Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= br--1603
(745 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC003547-1|AAH03547.1| 352|Homo sapiens sirtuin (silent mating ... 98 3e-20
BC003012-1|AAH03012.1| 352|Homo sapiens sirtuin (silent mating ... 98 3e-20
AY030277-1|AAK51133.1| 352|Homo sapiens SIRT2 protein. 98 3e-20
AJ505014-1|CAD43717.1| 369|Homo sapiens sirtuin type 2 protein. 98 3e-20
AF160214-1|AAF67015.1| 373|Homo sapiens silent information regu... 98 3e-20
AF095714-1|AAD45971.1| 352|Homo sapiens silencing information r... 98 3e-20
AF083107-1|AAD40850.2| 389|Homo sapiens sirtuin type 2 protein. 98 3e-20
BC001042-1|AAH01042.1| 399|Homo sapiens sirtuin (silent mating ... 60 1e-08
AL137276-1|CAB70674.1| 118|Homo sapiens hypothetical protein pr... 60 1e-08
AF083108-1|AAD40851.1| 399|Homo sapiens sirtuin type 3 protein. 60 1e-08
DQ278604-1|ABB72675.1| 747|Homo sapiens sirtuin (silent mating ... 41 0.004
BC012499-1|AAH12499.1| 555|Homo sapiens SIRT1 protein protein. 41 0.004
AL133551-8|CAI16036.1| 747|Homo sapiens sirtuin (silent mating ... 41 0.004
AF235040-1|AAG38486.1| 747|Homo sapiens SIR2alpha protein protein. 41 0.004
AF083106-1|AAD40849.2| 747|Homo sapiens sirtuin type 1 protein. 41 0.004
BC008744-1|AAH08744.2| 440|Homo sapiens PLEKHQ1 protein protein. 31 3.3
AF494534-1|AAM18053.1| 490|Homo sapiens PH domain containing pr... 31 3.3
U88713-1|AAC51916.1| 700|Homo sapiens phosphodiesterase 4C prot... 31 5.8
BC039897-1|AAH39897.1| 596|Homo sapiens PTPN5 protein protein. 31 5.8
BC117319-1|AAI17320.1| 257|Homo sapiens TPRXL protein protein. 30 7.6
AB202103-3|BAE78626.1| 152|Homo sapiens chromosome 6 open readi... 30 7.6
>BC003547-1|AAH03547.1| 352|Homo sapiens sirtuin (silent mating
type information regulation 2 homolog) 2 (S. cerevisiae)
protein.
Length = 352
Score = 98.3 bits (234), Expect = 3e-20
Identities = 48/88 (54%), Positives = 63/88 (71%), Gaps = 1/88 (1%)
Frame = +1
Query: 1 DMLIIMGSSLEVQPFASLIDMVPDSCPRLLINREKAGVRPPILRIRGLMCGGLQLD-EGS 177
D+L++MG+SL+VQPFASLI P S PRLLIN+EKAG P L + + GG+ D + +
Sbjct: 218 DLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAGQSDPFLGMIMGLGGGMDFDSKKA 277
Query: 178 YRDVARLGDCDEGCQDLADRLGWGDDFE 261
YRDVA LG+CD+GC LA+ LGW + E
Sbjct: 278 YRDVAWLGECDQGCLALAELLGWKKELE 305
>BC003012-1|AAH03012.1| 352|Homo sapiens sirtuin (silent mating
type information regulation 2 homolog) 2 (S. cerevisiae)
protein.
Length = 352
Score = 98.3 bits (234), Expect = 3e-20
Identities = 48/88 (54%), Positives = 63/88 (71%), Gaps = 1/88 (1%)
Frame = +1
Query: 1 DMLIIMGSSLEVQPFASLIDMVPDSCPRLLINREKAGVRPPILRIRGLMCGGLQLD-EGS 177
D+L++MG+SL+VQPFASLI P S PRLLIN+EKAG P L + + GG+ D + +
Sbjct: 218 DLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAGQSDPFLGMIMGLGGGMDFDSKKA 277
Query: 178 YRDVARLGDCDEGCQDLADRLGWGDDFE 261
YRDVA LG+CD+GC LA+ LGW + E
Sbjct: 278 YRDVAWLGECDQGCLALAELLGWKKELE 305
>AY030277-1|AAK51133.1| 352|Homo sapiens SIRT2 protein.
