Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= br--1391
(763 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q4SVB7 Cluster: Pyruvate kinase; n=1; Tetraodon nigrovi... 116 6e-25
UniRef50_UPI0000D5551D Cluster: PREDICTED: similar to Pyruvate k... 115 1e-24
UniRef50_P30613 Cluster: Pyruvate kinase isozymes R/L; n=167; Fu... 112 8e-24
UniRef50_Q27686 Cluster: Pyruvate kinase; n=16; Kinetoplastida|R... 98 2e-19
UniRef50_Q04668 Cluster: Pyruvate kinase; n=2; Leishmania brazil... 96 1e-18
UniRef50_Q7RVA8 Cluster: Pyruvate kinase; n=11; Ascomycota|Rep: ... 94 3e-18
UniRef50_P80885 Cluster: Pyruvate kinase; n=161; Bacteria|Rep: P... 93 5e-18
UniRef50_Q9M057 Cluster: Pyruvate kinase; n=11; Magnoliophyta|Re... 93 7e-18
UniRef50_Q9VD23 Cluster: Pyruvate kinase; n=5; Coelomata|Rep: Py... 92 2e-17
UniRef50_Q42806 Cluster: Pyruvate kinase, cytosolic isozyme; n=6... 91 3e-17
UniRef50_O44006 Cluster: Pyruvate kinase; n=10; cellular organis... 85 2e-15
UniRef50_P94685 Cluster: Pyruvate kinase; n=8; Chlamydiaceae|Rep... 85 2e-15
UniRef50_Q8EX62 Cluster: Pyruvate kinase; n=5; Bacteria|Rep: Pyr... 84 3e-15
UniRef50_Q9VQH0 Cluster: Pyruvate kinase; n=3; Sophophora|Rep: P... 83 1e-14
UniRef50_Q2TSW8 Cluster: Pyruvate kinase; n=4; stramenopiles|Rep... 82 2e-14
UniRef50_Q4U977 Cluster: Pyruvate kinase, putative; n=3; Piropla... 82 2e-14
UniRef50_Q22Z06 Cluster: Pyruvate kinase family protein; n=3; Ol... 81 2e-14
UniRef50_Q090R5 Cluster: Pyruvate kinase; n=1; Stigmatella auran... 80 7e-14
UniRef50_Q9VFG4 Cluster: Pyruvate kinase; n=3; Sophophora|Rep: P... 80 7e-14
UniRef50_P52489 Cluster: Pyruvate kinase 2; n=33; Dikarya|Rep: P... 78 3e-13
UniRef50_P77983 Cluster: Pyruvate kinase I; n=29; Bacteria|Rep: ... 77 4e-13
UniRef50_A5C814 Cluster: Pyruvate kinase; n=1; Vitis vinifera|Re... 77 5e-13
UniRef50_Q1Q4I4 Cluster: Strongly similar to pyruvate kinase; n=... 77 6e-13
UniRef50_Q1NTW3 Cluster: Pyruvate kinase; n=1; delta proteobacte... 77 6e-13
UniRef50_Q1FK29 Cluster: Pyruvate kinase; n=4; Clostridiales|Rep... 76 8e-13
UniRef50_A4E9R2 Cluster: Pyruvate kinase; n=1; Collinsella aerof... 76 8e-13
UniRef50_Q0W8N0 Cluster: Pyruvate kinase; n=7; cellular organism... 76 8e-13
UniRef50_Q6MLB5 Cluster: Pyruvate kinase; n=1; Bdellovibrio bact... 75 1e-12
UniRef50_Q1K4D5 Cluster: Pyruvate kinase; n=1; Desulfuromonas ac... 75 1e-12
UniRef50_Q6MAN9 Cluster: Pyruvate kinase; n=1; Candidatus Protoc... 75 3e-12
UniRef50_Q08SK3 Cluster: Pyruvate kinase; n=2; Cystobacterineae|... 75 3e-12
UniRef50_UPI0000DA20CA Cluster: PREDICTED: similar to Pyruvate k... 74 3e-12
UniRef50_Q3JCE7 Cluster: Pyruvate kinase; n=1; Nitrosococcus oce... 74 3e-12
UniRef50_Q8SQP0 Cluster: Pyruvate kinase; n=1; Encephalitozoon c... 74 3e-12
UniRef50_Q55863 Cluster: Pyruvate kinase 1; n=5; Cyanobacteria|R... 74 4e-12
UniRef50_Q56XD5 Cluster: Pyruvate kinase; n=14; Magnoliophyta|Re... 73 6e-12
UniRef50_UPI00015BD1E0 Cluster: UPI00015BD1E0 related cluster; n... 72 2e-11
UniRef50_Q1IHI1 Cluster: Pyruvate kinase; n=2; Bacteria|Rep: Pyr... 72 2e-11
UniRef50_Q40546 Cluster: Pyruvate kinase isozyme G, chloroplast ... 71 2e-11
UniRef50_A7CUA8 Cluster: Pyruvate kinase; n=1; Opitutaceae bacte... 71 4e-11
UniRef50_Q8YTZ8 Cluster: Pyruvate kinase; n=3; Nostocaceae|Rep: ... 70 5e-11
UniRef50_A7HIL5 Cluster: Pyruvate kinase; n=9; Bacteria|Rep: Pyr... 70 5e-11
UniRef50_Q8PYY4 Cluster: Pyruvate kinase; n=3; Methanosarcinacea... 70 5e-11
UniRef50_Q8F253 Cluster: Pyruvate kinase; n=4; Leptospira|Rep: P... 70 7e-11
UniRef50_Q40545 Cluster: Pyruvate kinase isozyme A, chloroplast ... 69 1e-10
UniRef50_Q9KUN0 Cluster: Pyruvate kinase; n=24; cellular organis... 69 1e-10
UniRef50_Q8TJ98 Cluster: Pyruvate kinase; n=2; Methanomicrobia|R... 69 1e-10
UniRef50_Q1AXJ8 Cluster: Pyruvate kinase; n=1; Rubrobacter xylan... 69 2e-10
UniRef50_Q9RR62 Cluster: Pyruvate kinase; n=5; Bacteria|Rep: Pyr... 68 2e-10
UniRef50_Q2S3S2 Cluster: Pyruvate kinase; n=1; Salinibacter rube... 68 2e-10
UniRef50_Q2IHE2 Cluster: Pyruvate kinase; n=1; Anaeromyxobacter ... 68 2e-10
UniRef50_Q7UF82 Cluster: Pyruvate kinase; n=1; Pirellula sp.|Rep... 67 4e-10
UniRef50_Q4YDL9 Cluster: Putative uncharacterized protein; n=1; ... 67 4e-10
UniRef50_Q2JLA2 Cluster: Pyruvate kinase; n=2; Synechococcus|Rep... 67 5e-10
UniRef50_A0L7K0 Cluster: Pyruvate kinase; n=1; Magnetococcus sp.... 66 7e-10
UniRef50_Q6YQT6 Cluster: Pyruvate kinase; n=6; Candidatus Phytop... 66 9e-10
UniRef50_A6Q7D7 Cluster: Pyruvate kinase; n=19; cellular organis... 66 9e-10
UniRef50_A3I0G9 Cluster: Pyruvate kinase; n=3; Flexibacteraceae|... 66 9e-10
UniRef50_Q5IX04 Cluster: Pyruvate kinase; n=1; Prototheca wicker... 66 9e-10
UniRef50_Q5C2V0 Cluster: Pyruvate kinase; n=1; Schistosoma japon... 66 9e-10
UniRef50_Q6KHW9 Cluster: Pyruvate kinase; n=3; Mycoplasma|Rep: P... 66 1e-09
UniRef50_Q46078 Cluster: Pyruvate kinase; n=19; Actinobacteria (... 65 2e-09
UniRef50_Q82XE9 Cluster: Pyruvate kinase family; n=130; Proteoba... 64 3e-09
UniRef50_Q6A9P1 Cluster: Pyruvate kinase; n=4; Actinomycetales|R... 64 3e-09
UniRef50_Q0C0E8 Cluster: Pyruvate kinase; n=1; Hyphomonas neptun... 64 3e-09
UniRef50_P19680 Cluster: Pyruvate kinase; n=1; Spiroplasma citri... 64 4e-09
UniRef50_A4MK73 Cluster: Pyruvate kinase; n=1; Petrotoga mobilis... 64 5e-09
UniRef50_Q44473 Cluster: Pyruvate kinase; n=4; Proteobacteria|Re... 63 6e-09
UniRef50_Q1IJ65 Cluster: Pyruvate kinase; n=6; Bacteria|Rep: Pyr... 63 8e-09
UniRef50_A6C474 Cluster: Pyruvate kinase; n=1; Planctomyces mari... 63 8e-09
UniRef50_P73534 Cluster: Pyruvate kinase 2; n=37; Bacteria|Rep: ... 63 8e-09
UniRef50_Q2TSW6 Cluster: Pyruvate kinase; n=1; Achlya bisexualis... 62 1e-08
UniRef50_Q5V4I8 Cluster: Pyruvate kinase; n=4; Halobacteriaceae|... 62 1e-08
UniRef50_Q56301 Cluster: Pyruvate kinase; n=5; Thermococcaceae|R... 62 1e-08
UniRef50_Q81N35 Cluster: Pyruvate kinase; n=11; Bacillus cereus ... 62 1e-08
UniRef50_A1BQT0 Cluster: Pyruvate kinase; n=2; Eukaryota|Rep: Py... 62 1e-08
UniRef50_Q747D6 Cluster: Pyruvate kinase; n=6; Desulfuromonadale... 62 2e-08
UniRef50_A6Q5W9 Cluster: Pyruvate kinase; n=2; Epsilonproteobact... 62 2e-08
UniRef50_Q2FMN4 Cluster: Pyruvate kinase; n=1; Methanospirillum ... 62 2e-08
UniRef50_UPI0000D56D72 Cluster: PREDICTED: similar to CG7070-PB,... 61 3e-08
UniRef50_Q6AII5 Cluster: Pyruvate kinase; n=1; Desulfotalea psyc... 61 3e-08
UniRef50_Q6F1U1 Cluster: Pyruvate kinase; n=10; Mollicutes|Rep: ... 61 3e-08
UniRef50_A7D456 Cluster: Pyruvate kinase; n=2; Halobacteriaceae|... 61 3e-08
UniRef50_Q2I6K6 Cluster: Pyruvate kinase; n=1; uncultured delta ... 60 4e-08
UniRef50_Q94KE3 Cluster: Pyruvate kinase; n=25; Magnoliophyta|Re... 60 4e-08
UniRef50_Q63P20 Cluster: Pyruvate kinase; n=74; Proteobacteria|R... 60 8e-08
UniRef50_Q2TSX0 Cluster: Pyruvate kinase; n=2; cellular organism... 60 8e-08
UniRef50_A6DH47 Cluster: Pyruvate kinase; n=1; Lentisphaera aran... 59 1e-07
UniRef50_Q9YEU2 Cluster: Pyruvate kinase; n=1; Aeropyrum pernix|... 59 1e-07
UniRef50_O06134 Cluster: Pyruvate kinase; n=29; Bacteria|Rep: Py... 59 1e-07
UniRef50_A0QNT2 Cluster: Pyruvate kinase; n=1; Mycobacterium sme... 58 2e-07
UniRef50_Q9WY51 Cluster: Pyruvate kinase; n=3; Thermotogaceae|Re... 58 2e-07
UniRef50_Q0AHE3 Cluster: Pyruvate kinase; n=2; Nitrosomonadaceae... 58 3e-07
UniRef50_A7CAK5 Cluster: Pyruvate kinase; n=3; Ralstonia pickett... 58 3e-07
UniRef50_A6FYT4 Cluster: Pyruvate kinase; n=1; Plesiocystis paci... 58 3e-07
UniRef50_A1WED1 Cluster: Pyruvate kinase; n=1; Verminephrobacter... 58 3e-07
UniRef50_Q1ZJ78 Cluster: Pyruvate kinase; n=1; Psychromonas sp. ... 57 4e-07
UniRef50_Q7P1G4 Cluster: Pyruvate kinase; n=4; Bacteria|Rep: Pyr... 56 7e-07
UniRef50_Q1MPC8 Cluster: Pyruvate kinase; n=4; Desulfovibrionace... 56 1e-06
UniRef50_A1IEN3 Cluster: Pyruvate kinase; n=1; Candidatus Desulf... 56 1e-06
UniRef50_A0L5K6 Cluster: Pyruvate kinase; n=5; Proteobacteria|Re... 56 1e-06
UniRef50_Q8IJ37 Cluster: Pyruvate kinase; n=7; Plasmodium|Rep: P... 56 1e-06
UniRef50_Q8ZNW0 Cluster: Pyruvate kinase II; n=173; Proteobacter... 56 1e-06
UniRef50_UPI0000DB6F59 Cluster: PREDICTED: similar to Pyruvate k... 56 1e-06
UniRef50_Q8G5M1 Cluster: Pyruvate kinase; n=23; Actinobacteridae... 56 1e-06
UniRef50_A6LH43 Cluster: Pyruvate kinase; n=2; Parabacteroides|R... 54 4e-06
UniRef50_A7QH42 Cluster: Chromosome chr3 scaffold_95, whole geno... 53 9e-06
UniRef50_Q9PF54 Cluster: Pyruvate kinase; n=11; Xanthomonadaceae... 52 2e-05
UniRef50_Q0PQH4 Cluster: Pyruvate kinase; n=1; Endoriftia persep... 52 2e-05
UniRef50_A4APL1 Cluster: Pyruvate kinase; n=15; Bacteroidetes|Re... 52 2e-05
UniRef50_P46614 Cluster: Pyruvate kinase; n=1; Candida albicans|... 52 2e-05
UniRef50_A2BLH1 Cluster: Pyruvate kinase; n=1; Hyperthermus buty... 51 3e-05
UniRef50_P78031 Cluster: Pyruvate kinase; n=6; Mycoplasma|Rep: P... 51 4e-05
UniRef50_O05118 Cluster: Pyruvate kinase; n=44; Proteobacteria|R... 51 4e-05
UniRef50_Q7QVW2 Cluster: Pyruvate kinase; n=1; Giardia lamblia A... 50 5e-05
UniRef50_Q6L281 Cluster: Pyruvate kinase; n=2; Thermoplasmatales... 50 5e-05
UniRef50_A3ZTM3 Cluster: Pyruvate kinase; n=1; Blastopirellula m... 50 8e-05
UniRef50_A3ALA5 Cluster: Pyruvate kinase; n=3; Oryza sativa|Rep:... 49 1e-04
UniRef50_A3DMY9 Cluster: Pyruvate kinase; n=1; Staphylothermus m... 49 1e-04
UniRef50_Q5ZZ75 Cluster: Pyruvate kinase II; n=4; Legionella pne... 48 2e-04
UniRef50_Q07637 Cluster: Pyruvate kinase; n=44; Streptococcaceae... 48 3e-04
UniRef50_A5JEK8 Cluster: Pyruvate kinase; n=1; Nosema bombycis|R... 46 8e-04
UniRef50_O51323 Cluster: Pyruvate kinase; n=5; cellular organism... 46 8e-04
UniRef50_Q64MR8 Cluster: Pyruvate kinase; n=6; Bacteroides|Rep: ... 46 0.001
UniRef50_UPI00006CE5D4 Cluster: pyruvate kinase family protein; ... 45 0.002
UniRef50_P32044 Cluster: Pyruvate kinase; n=2; Thermoplasma|Rep:... 45 0.002
UniRef50_A7APT5 Cluster: Pyruvate kinase family protein; n=1; Ba... 45 0.002
UniRef50_Q8EWX2 Cluster: Pyruvate kinase; n=1; Mycoplasma penetr... 44 0.003
UniRef50_A4ARB8 Cluster: Pyruvate kinase; n=1; Flavobacteriales ... 44 0.005
UniRef50_A6LTB0 Cluster: Pyruvate kinase; n=1; Clostridium beije... 43 0.010
UniRef50_Q8MR79 Cluster: Pyruvate kinase; n=3; Sophophora|Rep: P... 43 0.010
UniRef50_Q4N603 Cluster: Pyruvate kinase; n=2; Theileria|Rep: Py... 42 0.022
UniRef50_A4VPY3 Cluster: Pyruvate kinase; n=1; Pseudomonas stutz... 41 0.029
UniRef50_Q4IUP8 Cluster: Pyruvate kinase; n=1; Azotobacter vinel... 41 0.038
UniRef50_A1RX09 Cluster: Pyruvate kinase; n=1; Thermofilum pende... 40 0.051
UniRef50_Q2JJ60 Cluster: Pyruvate kinase; n=5; Bacteria|Rep: Pyr... 40 0.067
UniRef50_A1U5Q4 Cluster: Pyruvate kinase; n=2; Marinobacter aqua... 40 0.067
UniRef50_A7PC98 Cluster: Chromosome chr2 scaffold_11, whole geno... 40 0.067
UniRef50_A7QTW5 Cluster: Chromosome undetermined scaffold_171, w... 39 0.12
UniRef50_Q5KVI2 Cluster: Pyruvate kinase; n=2; Geobacillus|Rep: ... 38 0.36
UniRef50_A3PTF7 Cluster: Pyruvate kinase; n=5; Mycobacterium|Rep... 36 1.1
UniRef50_Q9PQV7 Cluster: Pyruvate kinase; n=1; Ureaplasma parvum... 36 1.4
UniRef50_Q7NJ33 Cluster: Pyruvate kinase; n=1; Gloeobacter viola... 36 1.4
UniRef50_Q9M3B6 Cluster: Pyruvate kinase; n=1; Arabidopsis thali... 36 1.4
UniRef50_Q21J20 Cluster: Cell surface receptor IPT/TIG; n=1; Sac... 35 1.9
UniRef50_Q22CT0 Cluster: Pyruvate kinase, barrel domain containi... 34 4.4
UniRef50_Q5V7K4 Cluster: Putative uncharacterized protein; n=1; ... 33 5.8
UniRef50_Q9V2V8 Cluster: Pyruvate kinase; n=1; Thermoproteus ten... 33 5.8
UniRef50_Q4T5N2 Cluster: Chromosome undetermined SCAF9187, whole... 33 7.7
UniRef50_Q1D9T1 Cluster: 6-phosphofructokinase; n=1; Myxococcus ... 33 7.7
UniRef50_Q3EBL2 Cluster: Uncharacterized protein At2g37440.1; n=... 33 7.7
UniRef50_A1Y027 Cluster: Putative uncharacterized protein; n=1; ... 33 7.7
UniRef50_A2R204 Cluster: Contig An13c0090, complete genome; n=1;... 33 7.7
>UniRef50_Q4SVB7 Cluster: Pyruvate kinase; n=1; Tetraodon
nigroviridis|Rep: Pyruvate kinase - Tetraodon
nigroviridis (Green puffer)
Length = 569
Score = 116 bits (279), Expect = 6e-25
Identities = 53/85 (62%), Positives = 70/85 (82%)
Frame = +3
Query: 258 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 437
R +GIICTIGPASR+V +L++M+++GMN+AR+NFSHG+HEYHAETI+N REA +S+
Sbjct: 41 RNTGIICTIGPASRSVGMLKEMIKSGMNIARLNFSHGTHEYHAETIKNVREACESFEPGS 100
Query: 438 GSPFSLAIALDTKGPEIRTGLLEGA 512
+ IALDTKGPEIRTGL+ G+
Sbjct: 101 IQYRPIGIALDTKGPEIRTGLIHGS 125
Score = 85.4 bits (202), Expect = 1e-15
Identities = 46/92 (50%), Positives = 60/92 (65%), Gaps = 8/92 (8%)
Frame = +2
Query: 512 GSAEVELKKGETIKLTSSD-YQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQS 688
G+AEVELKKG IK+T D Y EK + + +++DYKNIT VV G++I+IDDGLIS+ +
Sbjct: 126 GTAEVELKKGNVIKITLDDAYVEKCSEEILWLDYKNITKVVDVGSKIYIDDGLISLQVKE 185
Query: 689 V-------SADTLTCTIENGGMLGSGKASTCP 763
+ +D L C IENGG LGS K P
Sbjct: 186 IGNSSISSGSDYLMCEIENGGTLGSKKGVNLP 217
>UniRef50_UPI0000D5551D Cluster: PREDICTED: similar to Pyruvate
kinase (PK); n=1; Tribolium castaneum|Rep: PREDICTED:
similar to Pyruvate kinase (PK) - Tribolium castaneum
Length = 557
Score = 115 bits (276), Expect = 1e-24
Identities = 56/86 (65%), Positives = 65/86 (75%), Gaps = 1/86 (1%)
Frame = +2
Query: 509 GGSAEVELKKGETIKLTSSD-YQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQ 685
G +AEVELKKGE IKLT+ Y EKG++ IYVDY NI VV+PGNRIF+DDGLIS+IC
Sbjct: 134 GIAAEVELKKGEQIKLTTDKAYLEKGSSSVIYVDYDNIQKVVQPGNRIFLDDGLISLICT 193
Query: 686 SVSADTLTCTIENGGMLGSGKASTCP 763
SV LTC++ENGGMLGS K P
Sbjct: 194 SVQGSVLTCSVENGGMLGSCKNVNLP 219
Score = 109 bits (261), Expect = 1e-22
Identities = 46/85 (54%), Positives = 66/85 (77%)
Frame = +3
Query: 255 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 434
+RL+GIICT+GP++ +V LE+M+E GMN+AR+ SHG+ E H E I+N R A ++YS +
Sbjct: 49 VRLTGIICTLGPSTTDVETLERMIEAGMNIARLTLSHGTQEMHTELIQNVRTAVENYSKR 108
Query: 435 LGSPFSLAIALDTKGPEIRTGLLEG 509
LG + L++ALD KGPE+RTG +EG
Sbjct: 109 LGVMYPLSLALDIKGPEVRTGYMEG 133
>UniRef50_P30613 Cluster: Pyruvate kinase isozymes R/L; n=167;
Fungi/Metazoa group|Rep: Pyruvate kinase isozymes R/L -
Homo sapiens (Human)
Length = 574
Score = 112 bits (270), Expect = 8e-24
Identities = 56/90 (62%), Positives = 72/90 (80%), Gaps = 3/90 (3%)
Frame = +3
Query: 258 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 437
R + II TIGPASR+V L++M++ GMN+AR+NFSHGSHEYHAE+I N REA +S++
Sbjct: 86 RSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFA--- 142
Query: 438 GSPFS---LAIALDTKGPEIRTGLLEGAAQ 518
GSP S +AIALDTKGPEIRTG+L+G +
Sbjct: 143 GSPLSYRPVAIALDTKGPEIRTGILQGGPE 172
Score = 84.6 bits (200), Expect = 2e-15
Identities = 40/86 (46%), Positives = 56/86 (65%), Gaps = 1/86 (1%)
Frame = +2
Query: 509 GGSAEVELKKGETIKLTSSD-YQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQ 685
G +EVEL KG + +T ++ +GNA+T++VDY NI VV G RI+IDDGLIS++ Q
Sbjct: 170 GPESEVELVKGSQVLVTVDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQ 229
Query: 686 SVSADTLTCTIENGGMLGSGKASTCP 763
+ + L +ENGG+LGS K P
Sbjct: 230 KIGPEGLVTQVENGGVLGSRKGVNLP 255
