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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= brP-0121
         (773 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_A1Z903 Cluster: CG30051-PB; n=9; Endopterygota|Rep: CG3...   157   2e-37
UniRef50_Q96B42 Cluster: Transmembrane protein 18; n=14; Tetrapo...   114   2e-24
UniRef50_Q641M3 Cluster: Transmembrane protein 18; n=1; Danio re...   111   2e-23
UniRef50_UPI00005A31C6 Cluster: PREDICTED: similar to transmembr...   109   6e-23
UniRef50_Q67Y14 Cluster: MRNA, complete cds, clone: RAFL25-19-D0...    94   4e-18
UniRef50_UPI0000E4A779 Cluster: PREDICTED: similar to predicted ...    83   1e-14
UniRef50_Q5DBE4 Cluster: SJCHGC02446 protein; n=1; Schistosoma j...    82   2e-14
UniRef50_A7SVN3 Cluster: Predicted protein; n=1; Nematostella ve...    78   2e-13
UniRef50_Q019C7 Cluster: Chromosome 05 contig 1, DNA sequence; n...    63   6e-09
UniRef50_Q4DAM3 Cluster: Putative uncharacterized protein; n=2; ...    50   5e-05
UniRef50_Q381E2 Cluster: Putative uncharacterized protein; n=1; ...    37   0.64 
UniRef50_Q4Q4P9 Cluster: Putative uncharacterized protein; n=3; ...    36   1.1  
UniRef50_Q20250 Cluster: Putative uncharacterized protein; n=2; ...    34   4.5  
UniRef50_UPI0000D9D2BF Cluster: PREDICTED: similar to transmembr...    33   7.9  

>UniRef50_A1Z903 Cluster: CG30051-PB; n=9; Endopterygota|Rep:
           CG30051-PB - Drosophila melanogaster (Fruit fly)
          Length = 189

 Score =  157 bits (382), Expect = 2e-37
 Identities = 70/140 (50%), Positives = 94/140 (67%)
 Frame = +2

Query: 110 LKLTSISDFVSXLXXIXWRDPWXIALISFHIIITVTCFSTRNYGNFQVXXXXXXXXXVYF 289
           +++  I+ + + L  I W+DPW I LI  HI+ T T   +RN  NFQV         VYF
Sbjct: 44  IEVNEINGYWTFLLSIDWKDPWLIGLILAHILTTTTALLSRNSSNFQVFLFLVLLLAVYF 103

Query: 290 SENINELAARNWALFSRQQYFDSKGLFISXVFSIPILLNCMIMVGSWLYQSTQIMTNLKK 469
           +E+INE AA NW+ FSRQQYFDS GLFIS VFSIPILLNCM+++G+WLY STQ+M  LK 
Sbjct: 104 TESINEFAANNWSSFSRQQYFDSNGLFISTVFSIPILLNCMLLIGTWLYNSTQLMVTLKT 163

Query: 470 AQLRQRLKEMNSIREQQQHV 529
           AQL++R ++    +   + +
Sbjct: 164 AQLKERARKERQTKADSESI 183


>UniRef50_Q96B42 Cluster: Transmembrane protein 18; n=14;
           Tetrapoda|Rep: Transmembrane protein 18 - Homo sapiens
           (Human)
          Length = 140

 Score =  114 bits (275), Expect = 2e-24
 Identities = 52/113 (46%), Positives = 77/113 (68%), Gaps = 1/113 (0%)
 Frame = +2

Query: 161 WRDPWXIALISFHII-ITVTCFSTRNYGNFQVXXXXXXXXXVYFSENINELAARNWALFS 337
           W +PW + L +FH + + +TC S+R+Y   Q+         VY +E INE AA NW LFS
Sbjct: 23  WTEPWLMGLATFHALCVLLTCLSSRSY-RLQIGHFLCLVILVYCAEYINEAAAMNWRLFS 81

Query: 338 RQQYFDSKGLFISXVFSIPILLNCMIMVGSWLYQSTQIMTNLKKAQLRQRLKE 496
           + QYFDS+G+FIS VFS P+L+N MI+V  W++++  +MT+LK AQ R++ K+
Sbjct: 82  KYQYFDSRGMFISIVFSAPLLVNAMIIVVMWVWKTLNVMTDLKNAQERRKEKK 134


>UniRef50_Q641M3 Cluster: Transmembrane protein 18; n=1; Danio
           rerio|Rep: Transmembrane protein 18 - Danio rerio
           (Zebrafish) (Brachydanio rerio)
          Length = 152

