BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= brP-0019 (800 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_Q13630 Cluster: GDP-L-fucose synthetase (EC 1.1.1.271) ... 256 4e-67 UniRef50_A5PHP4 Cluster: GDP-4-dehydro-6-deoxy-D-mannose epimera... 232 7e-60 UniRef50_Q00XZ4 Cluster: GDP-4-keto-6-deoxy-D-mannose epimerase-... 201 1e-50 UniRef50_Q8IJQ5 Cluster: GDP-fucose synthase, putative; n=5; Pla... 157 2e-37 UniRef50_Q74FI1 Cluster: GDP-fucose synthetase; n=7; Bacteria|Re... 127 3e-28 UniRef50_Q0BHR7 Cluster: NAD-dependent epimerase/dehydratase; n=... 120 6e-26 UniRef50_Q2IZX2 Cluster: NAD-dependent epimerase/dehydratase; n=... 119 1e-25 UniRef50_Q4AI76 Cluster: GDP-L-fucose synthase; n=6; Bacteria|Re... 118 2e-25 UniRef50_Q0EXY2 Cluster: GDP-fucose synthetase; n=4; Proteobacte... 117 3e-25 UniRef50_Q0M6J4 Cluster: NAD-dependent epimerase/dehydratase:3-b... 113 4e-24 UniRef50_Q3B1R9 Cluster: GDP-L-fucose synthetase; n=3; Bacteria|... 112 1e-23 UniRef50_Q2RXT6 Cluster: NAD-dependent epimerase/dehydratase; n=... 112 1e-23 UniRef50_Q7BR89 Cluster: GDP-6-deoxy-4-keto-D-mannose-3, 5-epime... 111 2e-23 UniRef50_A7IWS0 Cluster: Putative uncharacterized protein B395L;... 110 3e-23 UniRef50_Q124Z8 Cluster: NAD-dependent epimerase/dehydratase; n=... 110 3e-23 UniRef50_A5ZJL9 Cluster: Putative uncharacterized protein; n=1; ... 110 3e-23 UniRef50_Q8VU14 Cluster: GDP-4-keto-6-deoxy-D-mannose-3, 5-epime... 110 5e-23 UniRef50_Q93N55 Cluster: GDP-4-keto-6 deoxymannose epimerase/red... 109 6e-23 UniRef50_A6VG32 Cluster: NAD-dependent epimerase/dehydratase; n=... 109 6e-23 UniRef50_A4YQ54 Cluster: Bifunctional GDP-fucose synthetase: GDP... 108 1e-22 UniRef50_Q5V3C6 Cluster: DTDP-glucose dehydratase; n=23; cellula... 108 1e-22 UniRef50_Q9XDD7 Cluster: Bme10; n=1; Brucella melitensis|Rep: Bm... 107 4e-22 UniRef50_Q1VHC4 Cluster: GDP-fucose synthetase chain A; n=1; Psy... 105 2e-21 UniRef50_O49213 Cluster: GDP-L-fucose synthase 1; n=181; root|Re... 105 2e-21 UniRef50_Q7MV22 Cluster: GDP-fucose synthetase; n=5; Bacteria|Re... 104 3e-21 UniRef50_A2BXU6 Cluster: Putative fucose synthetase; n=1; Prochl... 100 9e-20 UniRef50_Q8L2G9 Cluster: Fcl; n=2; Enterobacteriaceae|Rep: Fcl -... 99 1e-19 UniRef50_O84974 Cluster: O-antigen biosynthesis protein; n=5; He... 99 1e-19 UniRef50_A1B1K8 Cluster: NAD-dependent epimerase/dehydratase; n=... 98 3e-19 UniRef50_A5GHX4 Cluster: GDP-L fucose synthetase; n=25; Bacteria... 97 6e-19 UniRef50_Q9AQ09 Cluster: Putative nodulation NAD-dependent nucle... 92 1e-17 UniRef50_Q8VQ41 Cluster: WbdJ; n=13; Bacteria|Rep: WbdJ - Escher... 92 2e-17 UniRef50_P33217 Cluster: Nodulation protein nolK; n=2; Alphaprot... 90 7e-17 UniRef50_Q2BI22 Cluster: DTDP-glucose dehydratase; n=1; Neptunii... 87 4e-16 UniRef50_Q67WR5 Cluster: Putative GDP-L-fucose synthase 2; n=4; ... 85 2e-15 UniRef50_A0R4U4 Cluster: NAD dependent epimerase/dehydratase fam... 74 5e-12 UniRef50_Q30CR4 Cluster: LipDig4; n=3; Streptomyces|Rep: LipDig4... 61 3e-08 UniRef50_Q1J353 Cluster: GDP-L-fucose synthase; n=1; Deinococcus... 61 3e-08 UniRef50_Q18EM2 Cluster: Nucleoside-diphosphate-sugar epimerase;... 60 8e-08 UniRef50_A6GLY7 Cluster: Putative uncharacterized protein; n=1; ... 57 4e-07 UniRef50_Q5SKQ2 Cluster: UDP-glucose 4-epimerase; n=4; Thermus|R... 56 8e-07 UniRef50_Q83DA9 Cluster: NAD dependent epimerase/dehydratase fam... 54 4e-06 UniRef50_Q1GN57 Cluster: NAD-dependent epimerase/dehydratase; n=... 54 6e-06 UniRef50_Q55412 Cluster: Slr0583 protein; n=3; Chroococcales|Rep... 53 7e-06 UniRef50_A5GEL7 Cluster: NAD-dependent epimerase/dehydratase pre... 53 1e-05 UniRef50_Q2NIA3 Cluster: Putative UDP-glucose 4-epimerase; n=1; ... 53 1e-05 UniRef50_Q9ZHQ3 Cluster: 4-ketoreductase; n=2; Actinomycetales|R... 50 5e-05 UniRef50_Q9K7I2 Cluster: UDP-glucose 4-epimerase; n=17; cellular... 50 7e-05 UniRef50_A5GIA6 Cluster: NAD dependent epimerase/dehydratase; n=... 50 9e-05 UniRef50_Q12VP0 Cluster: NAD-dependent epimerase/dehydratase; n=... 49 1e-04 UniRef50_Q8DJM2 Cluster: Nucleotide sugar epimerase; n=61; cellu... 48 2e-04 UniRef50_Q5KWG9 Cluster: Nucleotide sugar epimerase; n=1; Geobac... 48 2e-04 UniRef50_O06485 Cluster: YfnG; n=3; Bacteria|Rep: YfnG - Bacillu... 48 2e-04 UniRef50_Q5KUQ5 Cluster: UDP-glucose 4-epimerase; n=5; Bacteria|... 48 4e-04 UniRef50_A5WE41 Cluster: NAD-dependent epimerase/dehydratase; n=... 48 4e-04 UniRef50_A0L5P6 Cluster: UDP-glucose 4-epimerase; n=4; Bacteria|... 48 4e-04 UniRef50_A1SL10 Cluster: NAD-dependent epimerase/dehydratase; n=... 47 6e-04 UniRef50_A2SRX5 Cluster: NAD-dependent epimerase/dehydratase; n=... 47 6e-04 UniRef50_Q9FB21 Cluster: Sugar epimerase BlmG; n=1; Streptomyces... 46 0.001 UniRef50_A5UK04 Cluster: UDP-glucose 4-epimerase; n=2; Euryarcha... 46 0.001 UniRef50_Q0W7F9 Cluster: Putative UDP-glucose 4-epimerase; n=1; ... 46 0.001 UniRef50_Q9ABX8 Cluster: UDP-glucose 4-epimerase; n=1; Caulobact... 45 0.002 UniRef50_Q70PA0 Cluster: Putative uncharacterized protein; n=1; ... 45 0.002 UniRef50_Q9KDV3 Cluster: UDP-glucose 4-epimerase; n=124; cellula... 45 0.002 UniRef50_Q832Q5 Cluster: NAD-dependent epimerase/dehydratase fam... 45 0.003 UniRef50_O54385 Cluster: UDP-glucose epimerase; n=11; cellular o... 45 0.003 UniRef50_A6CLM3 Cluster: UDP-glucose 4-epimerase; n=1; Bacillus ... 45 0.003 UniRef50_O28263 Cluster: UDP-glucose 4-epimerase; n=1; Archaeogl... 45 0.003 UniRef50_A3ERU6 Cluster: Nucleoside-diphosphate-sugar epimerase;... 44 0.003 UniRef50_Q8R8R8 Cluster: UDP-glucose 4-epimerase; n=15; Bacteria... 44 0.004 UniRef50_Q83W21 Cluster: Ata17 protein; n=9; Bacteria|Rep: Ata17... 44 0.004 UniRef50_Q9WYX9 Cluster: UDP-glucose 4-epimerase, putative; n=5;... 44 0.006 UniRef50_Q0C2X5 Cluster: UDP-glucose 4-epimerase; n=1; Hyphomona... 44 0.006 UniRef50_A7HI28 Cluster: NAD-dependent epimerase/dehydratase; n=... 44 0.006 UniRef50_Q8TXF0 Cluster: Nucleoside-diphosphate-sugar epimerase;... 44 0.006 UniRef50_Q8THP9 Cluster: DTDP-glucose 4,6-dehydratase; n=3; Meth... 43 0.008 UniRef50_Q9RWF7 Cluster: UDP-glucose 4-epimerase, putative; n=63... 43 0.010 UniRef50_Q6MF46 Cluster: Probable UDP-glucuronat epimerase; n=2;... 43 0.010 UniRef50_Q9JRN7 Cluster: Putative uncharacterized protein; n=1; ... 43 0.010 UniRef50_A3PE63 Cluster: UDP-glucose 4-epimerase; n=1; Prochloro... 43 0.010 UniRef50_Q9YCT1 Cluster: DTDP-glucose 4,6-dehydratase; n=2; Ther... 43 0.010 UniRef50_A7CY79 Cluster: NAD-dependent epimerase/dehydratase; n=... 42 0.014 UniRef50_Q2SII8 Cluster: Nucleoside-diphosphate-sugar epimerase;... 42 0.018 UniRef50_Q12UG3 Cluster: NAD-dependent epimerase/dehydratase; n=... 42 0.018 UniRef50_Q661H6 Cluster: Nucleotide sugar epimerase; n=3; Borrel... 42 0.024 UniRef50_Q0YI68 Cluster: NAD-dependent epimerase/dehydratase:Sho... 42 0.024 UniRef50_Q5FQW6 Cluster: UDP-glucose 4-epimerase; n=3; Bacteria|... 41 0.032 UniRef50_A6PV21 Cluster: UDP-glucose 4-epimerase; n=1; Victivall... 41 0.032 UniRef50_A0B5G2 Cluster: NAD-dependent epimerase/dehydratase; n=... 41 0.032 UniRef50_Q9LIS3 Cluster: UDP-glucuronate 4-epimerase 6; n=40; Vi... 41 0.032 UniRef50_P72903 Cluster: UDP-glucose-4-epimerase; n=20; Bacteria... 41 0.042 UniRef50_Q1VUQ5 Cluster: Sugar epimerase BlmG; n=2; Bacteria|Rep... 41 0.042 UniRef50_A4CBV8 Cluster: NAD dependent epimerase/dehydratase fam... 40 0.055 UniRef50_O26473 Cluster: DTDP-glucose 4,6-dehydratase related pr... 40 0.055 UniRef50_A7DQX9 Cluster: NAD-dependent epimerase/dehydratase; n=... 40 0.055 UniRef50_Q5FRS4 Cluster: UDP-N-acetylglucosamine 4-epimerase; n=... 40 0.073 UniRef50_Q1VGF9 Cluster: Putative uncharacterized protein; n=1; ... 40 0.073 UniRef50_Q0LJ11 Cluster: NAD-dependent epimerase/dehydratase; n=... 40 0.073 UniRef50_A7GZ40 Cluster: dTDP-glucose 4,6-dehydratase; n=1; Camp... 40 0.073 UniRef50_Q81AP5 Cluster: CDP-abequose synthase; n=2; Bacillus ce... 40 0.096 UniRef50_Q3ESA4 Cluster: DTDP-glucose 4,6-dehydratase; n=3; Firm... 40 0.096 UniRef50_A6DF55 Cluster: Putative uncharacterized protein; n=1; ... 40 0.096 UniRef50_A5M424 Cluster: UDP-glucose 4-epimerase; n=1; Streptoco... 40 0.096 UniRef50_Q18EM3 Cluster: Nucleoside-diphosphate-sugar epimerase;... 39 0.13 UniRef50_Q1YMT2 Cluster: UDP-glucose 4-epimerase; n=3; Alphaprot... 39 0.17 UniRef50_Q93VR3 Cluster: GDP-mannose 3,5-epimerase; n=21; cellul... 39 0.17 UniRef50_Q42605 Cluster: UDP-glucose 4-epimerase; n=20; Viridipl... 39 0.17 UniRef50_UPI0000DAE763 Cluster: hypothetical protein Rgryl_01001... 38 0.22 UniRef50_Q9RSC3 Cluster: UDP-glucose 4-epimerase; n=1; Deinococc... 38 0.22 UniRef50_Q65E95 Cluster: Putative uncharacterized protein; n=1; ... 38 0.22 UniRef50_Q2WB63 Cluster: Nucleoside-diphosphate-sugar epimerase;... 38 0.22 UniRef50_Q8GP51 Cluster: Eps11G; n=11; Bacteria|Rep: Eps11G - St... 38 0.22 UniRef50_Q7D561 Cluster: NAD-dependent epimerase/dehydratase fam... 38 0.22 UniRef50_Q4HQ86 Cluster: UDP-glucose 4-epimerase, putative; n=2;... 38 0.22 UniRef50_Q7WNH4 Cluster: Putative NAD dependent epimerase/dehydr... 38 0.29 UniRef50_Q1FJC1 Cluster: DTDP-glucose 4,6-dehydratase; n=1; Clos... 38 0.29 UniRef50_Q11WU7 Cluster: UDP-galactose-4-epimerase; n=1; Cytopha... 38 0.29 UniRef50_A1GFD2 Cluster: NAD-dependent epimerase/dehydratase; n=... 38 0.29 UniRef50_Q5UXR0 Cluster: UDP-glucose 4-epimerase; n=3; Halobacte... 38 0.29 UniRef50_A6GG02 Cluster: Putative uncharacterized protein; n=1; ... 38 0.39 UniRef50_Q8WUS8 Cluster: HSPC105 protein; n=21; Euteleostomi|Rep... 38 0.39 UniRef50_Q2FS05 Cluster: NAD-dependent epimerase/dehydratase; n=... 38 0.39 UniRef50_Q982P5 Cluster: UDP-glucose 4-epimerase; n=1; Mesorhizo... 37 0.51 UniRef50_Q8ECF4 Cluster: DTDP-glucose 4,6-dehydratase; n=18; Gam... 37 0.51 UniRef50_Q1QD53 Cluster: NAD-dependent epimerase/dehydratase; n=... 37 0.51 UniRef50_Q0BRM8 Cluster: UDP-glucose 4-epimerase; n=2; Rhodospir... 37 0.51 UniRef50_A6GE58 Cluster: NAD-dependent epimerase/dehydratase fam... 37 0.51 UniRef50_A4QBQ0 Cluster: Putative uncharacterized protein; n=1; ... 37 0.51 UniRef50_Q57664 Cluster: Putative UDP-glucose 4-epimerase; n=3; ... 37 0.51 UniRef50_Q7UXZ2 Cluster: 3-beta-hydroxysteroid dehydrogenase; n=... 37 0.68 UniRef50_A6Q4T4 Cluster: NAD-dependent epimerase/dehydratase; n=... 37 0.68 UniRef50_A3ERM8 Cluster: UDP-glucose 4-epimerase; n=1; Leptospir... 37 0.68 UniRef50_A6SIX9 Cluster: Putative uncharacterized protein; n=1; ... 37 0.68 UniRef50_Q5V6W4 Cluster: UDP-glucose 4-epimerase; n=1; Haloarcul... 37 0.68 UniRef50_Q65D61 Cluster: Putative uncharacterized protein; n=1; ... 36 0.90 UniRef50_A3Q712 Cluster: UDP-glucose 4-epimerase; n=6; Actinobac... 36 0.90 UniRef50_Q2FKD1 Cluster: NAD-dependent epimerase/dehydratase fam... 36 1.2 UniRef50_Q1GKR7 Cluster: UDP-glucose 4-epimerase; n=17; Bacteria... 36 1.2 UniRef50_P14169 Cluster: CDP-paratose 2-epimerase; n=12; cellula... 36 1.2 UniRef50_UPI0001597850 Cluster: hypothetical protein RBAM_031220... 36 1.6 UniRef50_Q97KX2 Cluster: Nucleoside-diphosphate-sugar epimerase;... 36 1.6 UniRef50_Q8RGC6 Cluster: UDP-glucose 4-epimerase; n=2; Fusobacte... 36 1.6 UniRef50_A7DIX5 Cluster: NAD-dependent epimerase/dehydratase; n=... 36 1.6 UniRef50_A6PTX1 Cluster: NAD-dependent epimerase/dehydratase; n=... 36 1.6 UniRef50_A6BZU3 Cluster: Putative uncharacterized protein; n=1; ... 36 1.6 UniRef50_A3H6D1 Cluster: NAD-dependent epimerase/dehydratase; n=... 36 1.6 UniRef50_Q8KNN2 Cluster: DTDP-D-glucose-4,6-dehydratase; n=4; Ba... 35 2.1 UniRef50_A7HN54 Cluster: Polysaccharide biosynthesis protein Cap... 35 2.1 UniRef50_A6CEQ2 Cluster: Putative uncharacterized protein; n=1; ... 35 2.7 UniRef50_A0LGE9 Cluster: NAD-dependent epimerase/dehydratase; n=... 35 2.7 UniRef50_Q8ZW82 Cluster: UDP-glucose 4-epimerase; n=6; Thermopro... 35 2.7 UniRef50_P18645 Cluster: UDP-glucose 4-epimerase; n=353; cellula... 35 2.7 UniRef50_Q7CS52 Cluster: AGR_L_3011p; n=3; Alphaproteobacteria|R... 34 3.6 UniRef50_Q1YQ08 Cluster: Oxidoreductase; n=1; gamma proteobacter... 34 3.6 UniRef50_A7I3Y2 Cluster: Putative zinc protease; n=1; Campylobac... 34 3.6 UniRef50_A4BBD6 Cluster: Putative uncharacterized protein; n=1; ... 34 3.6 UniRef50_A1IBU5 Cluster: Nucleoside-diphosphate-sugar epimerases... 34 3.6 UniRef50_Q868I5 Cluster: UDP-N-acetylglucosamine 4-epimerase; n=... 34 3.6 UniRef50_Q54WS6 Cluster: Putative dTDP-D-glucose 4,6-dehydratase... 34 3.6 UniRef50_A0BCG5 Cluster: Chromosome undetermined scaffold_10, wh... 34 3.6 UniRef50_A3LR65 Cluster: Putative dtdp-glucose 4,6-dehydratase; ... 34 3.6 UniRef50_Q59083 Cluster: UDP-glucose 4-epimerase; n=14; Bacteria... 34 3.6 UniRef50_Q2JCE7 Cluster: DTDP-glucose 4,6-dehydratase; n=5; Bact... 34 4.8 UniRef50_Q01T66 Cluster: DTDP-glucose 4,6-dehydratase precursor;... 34 4.8 UniRef50_A7HHX8 Cluster: NAD-dependent epimerase/dehydratase; n=... 34 4.8 UniRef50_A6H035 Cluster: GDP-4-dehydro-D-rhamnose reductase; n=1... 34 4.8 UniRef50_A3DIS0 Cluster: Polysaccharide biosynthesis protein Cap... 34 4.8 UniRef50_A3CKR6 Cluster: Nucleoside-diphosphate-sugar epimerase,... 34 4.8 UniRef50_A0UVI4 Cluster: NAD-dependent epimerase/dehydratase; n=... 34 4.8 UniRef50_A0L9M4 Cluster: NAD-dependent epimerase/dehydratase; n=... 34 4.8 UniRef50_Q5DAK3 Cluster: SJCHGC01535 protein; n=2; Schistosoma j... 34 4.8 UniRef50_Q814Z6 Cluster: UDP-N-acetylglucosamine 4-epimerase; n=... 33 6.3 UniRef50_Q7VRZ4 Cluster: Thymidine diphosphoglucose 4,6-dehydrat... 33 6.3 UniRef50_Q1MP11 Cluster: Nucleoside-diphosphate-sugar epimerases... 33 6.3 UniRef50_A5N5N5 Cluster: Predicted nucleoside-diphosphate-sugar ... 33 6.3 UniRef50_A3ZSY0 Cluster: CDP glucose 4,6-dehydratase; n=1; Blast... 33 6.3 UniRef50_Q9HSU9 Cluster: GDP-D-mannose dehydratase; n=2; Halobac... 33 6.3 UniRef50_A4FIG8 Cluster: Modular polyketide synthase; n=1; Sacch... 33 8.4 UniRef50_Q2U1I6 Cluster: Polyketide synthase modules and related... 33 8.4 UniRef50_A5DWB0 Cluster: Putative uncharacterized protein; n=2; ... 33 8.4 UniRef50_A2R6J0 Cluster: Catalytic activity: dTDPglucose = dTDP-... 33 8.4 UniRef50_O95455 Cluster: dTDP-D-glucose 4,6-dehydratase; n=24; E... 33 8.4 >UniRef50_Q13630 Cluster: GDP-L-fucose synthetase (EC 1.1.1.271) (Protein FX) (Red cell NADP(H)- binding protein); n=59; Eukaryota|Rep: GDP-L-fucose synthetase (EC 1.1.1.271) (Protein FX) (Red cell NADP(H)- binding protein) - Homo sapiens (Human) Length = 321 Score = 256 bits (628), Expect = 4e-67 Identities = 111/167 (66%), Positives = 133/167 (79%) Frame = +2 Query: 194 ETWIFSGSKDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSIND 373 E W+F SKD DL D QT ALF K +PTHVIHLAAMVGGLF N+ +NLDF+R+N+ +ND Sbjct: 36 EDWVFVSSKDADLTDTAQTRALFEKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMND 95 Query: 374 NILQACHKYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNR 553 N+L + + +KVVSCLSTCIFPDKTTYPIDETM+HNGPPH+SNFGYSYAKRMIDV NR Sbjct: 96 NVLHSAFEVGARKVVSCLSTCIFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNR 155 Query: 554 GYNESYGCMFTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKG 694 Y + YGC FT+VIP NVFGPHDNF+++ HV+P LI ++ A G Sbjct: 156 AYFQQYGCTFTAVIPTNVFGPHDNFNIEDGHVLPGLIHKVHLAKSSG 202 Score = 41.9 bits (94), Expect = 0.018 Identities = 16/22 (72%), Positives = 18/22 (81%) Frame = +1 Query: 715 WGSGKPLRQFIYSLXLGELFIW 780 WG+G P RQFIYSL L +LFIW Sbjct: 208 WGTGNPRRQFIYSLDLAQLFIW 229 >UniRef50_A5PHP4 Cluster: GDP-4-dehydro-6-deoxy-D-mannose epimerase/reductase; n=2; Trypanosoma brucei|Rep: GDP-4-dehydro-6-deoxy-D-mannose epimerase/reductase - Trypanosoma brucei brucei Length = 358 Score = 232 bits (568), Expect = 7e-60 Identities = 103/177 (58%), Positives = 130/177 (73%) Frame = +2 Query: 170 KRNSDYDSETWIFSGSKDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFF 349 KRN+ D E W+F D DLR T +F +HKPTHV+HLAA VGGLF NMA ++ + Sbjct: 66 KRNACAD-ERWVFLSRHDADLRSMAATRCVFERHKPTHVLHLAARVGGLFKNMAAPVEMW 124 Query: 350 RENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAK 529 +N+SIN+N+L+ C Y V+K VSCLSTCIFP++ TYPI E +H+GPPH SN Y+YAK Sbjct: 125 IDNVSINNNVLECCRTYGVRKAVSCLSTCIFPERATYPIGEETLHDGPPHYSNEQYAYAK 184 Query: 530 RMIDVLNRGYNESYGCMFTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDP 700 RMIDVLNR YN+ YGC FTSVIP NV+GPHDN++L+ SHVIP LI + A ++ P Sbjct: 185 RMIDVLNRAYNKEYGCRFTSVIPTNVYGPHDNYNLQDSHVIPGLIHKFYLAKRENKP 241 Score = 35.9 bits (79), Expect = 1.2 Identities = 13/21 (61%), Positives = 17/21 (80%) Frame = +1 Query: 718 GSGKPLRQFIYSLXLGELFIW 780 G+G+PLRQF+YS L EL +W Sbjct: 246 GTGRPLRQFVYSEDLAELIVW 266 >UniRef50_Q00XZ4 Cluster: GDP-4-keto-6-deoxy-D-mannose epimerase-reductase; n=1; Ostreococcus tauri|Rep: GDP-4-keto-6-deoxy-D-mannose epimerase-reductase - Ostreococcus tauri Length = 252 Score = 201 bits (491), Expect = 1e-50 Identities = 105/197 (53%), Positives = 126/197 (63%), Gaps = 35/197 (17%) Frame = +2 Query: 215 SKDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMA--------------------- 331 S+D +L D T A+F K+KPTHVIHLAA VGGLF NM Sbjct: 14 SQDANLCDPESTAAMFDKYKPTHVIHLAAQVGGLFANMVRAKRRERSNRIATDIRAFVFP 73 Query: 332 ---HNLDFFRENMSINDNILQACHKYN-----------VKKVVSCLSTCIFPDKTTYPID 469 + ++F+R N+++NDNI Q CHK V+K+VSCLSTCIFPDKTT+PID Sbjct: 74 PQKYKVEFWRNNIAMNDNIFQECHKRGTLAWIAINITRVQKLVSCLSTCIFPDKTTFPID 133 Query: 470 ETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPHDNFSLKSSHV 649 ETM+HNGPPH SN GY+YAKRM+DV NR Y +GC FT+VIP N+FG HDNF L SHV Sbjct: 134 ETMIHNGPPHFSNEGYAYAKRMVDVQNRMYKAQHGCNFTAVIPTNIFGKHDNFHLDDSHV 193 Query: 650 IPALIRRMDDAMQKGDP 700 IP LI R QKG+P Sbjct: 194 IPGLIHRGYLCKQKGEP 210 Score = 42.3 bits (95), Expect = 0.014 Identities = 17/22 (77%), Positives = 17/22 (77%) Frame = +1 Query: 715 WGSGKPLRQFIYSLXLGELFIW 780 WGSGKPLRQFIYS L L IW Sbjct: 214 WGSGKPLRQFIYSTDLARLMIW 235 >UniRef50_Q8IJQ5 Cluster: GDP-fucose synthase, putative; n=5; Plasmodium|Rep: GDP-fucose synthase, putative - Plasmodium falciparum (isolate 3D7) Length = 329 Score = 157 bits (382), Expect = 2e-37 Identities = 73/181 (40%), Positives = 119/181 (65%), Gaps = 4/181 (2%) Frame = +2 Query: 143 KTVIERDRQ---KRNSDYDSET-WIFSGSKDGDLRDKTQTEALFAKHKPTHVIHLAAMVG 310 K +IE++ + N + + T +IF S+ DL+D +++ +F K+ T +IH AA VG Sbjct: 27 KNIIEKENEIIVNSNENKNIITKYIFLSSEMCDLKDYDKSKLVFEKYNFTDIIHFAAHVG 86 Query: 311 GLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTYPIDETMVHNG 490 GL+ N +NLDF N+ I+ N+++ CHKY++ + + LSTCIFP + P+ E +H+G Sbjct: 87 GLYANKNNNLDFLINNLEISMNVIKLCHKYSISRGIFTLSTCIFPVNCSLPLTEEKIHDG 146 Query: 491 PPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPHDNFSLKSSHVIPALIRR 670 H SN GYS +KR+++VL R Y E Y + +IP N++G +DNF+L+++HVIP++I + Sbjct: 147 KCHQSNEGYSVSKRVLEVLVRFYREKYNYEWICIIPTNIYGKYDNFNLENAHVIPSIIHK 206 Query: 671 M 673 M Sbjct: 207 M 207 >UniRef50_Q74FI1 Cluster: GDP-fucose synthetase; n=7; Bacteria|Rep: GDP-fucose synthetase - Geobacter sulfurreducens Length = 314 Score = 127 bits (307), Expect = 3e-28 Identities = 62/159 (38%), Positives = 91/159 (57%) Frame = +2 Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 406 DLRD+ A FA +P +V AA VGG+ N + +F +N+ I N++ + ++ V Sbjct: 41 DLRDQAAVAAFFAAEQPDYVFLAAAKVGGIVANNTYPAEFIYDNLMIEANVIHSSYRTGV 100 Query: 407 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 586 K++ STCI+P + PI E + GP +N Y+ AK L R YN YG F Sbjct: 101 SKLLFLGSTCIYPKMASQPIREEYLLTGPLEPTNEAYAIAKIAGISLCRSYNRQYGTRFI 