>UniRef50_Q27686 Cluster: Pyruvate kinase; n=16; Kinetoplastida|Rep:
Pyruvate kinase - Leishmania mexicana
Length = 499
Score = 97.9 bits (233), Expect = 2e-19
Identities = 49/84 (58%), Positives = 65/84 (77%)
Frame = +3
Query: 258 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 437
R + IICTIGP++++V L+ ++++GM+VARMNFSHGSHEYH TI N R+A +A+L
Sbjct: 20 RAARIICTIGPSTQSVEALKGLIQSGMSVARMNFSHGSHEYHQTTINNVRQA----AAEL 75
Query: 438 GSPFSLAIALDTKGPEIRTGLLEG 509
G ++AIALDTKGPEIRTG G
Sbjct: 76 G--VNIAIALDTKGPEIRTGQFVG 97
Score = 63.3 bits (147), Expect = 6e-09
Identities = 32/87 (36%), Positives = 50/87 (57%), Gaps = 2/87 (2%)
Frame = +2
Query: 509 GGSAEVELKKGETIKLTSSD-YQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQ 685
GG A +E +G T +T+ + +KG D Y+DY+N++ VV+PGN I+IDDG++ + Q
Sbjct: 97 GGDAVME--RGATCYVTTDPAFADKGTKDKFYIDYQNLSKVVRPGNYIYIDDGILILQVQ 154
Query: 686 S-VSADTLTCTIENGGMLGSGKASTCP 763
S TL CT+ N + + P
Sbjct: 155 SHEDEQTLECTVTNSHTISDRRGVNLP 181
>UniRef50_Q04668 Cluster: Pyruvate kinase; n=2; Leishmania
braziliensis|Rep: Pyruvate kinase - Leishmania
braziliensis
Length = 91
Score = 95.9 bits (228), Expect = 1e-18
Identities = 48/82 (58%), Positives = 66/82 (80%), Gaps = 1/82 (1%)
Frame = +3
Query: 255 IRLSG-IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSA 431
+R +G I+CTIGP++++V L+ ++++GM+VARMNFSHGSHEYH TI N R+A +A
Sbjct: 16 LRTTGTIVCTIGPSTQSVEALKGLIKSGMSVARMNFSHGSHEYHQTTINNVRQA----AA 71
Query: 432 KLGSPFSLAIALDTKGPEIRTG 497
+LG ++AIALDTKGPEIRTG
Sbjct: 72 ELG--VNIAIALDTKGPEIRTG 91
>UniRef50_Q7RVA8 Cluster: Pyruvate kinase; n=11; Ascomycota|Rep:
Pyruvate kinase - Neurospora crassa
Length = 527
Score = 94.3 bits (224), Expect = 3e-18
Identities = 46/80 (57%), Positives = 57/80 (71%)
Frame = +3
Query: 258 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 437
R + IICTIGP + +V + K+ + G+NV RMNFSHGS+EYH I N R+AEK +
Sbjct: 32 RRTSIICTIGPKTNSVEAINKLRDAGLNVVRMNFSHGSYEYHQSVIDNARQAEKVHP--- 88
Query: 438 GSPFSLAIALDTKGPEIRTG 497
G P +AIALDTKGPEIRTG
Sbjct: 89 GRP--IAIALDTKGPEIRTG 106
Score = 53.2 bits (122), Expect = 7e-06
Identities = 24/83 (28%), Positives = 46/83 (55%), Gaps = 2/83 (2%)
Frame = +2
Query: 521 EVELKKGETIKLTSSD-YQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISI-ICQSVS 694
++ + G + +T+ + Y+++ + +YVDY NIT V+ PG I++DDG+++ + + V
Sbjct: 113 DIPISAGTILNITTDEKYKDECTIEHMYVDYVNITKVIAPGRIIYVDDGVLAFEVLEIVD 172
Query: 695 ADTLTCTIENGGMLGSGKASTCP 763
T+ N G + S K P
Sbjct: 173 DKTIKVKARNNGYISSRKGVNLP 195
>UniRef50_P80885 Cluster: Pyruvate kinase; n=161; Bacteria|Rep:
Pyruvate kinase - Bacillus subtilis
Length = 585
Score = 93.5 bits (222), Expect = 5e-18
Identities = 49/92 (53%), Positives = 65/92 (70%), Gaps = 1/92 (1%)
Frame = +3
Query: 255 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 434
+R + I+CTIGPAS ++ +L K+ME+GMNVAR+NFSHG E H I+N REA K K
Sbjct: 1 MRKTKIVCTIGPASESIEMLTKLMESGMNVARLNFSHGDFEEHGARIKNIREASK----K 56
Query: 435 LGSPFSLAIALDTKGPEIRTGLLE-GAAQLKS 527
LG ++ I LDTKGPEIRT +E G +L++
Sbjct: 57 LGK--NVGILLDTKGPEIRTHTMENGGIELET 86
Score = 37.1 bits (82), Expect = 0.47
Identities = 28/91 (30%), Positives = 45/91 (49%), Gaps = 2/91 (2%)
Frame = +2
Query: 497 TLGRGGSAEVELKKGETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISI 676
T+ GG +EL+ G+ + + S D + G D I V Y+ + + V+ G+ I +DDGLI +
Sbjct: 76 TMENGG---IELETGKEL-IISMD-EVVGTTDKISVTYEGLVHDVEQGSTILLDDGLIGL 130
Query: 677 ICQSVSA--DTLTCTIENGGMLGSGKASTCP 763
V A + + N G L + K P
Sbjct: 131 EVLDVDAAKREIKTKVLNNGTLKNKKGVNVP 161
>UniRef50_Q9M057 Cluster: Pyruvate kinase; n=11; Magnoliophyta|Rep:
Pyruvate kinase - Arabidopsis thaliana (Mouse-ear cress)
Length = 510
Score = 93.1 bits (221), Expect = 7e-18
Identities = 45/87 (51%), Positives = 59/87 (67%)
Frame = +3
Query: 270 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 449
IICT+GP SR+V ++EK+++ GMNVAR NFSHGSH YH ET+ N R A + +
Sbjct: 20 IICTLGPVSRSVEMIEKLLKAGMNVARFNFSHGSHSYHQETLDNLRTAMDN------TGI 73
Query: 450 SLAIALDTKGPEIRTGLLEGAAQLKSN 530
A+ LDTKGPEIRTG L+ ++ N
Sbjct: 74 LSAVMLDTKGPEIRTGFLKEGKPIQLN 100
Score = 48.8 bits (111), Expect = 1e-04
Identities = 28/82 (34%), Positives = 43/82 (52%), Gaps = 2/82 (2%)
Frame = +2
Query: 524 VELKKGETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSV--SA 697
++L +G+ I + S DY +G+++ I + YK + VKPG+ I DG IS+ S S
Sbjct: 97 IQLNQGQEITI-SIDYMIEGDSNVISMSYKKLAEDVKPGDVILCSDGTISLTVLSCDKSF 155
Query: 698 DTLTCTIENGGMLGSGKASTCP 763
+ C EN +LG K P
Sbjct: 156 GLVRCRCENSAILGERKNVNLP 177
>UniRef50_Q9VD23 Cluster: Pyruvate kinase; n=5; Coelomata|Rep:
Pyruvate kinase - Drosophila melanogaster (Fruit fly)
Length = 744
Score = 91.9 bits (218), Expect = 2e-17
Identities = 41/88 (46%), Positives = 56/88 (63%), Gaps = 1/88 (1%)
Frame = +2
Query: 503 GRGGSAEVELKKGETIKL-TSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISII 679
G AE+ELK G+ + L T + +K N D IYVDY+ + +VKPGNR+F+DDGLI++I
Sbjct: 58 GGNDRAEIELKTGDKVTLSTKKEMADKSNKDNIYVDYQRLPQLVKPGNRVFVDDGLIALI 117
Query: 680 CQSVSADTLTCTIENGGMLGSGKASTCP 763
+ D + C +ENGG LGS K P
Sbjct: 118 VKESKGDEVICQVENGGKLGSHKGINLP 145
Score = 80.6 bits (190), Expect = 4e-14
Identities = 38/58 (65%), Positives = 43/58 (74%)
Frame = +3
Query: 336 MNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEG 509
M V RMNFSHGSHEYH +TI+ R+A Y + G P +LAIALDTKGPEIRTG L G
Sbjct: 1 MRVVRMNFSHGSHEYHCQTIQAARKAIAMYVEQTGLPRTLAIALDTKGPEIRTGKLAG 58
>UniRef50_Q42806 Cluster: Pyruvate kinase, cytosolic isozyme; n=62;
Eukaryota|Rep: Pyruvate kinase, cytosolic isozyme -
Glycine max (Soybean)
Length = 511
Score = 91.1 bits (216), Expect = 3e-17
Identities = 42/79 (53%), Positives = 56/79 (70%)
Frame = +3
Query: 270 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 449
I+CT+GPASR+V + EK++ GMNVAR NFSHG+H+YH ET+ N + +A +
Sbjct: 25 IVCTLGPASRSVEMTEKLLRAGMNVARFNFSHGTHDYHQETLNNLK------TAMHNTGI 78
Query: 450 SLAIALDTKGPEIRTGLLE 506
A+ LDTKGPEIRTG L+
Sbjct: 79 LCAVMLDTKGPEIRTGFLK 97
Score = 54.0 bits (124), Expect = 4e-06
Identities = 29/82 (35%), Positives = 44/82 (53%), Gaps = 2/82 (2%)
Frame = +2
Query: 524 VELKKGETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSAD- 700
++LK+G+ + +T+ DY KG+ + I + YK + +KPGN I DG I++ S D
Sbjct: 102 IQLKEGQEVTITT-DYDIKGDPEMISMSYKKLPVHLKPGNTILCSDGTITLTVLSCDPDA 160
Query: 701 -TLTCTIENGGMLGSGKASTCP 763
T+ C EN LG K P
Sbjct: 161 GTVRCRCENTATLGERKNVNLP 182
>UniRef50_O44006 Cluster: Pyruvate kinase; n=10; cellular
organisms|Rep: Pyruvate kinase - Eimeria tenella
Length = 531
Score = 85.0 bits (201), Expect = 2e-15
Identities = 39/80 (48%), Positives = 55/80 (68%)
Frame = +3
Query: 270 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 449
I+CT+GP+ +V + ++++ GMNV R+NFSHG HE H ++N +EA K K
Sbjct: 60 IVCTMGPSCWDVDKMVQLIDAGMNVCRLNFSHGDHEAHGRVVKNLQEALKQRPGK----- 114
Query: 450 SLAIALDTKGPEIRTGLLEG 509
+A+ LDTKGPEIRTG+LEG
Sbjct: 115 RVALLLDTKGPEIRTGMLEG 134
Score = 50.0 bits (114), Expect = 6e-05
Identities = 26/84 (30%), Positives = 41/84 (48%)
Frame = +2
Query: 512 GSAEVELKKGETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSV 691
G +EL G+ +K+ + DY GN I Y+ + + VKPGN I I DG +S+
Sbjct: 134 GDKPIELHAGDMLKIVT-DYSFVGNKSCIACSYEKLPSSVKPGNTILIADGSLSVEVVEC 192
Query: 692 SADTLTCTIENGGMLGSGKASTCP 763
D + + N ++G+ K P
Sbjct: 193 GKDYVMTRVMNPAIIGNKKNMNLP 216
>UniRef50_P94685 Cluster: Pyruvate kinase; n=8; Chlamydiaceae|Rep:
Pyruvate kinase - Chlamydia trachomatis
Length = 485
Score = 84.6 bits (200), Expect = 2e-15
Identities = 43/91 (47%), Positives = 58/91 (63%)
Frame = +3
Query: 252 VIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSA 431
+I + IICTIGPA+ +LEK+++ GMNVAR+NFSHG+HE H TI +E +
Sbjct: 1 MIARTKIICTIGPATNTPEMLEKLLDAGMNVARLNFSHGTHESHGRTIAILKELREKRQV 60
Query: 432 KLGSPFSLAIALDTKGPEIRTGLLEGAAQLK 524
LAI LDTKGPEIR G +E +++
Sbjct: 61 ------PLAIMLDTKGPEIRLGQVESPIKVQ 85
>UniRef50_Q8EX62 Cluster: Pyruvate kinase; n=5; Bacteria|Rep:
Pyruvate kinase - Leptospira interrogans
Length = 486
Score = 84.2 bits (199), Expect = 3e-15
Identities = 42/85 (49%), Positives = 58/85 (68%)
Frame = +3
Query: 252 VIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSA 431
V R + IICTIGPA+ + +++ + E GMNVAR+N SHG+H++H IRN + K
Sbjct: 7 VFRKTKIICTIGPATSDKKMIQALAEAGMNVARLNMSHGNHDFHRSIIRNIKSLNKDV-- 64
Query: 432 KLGSPFSLAIALDTKGPEIRTGLLE 506
L +P +AI LDT+GPEIRTG L+
Sbjct: 65 -LKNP--IAILLDTQGPEIRTGDLQ 86
Score = 52.8 bits (121), Expect = 9e-06
Identities = 25/80 (31%), Positives = 46/80 (57%)
Frame = +2
Query: 524 VELKKGETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADT 703
++LK GET +E +++V+YK+I +K G+ + +D+GLI+++ + ++
Sbjct: 90 LDLKVGETFTFHIIPGEES-EEQSVFVNYKDIVKDLKVGDPVTVDNGLINLVVEEINDSA 148
Query: 704 LTCTIENGGMLGSGKASTCP 763
L C + +GG LGS K P
Sbjct: 149 LKCKVLDGGRLGSRKHINLP 168
>UniRef50_Q9VQH0 Cluster: Pyruvate kinase; n=3; Sophophora|Rep:
Pyruvate kinase - Drosophila melanogaster (Fruit fly)
Length = 554
Score = 82.6 bits (195), Expect = 1e-14
Identities = 41/90 (45%), Positives = 58/90 (64%)
Frame = +3
Query: 258 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 437
RL +I TI +SRN + M+ G+N+ R+NFSH SHE H++TI EA + +
Sbjct: 32 RLVSLIATISVSSRNADTIYTMIMRGVNIFRLNFSHESHEMHSKTIELINEALERIHKET 91
Query: 438 GSPFSLAIALDTKGPEIRTGLLEGAAQLKS 527
G ++AIA DT+GP+IRTGLL+G L+S
Sbjct: 92 GQIRTVAIAADTRGPQIRTGLLDGDVFLRS 121
Score = 67.7 bits (158), Expect = 3e-10
Identities = 30/75 (40%), Positives = 48/75 (64%), Gaps = 1/75 (1%)
Frame = +2
Query: 521 EVELKKGETIKLT-SSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSA 697
+V L+ G+ ++L+ + D +KGN + +YVDY NI N+ K G+R+FIDDG + + V
Sbjct: 116 DVFLRSGDNLRLSINRDLYDKGNKEAVYVDYPNIINLTKTGDRLFIDDGRLLLHILEVGV 175
Query: 698 DTLTCTIENGGMLGS 742
D L C + +GG L +
Sbjct: 176 DGLLCEVIHGGQLNN 190
>UniRef50_Q2TSW8 Cluster: Pyruvate kinase; n=4; stramenopiles|Rep:
Pyruvate kinase - Phaeodactylum tricornutum
Length = 543
Score = 81.8 bits (193), Expect = 2e-14
Identities = 43/90 (47%), Positives = 58/90 (64%), Gaps = 1/90 (1%)
Frame = +3
Query: 258 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 437
R + I+CTIGPA NV LE ++E+GMNVAR NFSHG H H + R+A ++
Sbjct: 31 RRTKIVCTIGPACWNVDQLEILIESGMNVARFNFSHGDHAGHGAVLERVRQAAQNKGR-- 88
Query: 438 GSPFSLAIALDTKGPEIRTGLL-EGAAQLK 524
++AI LDTKGPEIRTG GA++++
Sbjct: 89 ----NIAILLDTKGPEIRTGFFANGASKIE 114
Score = 52.8 bits (121), Expect = 9e-06
Identities = 28/86 (32%), Positives = 48/86 (55%), Gaps = 2/86 (2%)
Frame = +2
Query: 512 GSAEVELKKGETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDG--LISIICQ 685
G++++EL KGETI LT SDY+ KG+ + Y + V G +I + DG +++++
Sbjct: 109 GASKIELVKGETIVLT-SDYKFKGDQHKLACSYPALAQSVTQGQQILVADGSLVLTVLQT 167
Query: 686 SVSADTLTCTIENGGMLGSGKASTCP 763
+A ++C I+N +G K P
Sbjct: 168 DEAAGEVSCRIDNNASMGERKNMNLP 193
>UniRef50_Q4U977 Cluster: Pyruvate kinase, putative; n=3;
Piroplasmida|Rep: Pyruvate kinase, putative - Theileria
annulata
Length = 513
Score = 81.8 bits (193), Expect = 2e-14
Identities = 38/79 (48%), Positives = 54/79 (68%)
Frame = +3
Query: 270 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 449
I+CT+GPA NV + +M+++GMN+ R NFSHG+HE H +T+ +EA KS
Sbjct: 42 IVCTMGPACGNVETIIQMVKSGMNICRFNFSHGNHETHTKTLNLVKEALKSVPEA----- 96
Query: 450 SLAIALDTKGPEIRTGLLE 506
++ + LDTKGPEIRTG L+
Sbjct: 97 NIGLMLDTKGPEIRTGFLK 115
Score = 45.2 bits (102), Expect = 0.002
Identities = 26/80 (32%), Positives = 40/80 (50%)
Frame = +2
Query: 524 VELKKGETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADT 703
+ L++G T+K+T+ DY +G+ I YK + VK GN I I DG +S +V D
Sbjct: 120 ITLEEGSTLKITT-DYTIEGDETIISCSYKKLPQSVKVGNIILIADGSLSCEVLAVFDDY 178
Query: 704 LTCTIENGGMLGSGKASTCP 763
+ + N +G K P
Sbjct: 179 IEVKVLNNAKIGEYKNMNLP 198
>UniRef50_Q22Z06 Cluster: Pyruvate kinase family protein; n=3;
Oligohymenophorea|Rep: Pyruvate kinase family protein -
Tetrahymena thermophila SB210
Length = 505
Score = 81.4 bits (192), Expect = 2e-14
Identities = 41/83 (49%), Positives = 55/83 (66%)
Frame = +3
Query: 258 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 437
R + I+CTIGP+ + L +++E GMNVAR+NFSHG H H ET+R +EA K+
Sbjct: 22 RKTKIVCTIGPSCWDHDNLVQLLENGMNVARLNFSHGDHAGHGETVRRLKEAFKA----- 76
Query: 438 GSPFSLAIALDTKGPEIRTGLLE 506
A+ LDTKGPEIRTGL++
Sbjct: 77 RKNIQCALMLDTKGPEIRTGLVK 99
Score = 43.2 bits (97), Expect = 0.007
Identities = 20/80 (25%), Positives = 40/80 (50%)
Frame = +2
Query: 524 VELKKGETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADT 703
+ L G+ +++T+ DY G+ + YK++ VK G ++ I DG + I + + D+
Sbjct: 106 INLVAGQELEITT-DYSVLGDEKVLACSYKSLPKSVKVGGQVLIADGTLVCIVKEIKQDS 164
Query: 704 LTCTIENGGMLGSGKASTCP 763
+ ++N +G K P
Sbjct: 165 IIVNVQNTCSIGEKKNMNLP 184
>UniRef50_Q090R5 Cluster: Pyruvate kinase; n=1; Stigmatella
aurantiaca DW4/3-1|Rep: Pyruvate kinase - Stigmatella
aurantiaca DW4/3-1
Length = 515
Score = 79.8 bits (188), Expect = 7e-14
Identities = 44/92 (47%), Positives = 62/92 (67%), Gaps = 1/92 (1%)
Frame = +3
Query: 252 VIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSA 431
++R + I+CT+GPAS++ +LE ++E GM+VAR+NFSHGSHE HAE I R A S
Sbjct: 9 LMRRAKIVCTLGPASQSQDMLEALIEAGMDVARLNFSHGSHEQHAENIAKLRAA----SL 64
Query: 432 KLGSPFSLAIALDTKGPEIRTG-LLEGAAQLK 524
KL ++ I D +GP+IRTG + G+ LK
Sbjct: 65 KLRK--AVGILGDLQGPKIRTGRFITGSTVLK 94
Score = 46.8 bits (106), Expect = 6e-04
Identities = 27/88 (30%), Positives = 43/88 (48%), Gaps = 1/88 (1%)
Frame = +2
Query: 503 GRGGSAEVELKKGETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISI-I 679
GR + LK+G +T+ D KGN D + Y ++ V PG+RI +DDGL+ + +
Sbjct: 84 GRFITGSTVLKEGAIFSITT-DESVKGNDDIVSTTYAHLAADVNPGDRILLDDGLLELKV 142
Query: 680 CQSVSADTLTCTIENGGMLGSGKASTCP 763
++ L + GG L + K P
Sbjct: 143 LETDKKQLLRTQVVIGGTLKNNKGINLP 170
>UniRef50_Q9VFG4 Cluster: Pyruvate kinase; n=3; Sophophora|Rep:
Pyruvate kinase - Drosophila melanogaster (Fruit fly)
Length = 1010
Score = 79.8 bits (188), Expect = 7e-14
Identities = 38/76 (50%), Positives = 51/76 (67%)
Frame = +3
Query: 261 LSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLG 440
L+ IICTIGP+S VL ++ GM V R++FS G+H+ H + I+ R+A Y+ + G
Sbjct: 184 LTSIICTIGPSSSQPEVLLNLIHAGMKVVRLDFSDGTHDCHCQAIQAARKAIAMYAEETG 243
Query: 441 SPFSLAIALDTKGPEI 488
P SLAIALDTKGP I
Sbjct: 244 LPRSLAIALDTKGPVI 259
>UniRef50_P52489 Cluster: Pyruvate kinase 2; n=33; Dikarya|Rep:
Pyruvate kinase 2 - Saccharomyces cerevisiae (Baker's
yeast)
Length = 506
Score = 77.8 bits (183), Expect = 3e-13
Identities = 38/81 (46%), Positives = 54/81 (66%)
Frame = +3
Query: 255 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 434
+R + II TIGP + + + + + G+N+ R+NFSHGS+E+H I N ++E+ +
Sbjct: 20 LRRTSIIGTIGPKTNSCEAITALRKAGLNIIRLNFSHGSYEFHQSVIENAVKSEQQFP-- 77
Query: 435 LGSPFSLAIALDTKGPEIRTG 497
G P LAIALDTKGPEIRTG
Sbjct: 78 -GRP--LAIALDTKGPEIRTG 95
Score = 50.4 bits (115), Expect = 5e-05
Identities = 23/75 (30%), Positives = 37/75 (49%), Gaps = 1/75 (1%)
Frame = +2
Query: 542 ETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISI-ICQSVSADTLTCTI 718
+ I T + + N +Y+DY N+T V+ PG I++DDG++S + Q + L
Sbjct: 110 QMIFTTDASFANTSNDKIMYIDYANLTKVIVPGRFIYVDDGILSFKVLQIIDESNLRVQA 169
Query: 719 ENGGMLGSGKASTCP 763
N G + S K P
Sbjct: 170 VNSGYIASHKGVNLP 184
>UniRef50_P77983 Cluster: Pyruvate kinase I; n=29; Bacteria|Rep:
Pyruvate kinase I - Salmonella typhimurium
Length = 470
Score = 77.4 bits (182), Expect = 4e-13