Length = 352
Score = 98.3 bits (234), Expect = 3e-20
Identities = 48/88 (54%), Positives = 63/88 (71%), Gaps = 1/88 (1%)
Frame = +1
Query: 1 DMLIIMGSSLEVQPFASLIDMVPDSCPRLLINREKAGVRPPILRIRGLMCGGLQLD-EGS 177
D+L++MG+SL+VQPFASLI P S PRLLIN+EKAG P L + + GG+ D + +
Sbjct: 218 DLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAGQSDPFLGMIMGLGGGMDFDSKKA 277
Query: 178 YRDVARLGDCDEGCQDLADRLGWGDDFE 261
YRDVA LG+CD+GC LA+ LGW + E
Sbjct: 278 YRDVAWLGECDQGCLALAELLGWKKELE 305
>AJ505014-1|CAD43717.1| 369|Homo sapiens sirtuin type 2 protein.
Length = 369
Score = 98.3 bits (234), Expect = 3e-20
Identities = 48/88 (54%), Positives = 63/88 (71%), Gaps = 1/88 (1%)
Frame = +1
Query: 1 DMLIIMGSSLEVQPFASLIDMVPDSCPRLLINREKAGVRPPILRIRGLMCGGLQLD-EGS 177
D+L++MG+SL+VQPFASLI P S PRLLIN+EKAG P L + + GG+ D + +
Sbjct: 235 DLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAGQSDPFLGMIMGLGGGMDFDSKKA 294
Query: 178 YRDVARLGDCDEGCQDLADRLGWGDDFE 261
YRDVA LG+CD+GC LA+ LGW + E
Sbjct: 295 YRDVAWLGECDQGCLALAELLGWKKELE 322
>AF160214-1|AAF67015.1| 373|Homo sapiens silent information
regulator 2 homolog protein.
Length = 373
Score = 98.3 bits (234), Expect = 3e-20
Identities = 48/88 (54%), Positives = 63/88 (71%), Gaps = 1/88 (1%)
Frame = +1
Query: 1 DMLIIMGSSLEVQPFASLIDMVPDSCPRLLINREKAGVRPPILRIRGLMCGGLQLD-EGS 177
D+L++MG+SL+VQPFASLI P S PRLLIN+EKAG P L + + GG+ D + +
Sbjct: 239 DLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAGQSDPFLGMIMGLGGGMDFDSKKA 298
Query: 178 YRDVARLGDCDEGCQDLADRLGWGDDFE 261
YRDVA LG+CD+GC LA+ LGW + E
Sbjct: 299 YRDVAWLGECDQGCLALAELLGWKKELE 326
>AF095714-1|AAD45971.1| 352|Homo sapiens silencing information
regulator 2-like protein protein.
Length = 352
Score = 98.3 bits (234), Expect = 3e-20
Identities = 48/88 (54%), Positives = 63/88 (71%), Gaps = 1/88 (1%)
Frame = +1
Query: 1 DMLIIMGSSLEVQPFASLIDMVPDSCPRLLINREKAGVRPPILRIRGLMCGGLQLD-EGS 177
D+L++MG+SL+VQPFASLI P S PRLLIN+EKAG P L + + GG+ D + +
Sbjct: 218 DLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAGQSDPFLGMIMGLGGGMDFDSKKA 277
Query: 178 YRDVARLGDCDEGCQDLADRLGWGDDFE 261
YRDVA LG+CD+GC LA+ LGW + E
Sbjct: 278 YRDVAWLGECDQGCLALAELLGWKKELE 305
>AF083107-1|AAD40850.2| 389|Homo sapiens sirtuin type 2 protein.
