Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= br--1262
(819 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI00015B404E Cluster: PREDICTED: similar to ENSANGP000... 151 2e-35
UniRef50_O60256 Cluster: Phosphoribosyl pyrophosphate synthetase... 135 1e-30
UniRef50_A2AAG9 Cluster: Likely ortholog of H. sapiens phosphori... 124 2e-27
UniRef50_Q9VT33 Cluster: Ribose-phosphate pyrophosphokinase; n=4... 87 5e-16
UniRef50_A7M6E2 Cluster: Ribose-phosphate pyrophosphokinase I; n... 84 5e-15
UniRef50_A7TNR7 Cluster: Putative uncharacterized protein; n=1; ... 84 5e-15
UniRef50_Q0U4M1 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 83 6e-15
UniRef50_Q5KCA3 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 81 2e-14
UniRef50_Q5A4X7 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 81 2e-14
UniRef50_P60891 Cluster: Ribose-phosphate pyrophosphokinase 1; n... 81 4e-14
UniRef50_UPI000156094F Cluster: PREDICTED: similar to PRPS2 prot... 80 6e-14
UniRef50_Q16GA3 Cluster: Ribose-phosphate pyrophosphokinase 1, p... 80 6e-14
UniRef50_A7EV32 Cluster: Putative uncharacterized protein; n=1; ... 79 1e-13
UniRef50_A3LVW1 Cluster: Ribose-phosphate pyrophosphokinase; n=3... 79 1e-13
UniRef50_P32895 Cluster: Ribose-phosphate pyrophosphokinase 1; n... 79 1e-13
UniRef50_A1CDQ3 Cluster: Ribose-phosphate pyrophosphokinase; n=5... 77 7e-13
UniRef50_Q1DW45 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 76 1e-12
UniRef50_Q4P1D3 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 75 2e-12
UniRef50_A6R925 Cluster: Ribose-phosphate pyrophosphokinase I; n... 74 5e-12
UniRef50_Q6CG51 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 73 7e-12
UniRef50_Q4P9A7 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 73 9e-12
UniRef50_Q8X022 Cluster: Ribose-phosphate pyrophosphokinase; n=2... 72 2e-11
UniRef50_A5DKD0 Cluster: Ribose-phosphate pyrophosphokinase; n=2... 71 3e-11
UniRef50_Q12265 Cluster: Probable ribose-phosphate pyrophosphoki... 69 1e-10
UniRef50_Q7MT83 Cluster: Ribose-phosphate pyrophosphokinase; n=2... 64 3e-09
UniRef50_A4VV92 Cluster: Ribose-phosphate pyrophosphokinase; n=3... 64 4e-09
UniRef50_UPI00006CD8E2 Cluster: ribose-phosphate pyrophosphokina... 64 5e-09
UniRef50_A0CY99 Cluster: Chromosome undetermined scaffold_31, wh... 63 9e-09
UniRef50_Q1AXL6 Cluster: Ribose-phosphate pyrophosphokinase; n=3... 62 1e-08
UniRef50_Q88Z84 Cluster: Ribose-phosphate pyrophosphokinase 1; n... 62 1e-08
UniRef50_A3ZLP4 Cluster: Ribose-phosphate pyrophosphokinase; n=3... 62 2e-08
UniRef50_P65239 Cluster: Ribose-phosphate pyrophosphokinase 1; n... 62 2e-08
UniRef50_A0VM43 Cluster: Ribose-phosphate pyrophosphokinase; n=2... 61 3e-08
