BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= brP-0021 (750 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_Q7PY55 Cluster: ENSANGP00000013280; n=4; Endopterygota|... 238 1e-61 UniRef50_Q6RUR3 Cluster: Putative alcohol dehydrogenase; n=2; Ne... 190 3e-47 UniRef50_UPI0000D57363 Cluster: PREDICTED: similar to hydroxypro... 179 6e-44 UniRef50_Q6NYE8 Cluster: Zgc:56585 protein; n=5; Clupeocephala|R... 169 5e-41 UniRef50_P15428 Cluster: 15-hydroxyprostaglandin dehydrogenase [... 166 4e-40 UniRef50_UPI0000D57364 Cluster: PREDICTED: similar to 15-hydroxy... 165 1e-39 UniRef50_UPI0000D57365 Cluster: PREDICTED: similar to CG4899-PA,... 164 2e-39 UniRef50_UPI000051334A Cluster: PREDICTED: similar to 15-hydroxy... 164 2e-39 UniRef50_UPI0000513348 Cluster: PREDICTED: similar to 15-hydroxy... 161 1e-38 UniRef50_UPI00015B5317 Cluster: PREDICTED: similar to putative a... 161 2e-38 UniRef50_UPI00015B5316 Cluster: PREDICTED: similar to putative a... 159 5e-38 UniRef50_UPI0000E47587 Cluster: PREDICTED: similar to 15-hydroxy... 155 1e-36 UniRef50_UPI00015B42DD Cluster: PREDICTED: similar to putative a... 153 4e-36 UniRef50_A7SGX6 Cluster: Predicted protein; n=1; Nematostella ve... 153 6e-36 UniRef50_UPI0000DB7440 Cluster: PREDICTED: similar to 15-hydroxy... 145 1e-33 UniRef50_UPI0000D5767E Cluster: PREDICTED: similar to 15-hydroxy... 138 1e-31 UniRef50_Q9VV42 Cluster: CG4899-PA, isoform A; n=5; Sophophora|R... 136 5e-31 UniRef50_UPI00015B5FC8 Cluster: PREDICTED: similar to putative a... 130 3e-29 UniRef50_UPI00015B42E5 Cluster: PREDICTED: similar to putative a... 127 3e-28 UniRef50_UPI00015B573D Cluster: PREDICTED: similar to putative a... 126 8e-28 UniRef50_UPI00015B4C63 Cluster: PREDICTED: similar to putative a... 124 2e-27 UniRef50_UPI00015B42E2 Cluster: PREDICTED: similar to putative a... 122 9e-27 UniRef50_Q1HPX6 Cluster: Alcohol dehydrogenase; n=1; Bombyx mori... 120 3e-26 UniRef50_UPI00015B5A58 Cluster: PREDICTED: similar to putative a... 120 5e-26 UniRef50_Q1G151 Cluster: Putative alcohol dehydrogenase; n=1; Bo... 118 1e-25 UniRef50_Q9I7R3 Cluster: CG18814-PA; n=3; Sophophora|Rep: CG1881... 115 1e-24 UniRef50_A3I573 Cluster: Short chain dehydrogenase; n=2; Bacillu... 110 3e-23 UniRef50_Q9NAR7 Cluster: Alcohol dehydrogenase; n=23; Schizophor... 110 4e-23 UniRef50_A4AQP7 Cluster: 3-ketoacyl-(Acyl-carrier-protein) reduc... 109 9e-23 UniRef50_Q5TWK5 Cluster: ENSANGP00000025423; n=1; Anopheles gamb... 108 1e-22 UniRef50_A0G4K1 Cluster: Short-chain dehydrogenase/reductase SDR... 106 5e-22 UniRef50_UPI00015B572C Cluster: PREDICTED: similar to putative a... 106 7e-22 UniRef50_Q67M07 Cluster: Short-chain dehydrogenase; n=2; Bacteri... 106 7e-22 UniRef50_Q026V2 Cluster: Short-chain dehydrogenase/reductase SDR... 105 9e-22 UniRef50_Q737G7 Cluster: Short chain dehydrogenase family protei... 105 2e-21 UniRef50_A6CNE9 Cluster: Cyclohexanol dehydrogenase; n=3; Bacill... 105 2e-21 UniRef50_A1BFL6 Cluster: Short-chain dehydrogenase/reductase SDR... 104 2e-21 UniRef50_Q8CUW5 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 103 4e-21 UniRef50_A1IFS9 Cluster: Short chain dehydrogenase family protei... 103 5e-21 UniRef50_Q4WXH0 Cluster: 15-hydroxyprostaglandin dehydrogenase (... 103 5e-21 UniRef50_Q8ELC2 Cluster: Oxidoreductase; n=2; Bacillaceae|Rep: O... 103 6e-21 UniRef50_P54398 Cluster: Fat body protein 2; n=6; Schizophora|Re... 102 8e-21 UniRef50_Q5P8S6 Cluster: Putative dehydrogenase; n=4; Proteobact... 101 3e-20 UniRef50_Q99714 Cluster: 3-hydroxyacyl-CoA dehydrogenase type-2;... 101 3e-20 UniRef50_Q1IU03 Cluster: Short-chain dehydrogenase/reductase SDR... 99 6e-20 UniRef50_Q8EXX5 Cluster: 3-ketoacyl-acyl carrier protein reducta... 99 1e-19 UniRef50_Q9PCQ2 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 98 2e-19 UniRef50_Q1YQZ7 Cluster: Short chain dehydrogenase family protei... 98 2e-19 UniRef50_A3I6G4 Cluster: Putative 7-alpha-hydroxysteroid dehydro... 98 2e-19 UniRef50_Q7MBD9 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 97 3e-19 UniRef50_Q0LSE4 Cluster: Short-chain dehydrogenase/reductase SDR... 97 4e-19 UniRef50_A0QDR7 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 97 4e-19 UniRef50_Q88LI6 Cluster: Oxidoreductase, short chain dehydrogena... 97 5e-19 UniRef50_A1UMZ0 Cluster: Short-chain dehydrogenase/reductase SDR... 96 7e-19 UniRef50_Q2NIC9 Cluster: Predicted short chain dehydrogenase; n=... 96 7e-19 UniRef50_O18404 Cluster: 3-hydroxyacyl-CoA dehydrogenase type-2;... 96 7e-19 UniRef50_Q929J7 Cluster: Lin2278 protein; n=14; Bacteria|Rep: Li... 96 9e-19 UniRef50_A4ABB5 Cluster: Short-chain dehydrogenase/reductase SDR... 96 9e-19 UniRef50_Q2FSZ0 Cluster: Short-chain dehydrogenase/reductase SDR... 96 9e-19 UniRef50_Q9WYG0 Cluster: Uncharacterized oxidoreductase TM_0325;... 96 9e-19 UniRef50_UPI0000E4700A Cluster: PREDICTED: hypothetical protein,... 95 1e-18 UniRef50_A7HWF2 Cluster: Short-chain dehydrogenase/reductase SDR... 95 1e-18 UniRef50_A1T3E0 Cluster: Short-chain dehydrogenase/reductase SDR... 95 2e-18 UniRef50_Q2J6E1 Cluster: Short-chain dehydrogenase/reductase SDR... 95 2e-18 UniRef50_Q2GA84 Cluster: Short-chain dehydrogenase/reductase SDR... 95 2e-18 UniRef50_Q0LQE1 Cluster: Short-chain dehydrogenase/reductase SDR... 94 3e-18 UniRef50_A6CQ13 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct... 94 3e-18 UniRef50_A4B0K7 Cluster: Short-chain dehydrogenase/oxidoreductas... 94 3e-18 UniRef50_UPI000023E5B7 Cluster: hypothetical protein FG10672.1; ... 94 4e-18 UniRef50_A4XEN1 Cluster: Short-chain dehydrogenase/reductase SDR... 94 4e-18 UniRef50_Q8YHE0 Cluster: GLUCOSE 1-DEHYDROGENASE II; n=4; Brucel... 93 5e-18 UniRef50_Q6LH36 Cluster: Hypothetical oxidoreductase, short-chai... 93 5e-18 UniRef50_A0Z5Q6 Cluster: Short chain dehydrogenase; n=1; marine ... 93 5e-18 UniRef50_Q8F682 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 93 7e-18 UniRef50_A1UEP6 Cluster: Short-chain dehydrogenase/reductase SDR... 93 7e-18 UniRef50_Q9UY54 Cluster: Short-chain alcohol dehydrogenase, puta... 93 7e-18 UniRef50_Q8R9W0 Cluster: Dehydrogenases with different specifici... 93 9e-18 UniRef50_Q8ELN8 Cluster: Glucose 1-dehydrogenase; n=6; cellular ... 93 9e-18 UniRef50_A0H5N7 Cluster: Short-chain dehydrogenase/reductase SDR... 93 9e-18 UniRef50_Q5P686 Cluster: Subunit of 2-[hydroxy(Phenyl)methyl]-su... 92 1e-17 UniRef50_A6W2Y5 Cluster: Short-chain dehydrogenase/reductase SDR... 92 2e-17 UniRef50_A3Q331 Cluster: Short-chain dehydrogenase/reductase SDR... 92 2e-17 UniRef50_A0YFJ9 Cluster: Putative uncharacterized protein; n=1; ... 92 2e-17 UniRef50_A0Y8J3 Cluster: Short chain dehydrogenase; n=1; marine ... 92 2e-17 UniRef50_Q5WBM0 Cluster: Oxidoreductase; n=1; Bacillus clausii K... 91 2e-17 UniRef50_Q3M1E6 Cluster: NAD-dependent epimerase/dehydratase pre... 91 2e-17 UniRef50_Q7VXT8 Cluster: Probable short-chain dehydrogenase; n=3... 91 3e-17 UniRef50_A2U8H9 Cluster: Short-chain dehydrogenase/reductase SDR... 91 3e-17 UniRef50_A7EQI6 Cluster: Putative uncharacterized protein; n=1; ... 91 3e-17 UniRef50_Q9K636 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 91 4e-17 UniRef50_A3CU09 Cluster: Short-chain dehydrogenase/reductase SDR... 91 4e-17 UniRef50_Q5QW23 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 90 5e-17 UniRef50_Q0M0K7 Cluster: Short-chain dehydrogenase/reductase SDR... 90 5e-17 UniRef50_A4M6M0 Cluster: Short-chain dehydrogenase/reductase SDR... 90 5e-17 UniRef50_A1UKM6 Cluster: Short-chain dehydrogenase/reductase SDR... 90 5e-17 UniRef50_P16544 Cluster: Putative ketoacyl reductase; n=42; Bact... 90 5e-17 UniRef50_Q5LDH2 Cluster: Putative 2,5-dichloro-2,5-cyclohexadien... 90 6e-17 UniRef50_Q12DF3 Cluster: Short-chain dehydrogenase/reductase SDR... 90 6e-17 UniRef50_Q0RTV0 Cluster: Short-chain dehydrogenase, SDR family; ... 90 6e-17 UniRef50_A0Z7K1 Cluster: Short-chain dehydrogenase/reductase SDR... 90 6e-17 UniRef50_A0M1K4 Cluster: Short-chain dehydrogenase/reductase fam... 90 6e-17 UniRef50_A7HRW0 Cluster: Short-chain dehydrogenase/reductase SDR... 89 8e-17 UniRef50_A1SJV4 Cluster: Short-chain dehydrogenase/reductase SDR... 89 8e-17 UniRef50_Q4J9F2 Cluster: Short chain dehydrogenase; n=1; Sulfolo... 89 8e-17 UniRef50_P07914 Cluster: Bile acid 7-dehydroxylase 1/3; n=3; Clo... 89 8e-17 UniRef50_Q13E96 Cluster: Short-chain dehydrogenase/reductase SDR... 89 1e-16 UniRef50_Q1NAA1 Cluster: Short-chain dehydrogenase/reductase SDR... 89 1e-16 UniRef50_A1SJM6 Cluster: Short-chain dehydrogenase/reductase SDR... 89 1e-16 UniRef50_Q7SI45 Cluster: Putative uncharacterized protein NCU006... 89 1e-16 UniRef50_P39640 Cluster: Bacilysin biosynthesis oxidoreductase b... 89 1e-16 UniRef50_A7HWN9 Cluster: Short-chain dehydrogenase/reductase SDR... 89 1e-16 UniRef50_A6CM25 Cluster: Oxidoreductase, short chain dehydrogena... 89 1e-16 UniRef50_Q4A054 Cluster: Uncharacterized oxidoreductase SSP0419;... 89 1e-16 UniRef50_Q88T73 Cluster: Short-chain dehydrogenase/oxidoreductas... 88 2e-16 UniRef50_Q5WBV7 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 88 2e-16 UniRef50_Q47PW1 Cluster: Short-chain dehydrogenase/reductase (SD... 88 2e-16 UniRef50_Q11G59 Cluster: Short-chain dehydrogenase/reductase SDR... 88 2e-16 UniRef50_Q11E37 Cluster: Short-chain dehydrogenase/reductase SDR... 88 2e-16 UniRef50_A3BN50 Cluster: Putative uncharacterized protein; n=2; ... 88 2e-16 UniRef50_Q81WX9 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct... 88 2e-16 UniRef50_Q46PX5 Cluster: NAD-dependent epimerase/dehydratase:Sho... 88 2e-16 UniRef50_A4AQP3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 88 2e-16 UniRef50_A3XPR1 Cluster: Cyclohexanol dehydrogenase; n=1; Leeuwe... 88 2e-16 UniRef50_A1ULZ8 Cluster: Short-chain dehydrogenase/reductase SDR... 88 2e-16 UniRef50_Q0DM18 Cluster: Os03g0833100 protein; n=5; Oryza sativa... 88 2e-16 UniRef50_A4QV37 Cluster: Putative uncharacterized protein; n=1; ... 88 2e-16 UniRef50_Q8F0K8 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 87 3e-16 UniRef50_Q5NM60 Cluster: Short-chain alcohol dehydrogenase; n=14... 87 3e-16 UniRef50_Q399N8 Cluster: Short-chain dehydrogenase/reductase SDR... 87 3e-16 UniRef50_Q2IEG2 Cluster: Short-chain dehydrogenase/reductase SDR... 87 3e-16 UniRef50_Q2GA85 Cluster: Short-chain dehydrogenase/reductase SDR... 87 3e-16 UniRef50_Q2G760 Cluster: Short-chain dehydrogenase/reductase SDR... 87 3e-16 UniRef50_Q0SI88 Cluster: Short chain dehydrogenase; n=2; Actinom... 87 3e-16 UniRef50_A1ATN3 Cluster: Short-chain dehydrogenase/reductase SDR... 87 3e-16 UniRef50_Q9FX95 Cluster: ARP protein; n=8; Magnoliophyta|Rep: AR... 87 3e-16 UniRef50_A2QB60 Cluster: Catalytic activity: precursor; n=1; Asp... 87 3e-16 UniRef50_A7DQI5 Cluster: Short-chain dehydrogenase/reductase SDR... 87 3e-16 UniRef50_Q2UEK6 Cluster: Dehydrogenases with different specifici... 87 4e-16 UniRef50_A0RX79 Cluster: Short-chain alcohol dehydrogenase; n=1;... 87 4e-16 UniRef50_Q2JDM5 Cluster: Short-chain dehydrogenase/reductase SDR... 87 6e-16 UniRef50_Q3WGS3 Cluster: Short-chain dehydrogenase/reductase SDR... 87 6e-16 UniRef50_Q3WEN2 Cluster: Short-chain dehydrogenase/reductase SDR... 87 6e-16 UniRef50_Q0RLA9 Cluster: Putative short chain dehydrogenase; n=1... 87 6e-16 UniRef50_Q0FK49 Cluster: FabG3_1; n=1; Roseovarius sp. HTCC2601|... 87 6e-16 UniRef50_A7AZH2 Cluster: Putative uncharacterized protein; n=1; ... 87 6e-16 UniRef50_A0PSR4 Cluster: Short-chain dehydrogenase; n=1; Mycobac... 87 6e-16 UniRef50_A0NRG9 Cluster: Acetoin (Diacetyl) reductase; n=4; Rhod... 87 6e-16 UniRef50_A0K1M9 Cluster: Short-chain dehydrogenase/reductase SDR... 87 6e-16 UniRef50_Q9LW34 Cluster: Alcohol dehydrogenase-like protein; n=6... 87 6e-16 UniRef50_Q930M2 Cluster: Putative; n=4; Bacteria|Rep: Putative -... 86 8e-16 UniRef50_Q89P10 Cluster: Oxidoreductase; n=1; Bradyrhizobium jap... 86 8e-16 UniRef50_Q3WJ78 Cluster: Short-chain dehydrogenase/reductase SDR... 86 8e-16 UniRef50_Q1U845 Cluster: NAD-dependent epimerase/dehydratase:Sho... 86 8e-16 UniRef50_Q13HC1 Cluster: Putative short-chain dehydrogenase/redu... 86 8e-16 UniRef50_Q0RIJ2 Cluster: Putative short chain dehydrogenase/redu... 86 8e-16 UniRef50_A7DM07 Cluster: Short-chain dehydrogenase/reductase SDR... 86 8e-16 UniRef50_A3KJN1 Cluster: Putative 3-oxoacyl-acyl-carrier protein... 86 8e-16 UniRef50_A1UD24 Cluster: Short-chain dehydrogenase/reductase SDR... 86 8e-16 UniRef50_A0JSI8 Cluster: Short-chain dehydrogenase/reductase SDR... 86 8e-16 UniRef50_Q56840 Cluster: 2-(R)-hydroxypropyl-CoM dehydrogenase; ... 86 8e-16 UniRef50_Q46UH5 Cluster: Short-chain dehydrogenase/reductase SDR... 86 1e-15 UniRef50_Q022W9 Cluster: Short-chain dehydrogenase/reductase SDR... 86 1e-15 UniRef50_A7HWE4 Cluster: Short-chain dehydrogenase/reductase SDR... 86 1e-15 UniRef50_A4Z1Y9 Cluster: Putative short-chain dehydrogenases/red... 86 1e-15 UniRef50_A3I4P3 Cluster: Short-chain dehydrogenase/reductase SDR... 86 1e-15 UniRef50_A1UAJ6 Cluster: Acetoin reductases; n=18; Bacteria|Rep:... 86 1e-15 UniRef50_A0QIV9 Cluster: Short chain dehydrogenase; n=5; root|Re... 86 1e-15 UniRef50_Q2U0U8 Cluster: Dehydrogenases with different specifici... 86 1e-15 UniRef50_A1CC09 Cluster: Short chain dehydrogenase/reductase fam... 86 1e-15 UniRef50_P66781 Cluster: Uncharacterized oxidoreductase Rv1350/M... 86 1e-15 UniRef50_Q9LBG2 Cluster: Levodione reductase (EC 1.1.1.-) ((6R)-... 86 1e-15 UniRef50_O67610 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 86 1e-15 UniRef50_Q8KKW9 Cluster: Putative oxidoreductase protein; n=1; R... 85 1e-15 UniRef50_Q82FK0 Cluster: Putative dehydrogenase; n=2; Streptomyc... 85 1e-15 UniRef50_Q1AU84 Cluster: Short-chain dehydrogenase/reductase SDR... 85 1e-15 UniRef50_A6VY27 Cluster: Short-chain dehydrogenase/reductase SDR... 85 1e-15 UniRef50_A4TAB8 Cluster: Short-chain dehydrogenase/reductase SDR... 85 1e-15 UniRef50_A3YE37 Cluster: Short-chain dehydrogenase/reductase SDR... 85 1e-15 UniRef50_A1WKP5 Cluster: Short-chain dehydrogenase/reductase SDR... 85 1e-15 UniRef50_A0R6X9 Cluster: Cyclopentanol dehydrogenase; n=2; Bacte... 85 1e-15 UniRef50_Q49WS9 Cluster: Uncharacterized oxidoreductase SSP1627;... 85 1e-15 UniRef50_Q5KRX7 Cluster: Putative oxidoreductase; n=2; Corynebac... 85 2e-15 UniRef50_Q0C3R5 Cluster: Oxidoreductase, short chain dehydrogena... 85 2e-15 UniRef50_Q56318 Cluster: Uncharacterized oxidoreductase TM_0019;... 85 2e-15 UniRef50_Q59787 Cluster: Sorbitol dehydrogenase; n=60; Bacteria|... 85 2e-15 UniRef50_UPI000045C1E7 Cluster: COG1028: Dehydrogenases with dif... 85 2e-15 UniRef50_Q8YCL4 Cluster: 3-OXOACYL-(ACYL-CARRIER PROTEIN) REDUCT... 85 2e-15 UniRef50_Q82GU5 Cluster: Putative dehydrogenase; n=1; Streptomyc... 85 2e-15 UniRef50_Q1YP86 Cluster: Oxidoreductase; n=2; unclassified Gamma... 85 2e-15 UniRef50_Q0K3J3 Cluster: Short chain dehydrogenase; n=2; Cupriav... 85 2e-15 UniRef50_Q62GY7 Cluster: Oxidoreductase, short-chain dehydrogena... 84 3e-15 UniRef50_Q0B254 Cluster: Short-chain dehydrogenase/reductase SDR... 84 3e-15 UniRef50_A0Z2D1 Cluster: Short-chain dehydrogenase/reductase (SD... 84 3e-15 UniRef50_A0TW00 Cluster: Short-chain dehydrogenase/reductase SDR... 84 3e-15 UniRef50_Q6C6W8 Cluster: Similar to tr|Q9WYD3 Thermotoga maritim... 84 3e-15 UniRef50_A3CUL1 Cluster: Short-chain dehydrogenase/reductase SDR... 84 3e-15 UniRef50_Q3IE74 Cluster: 2O-beta-hydroxysteroid dehydrogenase; n... 84 4e-15 UniRef50_Q390G9 Cluster: Short-chain dehydrogenase/reductase SDR... 84 4e-15 UniRef50_Q0LUS2 Cluster: Short-chain dehydrogenase/reductase SDR... 84 4e-15 UniRef50_A5V529 Cluster: Short-chain dehydrogenase/reductase SDR... 84 4e-15 UniRef50_A3XKE6 Cluster: Short-chain dehydrogenase/reductase SDR... 84 4e-15 UniRef50_Q8U3B3 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 84 4e-15 UniRef50_P69166 Cluster: 3-alpha-(or 20-beta)-hydroxysteroid deh... 84 4e-15 UniRef50_Q9A3M7 Cluster: Short chain dehydrogenase family protei... 83 5e-15 UniRef50_Q8EMX3 Cluster: Hypothetical conserved protein; n=1; Oc... 83 5e-15 UniRef50_Q5YUD9 Cluster: Putative short chain dehydrogenase; n=1... 83 5e-15 UniRef50_Q12HD3 Cluster: Short-chain dehydrogenase/reductase SDR... 83 5e-15 UniRef50_Q0SJP8 Cluster: Short chain dehydrogenase; n=1; Rhodoco... 83 5e-15 UniRef50_Q0LZB7 Cluster: NAD-dependent epimerase/dehydratase:Sho... 83 5e-15 UniRef50_Q0LPB7 Cluster: Short-chain dehydrogenase/reductase SDR... 83 5e-15 UniRef50_A1K1F4 Cluster: Short-chain dehydrogenase family protei... 83 5e-15 UniRef50_A1CYI4 Cluster: Short chain dehydrogenase/reductase fam... 83 5e-15 UniRef50_A3HAH4 Cluster: Short-chain dehydrogenase/reductase SDR... 83 5e-15 UniRef50_A2BJK2 Cluster: Short chain dehydrogenase; n=1; Hyperth... 83 5e-15 UniRef50_Q7W7A0 Cluster: Probable 3-oxoacyl-[acyl-carrier protei... 83 7e-15 UniRef50_Q7W2M6 Cluster: Alcohol dehydrogenase; n=15; cellular o... 83 7e-15 UniRef50_Q46NM9 Cluster: Short-chain dehydrogenase/reductase SDR... 83 7e-15 UniRef50_Q39TI0 Cluster: Short-chain dehydrogenase/reductase SDR... 83 7e-15 UniRef50_Q396N3 Cluster: Short-chain dehydrogenase/reductase SDR... 83 7e-15 UniRef50_Q2RUY0 Cluster: Short-chain dehydrogenase/reductase SDR... 83 7e-15 UniRef50_Q0VQZ0 Cluster: Oxidoreductase; n=4; Gammaproteobacteri... 83 7e-15 UniRef50_A4XED1 Cluster: Short-chain dehydrogenase/reductase SDR... 83 7e-15 UniRef50_A1UD58 Cluster: Short-chain dehydrogenase/reductase SDR... 83 7e-15 UniRef50_Q0D3U7 Cluster: Os07g0665000 protein; n=18; Poales|Rep:... 83 7e-15 UniRef50_P76633 Cluster: Uncharacterized oxidoreductase ygcW; n=... 83 7e-15 UniRef50_Q815Q8 Cluster: Short chain dehydrogenase; n=1; Bacillu... 83 9e-15 UniRef50_Q7VV50 Cluster: Probable short chain dehydrogenase; n=1... 83 9e-15 UniRef50_A6C1M0 Cluster: Short chain dehydrogenase; n=1; Plancto... 83 9e-15 UniRef50_A5V1Y0 Cluster: Short-chain dehydrogenase/reductase SDR... 83 9e-15 UniRef50_Q8EPA2 Cluster: Hypothetical conserved protein; n=1; Oc... 82 1e-14 UniRef50_Q5P8S7 Cluster: Cyclohexanol dehydrogenase; n=3; Bacter... 82 1e-14 UniRef50_Q83ZE7 Cluster: Short-chain dehydrogenase/redutase; n=1... 82 1e-14 UniRef50_Q0SK66 Cluster: Short chain dehydrogenase; n=5; Bacteri... 82 1e-14 UniRef50_Q0RYT4 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 82 1e-14 UniRef50_A4RFU8 Cluster: Putative uncharacterized protein; n=1; ... 82 1e-14 UniRef50_Q3IU31 Cluster: Probable dehydrogenase/ reductase 4; n=... 82 1e-14 UniRef50_Q9KQH7 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 82 1e-14 UniRef50_P39071 Cluster: 2,3-dihydro-2,3-dihydroxybenzoate dehyd... 82 1e-14 UniRef50_Q97M39 Cluster: 2 deoxy-D-gluconate 3-dehydrogenase; n=... 82 2e-14 UniRef50_Q883G7 Cluster: Oxidoreductase, short chain dehydrogena... 82 2e-14 UniRef50_Q1ARM4 Cluster: Short-chain dehydrogenase/reductase SDR... 82 2e-14 UniRef50_Q11C03 Cluster: Short-chain dehydrogenase/reductase SDR... 82 2e-14 UniRef50_A7IMM1 Cluster: Short-chain dehydrogenase/reductase SDR... 82 2e-14 UniRef50_A7IEE4 Cluster: Short-chain dehydrogenase/reductase SDR... 82 2e-14 UniRef50_A5WHV5 Cluster: Short-chain dehydrogenase/reductase SDR... 82 2e-14 UniRef50_A5GRS5 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 82 2e-14 UniRef50_A5FRC2 Cluster: Short-chain dehydrogenase/reductase SDR... 82 2e-14 UniRef50_A0PSE4 Cluster: Short-chain type dehydrogenase; n=12; C... 82 2e-14 UniRef50_Q0D3V4 Cluster: Os07g0664000 protein; n=34; cellular or... 82 2e-14 UniRef50_Q9Z8P2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 82 2e-14 UniRef50_Q8YVT0 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 81 2e-14 UniRef50_Q7NFL8 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 81 2e-14 UniRef50_Q3WB10 Cluster: Short-chain dehydrogenase/reductase SDR... 81 2e-14 UniRef50_Q160J4 Cluster: Oxidoreductase, putative; n=2; Alphapro... 81 2e-14 UniRef50_Q0SU93 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n... 81 2e-14 UniRef50_Q0S4U3 Cluster: Dehydrogenase; n=2; Actinomycetales|Rep... 81 2e-14 UniRef50_A5WE64 Cluster: Short-chain dehydrogenase/reductase SDR... 81 2e-14 UniRef50_A5UY97 Cluster: Short-chain dehydrogenase/reductase SDR... 81 2e-14 UniRef50_A4X846 Cluster: Short-chain dehydrogenase/reductase SDR... 81 2e-14 UniRef50_Q5KMV5 Cluster: Fatty acid beta-oxidation-related prote... 81 2e-14 UniRef50_Q97CM7 Cluster: Glucose 1-dehydrogenase; n=6; Archaea|R... 81 2e-14 UniRef50_P00334 Cluster: Alcohol dehydrogenase; n=485; Drosophil... 81 2e-14 UniRef50_Q5KW73 Cluster: 3-ketoacyl-[acyl carrier protein] reduc... 81 3e-14 UniRef50_Q390H0 Cluster: Short-chain dehydrogenase/reductase SDR... 81 3e-14 UniRef50_Q3E3J6 Cluster: Short-chain dehydrogenase/reductase SDR... 81 3e-14 UniRef50_Q1YS84 Cluster: Short-chain dehydrogenase/reductase SDR... 81 3e-14 UniRef50_Q1IU02 Cluster: Short-chain dehydrogenase/reductase SDR... 81 3e-14 UniRef50_Q1AYL3 Cluster: Short-chain dehydrogenase/reductase SDR... 81 3e-14 UniRef50_A5IGZ5 Cluster: Acetyoacetyl CoA reductase; n=4; Legion... 81 3e-14 UniRef50_A3VC22 Cluster: Short-chain dehydrogenase/reductase SDR... 81 3e-14 UniRef50_A0YCW9 Cluster: Putative 3-oxoacyl-acyl carrier protein... 81 3e-14 UniRef50_A0K0G6 Cluster: Short-chain dehydrogenase/reductase SDR... 81 3e-14 UniRef50_A0CAG3 Cluster: Chromosome undetermined scaffold_161, w... 81 3e-14 UniRef50_Q9A322 Cluster: D-beta-hydroxybutyrate dehydrogenase; n... 81 4e-14 UniRef50_Q55922 Cluster: Slr0315 protein; n=2; Bacteria|Rep: Slr... 81 4e-14 UniRef50_Q2JF82 Cluster: Short-chain dehydrogenase/reductase SDR... 81 4e-14 UniRef50_Q11ZZ1 Cluster: Short-chain dehydrogenase/reductase SDR... 81 4e-14 UniRef50_A5UT09 Cluster: Short-chain dehydrogenase/reductase SDR... 81 4e-14 UniRef50_A0YD08 Cluster: Short chain dehydrogenase; n=2; Gammapr... 81 4e-14 UniRef50_Q2UB90 Cluster: Dehydrogenases with different specifici... 81 4e-14 UniRef50_Q3MGE9 Cluster: Short-chain dehydrogenase/reductase SDR... 80 5e-14 UniRef50_Q0SC53 Cluster: Dehydrogenase; n=3; Corynebacterineae|R... 80 5e-14 UniRef50_Q52JK0 Cluster: PhaB; n=16; Bacteria|Rep: PhaB - Bacill... 80 5e-14 UniRef50_Q1AY52 Cluster: Short-chain dehydrogenase/reductase SDR... 80 5e-14 UniRef50_Q0RV59 Cluster: Probable 3-oxoacyl-[acyl-carrier-protei... 80 5e-14 UniRef50_A6GFU2 Cluster: Short chain dehydrogenase; n=1; Plesioc... 80 5e-14 UniRef50_A1B0V7 Cluster: Short-chain dehydrogenase/reductase SDR... 80 5e-14 UniRef50_A0YH24 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; m... 80 5e-14 UniRef50_A1DKR3 Cluster: Short chain dehydrogenase/reductase fam... 80 5e-14 UniRef50_A7DQK3 Cluster: Short-chain dehydrogenase/reductase SDR... 80 5e-14 UniRef50_P14802 Cluster: Uncharacterized oxidoreductase yoxD; n=... 80 5e-14 UniRef50_Q9F5J1 Cluster: SimJ1; n=5; Actinomycetales|Rep: SimJ1 ... 80 7e-14 UniRef50_A5UYE2 Cluster: Short-chain dehydrogenase/reductase SDR... 80 7e-14 UniRef50_A4E7X7 Cluster: Putative uncharacterized protein; n=2; ... 80 7e-14 UniRef50_A0LJK6 Cluster: Short-chain dehydrogenase/reductase SDR... 80 7e-14 UniRef50_Q94G10 Cluster: CTA; n=3; Cucumis sativus|Rep: CTA - Cu... 80 7e-14 UniRef50_A6XGT9 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct... 80 7e-14 UniRef50_P0A2D1 Cluster: Oxidoreductase ucpA; n=21; Bacteria|Rep... 80 7e-14 UniRef50_Q9KA03 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 79 9e-14 UniRef50_Q3W9M4 Cluster: Short-chain dehydrogenase/reductase SDR... 79 9e-14 UniRef50_Q1YPA9 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putati... 79 9e-14 UniRef50_Q1V2Q8 Cluster: Short chain dehydrogenase; n=2; Candida... 79 9e-14 UniRef50_Q13I70 Cluster: Putative short-chain dehydrogenase/redu... 79 9e-14 UniRef50_Q0RJX7 Cluster: Putative 3-oxoacyl-[acyl-carrier protei... 79 9e-14 UniRef50_A4XEH1 Cluster: Short-chain dehydrogenase/reductase SDR... 79 9e-14 UniRef50_A4E921 Cluster: Putative uncharacterized protein; n=1; ... 79 9e-14 UniRef50_Q9LW35 Cluster: Alcohol dehydrogenase-like protein; n=6... 79 9e-14 UniRef50_Q4P1P4 Cluster: Putative uncharacterized protein; n=1; ... 79 9e-14 UniRef50_Q2TXU8 Cluster: Predicted protein; n=2; Aspergillus|Rep... 79 9e-14 UniRef50_Q0UYC7 Cluster: Putative uncharacterized protein; n=1; ... 79 9e-14 UniRef50_A2R8C3 Cluster: Catalytic activity: C. testosteroni bph... 79 9e-14 UniRef50_UPI00015B572E Cluster: PREDICTED: similar to putative a... 79 1e-13 UniRef50_Q9RH24 Cluster: Putative uncharacterized protein; n=1; ... 79 1e-13 UniRef50_Q8YD94 Cluster: TOLUENESULFONATE ZINC-INDEPENDENT ALCOH... 79 1e-13 UniRef50_Q890G1 Cluster: Short-chain dehydrogenase/oxidoreductas... 79 1e-13 UniRef50_Q3BBM8 Cluster: Xylitol dehydrogenase; n=1; Pantoea ana... 79 1e-13 UniRef50_Q1GUT7 Cluster: Short-chain dehydrogenase/reductase SDR... 79 1e-13 UniRef50_A7CX22 Cluster: Short-chain dehydrogenase/reductase SDR... 79 1e-13 UniRef50_A6M088 Cluster: Short-chain dehydrogenase/reductase SDR... 79 1e-13 UniRef50_A5P2C8 Cluster: Short-chain dehydrogenase/reductase SDR... 79 1e-13 UniRef50_A4GHX2 Cluster: Short-chain dehydrogenase/reductase; n=... 79 1e-13 UniRef50_A3U137 Cluster: Short-chain dehydrogenase/reductase SDR... 79 1e-13 UniRef50_A3JWC2 Cluster: Dehydrogenase; n=1; Rhodobacterales bac... 79 1e-13 UniRef50_A2U5Y6 Cluster: Short-chain dehydrogenase/reductase SDR... 79 1e-13 UniRef50_Q97WD7 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 79 1e-13 UniRef50_P91615 Cluster: Alcohol dehydrogenase-related 31 kDa pr... 79 1e-13 UniRef50_UPI000050F7E5 Cluster: COG1028: Dehydrogenases with dif... 79 2e-13 UniRef50_Q62CL0 Cluster: D-beta-hydroxybutyrate dehydrogenase; n... 79 2e-13 UniRef50_Q398I5 Cluster: Short-chain dehydrogenase/reductase SDR... 79 2e-13 UniRef50_Q70I08 Cluster: Putative ketoreductase; n=1; Streptomyc... 79 2e-13 UniRef50_Q1ASH3 Cluster: Short-chain dehydrogenase/reductase SDR... 79 2e-13 UniRef50_Q0LC46 Cluster: Short-chain dehydrogenase/reductase SDR... 79 2e-13 UniRef50_Q0C3P2 Cluster: Oxidoreductase, short chain dehydrogena... 79 2e-13 UniRef50_A6W9E2 Cluster: Short-chain dehydrogenase/reductase SDR... 79 2e-13 UniRef50_A6GTP4 Cluster: 3-ketoacyl-(Acyl-carrier-protein) reduc... 79 2e-13 UniRef50_A4XEV6 Cluster: Short-chain dehydrogenase/reductase SDR... 79 2e-13 UniRef50_A1SKK7 Cluster: Short-chain dehydrogenase/reductase SDR... 79 2e-13 UniRef50_A0YA77 Cluster: Short-chain dehydrogenase/reductase; n=... 79 2e-13 UniRef50_A0VT49 Cluster: Short-chain dehydrogenase/reductase SDR... 79 2e-13 UniRef50_A0V892 Cluster: Short-chain dehydrogenase/reductase SDR... 79 2e-13 UniRef50_A0QZR1 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=... 79 2e-13 UniRef50_A0QV78 Cluster: Cyclopentanol dehydrogenase; n=2; Bacte... 79 2e-13 UniRef50_A0QH10 Cluster: Short-chain dehydrogenase/reductase SDR... 79 2e-13 UniRef50_A0KYX3 Cluster: Short-chain dehydrogenase/reductase SDR... 79 2e-13 UniRef50_Q5UYZ8 Cluster: Glucose dehydrogenase; n=5; Halobacteri... 79 2e-13 UniRef50_A5UJ48 Cluster: Short chain dehydrogenase; n=1; Methano... 79 2e-13 UniRef50_Q87GW0 Cluster: Acetoacetyl-CoA reductase; n=7; Vibrio|... 78 2e-13 UniRef50_Q2VQT1 Cluster: Ketoacyl ACP/CoA reductase-like protein... 78 2e-13 UniRef50_Q216Y0 Cluster: 3-hydroxybutyrate dehydrogenase precurs... 78 2e-13 UniRef50_Q1GNJ2 Cluster: Short-chain dehydrogenase/reductase SDR... 78 2e-13 UniRef50_Q0FWE7 Cluster: Short-chain alcohol dehydrogenase; n=2;... 78 2e-13 UniRef50_Q03U43 Cluster: Short-chain alcohol dehydrogenase; n=4;... 78 2e-13 UniRef50_A1T7K9 Cluster: Short-chain dehydrogenase/reductase SDR... 78 2e-13 UniRef50_A0L0X0 Cluster: Short-chain dehydrogenase/reductase SDR... 78 2e-13 UniRef50_Q4WR19 Cluster: Short chain dehydrogenase, putative; n=... 78 2e-13 UniRef50_Q92EK7 Cluster: Uncharacterized oxidoreductase Lin0452;... 78 2e-13 UniRef50_P50842 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=... 78 2e-13 UniRef50_Q48436 Cluster: Acetoin(diacetyl) reductase; n=59; cell... 78 2e-13 UniRef50_Q4RS15 Cluster: Chromosome 7 SCAF15001, whole genome sh... 62 2e-13 UniRef50_UPI0000E480C6 Cluster: PREDICTED: similar to short-chai... 78 3e-13 UniRef50_UPI00004996DD Cluster: 3-oxoacyl-(acyl-carrier protein)... 78 3e-13 UniRef50_Q9KBT2 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 78 3e-13 UniRef50_Q7NCW8 Cluster: Gll2858 protein; n=6; Bacteria|Rep: Gll... 78 3e-13 UniRef50_Q6N3Z1 Cluster: Putative oxidoreductase, short-chain de... 78 3e-13 UniRef50_Q65SP1 Cluster: FabG protein; n=10; Bacteria|Rep: FabG ... 78 3e-13 UniRef50_Q2G8A5 Cluster: Short-chain dehydrogenase/reductase SDR... 78 3e-13 UniRef50_Q2G822 Cluster: Short-chain dehydrogenase/reductase SDR... 78 3e-13 UniRef50_Q3WFP9 Cluster: Short-chain dehydrogenase/reductase SDR... 78 3e-13 UniRef50_Q3WCZ4 Cluster: Short-chain dehydrogenase/reductase SDR... 78 3e-13 UniRef50_Q128N5 Cluster: Short-chain dehydrogenase/reductase SDR... 78 3e-13 UniRef50_Q03TH6 Cluster: 3-oxoacyl-acyl carrier protein reductas... 78 3e-13 UniRef50_A6GC41 Cluster: Short-chain dehydrogenase/reductase SDR... 78 3e-13 UniRef50_A5WXW8 Cluster: MocC; n=2; Agrobacterium tumefaciens|Re... 78 3e-13 UniRef50_A3TMC1 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 78 3e-13 UniRef50_A1SHT3 Cluster: Short-chain dehydrogenase/reductase SDR... 78 3e-13 UniRef50_O82465 Cluster: Short-chain alcohol dehydrogenase; n=11... 78 3e-13 UniRef50_Q54PT0 Cluster: Putative uncharacterized protein; n=1; ... 78 3e-13 UniRef50_Q6BVQ9 Cluster: Debaryomyces hansenii chromosome C of s... 78 3e-13 UniRef50_A7DSF0 Cluster: Short-chain dehydrogenase/reductase SDR... 78 3e-13 UniRef50_P46331 Cluster: Uncharacterized oxidoreductase yxbG; n=... 78 3e-13 UniRef50_Q9C826 Cluster: Xanthoxin dehydrogenase; n=41; Magnolio... 78 3e-13 UniRef50_Q5BLE6 Cluster: Zgc:113054; n=8; Euteleostomi|Rep: Zgc:... 77 4e-13 UniRef50_Q7WAF7 Cluster: Putative oxidoreductase; n=3; Bordetell... 77 4e-13 UniRef50_Q2S7V4 Cluster: Short-chain alcohol dehydrogenase-like ... 77 4e-13 UniRef50_Q2GAH3 Cluster: Short-chain dehydrogenase/reductase SDR... 77 4e-13 UniRef50_Q2G758 Cluster: Short-chain dehydrogenase/reductase SDR... 77 4e-13 UniRef50_Q1YQ07 Cluster: Putative uncharacterized protein; n=1; ... 77 4e-13 UniRef50_Q0SJT0 Cluster: Short chain dehydrogenase; n=13; Actino... 77 4e-13 UniRef50_Q0FK50 Cluster: Putative uncharacterized protein; n=1; ... 77 4e-13 UniRef50_A4CNY9 Cluster: Oxidoreductase, short chain dehydrogena... 77 4e-13 UniRef50_A3ZNA3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 77 4e-13 UniRef50_A2WII1 Cluster: Short-chain alcohol dehydrogenase; n=8;... 77 4e-13 UniRef50_A1SMM6 Cluster: Short-chain dehydrogenase/reductase SDR... 77 4e-13 UniRef50_A0Z215 Cluster: Short chain dehydrogenase; n=2; Gammapr... 77 4e-13 UniRef50_A0KRX7 Cluster: Short-chain dehydrogenase/reductase SDR... 77 4e-13 UniRef50_A2QS57 Cluster: Contig An08c0220, complete genome; n=2;... 77 4e-13 UniRef50_A1DKS5 Cluster: Short chain dehydrogenase/reductase fam... 77 4e-13 UniRef50_A0RXB6 Cluster: Short-chain alcohol dehydrogenase; n=2;... 77 4e-13 UniRef50_P00335 Cluster: Ribitol 2-dehydrogenase; n=5; Proteobac... 77 4e-13 UniRef50_Q71R50 Cluster: Dehydrogenase/reductase SDR family memb... 77 4e-13 UniRef50_Q89W00 Cluster: Blr0893 protein; n=7; Bradyrhizobiaceae... 77 5e-13 UniRef50_Q81RT0 Cluster: Oxidoreductase, short-chain dehydrogena... 77 5e-13 UniRef50_Q6NDJ6 Cluster: Putative 3-oxoacyl-(Acyl carrier ptn) r... 77 5e-13 UniRef50_Q39TG1 Cluster: Short-chain dehydrogenase/reductase SDR... 77 5e-13 UniRef50_Q2W431 Cluster: Dehydrogenase with different specificit... 77 5e-13 UniRef50_Q1BF92 Cluster: Short-chain dehydrogenase/reductase SDR... 77 5e-13 UniRef50_Q0SJS1 Cluster: Short chain dehydrogenase/reductase; n=... 77 5e-13 UniRef50_Q0SGL6 Cluster: Short chain dehydrogenase; n=6; Actinom... 77 5e-13 UniRef50_Q0S716 Cluster: Short chain dehydrogenase; n=3; Bacteri... 77 5e-13 UniRef50_Q0S5L2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 77 5e-13 UniRef50_A6UFI1 Cluster: Short-chain dehydrogenase/reductase SDR... 77 5e-13 UniRef50_A3K9R7 Cluster: Sorbitol dehydrogenase; n=4; Proteobact... 77 5e-13 UniRef50_A1WNV5 Cluster: Short-chain dehydrogenase/reductase SDR... 77 5e-13 UniRef50_A1UA98 Cluster: Short-chain dehydrogenase/reductase SDR... 77 5e-13 UniRef50_A2YPN0 Cluster: Putative uncharacterized protein; n=3; ... 77 5e-13 UniRef50_Q4PI07 Cluster: Putative uncharacterized protein; n=1; ... 77 5e-13 UniRef50_Q8TUG0 Cluster: Gluconate 5-dehydrogenase; n=7; cellula... 77 5e-13 UniRef50_UPI0000E465C5 Cluster: PREDICTED: similar to MGC80593 p... 77 6e-13 UniRef50_Q9L2C9 Cluster: Putative dehydrogenase; n=2; Streptomyc... 77 6e-13 UniRef50_Q6MLN8 Cluster: Oxidoreductase; n=1; Bdellovibrio bacte... 77 6e-13 UniRef50_Q39MU4 Cluster: Short-chain dehydrogenase/reductase SDR... 77 6e-13 UniRef50_Q3WCH3 Cluster: Short-chain dehydrogenase/reductase SDR... 77 6e-13 UniRef50_Q1N1P3 Cluster: Alcohol dehydrogenase; n=1; Oceanobacte... 77 6e-13 UniRef50_Q143W5 Cluster: Putative dehydrogenase; n=1; Burkholder... 77 6e-13 UniRef50_O84991 Cluster: Putative short-chain dehydrogenase/redu... 77 6e-13 UniRef50_A4VH60 Cluster: 3-hydroxyacyl-CoA dehydrogenase FadB2x;... 77 6e-13 UniRef50_A0XX22 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 77 6e-13 UniRef50_A0UZI2 Cluster: Short-chain dehydrogenase/reductase SDR... 77 6e-13 UniRef50_A0PLX0 Cluster: Carveol-like dehydrogenase; n=1; Mycoba... 77 6e-13 UniRef50_A0NRY8 Cluster: Short-chain dehydrogenase/reductase SDR... 77 6e-13 UniRef50_Q21481 Cluster: Dehydrogenases, short chain protein 28;... 77 6e-13 UniRef50_Q9HSR4 Cluster: Oxidoreductase; n=6; cellular organisms... 77 6e-13 UniRef50_Q5V0V4 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 77 6e-13 UniRef50_P50198 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 77 6e-13 UniRef50_Q9AK65 Cluster: Putative glucose 1-dehydrogenase; n=2; ... 76 8e-13 UniRef50_Q88SD1 Cluster: Short-chain dehydrogenase/oxidoreductas... 76 8e-13 UniRef50_Q1YS63 Cluster: Putative dehydrogenase; n=1; gamma prot... 76 8e-13 UniRef50_Q1NH63 Cluster: Dehydrogenase; n=1; Sphingomonas sp. SK... 76 8e-13 UniRef50_Q0FWE6 Cluster: Putative oxidoreductase; n=1; Roseovari... 76 8e-13 UniRef50_Q08MV7 Cluster: D-beta-hydroxybutyrate dehydrogenase; n... 76 8e-13 UniRef50_Q03906 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n... 76 8e-13 UniRef50_Q023X9 Cluster: Short-chain dehydrogenase/reductase SDR... 76 8e-13 UniRef50_A4XF74 Cluster: Short-chain dehydrogenase/reductase SDR... 76 8e-13 UniRef50_A0ZL93 Cluster: Short-chain dehydrogenase/reductase SDR... 76 8e-13 UniRef50_A0R7C5 Cluster: Oxidoreductase; n=3; Mycobacterium smeg... 76 8e-13 UniRef50_A0QZE2 Cluster: Short chain dehydrogenase; n=1; Mycobac... 76 8e-13 UniRef50_A0J9Z3 Cluster: Short-chain dehydrogenase/reductase SDR... 76 8e-13 UniRef50_A0GPG2 Cluster: Short-chain dehydrogenase/reductase SDR... 76 8e-13 UniRef50_Q9VQ39 Cluster: CG31937-PA; n=3; Sophophora|Rep: CG3193... 76 8e-13 UniRef50_P19992 Cluster: 3-alpha-(or 20-beta)-hydroxysteroid deh... 76 8e-13 UniRef50_Q9KEC1 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 76 1e-12 UniRef50_Q9ABX6 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 76 1e-12 UniRef50_Q9ABI1 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 76 1e-12 UniRef50_Q93QG5 Cluster: Cyclohexanol dehydrogenase; n=4; Bacter... 76 1e-12 UniRef50_Q3WGR0 Cluster: Short-chain dehydrogenase/reductase SDR... 76 1e-12 UniRef50_Q1B6I2 Cluster: Short-chain dehydrogenase/reductase SDR... 76 1e-12 UniRef50_A6VSM3 Cluster: Short-chain dehydrogenase/reductase SDR... 76 1e-12 UniRef50_A5VBH4 Cluster: Short-chain dehydrogenase/reductase SDR... 76 1e-12 UniRef50_A5V382 Cluster: Short-chain dehydrogenase/reductase SDR... 76 1e-12 UniRef50_A4F720 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 76 1e-12 UniRef50_A1VQT6 Cluster: Short-chain dehydrogenase/reductase SDR... 76 1e-12 UniRef50_A1SPQ9 Cluster: Short-chain dehydrogenase/reductase SDR... 76 1e-12 UniRef50_A1IBD2 Cluster: Putative oxidoreductase protein, short-... 