Length = 389
Score = 98.3 bits (234), Expect = 3e-20
Identities = 48/88 (54%), Positives = 63/88 (71%), Gaps = 1/88 (1%)
Frame = +1
Query: 1 DMLIIMGSSLEVQPFASLIDMVPDSCPRLLINREKAGVRPPILRIRGLMCGGLQLD-EGS 177
D+L++MG+SL+VQPFASLI P S PRLLIN+EKAG P L + + GG+ D + +
Sbjct: 255 DLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAGQSDPFLGMIMGLGGGMDFDSKKA 314
Query: 178 YRDVARLGDCDEGCQDLADRLGWGDDFE 261
YRDVA LG+CD+GC LA+ LGW + E
Sbjct: 315 YRDVAWLGECDQGCLALAELLGWKKELE 342
>BC001042-1|AAH01042.1| 399|Homo sapiens sirtuin (silent mating
type information regulation 2 homolog) 3 (S. cerevisiae)
protein.
Length = 399
Score = 59.7 bits (138), Expect = 1e-08
Identities = 37/85 (43%), Positives = 49/85 (57%)
Frame = +1
Query: 1 DMLIIMGSSLEVQPFASLIDMVPDSCPRLLINREKAGVRPPILRIRGLMCGGLQLDEGSY 180
D+L+I+G+SLEV+PFASL + V S PRLLINR+ G P R
Sbjct: 313 DLLLILGTSLEVEPFASLTEAVRSSVPRLLINRDLVG--PLAWHPRS------------- 357
Query: 181 RDVARLGDCDEGCQDLADRLGWGDD 255
RDVA+LGD G + L + LGW ++
Sbjct: 358 RDVAQLGDVVHGVESLVELLGWTEE 382
>AL137276-1|CAB70674.1| 118|Homo sapiens hypothetical protein
protein.
Length = 118
Score = 59.7 bits (138), Expect = 1e-08
Identities = 37/85 (43%), Positives = 49/85 (57%)
Frame = +1
Query: 1 DMLIIMGSSLEVQPFASLIDMVPDSCPRLLINREKAGVRPPILRIRGLMCGGLQLDEGSY 180
D+L+I+G+SLEV+PFASL + V S PRLLINR+ G P R
Sbjct: 32 DLLLILGTSLEVEPFASLTEAVRSSVPRLLINRDLVG--PLAWHPRS------------- 76
Query: 181 RDVARLGDCDEGCQDLADRLGWGDD 255
RDVA+LGD G + L + LGW ++
Sbjct: 77 RDVAQLGDVVHGVESLVELLGWTEE 101
>AF083108-1|AAD40851.1| 399|Homo sapiens sirtuin type 3 protein.
Length = 399
Score = 59.7 bits (138), Expect = 1e-08
Identities = 37/85 (43%), Positives = 49/85 (57%)
Frame = +1
Query: 1 DMLIIMGSSLEVQPFASLIDMVPDSCPRLLINREKAGVRPPILRIRGLMCGGLQLDEGSY 180
D+L+I+G+SLEV+PFASL + V S PRLLINR+ G P R
Sbjct: 313 DLLLILGTSLEVEPFASLTEAVRSSVPRLLINRDLVG--PLAWHPRS------------- 357
Query: 181 RDVARLGDCDEGCQDLADRLGWGDD 255
RDVA+LGD G + L + LGW ++
Sbjct: 358 RDVAQLGDVVHGVESLVELLGWTEE 382
>DQ278604-1|ABB72675.1| 747|Homo sapiens sirtuin (silent mating
type information regulation 2 homolog) 1 (S. cerevisiae)
protein.