UniRef50_Q9U465 Cluster: Phosphoribosylpyrophosphate synthetase;... 61 3e-08
UniRef50_Q8R753 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 61 3e-08
UniRef50_Q6MW31 Cluster: Related to ribose-phosphate pyrophospho... 61 4e-08
UniRef50_Q1GEV9 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 60 5e-08
UniRef50_A4T068 Cluster: Ribose-phosphate pyrophosphokinase; n=2... 60 5e-08
UniRef50_Q75JN8 Cluster: Similar to ribose-phosphate pyrophospho... 60 5e-08
UniRef50_A4EBQ1 Cluster: Putative uncharacterized protein; n=1; ... 60 7e-08
UniRef50_Q8D2K5 Cluster: PrsA protein; n=1; Wigglesworthia gloss... 60 9e-08
UniRef50_Q8Y9L8 Cluster: Ribose-phosphate pyrophosphokinase 2; n... 60 9e-08
UniRef50_Q83GR1 Cluster: Ribose-phosphate pyrophosphokinase; n=3... 59 1e-07
UniRef50_Q822W0 Cluster: Ribose-phosphate pyrophosphokinase; n=2... 59 1e-07
UniRef50_Q42581 Cluster: Ribose-phosphate pyrophosphokinase 1; n... 59 1e-07
UniRef50_Q74LT0 Cluster: Phosphoribosylpyrophosphate synthetase;... 59 2e-07
UniRef50_A5URX1 Cluster: Ribose-phosphate pyrophosphokinase; n=3... 59 2e-07
UniRef50_UPI0000EB04C8 Cluster: UPI0000EB04C8 related cluster; n... 58 2e-07
UniRef50_Q6F241 Cluster: Ribose-phosphate pyrophosphokinase; n=6... 58 2e-07
UniRef50_UPI00005A2C8C Cluster: PREDICTED: similar to Ribose-pho... 58 3e-07
UniRef50_Q6Z2L5-2 Cluster: Isoform 2 of Q6Z2L5 ; n=1; Oryza sati... 58 3e-07
UniRef50_Q6MAT0 Cluster: Probable phosphoribosyl pyrophosphate s... 58 3e-07
UniRef50_Q8G5P2 Cluster: Ribose-phosphate pyrophosphokinase; n=5... 57 5e-07
UniRef50_Q075L4 Cluster: Plastid ribose-phosphate diphosphokinas... 57 6e-07
UniRef50_Q8IE40 Cluster: Ribose-phosphate pyrophosphokinase, put... 57 6e-07
UniRef50_Q9RUD2 Cluster: Probable ribose-phosphate pyrophosphoki... 57 6e-07
UniRef50_Q89DJ1 Cluster: Ribose-phosphate pyrophosphokinase; n=3... 57 6e-07
UniRef50_Q03YB5 Cluster: Ribose-phosphate pyrophosphokinase; n=2... 56 8e-07
UniRef50_Q4XQD5 Cluster: Ribose-phosphate pyrophosphokinase, put... 56 8e-07
UniRef50_P75044 Cluster: Ribose-phosphate pyrophosphokinase; n=6... 56 8e-07
UniRef50_Q0G092 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 56 1e-06
UniRef50_A5V1W5 Cluster: Ribose-phosphate pyrophosphokinase; n=5... 56 1e-06
UniRef50_Q4Q0M2 Cluster: Phosphoribosylpyrophosphate synthetase,... 55 2e-06
UniRef50_Q3M5L4 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 54 4e-06
UniRef50_Q4Q3Z4 Cluster: Phosphoribosylpyrophosphate synthetase,... 52 1e-05
UniRef50_Q2GIZ1 Cluster: Ribose-phosphate pyrophosphokinase; n=6... 52 2e-05
UniRef50_A0E424 Cluster: Chromosome undetermined scaffold_77, wh... 52 2e-05