160 Query: 587 SVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDPT 703 + +P N++GP+DNF L+ SHV+PALIR+ +A G PT Sbjct: 161 AAMPTNLYGPNDNFDLEKSHVLPALIRKFHEAKIAGAPT 199 >UniRef50_Q0BHR7 Cluster: NAD-dependent epimerase/dehydratase; n=1; Burkholderia ambifaria AMMD|Rep: NAD-dependent epimerase/dehydratase - Burkholderia cepacia (strain ATCC 53795 / AMMD) Length = 311 Score = 120 bits (288), Expect = 6e-26 Identities = 59/162 (36%), Positives = 91/162 (56%) Frame = +2 Query: 215 SKDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACH 394 S D DLRD++ TE +F + +PT V H+AA V G+ NM++ + +N+ IN N+++A Sbjct: 38 SSDIDLRDQSATEKMFDELRPTIVFHMAARVYGIMGNMSNRGIAYLDNVRINTNVVEAAR 97 Query: 395 KYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYG 574 + KK V+ ST I+ D+ P+ E + G PH S Y+++KR + Y + YG Sbjct: 98 QTGCKKFVAMGSTAIYSDQVRLPMSEEQIWVGAPHHSEAPYAHSKRGMLAQLEAYKDQYG 157 Query: 575 CMFTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDP 700 + + N+FGPHD F K HVIP+L+ + A G P Sbjct: 158 MDYAFCVSTNLFGPHDKFDEKFGHVIPSLVSKFYRASVLGQP 199 >UniRef50_Q2IZX2 Cluster: NAD-dependent epimerase/dehydratase; n=4; Alphaproteobacteria|Rep: NAD-dependent epimerase/dehydratase - Rhodopseudomonas palustris (strain HaA2) Length = 337 Score = 119 bits (286), Expect = 1e-25 Identities = 59/161 (36%), Positives = 90/161 (55%) Frame = +2 Query: 212 GSKDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQAC 391 G + DLR +T+ + F+ +P VI AA VGG+ N + F +N+SI DN++Q+ Sbjct: 41 GRDELDLRHQTKVQEWFSSERPDVVILAAARVGGVLANSKYPASFLSDNLSIQDNVIQSA 100 Query: 392 HKYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESY 571 VKK++ S+C++P + PI+E + G +N Y AK + Y E Y Sbjct: 101 AAAGVKKLLFVSSSCVYPRLASQPIEEDALLTGALEPTNRWYGVAKIAGMMQCAAYREQY 160 Query: 572 GCMFTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKG 694 GC F + +P N++GP D F ++SHVIPA +RR DA+ G Sbjct: 161 GCDFIAAVPGNLYGPGDYFDKENSHVIPAFLRRFHDAVTTG 201 >UniRef50_Q4AI76 Cluster: GDP-L-fucose synthase; n=6; Bacteria|Rep: GDP-L-fucose synthase - Chlorobium phaeobacteroides BS1 Length = 402 Score = 118 bits (283), Expect = 2e-25 Identities = 58/149 (38%), Positives = 87/149 (58%) Frame = +2 Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 406 DLR+ + F + KP +VI AA VGG+ N + DF EN+ I N++ + V Sbjct: 41 DLRNTMAVKTFFEREKPEYVILAAAKVGGIVANNTYRADFIYENLMIQSNVIHQSYLSGV 100 Query: 407 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 586 KK++ STCI+P + P+ E + P +N Y+ AK + YN YG F Sbjct: 101 KKLLFLGSTCIYPKECPQPMKEEHLLTSPLEYTNEPYAIAKIAGIKMCESYNIQYGTNFI 160 Query: 587 SVIPCNVFGPHDNFSLKSSHVIPALIRRM 673 SV+P N++GP+DNF+L++SHV+PALIR++ Sbjct: 161 SVMPTNLYGPNDNFNLETSHVLPALIRKI 189 >UniRef50_Q0EXY2 Cluster: GDP-fucose synthetase; n=4; Proteobacteria|Rep: GDP-fucose synthetase - Mariprofundus ferrooxydans PV-1 Length = 371 Score = 117 bits (282), Expect = 3e-25 Identities = 60/173 (34%), Positives = 98/173 (56%), Gaps = 2/173 (1%) Frame = +2 Query: 185 YDSETWIFSGSKDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMS 364 + E+ + S + DLR++ +A FA +P +V AA VGG++ N + DF R+N+ Sbjct: 43 HSPESLVLRTSSELDLRNQAAVDAFFALERPEYVFLAAAKVGGIYANDTYPADFIRDNLQ 102 Query: 365 INDNILQACHKYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDV 544 I N++ A + VK+++ S+CI+P P+ E+ + G +N Y+ AK Sbjct: 103 IQTNVIDAAYSNGVKRLLFLGSSCIYPKLAPQPMPESCLLTGELEPTNEWYAIAKIAGIK 162 Query: 545 LNRGYNESYGCMFTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDA--MQKGD 697 + + Y++ YG S +P N++GP+DNF L+ SHV+PALIR+ A Q GD Sbjct: 163 MCQAYHKQYGFDAISAMPTNLYGPNDNFDLEKSHVLPALIRKFHLAKLAQAGD 215 >UniRef50_Q0M6J4 Cluster: NAD-dependent epimerase/dehydratase:3-beta hydroxysteroid dehydrogenase/isomerase:dTDP-4-dehydrorhamnose reductase:Male sterility-like; n=1; Caulobacter sp. K31|Rep: NAD-dependent epimerase/dehydratase:3-beta hydroxysteroid dehydrogenase/isomerase:dTDP-4-dehydrorhamnose reductase:Male sterility-like - Caulobacter sp. K31 Length = 316 Score = 113 bits (273), Expect = 4e-24 Identities = 59/160 (36%), Positives = 85/160 (53%) Frame = +2 Query: 215 SKDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACH 394 S DGDL T AL + +P VIHLAA GG+ N + DF+ N+++ N+ +A Sbjct: 36 SADGDLTSFDVTRALLERVRPDAVIHLAAYSGGIGANRSWPADFYWRNITLVSNMYEAAA 95 Query: 395 KYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYG 574 + VK++V + C +P T PI E + G P + YS AK+M V + Y +G Sbjct: 96 QTGVKRIVYTMGGCSYPGTATSPISEDQMWEGYPQGDSAAYSAAKKMGIVAAKAYEAQHG 155 Query: 575 CMFTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKG 694 T ++P N+FG DN+ SHVIPA +RR +A G Sbjct: 156 ISSTVLVPGNLFGEFDNYRNGESHVIPAFLRRFHEAKLNG 195 >UniRef50_Q3B1R9 Cluster: GDP-L-fucose synthetase; n=3; Bacteria|Rep: GDP-L-fucose synthetase - Pelodictyon luteolum (strain DSM 273) (Chlorobium luteolum (strain DSM273)) Length = 319 Score = 112 bits (269), Expect = 1e-23 Identities = 58/181 (32%), Positives = 96/181 (53%) Frame = +2 Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 406 DL ++ + F+ KP V AA VGG+ N + +F +N+ + N++ A ++ V Sbjct: 41 DLTNQAAVQDFFSTEKPDQVYLAAAKVGGIHANNTYPAEFIYQNLMVECNVIDAAYRNGV 100 Query: 407 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 586 +K++ S+CI+P + P+ E + G +N Y+ AK L YN YG + Sbjct: 101 EKLLFLGSSCIYPKQAPQPMRENALLTGVLEPTNEPYAIAKIAGIKLCESYNRQYGTDYR 160 Query: 587 SVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDPTFXSDGEAXNHSDSLFIHXISA 766 SV+P N++GP DN+ ++SHVIPALIRR +A PT G + L++ ++A Sbjct: 161 SVMPTNLYGPGDNYHPENSHVIPALIRRFHEATVGNAPTVTIWGSGTPRREFLYVDDMAA 220 Query: 767 S 769 + Sbjct: 221 A 221 >UniRef50_Q2RXT6 Cluster: NAD-dependent epimerase/dehydratase; n=2; Proteobacteria|Rep: NAD-dependent epimerase/dehydratase - Rhodospirillum rubrum (strain ATCC 11170 / NCIB 8255) Length = 329 Score = 112 bits (269), Expect = 1e-23 Identities = 55/161 (34%), Positives = 90/161 (55%) Frame = +2 Query: 212 GSKDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQAC 391 G +D DL + EA ++P V+ AA+VGG+ N + +F +N+++ NI+ A Sbjct: 52 GREDLDLTRQQAVEAWMEANRPDAVVMAAALVGGIKANDRRSAEFIHQNLAVQTNIIHAA 111 Query: 392 HKYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESY 571 + V KV+ S+CI+P P+ E + +GP +N Y+ AK + + Y Y Sbjct: 112 WQAGVGKVLFLGSSCIYPRDVAQPMREDALLSGPLEPTNQWYAIAKIAGIRMAQAYRRQY 171 Query: 572 GCMFTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKG 694 GC + S +P N++GP DNF L HV+PAL+R++ +A +G Sbjct: 172 GCDYISAMPTNLYGPGDNFDLDGGHVLPALLRKIHEAKVEG 212 >UniRef50_Q7BR89 Cluster: GDP-6-deoxy-4-keto-D-mannose-3, 5-epimerase-4-reductase merA; n=4; Mycobacterium avium|Rep: GDP-6-deoxy-4-keto-D-mannose-3, 5-epimerase-4-reductase merA - Mycobacterium avium Length = 339 Score = 111 bits (267), Expect = 2e-23 Identities = 59/184 (32%), Positives = 94/184 (51%) Frame = +2 Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 406 DL D+ T ++ +P +I AA VGG+ N + DF EN+ I N+L A V Sbjct: 67 DLTDRAATFDFVSETRPQVIIDAAARVGGIMANNTYPADFLSENLRIQTNLLDAAVAVRV 126 Query: 407 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 586 +++ S+CI+P PI E+ + GP +N Y+ AK + + YG + Sbjct: 127 PRLLFLGSSCIYPKYAPQPIHESALLTGPLEPTNDAYAIAKIAGILQVQAVRRQYGLAWI 186 Query: 587 SVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDPTFXSDGEAXNHSDSLFIHXISA 766 S +P N++GP DNFS SH++PALIRR ++A G + G + L + +++ Sbjct: 187 SAMPTNLYGPGDNFSPSGSHLLPALIRRYEEAKAGGAEEVTNWGTGTPRRELLHVDDLAS 246 Query: 767 SCSF 778 +C F Sbjct: 247 ACLF 250 >UniRef50_A7IWS0 Cluster: Putative uncharacterized protein B395L; n=3; Chlorovirus|Rep: Putative uncharacterized protein B395L - Paramecium bursaria Chlorella virus NY2A (PBCV-NY2A) Length = 320 Score = 110 bits (265), Expect = 3e-23 Identities = 58/163 (35%), Positives = 86/163 (52%) Frame = +2 Query: 215 SKDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACH 394 SKD DL ++ + A F P +V AA VGG+ N + DF +N+ I N++ A Sbjct: 37 SKDLDLTNQREVNAFFEIELPEYVFLAAAKVGGIHANNSFGGDFIHDNLMIQTNVIHASK 96 Query: 395 KYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYG 574 + VKK+V S+CI+P + PI E + G +N Y+ AK + Y + YG Sbjct: 97 MFGVKKLVFLGSSCIYPKEAQNPIKEEYLMTGFLEPTNKPYAIAKIAGIEMCDAYRKQYG 156 Query: 575 CMFTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDPT 703 C F SV+P N+ GP+D + L + HV P LIR+ +A P+ Sbjct: 157 CNFVSVMPTNLSGPNDRYDLNNGHVFPVLIRKFCEAKVHNVPS 199 >UniRef50_Q124Z8 Cluster: NAD-dependent epimerase/dehydratase; n=2; Betaproteobacteria|Rep: NAD-dependent epimerase/dehydratase - Polaromonas sp. (strain JS666 / ATCC BAA-500) Length = 331 Score = 110 bits (265), Expect = 3e-23 Identities = 56/187 (29%), Positives = 93/187 (49%) Frame = +2 Query: 203 IFSGSKDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNIL 382 + + ++ DL D++ +++P + H+ A VGG+ N DF N+ I N++ Sbjct: 47 LLTSRQELDLSDQSAVFNWVDENRPELIFHVGAKVGGIHANSTLPADFLYSNLMIQSNVI 106 Query: 383 QACHKYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYN 562 A H + KK+V S C +P KT PI E + GP + Y+ +K + R Y Sbjct: 107 NAAHLFGAKKLVFVASNCTYPTKTAQPIPEEALMTGPLDENIRAYAISKIAGIEMCRAYR 166 Query: 563 ESYGCMFTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDPTFXSDGEAXNHSDS 742 + YG F SVIP N++GP DN+ + SHV+ ++RR +A G F G+ + Sbjct: 167 KQYGSNFISVIPPNLYGPGDNYHPQHSHVVAGILRRTHEAKLAGKSEFVVWGDGTPRREL 226 Query: 743 LFIHXIS 763 L + ++ Sbjct: 227 LHVDDLA 233 >UniRef50_A5ZJL9 Cluster: Putative uncharacterized protein; n=1; Bacteroides caccae ATCC 43185|Rep: Putative uncharacterized protein - Bacteroides caccae ATCC 43185 Length = 358 Score = 110 bits (265), Expect = 3e-23 Identities = 56/162 (34%), Positives = 92/162 (56%), Gaps = 2/162 (1%) Frame = +2 Query: 218 KDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHK 397 K+ DL D + F + P V+ AA VGG+ N+ + DF +N+ I N++ + Sbjct: 38 KELDLLDGVAVKQFFDEELPDAVVLAAAHVGGIMANLQYRADFIYQNLQIQQNVIGESFR 97 Query: 398 YNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGC 577 +NVKK++ STCI+P P+ E + P +N Y+ AK + +N YG Sbjct: 98 HNVKKLLFLGSTCIYPRDVAQPMKEDALLTSPLEYTNEPYAIAKIAGLKMCESFNLQYGT 157 Query: 578 MFTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDA--MQKGD 697 + +V+P N++GP+DNF L++SHV+PA+IR++ A + +GD Sbjct: 158 NYIAVMPTNLYGPNDNFHLENSHVLPAMIRKIHLAKCLNEGD 199 >UniRef50_Q8VU14 Cluster: GDP-4-keto-6-deoxy-D-mannose-3, 5-epimerase-4-reductase; n=32; Bacteria|Rep: GDP-4-keto-6-deoxy-D-mannose-3, 5-epimerase-4-reductase - Bacteroides fragilis Length = 360 Score = 110 bits (264), Expect = 5e-23 Identities = 56/162 (34%), Positives = 91/162 (56%), Gaps = 2/162 (1%) Frame = +2 Query: 218 KDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHK 397 K+ DL D + F + P +V AA VGG+ N + DF +N+ I N++ + Sbjct: 42 KELDLLDGATVKQFFDEEMPEYVFLAAAFVGGIMANSIYRADFIYKNLQIQQNVIGESFR 101 Query: 398 YNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGC 577 + VKK++ STCI+P P+ E ++ P +N Y+ AK + +N YG Sbjct: 102 HQVKKLLFLGSTCIYPRDAEQPMKEDVLLTSPLEYTNEPYAIAKIAGLKMCESFNLQYGT 161 Query: 578 MFTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDA--MQKGD 697 + +V+P N++GP+DNF L+ SHV+PA+IR++ A ++KGD Sbjct: 162 NYIAVMPTNLYGPNDNFDLERSHVLPAMIRKVHLAHCLKKGD 203 >UniRef50_Q93N55 Cluster: GDP-4-keto-6 deoxymannose epimerase/reductase; n=2; Coxiella burnetii|Rep: GDP-4-keto-6 deoxymannose epimerase/reductase - Coxiella burnetii Length = 332 Score = 109 bits (263), Expect = 6e-23 Identities = 55/182 (30%), Positives = 97/182 (53%) Frame = +2 Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 406 DL +K + FA + P +V AA VGG+ + H +DF R+N++I N+++A +Y V Sbjct: 41 DLTNKEKVFEFFANNCPEYVFLAAARVGGINDSNLHPVDFIRDNLAIQWNVIEASFRYKV 100 Query: 407 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 586 K+++ S+CI+ + P+ E ++G +N YS AK YN Y + Sbjct: 101 KRLLFLGSSCIYSNDAPRPLKEIYFNSGKLEPTNRAYSTAKIAGIEHCWAYNRQYKTQYL 160 Query: 587 SVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDPTFXSDGEAXNHSDSLFIHXISA 766 +P N+FGP+DN+ L++ HV+ +LI ++ A ++ P F G + L+ ++ Sbjct: 161 CAMPTNLFGPNDNYDLENGHVVASLISKIHQAKEQKKPNFVLWGSGKAKREFLYSDDLAE 220 Query: 767 SC 772 +C Sbjct: 221 AC 222 >UniRef50_A6VG32 Cluster: NAD-dependent epimerase/dehydratase; n=1; Methanococcus maripaludis C7|Rep: NAD-dependent epimerase/dehydratase - Methanococcus maripaludis C7 Length = 307 Score = 109 bits (263), Expect = 6e-23 Identities = 59/192 (30%), Positives = 97/192 (50%), Gaps = 1/192 (0%) Frame = +2 Query: 206 FSGSKDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQ 385 + SK +L DK Q E KP ++ +A +VGG++ NM N DF +N + N+L+ Sbjct: 34 YPSSKSVNLLDKNQVEEYIKSEKPEYLFMVAGLVGGIYGNMKRNADFLYQNSIMILNVLE 93 Query: 386 ACHKYNVK-KVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYN 562 + + K++ STCI+P + PI E + NG SN GY+ AK + V Y Sbjct: 94 SIKNCSKDTKILYTGSTCIYPKENPQPISENRLLNGLLEESNKGYALAKILGIVGCELYK 153 Query: 563 ESYGCMFTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDPTFXSDGEAXNHSDS 742 + YG V+P N++GP+D + L+ H IP+LI++ DA G ++ Sbjct: 154 KQYGINSICVMPTNMYGPNDTYDLEDGHFIPSLIKKFVDAKNNNLKELTFWGTGIPRREA 213 Query: 743 LFIHXISASCSF 778 L++ + +C + Sbjct: 214 LYVDDCADACIY 225 >UniRef50_A4YQ54 Cluster: Bifunctional GDP-fucose synthetase: GDP-4-dehydro-6-deoxy-D-mannose epimerase; GDP-4-dehydro-6-L-deoxygalactose reductase; n=17; root|Rep: Bifunctional GDP-fucose synthetase: GDP-4-dehydro-6-deoxy-D-mannose epimerase; GDP-4-dehydro-6-L-deoxygalactose reductase - Bradyrhizobium sp. (strain ORS278) Length = 318 Score = 108 bits (260), Expect = 1e-22 Identities = 59/182 (32%), Positives = 92/182 (50%) Frame = +2 Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 406 DL D+ A FA+ KP V AA VGG+ N +F +N++I N++ A H V Sbjct: 46 DLSDQAAVFAWFARAKPQVVFLAAAKVGGIVANNTLRAEFIYDNIAIATNVIHAAHVNGV 105 Query: 407 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 586 +K++ S+CI+P P+ E + GP +N Y+ AK + Y YG F Sbjct: 106 EKLMFLGSSCIYPKLAAQPLREDAMLTGPLEPTNEPYAIAKIAGIKMVEAYRSQYGADFI 165 Query: 587 SVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDPTFXSDGEAXNHSDSLFIHXISA 766 +V+P N++GP DN+ + SHV+ ALIRR +A P G + L++ ++ Sbjct: 166 NVMPTNLYGPGDNYHPEYSHVVAALIRRFHEAKLADAPEVIVWGTGKPRREFLYVDDMAD 225 Query: 767 SC 772 +C Sbjct: 226 AC 227 >UniRef50_Q5V3C6 Cluster: DTDP-glucose dehydratase; n=23; cellular organisms|Rep: DTDP-glucose dehydratase - Haloarcula marismortui (Halobacterium marismortui) Length = 333 Score = 108 bits (260), Expect = 1e-22 Identities = 54/179 (30%), Positives = 95/179 (53%) Frame = +2 Query: 215 SKDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACH 394 S + DLR++T F + V+HLAA VGG+ N + +F +N + +L+ Sbjct: 49 SNEYDLRERTDIRRAFTQSGADVVVHLAATVGGIGANRENPGRYFYDNAIMGIELLEMAR 108 Query: 395 KYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYG 574 +++V K + C +P+ T P E + +G P +N Y AK+ + +R Y + Y Sbjct: 109 QFDVDKFTILGTICSYPNHTEVPFSEDDLFDGYPEETNAPYGIAKKALLTQSRAYRKQYD 168 Query: 575 CMFTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDPTFXSDGEAXNHSDSLFI 751 ++P N++GP D+F L S+HVIPA+IR+ +A ++GD + + G + L++ Sbjct: 169 FNSIYLMPVNLYGPRDDFDLHSAHVIPAIIRKCIEARERGDDSITAWGTGEPTREFLYV 227 >UniRef50_Q9XDD7 Cluster: Bme10; n=1; Brucella melitensis|Rep: Bme10 - Brucella melitensis Length = 246 Score = 107 bits (256), Expect = 4e-22 Identities = 54/156 (34%), Positives = 85/156 (54%) Frame = +2 Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 406 DL + TE + H+P +I AA VGG+ N DF N++I N++ A H+ V Sbjct: 53 DLTRQGPTENFISGHRPDVIIIAAARVGGILANSRFPADFLYNNLAIGMNLIHAAHQIGV 112 Query: 407 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 586 ++++ S+CI+P P+ E + GP +N Y+ AK + +G F Sbjct: 113 ERLLWLGSSCIYPRDAAQPLTEDALLTGPLEPTNEAYAIAKIAGLKYAQSCARQFGDRFI 172 Query: 587 SVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKG 694 + +P N++GP+DNF SSHV+PALIRR+ +A +G Sbjct: 173 TAMPTNLYGPNDNFDPTSSHVLPALIRRVHEARMRG 208 >UniRef50_Q1VHC4 Cluster: GDP-fucose synthetase chain A; n=1; Psychroflexus torquis ATCC 700755|Rep: GDP-fucose synthetase chain A - Psychroflexus torquis ATCC 700755 Length = 311 Score = 105 bits (251), Expect = 2e-21 Identities = 57/192 (29%), Positives = 96/192 (50%) Frame = +2 Query: 203 IFSGSKDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNIL 382 I K +L D+ +T K KP VI AA VGG+ NM F EN+ I +NI+ Sbjct: 35 IIEDKKKLNLLDQNKTFKFLEKKKPDFVIIAAARVGGIVANMKFKSKFIYENLQIQNNII 94 Query: 383 QACHKYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYN 562 + VK + S+CI+P + P+ E + +GP +N Y+ AK + Y+ Sbjct: 95 HGSYLAGVKNLFLLGSSCIYPKFSKQPMKEKYLLSGPLEETNDAYAIAKIAGIKMCENYS 154 Query: 563 ESYGCMFTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDPTFXSDGEAXNHSDS 742 +++ F S++P N++GP+DN+ L +SH PAL++++ A + F G + Sbjct: 155 KNFNLNFKSLMPPNLYGPNDNYDLSNSHFYPALLKKIHTAKIQNKKNFLIWGSGKAKREL 214 Query: 743 LFIHXISASCSF 778 +F+ + + F Sbjct: 215 MFVDDFADAVIF 226 >UniRef50_O49213 Cluster: GDP-L-fucose synthase 1; n=181; root|Rep: GDP-L-fucose synthase 1 - Arabidopsis thaliana (Mouse-ear cress) Length = 312 Score = 105 bits (251), Expect = 2e-21 Identities = 57/184 (30%), Positives = 95/184 (51%) Frame = +2 Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 406 DL + E+ F++ KP +VI AA VGG+ N + DF N+ I N++ + +++ V Sbjct: 42 DLTRQADVESFFSQEKPVYVILAAAKVGGIHANNTYPADFIGVNLQIQTNVIHSAYEHGV 101 Query: 407 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 586 KK++ S+CI+P PI E+ + +N Y+ AK + Y +G Sbjct: 102 KKLLFLGSSCIYPKFAPQPIPESALLTASLEPTNEWYAIAKIAGIKTCQAYRIQHGWDAI 161 Query: 587 SVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDPTFXSDGEAXNHSDSLFIHXISA 766 S +P N++GP+DNF ++SHV+PAL+RR +A G G + L + ++ Sbjct: 162 SGMPTNLYGPNDNFHPENSHVLPALMRRFHEAKVNGAEEVVVWGTGSPLREFLHVDDLAD 221 Query: 767 SCSF 778 +C F Sbjct: 222 ACVF 225 >UniRef50_Q7MV22 Cluster: GDP-fucose synthetase; n=5; Bacteria|Rep: GDP-fucose synthetase - Porphyromonas gingivalis (Bacteroides gingivalis) Length = 357 Score = 104 bits (249), Expect = 3e-21 Identities = 52/149 (34%), Positives = 80/149 (53%) Frame = +2 Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 406 DL D F K +P +V AA VGG+ N DF N+ I NI+ +++ V Sbjct: 41 DLLDAVAVREFFDKEEPQYVFLAAAYVGGIVANNRFRADFIYRNLGIQQNIIGESYRHRV 100 Query: 407 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 586 K++ STCI+P P+ E + P +N Y+ AK + +N YG + Sbjct: 101 SKLMFLGSTCIYPRDARQPMREEELLTAPLEYTNEPYAIAKIAGLKMCESFNLQYGTNYI 160 Query: 587 SVIPCNVFGPHDNFSLKSSHVIPALIRRM 673 +V+P N++GP+DNF L+ SHV+PA+IR++ Sbjct: 161 AVMPTNLYGPNDNFDLERSHVLPAMIRKI 189 >UniRef50_A2BXU6 Cluster: Putative fucose synthetase; n=1; Prochlorococcus marinus str. MIT 9515|Rep: Putative fucose synthetase - Prochlorococcus marinus (strain MIT 9515) Length = 320 Score = 99.5 bits (237), Expect = 9e-20 Identities = 55/156 (35%), Positives = 83/156 (53%) Frame = +2 Query: 218 KDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHK 397 KD DLR++ HKP +I AA VGG+ N +F +N+ I NI+ A K Sbjct: 40 KDLDLRNQIDVNNFIGIHKPDKIILSAAKVGGIQANQNFKCEFLYDNLMIQTNIIDAAAK 99 Query: 398 YNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGC 577 N K +V S+CI+P ++ PI E + G +N Y+ AK + L + Y E Y Sbjct: 100 NNTKTLVFIGSSCIYPRESEQPIKENYLLTGLLEPTNEPYALAKIVGLKLAKLYAEKYNI 159 Query: 578 MFTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAM 685 + CN++G +DNF L +SHV+ +L+R+ DA+ Sbjct: 160 QCICPMFCNLYGNNDNFDLINSHVLSSLVRKFVDAV 195 >UniRef50_Q8L2G9 Cluster: Fcl; n=2; Enterobacteriaceae|Rep: Fcl - Erwinia chrysanthemi Length = 312 Score = 98.7 bits (235), Expect = 1e-19 Identities = 52/164 (31%), Positives = 85/164 (51%), Gaps = 1/164 (0%) Frame = +2 Query: 260 FAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCI 439 F +H+P +V HLA++V GL N+ + L N IN N++ ACHK+NVKK+ + Sbjct: 52 FNQHQPDYVFHLASLVFGLKGNLDNQLKSISNNTIINQNVILACHKFNVKKIFFAGTVAS 111 Query: 