Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= brP-0123
(723 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_O75390 Cluster: Citrate synthase, mitochondrial precurs... 303 3e-81
UniRef50_P20115 Cluster: Citrate synthase 4, mitochondrial precu... 237 2e-61
UniRef50_Q9M1D3 Cluster: Citrate synthase 5, mitochondrial precu... 224 2e-57
UniRef50_A6S819 Cluster: Citrate synthase; n=1; Botryotinia fuck... 211 1e-53
UniRef50_Q4QDX3 Cluster: Probable citrate synthase, mitochondria... 198 1e-49
UniRef50_UPI00006CFBEC Cluster: Citrate synthase family protein;... 181 2e-44
UniRef50_UPI00006CBE2B Cluster: citrate synthase; n=1; Tetrahyme... 180 3e-44
UniRef50_A0DZ50 Cluster: Citrate synthase; n=6; Paramecium tetra... 180 3e-44
UniRef50_Q95TZ4 Cluster: Citrate synthase; n=1; Drosophila melan... 176 5e-43
UniRef50_Q6JGH9 Cluster: Citrate synthase; n=17; Desulfuromonada... 163 5e-39
UniRef50_P43635 Cluster: Citrate synthase 3; n=7; Saccharomyceta... 155 1e-36
UniRef50_UPI00015B4F54 Cluster: PREDICTED: hypothetical protein;... 146 4e-34
UniRef50_Q4N4H4 Cluster: Citrate synthase, putative; n=3; Piropl... 139 6e-32
UniRef50_UPI0000DB6B6F Cluster: PREDICTED: similar to citrate sy... 134 2e-30
UniRef50_A4ZVV6 Cluster: Mitochondrial citrate synthase 1; n=1; ... 132 6e-30
UniRef50_A5KE63 Cluster: Citrate synthase, mitochondrial, putati... 117 3e-25
UniRef50_UPI0000D9A0A8 Cluster: PREDICTED: similar to citrate sy... 81 3e-14
UniRef50_Q6MAA4 Cluster: Putative citrate (Si)-synthase; n=1; Ca... 48 2e-04
UniRef50_Q8F887 Cluster: Citrate synthase; n=4; Leptospira|Rep: ... 48 2e-04
UniRef50_Q8ZWP2 Cluster: Citrate synthase; n=7; Thermoproteaceae... 48 3e-04
UniRef50_Q9LXS7 Cluster: Citrate synthase 1, peroxisomal precurs... 47 5e-04
UniRef50_Q550V8 Cluster: Citrate synthase; n=3; Dictyostelium di... 45 0.002
UniRef50_O28929 Cluster: Citrate synthase; n=2; cellular organis... 45 0.002
UniRef50_Q8RV72 Cluster: Putative citrate synthetase; n=1; Arabi... 44 0.004
UniRef50_Q9LXS6 Cluster: Citrate synthase 2, peroxisomal precurs... 44 0.004
UniRef50_P56062 Cluster: Citrate synthase; n=43; Epsilonproteoba... 43 0.007
UniRef50_P45858 Cluster: Citrate synthase 3; n=19; Bacillaceae|R... 41 0.036
UniRef50_Q7W5Q6 Cluster: 2-methylcitrate synthase; n=122; Bacter... 40 0.047
UniRef50_A6ERK5 Cluster: Citrate synthase; n=1; unidentified eub... 40 0.047
UniRef50_Q56063 Cluster: 2-methylcitrate synthase; n=14; Enterob... 40 0.082
UniRef50_Q8NSL1 Cluster: 2-methylcitrate synthase 2; n=29; Bacte... 39 0.14
UniRef50_A7C184 Cluster: Citrate synthase; n=1; Beggiatoa sp. PS... 38 0.25
UniRef50_A6T3T1 Cluster: 2-methylcitrate synthase; n=60; Bacteri... 38 0.25
UniRef50_A4KFK1 Cluster: Citrate synthase I gltA2; n=1; Mycobact... 38 0.25
UniRef50_Q59977 Cluster: Citrate synthase; n=37; Bacteria|Rep: C... 38 0.25
UniRef50_Q10530 Cluster: Citrate synthase 1; n=288; cellular org... 38 0.25
UniRef50_A6CE34 Cluster: Citrate synthase; n=1; Planctomyces mar... 38 0.33
UniRef50_Q19T76 Cluster: GltA; n=1; Anaplasma phagocytophilum|Re... 37 0.58
UniRef50_Q7NZ52 Cluster: Citrate (Si)-synthase; n=4; Bacteria|Re... 36 0.77
UniRef50_Q2JTT9 Cluster: 2-methylcitrate synthase/citrate syntha... 35 1.8
UniRef50_Q86JM6 Cluster: Similar to Homo sapiens (Human). NPD010... 35 2.3
UniRef50_Q9WYC6 Cluster: Citrate synthase; n=2; Thermotoga|Rep: ... 34 3.1
UniRef50_Q9RWB2 Cluster: Citrate synthase; n=7; Deinococci|Rep: ... 34 3.1
UniRef50_A0RVR8 Cluster: Citrate synthase; n=4; cellular organis... 34 4.1
UniRef50_Q63TQ8 Cluster: Dihydrolipoamide succinyltransferase co... 33 5.4
UniRef50_Q4P943 Cluster: Predicted protein; n=1; Ustilago maydis... 33 5.4
UniRef50_Q2PPA5 Cluster: Geranylgeranyl diphosphate synthase; n=... 33 5.4
UniRef50_P42457 Cluster: Citrate synthase; n=10; Actinobacterida... 33 5.4
UniRef50_Q9XBT3 Cluster: PrpC; n=12; cellular organisms|Rep: Prp... 33 7.1
UniRef50_A2DLI0 Cluster: Putative uncharacterized protein; n=1; ... 33 9.4
UniRef50_Q0CQ68 Cluster: Predicted protein; n=1; Aspergillus ter... 33 9.4
>UniRef50_O75390 Cluster: Citrate synthase, mitochondrial precursor;
n=140; cellular organisms|Rep: Citrate synthase,
mitochondrial precursor - Homo sapiens (Human)
Length = 466
Score = 303 bits (744), Expect = 3e-81
Identities = 137/186 (73%), Positives = 160/186 (86%)
Frame = +1
Query: 166 PRXQEKIREFRKKHGSTKVGEVTVDMMYGGMRGIKGLVWETSVLDADEGIRFRGLSIPEC 345
P+ Q +I+ FR++HG T VG++TVDMMYGGMRG+KGLV+ETSVLD DEGIRFRG SIPEC
Sbjct: 42 PKEQARIKTFRQQHGKTVVGQITVDMMYGGMRGMKGLVYETSVLDPDEGIRFRGFSIPEC 101
Query: 346 QQQLPKAKGGEEPLPEGLFWLLVTGDIPTEAQAKALSKEWAARAELPAHVVTMLNNMPGK 525
Q+ LPKAKGGEEPLPEGLFWLLVTG IPTE Q LSKEWA RA LP+HVVTML+N P
Sbjct: 102 QKLLPKAKGGEEPLPEGLFWLLVTGHIPTEEQVSWLSKEWAKRAALPSHVVTMLDNFPTN 161
Query: 526 LHPMSQFSAAVTALNSESKFAKAYSXGVHKSKYWEYVYEDTMNLIAKLPVIAATIYRNVY 705
LHPMSQ SAAVTALNSES FA+AY+ G+ ++KYWE +YED+M+LIAKLP +AA IYRN+Y
Sbjct: 162 LHPMSQLSAAVTALNSESNFARAYAQGISRTKYWELIYEDSMDLIAKLPCVAAKIYRNLY 221
Query: 706 RDGKGI 723
