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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= brP-0118
         (775 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

AY101765-1|AAM50084.1| 1885|Homo sapiens C3 and PZP-like alpha-2...    89   1e-17
AB033109-1|BAA86597.1| 1884|Homo sapiens KIAA1283 protein protein.     89   1e-17
BC070047-1|AAH70047.1|  331|Homo sapiens epilepsy, progressive m...    31   3.5  
AL365193-1|CAI21675.1|  331|Homo sapiens epilepsy, progressive m...    31   3.5  
AL023806-1|CAI21419.1|  331|Homo sapiens epilepsy, progressive m...    31   3.5  
AF284580-1|AAG18377.1|  331|Homo sapiens progressive myoclonus e...    31   3.5  
AF084535-1|AAC83347.2|  331|Homo sapiens laforin protein.              31   3.5  
AF485466-1|AAL96553.1|  104|Homo sapiens immunoglobulin light ch...    31   6.1  
AF485464-1|AAL96551.1|  104|Homo sapiens immunoglobulin light ch...    31   6.1  
AF485458-1|AAL96545.1|  104|Homo sapiens immunoglobulin light ch...    31   6.1  
AJ404468-1|CAB94756.1| 4486|Homo sapiens axonemal dynein heavy c...    30   8.0  
AF485474-1|AAL96561.1|  104|Homo sapiens immunoglobulin light ch...    30   8.0  
AF257737-1|AAF69004.1| 4486|Homo sapiens ciliary dynein heavy ch...    30   8.0  

>AY101765-1|AAM50084.1| 1885|Homo sapiens C3 and PZP-like
            alpha-2-macroglobulin domain containing 8 protein.
          Length = 1885

 Score = 89.4 bits (212), Expect = 1e-17
 Identities = 46/144 (31%), Positives = 76/144 (52%), Gaps = 5/144 (3%)
 Frame = +1

Query: 28   VATDDNLQYQFF--PVSSGSVQFKVRAANDAHVALTTGPQESDPMYEVMIGGWGNAKSVI 201
            ++T +  ++Q+   P+        VRA NDA VAL++GPQ++  M E+++GG  N +S I
Sbjct: 953  ISTPNKYEFQYVQRPLRLTRFDVAVRAHNDARVALSSGPQDTAGMIEIVLGGHQNTRSWI 1012

Query: 202  RKNRTKPDKVEIESPGILNGGEYRGFWVRWDSGIISAGREGE---AIPFISWSDPEPFPV 372
              ++         +  IL+  E+R FW+ W  G+I  G   E       ++W+ P P  V
Sbjct: 1013 STSKMGEPVASAHTAKILSWDEFRTFWISWRGGLIQVGHGPEPSNESVIVAWTLPRPPEV 1072

Query: 373  YYVGVCTGWGATGSWKIEDGAEFD 444
             ++G  TGWG+ G ++I    E D
Sbjct: 1073 QFIGFSTGWGSMGEFRIWRKMEVD 1096



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 27/103 (26%), Positives = 51/103 (49%), Gaps = 3/103 (2%)
 Frame = +1

Query: 445  TPDRLXYKF--GPVASGSLEFDYRGPHNCHVSLTTHPAXVDPMYEIIIGGWENTQSVIRY 618
            TP++  +++   P+     +   R  ++  V+L++ P     M EI++GG +NT+S I  
Sbjct: 955  TPNKYEFQYVQRPLRLTRFDVAVRAHNDARVALSSGPQDTAGMIEIVLGGHQNTRSWIST 1014

Query: 619  CRQKPDKVTIPTPGIMNPNEFXXFLIEWKCXXL-VGA*PDVGN 744
             +      +  T  I++ +EF  F I W+   + VG  P+  N
Sbjct: 1015 SKMGEPVASAHTAKILSWDEFRTFWISWRGGLIQVGHGPEPSN 1057


>AB033109-1|BAA86597.1| 1884|Homo sapiens KIAA1283 protein protein.
          Length = 1884

 Score = 89.4 bits (212), Expect = 1e-17
 Identities = 46/144 (31%), Positives = 76/144 (52%), Gaps = 5/144 (3%)
 Frame = +1

Query: 28   VATDDNLQYQFF--PVSSGSVQFKVRAANDAHVALTTGPQESDPMYEVMIGGWGNAKSVI 201
            ++T +  ++Q+   P+        VRA NDA VAL++GPQ++  M E+++GG  N +S I
Sbjct: 952  ISTPNKYEFQYVQRPLRLTRFDVAVRAHNDARVALSSGPQDTAGMIEIVLGGHQNTRSWI 1011

