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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= brP-0173
         (504 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

BC015936-1|AAH15936.1|  534|Homo sapiens ASH2L protein protein.       133   3e-31
AF056717-1|AAC13563.1|  501|Homo sapiens ash2l2 protein.              133   3e-31
AB022785-1|BAA74520.1|  628|Homo sapiens ASH2L protein.               133   3e-31
AB020982-1|BAA35127.1|  628|Homo sapiens ASH2L protein.               133   3e-31
AF056718-1|AAC13564.1|  628|Homo sapiens ash2l1 protein.              127   3e-29
BC132861-1|AAI32862.1|  276|Homo sapiens hypothetical protein LO...    36   0.11 
BC126240-1|AAI26241.1|  276|Homo sapiens hypothetical protein LO...    36   0.11 
AK123670-1|BAC85673.1|  276|Homo sapiens protein ( Homo sapiens ...    36   0.11 
AY210419-1|AAO34702.1| 3501|Homo sapiens CUB and sushi multiple ...    31   1.7  
AK128215-1|BAC87331.1|  516|Homo sapiens protein ( Homo sapiens ...    31   1.7  
AB114605-1|BAC82444.1| 3667|Homo sapiens CSMD3 protein isoform 2...    31   1.7  
AB114604-1|BAC82443.1| 3707|Homo sapiens CSMD3 protein isoform 1...    31   1.7  
AB067481-1|BAB67787.2| 2977|Homo sapiens KIAA1894 protein protein.     31   1.7  
BC051288-1|AAH51288.1|  470|Homo sapiens naked cuticle homolog 1...    30   5.3  
BC034003-1|AAH34003.1|  600|Homo sapiens PRR12 protein protein.        30   5.3  
AY061883-1|AAL32374.1|  470|Homo sapiens naked protein protein.        30   5.3  
AF358135-1|AAK57484.1|  470|Homo sapiens naked cuticle-1 protein.      30   5.3  
AB062886-1|BAB70500.1|  470|Homo sapiens Dvl-binding protein NKD...    30   5.3  
AB033031-1|BAA86519.1| 1217|Homo sapiens KIAA1205 protein protein.     30   5.3  
AB023162-1|BAA76789.2|  797|Homo sapiens KIAA0945 protein protein.     30   5.3  
AL583839-6|CAI12344.3| 2297|Homo sapiens WNK lysine deficient pr...    29   7.0  
AL390760-1|CAH73069.3| 2297|Homo sapiens WNK lysine deficient pr...    29   7.0  
AL354991-2|CAI14449.3| 2297|Homo sapiens WNK lysine deficient pr...    29   7.0  
AJ242724-1|CAB44308.5| 2297|Homo sapiens putative mitogen-activa...    29   7.0  

>BC015936-1|AAH15936.1|  534|Homo sapiens ASH2L protein protein.
          Length = 534

 Score =  133 bits (322), Expect = 3e-31
 Identities = 68/119 (57%), Positives = 82/119 (68%), Gaps = 1/119 (0%)
 Frame = +2

Query: 98  KGRQGKRRPAVGSAAETGAPIGKKGRNADV-TALKLPSHGYPTEHPFNKDGYRYILAEPD 274
           KGR  KR+   G    T     KK R+  + +A +LP HGYP EHPFNKDGYRYILAEPD
Sbjct: 200 KGRGAKRKQQDGGTTGTT----KKARSDPLFSAQRLPPHGYPLEHPFNKDGYRYILAEPD 255

Query: 275 PHAPFRQEFDESNEWSGKPIPGWLYRPLCPGGVLLALHDRAPQLRVAXDRLAVTGDRGY 451
           PHAP  ++  E + W+GKPIPG LYR      VLLALHDRAPQL+++ DRL V G++GY
Sbjct: 256 PHAPDPEKL-ELDCWAGKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVVGEKGY 313


>AF056717-1|AAC13563.1|  501|Homo sapiens ash2l2 protein.
          Length = 501

 Score =  133 bits (322), Expect = 3e-31
 Identities = 68/119 (57%), Positives = 82/119 (68%), Gaps = 1/119 (0%)
 Frame = +2

Query: 98  KGRQGKRRPAVGSAAETGAPIGKKGRNADV-TALKLPSHGYPTEHPFNKDGYRYILAEPD 274
           KGR  KR+   G    T     KK R+  + +A +LP HGYP EHPFNKDGYRYILAEPD
Sbjct: 200 KGRGAKRKQQDGGTTGTT----KKARSDPLFSAQRLPPHGYPLEHPFNKDGYRYILAEPD 255