76 1e-12 UniRef50_A1BEI9 Cluster: Short-chain dehydrogenase/reductase SDR... 76 1e-12 UniRef50_A1B7W8 Cluster: Short-chain dehydrogenase/reductase SDR... 76 1e-12 UniRef50_A0QMR9 Cluster: Oxidoreductase, short chain dehydrogena... 76 1e-12 UniRef50_Q5KIP0 Cluster: Oxidoreductase, putative; n=2; Basidiom... 76 1e-12 UniRef50_A3H6D0 Cluster: Short-chain dehydrogenase/reductase SDR... 76 1e-12 UniRef50_Q98C97 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 75 1e-12 UniRef50_Q988J7 Cluster: Oxidoreductase, short chain dehydrogena... 75 1e-12 UniRef50_Q93HC0 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 75 1e-12 UniRef50_Q89D37 Cluster: Oxidoreductase; n=6; Alphaproteobacteri... 75 1e-12 UniRef50_Q3KCL1 Cluster: Short-chain dehydrogenase/reductase SDR... 75 1e-12 UniRef50_Q5KRC1 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 75 1e-12 UniRef50_Q3W0V5 Cluster: Short-chain dehydrogenase/reductase SDR... 75 1e-12 UniRef50_A7HL35 Cluster: Short-chain dehydrogenase/reductase SDR... 75 1e-12 UniRef50_A4AA34 Cluster: Short-chain dehydrogenase/reductase SDR... 75 1e-12 UniRef50_A3WIC9 Cluster: Oxidoreductase, short chain dehydrogena... 75 1e-12 UniRef50_A3I824 Cluster: Short-chain dehydrogenase/reductase SDR... 75 1e-12 UniRef50_A1SNF3 Cluster: Short-chain dehydrogenase/reductase SDR... 75 1e-12 UniRef50_A1SC90 Cluster: Short-chain dehydrogenase/reductase SDR... 75 1e-12 UniRef50_A0QII3 Cluster: Oxidoreductase, short chain dehydrogena... 75 1e-12 UniRef50_A7Q0U9 Cluster: Chromosome chr7 scaffold_42, whole geno... 75 1e-12 UniRef50_Q54D03 Cluster: Putative uncharacterized protein; n=1; ... 75 1e-12 UniRef50_Q2U8E2 Cluster: Dehydrogenases with different specifici... 75 1e-12 UniRef50_Q0UYC9 Cluster: Putative uncharacterized protein; n=1; ... 75 1e-12 UniRef50_Q0UEE2 Cluster: Putative uncharacterized protein; n=1; ... 75 1e-12 UniRef50_A7ELQ5 Cluster: Putative uncharacterized protein; n=1; ... 75 1e-12 UniRef50_P55541 Cluster: Uncharacterized short-chain type dehydr... 75 1e-12 UniRef50_Q8EMP9 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 75 2e-12 UniRef50_Q89M15 Cluster: Dehydrogenase; n=3; Proteobacteria|Rep:... 75 2e-12 UniRef50_Q7WBP3 Cluster: Probable short chain dehydrogenase; n=2... 75 2e-12 UniRef50_Q5LQS9 Cluster: Oxidoreductase, short chain dehydrogena... 75 2e-12 UniRef50_Q39N51 Cluster: Short-chain dehydrogenase/reductase SDR... 75 2e-12 UniRef50_Q3WJ90 Cluster: Short-chain dehydrogenase/reductase SDR... 75 2e-12 UniRef50_Q1ILJ4 Cluster: Short-chain dehydrogenase/reductase SDR... 75 2e-12 UniRef50_Q1ARQ7 Cluster: Short-chain dehydrogenase/reductase SDR... 75 2e-12 UniRef50_Q03X86 Cluster: Putative uncharacterized protein; n=1; ... 75 2e-12 UniRef50_Q01XW0 Cluster: Short-chain dehydrogenase/reductase SDR... 75 2e-12 UniRef50_A6F000 Cluster: Putative short-chain dehydrogenase/redu... 75 2e-12 >UniRef50_Q7PY55 Cluster: ENSANGP00000013280; n=4; Endopterygota|Rep: ENSANGP00000013280 - Anopheles gambiae str. PEST Length = 183 Score = 238 bits (582), Expect = 1e-61 Identities = 115/184 (62%), Positives = 135/184 (73%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLF 239 MDLK KVAL+TGAA+G+G A+SEELLK GAKV +CD+DS+ GE E+L +YG + VLF Sbjct: 1 MDLKNKVALVTGAATGLGRAFSEELLKHGAKVVICDLDSDAGELTVEELEKQYGAR-VLF 59 Query: 240 CRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRLWELEVDVNLNGVIRGTLLAYR 419 C DVTDY QFEEAF TV F ++IVINNA MND WELEVDVNLNG IRGTLLA + Sbjct: 60 CHCDVTDYIQFEEAFEYTVNMFKEVNIVINNAEIMNDNFWELEVDVNLNGAIRGTLLAQK 119 Query: 420 FMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTGVRCLV 599 FM K +G GGV+VN S PQ+STPIYTAT +AI+GLT+A GD +H T VR Sbjct: 120 FMDKSKGKGGGVLVNIGSGVSVTPQLSTPIYTATKHAILGLTKACGDPFHHANTNVRAFA 179 Query: 600 VCPG 611 CPG Sbjct: 180 YCPG 183 >UniRef50_Q6RUR3 Cluster: Putative alcohol dehydrogenase; n=2; Neoptera|Rep: Putative alcohol dehydrogenase - Gryllotalpa orientalis (Oriental mole cricket) Length = 266 Score = 190 bits (463), Expect = 3e-47 Identities = 87/194 (44%), Positives = 128/194 (65%), Gaps = 1/194 (0%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAK-VSLCDIDSERGEQVTEKLASKYGRKNVL 236 MD KGK AL+TG A+GIGLAY +ELL+ G + V++ D+D +G+ ++L ++G + Sbjct: 1 MDPKGKYALVTGGATGIGLAYVKELLRHGVQAVAVADLDERKGDNSVKQLNDEFGAGKAI 60 Query: 237 FCRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRLWELEVDVNLNGVIRGTLLAY 416 F + DVT+ E F F +DIVINNAG ++D WE E+ +N+ V RGT LA+ Sbjct: 61 FIKCDVTNKDDLEATFRKAAATFKGLDIVINNAGILDDSRWETEIAINVTAVARGTWLAF 120 Query: 417 RFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTGVRCL 596 MGK++GG+GGV+VN AS + P+Y AT +A+VGL+R++G YH + TGVR L Sbjct: 121 DLMGKNKGGRGGVVVNIASILGLQAMAGCPVYVATKHAVVGLSRSFGMPYHFDRTGVRVL 180 Query: 597 VVCPGLTDSGLVXD 638 +CPG+TD+ L+ + Sbjct: 181 TMCPGVTDTPLISE 194 >UniRef50_UPI0000D57363 Cluster: PREDICTED: similar to hydroxyprostaglandin dehydrogenase 15 (NAD); n=2; Tribolium castaneum|Rep: PREDICTED: similar to hydroxyprostaglandin dehydrogenase 15 (NAD) - Tribolium castaneum Length = 479 Score = 179 bits (436), Expect = 6e-44 Identities = 87/231 (37%), Positives = 143/231 (61%), Gaps = 2/231 (0%) Frame = +3 Query: 63 DLKGKVALITGAASGIGLAYSEELLKQGAK-VSLCDIDSERGEQVTEKLASKYGRKNVLF 239 D+ KVALI+GAASGIGL ++ELL+ G + V++ D++ E GE+ +++ +++G +F Sbjct: 4 DINNKVALISGAASGIGLTIAKELLRNGLRGVTIADVNKELGEKALQEIENEFGSGRAIF 63 Query: 240 CRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRLWELEVDVNLNGVIRGTLLAY- 416 DV+ FE+AF T+ F IDI++N AG +ND +W+ E+ +N+NG + G LLA Sbjct: 64 VLTDVSSMKSFEDAFQKTINTFKNIDILVNGAGVLNDSIWQQEIAINVNGTVHGILLALE 123 Query: 417 RFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTGVRCL 596 ++ K + GVIVN +S A + PIYT T +AI G+T+A+GD+ H T VR + Sbjct: 124 NYIPKYKTDSEGVIVNFSSIAGVAAFPAFPIYTGTKFAIFGMTKAFGDEAHYERTKVRIM 183 Query: 597 VVCPGLTDSGLVXDLDKQLMSSKYETAWLEDITDSKCRALITLGKPLVDVL 749 +CPG TD+ L+ D+ + + + YE E + D++ + + + LV ++ Sbjct: 184 AICPGPTDTPLLRDISGRNLGAPYEKLLQELLKDTRGQKPEAVARGLVQIV 234 Score = 140 bits (338), Expect = 4e-32 Identities = 64/173 (36%), Positives = 107/173 (61%), Gaps = 1/173 (0%) Frame = +3 Query: 153 VSLCDIDSERGEQVTEKLASKYGRKNVLFCRLDVTDYPQFEEAFVMTVEEFNRIDIVINN 332 V++ DI++E GE+V +++ +++G+ ++ DVT +E AF T+E F +DIV+N Sbjct: 245 VTIADINTELGEKVLQEIINEFGKNKAIYILTDVTCKNSYEAAFKKTIETFQNLDIVVNG 304 Query: 333 AGFMNDRLWELEVDVNLNGVIRGTLLAY-RFMGKDRGGQGGVIVNTASTAFARPQVSTPI 509 AG +N+ W+ EVD+NLNG + GT+LA ++ K + G GVIVN +S A PI Sbjct: 305 AGIVNELDWQQEVDINLNGTLHGTILALENYIPKYKSGSEGVIVNISSAAILDCFPPYPI 364 Query: 510 YTATNYAIVGLTRAYGDQYHVNVTGVRCLVVCPGLTDSGLVXDLDKQLMSSKY 668 YT T +A++G+++++G + H T VR L CPG+T++ ++ +S Y Sbjct: 365 YTGTKFAVMGISKSFGAEVHYKRTKVRVLTACPGVTETPFGIQASEKCLSEPY 417 >UniRef50_Q6NYE8 Cluster: Zgc:56585 protein; n=5; Clupeocephala|Rep: Zgc:56585 protein - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 270 Score = 169 bits (412), Expect = 5e-41 Identities = 86/213 (40%), Positives = 129/213 (60%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLF 239 MDLK KVA++TGAA G+G ++ E L+K G+KV+L D++ GE++ L +YG F Sbjct: 1 MDLKDKVAVVTGAAQGLGRSFVEILMKNGSKVALIDVNKSLGEELKTNLNKEYGPNRAEF 60 Query: 240 CRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRLWELEVDVNLNGVIRGTLLAYR 419 DV+ F+ VE+F +IDI+ NNAG +N++ WE + +NL GV+RGT LA Sbjct: 61 YTADVSSEEDFKGVLKKIVEQFGQIDIMCNNAGIINEKHWEKTIAINLGGVVRGTYLALE 120 Query: 420 FMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTGVRCLV 599 +M K+ GG GGVIVN AS A P PIYTAT + +VG +RA ++ GVR V Sbjct: 121 YMKKENGGSGGVIVNVASMAGLGPLPVAPIYTATKHGVVGFSRAMAVVSKLSNYGVRINV 180 Query: 600 VCPGLTDSGLVXDLDKQLMSSKYETAWLEDITD 698 +CP + L+ L+ + + + + +++IT+ Sbjct: 181 LCPWFVKTSLLSLLNSEEHTGSF--SQMKEITE 211 >UniRef50_P15428 Cluster: 15-hydroxyprostaglandin dehydrogenase [NAD+]; n=29; Euteleostomi|Rep: 15-hydroxyprostaglandin dehydrogenase [NAD+] - Homo sapiens (Human) Length = 266 Score = 166 bits (404), Expect = 4e-40 Identities = 80/203 (39%), Positives = 121/203 (59%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLF 239 M + GKVAL+TGAA GIG A++E LL +GAKV+L D + E G Q L ++ + LF Sbjct: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 Query: 240 CRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRLWELEVDVNLNGVIRGTLLAYR 419 + DV D Q + F V+ F R+DI++NNAG N++ WE + +NL VI GT L Sbjct: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLGLD 120 Query: 420 FMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTGVRCLV 599 +M K GG+GG+I+N +S A P P+Y A+ + IVG TR+ ++ +GVR Sbjct: 121 YMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNA 180 Query: 600 VCPGLTDSGLVXDLDKQLMSSKY 668 +CPG ++ ++ ++K+ +Y Sbjct: 181 ICPGFVNTAILESIEKEENMGQY 203 >UniRef50_UPI0000D57364 Cluster: PREDICTED: similar to 15-hydroxyprostaglandin dehydrogenase [NAD+] (PGDH) (Prostaglandin dehydrogenase 1); n=1; Tribolium castaneum|Rep: PREDICTED: similar to 15-hydroxyprostaglandin dehydrogenase [NAD+] (PGDH) (Prostaglandin dehydrogenase 1) - Tribolium castaneum Length = 312 Score = 165 bits (401), Expect = 1e-39 Identities = 86/221 (38%), Positives = 128/221 (57%), Gaps = 2/221 (0%) Frame = +3 Query: 33 ARCFYS-SINMDLKGKVALITGAASGIGLAYSEELLKQGAK-VSLCDIDSERGEQVTEKL 206 ++ +YS + L VA+ITG A GIGLA + LK G +++ D E+GE+ ++L Sbjct: 38 SQVYYSLGRTLSLDQNVAIITGGAEGIGLAIARVFLKCGISGLAVADCSKEKGEESIKQL 97 Query: 207 ASKYGRKNVLFCRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRLWELEVDVNLN 386 A ++G VLF D++ F+ F T+ F ++IV+NNAG MND WE +V+ NL+ Sbjct: 98 ACEFGENKVLFFDGDMSQSKAFDRVFKETLNHFENVNIVVNNAGVMNDVNWECQVNTNLS 157 Query: 387 GVIRGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQY 566 G I GTLL ++M K GQGG I+N AS P PI+T T + IVG +RA G+ Sbjct: 158 GTIIGTLLGMQYMSKTSLGQGGTIINVASIMGLIPSSGYPIHTLTQFGIVGFSRAIGNLN 217 Query: 567 HVNVTGVRCLVVCPGLTDSGLVXDLDKQLMSSKYETAWLED 689 H + TGVR +CPGLT++ L+ ++ K+ + E+ Sbjct: 218 HFDRTGVRVTALCPGLTNTKLLKQAPYHAINDKFRKEFKEE 258 >UniRef50_UPI0000D57365 Cluster: PREDICTED: similar to CG4899-PA, isoform A; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG4899-PA, isoform A - Tribolium castaneum Length = 295 Score = 164 bits (399), Expect = 2e-39 Identities = 81/203 (39%), Positives = 120/203 (59%), Gaps = 1/203 (0%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAK-VSLCDIDSERGEQVTEKLASKYGRKNVL 236 +D KVALITG + GIGLA + E+L + +K V+L +D+ +G + L S YGR + Sbjct: 47 IDFNCKVALITGGSDGIGLAVAHEILSENSKNVALIGVDNTKGRESVHALNSTYGRNKAV 106 Query: 237 FCRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRLWELEVDVNLNGVIRGTLLAY 416 F DV Q + F ++EF IDIVIN AG + R WE E+ NL G I TL AY Sbjct: 107 FFNCDVESKVQVNDCFNKVIKEFGSIDIVINAAGVFDGRCWEKEIMTNLVGTIHCTLEAY 166 Query: 417 RFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTGVRCL 596 R M KD G GGVI+N + +P P +A+ + I+GL+R++G + + TGVR + Sbjct: 167 RVMSKDCSGSGGVILNFSGLHGVKPLFPAPTLSASFHGIIGLSRSFGHETNFKTTGVRVV 226 Query: 597 VVCPGLTDSGLVXDLDKQLMSSK 665 +CPG+T++ + D +K+ ++ K Sbjct: 227 TLCPGITNTNFIKDAEKRALNEK 249 >UniRef50_UPI000051334A Cluster: PREDICTED: similar to 15-hydroxyprostaglandin dehydrogenase [NAD+] (PGDH) (Prostaglandin dehydrogenase 1) isoform 1; n=1; Apis mellifera|Rep: PREDICTED: similar to 15-hydroxyprostaglandin dehydrogenase [NAD+] (PGDH) (Prostaglandin dehydrogenase 1) isoform 1 - Apis mellifera Length = 264 Score = 164 bits (399), Expect = 2e-39 Identities = 83/225 (36%), Positives = 134/225 (59%), Gaps = 1/225 (0%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAK-VSLCDIDSERGEQVTEKLASKYGRKNVL 236 M ++GK+A++TG A+GIG + +LL+ GAK V+L D+ GE L +++G+ + Sbjct: 1 MSIEGKIAIVTGGANGIGFCTARKLLRNGAKAVALLDLSDSGGESAAADLNNEFGKDRAI 60 Query: 237 FCRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRLWELEVDVNLNGVIRGTLLAY 416 F DV+ QF+E+F ++ + ++I++N AG M+D WE+ VD+N G++ GT+L Sbjct: 61 FIACDVSKNEQFQESFKKVIDTYETLNILVNIAGIMDDADWEIMVDINYKGIVYGTILGL 120 Query: 417 RFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTGVRCL 596 MGK +GG GG+IVN +S A PIY T YAIVG T++ +++ TG+R L Sbjct: 121 HTMGKYKGGNGGIIVNMSSVAGLEGIPIAPIYGGTQYAIVGFTQSL--KHYYEKTGIRML 178 Query: 597 VVCPGLTDSGLVXDLDKQLMSSKYETAWLEDITDSKCRALITLGK 731 +CPGLT + + + MS+K L D ++ A++T+ K Sbjct: 179 TICPGLTTTAMA----ARFMSTKEHAMDLLD-EETAAMAMVTMQK 218 >UniRef50_UPI0000513348 Cluster: PREDICTED: similar to 15-hydroxyprostaglandin dehydrogenase; n=2; Apis mellifera|Rep: PREDICTED: similar to 15-hydroxyprostaglandin dehydrogenase - Apis mellifera Length = 263 Score = 161 bits (392), Expect = 1e-38 Identities = 79/191 (41%), Positives = 119/191 (62%), Gaps = 1/191 (0%) Frame = +3 Query: 63 DLKGKVALITGAASGIGLAYSEELLKQGAK-VSLCDIDSERGEQVTEKLASKYGRKNVLF 239 ++K K ALITG G+GL Y++ LL+ GAK V+L D+ S G+Q L ++G+ +F Sbjct: 4 NIKNKTALITGGTVGLGLIYAKRLLENGAKCVALLDLSSSPGQQTVNNLEKEFGKGKAIF 63 Query: 240 CRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRLWELEVDVNLNGVIRGTLLAYR 419 DV++ +FE F V + N +DIVINNAG ND+ WE + +N+ GVI+G+LLA+ Sbjct: 64 YACDVSNINEFEAVFKKVVNDLNGLDIVINNAGIYNDKKWEQTMCINVGGVIQGSLLAFD 123 Query: 420 FMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTGVRCLV 599 M K +GG+GG IVN AS S P+Y A+ + ++ +R+ Y N TG+R L+ Sbjct: 124 HMSKLKGGKGGTIVNIASIVALDIIYSNPVYCASKHFVLAFSRSLARYY--NNTGIRILI 181 Query: 600 VCPGLTDSGLV 632 +CPG+T + L+ Sbjct: 182 MCPGVTTTSLL 192 >UniRef50_UPI00015B5317 Cluster: PREDICTED: similar to putative alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to putative alcohol dehydrogenase - Nasonia vitripennis Length = 337 Score = 161 bits (390), Expect = 2e-38 Identities = 79/229 (34%), Positives = 132/229 (57%), Gaps = 1/229 (0%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGA-KVSLCDIDSERGEQVTEKLASKYGRKNVLFC 242 + GK LITG A+G+G A+ L+ GA K+ + DID G+++ +G V+F Sbjct: 43 VSGKNVLITGGAAGLGHAFFNHFLQFGANKICIIDIDDVAGKKIVASTDKSHGVGKVIFI 102 Query: 243 RLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRLWELEVDVNLNGVIRGTLLAYRF 422 DV+ + + F V+ + +DIV+NNAG +++R WE E+ VNLNG+I LL+ ++ Sbjct: 103 HADVSRHSEIVAGFQKAVKLMDAVDIVVNNAGILDERRWEREIAVNLNGMISVALLSMQY 162 Query: 423 MGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTGVRCLVV 602 MG+D GG+GG++VN A P+YTAT AI+GL+++ + TGVR + + Sbjct: 163 MGRDMGGRGGILVNVAEHMDVHCTAQLPVYTATKQAIIGLSQSLAAPCNTERTGVRVITL 222 Query: 603 CPGLTDSGLVXDLDKQLMSSKYETAWLEDITDSKCRALITLGKPLVDVL 749 CPGLT++ L D +L+S + +++++ + + + L+ VL Sbjct: 223 CPGLTETALTIDSPNKLLSRVMKADFVKNLEQLTIQTPYVVAQGLMSVL 271 >UniRef50_UPI00015B5316 Cluster: PREDICTED: similar to putative alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to putative alcohol dehydrogenase - Nasonia vitripennis Length = 329 Score = 159 bits (387), Expect = 5e-38 Identities = 73/198 (36%), Positives = 120/198 (60%), Gaps = 1/198 (0%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQG-AKVSLCDIDSERGEQVTEKLASKYGRKNVL 236 M +K K A++ GA G+G+A+S+ELL+ G A+V + D++ G ++L ++GR Sbjct: 68 MQIKDKKAMVIGACDGLGMAFSKELLRNGVARVLMIDMNETLGRAQADRLNEEFGRNRAT 127 Query: 237 FCRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRLWELEVDVNLNGVIRGTLLAY 416 F + DVT +F+ F V +DI++NNA +++ + +D N+ V R +++ Sbjct: 128 FTKCDVTKGSEFDACFKDAVNTLGALDIIVNNAAMIDEVNFHRTIDTNVTAVFRASMMGV 187 Query: 417 RFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTGVRCL 596 + MGKD GG+GGVIVN AS PIY+ATN+A++ +R++ YH TGVR + Sbjct: 188 QQMGKDTGGKGGVIVNVASVLGLEACPQLPIYSATNHAVIAFSRSFSQPYHYQRTGVRLM 247 Query: 597 VVCPGLTDSGLVXDLDKQ 650 V+CPGLT+S ++ +L + Sbjct: 248 VLCPGLTESPMLENLKNE 265 >UniRef50_UPI0000E47587 Cluster: PREDICTED: similar to 15-hydroxyprostaglandin dehydrogenase (NAD+), partial; n=3; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to 15-hydroxyprostaglandin dehydrogenase (NAD+), partial - Strongylocentrotus purpuratus Length = 298 Score = 155 bits (375), Expect = 1e-36 Identities = 78/198 (39%), Positives = 120/198 (60%), Gaps = 2/198 (1%) Frame = +3 Query: 54 INMDLKGKVALITGAASGIGLAYSEELLKQGAK-VSLCDIDSERGEQVTEKLASKYGRKN 230 I M ++G VALITGAA G G A++EELLK+ + + + D ++ +G+ +L KYG Sbjct: 38 IKMKIQGAVALITGAAEGFGKAFTEELLKRSVRGIGIVDFNAAKGKATETELNKKYGEDK 97 Query: 231 VLFCRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRLWELEVDVNLNGVIRGTLL 410 V F + DV+ Q E+AF T+E + IDIV NNAG ++ WE VDV+L V+RGT L Sbjct: 98 VRFFQCDVSSKDQLEDAFSKTLEHYKGIDIVCNNAGIGDELNWEKTVDVDLVAVMRGTFL 157 Query: 411 AYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHV-NVTGV 587 A ++M K++GG+GG+++N AS A P P Y+A + ++G +RA V N V Sbjct: 158 AKQYMDKNKGGRGGIVINIASMAGLYPMPLAPAYSAAKHGVLGFSRALAIADKVFNPENV 217 Query: 588 RCLVVCPGLTDSGLVXDL 641 R +CP +++ ++ + Sbjct: 218 RLNCLCPSFSETAILQQM 235 Score = 45.6 bits (103), Expect = 0.001 Identities = 21/36 (58%), Positives = 27/36 (75%) Frame = +3 Query: 54 INMDLKGKVALITGAASGIGLAYSEELLKQGAKVSL 161 I M ++G VALITGAA G G A+SEELLK+ A+ + Sbjct: 3 IKMKIQGAVALITGAAEGFGKAFSEELLKRSARFKI 38 >UniRef50_UPI00015B42DD Cluster: PREDICTED: similar to putative alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to putative alcohol dehydrogenase - Nasonia vitripennis Length = 261 Score = 153 bits (371), Expect = 4e-36 Identities = 83/199 (41%), Positives = 121/199 (60%), Gaps = 1/199 (0%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAK-VSLCDIDSERGEQVTEKLASKYGRKNVL 236 MD+ KVA+ITG A GIG A + LL+ G K V+L D+D+ +++ L KYG + L Sbjct: 1 MDINNKVAIITGGAGGIGAAIVKRLLEHGIKLVALFDLDNSNTKKIFMDLQKKYGNRVEL 60 Query: 237 FCRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRLWELEVDVNLNGVIRGTLLAY 416 + DVT+ QFEE F ++ IDI++NNAG +D EL +D+N V+ G+LL Sbjct: 61 Y-PCDVTNKAQFEENFDKVLKTHKTIDILLNNAGIGSDIHTELMIDLNYKAVVLGSLLFI 119 Query: 417 RFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTGVRCL 596 +GK +GG+GG+IVNTAS R P+Y +T +A+V TR QY + TGVR + Sbjct: 120 ERLGKHKGGKGGIIVNTASILGLRNFDCLPVYCSTKHAVVSFTRCLDVQY--DTTGVRVV 177 Query: 597 VVCPGLTDSGLVXDLDKQL 653 +CPG+T++ LV + K + Sbjct: 178 AICPGVTETPLVSSVSKAM 196 >UniRef50_A7SGX6 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 266 Score = 153 bits (370), Expect = 6e-36 Identities = 83/199 (41%), Positives = 114/199 (57%), Gaps = 8/199 (4%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLF 239 M ++G VA++TG GIGLA S+ LL + KV + DI+ + G + + L+ Y + VLF Sbjct: 1 MKIEGTVAIVTGGVQGIGLAISKALLDRDGKVCMLDINEKTGNETLKLLSENYSKHRVLF 60 Query: 240 CRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFM---NDRL----WELEVDVNLNGVIR 398 + DVT PQ E AF T + F R+DI+ NNAG ND L W+ +D+N+ GVI Sbjct: 61 IKCDVTSQPQMEAAFQRTKDVFGRLDILCNNAGIAVRENDLLRSGAWKTIIDINVKGVIL 120 Query: 399 GTLLAYRFMG-KDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVN 575 GTLL MG G GG IVN AS A P ++P+YTA+ +A+VGLTR + Sbjct: 121 GTLLGLDHMGVSGAKGHGGTIVNVASLAGLVPAPASPVYTASKHAVVGLTRTLTSLWATE 180 Query: 576 VTGVRCLVVCPGLTDSGLV 632 V C +CP TD+ +V Sbjct: 181 CVRVNC--ICPSFTDTAMV 197 >UniRef50_UPI0000DB7440 Cluster: PREDICTED: similar to 15-hydroxyprostaglandin dehydrogenase; n=1; Apis mellifera|Rep: PREDICTED: similar to 15-hydroxyprostaglandin dehydrogenase - Apis mellifera Length = 266 Score = 145 bits (351), Expect = 1e-33 Identities = 74/189 (39%), Positives = 117/189 (61%), Gaps = 3/189 (1%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSER-GEQVTEKLASKYGRKNVL 236 M +K K +ITG ASG+GL S ELL+ GA + + ID+E G++ + L ++GR + Sbjct: 1 MQIKDKRVIITGVASGLGLTISRELLRNGASI-IAMIDAEESGKETVDILNKEFGRNRTI 59 Query: 237 FCRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRLWELEVDVNLNGVIRGTLLAY 416 F ++ + +F++ F V+ ++I++NNA N+ + +DVN+ VIR TLL Sbjct: 60 FYHCNIANNSEFDDTFKKAVKALGGLEILVNNADVTNETDFMKTIDVNVTSVIRATLLGI 119 Query: 417 RFMGKDRGGQGGVIVNTASTA--FARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTGVR 590 + M KD GG+GG IVN +S A +A PQ+ P+Y+AT +A+V +R++ YH TGV+ Sbjct: 120 QQMQKDLGGKGGAIVNISSLAGLYAAPQL--PVYSATKHAVVSFSRSFAQPYHYKRTGVK 177 Query: 591 CLVVCPGLT 617 LV+CP L+ Sbjct: 178 ILVMCPELS 186 >UniRef50_UPI0000D5767E Cluster: PREDICTED: similar to 15-hydroxyprostaglandin dehydrogenase; n=2; Tribolium castaneum|Rep: PREDICTED: similar to 15-hydroxyprostaglandin dehydrogenase - Tribolium castaneum Length = 255 Score = 138 bits (335), Expect = 1e-31 Identities = 84/189 (44%), Positives = 112/189 (59%), Gaps = 2/189 (1%) Frame = +3 Query: 63 DLKGKVALITGAASGIGLAYSEELLKQGAK-VSLCDIDSERGEQVTEKLASKYGRKNVLF 239 +LKGKVAL+TG ASGIGLA ELLK G K VS+ DI TE S+ V F Sbjct: 3 ELKGKVALVTGGASGIGLAMVRELLKNGIKAVSVVDISEN-----TELQDSR-----VTF 52 Query: 240 CRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRLWELEVDVNLNGVIRGTLLAYR 419 + DVT Q + AF TV +N++DIV+NNAG +++ W+ +D+NL VI GT LA R Sbjct: 53 IKTDVTCKKQLQAAFDKTVATYNQLDIVVNNAGVIDEIDWKRTIDINLVAVIEGTYLALR 112 Query: 420 -FMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTGVRCL 596 ++ K + GVIVNTAS P S PIY + + +VGL R+ G + + VR + Sbjct: 113 TYLPKYKSEAEGVIVNTASVLGLCPLQSAPIYCTSKHGVVGLGRSLGGPHIYDEYKVRIV 172 Query: 597 VVCPGLTDS 623 +CPGL D+ Sbjct: 173 TICPGLVDT 181 >UniRef50_Q9VV42 Cluster: CG4899-PA, isoform A; n=5; Sophophora|Rep: CG4899-PA, isoform A - Drosophila melanogaster (Fruit fly) Length = 278 Score = 136 bits (329), Expect = 5e-31 Identities = 71/204 (34%), Positives = 115/204 (56%), Gaps = 1/204 (0%) Frame = +3 Query: 48 SSINMDLKGKVALITGAASGIGLAYSEELLKQGA-KVSLCDIDSERGEQVTEKLASKYGR 224 S M +GK A++TG A GIGL S++LL GA KV++ D+ E V KL + + Sbjct: 14 SQTKMSFRGKNAVVTGGAGGIGLQVSKQLLAAGAAKVAIIDLQDNLEEFV--KLRAAHPT 71 Query: 225 KNVLFCRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRLWELEVDVNLNGVIRGT 404 ++V+ ++DV + E + + F IDIV+N AG ND+ + + VNL G+I T Sbjct: 72 QSVMIIKMDVANKKGVEATYEEIAKTFGNIDIVVNVAGIFNDKDVQRTLLVNLGGIINST 131 Query: 405 LLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTG 584 L A +MGKD GG+GG++VN +S P P+Y AT I+ TR ++ + +G Sbjct: 132 LSALPYMGKDNGGKGGIVVNMSSVVGLDPMFIIPVYGATKAGIINFTRCLANEKYYQRSG 191 Query: 585 VRCLVVCPGLTDSGLVXDLDKQLM 656 ++ + VCPG T + + + ++++ Sbjct: 192 IKFVTVCPGATMTDMFTNFTEKII 215 >UniRef50_UPI00015B5FC8 Cluster: PREDICTED: similar to putative alcohol dehydrogenase; n=2; Nasonia vitripennis|Rep: PREDICTED: similar to putative alcohol dehydrogenase - Nasonia vitripennis Length = 267 Score = 130 bits (315), Expect = 3e-29 Identities = 69/195 (35%), Positives = 111/195 (56%), Gaps = 4/195 (2%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAK-VSLCDI---DSERGEQVTEKLASKYGRK 227 M++K KVA++TG GIGL + L++ + V++ D+ DSE KL ++G+ Sbjct: 1 MEIKNKVAIVTGGIGGIGLVTVQHLIRSKIQFVAIIDLPKSDSEAAVANLSKLNKEFGKG 60 Query: 228 NVLFCRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRLWELEVDVNLNGVIRGTL 407 + + D+T+ +F + + +DI+IN AG +ND L ++VN V+ ++ Sbjct: 61 SYQYYSCDLTNIQEFRAIYEKVIALKKYVDILINAAGILNDNAMNLCINVNFTAVVNSSM 120 Query: 408 LAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTGV 587 +A M KD+GG+GGV+VN AS A PIY AT +A+V R+ + H + GV Sbjct: 121 IAIEHMRKDKGGKGGVVVNVASIAGIVDFPYNPIYNATKHAVVAFARSL--KPHNKIIGV 178 Query: 588 RCLVVCPGLTDSGLV 632 R + +CPG+TD+GLV Sbjct: 179 RVVCICPGVTDTGLV 193 >UniRef50_UPI00015B42E5 Cluster: PREDICTED: similar to putative alcohol dehydrogenase; n=3; Nasonia vitripennis|Rep: PREDICTED: similar to putative alcohol dehydrogenase - Nasonia vitripennis Length = 273 Score = 127 bits (306), Expect = 3e-28 Identities = 75/191 (39%), Positives = 107/191 (56%), Gaps = 1/191 (0%) Frame = +3 Query: 63 DLKGKVALITGAASGIGLAYSEELLKQGAK-VSLCDIDSERGEQVTEKLASKYGRKNVLF 239 ++K KV +ITG SGIGL+ ++ +LK GAK V+L ++D E V ++L +Y + F Sbjct: 19 EVKDKVVVITGGTSGIGLSIAKHMLKNGAKYVALFELDHENSRIVFDELHKQY-HDRIGF 77 Query: 240 CRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRLWELEVDVNLNGVIRGTLLAYR 419 DVT F +E IDI+INNAG +D EL VD+NL ++ + Sbjct: 78 YPCDVTKTDLIYNNFDKVMESHKTIDILINNAGIADDNKPELSVDINLKALVVASYKFIA 137 Query: 420 FMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTGVRCLV 599 +GK +GG+GGVIVN AS A P+Y AT + +VG TR Q +TGVR L Sbjct: 138 RIGKHKGGKGGVIVNIASIA-GIVSGFLPVYCATKHGVVGFTRTL--QMSYGLTGVRVLA 194 Query: 600 VCPGLTDSGLV 632 +CP T++ +V Sbjct: 195 ICPSFTNTPIV 205 >UniRef50_UPI00015B573D Cluster: PREDICTED: similar to putative alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to putative alcohol dehydrogenase - Nasonia vitripennis Length = 279 Score = 126 bits (303), Expect = 8e-28 Identities = 72/194 (37%), Positives = 111/194 (57%), Gaps = 1/194 (0%) Frame = +3 Query: 63 DLKGKVALITGAASGIGLAYSEELLKQGAK-VSLCDIDSERGEQVTEKLASKYGRKNVLF 239 D+K KV ++TG A+GIGL E L++GA+ V++ DI E +KL ++G V Sbjct: 9 DIKDKVIIVTGGANGIGLECVLEFLEKGARYVAILDITPENF--TADKLQEEFGTHRVDL 66 Query: 240 CRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRLWELEVDVNLNGVIRGTLLAYR 419 D+ + +F F +E+ N +DI+IN+AG N+ +DVN+ G I G L+A Sbjct: 67 YHCDIANEEEFRSNFKKVIEKHNYVDILINDAGVANENDTARLLDVNVKGTILGNLMAIE 126 Query: 420 FMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTGVRCLV 599 MGK +GG+GGV+VN AS P+Y+A+ +AIV TR+ + + + GV+ + Sbjct: 127 HMGKHKGGRGGVVVNVASVIGLLNCHVLPVYSASKHAIVSFTRSM--KSNCDRLGVKIIA 184 Query: 600 VCPGLTDSGLVXDL 641 VCPG T + L +L Sbjct: 185 VCPGHTRTKLNFEL 198 >UniRef50_UPI00015B4C63 Cluster: PREDICTED: similar to putative alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to putative alcohol dehydrogenase - Nasonia vitripennis Length = 271 Score = 124 bits (299), Expect = 2e-27 Identities = 71/207 (34%), Positives = 114/207 (55%), Gaps = 8/207 (3%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAK-VSLCDIDSERGEQVTEKLASKYGRKNVL 236 M++ KV +ITG G+G ++ LL GAK V+L D+ G+ EKL ++G+ Sbjct: 1 MEISNKVIIITGGVGGMGFETAKALLNHGAKFVALFDLTETDGQSAIEKLDKEFGKGRAG 60 Query: 237 FCRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRLWELEVDVNL-----NGVIRG 401 F D+ +FE+ F +++ ID++INNAG N++ E V+VN+ ++R Sbjct: 61 FYPGDIVIDSEFEDNFNRIIKDHGSIDVLINNAGIANEQNIERLVNVNVVSSIDKNILRA 120 Query: 402 T--LLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVN 575 + LLA MGK +GG+GG IVN + P Y+AT +AI+G TR + + Sbjct: 121 SQILLALNHMGKHKGGKGGAIVNVNAILGLIDCPILPFYSATKHAIIGFTRCMKENF--A 178 Query: 576 VTGVRCLVVCPGLTDSGLVXDLDKQLM 656 TGVR + VCPG+T + L+ ++ ++ Sbjct: 179 TTGVRVMSVCPGVTKTNLIKEIPNHIL 205 >UniRef50_UPI00015B42E2 Cluster: PREDICTED: similar to putative alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to putative alcohol dehydrogenase - Nasonia vitripennis Length = 266 Score = 122 bits (294), Expect = 9e-27 Identities = 69/194 (35%), Positives = 103/194 (53%), Gaps = 3/194 (1%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAK-VSLCDIDS--ERGEQVTEKLASKYGRKN 230 M++K KVA++TG GIG A + LL+ GAK V++ D+DS R K+ ++G+ Sbjct: 1 MNVKDKVAIVTGGTGGIGFATVQALLRHGAKYVAIFDLDSMHTRAASCIHKVEEEFGKDK 60 Query: 231 VLFCRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRLWELEVDVNLNGVIRGTLL 410 F DVT +F + V +DI++N A ++ +D+NL V+ TL+ Sbjct: 61 ADFYTCDVTIQSEFAARYDEIVGMQRTVDILVNYASIASEPRAHHMIDINLTAVVTCTLI 120 Query: 411 AYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTGVR 590 MG+ G+GG IVN S + PIYTAT Y + G T++ D H GVR Sbjct: 121 GIDRMGRHHNGRGGAIVNVCSVFGLTTSPAFPIYTATKYGVYGFTKSLKD--HYEHLGVR 178 Query: 591 CLVVCPGLTDSGLV 632 + VCPGLT++ L+ Sbjct: 179 VMAVCPGLTETSLL 192 >UniRef50_Q1HPX6 Cluster: Alcohol dehydrogenase; n=1; Bombyx mori|Rep: Alcohol dehydrogenase - Bombyx mori (Silk moth) Length = 289 Score = 120 bits (290), Expect = 3e-26 Identities = 74/230 (32%), Positives = 120/230 (52%), Gaps = 2/230 (0%) Frame = +3 Query: 63 DLKGKVALITGAASGIGLAYSEELLKQGAKVSLC-DIDSERGEQVTEKLASKYGRKNVLF 239 +++GKV +ITGAA GIG A ++ LK GAKV + DI+ +G Q ++L KYG+ F Sbjct: 30 EIEGKVVVITGAAQGIGYAIADNFLKNGAKVIIILDINVPKGIQAAKELNCKYGKNKAEF 89 Query: 240 CRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRLWELEVDVNLNGVIRGTLLAYR 419 D+T E + +++ +D+++NNAG + + N I +L Sbjct: 90 IECDITK--DLERISKIIYKKYKYVDVLVNNAGIFKEIKPRKLLLTNAVATIEFSLKFME 147 Query: 420 FMGKDR-GGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTGVRCL 596 M KD+ G+GG I+N AST P Y T +AI+G +R+ G +Y+ GVR L Sbjct: 148 NMRKDKLSGKGGTIINIASTVVHYIDPFFPTYRGTKFAIMGFSRSLGHEYNYKKNGVRVL 207 Query: 597 VVCPGLTDSGLVXDLDKQLMSSKYETAWLEDITDSKCRALITLGKPLVDV 746 +CPG T++ L LD ++S+ A ++ ++ +GK V++ Sbjct: 208 TICPGETNTTL--GLDNTKVNSEDAPALAKEYQYPTIQSPDNVGKGAVEI 255 >UniRef50_UPI00015B5A58 Cluster: PREDICTED: similar to putative alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to putative alcohol dehydrogenase - Nasonia vitripennis Length = 263 Score = 120 bits (288), Expect = 5e-26 Identities = 71/202 (35%), Positives = 108/202 (53%), Gaps = 4/202 (1%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAK-VSLCDIDSERG--EQVTEKLASKYGRKN 230 M +K KV +ITG G+ A ++ LLK + ++L D + + E +K ++G Sbjct: 1 MYIKNKVIIITGGLGGLATATTQVLLKHEPRYIALFDTEEKNSYAELQLKKFEQEFGEGR 60 Query: 231 VLFCRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRLWELEVDVNLNGVIRGTLL 410 V F DV + QFEE + ++ +DI+IN AG + D EL +DVN G++ TL Sbjct: 61 VGFYASDVRNQHQFEEKYDQVLKSHKSVDILINLAGILCDADTELTIDVNFKGLVFCTLT 120 Query: 411 AYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTGVR 590 A MG RGG+GG I+N +S P+Y AT +A+V T + + H TGVR Sbjct: 121 AIDKMGIHRGGRGGTIINVSSIVGLMFHEDFPVYVATKHAVVAFTNSL--KSHYAKTGVR 178 Query: 591 CLVVCPGLTDSGLV-XDLDKQL 653 + +CPGLT + ++ D+ K L Sbjct: 179 AMTMCPGLTSTSMIRTDIAKPL 200 >UniRef50_Q1G151 Cluster: Putative alcohol dehydrogenase; n=1; Bombyx mori|Rep: Putative alcohol dehydrogenase - Bombyx mori (Silk moth) Length = 274 Score = 118 bits (285), Expect = 1e-25 Identities = 66/194 (34%), Positives = 102/194 (52%), Gaps = 3/194 (1%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAK-VSLCDIDSERGEQVTEKLASKYGRKNVL 236 +D+ KV L+TG A+G+G + LL + A+ V+ D+ G + +L K+G V Sbjct: 10 VDVDDKVFLVTGGAAGVGAGLVKALLFENARHVAFLDVADREGAALEAQLIIKFGALRVK 69 Query: 237 FCRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMN--DRLWELEVDVNLNGVIRGTLL 410 F + DV D Q A+ ++++ R+D VIN+A ++ D + +D+N G + TL Sbjct: 70 FIKCDVGDERQLASAYKQVLDKYKRLDGVINSAAVLSVDDNSFNRMIDINFTGTVNSTLK 129 Query: 411 AYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTGVR 590 A MG D+GG GGVIVN +S P+Y AT A++ + G Q T VR Sbjct: 130 ALDIMGADKGGSGGVIVNISSLLALNLTSHLPVYAATKAAVLQFSIRMGTQEQFTRTKVR 189 Query: 591 CLVVCPGLTDSGLV 632 L VC G TD+ ++ Sbjct: 190 VLSVCLGPTDTAIL 203 >UniRef50_Q9I7R3 Cluster: CG18814-PA; n=3; Sophophora|Rep: CG18814-PA - Drosophila melanogaster (Fruit fly) Length = 285 Score = 115 bits (277), Expect = 1e-24 Identities = 68/223 (30%), Positives = 110/223 (49%), Gaps = 18/223 (8%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLF 239 MDL+GK + G GIG +ELLK+ K L D + + + ++ + + Sbjct: 1 MDLEGKNVVYLGGFGGIGKKCVQELLKKQIK-GLAIFDLIVDDDLLAEWKKQHPDTEIFY 59 Query: 240 CRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRLWELEVDVNLN----------- 386 ++D+T + A+ T E+ D+V+N +G ++DR EL + +NL Sbjct: 60 QKMDITQKSDIDAAYKATAEKLGHFDVVVNGSGLLDDRRIELTIQINLVILEIVLSKGFI 119 Query: 387 -------GVIRGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLT 545 GVI TL A +M K +GG+GG+IVN +S A +P IY+ + + T Sbjct: 120 YQYFLKVGVINSTLTALEYMDKSKGGRGGLIVNISSVAGLQPTPLMAIYSTSKTGVTTFT 179 Query: 546 RAYGDQYHVNVTGVRCLVVCPGLTDSGLVXDLDKQLMSSKYET 674 RA H +GV + +CPG T++G++ D+DK+ YET Sbjct: 180 RAMASPIHYAHSGVGFITICPGYTNTGILKDIDKKTTFPFYET 222 >UniRef50_A3I573 Cluster: Short chain dehydrogenase; n=2; Bacillus sp. B14905|Rep: Short chain dehydrogenase - Bacillus sp. B14905 Length = 252 Score = 110 bits (265), Expect = 3e-23 Identities = 70/209 (33%), Positives = 112/209 (53%), Gaps = 6/209 (2%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLF 239 M+ K+A++TGA SGIG A S +L GAKV + D + E GE+ T KL + G + + F Sbjct: 1 MEHLNKIAVVTGAGSGIGRASSLKLASNGAKVVIVDFNKETGEE-TLKLVKEQGGEGI-F 58 Query: 240 CRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMN-----DRLWELEVDVNLNGVIRGT 404 + DV+ E+ VE + RID+ NNAG + + + E D ++ ++G Sbjct: 59 VQADVSKSEDVEKYVNAAVETYGRIDVFFNNAGVIQKISPLTEIADSEYDRIMSINVKGV 118 Query: 405 LLAYRFMGKDRGGQG-GVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVT 581 L + + K GQG G I+NTASTA R + S +Y+A+ +A++GLT++ +Y Sbjct: 119 FLGLKHVIKVMEGQGSGSIINTASTAGVRSEHSMAVYSASKHAVIGLTKSASLEYVKK-- 176 Query: 582 GVRCLVVCPGLTDSGLVXDLDKQLMSSKY 668 G+R +CPG ++ L + + Y Sbjct: 177 GIRINAICPGGVETALTNSVTAMFETGGY 205 >UniRef50_Q9NAR7 Cluster: Alcohol dehydrogenase; n=23; Schizophora|Rep: Alcohol dehydrogenase - Bactrocera oleae (Olive fruit fly) Length = 258 Score = 110 bits (264), Expect = 4e-23 Identities = 66/231 (28%), Positives = 117/231 (50%), Gaps = 1/231 (0%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELL-KQGAKVSLCDIDSERGEQVTEKLASKYGRKNVL 236 M L GK + G IG ++++ K A + D+ E E + + L + + V Sbjct: 1 MGLSGKNVVFVGGLGFIGYEACKQIMTKNVASFFVFDV-LENAENI-KALQAINPKTKVY 58 Query: 237 FCRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRLWELEVDVNLNGVIRGTLLAY 416 + + D+T+ + AF + + ID+++N AG + D EL +++NL G+I TL A Sbjct: 59 YTKFDITNKASIKSAFADVIAKVQYIDVLVNGAGILTDPNVELTMNINLIGLINTTLEAI 118 Query: 417 RFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTGVRCL 596 M K++ G+GG+IVN AS P IY A+ + ++G +R+ D Y+ N+TG+ Sbjct: 119 PLMDKNKKGRGGLIVNIASVLGLEPAPPAAIYCASKFGVMGFSRSISDPYYYNLTGIAVA 178 Query: 597 VVCPGLTDSGLVXDLDKQLMSSKYETAWLEDITDSKCRALITLGKPLVDVL 749 CPGLT++ L ++ + + +Y + + ++K + G L VL Sbjct: 179 TFCPGLTETPLKNNIATK-YTFEYSKVIGDKLNNTKTQKPEACGAHLAQVL 228 >UniRef50_A4AQP7 Cluster: 3-ketoacyl-(Acyl-carrier-protein) reductase; n=3; Bacteroidetes|Rep: 3-ketoacyl-(Acyl-carrier-protein) reductase - Flavobacteriales bacterium HTCC2170 Length = 252 Score = 109 bits (261), Expect = 9e-23 Identities = 75/212 (35%), Positives = 115/212 (54%), Gaps = 10/212 (4%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLF 239 M+L+ KV +ITGA SGIG A + QGAKV + D++ ER + V ++ K G ++ F Sbjct: 1 MELENKVVVITGAGSGIGAATASLFAAQGAKVIVADLNMERAQDVVGRI-KKAGGTSLAF 59 Query: 240 CRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRL----------WELEVDVNLNG 389 + +VT + + E T++E++R+D+++NNAG + W + VN G Sbjct: 60 -KTNVTKFDEIEVLISKTIKEYSRLDVMVNNAGIGGENQKKTADHTHEDWHNVIAVNQTG 118 Query: 390 VIRGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYH 569 V +A R M K G G IVN AS A +P Y+A+ YA+VG+T++ +Y Sbjct: 119 VFYCMQVALRQMMKQ--GYGN-IVNVASLAGLKPSGYNLSYSASKYAVVGMTKSAALEY- 174 Query: 570 VNVTGVRCLVVCPGLTDSGLVXDLDKQLMSSK 665 +R VCPG T+S L+ K+L+SSK Sbjct: 175 -GRKNIRINAVCPGYTNSALL----KKLLSSK 201 >UniRef50_Q5TWK5 Cluster: ENSANGP00000025423; n=1; Anopheles gambiae str. PEST|Rep: ENSANGP00000025423 - Anopheles gambiae str. PEST Length = 191 Score = 108 bits (260), Expect = 1e-22 Identities = 60/188 (31%), Positives = 101/188 (53%), Gaps = 2/188 (1%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLF 239 M L G+ A++ G G+G+A + LL+QG K LC +D + GR ++ Sbjct: 1 MSLAGQSAVVFGGCGGMGMAIGQHLLRQGVK-KLCIVDVVELTDSNLSCLKESGRDALIL 59 Query: 240 CRL-DVTDYPQFEEAFVMTVEE-FNRIDIVINNAGFMNDRLWELEVDVNLNGVIRGTLLA 413 C++ D+++ ++ + E IDI++N+AG + + + + GVI L+A Sbjct: 60 CKICDISNRAALKQLLERDISEALGSIDILVNSAGIVESEVPDKLIGT---GVINSCLIA 116 Query: 414 YRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTGVRC 593 M + +GG+GGVIVN ASTA P P Y A+ + ++G TR+ G + + TGV+ Sbjct: 117 LNLMSRAKGGKGGVIVNVASTAGLEPIPFLPTYCASKHGLIGFTRSLGVEPVYSETGVKF 176 Query: 594 LVVCPGLT 617 +++CPG T Sbjct: 177 IIICPGGT 184 >UniRef50_A0G4K1 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Burkholderia phymatum STM815|Rep: Short-chain dehydrogenase/reductase SDR - Burkholderia phymatum STM815 Length = 263 Score = 106 bits (255), Expect = 5e-22 Identities = 66/199 (33%), Positives = 104/199 (52%), Gaps = 9/199 (4%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLF 239 +DL G+VA++TG +GIGLA S L GAK + I ++G+ E++ G +V+F Sbjct: 2 IDLNGRVAVVTGGETGIGLAISRTLALAGAKTVIGGILDDKGQAAAEQIKKDGG--DVVF 59 Query: 240 CRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFM---------NDRLWELEVDVNLNGV 392 + DV+ Q E V+ F ++DI++NNAG + LW+ +D+NL GV Sbjct: 60 IKTDVSAEEQVEALVQSAVDRFGKLDIMVNNAGVFDGFADCVETSPALWDRVIDINLRGV 119 Query: 393 IRGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHV 572 GT A + M R G+ I+NT+S R YTA+ +AI+GLT+ + Sbjct: 120 FLGTRAALKRMTPQRYGR---IINTSSVGGMRGSADGCSYTASKFAIIGLTKQVACTH-- 174 Query: 573 NVTGVRCLVVCPGLTDSGL 629 + G+ +CPG+ + L Sbjct: 175 SQYGITVNAICPGVIQTDL 193 >UniRef50_UPI00015B572C Cluster: PREDICTED: similar to putative alcohol dehydrogenase; n=2; Nasonia vitripennis|Rep: PREDICTED: similar to putative alcohol dehydrogenase - Nasonia vitripennis Length = 268 Score = 106 bits (254), Expect = 7e-22 Identities = 63/190 (33%), Positives = 101/190 (53%), Gaps = 4/190 (2%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAK-VSLCDIDSERGEQVT---EKLASKYGRK 227 MD+ KV ++TG GIG + L++GAK V++ D+D E E+V ++L ++ + Sbjct: 1 MDINNKVGVVTGGLRGIGYVIVQHFLRRGAKFVAIFDLDVEEHEEVVNALKQLEQEFAAQ 60 Query: 228 NVLFCRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRLWELEVDVNLNGVIRGTL 407 + DVT++ +F + +DI++NNAG + +L V VN VI T+ Sbjct: 61 RFSYYCCDVTNFKKFIACYDEVYTTNGAVDILVNNAGVFAEHDQDLTVAVNFTSVIHCTM 120 Query: 408 LAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTGV 587 A MG ++GG+GGVIV S + P+Y+AT A+ R+ D Y+ GV Sbjct: 121 HAIERMGTNKGGKGGVIVTIGSICALISLSTIPVYSATKGALACFVRSTKD-YNAKY-GV 178 Query: 588 RCLVVCPGLT 617 R + +CPG+T Sbjct: 179 RIVCLCPGMT 188 >UniRef50_Q67M07 Cluster: Short-chain dehydrogenase; n=2; Bacteria|Rep: Short-chain dehydrogenase - Symbiobacterium thermophilum Length = 254 Score = 106 bits (254), Expect = 7e-22 Identities = 64/198 (32%), Positives = 99/198 (50%), Gaps = 9/198 (4%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 L GKVA+ITGAA G+G A +E ++GA+V + D++ E G K+ G F R Sbjct: 4 LDGKVAIITGAAMGMGAATAELFAREGARVVIADLNEELGRAQARKIQDAGGA--AAFVR 61 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF---------MNDRLWELEVDVNLNGVIR 398 DV+ E V+ F R+D+ +NNA +++ +W+ + V+L GV Sbjct: 62 ADVSRAGDVEAMVQFAVDTFGRLDVAVNNAAHSPDTRPLADLDEAVWDAVIGVDLKGV-- 119 Query: 399 GTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNV 578 L Y + G GG I+N +S + RPQ TP Y A + ++GLT+ Y + Sbjct: 120 ALCLKYELRQMLKQGGGGSIINISSVSGIRPQPGTPAYVAAKHGVIGLTKQAAMDYSPH- 178 Query: 579 TGVRCLVVCPGLTDSGLV 632 G+R V PG D+ ++ Sbjct: 179 -GIRVNAVAPGAVDTPML 195 >UniRef50_Q026V2 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Solibacter usitatus Ellin6076|Rep: Short-chain dehydrogenase/reductase SDR - Solibacter usitatus (strain Ellin6076) Length = 275 Score = 105 bits (253), Expect = 9e-22 Identities = 71/196 (36%), Positives = 102/196 (52%), Gaps = 9/196 (4%) Frame = +3 Query: 69 KGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCRL 248 +GKVA +TG SG+G A SEEL ++GA +++ DI++E E V + G+ + +L Sbjct: 5 QGKVAFVTGGGSGLGRALSEELARRGAVIAVTDINAEAAEHVAAAITESGGKSCSM--KL 62 Query: 249 DVTDYPQFEEAFVMTVEEFNRIDIVINNAGF--------MNDRLWELEVDVNLNGVIRGT 404 DV+ + V + R+D + NNAG M W +DVNL GV+ GT Sbjct: 63 DVSQPEDVAASIDSVVGRYGRLDYMFNNAGIIILGEVRDMGLEHWHRLIDVNLLGVLYGT 122 Query: 405 LLAYRFMGKDRGGQG-GVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVT 581 AY M + QG G IVN AS P + Y AT +A+VGL+ + + + Sbjct: 123 TAAYSHMVR----QGYGHIVNIASVGGLVPLPTYAAYAATKHAVVGLSTSMRPE--ASKL 176 Query: 582 GVRCLVVCPGLTDSGL 629 GVR VVCPG ++GL Sbjct: 177 GVRITVVCPGTMNTGL 192 >UniRef50_Q737G7 Cluster: Short chain dehydrogenase family protein; n=3; Bacillus cereus group|Rep: Short chain dehydrogenase family protein - Bacillus cereus (strain ATCC 10987) Length = 273 Score = 105 bits (251), Expect = 2e-21 Identities = 72/192 (37%), Positives = 99/192 (51%), Gaps = 9/192 (4%) Frame = +3 Query: 75 KVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCRLDV 254 +VA++TG ASGIG A + +L + V + DI+ G+++ + K + F LDV Sbjct: 5 RVAIVTGGASGIGKALAIQLANKDIFVIIADINETSGQELVNNI--KNNNQLARFEYLDV 62 Query: 255 TDYPQFEEAFVMTVEEFNRIDIVINNAGF--------MNDRLWELEVDVNLNGVIRGTLL 410 T+ EE + V EF RID + NNAG M+ W+ +++NL GVI GT L Sbjct: 63 TNAGSVEELIIKIVNEFGRIDYMFNNAGIAMYGEVFDMSLDNWKHIIEINLLGVIYGTQL 122 Query: 411 AYRFMGKDRGGQG-GVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTGV 587 AY+FM K QG G I+NTAS P Y T +AIVGLT + Y GV Sbjct: 123 AYQFMKK----QGFGHIINTASATGLGPAPLCTAYATTKHAIVGLTTSL--HYEAEEYGV 176 Query: 588 RCLVVCPGLTDS 623 V+CP D+ Sbjct: 177 NVSVLCPTFVDT 188 >UniRef50_A6CNE9 Cluster: Cyclohexanol dehydrogenase; n=3; Bacillus|Rep: Cyclohexanol dehydrogenase - Bacillus sp. SG-1 Length = 279 Score = 105 bits (251), Expect = 2e-21 Identities = 68/197 (34%), Positives = 105/197 (53%), Gaps = 9/197 (4%) Frame = +3 Query: 69 KGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCRL 248 + K A+ITGA SG+G + + L K+G +++ DI+ E G + E + K N +F + Sbjct: 31 ENKAAIITGAGSGLGQSAAVRLAKEGIDIAVVDINEEGGNETVEMVKQK--GVNAIFIKA 88 Query: 249 DVTDYPQFEEAFVMTVEEFNRIDIVINNAG-------FMNDRLWELE--VDVNLNGVIRG 401 DV+ + + TVEEF ++D NNAG F+N + E+E V +NL G + G Sbjct: 89 DVSKAEEVKNYVDKTVEEFGKVDYFFNNAGISGSGQYFLNTEIEEIEQVVSINLMGALYG 148 Query: 402 TLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVT 581 M K+ GG IVNTAS+A Q S Y+AT + I+GLT++ +Y Sbjct: 149 VRYVAEVMMKNGGGS---IVNTASSAGVIGQDSVVTYSATKHGIIGLTKSMVAEYAKE-- 203 Query: 582 GVRCLVVCPGLTDSGLV 632 G+R + PG T++ +V Sbjct: 204 GLRVNAIAPGPTETPMV 220 >UniRef50_A1BFL6 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=2; Chlorobium/Pelodictyon group|Rep: Short-chain dehydrogenase/reductase SDR precursor - Chlorobium phaeobacteroides (strain DSM 266) Length = 280 Score = 104 bits (250), Expect = 2e-21 Identities = 74/215 (34%), Positives = 107/215 (49%), Gaps = 8/215 (3%) Frame = +3 Query: 72 GKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCRLD 251 GK A++TGAASGIG A + L+++GA+V + DIDS E+ L + G V LD Sbjct: 7 GKNAIVTGAASGIGFALAVGLIERGARVWVADIDSAGVERAAASLGA--GAHPV---TLD 61 Query: 252 VTDYPQFEEAFVMTVEEFNRIDIVINNAGFMND-RLWELE-------VDVNLNGVIRGTL 407 V D F + + ID + NNAG ++ + E + +DVN+ GV+ GTL Sbjct: 62 VRDAVAFRDLVAGVARDAGGIDFLFNNAGILHSGEVCEFDEEQCNRIIDVNIRGVVNGTL 121 Query: 408 LAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTGV 587 AY M + R G IVNTAS A P Y T +A+VG + + ++ GV Sbjct: 122 AAYPLMVRQRSGH---IVNTASLAGLAPAPLLSTYAMTKHAVVGFSSSL--RFEAERYGV 176 Query: 588 RCLVVCPGLTDSGLVXDLDKQLMSSKYETAWLEDI 692 R +CP D+ L LD++ +S W D+ Sbjct: 177 RVSAICPAGVDTPL---LDEEAISGAGRAGWRPDV 208 >UniRef50_Q8CUW5 Cluster: 3-oxoacyl-(Acyl carrier protein) reductase; n=9; Firmicutes|Rep: 3-oxoacyl-(Acyl carrier protein) reductase - Oceanobacillus iheyensis Length = 253 Score = 103 bits (248), Expect = 4e-21 Identities = 66/194 (34%), Positives = 104/194 (53%), Gaps = 10/194 (5%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLF 239 M LK KVA++TGAASG+G A + +GAKV + D++ E + V E++ S G + Sbjct: 1 MKLKDKVAIVTGAASGMGKAIATLYASEGAKVIVADLNEEGAQSVVEEITSNNGVATAI- 59 Query: 240 CRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMN---------DRLWELEVDVNLNGV 392 ++++ ++ V+ + +DI++NNAG M+ D W+L D+N GV Sbjct: 60 -KVNIAQKEDIDKMIDTAVDTYGTLDILVNNAGIMDGFEAVGDVEDDRWDLIFDINTKGV 118 Query: 393 IRGTLLAYR-FMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYH 569 +R A F+ K + GVIVNTAST + Y A+ +A++GLT+ G Y Sbjct: 119 MRAMRKAIPIFLEK----ESGVIVNTASTGGLNGAHAGAAYGASKHAVIGLTKNTGYMY- 173 Query: 570 VNVTGVRCLVVCPG 611 N +G+RC + PG Sbjct: 174 AN-SGIRCNAIAPG 186 >UniRef50_A1IFS9 Cluster: Short chain dehydrogenase family protein; n=1; Candidatus Desulfococcus oleovorans Hxd3|Rep: Short chain dehydrogenase family protein - Candidatus Desulfococcus oleovorans Hxd3 Length = 273 Score = 103 bits (247), Expect = 5e-21 Identities = 80/229 (34%), Positives = 110/229 (48%), Gaps = 11/229 (4%) Frame = +3 Query: 75 KVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCRLDV 254 KV ++TG ASG+G A E L +GA + + DID E E+V + + GR +F LD Sbjct: 7 KVFIVTGGASGMGRAVCELLGTRGAILIIADIDGESAEKVAAGITAAGGRATGVF--LDT 64 Query: 255 TDYPQFEEAFVMTVEEFNRIDIVINNAGF--------MNDRLWELEVDVNLNGVIRGTLL 410 T T E+ R+D + NNAG M+D W +DVN GV+ GTL Sbjct: 65 TADETVRRLVDETAAEYGRLDYMFNNAGILIAGEVRDMSDDHWARILDVNFRGVLTGTLA 124 Query: 411 AYRFMGKDRGGQG-GVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTGV 587 AYR M + QG G I+NTASTA P Y T +A+VGL+ + + GV Sbjct: 125 AYRIMVE----QGFGHIINTASTAGLVPIPVITAYATTKHAVVGLSISLRPE--AAKAGV 178 Query: 588 RCLVVCPGLTDSGLV--XDLDKQLMSSKYETAWLEDITDSKCRALITLG 728 R VVCPG + + + K M+ T ++ I+ K I G Sbjct: 179 RVSVVCPGYVSTSIFDKGTVVKGDMAGLLSTMPIKPISPEKAAGYIVRG 227 >UniRef50_Q4WXH0 Cluster: 15-hydroxyprostaglandin dehydrogenase (NAD(+)); n=2; Pezizomycotina|Rep: 15-hydroxyprostaglandin dehydrogenase (NAD(+)) - Aspergillus fumigatus (Sartorya fumigata) Length = 227 Score = 103 bits (247), Expect = 5e-21 Identities = 73/205 (35%), Positives = 112/205 (54%), Gaps = 21/205 (10%) Frame = +3 Query: 78 VALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCRLDVT 257 VA++TGA+SG+GLA ++ L+ +G +V++ DID++ G +V ++ + VLFCR DVT Sbjct: 5 VAVVTGASSGMGLAVTKHLVAKGWRVAMADIDADSGRKVAAEIGDQ-----VLFCRTDVT 59 Query: 258 DYPQ----FEEAFVMTVEEFNRIDIVINNAGFM-------NDRLWE----------LEVD 374 YPQ FE AF + R+D+ NAG ND ++ +D Sbjct: 60 SYPQQASLFETAFAWGGD---RLDLYAANAGIADTQFLCNNDYRYDENGLRLPVSLQTLD 116 Query: 375 VNLNGVIRGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAY 554 VNL VI+G L + +++ GG +V T+S+A P S PIYTA+ +A+VGLTRA Sbjct: 117 VNLTAVIQGVWLFKHYARRNKVA-GGKVVITSSSAGLYPMESDPIYTASKHALVGLTRAL 175 Query: 555 GDQYHVNVTGVRCLVVCPGLTDSGL 629 G + ++ +CP +GL Sbjct: 176 GPV--LQRQNIQVNAICPAFVPTGL 198 >UniRef50_Q8ELC2 Cluster: Oxidoreductase; n=2; Bacillaceae|Rep: Oxidoreductase - Oceanobacillus iheyensis Length = 244 Score = 103 bits (246), Expect = 6e-21 Identities = 65/207 (31%), Positives = 106/207 (51%), Gaps = 8/207 (3%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLF 239 M L+ KVA+ITG SGIG A ++ +GAK+ L D++ E+G + +L S+ +F Sbjct: 1 MKLQDKVAVITGGVSGIGAATAKLFASEGAKLILVDMNEEKGASIEAELKSQ--GSEAIF 58 Query: 240 CRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF--------MNDRLWELEVDVNLNGVI 395 + DVT+ Q + + ++ F ++DI+ NNAG + W V+V+L+GV Sbjct: 59 IKADVTNEEQVKNIYTTAIDTFGKVDILFNNAGIGAVKPTEELTYAEWRKTVEVDLDGVF 118 Query: 396 RGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVN 575 L+A + + GVIVNTAS + Y A +V LTR+ G +Y Sbjct: 119 ---LVAQAAIKEFLKAGSGVIVNTASMYGWVGSPGSAAYNAAKAGVVNLTRSLGLEYAAR 175 Query: 576 VTGVRCLVVCPGLTDSGLVXDLDKQLM 656 +R +CPG D+ ++ D D++ + Sbjct: 176 --NIRVNALCPGFIDTAILGDSDREAL 200 >UniRef50_P54398 Cluster: Fat body protein 2; n=6; Schizophora|Rep: Fat body protein 2 - Drosophila melanogaster (Fruit fly) Length = 256 Score = 102 bits (245), Expect = 8e-21 Identities = 58/193 (30%), Positives = 103/193 (53%) Frame = +3 Query: 63 DLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFC 242 D GK + G+ SGIG +L+++ K+ E E + +KL + V+F Sbjct: 3 DWTGKNVVYVGSFSGIGWQMMMQLMQKDIKMMGIMHRMENVEMM-KKLQAINPSVKVVFM 61 Query: 243 RLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRLWELEVDVNLNGVIRGTLLAYRF 422 ++++ + E+A + ID++IN G + D+ E + +NL G+I+ T++A + Sbjct: 62 QMNLMEKMSIEQAMKKMGQMMGHIDVMINGEGVLLDKDVETTMGMNLTGMIQSTMMAMPY 121 Query: 423 MGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTGVRCLVV 602 M K + G GG++VN +S P + +Y A + I+G TR+ GD+ TGV + + Sbjct: 122 MDKTQMGMGGMVVNMSSVYGLEPAPAFAVYAAAMHGILGFTRSMGDKMIYQKTGVMFMAM 181 Query: 603 CPGLTDSGLVXDL 641 CPGLT+S ++ +L Sbjct: 182 CPGLTNSEMIMNL 194 >UniRef50_Q5P8S6 Cluster: Putative dehydrogenase; n=4; Proteobacteria|Rep: Putative dehydrogenase - Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum (strain EbN1)) Length = 267 Score = 101 bits (241), Expect = 3e-20 Identities = 72/201 (35%), Positives = 105/201 (52%), Gaps = 9/201 (4%) Frame = +3 Query: 54 INMDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNV 233 + +L GKVA ++GAASGIG A + +GA V L D+ ERGE V + + GR Sbjct: 1 MKQNLSGKVAYVSGAASGIGAAIARVFAAEGASVLLGDVQVERGETVAAHIREQGGR--A 58 Query: 234 LFCRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF-MNDRLWELE-------VDVNLNG 389 LF DV+D Q+E A VEEF +D+++NNAG L ++E + VN+ G Sbjct: 59 LFIHHDVSDERQWESALACAVEEFGGMDLLVNNAGIEQTGLLADVELADINKLLAVNVAG 118 Query: 390 VIRGTLLAYRFMGK-DRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQY 566 VI G A R M G+GG I+N +S A + +Y+AT A+ L++A + Sbjct: 119 VILGHKHAIRTMRPGGSAGKGGSIINLSSVAGLIGTPALGVYSATKGAVRLLSKAAAVEC 178 Query: 567 HVNVTGVRCLVVCPGLTDSGL 629 G+R + PGL D+ + Sbjct: 179 GRLGYGIRVNSIHPGLVDTDM 199 >UniRef50_Q99714 Cluster: 3-hydroxyacyl-CoA dehydrogenase type-2; n=109; cellular organisms|Rep: 3-hydroxyacyl-CoA dehydrogenase type-2 - Homo sapiens (Human) Length = 261 Score = 101 bits (241), Expect = 3e-20 Identities = 72/213 (33%), Positives = 108/213 (50%), Gaps = 17/213 (7%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 +KG VA+ITG ASG+GLA +E L+ QGA L D+ + GE +KL + N +F Sbjct: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGN-----NCVFAP 62 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF-MNDRLWELE-------------VDVNL 383 DVT + A + +F R+D+ +N AG + + + L+ +DVNL Sbjct: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122 Query: 384 NGVIRGTLLAYRFMGK---DRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAY 554 G L MG+ D+GGQ GVI+NTAS A QV Y+A+ IVG+T Sbjct: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182 Query: 555 GDQYHVNVTGVRCLVVCPGLTDSGLVXDLDKQL 653 + G+R + + PGL + L+ L +++ Sbjct: 183 ARD--LAPIGIRVMTIAPGLFGTPLLTSLPEKV 213 >UniRef50_Q1IU03 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Acidobacteria bacterium Ellin345|Rep: Short-chain dehydrogenase/reductase SDR precursor - Acidobacteria bacterium (strain Ellin345) Length = 252 Score = 99 bits (238), Expect = 6e-20 Identities = 66/196 (33%), Positives = 97/196 (49%), Gaps = 8/196 (4%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLF 239 M LKGK A++TGAA+GIG A +E +GA + D+D + E + K+ S G L Sbjct: 1 MKLKGKTAIVTGAAAGIGKASTELFASEGAHILAIDLDGGKLEHLASKITSSGG--ICLA 58 Query: 240 CRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFM--------NDRLWELEVDVNLNGVI 395 R DV+ + A + F +IDI+ NNAG + + W+ + +N+ + Sbjct: 59 LRGDVSQSADVQNALNTAIGRFGKIDILFNNAGIVPAGKIDVTTEEQWDRAMAINVKSMY 118 Query: 396 RGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVN 575 L + + + GGVI+NTAS R V YTAT A+VGLT++ Y + Sbjct: 119 ---LFCHAIVPHFKEHGGGVILNTASATALRAVVDRACYTATKAAVVGLTKSMALDYVRD 175 Query: 576 VTGVRCLVVCPGLTDS 623 V CL CPG D+ Sbjct: 176 NIRVNCL--CPGTVDT 189 >UniRef50_Q8EXX5 Cluster: 3-ketoacyl-acyl carrier protein reductase; n=7; Bacteria|Rep: 3-ketoacyl-acyl carrier protein reductase - Leptospira interrogans Length = 254 Score = 99.1 bits (236), Expect = 1e-19 Identities = 61/209 (29%), Positives = 106/209 (50%), Gaps = 8/209 (3%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLF 239 +DLKGK A++TGAA GIG + + L K GA + + D++ E + ++++ + G K + Sbjct: 2 IDLKGKNAVVTGAARGIGKSTALTLAKAGANLVIADLNEESSKATADEISKQTGVK-AIG 60 Query: 240 CRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRL--------WELEVDVNLNGVI 395 +V+D +A V+EF +DI++NNAG D L W+ + VNL G Sbjct: 61 IGTNVSDVDSAAKAIQACVDEFGSVDILVNNAGITKDTLLMRMKKEQWDAVIAVNLTGTF 120 Query: 396 RGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVN 575 T A +FM K+ GG I+N +S A + Y+A+ ++G T+A + Sbjct: 121 NCTQAAIKFMMKN--PNGGSIINLSSIAGVNGNIGQTNYSASKAGVIGFTKAVA--LEMA 176 Query: 576 VTGVRCLVVCPGLTDSGLVXDLDKQLMSS 662 VRC + PG + + + +++ ++ Sbjct: 177 SRKVRCNAIAPGFIATEMTDAIPEKIRTA 205 >UniRef50_Q9PCQ2 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase; n=11; Bacteria|Rep: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase - Xylella fastidiosa Length = 255 Score = 98.3 bits (234), Expect = 2e-19 Identities = 70/202 (34%), Positives = 96/202 (47%), Gaps = 9/202 (4%) Frame = +3 Query: 63 DLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFC 242 D KG+VAL+TGAA+G+GLA + + GA V L D D ER Q + ++ G L C Sbjct: 6 DFKGQVALVTGAAAGMGLATARGFAQGGASVVLADRDGERAAQEAAAIVAEGGTAIGLAC 65 Query: 243 RLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFM---------NDRLWELEVDVNLNGVI 395 DV+D Q TV E+ R+D NNAG M ++ + +NL GV Sbjct: 66 --DVSDEAQVAALVEKTVAEYGRLDFAFNNAGVMAKIAPFAEATSEEFDRVIGINLRGV- 122 Query: 396 RGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVN 575 + Y R G GVIVN AS V Y A+ + ++GLTRA +Y Sbjct: 123 -WLCMKYELQQMQRQG-SGVIVNNASVGALTGNVGIGAYIASKHGVLGLTRAAALEYCKK 180 Query: 576 VTGVRCLVVCPGLTDSGLVXDL 641 G+R V PG D+ + D+ Sbjct: 181 --GIRVNAVNPGTIDTQIARDV 200 >UniRef50_Q1YQZ7 Cluster: Short chain dehydrogenase family protein; n=1; gamma proteobacterium HTCC2207|Rep: Short chain dehydrogenase family protein - gamma proteobacterium HTCC2207 Length = 282 Score = 97.9 bits (233), Expect = 2e-19 Identities = 67/190 (35%), Positives = 95/190 (50%), Gaps = 9/190 (4%) Frame = +3 Query: 69 KGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCRL 248 K A+ITG ASGIG + EL+ +G V L D E++ + + G N L Sbjct: 9 KDATAIITGGASGIGRTMALELVSRGCTVVLADRQLVLAEELAASIVANGG--NAWAREL 66 Query: 249 DVTDYPQFEEAFVMTVEEFNRIDIVINNAGF----MNDRL----WELEVDVNLNGVIRGT 404 DV DYP ++ TV + R+D + NNAG M L W++ +DVN+ GV G Sbjct: 67 DVCDYPAYQALVDETVAKTGRLDYLFNNAGIAVGGMTHELEVNDWDMSLDVNVRGVTNGV 126 Query: 405 LLAYRFMGKDRGGQG-GVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVT 581 Y+ M + QG G IVNTAS A P + Y+ + +A+VGL++A + Sbjct: 127 QACYKLMVE----QGFGHIVNTASMAGLIPSTNAVPYSTSKFAVVGLSQAL--RIEAEYR 180 Query: 582 GVRCLVVCPG 611 GVR +CPG Sbjct: 181 GVRVSALCPG 190 >UniRef50_A3I6G4 Cluster: Putative 7-alpha-hydroxysteroid dehydrogenase; n=1; Bacillus sp. B14905|Rep: Putative 7-alpha-hydroxysteroid dehydrogenase - Bacillus sp. B14905 Length = 267 Score = 97.9 bits (233), Expect = 2e-19 Identities = 68/195 (34%), Positives = 98/195 (50%), Gaps = 12/195 (6%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 ++ KVAL+TG ASGIGL+ + L K+GAKV + D + E ++ L + + +F Sbjct: 4 VQNKVALVTGGASGIGLSAATLLAKEGAKVVIADFNIEGAQEAAHSLVKEGYEASAIF-- 61 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRL-----------WELEVDVNLNGV 392 LD D E A TVE++ + ++ NN G N + W+ V+VNL + Sbjct: 62 LDAGDASSIEAAVNFTVEQYGTLTVLFNNVGLTNLQKDLDVVNIDLDEWDRLVNVNLKSI 121 Query: 393 IRGTLLAYRFMGKDRGGQGGVIVNTAS-TAFARPQVSTPIYTATNYAIVGLTRAYGDQYH 569 + G+ A M K GG I+NTAS AFA Q+ T Y AT +V +T+ QY Sbjct: 122 LLGSRFAIPHMQK---AGGGSIINTASMAAFASDQIRT-AYGATKAGVVNMTKNIATQY- 176 Query: 570 VNVTGVRCLVVCPGL 614 +RC V PGL Sbjct: 177 -GKDKIRCNAVAPGL 190 >UniRef50_Q7MBD9 Cluster: 3-oxoacyl-(Acyl-carrier protein) reductase; n=17; Bacteria|Rep: 3-oxoacyl-(Acyl-carrier protein) reductase - Chromobacterium violaceum Length = 246 Score = 97.5 bits (232), Expect = 3e-19 Identities = 62/221 (28%), Positives = 113/221 (51%), Gaps = 8/221 (3%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLF 239 M LKGKV++ITG+ASGIG A +E+ +K+GA V++CD++ + + V ++L + G Sbjct: 1 MRLKGKVSIITGSASGIGKATAEKFVKEGAIVAVCDLNPDAVKTVVDELKALGG--EAYG 58 Query: 240 CRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF--------MNDRLWELEVDVNLNGVI 395 ++DVTD Q E RID+++NNAG M++ ++ +D+NL GV Sbjct: 59 YKVDVTDKGQIAEMVADLKNRCGRIDVLVNNAGIVQDAQLIKMSEDQFDKVIDINLKGVY 118 Query: 396 RGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVN 575 M ++G GGVI+N +S Y A + ++G + + + + Sbjct: 119 NCARAVVDTM-VEQG--GGVILNASSVVGVYGNFGQTNYAAAKFGVIGFVKTWAKE--LG 173 Query: 576 VTGVRCLVVCPGLTDSGLVXDLDKQLMSSKYETAWLEDITD 698 G+R VCPG + ++ + ++++ + + + + D Sbjct: 174 KKGIRANAVCPGFVATPILKAMPEKVLQAMEDKVPMRRMAD 214 >UniRef50_Q0LSE4 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Caulobacter sp. K31|Rep: Short-chain dehydrogenase/reductase SDR - Caulobacter sp. K31 Length = 277 Score = 97.1 bits (231), Expect = 4e-19 Identities = 72/219 (32%), Positives = 110/219 (50%), Gaps = 10/219 (4%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSER-GEQVTEKLASKYGRKNVLFC 242 L+GK+A++TGAA G+G A ++ L++GA V L D+ E+ E+ E A +GR Sbjct: 6 LQGKIAIVTGAARGLGAAIAKRYLEEGATVVLADLSEEKTTERAAELGAGAHGR------ 59 Query: 243 RLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRL--------WELEVDVNLNGVIR 398 R DV D+ F TV EF R+DI++NNAG L W+ + VN++ V Sbjct: 60 RCDVGDWEAFSTLIDATVAEFGRLDILVNNAGINRAGLVPGFSLQHWDDLLRVNVSSVFY 119 Query: 399 GTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNV 578 G A M R GG I+N AS A R + Y+A+ A+V TR+ H + Sbjct: 120 GCRAAIPHM---RRQGGGAIINVASIAGLRGETLAAAYSASKAAVVNFTRSLALD-HAD- 174 Query: 579 TGVRCLVVCPGLTDSGLVXDLDKQLMS-SKYETAWLEDI 692 +R +CPG ++ +++ +MS Y W++ I Sbjct: 175 ENIRVNAICPGSVET----EMNNLMMSRPDYIAQWIKTI 209 >UniRef50_A0QDR7 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase; n=2; Actinomycetales|Rep: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase - Mycobacterium avium (strain 104) Length = 250 Score = 97.1 bits (231), Expect = 4e-19 Identities = 69/190 (36%), Positives = 95/190 (50%), Gaps = 6/190 (3%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLF 239 M+ KVA++TGAASGIG A ++ L + GAKV + DI+ + GE+V ++A + G F Sbjct: 1 MNFTSKVAVVTGAASGIGEATAKRLAEDGAKVVVADINEDGGERVVAEIAERGG--EAAF 58 Query: 240 CRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMN--DRLWELEVDV--NLNGV-IRGT 404 R D++ V + + + NNA + L EL DV + G+ +RGT Sbjct: 59 LRTDISIEEDVNSLIDFAVSTYGGLHLAHNNAAVAHTPTPLHELSTDVFDTVTGIGLRGT 118 Query: 405 LLAYRF-MGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVT 581 R + G GG IVNTAS A + Y AT + IVGLTR G Y N Sbjct: 119 FFCMRAEIAHMIGHGGGAIVNTASGAALKAAAGMHAYVATKHGIVGLTRNAGLDYARN-- 176 Query: 582 GVRCLVVCPG 611 G+R V PG Sbjct: 177 GIRVNAVAPG 186 >UniRef50_Q88LI6 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family; n=2; Bacteria|Rep: Oxidoreductase, short chain dehydrogenase/reductase family - Pseudomonas putida (strain KT2440) Length = 262 Score = 96.7 bits (230), Expect = 5e-19 Identities = 70/210 (33%), Positives = 100/210 (47%), Gaps = 9/210 (4%) Frame = +3 Query: 51 SINMDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKN 230 ++N D GKV L+TGA SGIG A + + GA V++ DI ++ G + E + ++ G Sbjct: 2 TVNYDFSGKVVLVTGAGSGIGRATALAFAQSGASVAVADISTDHGLKTVELVKAEGG--E 59 Query: 231 VLFCRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF---------MNDRLWELEVDVNL 383 F +DV P + V + +DI NNAG ++ W +DVNL Sbjct: 60 ATFFHVDVGSEPSVQSMLAGVVAHYGGLDIAHNNAGIEANIVPLAELDSDNWRRVIDVNL 119 Query: 384 NGVIRGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQ 563 + V M K RG GG IVNTAS + YTAT + +VGLT+A Sbjct: 120 SSVFYCLKGEIPLMLK-RG--GGAIVNTASASGLIGGYRLSGYTATKHGVVGLTKAAAID 176 Query: 564 YHVNVTGVRCLVVCPGLTDSGLVXDLDKQL 653 Y N +R VCPG DS + D+ + + Sbjct: 177 Y-AN-QNIRINAVCPGPVDSPFLADMPQPM 204 >UniRef50_A1UMZ0 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=5; Mycobacterium|Rep: Short-chain dehydrogenase/reductase SDR precursor - Mycobacterium sp. (strain KMS) Length = 261 Score = 96.3 bits (229), Expect = 7e-19 Identities = 73/236 (30%), Positives = 107/236 (45%), Gaps = 10/236 (4%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLF 239 M L G+VAL+TG ASGIG A + L +G +V + DID E V E + + Sbjct: 1 MKLSGRVALVTGGASGIGRATAGRLAAEGMRVCVLDIDGPATEAVAESIGG-------IG 53 Query: 240 CRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMND----------RLWELEVDVNLNG 389 R DVTD Q + AF V E +D+ NAG D + V VN++G Sbjct: 54 LRCDVTDPEQVDSAFDTCVAELGGVDVAFLNAGITIDWSGDIGALDLAQYRKSVGVNVDG 113 Query: 390 VIRGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYH 569 V+ G A R M G I+ TAS A P P+Y+ + +VG R+ + Sbjct: 114 VVFGVRAAVRTMRTLDPGVDRAILATASLAGLMPWHPDPVYSLGKHGVVGFMRSIAP--N 171 Query: 570 VNVTGVRCLVVCPGLTDSGLVXDLDKQLMSSKYETAWLEDITDSKCRALITLGKPL 737 + G+ +CPG+T++G++ D + E I D+ L+ LG P+ Sbjct: 172 LAAEGIAVHTICPGITETGVLGDRRSLVERIGVPVMEPEMIADA---VLLALGAPM 224 >UniRef50_Q2NIC9 Cluster: Predicted short chain dehydrogenase; n=2; Euryarchaeota|Rep: Predicted short chain dehydrogenase - Methanosphaera stadtmanae (strain DSM 3091) Length = 253 Score = 96.3 bits (229), Expect = 7e-19 Identities = 66/215 (30%), Positives = 108/215 (50%), Gaps = 10/215 (4%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLF 239 M LKGKVA+ITGA +GIG + + ++GA L ER EQ+T ++ S G + Sbjct: 1 MKLKGKVAIITGATAGIGKSIAYLFAEEGASTILIARRKERLEQITNEINSNGGDASA-- 58 Query: 240 CRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFM---------NDRLWELEVDVNLNGV 392 C DVT + + ++++ +IDI++NNAG M +D LW+ +DVNL G Sbjct: 59 CIGDVTKQEDIDNVVKLALDKYGKIDIIVNNAGIMDDFVSVKHIDDDLWDKTIDVNLTGP 118 Query: 393 IRGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHV 572 +R M K+ GG I+ +S ++S YTA+ + ++GL + Y Sbjct: 119 MRLIRAVIPEMIKNNGGN---IITISSVGGLIGKISGAAYTASKHGVIGLAKHTAWVYGK 175 Query: 573 NVTGVRCLVVCPGLTDSGLVXDLDKQLMSSK-YET 674 + +R V+ PG ++ + ++ M + YET Sbjct: 176 H--NIRSNVIAPGTVNTEIATTINPGRMDMETYET 208 >UniRef50_O18404 Cluster: 3-hydroxyacyl-CoA dehydrogenase type-2; n=49; cellular organisms|Rep: 3-hydroxyacyl-CoA dehydrogenase type-2 - Drosophila melanogaster (Fruit fly) Length = 255 Score = 96.3 bits (229), Expect = 7e-19 Identities = 68/213 (31%), Positives = 108/213 (50%), Gaps = 17/213 (7%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 +K V+L+TG ASG+G A +E L KQGA V L D+ S +G +V ++L K V+F Sbjct: 2 IKNAVSLVTGGASGLGRATAERLAKQGASVILADLPSSKGNEVAKELGDK-----VVFVP 56 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAG---------FMNDRLWELE-----VDVNL 383 +DVT A ++F R+D+ +N AG F + LE +++N Sbjct: 57 VDVTSEKDVSAALQTAKDKFGRLDLTVNCAGTATAVKTFNFNKNVAHRLEDFQRVININT 116 Query: 384 NGVIRGTLLAYRFMG---KDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAY 554 G L+ MG ++ GQ GVIVNTAS A Q+ Y+A+ A+VG+T Sbjct: 117 VGTFNVIRLSAGLMGANEPNQDGQRGVIVNTASVAAFDGQIGQAAYSASKAAVVGMTLPI 176 Query: 555 GDQYHVNVTGVRCLVVCPGLTDSGLVXDLDKQL 653 ++ G+R + PGL ++ ++ L +++ Sbjct: 177 ARD--LSTQGIRICTIAPGLFNTPMLAALPEKV 207 >UniRef50_Q929J7 Cluster: Lin2278 protein; n=14; Bacteria|Rep: Lin2278 protein - Listeria innocua Length = 253 Score = 95.9 bits (228), Expect = 9e-19 Identities = 65/197 (32%), Positives = 97/197 (49%), Gaps = 9/197 (4%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 L GKVA++TGAASG+G + K+GAKV + D++ E ++ + + G L Sbjct: 4 LAGKVAVVTGAASGMGQQIAVLFAKEGAKVVVADLNLEAAQKTVALIEDEQG--TALAVV 61 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMN---------DRLWELEVDVNLNGVIR 398 +VT E E + +DI++NNAG M+ D LW+ +N GV+R Sbjct: 62 ANVTKQDDIESMINKATETYGTLDILVNNAGIMDNFVPAGELTDELWDKVFAINTTGVMR 121 Query: 399 GTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNV 578 T A + GQ GVIVN AS + YTA+ +A+VG T+ G QY N Sbjct: 122 ATRKALHIF--EEKGQ-GVIVNIASAGGLFGSRAGAAYTASKHAVVGFTKNVGFQY-AN- 176 Query: 579 TGVRCLVVCPGLTDSGL 629 +RC + PG ++ + Sbjct: 177 KNIRCNAIAPGAVNTNI 193 >UniRef50_A4ABB5 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Congregibacter litoralis KT71|Rep: Short-chain dehydrogenase/reductase SDR - Congregibacter litoralis KT71 Length = 253 Score = 95.9 bits (228), Expect = 9e-19 Identities = 67/198 (33%), Positives = 102/198 (51%), Gaps = 9/198 (4%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 LK KVAL+TG ASGIG + L++GA+V + DI+ E+G +V E+L+S ++ F Sbjct: 5 LKDKVALVTGGASGIGYETARSFLREGARVMIGDINLEQGRKVAEELSS---LGDIAFVE 61 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRL---------WELEVDVNLNGVIR 398 +VT + A TV+ F R+DI +NNAG + + W+ +++N+NGV Sbjct: 62 NNVTAEASCQNAVEHTVKRFGRLDIAVNNAGVIGETKPLLELSAEGWQRTMNININGVFF 121 Query: 399 GTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNV 578 G M GG I+N AS A S Y + +A+ GLT+A Y Sbjct: 122 GLKAQVNQM----LATGGSIINLASIASKIATPSCADYITSKHAVDGLTKAAALDY--AT 175 Query: 579 TGVRCLVVCPGLTDSGLV 632 G+R V PG+ ++ L+ Sbjct: 176 MGIRINSVGPGVIETPLL 193 >UniRef50_Q2FSZ0 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Methanospirillum hungatei JF-1|Rep: Short-chain dehydrogenase/reductase SDR - Methanospirillum hungatei (strain JF-1 / DSM 864) Length = 274 Score = 95.9 bits (228), Expect = 9e-19 Identities = 67/188 (35%), Positives = 93/188 (49%), Gaps = 8/188 (4%) Frame = +3 Query: 69 KGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCRL 248 +GKVA++TG SGIG A SEELLK+GA V + R E V + S KN F + Sbjct: 6 EGKVAIVTGGTSGIGYAVSEELLKRGATVW---VIGSRQESVDKARKSFAAYKNTRFLAV 62 Query: 249 DVTDYPQFEEAFVMTVEEFNRIDIVINNAG--------FMNDRLWELEVDVNLNGVIRGT 404 DVT Q + VE+ R+D + NNAG ++ +W+ +D+NL GV+ G Sbjct: 63 DVTVADQVKGMIDACVEKDGRLDYLFNNAGIGMTHPSQYLTLEMWQQAIDLNLWGVVYGV 122 Query: 405 LLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTG 584 A M + G IVNT+S A P S Y AT +A+ LT + +Y G Sbjct: 123 HFALPVMLAQKSGH---IVNTSSIAGIVPLPSQAAYCATKHAVTALTESL--RYEFFEEG 177 Query: 585 VRCLVVCP 608 + +CP Sbjct: 178 IAFTTICP 185 >UniRef50_Q9WYG0 Cluster: Uncharacterized oxidoreductase TM_0325; n=2; Thermotoga|Rep: Uncharacterized oxidoreductase TM_0325 - Thermotoga maritima Length = 251 Score = 95.9 bits (228), Expect = 9e-19 Identities = 68/193 (35%), Positives = 102/193 (52%), Gaps = 5/193 (2%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLF 239 M+ +GKV LITGA SGIG + ++GAKV++ DI E+G++ E + S G +F Sbjct: 1 MNFQGKVVLITGAGSGIGKKAAVMFAERGAKVAINDISEEKGKETVELIKSMGGEAAFIF 60 Query: 240 CRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMN----DRLWELEVDVNLNGVIRGTL 407 DV E+ TVE F R+DI++NNAG + + E + D + ++G Sbjct: 61 G--DVA--KDAEQIVKKTVETFGRLDILVNNAGIVPYGNIEETSEEDFDKTMAVNVKGPF 116 Query: 408 LAYRFMGKDRGGQ-GGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTG 584 L ++ + Q GGVIVN +S A +Y+ + A++GLTR+ Y V+ G Sbjct: 117 LLSKYAVEQMKKQGGGVIVNVSSEAGLIGIPRRCVYSVSKAALLGLTRSLAVDY-VDY-G 174 Query: 585 VRCLVVCPGLTDS 623 +R VCPG T S Sbjct: 175 IRVNAVCPGTTQS 187 >UniRef50_UPI0000E4700A Cluster: PREDICTED: hypothetical protein, partial; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: hypothetical protein, partial - Strongylocentrotus purpuratus Length = 246 Score = 95.5 bits (227), Expect = 1e-18 Identities = 69/233 (29%), Positives = 116/233 (49%), Gaps = 8/233 (3%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 L+GKVA++TGA+SGIG+ + EL K GA VSL E+ + V +++ G+ +F + Sbjct: 2 LQGKVAIVTGASSGIGIGIALELAKAGASVSLAARREEKLQDVKKEIEDVGGK--AMFVK 59 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF--------MNDRLWELEVDVNLNGVIRG 401 DVT Q ++ T EEF +DI++NNAG +++ WE +DVN GV+ G Sbjct: 60 TDVTVRQQVKDLIKKTEEEFGPVDILVNNAGIGYITYMKNLHEDAWEKMIDVNCKGVLNG 119 Query: 402 TLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVT 581 M + + G IVN +S A +YT T + + G++R+ + Sbjct: 120 IGAVLPGMMERKRGH---IVNISSNAGRAAFPLFAVYTGTKFFVEGVSRSLRMEVKDEGI 176 Query: 582 GVRCLVVCPGLTDSGLVXDLDKQLMSSKYETAWLEDITDSKCRALITLGKPLV 740 V C+ ++D G + DK+ + + D+ ++KC +G+ +V Sbjct: 177 KVTCIQAGDVISDFGDI-SFDKEALEA------YGDVDENKCMNPEDIGRAIV 222 >UniRef50_A7HWF2 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Alphaproteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Parvibaculum lavamentivorans DS-1 Length = 268 Score = 95.5 bits (227), Expect = 1e-18 Identities = 65/203 (32%), Positives = 104/203 (51%), Gaps = 11/203 (5%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 ++GKVA++TGAA GIG A ++ L ++GAKV D D+E G+ V +++A + G F R Sbjct: 4 MQGKVAIVTGAAKGIGAATAKALAREGAKVVCSDFDAENGQVVADEIAGEGG--TATFFR 61 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF------MNDRL---WELEVDVNLNGVIR 398 DVTD Q+E + E+F + +V+NNAG + ++ W ++V+L+ V Sbjct: 62 HDVTDEAQWEAVVKLAEEKFGGLHVVVNNAGIAPEAGPIEEKTLADWRHTIEVDLDSVFL 121 Query: 399 GTLLAYRFMGK--DRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHV 572 G R + K +GG GG IVN +S Q Y A + LT++ + Sbjct: 122 GCKHGIRTIKKYTSKGGAGGAIVNISSILGLVGQSGASDYNAAKGGVRLLTKSAALECAD 181 Query: 573 NVTGVRCLVVCPGLTDSGLVXDL 641 +R V PG D+ +V ++ Sbjct: 182 AGYNIRVNSVHPGYIDTPMVKNV 204 >UniRef50_A1T3E0 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Mycobacterium vanbaalenii PYR-1|Rep: Short-chain dehydrogenase/reductase SDR precursor - Mycobacterium vanbaalenii (strain DSM 7251 / PYR-1) Length = 286 Score = 95.1 bits (226), Expect = 2e-18 Identities = 71/194 (36%), Positives = 90/194 (46%), Gaps = 8/194 (4%) Frame = +3 Query: 54 INMDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNV 233 ++ +GKV ++TGAASGIGLA LL GA V L D D++R V E L GR V Sbjct: 2 VSNHFRGKVCVVTGAASGIGLAVGAALLDHGATVVLADFDADRLTTVAEGLCMHDGR--V 59 Query: 234 LFCRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMND--------RLWELEVDVNLNG 389 +DVT + +D + NNAG W VD+NL G Sbjct: 60 HSAVVDVTVQEAVQALVEGAARAHGSLDFLFNNAGVGGTMPIGVATLEQWRRIVDLNLWG 119 Query: 390 VIRGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYH 569 VI G A M + G IVNTAS A P +Y T Y +VGL+ + +Y Sbjct: 120 VIYGVHAAVPIMVRQGSGH---IVNTASLAGLVPFPYQSLYCTTKYGVVGLSESL--RYE 174 Query: 570 VNVTGVRCLVVCPG 611 + GVR VVCPG Sbjct: 175 LAADGVRVSVVCPG 188 >UniRef50_Q2J6E1 Cluster: Short-chain dehydrogenase/reductase SDR; n=6; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Frankia sp. (strain CcI3) Length = 277 Score = 94.7 bits (225), Expect = 2e-18 Identities = 67/204 (32%), Positives = 94/204 (46%), Gaps = 9/204 (4%) Frame = +3 Query: 48 SSINMDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRK 227 S + + KVAL+TGA SGIG A + L + GA+V D+D+ ++V + G Sbjct: 27 SLVMTECSDKVALLTGAGSGIGAACARRLARAGARVVATDLDAHTVKEVVATIED--GGG 84 Query: 228 NVLFCRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRL---------WELEVDVN 380 L DVTD E A +TV F R+D+ +NNAG R W+ +DVN Sbjct: 85 EALALEADVTDPDSLERAVQVTVGTFGRLDLAVNNAGVSAGREPVETTPAQDWQRVLDVN 144 Query: 381 LNGVIRGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGD 560 L+GV M + G GG IVN AS + Y A + ++GLT+ Sbjct: 145 LSGVFYSMRAEITAMLR---GDGGSIVNMASVLGVVGFAGSAPYVAAKHGVIGLTKTAAL 201 Query: 561 QYHVNVTGVRCLVVCPGLTDSGLV 632 Y G+R V PG D+ L+ Sbjct: 202 DYATR--GIRVNAVAPGFVDTPLL 223 >UniRef50_Q2GA84 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Novosphingobium aromaticivorans DSM 12444|Rep: Short-chain dehydrogenase/reductase SDR - Novosphingobium aromaticivorans (strain DSM 12444) Length = 310 Score = 94.7 bits (225), Expect = 2e-18 Identities = 70/217 (32%), Positives = 105/217 (48%), Gaps = 9/217 (4%) Frame = +3 Query: 63 DLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFC 242 +L GK A +TG ASGIGL ++ LL G V++ DI R + + +A G + VL Sbjct: 3 NLPGKTAFVTGGASGIGLGIAKALLGAGMNVTIADI---RQDHLDSAVAELGGGERVLAV 59 Query: 243 RLDVTDYPQFEEAFVMTVEEFNRIDIVINNAG--------FMNDRLWELEVDVNLNGVIR 398 +LDVT+ QF +A T +F +I +++NNAG W+ + VN+NG I Sbjct: 60 KLDVTNRDQFAKAADATEAKFGKIHLLVNNAGVAVVGPTELATFADWDWVMGVNVNGTIN 119 Query: 399 GTL-LAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVN 575 G + + R + G+GG IV TAS + P T IY+A A+ + + + Sbjct: 120 GIVTILPRILAH---GEGGHIVCTASMSALVPVAGTTIYSAGKAAVTAMMECMRPE--LE 174 Query: 576 VTGVRCLVVCPGLTDSGLVXDLDKQLMSSKYETAWLE 686 GV C CPG S + D K + +T + E Sbjct: 175 GRGVICSAFCPGAVQSN-IADAAKTRPAELADTGYAE 210 >UniRef50_Q0LQE1 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Herpetosiphon aurantiacus ATCC 23779|Rep: Short-chain dehydrogenase/reductase SDR precursor - Herpetosiphon aurantiacus ATCC 23779 Length = 254 Score = 94.3 bits (224), Expect = 3e-18 Identities = 65/209 (31%), Positives = 107/209 (51%), Gaps = 9/209 (4%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLF 239 M L V +ITGAASG+GLA + +GAK+ L D +++R E + + V+ Sbjct: 1 MRLHDNVVIITGAASGMGLAMATRFAAEGAKLVLGDWNAQRLEAAVATIQASGAA--VVG 58 Query: 240 CRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFM---------NDRLWELEVDVNLNGV 392 + ++ D E + + + ++D++ NNAG M +D +W + +NL G Sbjct: 59 AQGNIADQATAEALVDLAISSYGQLDVLCNNAGVMDSMQGVAEVSDDMWRRVLGINLEGP 118 Query: 393 IRGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHV 572 + + A ++M +RG GVIVN ASTA + YTA+ +A+VGLTR Y Sbjct: 119 MFTSRRALKYM-LERG--SGVIVNVASTAGIHGGSAGAAYTASKHALVGLTRNTAWIYAK 175 Query: 573 NVTGVRCLVVCPGLTDSGLVXDLDKQLMS 659 +RC +CPG T + +V +D+ ++ Sbjct: 176 R--NIRCNAICPGGTITNIVESMDRNAIA 202 >UniRef50_A6CQ13 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reductase; n=1; Bacillus sp. SG-1|Rep: 3-oxoacyl-(Acyl-carrier-protein) reductase - Bacillus sp. SG-1 Length = 246 Score = 94.3 bits (224), Expect = 3e-18 Identities = 61/202 (30%), Positives = 103/202 (50%), Gaps = 8/202 (3%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLF 239 M LK K A+ITG+A+GIGLA +++ ++G KV + D D +G EKL + G + +F Sbjct: 1 MRLKNKTAVITGSANGIGLAAAKKFAQEGCKVIMADYDENKGAAEAEKLQEEGG--DTVF 58 Query: 240 CRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRL--------WELEVDVNLNGVI 395 ++DV + + + ++ IDI+INNAG D L ++ +DVNL GV Sbjct: 59 YQVDVANRESVDNLAAWVLRDYGSIDILINNAGITRDALMAKMREDDFQRVLDVNLTGVF 118 Query: 396 RGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVN 575 T + G+ G I+NTAS + V Y A+ A++G+T+ + ++ Sbjct: 119 HCTQALLPAL--INSGK-GKIINTASASGLYGNVGQTNYAASKAAVIGMTKTWAKEF--G 173 Query: 576 VTGVRCLVVCPGLTDSGLVXDL 641 G+ V PG+ ++ + + Sbjct: 174 PKGINVNAVAPGVIETEMTASI 195 >UniRef50_A4B0K7 Cluster: Short-chain dehydrogenase/oxidoreductase; n=3; Bacteria|Rep: Short-chain dehydrogenase/oxidoreductase - Alteromonas macleodii 'Deep ecotype' Length = 295 Score = 94.3 bits (224), Expect = 3e-18 Identities = 68/226 (30%), Positives = 105/226 (46%), Gaps = 9/226 (3%) Frame = +3 Query: 63 DLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFC 242 + GK A+I+GAA GIGLA +E L +QG + + DID+ Q L K N+L C Sbjct: 4 EFNGKTAIISGAAGGIGLALAEALAEQGMNIVMGDIDNAALMQSGSALREK--GYNILTC 61 Query: 243 RLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF---------MNDRLWELEVDVNLNGVI 