Length = 747
Score = 41.1 bits (92), Expect = 0.004
Identities = 29/81 (35%), Positives = 42/81 (51%)
Frame = +1
Query: 1 DMLIIMGSSLEVQPFASLIDMVPDSCPRLLINREKAGVRPPILRIRGLMCGGLQLDEGSY 180
D+LI++GSSL+V+P A + +P P++LINRE P+ + +
Sbjct: 434 DLLIVIGSSLKVRPVALIPSSIPHEVPQILINRE------PLPHL--------------H 473
Query: 181 RDVARLGDCDEGCQDLADRLG 243
DV LGDCD +L RLG
Sbjct: 474 FDVELLGDCDVIINELCHRLG 494
>BC012499-1|AAH12499.1| 555|Homo sapiens SIRT1 protein protein.
Length = 555
Score = 41.1 bits (92), Expect = 0.004
Identities = 29/81 (35%), Positives = 42/81 (51%)
Frame = +1
Query: 1 DMLIIMGSSLEVQPFASLIDMVPDSCPRLLINREKAGVRPPILRIRGLMCGGLQLDEGSY 180
D+LI++GSSL+V+P A + +P P++LINRE P+ + +
Sbjct: 242 DLLIVIGSSLKVRPVALIPSSIPHEVPQILINRE------PLPHL--------------H 281
Query: 181 RDVARLGDCDEGCQDLADRLG 243
DV LGDCD +L RLG
Sbjct: 282 FDVELLGDCDVIINELCHRLG 302
>AL133551-8|CAI16036.1| 747|Homo sapiens sirtuin (silent mating
type information regulation 2 homolog) 1 (S. cerevisiae)
protein.
Length = 747
Score = 41.1 bits (92), Expect = 0.004
Identities = 29/81 (35%), Positives = 42/81 (51%)
Frame = +1
Query: 1 DMLIIMGSSLEVQPFASLIDMVPDSCPRLLINREKAGVRPPILRIRGLMCGGLQLDEGSY 180
D+LI++GSSL+V+P A + +P P++LINRE P+ + +
Sbjct: 434 DLLIVIGSSLKVRPVALIPSSIPHEVPQILINRE------PLPHL--------------H 473
Query: 181 RDVARLGDCDEGCQDLADRLG 243
DV LGDCD +L RLG
Sbjct: 474 FDVELLGDCDVIINELCHRLG 494
>AF235040-1|AAG38486.1| 747|Homo sapiens SIR2alpha protein protein.
Length = 747
Score = 41.1 bits (92), Expect = 0.004
Identities = 29/81 (35%), Positives = 42/81 (51%)
Frame = +1
Query: 1 DMLIIMGSSLEVQPFASLIDMVPDSCPRLLINREKAGVRPPILRIRGLMCGGLQLDEGSY 180
D+LI++GSSL+V+P A + +P P++LINRE P+ + +
Sbjct: 434 DLLIVIGSSLKVRPVALIPSSIPHEVPQILINRE------PLPHL--------------H 473
Query: 181 RDVARLGDCDEGCQDLADRLG 243
DV LGDCD +L RLG
Sbjct: 474 FDVELLGDCDVIINELCHRLG 494
>AF083106-1|AAD40849.2| 747|Homo sapiens sirtuin type 1 protein.
Length = 747
Score = 41.1 bits (92), Expect = 0.004
Identities = 29/81 (35%), Positives = 42/81 (51%)
Frame = +1
Query: 1 DMLIIMGSSLEVQPFASLIDMVPDSCPRLLINREKAGVRPPILRIRGLMCGGLQLDEGSY 180
D+LI++GSSL+V+P A + +P P++LINRE P+ + +
Sbjct: 434 DLLIVIGSSLKVRPVALIPSSIPHEVPQILINRE------PLPHL--------------H 473
Query: 181 RDVARLGDCDEGCQDLADRLG 243
DV LGDCD +L RLG
Sbjct: 474 FDVELLGDCDVIINELCHRLG 494
>BC008744-1|AAH08744.2| 440|Homo sapiens PLEKHQ1 protein protein.
