Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= br--1517
(648 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q7QA69 Cluster: ENSANGP00000003764; n=2; Culicidae|Rep:... 101 2e-20
UniRef50_UPI00015B4767 Cluster: PREDICTED: similar to glutamate-... 100 6e-20
UniRef50_Q9VCW4 Cluster: CG4917-PB, isoform B; n=3; Drosophila m... 93 5e-18
UniRef50_UPI0000D56F37 Cluster: PREDICTED: similar to CG4917-PA,... 93 7e-18
UniRef50_UPI000065FC34 Cluster: Wolframin.; n=1; Takifugu rubrip... 42 0.010
UniRef50_UPI000054533D Cluster: PREDICTED: hypothetical protein;... 40 0.039
UniRef50_O76024 Cluster: Wolframin; n=26; Fungi/Metazoa group|Re... 40 0.069
UniRef50_A7SVB7 Cluster: Predicted protein; n=1; Nematostella ve... 39 0.091
UniRef50_O21278 Cluster: ABC transporter subunit C; n=1; Reclino... 35 1.5
UniRef50_A5FMW7 Cluster: Alpha-2-macroglobulin domain protein pr... 34 3.4
UniRef50_A0Z890 Cluster: Putative uncharacterized protein; n=1; ... 33 4.5
UniRef50_Q6ZRJ0 Cluster: CDNA FLJ46325 fis, clone TESTI4043371; ... 33 4.5
UniRef50_UPI0000E4884A Cluster: PREDICTED: similar to SPBPJ4664.... 33 6.0
UniRef50_A5CFS1 Cluster: Putative manganese transport system per... 33 6.0
>UniRef50_Q7QA69 Cluster: ENSANGP00000003764; n=2; Culicidae|Rep:
ENSANGP00000003764 - Anopheles gambiae str. PEST
Length = 852
Score = 101 bits (241), Expect = 2e-20
Identities = 49/89 (55%), Positives = 61/89 (68%), Gaps = 1/89 (1%)
Frame = +1
Query: 256 VRNNLGPFIQFFVALFVNLFLYPFIATQWVPFSELCVLSFFLMFLTLCSF-GANGNPYPD 432
+RNNL P+ FF A FVN+ L P I QW+PFSE+ VL+F L FLT+ +F +G+ +PD
Sbjct: 347 LRNNLKPYFYFFTAFFVNMVLQPNINDQWLPFSEITVLAFALTFLTMFAFIYTSGDSFPD 406
Query: 433 VLALISFAINVLAKYPYEKDTVVHQGGDF 519
L L SF +NVLAKYPYE D VV G F
Sbjct: 407 YLILFSFGLNVLAKYPYEMDDVVTTGWRF 435
Score = 74.1 bits (174), Expect = 3e-12
Identities = 33/73 (45%), Positives = 47/73 (64%)
Frame = +2
Query: 32 IELSLVLIAYLFVSADSXXXXXXXXXXXXSFVAMVICTFKMLHAKRQFIDFRKWSGLFLR 211
++L LVLI Y + ++D+ S MV+C+F+ML +K +FIDFR WSGLFLR
Sbjct: 272 MQLGLVLITYWYFASDNLVSLLPVGGYYLSLAIMVLCSFRMLKSKHEFIDFRMWSGLFLR 331
Query: 212 YSDGNLQPDESEN 250
Y D +L ++SEN
Sbjct: 332 YGDEHLNTNDSEN 344
Score = 57.2 bits (132), Expect = 3e-07
Identities = 23/49 (46%), Positives = 34/49 (69%)
Frame = +3
Query: 501 TSGWRFLDFHISNYPSYVLGNSIEFCLNGRMFFSXLIPVILVLMARRSD 647
T+GWRFLD + + ++V+GN IEFCLN R +IP L+ +ARR++
Sbjct: 430 TTGWRFLDLKVPGFSTFVIGNGIEFCLNCRAMLYLMIPGFLMYIARRNN 478
>UniRef50_UPI00015B4767 Cluster: PREDICTED: similar to
glutamate-cysteine ligase, regulatory-subunit, putative;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
glutamate-cysteine ligase, regulatory-subunit, putative
- Nasonia vitripennis
Length = 880
Score = 99.5 bits (237), Expect = 6e-20
Identities = 47/85 (55%), Positives = 59/85 (69%), Gaps = 2/85 (2%)
Frame = +1
Query: 259 RNNLGPFIQFFVALFVNLFLYPFIATQWVPFSELCVLSFFLMFLTLCSF--GANGNPYPD 432
RNNL P+ FF+AL +NL L+P +ATQW P SE V++F L +TL +F + YPD