UniRef50_Q8EUI1 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 51 3e-05
UniRef50_Q4UNC9 Cluster: Ribose-phosphate pyrophosphokinase; n=9... 51 3e-05
UniRef50_Q9PQV0 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 51 4e-05
UniRef50_A7ARJ1 Cluster: Ribose-phosphate pyrophosphokinase, put... 50 5e-05
UniRef50_Q98R83 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 50 5e-05
UniRef50_Q4QI56 Cluster: Phosphoribosylpyrophosphate synthetase;... 48 2e-04
UniRef50_A7HHV4 Cluster: Ribose-phosphate pyrophosphokinase; n=3... 48 3e-04
UniRef50_UPI00015BACA3 Cluster: ribose-phosphate pyrophosphokina... 46 0.001
UniRef50_Q5GTH9 Cluster: Phosphoribosylpyrophosphate synthetase;... 46 0.001
UniRef50_A2X0F3 Cluster: Ribose-phosphate pyrophosphokinase; n=2... 44 0.005
UniRef50_Q4DSS9 Cluster: Ribose-phosphate pyrophosphokinase, put... 43 0.011
UniRef50_Q97Z86 Cluster: Ribose-phosphate pyrophosphokinase; n=5... 43 0.011
UniRef50_Q8KKS6 Cluster: Ribose-phosphate pyrophosphokinase prot... 41 0.033
UniRef50_Q660Y0 Cluster: Phosphoribosyl pyrophosphate synthetase... 41 0.043
UniRef50_O62580 Cluster: Phosphoribosyl pyrophosphate synthetase... 41 0.043
UniRef50_Q9EWS0 Cluster: Putative ribose-phosphate pyrophosphoki... 41 0.043
UniRef50_A2XQT7 Cluster: Putative uncharacterized protein; n=1; ... 40 0.075
UniRef50_Q4QIB8 Cluster: Ribose-phosphate pyrophosphokinase, put... 40 0.100
UniRef50_A4BQ39 Cluster: Ribose-phosphate pyrophosphokinase; n=9... 38 0.23
UniRef50_A1HDW3 Cluster: Ribose-phosphate diphosphokinase; n=3; ... 38 0.40
UniRef50_Q8ZU24 Cluster: Ribose-phosphate pyrophosphokinase; n=4... 38 0.40
UniRef50_O26877 Cluster: Ribose-phosphate pyrophosphokinase; n=3... 38 0.40
UniRef50_Q3YQZ8 Cluster: Ribose-phosphate pyrophospho kinase; n=... 36 1.2
UniRef50_O83317 Cluster: Phosphoribosyl pyrophosphate synthetase... 36 1.6
UniRef50_A4WYL1 Cluster: Putative uncharacterized protein; n=1; ... 35 2.1
UniRef50_Q8TUT6 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 35 2.1
UniRef50_Q9F9G7 Cluster: Cwp66; n=19; Clostridium difficile|Rep:... 34 3.8
UniRef50_UPI0000EBE223 Cluster: PREDICTED: similar to OTTHUMP000... 33 6.6
UniRef50_O59586 Cluster: Ribose-phosphate pyrophosphokinase; n=4... 33 6.6
UniRef50_Q5A0L1 Cluster: Putative uncharacterized protein; n=1; ... 33 8.7
>UniRef50_UPI00015B404E Cluster: PREDICTED: similar to
ENSANGP00000018618; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ENSANGP00000018618 - Nasonia
vitripennis
Length = 322
Score = 151 bits (366), Expect = 2e-35
Identities = 69/78 (88%), Positives = 74/78 (94%)
Frame = +2
Query: 509 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIPESI 688
KMRKRGCIVSKLLA+MMCKSGL+H+ITMDLHQKEIQGFFDCPVDNLRASPFLLQYI ESI