 Score =  111 bits (266), Expect = 2e-23
 Identities = 53/138 (38%), Positives = 83/138 (60%)
 Frame = +2

Query: 104 NSLKLTSISDFVSXLXXIXWRDPWXIALISFHIIITVTCFSTRNYGNFQVXXXXXXXXXV 283
           +++++TSI  F   L  + W +PW +AL++FH+        +  Y   Q+         V
Sbjct: 18  SNVRITSIWTF---LQSVDWSEPWLMALLAFHVFCFAFTLLSCKYYRIQICHFLLMVAMV 74

Query: 284 YFSENINELAARNWALFSRQQYFDSKGLFISXVFSIPILLNCMIMVGSWLYQSTQIMTNL 463
           Y +E +NELAA NW  FS+ QYFDSKG+FIS V+S+P+LLN +I+V  W++++   MT L
Sbjct: 75  YSAEYLNELAAMNWRSFSKFQYFDSKGMFISLVYSVPLLLNTVIIVAVWVWRTFSTMTEL 134

Query: 464 KKAQLRQRLKEMNSIREQ 517
           K  QL+++    N  + Q
Sbjct: 135 KILQLKRKAARENHKKTQ 152


>UniRef50_UPI00005A31C6 Cluster: PREDICTED: similar to transmembrane
           protein 18; n=2; Theria|Rep: PREDICTED: similar to
           transmembrane protein 18 - Canis familiaris
          Length = 411

 Score =  109 bits (263), Expect = 6e-23
 Identities = 51/110 (46%), Positives = 73/110 (66%), Gaps = 1/110 (0%)
 Frame = +2

Query: 161 WRDPWXIALISFHII-ITVTCFSTRNYGNFQVXXXXXXXXXVYFSENINELAARNWALFS 337
           W +PW + L  FH++ + +TC S++ Y   QV         VY +E INE+AA NW LFS
Sbjct: 296 WTEPWLLGLAVFHVLCLLLTCLSSQRY-KLQVGHFLCLVILVYCAEYINEIAAMNWRLFS 354

Query: 338 RQQYFDSKGLFISXVFSIPILLNCMIMVGSWLYQSTQIMTNLKKAQLRQR 487
           + QYFDS+G+FIS VFS P+LLN MI+V  W+ ++  +MT+LK  Q ++R
Sbjct: 355 KYQYFDSRGMFISIVFSAPLLLNAMIIVILWVRKTLNVMTDLKTLQEKRR 404


>UniRef50_Q67Y14 Cluster: MRNA, complete cds, clone: RAFL25-19-D04;
           n=7; Magnoliophyta|Rep: MRNA, complete cds, clone:
           RAFL25-19-D04 - Arabidopsis thaliana (Mouse-ear cress)
          Length = 163

 Score = 93.9 bits (223), Expect = 4e-18
 Identities = 40/121 (33%), Positives = 71/121 (58%)
 Frame = +2

Query: 131 DFVSXLXXIXWRDPWXIALISFHIIITVTCFSTRNYGNFQVXXXXXXXXXVYFSENINEL 310
           +F+     I W++PW + L++FH ++ +    +R + NF +         VYF+EN+N  
Sbjct: 36  NFLGFFHAIDWKEPWIMGLMAFHALLLLVTLLSRRHLNFHMFLFLLALAGVYFAENLNRE 95

Query: 311 AARNWALFSRQQYFDSKGLFISXVFSIPILLNCMIMVGSWLYQSTQIMTNLKKAQLRQRL 490
             +NW  FS Q YFDS G+F+S ++S P+L+  MI++ + L+    ++   K+A+LR R 
Sbjct: 96  LRKNWKSFSTQNYFDSNGVFLSTLWSGPLLVIAMIILINTLFSLCYLIVKWKRAELRHRA 155

Query: 491 K 493
           +
Sbjct: 156 R 156


>UniRef50_UPI0000E4A779 Cluster: PREDICTED: similar to predicted
           membrane protein; n=1; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to predicted membrane
           protein - Strongylocentrotus purpuratus
          Length = 96

 Score = 82.6 bits (195), Expect = 1e-14
 Identities = 32/80 (40%), Positives = 61/80 (76%), Gaps = 1/80 (1%)
 Frame = +2

Query: 281 VYFSENINELAARNWALFSRQQYFDSKGLFISXVFSIPILLNCMIMVGSWLYQSTQIMTN 460
           +Y SE +N+ AA+++ +FSR QYFDS GLFIS V+++P+L+NC++M+  WL+ +  ++ +
Sbjct: 5   IYLSEYLNQYAAKHYRMFSRLQYFDSGGLFISVVYNVPLLINCLVMICIWLHTAAHMVVS 64

