Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= br--1926
(772 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
L16991-1|AAA21719.1| 212|Homo sapiens thymidylate kinase protein. 97 5e-20
CR542015-1|CAG46812.1| 212|Homo sapiens DTYMK protein. 97 5e-20
BC001827-1|AAH01827.1| 212|Homo sapiens deoxythymidylate kinase... 97 5e-20
AK223434-1|BAD97154.1| 212|Homo sapiens deoxythymidylate kinase... 97 5e-20
AC133528-2|AAY14920.1| 212|Homo sapiens unknown protein. 97 5e-20
X54729-1|CAA38528.1| 211|Homo sapiens thymidylate kinase protein. 96 1e-19
CR541986-1|CAG46783.1| 212|Homo sapiens DTYMK protein. 96 1e-19
X99802-1|CAA68137.1| 766|Homo sapiens ZYG homologue protein. 31 4.6
BC052563-1|AAH52563.1| 766|Homo sapiens zer-1 homolog (C. elega... 31 4.6
AL441992-7|CAI15407.1| 766|Homo sapiens zer-1 homolog (C. elega... 31 4.6
BC141802-1|AAI41803.1| 409|Homo sapiens LOC129607 protein protein. 31 6.0
BC132821-1|AAI32822.1| 366|Homo sapiens LOC129607 protein protein. 31 6.0
BC089425-1|AAH89425.1| 441|Homo sapiens LOC129607 protein protein. 31 6.0
BC065375-1|AAH65375.1| 458|Homo sapiens secretion regulating gu... 31 6.0
AJ243951-1|CAB60833.1| 288|Homo sapiens deafness locus associat... 31 6.0
AJ243950-1|CAB60832.1| 458|Homo sapiens deafness locus associat... 31 6.0
>L16991-1|AAA21719.1| 212|Homo sapiens thymidylate kinase protein.
Length = 212
Score = 97.5 bits (232), Expect = 5e-20
Identities = 43/82 (52%), Positives = 59/82 (71%), Gaps = 1/82 (1%)
Frame = +2
Query: 263 AEYRNFPARETEIGKVINNYLSSKNELSDEAIHLLFSANRWERAQNIIKTLEGGTTIVLD 442
AE FP R TEIGK++++YL K+++ D ++HLLFSANRWE+ I + L G T+V+D
Sbjct: 37 AELLRFPERSTEIGKLLSSYLKKKSDVEDHSVHLLFSANRWEQVPLIKEKLSQGVTLVVD 96
Query: 443 RYCYSGVAFSAAK-GLDLNWCK 505
RY +SGVAF+ AK L+WCK
Sbjct: 97 RYAFSGVAFTGAKENFSLDWCK 118
Score = 59.3 bits (137), Expect = 2e-08
Identities = 27/84 (32%), Positives = 50/84 (59%), Gaps = 3/84 (3%)
Frame = +1
Query: 472 SSKRFRSELVQVSDAGLPQPDKVFFLTMPLEAVLKRNGFGNERYEVVDFQKKVWNIYSKL 651
+ + F + + D GLP+PD V FL + L KR FG+ERYE FQ++ + +L
Sbjct: 108 AKENFSLDWCKQPDVGLPKPDLVLFLQLQLADAAKRGAFGHERYENGAFQERALRCFHQL 167
Query: 652 IEP---NWDVLDANRTMDAIQTDI 714
++ NW ++DA+++++A+ ++
Sbjct: 168 MKDTTLNWKMVDASKSIEAVHEEL 191
Score = 43.6 bits (98), Expect = 8e-04
Identities = 19/27 (70%), Positives = 24/27 (88%)
Frame = +3
Query: 165 KRGALIVIEGIDRTGKSTQGKILVESL 245
+RGALIV+EG+DR GKSTQ + LVE+L
Sbjct: 4 RRGALIVLEGVDRAGKSTQSRKLVEAL 30
>CR542015-1|CAG46812.1| 212|Homo sapiens DTYMK protein.
