotagmin ...    80   9e-15
BC037292-1|AAH37292.1|  501|Homo sapiens FAM62C protein protein.       80   9e-15
AY368150-1|AAR89381.1|  893|Homo sapiens KIAA1228 protein protein.     77   7e-14
DQ993201-1|ABJ97706.1|  921|Homo sapiens extended-synaptotagmin ...    76   2e-13
AB033054-1|BAA86542.2|  843|Homo sapiens KIAA1228 protein protein.     76   2e-13
AB045125-1|BAD83600.1|  361|Homo sapiens KPG_013 protein protein.      33   1.4  
U10554-1|AAB92675.1|  532|Homo sapiens vesicular acetylcholine t...    31   5.6  
U09210-1|AAA20497.1|  532|Homo sapiens vesicular acetylcholine t...    31   5.6  
BC007765-1|AAH07765.1|  532|Homo sapiens solute carrier family 1...    31   5.6  

>DQ993200-1|ABJ97705.1| 1104|Homo sapiens extended-synaptotagmin 1
           protein.
          Length = 1104

 Score = 82.6 bits (195), Expect = 1e-15
 Identities = 49/151 (32%), Positives = 84/151 (55%), Gaps = 6/151 (3%)
 Frame = +3

Query: 273 PPGSDDGNSVFSMMYTFLKKVSIVGAVYLVGYMQWSVAWLIGPVILSVMRDQWRK-ENEY 449
           P G        +++ +F +++ ++  VYL G +  SV +++  + L +    WR+  +E 
Sbjct: 42  PAGPGAAGEALAVLTSFGRRLLVLIPVYLAGAVGLSVGFVLFGLALYL---GWRRVRDEK 98

Query: 450 KRNIAKVAALSSEKDVILARL-----DDLPSWVFFPDVERAEWLNRILLQVWPNVNSYAK 614
           +R++     L  +++ + A+       +LP+WV FPDVE+AEWLN+I+ QVWP +  Y +
Sbjct: 99  ERSLRAARQLLDDEEQLTAKTLYMSHRELPAWVSFPDVEKAEWLNKIVAQVWPFLGQYME 158

Query: 615 TLLXDLIEPAVAXSLANYKLSGFKFERMILG 707
            LL + + PAV  S  N  L  F F R+ LG
Sbjct: 159 KLLAETVAPAVRGS--NPHLQTFTFTRVELG 187


>BC004998-1|AAH04998.1| 1104|Homo sapiens family with sequence
           similarity 62 (C2 domain containing), member A protein.
          Length = 1104

 Score = 82.6 bits (195), Expect = 1e-15
 Identities = 49/151 (32%), Positives = 84/151 (55%), Gaps = 6/151 (3%)
 Frame = +3

Query: 273 PPGSDDGNSVFSMMYTFLKKVSIVGAVYLVGYMQWSVAWLIGPVILSVMRDQWRK-ENEY 449
           P G        +++ +F +++ ++  VYL G +  SV +++  + L +    WR+  +E 
Sbjct: 42  PAGPGAAGEALAVLTSFGRRLLVLIPVYLAGAVGLSVGFVLFGLALYL---GWRRVRDEK 98

Query: 450 KRNIAKVAALSSEKDVILARL-----DDLPSWVFFPDVERAEWLNRILLQVWPNVNSYAK 614
           +R++     L  +++ + A+       +LP+WV FPDVE+AEWLN+I+ QVWP +  Y +
Sbjct: 99  ERSLRAARQLLDDEEQLTAKTLYMSHRELPAWVSFPDVEKAEWLNKIVAQVWPFLGQYME 158

Query: 615 TLLXDLIEPAVAXSLANYKLSGFKFERMILG 707
            LL + + PAV  S  N  L  F F R+ LG
Sbjct: 159 KLLAETVAPAVRGS--NPHLQTFTFTRVELG 187


>AB018290-1|BAA34467.1| 1072|Homo sapiens KIAA0747 protein protein.
          Length = 1072

 Score = 80.2 bits (189), Expect = 7e-15
 Identities = 48/149 (32%), Positives = 83/149 (55%), Gaps = 6/149 (4%)
 Frame = +3

Query: 279 GSDDGNSVFSMMYTFLKKVSIVGAVYLVGYMQWSVAWLIGPVILSVMRDQWRK-ENEYKR 455
           G        +++ +F +++ ++  VYL G +  SV +++  + L +    WR+  +E +R
Sbjct: 2   GPGAAGEALAVLTSFGRRLLVLIPVYLAGAVGLSVGFVLFGLALYL---GWRRVRDEKER 58

Query: 456 NIAKVAALSSEKDVILARL-----DDLPSWVFFPDVERAEWLNRILLQVWPNVNSYAKTL 620
           ++     L  +++ + A+       +LP+WV FPDVE+AEWLN+I+ QVWP +  Y + L
Sbjct: 59  SLRAARQLLDDEEQLTAKTLYMSHRELPAWVSFPDVEKAEWLNKIVAQVWPFLGQYMEKL 118