Query: 461 LKKAQLRQRLK-EMNSIREQ 517
           +K+ +L+++ K E + I ++
Sbjct: 65  VKRGKLKEKAKSEASEIEDK 84


>UniRef50_Q5DBE4 Cluster: SJCHGC02446 protein; n=1; Schistosoma
           japonicum|Rep: SJCHGC02446 protein - Schistosoma
           japonicum (Blood fluke)
          Length = 143

 Score = 81.8 bits (193), Expect = 2e-14
 Identities = 40/112 (35%), Positives = 64/112 (57%), Gaps = 1/112 (0%)
 Frame = +2

Query: 155 IXWRDP-WXIALISFHIIITVTCFSTRNYGNFQVXXXXXXXXXVYFSENINELAARNWAL 331
           I WR+  W ++LI FHI+ +V     R   NF +         V+ S+ INELAA  W +
Sbjct: 26  ISWRNELWLVSLIGFHILTSVCIIVLRKRTNFLLCILFIFLGTVWCSQWINELAASYWNM 85

Query: 332 FSRQQYFDSKGLFISXVFSIPILLNCMIMVGSWLYQSTQIMTNLKKAQLRQR 487
           F+ +QYFDS G FIS ++SIP++LN + ++   + Q   ++   K+ Q+  +
Sbjct: 86  FATEQYFDSYGYFISCIWSIPVILNSLTIIVLLVLQINSLVVQSKRLQVANK 137


>UniRef50_A7SVN3 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 121

 Score = 78.2 bits (184), Expect = 2e-13
 Identities = 30/73 (41%), Positives = 52/73 (71%)
 Frame = +2

Query: 281 VYFSENINELAARNWALFSRQQYFDSKGLFISXVFSIPILLNCMIMVGSWLYQSTQIMTN 460
           VY SE +N L  R+W  F+R+QYFDS GLFIS + S+P+L NC +++ SWL+ +  ++  
Sbjct: 36  VYASEQLNILGERHWRKFAREQYFDSSGLFISVILSVPVLFNCFVILVSWLWTACSMLIV 95

Query: 461 LKKAQLRQRLKEM 499
           + K ++R++ +++
Sbjct: 96  VGKGRVREKQRQL 108


>UniRef50_Q019C7 Cluster: Chromosome 05 contig 1, DNA sequence; n=2;
           Ostreococcus|Rep: Chromosome 05 contig 1, DNA sequence -
           Ostreococcus tauri
          Length = 155

 Score = 63.3 bits (147), Expect = 6e-09
 Identities = 31/114 (27%), Positives = 55/114 (48%)
 Frame = +2

Query: 155 IXWRDPWXIALISFHIIITVTCFSTRNYGNFQVXXXXXXXXXVYFSENINELAARNWALF 334
           + W + W   L+  H+ + +   STR     Q          V  +E IN L   +W  F
Sbjct: 40  VDWSEGWLKLLLCAHVCLFIAIASTRGSDRAQGGLFCICVVVVLAAERINSLGDAHWETF 99

Query: 335 SRQQYFDSKGLFISXVFSIPILLNCMIMVGSWLYQSTQIMTNLKKAQLRQRLKE 496
           + Q YFD +G FIS V S P+++  + ++ + LY  T +M  + + + +  +K+
Sbjct: 100 ASQNYFDKRGRFISIVLSTPLVVATLFILVNLLYIMTGMMVEVARKRRKTGVKK 153


>UniRef50_Q4DAM3 Cluster: Putative uncharacterized protein; n=2;
           Trypanosoma cruzi|Rep: Putative uncharacterized protein
           - Trypanosoma cruzi
          Length = 208

 Score = 50.4 bits (115), Expect = 5e-05
 Identities = 37/129 (28%), Positives = 61/129 (47%), Gaps = 5/129 (3%)
 Frame = +2

Query: 125 ISDFVSXLXXIXWRDPWXIALISFH--IIITVTCFSTRNYGNFQVXXXXXXXXXVYFSEN 298
           +SDFV+    + W +P+   L  FH  +I+ V   + R                 + S  
Sbjct: 49  VSDFVAA---VNWSEPFFTYLALFHTLVIVLVLVLTWRASAERIFVVAFFVLLLGWCSSY 105