Length = 212
Score = 97.5 bits (232), Expect = 5e-20
Identities = 43/82 (52%), Positives = 59/82 (71%), Gaps = 1/82 (1%)
Frame = +2
Query: 263 AEYRNFPARETEIGKVINNYLSSKNELSDEAIHLLFSANRWERAQNIIKTLEGGTTIVLD 442
AE FP R TEIGK++++YL K+++ D ++HLLFSANRWE+ I + L G T+V+D
Sbjct: 37 AELLRFPERSTEIGKLLSSYLQKKSDVEDHSVHLLFSANRWEQVPLIKEKLSQGVTLVVD 96
Query: 443 RYCYSGVAFSAAK-GLDLNWCK 505
RY +SGVAF+ AK L+WCK
Sbjct: 97 RYAFSGVAFTGAKENFSLDWCK 118
Score = 61.7 bits (143), Expect = 3e-09
Identities = 29/84 (34%), Positives = 50/84 (59%), Gaps = 3/84 (3%)
Frame = +1
Query: 472 SSKRFRSELVQVSDAGLPQPDKVFFLTMPLEAVLKRNGFGNERYEVVDFQKKVWNIYSKL 651
+ + F + + D GLP+PD V FL + L KR FG+ERYE FQ++ + +L
Sbjct: 108 AKENFSLDWCKQPDVGLPKPDLVLFLQLQLADAAKRGAFGHERYENGAFQERALRCFHQL 167
Query: 652 IEP---NWDVLDANRTMDAIQTDI 714
++ NW ++DA+++++A+ DI
Sbjct: 168 MKDTTLNWKMVDASKSIEAVHEDI 191
Score = 43.6 bits (98), Expect = 8e-04
Identities = 19/27 (70%), Positives = 24/27 (88%)
Frame = +3
Query: 165 KRGALIVIEGIDRTGKSTQGKILVESL 245
+RGALIV+EG+DR GKSTQ + LVE+L
Sbjct: 4 RRGALIVLEGVDRAGKSTQSRKLVEAL 30
>BC001827-1|AAH01827.1| 212|Homo sapiens deoxythymidylate kinase
(thymidylate kinase) protein.
Length = 212
Score = 97.5 bits (232), Expect = 5e-20
Identities = 43/82 (52%), Positives = 59/82 (71%), Gaps = 1/82 (1%)
Frame = +2
Query: 263 AEYRNFPARETEIGKVINNYLSSKNELSDEAIHLLFSANRWERAQNIIKTLEGGTTIVLD 442
AE FP R TEIGK++++YL K+++ D ++HLLFSANRWE+ I + L G T+V+D
Sbjct: 37 AELLRFPERSTEIGKLLSSYLQKKSDVEDHSVHLLFSANRWEQVPLIKEKLSQGVTLVVD 96
Query: 443 RYCYSGVAFSAAK-GLDLNWCK 505
RY +SGVAF+ AK L+WCK
Sbjct: 97 RYAFSGVAFTGAKENFSLDWCK 118
Score = 61.7 bits (143), Expect = 3e-09
Identities = 29/84 (34%), Positives = 50/84 (59%), Gaps = 3/84 (3%)
Frame = +1
Query: 472 SSKRFRSELVQVSDAGLPQPDKVFFLTMPLEAVLKRNGFGNERYEVVDFQKKVWNIYSKL 651
+ + F + + D GLP+PD V FL + L KR FG+ERYE FQ++ + +L
Sbjct: 108 AKENFSLDWCKQPDVGLPKPDLVLFLQLQLADAAKRGAFGHERYENGAFQERALRCFHQL 167
Query: 652 IEP---NWDVLDANRTMDAIQTDI 714
++ NW ++DA+++++A+ DI
Sbjct: 168 MKDTTLNWKMVDASKSIEAVHEDI 191
Score = 43.6 bits (98), Expect = 8e-04
Identities = 19/27 (70%), Positives = 24/27 (88%)
Frame = +3
Query: 165 KRGALIVIEGIDRTGKSTQGKILVESL 245
+RGALIV+EG+DR GKSTQ + LVE+L
Sbjct: 4 RRGALIVLEGVDRAGKSTQSRKLVEAL 30
>AK223434-1|BAD97154.1| 212|Homo sapiens deoxythymidylate kinase
(thymidylate kinase) variant protein.