Sbjct: 370 RNNLKPYAHFFLALLLNLMLFPIVATQWTPQSEFTVIAFALTLVTLLNFVWSETTSRYPD 429
Query: 433 VLALISFAINVLAKYPYEKDTVVHQ 507
LAL SF++NVLAKYPYE D VV Q
Sbjct: 430 FLALFSFSVNVLAKYPYEMDVVVAQ 454
Score = 58.0 bits (134), Expect = 2e-07
Identities = 24/46 (52%), Positives = 31/46 (67%)
Frame = +3
Query: 510 WRFLDFHISNYPSYVLGNSIEFCLNGRMFFSXLIPVILVLMARRSD 647
WRFLD + + SYV+GN IEFCLN R+ F LIP + + MA R +
Sbjct: 456 WRFLDIKVPTFASYVVGNGIEFCLNFRLVFYLLIPAVFLKMAARDN 501
Score = 56.0 bits (129), Expect = 7e-07
Identities = 26/77 (33%), Positives = 43/77 (55%)
Frame = +2
Query: 17 FRLSNIELSLVLIAYLFVSADSXXXXXXXXXXXXSFVAMVICTFKMLHAKRQFIDFRKWS 196
F +++ ++++ + + A+S SFV M I TF++L KR+ + R WS
Sbjct: 289 FFTTHLHAVILILLHALLGAESVVLFVPLALYYLSFVVMTIATFQILQRKRELSNLRVWS 348
Query: 197 GLFLRYSDGNLQPDESE 247
LFL YS G+L P+E+E
Sbjct: 349 RLFLSYSGGSLNPEEAE 365
>UniRef50_Q9VCW4 Cluster: CG4917-PB, isoform B; n=3; Drosophila
melanogaster|Rep: CG4917-PB, isoform B - Drosophila
melanogaster (Fruit fly)
Length = 872
Score = 93.1 bits (221), Expect = 5e-18
Identities = 41/83 (49%), Positives = 57/83 (68%), Gaps = 1/83 (1%)
Frame = +1
Query: 256 VRNNLGPFIQFFVALFVNLFLYPFIATQWVPFSELCVLSFFLMFLTLC-SFGANGNPYPD 432
+RNN+ P++ FF A NL +YP + W+P SEL ++S L F+T+C S A+ + PD
Sbjct: 358 LRNNMKPYLYFFCAFICNLIVYPLVTDAWLPHSELTIISGALTFITMCVSMYASSHQLPD 417
Query: 433 VLALISFAINVLAKYPYEKDTVV 501
L ++SFA+NVLAKYPYE D VV
Sbjct: 418 WLVIVSFAVNVLAKYPYEMDEVV 440
Score = 59.3 bits (137), Expect = 8e-08
Identities = 24/45 (53%), Positives = 32/45 (71%)
Frame = +3
Query: 510 WRFLDFHISNYPSYVLGNSIEFCLNGRMFFSXLIPVILVLMARRS 644
WRFLD + + S+V+GN IEFCLN R IPV+L++MA+RS
Sbjct: 444 WRFLDLRVPTFSSFVIGNGIEFCLNCRTALYLFIPVLLIMMAKRS 488
Score = 52.0 bits (119), Expect = 1e-05
Identities = 22/40 (55%), Positives = 29/40 (72%)
Frame = +2
Query: 131 MVICTFKMLHAKRQFIDFRKWSGLFLRYSDGNLQPDESEN 250
M+ T KML K+QF+DFR WSGLFL Y D N++ D +E+
Sbjct: 316 MIWATCKMLKTKQQFVDFRIWSGLFLSYGDQNIEADIAEH 355
>UniRef50_UPI0000D56F37 Cluster: PREDICTED: similar to CG4917-PA,
isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG4917-PA, isoform A - Tribolium castaneum
Length = 838
Score = 92.7 bits (220), Expect = 7e-18
Identities = 49/94 (52%), Positives = 58/94 (61%), Gaps = 3/94 (3%)
Frame = +1
Query: 247 EFV-VRNNLGPFIQFFVALFVNLFLYPFIATQWVPFSELCVLSFFLMFLTLCSF--GANG 417
EF+ VRNNL P+ FF +L +N +YP I QW+P SEL ++SF L F TL F G
Sbjct: 336 EFLYVRNNLKPYALFFGSLLLNFLVYPVIVDQWIPQSELMIISFCLTFATLLGFMYKRRG 395
Query: 418 NPYPDVLALISFAINVLAKYPYEKDTVVHQGGDF 519
D+L SF INVLAKYPYE D VV QG F
Sbjct: 396 KTVFDLLVFFSFGINVLAKYPYETDPVVAQGWRF 429
Score = 74.9 bits (176), Expect = 1e-12
Identities = 38/104 (36%), Positives = 60/104 (57%)
Frame = +2
Query: 11 FSFRLSNIELSLVLIAYLFVSADSXXXXXXXXXXXXSFVAMVICTFKMLHAKRQFIDFRK 190
F S ++L ++++ Y VSAD+ SF+AMVI TF+ML KR+F DFR
Sbjct: 258 FPLAKSEVQLLVLMVVYTLVSADNILYFFPLVLYYASFIAMVISTFQMLQIKREFHDFRL 317
Query: 191 WSGLFLRYSDGNLQPDESENLLYATIWVRSFSSLWRCL*IYFYI 322