440 FP-DKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGP 616 +P P+DE + G PH +GY+ +KR + N+ + + + N+FG Sbjct: 112 YPFPYVQLPLDEGDLMLGEPHGGEYGYAMSKRHALAYLKILNQYHNVDYCYALFTNLFGA 171 Query: 617 HDNFSLKSSHVIPALIRRMDDAMQKGDPTFXSDGEAXNHSDSLF 748 +D F + HVIP+LI + +++ +GD G D L+ Sbjct: 172 NDKFDPINGHVIPSLIDKTYNSLLRGDNQLTVWGRPETTRDFLY 215 >UniRef50_O84974 Cluster: O-antigen biosynthesis protein; n=5; Helicobacter|Rep: O-antigen biosynthesis protein - Helicobacter pylori (Campylobacter pylori) Length = 310 Score = 98.7 bits (235), Expect = 1e-19 Identities = 51/164 (31%), Positives = 82/164 (50%) Frame = +2 Query: 230 LRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVK 409 L DK +A ++KPT +IH A VGG+ NM + EN+ + + + VK Sbjct: 41 LLDKDNVQAYLKEYKPTGIIHCAGRVGGIVANMNDLSTYMVENLLMGLYLFSSALDLGVK 100 Query: 410 KVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTS 589 K ++ S+C +P P+ E+ + NG +N GY+ AK + + G + + Sbjct: 101 KAINLASSCAYPKYAPNPLKESDLLNGSLEPTNEGYALAKLSVMKYCEYVSTEKGGFYKT 160 Query: 590 VIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDPTFXSDGE 721 ++PCN++G D F K +H+IP LI RM A K + F G+ Sbjct: 161 LVPCNLYGEFDKFEEKIAHMIPGLIARMHTAKLKNEKNFAMWGD 204 >UniRef50_A1B1K8 Cluster: NAD-dependent epimerase/dehydratase; n=2; Alphaproteobacteria|Rep: NAD-dependent epimerase/dehydratase - Paracoccus denitrificans (strain Pd 1222) Length = 307 Score = 97.9 bits (233), Expect = 3e-19 Identities = 52/169 (30%), Positives = 86/169 (50%), Gaps = 3/169 (1%) Frame = +2 Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 406 DL D A+ +P V+H A VGG+ NMA + + N I N++ AC + Sbjct: 37 DLCDARALRDWLARQRPDAVVHAAGAVGGIQANMAEPVRYLAGNALIGLNLITACRDAGI 96 Query: 407 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRM-IDVLNRGYNESYGCMF 583 +++ S+C++P + E + G SN GY+ AK M + +++ E + Sbjct: 97 PVLINLSSSCVYPRDLGRDLSEEQILTGALEPSNEGYALAKIMAMRLVDYTCREDRSLQW 156 Query: 584 TSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDPT--FXSDGEA 724 ++IPCN++GPHD F + SH++PA+I ++ A +G T DG A Sbjct: 157 RTLIPCNLYGPHDKFDPRRSHLLPAIIHKIHRARVEGHETVEIWGDGTA 205 >UniRef50_A5GHX4 Cluster: GDP-L fucose synthetase; n=25; Bacteria|Rep: GDP-L fucose synthetase - Synechococcus sp. (strain WH7803) Length = 343 Score = 96.7 bits (230), Expect = 6e-19 Identities = 57/191 (29%), Positives = 91/191 (47%) Frame = +2 Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 406 DL D + +P V+ AA VGG+ N + DF +N+ I +++A + V Sbjct: 53 DLLDDSAVRDWMEAQRPDVVVLAAATVGGIEANRSRPADFLLQNLRIETQVIEAAWRCGV 112 Query: 407 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 586 ++++ S+CI+P PI E + G +N Y+ AK L +G Sbjct: 113 RRLLFLGSSCIYPKFADQPIREEALLTGALEPTNAWYAIAKIAGIKLAEALRLQHGFDAI 172 Query: 587 SVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDPTFXSDGEAXNHSDSLFIHXISA 766 S++P N++GP DN+ SHV+PALIRR +A Q+GD + G + L + Sbjct: 173 SLMPTNLYGPGDNYHPTGSHVLPALIRRFHEAKQRGDASVTCWGTGTPLREFLHADDLGE 232 Query: 767 SCSFGVLXNST 799 +C F + ST Sbjct: 233 ACVFALEHWST 243 >UniRef50_Q9AQ09 Cluster: Putative nodulation NAD-dependent nucleotide sugar epimerase; n=1; Bradyrhizobium sp. WM9|Rep: Putative nodulation NAD-dependent nucleotide sugar epimerase - Bradyrhizobium sp. (strain WM9) Length = 289 Score = 92.3 bits (219), Expect = 1e-17 Identities = 55/185 (29%), Positives = 92/185 (49%) Frame = +2 Query: 218 KDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHK 397 ++ DL ++ FAK +P + AA VGG+ N +F +N++I N++QA H+ Sbjct: 23 REVDLCNQAAVFDWFAKVRPQVIFLAAAKVGGIVANATLRAEFIYDNIAIAANVIQAAHQ 82 Query: 398 YNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGC 577 +K++ S+CI+P P+ E V GP +M++ Y YG Sbjct: 83 NGAEKLMFLGSSCIYPKLAAQPLREDSVLTGP---------LEIKMVE----AYRSQYGS 129 Query: 578 MFTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDPTFXSDGEAXNHSDSLFIHX 757 F SV+P N++GP DN+ + SHV+ ALIRR +A G + G + L++ Sbjct: 130 DFISVMPTNLYGPGDNYHPEYSHVVAALIRRFHEAKVSGARSVVVWGTGTPRREFLYVDD 189 Query: 758 ISASC 772 ++ +C Sbjct: 190 MADAC 194 >UniRef50_Q8VQ41 Cluster: WbdJ; n=13; Bacteria|Rep: WbdJ - Escherichia coli Length = 307 Score = 91.9 bits (218), Expect = 2e-17 Identities = 50/157 (31%), Positives = 79/157 (50%), Gaps = 1/157 (0%) Frame = +2 Query: 215 SKDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACH 394 S + +L D H P +IH A +VGG+ N+ +DF N+ + NI+ Sbjct: 32 SSELNLLDNKAVHDYITCHSPDLIIHAAGLVGGIQANIKRPVDFLVSNLKMGVNIVNEAK 91 Query: 395 KYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGY-NESY 571 VK ++ S+C++P I E + G +N GY+ AK + L ES Sbjct: 92 NCGVKNFINLGSSCMYPKGIDTAISEDALLTGKLEHTNEGYALAKITVAKLCEYITKESE 151 Query: 572 GCMFTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDA 682 G + ++IPCN++G +D F SSH+IPA+I R+ +A Sbjct: 152 GYHYKTIIPCNLYGKYDKFDEHSSHMIPAVINRIHNA 188 >UniRef50_P33217 Cluster: Nodulation protein nolK; n=2; Alphaproteobacteria|Rep: Nodulation protein nolK - Azorhizobium caulinodans Length = 312 Score = 89.8 bits (213), Expect = 7e-17 Identities = 48/180 (26%), Positives = 92/180 (51%) Frame = +2 Query: 215 SKDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACH 394 S D DLR+ E + P V+H A +VGG+ N+A + F +N ++ N++ + Sbjct: 36 SVDLDLRNAEAVEQYIRRQLPDVVVHAAGVVGGIHANIADPIHFLADNAAMALNVVMSSF 95 Query: 395 KYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYG 574 + V +++ S+C++P P+ E + GP +N GY+ AK + + ++ Sbjct: 96 RSEVVTLINLSSSCMYPACIEGPLKECDILRGPFEVTNEGYALAKTVGLKICEYIDKLPN 155 Query: 575 CMFTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDPTFXSDGEAXNHSDSLFIH 754 + ++I CN++G DNF + SH++PA+I ++ A Q G + G+ + +F + Sbjct: 156 FNYKTLIACNLYGVGDNFDPRRSHLLPAIIEKIHKASQCGSESVSIWGDGTARREFMFAY 215 >UniRef50_Q2BI22 Cluster: DTDP-glucose dehydratase; n=1; Neptuniibacter caesariensis|Rep: DTDP-glucose dehydratase - Neptuniibacter caesariensis Length = 312 Score = 87.4 bits (207), Expect = 4e-16 Identities = 50/160 (31%), Positives = 81/160 (50%) Frame = +2 Query: 215 SKDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACH 394 S + DL Q E + HLAA VGG+ + AH + F N+ +N +L A Sbjct: 37 SSECDLLCYEQIEVSLQSESFDLIFHLAADVGGIGYMQAHGAEVFENNLLMNTQLLHAAR 96 Query: 395 KYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYG 574 + V K+V+ S +P + P E+ + +G P GY+YAKR + V + + +G Sbjct: 97 RNGVGKLVNIASINCYPAEAEAPYLESSLFDGQPALPVLGYAYAKRAMLVHSELARQQFG 156 Query: 575 CMFTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKG 694 ++I +V+GP ++FSL ++ V+PA + R DA G Sbjct: 157 FNSINLILDSVYGPGESFSLDTARVLPANVARFVDAAHSG 196 >UniRef50_Q67WR5 Cluster: Putative GDP-L-fucose synthase 2; n=4; Oryza sativa|Rep: Putative GDP-L-fucose synthase 2 - Oryza sativa subsp. japonica (Rice) Length = 347 Score = 85.0 bits (201), Expect = 2e-15 Identities = 51/157 (32%), Positives = 78/157 (49%), Gaps = 1/157 (0%) Frame = +2 Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKY-N 403 DL + EA FA P +VI AA VGG+ + A ++ EN+ I N++ A + + Sbjct: 71 DLACQAAVEAFFAAELPRYVILAAAKVGGVHASSAAPAEYLTENLRITVNVVDAARRCGS 130 Query: 404 VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 583 V+K++ S+ I+P P E+ + GPP + Y+ K + + YG Sbjct: 131 VRKLLVLASSTIYPADAPQPTPESALLTGPPAEGSEWYAIPKIAGIKMCQAVRAEYGLDA 190 Query: 584 TSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKG 694 + P N++GP F + SHVIPALIRR A +G Sbjct: 191 IAAAPNNLYGPRHPFPPEHSHVIPALIRRFHRAKLEG 227 >UniRef50_A0R4U4 Cluster: NAD dependent epimerase/dehydratase family protein; n=1; Mycobacterium smegmatis str. MC2 155|Rep: NAD dependent epimerase/dehydratase family protein - Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) Length = 323 Score = 73.7 bits (173), Expect = 5e-12 Identities = 49/156 (31%), Positives = 81/156 (51%), Gaps = 5/156 (3%) Frame = +2 Query: 218 KDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGL--FHNMAHNLDFFRENMSINDNILQAC 391 + GDLR + A A THVIHLAA+VGG+ FH + H L N + +++ A Sbjct: 48 RTGDLRSADEARA--AVDGCTHVIHLAAIVGGIANFHRLPHTL--LEMNTGLYNSVFSAA 103 Query: 392 HKYNVKKVVSCLSTCIFPDKTTYP-IDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNES 568 + V+++V S+ +F T +P +E ++ PP S+ Y ++K ++ R +E Sbjct: 104 LREGVERLVYVSSSMVFEQATQFPTTEEHLLDCRPPRSA---YGFSKLTGEIYCRAVHEE 160 Query: 569 YGCMFTSVIPCNVFGPHD--NFSLKSSHVIPALIRR 670 +G FT P N +GP + + +H +P LIR+ Sbjct: 161 HGLPFTICRPFNAYGPGELPDTEPGIAHAVPDLIRK 196 >UniRef50_Q30CR4 Cluster: LipDig4; n=3; Streptomyces|Rep: LipDig4 - Streptomyces aureofaciens Length = 355 Score = 61.3 bits (142), Expect = 3e-08 Identities = 42/151 (27%), Positives = 64/151 (42%), Gaps = 2/151 (1%) Frame = +2 Query: 227 DLRDKTQTEALFAKHKPTH--VIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKY 400 DL D T A P ++H AA+ G + NM + N+L+A Sbjct: 85 DLLDDTALSAALRSVTPRVDLIVHCAALYGNADFKKRNPALILDANMRMASNVLRAARAC 144 Query: 401 NVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 580 +V VV S I+ + P E + P + GY+ AK ++L + YG Sbjct: 145 DVGDVVMMGSAEIYSELAPSPAREDDDYRRYPVPTQNGYALAKIYTEMLAEFFRTQYGMR 204 Query: 581 FTSVIPCNVFGPHDNFSLKSSHVIPALIRRM 673 P NV+GP D+F S V+P+L+ R+ Sbjct: 205 IFVPRPTNVYGPRDDFDASVSRVVPSLMNRI 235 >UniRef50_Q1J353 Cluster: GDP-L-fucose synthase; n=1; Deinococcus geothermalis DSM 11300|Rep: GDP-L-fucose synthase - Deinococcus geothermalis (strain DSM 11300) Length = 316 Score = 61.3 bits (142), Expect = 3e-08 Identities = 42/188 (22%), Positives = 79/188 (42%) Frame = +2 Query: 215 SKDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACH 394 +++ DLR+K Q A F K P +V + V G + + + +N+ + N + A + Sbjct: 39 ARELDLREKDQVHAFFEKELPDYVFVSSVKVEGPVRDAIYPAQWLHDNLLVMANTIHAAY 98 Query: 395 KYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYG 574 Y+V+K+V + + D P + + + + + L Y YG Sbjct: 99 LYDVEKLVCIDCSSTYADLGALPRTMSYLQAELIEETQRVCTVVSQTTTELCDSYRRQYG 158 Query: 575 CMFTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDPTFXSDGEAXNHSDSLFIH 754 C F S + +++GP S + S V+ AL+ M A + G + D L+ Sbjct: 159 CDFVSAVFSSLYGPPLGGSGQRSSVVLALLHDMQRAKETGQAAVRWPSDDRWCRDLLYAD 218 Query: 755 XISASCSF 778 ++ +C F Sbjct: 219 DMADACLF 226 >UniRef50_Q18EM2 Cluster: Nucleoside-diphosphate-sugar epimerase; n=1; Haloquadratum walsbyi DSM 16790|Rep: Nucleoside-diphosphate-sugar epimerase - Haloquadratum walsbyi (strain DSM 16790) Length = 345 Score = 59.7 bits (138), Expect = 8e-08 Identities = 42/149 (28%), Positives = 71/149 (47%), Gaps = 4/149 (2%) Frame = +2 Query: 284 VIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDK---- 451 V HLAA VGG+ + N+ ++ +N ++L+A +V + + S C++ + Sbjct: 85 VYHLAASVGGIHYIQRENVHGLTPSVLMNQHMLEAARIQDVDRFLFASSACVYRQQHDEL 144 Query: 452 TTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPHDNFS 631 + D+ + N PHS+ Y +AK + +V Y+ +V N +GP +N Sbjct: 145 NRFSEDQAIPAN--PHST---YGWAKVLGEVACDAYHTDTTVDTGAVRIFNAYGPRENLD 199 Query: 632 LKSSHVIPALIRRMDDAMQKGDPTFXSDG 718 SSHVIPAL R++ +A DG Sbjct: 200 PDSSHVIPALCRKVIEADDGDSIELFGDG 228 >UniRef50_A6GLY7 Cluster: Putative uncharacterized protein; n=1; Limnobacter sp. MED105|Rep: Putative uncharacterized protein - Limnobacter sp. MED105 Length = 294 Score = 57.2 bits (132), Expect = 4e-07 Identities = 53/192 (27%), Positives = 83/192 (43%), Gaps = 2/192 (1%) Frame = +2 Query: 149 VIERDRQKRNSDYDSETWIFSGS--KDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFH 322 VI D + E W+ + +GD+RD++ E L A+ HLAA+V + Sbjct: 12 VIVLDNLSSGRRENIENWLGPNTCLVEGDIRDQSLVENLLAE--TAGAFHLAALVS-VPQ 68 Query: 323 NMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHS 502 ++ + F N+ N+L+A K KK+V S ++ ++ +YP+ ETM G P S Sbjct: 69 SIERPTESFSINLEGTLNLLEASRKQGNKKIVFASSAAVYGNRHSYPVSETMA--GQPIS 126 Query: 503 SNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDA 682 Y K M + + Y + NV+GP + S S VI I R+ Sbjct: 127 P---YGLHKLMCEQHAELFANLYNVNSVGMRFFNVYGPRQDPSSPYSGVISIFIDRLRRG 183 Query: 683 MQKGDPTFXSDG 718 + PT DG Sbjct: 184 LA---PTIYGDG 192 >UniRef50_Q5SKQ2 Cluster: UDP-glucose 4-epimerase; n=4; Thermus|Rep: UDP-glucose 4-epimerase - Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) Length = 311 Score = 56.4 bits (130), Expect = 8e-07 Identities = 42/134 (31%), Positives = 62/134 (46%), Gaps = 1/134 (0%) Frame = +2 Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 406 DLRDK E F + +PTHV H AA LD F N+ N+L+AC +Y V Sbjct: 51 DLRDKEGVERAFREFRPTHVSHQAAQASVKVSVEDPVLD-FEVNLLGGLNLLEACRQYGV 109 Query: 407 KKVV-SCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 583 +K+V + I+ + P E PP + Y+ +K + Y +SYG + Sbjct: 110 EKLVFASTGGAIYGE---VPEGERAEETWPPRPKS-PYAASKAAFEHYLSVYGQSYGLKW 165 Query: 584 TSVIPCNVFGPHDN 625 S+ NV+GP + Sbjct: 166 VSLRYGNVYGPRQD 179 >UniRef50_Q83DA9 Cluster: NAD dependent epimerase/dehydratase family protein; n=9; Bacteria|Rep: NAD dependent epimerase/dehydratase family protein - Coxiella burnetii Length = 330 Score = 54.0 bits (124), Expect = 4e-06 Identities = 46/163 (28%), Positives = 73/163 (44%), Gaps = 2/163 (1%) Frame = +2 Query: 236 DKTQTEALFAKHKPTH-VIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKK 412 D QT+ L K V H AA+ L + F+ N+ N+L+ C VK+ Sbjct: 64 DINQTDILNTALKGVDGVFHFAAL--WLLQCYEYPRSAFQTNIQGTFNVLETCVAQGVKR 121 Query: 413 VVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSV 592 +V S ++ D P+ E H P +S Y K + + Y+ YG F + Sbjct: 122 LVFSSSASVYGDALEEPMTEA--H---PFNSRTFYGATKIAGEAMATAYHHRYGLPFVGL 176 Query: 593 IPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDP-TFXSDG 718 NV+GP ++ + +++ A+I +M DA+ KG P T DG Sbjct: 177 RYMNVYGPRQDY--RGAYI--AVIMKMLDALDKGQPMTLYGDG 215 >UniRef50_Q1GN57 Cluster: NAD-dependent epimerase/dehydratase; n=24; Alphaproteobacteria|Rep: NAD-dependent epimerase/dehydratase - Silicibacter sp. (strain TM1040) Length = 333 Score = 53.6 bits (123), Expect = 6e-06 Identities = 36/131 (27%), Positives = 57/131 (43%) Frame = +2 Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 403 G L D + L A HKP VIHLAA G+ H++ D+ N+ +L+A + Sbjct: 61 GKLEDPGRLMGLLADHKPNAVIHLAAQ-AGVRHSIDAPRDYLEANLIGTFEVLEAARAHP 119 Query: 404 VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 583 + ++ ++ + T P DE H H +F Y+ K+ + + Y YG Sbjct: 120 PEHIMIASTSSAYGANTNIPFDE---HQKADHQMSF-YAATKKAGETMAHSYAHLYGLPT 175 Query: 584 TSVIPCNVFGP 616 T V+GP Sbjct: 176 TMFRFFTVYGP 186 >UniRef50_Q55412 Cluster: Slr0583 protein; n=3; Chroococcales|Rep: Slr0583 protein - Synechocystis sp. (strain PCC 6803) Length = 310 Score = 53.2 bits (122), Expect = 7e-06 Identities = 42/165 (25%), Positives = 72/165 (43%), Gaps = 4/165 (2%) Frame = +2 Query: 236 DKTQTEAL--FAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVK 409 D TQ ++L F K + HLAA ++H + + N +N N+L H + Sbjct: 36 DLTQPDSLHQFTKGSFDQIYHLAAWTQAGDFCLSHPGEQWLINQKLNTNVLDWWHSQQPQ 95 Query: 410 -KVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 586 K++ ++C + P++E G P S F Y+ KRM+ + YG + Sbjct: 96 AKLIFMGTSCAYDPNL--PLEEEYYLTGLPIDSLFTYAMTKRMLYAGALALQKQYGLKYL 153 Query: 587 SVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDP-TFXSDG 718 ++P ++GP + + H I LIR++ G+ T DG Sbjct: 154 CLVPSTLYGPGYHTDGRQMHFIFDLIRKIIRGKLYGETVTLWGDG 198 >UniRef50_A5GEL7 Cluster: NAD-dependent epimerase/dehydratase precursor; n=1; Geobacter uraniumreducens Rf4|Rep: NAD-dependent epimerase/dehydratase precursor - Geobacter uraniumreducens Rf4 Length = 336 Score = 52.8 bits (121), Expect = 1e-05 Identities = 41/166 (24%), Positives = 79/166 (47%), Gaps = 6/166 (3%) Frame = +2 Query: 281 HVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFP----- 445 +V HLA +VGG+ ++ L FR+N++I+ N++ AC + + + C +P Sbjct: 82 YVFHLADIVGGIQFAFSNELFIFRQNITIDTNVVSACITNGIGNYIYVGTACSYPKYLQM 141 Query: 446 DKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPC-NVFGPHD 622 +K + E V+ P SS +G+S +++ G + ++ NV+GP Sbjct: 142 NKGITALKEDQVYPAEPESS-YGWS---KLMGEYGADLALKSGRINVGILRFHNVYGPGV 197 Query: 623 NFSLKSSHVIPALIRRMDDAMQKGDPTFXSDGEAXNHSDSLFIHXI 760 F ++ V+P+L+R+ A++ F G + D ++I I Sbjct: 198 EFEGNTAQVLPSLMRK---AIRFPQEDFIVWGSGNQYRDFVYIDDI 240 >UniRef50_Q2NIA3 Cluster: Putative UDP-glucose 4-epimerase; n=1; Methanosphaera stadtmanae DSM 3091|Rep: Putative UDP-glucose 4-epimerase - Methanosphaera stadtmanae (strain DSM 3091) Length = 315 Score = 52.8 bits (121), Expect = 1e-05 Identities = 41/171 (23%), Positives = 78/171 (45%) Frame = +2 Query: 281 HVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTY 460 ++ H AA++ +F ++ + N+ + N+LQA ++ N+KKV+S S ++ + Sbjct: 74 YLFHEAALIS-VFESIEQPKATNKTNIDGSFNVLQAAYESNIKKVISASSAAVYGETEVL 132 Query: 461 PIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPHDNFSLKS 640 P ET+ P Y+ +K ++++ + + ++Y + NVFGP Sbjct: 133 PNVETL-----PLQPLSPYAVSKALLELYSYTFTQTYHLPTACLRYFNVFGPRQKADSPY 187 Query: 641 SHVIPALIRRMDDAMQKGDPTFXSDGEAXNHSDSLFIHXISASCSFGVLXN 793 S VIP I + + P DGE D +++ I A ++ V N Sbjct: 188 SGVIPKFISAL---LNNETPVIYGDGEQTR--DFIYVKNI-AKANYEVAIN 232 >UniRef50_Q9ZHQ3 Cluster: 4-ketoreductase; n=2; Actinomycetales|Rep: 4-ketoreductase - Streptomyces fradiae Length = 336 Score = 50.4 bits (115), Expect = 5e-05 Identities = 37/151 (24%), Positives = 62/151 (41%), Gaps = 3/151 (1%) Frame = +2 Query: 227 DLRDKTQTEALFAKHKPTH--VIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKY 400 DL D+ T F + P VIH A + G + H+ N+ ++L Sbjct: 65 DLCDEAATRRAFQEWAPGADVVIHCAGLDGNAQYKRDHSASVLDANVRGTAHVLNTARDT 124 Query: 401 NVKKVVSCLSTCIFPDKTTYPI-DETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGC 577 VV ST ++ P ++ + PH+ N GY +K +++ + +G Sbjct: 125 GAGAVVLLSSTEVYCAPRDSPAREDEEIRRYVPHAGN-GYVLSKIFCEIMAELHGAEFGS 183 Query: 578 MFTSVIPCNVFGPHDNFSLKSSHVIPALIRR 670 V P NV+GP D + VIP+++ R Sbjct: 184 RIFRVRPGNVYGPRDGNGGTRTRVIPSMVAR 214 >UniRef50_Q9K7I2 Cluster: UDP-glucose 4-epimerase; n=17; cellular organisms|Rep: UDP-glucose 4-epimerase - Bacillus halodurans Length = 308 Score = 50.0 bits (114), Expect = 7e-05 Identities = 44/176 (25%), Positives = 80/176 (45%), Gaps = 2/176 (1%) Frame = +2 Query: 242 TQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSI--NDNILQACHKYNVKKV 415 ++ + +F+K KP +VIH AA V + NL + +I N+L C +Y V KV Sbjct: 58 SELKDIFSKEKPNYVIHHAAQVD---VTKSINLPTYDAETNIIGTINLLSCCCQYEVDKV 114 Query: 416 VSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVI 595 + S ++ D D ++ + P +F Y +K + ++ R +++ YG +T Sbjct: 115 IYASSCAVYGDTG----DSSITEDFPIQPISF-YGISKSVPEMYIRQFHDLYGLKYTIFR 169 Query: 596 PCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDPTFXSDGEAXNHSDSLFIHXIS 763 NV+GP S VI + A+++ P +GE D +++ I+ Sbjct: 170 YANVYGPRQT-SKGEGGVISIFTTK---ALKREQPIIYGNGEQTR--DFIYVEDIA 219 >UniRef50_A5GIA6 Cluster: NAD dependent epimerase/dehydratase; n=19; Bacteria|Rep: NAD dependent epimerase/dehydratase - Synechococcus sp. (strain WH7803) Length = 343 Score = 49.6 bits (113), Expect = 9e-05 Identities = 31/122 (25%), Positives = 59/122 (48%) Frame = +2 Query: 251 EALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLS 430 + LFA+ KP V++LAA G+ +++ + + + N+ NIL+ C + V+ +V S Sbjct: 77 QELFAREKPRVVVNLAAQ-AGVRYSLENPAAYIQSNLVGFGNILEGCRHHGVENLVYASS 135 Query: 431 TCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVF 610 + ++ P E N P Y+ +K+ +++ Y+ YG T + V+ Sbjct: 136 SSVYGGNRNLPFHEQQPVNHPVSL----YAASKKANELMAHTYSHLYGLPATGLRFFTVY 191 Query: 611 GP 616 GP Sbjct: 192 GP 193 >UniRef50_Q12VP0 Cluster: NAD-dependent epimerase/dehydratase; n=1; Methanococcoides burtonii DSM 6242|Rep: NAD-dependent epimerase/dehydratase - Methanococcoides burtonii (strain DSM 6242) Length = 303 Score = 49.2 bits (112), Expect = 1e-04 Identities = 43/150 (28%), Positives = 69/150 (46%) Frame = +2 Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 406 D D T E + K ++HLA M + + H D + N N+L+ C +V Sbjct: 45 DSIDITNWEQVKTIPKRDVLVHLAGMTN-IPESFNHPRDVYTINTFGTLNMLEWCRLNDV 103 Query: 