Length = 212
Score = 97.5 bits (232), Expect = 5e-20
Identities = 43/82 (52%), Positives = 59/82 (71%), Gaps = 1/82 (1%)
Frame = +2
Query: 263 AEYRNFPARETEIGKVINNYLSSKNELSDEAIHLLFSANRWERAQNIIKTLEGGTTIVLD 442
AE FP R TEIGK++++YL K+++ D ++HLLFSANRWE+ I + L G T+V+D
Sbjct: 37 AELLRFPERSTEIGKLLSSYLQKKSDVEDHSVHLLFSANRWEQVPLIKEKLSQGVTLVVD 96
Query: 443 RYCYSGVAFSAAK-GLDLNWCK 505
RY +SGVAF+ AK L+WCK
Sbjct: 97 RYAFSGVAFTGAKENFSLDWCK 118
Score = 61.7 bits (143), Expect = 3e-09
Identities = 29/84 (34%), Positives = 50/84 (59%), Gaps = 3/84 (3%)
Frame = +1
Query: 472 SSKRFRSELVQVSDAGLPQPDKVFFLTMPLEAVLKRNGFGNERYEVVDFQKKVWNIYSKL 651
+ + F + + D GLP+PD V FL + L KR FG+ERYE FQ++ + +L
Sbjct: 108 AKENFSLDWCKQPDVGLPKPDLVLFLQLQLADAAKRGAFGHERYENGAFQERALRCFHQL 167
Query: 652 IEP---NWDVLDANRTMDAIQTDI 714
++ NW ++DA+++++A+ DI
Sbjct: 168 MKDTTLNWKMVDASKSIEAVHEDI 191
Score = 40.7 bits (91), Expect = 0.006
Identities = 18/27 (66%), Positives = 23/27 (85%)
Frame = +3
Query: 165 KRGALIVIEGIDRTGKSTQGKILVESL 245
+RGALIV+EG+ R GKSTQ + LVE+L
Sbjct: 4 RRGALIVLEGVGRAGKSTQSRKLVEAL 30
>AC133528-2|AAY14920.1| 212|Homo sapiens unknown protein.
Length = 212
Score = 97.5 bits (232), Expect = 5e-20
Identities = 43/82 (52%), Positives = 59/82 (71%), Gaps = 1/82 (1%)
Frame = +2
Query: 263 AEYRNFPARETEIGKVINNYLSSKNELSDEAIHLLFSANRWERAQNIIKTLEGGTTIVLD 442
AE FP R TEIGK++++YL K+++ D ++HLLFSANRWE+ I + L G T+V+D
Sbjct: 37 AELLRFPERSTEIGKLLSSYLQKKSDVEDHSVHLLFSANRWEQVPLIKEKLSQGVTLVVD 96
Query: 443 RYCYSGVAFSAAK-GLDLNWCK 505
RY +SGVAF+ AK L+WCK
Sbjct: 97 RYAFSGVAFTGAKENFSLDWCK 118
Score = 61.7 bits (143), Expect = 3e-09
Identities = 29/84 (34%), Positives = 50/84 (59%), Gaps = 3/84 (3%)
Frame = +1
Query: 472 SSKRFRSELVQVSDAGLPQPDKVFFLTMPLEAVLKRNGFGNERYEVVDFQKKVWNIYSKL 651
+ + F + + D GLP+PD V FL + L KR FG+ERYE FQ++ + +L
Sbjct: 108 AKENFSLDWCKQPDVGLPKPDLVLFLQLQLADAAKRGAFGHERYENGAFQERALRCFHQL 167
Query: 652 IEP---NWDVLDANRTMDAIQTDI 714
++ NW ++DA+++++A+ DI
Sbjct: 168 MKDTTLNWKMVDASKSIEAVHEDI 191
Score = 43.6 bits (98), Expect = 8e-04
Identities = 19/27 (70%), Positives = 24/27 (88%)
Frame = +3
Query: 165 KRGALIVIEGIDRTGKSTQGKILVESL 245
+RGALIV+EG+DR GKSTQ + LVE+L
Sbjct: 4 RRGALIVLEGVDRAGKSTQSRKLVEAL 30
>X54729-1|CAA38528.1| 211|Homo sapiens thymidylate kinase protein.