Query: 275 PHAPFRQEFDESNEWSGKPIPGWLYRPLCPGGVLLALHDRAPQLRVAXDRLAVTGDRGY 451
           PHAP  ++  E + W+GKPIPG LYR      VLLALHDRAPQL+++ DRL V G++GY
Sbjct: 256 PHAPDPEKL-ELDCWAGKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVVGEKGY 313


>AB022785-1|BAA74520.1|  628|Homo sapiens ASH2L protein.
          Length = 628

 Score =  133 bits (322), Expect = 3e-31
 Identities = 68/119 (57%), Positives = 82/119 (68%), Gaps = 1/119 (0%)
 Frame = +2

Query: 98  KGRQGKRRPAVGSAAETGAPIGKKGRNADV-TALKLPSHGYPTEHPFNKDGYRYILAEPD 274
           KGR  KR+   G    T     KK R+  + +A +LP HGYP EHPFNKDGYRYILAEPD
Sbjct: 294 KGRGAKRKQQDGGTTGTT----KKARSDPLFSAQRLPPHGYPLEHPFNKDGYRYILAEPD 349

Query: 275 PHAPFRQEFDESNEWSGKPIPGWLYRPLCPGGVLLALHDRAPQLRVAXDRLAVTGDRGY 451
           PHAP  ++  E + W+GKPIPG LYR      VLLALHDRAPQL+++ DRL V G++GY
Sbjct: 350 PHAPDPEKL-ELDCWAGKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVVGEKGY 407


>AB020982-1|BAA35127.1|  628|Homo sapiens ASH2L protein.
          Length = 628

 Score =  133 bits (322), Expect = 3e-31
 Identities = 68/119 (57%), Positives = 82/119 (68%), Gaps = 1/119 (0%)
 Frame = +2

Query: 98  KGRQGKRRPAVGSAAETGAPIGKKGRNADV-TALKLPSHGYPTEHPFNKDGYRYILAEPD 274
           KGR  KR+   G    T     KK R+  + +A +LP HGYP EHPFNKDGYRYILAEPD
Sbjct: 294 KGRGAKRKQQDGGTTGTT----KKARSDPLFSAQRLPPHGYPLEHPFNKDGYRYILAEPD 349

Query: 275 PHAPFRQEFDESNEWSGKPIPGWLYRPLCPGGVLLALHDRAPQLRVAXDRLAVTGDRGY 451
           PHAP  ++  E + W+GKPIPG LYR      VLLALHDRAPQL+++ DRL V G++GY
Sbjct: 350 PHAPDPEKL-ELDCWAGKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVVGEKGY 407


>AF056718-1|AAC13564.1|  628|Homo sapiens ash2l1 protein.
          Length = 628

 Score =  127 bits (306), Expect = 3e-29
 Identities = 66/119 (55%), Positives = 80/119 (67%), Gaps = 1/119 (0%)
 Frame = +2

Query: 98  KGRQGKRRPAVGSAAETGAPIGKKGRNADV-TALKLPSHGYPTEHPFNKDGYRYILAEPD 274
           KGR  KR+   G    T     KK R+  + +A +LP HGYP EHPFNKDGYRYILAEPD
Sbjct: 294 KGRGAKRKQQDGGTTGTT----KKARSDPLFSAQRLPPHGYPLEHPFNKDGYRYILAEPD 349

Query: 275 PHAPFRQEFDESNEWSGKPIPGWLYRPLCPGGVLLALHDRAPQLRVAXDRLAVTGDRGY 451
           P AP  ++  E + W+GKPI G LYR      VLLALHDRAPQL+++ DRL V G++GY
Sbjct: 350 PQAPDPEKL-EIDCWAGKPISGDLYRACLYERVLLALHDRAPQLKISDDRLTVVGEKGY 407


>BC132861-1|AAI32862.1|  276|Homo sapiens hypothetical protein
           LOC339524 protein.
          Length = 276

 Score = 35.5 bits (78), Expect = 0.11
 Identities = 30/89 (33%), Positives = 38/89 (42%)
 Frame = +2

Query: 74  AVPLAGNVKGRQGKRRPAVGSAAETGAPIGKKGRNADVTALKLPSHGYPTEHPFNKDGYR 253
           A P +G   GR G RRP +G AA +G P    G  A        + G    HP+ + G R
Sbjct: 86  ASPRSGRGPGRGGGRRPRLG-AARSGCP----GAAA--------AGGPAVLHPWRRAGGR 132