WSGLF+ YS G+L +++E LY ++ ++ + L + F +
Sbjct: 318 WSGLFITYSGGDLNSEDAE-FLYVRNNLKPYALFFGSLLLNFLV 360
Score = 62.5 bits (145), Expect = 9e-09
Identities = 26/47 (55%), Positives = 33/47 (70%)
Frame = +3
Query: 507 GWRFLDFHISNYPSYVLGNSIEFCLNGRMFFSXLIPVILVLMARRSD 647
GWRFLD I + SYV+GN IEFC+N R+F IP++LV +A R D
Sbjct: 426 GWRFLDLKIPTFASYVIGNGIEFCINFRLFLYMFIPLLLVKIASRQD 472
>UniRef50_UPI000065FC34 Cluster: Wolframin.; n=1; Takifugu
rubripes|Rep: Wolframin. - Takifugu rubripes
Length = 793
Score = 42.3 bits (95), Expect = 0.010
Identities = 19/65 (29%), Positives = 32/65 (49%)
Frame = +1
Query: 262 NNLGPFIQFFVALFVNLFLYPFIATQWVPFSELCVLSFFLMFLTLCSFGANGNPYPDVLA 441
NNL P++ F +++F +F +P QW+P SEL ++ F ++ S Y
Sbjct: 348 NNLEPYLYFILSVFFVIFSFPVADKQWIPCSELSTVAIFFTAVSYNSLSHTATTYARRAI 407
Query: 442 LISFA 456
+I A
Sbjct: 408 IIEVA 412
>UniRef50_UPI000054533D Cluster: PREDICTED: hypothetical protein;
n=3; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 993
Score = 40.3 bits (90), Expect = 0.039
Identities = 19/70 (27%), Positives = 33/70 (47%)
Frame = +1
Query: 262 NNLGPFIQFFVALFVNLFLYPFIATQWVPFSELCVLSFFLMFLTLCSFGANGNPYPDVLA 441
NNL ++ F +++F +F +P W+P SEL ++ F L+ S + Y
Sbjct: 506 NNLEQYLYFMISVFFVIFTFPVADKGWIPCSELSTVAIFFTALSYMSLSPSAAAYARKAL 565
Query: 442 LISFAINVLA 471
I A ++ A
Sbjct: 566 FIEVASSLCA 575
>UniRef50_O76024 Cluster: Wolframin; n=26; Fungi/Metazoa group|Rep:
Wolframin - Homo sapiens (Human)
Length = 890
Score = 39.5 bits (88), Expect = 0.069
Identities = 16/55 (29%), Positives = 29/55 (52%)
Frame = +1
Query: 262 NNLGPFIQFFVALFVNLFLYPFIATQWVPFSELCVLSFFLMFLTLCSFGANGNPY 426
N+L P+ F +++F +F +P + +P SEL V++ F + S + PY
Sbjct: 400 NHLEPYAHFLLSVFFVIFSFPIASKDCIPCSELAVITGFFTVTSYLSLSTHAEPY 454
Score = 34.7 bits (76), Expect = 2.0
Identities = 16/43 (37%), Positives = 28/43 (65%)
Frame = +2
Query: 119 SFVAMVICTFKMLHAKRQFIDFRKWSGLFLRYSDGNLQPDESE 247
SF++MVICT K+ + + +FR + L LR+ + NL +++E
Sbjct: 353 SFISMVICTLKVFQDSKAWENFRTLTDLLLRF-EPNLDVEQAE 394
>UniRef50_A7SVB7 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 449
Score = 39.1 bits (87), Expect = 0.091
Identities = 20/68 (29%), Positives = 35/68 (51%)
Frame = +1
Query: 265 NLGPFIQFFVALFVNLFLYPFIATQWVPFSELCVLSFFLMFLTLCSFGANGNPYPDVLAL 444
++ P+I FF+ L + + ++P W+P SE LS +F T+ + + Y D A+
Sbjct: 116 SIRPYISFFICLLITVAVFPLCDKSWIPCSE---LSLVALFFTVSALRGLPSDYDD-YAM 171
Query: 445 ISFAINVL 468
+ I VL
Sbjct: 172 YTIGIKVL 179
>UniRef50_O21278 Cluster: ABC transporter subunit C; n=1;
Reclinomonas americana|Rep: ABC transporter subunit C -
Reclinomonas americana
Length = 262
Score = 35.1 bits (77), Expect = 1.5
Identities = 28/80 (35%), Positives = 40/80 (50%), Gaps = 6/80 (7%)
Frame = +1
Query: 289 FVALFV-NLFLYPFIATQWVPFSELC-VLSFFLMFLTLCSFGANGNP----YPDVLALIS 450
F LF +L+ YP T WV + L VL F ++L + SF N + +L +I
Sbjct: 120 FTTLFTGSLWGYPVWGTFWVWDARLTSVLVLFFIYLIIWSFFLNQDEKIYKIGCILTIIF 179
Query: 451 FAINVLAKYPYEKDTVVHQG 510