407 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 586 K+ + ST ++ + P+DE H P N YS +K + + L Y YG Sbjct: 104 KRFIYA-STFVYGNPQYTPVDEK--H---PTLPNNPYSQSKLIGEELCNAYCRDYGIDVI 157 Query: 587 SVIPCNVFGPHDNFSLKSSHVIPALIRRMD 676 S+ NV+GPH K ++IP +IR+++ Sbjct: 158 SLRLFNVYGPHQ----KGDYLIPHIIRQLE 183 >UniRef50_Q8DJM2 Cluster: Nucleotide sugar epimerase; n=61; cellular organisms|Rep: Nucleotide sugar epimerase - Synechococcus elongatus (Thermosynechococcus elongatus) Length = 338 Score = 48.4 bits (110), Expect = 2e-04 Identities = 34/130 (26%), Positives = 60/130 (46%) Frame = +2 Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 406 DL D+ LFA P VIHLAA G+ +++ + + N+ +IL+AC + V Sbjct: 64 DLVDRLGVNQLFADFSPQKVIHLAAQ-AGVRYSLENPFAYIDSNIVGFLHILEACRHHRV 122 Query: 407 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 586 + +V S+ ++ P VH+ H + Y+ K+ +++ Y+ Y T Sbjct: 123 EHLVYASSSSVYGANKKLPFS---VHDNVDHPLSL-YAATKKANELMAHTYSHLYNIPTT 178 Query: 587 SVIPCNVFGP 616 + V+GP Sbjct: 179 GLRFFTVYGP 188 >UniRef50_Q5KWG9 Cluster: Nucleotide sugar epimerase; n=1; Geobacillus kaustophilus|Rep: Nucleotide sugar epimerase - Geobacillus kaustophilus Length = 314 Score = 48.4 bits (110), Expect = 2e-04 Identities = 37/130 (28%), Positives = 61/130 (46%) Frame = +2 Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 406 DL D T+ F++ +P V HLAA+ G + +++AH L + ++ N+L A + V Sbjct: 60 DLLDGEATKRWFSQFRPDVVYHLAALPG-VPYSLAHPLAYIDYDIKATVNVLAAAGEAGV 118 Query: 407 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 586 V+ S+ ++ D+ P+ E M +G S Y+ AK + Y YG T Sbjct: 119 AHVLFASSSSVYGDRGNVPLREEMA-DGRVVSP---YAAAKYGAESFCHAYAHLYGYQMT 174 Query: 587 SVIPCNVFGP 616 V+GP Sbjct: 175 IFRYFTVYGP 184 >UniRef50_O06485 Cluster: YfnG; n=3; Bacteria|Rep: YfnG - Bacillus subtilis Length = 301 Score = 48.4 bits (110), Expect = 2e-04 Identities = 50/195 (25%), Positives = 84/195 (43%), Gaps = 5/195 (2%) Frame = +2 Query: 146 TVIERDRQKRNSDYDSETWIFSGSKDGDLRDKTQTEALFAKHKPTHVIHLAAM-VGGLFH 322 T + RD +++ Y E G L D E +++ V HLAA + G+ + Sbjct: 13 TGLVRDHVPQSNLYQGEHIKKMNIVRGSLEDLAVIERALGEYEIDTVFHLAAQAIVGVAN 72 Query: 323 NMAHNLDFFRENMSINDNILQACHKYN-VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPH 499 + + F N+ NIL+AC K+ +K+V+ S + D+ P DE M P Sbjct: 73 R--NPISTFEANILGTWNILEACRKHPLIKRVIVASSDKAYGDQENLPYDENM-----PL 125 Query: 500 SSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPHDNFSLKSSHVIPALIRRM-- 673 Y +K D+++ Y +YG N++G D L + +IP I+ + Sbjct: 126 QGKHPYDVSKSCADLISHTYFHTYGLPVCITRCGNLYGGGD---LNFNRIIPQTIQLVLN 182 Query: 674 DDAMQ-KGDPTFXSD 715 +A + + D TF D Sbjct: 183 GEAPEIRSDGTFVRD 197 >UniRef50_Q5KUQ5 Cluster: UDP-glucose 4-epimerase; n=5; Bacteria|Rep: UDP-glucose 4-epimerase - Geobacillus kaustophilus Length = 323 Score = 47.6 bits (108), Expect = 4e-04 Identities = 35/143 (24%), Positives = 66/143 (46%), Gaps = 2/143 (1%) Frame = +2 Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAA--MVGGLFHNMAHNLDFFRENMSINDNILQACHK 397 GDL +K E +F K+ V+H AA +VG ++ + L +++ N++ +L+ K Sbjct: 48 GDLGNKADLEPIFGKYPIQAVMHFAANSLVG---ESVVNPLKYYQNNVAATLTLLETMLK 104 Query: 398 YNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGC 577 YNVK + + + P E + + P + N Y +K MI+ + + +YG Sbjct: 105 YNVKNFIFSSTAATY----GIPNVELITEDCPTNPIN-PYGRSKLMIEQILADFASAYGL 159 Query: 578 MFTSVIPCNVFGPHDNFSLKSSH 646 + + N G H++ + H Sbjct: 160 NYVVLRYFNAAGAHESGEIGEDH 182 >UniRef50_A5WE41 Cluster: NAD-dependent epimerase/dehydratase; n=5; Bacteria|Rep: NAD-dependent epimerase/dehydratase - Psychrobacter sp. PRwf-1 Length = 357 Score = 47.6 bits (108), Expect = 4e-04 Identities = 34/130 (26%), Positives = 63/130 (48%) Frame = +2 Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 406 D+ D+ E+LFA+H+ V HLAA G+ +++ + + N+ NIL+ C ++NV Sbjct: 79 DIADRAAMESLFAEHQFDAVCHLAAQ-AGVRYSIENPHVYVETNVVGFLNILEGCRQHNV 137 Query: 407 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 586 + S+ ++ + P +T H P S Y+ K+ +++ Y +G T Sbjct: 138 DNLCFASSSSVYGLNQSQPF-KTSDHTDHPVSL---YAATKKSNEMMAHTYAHLFGIRCT 193 Query: 587 SVIPCNVFGP 616 + V+GP Sbjct: 194 GLRFFTVYGP 203 >UniRef50_A0L5P6 Cluster: UDP-glucose 4-epimerase; n=4; Bacteria|Rep: UDP-glucose 4-epimerase - Magnetococcus sp. (strain MC-1) Length = 337 Score = 47.6 bits (108), Expect = 4e-04 Identities = 44/162 (27%), Positives = 71/162 (43%), Gaps = 3/162 (1%) Frame = +2 Query: 224 GDLRDKTQTEALFAKHKPTHVIHLA--AMVGGLFHNMAHNLDFFRENMSINDNILQACHK 397 G L D + LFA+++P VIHLA A VG +M ++R N+ +L+ + Sbjct: 50 GGLDDGAKLAGLFAQYQPQAVIHLAGRAYVG---ESMTDPALYYRNNVQAALVLLECMRQ 106 Query: 398 YNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGC 577 Y K ++ S + + PI E M H N Y +K M + + + Y + YG Sbjct: 107 YGCKNIIFSSSCATYGEHRQMPITEAM----SQHPIN-PYGRSKLMFEWMLQDY-QVYGL 160 Query: 578 MFTSVIPCNVFGPHDNFSLKSSH-VIPALIRRMDDAMQKGDP 700 ++ N G + H P +I R+ +A +KG P Sbjct: 161 QSVALRYFNASGADLEGEIGEQHQPEPHIIPRLLEAARKGSP 202 >UniRef50_A1SL10 Cluster: NAD-dependent epimerase/dehydratase; n=2; Actinomycetales|Rep: NAD-dependent epimerase/dehydratase - Nocardioides sp. (strain BAA-499 / JS614) Length = 346 Score = 46.8 bits (106), Expect = 6e-04 Identities = 49/188 (26%), Positives = 80/188 (42%), Gaps = 17/188 (9%) Frame = +2 Query: 221 DGDLRDKTQTEALFAKHKPTHVIHLAAMVGGL--FHNMAHNLDFFRENM--SINDNILQA 388 +GD+RD L A H++ AA++GG+ FH ++L E + + D ++A Sbjct: 59 EGDVRDLELMADLVADCD--HLVAGAALIGGISYFHTYPYDLLATNERIIAATCDTAIRA 116 Query: 389 CHKYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNES 568 ++KV S+ +F +P E PP S++G+ K ++ R + Sbjct: 117 MPAGRLRKVTYLSSSMVFESTDRWPSKEGDERVIPPPLSSYGFQ--KLAVEYFARAAWDQ 174 Query: 569 YGCMFTSVIPCNVFG------------PHDNFSLKSSHVIPALIRRMDDAMQKGDPT-FX 709 Y +T V P N G P N L SHV+P LI+++ ++ DP Sbjct: 175 YRVPYTIVRPFNCVGVGEGRALGDVEIPSGNIKLAMSHVVPDLIQKV---LRGQDPVHVL 231 Query: 710 SDGEAXNH 733 DG H Sbjct: 232 GDGSQVRH 239 >UniRef50_A2SRX5 Cluster: NAD-dependent epimerase/dehydratase; n=1; Methanocorpusculum labreanum Z|Rep: NAD-dependent epimerase/dehydratase - Methanocorpusculum labreanum (strain ATCC 43576 / DSM 4855 / Z) Length = 307 Score = 46.8 bits (106), Expect = 6e-04 Identities = 38/150 (25%), Positives = 67/150 (44%) Frame = +2 Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 403 G + D+ + H + HLAA V + ++ L N + NIL A ++ Sbjct: 50 GSVTDRPLLAEICKTHSFEGIFHLAA-VASVQKSIEDPLLVHEVNATGTLNILNAAKEHG 108 Query: 404 VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 583 ++KVV S + D +P E M+ P S Y+ +K ++ R + + +G Sbjct: 109 IRKVVLSASAAAYGDNPVFPKREDMLPE--PLSP---YAVSKITAEMYCRNFADLFGVET 163 Query: 584 TSVIPCNVFGPHDNFSLKSSHVIPALIRRM 673 T++ NVFGP + + + + VIP R+ Sbjct: 164 TALRYFNVFGPRQDPNAEYAAVIPKFTERI 193 >UniRef50_Q9FB21 Cluster: Sugar epimerase BlmG; n=1; Streptomyces verticillus|Rep: Sugar epimerase BlmG - Streptomyces verticillus Length = 325 Score = 46.0 bits (104), Expect = 0.001 Identities = 32/132 (24%), Positives = 53/132 (40%), Gaps = 2/132 (1%) Frame = +2 Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 406 DLRD Q A V LAA +GG+ + +N+ I+ + ++AC V Sbjct: 50 DLRDAAQAARAVAG--ADSVFALAANMGGIGWTHTAPAEILHDNLLISTHTIEACRAAGV 107 Query: 407 KKVVSCLSTCIFPDKTTYPIDETMVHNGP--PHSSNFGYSYAKRMIDVLNRGYNESYGCM 580 + V S C++P D + P P + Y + K ++L Y S+G Sbjct: 108 RTTVYTSSACVYPASLQREPDAAPLAEDPVFPAEPDMEYGWEKLTTEILCGAYRRSHGMD 167 Query: 581 FTSVIPCNVFGP 616 + ++GP Sbjct: 168 IKTARLHAIYGP 179 >UniRef50_A5UK04 Cluster: UDP-glucose 4-epimerase; n=2; Euryarchaeota|Rep: UDP-glucose 4-epimerase - Methanobrevibacter smithii (strain PS / ATCC 35061 / DSM 861) Length = 309 Score = 46.0 bits (104), Expect = 0.001 Identities = 39/161 (24%), Positives = 73/161 (45%) Frame = +2 Query: 281 HVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTY 460 ++ HLAAM ++ + N++ +L A NVKKV+ S+ ++ + Sbjct: 72 YIFHLAAMASVPL-SVNDPIKCNDNNVNSTIKLLTAAKNQNVKKVIFSSSSAVYGNNANM 130 Query: 461 PIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPHDNFSLKS 640 P+ E+ + P S Y+ +K ++ + + ESYG ++ NVFGP + + + Sbjct: 131 PLKESELMM--PTSP---YAASKANCELYLQAFEESYGLKSIALRYFNVFGPKQDKNSQY 185 Query: 641 SHVIPALIRRMDDAMQKGDPTFXSDGEAXNHSDSLFIHXIS 763 + VIP I D + P DG+ D +F+ ++ Sbjct: 186 AAVIPNFI---DAILNNEHPIIYGDGQQTR--DFIFVKDVA 221 >UniRef50_Q0W7F9 Cluster: Putative UDP-glucose 4-epimerase; n=1; uncultured methanogenic archaeon RC-I|Rep: Putative UDP-glucose 4-epimerase - Uncultured methanogenic archaeon RC-I Length = 306 Score = 45.6 bits (103), Expect = 0.001 Identities = 36/129 (27%), Positives = 60/129 (46%) Frame = +2 Query: 284 VIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTYP 463 V HLAA + + ++ + + F N N+L+ K VKK V S ++ P Sbjct: 70 VYHLAA-ISNVDASIRNPIRTFETNAMGTANVLEEARKAGVKKFVYVSSAHVYGVPQYLP 128 Query: 464 IDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPHDNFSLKSS 643 IDE H P + Y+ +K + + + Y SYG + + P N+FGP + S Sbjct: 129 IDEK--HPVVPREA---YAASKIAAENIVQAYGNSYGIEYAILRPFNIFGPGQD----PS 179 Query: 644 HVIPALIRR 670 +IP +I++ Sbjct: 180 FLIPGVIKQ 188 >UniRef50_Q9ABX8 Cluster: UDP-glucose 4-epimerase; n=1; Caulobacter vibrioides|Rep: UDP-glucose 4-epimerase - Caulobacter crescentus (Caulobacter vibrioides) Length = 327 Score = 45.2 bits (102), Expect = 0.002 Identities = 32/117 (27%), Positives = 55/117 (47%) Frame = +2 Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 403 GD+RD + +A+FA + P V+H AA + + ++ + FF N+ +++A + Sbjct: 50 GDIRDAARLDAVFAAYAPVAVLHFAARI-EVGESVKNPGAFFDTNVGGTITLIEAARRAG 108 Query: 404 VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYG 574 VK VV + F D P+ ET H P + Y +K M++ Y+ G Sbjct: 109 VKVVVFSSTCATFGDPVDLPMKET--H---PQAPLNPYGRSKLMVEQALADYDRYVG 160 >UniRef50_Q70PA0 Cluster: Putative uncharacterized protein; n=1; Melittangium lichenicola|Rep: Putative uncharacterized protein - Melittangium lichenicola Length = 320 Score = 45.2 bits (102), Expect = 0.002 Identities = 31/130 (23%), Positives = 59/130 (45%) Frame = +2 Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 406 D+RD LF +P V+HLAA VG + + + ++ N++ +L+ C + V Sbjct: 61 DIRDAKACRELFDGARPERVVHLAARVGVRTLD-SESPEYAETNVTGFLQVLELCRRSRV 119 Query: 407 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 586 + +V S+ ++ + P E + P Y+ KR +++ Y+ Y T Sbjct: 120 EHLVFASSSSVYGAGSDMPFSEDSAADRPLSL----YAATKRANEMMAHAYSHQYAMPIT 175 Query: 587 SVIPCNVFGP 616 + +V+GP Sbjct: 176 GLRLFSVYGP 185 >UniRef50_Q9KDV3 Cluster: UDP-glucose 4-epimerase; n=124; cellular organisms|Rep: UDP-glucose 4-epimerase - Bacillus halodurans Length = 334 Score = 45.2 bits (102), Expect = 0.002 Identities = 37/155 (23%), Positives = 69/155 (44%), Gaps = 7/155 (4%) Frame = +2 Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAA--MVGGLFHNMAHNLDFFRENMSINDNILQACHK 397 GD+RD + +F H VIH AA +VG ++ ++++ N+ +L+ + Sbjct: 49 GDIRDDQLLDTIFTTHSIDTVIHFAANSLVG---ESVKQPIEYYENNVIGTHTLLKKMLE 105 Query: 398 YNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGC 577 ++VKK+V + + + PI E + P +N Y K I+ + E+YG Sbjct: 106 HDVKKIVFSSTAATYGEPVQIPIQE----SDPTIPTN-PYGETKLAIEKMFHWCQEAYGL 160 Query: 578 MFTSVIPCNVFGPHDNFSL-----KSSHVIPALIR 667 + + N G N + SH+IP +++ Sbjct: 161 QYVCLRYFNAAGADPNGRIGEDHSPESHLIPIVLQ 195 >UniRef50_Q832Q5 Cluster: NAD-dependent epimerase/dehydratase family protein; n=6; Lactobacillales|Rep: NAD-dependent epimerase/dehydratase family protein - Enterococcus faecalis (Streptococcus faecalis) Length = 324 Score = 44.8 bits (101), Expect = 0.003 Identities = 40/183 (21%), Positives = 86/183 (46%), Gaps = 3/183 (1%) Frame = +2 Query: 221 DGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKY 400 +G + D+ E + +++ ++ HLAA + + ++A ++ + N +L+ KY Sbjct: 54 EGSVTDQQLMEKVLQEYQFDYIFHLAA-IASVADSVARPVETHQVNFESVLQLLELIRKY 112 Query: 401 --NVKKVVSCLSTCIFPDKTTYPI-DETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESY 571 ++K++V S ++ D+ T P +E+++ P++ + +A VLN Y Y Sbjct: 113 QKDLKRLVFASSAAVYGDEPTLPKQEESVIRPLTPYAVD---KFASEKY-VLN--YCHLY 166 Query: 572 GCMFTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDPTFXSDGEAXNHSDSLFI 751 ++V NV+GP+ N + S VI ++ + + TF G+ D +F+ Sbjct: 167 DVPTSAVRFFNVYGPNQNPNSPYSGVISIVMDSYKRLLANQEVTFNIFGDGKQSRDFVFV 226 Query: 752 HXI 760 + Sbjct: 227 EDV 229 >UniRef50_O54385 Cluster: UDP-glucose epimerase; n=11; cellular organisms|Rep: UDP-glucose epimerase - Brucella abortus Length = 335 Score = 44.8 bits (101), Expect = 0.003 Identities = 38/135 (28%), Positives = 58/135 (42%), Gaps = 1/135 (0%) Frame = +2 Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 403 GD+RD+ E + +HK T VIH A + + + L ++ N+ +LQA Sbjct: 57 GDIRDRALMEQVIKRHKCTAVIHFAGL-KAVGESSEKPLLYYDCNVLGTLRLLQAMEATG 115 Query: 404 VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMI-DVLNRGYNESYGCM 580 VKK+V S ++ D PI E P S+ Y K +I D+L YN Sbjct: 116 VKKLVFSSSATVYGDPDKLPITEDQ-----PLSATNPYGRTKLVIEDMLRDLYNSDNSWA 170 Query: 581 FTSVIPCNVFGPHDN 625 + N G H++ Sbjct: 171 IAILRYFNPVGAHES 185 >UniRef50_A6CLM3 Cluster: UDP-glucose 4-epimerase; n=1; Bacillus sp. SG-1|Rep: UDP-glucose 4-epimerase - Bacillus sp. SG-1 Length = 306 Score = 44.8 bits (101), Expect = 0.003 Identities = 43/165 (26%), Positives = 71/165 (43%) Frame = +2 Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 406 ++ DK + +F K +P VIH+AA V M +D N+ N+L C KY V Sbjct: 50 NITDKNLSN-VFDKERPDAVIHMAAQVDVSRSVMEPIMDA-EVNILGTINVLNECVKYKV 107 Query: 407 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 586 KKVV ++ ++ + I E N +F Y +K ++ + + +G +T Sbjct: 108 KKVVYSSTSAVYGENVASEISE----NEKIMPISF-YGISKYTPELYLEAFFKIHGLKYT 162 Query: 587 SVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDPTFXSDGE 721 + NV+G + VIP I + M+ P DG+ Sbjct: 163 ILRYSNVYGERQGIKGEGG-VIPIFIHEL---MEDRSPVIFGDGK 203 >UniRef50_O28263 Cluster: UDP-glucose 4-epimerase; n=1; Archaeoglobus fulgidus|Rep: UDP-glucose 4-epimerase - Archaeoglobus fulgidus Length = 307 Score = 44.8 bits (101), Expect = 0.003 Identities = 36/112 (32%), Positives = 58/112 (51%) Frame = +2 Query: 257 LFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTC 436 +F KH+ VIH AA + + +H +D FR N+ NIL+AC ++V+KVV S Sbjct: 50 VFRKHEIEGVIHAAAELS-VKAEKSH-VDAFRANVEGALNILEACRVFDVEKVVFTSSHS 107 Query: 437 IFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSV 592 ++ + +YP E + P + F Y K ++L Y+ +YG F +V Sbjct: 108 VYGPR-SYPFTE-FSYRDP---TTF-YGATKACSEILGTYYSYTYGIDFRAV 153 >UniRef50_A3ERU6 Cluster: Nucleoside-diphosphate-sugar epimerase; n=2; Bacteria|Rep: Nucleoside-diphosphate-sugar epimerase - Leptospirillum sp. Group II UBA Length = 316 Score = 44.4 bits (100), Expect = 0.003 Identities = 42/166 (25%), Positives = 79/166 (47%) Frame = +2 Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 403 GD+R E A T V H AA VG + ++A D N++ N+L ++ Sbjct: 53 GDVRSFADIEK--ALEGVTFVFHQAA-VGSVPRSIADPFDTQTANVNGTLNLLWKAKEFG 109 Query: 404 VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 583 V++VV S+ ++ D P ET++ + P S Y+ +K ++ + +++++G Sbjct: 110 VQRVVIAGSSSVYGDTPGMPRVETLLPS--PLSP---YALSKLSQELFGKIFSKTFGLDT 164 Query: 584 TSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDPTFXSDGE 721 ++ N+FGP + + + VIP +R + ++K T GE Sbjct: 165 VTLRYFNIFGPRQDPRSEYAAVIPRFVRAI---LKKDAVTINGTGE 207 >UniRef50_Q8R8R8 Cluster: UDP-glucose 4-epimerase; n=15; Bacteria|Rep: UDP-glucose 4-epimerase - Thermoanaerobacter tengcongensis Length = 329 Score = 44.0 bits (99), Expect = 0.004 Identities = 41/176 (23%), Positives = 82/176 (46%), Gaps = 11/176 (6%) Frame = +2 Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAA--MVGGLFHNMAHNLDFFRENMSINDNILQACHK 397 GDLRD+ + +F+++ V+H AA +VG ++ + ++ N+ ++L+A K Sbjct: 49 GDLRDEDFLDKVFSENDIEAVMHFAASSLVG---ESVENPFKYYENNVCGTLSLLKAMKK 105 Query: 398 YNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGC 577 + VKK+V + ++ + PI+E +N Y K I+ + + + +YG Sbjct: 106 HGVKKIVFSSTAAVYGEPERIPIEE----EDRTEPTN-PYGETKLAIEKMLKWADAAYGI 160 Query: 578 MFTSVIPCNVFGPHDNFSL-----KSSHVIPALIR----RMDDAMQKGDPTFXSDG 718 + ++ NV G + + +H+IP +++ + D M GD DG Sbjct: 161 KYVALRYFNVAGALETGEIGEDHSPETHLIPIILQVALGKRDKVMIYGDDYPTKDG 216 >UniRef50_Q83W21 Cluster: Ata17 protein; n=9; Bacteria|Rep: Ata17 protein - Streptomyces capreolus Length = 384 Score = 44.0 bits (99), Expect = 0.004 Identities = 37/147 (25%), Positives = 57/147 (38%), Gaps = 2/147 (1%) Frame = +2 Query: 284 VIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFP--DKTT 457 V LAA +GG+ A++ + N I+ N L+A K V + S C++P + Sbjct: 115 VYSLAADMGGMGFISANHATIMKNNSLIDLNTLEAARKARVNRFFYASSACVYPAYRQNI 174 Query: 458 YPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPHDNFSLK 637 + + P + GY + K + L Y E YG NV+GP+ + Sbjct: 175 TEVVGLREEDAYPAAPEDGYGWEKLNTEHLCSYYREEYGLPVRVARLHNVYGPYCTYDGG 234 Query: 638 SSHVIPALIRRMDDAMQKGDPTFXSDG 718 AL R+ A G DG Sbjct: 235 REKSPAALARKAALAEPGGRMEIWGDG 261 >UniRef50_Q9WYX9 Cluster: UDP-glucose 4-epimerase, putative; n=5; Thermotogaceae|Rep: UDP-glucose 4-epimerase, putative - Thermotoga maritima Length = 309 Score = 43.6 bits (98), Expect = 0.006 Identities = 35/134 (26%), Positives = 59/134 (44%), Gaps = 2/134 (1%) Frame = +2 Query: 230 LRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVK 409 + D+ E +F+ H+P +V HLAA D + N+ + +L+ KY VK Sbjct: 52 IEDEEMMERIFSLHRPEYVFHLAAQASVAISVREPARD-AKTNIIGSLVLLEKSIKYGVK 110 Query: 410 K-VVSCLSTCIFPDKT-TYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 583 K + S I+ + +P ET + PH + Y AK ++ + YG + Sbjct: 111 KFIFSSTGGAIYGENVKVFPTPETEI----PHPIS-PYGIAKYSTEMYLEFFAREYGLKY 165 Query: 584 TSVIPCNVFGPHDN 625 T + NV+GP + Sbjct: 166 TVLRYANVYGPRQD 179 >UniRef50_Q0C2X5 Cluster: UDP-glucose 4-epimerase; n=1; Hyphomonas neptunium ATCC 15444|Rep: UDP-glucose 4-epimerase - Hyphomonas neptunium (strain ATCC 15444) Length = 335 Score = 43.6 bits (98), Expect = 0.006 Identities = 31/120 (25%), Positives = 56/120 (46%), Gaps = 2/120 (1%) Frame = +2 Query: 221 DGDLRDKTQTEALFAKHKPTHVIHLAA--MVGGLFHNMAHNLDFFRENMSINDNILQACH 394 +GDL EA F+ KP V H AA +VG ++ ++R N N+L A Sbjct: 50 EGDLNSPGDIEAAFSAIKPDAVAHFAASTLVG---ESVTEPGKYYRNNTFTTLNVLDAMQ 106 Query: 395 KYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYG 574 ++N + ++ + IF T E + + P + N Y +K M++ + G++ ++G Sbjct: 107 RHNTRAIIFSSTCAIFGHAQT----EFLAEDHPKNPIN-PYGMSKLMVEQMLAGFDHAHG 161 >UniRef50_A7HI28 Cluster: NAD-dependent epimerase/dehydratase; n=9; Bacteria|Rep: NAD-dependent epimerase/dehydratase - Anaeromyxobacter sp. Fw109-5 Length = 373 Score = 43.6 bits (98), Expect = 0.006 Identities = 32/131 (24%), Positives = 59/131 (45%), Gaps = 1/131 (0%) Frame = +2 Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRE-NMSINDNILQACHKYN 403 D+ D+ +A+ + +P +V+HLAA VG N N + E N+ N+L C + Sbjct: 103 DVADREALDAVLDEAEPEYVVHLAAQVG--VRNSVRNPRAYAETNLDGFFNVLDGCARRG 160 Query: 404 VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 583 V+ +V S+ ++ P E + H +F Y+ K+ +++ Y+ Sbjct: 161 VRHLVYASSSSVYGSNEKVPFSE---EDPVDHPISF-YAATKKANEIMAHAYSHLNRLPT 216 Query: 584 TSVIPCNVFGP 616 T + V+GP Sbjct: 217 TGLRFFTVYGP 227 >UniRef50_Q8TXF0 Cluster: Nucleoside-diphosphate-sugar epimerase; n=1; Methanopyrus kandleri|Rep: Nucleoside-diphosphate-sugar epimerase - Methanopyrus kandleri Length = 309 Score = 43.6 bits (98), Expect = 0.006 Identities = 49/181 (27%), Positives = 81/181 (44%), Gaps = 2/181 (1%) Frame = +2 Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 406 D+ D E F +++P VIHLAA V + ++M R N N++ +++V Sbjct: 53 DVTDPRAVERTFREYRPEAVIHLAAQV-NVRYSMESPFVDARINALGTLNLVSLAAEHDV 111 Query: 407 KKVVSCLS-TCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 583 ++ V S ++ + P+DE H P SN+G S K + R Y E G + Sbjct: 112 