Query: 621 LXDLIEPAVAXSLANYKLSGFKFERMILG 707
           L + + PAV  S  N  L  F F R+ LG
Sbjct: 119 LAETVAPAVRGS--NPHLQTFTFTRVELG 145


>DQ993202-1|ABJ97707.1|  886|Homo sapiens extended-synaptotagmin 3
           protein.
          Length = 886

 Score = 79.8 bits (188), Expect = 9e-15
 Identities = 47/141 (33%), Positives = 73/141 (51%), Gaps = 5/141 (3%)
 Frame = +3

Query: 318 TFLKKVSI-VGAVYLVGYMQWSVAWLIGPVILSVMRDQWRKENEYK--RNIAKVAALSSE 488
           TF+ +V   +G VYL GY+  S+ WL+   +L +    WR+    K  R  A    L +E
Sbjct: 37  TFVVRVLFYLGPVYLAGYLGLSITWLLLGALLWMW---WRRNRRGKLGRLAAAFEFLDNE 93

Query: 489 KDVILARL--DDLPSWVFFPDVERAEWLNRILLQVWPNVNSYAKTLLXDLIEPAVAXSLA 662
           ++ I   L    LP+W+ FPDVER EW N+I+ Q WP ++   ++   + +EP +     
Sbjct: 94  REFISRELRGQHLPAWIHFPDVERVEWANKIISQTWPYLSMIMESKFREKLEPKIREK-- 151

Query: 663 NYKLSGFKFERMILGTIAPRV 725
           +  L  F F ++  G   PRV
Sbjct: 152 SIHLRTFTFTKLYFGQKCPRV 172


>BC037292-1|AAH37292.1|  501|Homo sapiens FAM62C protein protein.
          Length = 501

 Score = 79.8 bits (188), Expect = 9e-15
 Identities = 47/141 (33%), Positives = 73/141 (51%), Gaps = 5/141 (3%)
 Frame = +3

Query: 318 TFLKKVSI-VGAVYLVGYMQWSVAWLIGPVILSVMRDQWRKENEYK--RNIAKVAALSSE 488
           TF+ +V   +G VYL GY+  S+ WL+   +L +    WR+    K  R  A    L +E
Sbjct: 37  TFVVRVLFYLGPVYLAGYLGLSITWLLLGALLWMW---WRRNRRGKLGRLAAAFEFLDNE 93

Query: 489 KDVILARL--DDLPSWVFFPDVERAEWLNRILLQVWPNVNSYAKTLLXDLIEPAVAXSLA 662
           ++ I   L    LP+W+ FPDVER EW N+I+ Q WP ++   ++   + +EP +     
Sbjct: 94  REFISRELRGQHLPAWIHFPDVERVEWANKIISQTWPYLSMIMESKFREKLEPKIREK-- 151

Query: 663 NYKLSGFKFERMILGTIAPRV 725
           +  L  F F ++  G   PRV
Sbjct: 152 SIHLRTFTFTKLYFGQKCPRV 172


>AY368150-1|AAR89381.1|  893|Homo sapiens KIAA1228 protein protein.
          Length = 893

 Score = 77.0 bits (181), Expect = 7e-14
 Identities = 53/159 (33%), Positives = 81/159 (50%), Gaps = 7/159 (4%)
 Frame = +3

Query: 252 GASKTALP--PGSDDGNSVFSMMYTFLKKVSIVGAVYLVGYMQWSVAWLIGPVILSVMRD 425
           GA   A P  PG      +  ++    +  +++  VY +GY+  S +W    V+L++   
Sbjct: 63  GAGGRAAPENPGGVLSVELPGLLAQLARSFALLLPVYALGYLGLSFSW----VLLALALL 118

Query: 426 QW-RKENEYK--RNIAKVAALSSEKDVIL--ARLDDLPSWVFFPDVERAEWLNRILLQVW 590
            W R+    K  R    +A L  E+ V+    R  DLP+WV FPD ERAEWLN+ +  +W
Sbjct: 119 AWCRRSRGLKALRLCRALALLEDEERVVRLGVRACDLPAWVHFPDTERAEWLNKTVKHMW 178

Query: 591 PNVNSYAKTLLXDLIEPAVAXSLANYKLSGFKFERMILG 707
           P +  + + L  + IEPAV    AN  LS F F ++ +G
Sbjct: 179 PFICQFIEKLFRETIEPAVRG--ANTHLSTFSFTKVDVG 215


>DQ993201-1|ABJ97706.1|  921|Homo sapiens extended-synaptotagmin 2
           protein.
          Length = 921

 Score = 75.8 bits (178), Expect = 2e-13
 Identities = 53/165 (32%), Positives = 85/165 (51%), Gaps = 13/165 (7%)
 Frame = +3

Query: 252 GASKTALPP---GSDDGNSVFS-----MMYTFLKKVSIVGAVYLVGYMQWSVAWLIGPVI 407
           G+++   PP   G ++   V S     ++    +  +++  VY +GY+  S +W    V+
Sbjct: 85  GSARAPSPPRPGGPENPGGVLSVELPGLLAQLARSFALLLPVYALGYLGLSFSW----VL 140