Sbjct: 104 KMRKRGCIVSKLLAKMMCKSGLTHLITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESI 163
Query: 689 PDYRNSVIVARNPALQRK 742
PD+RNSVIVARNP +K
Sbjct: 164 PDFRNSVIVARNPGSAKK 181
Score = 144 bits (349), Expect = 2e-33
Identities = 88/177 (49%), Positives = 109/177 (61%), Gaps = 3/177 (1%)
Frame = +3
Query: 288 VRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASS 467
V+ GGC+VY+KTNRET+VEI DS+RGK+IYIIQTGTKDVNNNIMELLIMAYACKTSSA S
Sbjct: 30 VKNGGCAVYYKTNRETMVEIGDSVRGKDIYIIQTGTKDVNNNIMELLIMAYACKTSSAKS 89
Query: 468 IVGVIPYLPYSKQ*KCGNEDV*FLNF*PK-*CVNQVFHTLSLWIYTK--RKYKDFLTALL 638
IVGV+PYLPYSKQ K K C + + H +++ ++ K + + D L
Sbjct: 90 IVGVVPYLPYSKQCKMRKRGCIVSKLLAKMMCKSGLTHLITMDLHQKEIQGFFDCPVDNL 149
Query: 639 II*EHHHSYFSIYQKVFQITVIRL*WPGIRLCKESYFICRAMRLAIAVIHGDRRKPK 809
Y F+ +VI PG SY +RL IAVIHG++ K K
Sbjct: 150 RASPFLLQYIQESIPDFRNSVIVARNPGSAKKATSY--AERLRLGIAVIHGEQPKEK 204
>UniRef50_O60256 Cluster: Phosphoribosyl pyrophosphate
synthetase-associated protein 2; n=62; Eumetazoa|Rep:
Phosphoribosyl pyrophosphate synthetase-associated
protein 2 - Homo sapiens (Human)
Length = 369
Score = 135 bits (327), Expect = 1e-30
Identities = 62/78 (79%), Positives = 71/78 (91%)
Frame = +2
Query: 509 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIPESI 688
KMRKRG IVSKLLA MMCK+GL+H+ITMDLHQKEIQGFF+ PVDNLRASPFLLQYI E I
Sbjct: 118 KMRKRGSIVSKLLASMMCKAGLTHLITMDLHQKEIQGFFNIPVDNLRASPFLLQYIQEEI 177
Query: 689 PDYRNSVIVARNPALQRK 742
PDYRN+VIVA++PA ++
Sbjct: 178 PDYRNAVIVAKSPASAKR 195
Score = 104 bits (249), Expect = 3e-21
Identities = 49/75 (65%), Positives = 58/75 (77%)
Frame = +3
Query: 288 VRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASS 467
V G VY + NRET V+I +S+RGK+++IIQT +KDVN IMELLIM YACKTS A S
Sbjct: 44 VEMGKVQVYQEPNRETRVQIQESVRGKDVFIIQTVSKDVNTTIMELLIMVYACKTSCAKS 103
Query: 468 IVGVIPYLPYSKQ*K 512
I+GVIPY PYSKQ K
Sbjct: 104 IIGVIPYFPYSKQCK 118
>UniRef50_A2AAG9 Cluster: Likely ortholog of H. sapiens
phosphoribosyl pyrophosphate synthetase- associated
protein 1; n=21; Coelomata|Rep: Likely ortholog of H.
sapiens phosphoribosyl pyrophosphate synthetase-
associated protein 1 - Mus musculus (Mouse)
Length = 175
Score = 124 bits (300), Expect = 2e-27
Identities = 58/73 (79%), Positives = 65/73 (89%)
Frame = +2
Query: 509 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIPESI 688
KMRKRG IV KLLA M+ K+GL+HIITMDLHQKEIQGFF PVDNLRASPFLLQYI E I
Sbjct: 99 KMRKRGSIVCKLLASMLAKAGLTHIITMDLHQKEIQGFFSFPVDNLRASPFLLQYIQEEI 158
Query: 689 PDYRNSVIVARNP 727
P+YRN+VIVA++P
Sbjct: 159 PNYRNAVIVAKSP 171
Score = 93.1 bits (221), Expect = 8e-18
Identities = 45/72 (62%), Positives = 56/72 (77%)
Frame = +3