R+G GI
Sbjct: 222 REGSGI 227
>UniRef50_P20115 Cluster: Citrate synthase 4, mitochondrial
precursor; n=27; Eukaryota|Rep: Citrate synthase 4,
mitochondrial precursor - Arabidopsis thaliana
(Mouse-ear cress)
Length = 474
Score = 237 bits (580), Expect = 2e-61
Identities = 100/186 (53%), Positives = 143/186 (76%)
Frame = +1
Query: 166 PRXQEKIREFRKKHGSTKVGEVTVDMMYGGMRGIKGLVWETSVLDADEGIRFRGLSIPEC 345
P Q+++++ + +HG ++G +TVDM+ GGMRG+ GL+WETS+LD +EGIRFRGLSIPEC
Sbjct: 50 PEQQDRLKKLKSEHGKVQLGNITVDMVIGGMRGMTGLLWETSLLDPEEGIRFRGLSIPEC 109
Query: 346 QQQLPKAKGGEEPLPEGLFWLLVTGDIPTEAQAKALSKEWAARAELPAHVVTMLNNMPGK 525
Q+ LP A+ G EPLPEGL WLL+TG +P++ Q +ALSK+ A RA +P +V ++ +P
Sbjct: 110 QKVLPTAQSGAEPLPEGLLWLLLTGKVPSKEQVEALSKDLANRAAVPDYVYNAIDALPST 169
Query: 526 LHPMSQFSAAVTALNSESKFAKAYSXGVHKSKYWEYVYEDTMNLIAKLPVIAATIYRNVY 705
HPM+QF++ V AL +S+F KAY G+HKSK+WE YED +NLIA++PV+AA +YR +Y
Sbjct: 170 AHPMTQFASGVMALQVQSEFQKAYENGIHKSKFWEPTYEDCLNLIARVPVVAAYVYRRMY 229
Query: 706 RDGKGI 723
++G I
Sbjct: 230 KNGDSI 235
>UniRef50_Q9M1D3 Cluster: Citrate synthase 5, mitochondrial
precursor; n=26; Eukaryota|Rep: Citrate synthase 5,
mitochondrial precursor - Arabidopsis thaliana
(Mouse-ear cress)
Length = 433
Score = 224 bits (547), Expect = 2e-57
Identities = 101/184 (54%), Positives = 138/184 (75%), Gaps = 1/184 (0%)
Frame = +1
Query: 166 PRXQEKIREFRKKHGSTKVGEVTVDMMYGGMRGIKGLVWETSVLDADEGIRFRGLSIPEC 345
P Q+++++ + + G VG +TVDM+ GGMRG+ GL+WETS+LDADEGIRFRG+SIPEC
Sbjct: 15 PEQQDRLKKLKSEQGKVPVGNITVDMVLGGMRGMTGLLWETSLLDADEGIRFRGMSIPEC 74
Query: 346 QQQLPKAKGGEEPLPEGLFWLLVTGDIPTEAQAKALSKEWAARAELPAHVVTMLNNMPGK 525
Q+ LP A+ GEEPLPE L WLL+TG +PT+ QA ALS E A RA +PA ++ +P
Sbjct: 75 QKILPSAESGEEPLPESLLWLLLTGKVPTKEQANALSTELAHRAAVPA-----IDALPST 129
Query: 526 LHPMSQFSAAVTALNSESKFAKAYSXG-VHKSKYWEYVYEDTMNLIAKLPVIAATIYRNV 702
HPM+QF++ V AL +S+F KAY G + KSKYWE +ED +NLIA++PV+A+ +YR +
Sbjct: 130 AHPMTQFASGVMALQVQSEFQKAYEQGDISKSKYWEPTFEDALNLIARVPVVASYVYRRM 189
Query: 703 YRDG 714
Y+DG
Sbjct: 190 YKDG 193
>UniRef50_A6S819 Cluster: Citrate synthase; n=1; Botryotinia
fuckeliana B05.10|Rep: Citrate synthase - Botryotinia
fuckeliana B05.10
Length = 534
Score = 211 bits (515), Expect = 1e-53
Identities = 99/191 (51%), Positives = 137/191 (71%)
Frame = +1
Query: 142 KVFSRKRFPRXQEKIREFRKKHGSTKVGEVTVDMMYGGMRGIKGLVWETSVLDADEGIRF 321
K ++ P +E +++ K +G+ +GEV ++ GGMRG+K +VWE SVLDADEGIRF
Sbjct: 69 KATFKECIPAKRELLKKV-KANGNKVIGEVKIENTIGGMRGLKAMVWEGSVLDADEGIRF 127
Query: 322 RGLSIPECQQQLPKAKGGEEPLPEGLFWLLVTGDIPTEAQAKALSKEWAARAELPAHVVT 501
G +I +CQ++LPK K G E LPE +FWLL+TG IP+ +Q + SKE A +A LP V
Sbjct: 128 HGRTIKDCQKELPKGKSGTEMLPEAMFWLLLTGQIPSTSQVRQFSKELAEQAALPDFVNK 187
Query: 502 MLNNMPGKLHPMSQFSAAVTALNSESKFAKAYSXGVHKSKYWEYVYEDTMNLIAKLPVIA 681
ML+N P LHPM+QF+ AV+AL+ SKFAK+Y GV+K+ YWE ++D+++L+AKLPVIA
Sbjct: 188 MLDNFPKDLHPMTQFAMAVSALSHTSKFAKSYEKGVNKADYWEPTFDDSISLLAKLPVIA 247
Query: 682 ATIYRNVYRDG 714
A IY+N Y G
Sbjct: 248 AKIYQNSYGGG 258
>UniRef50_Q4QDX3 Cluster: Probable citrate synthase, mitochondrial
precursor; n=9; Trypanosomatidae|Rep: Probable citrate
synthase, mitochondrial precursor - Leishmania major
Length = 470
Score = 198 bits (483), Expect = 1e-49
Identities = 98/191 (51%), Positives = 130/191 (68%), Gaps = 3/191 (1%)
Frame = +1
Query: 157 KRFPRXQEKIREFRKKHGSTKVGEVTVDMMYGGMRGIKGLVWETSVLDADEGIRFRGLSI 336
+R+ Q+KI + RKKHG K+ + T+D +YGGMRGI GLV+E S+LD EGIRFRGL+I
Sbjct: 31 RRWKEDQKKIDDLRKKHGHEKLCDATIDAVYGGMRGITGLVYEPSLLDPAEGIRFRGLTI 90
Query: 337 PECQQQLPKAKGGEEPLPEGLFWLLVTGDIPTEAQAKALSKEWAARA--ELPAHVVTMLN 510
ECQ+ LPKA GG+EPLPE +FWLL+TG++PTE Q + L+ E RA E A +
Sbjct: 91 LECQEMLPKAPGGKEPLPEAMFWLLMTGEVPTEEQVRGLNAELHRRADPEAIAAAQKAIA 150
Query: 511 NMPGKLHPMSQFSAAVTALNSESKFAKAYSXG-VHKSKYWEYVYEDTMNLIAKLPVIAAT 687
+P HPM+ FS V AL S SKFA AY+ G +K YWEY ED+++++A+ P +AA
Sbjct: 151 ALPRNAHPMTAFSVGVLALQSYSKFAAAYAAGKSNKKTYWEYALEDSLDMLARTPTVAAM 210
Query: 688 IYRNVYRDGKG 720
IY R+ KG
Sbjct: 211 IYN---RETKG 218
>UniRef50_UPI00006CFBEC Cluster: Citrate synthase family protein;
n=1; Tetrahymena thermophila SB210|Rep: Citrate synthase
family protein - Tetrahymena thermophila SB210
Length = 551
Score = 181 bits (440), Expect = 2e-44
Identities = 89/191 (46%), Positives = 123/191 (64%), Gaps = 7/191 (3%)
Frame = +1
Query: 166 PRXQEKIREFRKKHGSTKVGEVTVDMMYGGMRGIKGLVWETSVLDADEGIRFRGLSIPEC 345
P+ Q +++E ++K+G VG+ TV + GGMRG+KGL+ + S D +GI FRG +IP+
Sbjct: 35 PQKQAELKEVKEKYGDKVVGQYTVKQVIGGMRGMKGLMSDLSRCDPYQGIIFRGYTIPQL 94
Query: 346 QQQLPKA------KGGEEPLPEGLFWLLVTGDIPTEAQAKALSKEWAARAELPAHVVTML 507
++ LPKA + +EPLPEG+FWLL+TG +PT AQ AL EW R + V +
Sbjct: 95 KEFLPKADPKAADQANQEPLPEGIFWLLMTGQLPTHAQVDALKHEWQNRGTVNQDCVNFI 154
Query: 508 NNMPGKLHPMSQFSAAVTALNSESKFAKAYSXG-VHKSKYWEYVYEDTMNLIAKLPVIAA 684
N+P LH M+ S A+ L +SKFAK Y G + K YWE YED+M+LIAK+P +AA
Sbjct: 155 LNLPKDLHSMTMLSMALLYLQKDSKFAKLYDEGKISKKDYWEPFYEDSMDLIAKIPRVAA 214
Query: 685 TIYRNVYRDGK 717
IYR+ YRD K
Sbjct: 215 IIYRHKYRDSK 225
>UniRef50_UPI00006CBE2B Cluster: citrate synthase; n=1; Tetrahymena