395 LDVTDY Q+E+ ++F ++ +VINNAG W +DVN+ GV+ Sbjct: 62 ALDVTDYSQWEDIVANAKDKFGKVHMVINNAGVGGTPGKVEDSEHETWRWVMDVNVMGVL 121 Query: 396 RGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVN 575 G + + G+GG ++N AS A Y A+ A+V +T ++ + + Sbjct: 122 YGAQASVPAI--QEHGEGGWVLNVASMAGMMGMPYAGAYCASKAAVVSMTESWIAE--LK 177 Query: 576 VTGVRCLVVCPGLTDSGLVXDLDKQLMSSKYETAWLEDITDSKCRA 713 + V+CP + + + KY A I K +A Sbjct: 178 PFNIHTSVLCPAFVKTRIHESYRNR--QQKYAVAQENRIDKEKLKA 221 >UniRef50_UPI000023E5B7 Cluster: hypothetical protein FG10672.1; n=1; Gibberella zeae PH-1|Rep: hypothetical protein FG10672.1 - Gibberella zeae PH-1 Length = 230 Score = 93.9 bits (223), Expect = 4e-18 Identities = 58/180 (32%), Positives = 96/180 (53%), Gaps = 11/180 (6%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 L+GK A++TG ASG G + + + +GA V + D++ + G+ V ++L N +F R Sbjct: 5 LQGKTAIVTGGASGFGKGIATKFIAEGANVVITDLNEQHGQAVAQEL-------NCVFSR 57 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF---------MNDRLWELEVDVNLNGVIR 398 D T + T+E+FN++DIV+NNAG + D+ ++L ++VN+ V Sbjct: 58 ADATSPDDWRHVLEFTLEKFNQLDIVVNNAGAAYPKKPTEQVTDKDFDLVMNVNVKSVYH 117 Query: 399 GT--LLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHV 572 T LL Y F+G GG+ G + ASTA RP+ Y A+ A++ T+ + H+ Sbjct: 118 STNVLLPY-FLG---GGRPGCFIQVASTAGIRPRPELTWYNASKAAVINATKTMAVETHL 173 >UniRef50_A4XEN1 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Novosphingobium aromaticivorans DSM 12444|Rep: Short-chain dehydrogenase/reductase SDR - Novosphingobium aromaticivorans (strain DSM 12444) Length = 253 Score = 93.9 bits (223), Expect = 4e-18 Identities = 60/193 (31%), Positives = 93/193 (48%), Gaps = 8/193 (4%) Frame = +3 Query: 57 NMDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVL 236 N + GKVAL+TG ASG+G + L ++GA+V + D+ + G++V ++ N + Sbjct: 6 NGQMDGKVALVTGGASGLGAEDARVLAREGARVVITDMQEDLGQKVASEI------PNCV 59 Query: 237 FCRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF-----MNDRLWE---LEVDVNLNGV 392 F + DV D ++ E T+ F R+D ++NNAG + D W+ L+ DV G Sbjct: 60 FLKQDVRDEARWGEVVAETLRLFGRLDTLVNNAGLVRFGTVEDLSWDDYKLQTDVMAGGT 119 Query: 393 IRGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHV 572 G A M KD G I+N AS + + P Y A I+G+TR+ Sbjct: 120 FLGCKAAIPHMSKDGSGS---IINMASVGGIKGISAIPAYAAAKAGIIGMTRSIAVHCRE 176 Query: 573 NVTGVRCLVVCPG 611 +RC + PG Sbjct: 177 QGYRIRCNSIAPG 189 >UniRef50_Q8YHE0 Cluster: GLUCOSE 1-DEHYDROGENASE II; n=4; Brucellaceae|Rep: GLUCOSE 1-DEHYDROGENASE II - Brucella melitensis Length = 272 Score = 93.5 bits (222), Expect = 5e-18 Identities = 64/202 (31%), Positives = 97/202 (48%), Gaps = 8/202 (3%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLF 239 M K KV ++TG ASGIG A + +++GAKV + D S+ G+Q+ ++LA + + LF Sbjct: 1 MRFKDKVVIVTGGASGIGEATARAFIREGAKVVIADF-SDHGQQLADELAGAH--EQALF 57 Query: 240 CRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF--------MNDRLWELEVDVNLNGVI 395 + DV D + TVE + R+DI+ NAG +++ W+ +D+NL GV Sbjct: 58 IKTDVADTRAVQALIARTVENYGRLDIMFANAGIAADAPIDELDEAAWQKTIDINLTGVY 117 Query: 396 RGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVN 575 A M R GGVIVN S + Y A + LT+ Y Sbjct: 118 LCDKYAIDQM---RSQGGGVIVNCGSIHSHVGKSGVTAYAAAKGGVKLLTQTLAIDY--G 172 Query: 576 VTGVRCLVVCPGLTDSGLVXDL 641 +R VCPG D+ L+ ++ Sbjct: 173 PQNIRVNAVCPGYIDTPLLKNI 194 >UniRef50_Q6LH36 Cluster: Hypothetical oxidoreductase, short-chain dehydrogenase/reductase family; n=1; Photobacterium profundum|Rep: Hypothetical oxidoreductase, short-chain dehydrogenase/reductase family - Photobacterium profundum (Photobacterium sp. (strain SS9)) Length = 255 Score = 93.5 bits (222), Expect = 5e-18 Identities = 72/217 (33%), Positives = 104/217 (47%), Gaps = 13/217 (5%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 L GKVALI+G SGIG A + +QGA + L + +G+ + E+L ++Y LF + Sbjct: 7 LAGKVALISGITSGIGEATARLFSQQGASLVLVARNENKGQMLAEELNAQY---PTLFIK 63 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF---------MNDRLWELEVDVNLNGVIR 398 D+T Q ++ F T+ EF ID NNAG +D +W ++ NLNG Sbjct: 64 ADITQANQVDQVFEQTMAEFGGIDCAFNNAGIDGSKQPISETSDEIWNQIINTNLNGTWN 123 Query: 399 GTLLAYRFMGKDRGGQG-GVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVN 575 M K QG G IVN AS + + Y + +A++GLTR+ +Y Sbjct: 124 MLNRQLSIMSK----QGHGTIVNMASICSVLARPNRAAYNTSRHAVLGLTRSAAVEYAKQ 179 Query: 576 VTGVRCLVVCPGLTDSGLV---XDLDKQLMSSKYETA 677 GVR V PG D+ + D QL+ +KY A Sbjct: 180 --GVRVNAVAPGAIDTPIFERSTQKDPQLI-AKYHQA 213 >UniRef50_A0Z5Q6 Cluster: Short chain dehydrogenase; n=1; marine gamma proteobacterium HTCC2080|Rep: Short chain dehydrogenase - marine gamma proteobacterium HTCC2080 Length = 251 Score = 93.5 bits (222), Expect = 5e-18 Identities = 65/199 (32%), Positives = 98/199 (49%), Gaps = 9/199 (4%) Frame = +3 Query: 63 DLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFC 242 +LKGKVA++TG +GIGLA + L + G V + DIDS Q L S+ G + V Sbjct: 4 ELKGKVAVVTGGGAGIGLACAARLAEAGVAVGVADIDSAAAHQAAADLTSQ-GHRCVAIV 62 Query: 243 RLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF---------MNDRLWELEVDVNLNGVI 395 DV+ + E+ F +T E F I+I +NNAG + ++ + VNL GV Sbjct: 63 -TDVSKAKEVEKLFQITNEAFGPINIAVNNAGVGAPLTPLGDTEEEDFDRVMAVNLKGVW 121 Query: 396 RGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVN 575 A R M + G I+N AS + +YTA+ + + GLTR+ +Y Sbjct: 122 LCMRAALRHMAPQKSGS---IINMASALSTTTFPGSGLYTASKHGVAGLTRSAAVEY--G 176 Query: 576 VTGVRCLVVCPGLTDSGLV 632 +G+R +CPG + L+ Sbjct: 177 ESGIRINAICPGFISTPLL 195 >UniRef50_Q8F682 Cluster: 3-oxoacyl-(Acyl carrier protein) reductase; n=4; Leptospira|Rep: 3-oxoacyl-(Acyl carrier protein) reductase - Leptospira interrogans Length = 256 Score = 93.1 bits (221), Expect = 7e-18 Identities = 62/198 (31%), Positives = 104/198 (52%), Gaps = 6/198 (3%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 +K KVA++TG ++GIG A +E + +G KV C E G+++ ++ ++ G +V F Sbjct: 5 MKDKVAIVTGGSTGIGKAVVKEFVSKGVKVVFCGRRLEEGKKLESEIRAEGG--DVYFVV 62 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFM--NDRLWELEVDV---NLNGVIRGTLL 410 DVT Q ++ +E+F R+D INNAG M N L E DV +N ++GT L Sbjct: 63 CDVTSGEQVKKVVDAALEKFGRLDFGINNAGIMGLNHLLHEYPEDVWDKVVNVNLKGTWL 122 Query: 411 AYRFMGKDRGGQ-GGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTGV 587 + ++ + GGV+VN +S + V Y A + +VGLT++ +Y + Sbjct: 123 SMKYQIPEMIKMGGGVVVNVSSISGINGVVGINPYAAAKHGVVGLTKSAALEYAKK--NI 180 Query: 588 RCLVVCPGLTDSGLVXDL 641 R +CPG + ++ +L Sbjct: 181 RINAICPGAVKTEILDEL 198 >UniRef50_A1UEP6 Cluster: Short-chain dehydrogenase/reductase SDR; n=18; Actinomycetales|Rep: Short-chain dehydrogenase/reductase SDR - Mycobacterium sp. (strain KMS) Length = 257 Score = 93.1 bits (221), Expect = 7e-18 Identities = 70/203 (34%), Positives = 100/203 (49%), Gaps = 11/203 (5%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 LKGKVA+ITG ASGIGLA ++ + +GA + + DID G+ V + L N F + Sbjct: 7 LKGKVAVITGGASGIGLATAKRMRAEGATIVIGDIDPATGKTVADDL-------NGTFVQ 59 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFM--NDRL--------WELEVDVNLNGVI 395 +DV+D + F EE +DI NNAG D L W+ D+NL V Sbjct: 60 VDVSDQVAVDALFDTAAEEHGSVDIAFNNAGISPPEDDLIEVTGIDAWDRVQDINLKSVF 119 Query: 396 RGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPI-YTATNYAIVGLTRAYGDQYHV 572 A R M Q G I+NTAS ++ I YTA+ ++ ++R G QY Sbjct: 120 FCCKAALRHMVP---AQKGSIINTASFVAVNGSATSQISYTASKGGVLAMSRELGIQYAR 176 Query: 573 NVTGVRCLVVCPGLTDSGLVXDL 641 G+R +CPG ++ L+ +L Sbjct: 177 Q--GIRVNALCPGPVNTPLLQEL 197 >UniRef50_Q9UY54 Cluster: Short-chain alcohol dehydrogenase, putative glucose-1-dehydrogenase; n=1; Pyrococcus abyssi|Rep: Short-chain alcohol dehydrogenase, putative glucose-1-dehydrogenase - Pyrococcus abyssi Length = 240 Score = 93.1 bits (221), Expect = 7e-18 Identities = 69/208 (33%), Positives = 104/208 (50%), Gaps = 9/208 (4%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLF 239 M+LKGKVALITGA+ GIG A + EL K+G V + +E + TE+L +YG + +L Sbjct: 1 MELKGKVALITGASRGIGRAIAIELAKRGVNVVINYRSNEEEAKKTEELCRQYGVETLL- 59 Query: 240 CRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFM---------NDRLWELEVDVNLNGV 392 + DV++ + E +++F RIDI+INNAG + D W+ + VNL G Sbjct: 60 VKADVSNREEVREMVKKVIDKFGRIDILINNAGILGKTKDPLEVTDEEWDRVISVNLKGA 119 Query: 393 IRGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHV 572 T R+M K G IVN AS A P Y A+ ++ LT + H+ Sbjct: 120 FIVTQEVLRYMKK------GKIVNIASIAGKDGGTVGPHYAASKGGLIALT--FNLARHL 171 Query: 573 NVTGVRCLVVCPGLTDSGLVXDLDKQLM 656 + V PG D+ ++ K+++ Sbjct: 172 -APNILVNAVAPGPVDTDMLSSEMKEML 198 >UniRef50_Q8R9W0 Cluster: Dehydrogenases with different specificities; n=4; Bacteria|Rep: Dehydrogenases with different specificities - Thermoanaerobacter tengcongensis Length = 247 Score = 92.7 bits (220), Expect = 9e-18 Identities = 61/202 (30%), Positives = 101/202 (50%), Gaps = 9/202 (4%) Frame = +3 Query: 75 KVALITGAASGIGLAYSEELLKQGAKVSLCDI-DSERGEQVTEKLASKYGRKNVLFCRLD 251 +VA +TG + GIG A + L K G +++ + D + E+V E++ K+G + L + D Sbjct: 6 RVAFVTGGSRGIGRAIAVRLAKDGFNIAITYVKDDKSAEEVVEEV-KKHG-VDALAIKCD 63 Query: 252 VTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRL--------WELEVDVNLNGVIRGTL 407 V+ Y + E+A +EEF ID+V+NNAG D L W+ +DVNL G Sbjct: 64 VSKYHEVEKAVEKVIEEFGSIDVVVNNAGITKDNLILKMEEEEWDQVIDVNLKGAFNVIK 123 Query: 408 LAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTGV 587 A ++M K R G+ I+N +S V Y A+ I+GLT++ + + G+ Sbjct: 124 FASKYMIKKRKGK---IINISSVVGLMGNVGQANYAASKAGIIGLTKSVAKE--LASRGI 178 Query: 588 RCLVVCPGLTDSGLVXDLDKQL 653 V PG ++ + L + + Sbjct: 179 TVNAVAPGFIETDMTNVLKEDI 200 >UniRef50_Q8ELN8 Cluster: Glucose 1-dehydrogenase; n=6; cellular organisms|Rep: Glucose 1-dehydrogenase - Oceanobacillus iheyensis Length = 256 Score = 92.7 bits (220), Expect = 9e-18 Identities = 59/213 (27%), Positives = 104/213 (48%), Gaps = 9/213 (4%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 L+ KVA++TGAA G+G A + + AKV + D + E+G++V E++ G+ F + Sbjct: 6 LEDKVAIVTGAAMGMGKATAILFAESKAKVVIADFNEEKGQEVVEEVKQAGGQ--AAFIK 63 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF---------MNDRLWELEVDVNLNGVIR 398 +D++D Q ++ V++F ++DI +NNA ++ W+ + V+L G Sbjct: 64 VDISDSAQVKQMVQFAVDQFGKLDIAVNNAALTPDDKPASEFDEDYWDKLISVDLTGT-- 121 Query: 399 GTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNV 578 + Y G GG IVN +S + RPQ + Y A + +VG+T+ Sbjct: 122 ALCMKYELQQLLEQGNGGSIVNISSVSGFRPQPNNIAYVAAKHGVVGMTKVAA--LENGP 179 Query: 579 TGVRCLVVCPGLTDSGLVXDLDKQLMSSKYETA 677 +R V PG D+ ++ +Q ++ E A Sbjct: 180 QNIRVNTVAPGAIDTPMLRGALEQFNHTEEEYA 212 >UniRef50_A0H5N7 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Chloroflexus|Rep: Short-chain dehydrogenase/reductase SDR - Chloroflexus aggregans DSM 9485 Length = 256 Score = 92.7 bits (220), Expect = 9e-18 Identities = 68/199 (34%), Positives = 98/199 (49%), Gaps = 8/199 (4%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLF 239 M+ +GKVA++TG A GIG A + L ++GA V + D D+ + E + + GR L Sbjct: 1 MEFQGKVAIVTGGAQGIGRATALALAREGAAVVIADRDAAATTALVEGINAWGGR--ALA 58 Query: 240 CRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMND--------RLWELEVDVNLNGVI 395 DV+D TV EF ID+++NNAG +LW+ ++VNL GV Sbjct: 59 VIADVSDESDAARIANDTVLEFGGIDLLVNNAGIQQPGTIESTTLQLWQEIINVNLTGVF 118 Query: 396 RGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVN 575 L++ M + R GG IVN AS R + Y A+ ++ LTRA Sbjct: 119 ---LVSRFVMPELRRRGGGAIVNVASVYGLRAEAGWAAYAASKGGVIALTRAMA--LDGA 173 Query: 576 VTGVRCLVVCPGLTDSGLV 632 G+R VCPGL D+ L+ Sbjct: 174 PDGIRVNCVCPGLIDTSLL 192 >UniRef50_Q5P686 Cluster: Subunit of 2-[hydroxy(Phenyl)methyl]-succinyl-CoA DH; n=4; Proteobacteria|Rep: Subunit of 2-[hydroxy(Phenyl)methyl]-succinyl-CoA DH - Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum (strain EbN1)) Length = 248 Score = 92.3 bits (219), Expect = 1e-17 Identities = 69/224 (30%), Positives = 116/224 (51%), Gaps = 11/224 (4%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLF 239 M ++ +VAL+TG+ASG+G + ++GA V + DID+E+ ++ S+ G + VL Sbjct: 1 MGIQNRVALVTGSASGMGKQTALRFAERGAAVVINDIDAEKVRTTVDEF-SRLGHR-VLG 58 Query: 240 CRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF--------MNDRLWELEVDVNLNGVI 395 D+++ + TVE F RIDI++NNAG +++ W++ VDVNL G Sbjct: 59 TVADISNKAAVDGMVQQTVEAFGRIDILVNNAGMERAGALRKLSEADWDITVDVNLKGTF 118 Query: 396 RGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVN 575 T + M +++ G+ IVN AS A+ TP Y++ +VG+TRA + Sbjct: 119 LCTQAVHGHMVENKHGR---IVNIASRAWLGGAGQTP-YSSAKAGVVGMTRALA--IELG 172 Query: 576 VTGVRCLVVCPGLTDSGLVXDL---DKQLMSSKYETAWLEDITD 698 +G+ V PGL + + +L D+ + S+ T L + D Sbjct: 173 RSGITVNCVAPGLIHTPMWEELPEKDRNFLLSRQPTGKLGEPDD 216 >UniRef50_A6W2Y5 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Marinomonas sp. MWYL1|Rep: Short-chain dehydrogenase/reductase SDR - Marinomonas sp. MWYL1 Length = 252 Score = 91.9 bits (218), Expect = 2e-17 Identities = 69/197 (35%), Positives = 97/197 (49%), Gaps = 9/197 (4%) Frame = +3 Query: 63 DLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDID-SERGEQVTEKLASKYGRKNVLF 239 DL KV L+TGA+ GIG A +E L + GA V +CD+ E+G + K GRK +F Sbjct: 3 DLTNKVVLVTGASRGIGRALAEGLAEHGADVVICDLPREEKGLNEAKSAIEKLGRKCWVF 62 Query: 240 CRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRLWE--LEVDVNLNGVIRGTLLA 413 D+TD E E+ ID+++NNAG + L E E D + + + G L Sbjct: 63 -GADITDKSAVENMVAQATEQAGHIDVLVNNAGILKPSLLEDLSEGDWDAHFAVNGKGLL 121 Query: 414 Y---RFMGKDRGGQGGVIVNTASTAFARPQVSTP-IYTATNYAIVGLTRAYGDQYHVNVT 581 + + + R + G I+N AS A AR V T Y AT V LTR Y + + Sbjct: 122 FVTNAVLPQMRQRKNGRIINIASIA-ARQGVPTQGHYAATKATAVTLTRVYAQE--TGMD 178 Query: 582 GVRCLVVCPG--LTDSG 626 G+ +CPG LT+ G Sbjct: 179 GITVNAICPGIILTEMG 195 >UniRef50_A3Q331 Cluster: Short-chain dehydrogenase/reductase SDR; n=10; Mycobacterium|Rep: Short-chain dehydrogenase/reductase SDR - Mycobacterium sp. (strain JLS) Length = 282 Score = 91.9 bits (218), Expect = 2e-17 Identities = 60/174 (34%), Positives = 90/174 (51%), Gaps = 10/174 (5%) Frame = +3 Query: 57 NMDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVL 236 N +L+G+VA++TG ASGIG +E + +GAKV + D+ E GE + E+ N L Sbjct: 6 NDELQGRVAIVTGGASGIGRGVAERFVAEGAKVVIADVQDELGEALAEQCG-----PNAL 60 Query: 237 FCRLDVTDYPQFEEAFVMTVEEFNRIDIVINNA--------GFMNDRLWELE--VDVNLN 386 F DV D Q + VE F +D+++NNA G N+ L E + + VNL Sbjct: 61 FHHTDVGDQEQMRRLVDVAVERFGALDVMVNNAGISSPLRRGLFNEDLEEFDRVMRVNLL 120 Query: 387 GVIRGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTR 548 V+ GT A R+M + GG I+N +S + P+Y A+ AI+ T+ Sbjct: 121 SVMAGTRDAGRYMSEHGGGS---IINLSSIGGIQAGGGVPVYRASKAAILHFTK 171 >UniRef50_A0YFJ9 Cluster: Putative uncharacterized protein; n=1; marine gamma proteobacterium HTCC2143|Rep: Putative uncharacterized protein - marine gamma proteobacterium HTCC2143 Length = 297 Score = 91.9 bits (218), Expect = 2e-17 Identities = 61/191 (31%), Positives = 95/191 (49%), Gaps = 9/191 (4%) Frame = +3 Query: 63 DLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFC 242 D GK+A +TGAASGIGL + + +G KV + DI++ E L + + C Sbjct: 3 DFDGKIAFVTGAASGIGLGITRAFVAKGMKVMMADIEAGPLESAVASLREQGADVAGVIC 62 Query: 243 RLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF---------MNDRLWELEVDVNLNGVI 395 DV+D + A T+E F ++ +++NNAG + W+ VDVNL GV+ Sbjct: 63 --DVSDVEAVKLAAEKTIETFGKVHVIVNNAGVGGGGGETGTIPIEDWKWTVDVNLMGVV 120 Query: 396 RGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVN 575 G + + + G+GG I+NTAS A V Y AT +A+VG + + + + Sbjct: 121 YGCEIFVPLIKEH--GEGGYIINTASLAGQVGTVGMGPYNATKFAVVGYSESMNSE--LV 176 Query: 576 VTGVRCLVVCP 608 G+ V+CP Sbjct: 177 PQGIGVAVLCP 187 >UniRef50_A0Y8J3 Cluster: Short chain dehydrogenase; n=1; marine gamma proteobacterium HTCC2143|Rep: Short chain dehydrogenase - marine gamma proteobacterium HTCC2143 Length = 279 Score = 91.9 bits (218), Expect = 2e-17 Identities = 62/199 (31%), Positives = 100/199 (50%), Gaps = 10/199 (5%) Frame = +3 Query: 63 DLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFC 242 D+ G+VA ITGAASGIG + ++ +GAK+ + D ++E ++ L + + C Sbjct: 3 DITGRVAFITGAASGIGYSLAKSFAARGAKIMMADRNAETLQRAENDLRATGADVASVVC 62 Query: 243 RLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF----------MNDRLWELEVDVNLNGV 392 DVT + A T++ F ++ IV NNAG M D W +D+N+ GV Sbjct: 63 --DVTSLDSMKAAAQATLDRFAKVHIVANNAGVPMGGKPGRIPMED--WRWVLDINVIGV 118 Query: 393 IRGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHV 572 G + + + G+GG +NTAS A Q Y A+ +A+VG + + D+ Sbjct: 119 AHGVEVFTPILREQ--GEGGHFLNTASMAGLMGQAGVAPYVASKFAVVGYSESLRDEVAT 176 Query: 573 NVTGVRCLVVCPGLTDSGL 629 + GV V+CPG ++G+ Sbjct: 177 DNIGVS--VLCPGYVNTGI 193 >UniRef50_Q5WBM0 Cluster: Oxidoreductase; n=1; Bacillus clausii KSM-K16|Rep: Oxidoreductase - Bacillus clausii (strain KSM-K16) Length = 247 Score = 91.5 bits (217), Expect = 2e-17 Identities = 67/199 (33%), Positives = 101/199 (50%), Gaps = 8/199 (4%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLF 239 ++L KV +ITG ASGIG A + L +GAKV + D + E GE ++L K VLF Sbjct: 2 VELTNKVVIITGGASGIGRAAVDAFLAKGAKVVIADFNKETGEAAVKELTD--AGKQVLF 59 Query: 240 CRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF-----MNDRL---WELEVDVNLNGVI 395 + DV++ P + TV+ + R+DI+INNAGF ++R +E V V +GV Sbjct: 60 VQTDVSNEPSVQNMVAETVKAYERVDILINNAGFGTMSPSHERTYEDYEKIVKVCQDGVF 119 Query: 396 RGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVN 575 G+ A + M K GG I+NT+S + Q Y A A+ +T++ +Y Sbjct: 120 LGSKHAIKEMIKT---GGGCIINTSSILGSVAQPEALPYNAAKGAVNTMTKSLAVEYADK 176 Query: 576 VTGVRCLVVCPGLTDSGLV 632 +R V PG ++ V Sbjct: 177 --QIRVNAVAPGFVETAAV 193 >UniRef50_Q3M1E6 Cluster: NAD-dependent epimerase/dehydratase precursor; n=3; Cyanobacteria|Rep: NAD-dependent epimerase/dehydratase precursor - Anabaena variabilis (strain ATCC 29413 / PCC 7937) Length = 251 Score = 91.5 bits (217), Expect = 2e-17 Identities = 69/196 (35%), Positives = 98/196 (50%), Gaps = 6/196 (3%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLF 239 M LK KVAL+TG SGIG A + KQ AKV + + GE+ T +L + G + F Sbjct: 1 MMLKDKVALVTGGTSGIGRATAIAYAKQQAKVVVVGRRIDEGEE-TVRLIQEAGGE-AFF 58 Query: 240 CRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDR-----LWELEVDVNLNGVIRGT 404 + DVT + V F R+DI NNAG + + E E D +N ++G Sbjct: 59 VQSDVTKEADVKAMVDKAVGVFGRLDIAFNNAGMVGENPSLIEQTEAEYDRIMNVNVKGV 118 Query: 405 LLAYRFMGKDRGGQG-GVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVT 581 L+ ++ QG G IVNT+S A P+YTA+ +A+VGLT+A QY Sbjct: 119 WLSMKYEIAQMLKQGSGAIVNTSSGAGVVALPGVPLYTASKHAVVGLTKAAALQY--AKA 176 Query: 582 GVRCLVVCPGLTDSGL 629 G+R V PG ++ + Sbjct: 177 GIRINAVAPGSIETDM 192 >UniRef50_Q7VXT8 Cluster: Probable short-chain dehydrogenase; n=3; Bordetella|Rep: Probable short-chain dehydrogenase - Bordetella pertussis Length = 252 Score = 91.1 bits (216), Expect = 3e-17 Identities = 67/189 (35%), Positives = 95/189 (50%), Gaps = 7/189 (3%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 L G+ ALITGAA GIG A + +GA V L DID+ERG+ + +LA+ R F R Sbjct: 4 LSGRNALITGAAVGIGAAMARRFCAEGASVLLGDIDAERGQALAAELAATGARAR--FAR 61 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAG--FMNDR-LWELEVDV---NLNGVIRGTL 407 LDVTD +A + E + I++NNAG +NDR + E ++ +N + GT+ Sbjct: 62 LDVTDEDSVRQAMELAEAEHGPLHILVNNAGGSSLNDRSVVEFALEEFWRAINIDLLGTV 121 Query: 408 LAYRF-MGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTG 584 L R + + GG +VN S A R YTA + LTR+ ++ Sbjct: 122 LCCRHAIPRIAAAGGGAVVNMGSIAALRGLKGRDAYTAAKGGVHALTRSMAVEFAEQ--R 179 Query: 585 VRCLVVCPG 611 VRC + PG Sbjct: 180 VRCNAIAPG 188 >UniRef50_A2U8H9 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Bacillus coagulans 36D1|Rep: Short-chain dehydrogenase/reductase SDR - Bacillus coagulans 36D1 Length = 262 Score = 91.1 bits (216), Expect = 3e-17 Identities = 62/200 (31%), Positives = 99/200 (49%), Gaps = 6/200 (3%) Frame = +3 Query: 63 DLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFC 242 D GKVA++TG GIG +L GA V + D+ E GE+ K+ G +F Sbjct: 5 DFTGKVAIVTGGGGGIGREACLKLAAGGANVVVADLSDELGEETAGKIRENGG--EAIFV 62 Query: 243 RLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF---MNDRL-WELEVDVNLNGV-IRGTL 407 R DV+ + ++ + +IDI++NNAG+ M + + EV L G+ +RG Sbjct: 63 RTDVSKSKDVQHYVRTALDTYGKIDILLNNAGWEGKMKPLIDYPEEVFDKLMGINVRGVF 122 Query: 408 LAYRFMGKDRGGQ-GGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTG 584 L +++ Q G IVNTAS A Y A+ +A++G+T+ G +G Sbjct: 123 LGMKYVLPHMISQKSGTIVNTASVAGLVGTPEMVAYGASKHAVIGMTKTAG--IEAAPSG 180 Query: 585 VRCLVVCPGLTDSGLVXDLD 644 VR VCPG+ D+ ++ ++ Sbjct: 181 VRVNAVCPGVVDTEMMRKIE 200 >UniRef50_A7EQI6 Cluster: Putative uncharacterized protein; n=1; Sclerotinia sclerotiorum 1980|Rep: Putative uncharacterized protein - Sclerotinia sclerotiorum 1980 Length = 249 Score = 91.1 bits (216), Expect = 3e-17 Identities = 59/195 (30%), Positives = 98/195 (50%), Gaps = 7/195 (3%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 LK KVA++TG SG G A + +G KV++ DID+ GE+V + ++LF + Sbjct: 14 LKNKVAIVTGGGSGFGEAIARRFAGEGCKVTIADIDAVGGERV-----ANVHPHSMLFVK 68 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAG--FMNDRLWEL---EVDVNLNGVIRGTLL 410 +DVT+ +E T+ ++ R+D+ +NNAG + N ++ E D N ++ Sbjct: 69 MDVTNEEDWERVLETTLAKWGRVDVCVNNAGTSYRNKPTLDVIEDEFDKVFNVNVKSIFY 128 Query: 411 AYRFMGKD--RGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTG 584 A R + G+GG ++N AS +RP+ Y A+ A+V T+ +Y Sbjct: 129 ATRHFIPNVINQGEGGSMINIASIGASRPRAGLVWYNASKAAVVNATKGLAAEY--GPKN 186 Query: 585 VRCLVVCPGLTDSGL 629 +R +CP L +GL Sbjct: 187 IRINSICPLLAGTGL 201 >UniRef50_Q9K636 Cluster: 3-oxoacyl-(Acyl-carrier protein) reductase; n=17; Bacteria|Rep: 3-oxoacyl-(Acyl-carrier protein) reductase - Bacillus halodurans Length = 246 Score = 90.6 bits (215), Expect = 4e-17 Identities = 64/217 (29%), Positives = 105/217 (48%), Gaps = 9/217 (4%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLAS-KYGRKNVL 236 M L GKVA+ITGA GIG A +++ ++GAKV +CD+ R E+V + +A + G L Sbjct: 1 MRLNGKVAMITGAGRGIGAATAKKFAREGAKVIVCDV---REEEVAKTVAEIQDGGGEAL 57 Query: 237 FCRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF--------MNDRLWELEVDVNLNGV 392 +DVT + +E F +D+V+NNAG M D W+ +DVNL GV Sbjct: 58 GSVVDVTQRKDVKNVINQVIERFETLDVVVNNAGITADAQLTNMTDAQWDDVIDVNLKGV 117 Query: 393 IRGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHV 572 T M + + GVI+N +S + Y A+ + + G+T+ + + + Sbjct: 118 FIVTQEVTTIMKEQK---RGVILNASSVVGSYGNFGQTNYAASKWGVNGMTKTWAKE--L 172 Query: 573 NVTGVRCLVVCPGLTDSGLVXDLDKQLMSSKYETAWL 683 +R V PG + + + ++++ E A L Sbjct: 173 GRYNIRVNAVAPGFILTPMTEKMPEKVLKVMEEKAVL 209 >UniRef50_A3CU09 Cluster: Short-chain dehydrogenase/reductase SDR; n=5; cellular organisms|Rep: Short-chain dehydrogenase/reductase SDR - Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1) Length = 249 Score = 90.6 bits (215), Expect = 4e-17 Identities = 62/203 (30%), Positives = 95/203 (46%), Gaps = 8/203 (3%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 ++ KV +ITG+ SGIG A ++++ +G KV + + + G ++ ++ G V+F R Sbjct: 4 MENKVCVITGSTSGIGEACAKDMAAEGGKVVVSGRNEKEGARIVNEIKEAGG--EVIFIR 61 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF--------MNDRLWELEVDVNLNGVIRG 401 DVT TVE F R+D+ + N+G + W+ +DVNL G+ Sbjct: 62 ADVTVEDDVRNLVAKTVEAFGRLDVFVANSGVGSLGDPHEVETEEWDRVLDVNLKGIFLC 121 Query: 402 TLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVT 581 A + M K GQGG IVNT S + Y A + LTR G Y Sbjct: 122 DKYAVQQMLKQ--GQGGAIVNTGSIHSFVAKQGVTAYGAAKGGVAMLTRTLGTSYAAQ-- 177 Query: 582 GVRCLVVCPGLTDSGLVXDLDKQ 650 G+R V PG D+ L+ L ++ Sbjct: 178 GIRANFVAPGYIDTPLLAALPRE 200 >UniRef50_Q5QW23 Cluster: 3-oxoacyl-(Acyl carrier protein) reductase, putative; n=26; Gammaproteobacteria|Rep: 3-oxoacyl-(Acyl carrier protein) reductase, putative - Idiomarina loihiensis Length = 254 Score = 90.2 bits (214), Expect = 5e-17 Identities = 64/212 (30%), Positives = 107/212 (50%), Gaps = 18/212 (8%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLF 239 M +K V +ITG A G+GLA +E+ +QGAK++L DI+ + + E+ K G V+ Sbjct: 1 MQIKDSVIVITGGAQGLGLAMAEDFARQGAKLALIDINGDVLGEAQEQ-CEKLGAAKVVG 59 Query: 240 CRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRL-----------------WELE 368 +D+TD E F +EF+ ID+++NNAG + D L ++ Sbjct: 60 YEVDITDEESVETVFEQIQQEFDGIDVLVNNAGLLRDGLLIKFKDGELKQKMPLQQFQSV 119 Query: 369 VDVNLNGV-IRGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLT 545 +DVNL G + G A + + + G+ GVI+N +S A A T Y+AT +V +T Sbjct: 120 LDVNLTGTFLCGREAAAQMV---KAGKKGVIINISSVARAGNMGQTN-YSATKAGVVAMT 175 Query: 546 RAYGDQYHVNVTGVRCLVVCPGLTDSGLVXDL 641 + + + G+RC + PG ++ + + Sbjct: 176 VTWARE--LGRYGIRCGAIAPGFIETPMTAQM 205 >UniRef50_Q0M0K7 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Caulobacter sp. K31|Rep: Short-chain dehydrogenase/reductase SDR - Caulobacter sp. K31 Length = 249 Score = 90.2 bits (214), Expect = 5e-17 Identities = 64/200 (32%), Positives = 102/200 (51%), Gaps = 8/200 (4%) Frame = +3 Query: 54 INMDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNV 233 ++MDL G+VAL+TGA+SG G A + +L K GAKV+L +R + +++ G+ V Sbjct: 1 MSMDLSGRVALVTGASSGFGEAVALDLAKAGAKVALAARREDRLRALAQRITDAGGQAQV 60 Query: 234 LFCRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFM--------NDRLWELEVDVNLNG 389 + D TD Q + A T F +DI+INNAG M + W +++NL G Sbjct: 61 IVA--DFTDEHQAQRAVRETEAAFGWLDILINNAGVMYLEPVATADLGRWRSMLELNLLG 118 Query: 390 VIRGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYH 569 +I T A M + G IVN ASTA + Y+A+ + ++G + + + H Sbjct: 119 LIAATQAALPGMTARKDGH---IVNIASTAGHIANPLSAAYSASKFGVIGFSESLRKEVH 175 Query: 570 VNVTGVRCLVVCPGLTDSGL 629 + +R V+ PG+ + L Sbjct: 176 KD--NIRVTVISPGMAATEL 193 >UniRef50_A4M6M0 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Petrotoga mobilis SJ95 Length = 248 Score = 90.2 bits (214), Expect = 5e-17 Identities = 57/217 (26%), Positives = 99/217 (45%), Gaps = 8/217 (3%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLF 239 M L K+A++TG + GIG S +K+GA V ID ER Q+ E S + ++ Sbjct: 1 MKLNQKIAIVTGGSRGIGKEISRNFIKEGATVIAIAID-ER-PQIEENEKSDFPEDRFIY 58 Query: 240 CRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRL--------WELEVDVNLNGVI 395 + D+TD+ E ++ +IDI++NNAG D ++ + VNL G Sbjct: 59 YQADITDFNAISEIVTEIYNKYQKIDILVNNAGMAKDNFLVIMKEEDFDKVIQVNLKGTF 118 Query: 396 RGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVN 575 T + M K + G I++ AS + Y+A I+G+T+++ + + Sbjct: 119 VMTKAVAKIMRKQKFGN---IISMASVVGIEGNIGQTNYSAAKAGIIGMTKSWAKELTMK 175 Query: 576 VTGVRCLVVCPGLTDSGLVXDLDKQLMSSKYETAWLE 686 +R + PG +G+ L ++L+ E L+ Sbjct: 176 GENIRVNAIAPGFVRTGMTESLKEELIEYVVENTCLK 212 >UniRef50_A1UKM6 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=6; Mycobacterium|Rep: Short-chain dehydrogenase/reductase SDR precursor - Mycobacterium sp. (strain KMS) Length = 274 Score = 90.2 bits (214), Expect = 5e-17 Identities = 66/199 (33%), Positives = 94/199 (47%), Gaps = 8/199 (4%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLF 239 MD G+ A++TGA SGIG A L+ GA+V DID++ E L +++ Sbjct: 1 MDFAGRQAIVTGAGSGIGAALCRALVAAGAEVLCTDIDADAAEATARGLGARWS------ 54 Query: 240 CRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAG--------FMNDRLWELEVDVNLNGVI 395 LDVTD + A V R+D++ NNAG + W +D+N+ GV+ Sbjct: 55 -PLDVTDAAAVQRAVDEVVARAGRLDLMFNNAGISWGGDTELLTLDQWNAIIDINIRGVV 113 Query: 396 RGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVN 575 G AY M R G G IVNTAS A Y T +A+VGL+ A + + Sbjct: 114 HGVAAAYPQM--IRQGHGH-IVNTASMAGLTAAGLITSYVMTKHAVVGLSLALRSEAVAH 170 Query: 576 VTGVRCLVVCPGLTDSGLV 632 GV L VCP ++ ++ Sbjct: 171 --GVGVLAVCPAAVETPIL 187 >UniRef50_P16544 Cluster: Putative ketoacyl reductase; n=42; Bacteria|Rep: Putative ketoacyl reductase - Streptomyces coelicolor Length = 261 Score = 90.2 bits (214), Expect = 5e-17 Identities = 66/192 (34%), Positives = 94/192 (48%), Gaps = 9/192 (4%) Frame = +3 Query: 75 KVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYG-RKNVLFCRLD 251 +VAL+TGA SGIGL + L K+G +V +C E G + T K + G + C D Sbjct: 7 EVALVTGATSGIGLEIARRLGKEGLRVFVC-ARGEEGLRTTLKELREAGVEADGRTC--D 63 Query: 252 VTDYPQFEEAFVMTVEEFNRIDIVINNAG--------FMNDRLWELEVDVNLNGVIRGTL 407 V P+ E VE + +D+++NNAG + D LW V+ NL GV R T Sbjct: 64 VRSVPEIEALVAAVVERYGPVDVLVNNAGRPGGGATAELADELWLDVVETNLTGVFRVTK 123 Query: 408 LAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTGV 587 + G G G IVN AST + V Y+A+ + +VG T+A G + TG+ Sbjct: 124 QVLKAGGMLERGTGR-IVNIASTGGKQGVVHAAPYSASKHGVVGFTKALG--LELARTGI 180 Query: 588 RCLVVCPGLTDS 623 VCPG ++ Sbjct: 181 TVNAVCPGFVET 192 >UniRef50_Q5LDH2 Cluster: Putative 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase; n=2; Bacteroidales|Rep: Putative 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase - Bacteroides fragilis (strain ATCC 25285 / NCTC 9343) Length = 250 Score = 89.8 bits (213), Expect = 6e-17 Identities = 71/198 (35%), Positives = 101/198 (51%), Gaps = 9/198 (4%) Frame = +3 Query: 75 KVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCRLDV 254 KVA++TGA++GIGLA +E K GA V L DI +E EQ KL S+ G K V + R DV Sbjct: 7 KVAMVTGASAGIGLASAEAFAKAGATVVLVDI-NEPKEQ-AGKLVSE-GYKAVAY-RCDV 62 Query: 255 TDYPQFEEAFVMTVEEFNRIDIVINNAGF---------MNDRLWELEVDVNLNGVIRGTL 407 +D +E TV + R+D +NNAG + D ++ V V+L GV Sbjct: 63 SDTRAVKEMIDWTVATYGRLDAALNNAGIQTPQRPMAEITDEEFDRTVAVDLKGV--WNC 120 Query: 408 LAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTGV 587 + Y + + G GG IVNT+S Y A +A++GLTR Y + G+ Sbjct: 121 MRYEIIQMLQQG-GGAIVNTSSQGGVTGFPGQAAYIACKHAVIGLTRTAAIDY--SAKGI 177 Query: 588 RCLVVCPGLTDSGLVXDL 641 R VCPG+ + + +L Sbjct: 178 RINAVCPGVIRTPMAEEL 195 >UniRef50_Q12DF3 Cluster: Short-chain dehydrogenase/reductase SDR; n=38; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Polaromonas sp. (strain JS666 / ATCC BAA-500) Length = 250 Score = 89.8 bits (213), Expect = 6e-17 Identities = 67/203 (33%), Positives = 103/203 (50%), Gaps = 6/203 (2%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLF 239 +DL +VA+ITG A G+G A ++ +L GA V+L DID++R Q E L G+ V+ Sbjct: 4 LDLNQRVAVITGGAQGMGYATAQRMLASGAAVALWDIDAQRLAQARETLKPS-GK--VIT 60 Query: 240 CRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFM--NDRLWELEVDVNLNGV---IRGT 404 +++TD E A T+ F RIDI++NNAG N WEL +V + + G Sbjct: 61 AVVELTDEASVEAATQATLAAFGRIDILVNNAGITGGNGTTWELAPEVWRRVIEVNLIGP 120 Query: 405 LLAYRFMGKDRGGQG-GVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVT 581 L R + QG G IVN AS A + Y+A+ ++GLT++ G + + T Sbjct: 121 YLTSRAIVPHMVKQGYGRIVNIASVAGKEGNPNASHYSASKAGLIGLTKSLGKE--LAKT 178 Query: 582 GVRCLVVCPGLTDSGLVXDLDKQ 650 GV V P + + + ++ Sbjct: 179 GVLVNAVTPAAAKTAIFDSMKQE 201 >UniRef50_Q0RTV0 Cluster: Short-chain dehydrogenase, SDR family; n=1; Frankia alni ACN14a|Rep: Short-chain dehydrogenase, SDR family - Frankia alni (strain ACN14a) Length = 276 Score = 89.8 bits (213), Expect = 6e-17 Identities = 58/192 (30%), Positives = 95/192 (49%), Gaps = 7/192 (3%) Frame = +3 Query: 63 DLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFC 242 +L GK A++TG +SGIGLA +E + +GA V + DI ERG E+L L+ Sbjct: 4 NLVGKTAIVTGGSSGIGLASAEAFVAEGAHVVIGDIQDERGRAAAERLGDA-----ALYV 58 Query: 243 RLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRLWELE-----VDVNLNGVIRGTL 407 DV+D Q V F +DI+ NNA D+ ++ +D +L ++ + Sbjct: 59 HTDVSDDDQVANLVDTAVRHFGGLDIMFNNASGAGDQAGLVDLGPDGLDRSLRLIVGSAV 118 Query: 408 LAYRFMGK--DRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVT 581 +R + G+GG I+ T+S + R + P YT +A++G+ R + + Sbjct: 119 SGHRHAARVFIEQGRGGSIITTSSGSGLRGGLGQPSYTIGKHAVIGVVRHAAAE--LGRH 176 Query: 582 GVRCLVVCPGLT 617 G+R +CPG+T Sbjct: 177 GIRSNAICPGIT 188 >UniRef50_A0Z7K1 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; unclassified Gammaproteobacteria (miscellaneous)|Rep: Short-chain dehydrogenase/reductase SDR - marine gamma proteobacterium HTCC2080 Length = 297 Score = 89.8 bits (213), Expect = 6e-17 Identities = 65/194 (33%), Positives = 97/194 (50%), Gaps = 9/194 (4%) Frame = +3 Query: 69 KGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCRL 248 +GK A+I+G A GIGL+ ++ L +Q V L DID + E+ +L S VL L Sbjct: 11 QGKTAIISGGAEGIGLSIAKALGEQQMNVVLADIDKDNLERARLELQSL--GVPVLAVSL 68 Query: 249 DVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMND---------RLWELEVDVNLNGVIRG 401 DV D Q++ A VE F +I +V+NNAG D W+ +DVNL GV+ G Sbjct: 69 DVADEGQWQLAAEAAVERFGKIHMVVNNAGVGGDSGPIESQEKEGWQWALDVNLMGVVYG 128 Query: 402 TLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVT 581 + + + G+GG I+N AS A + Y AT A+V L+ A+ ++ + Sbjct: 129 AKVVVPLIKEH--GEGGWIINVASMAGMGGVPYSGAYNATKAAVVALSEAWSEE--LKSK 184 Query: 582 GVRCLVVCPGLTDS 623 V V+CP + Sbjct: 185 SVHVAVLCPAFVQT 198 >UniRef50_A0M1K4 Cluster: Short-chain dehydrogenase/reductase family protein; n=4; cellular organisms|Rep: Short-chain dehydrogenase/reductase family protein - Gramella forsetii (strain KT0803) Length = 249 Score = 89.8 bits (213), Expect = 6e-17 Identities = 70/228 (30%), Positives = 112/228 (49%), Gaps = 14/228 (6%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLF 239 M +KGK +ITGA+SGIG A + L K+G V L E+ +++ K+ + G K L Sbjct: 1 MSMKGKTIIITGASSGIGEATAMRLAKEGVNVVLTARREEKLKELKSKIDKENGGK-ALV 59 Query: 240 CRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFM--------NDRLWELEVDVNLNGVI 395 DVT F+ T +EF ID +INNAG M + W+ VDVN+ GV+ Sbjct: 60 IPGDVTKKEDFKNLIDKTKKEFGSIDGLINNAGLMPLSYVKNLHTDEWDKMVDVNIKGVL 119 Query: 396 RGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAI----VGLTRAYGDQ 563 G M + + G I+N +S+A + +Y AT A+ GL + + Sbjct: 120 NGVAAVLPTMMEQKSGN---IINISSSAARKIYPGGAVYCATKSAVKMFSEGLRQELAPK 176 Query: 564 YHVNVTGVRCLVVCPGLTDSGLVXDLDKQLMSSKYETAWL--EDITDS 701 +++N+T + V LTD+ ++ + ++S+ E L EDI ++ Sbjct: 177 FNINITSIEPGFVDTELTDTITDDEIKEDVLSNFKEMTPLQAEDIANA 224 >UniRef50_A7HRW0 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Parvibaculum lavamentivorans DS-1|Rep: Short-chain dehydrogenase/reductase SDR - Parvibaculum lavamentivorans DS-1 Length = 273 Score = 89.4 bits (212), Expect = 8e-17 Identities = 65/202 (32%), Positives = 101/202 (50%), Gaps = 12/202 (5%) Frame = +3 Query: 63 DLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFC 242 D+ + A ITG A+GIGL + L + GA+++L D+D+ + +L + +V Sbjct: 3 DIADRTAFITGGANGIGLGIARSLAQAGARLALVDLDAAALARAEMELCA---ITDVFTA 59 Query: 243 RLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF--------MNDRLWELEVDVNLNGVIR 398 LDV D + + + I+INNAG + LW+ + +NL GVI Sbjct: 60 VLDVRDRDGYARVADEAEAKLGPVSILINNAGVSGGTRASRLTYELWDWGIGINLGGVIN 119 Query: 399 GTLLAYRFMGK--DRGGQGGVIVNTASTAFARPQV--STPIYTATNYAIVGLTRAYGDQY 566 G F+ + +RGG GG IVNTAS A P V + +YT YA+VG++ A G Sbjct: 120 G---VQTFLPRIIERGG-GGHIVNTASGAGLVPPVREGSTLYTTAKYAVVGMSEALG--L 173 Query: 567 HVNVTGVRCLVVCPGLTDSGLV 632 + G+ V+CPG +G++ Sbjct: 174 ELESQGIGVTVLCPGPVATGII 195 >UniRef50_A1SJV4 Cluster: Short-chain dehydrogenase/reductase SDR; n=9; cellular organisms|Rep: Short-chain dehydrogenase/reductase SDR - Nocardioides sp. (strain BAA-499 / JS614) Length = 259 Score = 89.4 bits (212), Expect = 8e-17 Identities = 66/203 (32%), Positives = 104/203 (51%), Gaps = 11/203 (5%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 ++G+VA+ITG SGIGLA + +++GAKV + DID RG Q+ E+L G + Sbjct: 5 IQGRVAVITGGCSGIGLATVQRFVQEGAKVVIGDIDDARGHQLVEQLG---GADVATYVH 61 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFM---NDRLWELEVD-------VNLNGVI 395 +DVT Q + F + + +DI NNAG +D + + ++D VNL V Sbjct: 62 VDVTSKEQVDALFQTAKDAYGSVDIAFNNAGISPPEDDSILDTDLDAWRKVQEVNLTSVY 121 Query: 396 RGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPI-YTATNYAIVGLTRAYGDQYHV 572 A M + G+G I+NTAS ++ I Y+A+ ++ +TR G Q+ Sbjct: 122 LCCKAALPHMLEQ--GRGS-IINTASFVAVMGAATSQISYSASKGGVLSMTRELGVQFAR 178 Query: 573 NVTGVRCLVVCPGLTDSGLVXDL 641 GVR +CPG ++ L+ +L Sbjct: 179 Q--GVRVNALCPGPVNTPLLQEL 199 >UniRef50_Q4J9F2 Cluster: Short chain dehydrogenase; n=1; Sulfolobus acidocaldarius|Rep: Short chain dehydrogenase - Sulfolobus acidocaldarius Length = 255 Score = 89.4 bits (212), Expect = 8e-17 Identities = 65/197 (32%), Positives = 96/197 (48%), Gaps = 9/197 (4%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 LK KV ++TGA SGIG A +++ + V ++ +R Q+ ++L K VL + Sbjct: 6 LKNKVVIVTGAGSGIGRAIAKKFALNDSIVVAVELLEDRLNQIVQELRGM--GKEVLGVK 63 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFM---------NDRLWELEVDVNLNGVIR 398 DV+ EE T E ++RID++ NNAG M +D LWE + VNL Sbjct: 64 ADVSKKKDVEEFVRRTFETYSRIDVLCNNAGIMDGVTPVAEVSDELWERVLAVNLYSAFY 123 Query: 399 GTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNV 578 + M K G+ GVIVNTAS A R + YT + ++GLTR+ H Sbjct: 124 SSRAVIPIMLKQ--GK-GVIVNTASIAGIRGGFAGAPYTVAKHGLIGLTRSIA--AHYGD 178 Query: 579 TGVRCLVVCPGLTDSGL 629 G+R + V PG + + Sbjct: 179 QGIRAVAVLPGTVKTNI 195 >UniRef50_P07914 Cluster: Bile