Query: 297 GGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVG 476
G VY +TN ET VEI +S+RG++I+IIQT +DVN +MELLIMAYA KT+ A +I+G
Sbjct: 28 GKSVVYQETNGETRVEIKESVRGQDIFIIQTIPRDVNTAVMELLIMAYALKTACARNIIG 87
Query: 477 VIPYLPYSKQ*K 512
VIPY PYSKQ K
Sbjct: 88 VIPYFPYSKQSK 99
>UniRef50_Q9VT33 Cluster: Ribose-phosphate pyrophosphokinase; n=4;
Fungi/Metazoa group|Rep: Ribose-phosphate
pyrophosphokinase - Drosophila melanogaster (Fruit fly)
Length = 388
Score = 87.0 bits (206), Expect = 5e-16
Identities = 39/70 (55%), Positives = 53/70 (75%)
Frame = +2
Query: 509 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIPESI 688
K R R I +KL+A M+ +G HIITMDLH +IQGFFD PVDNL A P +L++I E+I
Sbjct: 170 KFRSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIKENI 229
Query: 689 PDYRNSVIVA 718
P+++NS+IV+
Sbjct: 230 PEWKNSIIVS 239
Score = 80.6 bits (190), Expect = 4e-14
Identities = 37/73 (50%), Positives = 55/73 (75%), Gaps = 4/73 (5%)
Frame = +3
Query: 321 TNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVGVIPYLPYS 500
+N ET VEI +S+RG+++YI+Q+G+ ++N+N+MELLIM ACK +SAS + VIP PY+
Sbjct: 83 SNLETCVEIGESVRGEDVYIVQSGSGEINDNLMELLIMINACKIASASRVTAVIPCFPYA 142
Query: 501 KQ*K----CGNED 527
+Q K G+ED
Sbjct: 143 RQDKKDKLAGSED 155
>UniRef50_A7M6E2 Cluster: Ribose-phosphate pyrophosphokinase I; n=1;
Dugesia ryukyuensis|Rep: Ribose-phosphate
pyrophosphokinase I - Dugesia ryukyuensis
Length = 316
Score = 83.8 bits (198), Expect = 5e-15
Identities = 37/70 (52%), Positives = 54/70 (77%)
Frame = +3
Query: 321 TNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVGVIPYLPYS 500
+N ET V+I +S+RGK+++I+Q+G DVNN++MELLIM ACK +S++ I V+PY+PYS
Sbjct: 36 SNNETSVQIKESVRGKDVFILQSGYIDVNNHLMELLIMINACKNASSARITAVLPYMPYS 95
Query: 501 KQ*KCGNEDV 530
+Q K N V
Sbjct: 96 RQSKKDNNRV 105
Score = 60.1 bits (139), Expect = 7e-08
Identities = 30/82 (36%), Positives = 48/82 (58%)
Frame = +2
Query: 509 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIPESI 688
K R I +KL+A ++ +G +HIITMDLH +IQGFF+ PVDNL + + +I ++I
Sbjct: 100 KDNNRVPITAKLVADLLHIAGANHIITMDLHASQIQGFFNVPVDNLLSESCHISWIKKNI 159
Query: 689 PDYRNSVIVARNPALQRKLLHM 754
+ I + N ++ +M
Sbjct: 160 SKWEEITIFSLNVTSAERVANM 181
>UniRef50_A7TNR7 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 433
Score = 83.8 bits (198), Expect = 5e-15
Identities = 35/74 (47%), Positives = 54/74 (72%), Gaps = 1/74 (1%)
Frame = +2
Query: 509 KMRK-RGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIPES 685
KM+K RG I +++LA ++ +G H+I+MDLH ++QGFF PVDNL P L ++I E+
Sbjct: 99 KMKKHRGAITARMLANLLIMAGADHVISMDLHSSQMQGFFSKPVDNLYGGPSLARWIKEN 158
Query: 686 IPDYRNSVIVARNP 727
+ DY N+V+V++NP
Sbjct: 159 VEDYENAVVVSKNP 172
Score = 67.3 bits (157), Expect = 4e-10
Identities = 34/80 (42%), Positives = 47/80 (58%)