Identities = 40/80 (50%), Positives = 52/80 (65%)
Frame = +3
Query: 270 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 449
I+CTIGP + + +L KM++ GMNV R+NFSHG + H + I+N R + +K G
Sbjct: 6 IVCTIGPKTESEEMLSKMLDAGMNVMRLNFSHGDYAEHGQRIQNLR----NVMSKTGK-- 59
Query: 450 SLAIALDTKGPEIRTGLLEG 509
AI LDTKGPEIRT LEG
Sbjct: 60 KAAILLDTKGPEIRTIKLEG 79
Score = 56.4 bits (130), Expect = 7e-07
Identities = 28/89 (31%), Positives = 45/89 (50%)
Frame = +2
Query: 497 TLGRGGSAEVELKKGETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISI 676
T+ G +V LK G+T T+ D GN + + V Y+ T+ + GN + +DDGLI +
Sbjct: 74 TIKLEGGNDVSLKAGQTFTFTT-DKSVVGNNEIVAVTYEGFTSDLSVGNTVLVDDGLIGM 132
Query: 677 ICQSVSADTLTCTIENGGMLGSGKASTCP 763
++ + + C + N G LG K P
Sbjct: 133 EVTAIEGNKVICKVLNNGDLGENKGVNLP 161
>UniRef50_A5C814 Cluster: Pyruvate kinase; n=1; Vitis vinifera|Rep:
Pyruvate kinase - Vitis vinifera (Grape)
Length = 621
Score = 77.0 bits (181), Expect = 5e-13
Identities = 39/89 (43%), Positives = 56/89 (62%)
Frame = +3
Query: 258 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 437
R + I+CTIGP++ + ++ K+ ETGMNVAR+N SHG H H +TI +E + K+
Sbjct: 166 RKTKIVCTIGPSTSSREMIWKLAETGMNVARLNMSHGDHASHKKTIDLVKEYNAQFEDKV 225
Query: 438 GSPFSLAIALDTKGPEIRTGLLEGAAQLK 524
+AI LDTKGPE+R+G + LK
Sbjct: 226 -----IAIMLDTKGPEVRSGDVPKPIMLK 249
>UniRef50_Q1Q4I4 Cluster: Strongly similar to pyruvate kinase; n=1;
Candidatus Kuenenia stuttgartiensis|Rep: Strongly
similar to pyruvate kinase - Candidatus Kuenenia
stuttgartiensis
Length = 472
Score = 76.6 bits (180), Expect = 6e-13
Identities = 43/92 (46%), Positives = 59/92 (64%), Gaps = 1/92 (1%)
Frame = +3
Query: 258 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 437
R + I+CTIGPAS + A++E+++ GMNVAR+NFSHG H E I + R + S KL
Sbjct: 5 RKTKIVCTIGPASNSPAMIEQLICAGMNVARLNFSHGELSQHKECISHIR----AISEKL 60
Query: 438 GSPFSLAIALDTKGPEIRTGLLEG-AAQLKSN 530
P +A+ D GP+IR G+L G A LK+N
Sbjct: 61 MQP--VAVLQDLSGPKIRIGMLSGDAVTLKTN 90
Score = 34.3 bits (75), Expect = 3.3
Identities = 22/80 (27%), Positives = 36/80 (45%)
Frame = +2
Query: 524 VELKKGETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADT 703
V LK +T LT+ + GN I ++Y ++ V G+ + + DG I +
Sbjct: 85 VTLKTNDTFTLTTRNIV--GNERVISINYSDLPMNVSIGDTLLLSDGEIEVEVIQKDDRN 142
Query: 704 LTCTIENGGMLGSGKASTCP 763
+ C + GG+L S K P
Sbjct: 143 IHCKVIVGGVLTSRKGINIP 162
>UniRef50_Q1NTW3 Cluster: Pyruvate kinase; n=1; delta
proteobacterium MLMS-1|Rep: Pyruvate kinase - delta
proteobacterium MLMS-1
Length = 493
Score = 76.6 bits (180), Expect = 6e-13
Identities = 39/89 (43%), Positives = 56/89 (62%)
Frame = +3
Query: 258 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 437
R + I+CTIGPA+ + + ++ E GMNVAR+N SHGS E+H I N + K Y+
Sbjct: 16 RRTKIVCTIGPATASFEAICRLAEQGMNVARLNMSHGSREWHRGVIGNIKRYNKKYAG-- 73
Query: 438 GSPFSLAIALDTKGPEIRTGLLEGAAQLK 524
SLA+ LDT+G EIR+G L+ +L+
Sbjct: 74 ----SLAVLLDTRGAEIRSGDLKQDLELR 98
>UniRef50_Q1FK29 Cluster: Pyruvate kinase; n=4; Clostridiales|Rep:
Pyruvate kinase - Clostridium phytofermentans ISDg
Length = 580
Score = 76.2 bits (179), Expect = 8e-13
Identities = 43/91 (47%), Positives = 56/91 (61%), Gaps = 1/91 (1%)
Frame = +3
Query: 255 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 434
+R + I+CT+GPA+ + AVL ++M GM+VAR NFSHG +E H R SA+
Sbjct: 1 MRKTKIVCTLGPATEDDAVLRQLMIEGMDVARFNFSHGDYEQHTRNYERIRR----LSAE 56
Query: 435 LGSPFSLAIALDTKGPEIRTGLLE-GAAQLK 524
L P +A LDTKGPEIR G E G +LK
Sbjct: 57 LKLP--IATLLDTKGPEIRIGTFENGKIELK 85
Score = 60.1 bits (139), Expect = 6e-08
Identities = 29/88 (32%), Positives = 50/88 (56%)
Frame = +2
Query: 500 LGRGGSAEVELKKGETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISII 679
+G + ++ELKKG+ LT++D G+ + + YKN+ +K G +I IDDGLI +
Sbjct: 74 IGTFENGKIELKKGQIFTLTTNDIV--GDETQVSITYKNLIRDIKNGVKILIDDGLIELK 131
Query: 680 CQSVSADTLTCTIENGGMLGSGKASTCP 763
+++ + C + NGGM+ + K P
Sbjct: 132 VFNITDTDIICEVLNGGMISNHKGVNVP 159
>UniRef50_A4E9R2 Cluster: Pyruvate kinase; n=1; Collinsella
aerofaciens ATCC 25986|Rep: Pyruvate kinase -
Collinsella aerofaciens ATCC 25986
Length = 486
Score = 76.2 bits (179), Expect = 8e-13
Identities = 39/78 (50%), Positives = 51/78 (65%)
Frame = +3
Query: 270 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 449
I+CT+GPA + + +M++ GMNVAR NFSHGS++ H I R K +LG P
Sbjct: 7 IVCTMGPACDSDETIREMIKAGMNVARFNFSHGSYDEHHGRIERVRRISK----ELGLP- 61
Query: 450 SLAIALDTKGPEIRTGLL 503
+ I LDTKGPE+RTGLL
Sbjct: 62 -VGILLDTKGPEVRTGLL 78
Score = 57.6 bits (133), Expect = 3e-07
Identities = 28/83 (33%), Positives = 48/83 (57%), Gaps = 2/83 (2%)
Frame = +2
Query: 521 EVELKKGETIKLTSSDYQEK--GNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVS 694
+V +K G+ I +T+ E G A+ I +DY + + V+ G+ I IDDGL+++ +SV
Sbjct: 83 KVAVKTGDKIVVTAQPTSEDFHGTAEHISLDYLALPSEVEKGSLILIDDGLVALEVESVD 142
Query: 695 ADTLTCTIENGGMLGSGKASTCP 763
+TC ++N G++G K P
Sbjct: 143 GQDMTCVVKNDGLIGERKGVNMP 165
>UniRef50_Q0W8N0 Cluster: Pyruvate kinase; n=7; cellular
organisms|Rep: Pyruvate kinase - Uncultured methanogenic
archaeon RC-I
Length = 583
Score = 76.2 bits (179), Expect = 8e-13
Identities = 40/90 (44%), Positives = 55/90 (61%)
Frame = +3
Query: 255 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 434
+R + I+CTIGPA + +LEK+ GMNVAR+N SH HE+ +TI N R S
Sbjct: 1 MRKTKIVCTIGPACDSQDMLEKLAVAGMNVARLNMSHADHEHTVQTINNIR----MVSEA 56
Query: 435 LGSPFSLAIALDTKGPEIRTGLLEGAAQLK 524
+G P + I +D +GP+IR G L+ A LK
Sbjct: 57 IGKP--IGILMDLQGPKIRVGTLQQPANLK 84
Score = 42.7 bits (96), Expect = 0.010
Identities = 24/78 (30%), Positives = 37/78 (47%)
Frame = +2
Query: 530 LKKGETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLT 709
LK G T LT+ D G++ + V +K + V G + +DDGLI + +V+ +
Sbjct: 83 LKPGGTFTLTTRDVP--GDSQEVNVPFKELPQSVSTGQTLLLDDGLIELKVDAVTETDIR 140
Query: 710 CTIENGGMLGSGKASTCP 763
+ GG L S K P
Sbjct: 141 TKVVRGGELKSKKGINLP 158
>UniRef50_Q6MLB5 Cluster: Pyruvate kinase; n=1; Bdellovibrio
bacteriovorus|Rep: Pyruvate kinase - Bdellovibrio
bacteriovorus
Length = 495
Score = 75.4 bits (177), Expect = 1e-12
Identities = 40/90 (44%), Positives = 57/90 (63%), Gaps = 1/90 (1%)
Frame = +3
Query: 258 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 437
R + I+ TIGPA+R+ LEK ++ GMNVAR+NFSHGSHE H + + + R+ K A
Sbjct: 5 RRAKIVATIGPATRDEKNLEKAIKAGMNVARLNFSHGSHEDHLKVVHSLRKLSKELQA-- 62
Query: 438 GSPFSLAIALDTKGPEIRTGLLE-GAAQLK 524
+AI D +GP+IR G E G+ ++K
Sbjct: 63 ----PVAILQDLQGPKIRVGKFENGSIEIK 88
Score = 42.7 bits (96), Expect = 0.010
Identities = 22/88 (25%), Positives = 43/88 (48%)
Frame = +2
Query: 500 LGRGGSAEVELKKGETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISII 679
+G+ + +E+K GE + +T++ + G + D++ + PG RI +DDGL+ +
Sbjct: 77 VGKFENGSIEIKPGEKLVVTTA--KVLGKPGLVPSDFQELPLACVPGTRILLDDGLMEVK 134
Query: 680 CQSVSADTLTCTIENGGMLGSGKASTCP 763
V + + + GG+L K P
Sbjct: 135 VLQVRGEEIDVEVVYGGILKDRKGMNLP 162
>UniRef50_Q1K4D5 Cluster: Pyruvate kinase; n=1; Desulfuromonas
acetoxidans DSM 684|Rep: Pyruvate kinase -
Desulfuromonas acetoxidans DSM 684
Length = 474
Score = 75.4 bits (177), Expect = 1e-12
Identities = 39/83 (46%), Positives = 53/83 (63%)
Frame = +3
Query: 255 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 434
+R + I+CT+GPAS + A LE+M+ +GMNVAR+NFSHG H+ H + I R K +
Sbjct: 1 MRRTKIVCTVGPASADEATLEQMISSGMNVARLNFSHGDHDSHQQLIERIRAVAK----R 56
Query: 435 LGSPFSLAIALDTKGPEIRTGLL 503
L P +AI D GP+IR G L
Sbjct: 57 LNQP--VAILQDLCGPKIRLGQL 77
Score = 43.2 bits (97), Expect = 0.007
Identities = 24/88 (27%), Positives = 46/88 (52%)
Frame = +2
Query: 500 LGRGGSAEVELKKGETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISII 679
LG+ V L +G+ + L S+ +G+ + VDY ++ V+ G+ I + DGL+ +
Sbjct: 74 LGQLPEQGVRLHQGDAVSLCSTGQAGEGD---LPVDYPSLHEDVQVGDSIMLSDGLMELQ 130
Query: 680 CQSVSADTLTCTIENGGMLGSGKASTCP 763
+ + A + C++ +GG+ S K P
Sbjct: 131 VERIDAPQVQCSVISGGVAYSRKGVNMP 158
>UniRef50_Q6MAN9 Cluster: Pyruvate kinase; n=1; Candidatus
Protochlamydia amoebophila UWE25|Rep: Pyruvate kinase -
Protochlamydia amoebophila (strain UWE25)
Length = 598
Score = 74.5 bits (175), Expect = 3e-12
Identities = 39/76 (51%), Positives = 50/76 (65%)
Frame = +3
Query: 270 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 449
I+CTIGPA ++ + +++ GMNVAR+NFSHG+ E H TI +EA +L P
Sbjct: 8 IVCTIGPACNSLEKIIELINVGMNVARLNFSHGTQEEHLRTINLLKEAR----CQLNLP- 62
Query: 450 SLAIALDTKGPEIRTG 497
LAI LDTKGPEIR G
Sbjct: 63 -LAIMLDTKGPEIRLG 77
>UniRef50_Q08SK3 Cluster: Pyruvate kinase; n=2;
Cystobacterineae|Rep: Pyruvate kinase - Stigmatella
aurantiaca DW4/3-1
Length = 481
Score = 74.5 bits (175), Expect = 3e-12
Identities = 41/89 (46%), Positives = 54/89 (60%)
Frame = +3
Query: 255 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 434
+R + IICT+GPAS V+E ++ GMNVAR+NFSHG +E H + R+ S K
Sbjct: 16 MRKAKIICTLGPASDTPEVIEGLVRAGMNVARINFSHGVYEDHRRRVNTLRKV----SRK 71
Query: 435 LGSPFSLAIALDTKGPEIRTGLLEGAAQL 521
LG P +AI D +GP+IR G EG L
Sbjct: 72 LGIP--VAILQDIQGPKIRLGRFEGGQLL 98
Score = 40.7 bits (91), Expect = 0.038
Identities = 24/88 (27%), Positives = 44/88 (50%)
Frame = +2
Query: 500 LGRGGSAEVELKKGETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISII 679
LGR ++ ++ G+T+ +T+ +G I +++T V G+ I +DDG + +
Sbjct: 89 LGRFEGGQLLVQAGQTVTVTTRAVLGQGTL--IPTPVRSLTRDVTRGDMILLDDGRVRLR 146
Query: 680 CQSVSADTLTCTIENGGMLGSGKASTCP 763
V+ +T T+E GG+L K P
Sbjct: 147 VVRVAGRDVTATVEVGGLLKDHKGLNLP 174
>UniRef50_UPI0000DA20CA Cluster: PREDICTED: similar to Pyruvate
kinase isozyme M2; n=4; Rattus norvegicus|Rep:
PREDICTED: similar to Pyruvate kinase isozyme M2 -
Rattus norvegicus
Length = 123
Score = 74.1 bits (174), Expect = 3e-12
Identities = 36/71 (50%), Positives = 52/71 (73%)
Frame = +3
Query: 264 SGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGS 443
+GIICTIG ++V +L+ M+ +GMNVA +NFSHG+HEYHAETI+N +S+++
Sbjct: 45 TGIICTIG---QSVEMLKGMIMSGMNVAHLNFSHGTHEYHAETIKNVCATTESFASDPIL 101
Query: 444 PFSLAIALDTK 476
S+ +ALDTK
Sbjct: 102 YLSIVVALDTK 112
>UniRef50_Q3JCE7 Cluster: Pyruvate kinase; n=1; Nitrosococcus oceani
ATCC 19707|Rep: Pyruvate kinase - Nitrosococcus oceani
(strain ATCC 19707 / NCIMB 11848)
Length = 492
Score = 74.1 bits (174), Expect = 3e-12
Identities = 39/83 (46%), Positives = 54/83 (65%)
Frame = +3
Query: 258 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 437
R I+CTIGPASR+ A+L KM+ +GMNVAR+NFSHG+HE H REA + +L
Sbjct: 24 RACRIVCTIGPASRSPAILRKMLLSGMNVARLNFSHGNHESHGRIACEIREA----AQRL 79
Query: 438 GSPFSLAIALDTKGPEIRTGLLE 506
P +AI D +G ++R G ++
Sbjct: 80 MKP--VAILQDLQGHKVRVGKVQ 100
Score = 45.2 bits (102), Expect = 0.002
Identities = 25/80 (31%), Positives = 42/80 (52%)
Frame = +2
Query: 524 VELKKGETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADT 703
+ L++G+ I L + E ++ I +DY++I V PG ++F+DD I + S+
Sbjct: 105 LSLEEGQEILL---GHGETISSKRIGIDYQDIIQYVTPGQKVFLDDASIELEVLSIEEKD 161
Query: 704 LTCTIENGGMLGSGKASTCP 763
L C ++ GG L S K P
Sbjct: 162 LHCQVKFGGQLRSRKGVIFP 181
>UniRef50_Q8SQP0 Cluster: Pyruvate kinase; n=1; Encephalitozoon
cuniculi|Rep: Pyruvate kinase - Encephalitozoon cuniculi
Length = 519
Score = 74.1 bits (174), Expect = 3e-12
Identities = 34/77 (44%), Positives = 55/77 (71%)
Frame = +3
Query: 261 LSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLG 440
L+ I+CTIGP + + ++++++ GM++AR+NFSHGS E H E IRN R+ ++ G
Sbjct: 96 LTKIVCTIGPRTSSREKIKELIDAGMSIARLNFSHGSREAHLEVIRNIRD------SRSG 149
Query: 441 SPFSLAIALDTKGPEIR 491
+ ++IALDT+GPE+R
Sbjct: 150 AGRHVSIALDTRGPEVR 166
Score = 39.1 bits (87), Expect = 0.12
Identities = 17/41 (41%), Positives = 23/41 (56%)
Frame = +2
Query: 641 NRIFIDDGLISIICQSVSADTLTCTIENGGMLGSGKASTCP 763
NR+FIDDG I + +V D C + N GM+ S K+ P
Sbjct: 208 NRVFIDDGAIELRVVNVEEDGFECEVLNSGMIKSNKSMNFP 248
>UniRef50_Q55863 Cluster: Pyruvate kinase 1; n=5; Cyanobacteria|Rep:
Pyruvate kinase 1 - Synechocystis sp. (strain PCC 6803)
Length = 483
Score = 73.7 bits (173), Expect = 4e-12
Identities = 38/80 (47%), Positives = 54/80 (67%)
Frame = +3
Query: 270 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 449
I+ TIGPAS +V V+ +M++ GMNVAR+NFSHGS+E HA +R R E+ ++ +P
Sbjct: 20 IVATIGPASSSVEVIRQMVDAGMNVARLNFSHGSYEDHATMVRLLRSVEQ----EMDTPI 75
Query: 450 SLAIALDTKGPEIRTGLLEG 509
+L D +GP+IR G L G
Sbjct: 76 TL--LQDLQGPKIRIGQLPG 93
Score = 49.6 bits (113), Expect = 8e-05
Identities = 24/88 (27%), Positives = 45/88 (51%)
Frame = +2
Query: 500 LGRGGSAEVELKKGETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISII 679
+G+ E +L++GE + L + ++ + + +DY ++ K G RI +DDGL+ +
Sbjct: 88 IGQLPGGEKQLREGEKVSLVPVEIGDR-HPGAVGIDYPHLATEAKVGERILLDDGLLEMK 146
Query: 680 CQSVSADTLTCTIENGGMLGSGKASTCP 763
S+ + C + GG+L S K P
Sbjct: 147 VVSIQDPEVICEVVTGGILKSRKGVNLP 174
>UniRef50_Q56XD5 Cluster: Pyruvate kinase; n=14; Magnoliophyta|Rep:
Pyruvate kinase - Arabidopsis thaliana (Mouse-ear cress)
Length = 579
Score = 73.3 bits (172), Expect = 6e-12
Identities = 37/82 (45%), Positives = 53/82 (64%)
Frame = +3
Query: 252 VIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSA 431
V R + I+CT+GP++ ++ K+ E GMNVARMN SHG H H + I + K Y+A
Sbjct: 108 VRRKTKIVCTVGPSTNTREMIWKLAEAGMNVARMNMSHGDHASHKKVI----DLVKEYNA 163
Query: 432 KLGSPFSLAIALDTKGPEIRTG 497
+ ++AI LDTKGPE+R+G
Sbjct: 164 QT-KDNTIAIMLDTKGPEVRSG 184
>UniRef50_UPI00015BD1E0 Cluster: UPI00015BD1E0 related cluster; n=1;
unknown|Rep: UPI00015BD1E0 UniRef100 entry - unknown
Length = 477
Score = 71.7 bits (168), Expect = 2e-11
Identities = 36/76 (47%), Positives = 46/76 (60%)
Frame = +3
Query: 270 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 449
I+CTIGPAS+ V L KM+E GMN+AR+NF+HGS E H + N R+A K
Sbjct: 11 IVCTIGPASQEVETLTKMIENGMNIARINFAHGSFEEHETVVENIRKASKIVGK------ 64
Query: 450 SLAIALDTKGPEIRTG 497
+ I D GP+IR G
Sbjct: 65 DVTIMGDLPGPKIRIG 80
>UniRef50_Q1IHI1 Cluster: Pyruvate kinase; n=2; Bacteria|Rep:
Pyruvate kinase - Acidobacteria bacterium (strain
Ellin345)
Length = 509
Score = 71.7 bits (168), Expect = 2e-11
Identities = 35/83 (42%), Positives = 51/83 (61%)
Frame = +3
Query: 258 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 437
R + I+CTIGPA A ++++M GM+VAR+NFSHG+H+ H I+ R+
Sbjct: 20 RRAKIVCTIGPACNTEAAMQELMRAGMDVARLNFSHGTHDEHLVVIQRLRKVAAEEQR-- 77
Query: 438 GSPFSLAIALDTKGPEIRTGLLE 506
S+ I D +GP+IRTGLL+
Sbjct: 78 ----SICILQDLQGPKIRTGLLK 96
Score = 42.3 bits (95), Expect = 0.013
Identities = 23/80 (28%), Positives = 38/80 (47%)
Frame = +2
Query: 524 VELKKGETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADT 703
V L+ G T+ +T D G+A + ++ + V+PG+RI + DG I + +
Sbjct: 101 VMLETGNTVTITPRDIV--GDASLLATTFQTLALDVQPGSRILLSDGKIELSVSRIEGAD 158
Query: 704 LTCTIENGGMLGSGKASTCP 763
+ C I NGG L + P
Sbjct: 159 VECHIVNGGELKEHQGINIP 178
>UniRef50_Q40546 Cluster: Pyruvate kinase isozyme G, chloroplast
precursor; n=58; Viridiplantae|Rep: Pyruvate kinase
isozyme G, chloroplast precursor - Nicotiana tabacum
(Common tobacco)
Length = 562
Score = 71.3 bits (167), Expect = 2e-11
Identities = 37/98 (37%), Positives = 57/98 (58%)
Frame = +3
Query: 204 LPAPAYVRSRH*LQVFVIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYH 383
+P+ Y + + + R + I+CTIGP++ + ++ K+ E GMNVAR+N SHG H H
Sbjct: 73 VPSSGYSLGQESVYLNSPRKTKIVCTIGPSTSSREMIWKLAEAGMNVARLNMSHGDHASH 132
Query: 384 AETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTG 497
TI +E + K+ +AI LDTKGPE+ +G