Query: 202  RKNRTKPDKVEIESPGILNGGEYRGFWVRWDSGIISAGREGE---AIPFISWSDPEPFPV 372
              ++         +  IL+  E+R FW+ W  G+I  G   E       ++W+ P P  V
Sbjct: 1012 STSKMGEPVASAHTAKILSWDEFRTFWISWRGGLIQVGHGPEPSNESVIVAWTLPRPPEV 1071

Query: 373  YYVGVCTGWGATGSWKIEDGAEFD 444
             ++G  TGWG+ G ++I    E D
Sbjct: 1072 QFIGFSTGWGSMGEFRIWRKMEVD 1095



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 27/103 (26%), Positives = 51/103 (49%), Gaps = 3/103 (2%)
 Frame = +1

Query: 445  TPDRLXYKF--GPVASGSLEFDYRGPHNCHVSLTTHPAXVDPMYEIIIGGWENTQSVIRY 618
            TP++  +++   P+     +   R  ++  V+L++ P     M EI++GG +NT+S I  
Sbjct: 954  TPNKYEFQYVQRPLRLTRFDVAVRAHNDARVALSSGPQDTAGMIEIVLGGHQNTRSWIST 1013

Query: 619  CRQKPDKVTIPTPGIMNPNEFXXFLIEWKCXXL-VGA*PDVGN 744
             +      +  T  I++ +EF  F I W+   + VG  P+  N
Sbjct: 1014 SKMGEPVASAHTAKILSWDEFRTFWISWRGGLIQVGHGPEPSN 1056


>BC070047-1|AAH70047.1|  331|Homo sapiens epilepsy, progressive
           myoclonus type 2A, Lafora disease (laforin) protein.
          Length = 331

 Score = 31.5 bits (68), Expect = 3.5
 Identities = 19/57 (33%), Positives = 25/57 (43%), Gaps = 1/57 (1%)
 Frame = +1

Query: 424 EDGAEFDTPDRLXYKF-GPVASGSLEFDYRGPHNCHVSLTTHPAXVDPMYEIIIGGW 591
           +DGAE    D   YKF      G L ++  GPH+           VD +Y + IG W
Sbjct: 73  QDGAEPGRVDTFWYKFLKREPGGELSWEGNGPHHDRCCTYNENNLVDGVYCLPIGHW 129


>AL365193-1|CAI21675.1|  331|Homo sapiens epilepsy, progressive
           myoclonus type 2A, Lafora disease (laforin) protein.
          Length = 331

 Score = 31.5 bits (68), Expect = 3.5
 Identities = 19/57 (33%), Positives = 25/57 (43%), Gaps = 1/57 (1%)
 Frame = +1

Query: 424 EDGAEFDTPDRLXYKF-GPVASGSLEFDYRGPHNCHVSLTTHPAXVDPMYEIIIGGW 591
           +DGAE    D   YKF      G L ++  GPH+           VD +Y + IG W
Sbjct: 73  QDGAEPGRVDTFWYKFLKREPGGELSWEGNGPHHDRCCTYNENNLVDGVYCLPIGHW 129


>AL023806-1|CAI21419.1|  331|Homo sapiens epilepsy, progressive
           myoclonus type 2A, Lafora disease (laforin) protein.
          Length = 331

 Score = 31.5 bits (68), Expect = 3.5
 Identities = 19/57 (33%), Positives = 25/57 (43%), Gaps = 1/57 (1%)
 Frame = +1

Query: 424 EDGAEFDTPDRLXYKF-GPVASGSLEFDYRGPHNCHVSLTTHPAXVDPMYEIIIGGW 591
           +DGAE    D   YKF      G L ++  GPH+           VD +Y + IG W
Sbjct: 73  QDGAEPGRVDTFWYKFLKREPGGELSWEGNGPHHDRCCTYNENNLVDGVYCLPIGHW 129


>AF284580-1|AAG18377.1|  331|Homo sapiens progressive myoclonus
           epilepsy type 2 protein.
          Length = 331

 Score = 31.5 bits (68), Expect = 3.5
 Identities = 19/57 (33%), Positives = 25/57 (43%), Gaps = 1/57 (1%)
 Frame = +1

Query: 424 EDGAEFDTPDRLXYKF-GPVASGSLEFDYRGPHNCHVSLTTHPAXVDPMYEIIIGGW 591
           +DGAE    D   YKF      G L ++  GPH+           VD +Y + IG W
Sbjct: 73  QDGAEPGRVDTFWYKFLKREPGGELSWEGNGPHHDRCCTYNENNLVDGVYCLPIGHW 129