Query: 254 YILAEPDPHAPFRQEFDESNEWSGKPIPG 340
              A P       + F   + WS  PIPG
Sbjct: 133 VRGASPPQGPQTARGFPLPSRWSSSPIPG 161


>BC126240-1|AAI26241.1|  276|Homo sapiens hypothetical protein
           LOC339524 protein.
          Length = 276

 Score = 35.5 bits (78), Expect = 0.11
 Identities = 30/89 (33%), Positives = 38/89 (42%)
 Frame = +2

Query: 74  AVPLAGNVKGRQGKRRPAVGSAAETGAPIGKKGRNADVTALKLPSHGYPTEHPFNKDGYR 253
           A P +G   GR G RRP +G AA +G P    G  A        + G    HP+ + G R
Sbjct: 86  ASPRSGRGPGRGGGRRPRLG-AARSGCP----GAAA--------AGGPAVLHPWRRAGGR 132

Query: 254 YILAEPDPHAPFRQEFDESNEWSGKPIPG 340
              A P       + F   + WS  PIPG
Sbjct: 133 VRGASPPQGPQTARGFPLPSRWSSSPIPG 161


>AK123670-1|BAC85673.1|  276|Homo sapiens protein ( Homo sapiens
           cDNA FLJ41676 fis, clone HCASM2002502. ).
          Length = 276

 Score = 35.5 bits (78), Expect = 0.11
 Identities = 30/89 (33%), Positives = 38/89 (42%)
 Frame = +2

Query: 74  AVPLAGNVKGRQGKRRPAVGSAAETGAPIGKKGRNADVTALKLPSHGYPTEHPFNKDGYR 253
           A P +G   GR G RRP +G AA +G P    G  A        + G    HP+ + G R
Sbjct: 86  ASPRSGRGPGRGGGRRPRLG-AARSGCP----GAAA--------AGGPAVLHPWRRAGGR 132

Query: 254 YILAEPDPHAPFRQEFDESNEWSGKPIPG 340
              A P       + F   + WS  PIPG
Sbjct: 133 VRGASPPQGPQTARGFPLPSRWSSSPIPG 161


>AY210419-1|AAO34702.1| 3501|Homo sapiens CUB and sushi multiple
            domains 3 protein.
          Length = 3501

 Score = 31.5 bits (68), Expect = 1.7
 Identities = 25/89 (28%), Positives = 37/89 (41%)
 Frame = +2

Query: 176  NADVTALKLPSHGYPTEHPFNKDGYRYILAEPDPHAPFRQEFDESNEWSGKPIPGWLYRP 355
            +A+V  + LPSHGY   +        + LA    H   R +    N W+GK        P
Sbjct: 3213 HANVVGMDLPSHGYTLIYTCQPG---FFLAGGTEHRVCRSD----NTWTGKV-------P 3258

Query: 356  LCPGGVLLALHDRAPQLRVAXDRLAVTGD 442
            +C  G  + + D  P L     +L+V  D
Sbjct: 3259 ICEAGSKILVKDPRPALGTPSPKLSVPDD 3287


>AK128215-1|BAC87331.1|  516|Homo sapiens protein ( Homo sapiens
           cDNA FLJ46347 fis, clone TESTI4047437. ).
          Length = 516

 Score = 31.5 bits (68), Expect = 1.7
 Identities = 15/32 (46%), Positives = 19/32 (59%)
 Frame = +1

Query: 196 ETALARLPHRASLQQRRLQIHLGGTRPARALQ 291
           E  LAR+P +  LQ RRL +HL   R   A+Q
Sbjct: 85  EGPLARVPAQVRLQVRRLPVHLAAARNVAAVQ 116


>AB114605-1|BAC82444.1| 3667|Homo sapiens CSMD3 protein isoform 2
            protein.
          Length = 3667

 Score = 31.5 bits (68), Expect = 1.7
 Identities = 25/89 (28%), Positives = 37/89 (41%)
 Frame = +2

Query: 176  NADVTALKLPSHGYPTEHPFNKDGYRYILAEPDPHAPFRQEFDESNEWSGKPIPGWLYRP 355
            +A+V  + LPSHGY   +        + LA    H   R +    N W+GK        P
Sbjct: 3379 HANVVGMDLPSHGYTLIYTCQPG---FFLAGGTEHRVCRSD----NTWTGKV-------P 3424