acid 7-dehydroxylase 1/3; n=3; Clostridium|Rep: Bile acid 7-dehydroxylase 1/3 - Eubacterium sp. (strain VPI 12708) Length = 249 Score = 89.4 bits (212), Expect = 8e-17 Identities = 63/211 (29%), Positives = 105/211 (49%), Gaps = 8/211 (3%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 ++ K+ +ITG GIG A ++ ++ GAKVS+ E + +L Y + VL Sbjct: 4 VQDKITIITGGTRGIGFAAAKLFIENGAKVSIFGETQEEVDTALAQLKELYPEEEVLGFA 63 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF-MN---DRLWELE----VDVNLNGVIRG 401 D+T A +++ R+D++INNAG MN R+ E + +D+N+NGV G Sbjct: 64 PDLTSRDAVMAAVGTVAQKYGRLDVMINNAGITMNSVFSRVSEEDFKNIMDINVNGVFNG 123 Query: 402 TLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVT 581 AY+ M KD + GVI+NTAS +S Y + ++GLT G + + Sbjct: 124 AWSAYQCM-KD--AKQGVIINTASVTGIYGSLSGIGYPTSKAGVIGLTHGLGRE--IIRK 178 Query: 582 GVRCLVVCPGLTDSGLVXDLDKQLMSSKYET 674 +R + V PG+ D+ + L +++ +T Sbjct: 179 NIRVVGVAPGVVDTDMTKGLPPEILEDYLKT 209 >UniRef50_Q13E96 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Rhodopseudomonas palustris BisB5|Rep: Short-chain dehydrogenase/reductase SDR - Rhodopseudomonas palustris (strain BisB5) Length = 263 Score = 89.0 bits (211), Expect = 1e-16 Identities = 63/206 (30%), Positives = 95/206 (46%), Gaps = 9/206 (4%) Frame = +3 Query: 75 KVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCRLDV 254 +V L+TG ASGIG A + +QG V + DID G + E + + G + + R DV Sbjct: 21 RVVLVTGGASGIGRAAALAWARQGCSVLVADIDDRGGAETVEAI-ERLGSR-ARYQRNDV 78 Query: 255 TDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRL---------WELEVDVNLNGVIRGTL 407 TD + V F R+D+ NNAG W ++VNL G+ Sbjct: 79 TDERECASLVEQAVLHFGRLDVAFNNAGITGPSAYIANYPGADWRHVINVNLLGIFNSMQ 138 Query: 408 LAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTGV 587 R + +G GVIVNTAS R Y A + ++GLT+ +Y +G+ Sbjct: 139 PQLRLF-ESQG--AGVIVNTASVIGLRGVAGGSAYAAAKHGVIGLTKCAALEY--GRSGI 193 Query: 588 RCLVVCPGLTDSGLVXDLDKQLMSSK 665 R VCPG ++ LV + ++++ K Sbjct: 194 RINAVCPGYIETPLVAAVPDRILTEK 219 >UniRef50_Q1NAA1 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Sphingomonas sp. SKA58|Rep: Short-chain dehydrogenase/reductase SDR - Sphingomonas sp. SKA58 Length = 248 Score = 89.0 bits (211), Expect = 1e-16 Identities = 68/196 (34%), Positives = 96/196 (48%), Gaps = 5/196 (2%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 ++GKV L+TGAA G+G A +E L ++GA+V + D+D E ++V + L + + R Sbjct: 7 VEGKVVLVTGAAHGLGRADAEALAREGARVIVADVDEEEAQRVADGLPA------AIALR 60 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAG---FMNDRLWELEVDVNLNGV-IRGTLLA 413 LDVT Q++ A + R+D ++NNAG F LEV + V GT L Sbjct: 61 LDVTSEAQWQAALTKIMWAHGRLDALVNNAGIAAFETVEQSSLEVFRRVMAVSAEGTFLG 120 Query: 414 YRFMGKDRGGQG-GVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTGVR 590 R G G IVN AS A R S Y+A AI+ +TR+ VR Sbjct: 121 CRTCLPALAASGAGSIVNIASVAAIRGNPSVFAYSAAKGAILSMTRSLIVHCQQQGYPVR 180 Query: 591 CLVVCPGLTDSGLVXD 638 VV PG D+ +V D Sbjct: 181 ANVVLPGSHDTQMVRD 196 >UniRef50_A1SJM6 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Nocardioides sp. (strain BAA-499 / JS614) Length = 253 Score = 89.0 bits (211), Expect = 1e-16 Identities = 64/194 (32%), Positives = 92/194 (47%), Gaps = 6/194 (3%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLF 239 +D GKV LITG A+GIG A + +QGA+V + D+D E T +L + G LF Sbjct: 5 LDFTGKVVLITGGATGIGRATALAFAQQGARVVVGDVDDRAAE--TVRLIEESG-GTALF 61 Query: 240 CRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMND-----RLWELEVDVNLNGVIRGT 404 R DVT ++ TV+ + + + NNAG + E + D + ++G Sbjct: 62 VRTDVTSAADVQQLVRTTVDTYGGLHVAFNNAGILPPTGPLAEQSEDDFDRTIAVDLKGV 121 Query: 405 LLAYRF-MGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVT 581 LA ++ + GG I+NTAS A Y A + +VGLTRA Y Sbjct: 122 FLALKYEIEHMAAAGGGSIINTASVAGVIADPGMAPYVAAKHGVVGLTRAAAIDY--AAA 179 Query: 582 GVRCLVVCPGLTDS 623 GVR + PGL D+ Sbjct: 180 GVRVNALAPGLVDT 193 >UniRef50_Q7SI45 Cluster: Putative uncharacterized protein NCU00606.1; n=2; Sordariales|Rep: Putative uncharacterized protein NCU00606.1 - Neurospora crassa Length = 262 Score = 89.0 bits (211), Expect = 1e-16 Identities = 61/210 (29%), Positives = 97/210 (46%), Gaps = 9/210 (4%) Frame = +3 Query: 69 KGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCRL 248 +GK L TGAA G+G +E L GA V +CD++ +R V E+ Y + L + Sbjct: 5 QGKTVLATGAAGGLGKVIAETFLAAGANVIICDVNQQRNSAVEEEWTRTYADR-FLIKQT 63 Query: 249 DVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMND---------RLWELEVDVNLNGVIRG 401 DV++ +E +V +F R+D+++NNA M+D LW+ + +NL G Sbjct: 64 DVSNEAAVQELIDASVAKFGRLDVLVNNAAIMDDFSPAGDCSKELWDRVMAINLTGPFLT 123 Query: 402 TLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVT 581 T A + K + GG+I+N S A S YT + I+ LT+ Y Sbjct: 124 TKAAVKQFEKQKQA-GGIIINIGSNASYMGFQSGAAYTVSKAGIMALTKNTAGFYADKGI 182 Query: 582 GVRCLVVCPGLTDSGLVXDLDKQLMSSKYE 671 L++ GLT + +V K + Y+ Sbjct: 183 YTMALLL-GGLTGTNIVDSFAKGMHMEMYQ 211 >UniRef50_P39640 Cluster: Bacilysin biosynthesis oxidoreductase bacC; n=5; Bacillus|Rep: Bacilysin biosynthesis oxidoreductase bacC - Bacillus subtilis Length = 253 Score = 89.0 bits (211), Expect = 1e-16 Identities = 75/235 (31%), Positives = 107/235 (45%), Gaps = 10/235 (4%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLF 239 M+L K LITG ASGIG A + L Q A V + DID +G E + K + F Sbjct: 1 MNLTDKTVLITGGASGIGYAAVQAFLGQQANVVVADIDEAQG----EAMVRKENNDRLHF 56 Query: 240 CRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF--------MNDRLWELEVDVNLNGVI 395 + D+TD + A V F +D++INNAG M W + VNL G+ Sbjct: 57 VQTDITDEAACQHAVESAVHTFGGLDVLINNAGIEIVAPIHEMELSDWNKVLQVNLTGMF 116 Query: 396 RGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVN 575 + A + M G+G I+NT S P Y A+ ++ LT++ Y + Sbjct: 117 LMSKHALKHM--LAAGKGN-IINTCSVGGLVAWPDIPAYNASKGGVLQLTKSMAVDYAKH 173 Query: 576 VTGVRCLVVCPGLTDSGLVXDLDKQLMSSKYETAWLEDITDSKCRA--LITLGKP 734 V C VCPG+ D+ L +K + + T LE+I K + L+ LGKP Sbjct: 174 QIRVNC--VCPGIIDTPL---NEKSFLENNEGT--LEEIKKEKAKVNPLLRLGKP 221 >UniRef50_A7HWN9 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Parvibaculum lavamentivorans DS-1|Rep: Short-chain dehydrogenase/reductase SDR precursor - Parvibaculum lavamentivorans DS-1 Length = 294 Score = 88.6 bits (210), Expect = 1e-16 Identities = 68/193 (35%), Positives = 92/193 (47%), Gaps = 10/193 (5%) Frame = +3 Query: 63 DLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDI-DSERGEQVTEKLASKYGRKNVLF 239 DL+GK A +TG ASGIGL+ + G V L DI + + G V E + V Sbjct: 4 DLQGKTAFVTGGASGIGLSMARAFGAAGMNVMLADINEDDLGVAVAELNERQIKAAGV-- 61 Query: 240 CRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF--------MNDRLWELEVDVNLNGVI 395 R DV D E+A TV + ++ +V NNAG + W+ + VNL GV+ Sbjct: 62 -RCDVADRKSLEQAAEETVATYGKVHVVCNNAGVGAGGAIGTVKPGDWDWTIAVNLMGVV 120 Query: 396 RGTLLAYRFMGKDRG-GQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHV 572 GT F+ R G+GG VNTAS A YTA+ YA+VG++ + Q Sbjct: 121 YGT---EAFLPHIRAHGEGGHFVNTASMAGMISVPGMEPYTASKYAVVGMSEGWAGQLAP 177 Query: 573 NVTGVRCLVVCPG 611 GV V+CPG Sbjct: 178 ENIGVS--VLCPG 188 >UniRef50_A6CM25 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family protein; n=6; Bacteria|Rep: Oxidoreductase, short chain dehydrogenase/reductase family protein - Bacillus sp. SG-1 Length = 245 Score = 88.6 bits (210), Expect = 1e-16 Identities = 58/182 (31%), Positives = 94/182 (51%), Gaps = 8/182 (4%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 ++ KVA++TG A+GIG A +E K+ V L D E G ++T +L ++ G V+F + Sbjct: 1 MESKVAIVTGGANGIGKAIVKEFCKENYTVILVDKKEEEGLELTREL-NESG-NTVIFKK 58 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMN-DRLWELEVDVNLNGVIRGTLLAYRF 422 DV +Y + + F E F ++DI+INNAG W++E + + N VI L + + Sbjct: 59 CDVGNYAEVKHLFNEIKETFQKVDILINNAGISKFKNFWDME-EKDWNEVISTNLSSVFY 117 Query: 423 MGKDRG----GQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYG---DQYHVNVT 581 K+ GG I+N AST + +T Y+A+ I LT A +Y++ V Sbjct: 118 FSKEAALLMKDMGGCIINMASTRATMSEANTEAYSASKGGIFSLTHALAMTLSEYNIRVN 177 Query: 582 GV 587 + Sbjct: 178 SI 179 >UniRef50_Q4A054 Cluster: Uncharacterized oxidoreductase SSP0419; n=15; Staphylococcus|Rep: Uncharacterized oxidoreductase SSP0419 - Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 /DSM 20229) Length = 234 Score = 88.6 bits (210), Expect = 1e-16 Identities = 66/204 (32%), Positives = 104/204 (50%), Gaps = 9/204 (4%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLF 239 ++L+ KVA++TGA+SGIG + +E L QG KV L D R +V +++ + V Sbjct: 2 VELQDKVAVVTGASSGIGASIAETLANQGVKVVLTGRDESRLAEVAKRIQDN-KQAVVET 60 Query: 240 CRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFM--------NDRLWELEVDVNLNGVI 395 +DVT + E T E+F +IDI++N+AG M + WE +DVN I Sbjct: 61 SIVDVTHKEEVTELVEKTKEKFGQIDILVNSAGLMLSSAITEGDVEAWEAMIDVN----I 116 Query: 396 RGTLLAYRFMGKDRGGQ-GGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHV 572 +GTL + Q G I+N AS + + +Y+A+ A+ +T+ G + + Sbjct: 117 KGTLYTINAVLPSMLNQSSGHIINIASISGFEVTKKSTLYSASKAAVHSITQ--GLEKEL 174 Query: 573 NVTGVRCLVVCPGLTDSGLVXDLD 644 TGVR + PG+ D+ L D D Sbjct: 175 AKTGVRVTSISPGMVDTPLSGDTD 198 >UniRef50_Q88T73 Cluster: Short-chain dehydrogenase/oxidoreductase; n=7; Bacilli|Rep: Short-chain dehydrogenase/oxidoreductase - Lactobacillus plantarum Length = 248 Score = 88.2 bits (209), Expect = 2e-16 Identities = 66/199 (33%), Positives = 100/199 (50%), Gaps = 8/199 (4%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLF 239 M +KGKV +ITGA+SGIG A ++ L +GAKV L R E+ + L+ G N ++ Sbjct: 1 MSIKGKVVVITGASSGIGAATAKLLAAKGAKVVL----GARREERLQALSQAIG-DNAVY 55 Query: 240 CRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFM-----NDR---LWELEVDVNLNGVI 395 DVTD Q + V +F R+D++ NNAG M +DR W++ ++VN+ GV+ Sbjct: 56 QVTDVTDRQQVRALIDLAVSKFGRVDVLYNNAGTMPQGNLSDREYDKWQMMLNVNIMGVL 115 Query: 396 RGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVN 575 G M K G+I+ T S A ++ +Y T YA+ + G + Sbjct: 116 NGIGEVLPIMQKQ---HDGLIIATDSVAGHVVYPASAVYNGTKYAVRAIME--GLRQEEK 170 Query: 576 VTGVRCLVVCPGLTDSGLV 632 G+R +V PG + LV Sbjct: 171 EHGIRSTIVSPGAVRTELV 189 >UniRef50_Q5WBV7 Cluster: 3-oxoacyl-[acyl-carrier-protein] reductase; n=1; Bacillus clausii KSM-K16|Rep: 3-oxoacyl-[acyl-carrier-protein] reductase - Bacillus clausii (strain KSM-K16) Length = 255 Score = 88.2 bits (209), Expect = 2e-16 Identities = 69/202 (34%), Positives = 99/202 (49%), Gaps = 20/202 (9%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 + GKV+++TGAA GIG A + EL K+GA V L D+ S EQ E +A+ G V+ Sbjct: 4 MAGKVSIVTGAARGIGAAAAIELAKEGADVVLVDVLS--CEQTKETIATDVGGAEVVCYE 61 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAG--------FMNDRLWELEVDVNLNGVIRG 401 +DV + + E F RID+V+NNAG M D +W ++D NL G Sbjct: 62 VDVKNRDEVEGLMKAVNRRFGRIDVVVNNAGTCCRYDLESMTDEMWHRDIDTNLRGTFLM 121 Query: 402 TLLA-YRFMGKDRGGQGGVIVNTASTA------FA-----RPQVSTPIYTATNYAIVGLT 545 T A Y +M K +G G I+N +S + FA R + S P Y A+ ++ T Sbjct: 122 TQTAIYPYM-KQQG--NGKIINISSISGIMGGPFAFNEGERAERSGPAYAASKGGVIAFT 178 Query: 546 RAYGDQYHVNVTGVRCLVVCPG 611 R + V G+ C + PG Sbjct: 179 RWVAKE--VGRLGITCNSIAPG 198 >UniRef50_Q47PW1 Cluster: Short-chain dehydrogenase/reductase (SDR) family protein; n=1; Thermobifida fusca YX|Rep: Short-chain dehydrogenase/reductase (SDR) family protein - Thermobifida fusca (strain YX) Length = 282 Score = 88.2 bits (209), Expect = 2e-16 Identities = 64/191 (33%), Positives = 98/191 (51%), Gaps = 9/191 (4%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 L+G+VA ITG ASGIG A +GA V + DI +E G ++ ++L + +F R Sbjct: 5 LRGRVAAITGGASGIGEATVRRFHTEGASVVIADIQAEAGRRLADELGDR-----AVFVR 59 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMN-------DRL--WELEVDVNLNGVIR 398 DV++ V+ F ++DI++NNAG M R+ +L + VNL GVI Sbjct: 60 TDVSEEADVAALVDTAVDRFGQLDIMVNNAGIMGALGPIDATRMSDADLTIAVNLRGVIC 119 Query: 399 GTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNV 578 G A R M K R + GVI++T+S A + IY+A I+GL+ + + + Sbjct: 120 GMKHAARVM-KPR--RSGVIISTSSPAGVLGGIGPHIYSAVKVGIIGLSNSVAAELRQH- 175 Query: 579 TGVRCLVVCPG 611 G+R + PG Sbjct: 176 -GIRVNTIIPG 185 >UniRef50_Q11G59 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=9; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR precursor - Mesorhizobium sp. (strain BNC1) Length = 251 Score = 88.2 bits (209), Expect = 2e-16 Identities = 65/208 (31%), Positives = 98/208 (47%), Gaps = 10/208 (4%) Frame = +3 Query: 63 DLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFC 242 + K KVAL+TGA SGIG A + EL GA++ + D++ E ++ E + + GR + Sbjct: 4 EFKDKVALVTGAGSGIGAAIARELATGGAELVVADLERESANRIVEGIRASGGRAHAF-- 61 Query: 243 RLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRL---------WELEVDVNLNGVI 395 +DV D E V + + +NNAG W +DVNLNGV Sbjct: 62 AVDVADAEAVERMVDFAVRTCGDLHLAVNNAGIGGPSEPTADYPLDGWRKVIDVNLNGVF 121 Query: 396 RGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVN 575 G + Y + G GG IVN AS + + Y + +A++GLT+ +Y Sbjct: 122 YG--MKYEIAAILKSG-GGAIVNMASILGSVGFANACAYVSAKHALLGLTKTAAMEYAAQ 178 Query: 576 VTGVRCLVVCPGLTDSGLV-XDLDKQLM 656 GVR V P D+ L+ +LD Q++ Sbjct: 179 --GVRINAVGPAFIDTPLLSKNLDDQVL 204 >UniRef50_Q11E37 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Mesorhizobium sp. BNC1|Rep: Short-chain dehydrogenase/reductase SDR - Mesorhizobium sp. (strain BNC1) Length = 260 Score = 88.2 bits (209), Expect = 2e-16 Identities = 63/196 (32%), Positives = 97/196 (49%), Gaps = 8/196 (4%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLF 239 M L K+A ITGAA GIG + ++GAKV L DID +RG +V +++ S G + +F Sbjct: 1 MRLANKIAFITGAAEGIGACAAGLFSREGAKVILSDIDEDRGRKVADQVTSAGG--DAVF 58 Query: 240 CRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF---MNDRLWELEVD-----VNLNGVI 395 R DVT EA E + + I+ NN G +DR+ +++++ + LN V+ Sbjct: 59 VRCDVTSEASVREAAAAVQERYGALHILYNNVGGSTPRDDRVTDVDLEEFWSAMKLN-VL 117 Query: 396 RGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVN 575 L A + GG ++NTAS YTA+ A+V LTR+ ++ Sbjct: 118 SVVLPARHLIPLIAASGGGSVINTASYMALLGTAGRDCYTASKGAVVSLTRSMAVEF--G 175 Query: 576 VTGVRCLVVCPGLTDS 623 +R V+ PG D+ Sbjct: 176 PDNIRVNVIGPGAVDT 191 >UniRef50_A3BN50 Cluster: Putative uncharacterized protein; n=2; Oryza sativa|Rep: Putative uncharacterized protein - Oryza sativa subsp. japonica (Rice) Length = 274 Score = 88.2 bits (209), Expect = 2e-16 Identities = 67/187 (35%), Positives = 92/187 (49%) Frame = +3 Query: 48 SSINMDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRK 227 +S + L GKVA+ITG ASGIG A +EE ++ GAKV L D+ + G V A++ G Sbjct: 25 ASDSQRLAGKVAVITGGASGIGRATAEEFVRNGAKVILADVQDDLGHAV----AAELGAD 80 Query: 228 NVLFCRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRLWELEVDVNLNGVIRGTL 407 + R DVTD Q A + V R+D+V NNAG V+ G Sbjct: 81 AASYARCDVTDEAQVAAAVDLAVARHGRLDVVFNNAGIP-------------RAVVAGVK 127 Query: 408 LAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTGV 587 A R M R G I+ TASTA V+ P Y+ + A++GL RA + + +GV Sbjct: 128 HAARVMVPRRRGS---IICTASTAGVIGGVAVPHYSVSKAAVLGLVRAVAGE--MARSGV 182 Query: 588 RCLVVCP 608 R + P Sbjct: 183 RVNAISP 189 >UniRef50_Q81WX9 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reductase, putative; n=10; Bacillus cereus group|Rep: 3-oxoacyl-(Acyl-carrier-protein) reductase, putative - Bacillus anthracis Length = 246 Score = 87.8 bits (208), Expect = 2e-16 Identities = 60/194 (30%), Positives = 97/194 (50%), Gaps = 8/194 (4%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 L GK A++TGAA GIG + K GAKV + D++ E+ ++ T +L + G + L+ R Sbjct: 4 LNGKTAVVTGAAQGIGKEIARVYAKLGAKVLISDVNEEKLQKTTRELLDE-GYEVSLY-R 61 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRL--------WELEVDVNLNGVIRG 401 DV++ + + V++F + I++NNAG D + WE + VNL GV Sbjct: 62 CDVSNQNEAKSLIEYAVQKFGTLHILVNNAGITRDAMLHKMEKSSWEQVLQVNLTGVFYC 121 Query: 402 TLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVT 581 A +M + G+ I+N +S + + Y AT +VGLT+ + V Sbjct: 122 MQPALLYMRQQGYGR---IINISSIS-REGNIGQANYAATKAGVVGLTKTAAKE--VGSF 175 Query: 582 GVRCLVVCPGLTDS 623 G+ C +CPG D+ Sbjct: 176 GITCNAICPGFMDT 189 >UniRef50_Q46PX5 Cluster: NAD-dependent epimerase/dehydratase:Short-chain dehydrogenase/reductase SDR; n=2; Bacteria|Rep: NAD-dependent epimerase/dehydratase:Short-chain dehydrogenase/reductase SDR - Ralstonia eutropha (strain JMP134) (Alcaligenes eutrophus) Length = 253 Score = 87.8 bits (208), Expect = 2e-16 Identities = 68/202 (33%), Positives = 94/202 (46%), Gaps = 9/202 (4%) Frame = +3 Query: 54 INMDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNV 233 I+M LK KVA++TG ASGIG A QGA V + D S GE++ +L+ + Sbjct: 4 IDMKLKDKVAIVTGGASGIGEATVRLFASQGASVVIAD-RSALGEKLARELSESSLAAH- 61 Query: 234 LFCRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF---------MNDRLWELEVDVNLN 386 + +DV+ TV F R+DI++ NAG ++ W+ +DVNL Sbjct: 62 -YSEVDVSREDDTRRLIDDTVSRFGRLDIMVANAGIAHPSAPVEDVSVEQWQQMIDVNLT 120 Query: 387 GVIRGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQY 566 GV LA M K G GG IVN AS Y A +V LTR+ G + Sbjct: 121 GVFLSNKLAIVQMKKQ--GTGGAIVNMASILGHVGMPGAASYNAAKGGVVNLTRSLGVSH 178 Query: 567 HVNVTGVRCLVVCPGLTDSGLV 632 + G+R VCPG + L+ Sbjct: 179 AQD--GIRVNAVCPGFVATPLI 198 >UniRef50_A4AQP3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reductase; n=1; Flavobacteriales bacterium HTCC2170|Rep: 3-oxoacyl-(Acyl-carrier protein) reductase - Flavobacteriales bacterium HTCC2170 Length = 245 Score = 87.8 bits (208), Expect = 2e-16 Identities = 60/205 (29%), Positives = 99/205 (48%), Gaps = 8/205 (3%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLF 239 M LK K+A++TG A GIG A SE K+GA V + D+ +G+ V E + + G+ + Sbjct: 1 MRLKDKIAVVTGGARGIGQAVSELFAKEGATVIIMDL-LPQGQAVAEGIIASGGKAE--Y 57 Query: 240 CRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRL--------WELEVDVNLNGVI 395 L VT+ E F +++ +IDI+INNAG DR W+ ++VNL GV Sbjct: 58 HSLSVTNKSDVEGVFSSVNDKYGKIDILINNAGITRDRTLEKMSEAEWDAVIEVNLKGVF 117 Query: 396 RGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVN 575 T +M + + G IV+ AS R Y AT ++ + + + ++ Sbjct: 118 ICTQAVVPYM---KASKYGRIVSAASNVGLRGNFGQTNYAATKAGVIAMAKTWTVEF--G 172 Query: 576 VTGVRCLVVCPGLTDSGLVXDLDKQ 650 G+ + PG T + +V + ++ Sbjct: 173 KYGITANAIAPGFTMTDMVKQIPEE 197 >UniRef50_A3XPR1 Cluster: Cyclohexanol dehydrogenase; n=1; Leeuwenhoekiella blandensis MED217|Rep: Cyclohexanol dehydrogenase - Leeuwenhoekiella blandensis MED217 Length = 261 Score = 87.8 bits (208), Expect = 2e-16 Identities = 67/226 (29%), Positives = 110/226 (48%), Gaps = 9/226 (3%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 +K +V +ITGAA G+GLA +E L K+GAK+ L D + + +KL +L + Sbjct: 1 MKDQVIIITGAAMGLGLATAELLAKEGAKLVLVDYNENALKDAEQKLKEINPEVALLSVK 60 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDR---------LWELEVDVNLNGVIR 398 DV+ Q + TVE+F RID + NNAG + +++ +D+NL GV Sbjct: 61 ADVSSEEQVKNYVDKTVEKFGRIDGLYNNAGIEGKQASIVDYDLDIFKKVIDINLMGVYY 120 Query: 399 GTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNV 578 G M K + G+ IVN AS R ++ Y A+ +A+ G+T+ +Y Sbjct: 121 GLRYVIPVMQKQKFGR---IVNVASVGGIRGVLNQMPYVASKHAVSGMTKNAALEY--GK 175 Query: 579 TGVRCLVVCPGLTDSGLVXDLDKQLMSSKYETAWLEDITDSKCRAL 716 G+ + PG + +V + KQ+ + A + +++ RAL Sbjct: 176 DGILTNAIAPGAILTPMVAEAFKQVNPEDPKAAEAQYASNNPTRAL 221 >UniRef50_A1ULZ8 Cluster: Short-chain dehydrogenase/reductase SDR; n=18; Corynebacterineae|Rep: Short-chain dehydrogenase/reductase SDR - Mycobacterium sp. (strain KMS) Length = 253 Score = 87.8 bits (208), Expect = 2e-16 Identities = 68/198 (34%), Positives = 101/198 (51%), Gaps = 11/198 (5%) Frame = +3 Query: 63 DLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFC 242 + K KVA++TGA GIG AY+E L ++GA V + DI+ + ++V + + + G N L Sbjct: 7 EFKDKVAIVTGAGGGIGQAYAEALAREGAAVVVADINVDGAQKVADGIKGEGG--NALAV 64 Query: 243 RLDVTDYPQFEEAFVMTVEEFNRIDIVINNA----GFMNDRL----WELE---VDVNLNG 389 R+DV+D +E T+ EF ID ++NNA G D L W+ + VNL+G Sbjct: 65 RVDVSDPDSAKEMAAQTLSEFGGIDYLVNNAAIFGGMKLDFLITVDWDYYKKFMSVNLDG 124 Query: 390 VIRGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYH 569 + T YR M K RG GG IVN +STA + + Y I GLT+ + Sbjct: 125 ALVCTRAVYRKMAK-RG--GGAIVNQSSTA---AWLYSNFYGLAKVGINGLTQQLATE-- 176 Query: 570 VNVTGVRCLVVCPGLTDS 623 + +R + PG D+ Sbjct: 177 LGGQNIRVNAIAPGPIDT 194 >UniRef50_Q0DM18 Cluster: Os03g0833100 protein; n=5; Oryza sativa|Rep: Os03g0833100 protein - Oryza sativa subsp. japonica (Rice) Length = 274 Score = 87.8 bits (208), Expect = 2e-16 Identities = 68/198 (34%), Positives = 97/198 (48%), Gaps = 7/198 (3%) Frame = +3 Query: 39 CFYSSINMDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKY 218 C S MD GKVA++TG ASGIG A + GA V + D+ E GE V +A Sbjct: 8 CIMSKTRMD--GKVAIVTGGASGIGEAAARLFASCGATVVIADVQDELGEAVAASVAGGG 65 Query: 219 GRKNVLFCRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRLWELEVDV-NLNGVI 395 R + R DVTD Q E A V E R+D++++NAG + +++D+ L+ V+ Sbjct: 66 CR----YVRCDVTDEAQVEAAVAAAVAEHGRLDVMVSNAGVLLPTGPVVDMDLAALDRVM 121 Query: 396 ----RGTLLAYRFMGKDRGGQG--GVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYG 557 RG + + +G G IV TAS A + YTA+ +A++GL RA Sbjct: 122 SVNFRGAAACVKHAARAMVSRGTRGAIVCTASVASCQGGFGPAAYTASKHAVLGLVRAAA 181 Query: 558 DQYHVNVTGVRCLVVCPG 611 + + GVR V PG Sbjct: 182 GE--LGRHGVRVNCVSPG 197 >UniRef50_A4QV37 Cluster: Putative uncharacterized protein; n=1; Magnaporthe grisea|Rep: Putative uncharacterized protein - Magnaporthe grisea (Rice blast fungus) (Pyricularia grisea) Length = 274 Score = 87.8 bits (208), Expect = 2e-16 Identities = 61/191 (31%), Positives = 94/191 (49%), Gaps = 10/191 (5%) Frame = +3 Query: 72 GKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCRLD 251 G+ L+TG A G+G A +E L+ GA V +CDI ER Q ++L + + +D Sbjct: 23 GRTCLVTGGAGGLGKAVAEAFLRAGANVVICDIHEERLAQTAKELGELGPLASFV---VD 79 Query: 252 VTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDR----------LWELEVDVNLNGVIRG 401 VT Q + F T F ++DI+INNAG + DR LW+ + VNL + Sbjct: 80 VTVEKQVRQLFDDTAARFGKVDILINNAG-LPDRFQPVGDVDMDLWDKVIAVNLTAPVLM 138 Query: 402 TLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVT 581 + A + M G GG I+N AS A +S Y A+ + ++G+T++ H Sbjct: 139 SKFAVKSMA--TGTTGGCIINMASVASKAGVLSGVAYVASKHGLLGITKS--TAVHYRDK 194 Query: 582 GVRCLVVCPGL 614 G+ C+ + GL Sbjct: 195 GIGCVALLIGL 205 >UniRef50_Q8F0K8 Cluster: 3-oxoacyl-(Acyl-carrier protein) reductase; n=4; Leptospira|Rep: 3-oxoacyl-(Acyl-carrier protein) reductase - Leptospira interrogans Length = 259 Score = 87.4 bits (207), Expect = 3e-16 Identities = 61/221 (27%), Positives = 109/221 (49%), Gaps = 11/221 (4%) Frame = +3 Query: 54 INMDLKGKVALITGAAS--GIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRK 227 ++ +GKVAL+TGAAS G+G A + + K+G + L D++ E+ EQ +A ++G K Sbjct: 5 MSKQFEGKVALVTGAASPRGLGRAIANTIAKEGGDIVLVDLNKEQIEQAAADVAKEFGVK 64 Query: 228 NV-LFCRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRL--------WELEVDVN 380 + L C +VT + E+F ++D ++NNAG + D L ++ +DVN Sbjct: 65 TLGLSC--NVTKPEDCDSVIAGVKEKFGKLDFLVNNAGVLKDNLFIRMSEQEFDFVLDVN 122 Query: 381 LNGVIRGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGD 560 L GV T A + + K + G IVN +S + Q Y+++ ++ LT+ Sbjct: 123 LKGVFLMTKYASKLLLK---AESGRIVNISSVSGLTGQPGQANYSSSKAGVIALTKVAAR 179 Query: 561 QYHVNVTGVRCLVVCPGLTDSGLVXDLDKQLMSSKYETAWL 683 ++ V VCPG + + L +++ + A++ Sbjct: 180 EFAGR--NVLVNAVCPGYVQTDMTASLPEEVQKKLTDPAFI 218 >UniRef50_Q5NM60 Cluster: Short-chain alcohol dehydrogenase; n=14; cellular organisms|Rep: Short-chain alcohol dehydrogenase - Zymomonas mobilis Length = 248 Score = 87.4 bits (207), Expect = 3e-16 Identities = 61/201 (30%), Positives = 100/201 (49%), Gaps = 8/201 (3%) Frame = +3 Query: 54 INMDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNV 233 +N +++ K+ +ITGA+SG+G + L GA V L ER + + +K G+ Sbjct: 1 MNQNIRNKIVVITGASSGLGAETARHLSDLGATVVLGARREERIATLANSIVAKGGQ--A 58 Query: 234 LFCRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMN----DRL----WELEVDVNLNG 389 L + DVTD + V+ + R+D+++NNAG M ++L WEL VDVN+ G Sbjct: 59 LAIKTDVTDRESVKNLVDTAVKTYGRVDVLLNNAGVMPLSPLEKLRVDEWELMVDVNIKG 118 Query: 390 VIRGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYH 569 V+ G A M + G I+N +S A + +Y+AT +A+ L+ G + Sbjct: 119 VLYGIAAALPHMKSQKFGH---IINVSSVAGHKVIDGGAVYSATKFAVRALSE--GLRAE 173 Query: 570 VNVTGVRCLVVCPGLTDSGLV 632 V +R ++ PG S L+ Sbjct: 174 VKSYNLRTTIISPGAVQSELI 194 >UniRef50_Q399N8 Cluster: Short-chain dehydrogenase/reductase SDR; n=27; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 / R18194)) Length = 595 Score = 87.4 bits (207), Expect = 3e-16 Identities = 66/195 (33%), Positives = 91/195 (46%), Gaps = 8/195 (4%) Frame = +3 Query: 72 GKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCRLD 251 GKVA++TGA SGIG + ++GA + CDID E+ T L G + R+D Sbjct: 327 GKVAVVTGAGSGIGRCAALAFAREGATIVACDIDLASAER-TALLIGLTGAQ-AHAKRVD 384 Query: 252 VTDYPQFEEAFVMTVEEFNRIDIVINNAGF--------MNDRLWELEVDVNLNGVIRGTL 407 V + E D+VINNAG + R WE + VNL GVI G+ Sbjct: 385 VGSADEMEALATWVGSALGGADVVINNAGIGMAGGILDTSTRHWERILHVNLWGVIHGSR 444 Query: 408 LAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTGV 587 L + M G GG IVNTAS A P P Y T A++ L+ + + G+ Sbjct: 445 LFAQQMA--ARGTGGHIVNTASAAAFGPSRDLPAYATTKAAVLMLSECM--RAELAEQGI 500 Query: 588 RCLVVCPGLTDSGLV 632 VCPG ++G++ Sbjct: 501 GVTAVCPGFAETGIM 515 >UniRef50_Q2IEG2 Cluster: Short-chain dehydrogenase/reductase SDR; n=9; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Anaeromyxobacter dehalogenans (strain 2CP-C) Length = 244 Score = 87.4 bits (207), Expect = 3e-16 Identities = 62/193 (32%), Positives = 91/193 (47%), Gaps = 8/193 (4%) Frame = +3 Query: 75 KVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCRLDV 254 KV LITGA+SGIG A + L ++GA+V L +ER +T ++ + G+ + LDV Sbjct: 7 KVVLITGASSGIGEATARLLAERGARVLLGARRTERLGTITSEILASGGQADQR--ALDV 64 Query: 255 TDYPQFEEAFVMTVEEFNRIDIVINNAGFM--------NDRLWELEVDVNLNGVIRGTLL 410 T + E F R+D+++NNAG M W +DVN+ GV+ G Sbjct: 65 TSLEDMQRFVAFARERFGRVDVIVNNAGVMPLSPLSALKVDEWNRMIDVNIRGVLHGIAA 124 Query: 411 AYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTGVR 590 M G +VN +S + +Y AT YA+V +T D T VR Sbjct: 125 TLPLMEAQGSGH---VVNVSSIGGHVTFPGSAVYCATKYAVVAIT----DSLRQETTKVR 177 Query: 591 CLVVCPGLTDSGL 629 + PG+T+S L Sbjct: 178 ATTISPGVTESEL 190 >UniRef50_Q2GA85 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Novosphingobium aromaticivorans DSM 12444|Rep: Short-chain dehydrogenase/reductase SDR - Novosphingobium aromaticivorans (strain DSM 12444) Length = 310 Score = 87.4 bits (207), Expect = 3e-16 Identities = 61/198 (30%), Positives = 96/198 (48%), Gaps = 11/198 (5%) Frame = +3 Query: 63 DLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFC 242 D G+ A +TG A+G+G+ +LL QG KV++ DI + ++ L ++ V+ Sbjct: 3 DFAGRTAFVTGGANGVGIGLVRQLLNQGCKVAIADIRQDSIDKALATLEAEGSGPEVMGV 62 Query: 243 RLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF--------MNDRLWELEVDVNLNGVIR 398 +LDV F+ A F + I+ NNAG + W+ + VNL+GV+ Sbjct: 63 QLDVASREGFKMAADEVEARFGPVSILCNNAGVNLFQPIEESSYDDWDWLLGVNLHGVVN 122 Query: 399 G-TLLAYRFMGKDRGGQ--GGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYH 569 G T R + + + G+ GG +VNTAS A S IY T +A+ GL+ + Y Sbjct: 123 GVTTFVPRMVERVKAGEQKGGHVVNTASMAAFLAAGSPGIYNTTKFAVRGLSESL--HYS 180 Query: 570 VNVTGVRCLVVCPGLTDS 623 + + V+CPGL S Sbjct: 181 LLKYEIGVSVLCPGLVKS 198 >UniRef50_Q2G760 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Novosphingobium aromaticivorans DSM 12444|Rep: Short-chain dehydrogenase/reductase SDR precursor - Novosphingobium aromaticivorans (strain DSM 12444) Length = 279 Score = 87.4 bits (207), Expect = 3e-16 Identities = 71/209 (33%), Positives = 100/209 (47%), Gaps = 26/209 (12%) Frame = +3 Query: 63 DLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFC 242 D+KG+ AL+TGAASGIGLAY+E + + GA V+L DID+E E+ +L ++ V Sbjct: 8 DIKGRSALVTGAASGIGLAYAEAMAEAGAAVTLTDIDAEGAEREAARLRAE--GYEVRAE 65 Query: 243 RLDVTDYPQFEEAFVMTVEEFNRIDIVINN------AGFMN---------------DRLW 359 +LDV+D+ AF + + +DI N AGF N + W Sbjct: 66 KLDVSDWDNVAAAFDAHDKAYGGLDICFANAGIDTGAGFWNPAGHRNPEGQVDTYDHKRW 125 Query: 360 ELEVDVNLNGVIRGTLLAYRFM---GKDRGGQGGVIVNTASTA--FARPQVSTPIYTATN 524 + + +NLNGV A R M G+ G GG IV TAS A P V P Y Sbjct: 126 DRSIQINLNGVFYTVSNAVRIMKKEGRANGRTGGSIVTTASNAGLVTEPIVGLP-YMPAK 184 Query: 525 YAIVGLTRAYGDQYHVNVTGVRCLVVCPG 611 ++ + RA G + G+R + PG Sbjct: 185 AGVLHMVRALG--LELAEFGIRINAIAPG 211 >UniRef50_Q0SI88 Cluster: Short chain dehydrogenase; n=2; Actinomycetales|Rep: Short chain dehydrogenase - Rhodococcus sp. (strain RHA1) Length = 267 Score = 87.4 bits (207), Expect = 3e-16 Identities = 68/200 (34%), Positives = 97/200 (48%), Gaps = 11/200 (5%) Frame = +3 Query: 63 DLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFC 242 DL G+ AL+TG A G+G + L GA V + D+ E G + + K G + F Sbjct: 5 DLAGRKALVTGGAKGLGAGMAAALADAGAAVVIGDVLEEEGRATADSVG-KTG-VDTGFV 62 Query: 243 RLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF-MNDRLWELE-------VDVNLNGVIR 398 +LDVTD +E A TVE+ +D+++NNAG ++ + +++ +VN+ GV Sbjct: 63 KLDVTDDGNWERAVAATVEQLGGLDLLVNNAGIEISSLVVDIDPADIRRMCEVNILGVAL 122 Query: 399 GTLLAYRFMGK-DRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVN 575 G R M G GG IVN +S A P Y+AT A+ LTR + Sbjct: 123 GLKHGLRAMRPGGAAGSGGAIVNVSSVAATIPFPGIAGYSATKSAVDRLTRVAAQEAGKL 182 Query: 576 VTGVRCLVVCPGL--TDSGL 629 GVR V PGL T+ GL Sbjct: 183 GYGVRVNCVYPGLVATEMGL 202 >UniRef50_A1ATN3 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Pelobacter|Rep: Short-chain dehydrogenase/reductase SDR - Pelobacter propionicus (strain DSM 2379) Length = 283 Score = 87.4 bits (207), Expect = 3e-16 Identities = 64/214 (29%), Positives = 104/214 (48%), Gaps = 15/214 (7%) Frame = +3 Query: 57 NMDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVL 236 NM L GKVA+ITGA GIG A + L GA + + D++ + +V E++ ++ G+ L Sbjct: 18 NMKLDGKVAIITGAGRGIGRAIALRLGADGAAMVVSDVNGDNATKVAEEIKARGGKAMAL 77 Query: 237 FCRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRL--------WELEVDVNLNGV 392 R DVT ++ V + R+DI++ NAG N ++ W+ + VN G Sbjct: 78 --RTDVTSEADVKDLIDTAVRQHGRLDIMVANAGIANIKMSIEMTGAEWDQIMAVNTKGA 135 Query: 393 IRGTLLAYRFMGK----DRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGD 560 +A R M K + G GG I+N AS A Y+A+ +A+ G T+A Sbjct: 136 FLCDTMAARQMIKQGHSETPGSGGKIINCASIAAHSGFSILAAYSASKFAVRGFTQALAK 195 Query: 561 Q---YHVNVTGVRCLVVCPGLTDSGLVXDLDKQL 653 + Y +NV CPG+ + + +D+++ Sbjct: 196 ELGPYKINVN-----AYCPGIVGTDMWTLIDEKM 224 >UniRef50_Q9FX95 Cluster: ARP protein; n=8; Magnoliophyta|Rep: ARP protein - Arabidopsis thaliana (Mouse-ear cress) Length = 629 Score = 87.4 bits (207), Expect = 3e-16 Identities = 68/220 (30%), Positives = 104/220 (47%), Gaps = 19/220 (8%) Frame = +3 Query: 60 MDLK-GKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTE-------KLASK 215 M++K G AL+TG ASGIG A L ++G V++ D E+G++ T K Sbjct: 1 MEIKPGLSALVTGGASGIGRALCLALAEKGVFVTVADFSEEKGQETTSLVREANAKFHQG 60 Query: 216 YGRKNVLFCRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAG------FMND-----RLWE 362 + +F + DVT+ AF + F +DI INNAG F D + W+ Sbjct: 61 LSFPSAIFVKCDVTNRGDLLAAFDKHLATFGTLDICINNAGISTPLRFDKDDTDGSKSWK 120 Query: 363 LEVDVNLNGVIRGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGL 542 ++V+L V+ GT LA + M + + GVI+N S A P PIY A+ +V Sbjct: 121 HTINVDLIAVVEGTQLAIKAMKAKQ--KPGVIINMGSAAGLYPMPVDPIYAASKAGVVLF 178 Query: 543 TRAYGDQYHVNVTGVRCLVVCPGLTDSGLVXDLDKQLMSS 662 TR+ + G+R V+CP + L +D ++ S Sbjct: 179 TRSLA---YYRRQGIRINVLCPEFIKTDLAEAIDASILES 215 >UniRef50_A2QB60 Cluster: Catalytic activity: precursor; n=1; Aspergillus niger|Rep: Catalytic activity: precursor - Aspergillus niger Length = 262 Score = 87.4 bits (207), Expect = 3e-16 Identities = 65/218 (29%), Positives = 108/218 (49%), Gaps = 19/218 (8%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQG-AKVSLCDIDSERGEQVTEKLASKYGRKNVL 236 M L+G VA ITGAASGIG A + L + G +++++ DI+ + + + +++ VL Sbjct: 1 MMLQG-VAFITGAASGIGKATAYALARHGVSQLAIADINFAAAQDTAQDIEARFSGVRVL 59 Query: 237 FCRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRL---------WELEVDVNLNG 389 +DVTD +A TV++F RID +N+AG WE + VNL+G Sbjct: 60 PLNIDVTDPVSIHKAVSETVQQFERIDYAVNSAGIAGSMAYSGDHEIADWEKTLGVNLHG 119 Query: 390 VIRGTLLAYR-FMGKDRGGQG-----GVIVNTAST-AFARPQVSTPI--YTATNYAIVGL 542 V + + MG+++ GVIVN AS + P+ YTA + +VG+ Sbjct: 120 VWMSSREEIKVMMGQEKRDDSPRSSRGVIVNVASAYGLVATPANIPLVSYTAAKHGVVGM 179 Query: 543 TRAYGDQYHVNVTGVRCLVVCPGLTDSGLVXDLDKQLM 656 ++A D G+R +CPG + ++ + ++M Sbjct: 180 SKA--DAIVYAPLGIRINAICPGYVQTPMIDQMADEVM 215 >UniRef50_A7DQI5 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep: Short-chain dehydrogenase/reductase SDR precursor - Candidatus Nitrosopumilus maritimus SCM1 Length = 269 Score = 87.4 bits (207), Expect = 3e-16 Identities = 68/217 (31%), Positives = 107/217 (49%), Gaps = 11/217 (5%) Frame = +3 Query: 12 LSTSHF*ARCFYSSINMDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQ 191 L S + R F I + L GKVAL+TG + GIG A ++ L + GA V++ ER E+ Sbjct: 8 LKKSIYKLRIFLLKI-LSLSGKVALVTGGSRGIGFATAKVLSENGANVAITGKVQERLEK 66 Query: 192 VTEKLASKYGRKNVLFCRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF---------M 344 V+ ++++ + DV + A VE+F R+DI++NNAG + Sbjct: 67 VSSEISNSFA------IVADVRKTEDVKNAIKKIVEKFGRLDILVNNAGVFPKIKKLHEI 120 Query: 345 NDRLWELEVDVNLNGVIRGTLLAYRFMGKDRGGQGGVIVNTASTA--FARPQVSTPIYTA 518 +D W +DVNL G R T A + K G I+N +S A A + Y+A Sbjct: 121 DDEEWNEVLDVNLTGQFRVTKEAIPHLQKTSGS----IINISSDAGLKAYQGFNADAYSA 176 Query: 519 TNYAIVGLTRAYGDQYHVNVTGVRCLVVCPGLTDSGL 629 T A++ LT+ + +Y + V C +CPG+ D+ + Sbjct: 177 TKAALIVLTKCWALEYSKDKIRVNC--ICPGVVDTDM 211 >UniRef50_Q2UEK6 Cluster: Dehydrogenases with different specificities; n=2; Aspergillus|Rep: Dehydrogenases with different specificities - Aspergillus oryzae Length = 261 Score = 87.0 bits (206), Expect = 4e-16 Identities = 58/191 (30%), Positives = 93/191 (48%), Gaps = 9/191 (4%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 L+GKVA++TGA SGIG + L GA V + + + G++ K++++ G + LF Sbjct: 10 LQGKVAIVTGAGSGIGRETALCLANAGANVVVAEANETTGKETAAKVSAQTGSRG-LFIL 68 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF---------MNDRLWELEVDVNLNGVIR 398 DV+ + + T+E F R+DI +NNA +++ W+ + VNL GV Sbjct: 69 TDVSRSESVQAMVIATIEAFGRLDIAVNNAALHPDASPIAELHEDHWQKIIGVNLVGV-- 126 Query: 399 GTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNV 578 L + + G GG I+N +S RPQ Y A + I GLT+ + + Sbjct: 127 AFCLKWELQQMIQQGGGGSIINISSATINRPQEKMSAYIAAKHGITGLTQTAAVENGRH- 185 Query: 579 TGVRCLVVCPG 611 G+R + PG Sbjct: 186 -GIRVNALAPG 195 >UniRef50_A0RX79 Cluster: Short-chain alcohol dehydrogenase; n=1; Cenarchaeum symbiosum|Rep: Short-chain alcohol dehydrogenase - Cenarchaeum symbiosum Length = 252 Score = 87.0 bits (206), Expect = 4e-16 Identities = 62/198 (31%), Positives = 100/198 (50%), Gaps = 7/198 (3%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLF 239 M L+GKVA++TGA+S IG + L ++GAKV L R + + ++ Sbjct: 1 MRLEGKVAVVTGASSDIGASIVRRLAEEGAKVVLL---GRRPDALEAARRVSGHEESTAS 57 Query: 240 CRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDR-----LWELEVDVNLNGVIRGT 404 DVTD Q + VE + RIDI++N AG ++D + ++V ++G + G Sbjct: 58 IPCDVTDEGQLAQMADRVVEAYGRIDILVNGAGSIHDPKHFHVMPIMDVKKMIHGNVLGV 117 Query: 405 LLAYRFMGKDRGGQGGVIVNTASTAFAR--PQVSTPIYTATNYAIVGLTRAYGDQYHVNV 578 LL R + GGVI+N S + R P+V Y++T A+V T++ +Y Sbjct: 118 LLPTRAVLGKMMDTGGVIINIGSISAERAIPRVHLAAYSSTKAAVVMFTKSIAVEYARR- 176 Query: 579 TGVRCLVVCPGLTDSGLV 632 +RC + PG+ DSG++ Sbjct: 177 -NIRCNCINPGIVDSGMI 193 >UniRef50_Q2JDM5 Cluster: Short-chain dehydrogenase/reductase SDR; n=5; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Frankia sp. (strain CcI3) Length = 259 Score = 86.6 bits (205), Expect = 6e-16 Identities = 60/199 (30%), Positives = 97/199 (48%), Gaps = 8/199 (4%) Frame = +3 Query: 54 INMDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNV 233 +++ L GKV L+TG ++G+G A L +GA+V+ C D R +V + ++ G V Sbjct: 1 MDLQLAGKVVLVTGGSNGLGAALVRTLAAEGARVAFCGRDETRLREVAGQ--AQAGGGEV 58 Query: 234 LFCRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAG------FMN--DRLWELEVDVNLNG 389 L DVT E V+ +N +D ++NNAG F N D +W ++++ L+ Sbjct: 59 LAVPADVTSITDLERFVATAVDRWNAVDALVNNAGASAGGTFENQTDEVWNADLELKLHA 118 Query: 390 VIRGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYH 569 IR + L ++ R GG IVN+ S A P + + T A + LT+A + Sbjct: 119 AIRASRLVLPYL---RRAGGGGIVNSLSVAARAPSAGSTPTSVTRAAGLALTKALSKE-- 173 Query: 570 VNVTGVRCLVVCPGLTDSG 626 + +R V GL +SG Sbjct: 174 LGPDRIRVNAVLIGLVESG 192 >UniRef50_Q3WGS3 Cluster: Short-chain dehydrogenase/reductase SDR; n=5; Frankia sp. EAN1pec|Rep: Short-chain dehydrogenase/reductase SDR - Frankia sp. EAN1pec Length = 306 Score = 86.6 bits (205), Expect = 6e-16 Identities = 64/193 (33%), Positives = 89/193 (46%), Gaps = 9/193 (4%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 L GKVA+ITGA SGIG + + ++GA+V D+ E L +K + Sbjct: 64 LDGKVAVITGAGSGIGRSAAFLFAREGARVVCADVSGR------EALTAKAVGDGAIAVH 117 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF---------MNDRLWELEVDVNLNGVIR 398 +DVT E V+ F ++D++ NNAGF + ++ + VN+ GV Sbjct: 118 VDVTSTEDIERMITTAVDRFGKLDVLYNNAGFTGPIVPLAEAGEDYFDAVMAVNVKGVYL 177 Query: 399 GTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNV 578 G A M G GG I+NTAS A +Y AT A+V LTR+ Y Sbjct: 178 GMKAAIPVM---LAGGGGSIINTASAAGLVGWKGLAVYAATKGAVVQLTRSAALDYAAK- 233 Query: 579 TGVRCLVVCPGLT 617 G+R VCPG T Sbjct: 234 -GIRVNAVCPGAT 245 >UniRef50_Q3WEN2 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Frankia sp. EAN1pec|Rep: Short-chain dehydrogenase/reductase SDR precursor - Frankia sp. EAN1pec Length = 312 Score = 86.6 bits (205), Expect = 6e-16 Identities = 62/192 (32%), Positives = 91/192 (47%), Gaps = 5/192 (2%) Frame = +3 Query: 72 GKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCRLD 251 GKV L+TGA SGIG A + ++GA+V C E G +V E++ + G + R D Sbjct: 58 GKVVLVTGATSGIGRAAAIAFAREGARVGFCGRREELGRRVEEEIRAAGG--EATYTRAD 115 Query: 252 VTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDR-LWELEV---DVNLNGVIRGTLLAYR 419 V D Q E + + R+D+ +NNAG + L E+ V D + RG LA + Sbjct: 116 VRDPAQVESFVAGVADRYGRLDVALNNAGTQIVKPLHEMTVEEWDDTAHTNTRGVFLAIK 175 Query: 420 F-MGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTGVRCL 596 + + R GGVI+ T S + Y+A+ + GL R Y +R Sbjct: 176 YEVPPMRESGGGVILVTGSANEFASRPGLGAYSASKGGVTGLVRTAALDY--GQDNIRVA 233 Query: 597 VVCPGLTDSGLV 632 + PG TD+GLV Sbjct: 234 ALSPGTTDTGLV 245 >UniRef50_Q0RLA9 Cluster: Putative short chain dehydrogenase; n=1; Frankia alni ACN14a|Rep: Putative short chain dehydrogenase - Frankia alni (strain ACN14a) Length = 271 Score = 86.6 bits (205), Expect = 6e-16 Identities = 59/190 (31%), Positives = 89/190 (46%), Gaps = 9/190 (4%) Frame = +3 Query: 69 KGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCRL 248 +G+VA++TGAASGIG +E L +G V L D+ ++ E+ LA+ L Sbjct: 5 QGQVAVVTGAASGIGYGLAEALAARGVHVVLSDVQTDAVERAAATLAA--AGATTLAVAA 62 Query: 249 DVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMND---------RLWELEVDVNLNGVIRG 401 DV D Q T++ F R+D+V NNAG ++ W +DV L GV+ G Sbjct: 63 DVGDADQVGALAAATIDRFGRVDLVCNNAGVVSRPAPMWEQGLASWRWLIDVALLGVVHG 122 Query: 402 TLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVT 581 + F+ GG ++NTAS P + Y A +A++GLT + Sbjct: 123 ---VHHFVPHLIRQGGGHVLNTASVGGLMPLPTLTPYNAVKHAVIGLTETLDLELRAVAP 179 Query: 582 GVRCLVVCPG 611 + V+CPG Sbjct: 180 TLGASVLCPG 189 >UniRef50_Q0FK49 Cluster: FabG3_1; n=1; Roseovarius sp. HTCC2601|Rep: FabG3_1 - Roseovarius sp. HTCC2601 Length = 249 Score = 86.6 bits (205), Expect = 6e-16 Identities = 68/203 (33%), Positives = 95/203 (46%), Gaps = 9/203 (4%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDI-DSERGEQVTEKLASKYGRKNVL 236 MD+ GKV LI+GAA G+G + + GA V L D+ D E LA G L Sbjct: 1 MDVTGKVVLISGAARGMGAHEARRFAEAGACVILGDVLDDE-----VRALAEDLGDARAL 55 Query: 237 FCRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFM--------NDRLWELEVDVNLNGV 392 LDV+ +E A V F +ID+++NNAG + +D WE + +NL G Sbjct: 56 AVPLDVSRSEDWEGAVAAGVARFGQIDVLVNNAGILRFSNIETCSDEEWEKVLSINLGGA 115 Query: 393 IRGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHV 572 +G M R G G I+N +STA + Y + + I GLTRA + Sbjct: 116 FKGIRAVLPVM--KRNGSGS-IINISSTAGLKAFGGVSAYVTSKFGIRGLTRAAAVELAG 172 Query: 573 NVTGVRCLVVCPGLTDSGLVXDL 641 + G+R V PG D+ +V DL Sbjct: 173 H--GIRVNSVHPGNIDTDMVEDL 193 >UniRef50_A7AZH2 Cluster: Putative uncharacterized protein; n=1; Ruminococcus gnavus ATCC 29149|Rep: Putative uncharacterized protein - Ruminococcus gnavus ATCC 29149 Length = 276 Score = 86.6 bits (205), Expect = 6e-16 Identities = 61/194 (31%), Positives = 88/194 (45%), Gaps = 9/194 (4%) Frame = +3 Query: 75 KVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCRLDV 254 K+ L+TGA SGIG A + K+GA V + ERG V + G+ + C DV Sbjct: 14 KIMLVTGATSGIGRAVAIRAAKEGATVVAVGRNEERGAAVVAAMEEAGGKGEFMKC--DV 71 Query: 255 TDYPQFEEAFVMTVEEFNRIDIVINNAGF---------MNDRLWELEVDVNLNGVIRGTL 407 ++ + F E++ ++D+ +NNAG + D W +D NLN Sbjct: 72 SNKDAVKALFAEIQEKYGKLDVAVNNAGIVGASKTVEELEDDDWFQVIDANLN----SCF 127 Query: 408 LAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTGV 587 R K GG IVN +S A R S Y A+ +A+ GLT+A Y G+ Sbjct: 128 FCCREEVKLMQPSGGAIVNVSSVAGMRGFPSAAAYVASKHAVSGLTKAVAVDYATK--GI 185 Query: 588 RCLVVCPGLTDSGL 629 C +CP TD+ L Sbjct: 186 TCNAICPAGTDTPL 199 >UniRef50_A0PSR4 Cluster: Short-chain dehydrogenase; n=1; Mycobacterium ulcerans Agy99|Rep: Short-chain dehydrogenase - Mycobacterium ulcerans (strain Agy99) Length = 282 Score = 86.6 bits (205), Expect = 6e-16 Identities = 61/197 (30%), Positives = 103/197 (52%), Gaps = 8/197 (4%) Frame = +3 Query: 63 DLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFC 242 DL G+V ITGA SGIG + ++GA ++LCDI ++ T + A +G +V+ Sbjct: 12 DLAGRVVAITGAGSGIGRELALLCAQRGADLALCDI-NDTAVADTAQTARGFGH-DVITR 69 Query: 243 RLDVTDYPQFEEAFVMTVEEFNRIDIVINNA------GFMND--RLWELEVDVNLNGVIR 398 R+DV+D Q T+ F +D+++NNA GF++ + W+ V +N+ GV+ Sbjct: 70 RVDVSDPEQMTAFADATLGHFGGVDLLVNNAGVGLIGGFLDTSRKDWDWLVSINVMGVVH 129 Query: 399 GTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNV 578 G M G+GG +VN +S A + Y+AT +A++GL+ A + + Sbjct: 130 GCEAFLPAM--IESGRGGHVVNLSSAAGLLANPALSAYSATKFAVLGLSEALRIELEPHR 187 Query: 579 TGVRCLVVCPGLTDSGL 629 GV +CPG+ ++ + Sbjct: 188 IGV--TAICPGVINTAI 202 >UniRef50_A0NRG9 Cluster: Acetoin (Diacetyl) reductase; n=4; Rhodobacterales|Rep: Acetoin (Diacetyl) reductase - Stappia aggregata IAM 12614 Length = 265 Score = 86.6 bits (205), Expect = 6e-16 Identities = 68/211 (32%), Positives = 107/211 (50%), Gaps = 14/211 (6%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTE---KLASKYGRKNVL 236 + G+ ++TGAA GIG A E L+ +GA V DI+ E+ + V E + A++ G V Sbjct: 4 VSGRSCIVTGAARGIGRAIGEALINEGADVCFADINGEQAQAVCEANRERATEAG-AGVT 62 Query: 237 FCRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF---MN-----DRLWELEVDVNLNGV 392 + ++DVTD Q TVE F ++D+ NNAG MN + W + VN G Sbjct: 63 WAKVDVTDRDQVRAMIDKTVETFGKLDVKFNNAGVNKPMNFLDVTEDNWNFIMGVNGLGC 122 Query: 393 IRGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYG---DQ 563 + G A R M G GG I+NTAS A + + Y A+ +A+V LT++ + Sbjct: 123 LIGMQEAARQMIAQ--GTGGKIINTASIASRQGFDNVAPYCASKWAVVSLTQSGARDLAR 180 Query: 564 YHVNVTGVRCLVVCPGLTDSGLVXDLDKQLM 656 +++ VTG PG+ + + +D+ L+ Sbjct: 181 HNITVTG-----FAPGVVATEMWEQVDRDLL 206 >UniRef50_A0K1M9 Cluster: Short-chain dehydrogenase/reductase SDR; n=6; Actinomycetales|Rep: Short-chain dehydrogenase/reductase SDR - Arthrobacter sp. (strain FB24) Length = 320 Score = 86.6 bits (205), Expect = 6e-16 Identities = 56/189 (29%), Positives = 88/189 (46%), Gaps = 6/189 (3%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLF 239 M L GKVA++TG+ G+GLAY+ EL +QGA V + D+D+E + + + G+ + Sbjct: 1 MSLSGKVAIVTGSGRGLGLAYARELARQGAAVVINDVDAEVAAEAVRTIEADGGKATAVV 60 Query: 240 CRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMND----RLWELEVDVNLNGVIRGTL 407 + T+ + + VE F R+DI++ NAG + D ++ + + D +N +RGT Sbjct: 61 APVGSTEAAR--QLVQAAVENFGRLDILVTNAGILRDKSLLKMTDEDFDAVINVHLRGTF 118 Query: 408 LAYR--FMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVT 581 R F G G I+ S R Y A IVG+ R + + Sbjct: 119 TCVREAFAYFKENGVAGRIITIGSPTGQRGNFGQTNYAAAKAGIVGMVRTWA--LEMKKA 176 Query: 582 GVRCLVVCP 608 GV V P Sbjct: 177 GVTANAVIP 185 >UniRef50_Q9LW34 Cluster: Alcohol dehydrogenase-like protein; n=6; Magnoliophyta|Rep: Alcohol dehydrogenase-like protein - Arabidopsis thaliana (Mouse-ear cress) Length = 306 Score = 86.6 bits (205), Expect = 6e-16 Identities = 62/193 (32%), Positives = 98/193 (50%), Gaps = 11/193 (5%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 L+GKVALITG ASG+G A + E L+ GA+V + D+D+E G + ++L S+ F R Sbjct: 41 LEGKVALITGGASGLGKATASEFLRHGARVVIADLDAETGTKTAKELGSE-----AEFVR 95 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRL-----------WELEVDVNLNGV 392 DVT A MTVE + ++D++ NNAG + +E + +N+ GV Sbjct: 96 CDVTVEADIAGAVEMTVERYGKLDVMYNNAGIVGPMTPASISQLDMTEFERVMRINVFGV 155 Query: 393 IRGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHV 572 + G A +FM R G I+ T+S A ++ YT + + G+ ++ + Sbjct: 156 VSGIKHAAKFMIPAR---SGCILCTSSVAGVTGGLAPHSYTISKFTTPGIVKSAASELCE 212 Query: 573 NVTGVRCLVVCPG 611 + GVR + PG Sbjct: 213 H--GVRINCISPG 223 >UniRef50_Q930M2 Cluster: Putative; n=4; Bacteria|Rep: Putative - Rhizobium meliloti (Sinorhizobium meliloti) Length = 249 Score = 86.2 bits (204), Expect = 8e-16 Identities = 62/197 (31%), Positives = 97/197 (49%), Gaps = 12/197 (6%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 L GK+AL+TGA+SGIG A + +L + GAKV + +++ E + +K+ +K G L Sbjct: 4 LNGKIALVTGASSGIGAATAAKLAEAGAKVGIAARRTDKLEDLKKKIEAKGG--EALVIE 61 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMN----DRL----WELEVDVNLNGVIRG 401 +DV D E V+ + IDI++NNAG M D+ W+ VDVN+ G++ Sbjct: 62 MDVVDTTSVEAGVKKLVDAYGSIDILVNNAGLMPLSDIDQFKVDEWQRMVDVNVKGLLNT 121 Query: 402 TLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIV----GLTRAYGDQYH 569 T M K G + N +S A + +Y AT +A+ GL G ++ Sbjct: 122 TAAVLPQMIKQHSGH---VFNMSSIAGRKVFKGLSVYCATKHAVTAFSDGLRMEVGQKHG 178 Query: 570 VNVTGVRCLVVCPGLTD 620 + VT ++ V L D Sbjct: 179 IRVTCIQPGAVATELYD 195 >UniRef50_Q89P10 Cluster: Oxidoreductase; n=1; Bradyrhizobium japonicum|Rep: Oxidoreductase - Bradyrhizobium japonicum Length = 248 Score = 86.2 bits (204), Expect = 8e-16 Identities = 71/201 (35%), Positives = 95/201 (47%), Gaps = 9/201 (4%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 L+GKVA+ITGA SGIG A + +GAKV L D+ +E G + LA+ F Sbjct: 4 LEGKVAVITGAGSGIGAAIARLFAVEGAKVLLGDL-AEGGAALAAGLAADGHAAG--FQH 60 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRL---------WELEVDVNLNGVIR 398 +DVTD E V F R+DI++ NAG + W +DV+L GV Sbjct: 61 VDVTDEASVAELMQAAVTLFGRLDILVANAGIPERKSPIHELDLVDWRRVIDVDLTGVAI 120 Query: 399 GTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNV 578 A M R GG IVN AS Q ++ Y+A A+V LTR+ Y + Sbjct: 121 CNKFAAGIM---RATGGGAIVNMASILAHVGQENSNAYSAAKAAVVNLTRSVALTYALQ- 176 Query: 579 TGVRCLVVCPGLTDSGLVXDL 641 G+R V PG D+ L+ L Sbjct: 177 -GIRANCVSPGYVDTPLLAKL 196 >UniRef50_Q3WJ78 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Frankia sp. EAN1pec|Rep: Short-chain dehydrogenase/reductase SDR - Frankia sp. EAN1pec Length = 250 Score = 86.2 bits (204), Expect = 8e-16 Identities = 69/204 (33%), Positives = 100/204 (49%), Gaps = 9/204 (4%) Frame = +3 Query: 63 DLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFC 242 DL+GKVA++TGAA+GIG+A + + +GAKV + DID+ G+ V +L + F Sbjct: 6 DLEGKVAIVTGAANGIGVAIATRFVTEGAKVVIADIDA-GGQGVAAELGER-----ATFF 59 Query: 243 RLDVTDYPQFEEAFVMTVEEFNRIDIVINNAG-------FMNDRLWELE--VDVNLNGVI 395 DV+D Q + T+ F + ++ NNAG F++D L + E V V+L GV+ Sbjct: 60 STDVSDPVQTQALVDFTIRHFGGLHVLCNNAGVSGGLRRFLDDDLRDFERVVAVDLYGVM 119 Query: 396 RGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVN 575 + A R M D G GG IVN AS A P + Y A +V TR V Sbjct: 120 ACSRSAARHM-VDHG--GGAIVNIASGAGITPGIGMLPYRAAKAGVVQFTRCLA--VEVG 174 Query: 576 VTGVRCLVVCPGLTDSGLVXDLDK 647 G+R + P + + DK Sbjct: 175 EHGIRANCIAPANISTDINAAFDK 198 >UniRef50_Q1U845 Cluster: NAD-dependent epimerase/dehydratase:Short-chain dehydrogenase/reductase SDR; n=3; Bacteria|Rep: NAD-dependent epimerase/dehydratase:Short-chain dehydrogenase/reductase SDR - Lactobacillus reuteri 100-23 Length = 246 Score = 86.2 bits (204), Expect = 8e-16 Identities = 61/200 (30%), Positives = 95/200 (47%), Gaps = 8/200 (4%) Frame = +3 Query: 75 KVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCRLDV 254 + +ITG SGIGLA ++ LK G L D+E+G QV +L Y V+F + D+ Sbjct: 2 QTVVITGGTSGIGLATADVFLKNGWNTVLIGRDAEKGMQVERQLGETYSPAQVVFIQADI 61 Query: 255 TDYPQFEEAFVMTVEEFNRIDIVINNAGFM--------NDRLWELEVDVNLNGVIRGTLL 410 + + E +T+ +F +D ++NNAG + ++ W DV++ G L+ Sbjct: 62 SKSSEVEHVKQITLNKFKTVDAIVNNAGIVIHGEVHETSEEDWNKIFDVDVKGTF---LI 118 Query: 411 AYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTGVR 590 + F+ G IVN +S + + Y A AI+ +TRA Y N +R Sbjct: 119 SKAFLPTMIEQDHGSIVNISSVSGMAGDRAMVAYNAAKGAIINMTRAMAIDYGKN--NIR 176 Query: 591 CLVVCPGLTDSGLVXDLDKQ 650 VV PG T++ L DKQ Sbjct: 177 VNVVAPGPTNTPLFHQ-DKQ 195 >UniRef50_Q13HC1 Cluster: Putative short-chain dehydrogenase/reductase; n=1; Burkholderia xenovorans LB400|Rep: Putative short-chain dehydrogenase/reductase - Burkholderia xenovorans (strain LB400) Length = 277 Score = 86.2 bits (204), Expect = 8e-16 Identities = 64/193 (33%), Positives = 95/193 (49%), Gaps = 9/193 (4%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 LK +VAL+TGAASGIG A + + ++GA V L D+D G+ + +L ++ F Sbjct: 5 LKDRVALVTGAASGIGAATARLMAQEGAFVVLADVDEHAGQALAREL------RDATFAY 58 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFM---------NDRLWELEVDVNLNGVIR 398 DV+ Q A + R+D ++NNAGF+ + W + V L+GV Sbjct: 59 TDVSVEAQVAAAVDEALRLHGRLDCMVNNAGFVGAYGSILETSAAAWHATLGVLLDGVFY 118 Query: 399 GTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNV 578 G A R M K G I++ ASTA + YT+ +A++GLTR+ + + Sbjct: 119 GIKHAARAMVKQ---GSGCILSVASTAGVMGGLGPHAYTSAKHAVIGLTRSAASE--LAP 173 Query: 579 TGVRCLVVCPGLT 617 GVR V PG T Sbjct: 174 RGVRVNAVAPGTT 186 >UniRef50_Q0RIJ2 Cluster: Putative short chain dehydrogenase/reductase; n=1; Frankia alni ACN14a|Rep: Putative short chain dehydrogenase/reductase - Frankia alni (strain ACN14a) Length = 261 Score = 86.2 bits (204), Expect = 8e-16 Identities = 72/208 (34%), Positives = 105/208 (50%), Gaps = 13/208 (6%) Frame = +3 Query: 72 GKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCRLD 251 G+VA ITG A+G GLA++ EL ++GA + L DID+ E+ L ++ G VL R D Sbjct: 16 GRVAFITGGAAGFGLAFARELAERGASIVLADIDAAAAERSAAAL-TEAGHP-VLPVRCD 73 Query: 252 VTDYPQFEEAFVMTVEEFNRIDIVINNAG------------FMNDRLWELEVDVNLNGVI 395 V + A VE F IDI++NNAG D + EL DVN+ GV+ Sbjct: 74 VAAEDTVDAAVAAAVERFGGIDILVNNAGRHLTRYNLPFQTLARDDVREL-FDVNVMGVV 132 Query: 396 RGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVN 575 +L A M RG GG I+N +S A + T Y + A+ GLT A+ ++ + Sbjct: 133 NCSLAARPSMAA-RG--GGSIINISSMA---SHLGTSPYAVSKLAVRGLTVAFATEFAPD 186 Query: 576 VTGVRCLVVCPGLTDS-GLVXDLDKQLM 656 +R + PGL D+ + DL +L+ Sbjct: 187 --NIRVNAISPGLMDTESAMADLPAELV 212 >UniRef50_A7DM07 Cluster: Short-chain dehydrogenase/reductase SDR; n=4; Alphaproteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Methylobacterium extorquens PA1 Length = 282 Score = 86.2 bits (204), Expect = 8e-16 Identities = 64/189 (33%), Positives = 91/189 (48%), Gaps = 9/189 (4%) Frame = +3 Query: 72 GKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCRLD 251 GKVA ITGAASGIG A + ++GA+V++ D E E++ ++ G V+ R D Sbjct: 40 GKVAFITGAASGIGRAAAIAFAREGAQVAITDRTEEALERLRAEIEGNGGA--VIAIRCD 97 Query: 252 VTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRL---------WELEVDVNLNGVIRGT 404 V+ A TVE F R+D NNAG N W+ +D+NL G Sbjct: 98 VSLPEDVAAAVARTVERFGRLDCAFNNAGVENKAAPVHEIALDEWDRILDINLRGTF--V 155 Query: 405 LLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTG 584 + + R G GGV+VNT+S A R Y A+ +A++GLT++ Y Sbjct: 156 CMKHEIAQMLRQG-GGVVVNTSSGAGIRGVAGGASYAASKHALIGLTKSAALDY--AKAN 212 Query: 585 VRCLVVCPG 611 +R V PG Sbjct: 213 IRVNAVLPG 221 >UniRef50_A3KJN1 Cluster: Putative 3-oxoacyl-acyl-carrier protein reductase; n=1; Streptomyces ambofaciens ATCC 23877|Rep: Putative 3-oxoacyl-acyl-carrier protein reductase - Streptomyces ambofaciens ATCC 23877 Length = 253 Score = 86.2 bits (204), Expect = 8e-16 Identities = 58/201 (28%), Positives = 94/201 (46%), Gaps = 9/201 (4%) Frame = +3 Query: 72 GKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCRLD 251 G+ ++TGA SGIG A + QG +V L D+D++ E +++ G + D Sbjct: 7 GRSVIVTGAGSGIGRAAALAFAAQGDRVVLADLDAQGAEAAVQEIERAGG--TAVAVAGD 64 Query: 252 VTDYPQFEEAFVMTVEEFNRIDIVINNAGFM---------NDRLWELEVDVNLNGVIRGT 404 +++ + +E F ID+++NNAG M +D WE + VNL Sbjct: 65 LSEQAVVDRVTATALERFGGIDVLVNNAGIMDRMSALADVSDAEWERVLRVNLTAPF--- 121 Query: 405 LLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTG 584 LL + G +VNTAS A R + YTA+ + +VGLT+ Y G Sbjct: 122 LLTRAVLPHMLAAGRGAVVNTASEAGLRGSAAGAAYTASKHGVVGLTKNLAVMYRGR--G 179 Query: 585 VRCLVVCPGLTDSGLVXDLDK 647 +R +CPG T + + D+++ Sbjct: 180 IRANAICPGGTQTAISVDVEQ 200 >UniRef50_A1UD24 Cluster: Short-chain dehydrogenase/reductase SDR; n=27; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Mycobacterium sp. (strain KMS) Length = 275 Score = 86.2 bits (204), Expect = 8e-16 Identities = 62/204 (30%), Positives = 104/204 (50%), Gaps = 20/204 (9%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 L GKVAL++G+ GIG A +E+L +GA+V + D+D+E ++V + + G+ C Sbjct: 6 LDGKVALVSGSGRGIGRAVAEKLAAEGARVVINDLDAEPAKEVVAAIEAAGGQATA--CV 63 Query: 246 LDVTDYPQFEEAFVMT-VEEFNRIDIVINNAGF--------MNDRLWELEVDVNLNG--- 389 VTD P+F + FV T V+ + +DI++NNAG+ M D+ W +DV+L Sbjct: 64 GSVTD-PEFADRFVSTAVDNYGGLDIIVNNAGYTWDSVIQKMTDQQWNDIIDVHLTAPFR 122 Query: 390 VIRGTLLAYRFMGKDRGGQGGV-----IVNTASTAFARPQVSTPIYTATNYAIVGLTRAY 554 ++R + K + GV IVNT+ST+ + Y+ ++G+T+ Sbjct: 123 ILRAAQPVISGLAKKEKAENGVASRRAIVNTSSTSGLQGNPGQVNYSTAKAGLIGMTKTL 182 Query: 555 GDQ---YHVNVTGVRCLVVCPGLT 617 + Y+V V + V+ LT Sbjct: 183 AKEWGRYNVTVNAIAYGVINTRLT 206 >UniRef50_A0JSI8 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=18; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR precursor - Arthrobacter sp. (strain FB24) Length = 263 Score = 86.2 bits (204), Expect = 8e-16 Identities = 69/220 (31%), Positives = 105/220 (47%), Gaps = 19/220 (8%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLF 239 MD+KG VALITG ASG+G A + L GA V L D+ S RGE +L + G +F Sbjct: 1 MDIKGTVALITGGASGLGAATARRLFDAGASVVLVDLPSSRGEAFAAELNAASGAGTAVF 60 Query: 240 CRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFM-------NDRLWELE-----VDVNL 383 DVT Q + A V + IV+N AG D + L+ + +NL Sbjct: 61 VPADVTSEEQVQAAVAAAV-ALGPLRIVVNCAGIATPGKVLGRDGVLPLDTFSRVIQINL 119 Query: 384 NG---VIR---GTLLAYRFMGKDRGG-QGGVIVNTASTAFARPQVSTPIYTATNYAIVGL 542 G VIR + A + + GG + GVI+NTAS A Q+ P Y A+ A+ + Sbjct: 120 VGTFNVIRLAAAAMAATEPVSTELGGPERGVIINTASVAAFDGQIGQPAYAASKGAVAAM 179 Query: 543 TRAYGDQYHVNVTGVRCLVVCPGLTDSGLVXDLDKQLMSS 662 T + ++ +R + + PG+ ++ ++ L ++ S Sbjct: 180 TLPIARELARSL--IRVVTIAPGIFETPMMAGLPQEAQDS 217 >UniRef50_Q56840 Cluster: 2-(R)-hydroxypropyl-CoM dehydrogenase; n=4; Xanthobacter autotrophicus Py2|Rep: 2-(R)-hydroxypropyl-CoM dehydrogenase - Xanthobacter sp. (strain Py2) Length = 250 Score = 86.2 bits (204), Expect = 8e-16 Identities = 64/191 (33%), Positives = 94/191 (49%), Gaps = 8/191 (4%) Frame = +3 Query: 75 KVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCRLDV 254 +VA++TGA+SG GLA + L +G +V+ D+ +E E+ Y K VL R DV Sbjct: 3 RVAIVTGASSGNGLAIATRFLARGDRVAALDLSAETLEETARTHWHAYADK-VLRVRADV 61 Query: 255 TDYPQFEEAFVMTVEEFNRIDIVINNAGFM-NDRLWEL------EVDVNLNGVIRGTLLA 413 D A T+E+F ID+++NNAG N L + D + +RG L Sbjct: 62 ADEGDVNAAIAATMEQFGAIDVLVNNAGITGNSEAGVLHTTPVEQFDKVMAVNVRGIFLG 121 Query: 414 YRFMGKDRGGQG-GVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTGVR 590 R + QG GVIVN AS A YT + A++ LT++ Y +G+R Sbjct: 122 CRAVLPHMLLQGAGVIVNIASVASLVAFPGRSAYTTSKGAVLQLTKSVAVDY--AGSGIR 179 Query: 591 CLVVCPGLTDS 623 C VCPG+ ++ Sbjct: 180 CNAVCPGMIET 190 >UniRef50_Q46UH5 Cluster: Short-chain dehydrogenase/reductase SDR:Glucose/ribitol dehydrogenase; n=1; Ralstonia eutropha JMP134|Rep: Short-chain dehydrogenase/reductase SDR:Glucose/ribitol dehydrogenase - Ralstonia eutropha (strain JMP134) (Alcaligenes eutrophus) Length = 277 Score = 85.8 bits (203), Expect = 1e-15 Identities = 66/193 (34%), Positives = 97/193 (50%), Gaps = 10/193 (5%) Frame = +3 Query: 63 DLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFC 242 D +GK A+ITGAASGIGLA +E L +GA ++L DID+ RG K + GR+ + Sbjct: 12 DFEGKTAIITGAASGIGLALAEALAARGADLALADIDA-RGLDAARKRLAPTGRR-ICTR 69 Query: 243 RLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF--------MNDRLWELEVDVNLNGVIR 398 LDV+ +A RI +V NNAG ++++ W +N+ GVI Sbjct: 70 VLDVSSDADVRDAAAEFEATLGRIHLVFNNAGIDMSGELASLSEQDWTRAFGINVFGVIH 129 Query: 399 GTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPI--YTATNYAIVGLTRAYGDQYHV 572 G + + R G+ V+TAS A P+ Y AT Y++V L+ A + + Sbjct: 130 G--IRHFLPLLRRHGEPAHFVSTASGAGLWVNGDFPMGAYAATKYSVVALSEAL--EQEL 185 Query: 573 NVTGVRCLVVCPG 611 TG+ V+CPG Sbjct: 186 RGTGIGVSVLCPG 198 >UniRef50_Q022W9 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Solibacter usitatus Ellin6076|Rep: Short-chain dehydrogenase/reductase SDR precursor - Solibacter usitatus (strain Ellin6076) Length = 346 Score = 85.8 bits (203), Expect = 1e-15 Identities = 64/216 (29%), Positives = 106/216 (49%), Gaps = 8/216 (3%) Frame = +3 Query: 3 AAKLSTSHF*ARCFYSSINMDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSER 182 +A L+T+ A MD++GKV LITG + G+GLA + ++GAK++LC E Sbjct: 10 SAALATAGIAATVLRRRACMDMRGKVVLITGGSHGLGLALARRFAQEGAKIALCARSEEE 69 Query: 183 GEQVTEKLASKYGRKNVLFCRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMN----D 350 + E +AS+ C DV+D Q E T++ F RID+++NNAG ++ D Sbjct: 70 LRRAREDVASRGAEVFTATC--DVSDRLQVEAVVTATLDRFRRIDVLVNNAGIIHVGPVD 127 Query: 351 RLWELEVDVNLNGVIRGTLLA-YRFMGKDRGGQGGVIVNTASTAFARPQVSTP---IYTA 518 + + + + + GT+ A + RG + IVN S +VS P Y+ Sbjct: 128 AMTIEDFEQAMGVMFWGTVYATMAVLPHMRGRRDQRIVNITSIG---AKVSVPHLLPYSC 184 Query: 519 TNYAIVGLTRAYGDQYHVNVTGVRCLVVCPGLTDSG 626 +A + G + ++ TGV+ + + PGL +G Sbjct: 185 AKFAAAAFSE--GMRAELSGTGVKVVTIAPGLMRTG 218 >UniRef50_A7HWE4 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Parvibaculum lavamentivorans DS-1|Rep: Short-chain dehydrogenase/reductase SDR - Parvibaculum lavamentivorans DS-1 Length = 287 Score = 85.8 bits (203), Expect = 1e-15 Identities = 56/188 (29%), Positives = 98/188 (52%), Gaps = 6/188 (3%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 L GKVA+ITG SGIG + LK+GAKV D+ +GE + +L +N +CR Sbjct: 4 LDGKVAIITGGTSGIGRGTVDLFLKEGAKVVAADLQDHKGEAMERELG-----ENFSYCR 58 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF--MNDRLWELEV---DVNLNGVIRGTLL 410 +V + + TV++F ++DI+ NNAG+ + L E+++ D + +++G +L Sbjct: 59 ANVAHEDEVKNLVDHTVKKFGKLDILFNNAGYGGVGGELQEIDMNGFDETVGVLLKGVVL 118 Query: 411 AYRF-MGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTGV 587 Y++ + + + G I++TAS A + +Y+A A+ +R + + V Sbjct: 119 GYKYAVPHMKAQKSGSIISTASVAGLQAGYGPLVYSACKAAVHHFSRCAALELAPHF--V 176 Query: 588 RCLVVCPG 611 R +CPG Sbjct: 177 RSNAICPG 184 >UniRef50_A4Z1Y9 Cluster: Putative short-chain dehydrogenases/reductase; n=1; Bradyrhizobium sp. ORS278|Rep: Putative short-chain dehydrogenases/reductase - Bradyrhizobium sp. (strain ORS278) Length = 305 Score = 85.8 bits (203), Expect = 1e-15 Identities = 66/195 (33%), Positives = 91/195 (46%), Gaps = 8/195 (4%) Frame = +3 Query: 72 GKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCRLD 251 GK L+TGA SGIG A + +QGA V C G +V ++ ++ GR F R D Sbjct: 53 GKTVLVTGATSGIGRAAAIAFARQGAAVVFCGRREALGREVEAEIKAEGGRAR--FIRAD 110 Query: 252 VTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDR-LWELE-------VDVNLNGVIRGTL 407 V + + V + F +DI +NNAG ++ L EL+ VD NL GV Sbjct: 111 VRVEAEMRDLVVQAIATFGGLDIALNNAGITIEKPLHELDAADWADVVDTNLRGVFFAMK 170 Query: 408 LAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTGV 587 M RG GG I+ T+S+ R YTAT +VG+ R+ Y N + Sbjct: 171 YEIAEM-LPRG--GGTILVTSSSVVHRTGPRRSAYTATKAGLVGMVRSAALDYADN--NI 225 Query: 588 RCLVVCPGLTDSGLV 632 R + PG TD+ LV Sbjct: 226 RINAILPGTTDTALV 240 >UniRef50_A3I4P3 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Bacillus sp. B14905|Rep: Short-chain dehydrogenase/reductase SDR - Bacillus sp. B14905 Length = 260 Score = 85.8 bits (203), Expect = 1e-15 Identities = 71/234 (30%), Positives = 109/234 (46%), Gaps = 8/234 (3%) Frame = +3 Query: 54 INMDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNV 233 + + LKGKVA+ITG++ GIG + +L+K+GA+V LC E+ QV +V Sbjct: 1 MELGLKGKVAIITGSSKGIGYYTAMQLVKEGAQVVLC-ARGEKQLQVAAGCIKNETGVDV 59 Query: 234 LFCRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAG--------FMNDRLWELEVDVNLNG 389 L D+T + TVE F +DI+INNAG ++ LW+ ++D+ + G Sbjct: 60 LIVPTDITKEKDCKNLIERTVEHFGHVDILINNAGTASANPFETVSSELWQADLDLKVFG 119 Query: 390 VIRGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYH 569 I + A +M R GG IVN + P S+ T + A + LT+A Sbjct: 120 AIHCSKYAAPYM---RKAGGGAIVNVTAVMAKTPPASSLPTTVSRAAGLALTKAMSKD-- 174 Query: 570 VNVTGVRCLVVCPGLTDSGLVXDLDKQLMSSKYETAWLEDITDSKCRALITLGK 731 + +R VC GL S ++K+ +W ED + K I LG+ Sbjct: 175 LGKDNIRVNSVCIGLIRS---DQIEKKWKKEDPSLSW-EDYS-RKVGQAIPLGR 223 >UniRef50_A1UAJ6 Cluster: Acetoin reductases; n=18; Bacteria|Rep: Acetoin reductases - Mycobacterium sp. (strain KMS) Length = 285 Score = 85.8 bits (203), Expect = 1e-15 Identities = 73/241 (30%), Positives = 106/241 (43%), Gaps = 12/241 (4%) Frame = +3 Query: 48 SSINMDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRK 227 + I L GKVAL+TGA GIG + EL +QGA ++L D+ SE G S+ G K Sbjct: 18 TQIPAPLSGKVALVTGAGRGIGRGIAVELARQGADIALVDV-SEAGLPDAAAEISEIGSK 76 Query: 228 NVLFCRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF----------MND--RLWELEV 371 F DV D A D+++NNAG D RLW + V Sbjct: 77 TTTFV-ADVRDRDAVFAAVDHAAAALGGFDVMVNNAGIALVGPIAEVTAEDLARLWAINV 135 Query: 372 DVNLNGVIRGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRA 551 D L G I+ ++ +G G+ I+N +S A Y+AT +A+ LT+A Sbjct: 136 DGVLWG-IQAAAAKFKELGNHAEGKVSKIINASSIAGHEGFAMLGPYSATKFAVRALTQA 194 Query: 552 YGDQYHVNVTGVRCLVVCPGLTDSGLVXDLDKQLMSSKYETAWLEDITDSKCRALITLGK 731 +Y + G+ CPG+ + + ++DK+ T E T K I LG+ Sbjct: 195 AAKEYAAD--GITVNAYCPGVVGTDMWVEIDKRFAEL---TGAAEGETFEKFSETIALGR 249 Query: 732 P 734 P Sbjct: 250 P 250 >UniRef50_A0QIV9 Cluster: Short chain dehydrogenase; n=5; root|Rep: Short chain dehydrogenase - Mycobacterium avium (strain 104) Length = 594 Score = 85.8 bits (203), Expect = 1e-15 Identities = 62/198 (31%), Positives = 98/198 (49%), Gaps = 9/198 (4%) Frame = +3 Query: 63 DLKGKVALITGAASGIGLAYSEELLKQGA-KVSLCDIDSERGEQVTEKLASKYGRKNVLF 239 +++G++AL+TGA +GIG A + EL +QGA KV + D D +Q + A + Sbjct: 322 EVRGRLALVTGAGAGIGRATAVELARQGARKVVIVDRDRAAADQTAD--AVRAAGAGAAV 379 Query: 240 CRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF-MNDRL-------WELEVDVNLNGVI 395 ++DV+D + E +DI++NNAG M R W+ + VN+ GVI Sbjct: 380 YQVDVSDEAAMNDLAAQVRNEHGVVDILVNNAGIGMAGRFLETSPANWDAIMGVNVRGVI 439 Query: 396 RGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVN 575 G+ A+ +R GQGG I+N AS A P S Y T A++ L+ + + Sbjct: 440 WGS-RAFGAQMVER-GQGGTIINVASAAAYLPSKSMVAYGTTKAAVLALSESLRADFADE 497 Query: 576 VTGVRCLVVCPGLTDSGL 629 G+ VCPG ++ + Sbjct: 498 --GITVTAVCPGFVNTNI 513 >UniRef50_Q2U0U8 Cluster: Dehydrogenases with different specificities; n=2; Pezizomycotina|Rep: Dehydrogenases with different specificities - Aspergillus oryzae Length = 271 Score = 85.8 bits (203), Expect = 1e-15 Identities = 74/233 (31%), Positives = 108/233 (46%), Gaps = 27/233 (11%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAK-VSLCDIDSERGEQVTEKLASKYGRKNVL 236 MD+ G +ALITGAASGIG A + + GA ++L D+D E V ++ S+ + Sbjct: 1 MDVPG-IALITGAASGIGRACAHTFARDGASGIALLDLDKTALETVQAEINSQSSQDKTA 59 Query: 237 FCRLD-----VTDYPQFEEAFVMTVEEFNRIDIVINNAG----------FMNDRLWELEV 371 CR++ VTD + +E + F+R+D V+N AG F W+ + Sbjct: 60 RCRVEIYPVNVTDENRVDEVINSAAQTFSRLDYVVNAAGIAMKHQGGAAFAETSDWQRIL 119 Query: 372 DVNLNGVIRGTLLAYRFMGKD---------RGGQGGVIVNTASTAFARPQVSTPIYTATN 524 DVNL G A R M R Q G IVN +S + YTAT Sbjct: 120 DVNLTGTFFVLRAAARIMLSQEPIRSSIDGRPLQRGSIVNFSSIQGVAGIPLSTAYTATK 179 Query: 525 YAIVGLTRAYGDQYHVNVTGVRCLVVCPGLTDSGLV--XDLDKQLMSSKYETA 677 +A++GLTR + Y + G+R +CPG T++ + L Q M + TA Sbjct: 180 HAVIGLTRTASEDYAKD--GLRINAICPGYTETPMTTKSPLVLQAMQERVATA 230 >UniRef50_A1CC09 Cluster: Short chain dehydrogenase/reductase family oxidoreductase, putative; n=3; Aspergillus|Rep: Short chain dehydrogenase/reductase family oxidoreductase, putative - Aspergillus clavatus Length = 261 Score = 85.8 bits (203), Expect = 1e-15 Identities = 70/208 (33%), Positives = 100/208 (48%), Gaps = 17/208 (8%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAK-VSLCDIDSERGEQVTEKLASKYGRKNVLFC 242 +KG A ITGAASGIG A + L K G ++L D + E +V +L S+Y ++ Sbjct: 4 VKG-TAFITGAASGIGRATAHTLAKNGITGLALFDTNHELLLEVHRELLSQYPEVDITIA 62 Query: 243 RLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRL---------WELEVDVNLNG-- 389 LDV D +A E F RIDI +N AG W+ +DVN G Sbjct: 63 ELDVRDETSVNQAIDSAAERFGRIDIGVNAAGISGAATRSHELALSDWQKVIDVNQKGLW 122 Query: 390 VIRGTLLAYRFMGKDRG-GQG-GVIVNTAST-AFARP--QVSTPIYTATNYAIVGLTRAY 554 + + + + RG +G GVIVN A+ A P + S YTA+ +A+VG+TR Sbjct: 123 LCQRAFIRQMLKQEPRGVREGRGVIVNVAAKFGVAAPPREFSVVAYTASKHAVVGITRVD 182 Query: 555 GDQYHVNVTGVRCLVVCPGLTDSGLVXD 638 Y + G+R VCPG D+ + + Sbjct: 183 SKAYAKD--GIRINAVCPGYVDTPMTHE 208 >UniRef50_P66781 Cluster: Uncharacterized oxidoreductase Rv1350/MT1393; n=19; Actinomycetales|Rep: Uncharacterized oxidoreductase Rv1350/MT1393 - Mycobacterium tuberculosis Length = 247 Score = 85.8 bits (203), Expect = 1e-15 Identities = 62/208 (29%), Positives = 98/208 (47%), Gaps = 8/208 (3%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 L + A+ITG A G+GLA + + +GA+V L D++ E E ++L G L R Sbjct: 5 LNARTAVITGGAQGLGLAIGQRFVAEGARVVLGDVNLEATEVAAKRLG---GDDVALAVR 61 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF--------MNDRLWELEVDVNLNGVIRG 401 DVT + VE F +D+++NNAG M + ++ + V+L G G Sbjct: 62 CDVTQADDVDILIRTAVERFGGLDVMVNNAGITRDATMRTMTEEQFDQVIAVHLKGTWNG 121 Query: 402 TLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVT 581 T LA M R + G IVN +S + V Y+A IVG+T+A + + Sbjct: 122 TRLAAAIM---RERKRGAIVNMSSVSGKVGMVGQTNYSAAKAGIVGMTKAAAKE--LAHL 176 Query: 582 GVRCLVVCPGLTDSGLVXDLDKQLMSSK 665 G+R + PGL S + + +++ K Sbjct: 177 GIRVNAIAPGLIRSAMTEAMPQRIWDQK 204 >UniRef50_Q9LBG2 Cluster: Levodione reductase (EC 1.1.1.-) ((6R)-2,2,6-trimethyl-1,4- cyclohexanedione reductase); n=4; Bacteria|Rep: Levodione reductase (EC 1.1.1.-) ((6R)-2,2,6-trimethyl-1,4- cyclohexanedione reductase) - Leifsonia aquatica (Corynebacterium aquaticum) Length = 267 Score = 85.8 bits (203), Expect = 1e-15 Identities = 67/202 (33%), Positives = 94/202 (46%), Gaps = 9/202 (4%) Frame = +3 Query: 75 KVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCRLDV 254 +V LITG SG+G A + L +GAK+SL D+ SE E + VL DV Sbjct: 14 RVVLITGGGSGLGRATAVRLAAEGAKLSLVDVSSEGLEASKAAVLETAPDAEVLTTVADV 73 Query: 255 TDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDR---------LWELEVDVNLNGVIRGTL 407 +D Q E T E F RID NNAG + ++ V +NL GV G Sbjct: 74 SDEAQVEAYVTATTERFGRIDGFFNNAGIEGKQNPTESFTAAEFDKVVSINLRGVFLGLE 133 Query: 408 LAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTGV 587 + M +++G G++VNTAS R + Y A + +VGLTR +Y G+ Sbjct: 134 KVLKIM-REQG--SGMVVNTASVGGIRGIGNQSGYAAAKHGVVGLTRNSAVEY--GRYGI 188 Query: 588 RCLVVCPGLTDSGLVXDLDKQL 653 R + PG + +V + KQL Sbjct: 189 RINAIAPGAIWTPMVENSMKQL 210 >UniRef50_O67610 Cluster: 3-oxoacyl-[acyl-carrier-protein] reductase; n=9; Bacteria|Rep: 3-oxoacyl-[acyl-carrier-protein] reductase - Aquifex aeolicus Length = 248 Score = 85.8 bits (203), Expect = 1e-15 Identities = 63/214 (29%), Positives = 103/214 (48%), Gaps = 8/214 (3%) Frame = +3 Query: 54 INMDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNV 233 + + L+GKV+L+TG+ GIG A +E+L G+ V + ER + V E++A+KYG K Sbjct: 1 MEIKLQGKVSLVTGSTRGIGRAIAEKLASAGSTVIITGTSGERAKAVAEEIANKYGVK-A 59 Query: 234 LFCRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRL--------WELEVDVNLNG 389 +++ +AF + IDI++NNAG D+L WE + VNL G Sbjct: 60 HGVEMNLLSEESINKAFEEIYNLVDGIDILVNNAGITRDKLFLRMSLLDWEEVLKVNLTG 119 Query: 390 VIRGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYH 569 T + R M K R G+ IVN +S V Y+ T ++G T++ + Sbjct: 120 TFLVTQNSLRKMIKQRWGR---IVNISSVVGFTGNVGQVNYSTTKAGLIGFTKSLAKE-- 174 Query: 570 VNVTGVRCLVVCPGLTDSGLVXDLDKQLMSSKYE 671 + V V PG ++ + L +++ KY+ Sbjct: 175 LAPRNVLVNAVAPGFIETDMTAVLSEEI-KQKYK 207 >UniRef50_Q8KKW9 Cluster: Putative oxidoreductase protein; n=1; Rhizobium etli CFN 42|Rep: Putative oxidoreductase protein - Rhizobium etli (strain CFN 42 / ATCC 51251) Length = 315 Score = 85.4 bits (202), Expect = 1e-15 Identities = 58/195 (29%), Positives = 95/195 (48%), Gaps = 8/195 (4%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 LK KVA++TGA+SGIG A + L ++GA+V L + ER Q+ E + G + + Sbjct: 4 LKNKVAIVTGASSGIGAATARGLAEKGARVVLAGRNEERLSQIVEDITGSGGIAS--YKV 61 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFM-----NDRL---WELEVDVNLNGVIRG 401 D TD+ + + +DI++NNAG M D W +D NL G + Sbjct: 62 ADATDFESTKALVAFATTTYGPVDILVNNAGLMLFSYWKDAAVGDWNKMIDTNLRGYLHA 121 Query: 402 TLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVT 581 M + R G+ I+N +S A + +Y AT + I G+T + + V + Sbjct: 122 IAAVLPSMLERRSGR---ILNMSSIAGVHVGEAAGVYGATKFFIRGITESLRKEVGVG-S 177 Query: 582 GVRCLVVCPGLTDSG 626 G++ ++ PG+ D+G Sbjct: 178 GIQVSMISPGVIDTG 192 >UniRef50_Q82FK0 Cluster: Putative dehydrogenase; n=2; Streptomyces|Rep: Putative dehydrogenase - Streptomyces avermitilis Length = 584 Score = 85.4 bits (202), Expect = 1e-15 Identities = 60/194 (30%), Positives = 97/194 (50%), Gaps = 8/194 (4%) Frame = +3 Query: 72 GKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCRLD 251 G++ L+TGA SGIG A + + GA+V D ++E G T +++ G + +D Sbjct: 316 GQLVLVTGAGSGIGRATAYAFAEAGARVVAVDRNAE-GAARTAEMSRLIGAPDAWAETVD 374 Query: 252 VTDYPQFEEAFVMTVEEFNRIDIVINNAG------FMNDRL--WELEVDVNLNGVIRGTL 407 V+D E+ E+ +D+++NNAG F + W +DVNL GVI G Sbjct: 375 VSDEQAMEKLAEKVATEYGVVDVLVNNAGIGLSGSFFDTTAEDWRKVLDVNLWGVIHGCR 434 Query: 408 LAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTGV 587 L + M + GQGG IVNTAS A +P + P Y+ + A++ L+ + + G+ Sbjct: 435 LFGKQMAER--GQGGHIVNTASAAAYQPSKALPAYSTSKAAVLMLSECL--RAELAGQGI 490 Query: 588 RCLVVCPGLTDSGL 629 +CPG + + Sbjct: 491 GVSAICPGFVHTNI 504 >UniRef50_Q1AU84 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 249 Score = 85.4 bits (202), Expect = 1e-15 Identities = 68/199 (34%), Positives = 103/199 (51%), Gaps = 10/199 (5%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 L+GKVA+ITGA SGIG A + + ++GA+V ++D GE V ++ S G +F R Sbjct: 2 LEGKVAVITGAGSGIGRATALKFAREGARVVAAELDERGGEGVVREVRSLGG--EAVFVR 59 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF--------MNDRLWELEVDVNLNGVIRG 401 DV+++ Q E+A V E+ +D++ NNAG ++ V VN GV G Sbjct: 60 TDVSEFAQVEDAVERAVGEYGTLDVMFNNAGIGHYAPLLEHEPEHYDRVVRVNQYGVYYG 119 Query: 402 TLLAYRFMGKDRGGQGGVIVNTAST-AF-ARPQVSTPIYTATNYAIVGLTRAYGDQYHVN 575 L A R M + G+I+NTAS AF A P V Y A A+ +T+A + Sbjct: 120 ILAAGRKMVALK--NPGLIINTASVYAFLASPGVIG--YHAAKGAVKMMTQAAA--LELA 173 Query: 576 VTGVRCLVVCPGLTDSGLV 632 G+R + + PG D+ ++ Sbjct: 174 PHGIRVVAIAPGGVDTPII 192 >UniRef50_A6VY27 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Marinomonas sp. MWYL1 Length = 252 Score = 85.4 bits (202), Expect = 1e-15 Identities = 66/211 (31%), Positives = 102/211 (48%), Gaps = 10/211 (4%) Frame = +3 Query: 54 INMDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNV 233 IN L K A++TG ASGIGLA E L GA V++ D+ E E+ + + SKY K + Sbjct: 2 INYQLDNKKAMVTGGASGIGLACVELLAYSGADVAIWDLHEEALEKAKQSI-SKYNVKCI 60 Query: 234 LFCRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF---------MNDRLWELEVDVNLN 386 ++DV+D + A T+++ +DI +NNAG W +DVN N Sbjct: 61 TI-KVDVSDPESVKAAMAETLKQLGSLDIAVNNAGIGGPACKSGDYTTEDWLKVIDVNFN 119 Query: 387 GVIRGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQY 566 GV A M K+ G I+N AS S+P Y + + +VG+++A ++ Sbjct: 120 GVFYCQREAIAAMRKNGSGS---IINMASILGQVAFPSSPAYVSAKHGVVGMSKASAVEH 176 Query: 567 HVNVTGVRCLVVCPGLTDSGLVXD-LDKQLM 656 + +R V PG + LV + LD + + Sbjct: 177 AED--NIRVNAVGPGFIHTPLVDEHLDAETL 205 >UniRef50_A4TAB8 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Mycobacterium|Rep: Short-chain dehydrogenase/reductase SDR - Mycobacterium gilvum PYR-GCK Length = 285 Score = 85.4 bits (202), Expect = 1e-15 Identities = 68/197 (34%), Positives = 93/197 (47%), Gaps = 8/197 (4%) Frame = +3 Query: 48 SSINMDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRK 227 S+ L GKVA +TG ASGIG A +L G +V + D E++ +L + Sbjct: 3 STDTAQLSGKVAFVTGGASGIGAALVAKLATAGTEVWIADRQIAPAEELAAQLRATGAVA 62 Query: 228 NVLFCRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF----MNDRL----WELEVDVNL 383 + + LDV D F A V+ R+D + NNAG D L W +DVNL Sbjct: 63 HAV--ELDVRDPAAFAHAVHTAVDTSGRLDYLFNNAGIGIGGEVDTLTLDDWTDIIDVNL 120 Query: 384 NGVIRGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQ 563 GVI G AY M + G IVNTAS A + Y+AT +A+V L++ + Sbjct: 121 KGVIHGVHAAYPQMIRQGSGH---IVNTASMAGLITTSAQGGYSATKHAVVALSKTM--R 