Sbjct: 133 QRTIDLVKEYNAQFEDKV-----IAIMLDTKGPEVISG 165
Score = 41.5 bits (93), Expect = 0.022
Identities = 21/65 (32%), Positives = 39/65 (60%), Gaps = 7/65 (10%)
Frame = +2
Query: 590 DTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGS-------GK 748
DT+ V+Y + N V+ G+ + +D G++S+ +S ++D + C + +GG L S GK
Sbjct: 191 DTVSVNYDDFINDVEAGDILLVDGGMMSLAVKSKTSDIVKCEVIDGGELKSRRHLNVRGK 250
Query: 749 ASTCP 763
++T P
Sbjct: 251 SATLP 255
>UniRef50_A7CUA8 Cluster: Pyruvate kinase; n=1; Opitutaceae
bacterium TAV2|Rep: Pyruvate kinase - Opitutaceae
bacterium TAV2
Length = 480
Score = 70.5 bits (165), Expect = 4e-11
Identities = 37/91 (40%), Positives = 57/91 (62%)
Frame = +3
Query: 255 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 434
IR + I+ T+GPA+ + +LEK++ G +VAR+N +H +HE+ IR RE K +
Sbjct: 10 IRRTKIVFTLGPATESEEMLEKLIRAGADVARLNMAHANHEWTRMIIRRIREVSK----R 65
Query: 435 LGSPFSLAIALDTKGPEIRTGLLEGAAQLKS 527
+G +AI +D KGPEIRTG + +LK+
Sbjct: 66 VGR--EIAIMMDIKGPEIRTGDVSSPIELKA 94
Score = 35.9 bits (79), Expect = 1.1
Identities = 21/86 (24%), Positives = 42/86 (48%), Gaps = 3/86 (3%)
Frame = +2
Query: 515 SAEVELKKGETIKLTSSDYQEKGNAD---TIYVDYKNITNVVKPGNRIFIDDGLISIICQ 685
S+ +ELK GE T + +++ ++ V+YK++ N ++ G+ + +D+GLI +
Sbjct: 87 SSPIELKAGEIFDFTIRPGAAQDSSEEVRSVDVNYKDLVNDIRVGDTVLVDNGLIRLEVL 146
Query: 686 SVSADTLTCTIENGGMLGSGKASTCP 763
+ C + G L S + P
Sbjct: 147 EKQNTRIRCRVLIPGELKSRRHINLP 172
>UniRef50_Q8YTZ8 Cluster: Pyruvate kinase; n=3; Nostocaceae|Rep:
Pyruvate kinase - Anabaena sp. (strain PCC 7120)
Length = 476
Score = 70.1 bits (164), Expect = 5e-11
Identities = 38/83 (45%), Positives = 54/83 (65%)
Frame = +3
Query: 255 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 434
+R + IICT+GPA+ LE ++E GMNVAR+NFSHG++++HA+T + R+ SA
Sbjct: 1 MRRTKIICTVGPATSAPERLEALVEAGMNVARLNFSHGAYDFHAQTAQYLRQ----ISAD 56
Query: 435 LGSPFSLAIALDTKGPEIRTGLL 503
P +AI D GP+IR G L
Sbjct: 57 RQKP--VAIMQDLCGPKIRLGTL 77
Score = 38.3 bits (85), Expect = 0.21
Identities = 20/65 (30%), Positives = 34/65 (52%), Gaps = 1/65 (1%)
Frame = +2
Query: 572 QEKGNA-DTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSGK 748
QEKG++ D + + + +V+PG I I+DG + +I AD + + GG+L + K
Sbjct: 95 QEKGSSLDELPLPLPTLFAMVRPGEPILINDGRVKLIVTDRDADRIRAIAKIGGLLSTRK 154
Query: 749 ASTCP 763
P
Sbjct: 155 GVNLP 159
>UniRef50_A7HIL5 Cluster: Pyruvate kinase; n=9; Bacteria|Rep:
Pyruvate kinase - Anaeromyxobacter sp. Fw109-5
Length = 491
Score = 70.1 bits (164), Expect = 5e-11
Identities = 37/86 (43%), Positives = 57/86 (66%)
Frame = +3
Query: 246 VFVIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSY 425
++ +R + I+ T+GPAS + VL++M+ G++VAR+NFSHG HE HA+ + R A
Sbjct: 1 MYPMRRAKIVATLGPASSDPDVLQRMLAAGVDVARLNFSHGRHEDHAQMLDRIRTA---- 56
Query: 426 SAKLGSPFSLAIALDTKGPEIRTGLL 503
S LG ++A+ D +GP+IRTG L
Sbjct: 57 SRHLGR--AVAVLQDLQGPKIRTGPL 80
Score = 47.6 bits (108), Expect = 3e-04
Identities = 24/84 (28%), Positives = 41/84 (48%)
Frame = +2
Query: 512 GSAEVELKKGETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSV 691
G V L+ G + + ++D + KG+A + Y ++ V+PG+R+ +DDGLI +
Sbjct: 83 GREGVRLEAGAELVI-ATDAEVKGDAKLVSTTYPHLAEDVRPGDRLLVDDGLIELRVLET 141
Query: 692 SADTLTCTIENGGMLGSGKASTCP 763
C + GG+L K P
Sbjct: 142 DGVRARCQVVEGGVLREHKGINLP 165
>UniRef50_Q8PYY4 Cluster: Pyruvate kinase; n=3;
Methanosarcinaceae|Rep: Pyruvate kinase - Methanosarcina
mazei (Methanosarcina frisia)
Length = 477
Score = 70.1 bits (164), Expect = 5e-11
Identities = 37/79 (46%), Positives = 51/79 (64%)
Frame = +3
Query: 270 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 449
I+CTIGPAS + ++ K+M GMNVAR+NFSHG E H+ +R R+ + +LG
Sbjct: 10 IVCTIGPASSSEEMIRKLMLAGMNVARINFSHGDFESHSRVVRIIRKV----ADELGR-- 63
Query: 450 SLAIALDTKGPEIRTGLLE 506
++AI D GP+IR G LE
Sbjct: 64 TIAILADLPGPKIRIGKLE 82
Score = 56.4 bits (130), Expect = 7e-07
Identities = 31/88 (35%), Positives = 44/88 (50%)
Frame = +2
Query: 500 LGRGGSAEVELKKGETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISII 679
+G+ V L KG I LT D GN + I V YK + V PG+ I++ DG I ++
Sbjct: 78 IGKLEKEPVMLHKGNPITLTIDD--TPGNEERIPVSYKQLPESVTPGSLIYLSDGFIQLL 135
Query: 680 CQSVSADTLTCTIENGGMLGSGKASTCP 763
C+ V+ + C + GG L S K P
Sbjct: 136 CKEVTGKDVLCEVLIGGELYSHKGLNLP 163
>UniRef50_Q8F253 Cluster: Pyruvate kinase; n=4; Leptospira|Rep:
Pyruvate kinase - Leptospira interrogans
Length = 478
Score = 69.7 bits (163), Expect = 7e-11
Identities = 33/79 (41%), Positives = 49/79 (62%)
Frame = +3
Query: 270 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 449
I+CTIGPAS + + +++ GM++ARMNFSHG+H+ H R+ E+ + F
Sbjct: 14 IVCTIGPASSSEETILSILKAGMDIARMNFSHGTHDSHKRVYDTLRKCEQIFG------F 67
Query: 450 SLAIALDTKGPEIRTGLLE 506
L I D +GP+IRTG L+
Sbjct: 68 PLGIMADLQGPKIRTGKLK 86
>UniRef50_Q40545 Cluster: Pyruvate kinase isozyme A, chloroplast
precursor; n=15; Magnoliophyta|Rep: Pyruvate kinase
isozyme A, chloroplast precursor - Nicotiana tabacum
(Common tobacco)
Length = 593
Score = 69.3 bits (162), Expect = 1e-10
Identities = 37/90 (41%), Positives = 52/90 (57%)
Frame = +3
Query: 258 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 437
R + +ICTIGPA+ LE++ E GMNVAR+N HG+ E+H I R +
Sbjct: 114 RRTKLICTIGPATCGFEQLERLAEGGMNVARINMCHGTREWHRMVIERLRRLNEE----- 168
Query: 438 GSPFSLAIALDTKGPEIRTGLLEGAAQLKS 527
F++AI +DT+G EI G L GA+ K+
Sbjct: 169 -KGFAVAIMMDTEGSEIHMGDLGGASSAKA 197
>UniRef50_Q9KUN0 Cluster: Pyruvate kinase; n=24; cellular
organisms|Rep: Pyruvate kinase - Vibrio cholerae
Length = 470
Score = 68.9 bits (161), Expect = 1e-10
Identities = 38/79 (48%), Positives = 48/79 (60%)
Frame = +3
Query: 270 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 449
I+CTIGP + +V L +++ GMNV R+NFSHG + H I N R+ + K
Sbjct: 6 IVCTIGPKTESVEKLTELVNAGMNVMRLNFSHGDYVEHGTRITNFRKV-MEVTGK----- 59
Query: 450 SLAIALDTKGPEIRTGLLE 506
LAI LDTKGPEIRT LE
Sbjct: 60 QLAILLDTKGPEIRTIKLE 78
Score = 48.8 bits (111), Expect = 1e-04
Identities = 25/81 (30%), Positives = 39/81 (48%)
Frame = +2
Query: 521 EVELKKGETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSAD 700
+V+L G+ T+ D + GN + + V Y + GNRI +DDGLI + + +
Sbjct: 82 DVDLVAGQEFTFTT-DTKVVGNKERVAVTYSGFAKDLNVGNRILVDDGLIEMEVLATTDT 140
Query: 701 TLTCTIENGGMLGSGKASTCP 763
+ C + N G LG K P
Sbjct: 141 EVKCKVLNNGALGENKGVNLP 161
>UniRef50_Q8TJ98 Cluster: Pyruvate kinase; n=2; Methanomicrobia|Rep:
Pyruvate kinase - Methanosarcina acetivorans
Length = 489
Score = 68.9 bits (161), Expect = 1e-10
Identities = 36/79 (45%), Positives = 48/79 (60%)
Frame = +3
Query: 270 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 449
I+CTIGPAS + VL K++ GMNVAR+NFSHG E H + IR R+ +
Sbjct: 22 IVCTIGPASFSEEVLRKLVLAGMNVARINFSHGDFESHGKVIRRVRKVAEELDR------ 75
Query: 450 SLAIALDTKGPEIRTGLLE 506
++AI D GP+IR G L+
Sbjct: 76 TVAILADLPGPKIRVGKLK 94
Score = 56.4 bits (130), Expect = 7e-07
Identities = 28/78 (35%), Positives = 41/78 (52%)
Frame = +2
Query: 530 LKKGETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLT 709
L KG I LT+ + G+ D I V+YK + V PG+ I++ DG I ++C +S +
Sbjct: 100 LHKGNRITLTTDE--TSGSEDRIPVNYKQLPESVSPGSLIYLSDGFIQLLCLEISGKDVV 157
Query: 710 CTIENGGMLGSGKASTCP 763
C + GG L S K P
Sbjct: 158 CEVMVGGQLYSHKGLNLP 175
>UniRef50_Q1AXJ8 Cluster: Pyruvate kinase; n=1; Rubrobacter
xylanophilus DSM 9941|Rep: Pyruvate kinase - Rubrobacter
xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 477
Score = 68.5 bits (160), Expect = 2e-10
Identities = 34/89 (38%), Positives = 57/89 (64%)
Frame = +3
Query: 255 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 434
+R + I+ T+GPA+ + + ++ G++V R+NFSHG+H+ H + R REA +A+
Sbjct: 3 VRRTKIVATLGPATSSEESIGALVRAGVDVMRLNFSHGTHDMHLDNARTVREA----AAE 58
Query: 435 LGSPFSLAIALDTKGPEIRTGLLEGAAQL 521
G ++AI D +GP+IRTG +EG +L
Sbjct: 59 AGR--NVAIMQDLQGPKIRTGEVEGGTEL 85
Score = 48.8 bits (111), Expect = 1e-04
Identities = 28/89 (31%), Positives = 44/89 (49%), Gaps = 3/89 (3%)
Frame = +2
Query: 506 RGGSAE--VELKKGETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISII 679
R G E EL +G + + D+ G+A + Y + VKPG+R+ IDDGLI +
Sbjct: 75 RTGEVEGGTELVEGSRVVIAPGDFV--GDASRLSTSYDRLAQDVKPGHRLLIDDGLIGLR 132
Query: 680 CQSVSAD-TLTCTIENGGMLGSGKASTCP 763
+S+ + + C + GG + S K P
Sbjct: 133 VESIKENGEIVCEVLEGGPVSSHKGLNFP 161
>UniRef50_Q9RR62 Cluster: Pyruvate kinase; n=5; Bacteria|Rep:
Pyruvate kinase - Deinococcus radiodurans
Length = 482
Score = 68.1 bits (159), Expect = 2e-10
Identities = 36/89 (40%), Positives = 53/89 (59%), Gaps = 1/89 (1%)
Frame = +3
Query: 258 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 437
R + I+ T+GPASR+ VL +M++ G+NV R+NFSHG E H +T++ R+ S +
Sbjct: 6 RATKIVATVGPASRSTEVLGRMIDVGLNVVRLNFSHGDLEDHRQTVQMVRDLAVSKGVTI 65
Query: 438 GSPFSLAIALDTKGPEIRTG-LLEGAAQL 521
G I D +GP+IR G EG+ L
Sbjct: 66 G------ILQDLQGPKIRVGRFAEGSVTL 88
Score = 45.6 bits (103), Expect = 0.001
Identities = 25/88 (28%), Positives = 41/88 (46%)
Frame = +2
Query: 500 LGRGGSAEVELKKGETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISII 679
+GR V L G+ +T + + GNA+ + YK + V PG + +DDG +S+
Sbjct: 78 VGRFAEGSVTLNPGQKFVITMDEVE--GNAERVGSTYKGLAGDVTPGMTLLLDDGNMSLR 135
Query: 680 CQSVSADTLTCTIENGGMLGSGKASTCP 763
V + + T+ GG L + K P
Sbjct: 136 VDHVRGNDIQTTVLIGGTLKNNKGINVP 163
>UniRef50_Q2S3S2 Cluster: Pyruvate kinase; n=1; Salinibacter ruber
DSM 13855|Rep: Pyruvate kinase - Salinibacter ruber
(strain DSM 13855)
Length = 476
Score = 68.1 bits (159), Expect = 2e-10
Identities = 31/83 (37%), Positives = 50/83 (60%)
Frame = +3
Query: 258 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 437
R + I+CT+GPA+ + L +++ GM+VARMNFSHG+HE H E + RE ++
Sbjct: 3 RRTKIVCTLGPATTDPETLRRLVAAGMDVARMNFSHGTHEEHRERVETVREVAEAEGK-- 60
Query: 438 GSPFSLAIALDTKGPEIRTGLLE 506
+ + D +GP+IR G ++
Sbjct: 61 ----GITVLQDLQGPKIRVGAVQ 79
Score = 47.6 bits (108), Expect = 3e-04
Identities = 24/80 (30%), Positives = 42/80 (52%)
Frame = +2
Query: 524 VELKKGETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADT 703
V L +G+ +++++ +E N + I++DY+ + + G RI IDDGL+ + +
Sbjct: 83 VMLAEGDEVRVSTDTPRESTN-EHIFIDYEALARDAREGERILIDDGLLELRVIETNGSQ 141
Query: 704 LTCTIENGGMLGSGKASTCP 763
L T+ GG L S K P
Sbjct: 142 LRATVVEGGPLRSRKGVNLP 161
>UniRef50_Q2IHE2 Cluster: Pyruvate kinase; n=1; Anaeromyxobacter
dehalogenans 2CP-C|Rep: Pyruvate kinase -
Anaeromyxobacter dehalogenans (strain 2CP-C)
Length = 489
Score = 68.1 bits (159), Expect = 2e-10
Identities = 37/84 (44%), Positives = 54/84 (64%)
Frame = +3
Query: 255 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 434
+R + I+ T+GPAS VL +++E G++VAR+NFSHG HE HA + R A S
Sbjct: 1 MRRAKIVATLGPASGEPDVLARLLEQGVDVARLNFSHGRHEDHARMLDKIRAA----SRH 56
Query: 435 LGSPFSLAIALDTKGPEIRTGLLE 506
LG ++A+ D +GP+IRTG L+
Sbjct: 57 LGK--AVAVLQDLQGPKIRTGPLK 78
Score = 43.2 bits (97), Expect = 0.007
Identities = 21/86 (24%), Positives = 42/86 (48%)
Frame = +2
Query: 506 RGGSAEVELKKGETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQ 685
+ G A V+++ G+ + +T+ + G+A + Y ++ V+ G+R+ +DDGL+
Sbjct: 78 KAGKAGVQVEAGQELVITTEG-ELPGDAHLVSTTYPHLAEDVRAGDRLLVDDGLLEFRVL 136
Query: 686 SVSADTLTCTIENGGMLGSGKASTCP 763
+ + + GG LG K P
Sbjct: 137 ATDGVRVRTEVVEGGWLGEHKGINLP 162
>UniRef50_Q7UF82 Cluster: Pyruvate kinase; n=1; Pirellula sp.|Rep:
Pyruvate kinase - Rhodopirellula baltica
Length = 476
Score = 67.3 bits (157), Expect = 4e-10
Identities = 35/90 (38%), Positives = 54/90 (60%)
Frame = +3
Query: 258 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 437
R + II TIGPA+ + L ++E G++V R+N +HG+ E+ E + R+ K S
Sbjct: 5 RHTKIIATIGPATESPEKLAALIEAGVDVMRLNMAHGTPEWVGEIVARIRKVSKDISR-- 62
Query: 438 GSPFSLAIALDTKGPEIRTGLLEGAAQLKS 527
+A+ +D KGPEIRTG +E A +LK+
Sbjct: 63 ----HVAVMMDVKGPEIRTGAVEDAIELKA 88
>UniRef50_Q4YDL9 Cluster: Putative uncharacterized protein; n=1;
Plasmodium berghei|Rep: Putative uncharacterized protein
- Plasmodium berghei
Length = 158
Score = 67.3 bits (157), Expect = 4e-10
Identities = 33/78 (42%), Positives = 50/78 (64%)
Frame = +3
Query: 270 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 449
I+CT+GPA ++V L ++++ GM++ R NFSHG+H+ H + N +A+
Sbjct: 41 IVCTLGPACKSVETLVQLIDAGMDICRFNFSHGTHDDH-KMFENVLKAQAQ-----RPNC 94
Query: 450 SLAIALDTKGPEIRTGLL 503
+L + LD KGPEIRTGLL
Sbjct: 95 TLGMLLDNKGPEIRTGLL 112
>UniRef50_Q2JLA2 Cluster: Pyruvate kinase; n=2; Synechococcus|Rep:
Pyruvate kinase - Synechococcus sp. (strain
JA-2-3B'a(2-13)) (Cyanobacteria bacteriumYellowstone
B-Prime)
Length = 619
Score = 66.9 bits (156), Expect = 5e-10
Identities = 39/91 (42%), Positives = 53/91 (58%), Gaps = 1/91 (1%)
Frame = +3
Query: 258 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 437
R + I+ TIGPAS N A+L +M+ G R+NFSHG HE H +IR R+ + L
Sbjct: 8 RRTKIVATIGPASSNPAILREMILQGATTLRLNFSHGDHELHRRSIRLIRQT----AMDL 63
Query: 438 GSPFSLAIALDTKGPEIRTG-LLEGAAQLKS 527
G +AI D +GP+IR G EG+ LK+
Sbjct: 64 G--IQVAILQDLQGPKIRLGKFAEGSITLKA 92
>UniRef50_A0L7K0 Cluster: Pyruvate kinase; n=1; Magnetococcus sp.
MC-1|Rep: Pyruvate kinase - Magnetococcus sp. (strain
MC-1)
Length = 569
Score = 66.5 bits (155), Expect = 7e-10
Identities = 36/89 (40%), Positives = 55/89 (61%)
Frame = +3
Query: 258 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 437
R + I+ T+GPA +V + +++E G++VAR+N SHG H+ H E I N REA S AK
Sbjct: 3 RRAKIVATLGPACSSVEQITRLIEAGLDVARLNMSHGDHKAHLELIHNVREA--SRIAKR 60
Query: 438 GSPFSLAIALDTKGPEIRTGLLEGAAQLK 524
+A+ D +GP+IR G L+ +L+
Sbjct: 61 ----EVALLCDLQGPKIRVGHLDEPLRLE 85
>UniRef50_Q6YQT6 Cluster: Pyruvate kinase; n=6; Candidatus
Phytoplasma|Rep: Pyruvate kinase - Onion yellows
phytoplasma
Length = 446
Score = 66.1 bits (154), Expect = 9e-10
Identities = 35/87 (40%), Positives = 53/87 (60%)
Frame = +3
Query: 270 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 449
IICT+GPAS + +L+ +++TG+NVAR NFSH +E ++ K+ S KL
Sbjct: 6 IICTLGPASYDKNILQALIQTGLNVARFNFSHAQYEQTKLLMKTI----KTISDKLDK-- 59
Query: 450 SLAIALDTKGPEIRTGLLEGAAQLKSN 530
+ + LDTKGPEIRT +G ++ +
Sbjct: 60 NTGLMLDTKGPEIRTHEFDGVVTIQKD 86
Score = 35.5 bits (78), Expect = 1.4
Identities = 17/51 (33%), Positives = 30/51 (58%)
Frame = +2
Query: 524 VELKKGETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISI 676
V ++K +K++ ++ GNA V Y N+ N +K G+ + IDDG +S+
Sbjct: 81 VTIQKDSEVKISMTEVL--GNAKLFSVSYSNLYNELKVGDMVNIDDGYLSL 129
>UniRef50_A6Q7D7 Cluster: Pyruvate kinase; n=19; cellular
organisms|Rep: Pyruvate kinase - Sulfurovum sp. (strain
NBC37-1)
Length = 488
Score = 66.1 bits (154), Expect = 9e-10
Identities = 36/86 (41%), Positives = 51/86 (59%)
Frame = +3
Query: 270 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 449
II TIGPA+ + ++ +M G+N+ R+NFSHG+HEYH+E + R+A + G
Sbjct: 7 IIATIGPATDSYEKIKALMCAGVNLFRLNFSHGTHEYHSEVLGRIRKAIEETGLITG--- 63
Query: 450 SLAIALDTKGPEIRTGLLEGAAQLKS 527
I D GP+IR G+LE LKS
Sbjct: 64 ---ILQDISGPKIRVGMLEEDFILKS 86
Score = 41.5 bits (93), Expect = 0.022
Identities = 23/81 (28%), Positives = 41/81 (50%), Gaps = 3/81 (3%)
Frame = +2
Query: 530 LKKGETIKLTSSD---YQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSAD 700
LK G+ ++ + Y+ K + ++ +I + ++ G I++ DG+I + + SAD
Sbjct: 84 LKSGDILEFVKEEIVGYKVKEGVYRLCINEPDILDQLEVGESIYMYDGIIRAVVKEKSAD 143
Query: 701 TLTCTIENGGMLGSGKASTCP 763
+ IEN GML S K P
Sbjct: 144 MVKVEIENNGMLSSRKGVNFP 164
>UniRef50_A3I0G9 Cluster: Pyruvate kinase; n=3;
Flexibacteraceae|Rep: Pyruvate kinase - Algoriphagus sp.