thermophila SB210|Rep: citrate synthase - Tetrahymena
thermophila SB210
Length = 474
Score = 180 bits (438), Expect = 3e-44
Identities = 89/226 (39%), Positives = 137/226 (60%), Gaps = 9/226 (3%)
Frame = +1
Query: 73 NCRKHVRLRQFYFEV*ALNRRI*KVFSRKRFPRXQEKIREFRKKHGSTKVGEVTVDMMYG 252
NC++ Q++F + K R++ P + E +KK+G +GE+TV+ G
Sbjct: 7 NCKRLYHQNQYFFNP----KADLKTVLREQIPIKIQGFNEMKKKYGDRVMGEITVNQALG 62
Query: 253 GMRGIKGLVWETSVLDADEGIRFRGLSIPECQQQLPKAK--------GGEEPLPEGLFWL 408
GMRGI+ L ++ S +D +G+ FRG SIPE + LPK + ++PLPEGLF+L
Sbjct: 63 GMRGIRALFYDQSTVDPIDGVMFRGYSIPELHELLPKLRKPSAEDFQSDQQPLPEGLFFL 122
Query: 409 LVTGDIPTEAQAKALSKEWAARAELPAHVVTMLNNMPGKLHPMSQFSAAVTALNSESKFA 588
L+TG++P+ Q + + EW R ++ ++ +N + K+HPM+ S A+ SKFA
Sbjct: 123 LLTGELPSYHQVELIRHEWDVRGKVSDELINFINRLDNKMHPMTMLSLAILYEQKTSKFA 182
Query: 589 KAYSXG-VHKSKYWEYVYEDTMNLIAKLPVIAATIYRNVYRDGKGI 723
+ Y+ ++KS YWEY YED+++LIAKLP IAATIYR ++DGK I
Sbjct: 183 QLYNESKLNKSNYWEYTYEDSVDLIAKLPRIAATIYRKKFKDGKPI 228
>UniRef50_A0DZ50 Cluster: Citrate synthase; n=6; Paramecium
tetraurelia|Rep: Citrate synthase - Paramecium
tetraurelia
Length = 459
Score = 180 bits (438), Expect = 3e-44
Identities = 87/209 (41%), Positives = 128/209 (61%), Gaps = 1/209 (0%)
Frame = +1
Query: 94 LRQFYFEV*ALNRRI*KVFSRKRFPRXQEKIREFRKKHGSTKVGEVTVDMMYGGMRGIKG 273
++ FY V + K R+ P Q +R+ RK++G+ +V +VTVD GGMR + G
Sbjct: 9 VQMFYRSVYNNTHGLLKKRMRELVPVKQALLRDVRKRYGAKEVCKVTVDQAIGGMRNVFG 68
Query: 274 LVWETSVLDADEGIRFRGLSIPECQQQLPKAKGGEEPLPEGLFWLLVTGDIPTEAQAKAL 453
L ++ S+LDA GI R +IPE Q+ L KA+ G EPLPE LFWLL TGD P+E + +
Sbjct: 69 LFYDASLLDAKTGITMRDYNIPELQEYLQKAENGHEPLPEALFWLLCTGDFPSEQEFADV 128
Query: 454 SKEWAARAELPAHVVTMLNNMPGKLHPMSQFSAAVTALNSESKFAKAYSXG-VHKSKYWE 630
+EW R +L + + ++P HPM+ S + L +S+F + Y G V K +YWE
Sbjct: 129 QQEWKQRGQLDSETQKFILSLPKAAHPMTMLSQTLLFLQKDSQFQQVYDQGKVSKPQYWE 188
Query: 631 YVYEDTMNLIAKLPVIAATIYRNVYRDGK 717
Y YED M+L+AK+P +AA IYR+ Y++G+
Sbjct: 189 YFYEDAMDLLAKIPRVAALIYRHKYKNGE 217
>UniRef50_Q95TZ4 Cluster: Citrate synthase; n=1; Drosophila
melanogaster|Rep: Citrate synthase - Drosophila
melanogaster (Fruit fly)
Length = 478
Score = 176 bits (428), Expect = 5e-43
Identities = 79/189 (41%), Positives = 126/189 (66%), Gaps = 1/189 (0%)
Frame = +1
Query: 157 KRFPRXQEKIREFRKKHGSTKVGEVTVDMMYGGMRGIKGLVWETSVLDADEGIRFRGLSI 336
K+ P +EK + HG +G+++V+ + GGMRG+ L ETS LD ++GI +RG +
Sbjct: 39 KKIPIEREKFLGIKCLHGKKIIGQISVNSVIGGMRGLPLLFCETSSLDKNKGIYYRGKLL 98
Query: 337 PECQQQLPKAKGG-EEPLPEGLFWLLVTGDIPTEAQAKALSKEWAARAELPAHVVTMLNN 513
+ +LP+ + G +E PEG F+LL +G +PT+ +A+ ++ EW R +P + + M+++
Sbjct: 99 KDVCAKLPRVQEGTQEGTPEGCFFLLTSGSMPTKKEAQEVTNEWLKRGSVPRYCLRMIDS 158
Query: 514 MPGKLHPMSQFSAAVTALNSESKFAKAYSXGVHKSKYWEYVYEDTMNLIAKLPVIAATIY 693
M ++HPM+Q AA LN +S+F +AY+ G ++ YW+Y YED+MNLIA LP +AA IY
Sbjct: 159 MDKRVHPMAQLCAASACLNPQSQFVEAYTKGARRADYWKYSYEDSMNLIAMLPTVAAAIY 218
Query: 694 RNVYRDGKG 720
NV+RDG+G
Sbjct: 219 SNVFRDGEG 227
>UniRef50_Q6JGH9 Cluster: Citrate synthase; n=17;
Desulfuromonadales|Rep: Citrate synthase - Geobacter
metallireducens
Length = 441
Score = 163 bits (395), Expect = 5e-39
Identities = 81/189 (42%), Positives = 114/189 (60%), Gaps = 8/189 (4%)
Frame = +1
Query: 175 QEKIREFR-------KKHGSTKVGEVTVDMMYGGMRGIKGLVWETSVLDADEGIRFRGLS 333
++KI EFR K+ G + +VT+D GG R I+ LV + S LD EGIRFRG +
Sbjct: 8 KQKIEEFRPRTTRLVKEFGKVVIDQVTIDQAIGGARDIRSLVTDISYLDPQEGIRFRGKT 67
Query: 334 IPECQQQLPKAKGGEEPLPEGLFWLLVTGDIPTEAQAKALSKEWAARAELPAHVVTMLNN 513
IPE + LPKA G + P E ++ L+TG++PT+AQ + EW R +P +V ++
Sbjct: 68 IPETFEALPKASGSDYPTVESFWYFLLTGEVPTQAQVDEVVAEWKTRQVVPQYVFDAISA 127
Query: 514 MPGKLHPMSQFSAAVTALNSESKFAKAYSXG-VHKSKYWEYVYEDTMNLIAKLPVIAATI 690
+P + HPM S + AL +SKFA Y+ G +K WEYVYED +L+A++P+IAA I
Sbjct: 128 LPKESHPMVMLSVGILALQKDSKFAGFYNSGKFNKMTAWEYVYEDASDLVARIPIIAAFI 187
Query: 691 YRNVYRDGK 717
Y YR GK
Sbjct: 188 YNLKYRGGK 196
>UniRef50_P43635 Cluster: Citrate synthase 3; n=7;
Saccharomycetales|Rep: Citrate synthase 3 -
Saccharomyces cerevisiae (Baker's yeast)
Length = 486
Score = 155 bits (376), Expect = 1e-36
Identities = 71/186 (38%), Positives = 118/186 (63%), Gaps = 3/186 (1%)
Frame = +1
Query: 166 PRXQEKIREFRKKHGSTKVGEVTVDMMYGGMRGIKGLVWETSVLDADEGIRFRGLSIPEC 345
P+ ++ +++ + +GST VG +T+ + GGMRG + + W+ + LD + GI+F+GL+I EC
Sbjct: 38 PKKRDAVKKLKACYGSTFVGPITISSVLGGMRGNQSMFWQGTSLDPEHGIKFQGLTIEEC 97
Query: 346 QQQLPKAK-GGEEPLPEGLFWLLVTGDIPTEAQAKALSKEWAARA-ELPAHVVTMLNNMP 519
Q +LP G+ LPE + WLL+TG +PT QA + KE A R +LP + +L+++P
Sbjct: 98 QNRLPNTGIDGDNFLPESMLWLLMTGGVPTFQQAASFRKELAIRGRKLPHYTEKVLSSLP 157
Query: 520 GKLHPMSQFSAAVTALNSESKFAKAYSXG-VHKSKYWEYVYEDTMNLIAKLPVIAATIYR 696
+HPM+Q + + ++N S FA Y G + K ++W+ ED++NLIA LP++ IY
Sbjct: 158 KDMHPMTQLAIGLASMNKGSLFATNYQKGLIGKMEFWKDTLEDSLNLIASLPLLTGRIYS 217
Query: 697 NVYRDG 714
N+ +G
Sbjct: 218 NITNEG 223
>UniRef50_UPI00015B4F54 Cluster: PREDICTED: hypothetical protein;
n=1; Nasonia vitripennis|Rep: PREDICTED: hypothetical
protein - Nasonia vitripennis
Length = 479
Score = 146 bits (355), Expect = 4e-34