Query: 408 LSVMRDQW-RKENEYK--RNIAKVAALSSEKDVIL--ARLDDLPSWVFFPDVERAEWLNR 572
           L++    W R+    K  R    +A L  E+ V+    R  DLP+WV FPD ERAEWLN+
Sbjct: 141 LALALLAWCRRSRGLKALRLCRALALLEDEERVVRLGVRACDLPAWVHFPDTERAEWLNK 200

Query: 573 ILLQVWPNVNSYAKTLLXDLIEPAVAXSLANYKLSGFKFERMILG 707
            +  +WP +  + + L  + IEPAV    AN  LS F F ++ +G
Sbjct: 201 TVKHMWPFICQFIEKLFRETIEPAVRG--ANTHLSTFSFTKVDVG 243


>AB033054-1|BAA86542.2|  843|Homo sapiens KIAA1228 protein protein.
          Length = 843

 Score = 75.8 bits (178), Expect = 2e-13
 Identities = 53/165 (32%), Positives = 85/165 (51%), Gaps = 13/165 (7%)
 Frame = +3

Query: 252 GASKTALPP---GSDDGNSVFS-----MMYTFLKKVSIVGAVYLVGYMQWSVAWLIGPVI 407
           G+++   PP   G ++   V S     ++    +  +++  VY +GY+  S +W    V+
Sbjct: 7   GSARAPSPPRPGGPENPGGVLSVELPGLLAQLARSFALLLPVYALGYLGLSFSW----VL 62

Query: 408 LSVMRDQW-RKENEYK--RNIAKVAALSSEKDVIL--ARLDDLPSWVFFPDVERAEWLNR 572
           L++    W R+    K  R    +A L  E+ V+    R  DLP+WV FPD ERAEWLN+
Sbjct: 63  LALALLAWCRRSRGLKALRLCRALALLEDEERVVRLGVRACDLPAWVHFPDTERAEWLNK 122

Query: 573 ILLQVWPNVNSYAKTLLXDLIEPAVAXSLANYKLSGFKFERMILG 707
            +  +WP +  + + L  + IEPAV    AN  LS F F ++ +G
Sbjct: 123 TVKHMWPFICQFIEKLFRETIEPAVRG--ANTHLSTFSFTKVDVG 165


>AB045125-1|BAD83600.1|  361|Homo sapiens KPG_013 protein protein.
          Length = 361

 Score = 32.7 bits (71), Expect = 1.4
 Identities = 20/74 (27%), Positives = 36/74 (48%)
 Frame = +3

Query: 291 GNSVFSMMYTFLKKVSIVGAVYLVGYMQWSVAWLIGPVILSVMRDQWRKENEYKRNIAKV 470
           G +   ++  F   +    A+ LV  ++W+ AWL+GPV+  ++             I  +
Sbjct: 72  GATASLVLNLFCADLLFTSAIPLVLVVRWTEAWLLGPVVCHLLFYVMTMSGSV--TILTL 129

Query: 471 AALSSEKDVILARL 512
           AA+S E+ V + RL
Sbjct: 130 AAVSLERMVCIVRL 143


>U10554-1|AAB92675.1|  532|Homo sapiens vesicular acetylcholine
           transporter protein.
          Length = 532

 Score = 30.7 bits (66), Expect = 5.6
 Identities = 10/28 (35%), Positives = 21/28 (75%)
 Frame = +3

Query: 324 LKKVSIVGAVYLVGYMQWSVAWLIGPVI 407
           ++ VS+ G+VY +  + +SVA+ +GP++
Sbjct: 411 VRHVSVYGSVYAIADISYSVAYALGPIV 438


>U09210-1|AAA20497.1|  532|Homo sapiens vesicular acetylcholine
           transporter protein.
          Length = 532

 Score = 30.7 bits (66), Expect = 5.6
 Identities = 10/28 (35%), Positives = 21/28 (75%)
 Frame = +3

Query: 324 LKKVSIVGAVYLVGYMQWSVAWLIGPVI 407
           ++ VS+ G+VY +  + +SVA+ +GP++
Sbjct: 411 VRHVSVYGSVYAIADISYSVAYALGPIV 438


>BC007765-1|AAH07765.1|  532|Homo sapiens solute carrier family 18
           (vesicular acetylcholine), member 3 protein.
          Length = 532

 Score = 30.7 bits (66), Expect = 5.6
 Identities = 10/28 (35%), Positives = 21/28 (75%)
 Frame = +3

Query: 324 LKKVSIVGAVYLVGYMQWSVAWLIGPVI 407
           ++ VS+ G+VY +  + +SVA+ +GP++
Sbjct: 411 VRHVSVYGSVYAIADISYSVAYALGPIV 438


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 101,951,007
Number of Sequences: 237096
Number of extensions: 2119956
Number of successful extensions: 4668
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 4456
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4650
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8623170556
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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