PR1
Length = 476
Score = 66.1 bits (154), Expect = 9e-10
Identities = 34/79 (43%), Positives = 44/79 (55%)
Frame = +3
Query: 270 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 449
I+ TIGPAS N + + G NV R+NFSHGSH+ H E I R+ K + LG
Sbjct: 11 ILATIGPASNNYETISSLAAAGANVFRLNFSHGSHDIHQEVIEIIRKINKEQNLNLG--- 67
Query: 450 SLAIALDTKGPEIRTGLLE 506
I D +GP+IR G +E
Sbjct: 68 ---ILQDLQGPKIRVGEVE 83
Score = 51.6 bits (118), Expect = 2e-05
Identities = 26/80 (32%), Positives = 41/80 (51%)
Frame = +2
Query: 524 VELKKGETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADT 703
VE+K GE I +T+ G + + Y+N+ V G+RI IDDG + ++
Sbjct: 87 VEIKPGEKITITNDPVV--GTSTLVSTVYQNLPQDVVSGDRILIDDGNLEVVVNDTDGKN 144
Query: 704 LTCTIENGGMLGSGKASTCP 763
+ CT+ +GG+L S K P
Sbjct: 145 VNCTVIHGGILKSRKGINLP 164
>UniRef50_Q5IX04 Cluster: Pyruvate kinase; n=1; Prototheca
wickerhamii|Rep: Pyruvate kinase - Prototheca
wickerhamii
Length = 259
Score = 66.1 bits (154), Expect = 9e-10
Identities = 37/80 (46%), Positives = 49/80 (61%)
Frame = +3
Query: 258 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 437
R + +CTIGP S + ++ + GMNV R+N SHG H H + I RE Y+A L
Sbjct: 100 RKTKTVCTIGPTSCDREAFFRLADAGMNVVRLNMSHGDHASHQQVIDLVRE----YNA-L 154
Query: 438 GSPFSLAIALDTKGPEIRTG 497
G +LAI LDTKGPE+R+G
Sbjct: 155 GRR-NLAIMLDTKGPEVRSG 173
>UniRef50_Q5C2V0 Cluster: Pyruvate kinase; n=1; Schistosoma
japonicum|Rep: Pyruvate kinase - Schistosoma japonicum
(Blood fluke)
Length = 168
Score = 66.1 bits (154), Expect = 9e-10
Identities = 33/85 (38%), Positives = 54/85 (63%)
Frame = +3
Query: 249 FVIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYS 428
F +R + ++CT+G + +++M+++GMN+ R+N S G+ E +AE IR R E+SY
Sbjct: 40 FFVRHTNLVCTLGDHWDSDEKIDQMIKSGMNILRLNLSMGTKEKYAEVIRRVRRLEESYD 99
Query: 429 AKLGSPFSLAIALDTKGPEIRTGLL 503
+P S+ IALD P +RTGL+
Sbjct: 100 Y---NP-SVGIALDLSAPPVRTGLI 120
>UniRef50_Q6KHW9 Cluster: Pyruvate kinase; n=3; Mycoplasma|Rep:
Pyruvate kinase - Mycoplasma mobile
Length = 483
Score = 65.7 bits (153), Expect = 1e-09
Identities = 39/85 (45%), Positives = 51/85 (60%)
Frame = +3
Query: 264 SGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGS 443
S +I TIGP+S+N +L++MM GM R NFSHG HAE + N K + +L
Sbjct: 17 SKMIATIGPSSQNKEILKQMMLKGMTTVRANFSHGD---HAEQL-NKFVLAKEVAKELNL 72
Query: 444 PFSLAIALDTKGPEIRTGLLEGAAQ 518
P SL LDTKGPEIR G ++ +Q
Sbjct: 73 PMSL--MLDTKGPEIRVGKMKDGSQ 95
>UniRef50_Q46078 Cluster: Pyruvate kinase; n=19; Actinobacteria
(class)|Rep: Pyruvate kinase - Corynebacterium
glutamicum (Brevibacterium flavum)
Length = 475
Score = 65.3 bits (152), Expect = 2e-09
Identities = 29/88 (32%), Positives = 47/88 (53%)
Frame = +2
Query: 500 LGRGGSAEVELKKGETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISII 679
LGR + GETI++T D + G D + YKN+ KPG+R+ +DDG + ++
Sbjct: 75 LGRFTDGATVWENGETIRITVDDVE--GTHDRVSTTYKNLAKDAKPGDRLLVDDGKVGLV 132
Query: 680 CQSVSADTLTCTIENGGMLGSGKASTCP 763
C SV + + C + GG + + K + P
Sbjct: 133 CVSVEGNDVICEVVEGGPVSNNKGVSLP 160
Score = 62.1 bits (144), Expect = 1e-08
Identities = 33/91 (36%), Positives = 50/91 (54%)
Frame = +3
Query: 258 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 437
R + I+CT+GPA + + +++E GM+VAR+NFSHG H H + + REA + +
Sbjct: 3 RRTKIVCTLGPAVASADGILRLVEDGMDVARLNFSHGDHPDHEQNYKWVREAAEKTGRAV 62
Query: 438 GSPFSLAIALDTKGPEIRTGLLEGAAQLKSN 530
G I D +GP+IR G A + N
Sbjct: 63 G------ILADLQGPKIRLGRFTDGATVWEN 87
>UniRef50_Q82XE9 Cluster: Pyruvate kinase family; n=130;
Proteobacteria|Rep: Pyruvate kinase family -
Nitrosomonas europaea
Length = 496
Score = 64.5 bits (150), Expect = 3e-09
Identities = 35/93 (37%), Positives = 58/93 (62%), Gaps = 1/93 (1%)
Frame = +3
Query: 252 VIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSA 431
++R + I+ T+GPAS N VL +M+E G++V R+NFSHG+ + H ++ E +S +
Sbjct: 1 MMRRTKIVATLGPASSNAEVLGRMLEAGVDVIRINFSHGTKDEHIASV----ELVRSLAR 56
Query: 432 KLGSPFSLAIALDTKGPEIRTGLLE-GAAQLKS 527
LG ++ + D +GP+IR G E G +LK+
Sbjct: 57 SLGR--TVGVLADLQGPKIRIGKFEQGKIRLKT 87
Score = 44.8 bits (101), Expect = 0.002
Identities = 22/83 (26%), Positives = 42/83 (50%)
Frame = +2
Query: 500 LGRGGSAEVELKKGETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISII 679
+G+ ++ LK G+ L + + GN + + +DY+ + N V+ G + +DDG I +
Sbjct: 75 IGKFEQGKIRLKTGDEFILDAEC--QLGNQERVGLDYRELPNDVEAGATLLLDDGRIVLT 132
Query: 680 CQSVSADTLTCTIENGGMLGSGK 748
V + C + GG+L + K
Sbjct: 133 VAKVRESEIFCEVLQGGILSNNK 155
>UniRef50_Q6A9P1 Cluster: Pyruvate kinase; n=4; Actinomycetales|Rep:
Pyruvate kinase - Propionibacterium acnes
Length = 477
Score = 64.5 bits (150), Expect = 3e-09
Identities = 34/86 (39%), Positives = 54/86 (62%)
Frame = +3
Query: 255 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 434
+R + I+ T+GPA + ++++ME GMN+AR+N SHG + H E + + +S S +
Sbjct: 1 MRRAKIVNTLGPAVTSHDAMKELMEAGMNIARLNMSHGDYSEHQERL----DLVRSVSKE 56
Query: 435 LGSPFSLAIALDTKGPEIRTGLLEGA 512
LG ++A D +GP+IRTGL E A
Sbjct: 57 LG--LNVAALADLQGPKIRTGLFEKA 80
Score = 45.2 bits (102), Expect = 0.002
Identities = 24/83 (28%), Positives = 40/83 (48%)
Frame = +2
Query: 515 SAEVELKKGETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVS 694
+ +++LK G+ +T+ D GN + + +K + KPG+ I IDDG + SVS
Sbjct: 85 NGKIDLKIGDKFTITTDDIV--GNQERVSTTFKGLPQDCKPGDVILIDDGKTVLQVDSVS 142
Query: 695 ADTLTCTIENGGMLGSGKASTCP 763
+ + C G +G K P
Sbjct: 143 GNDVNCHCTVAGPVGDHKGINLP 165
>UniRef50_Q0C0E8 Cluster: Pyruvate kinase; n=1; Hyphomonas neptunium
ATCC 15444|Rep: Pyruvate kinase - Hyphomonas neptunium
(strain ATCC 15444)
Length = 474
Score = 64.5 bits (150), Expect = 3e-09
Identities = 36/91 (39%), Positives = 53/91 (58%)
Frame = +3
Query: 270 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 449
I+ T+GP SR+ + + E G++V R+NFSHG H H E ++ R AE A +G P
Sbjct: 13 IVATLGPGSRSPREVRALAEAGVDVFRLNFSHGEHAAHLEALKAVRAAE----AAVGWP- 67
Query: 450 SLAIALDTKGPEIRTGLLEGAAQLKSN*RRE 542
LA D +GP++R G +G + LK R+E
Sbjct: 68 -LATLADLQGPKVRVGKFDGGS-LKLGFRKE 96
>UniRef50_P19680 Cluster: Pyruvate kinase; n=1; Spiroplasma
citri|Rep: Pyruvate kinase - Spiroplasma citri
Length = 192
Score = 64.1 bits (149), Expect = 4e-09
Identities = 34/73 (46%), Positives = 44/73 (60%)
Frame = +3
Query: 270 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 449
II TIGP++ + +E++ +TGM R+NFSHG H I RE SAK+G P
Sbjct: 15 IITTIGPSTHSPGAIEELFKTGMTTIRLNFSHGDHAEQGARIVWAREV----SAKIGKPI 70
Query: 450 SLAIALDTKGPEI 488
S + LDTKGPEI
Sbjct: 71 S--VLLDTKGPEI 81
>UniRef50_A4MK73 Cluster: Pyruvate kinase; n=1; Petrotoga mobilis
SJ95|Rep: Pyruvate kinase - Petrotoga mobilis SJ95
Length = 478
Score = 63.7 bits (148), Expect = 5e-09
Identities = 33/79 (41%), Positives = 50/79 (63%)
Frame = +3
Query: 270 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 449
I+CTIGPA+++ +++K++ GMNVAR+N SH + H + + ++ K L PF
Sbjct: 12 IVCTIGPATQDETMIKKLINAGMNVARLNTSHDTIADHEKRVNLIKKIRKD----LNIPF 67
Query: 450 SLAIALDTKGPEIRTGLLE 506
AI LD +GP+IRTG E
Sbjct: 68 --AILLDLEGPKIRTGKFE 84
Score = 39.5 bits (88), Expect = 0.089
Identities = 21/87 (24%), Positives = 43/87 (49%)
Frame = +2
Query: 503 GRGGSAEVELKKGETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIIC 682
G+ + +V L++G+ LT + GN + + ++Y+ + VK G+ I +DDG I ++
Sbjct: 81 GKFETDQVMLEEGQKFILTIEEIV--GNKERVSINYRELPKEVKKGDFILLDDGKIRLVV 138
Query: 683 QSVSADTLTCTIENGGMLGSGKASTCP 763
S + + + GG + + P
Sbjct: 139 VSSNEKEIVTKVVTGGSITHRRGINVP 165
>UniRef50_Q44473 Cluster: Pyruvate kinase; n=4; Proteobacteria|Rep:
Pyruvate kinase - Agrobacterium vitis (Rhizobium vitis)
Length = 482
Score = 63.3 bits (147), Expect = 6e-09
Identities = 32/82 (39%), Positives = 49/82 (59%)
Frame = +3
Query: 258 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 437
R S I+ T+GPAS + +L + G++ R+NFSHG+ HAE RN R E+ + A
Sbjct: 7 RRSKIVATVGPASSSPDMLRSLFLAGVDTFRLNFSHGARADHAEVYRNIRALEQEHDA-- 64
Query: 438 GSPFSLAIALDTKGPEIRTGLL 503
++A+ D +GP+IR G+L
Sbjct: 65 ----AIAVLQDLQGPKIRIGVL 82
Score = 40.7 bits (91), Expect = 0.038
Identities = 25/80 (31%), Positives = 36/80 (45%)
Frame = +2
Query: 524 VELKKGETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADT 703
++L +G TI +G D I + ++ I V PG + IDDG I + V
Sbjct: 87 LDLARGSTIGFILGREGGEGMND-IPLPHREIFEVAVPGMDLLIDDGRIKVRIMEVMDGR 145
Query: 704 LTCTIENGGMLGSGKASTCP 763
L C + NGG L + K P
Sbjct: 146 LVCEVLNGGALSNRKGVNVP 165
>UniRef50_Q1IJ65 Cluster: Pyruvate kinase; n=6; Bacteria|Rep:
Pyruvate kinase - Acidobacteria bacterium (strain
Ellin345)
Length = 485
Score = 62.9 bits (146), Expect = 8e-09
Identities = 33/79 (41%), Positives = 50/79 (63%)
Frame = +3
Query: 270 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 449
I+ TIGPAS + +LE+++ TG++VAR+NFSHG H E I N R A S + G
Sbjct: 10 IVGTIGPASESPEMLERLIRTGLDVARLNFSHGDFSGHRERIANLRAA----SDRAGR-- 63
Query: 450 SLAIALDTKGPEIRTGLLE 506
++A+ D GP++R G ++
Sbjct: 64 AVAVLADLPGPKMRLGTIQ 82
Score = 46.0 bits (104), Expect = 0.001
Identities = 23/88 (26%), Positives = 44/88 (50%)
Frame = +2
Query: 500 LGRGGSAEVELKKGETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISII 679
LG + + L+ G+ LT+ G+ + + + VVKPG+R++++DGL+ ++
Sbjct: 78 LGTIQNEPIHLRAGDPFTLTTDSIV--GDNRRCSMSFAALPQVVKPGDRLYLNDGLVHLL 135
Query: 680 CQSVSADTLTCTIENGGMLGSGKASTCP 763
+ + + C + GG L S K P
Sbjct: 136 VERIEGTDVHCVVAVGGELRSRKGLNLP 163
>UniRef50_A6C474 Cluster: Pyruvate kinase; n=1; Planctomyces maris
DSM 8797|Rep: Pyruvate kinase - Planctomyces maris DSM
8797
Length = 489
Score = 62.9 bits (146), Expect = 8e-09
Identities = 32/80 (40%), Positives = 52/80 (65%)
Frame = +3
Query: 270 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 449
II T+GPAS + +L+K++ G+++ R+NF+HG HE+ +E ++N E SA++ P
Sbjct: 17 IIATVGPASDSREMLQKLIIAGVDLFRLNFAHGKHEWLSEIVKNIHE----ISAEMEKP- 71
Query: 450 SLAIALDTKGPEIRTGLLEG 509
+ I D GP+IR G+L G
Sbjct: 72 -IGILGDLSGPKIRLGVLPG 90
>UniRef50_P73534 Cluster: Pyruvate kinase 2; n=37; Bacteria|Rep:
Pyruvate kinase 2 - Synechocystis sp. (strain PCC 6803)
Length = 591
Score = 62.9 bits (146), Expect = 8e-09
Identities = 35/93 (37%), Positives = 55/93 (59%), Gaps = 3/93 (3%)
Frame = +3
Query: 258 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 437
R + I+ TIGPA+++ VL ++++ G R+NFSHG H YH ++IR R+ + +L
Sbjct: 8 RRTKIVATIGPATQSKEVLRQLIQAGATTFRLNFSHGDHAYHQQSIRLIRQ----IAFEL 63
Query: 438 GSPFSLAIALDTKGPEIRTGLL---EGAAQLKS 527
P + I D +GP+IR G G+ QLK+
Sbjct: 64 NQP--VGILQDLQGPKIRVGKFLNDAGSVQLKN 94
>UniRef50_Q2TSW6 Cluster: Pyruvate kinase; n=1; Achlya
bisexualis|Rep: Pyruvate kinase - Achlya bisexualis
(Water mold)
Length = 517
Score = 62.5 bits (145), Expect = 1e-08
Identities = 35/92 (38%), Positives = 53/92 (57%), Gaps = 6/92 (6%)
Frame = +2
Query: 506 RGGS---AEVELKKGETIKLTSS-DYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLIS 673
RGG+ ++ L KG+ I LT+ Y+E D +YV Y+ + VK G+ + +DDGLIS
Sbjct: 107 RGGAFPEKKINLTKGDMITLTTDVQYKEASTKDMLYVTYEQLPATVKVGDTVLLDDGLIS 166
Query: 674 IICQS--VSADTLTCTIENGGMLGSGKASTCP 763
+ +S V++ + C IEN +LGS K P
Sbjct: 167 LTVKSIDVASGQVRCLIENSEVLGSRKGVNLP 198
Score = 56.4 bits (130), Expect = 7e-07
Identities = 25/80 (31%), Positives = 48/80 (60%), Gaps = 1/80 (1%)
Frame = +3
Query: 261 LSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLG 440
++ I+ T+GP S N +++ G+ + R+NFSH +++ + + R ++ ++ G
Sbjct: 30 MTKIVGTVGPVSENAKTTQELTNAGLKIMRINFSHATYDEAHLRMSHLRASKGVHAKHTG 89
Query: 441 SPFSL-AIALDTKGPEIRTG 497
F++ A+ LDT+GPEIR G
Sbjct: 90 KEFNVRAVLLDTQGPEIRGG 109
>UniRef50_Q5V4I8 Cluster: Pyruvate kinase; n=4;
Halobacteriaceae|Rep: Pyruvate kinase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 610
Score = 62.5 bits (145), Expect = 1e-08
Identities = 33/89 (37%), Positives = 52/89 (58%)
Frame = +3
Query: 255 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 434
+R + I+CT+GPAS +V + + + GM+VAR+N SHGS E+ E I R+ +++
Sbjct: 15 MRSAKIVCTLGPASDSVDDIASLAKAGMSVARLNASHGSPEHRREMIDRIRQVDEAVEE- 73
Query: 435 LGSPFSLAIALDTKGPEIRTGLLEGAAQL 521
+A LD GPE+RT ++ QL
Sbjct: 74 -----PVAAMLDMPGPEVRTAEIDEPIQL 97
Score = 45.6 bits (103), Expect = 0.001
Identities = 25/80 (31%), Positives = 39/80 (48%)
Frame = +2
Query: 524 VELKKGETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADT 703
++L +G TI+ D +A V V+PG+R+ +DDG I + V +T
Sbjct: 95 IQLTEGSTIRYVVGD-----DATPEEVGLSQSITAVEPGDRVLLDDGRIETTVERVEDET 149
Query: 704 LTCTIENGGMLGSGKASTCP 763
+ T+ENGG L + K P
Sbjct: 150 VFATVENGGELAARKGVNVP 169
>UniRef50_Q56301 Cluster: Pyruvate kinase; n=5; Thermococcaceae|Rep:
Pyruvate kinase - Thermococcus litoralis
Length = 220
Score = 62.5 bits (145), Expect = 1e-08
Identities = 33/80 (41%), Positives = 50/80 (62%)
Frame = +3
Query: 270 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 449
II TIGPAS+ ++KM++ GM+VAR+NFSHG+ E HA+TI R+ + +
Sbjct: 14 IIATIGPASKQKESIKKMIKAGMSVARINFSHGTLEEHAKTIETVRDVAEKLERR----- 68
Query: 450 SLAIALDTKGPEIRTGLLEG 509
+AI D G ++R G ++G
Sbjct: 69 -VAILGDLPGLKMRVGKIKG 87
Score = 56.0 bits (129), Expect = 1e-06
Identities = 28/88 (31%), Positives = 50/88 (56%)
Frame = +2
Query: 500 LGRGGSAEVELKKGETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISII 679
+G+ V L+KG+ + LT+ D + G+ TI V++K++ +V G+ I++ DG I +
Sbjct: 82 VGKIKGDSVTLRKGDKVVLTTRDIE--GDETTIPVEFKDLPKLVSKGDTIYLSDGYIMLR 139
Query: 680 CQSVSADTLTCTIENGGMLGSGKASTCP 763
+ V + + C + NGG+L S K P
Sbjct: 140 VEEVRENEVECVVVNGGILFSHKGINIP 167
>UniRef50_Q81N35 Cluster: Pyruvate kinase; n=11; Bacillus cereus
group|Rep: Pyruvate kinase - Bacillus anthracis
Length = 352
Score = 62.1 bits (144), Expect = 1e-08
Identities = 31/79 (39%), Positives = 45/79 (56%)
Frame = +3
Query: 273 ICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 452
+CTIGPAS N L K++ GM + R+N SHG+HE H + IR + + S
Sbjct: 6 VCTIGPASNNKETLAKLINNGMKIVRLNLSHGTHESHKDIIRLVKSLDD----------S 55
Query: 453 LAIALDTKGPEIRTGLLEG 509
+ I D +GP+IR G ++G
Sbjct: 56 IKILGDVQGPKIRLGEIKG 74
Score = 51.6 bits (118), Expect = 2e-05
Identities = 27/88 (30%), Positives = 46/88 (52%)
Frame = +2
Query: 500 LGRGGSAEVELKKGETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISII 679
LG ++ L+ G++ L + G++ VDY+ I N VK G+RI ++DG + +I
Sbjct: 69 LGEIKGEQITLQAGDSFMLRTQPVT--GSSTEASVDYEGIANDVKVGSRILMNDGEVELI 126
Query: 680 CQSVSADTLTCTIENGGMLGSGKASTCP 763
+ VS D + ++ GG + S K P
Sbjct: 127 VEKVSTDKIETKVKTGGNISSHKGVNLP 154
>UniRef50_A1BQT0 Cluster: Pyruvate kinase; n=2; Eukaryota|Rep:
Pyruvate kinase - Monocercomonoides sp. PA203
Length = 516
Score = 62.1 bits (144), Expect = 1e-08
Identities = 30/83 (36%), Positives = 49/83 (59%)
Frame = +3
Query: 261 LSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLG 440
L+ I+ T+GPA+ + +++ G+NV RMNFSHG+HE+H + + R+ + LG
Sbjct: 37 LTKIVATLGPATSTYETISQVVTAGVNVIRMNFSHGTHEFHEQLYKIVRKVAED----LG 92
Query: 441 SPFSLAIALDTKGPEIRTGLLEG 509
+AI D +GP++RT G
Sbjct: 93 K--EVAIIADLQGPKVRTNTFPG 113
Score = 42.7 bits (96), Expect = 0.010
Identities = 22/81 (27%), Positives = 37/81 (45%)
Frame = +2
Query: 521 EVELKKGETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSAD 700
++ +K+G+ + + S E G I + + G + IDDGLI +I Q + +
Sbjct: 115 KITIKRGDKVSIVGSP--EPGKPGVITTKFTPMITHCNVGEPVLIDDGLIRLIVQEKNPN 172
Query: 701 TLTCTIENGGMLGSGKASTCP 763
L C +E GG + K P
Sbjct: 173 ELVCLVEQGGDVKDHKGINLP 193
>UniRef50_Q747D6 Cluster: Pyruvate kinase; n=6;
Desulfuromonadales|Rep: Pyruvate kinase - Geobacter
sulfurreducens
Length = 480
Score = 61.7 bits (143), Expect = 2e-08
Identities = 32/87 (36%), Positives = 50/87 (57%)
Frame = +2
Query: 503 GRGGSAEVELKKGETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIIC 682
GR + + L +G+++ +T+ + G I Y+++ + VKPG+RI +DDGLI +
Sbjct: 79 GRMENGAIPLVRGDSLDITTDEVL--GRPGLISTIYQSLPHDVKPGSRILLDDGLIELRV 136
Query: 683 QSVSADTLTCTIENGGMLGSGKASTCP 763
QSVS T+ CT+ GGML K P
Sbjct: 137 QSVSGATVRCTVVQGGMLKDLKGINLP 163
Score = 60.5 bits (140), Expect = 4e-08