Identities = 72/191 (37%), Positives = 115/191 (60%), Gaps = 13/191 (6%)
Frame = +1
Query: 157 KRFPRXQEKIREFRKKHGSTKVGEVTVDMMYGGMRGIKGLVWETSVLDADEGIRFRGLSI 336
++ P + +R+FR++HG V ++TV+ +Y G+ G+ L+ ETS +D+ GI++RGLSI
Sbjct: 24 EKIPLHHDLLRKFRQQHGLDVVSQITVNDIYRGLDGVTALIRETSEIDSQCGIKYRGLSI 83
Query: 337 PECQQQLPKAKGGEEPLPEGLFWLLVTGDIPTEAQAKALSKEWAAR-------------A 477
PE Q LP+ G+ P PE +FWLL+TGD+PT Q +AL+ +W R
Sbjct: 84 PELYQLLPRR--GKSPSPEAVFWLLLTGDVPTHEQTEALTADWTERRERRKDWWWSGSSG 141
Query: 478 ELPAHVVTMLNNMPGKLHPMSQFSAAVTALNSESKFAKAYSXGVHKSKYWEYVYEDTMNL 657
E+ V +L +P + P+ + + A+TAL+++ + KA G YWE++YED+M L
Sbjct: 142 EIGGVVGGVLRALPKNVAPVGRLAIALTALDADKHYRKAVESGAMSYTYWEHIYEDSMEL 201
Query: 658 IAKLPVIAATI 690
+A LP I A +
Sbjct: 202 LASLPAIVALV 212
>UniRef50_Q4N4H4 Cluster: Citrate synthase, putative; n=3;
Piroplasmida|Rep: Citrate synthase, putative - Theileria
parva
Length = 676
Score = 139 bits (337), Expect = 6e-32
Identities = 69/180 (38%), Positives = 103/180 (57%), Gaps = 1/180 (0%)
Frame = +1
Query: 175 QEKIREFRKKHGSTKVGEVTVDMMYGGMRGIKGLVWETSVLDADEGIRFRGLSIPECQQQ 354
+EK+ E K+ ++GEVT+ M++ G++ + +V ETS LD GIRFRGL++ E
Sbjct: 251 REKVAELHNKYADCRLGEVTLSMLFSGLKDVPAMVTETSELDPFNGIRFRGLTVDEMLTA 310
Query: 355 LPKAKGGEEPLPEGLFWLLVTGDIPTEAQAKALSKEWAARAELPAHVVTMLNNMPGKLHP 534
LP K + P E + W L+TG++P+ LS E R+ +P HV +++ P HP
Sbjct: 311 LP-GKNPDCPYTESVLWFLLTGEVPSPVDVDDLSYELYRRSTVPEHVYKVIDGFPTDAHP 369
Query: 535 MSQFSAAVTALNSESKFAKAY-SXGVHKSKYWEYVYEDTMNLIAKLPVIAATIYRNVYRD 711
M+Q+ AV+AL +ES F +AY HK W+ ED +NL AK V+ IYR + D
Sbjct: 370 MTQYITAVSALQTESVFREAYFDKTYHKDTCWKLALEDCLNLFAKNVVLVGYIYRRSFID 429
>UniRef50_UPI0000DB6B6F Cluster: PREDICTED: similar to citrate
synthase; n=1; Apis mellifera|Rep: PREDICTED: similar to
citrate synthase - Apis mellifera
Length = 795
Score = 134 bits (324), Expect = 2e-30
Identities = 69/196 (35%), Positives = 110/196 (56%), Gaps = 9/196 (4%)
Frame = +1
Query: 157 KRFPRXQEKIREFRKKHGSTKVGEVTVDMMYGGMRGIKGLVWETSVLDADEGIRFRGLSI 336
++ P + +R FR++HGS+ + +VTV+ +Y G+ G+ +V ETS D+ GI++RGL+I
Sbjct: 42 EKIPIHYDLLRNFRQQHGSSVISQVTVENIYQGLNGVNTIVRETSETDSKYGIKYRGLTI 101
Query: 337 PECQQQLPKAKGGEEPLPEGLFWLLVTGDIPTEAQAKALSKEWAARAELPAH-------- 492
PE LP+ G+ P E +FWLL+TGD+PT+ Q +L +W+ R +
Sbjct: 102 PEVITLLPRE--GKSPSAEAVFWLLLTGDVPTKEQTASLIADWSIRRQKKKDWWSGPGGG 159
Query: 493 -VVTMLNNMPGKLHPMSQFSAAVTALNSESKFAKAYSXGVHKSKYWEYVYEDTMNLIAKL 669
V ++L N+P P+ + S A+T S +A G +WEY YED+M L+A L
Sbjct: 160 IVGSVLQNLPKTTTPLGKLSIALTVFESGKYIQEALKNGALSYTHWEYTYEDSMELLATL 219
Query: 670 PVIAATIYRNVYRDGK 717
P I I + ++ K
Sbjct: 220 PAIVGLIAKGELKNLK 235
>UniRef50_A4ZVV6 Cluster: Mitochondrial citrate synthase 1; n=1;
Toxoplasma gondii|Rep: Mitochondrial citrate synthase 1
- Toxoplasma gondii
Length = 554
Score = 132 bits (320), Expect = 6e-30
Identities = 74/195 (37%), Positives = 110/195 (56%), Gaps = 12/195 (6%)
Frame = +1
Query: 175 QEKIREFRKKHGSTKVGEVTVDMMYGGMRGIKGLVWETSVLDADEGIRFRGLSIPECQQQ 354
+E ++ RK+HG+ + E T+ + GGMRG+ ++ ETS L A++GI +RGL+I EC +
Sbjct: 126 RELLKTLRKEHGTVVISEATLSTVCGGMRGLTAILTETSTLHAEKGILYRGLTINECLAK 185
Query: 355 LPKAKGGEEPLPEGLFWLLVTGDIPTEAQAKALSKEWAARA-----------ELPAHVVT 501
LP+ E P EGL W L+TG IPT + + LS A + +P HV
Sbjct: 186 LPRMHKEEYPAVEGLIWFLMTGSIPTVNEVELLSNALYALSLSSASSSPSAPFIPPHVGK 245
Query: 502 MLNNMPGKLHPMSQFSAAVTALNSESKFAKAY-SXGVHKSKYWEYVYEDTMNLIAKLPVI 678
+L+ +P HPM+Q A AL S+ A+AY V + W+ D ++LIAK V+
Sbjct: 246 VLDAVPPSTHPMTQLVMAAAALQPTSELAQAYRHKTVSRHDLWKPALADALSLIAKNAVM 305
Query: 679 AATIYRNVYRDGKGI 723
AA I+R +RDG+ I
Sbjct: 306 AARIFRRSFRDGQEI 320
>UniRef50_A5KE63 Cluster: Citrate synthase, mitochondrial, putative;
n=13; Plasmodium|Rep: Citrate synthase, mitochondrial,
putative - Plasmodium vivax
Length = 569
Score = 117 bits (282), Expect = 3e-25
Identities = 60/183 (32%), Positives = 105/183 (57%), Gaps = 2/183 (1%)
Frame = +1
Query: 169 RXQEKIREFRKKHGSTKVGEVTVDMMYGGMRGIKGLVWETSVLDADEGIRFRGLSIPECQ 348
+ +EK++ + +T + T + + GG+R L+ +TS+L+ +GI FRG ++ +
Sbjct: 133 KTREKLKAIIHTYPNTPISICTPNNVIGGLRNTITLITDTSILEKRKGILFRGRTVDKIL 192
Query: 349 QQLPK-AKGGEEPLPEGLFWLLVTGDIPTEAQAKALSKEWAARAE-LPAHVVTMLNNMPG 522
+ PK + E P+ E + W L+T +IP K S+E RA+ +P+ V ++++P
Sbjct: 193 KDFPKWDENCEYPMAEAMLWYLLTKEIPAADDLKLFSRELYCRAKKMPSFVFEFIDSIPT 252
Query: 523 KLHPMSQFSAAVTALNSESKFAKAYSXGVHKSKYWEYVYEDTMNLIAKLPVIAATIYRNV 702
HPMSQ + V+ L S S F YS G+ K YW+Y+ ED ++LIA++ V+ A I++
Sbjct: 253 FTHPMSQLVSTVSFLESLSLFKIKYSEGILKKDYWKYILEDAVSLIAQIQVVCAYIFKRS 312
Query: 703 YRD 711
+ D
Sbjct: 313 FID 315
>UniRef50_UPI0000D9A0A8 Cluster: PREDICTED: similar to citrate
synthase precursor, isoform a; n=1; Macaca mulatta|Rep:
PREDICTED: similar to citrate synthase precursor,
isoform a - Macaca mulatta
Length = 112
Score = 81.0 bits (191), Expect = 3e-14
Identities = 38/52 (73%), Positives = 42/52 (80%)
Frame = +1
Query: 244 MYGGMRGIKGLVWETSVLDADEGIRFRGLSIPECQQQLPKAKGGEEPLPEGL 399
MYG MRGIKGLV++TSVLD EG F+G SIPE Q+ LPKAKGGE PLP GL
Sbjct: 1 MYGDMRGIKGLVYKTSVLDPHEGFCFQGFSIPEYQKLLPKAKGGEGPLPRGL 52
>UniRef50_Q6MAA4 Cluster: Putative citrate (Si)-synthase; n=1;