Query: 356  LCPGGVLLALHDRAPQLRVAXDRLAVTGD 442
            +C  G  + + D  P L     +L+V  D
Sbjct: 3425 ICEAGSKILVKDPRPALGTPSPKLSVPDD 3453


>AB114604-1|BAC82443.1| 3707|Homo sapiens CSMD3 protein isoform 1
            protein.
          Length = 3707

 Score = 31.5 bits (68), Expect = 1.7
 Identities = 25/89 (28%), Positives = 37/89 (41%)
 Frame = +2

Query: 176  NADVTALKLPSHGYPTEHPFNKDGYRYILAEPDPHAPFRQEFDESNEWSGKPIPGWLYRP 355
            +A+V  + LPSHGY   +        + LA    H   R +    N W+GK        P
Sbjct: 3419 HANVVGMDLPSHGYTLIYTCQPG---FFLAGGTEHRVCRSD----NTWTGKV-------P 3464

Query: 356  LCPGGVLLALHDRAPQLRVAXDRLAVTGD 442
            +C  G  + + D  P L     +L+V  D
Sbjct: 3465 ICEAGSKILVKDPRPALGTPSPKLSVPDD 3493


>AB067481-1|BAB67787.2| 2977|Homo sapiens KIAA1894 protein protein.
          Length = 2977

 Score = 31.5 bits (68), Expect = 1.7
 Identities = 25/89 (28%), Positives = 37/89 (41%)
 Frame = +2

Query: 176  NADVTALKLPSHGYPTEHPFNKDGYRYILAEPDPHAPFRQEFDESNEWSGKPIPGWLYRP 355
            +A+V  + LPSHGY   +        + LA    H   R +    N W+GK        P
Sbjct: 2689 HANVVGMDLPSHGYTLIYTCQPG---FFLAGGTEHRVCRSD----NTWTGKV-------P 2734

Query: 356  LCPGGVLLALHDRAPQLRVAXDRLAVTGD 442
            +C  G  + + D  P L     +L+V  D
Sbjct: 2735 ICEAGSKILVKDPRPALGTPSPKLSVPDD 2763


>BC051288-1|AAH51288.1|  470|Homo sapiens naked cuticle homolog 1
           (Drosophila) protein.
          Length = 470

 Score = 29.9 bits (64), Expect = 5.3
 Identities = 13/31 (41%), Positives = 16/31 (51%)
 Frame = +2

Query: 281 APFRQEFDESNEWSGKPIPGWLYRPLCPGGV 373
           +P    F  S  W+ K I  W+ R  CPGGV
Sbjct: 17  SPEGDSFAVSAAWARKGIEEWIGRQRCPGGV 47


>BC034003-1|AAH34003.1|  600|Homo sapiens PRR12 protein protein.
          Length = 600

 Score = 29.9 bits (64), Expect = 5.3
 Identities = 15/32 (46%), Positives = 16/32 (50%)
 Frame = +3

Query: 141 PRPGLPSARKAVTPMSPL*NCPRTATPPSIPS 236
           P PGLPSA    TP  PL       TPP  P+
Sbjct: 71  PLPGLPSANSNGTPEPPLLEEKPPPTPPPAPT 102


>AY061883-1|AAL32374.1|  470|Homo sapiens naked protein protein.
          Length = 470

 Score = 29.9 bits (64), Expect = 5.3
 Identities = 13/31 (41%), Positives = 16/31 (51%)
 Frame = +2

Query: 281 APFRQEFDESNEWSGKPIPGWLYRPLCPGGV 373
           +P    F  S  W+ K I  W+ R  CPGGV
Sbjct: 17  SPEGDSFAVSAAWARKGIEEWIGRQRCPGGV 47


>AF358135-1|AAK57484.1|  470|Homo sapiens naked cuticle-1 protein.
          Length = 470

 Score = 29.9 bits (64), Expect = 5.3
 Identities = 13/31 (41%), Positives = 16/31 (51%)
 Frame = +2

Query: 281 APFRQEFDESNEWSGKPIPGWLYRPLCPGGV 373
           +P    F  S  W+ K I  W+ R  CPGGV
Sbjct: 17  SPEGDSFAVSAAWARKGIEEWIGRQRCPGGV 47


>AB062886-1|BAB70500.1|  470|Homo sapiens Dvl-binding protein NKD1
           protein.
          Length = 470