Identities = 33/86 (38%), Positives = 52/86 (60%)
Frame = +3
Query: 258 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 437
R + II T+GP S + ++ ++M+ G++V R+NFSHGS++ E I A + SA+
Sbjct: 6 RKTKIIATLGPVSSSPDMIRQLMDAGVDVFRLNFSHGSNDQRREVI----AAIRRLSAER 61
Query: 438 GSPFSLAIALDTKGPEIRTGLLEGAA 515
G + I D +GP+IRTG +E A
Sbjct: 62 GK--EIGILADLQGPKIRTGRMENGA 85
>UniRef50_A6Q5W9 Cluster: Pyruvate kinase; n=2;
Epsilonproteobacteria|Rep: Pyruvate kinase -
Nitratiruptor sp. (strain SB155-2)
Length = 458
Score = 61.7 bits (143), Expect = 2e-08
Identities = 34/87 (39%), Positives = 53/87 (60%)
Frame = +3
Query: 261 LSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLG 440
++ I+ TIGP+S + ++K++ G+NV R+NFSH H+ H +I+ RE K KLG
Sbjct: 1 MTKIVATIGPSS--IEKIDKLILAGVNVFRLNFSHADHKTHKASIKKIRETAK----KLG 54
Query: 441 SPFSLAIALDTKGPEIRTGLLEGAAQL 521
+ AI D GP+IR G ++G +L
Sbjct: 55 T--KTAILQDISGPKIRIGEVDGILEL 79
>UniRef50_Q2FMN4 Cluster: Pyruvate kinase; n=1; Methanospirillum
hungatei JF-1|Rep: Pyruvate kinase - Methanospirillum
hungatei (strain JF-1 / DSM 864)
Length = 500
Score = 61.7 bits (143), Expect = 2e-08
Identities = 30/79 (37%), Positives = 49/79 (62%)
Frame = +3
Query: 255 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 434
+R + II TIGPAS N ++ +M+ +GM++AR+N SHGS +H ET++ R + +
Sbjct: 32 MRRTKIIATIGPASSNPRIIREMILSGMDIARLNLSHGSPPWHEETVQQIRALADELNRE 91
Query: 435 LGSPFSLAIALDTKGPEIR 491
+G I +D GP++R
Sbjct: 92 IG------ILVDIPGPKLR 104
>UniRef50_UPI0000D56D72 Cluster: PREDICTED: similar to CG7070-PB,
isoform B; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG7070-PB, isoform B - Tribolium castaneum
Length = 535
Score = 61.3 bits (142), Expect = 3e-08
Identities = 28/73 (38%), Positives = 47/73 (64%), Gaps = 1/73 (1%)
Frame = +2
Query: 521 EVELKKGETIKLTSS-DYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSA 697
E+EL+KG+T K+ + ++ + + + IYV+Y+NI +VVKPG+ + I D I + V+
Sbjct: 146 EIELEKGQTTKIVAKPEFANRVSKEFIYVNYENIADVVKPGDSLIIGDDNIRMSAIEVAR 205
Query: 698 DTLTCTIENGGML 736
D + C IE G+L
Sbjct: 206 DIINCIIEKAGLL 218
Score = 37.9 bits (84), Expect = 0.27
Identities = 19/72 (26%), Positives = 35/72 (48%)
Frame = +3
Query: 288 PASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIAL 467
P ++ +E+ ++ GM VA + + + + E + R + K+G + +AI L
Sbjct: 69 PPRISIEHIEEFLKAGMTVALIRMDYFTVDEIEEMVAMIRNVVDDFGKKIGRVYPIAIGL 128
Query: 468 DTKGPEIRTGLL 503
D EI+TG L
Sbjct: 129 DVSEQEIKTGKL 140
>UniRef50_Q6AII5 Cluster: Pyruvate kinase; n=1; Desulfotalea
psychrophila|Rep: Pyruvate kinase - Desulfotalea
psychrophila
Length = 581
Score = 61.3 bits (142), Expect = 3e-08
Identities = 33/79 (41%), Positives = 46/79 (58%)
Frame = +3
Query: 270 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 449
II T+GP S++V + +++ GMNVAR+N SHG E + I N +EA K +
Sbjct: 6 IIATLGPQSQSVEEIYSLIQAGMNVARINLSHGDAESYKHLISNVKEARKL------AEK 59
Query: 450 SLAIALDTKGPEIRTGLLE 506
AI LD +GPEIR +E
Sbjct: 60 DTAILLDNRGPEIRVSEME 78
Score = 35.9 bits (79), Expect = 1.1
Identities = 20/81 (24%), Positives = 40/81 (49%)
Frame = +2
Query: 521 EVELKKGETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSAD 700
++ L GE + +T+ E + I +Y + V+ G+RI +DDG +++ ++ +
Sbjct: 80 DIHLVDGEELVITNR--AETVSPSRITTNYPQLAGDVQVGSRILLDDGKLALEVLAIEDE 137
Query: 701 TLTCTIENGGMLGSGKASTCP 763
+ + GG+L S K P
Sbjct: 138 EVITKVIAGGILSSRKRVALP 158
>UniRef50_Q6F1U1 Cluster: Pyruvate kinase; n=10; Mollicutes|Rep:
Pyruvate kinase - Mesoplasma florum (Acholeplasma
florum)
Length = 478
Score = 60.9 bits (141), Expect = 3e-08
Identities = 33/93 (35%), Positives = 52/93 (55%), Gaps = 1/93 (1%)
Frame = +3
Query: 255 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 434
++ + II T GP++ + ++ E GM R+NFSHG +E I ++ + +
Sbjct: 10 VKRTKIITTTGPSTNEPEQIRELFENGMTTIRLNFSHGDYEEQGYRIAGAKKVRE----E 65
Query: 435 LGSPFSLAIALDTKGPEIRTG-LLEGAAQLKSN 530
LG P S I LDTKGPEIR G ++G ++ +N
Sbjct: 66 LGKPVS--ILLDTKGPEIRVGKFVDGKQEVTAN 96
>UniRef50_A7D456 Cluster: Pyruvate kinase; n=2;
Halobacteriaceae|Rep: Pyruvate kinase - Halorubrum
lacusprofundi ATCC 49239
Length = 613
Score = 60.9 bits (141), Expect = 3e-08
Identities = 32/89 (35%), Positives = 51/89 (57%)
Frame = +3
Query: 255 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 434
+R + I+CTIGPAS + + + + GM+V R+N SHG+ + E I R + +
Sbjct: 29 MRNAKIVCTIGPASDSRDAIRDLADAGMSVVRLNASHGTTAHREEVIERARAVDN----E 84
Query: 435 LGSPFSLAIALDTKGPEIRTGLLEGAAQL 521
+ P LA+ +D KGPE+RT L+ + L
Sbjct: 85 IDDP--LAVMVDLKGPEVRTAELDESISL 111
Score = 34.3 bits (75), Expect = 3.3
Identities = 14/43 (32%), Positives = 23/43 (53%)
Frame = +2
Query: 635 PGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSGKASTCP 763
PG+ + +DDG I + V +++ T+ +GG L S K P
Sbjct: 141 PGDTVLLDDGRIECRVERVDGESVVATVVSGGKLSSRKGVNLP 183
>UniRef50_Q2I6K6 Cluster: Pyruvate kinase; n=1; uncultured delta
proteobacterium DeepAnt-32C6|Rep: Pyruvate kinase -
uncultured delta proteobacterium DeepAnt-32C6
Length = 466
Score = 60.5 bits (140), Expect = 4e-08
Identities = 34/90 (37%), Positives = 52/90 (57%), Gaps = 1/90 (1%)
Frame = +3
Query: 255 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 434
+R + I+CTIGPA+ + +++ GM+ AR+NFSHG+ + HA RE + +
Sbjct: 1 MRRAKIVCTIGPATHTREGIRALIDAGMDCARLNFSHGTQQGHARVAALVRE----LATE 56
Query: 435 LGSPFSLAIALDTKGPEIRTGLL-EGAAQL 521
G P +A+ D GP+IR G EGA +L
Sbjct: 57 AGRP--IALLADLCGPKIRVGRFPEGAVEL 84
Score = 54.0 bits (124), Expect = 4e-06
Identities = 30/88 (34%), Positives = 42/88 (47%)
Frame = +2
Query: 500 LGRGGSAEVELKKGETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISII 679
+GR VEL +G LT+ D G ++Y + V PG+ I IDDGLI ++
Sbjct: 74 VGRFPEGAVELVEGTAFTLTTRDVA--GTDKQASINYAALPQDVDPGDAIMIDDGLIRLV 131
Query: 680 CQSVSADTLTCTIENGGMLGSGKASTCP 763
+ V + C +E GGML K P
Sbjct: 132 VREVEGPDIHCIVEVGGMLSERKGINVP 159
>UniRef50_Q94KE3 Cluster: Pyruvate kinase; n=25; Magnoliophyta|Rep:
Pyruvate kinase - Arabidopsis thaliana (Mouse-ear cress)
Length = 527
Score = 60.5 bits (140), Expect = 4e-08
Identities = 38/95 (40%), Positives = 56/95 (58%), Gaps = 1/95 (1%)
Frame = +3
Query: 249 FVIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYS 428
F L+ I+ T+GP SR+V L ++ GM+VAR +FS G +YH ET+ N + A +S +
Sbjct: 25 FFPALTKIVGTLGPKSRSVEALSGCLKAGMSVARFDFSWGDADYHQETLDNLKVAVRS-T 83
Query: 429 AKLGSPFSLAIALDTKGPEIRT-GLLEGAAQLKSN 530
KL A+ LDT GPE++ E A LK++
Sbjct: 84 KKL-----CAVMLDTVGPELQVINKSEKAITLKAD 113
>UniRef50_Q63P20 Cluster: Pyruvate kinase; n=74; Proteobacteria|Rep:
Pyruvate kinase - Burkholderia pseudomallei (Pseudomonas
pseudomallei)
Length = 484
Score = 59.7 bits (138), Expect = 8e-08
Identities = 32/89 (35%), Positives = 53/89 (59%), Gaps = 1/89 (1%)
Frame = +3
Query: 258 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 437
R + I+ T+GP+S +E + G +V R+NFSHG+H HA +R+ A ++ A++
Sbjct: 13 RSTKIVATLGPSSSTETAIEALARAGADVFRLNFSHGTHADHA--LRHA--AVRAIEARI 68
Query: 438 GSPFSLAIALDTKGPEIRTG-LLEGAAQL 521
G P + + LD +GP++R G G AQ+
Sbjct: 69 GHP--IGVLLDLQGPKLRVGQFASGRAQI 95
>UniRef50_Q2TSX0 Cluster: Pyruvate kinase; n=2; cellular
organisms|Rep: Pyruvate kinase - Phaeodactylum
tricornutum
Length = 665
Score = 59.7 bits (138), Expect = 8e-08
Identities = 31/75 (41%), Positives = 44/75 (58%)
Frame = +3
Query: 273 ICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 452
+ T+GPAS N ++EK+ G +V R+NFSHGS E E + RE E+ YS +G
Sbjct: 158 VVTLGPASSNKEMIEKLFLAGADVFRLNFSHGSQEQKKELLIMIREVEEKYSHPIG---- 213
Query: 453 LAIALDTKGPEIRTG 497
I D +GP++R G
Sbjct: 214 --ILGDLQGPKLRVG 226
Score = 35.1 bits (77), Expect = 1.9
Identities = 17/78 (21%), Positives = 37/78 (47%)
Frame = +2
Query: 530 LKKGETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLT 709
L+ G++ +L + KG+ + + + I + G+ + +DDG + ++ + D L
Sbjct: 236 LELGQSFRLDLDN--AKGDNKRVQLPHPEIIKASELGHALLVDDGKVKLVVTAKGDDYLE 293
Query: 710 CTIENGGMLGSGKASTCP 763
C ++ GM+ K P
Sbjct: 294 CRVDVAGMIKDRKGVNTP 311
>UniRef50_A6DH47 Cluster: Pyruvate kinase; n=1; Lentisphaera
araneosa HTCC2155|Rep: Pyruvate kinase - Lentisphaera
araneosa HTCC2155
Length = 485
Score = 59.3 bits (137), Expect = 1e-07
Identities = 34/87 (39%), Positives = 53/87 (60%), Gaps = 1/87 (1%)
Frame = +3
Query: 270 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 449
I+ T+GP ++ L++++E G++V R+NFSHGSHE HAE I+ A +G
Sbjct: 9 IVSTLGPTTKGR--LKELIEEGVDVFRLNFSHGSHEEHAERIQEVISAATELKRTVG--- 63
Query: 450 SLAIALDTKGPEIRTG-LLEGAAQLKS 527
I D +GP+IR G ++EG QL++
Sbjct: 64 ---ILGDLQGPKIRCGKIIEGGIQLEA 87
Score = 37.9 bits (84), Expect = 0.27
Identities = 19/80 (23%), Positives = 41/80 (51%)
Frame = +2
Query: 524 VELKKGETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADT 703
++L+ G+ + +T+ + +G+ I ++ + VK G+ I +DDGL+ + + + +
Sbjct: 83 IQLEAGQELVITTDEILGEGSR--ISTVFQALPREVKVGDPILMDDGLLEAVVERIEGNE 140
Query: 704 LTCTIENGGMLGSGKASTCP 763
+ C + G L S K P
Sbjct: 141 IFCKMLVAGKLTSNKGINLP 160
>UniRef50_Q9YEU2 Cluster: Pyruvate kinase; n=1; Aeropyrum
pernix|Rep: Pyruvate kinase - Aeropyrum pernix
Length = 458
Score = 59.3 bits (137), Expect = 1e-07
Identities = 27/76 (35%), Positives = 48/76 (63%)
Frame = +3
Query: 270 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 449
I+ T+GP+S + ++L +M+ G++VAR+N SHG E + + R AE++ ++G
Sbjct: 7 IVATVGPSSSSASILAQMLSLGVDVARINASHGGVEQWNSMLESLRRAEEAVGKRVG--- 63
Query: 450 SLAIALDTKGPEIRTG 497
+A+D +GP +RTG
Sbjct: 64 ---VAVDLEGPRVRTG 76
Score = 33.5 bits (73), Expect = 5.8
Identities = 22/80 (27%), Positives = 38/80 (47%)
Frame = +2
Query: 509 GGSAEVELKKGETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQS 688
G S V+L+KG+ + L + E + VD + + G+ + +DDG I + +S
Sbjct: 76 GNSEPVKLEKGDLVTL---GFME----GDVPVDARQFFETIDEGDIVLLDDGKIILQVES 128
Query: 689 VSADTLTCTIENGGMLGSGK 748
V + + GG+LG K
Sbjct: 129 VEGFRVKARVLEGGVLGPRK 148
>UniRef50_O06134 Cluster: Pyruvate kinase; n=29; Bacteria|Rep:
Pyruvate kinase - Mycobacterium tuberculosis
Length = 472
Score = 58.8 bits (136), Expect = 1e-07
Identities = 30/86 (34%), Positives = 46/86 (53%)
Frame = +3
Query: 258 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 437
R I+CT+GPA++ ++ ++E GM+VARMNFSHG ++ H R A + +
Sbjct: 3 RRGKIVCTLGPATQRDDLVRALVEAGMDVARMNFSHGDYDDHKVAYERVRVASDATGRAV 62
Query: 438 GSPFSLAIALDTKGPEIRTGLLEGAA 515
G + D +GP+IR G A
Sbjct: 63 G------VLADLQGPKIRLGRFASGA 82
Score = 56.8 bits (131), Expect = 5e-07
Identities = 25/88 (28%), Positives = 45/88 (51%)
Frame = +2
Query: 500 LGRGGSAEVELKKGETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISII 679
LGR S +GET+++T + G+ D + YK + G+R+ +DDG ++++
Sbjct: 75 LGRFASGATHWAEGETVRITVGACE--GSHDRVSTTYKRLAQDAVAGDRVLVDDGKVALV 132
Query: 680 CQSVSADTLTCTIENGGMLGSGKASTCP 763
+V D + CT+ GG + K + P
Sbjct: 133 VDAVEGDDVVCTVVEGGPVSDNKGISLP 160
>UniRef50_A0QNT2 Cluster: Pyruvate kinase; n=1; Mycobacterium
smegmatis str. MC2 155|Rep: Pyruvate kinase -
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Length = 477
Score = 58.4 bits (135), Expect = 2e-07
Identities = 29/80 (36%), Positives = 46/80 (57%)
Frame = +3
Query: 258 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 437
R + I+CT+GPA+ +VL ++++ GM+VAR+NFSH +H H+ RE +
Sbjct: 4 RRAKIVCTLGPATATSSVLTELVDAGMDVARLNFSHSTHAEHSALYGMVREIAAQRGRVV 63
Query: 438 GSPFSLAIALDTKGPEIRTG 497
G + D +GP+IR G
Sbjct: 64 G------VLADLQGPKIRLG 77
Score = 42.7 bits (96), Expect = 0.010
Identities = 22/88 (25%), Positives = 41/88 (46%)
Frame = +2
Query: 500 LGRGGSAEVELKKGETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISII 679
LG V GE + +T+ D G+ D + Y ++ V+ G+R+ +DDG + +
Sbjct: 76 LGCFADGPVVWATGEHVTITTEDCP--GDHDRVSTTYAGLSQDVRAGDRLLVDDGRVDLR 133
Query: 680 CQSVSADTLTCTIENGGMLGSGKASTCP 763
+V + C + +GG + K + P
Sbjct: 134 VVAVDGPDIRCEVVDGGPVSDHKGISLP 161
>UniRef50_Q9WY51 Cluster: Pyruvate kinase; n=3; Thermotogaceae|Rep:
Pyruvate kinase - Thermotoga maritima
Length = 466
Score = 58.4 bits (135), Expect = 2e-07
Identities = 31/84 (36%), Positives = 50/84 (59%)
Frame = +3
Query: 255 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 434
+R + I+CT+GP + + ++EKM++ G+NV R+N SHG + I ++ + K
Sbjct: 1 MRSTKIVCTVGPRTDSYEMIEKMIDLGVNVFRINTSHGDWNEQEQKILKIKDLRE----K 56
Query: 435 LGSPFSLAIALDTKGPEIRTGLLE 506
P +AI +D GP+IRTG LE
Sbjct: 57 KKKP--VAILIDLAGPKIRTGYLE 78
>UniRef50_Q0AHE3 Cluster: Pyruvate kinase; n=2;
Nitrosomonadaceae|Rep: Pyruvate kinase - Nitrosomonas
eutropha (strain C71)
Length = 483
Score = 57.6 bits (133), Expect = 3e-07
Identities = 33/84 (39%), Positives = 47/84 (55%), Gaps = 1/84 (1%)
Frame = +3
Query: 270 IICTIGPASRNVAVLEKMMETGM-NVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSP 446
IICT+GPA+ VL +++ GM +VAR N SHG H HA I+ R+ A+
Sbjct: 19 IICTLGPATDQPGVLARLIGAGMMDVARFNLSHGDHASHARRIQQVRQL-----AQQAGR 73
Query: 447 FSLAIALDTKGPEIRTGLLEGAAQ 518
F +A+ +D GP+ R G L A+
Sbjct: 74 F-IAVLMDLPGPKFRLGELSNGAR 96
>UniRef50_A7CAK5 Cluster: Pyruvate kinase; n=3; Ralstonia
pickettii|Rep: Pyruvate kinase - Ralstonia pickettii 12D
Length = 507
Score = 57.6 bits (133), Expect = 3e-07
Identities = 34/94 (36%), Positives = 51/94 (54%), Gaps = 1/94 (1%)
Frame = +3
Query: 258 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 437
R + I+ T+GPAS + + + + G +V R+NFSHGSHE H + R E A+
Sbjct: 20 RNTKILATLGPASSDKDTIRALFDAGADVFRLNFSHGSHEDHRKRYDTVRAVE----AET 75
Query: 438 GSPFSLAIALDTKGPEIRTG-LLEGAAQLKSN*R 536
G P + I D +GP++R G +G LK+ R
Sbjct: 76 GRP--IGILADMQGPKLRIGTFADGRVVLKNGDR 107
Score = 33.5 bits (73), Expect = 5.8
Identities = 18/88 (20%), Positives = 34/88 (38%)
Frame = +2
Query: 500 LGRGGSAEVELKKGETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISII 679
+G V LK G+ L G+ +++ + + PG + +DDG I +
Sbjct: 92 IGTFADGRVVLKNGDRFVLDRDP--TPGDVTRVHLPHPELYAATAPGQSLLLDDGKIRLA 149
Query: 680 CQSVSADTLTCTIENGGMLGSGKASTCP 763
++ + + +GG L K P
Sbjct: 150 VEAADPTAIVTRVVDGGPLSDRKGVNVP 177
>UniRef50_A6FYT4 Cluster: Pyruvate kinase; n=1; Plesiocystis
pacifica SIR-1|Rep: Pyruvate kinase - Plesiocystis
pacifica SIR-1
Length = 485
Score = 57.6 bits (133), Expect = 3e-07
Identities = 30/81 (37%), Positives = 49/81 (60%)
Frame = +3
Query: 255 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 434
+R + I+ T+GPAS + ++ +M+ G++ R+NFSHGSHE HA+ RE + S +
Sbjct: 6 LRRAKILGTLGPASNSDEMIGALMDAGLDAVRLNFSHGSHEDHAQVYGKVRE-QSSIRRR 64
Query: 435 LGSPFSLAIALDTKGPEIRTG 497
+A+ D +GP+IR G
Sbjct: 65 -----PVAVLGDLQGPKIRVG 80
Score = 36.7 bits (81), Expect = 0.63
Identities = 20/78 (25%), Positives = 35/78 (44%)
Frame = +2
Query: 530 LKKGETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLT 709
L+ GET+ + E + +DY + K G R+ +DDG + ++A +
Sbjct: 89 LETGETLVFLTDPTAEISQG-RVTIDYPTLDEEAKVGERVLMDDGELEARITEINAGEVH 147
Query: 710 CTIENGGMLGSGKASTCP 763
+ NGG+L + K P
Sbjct: 148 AEMLNGGVLKARKGVNLP 165
>UniRef50_A1WED1 Cluster: Pyruvate kinase; n=1; Verminephrobacter
eiseniae EF01-2|Rep: Pyruvate kinase - Verminephrobacter
eiseniae (strain EF01-2)
Length = 496
Score = 57.6 bits (133), Expect = 3e-07
Identities = 31/80 (38%), Positives = 45/80 (56%)
Frame = +3
Query: 258 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 437
R + I+ T+GPAS A+LE M+ G+NV R+NFSHG + H + R A +
Sbjct: 23 RATKIVATLGPASSEPALLEAMIRAGVNVVRLNFSHGKAQDHIDRAACVRAAAQR----- 77
Query: 438 GSPFSLAIALDTKGPEIRTG 497
+ +AI D +GP+IR G
Sbjct: 78 -AGHEVAIMADLQGPKIRVG 96
Score = 44.4 bits (100), Expect = 0.003
Identities = 25/83 (30%), Positives = 44/83 (53%)
Frame = +2
Query: 500 LGRGGSAEVELKKGETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISII 679
+G+ V L G L +S E G+ D + +DYK + + VK G+ + ++DGLI +
Sbjct: 95 VGKFAEGRVLLAPGAPFVLDASR-TEPGDIDGVGLDYKELPHDVKGGDLLLLNDGLIVLS 153
Query: 680 CQSVSADTLTCTIENGGMLGSGK 748
+V + + T++ GG L + K
Sbjct: 154 VDAVRGEQVHTTVKIGGELSNNK 176
>UniRef50_Q1ZJ78 Cluster: Pyruvate kinase; n=1; Psychromonas sp.