Candidatus Protochlamydia amoebophila UWE25|Rep:
Putative citrate (Si)-synthase - Protochlamydia
amoebophila (strain UWE25)
Length = 386
Score = 48.4 bits (110), Expect = 2e-04
Identities = 42/155 (27%), Positives = 69/155 (44%)
Frame = +1
Query: 226 EVTVDMMYGGMRGIKGLVWETSVLDADEGIRFRGLSIPECQQQLPKAKGGEEPLPEGLFW 405
E+T + + G+RG TS +D +G+ + G + E Q P E + +
Sbjct: 7 EITKESLETGLRGYPVGYCTTSSVDPVKGLFYAGHPVSEIDQWEP----------EQVIY 56
Query: 406 LLVTGDIPTEAQAKALSKEWAARAELPAHVVTMLNNMPGKLHPMSQFSAAVTALNSESKF 585
LL G + + S++ RA ++ + +P +HPM FS A+
Sbjct: 57 LLYHGYVGKPEEVSRFSQDLLIRANCSTALIESIEKLPRNIHPMKLFSIALL-------L 109
Query: 586 AKAYSXGVHKSKYWEYVYEDTMNLIAKLPVIAATI 690
A + K+ Y +ED +NLIAK+P IAAT+
Sbjct: 110 ASGFEG---KNDY----HEDYLNLIAKVPEIAATV 137
>UniRef50_Q8F887 Cluster: Citrate synthase; n=4; Leptospira|Rep:
Citrate synthase - Leptospira interrogans
Length = 426
Score = 48.0 bits (109), Expect = 2e-04
Identities = 28/100 (28%), Positives = 52/100 (52%)
Frame = +1
Query: 403 WLLVTGDIPTEAQAKALSKEWAARAELPAHVVTMLNNMPGKLHPMSQFSAAVTALNSESK 582
+LL+ G +PTE Q K S + + + + ++ + + PGK HP++ S VT+L+ S
Sbjct: 87 YLLIYGKLPTEQQLKDFSLKLSKHSLIHEDMINLFDGFPGKGHPLAVLSVMVTSLS--SY 144
Query: 583 FAKAYSXGVHKSKYWEYVYEDTMNLIAKLPVIAATIYRNV 702
+ + Y + K + + L+AK+ IAA Y+ +
Sbjct: 145 YPEEYEESLDKG------IDHSARLLAKIRTIAAFSYKKI 178
>UniRef50_Q8ZWP2 Cluster: Citrate synthase; n=7;
Thermoproteaceae|Rep: Citrate synthase - Pyrobaculum
aerophilum
Length = 409
Score = 47.6 bits (108), Expect = 3e-04
Identities = 44/148 (29%), Positives = 69/148 (46%), Gaps = 7/148 (4%)
Frame = +1
Query: 274 LVWETSV--LDADEGIR-FRGLSIPECQQQLPKAKGGEEPLPEGLFWLLVTGDIPTEAQA 444
L+ TS+ +D ++GI +RG I E L + EE + +L++ G +PT+ +
Sbjct: 30 LIKSTSISDIDGEKGILWYRGYRIEE----LARLSTYEE-----VSYLILYGRLPTKREL 80
Query: 445 KALSKEWAARAELPAHVVTMLNNMPGKLHPMSQFSAAVTALNS----ESKFAKAYSXGVH 612
+ EL V ++ N+ K HPM AAV A + K +A S G +
Sbjct: 81 EDYINRMKKYRELHPATVEVIRNL-AKAHPMFALEAAVAAEGAYDEDNQKLIEALSVGRY 139
Query: 613 KSKYWEYVYEDTMNLIAKLPVIAATIYR 696
K++ E Y L+AK+P I A YR
Sbjct: 140 KAEEKELAYRIAEKLVAKMPTIVAYHYR 167
>UniRef50_Q9LXS7 Cluster: Citrate synthase 1, peroxisomal precursor;
n=11; cellular organisms|Rep: Citrate synthase 1,
peroxisomal precursor - Arabidopsis thaliana (Mouse-ear
cress)
Length = 480
Score = 46.8 bits (106), Expect = 5e-04
Identities = 36/138 (26%), Positives = 67/138 (48%), Gaps = 3/138 (2%)
Frame = +1
Query: 289 SVLDADEGI-RFRGLSIPECQQQLPKAKGGEEPLPEGLFWLLVTGDIPTEAQAKALSKEW 465
S +D DEGI R+RG + E ++ + + +LL+ G++P++ Q
Sbjct: 107 SYIDGDEGILRYRGYPVEELAEKSTYTE---------VTYLLIYGNLPSQRQLADWEFAI 157
Query: 466 AARAELPAHVVTMLNNMPGKLHPMSQFSAAVTALNSESKFA--KAYSXGVHKSKYWEYVY 639
+ + +P V+ M+ +MP +HP+ A++AL+ A GV+KSK +
Sbjct: 158 SQNSAVPQGVLDMIQSMPNDVHPVGALVTAMSALSIFYPDANPSLMGLGVYKSK--QVRD 215
Query: 640 EDTMNLIAKLPVIAATIY 693
+ + ++ + P IAA Y
Sbjct: 216 KQIVRVLGQAPTIAAAAY 233
>UniRef50_Q550V8 Cluster: Citrate synthase; n=3; Dictyostelium
discoideum|Rep: Citrate synthase - Dictyostelium
discoideum AX4
Length = 512
Score = 45.2 bits (102), Expect = 0.002
Identities = 33/140 (23%), Positives = 68/140 (48%), Gaps = 1/140 (0%)
Frame = +1
Query: 283 ETSVLDADEGI-RFRGLSIPECQQQLPKAKGGEEPLPEGLFWLLVTGDIPTEAQAKALSK 459
+ + +D D GI +RG I +QL + E + +LL+ GD+P++ Q+ +
Sbjct: 72 QITYIDGDRGILEYRGYPI----EQLAEKSSFLE-----VSYLLIYGDLPSKEQSNLWNT 122
Query: 460 EWAARAELPAHVVTMLNNMPGKLHPMSQFSAAVTALNSESKFAKAYSXGVHKSKYWEYVY 639
+ + ++++M+ + HPM ++++A+++ A GV K + +
Sbjct: 123 KIMNHTFIHENLISMMKSFRYDAHPMGMLISSLSAMSTFYPEANPALAGVDIYKNKQLMN 182
Query: 640 EDTMNLIAKLPVIAATIYRN 699
+ ++ KLP IAA YR+
Sbjct: 183 KQIFRILGKLPTIAACAYRH 202
>UniRef50_O28929 Cluster: Citrate synthase; n=2; cellular
organisms|Rep: Citrate synthase - Archaeoglobus fulgidus
Length = 372
Score = 45.2 bits (102), Expect = 0.002
Identities = 32/111 (28%), Positives = 51/111 (45%)
Frame = +1
Query: 391 EGLFWLLVTGDIPTEAQAKALSKEWAARAELPAHVVTMLNNMPGKLHPMSQFSAAVTALN 570
E + +LL+ G++P + + + E A R ELP ++ +L ++P HPM A + L
Sbjct: 44 EEVAYLLLYGELPKKYELQDFKIELAERRELPPQIIGLLTHLPPYTHPMVVLRTATSYLG 103
Query: 571 SESKFAKAYSXGVHKSKYWEYVYEDTMNLIAKLPVIAATIYRNVYRDGKGI 723
S K + E + +LIAK P I A +R R G+ I
Sbjct: 104 SLDKKIAVRTR--------EETFNKAKDLIAKFPTIVAYYHR--IRTGRNI 144
>UniRef50_Q8RV72 Cluster: Putative citrate synthetase; n=1;
Arabidopsis thaliana|Rep: Putative citrate synthetase -
Arabidopsis thaliana (Mouse-ear cress)
Length = 83
Score = 44.0 bits (99), Expect = 0.004
Identities = 17/34 (50%), Positives = 25/34 (73%)
Frame = +1
Query: 175 QEKIREFRKKHGSTKVGEVTVDMMYGGMRGIKGL 276
Q++ ++ + KHG VG +TVDM+ GGMRG+ GL
Sbjct: 43 QDRSKKLKLKHGKVPVGNITVDMVLGGMRGMTGL 76
>UniRef50_Q9LXS6 Cluster: Citrate synthase 2, peroxisomal precursor;
n=10; cellular organisms|Rep: Citrate synthase 2,
peroxisomal precursor - Arabidopsis thaliana (Mouse-ear
cress)
Length = 514
Score = 44.0 bits (99), Expect = 0.004
Identities = 36/136 (26%), Positives = 66/136 (48%), Gaps = 3/136 (2%)
Frame = +1
Query: 295 LDADEGI-RFRGLSIPECQQQLPKAKGGEEPLPEGLFWLLVTGDIPTEAQAKALSKEWAA 471