ERFVYASSGGAVYGEPEYLPVDEE--HPTRP-ISNYGVS--KLAGEYYVRVYAERDGFEY 166 Query: 584 TSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDP-TFXSDGEAXNHSDSLFIHXI 760 + NV+GP + + VIP + R +G+P T DGE D +F+ + Sbjct: 167 VILRYANVYGPRQD-PRGEAGVIPIFLLR----AARGEPLTIFGDGEQTR--DFVFVEDV 219 Query: 761 S 763 + Sbjct: 220 A 220 >UniRef50_Q8THP9 Cluster: DTDP-glucose 4,6-dehydratase; n=3; Methanosarcina|Rep: DTDP-glucose 4,6-dehydratase - Methanosarcina acetivorans Length = 298 Score = 43.2 bits (97), Expect = 0.008 Identities = 42/149 (28%), Positives = 66/149 (44%) Frame = +2 Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 403 GD+ D + E A V H AA+V + ++ FR N N+LQAC + Sbjct: 52 GDICDPSSVEK--AVSGMDCVFHEAALVSVPL-SCEKPVEAFRINTLGTLNVLQACVRAG 108 Query: 404 VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 583 V+K V+ S ++ + P E M P +S Y+ +K + L R + E +G Sbjct: 109 VEKFVTASSAAVYGNNPELPKRENMY---PEPAS--PYAISKLDGEYLARMFYEEHGLRT 163 Query: 584 TSVIPCNVFGPHDNFSLKSSHVIPALIRR 670 T + NV+GP + + VIP + R Sbjct: 164 TCLRYFNVYGPRQDPKSPYAAVIPIFLER 192 >UniRef50_Q9RWF7 Cluster: UDP-glucose 4-epimerase, putative; n=63; cellular organisms|Rep: UDP-glucose 4-epimerase, putative - Deinococcus radiodurans Length = 344 Score = 42.7 bits (96), Expect = 0.010 Identities = 37/150 (24%), Positives = 64/150 (42%) Frame = +2 Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 403 GD+RD AL + V HLAA++ + +A + N++ N+L+A Sbjct: 74 GDVRDAGSVRALMRDVQT--VYHLAALIAIPYSYVAPR-SYVETNITGTLNVLEAARDLG 130 Query: 404 VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 583 +V+ ++ ++ + PI H P YS K D L Y S+G Sbjct: 131 TGRVIHTSTSEVYGTARSVPI-----HESHPLQGQSPYSATKIGADKLAESYFLSFGLPV 185 Query: 584 TSVIPCNVFGPHDNFSLKSSHVIPALIRRM 673 ++ P N +GP + + VIP +I ++ Sbjct: 186 VTLRPFNTYGPRQS----ARAVIPTIISQL 211 >UniRef50_Q6MF46 Cluster: Probable UDP-glucuronat epimerase; n=2; cellular organisms|Rep: Probable UDP-glucuronat epimerase - Protochlamydia amoebophila (strain UWE25) Length = 327 Score = 42.7 bits (96), Expect = 0.010 Identities = 28/132 (21%), Positives = 64/132 (48%) Frame = +2 Query: 221 DGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKY 400 +GD+++ + + H+ TH+IHLAA G+ +++ + + N+ NIL+ C + Sbjct: 69 EGDIQNYEKLQNSILLHQTTHLIHLAAQ-AGVRYSLQEPATYLKTNVDGFLNILEICRSH 127 Query: 401 NVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 580 K++ S+ ++ T P ++ +S +G + K+ +++ + Y+ +G Sbjct: 128 PHLKLIYASSSSVYGLNTKVPF--SLEDRTDQQASLYGVT--KKTNELMAKTYHHLFGIS 183 Query: 581 FTSVIPCNVFGP 616 + V+GP Sbjct: 184 SIGLRFFTVYGP 195 >UniRef50_Q9JRN7 Cluster: Putative uncharacterized protein; n=1; Aggregatibacter actinomycetemcomitans|Rep: Putative uncharacterized protein - Actinobacillus actinomycetemcomitans (Haemophilusactinomycetemcomitans) Length = 294 Score = 42.7 bits (96), Expect = 0.010 Identities = 44/181 (24%), Positives = 79/181 (43%), Gaps = 2/181 (1%) Frame = +2 Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 406 DL + +++ K KP ++HLAA+ F + + F+ N +N+L++ NV Sbjct: 38 DLTNPCSVQSVLEKTKPDFIVHLAALT---FVPNNNPITFYLVNTIGTENLLRSIVDLNV 94 Query: 407 KKV-VSCLSTC-IFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 580 K+ V C ST I+ + T + E++ H YS +K ++ + Y G Sbjct: 95 AKLGVLCFSTAGIYGIQETKLLSESLTPKPVNH-----YSMSKHCMEHIVNKYRCFRG-- 147 Query: 581 FTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDPTFXSDGEAXNHSDSLFIHXI 760 T V P NV G N + ++ A +++ D ++ G+ D + N + I Sbjct: 148 ITVVRPFNVLGLGQNINFLVPKMVSAFVKK-DKTIELGNLDSVRDFISVNDCCDIIYRLI 206 Query: 761 S 763 S Sbjct: 207 S 207 >UniRef50_A3PE63 Cluster: UDP-glucose 4-epimerase; n=1; Prochlorococcus marinus str. MIT 9301|Rep: UDP-glucose 4-epimerase - Prochlorococcus marinus (strain MIT 9301) Length = 330 Score = 42.7 bits (96), Expect = 0.010 Identities = 35/157 (22%), Positives = 72/157 (45%), Gaps = 5/157 (3%) Frame = +2 Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 406 D+R+++ + L K KP +++H AA + ++ LD+ N+ ++ + C + + Sbjct: 53 DIREESSFKELLLKIKPDYLVHFAAS-AYVSESIFKPLDYISNNIDGMRSVCKICSEIKI 111 Query: 407 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 586 V S S ++ + PI+E+ N P S Y K + + + + +YG + Sbjct: 112 PIVFSS-SCSVYGEAKNVPINESEPLN--PLSP---YGETKLFCEKILKWCSNAYGLRWV 165 Query: 587 SVIPCNVFGPHDNFSL-----KSSHVIPALIRRMDDA 682 S+ N G ++ + +H+IP IR + D+ Sbjct: 166 SLRYFNAAGADEDLEIGEKHDPETHIIPLAIRALGDS 202 >UniRef50_Q9YCT1 Cluster: DTDP-glucose 4,6-dehydratase; n=2; Thermoprotei|Rep: DTDP-glucose 4,6-dehydratase - Aeropyrum pernix Length = 330 Score = 42.7 bits (96), Expect = 0.010 Identities = 36/139 (25%), Positives = 64/139 (46%), Gaps = 1/139 (0%) Frame = +2 Query: 212 GSKDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQAC 391 G GD+ D+ Q + + +P V++ AA + ++ F R N+ IL+A Sbjct: 51 GFMRGDIADEEQFGRVLTEFEPDVVVNFAAETH-VDRSINEPAPFMRTNIIGVFTILEAI 109 Query: 392 HKYNVKKVVSCLSTC-IFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNES 568 K + V+ +ST ++ D + T P + + YS +K D+L + Y + Sbjct: 110 RKRIDQIVLLHVSTDEVYGDLWNTGKEAT---ESDPLNPSSPYSASKASGDLLIKAYGRT 166 Query: 569 YGCMFTSVIPCNVFGPHDN 625 YG + V PCN +GP+ + Sbjct: 167 YGLKYRIVRPCNNYGPYQH 185 >UniRef50_A7CY79 Cluster: NAD-dependent epimerase/dehydratase; n=1; Opitutaceae bacterium TAV2|Rep: NAD-dependent epimerase/dehydratase - Opitutaceae bacterium TAV2 Length = 349 Score = 42.3 bits (95), Expect = 0.014 Identities = 32/145 (22%), Positives = 57/145 (39%) Frame = +2 Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 406 D+RD E FA H P H ++ A G+ ++ + N+ N+L+AC ++V Sbjct: 79 DIRDPAAIERTFATHHPIHAVYHLAARAGVRPSIHSPRLYLSTNIDGTLNLLEACRAHHV 138 Query: 407 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 586 + S+ ++ P ET P + Y+ +K + L Y +G Sbjct: 139 PDFILASSSSVYGANPKTPFAET----DPIQRTLSPYAASKLAAEQLCSNYAHLHGLRCL 194 Query: 587 SVIPCNVFGPHDNFSLKSSHVIPAL 661 + V+GP L + A+ Sbjct: 195 CLRLFTVYGPRQRPDLAIARFTAAI 219 >UniRef50_Q2SII8 Cluster: Nucleoside-diphosphate-sugar epimerase; n=3; Gammaproteobacteria|Rep: Nucleoside-diphosphate-sugar epimerase - Hahella chejuensis (strain KCTC 2396) Length = 319 Score = 41.9 bits (94), Expect = 0.018 Identities = 35/130 (26%), Positives = 59/130 (45%), Gaps = 3/130 (2%) Frame = +2 Query: 236 DKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKV 415 +K E +F KH T VIHL M+ + M + N+ + +L CHKY+++KV Sbjct: 58 NKRGFEDIFRKHNITGVIHLGRMIASEENRMRR----YNSNVLGSHRLLDLCHKYHIQKV 113 Query: 416 VSCLSTCIFPDKTTYPIDETMVHNGPP-HSSNFGYSYAKRM-IDVLNRGYNESYGCMFTS 589 + LST Y + ++ G P ++ + ++ L Y Y + + Sbjct: 114 I-ILSTYHVYGANAY--NPALIDEGAPLKAAELTMDLIDSVELENLANIYLWKYPDLNIT 170 Query: 590 VI-PCNVFGP 616 V+ PCN+ GP Sbjct: 171 VLRPCNIVGP 180 >UniRef50_Q12UG3 Cluster: NAD-dependent epimerase/dehydratase; n=2; Euryarchaeota|Rep: NAD-dependent epimerase/dehydratase - Methanococcoides burtonii (strain DSM 6242) Length = 299 Score = 41.9 bits (94), Expect = 0.018 Identities = 38/146 (26%), Positives = 59/146 (40%) Frame = +2 Query: 284 VIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTYP 463 +IH AA + + +M + N+ N+L+ N+++ V S + + P Sbjct: 66 IIHTAAQIS-VVRSMNEPFFDAQNNIMGTLNLLEEARHANIERFVYFSSAATYGNPLKVP 124 Query: 464 IDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPHDNFSLKSS 643 I ET H P S A ++ YN++YG T + P N++ P + S S Sbjct: 125 IGET--HPQEPLSPYGASKLAGEKYCIM---YNKAYGLPTTCIRPFNIYSPRQDPSNPYS 179 Query: 644 HVIPALIRRMDDAMQKGDPTFXSDGE 721 VI I D PT DGE Sbjct: 180 GVISKFI---DKVSGGASPTIFGDGE 202 >UniRef50_Q661H6 Cluster: Nucleotide sugar epimerase; n=3; Borrelia burgdorferi group|Rep: Nucleotide sugar epimerase - Borrelia garinii Length = 355 Score = 41.5 bits (93), Expect = 0.024 Identities = 32/133 (24%), Positives = 63/133 (47%), Gaps = 2/133 (1%) Frame = +2 Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQAC--HKY 400 D+ +K + LF ++K THV HLAA G+ ++ + + N+ N+L C +K Sbjct: 76 DILNKDKLLKLFKEYKFTHVCHLAAQ-AGIRDSLENPDSYVSINIVGFFNVLDVCRVYKE 134 Query: 401 NVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 580 N+K V ++ ++ P E + + H N Y+ +K+ +++ Y+ S+ Sbjct: 135 NIKHFVYASTSSVYGINENIPSSEDSITD---HPLNL-YAASKKSNEMIAHAYSASFNIP 190 Query: 581 FTSVIPCNVFGPH 619 T + V+G + Sbjct: 191 TTGLRFFTVYGTY 203 >UniRef50_Q0YI68 Cluster: NAD-dependent epimerase/dehydratase:Short-chain dehydrogenase/reductase SDR:3-beta hydroxysteroid dehydrogenase/isomerase:Polysaccharide biosynthesis protein CapD:dTDP- 4-dehydrorhamnose reductase:Nucleotide sugar epimerase; n=3; cellular organisms|Rep: NAD-dependent epimerase/dehydratase:Short-chain dehydrogenase/reductase SDR:3-beta hydroxysteroid dehydrogenase/isomerase:Polysaccharide biosynthesis protein CapD:dTDP- 4-dehydrorhamnose reductase:Nucleotide sugar epimerase - Geobacter sp. FRC-32 Length = 328 Score = 41.5 bits (93), Expect = 0.024 Identities = 33/144 (22%), Positives = 62/144 (43%) Frame = +2 Query: 221 DGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKY 400 +GD+RD+ A+F + P VIHLAA G+ ++ + L + N+ N+L+A Sbjct: 64 EGDIRDEEFIRAIFTQELPDAVIHLAA-AAGVRPSIDNPLLYEEVNVRGTMNLLEAAKAI 122 Query: 401 NVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 580 V+ + S+ ++ + P E P + Y+ K+ +++ Y+ Y Sbjct: 123 GVRLFLFASSSSVYGNNPKVPFAEA----DPVDNPISPYAATKKAGELICHTYHHLYDIN 178 Query: 581 FTSVIPCNVFGPHDNFSLKSSHVI 652 + V+GP L S + Sbjct: 179 IACLRFFTVYGPRQRPDLAISKFV 202 >UniRef50_Q5FQW6 Cluster: UDP-glucose 4-epimerase; n=3; Bacteria|Rep: UDP-glucose 4-epimerase - Gluconobacter oxydans (Gluconobacter suboxydans) Length = 328 Score = 41.1 bits (92), Expect = 0.032 Identities = 32/99 (32%), Positives = 50/99 (50%), Gaps = 5/99 (5%) Frame = +2 Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAM--VGGLFHNMAHNLDFFRENMSINDNILQACHKY 400 DL D T A+ A+ K V+H AA+ VG + H + R+N N++Q C ++ Sbjct: 51 DLLDYAATSAVVAQGKWDGVLHFAALSLVGDSMRDPFH---YLRQNYLTALNLVQICVEH 107 Query: 401 NVKKVVSCLSTCIF--PDKTTYPIDETM-VHNGPPHSSN 508 VKK+V + +F P++ PI ET V G P+ + Sbjct: 108 GVKKIVFSSTAALFGGPERLD-PIPETAPVQPGSPYGES 145 >UniRef50_A6PV21 Cluster: UDP-glucose 4-epimerase; n=1; Victivallis vadensis ATCC BAA-548|Rep: UDP-glucose 4-epimerase - Victivallis vadensis ATCC BAA-548 Length = 307 Score = 41.1 bits (92), Expect = 0.032 Identities = 42/174 (24%), Positives = 77/174 (44%), Gaps = 9/174 (5%) Frame = +2 Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAA--MVGGLFHNMAHNLDFFRENMSINDNILQACHK 397 G+L D+ + +++ + K ++H AA +VG +M +FR N++ N+ A + Sbjct: 34 GNLSDREKIKSVCREGKFDAIMHFAAFSLVG---ESMKDPSKYFRNNIANGINLADAAVE 90 Query: 398 YNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGC 577 VK V + F + PI E P + Y +K + + + Y+E YG Sbjct: 91 SGVKMFVFSSTAATFGQPESIPIKE--FDRQIPINP---YGESKLCFEKILKWYHEIYGI 145 Query: 578 MFTSVIPCNVFGPHDNFS---LKSSHVIPALIR----RMDDAMQKGDPTFXSDG 718 + ++ N G +NF +H+IP +++ + D M GD +DG Sbjct: 146 NYAALRYFNAAGATENFGEDHRPETHLIPLILQTVRGKRDKLMLYGDDYDTADG 199 >UniRef50_A0B5G2 Cluster: NAD-dependent epimerase/dehydratase; n=2; Methanomicrobia|Rep: NAD-dependent epimerase/dehydratase - Methanosaeta thermophila (strain DSM 6194 / PT) (Methanothrixthermophila (strain DSM 6194 / PT)) Length = 310 Score = 41.1 bits (92), Expect = 0.032 Identities = 39/147 (26%), Positives = 66/147 (44%) Frame = +2 Query: 281 HVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTY 460 +V+H AA+ + ++ + R N+ ++L A VK+VV S+ ++ D Sbjct: 72 YVLHQAALPS-VQRSIMDPMATNRSNIDGTLSVLVAAMDCGVKRVVFASSSAVYGDSPEL 130 Query: 461 PIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPHDNFSLKS 640 P E+++ P S Y+ K + + R + E YG S+ NVFGP + + + Sbjct: 131 PKRESLIPR--PMSP---YAVTKLVGEHYCRVFYEIYGIECVSLRYFNVFGPGQDPASEY 185 Query: 641 SHVIPALIRRMDDAMQKGDPTFXSDGE 721 + VIP I D + P DGE Sbjct: 186 AAVIPKFI---DAVLSGSQPVVYGDGE 209 >UniRef50_Q9LIS3 Cluster: UDP-glucuronate 4-epimerase 6; n=40; Viridiplantae|Rep: UDP-glucuronate 4-epimerase 6 - Arabidopsis thaliana (Mouse-ear cress) Length = 460 Score = 41.1 bits (92), Expect = 0.032 Identities = 34/133 (25%), Positives = 57/133 (42%), Gaps = 1/133 (0%) Frame = +2 Query: 221 DGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKY 400 +GDL D LF TH++HLAA G+ + M + + N++ N+L+ Sbjct: 169 EGDLNDGPLLRKLFDVVPFTHILHLAAQ-AGVRYAMKNPQSYIASNIAGFVNLLEVAKAA 227 Query: 401 NVK-KVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGC 577 N + +V S+ ++ T P E + P Y+ K+ + + YN YG Sbjct: 228 NPQPAIVWASSSSVYGLNTENPFSEEHRTDQPASL----YAATKKAGEEIAHTYNHIYGL 283 Query: 578 MFTSVIPCNVFGP 616 T + V+GP Sbjct: 284 SLTGLRFFTVYGP 296 >UniRef50_P72903 Cluster: UDP-glucose-4-epimerase; n=20; Bacteria|Rep: UDP-glucose-4-epimerase - Synechocystis sp. (strain PCC 6803) Length = 340 Score = 40.7 bits (91), Expect = 0.042 Identities = 34/161 (21%), Positives = 73/161 (45%), Gaps = 1/161 (0%) Frame = +2 Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 403 GDL D + +F +H+ V+H A + + ++ H L+++ N S ++++ C + Sbjct: 55 GDLADTERLHQVFHEHEILAVMHFAGSL-IVPESLIHPLNYYANNTSNTLSLIRCCQIFG 113 Query: 404 VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 583 V +++ + ++ + ++ PI E + P N Y +K + + + Y +S + Sbjct: 114 VNRLIFSSTAAVYGNSSSNPISEAEI----PCPIN-PYGRSKLASEWIIQDYAKSSALQY 168 Query: 584 TSVIPCNVFGPHDNFSL-KSSHVIPALIRRMDDAMQKGDPT 703 + NV G L + S L+R + DA+ P+ Sbjct: 169 VILRYFNVAGADPEGRLGQMSKTTTHLVRSVCDAILNLKPS 209 >UniRef50_Q1VUQ5 Cluster: Sugar epimerase BlmG; n=2; Bacteria|Rep: Sugar epimerase BlmG - Psychroflexus torquis ATCC 700755 Length = 359 Score = 40.7 bits (91), Expect = 0.042 Identities = 35/156 (22%), Positives = 59/156 (37%), Gaps = 7/156 (4%) Frame = +2 Query: 170 KRNSDYDSETWIFSGSKDGDLRDKTQTEALFAKHKPT---HVIHLAAMVGGLFHNMA--H 334 K N ++ I +GDLRD E F + V LAA +GG + + Sbjct: 34 KPNHEFWDHQLICDEYMEGDLRDPRIVEKAFENKQNVSYDEVYQLAADMGGALYIFTGEN 93 Query: 335 NLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSN-- 508 + + + IN N+ C K + +V S C++P+ D + +N Sbjct: 94 DANVMHNSALINLNVAHECVKNKIGRVFYSSSACMYPEHNQLDADNPNCEESSAYPANPD 153 Query: 509 FGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGP 616 Y + K + L ++ +Y N+FGP Sbjct: 154 SEYGWEKLFSERLFLAFSRNYKLSVRVARFHNIFGP 189 >UniRef50_A4CBV8 Cluster: NAD dependent epimerase/dehydratase family protein; n=4; Proteobacteria|Rep: NAD dependent epimerase/dehydratase family protein - Pseudoalteromonas tunicata D2 Length = 332 Score = 40.3 bits (90), Expect = 0.055 Identities = 32/130 (24%), Positives = 57/130 (43%) Frame = +2 Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 406 DL D+ LFA + VIHLAA G+ +++ + + + N+ IL+ C V Sbjct: 61 DLADREAIANLFATEQFERVIHLAAQ-AGVRYSIENPMAYIDSNLVGMATILEGCRHNKV 119 Query: 407 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFT 586 + +V S+ ++ T P E + P Y+ K+ +++ Y+ Y T Sbjct: 120 QHLVYASSSSVYGANTKIPFAEEDRVDYPVSL----YAATKKSNELMAHTYSHLYSLPTT 175 Query: 587 SVIPCNVFGP 616 + V+GP Sbjct: 176 GLRFFTVYGP 185 >UniRef50_O26473 Cluster: DTDP-glucose 4,6-dehydratase related protein; n=2; Methanobacteriaceae|Rep: DTDP-glucose 4,6-dehydratase related protein - Methanobacterium thermoautotrophicum Length = 334 Score = 40.3 bits (90), Expect = 0.055 Identities = 33/138 (23%), Positives = 65/138 (47%), Gaps = 3/138 (2%) Frame = +2 Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 406 D+R+ Q E +F + K +V HLAA G ++ + + ++ N+ ++L+ K Sbjct: 68 DVREYRQVERIFEEDKFDYVYHLAAEY-GRWNGEDYYENLWKTNVIGTKHMLRMQEKLGF 126 Query: 407 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNF---GYSYAKRMIDVLNRGYNESYGC 577 +++ S ++ D + ++ MV N P S + Y+ K +++ E +G Sbjct: 127 -RMIFFSSAEVYGDYSGLMSEDVMVKN--PISDTYQMNDYAITKWAGELMCMNSAEMFGT 183 Query: 578 MFTSVIPCNVFGPHDNFS 631 V P N +GPH+ +S Sbjct: 184 ETVRVRPVNCYGPHEKYS 201 >UniRef50_A7DQX9 Cluster: NAD-dependent epimerase/dehydratase; n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep: NAD-dependent epimerase/dehydratase - Candidatus Nitrosopumilus maritimus SCM1 Length = 308 Score = 40.3 bits (90), Expect = 0.055 Identities = 30/110 (27%), Positives = 53/110 (48%) Frame = +2 Query: 284 VIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTYP 463 VIHLAA + + ++ H + N+ + N+L+AC K NVK ++ S ++ + P Sbjct: 71 VIHLAAKID-ILQSIEHPDQTHKINVEGSLNLLRACVKNNVKNFIAASSAAVYGNPKQIP 129 Query: 464 IDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFG 613 + E + N P S Y K ++ R + +YG ++ NV+G Sbjct: 130 VTEFTIPN--PVSP---YGADKIALEFYLRAFCNAYGINGIALRFFNVYG 174 >UniRef50_Q5FRS4 Cluster: UDP-N-acetylglucosamine 4-epimerase; n=1; Gluconobacter oxydans|Rep: UDP-N-acetylglucosamine 4-epimerase - Gluconobacter oxydans (Gluconobacter suboxydans) Length = 322 Score = 39.9 bits (89), Expect = 0.073 Identities = 34/132 (25%), Positives = 57/132 (43%), Gaps = 2/132 (1%) Frame = +2 Query: 227 DLRDKTQTEALFAKHKPTH-VIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQAC-HKY 400 D+ + L A+H VIHLAA G + H+M + N+ +L+AC H Sbjct: 61 DVASPAAMQDLVARHSDLEGVIHLAAQAG-VRHSMVDPYSYVTSNVMGQVALLEACRHLK 119 Query: 401 NVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 580 + VV S+ ++ + P ET P + Y+ KR ++++ Y +G Sbjct: 120 KLTHVVYASSSSVYGRNQSVPFRETDRVERP----SSVYAVTKRAAELMSESYAYLHGIP 175 Query: 581 FTSVIPCNVFGP 616 T + V+GP Sbjct: 176 QTGLRFFTVYGP 187 >UniRef50_Q1VGF9 Cluster: Putative uncharacterized protein; n=1; Psychroflexus torquis ATCC 700755|Rep: Putative uncharacterized protein - Psychroflexus torquis ATCC 700755 Length = 268 Score = 39.9 bits (89), Expect = 0.073 Identities = 25/88 (28%), Positives = 46/88 (52%), Gaps = 4/88 (4%) Frame = +2 Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSIN----DNILQAC 391 GD+RD + + A + V+HLAA V ++ +++F +E + IN DN+L +C Sbjct: 4 GDVRDASTVHSAVAGCQA--VVHLAAQV-----SVPQSMEFPKETLEINVGGTDNLLNSC 56 Query: 392 HKYNVKKVVSCLSTCIFPDKTTYPIDET 475 + V + V S ++ +P+DE+ Sbjct: 57 NINGVSRFVLASSAAVYGTNDAFPLDES 84 >UniRef50_Q0LJ11 Cluster: NAD-dependent epimerase/dehydratase; n=4; Bacteria|Rep: NAD-dependent epimerase/dehydratase - Herpetosiphon aurantiacus ATCC 23779 Length = 317 Score = 39.9 bits (89), Expect = 0.073 Identities = 38/136 (27%), Positives = 53/136 (38%) Frame = +2 Query: 272 KPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDK 451 KP V+HLAA H + EN+ N+L+ C V + S S ++ D Sbjct: 66 KPDVVVHLAA--NAKVHELVTYPHRALENVMTTYNVLEYCRHQQVPIIFSS-SREVYGDI 122 Query: 452 TTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPHDNFS 631 Y +E S YS +K + Y Y + NV+G +DN Sbjct: 123 HRYLTEEAQADFVYTESP---YSASKISGEAFIYSYARCYNLPYLVFRFSNVYGRYDNDI 179 Query: 632 LKSSHVIPALIRRMDD 679 + VIP IRRM D Sbjct: 180 ERMERVIPLFIRRMRD 195 >UniRef50_A7GZ40 Cluster: dTDP-glucose 4,6-dehydratase; n=1; Campylobacter curvus 525.92|Rep: dTDP-glucose 4,6-dehydratase - Campylobacter curvus 525.92 Length = 345 Score = 39.9 bits (89), Expect = 0.073 Identities = 39/145 (26%), Positives = 66/145 (45%), Gaps = 10/145 (6%) Frame = +2 Query: 221 DGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRE-NMSINDNILQACHK 397 +GD+ D+ E++F K+ VIH AA N + F E N+ N+L Sbjct: 62 EGDICDRLLLESIFDKYSIKEVIHFAAETH--VDNSINKPGIFIETNVLGTFNVLDVAKS 119 Query: 398 YNVK---KVVSCLSTCIFPDKTTYPIDETMVHNG-----PPHSSNFGYSYAKRMIDVLNR 553 + ++ + TC F +T + T+ +G ++ N YS +K D++ R Sbjct: 120 FWMEGPFRYKPQYETCKFYHISTDEVYGTLGDSGYFTEKSNYAPNSPYSASKASSDMIVR 179 Query: 554 GYNESYGCMFTSVIPC-NVFGPHDN 625 YN +YG M T + C N +GP+ + Sbjct: 180 SYNRTYG-MNTLITNCSNNYGPNQH 203 >UniRef50_Q81AP5 Cluster: CDP-abequose synthase; n=2; Bacillus cereus group|Rep: CDP-abequose synthase - Bacillus cereus (strain ATCC 14579 / DSM 31) Length = 319 Score = 39.5 bits (88), Expect = 0.096 Identities = 29/87 (33%), Positives = 44/87 (50%), Gaps = 2/87 (2%) Frame = +2 Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHN--LDFFRENMSINDNILQACHKY 400 D+RDK Q + K