 Score = 29.9 bits (64), Expect = 5.3
 Identities = 13/31 (41%), Positives = 16/31 (51%)
 Frame = +2

Query: 281 APFRQEFDESNEWSGKPIPGWLYRPLCPGGV 373
           +P    F  S  W+ K I  W+ R  CPGGV
Sbjct: 17  SPEGDSFAVSAAWARKGIEEWIGRQRCPGGV 47


>AB033031-1|BAA86519.1| 1217|Homo sapiens KIAA1205 protein protein.
          Length = 1217

 Score = 29.9 bits (64), Expect = 5.3
 Identities = 15/32 (46%), Positives = 16/32 (50%)
 Frame = +3

Query: 141 PRPGLPSARKAVTPMSPL*NCPRTATPPSIPS 236
           P PGLPSA    TP  PL       TPP  P+
Sbjct: 616 PLPGLPSANSNGTPEPPLLEEKPPPTPPPAPT 647


>AB023162-1|BAA76789.2|  797|Homo sapiens KIAA0945 protein protein.
          Length = 797

 Score = 29.9 bits (64), Expect = 5.3
 Identities = 17/49 (34%), Positives = 24/49 (48%), Gaps = 3/49 (6%)
 Frame = +3

Query: 114 SAGLRSAARPRPGLPSARKAVTPMSPL*NCPRTATPPS---IPSTKTVT 251
           +AG RS  +    LP A    +P  PL  CP  + PP+   +P  +T T
Sbjct: 494 AAGCRSLGQLEFPLPEAGHPASPAHPLLGCPVPSVPPAAEPVPHLQTPT 542


>AL583839-6|CAI12344.3| 2297|Homo sapiens WNK lysine deficient protein
            kinase 2 protein.
          Length = 2297

 Score = 29.5 bits (63), Expect = 7.0
 Identities = 15/38 (39%), Positives = 21/38 (55%), Gaps = 2/38 (5%)
 Frame = -1

Query: 171  PFLPMGA--PVSAALPTAGLRLPCLPFTLPASGTAIIS 64
            P LP+ +  P ++  P  GL LPCLP+   A G   +S
Sbjct: 1331 PPLPLSSLPPEASQGPCRGLTLPCLPWRRAACGAVFLS 1368


>AL390760-1|CAH73069.3| 2297|Homo sapiens WNK lysine deficient protein
            kinase 2 protein.
          Length = 2297

 Score = 29.5 bits (63), Expect = 7.0
 Identities = 15/38 (39%), Positives = 21/38 (55%), Gaps = 2/38 (5%)
 Frame = -1

Query: 171  PFLPMGA--PVSAALPTAGLRLPCLPFTLPASGTAIIS 64
            P LP+ +  P ++  P  GL LPCLP+   A G   +S
Sbjct: 1331 PPLPLSSLPPEASQGPCRGLTLPCLPWRRAACGAVFLS 1368


>AL354991-2|CAI14449.3| 2297|Homo sapiens WNK lysine deficient protein
            kinase 2 protein.
          Length = 2297

 Score = 29.5 bits (63), Expect = 7.0
 Identities = 15/38 (39%), Positives = 21/38 (55%), Gaps = 2/38 (5%)
 Frame = -1

Query: 171  PFLPMGA--PVSAALPTAGLRLPCLPFTLPASGTAIIS 64
            P LP+ +  P ++  P  GL LPCLP+   A G   +S
Sbjct: 1331 PPLPLSSLPPEASQGPCRGLTLPCLPWRRAACGAVFLS 1368


>AJ242724-1|CAB44308.5| 2297|Homo sapiens putative mitogen-activated
            protein kinase kinase kinase protein.
          Length = 2297

 Score = 29.5 bits (63), Expect = 7.0
 Identities = 15/38 (39%), Positives = 21/38 (55%), Gaps = 2/38 (5%)
 Frame = -1

Query: 171  PFLPMGA--PVSAALPTAGLRLPCLPFTLPASGTAIIS 64
            P LP+ +  P ++  P  GL LPCLP+   A G   +S
Sbjct: 1331 PPLPLSSLPPEASQGPCRGLTLPCLPWRRAACGAVFLS 1368


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 62,678,363
Number of Sequences: 237096
Number of extensions: 1384378
Number of successful extensions: 9321
Number of sequences better than 10.0: 24
Number of HSP's better than 10.0 without gapping: 8819
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 9310
length of database: 76,859,062
effective HSP length: 85
effective length of database: 56,705,902
effective search space used: 4649883964
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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