+D DEGI R+RG I E + + + +LL+ G++P+++Q +
Sbjct: 112 IDGDEGILRYRGYPIEELAESSTFIE---------VAYLLMYGNLPSQSQLADWEFTVSQ 162
Query: 472 RAELPAHVVTMLNNMPGKLHPMSQFSAAVTALNSESKFAKAYSXG--VHKSKYWEYVYED 645
+ +P V+ ++ +MP HPM +A++AL+ A G ++KSK + +
Sbjct: 163 HSAVPQGVLDIIQSMPHDAHPMGVLVSAMSALSIFHPDANPALSGQDIYKSK--QVRDKQ 220
Query: 646 TMNLIAKLPVIAATIY 693
+ ++ K P IAA Y
Sbjct: 221 IVRILGKAPTIAAAAY 236
>UniRef50_P56062 Cluster: Citrate synthase; n=43;
Epsilonproteobacteria|Rep: Citrate synthase -
Helicobacter pylori (Campylobacter pylori)
Length = 426
Score = 43.2 bits (97), Expect = 0.007
Identities = 31/101 (30%), Positives = 53/101 (52%), Gaps = 3/101 (2%)
Frame = +1
Query: 406 LLVTGDIPTEAQAKALSKEWAARAELPAH--VVTMLNNMPGKLHPMSQFSAAVTALNSES 579
LL+TG++P Q ++L E R H ++ M + P HPM++ S+ V+ L++
Sbjct: 88 LLLTGELPKN-QDESLEFELELRHRSFVHESLLNMFSAFPSNAHPMAKLSSGVSILST-- 144
Query: 580 KFAKAYSXGVHKSKYWEYVYED-TMNLIAKLPVIAATIYRN 699
YS H++ + E Y+ ++AK+P +AA YRN
Sbjct: 145 ----LYS--THQNMHTEEDYQTMARRIVAKIPTLAAICYRN 179
>UniRef50_P45858 Cluster: Citrate synthase 3; n=19; Bacillaceae|Rep:
Citrate synthase 3 - Bacillus subtilis
Length = 372
Score = 40.7 bits (91), Expect = 0.036
Identities = 25/100 (25%), Positives = 47/100 (47%)
Frame = +1
Query: 397 LFWLLVTGDIPTEAQAKALSKEWAARAELPAHVVTMLNNMPGKLHPMSQFSAAVTALNSE 576
L LL+ G +P E++ + L ++ + + LPA + +L +P HPM ++AL
Sbjct: 50 LVHLLLEGRLPEESEMETLERKINSASSLPADHLRLLELLPEDTHPMDGLRTGLSALAGY 109
Query: 577 SKFAKAYSXGVHKSKYWEYVYEDTMNLIAKLPVIAATIYR 696
+ S +K + ++ L+ K+P + A YR
Sbjct: 110 DRQIDDRSPSANKERAYQ--------LLGKMPALTAASYR 141
>UniRef50_Q7W5Q6 Cluster: 2-methylcitrate synthase; n=122;
Bacteria|Rep: 2-methylcitrate synthase - Bordetella
parapertussis
Length = 400
Score = 40.3 bits (90), Expect = 0.047
Identities = 21/59 (35%), Positives = 31/59 (52%)
Frame = +1
Query: 391 EGLFWLLVTGDIPTEAQAKALSKEWAARAELPAHVVTMLNNMPGKLHPMSQFSAAVTAL 567
E + LLV G +P +A+ KA ++ A LPA + +L +P HPM AV+ L
Sbjct: 70 EEIAHLLVHGKLPNKAELKAYKEKLRALRGLPAQLQNVLECLPASSHPMDVMRTAVSVL 128
>UniRef50_A6ERK5 Cluster: Citrate synthase; n=1; unidentified
eubacterium SCB49|Rep: Citrate synthase - unidentified
eubacterium SCB49
Length = 451
Score = 40.3 bits (90), Expect = 0.047
Identities = 40/159 (25%), Positives = 71/159 (44%), Gaps = 1/159 (0%)
Frame = +1
Query: 223 GEVTVDMMYGGMRGIKGLVWETSVLDADEGI-RFRGLSIPECQQQLPKAKGGEEPLPEGL 399
G T+D Y + + + L+ +EGI R+RG SI E + KA E +
Sbjct: 62 GVTTIDPGYKNTGACESAI---TFLNGEEGILRYRGYSIEELAE---KASFLE------V 109
Query: 400 FWLLVTGDIPTEAQAKALSKEWAARAELPAHVVTMLNNMPGKLHPMSQFSAAVTALNSES 579
+LL+ G++PT+AQ + + + + +L+ P HPM S+ +AL
Sbjct: 110 AYLLIFGELPTQAQLDNFHSDIKEESVVDDDLKKILDAFPKSAHPMGVLSSLTSALT--- 166
Query: 580 KFAKAYSXGVHKSKYWEYVYEDTMNLIAKLPVIAATIYR 696
A++ + E +Y+ + ++ K PV+ A R
Sbjct: 167 ----AFNPSSVNVESDEDMYKAIVKILGKFPVLVAWTMR 201
>UniRef50_Q56063 Cluster: 2-methylcitrate synthase; n=14;
Enterobacteriaceae|Rep: 2-methylcitrate synthase -
Salmonella typhimurium
Length = 389
Score = 39.5 bits (88), Expect = 0.082
Identities = 20/54 (37%), Positives = 28/54 (51%)
Frame = +1
Query: 406 LLVTGDIPTEAQAKALSKEWAARAELPAHVVTMLNNMPGKLHPMSQFSAAVTAL 567
LL+ G +PT + A + A LPA+V T+L +P HPM V+AL
Sbjct: 64 LLIHGKLPTRDELNAYKSKLKALRGLPANVRTVLEALPAASHPMDVMRTGVSAL 117
>UniRef50_Q8NSL1 Cluster: 2-methylcitrate synthase 2; n=29;
Bacteria|Rep: 2-methylcitrate synthase 2 -
Corynebacterium glutamicum (Brevibacterium flavum)
Length = 383
Score = 38.7 bits (86), Expect = 0.14
Identities = 19/76 (25%), Positives = 42/76 (55%), Gaps = 1/76 (1%)
Frame = +1
Query: 391 EGLFWLLVTGDIPTEAQAKALSKEWAARAELPAHVVTMLNNMPGKLHPMSQFSAAVTALN 570
E +F+LL G++PT Q ++ + L A ++++++++P + HPM AV+ +
Sbjct: 50 EEVFYLLWHGELPTAQQLAEFNERGRSYRSLDAGLISLIHSLPKEAHPMDVMRTAVSYMG 109
Query: 571 S-ESKFAKAYSXGVHK 615
+ +S++ S + K
Sbjct: 110 TKDSEYFTTDSEHIRK 125
>UniRef50_A7C184 Cluster: Citrate synthase; n=1; Beggiatoa sp.
PS|Rep: Citrate synthase - Beggiatoa sp. PS
Length = 293
Score = 37.9 bits (84), Expect = 0.25
Identities = 27/94 (28%), Positives = 43/94 (45%)
Frame = +1
Query: 403 WLLVTGDIPTEAQAKALSKEWAARAELPAHVVTMLNNMPGKLHPMSQFSAAVTALNSESK 582
+LL+ G++PT+ Q + + L ++ N HPM+ V AL+S
Sbjct: 90 YLLLYGELPTQVQLENFHESIHQHTMLNEGLLRFYNGFRHNAHPMAILVGVVGALSSYYY 149
Query: 583 FAKAYSXGVHKSKYWEYVYEDTMNLIAKLPVIAA 684
A + VH++K + LIAK+P IAA
Sbjct: 150 DAMDINNPVHRNK-------SAIRLIAKMPTIAA 176
>UniRef50_A6T3T1 Cluster: 2-methylcitrate synthase; n=60;
Bacteria|Rep: 2-methylcitrate synthase -
Janthinobacterium sp. (strain Marseille) (Minibacterium
massiliensis)
Length = 387
Score = 37.9 bits (84), Expect = 0.25
Identities = 22/59 (37%), Positives = 29/59 (49%)
Frame = +1
Query: 391 EGLFWLLVTGDIPTEAQAKALSKEWAARAELPAHVVTMLNNMPGKLHPMSQFSAAVTAL 567
E + LLV G +PT A+ KA + LPA+V L +P HPM V+AL
Sbjct: 57 EEIAHLLVHGKLPTAAELKAYKIKLKELRGLPANVKAALEWLPAASHPMDVMRTGVSAL 115
>UniRef50_A4KFK1 Cluster: Citrate synthase I gltA2; n=1;
Mycobacterium tuberculosis str. Haarlem|Rep: Citrate
synthase I gltA2 - Mycobacterium tuberculosis str.