>AF084535-1|AAC83347.2|  331|Homo sapiens laforin protein.
          Length = 331

 Score = 31.5 bits (68), Expect = 3.5
 Identities = 19/57 (33%), Positives = 25/57 (43%), Gaps = 1/57 (1%)
 Frame = +1

Query: 424 EDGAEFDTPDRLXYKF-GPVASGSLEFDYRGPHNCHVSLTTHPAXVDPMYEIIIGGW 591
           +DGAE    D   YKF      G L ++  GPH+           VD +Y + IG W
Sbjct: 73  QDGAEPGRVDTFWYKFLKREPGGELSWEGNGPHHDRCCTYNENNLVDGVYCLPIGHW 129


>AF485466-1|AAL96553.1|  104|Homo sapiens immunoglobulin light chain
           variable region protein.
          Length = 104

 Score = 30.7 bits (66), Expect = 6.1
 Identities = 14/29 (48%), Positives = 16/29 (55%)
 Frame = +1

Query: 340 ISWSDPEPFPVYYVGVCTGWGATGSWKIE 426
           IS  DPE F VYY    + WG  G  K+E
Sbjct: 73  ISSLDPEDFAVYYCQQRSNWGFGGGTKVE 101


>AF485464-1|AAL96551.1|  104|Homo sapiens immunoglobulin light chain
           variable region protein.
          Length = 104

 Score = 30.7 bits (66), Expect = 6.1
 Identities = 14/29 (48%), Positives = 16/29 (55%)
 Frame = +1

Query: 340 ISWSDPEPFPVYYVGVCTGWGATGSWKIE 426
           IS  +PE F VYY    T WG  G  K+E
Sbjct: 73  ISSLEPEDFAVYYCQQRTNWGFGGGTKVE 101


>AF485458-1|AAL96545.1|  104|Homo sapiens immunoglobulin light chain
           variable region protein.
          Length = 104

 Score = 30.7 bits (66), Expect = 6.1
 Identities = 14/29 (48%), Positives = 16/29 (55%)
 Frame = +1

Query: 340 ISWSDPEPFPVYYVGVCTGWGATGSWKIE 426
           IS  +PE F VYY    T WG  G  K+E
Sbjct: 73  ISSLEPEDFAVYYCQQRTNWGFGGGTKVE 101


>AJ404468-1|CAB94756.1| 4486|Homo sapiens axonemal dynein heavy
           chain 9 protein.
          Length = 4486

 Score = 30.3 bits (65), Expect = 8.0
 Identities = 22/55 (40%), Positives = 28/55 (50%), Gaps = 4/55 (7%)
 Frame = -3

Query: 248 PGLSISTLSGLV----LFFLMTLLAFPQPPIITSYIGSDSCGPVVSATWASFAAL 96
           PGL +   SGL     LFFL T    P+PP   S+ G+  CG + +A     AAL
Sbjct: 85  PGLEVGPESGLAGAKALFFLRT---GPEPPGPDSFRGAVVCGDLPAAPLEHLAAL 136


>AF485474-1|AAL96561.1|  104|Homo sapiens immunoglobulin light chain
           variable region protein.
          Length = 104

 Score = 30.3 bits (65), Expect = 8.0
 Identities = 14/29 (48%), Positives = 16/29 (55%)
 Frame = +1

Query: 340 ISWSDPEPFPVYYVGVCTGWGATGSWKIE 426
           IS  +PE F VYY    T WG  G  K+E
Sbjct: 73  ISSLEPEDFAVYYCQQRTDWGFGGGTKVE 101


>AF257737-1|AAF69004.1| 4486|Homo sapiens ciliary dynein heavy chain
           9 protein.
          Length = 4486

 Score = 30.3 bits (65), Expect = 8.0
 Identities = 22/55 (40%), Positives = 28/55 (50%), Gaps = 4/55 (7%)
 Frame = -3

Query: 248 PGLSISTLSGLV----LFFLMTLLAFPQPPIITSYIGSDSCGPVVSATWASFAAL 96
           PGL +   SGL     LFFL T    P+PP   S+ G+  CG + +A     AAL
Sbjct: 85  PGLEVGPESGLAGAKALFFLRT---GPEPPGPDSFRGAVVCGDLPAAPLEHLAAL 136


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 123,345,231
Number of Sequences: 237096
Number of extensions: 2891966
Number of successful extensions: 7131
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 6778
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7129
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9367263024
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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