Length = 211
Score = 95.9 bits (228), Expect = 1e-19
Identities = 42/81 (51%), Positives = 58/81 (71%), Gaps = 1/81 (1%)
Frame = +2
Query: 266 EYRNFPARETEIGKVINNYLSSKNELSDEAIHLLFSANRWERAQNIIKTLEGGTTIVLDR 445
E FP R TEIGK++++YL K+++ D ++HLLFSANRWE+ I + L G T+V+DR
Sbjct: 37 ELLRFPERSTEIGKLLSSYLQKKSDVEDHSVHLLFSANRWEQVPLIKEKLSQGVTLVVDR 96
Query: 446 YCYSGVAFSAAK-GLDLNWCK 505
Y +SGVAF+ AK L+WCK
Sbjct: 97 YAFSGVAFTGAKENFSLDWCK 117
Score = 58.8 bits (136), Expect = 2e-08
Identities = 27/84 (32%), Positives = 49/84 (58%), Gaps = 3/84 (3%)
Frame = +1
Query: 472 SSKRFRSELVQVSDAGLPQPDKVFFLTMPLEAVLKRNGFGNERYEVVDFQKKVWNIYSKL 651
+ + F + + D GLP+PD V FL + L KR FG+ERYE FQ++ + +L
Sbjct: 107 AKENFSLDWCKQPDVGLPKPDLVLFLQLQLADAAKRGAFGHERYENGAFQERALRCFHQL 166
Query: 652 IEP---NWDVLDANRTMDAIQTDI 714
++ NW ++DA++ ++A+ ++
Sbjct: 167 MKDTTLNWKMVDASKRLEAVHEEL 190
Score = 44.4 bits (100), Expect = 5e-04
Identities = 19/29 (65%), Positives = 25/29 (86%)
Frame = +3
Query: 165 KRGALIVIEGIDRTGKSTQGKILVESLKK 251
+RGALIV+EG+DR GKSTQ + LVE+L +
Sbjct: 4 RRGALIVLEGVDRAGKSTQSRKLVEALSR 32
>CR541986-1|CAG46783.1| 212|Homo sapiens DTYMK protein.
Length = 212
Score = 95.9 bits (228), Expect = 1e-19
Identities = 43/82 (52%), Positives = 58/82 (70%), Gaps = 1/82 (1%)
Frame = +2
Query: 263 AEYRNFPARETEIGKVINNYLSSKNELSDEAIHLLFSANRWERAQNIIKTLEGGTTIVLD 442
AE FP R TEIGK++++YL K+++ D + HLLFSANRWE+ I + L G T+V+D
Sbjct: 37 AELLRFPERSTEIGKLLSSYLQKKSDVEDHSAHLLFSANRWEQVPLIKEKLSQGVTLVVD 96
Query: 443 RYCYSGVAFSAAK-GLDLNWCK 505
RY +SGVAF+ AK L+WCK
Sbjct: 97 RYAFSGVAFTGAKENFSLDWCK 118
Score = 61.7 bits (143), Expect = 3e-09
Identities = 29/84 (34%), Positives = 50/84 (59%), Gaps = 3/84 (3%)
Frame = +1
Query: 472 SSKRFRSELVQVSDAGLPQPDKVFFLTMPLEAVLKRNGFGNERYEVVDFQKKVWNIYSKL 651
+ + F + + D GLP+PD V FL + L KR FG+ERYE FQ++ + +L
Sbjct: 108 AKENFSLDWCKQPDVGLPKPDLVLFLQLQLADAAKRGAFGHERYENGAFQERALRCFHQL 167
Query: 652 IEP---NWDVLDANRTMDAIQTDI 714
++ NW ++DA+++++A+ DI
Sbjct: 168 MKDTTLNWKMVDASKSIEAVHEDI 191
Score = 43.6 bits (98), Expect = 8e-04
Identities = 19/27 (70%), Positives = 24/27 (88%)
Frame = +3
Query: 165 KRGALIVIEGIDRTGKSTQGKILVESL 245
+RGALIV+EG+DR GKSTQ + LVE+L
Sbjct: 4 RRGALIVLEGVDRAGKSTQSRKLVEAL 30
>X99802-1|CAA68137.1| 766|Homo sapiens ZYG homologue protein.
Length = 766
Score = 31.1 bits (67), Expect = 4.6
Identities = 16/55 (29%), Positives = 27/55 (49%)
Frame = +2
Query: 254 HIEAEYRNFPARETEIGKVINNYLSSKNELSDEAIHLLFSANRWERAQNIIKTLE 418
HI A + E ++ I Y + E++ AI+LLF R ER +++ L+
Sbjct: 341 HIPAYKVSGDKNEEQVLNAIEAYTEHRPEITSRAINLLFDIARIERCNQLLRALK 395
>BC052563-1|AAH52563.1| 766|Homo sapiens zer-1 homolog (C. elegans)
protein.
Length = 766
Score = 31.1 bits (67), Expect = 4.6
Identities = 16/55 (29%), Positives = 27/55 (49%)
Frame = +2
Query: 254 HIEAEYRNFPARETEIGKVINNYLSSKNELSDEAIHLLFSANRWERAQNIIKTLE 418
HI A + E ++ I Y + E++ AI+LLF R ER +++ L+
Sbjct: 341 HIPAYKVSGDKNEEQVLNAIEAYTEHRPEITSRAINLLFDIARIERCNQLLRALK 395
>AL441992-7|CAI15407.1| 766|Homo sapiens zer-1 homolog (C. elegans)
protein.