Haarlem
Length = 410
Score = 37.9 bits (84), Expect = 0.25
Identities = 39/161 (24%), Positives = 65/161 (40%), Gaps = 1/161 (0%)
Frame = +1
Query: 217 KVGEVTVDMMYGGMRGIKGLVWETSVLDADEGI-RFRGLSIPECQQQLPKAKGGEEPLPE 393
K G T D+ + K + + +D D GI R+RG I + ++ +
Sbjct: 113 KTGHTTFDVGFANTAAAKSSI---TYIDGDAGILRYRGYPIDQLAEKSTFIE-------- 161
Query: 394 GLFWLLVTGDIPTEAQAKALSKEWAARAELPAHVVTMLNNMPGKLHPMSQFSAAVTALNS 573
+ +LL+ G++P Q + L + + P HPM S+ V AL++
Sbjct: 162 -VCYLLIYGELPDTDQLAQFTGRIQRHTMLHEDLKRFFDGFPRNAHPMPVLSSVVNALSA 220
Query: 574 ESKFAKAYSXGVHKSKYWEYVYEDTMNLIAKLPVIAATIYR 696
Y + + V T+ L+AKLP IAA Y+
Sbjct: 221 Y------YQDALDPMDNGQ-VELSTIRLLAKLPTIAAYAYK 254
>UniRef50_Q59977 Cluster: Citrate synthase; n=37; Bacteria|Rep:
Citrate synthase - Synechocystis sp. (strain PCC 6803)
Length = 397
Score = 37.9 bits (84), Expect = 0.25
Identities = 28/106 (26%), Positives = 46/106 (43%), Gaps = 1/106 (0%)
Frame = +1
Query: 253 GMRGIKGLVWETSVLDADEGI-RFRGLSIPECQQQLPKAKGGEEPLPEGLFWLLVTGDIP 429
G+ G+ S +D +GI +RG+ I E L K+ E + +LL+ G +P
Sbjct: 14 GLAGVPAAKSRVSHVDGTDGILEYRGIRIEE----LAKSSSFIE-----VAYLLIWGKLP 64
Query: 430 TEAQAKALSKEWAARAELPAHVVTMLNNMPGKLHPMSQFSAAVTAL 567
T+A+ + E + H+ M+ P HPM + AL
Sbjct: 65 TQAEIEEFEYEIRTHRRIKYHIRDMMKCFPETGHPMDALQTSAAAL 110
>UniRef50_Q10530 Cluster: Citrate synthase 1; n=288; cellular
organisms|Rep: Citrate synthase 1 - Mycobacterium
tuberculosis
Length = 431
Score = 37.9 bits (84), Expect = 0.25
Identities = 39/161 (24%), Positives = 65/161 (40%), Gaps = 1/161 (0%)
Frame = +1
Query: 217 KVGEVTVDMMYGGMRGIKGLVWETSVLDADEGI-RFRGLSIPECQQQLPKAKGGEEPLPE 393
K G T D+ + K + + +D D GI R+RG I + ++ +
Sbjct: 39 KTGHTTFDVGFANTAAAKSSI---TYIDGDAGILRYRGYPIDQLAEKSTFIE-------- 87
Query: 394 GLFWLLVTGDIPTEAQAKALSKEWAARAELPAHVVTMLNNMPGKLHPMSQFSAAVTALNS 573
+ +LL+ G++P Q + L + + P HPM S+ V AL++
Sbjct: 88 -VCYLLIYGELPDTDQLAQFTGRIQRHTMLHEDLKRFFDGFPRNAHPMPVLSSVVNALSA 146
Query: 574 ESKFAKAYSXGVHKSKYWEYVYEDTMNLIAKLPVIAATIYR 696
Y + + V T+ L+AKLP IAA Y+
Sbjct: 147 Y------YQDALDPMDNGQ-VELSTIRLLAKLPTIAAYAYK 180
>UniRef50_A6CE34 Cluster: Citrate synthase; n=1; Planctomyces maris
DSM 8797|Rep: Citrate synthase - Planctomyces maris DSM
8797
Length = 382
Score = 37.5 bits (83), Expect = 0.33
Identities = 26/102 (25%), Positives = 47/102 (46%)
Frame = +1
Query: 391 EGLFWLLVTGDIPTEAQAKALSKEWAARAELPAHVVTMLNNMPGKLHPMSQFSAAVTALN 570
E + +LL+ G++PT Q A E +P ++ L +P PM+ L
Sbjct: 54 EDVSFLLLNGELPTATQLAAYQAELKQYRSIPPELIDALKKLPVSAPPMA-------LLR 106
Query: 571 SESKFAKAYSXGVHKSKYWEYVYEDTMNLIAKLPVIAATIYR 696
S + A Y + + +E + ++ LI+++P I A I+R
Sbjct: 107 SITSLAGVYDPNA-EIETFENRLQISIKLISQIPTIVAAIHR 147
>UniRef50_Q19T76 Cluster: GltA; n=1; Anaplasma phagocytophilum|Rep:
GltA - Anaplasma phagocytophilum (Ehrlichia
phagocytophila)
Length = 116
Score = 36.7 bits (81), Expect = 0.58
Identities = 25/101 (24%), Positives = 50/101 (49%)
Frame = +1
Query: 397 LFWLLVTGDIPTEAQAKALSKEWAARAELPAHVVTMLNNMPGKLHPMSQFSAAVTALNSE 576
+ +LL+ G +P+E++ + ++ +A ++P V+ ++ + P HPM+ A+ +AL ++
Sbjct: 14 IVYLLLKGTLPSESEYEEFTRILSAEYDVPKLVMDVIRSFPRDSHPMAVLIASFSALAAQ 73
Query: 577 SKFAKAYSXGVHKSKYWEYVYEDTMNLIAKLPVIAATIYRN 699
S + IAK+P I A IYR+
Sbjct: 74 YHLCNIDS------------LTGALVAIAKVPGIVACIYRH 102
>UniRef50_Q7NZ52 Cluster: Citrate (Si)-synthase; n=4; Bacteria|Rep:
Citrate (Si)-synthase - Chromobacterium violaceum
Length = 435
Score = 36.3 bits (80), Expect = 0.77
Identities = 28/98 (28%), Positives = 42/98 (42%)
Frame = +1
Query: 403 WLLVTGDIPTEAQAKALSKEWAARAELPAHVVTMLNNMPGKLHPMSQFSAAVTALNSESK 582
+LL+ G++PT AQ K + L ++++ HPM+ V AL++
Sbjct: 96 YLLLNGELPTAAQRKEFERGVMRHNMLHDQLMSLFKGFRRDAHPMAVMVGVVGALSAFYH 155
Query: 583 FAKAYSXGVHKSKYWEYVYEDTMNLIAKLPVIAATIYR 696
+ S H+ LIAKLP IAA YR
Sbjct: 156 DSLDISNPEHRR-------ISAHRLIAKLPTIAAQAYR 186
>UniRef50_Q2JTT9 Cluster: 2-methylcitrate synthase/citrate synthase
II; n=5; Bacteria|Rep: 2-methylcitrate synthase/citrate
synthase II - Synechococcus sp. (strain JA-3-3Ab)
(Cyanobacteria bacteriumYellowstone A-Prime)
Length = 378
Score = 35.1 bits (77), Expect = 1.8
Identities = 32/149 (21%), Positives = 58/149 (38%), Gaps = 1/149 (0%)
Frame = +1
Query: 253 GMRGIKGLVWETSVLDADEGI-RFRGLSIPECQQQLPKAKGGEEPLPEGLFWLLVTGDIP 429
G+ G+ S +D GI +RG+ I E Q + +LL+ G +P
Sbjct: 9 GLEGVPATRSNISFVDGQAGILEYRGIPIEELTAQSTFLETA---------YLLIFGKLP 59
Query: 430 TEAQAKALSKEWAARAELPAHVVTMLNNMPGKLHPMSQFSAAVTALNSESKFAKAYSXGV 609
T+A+ + + + + M+ + P HPM V +L +A
Sbjct: 60 TQAELDNFDQAVRSHRRVKYRIRDMIKSFPESGHPMDALQTCVASLGMFYPVREADP--- 116
Query: 610 HKSKYWEYVYEDTMNLIAKLPVIAATIYR 696
+YV+ L++KLP + A ++
Sbjct: 117 ------DYVFGTVTRLLSKLPTMVAMFHQ 139
>UniRef50_Q86JM6 Cluster: Similar to Homo sapiens (Human). NPD010;
n=2; Dictyostelium discoideum|Rep: Similar to Homo
sapiens (Human). NPD010 - Dictyostelium discoideum
(Slime mold)
Length = 602
Score = 34.7 bits (76), Expect = 2.3
Identities = 20/56 (35%), Positives = 28/56 (50%)
Frame = +2
Query: 542 SSRLPSPHSTVNLNSLKPTQXACTNPSIGSTCTKTQ*TLSRNCP*SPPLSIATCTA 709
SS PSP + N+N T TN + +T T T T S+ + P++ AT TA
Sbjct: 135 SSPSPSPSANANINVASSTGGGATNATTTTTTTTTTTTPSQPTTTTTPITTATTTA 190
>UniRef50_Q9WYC6 Cluster: Citrate synthase; n=2; Thermotoga|Rep:
Citrate synthase - Thermotoga maritima
Length = 367
Score = 34.3 bits (75), Expect = 3.1
Identities = 27/100 (27%), Positives = 50/100 (50%), Gaps = 3/100 (3%)
Frame = +1
Query: 241 MMYGGMRGIKGLVWETSV--LDADEG-IRFRGLSIPECQQQLPKAKGGEEPLPEGLFWLL 411
M+ G+ G+K + E+S+ LD G + +RG+ + E E+ E + L
Sbjct: 1 MIQKGLEGVK--ICESSICYLDGINGRLYYRGIPVEEL---------AEKSTFEETAYFL 49
Query: 412 VTGDIPTEAQAKALSKEWAARAELPAHVVTMLNNMPGKLH 531
G +PT+++ + ++ A ELPA + +L ++P LH