P ++ HLAA G+ N AH + N+ NI+QA Sbjct: 60 DIRDKKQVQDAIKKINPDYIFHLAAY--GV--NSAHTDYIHAIETNVIGTCNIIQAAKLV 115 Query: 401 NVKKVVSCLSTCIFPDKTTYPIDETMV 481 N KK+++ S+ + +K PI E M+ Sbjct: 116 NCKKIINFGSSSEYGNKME-PIHENML 141 >UniRef50_Q3ESA4 Cluster: DTDP-glucose 4,6-dehydratase; n=3; Firmicutes|Rep: DTDP-glucose 4,6-dehydratase - Bacillus thuringiensis serovar israelensis ATCC 35646 Length = 320 Score = 39.5 bits (88), Expect = 0.096 Identities = 38/135 (28%), Positives = 60/135 (44%), Gaps = 4/135 (2%) Frame = +2 Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFR---ENMSIND-NILQAC 391 GD++DK LF + HLAA + N+ ++D R EN +I N+L+ C Sbjct: 56 GDIKDKKLVAQLFENNSFDLCYHLAASI-----NVQDSIDDARATFENDTIGTFNLLEQC 110 Query: 392 HKYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESY 571 Y+VK V +STC+ DK T + + P Y+ +K + + Y +Y Sbjct: 111 LNYDVKMVF--MSTCMVYDKAT---NIQGISELDPIKPASPYAGSKIAAENMVLSYYYAY 165 Query: 572 GCMFTSVIPCNVFGP 616 + P N +GP Sbjct: 166 KLPVVVIRPFNTYGP 180 >UniRef50_A6DF55 Cluster: Putative uncharacterized protein; n=1; Lentisphaera araneosa HTCC2155|Rep: Putative uncharacterized protein - Lentisphaera araneosa HTCC2155 Length = 298 Score = 39.5 bits (88), Expect = 0.096 Identities = 37/136 (27%), Positives = 61/136 (44%), Gaps = 3/136 (2%) Frame = +2 Query: 218 KDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHK 397 + GD+ DK L K+ TH++H AA+ A+ + N+ N+L+A + Sbjct: 48 EQGDILDKESILRLLQKYAVTHLLHTAAL--RTSQCKANPEQAVQVNIIGTANVLEAIRE 105 Query: 398 Y-NVKKVVSCLSTCIF--PDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNES 568 Y ++ VV + ++ P T P DE N P + N Y+ K + L Y S Sbjct: 106 YAKLEHVVFISTAAVYKVPKDGTRP-DE----NSPVEALNL-YTSTKLAGEALVESYAHS 159 Query: 569 YGCMFTSVIPCNVFGP 616 YG + + P ++GP Sbjct: 160 YGLQCSVLRPQIIYGP 175 >UniRef50_A5M424 Cluster: UDP-glucose 4-epimerase; n=1; Streptococcus pneumoniae SP11-BS70|Rep: UDP-glucose 4-epimerase - Streptococcus pneumoniae SP11-BS70 Length = 342 Score = 39.5 bits (88), Expect = 0.096 Identities = 30/107 (28%), Positives = 48/107 (44%) Frame = +2 Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 406 DL+++ + E +F +H VIH A + ++ L ++ N+ NIL+ KY V Sbjct: 61 DLKNEEKLENVFKRHNFDGVIHFAGYKA-VGESVVEPLKYYENNLLSTINILKLMKKYKV 119 Query: 407 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVL 547 V S ++ P ET P +SN Y K+ I+VL Sbjct: 120 FNFVFSSSATVYESTPIMPFYET----NPLKASN-PYGRTKQYIEVL 161 >UniRef50_Q18EM3 Cluster: Nucleoside-diphosphate-sugar epimerase; n=1; Haloquadratum walsbyi DSM 16790|Rep: Nucleoside-diphosphate-sugar epimerase - Haloquadratum walsbyi (strain DSM 16790) Length = 339 Score = 39.1 bits (87), Expect = 0.13 Identities = 41/153 (26%), Positives = 69/153 (45%), Gaps = 7/153 (4%) Frame = +2 Query: 284 VIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFP---DKT 454 V HLAA GG + + + NM++++ + +A + V+++ S C +P + Sbjct: 77 VFHLAADHGGRGYISNYPANC-ATNMALDNIVYEAAAENGVERICFASSACTYPTDIQQE 135 Query: 455 TYPIDETMV---HNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPHDN 625 + E MV G ++ Y +AK M + + YNE Y ++V +GP +N Sbjct: 136 RQRLHEEMVSFDERGGAYADEV-YGWAKLMGERSLQAYNEQYDIDTSAVRIFTAYGPREN 194 Query: 626 FSLKSSHVIPALIRRMDDAMQKGDP-TFXSDGE 721 +H A+I M AM + DP DGE Sbjct: 195 ----ETH---AIIAFMAKAMARQDPFQIWGDGE 220 >UniRef50_Q1YMT2 Cluster: UDP-glucose 4-epimerase; n=3; Alphaproteobacteria|Rep: UDP-glucose 4-epimerase - Aurantimonas sp. SI85-9A1 Length = 341 Score = 38.7 bits (86), Expect = 0.17 Identities = 20/73 (27%), Positives = 41/73 (56%) Frame = +2 Query: 218 KDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHK 397 + GD+RD + ++F++++P +IH A ++ + ++ L F+ N+S +++ A Sbjct: 55 EQGDIRDTNRLRSVFSQYQPDAIIHFAGLI-EVAQSVRDPLAFYDNNVSGTLSLITAAEA 113 Query: 398 YNVKKVVSCLSTC 436 V K+V STC Sbjct: 114 AGVDKIVFS-STC 125 >UniRef50_Q93VR3 Cluster: GDP-mannose 3,5-epimerase; n=21; cellular organisms|Rep: GDP-mannose 3,5-epimerase - Arabidopsis thaliana (Mouse-ear cress) Length = 377 Score = 38.7 bits (86), Expect = 0.17 Identities = 26/114 (22%), Positives = 47/114 (41%), Gaps = 2/114 (1%) Frame = +2 Query: 281 HVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTY 460 HV +LAA +GG+ +++ N I+ N+++A +K+ S CI+P+ Sbjct: 94 HVFNLAADMGGMGFIQSNHSVIMYNNTMISFNMIEAARINGIKRFFYASSACIYPEFKQL 153 Query: 461 PIDETMVHNGP--PHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGP 616 + P Y K + L + YN+ +G N++GP Sbjct: 154 ETTNVSLKESDAWPAEPQDAYGLEKLATEELCKHYNKDFGIECRIGRFHNIYGP 207 >UniRef50_Q42605 Cluster: UDP-glucose 4-epimerase; n=20; Viridiplantae|Rep: UDP-glucose 4-epimerase - Arabidopsis thaliana (Mouse-ear cress) Length = 351 Score = 38.7 bits (86), Expect = 0.17 Identities = 24/83 (28%), Positives = 39/83 (46%) Frame = +2 Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 403 GDLR+K E LF+K + VIH A + + ++ + +F N+ N+ + KYN Sbjct: 67 GDLRNKGDIEKLFSKQRFDAVIHFAGL-KAVGESVENPRRYFDNNLVGTINLYETMAKYN 125 Query: 404 VKKVVSCLSTCIFPDKTTYPIDE 472 K +V S ++ P E Sbjct: 126 CKMMVFSSSATVYGQPEKIPCME 148 >UniRef50_UPI0000DAE763 Cluster: hypothetical protein Rgryl_01001156; n=1; Rickettsiella grylli|Rep: hypothetical protein Rgryl_01001156 - Rickettsiella grylli Length = 341 Score = 38.3 bits (85), Expect = 0.22 Identities = 21/84 (25%), Positives = 42/84 (50%) Frame = +2 Query: 221 DGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKY 400 +GD+ D + +F ++ + VIHLA + + ++ + L + N+ ++ A K Sbjct: 58 EGDILDSNLLDHIFFENNISAVIHLAGL-KAVSESIKNPLKCYNNNVEGTLTLINAMRKS 116 Query: 401 NVKKVVSCLSTCIFPDKTTYPIDE 472 NVKK++ S ++ + PI E Sbjct: 117 NVKKLIFSSSAAVYGEPKCVPIRE 140 >UniRef50_Q9RSC3 Cluster: UDP-glucose 4-epimerase; n=1; Deinococcus radiodurans|Rep: UDP-glucose 4-epimerase - Deinococcus radiodurans Length = 394 Score = 38.3 bits (85), Expect = 0.22 Identities = 33/141 (23%), Positives = 58/141 (41%) Frame = +2 Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 403 GDL D A KP +IH AA++ + +M ++R N+ N+LQ+ + Sbjct: 50 GDLLDAASIRAALEAQKPDAIIHFAALI-EVGESMRAPGRYYRNNVVGTLNLLQSIVETR 108 Query: 404 VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 583 +V + ++ PI E P S Y KRM + + ++ ++G + Sbjct: 109 KVPLVFSSTAAVYGTTDAVPIPEDAAMQ--PESV---YGETKRMSEQMIHAFHVAHGLPY 163 Query: 584 TSVIPCNVFGPHDNFSLKSSH 646 T + NV G + +H Sbjct: 164 TVLRYFNVCGAAPGGDIGEAH 184 >UniRef50_Q65E95 Cluster: Putative uncharacterized protein; n=1; Bacillus licheniformis ATCC 14580|Rep: Putative uncharacterized protein - Bacillus licheniformis (strain DSM 13 / ATCC 14580) Length = 309 Score = 38.3 bits (85), Expect = 0.22 Identities = 29/117 (24%), Positives = 56/117 (47%) Frame = +2 Query: 275 PTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKT 454 P +++HLAA V + +++ L+ N+ + +I++A + NVKK+V S ++ + Sbjct: 68 PDYIVHLAAQVS-VAESVSDFLNDENINIRGSLHIIKAAGECNVKKIVFASSAAVYGNPD 126 Query: 455 TYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPHDN 625 P+D H P S Y K ++ + + YG + + NV+GP + Sbjct: 127 YLPVDTR--HQTNPGSP---YGLTKLTVENYLKLAYDLYGTEYCILRYSNVYGPRQD 178 >UniRef50_Q2WB63 Cluster: Nucleoside-diphosphate-sugar epimerase; n=2; Alphaproteobacteria|Rep: Nucleoside-diphosphate-sugar epimerase - Magnetospirillum magneticum (strain AMB-1 / ATCC 700264) Length = 333 Score = 38.3 bits (85), Expect = 0.22 Identities = 28/116 (24%), Positives = 52/116 (44%) Frame = +2 Query: 377 ILQACHKYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRG 556 +L+ K V + V C S+ ++ + ++E P Y AK ++ + Sbjct: 104 LLEEARKRQVSRFVYCSSSEVYGNGRDSLLNEDRTVCEPVTV----YGAAKLAGELYAKA 159 Query: 557 YNESYGCMFTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDPTFXSDGEA 724 Y+ +YG V P N +GP +++ + + VIP + R+ + + PT DG A Sbjct: 160 YHRTYGLPTVVVRPFNSYGPREHYKGQRAEVIPRFLIRVLNGL---PPTIFGDGSA 212 >UniRef50_Q8GP51 Cluster: Eps11G; n=11; Bacteria|Rep: Eps11G - Streptococcus thermophilus Length = 357 Score = 38.3 bits (85), Expect = 0.22 Identities = 30/132 (22%), Positives = 61/132 (46%), Gaps = 1/132 (0%) Frame = +2 Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQAC-HKY 400 G++ D LF K+KP+ V++LAA + +++ + + N+ NIL+AC H Sbjct: 78 GNIADTELITELFEKYKPSVVVNLAAQ-ADVRYSITNPDAYVESNLVSFFNILEACRHCE 136 Query: 401 NVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 580 +++ +V S+ ++ P + P Y+ K+ +++ Y++ Y Sbjct: 137 SLEHLVYASSSSVYGSNKKVPYSTDDKVDNPVSL----YAATKKSNELMAHAYSKLYNIP 192 Query: 581 FTSVIPCNVFGP 616 T + V+GP Sbjct: 193 STGLRFFTVYGP 204 >UniRef50_Q7D561 Cluster: NAD-dependent epimerase/dehydratase family protein; n=20; Bacteria|Rep: NAD-dependent epimerase/dehydratase family protein - Mycobacterium tuberculosis Length = 322 Score = 38.3 bits (85), Expect = 0.22 Identities = 39/170 (22%), Positives = 68/170 (40%), Gaps = 1/170 (0%) Frame = +2 Query: 254 ALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLS- 430 A+ +H+P V HLAA + + ++A N+ + +A + V+K+V S Sbjct: 72 AILEQHRPEVVFHLAAQI-DVRRSVADPQFDAAVNVIGTVRLAEAARQTGVRKIVHTSSG 130 Query: 431 TCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVF 610 I+ YP ET P Y+ K ++ + YG + + P NV+ Sbjct: 131 GSIYGTPPEYPTPET-----APTDPASPYAAGKVAGEIYLNTFRHLYGLDCSHIAPANVY 185 Query: 611 GPHDNFSLKSSHVIPALIRRMDDAMQKGDPTFXSDGEAXNHSDSLFIHXI 760 GP + H ++ A+ G PT G+ N D +F+ + Sbjct: 186 GPR-----QDPHGEAGVVAIFAQALLSGKPT-RVFGDGTNTRDYVFVDDV 229 >UniRef50_Q4HQ86 Cluster: UDP-glucose 4-epimerase, putative; n=2; Proteobacteria|Rep: UDP-glucose 4-epimerase, putative - Campylobacter upsaliensis RM3195 Length = 323 Score = 38.3 bits (85), Expect = 0.22 Identities = 35/134 (26%), Positives = 58/134 (43%) Frame = +2 Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 403 GDLRD ++L V+HL A++ + A + N+ N+L+A ++ Sbjct: 57 GDLRDSFFCDSLVKGVDA--VLHLGALIAIPYSYTAPQ-SYVDTNIQGTLNLLEASKRHG 113 Query: 404 VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 583 VK+ + ++ ++ PIDE H P S YS +K D+L Y S+ Sbjct: 114 VKRFIHTSTSEVYGSAIYTPIDEK--HPLQPQSP---YSASKIGADMLALSYFYSFNLPV 168 Query: 584 TSVIPCNVFGPHDN 625 P N +GP + Sbjct: 169 IVARPFNAYGPRQS 182 >UniRef50_Q7WNH4 Cluster: Putative NAD dependent epimerase/dehydratase; n=1; Bordetella bronchiseptica|Rep: Putative NAD dependent epimerase/dehydratase - Bordetella bronchiseptica (Alcaligenes bronchisepticus) Length = 335 Score = 37.9 bits (84), Expect = 0.29 Identities = 21/65 (32%), Positives = 32/65 (49%) Frame = +2 Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 403 GD+RD + A+FA+H T V+H AA+ GL A N+ +L A Sbjct: 55 GDVRDGARLRAVFAQHGITDVVHGAAITAGLERERAQPHAVIEVNLLGTLEVLAAAASCG 114 Query: 404 VKKVV 418 +++VV Sbjct: 115 IRRVV 119 >UniRef50_Q1FJC1 Cluster: DTDP-glucose 4,6-dehydratase; n=1; Clostridium phytofermentans ISDg|Rep: DTDP-glucose 4,6-dehydratase - Clostridium phytofermentans ISDg Length = 330 Score = 37.9 bits (84), Expect = 0.29 Identities = 30/136 (22%), Positives = 60/136 (44%), Gaps = 2/136 (1%) Frame = +2 Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 403 GD+ DK +F + V+HLAA + ++ +++FF+ N+ + Q H Sbjct: 60 GDILDKELLTTIFKEEGIDFVVHLAA-ESHVDRSLQSDIEFFQTNVIGTRMLYQVIHNVW 118 Query: 404 VKKVVSCLSTCIFPDKTTYPIDET--MVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGC 577 + + D+ ++E+ + + P H +N YS +K +++ Y ++YG Sbjct: 119 KDDISDKRILHVSTDEVYGELEESGQFIEHMPLHPNN-PYSASKAGGEMVAIAYRKTYGL 177 Query: 578 MFTSVIPCNVFGPHDN 625 N FGP+ + Sbjct: 178 PIVRTRCSNNFGPYQH 193 >UniRef50_Q11WU7 Cluster: UDP-galactose-4-epimerase; n=1; Cytophaga hutchinsonii ATCC 33406|Rep: UDP-galactose-4-epimerase - Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469) Length = 319 Score = 37.9 bits (84), Expect = 0.29 Identities = 35/156 (22%), Positives = 67/156 (42%) Frame = +2 Query: 221 DGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKY 400 +GD+R+ E + + VI A +G + ++ + N+ + N+ A + Sbjct: 57 EGDIRNY---EDVVKAVEGIEVISHQAALGSVPRSLKDPMTSNNANVLGSMNVFHAAKES 113 Query: 401 NVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 580 +VV S+ ++ D P +E + N Y+ +KR I++ + ++ Y Sbjct: 114 GADRVVYASSSSVYGDDPGSPKEEDRLGNVLSP-----YAASKRSIELYAKAFSNVYPFR 168 Query: 581 FTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQ 688 F ++ NVFGP N + VIP I + + Q Sbjct: 169 FIAMRYFNVFGPRQNAQGAYAAVIPQFITALLNGQQ 204 >UniRef50_A1GFD2 Cluster: NAD-dependent epimerase/dehydratase; n=4; Actinomycetales|Rep: NAD-dependent epimerase/dehydratase - Salinispora arenicola CNS205 Length = 332 Score = 37.9 bits (84), Expect = 0.29 Identities = 39/149 (26%), Positives = 63/149 (42%), Gaps = 1/149 (0%) Frame = +2 Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 403 GD+RD + + A V HLAA+VG + + LD N+ N L+A + Sbjct: 55 GDVRDAERL--ITAAEGVDEVYHLAAVVG-VDRYLRRPLDVVEVNVGGTHNALRAARRAG 111 Query: 404 VKKVVSCLSTCIFPD-KTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 580 + VVS S + + + D+ V G + + YS +K + L Y+ G Sbjct: 112 ARIVVSSTSEVYGRNPRVPWREDDDRVL-GSTATDRWSYSTSKAAAEHLAFAYHRQEGLP 170 Query: 581 FTSVIPCNVFGPHDNFSLKSSHVIPALIR 667 T + NV+GP + S I ++R Sbjct: 171 VTVLRYFNVYGPRQRPAYVLSRSIVRMLR 199 >UniRef50_Q5UXR0 Cluster: UDP-glucose 4-epimerase; n=3; Halobacteriaceae|Rep: UDP-glucose 4-epimerase - Haloarcula marismortui (Halobacterium marismortui) Length = 310 Score = 37.9 bits (84), Expect = 0.29 Identities = 40/145 (27%), Positives = 63/145 (43%), Gaps = 2/145 (1%) Frame = +2 Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 403 GD+R+ E+ A VIHLAA+ G + + + F N +N+L A K Sbjct: 56 GDIREYGDVES--AMRGVDRVIHLAAITGASSTHERRD-ETFAINYDGTENVLTAAGKLG 112 Query: 404 VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 583 V VV S ++ T+ IDET+ P N Y+ K + L + Y E + Sbjct: 113 VDHVVFASSCNVYGRATSTDIDETV----DPDPIN-PYAETKLQSETLLQEYCEEFDMTG 167 Query: 584 TSVIPCNVFG--PHDNFSLKSSHVI 652 T++ FG P F+L ++ + Sbjct: 168 TALRMATNFGHSPGIRFNLVVNYFV 192 >UniRef50_A6GG02 Cluster: Putative uncharacterized protein; n=1; Plesiocystis pacifica SIR-1|Rep: Putative uncharacterized protein - Plesiocystis pacifica SIR-1 Length = 313 Score = 37.5 bits (83), Expect = 0.39 Identities = 37/147 (25%), Positives = 62/147 (42%) Frame = +2 Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 403 GD+R+ E A VIHLAA G + ++ R N+ N+L AC + Sbjct: 53 GDIRELACCE--HAVRDVDAVIHLAAR-GSVPRSIDDPQATMRTNVMGTTNVLDACRRAG 109 Query: 404 VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 583 V++VV S+ I+ P E P S Y+ +K + + + ++ +G Sbjct: 110 VRRVVQSSSSSIYGVVPGLPRREQ--QRPDPRSP---YAASKLAAEHVAQAWHACWGVEV 164 Query: 584 TSVIPCNVFGPHDNFSLKSSHVIPALI 664 ++ NV+GP + V+P I Sbjct: 165 VTLRLFNVYGPRQRSDSSYAAVVPLFI 191 >UniRef50_Q8WUS8 Cluster: HSPC105 protein; n=21; Euteleostomi|Rep: HSPC105 protein - Homo sapiens (Human) Length = 383 Score = 37.5 bits (83), Expect = 0.39 Identities = 34/138 (24%), Positives = 60/138 (43%), Gaps = 7/138 (5%) Frame = +2 Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRE-NMSINDNILQACHKY 400 GD+R + E F T V H+A+ G+ N + +E N+ DNILQ C + Sbjct: 56 GDIRHLSDVEKAFQDADVTCVFHIASY--GMSGREQLNRNLIKEVNVRGTDNILQVCQRR 113 Query: 401 NVKKVV-SCLSTCIFPDKTTYPIDETM----VHNGPPHSSNFGYSYAKRMIDVLNRGYNE 565 V ++V + IF + DE++ +H P H S +++++ + Sbjct: 114 RVPRLVYTSTFNVIFGGQVIRNGDESLPYLPLHLHPDHYSRTKSIAEQKVLEANATPLDR 173 Query: 566 SYGCMFTSVI-PCNVFGP 616 G + T + P ++GP Sbjct: 174 GDGVLRTCALRPAGIYGP 191 >UniRef50_Q2FS05 Cluster: NAD-dependent epimerase/dehydratase; n=2; cellular organisms|Rep: NAD-dependent epimerase/dehydratase - Methanospirillum hungatei (strain JF-1 / DSM 864) Length = 343 Score = 37.5 bits (83), Expect = 0.39 Identities = 40/168 (23%), Positives = 68/168 (40%), Gaps = 2/168 (1%) Frame = +2 Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVG-GLFHNMAHNLDFFRENMSINDNILQACHKY 400 G + D LF K+K +V HL A GL H + + N+ + N++ K Sbjct: 58 GSVSDANLITELFTKYKFEYVYHLGAYAAEGLSHFIRR--FNYTNNLIGSINLINEAVKV 115 Query: 401 NVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 580 K V S ++ I+ M PH + Y +K +++ + +G Sbjct: 116 GTKCFVFTSSIAVYG-----AIEPPMTEEKTPHPED-PYGISKLAVELDLMAAHSMFGLN 169 Query: 581 FTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDP-TFXSDGE 721 + P NV+G + N S +VI ++++ + G P T DGE Sbjct: 170 YVIFRPHNVYGEYQNLSDPYRNVIGIFMKQIFE----GQPMTIFGDGE 213 >UniRef50_Q982P5 Cluster: UDP-glucose 4-epimerase; n=1; Mesorhizobium loti|Rep: UDP-glucose 4-epimerase - Rhizobium loti (Mesorhizobium loti) Length = 310 Score = 37.1 bits (82), Expect = 0.51 Identities = 36/134 (26%), Positives = 59/134 (44%), Gaps = 2/134 (1%) Frame = +2 Query: 221 DGDLRDKTQ-TEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHK 397 +GD RD T+AL + H++H + +MA ++ R+++ + +L AC + Sbjct: 49 EGDFRDNLAVTKALQSHDTVIHLVH-STWPSTADADMAADI---RDSVIPSVELLDACVR 104 Query: 398 YNVKKVVSCLSTCIFPDKTTY-PIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYG 574 VK+++ S T Y +DE + P + Y +K MI+ R Y YG Sbjct: 105 SGVKRIIYFSS-----GGTVYGEVDEIPIREDSPTNPVGAYGVSKLMIEHYVRLYERKYG 159 Query: 575 CMFTSVIPCNVFGP 616 V N FGP Sbjct: 160 LNSFIVRLANPFGP 173 >UniRef50_Q8ECF4 Cluster: DTDP-glucose 4,6-dehydratase; n=18; Gammaproteobacteria|Rep: DTDP-glucose 4,6-dehydratase - Shewanella oneidensis Length = 375 Score = 37.1 bits (82), Expect = 0.51 Identities = 35/148 (23%), Positives = 60/148 (40%), Gaps = 1/148 (0%) Frame = +2 Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 406 D+ D+T+ E +F+ H+P V+HLAA + ++ + DF + N+ +L+A Y + Sbjct: 58 DICDRTELERVFSLHQPDAVMHLAA-ESHVDRSITGSADFIQTNIVGTYTLLEAARHYWM 116 Query: 407 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAK-RMIDVLNRGYNESYGCMF 583 + S F +T + + H P N S D S +F Sbjct: 117 QLNTERKSAFRFHHISTDEVYGDLPH---PDEINVECSMLNDECKDHSTLNIQHSTLPLF 173 Query: 584 TSVIPCNVFGPHDNFSLKSSHVIPALIR 667 T P P+ S H++ A +R Sbjct: 174 TETTPYTPSSPYSASKASSDHLVRAWLR 201 >UniRef50_Q1QD53 Cluster: NAD-dependent epimerase/dehydratase; n=3; Bacteria|Rep: NAD-dependent epimerase/dehydratase - Psychrobacter cryohalolentis (strain K5) Length = 333 Score = 37.1 bits (82), Expect = 0.51 Identities = 28/124 (22%), Positives = 54/124 (43%), Gaps = 2/124 (1%) Frame = +2 Query: 251 EALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN-VKKVVSCL 427 E + K + + AA + G+ + + + NM N L+A H+ V++ + Sbjct: 65 EKIIEAAKGSEIFIHAAAIAGIDNTVKSPVRTMTVNMIGTANALEAAHQAGTVQRFLEFS 124 Query: 428 STCIFPDKTTYPIDE-TMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCN 604 ++ +F + Y +DE G + + Y+ +K + L YN +G + P N Sbjct: 125 TSEVFGSRA-YRVDELNSTTTGAVGEARWTYAVSKLAGEHLTHAYNREHGLPTVTFRPFN 183 Query: 605 VFGP 616 V+GP Sbjct: 184 VYGP 187 >UniRef50_Q0BRM8 Cluster: UDP-glucose 4-epimerase; n=2; Rhodospirillales|Rep: UDP-glucose 4-epimerase - Granulobacter bethesdensis (strain ATCC BAA-1260 / CGDNIH1) Length = 342 Score = 37.1 bits (82), Expect = 0.51 Identities = 33/150 (22%), Positives = 66/150 (44%), Gaps = 4/150 (2%) Frame = +2 Query: 227 DLRDKTQTEALFAKHKPTHVIHLAA--MVGGLFHNMAHNLDFFRENMSINDNILQACHKY 400 DL D+T A A+ + V+H AA +VG +M + + +N ++ ++ AC ++ Sbjct: 65 DLADETTLHATLAEGQWDGVMHFAARSLVG---ESMVDPMLYMNQNAALGFKLIAACVQH 121 Query: 401 NVKKVVSCLSTCIFPDKTTYPIDE-TMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGC 577 V + + + +F PIDE + G P+ + +R + +R + Y C Sbjct: 122 KVPRFLLSSTAALFGHHDDTPIDENAAIQPGSPYGES--KLMIERALSWADRIHGLRYAC 179 Query: 578 M-FTSVIPCNVFGPHDNFSLKSSHVIPALI 664 + + + + G +H+IP +I Sbjct: 180 LRYFNAAGADPQGRSGEDHDPETHLIPLVI 209 >UniRef50_A6GE58 Cluster: NAD-dependent epimerase/dehydratase family protein; n=1; Plesiocystis pacifica SIR-1|Rep: NAD-dependent epimerase/dehydratase family protein - Plesiocystis pacifica SIR-1 Length = 360 Score = 37.1 bits (82), Expect = 0.51 Identities = 42/168 (25%), Positives = 71/168 (42%), Gaps = 4/168 (2%) Frame = +2 Query: 227 DLRDKTQTEALFAKHKPT-HVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 