FAI + KY + T +HQG
Sbjct: 180 FAIIPIIKYSVDWWTTLHQG 199
>UniRef50_A5FMW7 Cluster: Alpha-2-macroglobulin domain protein
precursor; n=1; Flavobacterium johnsoniae UW101|Rep:
Alpha-2-macroglobulin domain protein precursor -
Flavobacterium johnsoniae UW101
Length = 2084
Score = 33.9 bits (74), Expect = 3.4
Identities = 19/46 (41%), Positives = 26/46 (56%), Gaps = 2/46 (4%)
Frame = -1
Query: 306 HKQRHKELNERTQIVAYNKFSDSSGCKLPSLYLKKRP--DHLRKSI 175
HK R K L E +++ YN +SD S YL+K P D L+K+I
Sbjct: 1694 HKTRTKNLKEVDKLIWYNPYSDLHYLYTRSFYLEKYPQSDTLKKTI 1739
>UniRef50_A0Z890 Cluster: Putative uncharacterized protein; n=1;
marine gamma proteobacterium HTCC2080|Rep: Putative
uncharacterized protein - marine gamma proteobacterium
HTCC2080
Length = 199
Score = 33.5 bits (73), Expect = 4.5
Identities = 13/39 (33%), Positives = 24/39 (61%)
Frame = +1
Query: 259 RNNLGPFIQFFVALFVNLFLYPFIATQWVPFSELCVLSF 375
+N + P + + + +++F F+ATQWV FS+ + SF
Sbjct: 62 KNRISPEFRRYAGILIDVFYDHFLATQWVSFSDQPLNSF 100
>UniRef50_Q6ZRJ0 Cluster: CDNA FLJ46325 fis, clone TESTI4043371;
n=1; Homo sapiens|Rep: CDNA FLJ46325 fis, clone
TESTI4043371 - Homo sapiens (Human)
Length = 161
Score = 33.5 bits (73), Expect = 4.5
Identities = 19/51 (37%), Positives = 30/51 (58%), Gaps = 3/51 (5%)
Frame = +1
Query: 274 PFIQFFVALFV--NLFLYPFIATQWVPFSELCVLSFFLMF-LTLCSFGANG 417
PF+ FF++ F + FL+ F+ + + F LSFFL F ++LC G +G
Sbjct: 86 PFLSFFLSFFFFPSFFLFSFLLSLFPSFFLSLSLSFFLFFRVSLCHPGWSG 136
>UniRef50_UPI0000E4884A Cluster: PREDICTED: similar to SPBPJ4664.02;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
similar to SPBPJ4664.02 - Strongylocentrotus purpuratus
Length = 7366
Score = 33.1 bits (72), Expect = 6.0
Identities = 18/61 (29%), Positives = 34/61 (55%), Gaps = 1/61 (1%)
Frame = -3
Query: 376 RRTTRRAQKTEPIVLL*RDIKINSQTTPQ-RTE*TDPDCCVQQILRLVWLQITVAVPQEE 200
R+T +R ++EP + ++ Q TP RT+ T+PD Q+LR++ + V +++
Sbjct: 905 RKTNQRPDRSEPRTVSIVKLQAPHQPTPDTRTKGTNPDLSWNQVLRMIQSETEEIVERKQ 964
Query: 199 T 197
T
Sbjct: 965 T 965
>UniRef50_A5CFS1 Cluster: Putative manganese transport system
permease protein; n=1; uncultured marine
microorganism|Rep: Putative manganese transport system
permease protein - uncultured marine microorganism
Length = 308
Score = 33.1 bits (72), Expect = 6.0
Identities = 16/37 (43%), Positives = 21/37 (56%)
Frame = +1
Query: 268 LGPFIQFFVALFVNLFLYPFIATQWVPFSELCVLSFF 378
LG IQF +ALFV++ L P +A W + L FF
Sbjct: 99 LGAVIQFLIALFVDIGLLPILAAVWA-YMALMTKEFF 134
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 624,017,927
Number of Sequences: 1657284
Number of extensions: 12301416
Number of successful extensions: 29020
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 28136
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 28977
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 48955894634
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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