Sbjct: 50 WYGKLPTKSELEEFKRKMADYRELPAEALGILYHLPKNLH 89
>UniRef50_Q9RWB2 Cluster: Citrate synthase; n=7; Deinococci|Rep:
Citrate synthase - Deinococcus radiodurans
Length = 377
Score = 34.3 bits (75), Expect = 3.1
Identities = 19/71 (26%), Positives = 32/71 (45%)
Frame = +1
Query: 355 LPKAKGGEEPLPEGLFWLLVTGDIPTEAQAKALSKEWAARAELPAHVVTMLNNMPGKLHP 534
+P + E+ E L L+ +PT + E A +P +V ++ +MP +HP
Sbjct: 33 IPIQEWAEKSTFEELSLALLDAKLPTAEELAKFDAELKANRAIPDQLVGIIRDMPKGVHP 92
Query: 535 MSQFSAAVTAL 567
M AV+ L
Sbjct: 93 MQALRTAVSYL 103
>UniRef50_A0RVR8 Cluster: Citrate synthase; n=4; cellular
organisms|Rep: Citrate synthase - Cenarchaeum symbiosum
Length = 465
Score = 33.9 bits (74), Expect = 4.1
Identities = 40/158 (25%), Positives = 64/158 (40%), Gaps = 1/158 (0%)
Frame = +1
Query: 226 EVTVDMMYGGMRGIKGLVWETSVLDADEG-IRFRGLSIPECQQQLPKAKGGEEPLPEGLF 402
E ++D G+RGI S +D +G + +RG I + L EE +
Sbjct: 75 EPSIDTKNIGLRGIPVADTRISNIDGKQGRLIYRGYDISD----LSSKSNFEE-----VA 125
Query: 403 WLLVTGDIPTEAQAKALSKEWAARAELPAHVVTMLNNMPGKLHPMSQFSAAVTALNSESK 582
+LL+ +PT+ + A + +P + + N PM A V AL
Sbjct: 126 YLLLHDGLPTKDRLSAFNSRLVEARWIPKQMQINMGNWRKDADPMDMLQAFVAAL----- 180
Query: 583 FAKAYSXGVHKSKYWEYVYEDTMNLIAKLPVIAATIYR 696
Y +K E Y+ +NLI K+P I A+ +R
Sbjct: 181 --AGYYDEEFANK--EASYDRAINLIGKVPTIVASWHR 214
>UniRef50_Q63TQ8 Cluster: Dihydrolipoamide succinyltransferase
component of 2-oxoglutarate dehydrogenase complex; n=42;
Proteobacteria|Rep: Dihydrolipoamide succinyltransferase
component of 2-oxoglutarate dehydrogenase complex -
Burkholderia pseudomallei (Pseudomonas pseudomallei)
Length = 425
Score = 33.5 bits (73), Expect = 5.4
Identities = 19/56 (33%), Positives = 27/56 (48%)
Frame = +1
Query: 427 PTEAQAKALSKEWAARAELPAHVVTMLNNMPGKLHPMSQFSAAVTALNSESKFAKA 594
P A AKA +K ++PA T LN+ P + PMS+ A + ES+ A
Sbjct: 165 PAAAPAKAAAKPALPEVKVPASATTWLNDRPEQRVPMSRLRARIAERLLESQQTNA 220
>UniRef50_Q4P943 Cluster: Predicted protein; n=1; Ustilago
maydis|Rep: Predicted protein - Ustilago maydis (Smut
fungus)
Length = 283
Score = 33.5 bits (73), Expect = 5.4
Identities = 15/24 (62%), Positives = 15/24 (62%)
Frame = +2
Query: 134 EFKKYSPGKDSQGNKRRSANSERS 205
EFKKY D GNKRRS S RS
Sbjct: 94 EFKKYQAKDDKDGNKRRSPRSRRS 117
>UniRef50_Q2PPA5 Cluster: Geranylgeranyl diphosphate synthase; n=3;
Gibberella fujikuroi complex|Rep: Geranylgeranyl
diphosphate synthase - Gibberella intermedia (Bulb rot
disease fungus) (Fusariumproliferatum)
Length = 392
Score = 33.5 bits (73), Expect = 5.4
Identities = 28/89 (31%), Positives = 44/89 (49%), Gaps = 6/89 (6%)
Frame = +1
Query: 412 VTGDIPTEAQAKALSKEWAARAELPA--HVVTMLNNMPGKLHPMSQFSAAVTALNSESKF 585
VTG I T Q +A+ W A A +P+ + M+N+ G L + S + ALNSE+
Sbjct: 198 VTGTITTIFQGQAMDLWWTANAIVPSIQEYLLMVNDETGALF---RLSLELLALNSEASI 254
Query: 586 A----KAYSXGVHKSKYWEYVYEDTMNLI 660
+ ++ S V + + +D MNLI
Sbjct: 255 SDSALESLSSAVSLLGQYFQIRDDYMNLI 283
>UniRef50_P42457 Cluster: Citrate synthase; n=10;
Actinobacteridae|Rep: Citrate synthase - Corynebacterium
glutamicum (Brevibacterium flavum)
Length = 437
Score = 33.5 bits (73), Expect = 5.4
Identities = 33/135 (24%), Positives = 63/135 (46%), Gaps = 1/135 (0%)
Frame = +1
Query: 295 LDADEGI-RFRGLSIPECQQQLPKAKGGEEPLPEGLFWLLVTGDIPTEAQAKALSKEWAA 471
+D D GI R+RG I + + A E + +LL+ G++PT + + E
Sbjct: 68 IDGDAGILRYRGYDIADLAEN---ATFNE------VSYLLINGELPTPDELHKFNDEIRH 118
Query: 472 RAELPAHVVTMLNNMPGKLHPMSQFSAAVTALNSESKFAKAYSXGVHKSKYWEYVYEDTM 651
L + N P HPM+ +++V L S + + + +++ + + T+
Sbjct: 119 HTLLDEDFKSQFNVFPRDAHPMATLASSVNIL---STYYQDQLNPLDEAQ----LDKATV 171
Query: 652 NLIAKLPVIAATIYR 696
L+AK+P++AA +R
Sbjct: 172 RLMAKVPMLAAYAHR 186
>UniRef50_Q9XBT3 Cluster: PrpC; n=12; cellular organisms|Rep: PrpC -
Legionella pneumophila
Length = 372
Score = 33.1 bits (72), Expect = 7.1
Identities = 32/120 (26%), Positives = 54/120 (45%), Gaps = 4/120 (3%)
Frame = +1
Query: 250 GGMRGI-KGLVWETSVLDADEGIRFRGLSIPECQQQLPKAKGGEEPLPEGLFWLLVTGDI 426
GG+ G+ G +V A +G+ +RG SI + L + EE + +LL G++
Sbjct: 6 GGLAGVVAGQSAIATVGLAGKGLNYRGYSIND----LAEYASFEE-----VAYLLHYGEL 56
Query: 427 PTEAQAKALSKEWAARAELPAHVVTMLNNMPGKLHPMSQFSAAVTALNS---ESKFAKAY 597
PT+ + K+ +P + T+L +P HPM A + L + E F + Y
Sbjct: 57 PTQKELDVYIKKLVNLRHIPDVLKTVLKLIPKNTHPMDVLRTACSFLGTIEPEENFKQQY 116
>UniRef50_A2DLI0 Cluster: Putative uncharacterized protein; n=1;
Trichomonas vaginalis G3|Rep: Putative uncharacterized
protein - Trichomonas vaginalis G3
Length = 314
Score = 32.7 bits (71), Expect = 9.4
Identities = 16/41 (39%), Positives = 22/41 (53%)
Frame = +1
Query: 520 GKLHPMSQFSAAVTALNSESKFAKAYSXGVHKSKYWEYVYE 642
GK ++ FS V L S S F Y+ VH +KY ++YE
Sbjct: 33 GKSSLIANFSPEVKELQSRSTFGYEYTDFVHDNKYLIHIYE 73
>UniRef50_Q0CQ68 Cluster: Predicted protein; n=1; Aspergillus
terreus NIH2624|Rep: Predicted protein - Aspergillus
terreus (strain NIH 2624)
Length = 479
Score = 32.7 bits (71), Expect = 9.4
Identities = 19/63 (30%), Positives = 31/63 (49%)
Frame = +1
Query: 235 VDMMYGGMRGIKGLVWETSVLDADEGIRFRGLSIPECQQQLPKAKGGEEPLPEGLFWLLV 414
V ++ G + G+ G+VW + + A + +PE ++LP G LP GLFW
Sbjct: 320 VSLLVGVLIGLSGMVWWSLTVFARQINSTPDKIVPE--RRLPPMMAGAVGLPIGLFWFAW 377
Query: 415 TGD 423
T +
Sbjct: 378 TSN 380
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 732,873,318
Number of Sequences: 1657284
Number of extensions: 14737363
Number of successful extensions: 45352
Number of sequences better than 10.0: 51
Number of HSP's better than 10.0 without gapping: 43512
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 45312
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 58677691418
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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