403 D+RD A+ HV+H AA V + +A N+ N+L+A Sbjct: 81 DVRDPEALRQACARFDGVEHVLHHAA-VASVPRTLAEPETAHSVNVDGMFNLLEAARACG 139 Query: 404 VKKVVSCLSTCIFPDKTTYPID--ETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGC 577 K VV S+ ++ D P ++ G P S Y+ KR+ +VL + ++ ++G Sbjct: 140 AKSVVHATSSAVYGDCPGAPETGAQSEAIIGRPLSP---YAGQKRIAEVLGQTWSTTHGM 196 Query: 578 MFTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGD-PTFXSDG 718 + N+ GP + + + VIP I D + +G+ P DG Sbjct: 197 SVVGLRYFNIVGPRQDPNGAYAAVIPKWI----DTLARGEQPVIFGDG 240 >UniRef50_A4QBQ0 Cluster: Putative uncharacterized protein; n=1; Corynebacterium glutamicum R|Rep: Putative uncharacterized protein - Corynebacterium glutamicum (strain R) Length = 335 Score = 37.1 bits (82), Expect = 0.51 Identities = 20/83 (24%), Positives = 41/83 (49%) Frame = +2 Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 403 GD+RD+ +++ A+++P+ IH AA + ++ + N+ +L A H Sbjct: 62 GDIRDRAFVDSVLAQYQPSAAIHFAAK-KAVGESVEQPTMYLNINIGGTATLLDALHHAG 120 Query: 404 VKKVVSCLSTCIFPDKTTYPIDE 472 V+ +V S + + T P++E Sbjct: 121 VRDIVFSSSCSVHGETTHSPLNE 143 >UniRef50_Q57664 Cluster: Putative UDP-glucose 4-epimerase; n=3; cellular organisms|Rep: Putative UDP-glucose 4-epimerase - Methanococcus jannaschii Length = 305 Score = 37.1 bits (82), Expect = 0.51 Identities = 44/168 (26%), Positives = 71/168 (42%), Gaps = 2/168 (1%) Frame = +2 Query: 221 DGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRE-NMSINDNILQACHK 397 + D+RDK E + K VIH AA + N N + + N+ NIL+ K Sbjct: 48 NADIRDKDLDEKINFKDVEV-VIHQAAQIN--VRNSVENPVYDGDINVLGTINILEMMRK 104 Query: 398 YNVKKVVSCLS-TCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYG 574 Y++ K+V S ++ + P+DE H P S Y +K + + + YN YG Sbjct: 105 YDIDKIVFASSGGAVYGEPNYLPVDEN--HPINPLSP---YGLSKYVGEEYIKLYNRLYG 159 Query: 575 CMFTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDPTFXSDG 718 + + NV+G + + VI I +M ++ P DG Sbjct: 160 IEYAILRYSNVYGERQD-PKGEAGVISIFIDKM---LKNQSPIIFGDG 203 >UniRef50_Q7UXZ2 Cluster: 3-beta-hydroxysteroid dehydrogenase; n=2; Planctomycetaceae|Rep: 3-beta-hydroxysteroid dehydrogenase - Rhodopirellula baltica Length = 339 Score = 36.7 bits (81), Expect = 0.68 Identities = 33/130 (25%), Positives = 60/130 (46%), Gaps = 1/130 (0%) Frame = +2 Query: 284 VIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCI-FPDKTTY 460 VIH AA V G++ + H +F N+ + N+LQAC + V +++ S + F Sbjct: 67 VIHTAA-VAGVWGSWQH---YFDNNVVASRNVLQACQELGVSQLIYTSSPSVTFDGNDQR 122 Query: 461 PIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPHDNFSLKS 640 +DE + P + Y + K + + ++ G S+ P ++GP D Sbjct: 123 DVDEAEPY---PETWMCHYPHTKSIAEREILAADQPGGMRTVSLRPHLIWGPDD------ 173 Query: 641 SHVIPALIRR 670 H+IP +++R Sbjct: 174 PHLIPRVLQR 183 >UniRef50_A6Q4T4 Cluster: NAD-dependent epimerase/dehydratase; n=1; Nitratiruptor sp. SB155-2|Rep: NAD-dependent epimerase/dehydratase - Nitratiruptor sp. (strain SB155-2) Length = 294 Score = 36.7 bits (81), Expect = 0.68 Identities = 38/162 (23%), Positives = 69/162 (42%), Gaps = 5/162 (3%) Frame = +2 Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQAC--HKY 400 D+ K Q +F K ++IHLAA+ F A + + N N+L A ++ Sbjct: 44 DITKKEQIRQIFQKKSFDYIIHLAAI---SFVGYADQVKMYEVNAFGVQNLLSALEEQEW 100 Query: 401 NVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 580 KKV+ S ++ + T + E + N H Y+Y+K + + + + Y + + Sbjct: 101 TAKKVIITSSATVYGMQRTNKLHEKLCPNPNNH-----YAYSKYISEQIAKTYFDKIPII 155 Query: 581 FTSVIPCNVFGPHDNFSLKSSHVIPALIR---RMDDAMQKGD 697 T P N G + ++P L+R R D ++ G+ Sbjct: 156 ITR--PFNYTG----CGQREEFIVPKLVRAFQRKDSIIEIGN 191 >UniRef50_A3ERM8 Cluster: UDP-glucose 4-epimerase; n=1; Leptospirillum sp. Group II UBA|Rep: UDP-glucose 4-epimerase - Leptospirillum sp. Group II UBA Length = 323 Score = 36.7 bits (81), Expect = 0.68 Identities = 31/150 (20%), Positives = 69/150 (46%), Gaps = 3/150 (2%) Frame = +2 Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 403 GD+RD +LF+ + VIH AA + + ++ L ++ N++ IL+ + Sbjct: 50 GDIRDPRALTSLFSHYPIEAVIHFAAAI-EVGESVQDPLKYWDNNLNGTLRILETMRSFG 108 Query: 404 VKKVVSCLSTCIFPDKTTYPI-DETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 580 V+ ++ + ++ K+ PI +E + P+ + A+R+++ + S Sbjct: 109 VRNLILSSTAAVYSPKSDGPITEEDRIDPQNPYGET--KAAAERLVEACRHAFGVSSVIF 166 Query: 581 --FTSVIPCNVFGPHDNFSLKSSHVIPALI 664 F + +G + ++ SH+IPA++ Sbjct: 167 RYFNAAALEPSYGLVSH-AIPRSHLIPAVL 195 >UniRef50_A6SIX9 Cluster: Putative uncharacterized protein; n=1; Botryotinia fuckeliana B05.10|Rep: Putative uncharacterized protein - Botryotinia fuckeliana B05.10 Length = 348 Score = 36.7 bits (81), Expect = 0.68 Identities = 25/79 (31%), Positives = 36/79 (45%) Frame = +2 Query: 221 DGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKY 400 DGD+ ++F KP VIH A+ V N F++ N+ +++AC K Sbjct: 58 DGDITSLESLLSIFNSIKPDVVIHTASPVA----ITGTNDLFYKVNVGGTKCVVEACQKT 113 Query: 401 NVKKVVSCLSTCIFPDKTT 457 VK +V S I D TT Sbjct: 114 GVKALVFTSSASIISDNTT 132 >UniRef50_Q5V6W4 Cluster: UDP-glucose 4-epimerase; n=1; Haloarcula marismortui|Rep: UDP-glucose 4-epimerase - Haloarcula marismortui (Halobacterium marismortui) Length = 309 Score = 36.7 bits (81), Expect = 0.68 Identities = 44/167 (26%), Positives = 68/167 (40%), Gaps = 1/167 (0%) Frame = +2 Query: 221 DGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKY 400 +GD+RD+ +A A V H AAMV + ++ +D N + N+ C + Sbjct: 56 EGDVRDRETLDA--AIEGVDVVFHEAAMVS-VPESIEQPVDCHELNGTATVNVFD-CARR 111 Query: 401 NVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 580 +VV S ++ PI E P N Y + K + + R Y E YG Sbjct: 112 QDTRVVFASSAAVYGVPDDVPIGEDA-----PTEPNSPYGFEKYLGEQYARFYTEEYGLP 166 Query: 581 FTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDP-TFXSDG 718 + NV+GP + + VI +R+ Q G+P T DG Sbjct: 167 TVPLRYFNVYGPR-GLDGEYAGVIGTFVRQ----AQAGEPLTVEGDG 208 >UniRef50_Q65D61 Cluster: Putative uncharacterized protein; n=1; Bacillus licheniformis ATCC 14580|Rep: Putative uncharacterized protein - Bacillus licheniformis (strain DSM 13 / ATCC 14580) Length = 331 Score = 36.3 bits (80), Expect = 0.90 Identities = 28/132 (21%), Positives = 55/132 (41%) Frame = +2 Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 403 GD+RD+ + +F V+H AA + + F EN++ + +L +Y+ Sbjct: 50 GDIRDRHFLKQVFENEDIEAVMHFAA--SPISSKSKNVFTSFNENITGMETLLDVMKEYD 107 Query: 404 VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 583 V ++V S ++ P+ E P H+ + K M++ + ++YG + Sbjct: 108 VGRIVFASSAAVYGSPEDLPVTEE-TEPEPVHA----HGKVKWMMEKMLMEAEKAYGLKY 162 Query: 584 TSVIPCNVFGPH 619 + N G H Sbjct: 163 VILRSFNACGAH 174 >UniRef50_A3Q712 Cluster: UDP-glucose 4-epimerase; n=6; Actinobacteria (class)|Rep: UDP-glucose 4-epimerase - Mycobacterium sp. (strain JLS) Length = 329 Score = 36.3 bits (80), Expect = 0.90 Identities = 35/131 (26%), Positives = 53/131 (40%), Gaps = 1/131 (0%) Frame = +2 Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAM-VGGLFHNMAHNLDFFRENMSINDNILQACHKY 400 G L D E +H+ T VIH+A G+ ++ L + +N+S +LQA Sbjct: 50 GTLLDGALVEQALREHEVTGVIHIAGFKYAGV--SVQRPLHTYEQNVSAMVTLLQAMETV 107 Query: 401 NVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 580 V K+V S F +DE+ P + Y K + + L R + G Sbjct: 108 GVDKIVFSSSAATFGTPDVDQVDES-----TPTAPESPYGETKLIGEWLLRDAGRASGLR 162 Query: 581 FTSVIPCNVFG 613 TS+ NV G Sbjct: 163 HTSLRYFNVVG 173 >UniRef50_Q2FKD1 Cluster: NAD-dependent epimerase/dehydratase family protein; n=13; Staphylococcus aureus|Rep: NAD-dependent epimerase/dehydratase family protein - Staphylococcus aureus (strain USA300) Length = 326 Score = 35.9 bits (79), Expect = 1.2 Identities = 43/168 (25%), Positives = 75/168 (44%), Gaps = 4/168 (2%) Frame = +2 Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN- 403 D+R+ E + ++ +VIHLAA+V + ++ + N+ +L+ KYN Sbjct: 56 DIREYDAVEQIMKTYQFDYVIHLAALV-SVAESVEKPILSQEINVVATLRLLEIIKKYNN 114 Query: 404 -VKKVVSCLSTCIFPDKTTYP-IDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGC 577 +K+ + S ++ D P D++++ P++ Y +R LN Y Y Sbjct: 115 HIKRFIFASSAAVYGDLPDLPKSDQSLILPLSPYA--IDKYYGER--TTLN--YCSLYNI 168 Query: 578 MFTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDP-TFXSDG 718 V NVFGP + KS + +I +M D+ + P TF DG Sbjct: 169 PTAVVKFFNVFGPRQD--PKSQY--SGVISKMFDSFEHNKPFTFFGDG 212 >UniRef50_Q1GKR7 Cluster: UDP-glucose 4-epimerase; n=17; Bacteria|Rep: UDP-glucose 4-epimerase - Silicibacter sp. (strain TM1040) Length = 327 Score = 35.9 bits (79), Expect = 1.2 Identities = 33/160 (20%), Positives = 66/160 (41%), Gaps = 6/160 (3%) Frame = +2 Query: 206 FSGSKDGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQ 385 F + GDL D+ + + +FA++KP V+H AA+ + M+ ++ N+ + +++ Sbjct: 44 FGPFEQGDLTDRGRLDEVFAQYKPVAVMHFAAL-SQVGEAMSEPGRYWANNVGGSLCLIE 102 Query: 386 ACHKYNVKKVVSCLSTCIFPDKTTY-PIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYN 562 A CL TY D ++ P Y +KR ++ + + + Sbjct: 103 AA------VAAGCLDFVFSSTCATYGEHDNVVLDENTPQQPLNAYGASKRAVEDILKDFE 156 Query: 563 ESYGCMFTSVIPCNVFGPH-----DNFSLKSSHVIPALIR 667 ++G NV G F +H++P +I+ Sbjct: 157 AAHGLRSVIFRYFNVAGADPEAEVGEFHQPETHLVPLMIQ 196 >UniRef50_P14169 Cluster: CDP-paratose 2-epimerase; n=12; cellular organisms|Rep: CDP-paratose 2-epimerase - Salmonella typhi Length = 338 Score = 35.9 bits (79), Expect = 1.2 Identities = 28/110 (25%), Positives = 49/110 (44%), Gaps = 5/110 (4%) Frame = +2 Query: 161 DRQKRNSDYDSETWIFS-GSKD---GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNM 328 D R D+ W+ S G+ + GD+R+K L K+ P HLA V + ++ Sbjct: 31 DNLSRKGATDNLHWLSSLGNFEFVHGDIRNKNDVTRLITKYMPDSCFHLAGQV-AMTTSI 89 Query: 329 AHNLDFFRENMSINDNILQACHKYNVK-KVVSCLSTCIFPDKTTYPIDET 475 + F N+ N+L+A +YN ++ + ++ D Y +ET Sbjct: 90 DNPCMDFEINVGGTLNLLEAVRQYNSNCNIIYSSTNKVYGDLEQYKYNET 139 >UniRef50_UPI0001597850 Cluster: hypothetical protein RBAM_031220; n=1; Bacillus amyloliquefaciens FZB42|Rep: hypothetical protein RBAM_031220 - Bacillus amyloliquefaciens FZB42 Length = 309 Score = 35.5 bits (78), Expect = 1.6 Identities = 19/64 (29%), Positives = 32/64 (50%) Frame = +2 Query: 284 VIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTYP 463 V+HLAAMV G+ ++ D R N N+ + C + + ++ S+ +F D +P Sbjct: 63 VVHLAAMV-GVDSCRSNEEDVIRVNFEGTKNVTEVCGELGISTLLFSSSSEVFGDSPDFP 121 Query: 464 IDET 475 ET Sbjct: 122 YTET 125 >UniRef50_Q97KX2 Cluster: Nucleoside-diphosphate-sugar epimerase; n=2; Clostridium|Rep: Nucleoside-diphosphate-sugar epimerase - Clostridium acetobutylicum Length = 315 Score = 35.5 bits (78), Expect = 1.6 Identities = 32/118 (27%), Positives = 53/118 (44%), Gaps = 1/118 (0%) Frame = +2 Query: 269 HKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPD 448 +K ++IHLAA+VG M ++ + + + DN+L+A H YN K + S+ I+ Sbjct: 64 NKCDYIIHLAAVVGVRLA-MLKGIEGLKVSCTGTDNMLEAAHLYN-KGIFISSSSAIYGK 121 Query: 449 KTTYPIDETMVH-NGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPH 619 + +DE G ++ YS K + L Y+ G NV GP+ Sbjct: 122 ISKKSVDEEDDSVLGTSKKPSWLYSVGKLTEEHLVLAYHRELGVKVKIGRFFNVIGPY 179 >UniRef50_Q8RGC6 Cluster: UDP-glucose 4-epimerase; n=2; Fusobacterium nucleatum|Rep: UDP-glucose 4-epimerase - Fusobacterium nucleatum subsp. nucleatum Length = 324 Score = 35.5 bits (78), Expect = 1.6 Identities = 29/138 (21%), Positives = 65/138 (47%), Gaps = 1/138 (0%) Frame = +2 Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 403 G+++D +F ++K V+H A + + ++ ++ N ++Q+ K+N Sbjct: 51 GNVQDYELMSRIFQENKIEAVMHFAGYIR-VPESVDDPNKYYLNNTYTTMCLIQSMVKHN 109 Query: 404 VKKVVSCLSTCIFPDKTT-YPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 580 +K ++ + ++ + T PIDE H+ P + Y +K M + + R ++YG Sbjct: 110 IKNIIFSSTAAVYGEITEDNPIDEK--HSTIPINP---YGASKLMSERIIRDCAKAYGLN 164 Query: 581 FTSVIPCNVFGPHDNFSL 634 ++ NV G H+ + + Sbjct: 165 YSIFRYFNVAGAHEKYPI 182 >UniRef50_A7DIX5 Cluster: NAD-dependent epimerase/dehydratase; n=2; Methylobacterium extorquens PA1|Rep: NAD-dependent epimerase/dehydratase - Methylobacterium extorquens PA1 Length = 323 Score = 35.5 bits (78), Expect = 1.6 Identities = 31/116 (26%), Positives = 49/116 (42%), Gaps = 2/116 (1%) Frame = +2 Query: 377 ILQACHKYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSY--AKRMIDVLN 550 + +AC + V +V S ++ P DET + P S N YSY +K + +++ Sbjct: 102 VSEACIEAGVPDLVVASSAEVYQTPRVVPTDET-IEMVIPDSLNPRYSYGGSKLISELIA 160 Query: 551 RGYNESYGCMFTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDPTFXSDG 718 Y P N++GP + HV+P LI ++ A G T DG Sbjct: 161 FNYCRDKLRKVQVFRPHNIYGPDMGWK----HVVPQLIEKIVAAGDGGSITLQGDG 212 >UniRef50_A6PTX1 Cluster: NAD-dependent epimerase/dehydratase; n=1; Victivallis vadensis ATCC BAA-548|Rep: NAD-dependent epimerase/dehydratase - Victivallis vadensis ATCC BAA-548 Length = 305 Score = 35.5 bits (78), Expect = 1.6 Identities = 45/186 (24%), Positives = 75/186 (40%) Frame = +2 Query: 221 DGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKY 400 +GD+RD+ A +V HLAAM+ + +M ++ N + +L+ K Sbjct: 49 EGDIRDRITVAK--AMEDVDYVFHLAAMIS-VPESMTKIIECIDINNTGMLIVLEEAAKA 105 Query: 401 NVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 580 VKK+ S I+ D P ETM P S Y+ K + + +N++ Sbjct: 106 GVKKLCFSTSAAIYGDNPVVPKVETMFPE--PKSP---YAITKLDGEYYCKMFNDTGKLK 160 Query: 581 FTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDPTFXSDGEAXNHSDSLFIHXI 760 + NVFGP + + +P + A+ T DGE D +++ I Sbjct: 161 TACLRYFNVFGPRQDPKSAYAAAVPIFTAK---AVANEPLTIFGDGEQTR--DFIYVKDI 215 Query: 761 SASCSF 778 A+ F Sbjct: 216 VAANVF 221 >UniRef50_A6BZU3 Cluster: Putative uncharacterized protein; n=1; Planctomyces maris DSM 8797|Rep: Putative uncharacterized protein - Planctomyces maris DSM 8797 Length = 324 Score = 35.5 bits (78), Expect = 1.6 Identities = 37/144 (25%), Positives = 61/144 (42%) Frame = +2 Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 403 GDLRD E A + V H AA+ + ++ H LD ++ ++L A + Sbjct: 54 GDLRDLAAVEQATAGVEI--VFHQAALAS-VPRSVEHPLDTHEACVTGTVHVLDAARRSG 110 Query: 404 VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 583 V++VV S+ + ++ P H G Y+ AK ++ + + SY Sbjct: 111 VQRVVYAGSSSAYGNQEQMP-----KHEGQTPEVLSPYAAAKLAGELYCQAFANSYDLET 165 Query: 584 TSVIPCNVFGPHDNFSLKSSHVIP 655 + NVFGP + + S VIP Sbjct: 166 VRIRYFNVFGPRQDPNSPYSAVIP 189 >UniRef50_A3H6D1 Cluster: NAD-dependent epimerase/dehydratase; n=1; Caldivirga maquilingensis IC-167|Rep: NAD-dependent epimerase/dehydratase - Caldivirga maquilingensis IC-167 Length = 326 Score = 35.5 bits (78), Expect = 1.6 Identities = 26/118 (22%), Positives = 52/118 (44%) Frame = +2 Query: 221 DGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKY 400 + DL D + ++ + +IHLAAM+ L + L + N+ N+ +A Sbjct: 52 NADLSDFDELISIIKRFNVRRIIHLAAMI--LLESRNRPLKAAKVNIIGTLNVFEAARLM 109 Query: 401 NVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYG 574 ++++VV S ++ Y ++ + PH+ Y K ++ Y+E+YG Sbjct: 110 DLERVVYASSESVYGSPLVYG-KGSVNEDDYPHTPPDPYHITKLADELFGSYYSEAYG 166 >UniRef50_Q8KNN2 Cluster: DTDP-D-glucose-4,6-dehydratase; n=4; Bacteria|Rep: DTDP-D-glucose-4,6-dehydratase - Aeromonas hydrophila Length = 379 Score = 35.1 bits (77), Expect = 2.1 Identities = 37/146 (25%), Positives = 66/146 (45%), Gaps = 15/146 (10%) Frame = +2 Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKY-- 400 D+ ++ + + +FA+H+P V+HLAA + ++ DF N+ +L+A Y Sbjct: 76 DICNRAELDRVFAQHQPDAVMHLAA-ESHVDRSITGPADFIETNIVGTYMLLEAARAYWN 134 Query: 401 ---NVKKVV---SCLST------CIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDV 544 V+K +ST PD+ + + P++ + YS +K D Sbjct: 135 GLDEVRKAAFRFHHISTDEVYGDLPHPDEVAPGVALPLFTETTPYAPSSPYSASKASSDH 194 Query: 545 LNRGYNESYGCMFTSVIPC-NVFGPH 619 L R + +YG + T V C N +GP+ Sbjct: 195 LVRAWRRTYG-LPTIVTNCSNNYGPY 219 >UniRef50_A7HN54 Cluster: Polysaccharide biosynthesis protein CapD; n=2; Thermotogaceae|Rep: Polysaccharide biosynthesis protein CapD - Fervidobacterium nodosum Rt17-B1 Length = 606 Score = 35.1 bits (77), Expect = 2.1 Identities = 28/80 (35%), Positives = 39/80 (48%), Gaps = 1/80 (1%) Frame = +2 Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNL-DFFRENMSINDNILQACHKYN 403 D+ DK E +F H+P V H AA F M +NL + R N+ N+ + YN Sbjct: 341 DVTDKNMMEKIFKTHRPDIVFHAAAHKHVFF--MQNNLYEALRVNVLGTINLAKLSCNYN 398 Query: 404 VKKVVSCLSTCIFPDKTTYP 463 V+K V +ST DK +P Sbjct: 399 VEKFV-FIST----DKAVHP 413 >UniRef50_A6CEQ2 Cluster: Putative uncharacterized protein; n=1; Planctomyces maris DSM 8797|Rep: Putative uncharacterized protein - Planctomyces maris DSM 8797 Length = 333 Score = 34.7 bits (76), Expect = 2.7 Identities = 40/151 (26%), Positives = 66/151 (43%), Gaps = 2/151 (1%) Frame = +2 Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 403 GD+RD T E A V H AA V G++ + + F+ N N++ +C Sbjct: 48 GDIRDATTVER--ACEGIETVYHTAA-VSGIWGHWDY---FYSINTRGTLNVIASCQSQG 101 Query: 404 VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNF--GYSYAKRMIDVLNRGYNESYGC 577 V ++V S + D + + E + P+S +F Y + K + + N G Sbjct: 102 VTRLVYTSSPSVVYDGSAH---ENATES-LPYSEHFLCHYPHTKMLAERAVLQANGENGL 157 Query: 578 MFTSVIPCNVFGPHDNFSLKSSHVIPALIRR 670 ++ P ++GP DN H+IP LI+R Sbjct: 158 ATVALRPHLIWGPRDN------HLIPRLIQR 182 >UniRef50_A0LGE9 Cluster: NAD-dependent epimerase/dehydratase; n=1; Syntrophobacter fumaroxidans MPOB|Rep: NAD-dependent epimerase/dehydratase - Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB) Length = 315 Score = 34.7 bits (76), Expect = 2.7 Identities = 23/85 (27%), Positives = 38/85 (44%) Frame = +2 Query: 515 YSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKG 694 Y AK M++ ++ YG + V P N FGP N+ + VIP R++ D Sbjct: 144 YGVAKLMMEKYLYMFSYLYGLEYIIVRPSNPFGPRQNY-MGEQGVIPIFFRKILD----- 197 Query: 695 DPTFXSDGEAXNHSDSLFIHXISAS 769 D T G+ D L++ ++ + Sbjct: 198 DETISIWGDGKGTKDYLYVEDLAGA 222 >UniRef50_Q8ZW82 Cluster: UDP-glucose 4-epimerase; n=6; Thermoprotei|Rep: UDP-glucose 4-epimerase - Pyrobaculum aerophilum Length = 314 Score = 34.7 bits (76), Expect = 2.7 Identities = 23/90 (25%), Positives = 37/90 (41%) Frame = +2 Query: 347 FRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYA 526 F EN+ N+L+ + VK V+ S+ ++ D P E P+ Y A Sbjct: 86 FNENVLATFNVLEWARQTGVKSVIFASSSTVYGDAEVIPTPEE-----APYKPISVYGAA 140 Query: 527 KRMIDVLNRGYNESYGCMFTSVIPCNVFGP 616 K +V+ Y YG ++ N+ GP Sbjct: 141 KAAGEVMCATYARLYGVKCLAIRYANIIGP 170 >UniRef50_P18645 Cluster: UDP-glucose 4-epimerase; n=353; cellular organisms|Rep: UDP-glucose 4-epimerase - Rattus norvegicus (Rat) Length = 347 Score = 34.7 bits (76), Expect = 2.7 Identities = 24/91 (26%), Positives = 42/91 (46%) Frame = +2 Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 406 D+ D+ + LF KH VIH A + + ++ LD++R N++ +L+ V Sbjct: 66 DILDQAALQHLFKKHNFKAVIHFAGL-KAVGESVQKPLDYYRVNLTGTIQLLEIMRAMGV 124 Query: 407 KKVVSCLSTCIFPDKTTYPIDETMVHNGPPH 499 K +V S ++ P+ + GPPH Sbjct: 125 KSLVFSSSATVYGK----PVPAS--GRGPPH 149 >UniRef50_Q7CS52 Cluster: AGR_L_3011p; n=3; Alphaproteobacteria|Rep: AGR_L_3011p - Agrobacterium tumefaciens (strain C58 / ATCC 33970) Length = 356 Score = 34.3 bits (75), Expect = 3.6 Identities = 32/142 (22%), Positives = 56/142 (39%) Frame = +2 Query: 221 DGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKY 400 +GD+ D +A + P VIH AA + ++ ++R N+ + ++L AC Sbjct: 79 EGDILDGVLLKATLREFSPAFVIHCAAN-AYVGESVEDPRKYYRNNVGGSLSLLDACLDQ 137 Query: 401 NVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 580 N+ +V S + PI E P + Y K + ++ Y +YG Sbjct: 138 NIGGLVFSSSCATYGVPQQLPIREETAQM-PVNP----YGRTKLIFEMALEDYAAAYGLR 192 Query: 581 FTSVIPCNVFGPHDNFSLKSSH 646 F ++ N G + L H Sbjct: 193 FVALRYFNAAGADPDGELYERH 214 >UniRef50_Q1YQ08 Cluster: Oxidoreductase; n=1; gamma proteobacterium HTCC2207|Rep: Oxidoreductase - gamma proteobacterium HTCC2207 Length = 336 Score = 34.3 bits (75), Expect = 3.6 Identities = 26/111 (23%), Positives = 45/111 (40%) Frame = +2 Query: 284 VIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTYP 463 +IH AA+V N + D +R N+ N++ A KYNV++ V S + + Sbjct: 76 IIHTAALVS----NALSDADMWRVNVQATANLIAAAEKYNVRRFVQLSSIVAYGNSAAGE 131 Query: 464 IDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGP 616 + E + P H+ Y K + + + P +V+GP Sbjct: 132 LCE----DHPVHADGGSYVLTKLASEHAVLAAHAKGNIEIVIIRPGDVYGP 178 >UniRef50_A7I3Y2 Cluster: Putative zinc protease; n=1; Campylobacter hominis ATCC BAA-381|Rep: Putative zinc protease - Campylobacter hominis (strain ATCC BAA-381 / LMG 19568 / NCTC 13146 /CH001A) Length = 915 Score = 34.3 bits (75), Expect = 3.6 Identities = 26/79 (32%), Positives = 36/79 (45%), Gaps = 8/79 (10%) Frame = +2 Query: 260 FAKHKPTHVIHLAAMVG-----GLFHNMAHNLDFFRENMSINDNILQACHKYN---VKKV 415 F+ + T + LA M+ G F+N N+ EN S+N ++ C +YN KK Sbjct: 537 FSNFENTKIARLAVMISNESGLGGFNNYETNIITANENFSLNKSLNDICVEYNSLSSKKD 596 Query: 416 VSCLSTCIFPDKTTYPIDE 472 VS IF D IDE Sbjct: 597 VSNALKAIFADIKNAKIDE 615 >UniRef50_A4BBD6 Cluster: Putative uncharacterized protein; n=1; Reinekea sp. MED297|Rep: Putative uncharacterized protein - Reinekea sp. MED297 Length = 314 Score = 34.3 bits (75), Expect = 3.6 Identities = 29/118 (24%), Positives = 57/118 (48%), Gaps = 3/118 (2%) Frame = +2 Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 406 D+ D+T + L +H+ THV+HLA+++ + A + +R ++ N+++AC V Sbjct: 49 DINDETLAD-LMREHRITHVVHLASVLEA-SEDRARD---YRIDVDGTRNVIEACLAAGV 103 Query: 407 KKVVSCLSTCIFPDKTTYPIDET-MVHNGPPHSSN--FGYSYAKRMIDVLNRGYNESY 571 + + S + Y D + P N F YS+ KR+++ + Y +S+ Sbjct: 104 EHLTVSSSGAAY----GYHADNAEWLSEADPLRGNYEFAYSWHKRLVEDMLAEYRQSH 157 >UniRef50_A1IBU5 Cluster: Nucleoside-diphosphate-sugar epimerases-like; n=1; Candidatus Desulfococcus oleovorans Hxd3|Rep: Nucleoside-diphosphate-sugar epimerases-like - Candidatus Desulfococcus oleovorans Hxd3 Length = 589 Score = 34.3 bits (75), Expect = 3.6 Identities = 32/121 (26%), Positives = 57/121 (47%), Gaps = 3/121 (2%) Frame = +2 Query: 284 VIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTYP 463 V HLA +VG + + LD N++ + N+ ++C K NV KV+ S+ ++ P Sbjct: 68 VYHLAFIVGQI-QDTQKALDI---NINGSRNVFESCVKNNVSKVIYTSSSTVYGAHADNP 123 Query: 464 IDETMVHNGPPH-SSNFGYSYAKRMIDVLNRGYNESY-GCMFTSVIPCNVFGPH-DNFSL 634 I + P + + Y+ +K ++ R + ++ FT + +FGPH DN Sbjct: 124 IG--FREDAPLRVNEDSYYNESKVKVETFARDFFRNHPDITFTVIRSALLFGPHIDNMFS 181 Query: 635 K 637 K Sbjct: 182 K 182 >UniRef50_Q868I5 Cluster: UDP-N-acetylglucosamine 4-epimerase; n=2; Giardia intestinalis|Rep: UDP-N-acetylglucosamine 4-epimerase - Giardia lamblia (Giardia intestinalis) Length = 385 Score = 34.3 bits (75), Expect = 3.6 Identities = 36/151 (23%), Positives = 64/151 (42%), Gaps = 2/151 (1%) Frame = +2 Query: 224 GDLRDKTQTEALFAK--HKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHK 397 GD+RDK A+F++ K VIHLAA V + ++ + + N+ + N+ Q Sbjct: 63 GDIRDK----AIFSRLPQKIDFVIHLAAAVS-VAESVTNPQKYMLTNVEGSRNVFQYAVD 117 Query: 398 YNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGC 577 V+S + + D I E P+ Y+ +K ++ L + ++ C Sbjct: 118 AKASAVLSASTAAYYGDCGKSAITEAF-----PYGGISPYAESKMEMERLGAEFQKTSRC 172 Query: 578 MFTSVIPCNVFGPHDNFSLKSSHVIPALIRR 670 F NV+GP + S + V+ + R Sbjct: 173 RFIFCRFFNVYGPRQDPSSPYTGVMSIFMDR 203 >UniRef50_Q54WS6 Cluster: Putative dTDP-D-glucose 4,6-dehydratase; n=1; Dictyostelium discoideum AX4|Rep: Putative dTDP-D-glucose 4,6-dehydratase - Dictyostelium discoideum AX4 Length = 434 Score = 34.3 bits (75), Expect = 3.6 Identities = 19/65 (29%), Positives = 32/65 (49%) Frame = +2 Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 403 G++ D E +F K K VIHLAA + ++ ++ F N+ +L+ C Y Sbjct: 67 GNILDSELLENIFEKEKIDIVIHLAAYT-HVDNSFKQSIKFTENNILGTHYLLETCKNYK 125 Query: 404 VKKVV 418 +KK + Sbjct: 126 LKKFI 130 >UniRef50_A0BCG5 Cluster: Chromosome undetermined scaffold_10, whole genome shotgun sequence; n=8; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_10, whole genome shotgun sequence - Paramecium tetraurelia Length = 1051 Score = 34.3 bits (75), Expect = 3.6 Identities = 26/92 (28%), Positives = 44/92 (47%), Gaps = 2/92 (2%) Frame = +2 Query: 293 LAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCI--FPDKTTYPI 466 L AM G F ++ LD F + DNI+ K+N K + S T I +PD+ T Sbjct: 96 LQAMTSGNFPPLSKLLDNFHASEIKEDNIMFQMKKFNKKTLFSGDDTWIGLYPDQFTLQF 155 Query: 467 DETMVHNGPPHSSNFGYSYAKRMIDVLNRGYN 562 + + G HS + ++++ L++GY+ Sbjct: 156 PQKSFNIGDMHSVD--QFNCDKILENLDKGYD 185 >UniRef50_A3LR65 Cluster: Putative dtdp-glucose 4,6-dehydratase; n=1; Pichia stipitis|Rep: Putative dtdp-glucose 4,6-dehydratase - Pichia stipitis (Yeast) Length = 332 Score = 34.3 bits (75), Expect = 3.6 Identities = 34/141 (24%), Positives = 64/141 (45%), Gaps = 3/141 (2%) Frame = +2 Query: 260 FAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCI 439 F ++ T +++ AA + + + L F R N+ + N+L+ C + +K+ S +S + Sbjct: 83 FPINQITDIVNFAAE-SSVDKSFSDPLYFTRNNILVTQNLLE-CMRL-LKQQNSQISVRL 139 Query: 440 FPDKTTYPIDETMVHN---GPPHSSNFGYSYAKRMIDVLNRGYNESYGCMFTSVIPCNVF 610 T ++ + N G +N Y+ K ID++ Y SY T + P N++ Sbjct: 140 LHISTDEVYGDSDILNDEQGRLLPTN-PYAATKASIDLIIHSYQCSYDLSVTIIRPNNIY 198 Query: 611 GPHDNFSLKSSHVIPALIRRM 673 GPH ++P I R+ Sbjct: 199 GPHQ----YPDKIVPVTIERL 215 >UniRef50_Q59083 Cluster: UDP-glucose 4-epimerase; n=14; Bacteria|Rep: UDP-glucose 4-epimerase - Azospirillum brasilense Length = 348 Score = 34.3 bits (75), Expect = 3.6 Identities = 19/84 (22%), Positives = 40/84 (47%) Frame = +2 Query: 221 DGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKY 400 +GD+ + + H+ V+H A + + ++ LD++R N + + +L AC + Sbjct: 57 EGDIGSAELLDRVMRDHRVDAVMHFAGSIV-VPESVVKPLDYYRNNTANSLTLLGACLRA 115 Query: 401 NVKKVVSCLSTCIFPDKTTYPIDE 472 + KVV + ++ + PI E Sbjct: 116 GIDKVVFSSTAAVYGAPESVPIRE 139 >UniRef50_Q2JCE7 Cluster: DTDP-glucose 4,6-dehydratase; n=5; Bacteria|Rep: DTDP-glucose 4,6-dehydratase - Frankia sp. (strain CcI3) Length = 357 Score = 33.9 bits (74), Expect = 4.8 Identities = 38/150 (25%), Positives = 60/150 (40%), Gaps = 1/150 (0%) Frame = +2 Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 403 GD+RD+ E++ +H V++ AA + +FF N+ +L+A Sbjct: 80 GDIRDQELVESVLREHSVDVVVNFAAESHNSLAIIRPG-EFFATNVMGTQTLLEAARTVG 138 Query: 404 VKKVVSCLSTC-IFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 580 V + +STC ++ D D P+ Y+ AK D R Y +Y Sbjct: 139 VARFHQ-ISTCEVYGDMDLN--DPGAFTEDSPYLPRTPYNAAKAGGDHAVRAYGFTYNLP 195 Query: 581 FTSVIPCNVFGPHDNFSLKSSHVIPALIRR 670 T N +GP+ F K VIP + R Sbjct: 196 VTITNCSNNYGPY-QFPEK---VIPLFVTR 221 >UniRef50_Q01T66 Cluster: DTDP-glucose 4,6-dehydratase precursor; n=2; Bacteria|Rep: DTDP-glucose 4,6-dehydratase precursor - Solibacter usitatus (strain Ellin6076) Length = 339 Score = 33.9 bits (74), Expect = 4.8 Identities = 32/133 (24%), Positives = 55/133 (41%), Gaps = 1/133 (0%) Frame = +2 Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 403 GD+ D EA A+ +P ++H AA + ++ R N + +L+A + Sbjct: 57 GDICDAALVEATLAEERPDAIVHFAA-ESHVDRSILSPEPVVRTNYNGTFTLLEAARRQK 115 Query: 404 VKKVVSCLSTCIFPD-KTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCM 580 + + V + ++ + DE V N P S YS +K D+L R Y +Y Sbjct: 116 IARFVHVSTDEVYGSLEAPAEADEAYVLN--PSSP---YSASKAASDLLARSYFVTYKLP 170 Query: 581 FTSVIPCNVFGPH 619 N +GP+ Sbjct: 171 VLITRASNNYGPY 183 >UniRef50_A7HHX8 Cluster: NAD-dependent epimerase/dehydratase; n=4; Cystobacterineae|Rep: NAD-dependent epimerase/dehydratase - Anaeromyxobacter sp. Fw109-5 Length = 317 Score = 33.9 bits (74), Expect = 4.8 Identities = 34/135 (25%), Positives = 60/135 (44%), Gaps = 5/135 (3%) Frame = +2 Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAH-NLDFFRENMSINDNILQACHKYN 403 DLR K + E +F +H+P +IH+ G+ H+ + N+ IL C ++ Sbjct: 61 DLR-KARVEEVFRRHRPEALIHM-----GIMHDPRDPRSEAHSFNVLGTHKILDLCVRHG 114 Query: 404 VKKVVSCLSTCIF---PDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYG 574 VKK V S ++ PD + + +ET + G F +D+ + + + Sbjct: 115 VKKAVVLSSANVYGPRPDNSNFLPEETPLMAG----ERFSEMRDLIELDMYAQSFMWKHP 170 Query: 575 CMFTSVI-PCNVFGP 616 + T V+ P N+ GP Sbjct: 171 ELETVVLRPVNIIGP 185 >UniRef50_A6H035 Cluster: GDP-4-dehydro-D-rhamnose reductase; n=1; Flavobacterium psychrophilum JIP02/86|Rep: GDP-4-dehydro-D-rhamnose reductase - Flavobacterium psychrophilum (strain JIP02/86 / ATCC 49511) Length = 297 Score = 33.9 bits (74), Expect = 4.8 Identities = 30/136 (22%), Positives = 64/136 (47%), Gaps = 3/136 (2%) Frame = +2 Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQAC---HK 397 +L +K + A+ + +P+ VIHLAA + + H + + + N+ N+L+A K Sbjct: 50 NLLEKEKLSAIIKEIQPSIVIHLAA-ISFVGHENLN--EMYDVNVIGTQNLLEAIKNESK 106 Query: 398 YNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGC 577 +++K++ S ++ ++T + E + N H Y +K ++ + + Y ++ Sbjct: 107 DSIRKIIIASSATVYGNQTETVLSEALCPNPVNH-----YGISKLAMEFVAKTYFDTLPI 161 Query: 578 MFTSVIPCNVFGPHDN 625 + T P N P N Sbjct: 162 IITR--PFNYTAPEQN 175 >UniRef50_A3DIS0 Cluster: Polysaccharide biosynthesis protein CapD precursor; n=1; Clostridium thermocellum ATCC 27405|Rep: Polysaccharide biosynthesis protein CapD precursor - Clostridium thermocellum (strain ATCC 27405 / DSM 1237) Length = 607 Score = 33.9 bits (74), Expect = 4.8 Identities = 19/65 (29%), Positives = 33/65 (50%) Frame = +2 Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 403 G +RDK + + +F+++KP V H AA + + + N+ N+ + H+YN Sbjct: 338 GSIRDKKRLDYVFSQYKPGIVFHAAAHKHVPLMEF-NPQEAVKNNVFGTLNVAECAHQYN 396 Query: 404 VKKVV 418 KK V Sbjct: 397 CKKFV 401 >UniRef50_A3CKR6 Cluster: Nucleoside-diphosphate-sugar epimerase, putative; n=2; Streptococcus|Rep: Nucleoside-diphosphate-sugar epimerase, putative - Streptococcus sanguinis (strain SK36) Length = 350 Score = 33.9 bits (74), Expect = 4.8 Identities = 25/124 (20%), Positives = 54/124 (43%), Gaps = 1/124 (0%) Frame = +2 Query: 284 VIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTYP 463 + H AA + H + + N+ +N+L+A ++ +++ V S + + Sbjct: 83 LFHTAAFFRDNYKGGKHWQELYDTNIIGTNNLLEAAYEAGIRQFVHTSSCVVLEGEANQL 142 Query: 464 IDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF-TSVIPCNVFGPHDNFSLKS 640 IDE+M + + F Y +K + + R + + + +F ++P + GP D S Sbjct: 143 IDESMSRS---KDTPFDYYRSKILSEEAVRDFLDKHSDVFGCFILPSVMLGPRDLGPTSS 199 Query: 641 SHVI 652 +I Sbjct: 200 GQMI 203 >UniRef50_A0UVI4 Cluster: NAD-dependent epimerase/dehydratase; n=1; Clostridium cellulolyticum H10|Rep: NAD-dependent epimerase/dehydratase - Clostridium cellulolyticum H10 Length = 309 Score = 33.9 bits (74), Expect = 4.8 Identities = 40/171 (23%), Positives = 70/171 (40%), Gaps = 4/171 (2%) Frame = +2 Query: 221 DGDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSIN----DNILQA 388 +GD+RD + E + V H AA V ++ ++ +E M IN NIL+ Sbjct: 50 EGDIRDSKKIEEVL--EGVDVVFHNAAFV-----SIRNSYTMLKEEMDINCYGTQNILEG 102 Query: 389 CHKYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNES 568 K V+K+V S + PI E + P S Y ++K ++ + + + Sbjct: 103 MVKQRVRKIVFASSMAAYGWPRQIPITEDC--DLAPISP---YGFSKARCELYCKIFAKR 157 Query: 569 YGCMFTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDPTFXSDGE 721 +G + + CN++G S + L ++ A+ T DGE Sbjct: 158 FGISYVILRYCNIYGIKQTL----SPYVGVLTTFINQALSSQPITVNGDGE 204 >UniRef50_A0L9M4 Cluster: NAD-dependent epimerase/dehydratase; n=1; Magnetococcus sp. MC-1|Rep: NAD-dependent epimerase/dehydratase - Magnetococcus sp. (strain MC-1) Length = 330 Score = 33.9 bits (74), Expect = 4.8 Identities = 23/71 (32%), Positives = 41/71 (57%), Gaps = 1/71 (1%) Frame = +2 Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRE-NMSINDNILQACHKYN 403 D+RD+ +ALFA+ + VIHLAA+VG A + ++ N + ++L+A ++ Sbjct: 56 DIRDREAMQALFAQTQFHGVIHLAAIVGD--PACARQSELAQQTNWQASIDLLEASKQHG 113 Query: 404 VKKVVSCLSTC 436 V++ + STC Sbjct: 114 VERFIFA-STC 123 >UniRef50_Q5DAK3 Cluster: SJCHGC01535 protein; n=2; Schistosoma japonicum|Rep: SJCHGC01535 protein - Schistosoma japonicum (Blood fluke) Length = 249 Score = 33.9 bits (74), Expect = 4.8 Identities = 16/45 (35%), Positives = 30/45 (66%), Gaps = 2/45 (4%) Frame = +2 Query: 359 MSINDN--ILQACHKYNVKKVVSCLSTCIFPDKTTYPIDETMVHN 487 +SIND+ I Q+ + Y++ K++S S C+ P++T + E +V+N Sbjct: 141 LSINDSEVIDQSNYVYDIYKMISSQSNCLLPEETIWCSTEDLVNN 185 >UniRef50_Q814Z6 Cluster: UDP-N-acetylglucosamine 4-epimerase; n=1; Bacillus cereus ATCC 14579|Rep: UDP-N-acetylglucosamine 4-epimerase - Bacillus cereus (strain ATCC 14579 / DSM 31) Length = 301 Score = 33.5 bits (73), Expect = 6.3 Identities = 17/63 (26%), Positives = 31/63 (49%) Frame = +2 Query: 284 VIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNVKKVVSCLSTCIFPDKTTYP 463 V+HLAA G + F +N + N+ AC++ N+ +V + + D+T+ P Sbjct: 64 VVHLAATRGS-----QGKISEFHDNEILTQNLYDACYENNISNIVYASTISAYSDETSLP 118 Query: 464 IDE 472 +E Sbjct: 119 WNE 121 >UniRef50_Q7VRZ4 Cluster: Thymidine diphosphoglucose 4,6-dehydratase; n=2; Bordetella|Rep: Thymidine diphosphoglucose 4,6-dehydratase - Bordetella pertussis Length = 326 Score = 33.5 bits (73), Expect = 6.3 Identities = 19/73 (26%), Positives = 34/73 (46%) Frame = +2 Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 403 GD+R +A +H V+H AA+ GL D F N+ +++A ++ Sbjct: 55 GDVRRGADLDAALREHAVDRVVHGAAVTAGLEREKNAAADIFTVNLLGAVKVMEAGLRHG 114 Query: 404 VKKVVSCLSTCIF 442 V++VV + +F Sbjct: 115 VRQVVQLGTGSVF 127 >UniRef50_Q1MP11 Cluster: Nucleoside-diphosphate-sugar epimerases; n=1; Lawsonia intracellularis PHE/MN1-00|Rep: Nucleoside-diphosphate-sugar epimerases - Lawsonia intracellularis (strain PHE/MN1-00) Length = 339 Score = 33.5 bits (73), Expect = 6.3 Identities = 19/69 (27%), Positives = 35/69 (50%) Frame = +2 Query: 227 DLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYNV 406 ++ D + E LF+K+ VIH A + ++ L++++ N + IL+ C KYN Sbjct: 59 NVEDTSMMEVLFSKYTFDAVIHFAG-YKSIAESLKIPLEYYQNNYNSTLTILRLCLKYNS 117 Query: 407 KKVVSCLST 433 + S +T Sbjct: 118 TFIFSSSAT 126 >UniRef50_A5N5N5 Cluster: Predicted nucleoside-diphosphate-sugar epimerase; n=1; Clostridium kluyveri DSM 555|Rep: Predicted nucleoside-diphosphate-sugar epimerase - Clostridium kluyveri DSM 555 Length = 336 Score = 33.5 bits (73), Expect = 6.3 Identities = 38/137 (27%), Positives = 57/137 (41%), Gaps = 4/137 (2%) Frame = +2 Query: 224 GDLRDKTQTEALFAKHKPT--HVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHK 397 GD+ D + F + T +VIH A++V N N N+ NI+ C + Sbjct: 53 GDVTDTESLQKFFTVSESTDIYVIHCASIVT---LNPNPNGKVHAVNVGGTQNIIDKCVE 109 Query: 398 YNVKKVVSCLSTCIFPD-KTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYG 574 + VKK+V ST P+ PI E + H G + YS K L Y Sbjct: 110 HQVKKLVYISSTGAIPELPGNMPIKE-VTHFGIEGLVGY-YSVTKAEASQLVIDALAKYP 167 Query: 575 CMFTSVI-PCNVFGPHD 622 + S++ P + GP+D Sbjct: 168 QLDASLVHPSGICGPND 184 >UniRef50_A3ZSY0 Cluster: CDP glucose 4,6-dehydratase; n=1; Blastopirellula marina DSM 3645|Rep: CDP glucose 4,6-dehydratase - Blastopirellula marina DSM 3645 Length = 368 Score = 33.5 bits (73), Expect = 6.3 Identities = 30/119 (25%), Positives = 53/119 (44%), Gaps = 3/119 (2%) Frame = +2 Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAM-VGGLFHNMAHNLDFFRENMSINDNILQACHKY 400 GD+RD ++ + +F P V+HLAA + L + + L+ F N+ N+L+AC Sbjct: 67 GDIRDLSKLKQVFQDFDPEIVLHLAAQPLVRLSYEIP--LETFDVNVLGTANVLEACRGL 124 Query: 401 NVKKVVSCLST--CIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESY 571 + ++T C + + ET P YS +K +++ Y +SY Sbjct: 125 QSLQAAVMVTTDKCYENREWDWSYRET-----DPLGGKDPYSASKACAEIVTSSYRDSY 178 >UniRef50_Q9HSU9 Cluster: GDP-D-mannose dehydratase; n=2; Halobacterium salinarum|Rep: GDP-D-mannose dehydratase - Halobacterium salinarium (Halobacterium halobium) Length = 309 Score = 33.5 bits (73), Expect = 6.3 Identities = 30/115 (26%), Positives = 49/115 (42%) Frame = +2 Query: 377 ILQACHKYNVKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRG 556 ++ A + +V VV S I+ T+P E+M P S Y+ +K + L Sbjct: 104 VIDAAREADVDTVVVASSAAIYGSTETFPKVESMTEQ--PESP---YALSKHYTEKLALQ 158 Query: 557 YNESYGCMFTSVIPCNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDPTFXSDGE 721 +E Y ++ N++GP + + + VIP I M D + P DGE Sbjct: 159 ASELYDIDTAALRYFNIYGPRQDPNGDYAAVIPKFISLMLDGER---PVIYGDGE 210 >UniRef50_A4FIG8 Cluster: Modular polyketide synthase; n=1; Saccharopolyspora erythraea NRRL 2338|Rep: Modular polyketide synthase - Saccharopolyspora erythraea (strain NRRL 23338) Length = 571 Score = 33.1 bits (72), Expect = 8.4 Identities = 16/46 (34%), Positives = 24/46 (52%), Gaps = 1/46 (2%) Frame = +2 Query: 599 CNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDPTF-XSDGEAXNH 733 C F P + ++ V+ +I+R+DDA+ GDP G A NH Sbjct: 224 CRPFSPDADGYVRGEGVLCFVIKRLDDALDSGDPVLAVIRGAAANH 269 >UniRef50_Q2U1I6 Cluster: Polyketide synthase modules and related proteins; n=1; Aspergillus oryzae|Rep: Polyketide synthase modules and related proteins - Aspergillus oryzae Length = 2407 Score = 33.1 bits (72), Expect = 8.4 Identities = 16/47 (34%), Positives = 26/47 (55%), Gaps = 1/47 (2%) Frame = +2 Query: 599 CNVFGPHDNFSLKSSHVIPALIRRMDDAMQKGDP-TFXSDGEAXNHS 736 C+ F + +K+ + +++R+DDA+Q GDP G A NHS Sbjct: 236 CHTFDAKADGYIKAEGINAVILKRLDDAIQDGDPIRAVIRGTANNHS 282 >UniRef50_A5DWB0 Cluster: Putative uncharacterized protein; n=2; Saccharomycetales|Rep: Putative uncharacterized protein - Lodderomyces elongisporus (Yeast) (Saccharomyces elongisporus) Length = 328 Score = 33.1 bits (72), Expect = 8.4 Identities = 14/35 (40%), Positives = 22/35 (62%) Frame = +2 Query: 515 YSYAKRMIDVLNRGYNESYGCMFTSVIPCNVFGPH 619 YS +K + D+L + Y +S+ T + P NVFGP+ Sbjct: 157 YSASKALADLLIQAYKQSFQLPITIIRPNNVFGPN 191 >UniRef50_A2R6J0 Cluster: Catalytic activity: dTDPglucose = dTDP-4-dehydro-6-deoxy-D-glucose + H2O; n=1; Aspergillus niger|Rep: Catalytic activity: dTDPglucose = dTDP-4-dehydro-6-deoxy-D-glucose + H2O - Aspergillus niger Length = 362 Score = 33.1 bits (72), Expect = 8.4 Identities = 32/131 (24%), Positives = 53/131 (40%) Frame = +2 Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 403 GDL D+ + ALF + K V+H AA + ++ + L F R N++ +L+A + Sbjct: 81 GDLCDRDRVTALFQQFKVDAVVHFAAN-SHVDQSLVNPLSFTRSNVTGTHVLLEAARQAG 139 Query: 404 VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 583 +ST D + +N YS +K +++ Y S+ Sbjct: 140 TVIRFIHISTDEVYGGNMPGQDYAFTEEDQLNPTN-PYSASKAAAEMIANSYRYSFHMPI 198 Query: 584 TSVIPCNVFGP 616 NVFGP Sbjct: 199 IITRCNNVFGP 209 >UniRef50_O95455 Cluster: dTDP-D-glucose 4,6-dehydratase; n=24; Eumetazoa|Rep: dTDP-D-glucose 4,6-dehydratase - Homo sapiens (Human) Length = 350 Score = 33.1 bits (72), Expect = 8.4 Identities = 30/132 (22%), Positives = 52/132 (39%) Frame = +2 Query: 224 GDLRDKTQTEALFAKHKPTHVIHLAAMVGGLFHNMAHNLDFFRENMSINDNILQACHKYN 403 GD+ D + LF K V+H AA + + +F N+ ++ A H+ Sbjct: 75 GDICDSHFVKLLFETEKIDIVLHFAAQTH-VDLSFVRAFEFTYVNVYGTHVLVSAAHEAR 133 Query: 404 VKKVVSCLSTCIFPDKTTYPIDETMVHNGPPHSSNFGYSYAKRMIDVLNRGYNESYGCMF 583 V+K + + ++ DE+ P +N Y+ +K + + Y E Y Sbjct: 134 VEKFIYVSTDEVYGGSLDKEFDES----SPKQPTN-PYASSKAAAECFVQSYWEQYKFPV 188 Query: 584 TSVIPCNVFGPH 619 NV+GPH Sbjct: 189 VITRSSNVYGPH 200 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 809,157,277 Number of Sequences: 1657284 Number of extensions: 16371747 Number of successful extensions: 35926 Number of sequences better than 10.0: 182 Number of HSP's better than 10.0 without gapping: 34609 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 35837 length of database: 575,637,011 effective HSP length: 99 effective length of database: 411,565,895 effective search space used: 68731504465 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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