175 Query: 564 YHVNVTGVRCLVVCPGL 614 GVR V+CPG+ Sbjct: 176 VEAATHGVRVSVLCPGV 192 >UniRef50_A3YE37 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Marinomonas sp. MED121|Rep: Short-chain dehydrogenase/reductase SDR - Marinomonas sp. MED121 Length = 255 Score = 85.4 bits (202), Expect = 1e-15 Identities = 61/201 (30%), Positives = 102/201 (50%), Gaps = 10/201 (4%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDID-SERGEQVTEKLASKYGRKNVL 236 M+ K +V LITGA+ G+G +++ +QGAK++LCD++ + + TE + Y V Sbjct: 2 MNFKDQVVLITGASGGLGKEAAKQFAQQGAKLALCDLNVAALNDLGTELIEQGY---EVF 58 Query: 237 FCRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF---------MNDRLWELEVDVNLNG 389 DV++ + + T F R+D+ INNAG M+ R +E +D+N+ G Sbjct: 59 SQPCDVSNEQEVQSFIDNTAAHFGRLDVAINNAGIDPKHSTLADMDTRDFERVMDINVKG 118 Query: 390 VIRGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYH 569 V + Y+ + G GG I N +S A Y A+ +A++GLT++ +Y Sbjct: 119 VY--LCMKYQIPHMIKQG-GGAICNMSSVAGISGAPFMSAYAASKHAVIGLTKSVAHEY- 174 Query: 570 VNVTGVRCLVVCPGLTDSGLV 632 G+R VCP +T + +V Sbjct: 175 -GRAGIRVNSVCPYITMTDMV 194 >UniRef50_A1WKP5 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Verminephrobacter eiseniae EF01-2|Rep: Short-chain dehydrogenase/reductase SDR - Verminephrobacter eiseniae (strain EF01-2) Length = 265 Score = 85.4 bits (202), Expect = 1e-15 Identities = 64/205 (31%), Positives = 97/205 (47%), Gaps = 8/205 (3%) Frame = +3 Query: 63 DLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFC 242 ++ GKVALITGA SGIG A + +GA++ +CD+D E G Q T + + G + LF Sbjct: 12 EVAGKVALITGAGSGIGRATALLFATEGAQIVVCDLDPE-GGQATVRAIEQAGAQ-ALFV 69 Query: 243 RLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF--------MNDRLWELEVDVNLNGVIR 398 + DV A T+ F R+D++ NNAG ++ W+ + VN+ + Sbjct: 70 QADVAQAADCARAVQQTLRHFARLDVLFNNAGITCRANVVDTSEADWDAVMAVNVKSIFL 129 Query: 399 GTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNV 578 + A M + GG I+N S Y A A+V +TRA + Sbjct: 130 MSRQAVPVMAEQGGGS---IINAGSGWGLVGGRDAVSYCAAKGAVVNMTRAMALDH--GP 184 Query: 579 TGVRCLVVCPGLTDSGLVXDLDKQL 653 +R VCPG TD+ ++ D +QL Sbjct: 185 QRIRVNSVCPGDTDTAMLRDEARQL 209 >UniRef50_A0R6X9 Cluster: Cyclopentanol dehydrogenase; n=2; Bacteria|Rep: Cyclopentanol dehydrogenase - Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) Length = 250 Score = 85.4 bits (202), Expect = 1e-15 Identities = 65/194 (33%), Positives = 96/194 (49%), Gaps = 9/194 (4%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLF 239 M L GK+ALITGAA+G+G A +E +QGA V + D+D E G QV +++ + G + F Sbjct: 1 MRLAGKIALITGAANGMGCATAETFSRQGATVVIADVDDEDGLQVAKQIGTSGGTAH--F 58 Query: 240 CRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAG--------FMNDRLWELEVDVNLNGVI 395 LDVTD + A + + R+DI++NNAG + ++ + VN GV Sbjct: 59 VHLDVTDETAWACAVEDVLGRYERLDILVNNAGISGTFDPDLTSTAFFDRLIAVNARGVF 118 Query: 396 RGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPI-YTATNYAIVGLTRAYGDQYHV 572 G M K G GG IVN +S + Q+ + Y A+ A+ +T H Sbjct: 119 LGIKHGAAAM-KHTG--GGSIVNLSSISAHIGQLGVHLGYGASKAAVKAMTTTAA--VHY 173 Query: 573 NVTGVRCLVVCPGL 614 G+R V PG+ Sbjct: 174 AADGIRVNAVAPGM 187 >UniRef50_Q49WS9 Cluster: Uncharacterized oxidoreductase SSP1627; n=13; Bacteria|Rep: Uncharacterized oxidoreductase SSP1627 - Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 /DSM 20229) Length = 246 Score = 85.4 bits (202), Expect = 1e-15 Identities = 64/227 (28%), Positives = 104/227 (45%), Gaps = 9/227 (3%) Frame = +3 Query: 63 DLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFC 242 ++K KV +ITGA+SGIG L + GAK+ L + R +++ EK+ K G +V Sbjct: 3 NVKDKVVVITGASSGIGEETVNLLSENGAKLVL---GARRLDRL-EKIQQKVGHDSVSIK 58 Query: 243 RLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRL--------WELEVDVNLNGVIR 398 + DVT + +F RID++INNAG M W +DVN+ GV+ Sbjct: 59 KTDVTKPDEVNALIETAYNDFGRIDVLINNAGLMPQSFLEKNKQDEWNQMIDVNIKGVLY 118 Query: 399 GTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNV 578 G +M K + G I+N AS A + +Y T YA+ +T + + Sbjct: 119 GIGAVLPYMRKQKSGH---IINLASVAGHVVFPGSAVYCGTKYAVRAITEGLRQEEAIVG 175 Query: 579 TGVRCLVVCPGLTDSGLVXDLDKQLMSSKYETAWLEDI-TDSKCRAL 716 + +R ++ PG + L + + M + + I D+ RA+ Sbjct: 176 SNIRTTILSPGAVSTELTDHISDKDMKQDIDELYKNAIKPDAIARAI 222 >UniRef50_Q5KRX7 Cluster: Putative oxidoreductase; n=2; Corynebacterium glutamicum|Rep: Putative oxidoreductase - Corynebacterium glutamicum (Brevibacterium flavum) Length = 279 Score = 85.0 bits (201), Expect = 2e-15 Identities = 57/204 (27%), Positives = 102/204 (50%), Gaps = 8/204 (3%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 ++GKVA ITGAASG+G +++ L GAKV + D++ E G+++ +++ G + + Sbjct: 35 VEGKVAFITGAASGMGASHARVLAAHGAKVVITDLNDELGQELVKEI----GEEKAHYVH 90 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRL--------WELEVDVNLNGVIRG 401 L+VT + ++E A +E F +ID +INNAG + W+ + ++LNG G Sbjct: 91 LNVTSFEEWEVAVQKALERFGKIDTLINNAGIFSSGSVEDATAADWDKTIAIDLNGTFYG 150 Query: 402 TLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVT 581 A + ++ I+N +S A + Y+A + + GLT+ + Sbjct: 151 MKAALPALKENPTAS---IINISSIAGVTGFKNRAAYSAAKWGVQGLTKT--SAMDLGKY 205 Query: 582 GVRCLVVCPGLTDSGLVXDLDKQL 653 +R V PG ++ L +L + L Sbjct: 206 NIRVNSVHPGSVETPLTANLKRGL 229 >UniRef50_Q0C3R5 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family; n=1; Hyphomonas neptunium ATCC 15444|Rep: Oxidoreductase, short chain dehydrogenase/reductase family - Hyphomonas neptunium (strain ATCC 15444) Length = 282 Score = 85.0 bits (201), Expect = 2e-15 Identities = 60/197 (30%), Positives = 95/197 (48%), Gaps = 8/197 (4%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 L+GK A +TGAASGIGL + L + G KV LCDI+ ++ L + + Sbjct: 4 LEGKTAFVTGAASGIGLGIATALAQAGVKVMLCDIEKAALDKAVATLRETNADVDGVVAD 63 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF--------MNDRLWELEVDVNLNGVIRG 401 + + D + A T+ F ++ I++NNAG ND W V VNL V+ G Sbjct: 64 VSLKD--NLQRAADETIARFGKVHILVNNAGVGGGGDYGTWNDAGWNWVVGVNLMSVVWG 121 Query: 402 TLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVT 581 + + + G+GG IV+TAS A ++ P Y T + +V L+ + + Sbjct: 122 IEIFGPLI--EAHGEGGQIVSTASIA-GMVALTNPAYDVTKFGVVALSEDLRPK--LAAR 176 Query: 582 GVRCLVVCPGLTDSGLV 632 G+ V+CPG+ + +V Sbjct: 177 GIGVSVLCPGVIRTNIV 193 >UniRef50_Q56318 Cluster: Uncharacterized oxidoreductase TM_0019; n=11; cellular organisms|Rep: Uncharacterized oxidoreductase TM_0019 - Thermotoga maritima Length = 256 Score = 85.0 bits (201), Expect = 2e-15 Identities = 60/185 (32%), Positives = 92/185 (49%), Gaps = 11/185 (5%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 L+GKVA++TG GIG A ++ + G KV + +ID E G + E L + +V F + Sbjct: 2 LEGKVAVVTGGGQGIGAAIAQLFAENGMKVVIAEIDEEAGVEREEMLRER--GLDVTFVK 59 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRL--------WELEVDVNLNGVIRG 401 DV D + TVE + +D+++NNA M+ + WE + VNL G Sbjct: 60 TDVADENSVKNMVRKTVEIYGGVDVLVNNAAVMSVKSIFERPLEEWERVIRVNLTGPYIC 119 Query: 402 TLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYG---DQYHV 572 + M K RG GGVI+N AST + + T Y+A+ +V LT + +YH+ Sbjct: 120 SRYCAEEMIK-RG--GGVIINIASTRAFQSEPDTEPYSASKGGLVALTHSLAVSLSRYHI 176 Query: 573 NVTGV 587 V + Sbjct: 177 RVVSI 181 >UniRef50_Q59787 Cluster: Sorbitol dehydrogenase; n=60; Bacteria|Rep: Sorbitol dehydrogenase - Rhodobacter sphaeroides (Rhodopseudomonas sphaeroides) Length = 256 Score = 85.0 bits (201), Expect = 2e-15 Identities = 59/193 (30%), Positives = 98/193 (50%), Gaps = 6/193 (3%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLF 239 M L GK ALITG+A GIG A++E +++GA+V++ DI+ E ++ Sbjct: 1 MRLDGKTALITGSARGIGRAFAEAYVREGARVAIADINLEAARATAAEIGPA-----ACA 55 Query: 240 CRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMN-DRLWEL--EVDVNLNGV-IRGTL 407 LDVTD + ++ + IDI++NNA + + E+ E L + + GTL Sbjct: 56 IALDVTDQASIDRCVAELLDRWGSIDILVNNAALFDLAPIVEITRESYDRLFAINVSGTL 115 Query: 408 LAYRFMGKD--RGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVT 581 + + + GG+GG I+N AS A R + +Y AT A++ LT++ G ++ Sbjct: 116 FMMQAVARAMIAGGRGGKIINMASQAGRRGEALVGVYCATKAAVISLTQSAG--LNLIRH 173 Query: 582 GVRCLVVCPGLTD 620 G+ + PG+ D Sbjct: 174 GINVNAIAPGVVD 186 >UniRef50_UPI000045C1E7 Cluster: COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); n=1; Nostoc punctiforme PCC 73102|Rep: COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - Nostoc punctiforme PCC 73102 Length = 247 Score = 84.6 bits (200), Expect = 2e-15 Identities = 63/176 (35%), Positives = 86/176 (48%), Gaps = 6/176 (3%) Frame = +3 Query: 57 NMDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVL 236 N + GKVA +TGAA+GIG A + ++GA V + D+ SE+G Q T +L G + VL Sbjct: 6 NGNYTGKVAFVTGAANGIGRATALAFAREGANVVVADV-SEQGNQETVRLIEDLGGR-VL 63 Query: 237 FCRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDR-----LWELEVDVNLNGVIRG 401 + DVT A T+E F R+D NNAG + L E E D +N +R Sbjct: 64 AVKCDVTRTEDVTAALSKTIETFGRLDFAFNNAGVEQKKAATAELEEAEWDRIVNTDLRS 123 Query: 402 TLLAYRFMGKDRGGQ-GGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQY 566 L + Q GG IVNT+S A YTA + ++GLT+A Y Sbjct: 124 VFLCLKHEIPLMLKQGGGAIVNTSSGAGVIGIKGGAAYTAAKHGVIGLTKAAALDY 179 >UniRef50_Q8YCL4 Cluster: 3-OXOACYL-(ACYL-CARRIER PROTEIN) REDUCTASE; n=6; Brucellaceae|Rep: 3-OXOACYL-(ACYL-CARRIER PROTEIN) REDUCTASE - Brucella melitensis Length = 249 Score = 84.6 bits (200), Expect = 2e-15 Identities = 64/194 (32%), Positives = 95/194 (48%), Gaps = 9/194 (4%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 L+ KVA+ITGA SG GL + +GA+V L D++ +R E ++S N + + Sbjct: 4 LQDKVAIITGAGSGFGLGMARRFAAEGARVVLADVNVKRVEDGLADISS-----NGISIQ 58 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF---------MNDRLWELEVDVNLNGVIR 398 DV+ E EEF RIDI++NNAGF +++ ++L V VN+ + Sbjct: 59 ADVSRKNDMERVARTAFEEFGRIDIMVNNAGFTHRNMPLTDVDEHNFDLIVAVNMKALYY 118 Query: 399 GTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNV 578 T L M + +G GGVI+NTAS P+ Y A+ +V T+A + Sbjct: 119 STQLVVPIM-EHQG--GGVIINTASATGLHPRKGLTWYCASKSWVVSATKAMALELAERN 175 Query: 579 TGVRCLVVCPGLTD 620 V CL CP +D Sbjct: 176 IRVNCL--CPAESD 187 >UniRef50_Q82GU5 Cluster: Putative dehydrogenase; n=1; Streptomyces avermitilis|Rep: Putative dehydrogenase - Streptomyces avermitilis Length = 258 Score = 84.6 bits (200), Expect = 2e-15 Identities = 63/195 (32%), Positives = 97/195 (49%), Gaps = 7/195 (3%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 L G+V LI+GAA G G + +++GAKV + D+ ++GE + +++ ++Y Sbjct: 4 LDGRVVLISGAARGQGEQEARLFVEEGAKVVVADVLDDQGEALAKEIGARY-------VH 56 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFM--ND----RLWELEVDVNLNGVIRGTL 407 LDV ++ A + + + ID ++NNAG + ND L E + V +N V G Sbjct: 57 LDVGREDDWQAAVTVAKDAYGHIDGLVNNAGILRFNDLVGTPLAEFQQIVQVNQV--GVF 114 Query: 408 LAYRFMGKD-RGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTG 584 L + + + GG IVNTAS A YTAT +AIVGLTR + Sbjct: 115 LGIKTVAPEIEAAGGGTIVNTASYAGLTGMAYVGAYTATKHAIVGLTRVAA--LELAAKK 172 Query: 585 VRCLVVCPGLTDSGL 629 +R VCPG D+ + Sbjct: 173 IRVNAVCPGAIDTAM 187 >UniRef50_Q1YP86 Cluster: Oxidoreductase; n=2; unclassified Gammaproteobacteria (miscellaneous)|Rep: Oxidoreductase - gamma proteobacterium HTCC2207 Length = 253 Score = 84.6 bits (200), Expect = 2e-15 Identities = 63/201 (31%), Positives = 98/201 (48%), Gaps = 6/201 (2%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLF 239 M L KV LITGA GIG A + + +GAKV L DI+++ +T+ L ++ G Sbjct: 1 MKLDQKVVLITGAGGGIGQAAVRKFVSEGAKVMLADINTD----ITQPLVNELGAYRCAC 56 Query: 240 CRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRLWELEVDV-NLNGV----IRGT 404 +DV + Q E TV+ F ID+ + NAG ++ DV NL+ V +RG Sbjct: 57 VAVDVAEADQVENMVRTTVDTFGSIDVFVANAGTEGKIGSIMDTDVSNLDKVLAVNVRGV 116 Query: 405 LLAYRF-MGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVT 581 L + M R G GG I+ T+S A + +T Y + +A++GL R Sbjct: 117 WLGLHYVMPVMRDGGGGSIIITSSGAGVQGSPNTAAYNTSKHAVIGLMRCAA--LESAQF 174 Query: 582 GVRCLVVCPGLTDSGLVXDLD 644 G+R V PG ++ ++ ++ Sbjct: 175 GIRVNTVNPGAVETRMMESIE 195 >UniRef50_Q0K3J3 Cluster: Short chain dehydrogenase; n=2; Cupriavidus necator|Rep: Short chain dehydrogenase - Ralstonia eutropha (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)(Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier337)) Length = 271 Score = 84.6 bits (200), Expect = 2e-15 Identities = 68/196 (34%), Positives = 93/196 (47%), Gaps = 6/196 (3%) Frame = +3 Query: 75 KVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCRLDV 254 + A+ITGAASGIG A ++ L QG ++L DID+ E V E LA + NV+ DV Sbjct: 10 QAAVITGAASGIGRALAQALAAQGYALALADIDAGALEAVREALAGQ--GANVIAVPTDV 67 Query: 255 TDYPQFEEAFVMTVEEFNRIDIVINNAG-FMNDRLWELEVDVNLNGVIR----GTLLAYR 419 D Q E + R+D+++NNAG + R WEL +V + V+R L A R Sbjct: 68 CDARQIEHLCEESFLRLGRVDLLVNNAGVLVTGRCWELPPEV-FDHVMRVNLWSVLHALR 126 Query: 420 FMGKDRGGQG-GVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTGVRCL 596 QG G IVN AS A YT + A+V L+ + + Sbjct: 127 CFVPRMAAQGAGHIVNVASMAGLAVGPWLAPYTLSKQAVVALSEGLALELQAAGLPLGVS 186 Query: 597 VVCPGLTDSGLVXDLD 644 VVCPG +G+ LD Sbjct: 187 VVCPGPVATGIAAGLD 202 >UniRef50_Q62GY7 Cluster: Oxidoreductase, short-chain dehydrogenase/reductase family; n=36; Proteobacteria|Rep: Oxidoreductase, short-chain dehydrogenase/reductase family - Burkholderia mallei (Pseudomonas mallei) Length = 269 Score = 84.2 bits (199), Expect = 3e-15 Identities = 64/200 (32%), Positives = 94/200 (47%), Gaps = 9/200 (4%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 L GKVA++TGA GIG A + +++GA V++ ++D+ E+ + +A VL Sbjct: 14 LAGKVAIVTGAGRGIGAAIARAFVREGAAVAIAELDAALAEESADAIARDTAGARVLAVP 73 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF--------MNDRLWELEVDVNLNGVIRG 401 DV A T F +D+++NNAG + D W ++L+GV G Sbjct: 74 TDVARAESVAAALARTERAFGPLDVLVNNAGVNVFGDPLALTDEDWRRCFAIDLDGVWNG 133 Query: 402 TLLAYRFMGKDRGGQGGVIVNTAST-AFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNV 578 A M +RG G IVN AST AF P Y + ++GLTRA G +Y Sbjct: 134 CRAALPGM-VERG--RGSIVNIASTHAFKIIPGCFP-YPVAKHGVLGLTRALGIEYAPR- 188 Query: 579 TGVRCLVVCPGLTDSGLVXD 638 VR + PG ++ L D Sbjct: 189 -NVRVNAIAPGYIETQLTHD 207 >UniRef50_Q0B254 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Burkholderia ambifaria AMMD|Rep: Short-chain dehydrogenase/reductase SDR - Burkholderia cepacia (strain ATCC 53795 / AMMD) Length = 252 Score = 84.2 bits (199), Expect = 3e-15 Identities = 57/195 (29%), Positives = 88/195 (45%), Gaps = 9/195 (4%) Frame = +3 Query: 75 KVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCRLDV 254 KVAL+TGA SGIG A + ++GAKV++ E G QV ++ G +F R DV Sbjct: 7 KVALVTGATSGIGKATAMLFAREGAKVAIAARREEEGRQVVREILDHGG--EAIFVRTDV 64 Query: 255 TDYPQFEEAFVMTVEEFNRIDIVINNAGF---------MNDRLWELEVDVNLNGVIRGTL 407 A TV F ++DI NNAG +++ W +DVNL G Sbjct: 65 AQAEDCAAAVARTVASFGKLDIAFNNAGITSFGRPVADTDEQAWSTVIDVNLTGTFLS-- 122 Query: 408 LAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTGV 587 + Y + G G +I +++ A Y A+ + ++GLTRA +Y + Sbjct: 123 MKYEIPEILKAGGGSIINMSSAYGLAGSAFGACSYHASKHGVIGLTRAAALEYAKE--KL 180 Query: 588 RCLVVCPGLTDSGLV 632 R +CP + ++ Sbjct: 181 RVNAICPAFVATDMI 195 >UniRef50_A0Z2D1 Cluster: Short-chain dehydrogenase/reductase (SDR) family protein; n=4; unclassified Gammaproteobacteria (miscellaneous)|Rep: Short-chain dehydrogenase/reductase (SDR) family protein - marine gamma proteobacterium HTCC2080 Length = 278 Score = 84.2 bits (199), Expect = 3e-15 Identities = 58/169 (34%), Positives = 82/169 (48%), Gaps = 9/169 (5%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 L+GKVA+ITGAASGIG A ++ +G + L DI SE G ++L +V F Sbjct: 5 LEGKVAVITGAASGIGAATAQRFKDEGCLLVLADIQSELGLDFAKQLGD-----HVYFEA 59 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDR---------LWELEVDVNLNGVIR 398 DV+ E + EF ++DI+ NNAG + + W D+ +NGV Sbjct: 60 CDVSIETDVERVVNRAILEFGKLDIMFNNAGIVGAKGPIDLTPADEWRATTDILINGVFY 119 Query: 399 GTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLT 545 G A M K R G I+N +S A ++ YT +A+VGLT Sbjct: 120 GVKHAAAIMKKQRSGS---IINMSSVAGVMGGLAPHAYTTAKHAVVGLT 165 >UniRef50_A0TW00 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Burkholderia cenocepacia MC0-3|Rep: Short-chain dehydrogenase/reductase SDR precursor - Burkholderia cenocepacia MC0-3 Length = 277 Score = 84.2 bits (199), Expect = 3e-15 Identities = 63/193 (32%), Positives = 97/193 (50%), Gaps = 10/193 (5%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 +KGK+A++TGAASGIG A + L +GA V + D++ E ++ +A G + + R Sbjct: 4 VKGKIAIVTGAASGIGAACAARLAHEGASVVVADLNLEGAQEQVRHIADSGG--HAVAAR 61 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMN-----DRLWE-LEV---DVNLNGVIR 398 +D+ D E F +T++ + +DI+ NNA + D E ++V D + +R Sbjct: 62 VDIGDECSIEALFDLTLKTWGGLDILHNNAAATSLSSTADAAIEAIDVAVWDDTMRINLR 121 Query: 399 GTLLA-YRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVN 575 GT+LA R + R GG I+NT+S A + Y I LTR QY Sbjct: 122 GTMLASRRALPLMRSRGGGSIINTSSGAAQAGALGYSAYGVCKAGIENLTRYIAAQY--G 179 Query: 576 VTGVRCLVVCPGL 614 G+RC + PGL Sbjct: 180 KEGIRCNAIAPGL 192 >UniRef50_Q6C6W8 Cluster: Similar to tr|Q9WYD3 Thermotoga maritima TM0297 Oxidoreductase; n=7; Ascomycota|Rep: Similar to tr|Q9WYD3 Thermotoga maritima TM0297 Oxidoreductase - Yarrowia lipolytica (Candida lipolytica) Length = 291 Score = 84.2 bits (199), Expect = 3e-15 Identities = 65/213 (30%), Positives = 102/213 (47%), Gaps = 12/213 (5%) Frame = +3 Query: 27 F*ARCFYSSINMDLKGKVALITGAASGIGLAYSEELLKQGAK-VSLCDIDSERGEQVTEK 203 F A+ F S +D GKVA++TG A G+G + +E L G K +++ D+ + G EK Sbjct: 32 FQAKNFLSKFRLD--GKVAIVTGGARGLGFSMAEGLCSVGLKGIAILDVQQDLGLDAIEK 89 Query: 204 LASKYGRKNVLFCRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAG---------FMNDRL 356 L YG F + DV D E V + +D+V+N+AG + D+ Sbjct: 90 LHKAYG-VQAQFYKADVRDEESVNEIIDRVVHDLGSVDVVVNSAGVADLVHAAEYPADKF 148 Query: 357 WELEVDVNLNGVIRGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTP--IYTATNYA 530 + +D+NLNG T A R M K G GG +V AS + + P Y A+ A Sbjct: 149 RRV-IDINLNGSFLVTQAAARHMIKQ--GTGGTVVFIASMSGSIVNWPQPQSAYNASKAA 205 Query: 531 IVGLTRAYGDQYHVNVTGVRCLVVCPGLTDSGL 629 + L+++ ++ V+ +RC + PG D+ L Sbjct: 206 VKHLSKSLAAEWAVH--NIRCNSISPGYMDTAL 236 >UniRef50_A3CUL1 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Methanoculleus marisnigri JR1|Rep: Short-chain dehydrogenase/reductase SDR - Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1) Length = 278 Score = 84.2 bits (199), Expect = 3e-15 Identities = 66/188 (35%), Positives = 90/188 (47%), Gaps = 9/188 (4%) Frame = +3 Query: 72 GKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCRLD 251 GKV L+TGA SGIG A SEELLK+GA V + E+ +L++ R L +D Sbjct: 9 GKVCLVTGANSGIGYAISEELLKRGAVVYMAGRSREKVAAAVARLSAYGDRARPLV--VD 66 Query: 252 VTDYPQFEEAFVMTVEEFNRIDIVINNAG------FMNDRL--WELEVDVNLNGVIRGTL 407 VT Q + T E R+D + NNAG F L W+ +D N+ V+ G Sbjct: 67 VTKQEQVRKGIEDTAAEAGRLDFLFNNAGVGGTIPFEAATLEDWKAIIDTNIWSVVYGVH 126 Query: 408 LAYRFMGKDRGGQG-GVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTG 584 A M K QG G +VNT+S A P +Y+ T Y + GLT + +Y G Sbjct: 127 AAVPIMLK----QGFGHVVNTSSIAGIVPPPFQALYSLTKYGVTGLTESL--KYEYADKG 180 Query: 585 VRCLVVCP 608 + +CP Sbjct: 181 LYFSTICP 188 >UniRef50_Q3IE74 Cluster: 2O-beta-hydroxysteroid dehydrogenase; n=2; Proteobacteria|Rep: 2O-beta-hydroxysteroid dehydrogenase - Pseudoalteromonas haloplanktis (strain TAC 125) Length = 262 Score = 83.8 bits (198), Expect = 4e-15 Identities = 64/194 (32%), Positives = 92/194 (47%), Gaps = 8/194 (4%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 L KVAL+TGAA GIG A + L+ GA V DI +E Q+ ++L K V Sbjct: 7 LTNKVALVTGAARGIGRAICQALVDSGATVIATDILTEELNQMAQELGDK-----VTPMT 61 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFM--------NDRLWELEVDVNLNGVIRG 401 DVTD Q++ T+E+ +IDI++NNAG + + + +D+N+ G G Sbjct: 62 HDVTDELQWQSIVSATLEKHQKIDILVNNAGILLFATLETTEPQQFRKLIDINITGTFLG 121 Query: 402 TLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVT 581 M K G IVN +S + P T Y A+ YA+ GLTR + Sbjct: 122 LHSVIPCMKK---AGSGAIVNISSASSILPNNGTGAYAASKYAVRGLTRTAA--LELGPF 176 Query: 582 GVRCLVVCPGLTDS 623 G+R V PG ++ Sbjct: 177 GIRVNSVHPGAVNT 190 >UniRef50_Q390G9 Cluster: Short-chain dehydrogenase/reductase SDR; n=33; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 / R18194)) Length = 254 Score = 83.8 bits (198), Expect = 4e-15 Identities = 70/221 (31%), Positives = 107/221 (48%), Gaps = 11/221 (4%) Frame = +3 Query: 63 DLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFC 242 DL GK+AL+TGA+ GIG ++ L +QGA V + + + V +++ + GR L C Sbjct: 7 DLTGKIALVTGASRGIGEEIAKLLAEQGAHVIVSSRKLDDCQAVADEIVAAGGRAEALAC 66 Query: 243 RLDVTDYPQFEEAFVMTVEEFNRIDIVINNA------GFMND---RLWELEVDVNLNGVI 395 + D F + R+DI++NNA G + D +E VDVN+ G Sbjct: 67 HVGRLD--DIAATFEHIRGKHGRLDILVNNAAANPYFGHILDTDLAAYEKTVDVNIRGYF 124 Query: 396 RGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVN 575 ++ A + M + GG IVNTAS +P IY+ T A+V +T+A+ + Sbjct: 125 FMSVEAGKLM---KANGGGAIVNTASVNALQPGDRQGIYSITKAAVVNMTKAFAKE--CG 179 Query: 576 VTGVRCLVVCPGLTDSGLVXDL--DKQLMSSKYETAWLEDI 692 G+R + PGLT + L DK + YET W+ I Sbjct: 180 PLGIRVNALLPGLTKTKFAGALFADKDI----YET-WMGKI 215 >UniRef50_Q0LUS2 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Caulobacter sp. K31|Rep: Short-chain dehydrogenase/reductase SDR - Caulobacter sp. K31 Length = 254 Score = 83.8 bits (198), Expect = 4e-15 Identities = 63/200 (31%), Positives = 99/200 (49%), Gaps = 6/200 (3%) Frame = +3 Query: 51 SINMDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKN 230 S+N LKGKVA+ITGAA G+G A + E + +GA V + D+ E GE V + ++ G+ Sbjct: 2 SVNDSLKGKVAIITGAAQGLGEAIAREFVARGAAVIITDVQREEGEAVAADILAQGGK-- 59 Query: 231 VLFCRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMN-DRLWELEVDV--NLNGV-IR 398 LF DV D ++ ++ F ++D+++NNAG + L E+ +++ + V +R Sbjct: 60 ALFIAHDVGDAEAWDVVVAKALDTFGKVDVLVNNAGLIQFAPLEEMPIEMFDRVTRVNVR 119 Query: 399 GTLLAYR-FMGKDRGGQGGVIVNTAS-TAFARPQVSTPIYTATNYAIVGLTRAYGDQYHV 572 G L + + + GG I+N +S Y + A+ LT+A Y V Sbjct: 120 GPWLGCKAILPALKAAGGGAIINMSSMNGMIAQNPGLSAYATSKGAVRMLTKAVAQDY-V 178 Query: 573 NVTGVRCLVVCPGLTDSGLV 632 GVR V PG S V Sbjct: 179 QY-GVRVNSVHPGTIASTFV 197 >UniRef50_A5V529 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Sphingomonas wittichii RW1|Rep: Short-chain dehydrogenase/reductase SDR - Sphingomonas wittichii RW1 Length = 255 Score = 83.8 bits (198), Expect = 4e-15 Identities = 62/197 (31%), Positives = 91/197 (46%), Gaps = 8/197 (4%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 L G+VAL+TG A GIG E L +GA V D+D + +A++ G + L+ R Sbjct: 4 LAGRVALVTGGARGIGRGIVERFLAEGATVMATDLDVD-----DAPVAAELGER-ALYHR 57 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF--------MNDRLWELEVDVNLNGVIRG 401 LDVT + A + R+DI++NNAG ++ W +D N V G Sbjct: 58 LDVTRADDWTAALDALRDRCGRVDILVNNAGTSRSGSIEDASEADWRFVMDTNALSVFLG 117 Query: 402 TLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVT 581 A R M GG IVN AS R + Y+A+ A++ LT + Sbjct: 118 CQAAVRAM----RATGGAIVNIASARGQRTGAAQCAYSASKAAVLSLTESVALHCGEQGL 173 Query: 582 GVRCLVVCPGLTDSGLV 632 +RC +CPG+ D+ L+ Sbjct: 174 PIRCNAICPGVIDTPLM 190 >UniRef50_A3XKE6 Cluster: Short-chain dehydrogenase/reductase SDR; n=5; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Leeuwenhoekiella blandensis MED217 Length = 257 Score = 83.8 bits (198), Expect = 4e-15 Identities = 50/170 (29%), Positives = 90/170 (52%), Gaps = 8/170 (4%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 +K KVA++TG ASG+G + ++ L ++GAK+ + DID E G++V +++ G +F + Sbjct: 4 VKNKVAIVTGGASGLGKSSAKLLAREGAKIVVSDIDEEGGKKVVQQIKEDGG--EAIFIK 61 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF-----MND---RLWELEVDVNLNGVIRG 401 DV +++ T+E + ++ I+ N+AG + D W+ +D+NLNG G Sbjct: 62 QDVAKEDEWKNVIETTLETYGKLHILANSAGIGLGGTVEDVTLEDWKNLIDINLNGTFLG 121 Query: 402 TLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRA 551 T Y G + +GG I+N +S + P Y A+ + T++ Sbjct: 122 T--KYGIKGMRKTDEGGSIINFSSIEGLIGDPNLPAYNASKGGVTIFTKS 169 >UniRef50_Q8U3B3 Cluster: 3-oxoacyl-[acyl-carrier protein] reductase; n=3; cellular organisms|Rep: 3-oxoacyl-[acyl-carrier protein] reductase - Pyrococcus furiosus Length = 260 Score = 83.8 bits (198), Expect = 4e-15 Identities = 63/186 (33%), Positives = 93/186 (50%), Gaps = 11/186 (5%) Frame = +3 Query: 63 DLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFC 242 +LK KVA++TG GIG A ++ + GAKV L +ID E G + E + + G +V F Sbjct: 5 NLKNKVAIVTGGGQGIGAAIAQLFAENGAKVVLAEIDEEAGLE-REAMLRERG-LDVTFI 62 Query: 243 RLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRL--------WELEVDVNLNGVIR 398 + DV D + TVE + +DI++NNA M+ + WE + VNL G Sbjct: 63 KTDVADEESVKNMVKKTVELYGGVDILVNNAAIMSVKSIFERTLEEWERVIRVNLTGPYI 122 Query: 399 GTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYG---DQYH 569 + A M K RG GGVI+N AST + T Y+A+ ++ LT + +Y Sbjct: 123 CSRYAAEEMIK-RG--GGVIINIASTRALMSEPDTEPYSASKGGLLALTHSLAISLAKYR 179 Query: 570 VNVTGV 587 + V V Sbjct: 180 IRVVAV 185 >UniRef50_P69166 Cluster: 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase; n=28; Bacteria|Rep: 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase - Mycobacterium bovis Length = 260 Score = 83.8 bits (198), Expect = 4e-15 Identities = 63/191 (32%), Positives = 95/191 (49%), Gaps = 8/191 (4%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 L GKVAL++G A G+G ++ ++ +GAKV DI E G+ V +LA + Sbjct: 5 LIGKVALVSGGARGMGASHVRAMVAEGAKVVFGDILDEEGKAVAAELADA-----ARYVH 59 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRL--------WELEVDVNLNGVIRG 401 LDVT Q+ A V F + +++NNAG +N W+ +DVNL GV G Sbjct: 60 LDVTQPAQWTAAVDTAVTAFGGLHVLVNNAGILNIGTIEDYALTEWQRILDVNLTGVFLG 119 Query: 402 TLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVT 581 + M K+ G G I+N +S V+ YTAT +A+ GLT++ + + Sbjct: 120 IRAVVKPM-KEAG--RGSIINISSIEGLAGTVACHGYTATKFAVRGLTKS--TALELGPS 174 Query: 582 GVRCLVVCPGL 614 G+R + PGL Sbjct: 175 GIRVNSIHPGL 185 >UniRef50_Q9A3M7 Cluster: Short chain dehydrogenase family protein; n=1; Caulobacter vibrioides|Rep: Short chain dehydrogenase family protein - Caulobacter crescentus (Caulobacter vibrioides) Length = 278 Score = 83.4 bits (197), Expect = 5e-15 Identities = 66/198 (33%), Positives = 94/198 (47%), Gaps = 9/198 (4%) Frame = +3 Query: 75 KVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCRLDV 254 KV ++TGAASG+G A S +L + GA + + DI+ E++ ++ ++ G R DV Sbjct: 9 KVCIVTGAASGLGRALSAQLAEAGATLIIADINFPAAEELAHRM-NQLG-VTAKPVRTDV 66 Query: 255 TDYPQFEEAFVMTVEEFNRIDIVINNAGF--------MNDRLWELEVDVNLNGVIRGTLL 410 T + T EF RID + NNAG ++ W +D+NL G I G Sbjct: 67 TLSESVRQLIEGTAAEFGRIDYLFNNAGIAVFGEIRDLSLDHWRRVIDINLMGEIYGIHY 126 Query: 411 AYRFMGKDRGGQG-GVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTGV 587 AY M K QG G IVN AS P Y A+ +A+ GL+ A + GV Sbjct: 127 AYPQMIK----QGFGHIVNVASGFGMAPGPVNSPYVASKFAVFGLSHALATE--ARAFGV 180 Query: 588 RCLVVCPGLTDSGLVXDL 641 V CPG + LV ++ Sbjct: 181 HVTVACPGFIKTPLVDNI 198 >UniRef50_Q8EMX3 Cluster: Hypothetical conserved protein; n=1; Oceanobacillus iheyensis|Rep: Hypothetical conserved protein - Oceanobacillus iheyensis Length = 254 Score = 83.4 bits (197), Expect = 5e-15 Identities = 68/212 (32%), Positives = 99/212 (46%), Gaps = 10/212 (4%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 ++GKV LITG A GIG A ++ LL GAKV+L DI+ + + E L + R V Sbjct: 1 MEGKVVLITGGAGGIGQATAKLLLDYGAKVALVDINEDSLVKAKESLHVEDDR--VFTIT 58 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF---------MNDRLWELEVDVNLNGVIR 398 +VT E TV+ F +ID+ NNAG ++ +E + +N+ GV Sbjct: 59 GNVTVEEDVENYVKQTVDRFGKIDVFFNNAGVNGPVSPITELDQATFEKIMSINVTGVFL 118 Query: 399 GTLLAYRFMGKDRGGQG-GVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVN 575 G + M K QG G IVNTAS A Y A+ +A+ G+T+ V Sbjct: 119 GLKHVMKQMKK----QGYGSIVNTASNAAYIGSAGMVSYIASKHAVAGITKTAA--LEVA 172 Query: 576 VTGVRCLVVCPGLTDSGLVXDLDKQLMSSKYE 671 G+R V P D+ ++ D+ L + E Sbjct: 173 SDGIRVNAVAPAAIDTQMLADIQNNLTPGEPE 204 >UniRef50_Q5YUD9 Cluster: Putative short chain dehydrogenase; n=1; Nocardia farcinica|Rep: Putative short chain dehydrogenase - Nocardia farcinica Length = 249 Score = 83.4 bits (197), Expect = 5e-15 Identities = 60/199 (30%), Positives = 93/199 (46%), Gaps = 4/199 (2%) Frame = +3 Query: 54 INMDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNV 233 I+ +L GKV L+TGA G G ++ L + GA+V D+D R E + +L + Sbjct: 7 ISWELNGKVVLVTGAGRGQGAEHTRRLAELGARVVAADLDVARVEAIVAELPTA-----A 61 Query: 234 LFCRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMN----DRLWELEVDVNLNGVIRG 401 + LDV + A + E F R+D+++NNAG L E E+ L+ + G Sbjct: 62 VATALDVRRAGDWSAAVDLVRERFGRLDVLVNNAGVAPRAPLSELSEEELRFVLDVDLIG 121 Query: 402 TLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVT 581 +L R + GG IVN ASTA Y A + + G TR+ + + Sbjct: 122 AILGMRAVLPLMREHGGSIVNIASTAGMTGYAGGLAYAAAKWGLRGATRSAAKE--LGPL 179 Query: 582 GVRCLVVCPGLTDSGLVXD 638 G+R +CPG D+ +V + Sbjct: 180 GIRVNAICPGAIDTAMVSE 198 >UniRef50_Q12HD3 Cluster: Short-chain dehydrogenase/reductase SDR; n=28; cellular organisms|Rep: Short-chain dehydrogenase/reductase SDR - Polaromonas sp. (strain JS666 / ATCC BAA-500) Length = 253 Score = 83.4 bits (197), Expect = 5e-15 Identities = 59/197 (29%), Positives = 94/197 (47%), Gaps = 6/197 (3%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 L+ +VA+ITGA G G ++ + GAKV + D+ +E +QV + S G+ + Sbjct: 4 LQDRVAIITGAGGGFGEGIAKHFAELGAKVVVADLRAEAAQQVAAAIESAGGQ--AIAVH 61 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRLWELEVDVNLNGVIRGTLLAYRFM 425 +DVT + V+ F R+DI++NNAG + LE D + T + ++ Sbjct: 62 VDVTQDASVADMVAAAVKRFGRLDILVNNAGTTHKNQPMLETDEKTFDRVYATNVKSIYL 121 Query: 426 GKD------RGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTGV 587 G R GGVI+N ASTA RP+ Y T A + LT+A + + Sbjct: 122 GARHAVPLFRQQGGGVIINIASTAGLRPRPGLSWYAGTKGAAITLTKAMA--VELAPDKI 179 Query: 588 RCLVVCPGLTDSGLVXD 638 R + P + ++GL+ D Sbjct: 180 RVNAINPVMGETGLLAD 196 >UniRef50_Q0SJP8 Cluster: Short chain dehydrogenase; n=1; Rhodococcus sp. RHA1|Rep: Short chain dehydrogenase - Rhodococcus sp. (strain RHA1) Length = 275 Score = 83.4 bits (197), Expect = 5e-15 Identities = 59/170 (34%), Positives = 85/170 (50%), Gaps = 8/170 (4%) Frame = +3 Query: 63 DLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFC 242 +L GKVA++TGAASGIG A + ++GA+V + DID RG+ V L + + Sbjct: 3 NLDGKVAVVTGAASGIGAATARAFAERGARVVVADIDDPRGQAVAAGLGDRGA-----YL 57 Query: 243 RLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRLWELEVDVNL----NG---VIRG 401 DV + E A + V+ F R+D ++NNAG + W D +L NG + R Sbjct: 58 HTDVRNEADVEAAVAVAVDRFGRLDCMVNNAGRVG--AWTFLEDTSLDEWENGFAMLARS 115 Query: 402 TLLAYRFMGKDRGGQG-GVIVNTASTAFARPQVSTPIYTATNYAIVGLTR 548 L + + GQG G IVN +S A R Y+A A++ LTR Sbjct: 116 AFLGTKHAARVMRGQGSGSIVNVSSVAGIRTGFGPHPYSAAKAAVLQLTR 165 >UniRef50_Q0LZB7 Cluster: NAD-dependent epimerase/dehydratase:Short-chain dehydrogenase/reductase SDR precursor; n=2; Alphaproteobacteria|Rep: NAD-dependent epimerase/dehydratase:Short-chain dehydrogenase/reductase SDR precursor - Caulobacter sp. K31 Length = 266 Score = 83.4 bits (197), Expect = 5e-15 Identities = 64/197 (32%), Positives = 89/197 (45%), Gaps = 14/197 (7%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 L+GK+A++TG A GIG A + L +GA + D+D ER + V A++ G F Sbjct: 4 LEGKIAIVTGGAGGIGAATARRLTSEGATTVIADLDLERAQAV----AAEIGHGATAF-H 58 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRL--------------WELEVDVNL 383 D E TV F R+DI++NNA ++ W+ + VNL Sbjct: 59 YDAESVDTVEALVASTVARFGRLDILLNNAAITTPQIQREDTTAVDITFDTWDRVMAVNL 118 Query: 384 NGVIRGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQ 563 G + G A M K GG I+NTAS + +S Y + ++ LTR Q Sbjct: 119 RGYLAGCKYAIPEMLK---VGGGAIINTASGSGLVGDLSRIGYGTSKAGVIALTRFIATQ 175 Query: 564 YHVNVTGVRCLVVCPGL 614 Y GVRC V PGL Sbjct: 176 Y--GRQGVRCNAVAPGL 190 >UniRef50_Q0LPB7 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Herpetosiphon aurantiacus ATCC 23779|Rep: Short-chain dehydrogenase/reductase SDR precursor - Herpetosiphon aurantiacus ATCC 23779 Length = 247 Score = 83.4 bits (197), Expect = 5e-15 Identities = 61/198 (30%), Positives = 95/198 (47%), Gaps = 9/198 (4%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 L GKVA++TG A GIG A ++ L KQGA V + DI+ + G E++ G+ C Sbjct: 2 LNGKVAIVTGGAIGIGAATAQLLAKQGAIVVIGDINEQTGLATVEQIRGNAGQAYFRHC- 60 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAG---------FMNDRLWELEVDVNLNGVIR 398 DV+ +A V + +DI+INNAG + W+ +D++L GV Sbjct: 61 -DVSHEADI-QALVQFALDQGGLDIMINNAGIGGKPAPLHLTENHNWQRVLDIDLTGVFW 118 Query: 399 GTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNV 578 G A + M GG+GG IVN AS A + Y ++ +++ + Sbjct: 119 GQKYASQAM--LAGGKGGAIVNVASIAGVAGSPNLGPYGVAKAGVIQMSKT--GAIELAS 174 Query: 579 TGVRCLVVCPGLTDSGLV 632 G+R VCPG T++ ++ Sbjct: 175 AGIRINAVCPGWTETAIL 192 >UniRef50_A1K1F4 Cluster: Short-chain dehydrogenase family protein; n=1; Azoarcus sp. BH72|Rep: Short-chain dehydrogenase family protein - Azoarcus sp. (strain BH72) Length = 253 Score = 83.4 bits (197), Expect = 5e-15 Identities = 60/198 (30%), Positives = 92/198 (46%), Gaps = 9/198 (4%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 L+ KV ++TGA SGIG A +E + ++GA V D+ + E ++ GR + R Sbjct: 5 LEQKVVIVTGAGSGIGRAAAELMAREGAIVIASDLKLDTVEDTAHRITLAGGR--AVAVR 62 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF---------MNDRLWELEVDVNLNGVIR 398 DV + + + + EF R+D NNAG + ++ + +NL V Sbjct: 63 TDVAKLAELDALHDLAIAEFGRLDGAFNNAGIPGPGVALADHEEAAFDALIAINLKAVWY 122 Query: 399 GTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNV 578 G M G GG IVNTAS + +Y AT +A++GLT+ +Y Sbjct: 123 GMKRQIELM---LPGGGGAIVNTASVGGIVGKPGLSVYCATKHAVIGLTKTAALEY--GS 177 Query: 579 TGVRCLVVCPGLTDSGLV 632 GVR VCPG+ + +V Sbjct: 178 RGVRVNAVCPGVIRTPMV 195 >UniRef50_A1CYI4 Cluster: Short chain dehydrogenase/reductase family oxidoreductase, putative; n=7; Pezizomycotina|Rep: Short chain dehydrogenase/reductase family oxidoreductase, putative - Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181)) Length = 265 Score = 83.4 bits (197), Expect = 5e-15 Identities = 60/204 (29%), Positives = 98/204 (48%), Gaps = 9/204 (4%) Frame = +3 Query: 45 YSSINMDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGR 224 + S L GK L+TG A G+G A + L GA V +CD++ +R +Q + +L + GR Sbjct: 3 HPSSENSLAGKTCLVTGGAGGLGKAIASTFLAAGANVVICDVNKDRLQQTSSEL-GETGR 61 Query: 225 KNVLFCRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFM---------NDRLWELEVDV 377 + ++D+T + V +F ++DI++NNAG M ++ LW+ + V Sbjct: 62 LRTV--KVDITSASAVQALSDEIVADFGKLDILVNNAGIMDRFDPVGDLDEALWDKVIGV 119 Query: 378 NLNGVIRGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYG 557 NL + LA R M + G I+N S A + YTA+ + +VGLT+ Sbjct: 120 NLTAPFLLSKLAVRNM-LAQPTPDGCIINIVSVAGKAGWAAGAAYTASKHGLVGLTKNTA 178 Query: 558 DQYHVNVTGVRCLVVCPGLTDSGL 629 Y G+RC + G D+ + Sbjct: 179 AFY--GNKGIRCNGLLLGGMDTNI 200 >UniRef50_A3HAH4 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Caldivirga maquilingensis IC-167|Rep: Short-chain dehydrogenase/reductase SDR - Caldivirga maquilingensis IC-167 Length = 248 Score = 83.4 bits (197), Expect = 5e-15 Identities = 63/172 (36%), Positives = 86/172 (50%), Gaps = 9/172 (5%) Frame = +3 Query: 63 DLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFC 242 +L GKVA++TGA GIG + L + GA V DI + E V E++ G+ L Sbjct: 3 NLSGKVAIVTGAGQGIGRGIALRLARDGAIVVATDITGKENE-VAEEVRKLGGQGMAL-- 59 Query: 243 RLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF--------MNDRLWELEVDVNLNGVIR 398 RLDVTD EE +++ IDI++NNAG M W ++VNLNGV Sbjct: 60 RLDVTDGKMAEEVARTVFDKYGHIDILVNNAGIYPFKPFMEMTFNDWYRVINVNLNGVFN 119 Query: 399 GTLLAYRFMGKDRGGQGGVIVNTASTAFA-RPQVSTPIYTATNYAIVGLTRA 551 T +M K + G+ I+N AS A A + Y+A+ IVG TRA Sbjct: 120 VTRAVVPYMVKQKNGR---IINIASIAGAVMGFMGLTHYSASKAGIVGFTRA 168 >UniRef50_A2BJK2 Cluster: Short chain dehydrogenase; n=1; Hyperthermus butylicus DSM 5456|Rep: Short chain dehydrogenase - Hyperthermus butylicus (strain DSM 5456 / JCM 9403) Length = 243 Score = 83.4 bits (197), Expect = 5e-15 Identities = 60/199 (30%), Positives = 99/199 (49%), Gaps = 9/199 (4%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSER-GEQVTEKLASKYGRKNVL 236 M ++G V L+TG++ GIG A + E ++GAK + + S R + T +L + G L Sbjct: 1 MRVQGSVVLVTGSSRGIGRAVAVEAARRGAKGVVVNYVSRRDAAEETARLVKEAGAVP-L 59 Query: 237 FCRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRL--------WELEVDVNLNGV 392 R DV+ Y + + +E++ R+D+V+NNAG + +L W+ ++V+ G Sbjct: 60 VVRADVSVYEEARKLVEAAIEKWGRLDVVVNNAGILEPKLFEDMKPRDWQRMIEVHFYGA 119 Query: 393 IRGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHV 572 + A +M R G GGVIVN AS RP+ Y+A A++ T A + + Sbjct: 120 LNVAHAAIPYM--KRNG-GGVIVNIASVLGLRPEPEASHYSAAKAALIAWTIAVAKE--L 174 Query: 