CNPT3|Rep: Pyruvate kinase - Psychromonas sp. CNPT3
Length = 485
Score = 57.2 bits (132), Expect = 4e-07
Identities = 28/74 (37%), Positives = 48/74 (64%)
Frame = +3
Query: 270 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 449
II T+GPAS++ ++ K++ G+N+ R+NFSHGS + H + C + + SA+LG
Sbjct: 6 IIATLGPASQSEDMIRKLILAGVNIVRLNFSHGSAQEHID----CAKLVRRISAELGK-- 59
Query: 450 SLAIALDTKGPEIR 491
+ + +D +GP+IR
Sbjct: 60 YVGVLVDLQGPKIR 73
>UniRef50_Q7P1G4 Cluster: Pyruvate kinase; n=4; Bacteria|Rep:
Pyruvate kinase - Chromobacterium violaceum
Length = 468
Score = 56.4 bits (130), Expect = 7e-07
Identities = 29/97 (29%), Positives = 53/97 (54%)
Frame = +3
Query: 252 VIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSA 431
++R + I+ T+GP+S + ++ +G+N+ R+N SHGSH+ H + R AEK+
Sbjct: 1 MLRNTKILATLGPSSSAPEKILELARSGVNIFRLNMSHGSHDDHRARLAAIRAAEKTLDR 60
Query: 432 KLGSPFSLAIALDTKGPEIRTGLLEGAAQLKSN*RRE 542
+G + +D +GP++R G +K+ R E
Sbjct: 61 PIG------VLVDLQGPKLRIGKFPQPTTVKTGDRYE 91
>UniRef50_Q1MPC8 Cluster: Pyruvate kinase; n=4;
Desulfovibrionaceae|Rep: Pyruvate kinase - Lawsonia
intracellularis (strain PHE/MN1-00)
Length = 471
Score = 56.0 bits (129), Expect = 1e-06
Identities = 31/84 (36%), Positives = 43/84 (51%)
Frame = +3
Query: 270 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 449
II TIGPAS + L ++++ G+++ R+NFSHG E I RE E +
Sbjct: 5 IIATIGPASNSKETLSQLIQAGVSIFRLNFSHGDSSAFIELISTIRELEHIHQ------I 58
Query: 450 SLAIALDTKGPEIRTGLLEGAAQL 521
+ I D GP+IR G L G L
Sbjct: 59 PITIMQDLSGPKIRIGALPGDVAL 82
>UniRef50_A1IEN3 Cluster: Pyruvate kinase; n=1; Candidatus
Desulfococcus oleovorans Hxd3|Rep: Pyruvate kinase -
Candidatus Desulfococcus oleovorans Hxd3
Length = 478
Score = 56.0 bits (129), Expect = 1e-06
Identities = 31/81 (38%), Positives = 46/81 (56%)
Frame = +3
Query: 270 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 449
+I TIGP SR+ AV+EK++ G+ + R+NFSH A+ I++ RE E+
Sbjct: 5 LIATIGPRSRDRAVIEKLVAVGVTIFRLNFSHAGPGDFADVIQSVREIEQQTGT------ 58
Query: 450 SLAIALDTKGPEIRTGLLEGA 512
L + D GP+IR G + GA
Sbjct: 59 ILTLMGDLSGPKIRIGEVAGA 79
>UniRef50_A0L5K6 Cluster: Pyruvate kinase; n=5; Proteobacteria|Rep:
Pyruvate kinase - Magnetococcus sp. (strain MC-1)
Length = 483
Score = 56.0 bits (129), Expect = 1e-06
Identities = 32/86 (37%), Positives = 49/86 (56%)
Frame = +3
Query: 255 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 434
IR + II T+GP + + ++ + TG++ R+NFSHGSHE H R E+ +
Sbjct: 4 IRRTKIIATLGPNASSRDFIKHLALTGVDTFRLNFSHGSHEDHRRRHGWIRSVEE----E 59
Query: 435 LGSPFSLAIALDTKGPEIRTGLLEGA 512
LG P L I +D +GP++R G E +
Sbjct: 60 LGRP--LGIMMDLQGPKLRIGTFENS 83
Score = 40.3 bits (90), Expect = 0.051
Identities = 21/88 (23%), Positives = 43/88 (48%)
Frame = +2
Query: 500 LGRGGSAEVELKKGETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISII 679
+G ++EVEL +G+ L + G+ + + + + + V++PG + ++DG I++
Sbjct: 77 IGTFENSEVELVRGQKFALYKEE--RTGDINGVTLPHNELFQVMRPGLELLLNDGRINLR 134
Query: 680 CQSVSADTLTCTIENGGMLGSGKASTCP 763
V + C + GG+L K P
Sbjct: 135 VMEVEDFGVCCEVRVGGILSDRKGLNVP 162
>UniRef50_Q8IJ37 Cluster: Pyruvate kinase; n=7; Plasmodium|Rep:
Pyruvate kinase - Plasmodium falciparum (isolate 3D7)
Length = 745
Score = 56.0 bits (129), Expect = 1e-06
Identities = 33/78 (42%), Positives = 41/78 (52%)
Frame = +3
Query: 273 ICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 452
I TIGPAS N LEK+ G++V R+NFSHG I + R EK Y +G
Sbjct: 102 IATIGPASENFEQLEKLYLNGIDVFRLNFSHGLKSIKKYIINSIRILEKKYDTTIG---- 157
Query: 453 LAIALDTKGPEIRTGLLE 506
I D +GP+IR G E
Sbjct: 158 --ILGDIQGPKIRIGEFE 173
>UniRef50_Q8ZNW0 Cluster: Pyruvate kinase II; n=173;
Proteobacteria|Rep: Pyruvate kinase II - Salmonella
typhimurium
Length = 480
Score = 56.0 bits (129), Expect = 1e-06
Identities = 35/79 (44%), Positives = 46/79 (58%)
Frame = +3
Query: 255 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 434
+R + I+ T+GPA+ LEK++ G NV RMNFSHGS E H RE +AK
Sbjct: 5 LRRTKIVTTLGPATDRDNNLEKVIAAGANVVRMNFSHGSPEDHKMRADKVRE----IAAK 60
Query: 435 LGSPFSLAIALDTKGPEIR 491
LG +AI D +GP+IR
Sbjct: 61 LGR--HVAILGDLQGPKIR 77
Score = 35.5 bits (78), Expect = 1.4
Identities = 19/76 (25%), Positives = 38/76 (50%)
Frame = +2
Query: 521 EVELKKGETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSAD 700
+V L G+ L ++ + +G+ + + +DYK + V PG+ + +DDG + + V
Sbjct: 85 KVFLNIGDKFLLDANLGKGEGDKEKVGIDYKGLPADVVPGDILLLDDGRVQLKVLEVQGM 144
Query: 701 TLTCTIENGGMLGSGK 748
+ + GG L + K
Sbjct: 145 KVFTEVTVGGPLSNNK 160
>UniRef50_UPI0000DB6F59 Cluster: PREDICTED: similar to Pyruvate
kinase CG7070-PB, isoform B; n=1; Apis mellifera|Rep:
PREDICTED: similar to Pyruvate kinase CG7070-PB, isoform
B - Apis mellifera
Length = 538
Score = 55.6 bits (128), Expect = 1e-06
Identities = 24/84 (28%), Positives = 47/84 (55%)
Frame = +3
Query: 258 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 437
RL+ I+ T+G + + + +M G N+ R+N +H + ++H T+++ R+A +
Sbjct: 39 RLTRIMVTLGRRNSHPEAVVSIMMAGANIVRLNMAHETDKWHTATVQSVRKAGNTMYEFT 98
Query: 438 GSPFSLAIALDTKGPEIRTGLLEG 509
+ L +A++ +GPEIR G G
Sbjct: 99 SEIYPLGVAINLQGPEIRAGAFRG 122
Score = 53.2 bits (122), Expect = 7e-06
Identities = 24/75 (32%), Positives = 43/75 (57%), Gaps = 1/75 (1%)
Frame = +2
Query: 527 ELKKGETIKLTSSDYQEK-GNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADT 703
+LK+G+ +KL + D ++ G A+ +V Y N+ + + G+RI ID G + + +
Sbjct: 131 KLKEGKMVKLVTQDIAKRAGRANCFWVSYPNLPKICQVGDRILIDRGAVLLQVTCIHEQA 190
Query: 704 LTCTIENGGMLGSGK 748
+TC I GG++ GK
Sbjct: 191 ITCKIIKGGIVKDGK 205
>UniRef50_Q8G5M1 Cluster: Pyruvate kinase; n=23;
Actinobacteridae|Rep: Pyruvate kinase - Bifidobacterium
longum
Length = 509
Score = 55.6 bits (128), Expect = 1e-06
Identities = 30/81 (37%), Positives = 50/81 (61%)
Frame = +3
Query: 255 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 434
+R + I+ TIGP++ + L K++E GM+VAR+N SHG+ E H + N R+A ++
Sbjct: 30 MRKAKIVDTIGPSTEDYDNLLKLVEAGMDVARLNRSHGTPEDHLKVYNNVRKASEATGR- 88
Query: 435 LGSPFSLAIALDTKGPEIRTG 497
++A +D +GP+IR G
Sbjct: 89 -----NVAALVDLQGPKIRCG 104
Score = 34.7 bits (76), Expect = 2.5
Identities = 20/84 (23%), Positives = 37/84 (44%)
Frame = +2
Query: 512 GSAEVELKKGETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSV 691
G +V+L+ G+ +T+ D + G+ +K + PG+ I IDDG + + V
Sbjct: 112 GEDKVQLQLGQEFVITTDDVE--GDEHITSTTFKGLPGDCHPGDPILIDDGKVRLEVTKV 169
Query: 692 SADTLTCTIENGGMLGSGKASTCP 763
+ + + G + S K P
Sbjct: 170 EGNNVYTKVVVAGPVSSHKGINLP 193
>UniRef50_A6LH43 Cluster: Pyruvate kinase; n=2; Parabacteroides|Rep:
Pyruvate kinase - Parabacteroides distasonis (strain
ATCC 8503 / DSM 20701 / NCTC11152)
Length = 485
Score = 54.0 bits (124), Expect = 4e-06
Identities = 30/80 (37%), Positives = 41/80 (51%)
Frame = +2
Query: 524 VELKKGETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADT 703
+ K GE +K+ + QE + D I V YKN N + G+ I IDDG + + S D
Sbjct: 80 IPFKTGEIVKVIGNPDQETSH-DCICVSYKNFVNDLAIGSDILIDDGDLEMKVTGKSGDC 138
Query: 704 LTCTIENGGMLGSGKASTCP 763
L C I+N LGS K+ P
Sbjct: 139 LLCEIQNDATLGSRKSVNVP 158
Score = 44.4 bits (100), Expect = 0.003
Identities = 26/81 (32%), Positives = 44/81 (54%)
Frame = +3
Query: 252 VIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSA 431
+++ + I+ T+ +VA +E + + GMNV R+N +H E + N R + S
Sbjct: 1 MLKHTKIVATVSDQRCDVAFVEALYKAGMNVVRLNTAHMMEEGLTRVVNNVR----TVSD 56
Query: 432 KLGSPFSLAIALDTKGPEIRT 494
++G I +DTKGPE+RT
Sbjct: 57 RIG------ILMDTKGPEVRT 71
>UniRef50_A7QH42 Cluster: Chromosome chr3 scaffold_95, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr3 scaffold_95, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 573
Score = 52.8 bits (121), Expect = 9e-06
Identities = 25/78 (32%), Positives = 45/78 (57%)
Frame = +3
Query: 255 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 434
+R + ++CTIGPA + LE + +GMNVAR+N H + E+H + IR + +
Sbjct: 87 MRKTKLVCTIGPACCLLEDLENLASSGMNVARLNMCHNTWEWHRDVIRKIKRLNEE---- 142
Query: 435 LGSPFSLAIALDTKGPEI 488
+ +++ +DT+G +I
Sbjct: 143 --KGYCVSVMIDTEGGQI 158
>UniRef50_Q9PF54 Cluster: Pyruvate kinase; n=11;
Xanthomonadaceae|Rep: Pyruvate kinase - Xylella
fastidiosa
Length = 501
Score = 52.0 bits (119), Expect = 2e-05
Identities = 33/98 (33%), Positives = 49/98 (50%), Gaps = 1/98 (1%)
Frame = +3
Query: 258 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 437
R + I+ T+GPA+ VL+ + + G+NV R+NFSHG A R A ++
Sbjct: 19 RRTRILATLGPATDPPGVLDALFKAGVNVVRLNFSHGDASDQARRAAEVRAAAAHVGVEI 78
Query: 438 GSPFSLAIALDTKGPEIRTG-LLEGAAQLKSN*RRERL 548
G I D GP+IR G EG +L ++ R + L
Sbjct: 79 G------ILADLPGPKIRIGRFTEGKVRLVADARFDLL 110
>UniRef50_Q0PQH4 Cluster: Pyruvate kinase; n=1; Endoriftia
persephone 'Hot96_1+Hot96_2'|Rep: Pyruvate kinase -
Endoriftia persephone 'Hot96_1+Hot96_2'
Length = 246
Score = 52.0 bits (119), Expect = 2e-05
Identities = 24/80 (30%), Positives = 45/80 (56%)
Frame = +3
Query: 258 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 437
R + I+ T+GPA+ + V++K++ G++V R+N SH H+ E R+ ++ ++
Sbjct: 36 RRTKIVATLGPATDDPKVMDKLIHAGVDVVRLNLSHDPHDQQRERAERIRDRSRASGRQV 95
Query: 438 GSPFSLAIALDTKGPEIRTG 497
G + D +GP+IR G
Sbjct: 96 G------VLCDLQGPKIRIG 109
>UniRef50_A4APL1 Cluster: Pyruvate kinase; n=15; Bacteroidetes|Rep:
Pyruvate kinase - Flavobacteriales bacterium HTCC2170
Length = 480
Score = 52.0 bits (119), Expect = 2e-05
Identities = 26/85 (30%), Positives = 49/85 (57%)
Frame = +3
Query: 255 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 434
I+ + I+ T+GPA+ V+ M++ G++V R+NFSH +E ++ RE + +
Sbjct: 4 IKKTKIVATLGPATSKKEVIIDMIKAGVDVFRINFSHADYEDVTARVKMIREVNEEIDS- 62
Query: 435 LGSPFSLAIALDTKGPEIRTGLLEG 509
++AI D +GP++R G++ G
Sbjct: 63 -----NIAILGDLQGPKLRVGVMSG 82
Score = 43.6 bits (98), Expect = 0.005
Identities = 26/84 (30%), Positives = 41/84 (48%), Gaps = 1/84 (1%)
Frame = +2
Query: 515 SAEVELKKGETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDG-LISIICQSV 691
S EV + G+ I + + E GN++ +Y++Y V PG RI +DDG L+ + +
Sbjct: 81 SGEVVVTPGDEIDFVTGEPFE-GNSERVYMNYAAFPKDVNPGERILLDDGKLMFEVVSTN 139
Query: 692 SADTLTCTIENGGMLGSGKASTCP 763
D + + GG L S K P
Sbjct: 140 KKDKVRAKVIQGGPLKSKKGVNLP 163
>UniRef50_P46614 Cluster: Pyruvate kinase; n=1; Candida
albicans|Rep: Pyruvate kinase - Candida albicans (Yeast)
Length = 92
Score = 51.6 bits (118), Expect = 2e-05
Identities = 28/72 (38%), Positives = 39/72 (54%), Gaps = 1/72 (1%)
Frame = +2
Query: 542 ETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSV-SADTLTCTI 718
E I T Y+ K + + +DYKNIT V+ PG I++DDG++S SV TL
Sbjct: 8 EMIFTTDDAYKTKCDDKVMIIDYKNITKVIAPGKIIYVDDGVLSFEVISVDDQQTLKVRS 67
Query: 719 ENGGMLGSGKAS 754
N GM+ S K +
Sbjct: 68 LNAGMISSHKTA 79
>UniRef50_A2BLH1 Cluster: Pyruvate kinase; n=1; Hyperthermus
butylicus DSM 5456|Rep: Pyruvate kinase - Hyperthermus
butylicus (strain DSM 5456 / JCM 9403)
Length = 466
Score = 51.2 bits (117), Expect = 3e-05
Identities = 33/91 (36%), Positives = 49/91 (53%)
Frame = +3
Query: 270 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 449
II +IGP+S + V+ ++ E G++ R+NF+HG E REAE+ K G P
Sbjct: 8 IIASIGPSSGSPEVILRLAELGVSGFRINFAHGEPSLWREWAEYVREAER----KTGRP- 62
Query: 450 SLAIALDTKGPEIRTGLLEGAAQLKSN*RRE 542
LA+ D GP IR G ++ +L + R E
Sbjct: 63 -LALIGDLVGPSIRLGRVKNPIKLNAGDRAE 92
>UniRef50_P78031 Cluster: Pyruvate kinase; n=6; Mycoplasma|Rep:
Pyruvate kinase - Mycoplasma pneumoniae
Length = 508
Score = 50.8 bits (116), Expect = 4e-05
Identities = 29/62 (46%), Positives = 38/62 (61%)
Frame = +3
Query: 306 AVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPE 485
A +E +++ G+ V R+NFSHG+HE A I+ R+ K KL P S I LDT GPE
Sbjct: 42 ANIENIIKNGVTVIRLNFSHGNHEEQAVRIKIVRDVAK----KLNLPVS--IMLDTNGPE 95
Query: 486 IR 491
IR
Sbjct: 96 IR 97
>UniRef50_O05118 Cluster: Pyruvate kinase; n=44; Proteobacteria|Rep:
Pyruvate kinase - Methylobacterium extorquens
(Protomonas extorquens)
Length = 483
Score = 50.8 bits (116), Expect = 4e-05
Identities = 30/91 (32%), Positives = 46/91 (50%)
Frame = +3
Query: 258 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 437
R + I+ T+GPAS ++EK+ G +V R+N SH + E E I R E+ +
Sbjct: 10 RRTKIVATLGPASDTPEMIEKLFHAGADVFRINMSHLAREKLPERIEVIRTIEREGKRPI 69
Query: 438 GSPFSLAIALDTKGPEIRTGLLEGAAQLKSN 530
G I +D +GP++R G G A + N
Sbjct: 70 G------ILVDLQGPKLRLGTFVGDAAVLEN 94
>UniRef50_Q7QVW2 Cluster: Pyruvate kinase; n=1; Giardia lamblia ATCC
50803|Rep: Pyruvate kinase - Giardia lamblia ATCC 50803
Length = 553
Score = 50.4 bits (115), Expect = 5e-05
Identities = 26/74 (35%), Positives = 44/74 (59%)
Frame = +3
Query: 270 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 449
I CT+GP+S NV V+ M+ G ++ R+NFSHG+ + H + ++A + K
Sbjct: 42 ICCTLGPSSFNVEVIAGMIRAGADIIRINFSHGNTDDHTQIFHKVQQA-MQLTGK----- 95
Query: 450 SLAIALDTKGPEIR 491
++AI D +GP++R
Sbjct: 96 TVAIMGDIQGPKLR 109
>UniRef50_Q6L281 Cluster: Pyruvate kinase; n=2;
Thermoplasmatales|Rep: Pyruvate kinase - Picrophilus
torridus
Length = 555
Score = 50.4 bits (115), Expect = 5e-05
Identities = 25/76 (32%), Positives = 43/76 (56%)
Frame = +3
Query: 270 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 449
+I TIGPAS ++ +++KM G++ R+N +H + Y + + + KS +G
Sbjct: 6 LIATIGPASESMEIIKKMANLGLSCIRINTAHIENGYITKVAKMVDDVNKSEGTYIG--- 62
Query: 450 SLAIALDTKGPEIRTG 497
+ +D KGPE+RTG
Sbjct: 63 ---LMVDLKGPELRTG 75
>UniRef50_A3ZTM3 Cluster: Pyruvate kinase; n=1; Blastopirellula
marina DSM 3645|Rep: Pyruvate kinase - Blastopirellula
marina DSM 3645
Length = 490
Score = 49.6 bits (113), Expect = 8e-05
Identities = 28/78 (35%), Positives = 42/78 (53%)
Frame = +3
Query: 270 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 449
I+ T+GPA +LE+M+ G++V R+N +HG + H+ RE S +L P
Sbjct: 15 IVATVGPACNTPEMLEQMILAGVDVFRLNLAHGELDEHSRVATTIRE----ISERLKRP- 69
Query: 450 SLAIALDTKGPEIRTGLL 503
+A D GP+IR G L
Sbjct: 70 -VATLADLSGPKIRLGTL 86
Score = 34.7 bits (76), Expect = 2.5
Identities = 15/53 (28%), Positives = 30/53 (56%)
Frame = +2
Query: 605 DYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSGKASTCP 763
+Y+ + + VK G+ + + DG I++ + D++TC + GG+L S + P
Sbjct: 116 NYEPLIDEVKVGDNVMLADGTITMEVVEKTEDSVTCVVVAGGILRSRQGINLP 168
>UniRef50_A3ALA5 Cluster: Pyruvate kinase; n=3; Oryza sativa|Rep:
Pyruvate kinase - Oryza sativa subsp. japonica (Rice)
Length = 548
Score = 48.8 bits (111), Expect = 1e-04
Identities = 27/91 (29%), Positives = 46/91 (50%)
Frame = +3
Query: 255 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 434
+R + ++CT+GPA V L + GM VAR+N HG +H +R R +
Sbjct: 62 LRKTKLVCTVGPAC--VGALPALARGGMGVARVNLCHGGRGWHRAVMREVRRLNEE---- 115
Query: 435 LGSPFSLAIALDTKGPEIRTGLLEGAAQLKS 527
F +++ +DT+G ++ GAA +K+
Sbjct: 116 --EGFCVSLMVDTEGSQLLVADHGGAASVKA 144
>UniRef50_A3DMY9 Cluster: Pyruvate kinase; n=1; Staphylothermus
marinus F1|Rep: Pyruvate kinase - Staphylothermus
marinus (strain ATCC 43588 / DSM 3639 / F1)
Length = 469
Score = 48.8 bits (111), Expect = 1e-04
Identities = 27/78 (34%), Positives = 44/78 (56%)
Frame = +3
Query: 270 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 449
II TIGP+S VL ++++ G++ R+NFSHG+ E ++ RE + Y +
Sbjct: 6 IITTIGPSSGKYEVLSRLIQEGVDGFRINFSHGNPHEWDEWVKMVRELAEKYERE----- 60
Query: 450 SLAIALDTKGPEIRTGLL 503
++I D GP++R G L
Sbjct: 61 -ISIMGDLPGPQVRIGEL 77
>UniRef50_Q5ZZ75 Cluster: Pyruvate kinase II; n=4; Legionella
pneumophila|Rep: Pyruvate kinase II - Legionella
pneumophila subsp. pneumophila (strain Philadelphia 1
/ATCC 33152 / DSM 7513)
Length = 474
Score = 48.4 bits (110), Expect = 2e-04
Identities = 28/82 (34%), Positives = 46/82 (56%)
Frame = +3
Query: 252 VIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSA 431
++R + I+ T+GPAS+ +L M+ G+NV R+NFSH + I R+ +
Sbjct: 1 MLRRTKIVATLGPASKEPEILRSMLAAGVNVVRINFSHADSS-ALQLIALVRK----IAD 55
Query: 432 KLGSPFSLAIALDTKGPEIRTG 497
+L P +A+ D +GP+IR G
Sbjct: 56 ELNHP--VAVMADLQGPKIRVG 75
Score = 41.9 bits (94), Expect = 0.017
Identities = 21/79 (26%), Positives = 38/79 (48%)
Frame = +2
Query: 500 LGRGGSAEVELKKGETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISII 679
+GR + + L G+ L G+ + + V Y N+ N + G+ + I+DGLI +
Sbjct: 74 VGRFQNKSITLIDGQNFTLDCMAPDTLGDINGVSVAYPNLANELSIGDHLLINDGLIELE 133
Query: 680 CQSVSADTLTCTIENGGML 736
+S + C + GG+L
Sbjct: 134 VIEISGSKIHCKVVEGGVL 152
>UniRef50_Q07637 Cluster: Pyruvate kinase; n=44;
Streptococcaceae|Rep: Pyruvate kinase - Lactococcus
lactis subsp. lactis (Streptococcus lactis)
Length = 502
Score = 47.6 bits (108), Expect = 3e-04
Identities = 29/75 (38%), Positives = 38/75 (50%)
Frame = +3
Query: 291 ASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALD 470
+++N+A L +E G NV R NFSHG H + AE+ K+G LD
Sbjct: 38 SAKNIAAL---IEEGANVFRFNFSHGDHPEQGARMATVHRAEEIAGHKVG------FLLD 88
Query: 471 TKGPEIRTGLLEGAA 515
TKGPE+RT L A
Sbjct: 89 TKGPEMRTELFADGA 103
>UniRef50_A5JEK8 Cluster: Pyruvate kinase; n=1; Nosema bombycis|Rep:
Pyruvate kinase - Nosema bombycis
Length = 441
Score = 46.4 bits (105), Expect = 8e-04
Identities = 26/82 (31%), Positives = 44/82 (53%)
Frame = +3
Query: 261 LSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLG 440
++ II T+ S + L ++ G+++ R+N SHG+ H +I N R+ K ++G
Sbjct: 5 MTKIIVTVSSVSDDEETLTNFLKEGVHIFRINLSHGTSYQHEHSILNIRKCAK----EMG 60
Query: 441 SPFSLAIALDTKGPEIRTGLLE 506
I LDT+GPE+R + E
Sbjct: 61 --IVPVICLDTRGPEVRIEIAE 80
>UniRef50_O51323 Cluster: Pyruvate kinase; n=5; cellular