Query: 299 INELAARNWA-LFSRQ--QYFDSKGLFISXVFSIPILLNCMIMVGSWLYQSTQIMTNLKK 469
           +NE    + A +F  +   YFD  GLFIS V+  PI L  +++ G  L Q  ++M + K+
Sbjct: 106 LNEYGRLHAAEIFVEKGVNYFDRGGLFISVVYFCPIFLVALLLQGRILLQMLRLMVDTKR 165

Query: 470 AQLRQRLKE 496
            QLR+ + +
Sbjct: 166 RQLRKEMAD 174


>UniRef50_Q381E2 Cluster: Putative uncharacterized protein; n=1;
           Trypanosoma brucei|Rep: Putative uncharacterized protein
           - Trypanosoma brucei
          Length = 190

 Score = 36.7 bits (81), Expect = 0.64
 Identities = 26/127 (20%), Positives = 56/127 (44%), Gaps = 5/127 (3%)
 Frame = +2

Query: 131 DFVSXLXXIXWRDPWXIALISFHIIITVTCFSTRNYGNFQ--VXXXXXXXXXVYFSENIN 304
           +  + +  + W +P+   L  FH+ + VT   T    +              V+ S  +N
Sbjct: 46  EVAAFISAVNWWEPYFRYLALFHLTVAVTVVLTTWRASIDRIFVVTVLLLLVVWGSSYLN 105

Query: 305 ELAARNWA-LFSRQ--QYFDSKGLFISXVFSIPILLNCMIMVGSWLYQSTQIMTNLKKAQ 475
           E  + + + +F  +   YFD  GLFI     +P+ L  + +      Q  ++M  +K+ Q
Sbjct: 106 EWGSSHASQIFVEKGANYFDPSGLFIMVTLDMPLFLLVLWLQARAFLQLLRLMVVVKRNQ 165

Query: 476 LRQRLKE 496
           +++ +++
Sbjct: 166 IKREMEK 172


>UniRef50_Q4Q4P9 Cluster: Putative uncharacterized protein; n=3;
           Leishmania|Rep: Putative uncharacterized protein -
           Leishmania major
          Length = 205

 Score = 35.9 bits (79), Expect = 1.1
 Identities = 30/122 (24%), Positives = 55/122 (45%), Gaps = 8/122 (6%)
 Frame = +2

Query: 155 IXWRDPWXIALISFHIIITVTCFSTRNYG--NFQVXXXXXXXXXVYFSENI--NELAARN 322
           + W +P+   +  FH+++ V    T  +G  + +          V     I  N  A R+
Sbjct: 63  VNWSEPFFRYIGVFHVVVWVAAI-TATWGAVSDERIMAVCAVLGVLLLSGIPANSYAGRH 121

Query: 323 --WALFSRQ--QYFDSKGLFISXVFSIPILLNCMIMVGSWLYQSTQIMTNLKKAQLRQRL 490
             W LF      YF   G  +  V+ +P+L+  + +     Y+   +M  LK+AQLR+R+
Sbjct: 122 AEW-LFQEPGVNYFTEDGTMLMVVYLLPLLVLLVYLQLRQGYRVVSLMVRLKRAQLRRRM 180

Query: 491 KE 496
           ++
Sbjct: 181 RQ 182


>UniRef50_Q20250 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 264

 Score = 33.9 bits (74), Expect = 4.5
 Identities = 16/45 (35%), Positives = 23/45 (51%)
 Frame = -3

Query: 384 NTXDINRPLLSKYCCLENNAQFLAASSFIFSEKYTSKRSMIKSIT 250
           NT D   P LSKY CLEN + F     ++      S R  ++++T
Sbjct: 194 NTIDKELPDLSKYRCLENRSFFKKTPEYMCERYRNSNRECLRAVT 238


>UniRef50_UPI0000D9D2BF Cluster: PREDICTED: similar to transmembrane
           protein 18; n=1; Macaca mulatta|Rep: PREDICTED: similar
           to transmembrane protein 18 - Macaca mulatta
          Length = 205

 Score = 33.1 bits (72), Expect = 7.9
 Identities = 11/27 (40%), Positives = 19/27 (70%), Gaps = 1/27 (3%)
 Frame = +2

Query: 161 WRDPWXIALISFH-IIITVTCFSTRNY 238
           W +PW + L +FH + + +TC S+R+Y
Sbjct: 69  WTEPWLMGLAAFHALCLLLTCLSSRSY 95


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 606,284,531
Number of Sequences: 1657284
Number of extensions: 10842903
Number of successful extensions: 22420
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 21727
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 22406
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 65027411410
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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