Length = 440
Score = 31.5 bits (68), Expect = 3.3
Identities = 26/78 (33%), Positives = 36/78 (46%)
Frame = -3
Query: 251 SPHPSLSAKSWQPSSQSPSLATSL*EPSSNCKPPHINPLILNIGGLTPAFSRFIRSRGHE 72
SP + +A+S +PS Q+P TS P KPP P IL+ L + S
Sbjct: 228 SPQEAPAAESAEPS-QAPCSETSEAAPREGGKPPTPPPKILS-EKLKASMGEMQASGPPA 285
Query: 71 SGTISISDANGCTSSEDP 18
GT+ +S NG S +P
Sbjct: 286 PGTVQVS-VNGMDDSPEP 302
>AF494534-1|AAM18053.1| 490|Homo sapiens PH domain containing
protein protein.
Length = 490
Score = 31.5 bits (68), Expect = 3.3
Identities = 26/78 (33%), Positives = 36/78 (46%)
Frame = -3
Query: 251 SPHPSLSAKSWQPSSQSPSLATSL*EPSSNCKPPHINPLILNIGGLTPAFSRFIRSRGHE 72
SP + +A+S +PS Q+P TS P KPP P IL+ L + S
Sbjct: 278 SPQEAPAAESAEPS-QAPCSETSEAAPREGGKPPTPPPKILS-EKLKASMGEMQASGPPA 335
Query: 71 SGTISISDANGCTSSEDP 18
GT+ +S NG S +P
Sbjct: 336 PGTVQVS-VNGMDDSPEP 352
>U88713-1|AAC51916.1| 700|Homo sapiens phosphodiesterase 4C
protein.
Length = 700
Score = 30.7 bits (66), Expect = 5.8
Identities = 16/39 (41%), Positives = 19/39 (48%)
Frame = -1
Query: 286 RSCSRATNARSHPPIPVCLPSPGSLHHNLLASPHLYRNL 170
RS A A PP P +P PGS + SP L+R L
Sbjct: 12 RSSLHAVLAMQGPPAPAPVPGPGSPRGSPRGSPGLFRKL 50
>BC039897-1|AAH39897.1| 596|Homo sapiens PTPN5 protein protein.
Length = 596
Score = 30.7 bits (66), Expect = 5.8
Identities = 12/28 (42%), Positives = 18/28 (64%), Gaps = 2/28 (7%)
Frame = -1
Query: 292 SKRSCSRATNARSHPP--IPVCLPSPGS 215
+ R R T+ R+HPP +P C P+PG+
Sbjct: 7 TSRDTRRHTHTRAHPPASLPACSPAPGA 34
>BC117319-1|AAI17320.1| 257|Homo sapiens TPRXL protein protein.
Length = 257
Score = 30.3 bits (65), Expect = 7.6
Identities = 24/78 (30%), Positives = 37/78 (47%)
Frame = -3
Query: 260 SKSSPHPSLSAKSWQPSSQSPSLATSL*EPSSNCKPPHINPLILNIGGLTPAFSRFIRSR 81
S SSP S S+ S PSS + S ++S PSS+ +P + +P+ S S
Sbjct: 88 STSSPSSSSSSSSSSPSSSNSSSSSSSSSPSSSSSSSSSSP---SSSSSSPSSSSSSSSS 144
Query: 80 GHESGTISISDANGCTSS 27
S + S S ++ +SS
Sbjct: 145 SPSSSSSSPSSSSSSSSS 162
>AB202103-3|BAE78626.1| 152|Homo sapiens chromosome 6 open reading
frame 16 protein.
Length = 152
Score = 30.3 bits (65), Expect = 7.6
Identities = 14/43 (32%), Positives = 22/43 (51%), Gaps = 1/43 (2%)
Frame = -3
Query: 263 CSKSSPHPSLSAKSWQPSSQSPSLATSL*EPSSN-CKPPHINP 138
C+ H + + P+ Q P L + +PSS +PPH+NP
Sbjct: 3 CTDQKSHSQRALSTQTPALQGPQLLNT--DPSSEETRPPHVNP 43
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 104,562,055
Number of Sequences: 237096
Number of extensions: 2201457
Number of successful extensions: 5049
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 4724
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5027
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8903143626
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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