Length = 766
Score = 31.1 bits (67), Expect = 4.6
Identities = 16/55 (29%), Positives = 27/55 (49%)
Frame = +2
Query: 254 HIEAEYRNFPARETEIGKVINNYLSSKNELSDEAIHLLFSANRWERAQNIIKTLE 418
HI A + E ++ I Y + E++ AI+LLF R ER +++ L+
Sbjct: 341 HIPAYKVSGDKNEEQVLNAIEAYTEHRPEITSRAINLLFDIARIERCNQLLRALK 395
>BC141802-1|AAI41803.1| 409|Homo sapiens LOC129607 protein protein.
Length = 409
Score = 30.7 bits (66), Expect = 6.0
Identities = 15/38 (39%), Positives = 23/38 (60%)
Frame = +3
Query: 150 KTINMKRGALIVIEGIDRTGKSTQGKILVESLKKHTLK 263
K I + ++ IEG+D TGK+T + + +SLK LK
Sbjct: 245 KQIQKGKFQVVAIEGLDATGKTTVTQSVADSLKAVLLK 282
>BC132821-1|AAI32822.1| 366|Homo sapiens LOC129607 protein protein.
Length = 366
Score = 30.7 bits (66), Expect = 6.0
Identities = 15/38 (39%), Positives = 23/38 (60%)
Frame = +3
Query: 150 KTINMKRGALIVIEGIDRTGKSTQGKILVESLKKHTLK 263
K I + ++ IEG+D TGK+T + + +SLK LK
Sbjct: 245 KQIQKGKFQVVAIEGLDATGKTTVTQSVADSLKAVLLK 282
>BC089425-1|AAH89425.1| 441|Homo sapiens LOC129607 protein protein.
Length = 441
Score = 30.7 bits (66), Expect = 6.0
Identities = 15/38 (39%), Positives = 23/38 (60%)
Frame = +3
Query: 150 KTINMKRGALIVIEGIDRTGKSTQGKILVESLKKHTLK 263
K I + ++ IEG+D TGK+T + + +SLK LK
Sbjct: 237 KQIQKGKFQVVAIEGLDATGKTTVTQSVADSLKAVLLK 274
>BC065375-1|AAH65375.1| 458|Homo sapiens secretion regulating
guanine nucleotide exchange factor protein.
Length = 458
Score = 30.7 bits (66), Expect = 6.0
Identities = 17/45 (37%), Positives = 23/45 (51%), Gaps = 1/45 (2%)
Frame = +3
Query: 174 ALIVIEGIDRTGKSTQ-GKILVESLKKHTLKLNTEIFLPVRQKLE 305
A+ V+ G D + T G++ V KH N FLPV QK+E
Sbjct: 214 AMCVLAGSDHSASLTDAGEVYVWGSNKHGQLANEAAFLPVPQKIE 258
>AJ243951-1|CAB60833.1| 288|Homo sapiens deafness locus associated
putative guanine nucleotide exchange factor protein.
Length = 288
Score = 30.7 bits (66), Expect = 6.0
Identities = 17/45 (37%), Positives = 23/45 (51%), Gaps = 1/45 (2%)
Frame = +3
Query: 174 ALIVIEGIDRTGKSTQ-GKILVESLKKHTLKLNTEIFLPVRQKLE 305
A+ V+ G D + T G++ V KH N FLPV QK+E
Sbjct: 214 AMCVLAGSDHSASLTDAGEVYVWGSNKHGQLANEAAFLPVPQKIE 258
>AJ243950-1|CAB60832.1| 458|Homo sapiens deafness locus associated
putative guanine nucleotide exchange factor protein.
Length = 458
Score = 30.7 bits (66), Expect = 6.0
Identities = 17/45 (37%), Positives = 23/45 (51%), Gaps = 1/45 (2%)
Frame = +3
Query: 174 ALIVIEGIDRTGKSTQ-GKILVESLKKHTLKLNTEIFLPVRQKLE 305
A+ V+ G D + T G++ V KH N FLPV QK+E
Sbjct: 214 AMCVLAGSDHSASLTDAGEVYVWGSNKHGQLANEAAFLPVPQKIE 258
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 105,996,562
Number of Sequences: 237096
Number of extensions: 2148873
Number of successful extensions: 7564
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 7424
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7563
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9311505506
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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