573 NVTGVRCLVVCPGLTDSGL 629 +R V PG D+ + Sbjct: 175 ADYNIRVFAVAPGGVDTDM 193 >UniRef50_Q7W7A0 Cluster: Probable 3-oxoacyl-[acyl-carrier protein] reductase; n=3; Bordetella|Rep: Probable 3-oxoacyl-[acyl-carrier protein] reductase - Bordetella parapertussis Length = 248 Score = 83.0 bits (196), Expect = 7e-15 Identities = 69/207 (33%), Positives = 100/207 (48%), Gaps = 8/207 (3%) Frame = +3 Query: 57 NMDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVL 236 N L+G+VAL+TG A GIGLA L +GA++ + DI GE+ A+ G + L Sbjct: 3 NERLQGRVALVTGGAGGIGLAVCRRLQAEGARIVVGDI----GEERVLAAAASLG-EGAL 57 Query: 237 FCRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRL--------WELEVDVNLNGV 392 LDV D + A + ++DIV+N AG + DR W +DVNL G Sbjct: 58 GVFLDVADRQSWAAAKRAVDAQGWQVDIVVNVAGIVRDRSLAKMSDAEWSAVIDVNLRGT 117 Query: 393 IRGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHV 572 G A+ ++G +RG G I+N ASTA Y+A IVGLTR Sbjct: 118 WLGCQSAFAWIG-ERG--WGRIINVASTAIF-GAYGQANYSAAKAGIVGLTRTAA--LEG 171 Query: 573 NVTGVRCLVVCPGLTDSGLVXDLDKQL 653 G+ V PG+ ++ ++ D+ Q+ Sbjct: 172 AKRGILVNAVAPGIVETAILADVPDQV 198 >UniRef50_Q7W2M6 Cluster: Alcohol dehydrogenase; n=15; cellular organisms|Rep: Alcohol dehydrogenase - Bordetella parapertussis Length = 252 Score = 83.0 bits (196), Expect = 7e-15 Identities = 61/199 (30%), Positives = 97/199 (48%), Gaps = 6/199 (3%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLF 239 M L GK A++TGA SG G + ++GAKV + DI+ G++V + + G+ +F Sbjct: 1 MRLNGKTAIVTGAGSGFGEGIAATFAREGAKVVVADINEAGGQRVAAAINAAGGQ--AVF 58 Query: 240 CRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAG--FMNDRLWELEVDV--NLNGV-IRGT 404 R DV+D T++ F +DIV+NNAG N + E+E D + + ++ Sbjct: 59 VRADVSDNAAVANLLAATLKAFGGLDIVVNNAGTTHRNRPMLEVEEDEFDRIYAINVKSI 118 Query: 405 LLAYRFMGKD-RGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVT 581 L R M R GG +N ASTA RP+ Y + A+V +++ + + Sbjct: 119 YLTARHMVPHFRAHGGGSFINIASTAAIRPRPGLTWYNGSKGAVVTTSKSMAAELGPDNI 178 Query: 582 GVRCLVVCPGLTDSGLVXD 638 V C V P + +GL+ D Sbjct: 179 RVNC--VNPVIGATGLLAD 195 >UniRef50_Q46NM9 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Ralstonia eutropha JMP134|Rep: Short-chain dehydrogenase/reductase SDR - Ralstonia eutropha (strain JMP134) (Alcaligenes eutrophus) Length = 263 Score = 83.0 bits (196), Expect = 7e-15 Identities = 62/191 (32%), Positives = 90/191 (47%), Gaps = 8/191 (4%) Frame = +3 Query: 63 DLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFC 242 DL+GKVAL+TGA G+GL ++ L + G V L GE + L + G+ V+ Sbjct: 14 DLEGKVALVTGAFGGLGLHFARTLARAGCGVVLAGRRVGEGEALLADLRKQGGQGCVV-- 71 Query: 243 RLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF--------MNDRLWELEVDVNLNGVIR 398 LDV D + AF E + IV+N+AG + + W+ +D NLNG R Sbjct: 72 ALDVRDPASVDAAFEAARRELGPVQIVVNSAGIATTGAAMDVTEAQWQSVIDTNLNGAWR 131 Query: 399 GTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNV 578 A R M +D G I+N AS R P YTA ++ LTR+ ++ + Sbjct: 132 VAQRAARMM-RDTDTHGS-IINIASILGLRVAQQVPAYTAAKAGLIHLTRSLALEWARH- 188 Query: 579 TGVRCLVVCPG 611 G+R + PG Sbjct: 189 -GIRVNALAPG 198 >UniRef50_Q39TI0 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Geobacter metallireducens (strain GS-15 / ATCC 53774 / DSM 7210) Length = 258 Score = 83.0 bits (196), Expect = 7e-15 Identities = 71/232 (30%), Positives = 110/232 (47%), Gaps = 9/232 (3%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 ++GKVA++TGAASG+G A + L ++GA+V + DI+ + G+ + L + +F R Sbjct: 4 VEGKVAIVTGAASGLGAASARLLAREGARVVITDINVKDGQALANSLG-----EGAIFLR 58 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFM--------NDRLWELEVDVNLNGVIRG 401 DV+D Q+ T+ F R+DI++NNAG + W V +G G Sbjct: 59 HDVSDEAQWVAIIEQTLSRFGRLDILVNNAGVVVVADVEHTTVEDWRFVNAVGTDGTFFG 118 Query: 402 TLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVT 581 A M R GG IVN +S A Y+A+ AI +T++ N Sbjct: 119 CKHAIPAM---RRSGGGSIVNLSSLAGIGGYPLVFAYSASKGAIRAMTKSVAVHCAQNKY 175 Query: 582 GVRCLVVCPGLTDSGLVXDLDKQLMSSKYETAWLEDITDSKCRALIT-LGKP 734 +RC + PG G++ L + + S TA D + K R L + LG+P Sbjct: 176 NIRCNSIHPG----GILTPLVEGFIKSAVGTA---DASMDKARDLFSKLGEP 220 >UniRef50_Q396N3 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 / R18194)) Length = 262 Score = 83.0 bits (196), Expect = 7e-15 Identities = 64/206 (31%), Positives = 96/206 (46%), Gaps = 9/206 (4%) Frame = +3 Query: 63 DLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFC 242 DL+GKVA ITG A GIG + L GA V++ D+ S+ E + E++ ++ G+ F Sbjct: 9 DLRGKVAAITGGARGIGAETARTLAAAGASVAILDVLSQPAEALVEEIRAQGGQ--AAFW 66 Query: 243 RLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRL---------WELEVDVNLNGVI 395 LDVT F V F R+D+++NNAG + W+ +DVN+NGV Sbjct: 67 SLDVTHEADVARVFGEIVAHFGRLDVLVNNAGIEGHNVPTHELTLAQWQRVLDVNVNGVF 126 Query: 396 RGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVN 575 T A + D G GG IVN +S P Y A+ A+ + + D Sbjct: 127 LCTRAAIPHI--DAAG-GGSIVNLSSMYGIVGGPDVPAYHASKAAVRMMAKV--DAMLYA 181 Query: 576 VTGVRCLVVCPGLTDSGLVXDLDKQL 653 +R V PG + ++ D +Q+ Sbjct: 182 AKNIRANSVHPGYIRTPMLEDAFRQM 207 >UniRef50_Q2RUY0 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Rhodospirillum rubrum ATCC 11170|Rep: Short-chain dehydrogenase/reductase SDR - Rhodospirillum rubrum (strain ATCC 11170 / NCIB 8255) Length = 260 Score = 83.0 bits (196), Expect = 7e-15 Identities = 64/194 (32%), Positives = 93/194 (47%), Gaps = 12/194 (6%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 L+ KVAL+TG A+GIG A + L GA+V + D+D E+ E + +VL Sbjct: 7 LRDKVALVTGGANGIGRAAARALYGAGARVVIADLDQMAAERAAEAMGG-----DVLGLP 61 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF--------MNDRLWELEVDVNLNGVIRG 401 +DV D + + IDI++ NAG + D W DVN GV Sbjct: 62 VDVRDRTSMQTCVDRAIASCGGIDILVANAGVSSMRKAVELTDEDWAFNFDVNAKGVFLA 121 Query: 402 TLLAYR-FMGKDRGGQGGVIVNTASTAFARPQVSTPI---YTATNYAIVGLTRAYGDQYH 569 L R F+ G+ GVIVNTAS A +V P+ Y A+ +A++G T++ + Sbjct: 122 NQLVVRHFLAT---GRKGVIVNTASLA---AKVGAPLLAHYAASKFAVLGWTQSLARE-- 173 Query: 570 VNVTGVRCLVVCPG 611 + G+R VCPG Sbjct: 174 LAPEGIRVNAVCPG 187 >UniRef50_Q0VQZ0 Cluster: Oxidoreductase; n=4; Gammaproteobacteria|Rep: Oxidoreductase - Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM 11573) Length = 256 Score = 83.0 bits (196), Expect = 7e-15 Identities = 59/198 (29%), Positives = 96/198 (48%), Gaps = 5/198 (2%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLF 239 +D GK ALITGAASG G ++EL K+GA + L DI+ + + + LA + G K V Sbjct: 5 LDFTGKTALITGAASGFGKLLAQELGKRGAALVLGDINMDALNPLADTLAEQ-GVK-VAA 62 Query: 240 CRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMN-----DRLWELEVDVNLNGVIRGT 404 R DV+ + + +F +D+ +NNAG + +L E +D +N ++G Sbjct: 63 LRCDVSSEADCKAMVDAALSQFGHLDLAVNNAGIAHGFIPFTQLSEEVLDQQMNVNVKGV 122 Query: 405 LLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTG 584 + + GG IVN +S A Y+A +A++GLTR +Y Sbjct: 123 MFGMKHQIDAMKVGGGSIVNVSSMAGLGGAPKIGAYSAAKHAVIGLTRTAAVEYAKR--N 180 Query: 585 VRCLVVCPGLTDSGLVXD 638 +R +CP T + ++ + Sbjct: 181 IRVNAICPFYTHTPMLDE 198 >UniRef50_A4XED1 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Alphaproteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Novosphingobium aromaticivorans (strain DSM 12444) Length = 269 Score = 83.0 bits (196), Expect = 7e-15 Identities = 63/199 (31%), Positives = 92/199 (46%), Gaps = 10/199 (5%) Frame = +3 Query: 51 SINMDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKN 230 +I MD GKVA++TG A GIG A + L +GA V + DI ER E + LA Sbjct: 5 AIRMD--GKVAIVTGGAGGIGEATARLLTARGACVVIADIAFERAEALAADLA------G 56 Query: 231 VLFCRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRLWELEVDVNLNGV------ 392 + LD+ E TV F R+D++ NNA + + + + DV G Sbjct: 57 AIALPLDLEQEQSVETLVERTVAHFGRLDVLHNNAALLGPEIAQADGDVERMGTALWDRT 116 Query: 393 ----IRGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGD 560 +RGT++A R G IVNT S + + Y+++ A++ +TRA Sbjct: 117 FAVNVRGTMIACRAALPHLRETRGCIVNTVSNLALQGHLIQAAYSSSKAAVIQMTRAIAA 176 Query: 561 QYHVNVTGVRCLVVCPGLT 617 + GVRC V PG+T Sbjct: 177 SH--GKAGVRCNAVAPGMT 193 >UniRef50_A1UD58 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=2; Mycobacterium|Rep: Short-chain dehydrogenase/reductase SDR precursor - Mycobacterium sp. (strain KMS) Length = 275 Score = 83.0 bits (196), Expect = 7e-15 Identities = 63/196 (32%), Positives = 93/196 (47%), Gaps = 12/196 (6%) Frame = +3 Query: 66 LKGKVALITGAAS------GIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRK 227 L +VAL+TGA + IG A + E++ +GA+V L DI+ E + E+L KYG Sbjct: 4 LSNRVALVTGATAVEPGGLNIGGAAATEVVAEGARVVLADINIEGASALAEQLNQKYGPD 63 Query: 228 NVLFCRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFM-----NDRLWELEVDVNLNGV 392 + + D+ D + TV F +ID++ N AG + +EV ++ V Sbjct: 64 VAIAVQTDLRDEDAIQRLVATTVSTFGKIDVLFNIAGVFPAGDGDVATMPIEVWDDVMAV 123 Query: 393 -IRGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYH 569 +R +L + +GG IVNTAST S Y AT A++ LT+ QY Sbjct: 124 NVRSAMLTTKHALPHLRVEGGSIVNTASTHAFAGDTSLTGYGATKAALLALTKYTATQY- 182 Query: 570 VNVTGVRCLVVCPGLT 617 VRC +CPG T Sbjct: 183 -GRERVRCNAICPGTT 197 >UniRef50_Q0D3U7 Cluster: Os07g0665000 protein; n=18; Poales|Rep: Os07g0665000 protein - Oryza sativa subsp. japonica (Rice) Length = 310 Score = 83.0 bits (196), Expect = 7e-15 Identities = 68/198 (34%), Positives = 98/198 (49%), Gaps = 11/198 (5%) Frame = +3 Query: 48 SSINMDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRK 227 SS + L GKVA+ITGAASGIG A ++E ++ GAKV + DI + G V A++ G Sbjct: 37 SSSSRKLDGKVAVITGAASGIGEATAKEFVRNGAKVIIADIQDDLGRAV----AAELGAD 92 Query: 228 NVLFCRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMN----DRLWELEVD------- 374 + DVT A + V R+D+V +NAG + L L++D Sbjct: 93 AASYTHCDVTVEKDVAAAVDLAVARHGRLDVVYSNAGVIGAPAPASLAALDLDEYDRVMA 152 Query: 375 VNLNGVIRGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAY 554 VN ++ A R M R G I+ TAS+A V++P+Y+ + AIVG+ RA Sbjct: 153 VNARSMLACVKHAARVMAPRR---AGCILCTASSAAVLGGVASPVYSMSKAAIVGMVRAV 209 Query: 555 GDQYHVNVTGVRCLVVCP 608 Q + GVR + P Sbjct: 210 ARQ--LARDGVRVNAISP 225 >UniRef50_P76633 Cluster: Uncharacterized oxidoreductase ygcW; n=23; Bacteria|Rep: Uncharacterized oxidoreductase ygcW - Escherichia coli (strain K12) Length = 261 Score = 83.0 bits (196), Expect = 7e-15 Identities = 58/185 (31%), Positives = 93/185 (50%), Gaps = 11/185 (5%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 LKGK A++TG SG+G A++ L K GA + + + GE T+++ K G V F + Sbjct: 16 LKGKTAIVTGGNSGLGQAFAMALAKAGANIFIPSFVKDNGE--TKEMIEKQG-VEVDFMQ 72 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF--MNDRL------WELEVDVNLNGVIRG 401 + +T ++ E F +DI++NNAG +N L W+ +DVNL Sbjct: 73 VGITAEGAPQKIIAACCERFGTVDILVNNAGICKLNKVLDFGRADWDPMIDVNLTAAFEL 132 Query: 402 TLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGD---QYHV 572 + A + M + G+ I+N S +P Y+AT +A+ G T+AY D QY++ Sbjct: 133 SYEAAKIMIPQKSGK---IINICSLFSYLGGQWSPAYSATKHALAGFTKAYCDELGQYNI 189 Query: 573 NVTGV 587 V G+ Sbjct: 190 QVNGI 194 >UniRef50_Q815Q8 Cluster: Short chain dehydrogenase; n=1; Bacillus cereus ATCC 14579|Rep: Short chain dehydrogenase - Bacillus cereus (strain ATCC 14579 / DSM 31) Length = 260 Score = 82.6 bits (195), Expect = 9e-15 Identities = 63/213 (29%), Positives = 106/213 (49%), Gaps = 9/213 (4%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 L KV +ITGA+ GIG + L +G V L + + E V +K+ + G V+ Sbjct: 24 LMKKVVVITGASDGIGYETAIYLASKGMIVVLSSRNKTKLESVRKKIHTMGGEAIVI--P 81 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFM------NDRLWELE--VDVNLNGVIRG 401 D++ + E+ T+E + RID++INNAG M N + E +DVN+ GV+ G Sbjct: 82 ADISKAKEVEQLINKTIELYGRIDVLINNAGVMPLSWLKNFDIREASSAIDVNIKGVLYG 141 Query: 402 TLLAYRFM-GKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNV 578 M +D G +IVN ST IY+AT +A+ +T+ + ++ Sbjct: 142 IRYVLPHMLTRDEG----IIVNIGSTVSYEIPPYGVIYSATKHAVNAITKGLHKELSMSK 197 Query: 579 TGVRCLVVCPGLTDSGLVXDLDKQLMSSKYETA 677 + VR +++ PG ++ L+ + + L S Y+T+ Sbjct: 198 SKVRLILISPGPVETNLMKNTNAGLKSQTYKTS 230 >UniRef50_Q7VV50 Cluster: Probable short chain dehydrogenase; n=1; Bordetella pertussis|Rep: Probable short chain dehydrogenase - Bordetella pertussis Length = 249 Score = 82.6 bits (195), Expect = 9e-15 Identities = 63/196 (32%), Positives = 97/196 (49%), Gaps = 9/196 (4%) Frame = +3 Query: 63 DLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFC 242 DL GK+A++TGA GIG A L +QGA+V D+D + Q A + ++V Sbjct: 5 DLAGKIAVVTGAGGGIGRAIVAALREQGARVVATDLDPQALAQ-----AMRESGQDVDCR 59 Query: 243 RLDVTDYPQFEEAFVMTV-EEFNRIDIVINNAGFM--------NDRLWELEVDVNLNGVI 395 LDV D P A V +++ +DI +NNAGFM +++ W+ +D+NL G Sbjct: 60 ALDVAD-PAASRALADAVAQQYGVLDIWVNNAGFMARMPALELDEQTWQRTLDINLKGTF 118 Query: 396 RGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVN 575 G A R M R G G I+N +S A +P+ + Y + + LT+ ++ + Sbjct: 119 FGAQAAARHM--TRQG-SGAIINLSSYAGIKPRPNCADYASAKAGVAHLTQCLALEW--S 173 Query: 576 VTGVRCLVVCPGLTDS 623 GVR + PG D+ Sbjct: 174 PLGVRVNAIAPGFIDT 189 >UniRef50_A6C1M0 Cluster: Short chain dehydrogenase; n=1; Planctomyces maris DSM 8797|Rep: Short chain dehydrogenase - Planctomyces maris DSM 8797 Length = 264 Score = 82.6 bits (195), Expect = 9e-15 Identities = 56/189 (29%), Positives = 90/189 (47%), Gaps = 8/189 (4%) Frame = +3 Query: 69 KGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCRL 248 K ++ +ITGA +GIG A + + + GA V D++ Q T + R + + Sbjct: 8 KDQIVVITGAGNGIGRATAIMMAESGAHVLAGDLNHLPENQAT------FSRLGITEVKC 61 Query: 249 DVTDYPQFEEAFVMTVEEFNRIDIVINNAGF--------MNDRLWELEVDVNLNGVIRGT 404 DV + V+++ RID+++NNAG ++ W+ +D NL G G Sbjct: 62 DVRQEADIQALIDQAVQQYGRIDVLVNNAGIGMVKPIHQVSVEEWDACIDTNLKGTFLGC 121 Query: 405 LLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTG 584 A R M GG I+NTAS A P+ P+Y+ + +A+V LT + G + + Sbjct: 122 KHAIRHM---LASGGGSIINTASNAGLLPRAHDPVYSISKHAVVALTESLGLCHGKDNIR 178 Query: 585 VRCLVVCPG 611 + C VCPG Sbjct: 179 INC--VCPG 185 >UniRef50_A5V1Y0 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Roseiflexus sp. RS-1 Length = 246 Score = 82.6 bits (195), Expect = 9e-15 Identities = 57/209 (27%), Positives = 99/209 (47%), Gaps = 5/209 (2%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLF 239 M LKGKVA++TGA GIG A + ++GA V++ DI+ E ++ GR L Sbjct: 1 MRLKGKVAIVTGAGHGIGKATAIAFAREGAHVAVVDINMAGAEATVAEITRLDGR--ALA 58 Query: 240 CRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMND----RLWELEVDVNLNGVIRGTL 407 + DV+ E + RID+++NNAG D ++ E + D +N ++G Sbjct: 59 VQADVSQAASVESMVETVLAWGGRIDVLLNNAGITRDARLVKMTEQQWDAVINVNLKGVW 118 Query: 408 LAYRFMGKDRGGQG-GVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTG 584 L R + QG G I+N +S Y AT ++ +T+ + + + +G Sbjct: 119 LCARAVAPHMSAQGSGSIINVSSIVGLYGNFGQSNYAATKGGVIAMTKTWARE--LGPSG 176 Query: 585 VRCLVVCPGLTDSGLVXDLDKQLMSSKYE 671 VR V PG + ++ + ++++ + E Sbjct: 177 VRVNAVTPGFIATEMITTIPEKVIQTVCE 205 >UniRef50_Q8EPA2 Cluster: Hypothetical conserved protein; n=1; Oceanobacillus iheyensis|Rep: Hypothetical conserved protein - Oceanobacillus iheyensis Length = 255 Score = 82.2 bits (194), Expect = 1e-14 Identities = 65/212 (30%), Positives = 98/212 (46%), Gaps = 9/212 (4%) Frame = +3 Query: 69 KGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCRL 248 K KV LITGAA GIGL ++ +GAK++L D+ +E EK AS+ + +L Sbjct: 3 KDKVVLITGAAGGIGLEAAKAYAHEGAKLALVDLKNE----ALEKAASEIETEEILLITA 58 Query: 249 DVTDYPQFEEAFVMTVEEFNRIDIVINNAG----FMN-----DRLWELEVDVNLNGVIRG 401 +V + T E++ +IDI INNAG F N + DVN+ GV G Sbjct: 59 NVGKEEDVKNYVDRTKEQYGKIDIFINNAGINGQFKNIIEQTKENFSNVFDVNVMGVFFG 118 Query: 402 TLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVT 581 + M + GV++NTAS Y A+ +A++GL + + Sbjct: 119 MKYVLQVMKLQK---SGVVINTASNGGLLGAPGMSAYVASKHAVIGLNKTAA--LEMAEY 173 Query: 582 GVRCLVVCPGLTDSGLVXDLDKQLMSSKYETA 677 GVR V P ++ ++ ++K M K E A Sbjct: 174 GVRVNAVAPSGVNTEMMRSIEKNAMGDKAEEA 205 >UniRef50_Q5P8S7 Cluster: Cyclohexanol dehydrogenase; n=3; Bacteria|Rep: Cyclohexanol dehydrogenase - Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum (strain EbN1)) Length = 248 Score = 82.2 bits (194), Expect = 1e-14 Identities = 63/203 (31%), Positives = 90/203 (44%), Gaps = 9/203 (4%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLF 239 M L+GK AL+TGA +GIG + +GA V + DI E G + + K G+ +F Sbjct: 1 MLLEGKTALVTGAGNGIGRTIALTYAAEGANVVVSDISDEWGRETLALIEGKGGK--AVF 58 Query: 240 CRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF---------MNDRLWELEVDVNLNGV 392 D +E F R+DI NNAG D W+ + +NL+GV Sbjct: 59 QHADTAHPEDHDELIAAAKRAFGRLDIACNNAGISGEFTPTAETTDAQWQRVIGINLSGV 118 Query: 393 IRGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHV 572 G R M + G GG IVN +S A YTA + +VGLT+ +Y Sbjct: 119 FYGVRAQIRAM-LETG--GGAIVNISSIAGQIGIEGITPYTAAKHGVVGLTKTVAWEY-- 173 Query: 573 NVTGVRCLVVCPGLTDSGLVXDL 641 G+R V P ++ LV ++ Sbjct: 174 GSKGIRINSVGPAFINTTLVQNV 196 >UniRef50_Q83ZE7 Cluster: Short-chain dehydrogenase/redutase; n=1; Terrabacter sp. DBF63|Rep: Short-chain dehydrogenase/redutase - Terrabacter sp. DBF63 Length = 252 Score = 82.2 bits (194), Expect = 1e-14 Identities = 60/203 (29%), Positives = 92/203 (45%), Gaps = 9/203 (4%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 L GKVAL+TG GIG ++ L+ GA+V + D+ + G E + G V F R Sbjct: 5 LDGKVALVTGGGGGIGRETAKVLVDHGARVVVADLSEDAGNGTLEYID---GGDAVAFVR 61 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF---------MNDRLWELEVDVNLNGVIR 398 DVTD + V+ + R+DI NNAG + ++ + VNL GV Sbjct: 62 ADVTDLASMQHLVQAAVDRYGRLDIAHNNAGIEVTGPDLADVTVEQFDKVIAVNLTGVFI 121 Query: 399 GTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNV 578 M GG I+NTAS+ Y + + ++GLTRA +Y + Sbjct: 122 SMKAEIPQMLAQGGGS---IINTASSLGQAALAHQSAYVTSKHGVIGLTRAAAVEY--SD 176 Query: 579 TGVRCLVVCPGLTDSGLVXDLDK 647 G+R V PG+ + ++ L++ Sbjct: 177 KGIRVNAVLPGVIQTPMIDALEE 199 >UniRef50_Q0SK66 Cluster: Short chain dehydrogenase; n=5; Bacteria|Rep: Short chain dehydrogenase - Rhodococcus sp. (strain RHA1) Length = 276 Score = 82.2 bits (194), Expect = 1e-14 Identities = 68/207 (32%), Positives = 96/207 (46%), Gaps = 21/207 (10%) Frame = +3 Query: 54 INMDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDI-----------DSERGEQVTE 200 ++ DL GK A +TGAA GIG A + E GA + L DI S+ T Sbjct: 1 MSADLAGKTAFVTGAARGIGRACAVEFAAAGADLMLVDITRNLPGVPYPLGSQSQLDYTA 60 Query: 201 KLASKYGRKNVLFCRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF----------MND 350 +L ++G VL +DV + + A + E F R+D+++NNAG + + Sbjct: 61 ELCREHG-ATVLTQAVDVRELAEITAAVQVAHERFGRLDVLLNNAGIAAPSGKAAHDIAE 119 Query: 351 RLWELEVDVNLNGVIRGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYA 530 W L +DV+L+G R A R M R G I+N ASTA Y A + Sbjct: 120 SEWRLMIDVDLSGAWRTIATAGRIMVTQRSGS---IINIASTAGLVGYRHFAGYVAAKHG 176 Query: 531 IVGLTRAYGDQYHVNVTGVRCLVVCPG 611 +VGLT+A Y +GVR +CPG Sbjct: 177 LVGLTKAVALDY--APSGVRVNALCPG 201 >UniRef50_Q0RYT4 Cluster: 3-oxoacyl-[acyl-carrier-protein] reductase; n=1; Rhodococcus sp. RHA1|Rep: 3-oxoacyl-[acyl-carrier-protein] reductase - Rhodococcus sp. (strain RHA1) Length = 260 Score = 82.2 bits (194), Expect = 1e-14 Identities = 62/223 (27%), Positives = 108/223 (48%), Gaps = 10/223 (4%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 L+ K+A++TGA+ G+G + EL +GA V D+ S T + A G + Sbjct: 4 LENKIAIVTGASRGLGEGIAVELAARGATVVCADLHSAEDTATTLQSA---GSPKSSSAK 60 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF--------MNDRLWELEVDVNLNGVIRG 401 +DV+ +E TVE R+DI++NNAG + D + +DVN+ GV G Sbjct: 61 VDVSSAASVDELVGSTVETHGRLDIMVNNAGIYTYGAIADVTDDDFRRTMDVNIGGVFNG 120 Query: 402 TLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVT 581 + A R M + + G+ I+NTAS + + +Y+A+ A++ +T+A G + Sbjct: 121 SRAAARVMKEQKSGR---IINTASQLGKLARPNEGVYSASKAAVILMTQALG--LELAPY 175 Query: 582 GVRCLVVCPGLTDSGLVXDLDKQLMSSKYET--AWLEDITDSK 704 + +CPG + ++ ++ S+ T L+D D+K Sbjct: 176 NITVNAICPGCMHTEMMEKSFAEIAQSEGITLEQKLQDYLDAK 218 >UniRef50_A4RFU8 Cluster: Putative uncharacterized protein; n=1; Magnaporthe grisea|Rep: Putative uncharacterized protein - Magnaporthe grisea (Rice blast fungus) (Pyricularia grisea) Length = 351 Score = 82.2 bits (194), Expect = 1e-14 Identities = 63/221 (28%), Positives = 98/221 (44%), Gaps = 19/221 (8%) Frame = +3 Query: 69 KGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCRL 248 +GKV ITG +SGIGL +E LL +G +V++ ++RGE+ L G K VLF + Sbjct: 14 QGKVIYITGGSSGIGLHLAEHLLSKGWRVAISARQAQRGEEAARAL-DPTGNK-VLFVKC 71 Query: 249 DVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDR-----LWELE--------------V 371 DVT Y Q AF+ + + R+D + NAG + + + E + Sbjct: 72 DVTSYEQQAAAFLAVWQRWGRLDAFVANAGVTDSESRYNLVGKAEAKVEDVPREPDTACL 131 Query: 372 DVNLNGVIRGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRA 551 D L V+ GT+LA +M + GG I+ T S P P Y A R+ Sbjct: 132 DTGLKAVVHGTVLAVHYMRHNSPAPGGEILVTGSVFSVYPGPVFPEYAAAKAGSANWVRS 191 Query: 552 YGDQYHVNVTGVRCLVVCPGLTDSGLVXDLDKQLMSSKYET 674 + + +CPG ++ ++ D DK + + T Sbjct: 192 MAPVL-LGKDNITINEICPGPYNTNIMPDFDKAFLPEHHAT 231 >UniRef50_Q3IU31 Cluster: Probable dehydrogenase/ reductase 4; n=1; Natronomonas pharaonis DSM 2160|Rep: Probable dehydrogenase/ reductase 4 - Natronomonas pharaonis (strain DSM 2160 / ATCC 35678) Length = 253 Score = 82.2 bits (194), Expect = 1e-14 Identities = 63/199 (31%), Positives = 94/199 (47%), Gaps = 9/199 (4%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLF 239 M + ITGA SGIG A + ++ ++GA V DI+ + G + + + G + F Sbjct: 1 MRFENDTVFITGAGSGIGRATALKVAREGAFVVATDINEDGGRETVDAVEDAGG--DAAF 58 Query: 240 CRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF---------MNDRLWELEVDVNLNGV 392 LDVTD +F+ +E+ +D +INNAG + + +E +DVNL GV Sbjct: 59 HELDVTDADEFKAVVETAADEYG-LDAMINNAGVGHPPAYTEDVTETTFEYVLDVNLRGV 117 Query: 393 IRGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHV 572 G A + K +G G IVN S A +Y+ T A++ LTRA + Sbjct: 118 WNGCQAALPHL-KSQG--EGAIVNVGSLASFLGLPKQAVYSLTKGAVLNLTRAIASE--A 172 Query: 573 NVTGVRCLVVCPGLTDSGL 629 GVR VCPG ++ L Sbjct: 173 GRDGVRANAVCPGFIETPL 191 >UniRef50_Q9KQH7 Cluster: 3-oxoacyl-[acyl-carrier-protein] reductase; n=225; cellular organisms|Rep: 3-oxoacyl-[acyl-carrier-protein] reductase - Vibrio cholerae Length = 244 Score = 82.2 bits (194), Expect = 1e-14 Identities = 64/205 (31%), Positives = 94/205 (45%), Gaps = 8/205 (3%) Frame = +3 Query: 60 MDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLF 239 M+L+GKVAL+TGA+ GIG A +E L ++GAKV + SE G Q S Y N Sbjct: 1 MNLEGKVALVTGASRGIGKAIAELLAERGAKV-IGTATSESGAQA----ISDYLGDNGKG 55 Query: 240 CRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRL--------WELEVDVNLNGVI 395 L+VT+ E +EF +DI++NNAG D L W ++ NL + Sbjct: 56 MALNVTNPESIEAVLKAITDEFGGVDILVNNAGITRDNLLMRMKEEEWSDIMETNLTSIF 115 Query: 396 RGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVN 575 R + R M K R G+ I+N S Y A ++G T++ + V Sbjct: 116 RLSKAVLRGMMKKRQGR---IINVGSVVGTMGNAGQANYAAAKAGVIGFTKSMARE--VA 170 Query: 576 VTGVRCLVVCPGLTDSGLVXDLDKQ 650 GV V PG ++ + L+ + Sbjct: 171 SRGVTVNTVAPGFIETDMTKALNDE 195 >UniRef50_P39071 Cluster: 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase; n=31; Bacteria|Rep: 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase - Bacillus subtilis Length = 261 Score = 82.2 bits (194), Expect = 1e-14 Identities = 62/200 (31%), Positives = 92/200 (46%), Gaps = 8/200 (4%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 ++GK+A ITGAA GIG A + L QGA ++ D + E+ E+V L ++ R F Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAE-ARHAEAF-P 63 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF--------MNDRLWELEVDVNLNGVIRG 401 DV D +E E IDI++N AG ++D WE VN GV Sbjct: 64 ADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNA 123 Query: 402 TLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVT 581 + ++M DR + G IV S P+ S Y ++ A V T+ G + Sbjct: 124 SRSVSKYM-MDR--RSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLG--LELAEY 178 Query: 582 GVRCLVVCPGLTDSGLVXDL 641 +RC +V PG T++ + L Sbjct: 179 NIRCNIVSPGSTETDMQWSL 198 >UniRef50_Q97M39 Cluster: 2 deoxy-D-gluconate 3-dehydrogenase; n=9; Bacteria|Rep: 2 deoxy-D-gluconate 3-dehydrogenase - Clostridium acetobutylicum Length = 260 Score = 81.8 bits (193), Expect = 2e-14 Identities = 56/174 (32%), Positives = 88/174 (50%), Gaps = 8/174 (4%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 LKGKVA++TG +G+G Y+ L K GA + + + E T KL GRK V F + Sbjct: 15 LKGKVAIVTGGNTGLGQGYALALAKAGADLFIVTHGTNWDE--TRKLIEDEGRK-VEFYK 71 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFM--------NDRLWELEVDVNLNGVIRG 401 D++ F +E + R+DI++NNAG + D WE ++ NLN + Sbjct: 72 ADLSKKESIPGIFDKCMELYGRLDILVNNAGTIRRAPITEYRDEDWEYIINTNLNSIYHL 131 Query: 402 TLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQ 563 + A + M K G+ I+N AS + P YTA+ + + GLT+A+ ++ Sbjct: 132 SQRAAKIMIKQGSGK---IINIASMLSFQGGKFVPPYTASKHGVAGLTKAFANE 182 >UniRef50_Q883G7 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family; n=6; Proteobacteria|Rep: Oxidoreductase, short chain dehydrogenase/reductase family - Pseudomonas syringae pv. tomato Length = 266 Score = 81.8 bits (193), Expect = 2e-14 Identities = 60/193 (31%), Positives = 94/193 (48%), Gaps = 9/193 (4%) Frame = +3 Query: 72 GKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCRLD 251 GK +ITGA GIG +E ++GA + L D ER +E+LAS+Y N L +D Sbjct: 7 GKTVVITGACRGIGAGIAERFAQEGANLVLASNDLERMTFSSEQLASEYS-VNSLALGID 65 Query: 252 VTDYPQFEEAFVMTVEEFNRIDIVINNAGFMN-DRL-------WELEVDVNLNGVIRGTL 407 VTD + + E F ID+ + NAG + D ++ + VN GV G Sbjct: 66 VTDEADIQRLYQSAHERFGSIDVSVQNAGIITIDHCESMPRADFDKVLQVNTTGVWLGCR 125 Query: 408 LAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYG-DQYHVNVTG 584 A R+M K G+ ++NT+S + + TP Y A+ ++G+T++ + N+T Sbjct: 126 EAARYMVKQGSGR---LINTSSGQGRQGFIYTPHYAASKMGVIGITQSLALELARHNIT- 181 Query: 585 VRCLVVCPGLTDS 623 CPG+ +S Sbjct: 182 --VNAFCPGIIES 192 >UniRef50_Q1ARM4 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Rubrobacter xylanophilus DSM 9941|Rep: Short-chain dehydrogenase/reductase SDR - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 252 Score = 81.8 bits (193), Expect = 2e-14 Identities = 59/191 (30%), Positives = 92/191 (48%), Gaps = 5/191 (2%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 L+GKVALITG A+GIG A + ++GA V + DI+ E + E + + G + F R Sbjct: 4 LEGKVALITGGATGIGRATALLFAREGACVLIGDINEEGASETVEAVRAAGG--DAAFRR 61 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDR----LWELEVDVNLNGVIRGTLLA 413 DV+ + EE+ R+D+V NAG + R L E +++L + L Sbjct: 62 CDVSGEEEIAALVAAAGEEYGRLDVVFGNAGLLRTRPLEDLSTKEFELHLRINLTANFLL 121 Query: 414 YRFMGK-DRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTGVR 590 ++ R +GG I+ AS R + Y A+ +V +TR+ D+ + V Sbjct: 122 TKYAAPVMRRHEGGSIIFMASAGGLRGTRGSVAYNASKGGLVNMTRSLADELAPHNIRVN 181 Query: 591 CLVVCPGLTDS 623 C VCPG D+ Sbjct: 182 C--VCPGWVDT 190 >UniRef50_Q11C03 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Mesorhizobium sp. BNC1|Rep: Short-chain dehydrogenase/reductase SDR - Mesorhizobium sp. (strain BNC1) Length = 257 Score = 81.8 bits (193), Expect = 2e-14 Identities = 57/214 (26%), Positives = 100/214 (46%), Gaps = 9/214 (4%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 L GKVAL+TGAA G+G A + EL QGA+V+L D+ E G +V E + G N + Sbjct: 4 LSGKVALVTGAARGLGEAIAVELAAQGARVALLDVLDELGAEVAENIKKSSG--NAYYRN 61 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF---------MNDRLWELEVDVNLNGVIR 398 D+ D + A + ++D+++NNA +++ W +VN++ + R Sbjct: 62 CDIRDTEEVRSAVDEVYSTYGKLDVLVNNAAVSTAPTSIPELSEETWNNIFNVNVSSIYR 121 Query: 399 GTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNV 578 M ++ G GG ++N +S + Y AT AI+ ++R ++ Sbjct: 122 FCRFVLPRM-QEAG--GGAVINMSSVHQSHSLTGWTAYAATKGAIISMSRQLAAEW--GR 176 Query: 579 TGVRCLVVCPGLTDSGLVXDLDKQLMSSKYETAW 680 +R V PG D+ + + + + + E A+ Sbjct: 177 FNIRVNTVSPGAIDATMTRQILDRDPTGRQEAAF 210 >UniRef50_A7IMM1 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Xanthobacter autotrophicus Py2|Rep: Short-chain dehydrogenase/reductase SDR precursor - Xanthobacter sp. (strain Py2) Length = 261 Score = 81.8 bits (193), Expect = 2e-14 Identities = 64/212 (30%), Positives = 95/212 (44%), Gaps = 8/212 (3%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFCR 245 LK K +ITGAA GIG A ++ L GA++++ D+ V ++ + G + Sbjct: 4 LKDKSIVITGAAGGIGAAIAKALAADGARITVADLSEPAARAVAGEITAAGG--TAIAVA 61 Query: 246 LDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRL--------WELEVDVNLNGVIRG 401 +DV Q V R+D++ NNAG R W DVN GV+ G Sbjct: 62 VDVRQRAQVRALLDEAVAAHGRLDVLFNNAGVAQTRPFLDITEDDWRFVTDVNALGVLIG 121 Query: 402 TLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVT 581 A + K +GG GG IVNTAS A + Y A+ +A+V LT+A + + Sbjct: 122 MQEAIKTF-KRQGG-GGKIVNTASIAAKQGYEPLAHYCASKFAVVALTQAAARAFGKDQI 179 Query: 582 GVRCLVVCPGLTDSGLVXDLDKQLMSSKYETA 677 V CPG+ + + +DK S +A Sbjct: 180 TVNAF--CPGVVATDMWKIIDKGFRDSGLTSA 209 >UniRef50_A7IEE4 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Xanthobacter autotrophicus Py2|Rep: Short-chain dehydrogenase/reductase SDR - Xanthobacter sp. (strain Py2) Length = 255 Score = 81.8 bits (193), Expect = 2e-14 Identities = 69/194 (35%), Positives = 87/194 (44%), Gaps = 10/194 (5%) Frame = +3 Query: 57 NMDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVL 236 ++DL GKVAL+TGAASGIGLA ++ L +QGA V L D D E + L + R + Sbjct: 4 DLDLSGKVALVTGAASGIGLAAAQLLARQGAHVVLADRDGAAAEAAAQALGAAGMRASSQ 63 Query: 237 FCRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF-----MNDRL---WELEVDVNLNGV 392 DVTD E + R+DI++NNAG + D WE VN+ G Sbjct: 64 --AFDVTDEAAVGEGVAQVLAALGRVDILVNNAGLSIRKGIADLALSDWEKVFAVNVTGA 121 Query: 393 IRGTLLAYRFMGKDRGGQGGVIVNTAST--AFARPQVSTPIYTATNYAIVGLTRAYGDQY 566 T M R G IVN AS P Y A+ AIV LTR G Sbjct: 122 FLTTRAVVPAM---RAQGAGAIVNIASIMGLSGGGPYPNPAYQASKGAIVNLTR--GLAV 176 Query: 567 HVNVTGVRCLVVCP 608 + G+R V P Sbjct: 177 ELAPAGIRVNAVAP 190 >UniRef50_A5WHV5 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Psychrobacter sp. PRwf-1|Rep: Short-chain dehydrogenase/reductase SDR - Psychrobacter sp. PRwf-1 Length = 273 Score = 81.8 bits (193), Expect = 2e-14 Identities = 68/223 (30%), Positives = 107/223 (47%), Gaps = 17/223 (7%) Frame = +3 Query: 84 LITGAASGIGLAYSEELLK-QGAKVSLCDIDSERGEQV--TEKLASKYGRKNVLFCRLDV 254 ++TGAASGIG A E LL +G +V CDI+ E Q+ KLA G +++ +LDV Sbjct: 6 IVTGAASGIGRALCERLLTDKGNQVCACDINYEALTQIYANHKLADAGG--SLILRQLDV 63 Query: 255 TDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRLW----------ELEVDVNLNGVIRGT 404 D Q++E + ++ RID++ N AG + D W +L D+N+ G I GT Sbjct: 64 RDVQQWQEVVNTVIAQWQRIDVMCNIAGVLKDN-WIADIALPDDVDLHFDINVKGTIFGT 122 Query: 405 LLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNVTG 584 M R G I+N AS A P +Y+A+ YA+ + A G + G Sbjct: 123 QSVVDTM---RNQGSGHIINVASLAALSPVPGLSLYSASKYAVRAYSLAAG--MELEKYG 177 Query: 585 VRCLVVCPGLTDSGLV-XDLDKQ---LMSSKYETAWLEDITDS 701 + +CP + ++ DK+ L S T ++++ D+ Sbjct: 178 IAVTTLCPDAVQTPMLDQQKDKEQAALTFSGSRTLTVDEVVDA 220 >UniRef50_A5GRS5 Cluster: 3-oxoacyl-[acyl-carrier-protein] reductase; n=16; cellular organisms|Rep: 3-oxoacyl-[acyl-carrier-protein] reductase - Synechococcus sp. (strain RCC307) Length = 250 Score = 81.8 bits (193), Expect = 2e-14 Identities = 60/201 (29%), Positives = 95/201 (47%), Gaps = 9/201 (4%) Frame = +3 Query: 66 LKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDS-ERGEQVTEKLASKYGRKNVLFC 242 L G++AL+TGA+ GIG A + +L + GA+V + S + EQV + + G L Sbjct: 7 LAGQIALVTGASRGIGRAIALQLAEAGAEVVVNYASSADAAEQVVSAITAAGGSAYAL-- 64 Query: 243 RLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRL--------WELEVDVNLNGVIR 398 + DV+ Q E+ +E+ RID++INNAG D L W+ +D+NL+GV Sbjct: 65 KADVSQEDQVEQLMAAVLEKSGRIDVLINNAGITRDGLLMRMKTPDWQAVLDLNLSGVFL 124 Query: 399 GTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNV 578 T R M K + G+ I+N S Y A ++G T++ + + Sbjct: 125 CTRAVTRTMLKQKQGR---IINITSVVGLMGNAGQANYAAAKAGVIGFTKSTARE--LAS 179 Query: 579 TGVRCLVVCPGLTDSGLVXDL 641 G+ V PG + + DL Sbjct: 180 RGITVNAVAPGFIATDMTKDL 200 >UniRef50_A5FRC2 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Dehalococcoides|Rep: Short-chain dehydrogenase/reductase SDR - Dehalococcoides sp. BAV1 Length = 265 Score = 81.8 bits (193), Expect = 2e-14 Identities = 53/191 (27%), Positives = 98/191 (51%), Gaps = 8/191 (4%) Frame = +3 Query: 63 DLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNVLFC 242 DL+GKVA++TG A GIG S L + GA + + D++ E ++ ++ + G+ + Sbjct: 9 DLRGKVAIVTGGAMGIGKGISMRLAEAGASIMIPDLNLEVAQKTVAEIKALGGKATAI-- 66 Query: 243 RLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGF--------MNDRLWELEVDVNLNGVIR 398 + DV++ ++ T++ F +DI++NNAG M + +W+ + +NL G++ Sbjct: 67 QADVSNINDTQKVIDATLKAFGDLDIMVNNAGIYRFMPAIDMTEAMWDKTLGINLKGLMF 126 Query: 399 GTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYHVNV 578 + A + M + GG I+N AS RP + Y A+ ++ LT+A ++ + Sbjct: 127 FSQAAAKAMMAAK--HGGKIINIASIDGFRPTGNLAHYDASKGGVIMLTKAMAQEWAPH- 183 Query: 579 TGVRCLVVCPG 611 G+ V PG Sbjct: 184 -GILVNAVAPG 193 >UniRef50_A0PSE4 Cluster: Short-chain type dehydrogenase; n=12; Corynebacterineae|Rep: Short-chain type dehydrogenase - Mycobacterium ulcerans (strain Agy99) Length = 285 Score = 81.8 bits (193), Expect = 2e-14 Identities = 73/241 (30%), Positives = 118/241 (48%), Gaps = 8/241 (3%) Frame = +3 Query: 48 SSINMDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRK 227 ++I + ++ KV +ITG A GIGLA + L K GAKV++ D+ GE ++ + G + Sbjct: 5 TTIGVRVRNKVIVITGGARGIGLATATALHKLGAKVAIGDV----GEPAVKEAGADLGLE 60 Query: 228 NVLFCRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFM--------NDRLWELEVDVNL 383 ++ +LDVTD F + + +D+++NNAG M D + +D+N+ Sbjct: 61 --VYGKLDVTDPNSFSDFLDQVERQLGPLDVLVNNAGIMPVGRIVDEPDSVTRRILDINV 118 Query: 384 NGVIRGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQ 563 GV+ G+ LA + M RG G ++N AS A V Y A+ +A++ T A + Sbjct: 119 YGVMVGSKLAAQRM-VPRG--RGHVINVASLAGEIYVVGLATYCASKHAVIAFTDAARIE 175 Query: 564 YHVNVTGVRCLVVCPGLTDSGLVXDLDKQLMSSKYETAWLEDITDSKCRALITLGKPLVD 743 Y TGV+ +V P ++ L ++ A DI D+ AL+ KP V Sbjct: 176 Y--RTTGVKFSMVLPTFVNTELASGTPGM---KGFKNAEPSDIADA-IVALVANPKPRVR 229 Query: 744 V 746 V Sbjct: 230 V 230 >UniRef50_Q0D3V4 Cluster: Os07g0664000 protein; n=34; cellular organisms|Rep: Os07g0664000 protein - Oryza sativa subsp. japonica (Rice) Length = 572 Score = 81.8 bits (193), Expect = 2e-14 Identities = 61/203 (30%), Positives = 95/203 (46%), Gaps = 8/203 (3%) Frame = +3 Query: 48 SSINMDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRK 227 SS + L GKVA+ITG ASGIG A + E +K GAKV + DI + G V +L Sbjct: 305 SSSHQRLAGKVAVITGGASGIGKATATEFIKNGAKVIIADIQDDLGHSVAAELG-----P 359 Query: 228 NVLFCRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRLWELEVDVNLNGV----- 392 + + R DV D Q A + V+ R+D+ NNAG + V+L Sbjct: 360 DAAYTRCDVADEAQVAAAVGLAVKRHGRLDVFHNNAGIAGALPQDDMAAVDLGDFDRVMA 419 Query: 393 --IRGTLLAYRFMGKDRGGQ-GGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQ 563 R TL A + + + G ++ T+S A P + P+Y+ + ++ + RA + Sbjct: 420 VNARSTLAAVKHAARAMAPRCSGCVLCTSSGAGVIPVPAVPVYSVSKATVIAIVRAAAEP 479 Query: 564 YHVNVTGVRCLVVCPGLTDSGLV 632 + G+R + PG T + L+ Sbjct: 480 MARH--GLRVNAISPGATRTPLL 500 >UniRef50_Q9Z8P2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reductase; n=26; Bacteria|Rep: 3-oxoacyl-[acyl-carrier-protein] reductase - Chlamydia pneumoniae (Chlamydophila pneumoniae) Length = 248 Score = 81.8 bits (193), Expect = 2e-14 Identities = 61/221 (27%), Positives = 97/221 (43%), Gaps = 8/221 (3%) Frame = +3 Query: 54 INMDLKGKVALITGAASGIGLAYSEELLKQGAKVSLCDIDSERGEQVTEKLASKYGRKNV 233 +++ L GK ++TG + GIGL + L+ GA V + ++ ERG+ V E L G V Sbjct: 1 MDITLVGKKVIVTGGSRGIGLGIVKLFLENGADVEIWGLNEERGQAVIESLTGLGG--EV 58 Query: 234 LFCRLDVTDYPQFEEAFVMTVEEFNRIDIVINNAGFMNDRL--------WELEVDVNLNG 389 F R+DV+ ++ +++ N+IDI++NNAG D L W+ + NL Sbjct: 59 SFARVDVSHNGGVKDCVQKFLDKHNKIDILVNNAGITRDNLLMRMSEDDWQSVISTNLTS 118 Query: 390 VIRGTLLAYRFMGKDRGGQGGVIVNTASTAFARPQVSTPIYTATNYAIVGLTRAYGDQYH 569 + R M K R G I+N AS Y A I+ T++ + Sbjct: 119 LYYTCSSVIRHMIKARSGS---IINVASIVAKIGSAGQTNYAAAKAGIIAFTKSLAKEVA 175 Query: 570 VNVTGVRCLVVCPGLTDSGLVXDLDKQLMSSKYETAWLEDI 692 V CL PG ++ + L+ L + WL+ I Sbjct: 176 ARNIRVNCL--APGFIETDMTSVLNDNL-----KAEWLKSI 209 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 742,278,430 Number of Sequences: 1657284 Number of extensions: 15136332 Number of successful extensions: 53876 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 47897 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 50287 length of database: 575,637,011 effective HSP length: 99 effective length of database: 411,565,895 effective search space used: 61734884250 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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