organisms|Rep: Pyruvate kinase - Borrelia burgdorferi
(Lyme disease spirochete)
Length = 477
Score = 46.4 bits (105), Expect = 8e-04
Identities = 27/92 (29%), Positives = 47/92 (51%)
Frame = +3
Query: 252 VIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSA 431
+ +L+ I+ TI ++ + + G+NV R+N +H SHE + I N R+
Sbjct: 2 ISKLTKIVATISDLRCEPEHIKDLHDAGVNVIRLNTAHQSHEDTIKVIDNVRKISN---- 57
Query: 432 KLGSPFSLAIALDTKGPEIRTGLLEGAAQLKS 527
+A+ +DTKGPE+RT +E +K+
Sbjct: 58 ------KIALMIDTKGPEVRTANIENPIIVKT 83
Score = 40.3 bits (90), Expect = 0.051
Identities = 21/78 (26%), Positives = 38/78 (48%)
Frame = +2
Query: 530 LKKGETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLT 709
+K G+ + +++S E N T +Y V G+++ IDDG + + + D L
Sbjct: 81 VKTGDKVIISTSPINEPNNFQT---NYDGFVKEVPQGSKVLIDDGELEMTVVAKLPDRLI 137
Query: 710 CTIENGGMLGSGKASTCP 763
C I+N G + + K+ P
Sbjct: 138 CEIKNDGQIKNKKSINTP 155
>UniRef50_Q64MR8 Cluster: Pyruvate kinase; n=6; Bacteroides|Rep:
Pyruvate kinase - Bacteroides fragilis
Length = 485
Score = 46.0 bits (104), Expect = 0.001
Identities = 26/81 (32%), Positives = 42/81 (51%)
Frame = +3
Query: 252 VIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSA 431
+++ + I+ +I +V ++++ + GMNV RMN +H S E I N R
Sbjct: 2 LLKQTKIVASISDRRCDVDFIKELFDAGMNVVRMNTAHASREGFEALIANVRAVSN---- 57
Query: 432 KLGSPFSLAIALDTKGPEIRT 494
+AI +DTKGPE+RT
Sbjct: 58 ------RIAILMDTKGPEVRT 72
Score = 40.3 bits (90), Expect = 0.051
Identities = 22/75 (29%), Positives = 35/75 (46%)
Frame = +2
Query: 539 GETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTI 718
GE +K+ D + + I V Y N + + G I IDDG + + + + L C +
Sbjct: 84 GEKVKIVG-DPDRETTRECIAVSYPNFVHDLNVGGTILIDDGDLELRVIDKTTEYLLCEV 142
Query: 719 ENGGMLGSGKASTCP 763
+N LGS K+ P
Sbjct: 143 QNEATLGSRKSVNVP 157
>UniRef50_UPI00006CE5D4 Cluster: pyruvate kinase family protein;
n=1; Tetrahymena thermophila SB210|Rep: pyruvate kinase
family protein - Tetrahymena thermophila SB210
Length = 495
Score = 45.2 bits (102), Expect = 0.002
Identities = 17/37 (45%), Positives = 29/37 (78%)
Frame = +3
Query: 258 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHG 368
R + I+CT+GP S +V ++ K++++GMNVAR+ + HG
Sbjct: 22 RKTKIVCTLGPQSSSVEMICKLLDSGMNVARITYCHG 58
>UniRef50_P32044 Cluster: Pyruvate kinase; n=2; Thermoplasma|Rep:
Pyruvate kinase - Thermoplasma acidophilum
Length = 544
Score = 45.2 bits (102), Expect = 0.002
Identities = 24/80 (30%), Positives = 45/80 (56%)
Frame = +3
Query: 270 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 449
I+ TIGPAS + ++++M++ G+++ R+N +H + + + +S + +G
Sbjct: 5 IVATIGPASSSPEIMKQMIDNGLSLVRINSAHAD----IKDVSKITQMVRSINRDVG--- 57
Query: 450 SLAIALDTKGPEIRTGLLEG 509
I +D KGPE+RTG G
Sbjct: 58 ---IMIDLKGPELRTGEFAG 74
>UniRef50_A7APT5 Cluster: Pyruvate kinase family protein; n=1;
Babesia bovis|Rep: Pyruvate kinase family protein -
Babesia bovis
Length = 693
Score = 44.8 bits (101), Expect = 0.002
Identities = 25/79 (31%), Positives = 41/79 (51%), Gaps = 4/79 (5%)
Frame = +3
Query: 273 ICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 452
+ T+GP++ L +ME G ++ R+NFSHG+ + R R+ E S+ GS
Sbjct: 115 VSTLGPSTCTADSLRSIMEAGTDIYRLNFSHGTRLFKLRLTRMIRQLELVRSSGEGSDSF 174
Query: 453 L----AIALDTKGPEIRTG 497
+ I D +GP++R G
Sbjct: 175 MVSPKGILGDIQGPKLRIG 193
Score = 43.6 bits (98), Expect = 0.005
Identities = 27/82 (32%), Positives = 43/82 (52%), Gaps = 2/82 (2%)
Frame = +2
Query: 524 VELKKGETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSAD- 700
VELKKG+ K T + KG+ + ++ +I + GN I +DDG +++ SV D
Sbjct: 214 VELKKGD--KFTFDTHDVKGSQTRVRFNFPDILRDLNVGNTIAMDDGNLNLEVISVDRDA 271
Query: 701 -TLTCTIENGGMLGSGKASTCP 763
++T + N G+L S K P
Sbjct: 272 PSVTAVVLNDGVLSSRKGFAVP 293
>UniRef50_Q8EWX2 Cluster: Pyruvate kinase; n=1; Mycoplasma
penetrans|Rep: Pyruvate kinase - Mycoplasma penetrans
Length = 498
Score = 44.4 bits (100), Expect = 0.003
Identities = 27/70 (38%), Positives = 36/70 (51%)
Frame = +3
Query: 282 IGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAI 461
I A +N+A L + G+NV R NFSHG +E + RE K +++
Sbjct: 36 IETAKKNLAAL---FDAGVNVVRFNFSHGDYEEQTIRLNLVREVAKEKGV------NIST 86
Query: 462 ALDTKGPEIR 491
LDTKGPEIR
Sbjct: 87 MLDTKGPEIR 96
>UniRef50_A4ARB8 Cluster: Pyruvate kinase; n=1; Flavobacteriales
bacterium HTCC2170|Rep: Pyruvate kinase -
Flavobacteriales bacterium HTCC2170
Length = 624
Score = 43.6 bits (98), Expect = 0.005
Identities = 28/86 (32%), Positives = 47/86 (54%), Gaps = 2/86 (2%)
Frame = +3
Query: 258 RLSGIICTI-GPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 434
R + I+ T+ A+ ++ + K++ GMN AR+N +H + E + I N + A K K
Sbjct: 131 RFTRIMVTLPNTAAEDLGFIRKLLANGMNCARINCAHDTPEDWLKMIDNLKIASKRQRKK 190
Query: 435 LGSPFSLAIALDTKGPEIRTG-LLEG 509
IA+D GP++RTG ++EG
Sbjct: 191 ------CKIAMDLSGPKLRTGPMVEG 210
>UniRef50_A6LTB0 Cluster: Pyruvate kinase; n=1; Clostridium
beijerinckii NCIMB 8052|Rep: Pyruvate kinase -
Clostridium beijerinckii NCIMB 8052
Length = 340
Score = 42.7 bits (96), Expect = 0.010
Identities = 20/56 (35%), Positives = 33/56 (58%)
Frame = +3
Query: 270 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 437
II T+GP ++ AVL+ ++E+G+N R NF HGS E E ++ ++ + L
Sbjct: 3 IIGTVGPNVKDRAVLKGIIESGVNALRFNFIHGSAEEFLEFLKMAKDIKSDIQVML 58
>UniRef50_Q8MR79 Cluster: Pyruvate kinase; n=3; Sophophora|Rep:
Pyruvate kinase - Drosophila melanogaster (Fruit fly)
Length = 659
Score = 42.7 bits (96), Expect = 0.010
Identities = 27/76 (35%), Positives = 42/76 (55%), Gaps = 1/76 (1%)
Frame = +2
Query: 512 GSAEVELKKGETIKLT-SSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQS 688
G VEL +G+ + LT Y ++ NAD IYV+ + + V P + I I + I ++ +S
Sbjct: 239 GKKCVELVQGQKVILTVDRQYSDRSNADVIYVNARFLIVDVHPLDFILIGED-IQLMVRS 297
Query: 689 VSADTLTCTIENGGML 736
+ AD L + GGML
Sbjct: 298 IHADHLKGCVARGGML 313
>UniRef50_Q4N603 Cluster: Pyruvate kinase; n=2; Theileria|Rep:
Pyruvate kinase - Theileria parva
Length = 699
Score = 41.5 bits (93), Expect = 0.022
Identities = 27/88 (30%), Positives = 47/88 (53%), Gaps = 6/88 (6%)
Frame = +3
Query: 252 VIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSH-EYH--AETIR--NCREAE 416
++ L+ + T+GPA+ N ++ + + G++V R+NFSH S H ++TIR E
Sbjct: 115 ILTLTKQVATLGPATNNAESIKSLFDAGVDVFRLNFSHDSRLSKHLVSKTIRQLEINEPP 174
Query: 417 KSYSAKLGSPFS-LAIALDTKGPEIRTG 497
K+Y +I D +GP++R G
Sbjct: 175 KNYPFNGDHVVEHKSILGDIQGPKLRIG 202
>UniRef50_A4VPY3 Cluster: Pyruvate kinase; n=1; Pseudomonas stutzeri
A1501|Rep: Pyruvate kinase - Pseudomonas stutzeri
(strain A1501)
Length = 625
Score = 41.1 bits (92), Expect = 0.029
Identities = 26/78 (33%), Positives = 43/78 (55%)
Frame = +3
Query: 291 ASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALD 470
A+ N ++E +++ GM+ AR+N +H + I + R AEK+ LG +ALD
Sbjct: 150 AAHNRDLIEALIKEGMDCARINCAHDDPDSWRAMIEHVRAAEKA----LGR--ECKVALD 203
Query: 471 TKGPEIRTGLLEGAAQLK 524
GP++RTG + A +K
Sbjct: 204 LAGPKLRTGPIATAPGVK 221
>UniRef50_Q4IUP8 Cluster: Pyruvate kinase; n=1; Azotobacter
vinelandii AvOP|Rep: Pyruvate kinase - Azotobacter
vinelandii AvOP
Length = 165
Score = 40.7 bits (91), Expect = 0.038
Identities = 18/51 (35%), Positives = 29/51 (56%)
Frame = +3
Query: 258 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCRE 410
R + I+ T+G A+ +E +++ G++V R+NFSHG E H RE
Sbjct: 3 RRTKIVATLGSATETPEAIEGLVKAGVDVVRLNFSHGKAEEHQARATLVRE 53
>UniRef50_A1RX09 Cluster: Pyruvate kinase; n=1; Thermofilum pendens
Hrk 5|Rep: Pyruvate kinase - Thermofilum pendens (strain
Hrk 5)
Length = 464
Score = 40.3 bits (90), Expect = 0.051
Identities = 22/76 (28%), Positives = 37/76 (48%)
Frame = +3
Query: 270 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 449
++ T+GP+S + +++M+ G+N R+NFSH + E + R E
Sbjct: 6 LVATLGPSSWSEETMKRMVAEGVNAFRLNFSHVDYARFEELAKQVRRLETPLR------- 58
Query: 450 SLAIALDTKGPEIRTG 497
L + D +GP IR G
Sbjct: 59 PLTLIADLQGPVIRLG 74
>UniRef50_Q2JJ60 Cluster: Pyruvate kinase; n=5; Bacteria|Rep:
Pyruvate kinase - Synechococcus sp. (strain
JA-2-3B'a(2-13)) (Cyanobacteria bacteriumYellowstone
B-Prime)
Length = 476
Score = 39.9 bits (89), Expect = 0.067
Identities = 26/81 (32%), Positives = 42/81 (51%), Gaps = 1/81 (1%)
Frame = +3
Query: 258 RLSGIICTI-GPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 434
R + I+ T+ A+ +L +++E GMNVAR+N +H + + + R+AE +
Sbjct: 118 RRARIMVTLPSEAAEQPELLLQLLERGMNVARINCAHDEPSVWEKMVAHLRQAEAQTQRR 177
Query: 435 LGSPFSLAIALDTKGPEIRTG 497
I LD GP+IRTG
Sbjct: 178 ------CKILLDLAGPKIRTG 192
>UniRef50_A1U5Q4 Cluster: Pyruvate kinase; n=2; Marinobacter
aquaeolei VT8|Rep: Pyruvate kinase - Marinobacter
aquaeolei (strain ATCC 700491 / DSM 11845 /
VT8)(Marinobacter hydrocarbonoclasticus (strain DSM
11845))
Length = 626
Score = 39.9 bits (89), Expect = 0.067
Identities = 20/72 (27%), Positives = 40/72 (55%)
Frame = +3
Query: 291 ASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALD 470
++++ +++ +++ GMN R+N +H E E I N + A++ + S + +D
Sbjct: 154 SAQDPSIIRDLLKAGMNCMRINCAHDDPETWLEMINNLQTAKEEFGQ------SCQVFMD 207
Query: 471 TKGPEIRTGLLE 506
GP+IRTG +E
Sbjct: 208 LGGPKIRTGEIE 219
>UniRef50_A7PC98 Cluster: Chromosome chr2 scaffold_11, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr2 scaffold_11, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 475
Score = 39.9 bits (89), Expect = 0.067
Identities = 22/55 (40%), Positives = 30/55 (54%)
Frame = +3
Query: 360 SHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGAAQLK 524
SHG H H +TI +E + K+ +AI LDTKGPE+R+G + LK
Sbjct: 2 SHGDHASHKKTIDLVKEYNAQFEDKV-----IAIMLDTKGPEVRSGDVPKPIMLK 51
>UniRef50_A7QTW5 Cluster: Chromosome undetermined scaffold_171,
whole genome shotgun sequence; n=1; Vitis vinifera|Rep:
Chromosome undetermined scaffold_171, whole genome
shotgun sequence - Vitis vinifera (Grape)
Length = 622
Score = 39.1 bits (87), Expect = 0.12
Identities = 24/81 (29%), Positives = 43/81 (53%), Gaps = 1/81 (1%)
Frame = +3
Query: 258 RLSGIICTIGP-ASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 434
R + I+ T+G + N ++ ++++G + R+N +HG+ +E IR R + S
Sbjct: 258 RTAHIMVTVGQEVTENETLITDILKSGATIIRINCAHGNPSIWSEIIRRVRRS----SQM 313
Query: 435 LGSPFSLAIALDTKGPEIRTG 497
L P I +D GP++RTG
Sbjct: 314 LEKP--CRILMDLAGPKLRTG 332
>UniRef50_Q5KVI2 Cluster: Pyruvate kinase; n=2; Geobacillus|Rep:
Pyruvate kinase - Geobacillus kaustophilus
Length = 660
Score = 37.5 bits (83), Expect = 0.36
Identities = 21/65 (32%), Positives = 36/65 (55%)
Frame = +3
Query: 309 VLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEI 488
++E+++ GM++AR+N ++GS E + R+AEK +L I +D GP+I
Sbjct: 189 LIERLLLYGMDIARINCAYGSPETWEALVAIIRQAEKQLEQQLQGR-RCRIYMDLPGPKI 247
Query: 489 RTGLL 503
R L
Sbjct: 248 RVDRL 252
>UniRef50_A3PTF7 Cluster: Pyruvate kinase; n=5; Mycobacterium|Rep:
Pyruvate kinase - Mycobacterium sp. (strain JLS)
Length = 615
Score = 35.9 bits (79), Expect = 1.1
Identities = 24/81 (29%), Positives = 41/81 (50%), Gaps = 1/81 (1%)
Frame = +3
Query: 258 RLSGIICTI-GPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 434
R + I+ T+ A+ + ++ ++ GMNVAR+N +H E + R A +S K
Sbjct: 138 RATRIMVTLPSSAATDPDLVRDLIARGMNVARINCAHDDAEAWTAMAGHVRRAAESTGRK 197
Query: 435 LGSPFSLAIALDTKGPEIRTG 497
+A+D GP++RTG
Sbjct: 198 ------CLVAMDLAGPKLRTG 212
>UniRef50_Q9PQV7 Cluster: Pyruvate kinase; n=1; Ureaplasma
parvum|Rep: Pyruvate kinase - Ureaplasma parvum
(Ureaplasma urealyticum biotype 1)
Length = 474
Score = 35.5 bits (78), Expect = 1.4
Identities = 19/60 (31%), Positives = 31/60 (51%)
Frame = +3
Query: 312 LEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIR 491
++ ++ +G+N+ RMN SHG + H + ++ K + I DTKGPEIR
Sbjct: 41 IKDLILSGVNIFRMNLSHGDQKIHLFRTQLIKKIADELKIK------VEILFDTKGPEIR 94
>UniRef50_Q7NJ33 Cluster: Pyruvate kinase; n=1; Gloeobacter
violaceus|Rep: Pyruvate kinase - Gloeobacter violaceus
Length = 501
Score = 35.5 bits (78), Expect = 1.4
Identities = 25/83 (30%), Positives = 39/83 (46%), Gaps = 1/83 (1%)
Frame = +3
Query: 258 RLSGIICTI-GPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 434
R + I+ T+ A + +L ++ GMN AR+N H S + N R AE+
Sbjct: 142 RATRIMVTLPSEAEGDYRLLCALIRAGMNCARINCVHDSETVWERMVGNIRRAEREVGR- 200
Query: 435 LGSPFSLAIALDTKGPEIRTGLL 503
+ I +D GP++RTG L
Sbjct: 201 -----ACRILMDLGGPKLRTGPL 218
>UniRef50_Q9M3B6 Cluster: Pyruvate kinase; n=1; Arabidopsis
thaliana|Rep: Pyruvate kinase - Arabidopsis thaliana
(Mouse-ear cress)
Length = 710
Score = 35.5 bits (78), Expect = 1.4
Identities = 25/84 (29%), Positives = 42/84 (50%), Gaps = 1/84 (1%)
Frame = +3
Query: 258 RLSGIICTIGP-ASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 434
R + I+ TIG A+ + + +++ G +V R+N +HG E I+ R S
Sbjct: 234 RSTHIMVTIGEEATLSETFITDILKAGTSVIRINCAHGDPSIWGEIIKRVRRT----SQM 289
Query: 435 LGSPFSLAIALDTKGPEIRTGLLE 506
L P + +D GP++RTG L+
Sbjct: 290 LEMP--CRVHMDLAGPKLRTGTLK 311
>UniRef50_Q21J20 Cluster: Cell surface receptor IPT/TIG; n=1;
Saccharophagus degradans 2-40|Rep: Cell surface receptor
IPT/TIG - Saccharophagus degradans (strain 2-40 / ATCC
43961 / DSM 17024)
Length = 14609
Score = 35.1 bits (77), Expect = 1.9
Identities = 14/30 (46%), Positives = 21/30 (70%)
Frame = -3
Query: 308 SYITGCRSNSTDYSGETDYEDLESMSRPHI 219
SYI+ RS+ TD+ G TDYE+ S + P++
Sbjct: 11434 SYISNPRSSDTDWDGLTDYEEFNSGTNPNV 11463
>UniRef50_Q22CT0 Cluster: Pyruvate kinase, barrel domain containing
protein; n=1; Tetrahymena thermophila SB210|Rep:
Pyruvate kinase, barrel domain containing protein -
Tetrahymena thermophila SB210
Length = 747
Score = 33.9 bits (74), Expect = 4.4
Identities = 20/57 (35%), Positives = 33/57 (57%)
Frame = +2
Query: 521 EVELKKGETIKLTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSV 691
E+ L+KG+ ++ + ++ GN+ VD K I VK GN+I ID G IS+ + +
Sbjct: 145 EIFLRKGQEYRIVLN-HKVLGNSLYCAVDDKEIIRRVKVGNQILIDYGQISMTIKRI 200
>UniRef50_Q5V7K4 Cluster: Putative uncharacterized protein; n=1;
Haloarcula marismortui|Rep: Putative uncharacterized
protein - Haloarcula marismortui (Halobacterium
marismortui)
Length = 524
Score = 33.5 bits (73), Expect = 5.8
Identities = 12/31 (38%), Positives = 22/31 (70%)
Frame = +2
Query: 548 IKLTSSDYQEKGNADTIYVDYKNITNVVKPG 640
IK+T++D Q ++T+ + Y+N+TN +PG
Sbjct: 289 IKITTTDQQTVSGSETVLLRYENVTNPSRPG 319
>UniRef50_Q9V2V8 Cluster: Pyruvate kinase; n=1; Thermoproteus
tenax|Rep: Pyruvate kinase - Thermoproteus tenax
Length = 446
Score = 33.5 bits (73), Expect = 5.8
Identities = 22/78 (28%), Positives = 39/78 (50%)
Frame = +3
Query: 270 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 449
I+ T+GP++ + + ++ V R+N SH S + R+ E++ S
Sbjct: 5 IVATLGPSTDRLPDITALLSKVHGV-RINMSHASPSEVEARVNAVRKYEET------SGR 57
Query: 450 SLAIALDTKGPEIRTGLL 503
+AI D +GP +RTGL+
Sbjct: 58 YIAIIADLRGPSVRTGLM 75
>UniRef50_Q4T5N2 Cluster: Chromosome undetermined SCAF9187, whole
genome shotgun sequence; n=2; Tetraodontidae|Rep:
Chromosome undetermined SCAF9187, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 240
Score = 33.1 bits (72), Expect = 7.7
Identities = 11/33 (33%), Positives = 20/33 (60%)
Frame = -3
Query: 293 CRSNSTDYSGETDYEDLESMSRPHICWSWEPTL 195
CR + SG ++D++++ R H+CW + P L
Sbjct: 72 CRVENGGQSGNDSWKDVKNLCRLHLCWCFRPHL 104
>UniRef50_Q1D9T1 Cluster: 6-phosphofructokinase; n=1; Myxococcus
xanthus DK 1622|Rep: 6-phosphofructokinase - Myxococcus
xanthus (strain DK 1622)
Length = 315
Score = 33.1 bits (72), Expect = 7.7
Identities = 16/38 (42%), Positives = 22/38 (57%)
Frame = +3
Query: 429 AKLGSPFSLAIALDTKGPEIRTGLLEGAAQLKSN*RRE 542
A+LG ++ + +DT GP +R L EG K N RRE
Sbjct: 154 ARLGKRLAVRVVVDTNGPPLRAALEEGVFMAKPN-RRE 190
>UniRef50_Q3EBL2 Cluster: Uncharacterized protein At2g37440.1; n=3;
Arabidopsis thaliana|Rep: Uncharacterized protein
At2g37440.1 - Arabidopsis thaliana (Mouse-ear cress)
Length = 479
Score = 33.1 bits (72), Expect = 7.7
Identities = 18/40 (45%), Positives = 22/40 (55%)
Frame = -1
Query: 730 TSVFNGTRKSVSADRLTDDRDEAIIDEDSVSWLHDIRYVL 611
T +F TR S S+ D R E I+D D V WL D+ Y L
Sbjct: 276 TEIFKRTRFSRSSK---DSRPETIMDHDKVIWLGDLNYRL 312
>UniRef50_A1Y027 Cluster: Putative uncharacterized protein; n=1;
Spironucleus barkhanus|Rep: Putative uncharacterized
protein - Spironucleus barkhanus
Length = 858
Score = 33.1 bits (72), Expect = 7.7
Identities = 16/45 (35%), Positives = 21/45 (46%)
Frame = +2
Query: 629 VKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSGKASTCP 763
+KPG + DG+ + C S S T I +G L GK CP
Sbjct: 588 IKPGQGCYCTDGVATADCLSCSGATCATCI-SGSFLAGGKCERCP 631
>UniRef50_A2R204 Cluster: Contig An13c0090, complete genome; n=1;
Aspergillus niger|Rep: Contig An13c0090, complete genome
- Aspergillus niger
Length = 77
Score = 33.1 bits (72), Expect = 7.7
Identities = 14/26 (53%), Positives = 19/26 (73%)
Frame = -3
Query: 521 QLSRPFQESSSDLRSFSVQCDGQREG 444
Q+SRP SSS++RSFS+ +REG
Sbjct: 6 QISRPLVRSSSNMRSFSIAVPARREG 31
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 747,590,171
Number of Sequences: 1657284
Number of extensions: 14933457
Number of successful extensions: 42775
Number of sequences better than 10.0: 153
Number of HSP's better than 10.0 without gapping: 41080
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 42678
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 63381147830
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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