Frame = +3
Query: 273 CQPPRVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKT 452
CQ V C + N ET V+I S+R +++Y+IQ+ + +N++IMELLIM A
Sbjct: 20 CQRLGVEPAPCVLKKFVNGETSVQIGVSVRDEDVYVIQSSSNTLNDHIMELLIMVSAFSG 79
Query: 453 SSASSIVGVIPYLPYSKQ*K 512
SA + VIP PYSKQ K
Sbjct: 80 GSAGKVTAVIPMFPYSKQSK 99
>UniRef50_Q0U4M1 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Phaeosphaeria nodorum|Rep: Ribose-phosphate
pyrophosphokinase - Phaeosphaeria nodorum (Septoria
nodorum)
Length = 464
Score = 83.4 bits (197), Expect = 6e-15
Identities = 32/73 (43%), Positives = 56/73 (76%)
Frame = +2
Query: 509 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIPESI 688
K + RG I ++++A ++ +G++H+IT+DLH ++QGFF CPVDNL A P L ++I ++
Sbjct: 33 KKQHRGAITARMVANLLHVAGVNHVITLDLHASQMQGFFKCPVDNLVAEPLLSRWIRVNV 92
Query: 689 PDYRNSVIVARNP 727
P++R +V+V++NP
Sbjct: 93 PNWREAVVVSKNP 105
Score = 44.8 bits (101), Expect = 0.003
Identities = 21/32 (65%), Positives = 23/32 (71%)
Frame = +3
Query: 417 MELLIMAYACKTSSASSIVGVIPYLPYSKQ*K 512
MELLIM ACK SA SI V+PY PYS+Q K
Sbjct: 1 MELLIMISACKGGSAKSITAVMPYFPYSRQSK 32
>UniRef50_Q5KCA3 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Filobasidiella neoformans|Rep: Ribose-phosphate
pyrophosphokinase - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 357
Score = 81.4 bits (192), Expect = 2e-14
Identities = 35/70 (50%), Positives = 50/70 (71%)
Frame = +2
Query: 509 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIPESI 688
K + R I SKL+A ++ +G H+ITMDLH +IQGFFD PVDNL + P ++QYI I
Sbjct: 105 KDKSRAPITSKLVANLLAVAGADHVITMDLHASQIQGFFDIPVDNLFSEPTMMQYIKSEI 164
Query: 689 PDYRNSVIVA 718
P +R+++IV+
Sbjct: 165 PGWRDAIIVS 174
Score = 66.1 bits (154), Expect = 1e-09
Identities = 34/71 (47%), Positives = 49/71 (69%), Gaps = 1/71 (1%)
Frame = +3
Query: 303 CSVYHKTNRETIVEIADSIRGKNIYIIQTGTK-DVNNNIMELLIMAYACKTSSASSIVGV 479
C V + ET V+I S+R ++++IIQ+ + DVN+++MELLIM ACKT+SA I V
Sbjct: 34 CHVSKFRSLETSVQIHSSVRDEDVFIIQSPSPPDVNDHLMELLIMISACKTASAKRITAV 93
Query: 480 IPYLPYSKQ*K 512
IP PY++Q K
Sbjct: 94 IPCYPYARQDK 104
>UniRef50_Q5A4X7 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Candida albicans|Rep: Ribose-phosphate pyrophosphokinase
- Candida albicans (Yeast)
Length = 404
Score = 81.4 bits (192), Expect = 2e-14
Identities = 34/74 (45%), Positives = 54/74 (72%), Gaps = 1/74 (1%)
Frame = +2
Query: 509 KMRK-RGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIPES 685
KM+K RG I +++LA ++ +G H+++MDLH ++QGFF PVDNL +P L ++I
Sbjct: 99 KMKKHRGAITARMLANLLVMAGADHVVSMDLHASQMQGFFSKPVDNLFGAPTLARWIRHH 158
Query: 686 IPDYRNSVIVARNP 727
IPD+ N+V+V++NP
Sbjct: 159 IPDWENAVVVSKNP 172
Score = 75.4 bits (177), Expect = 2e-12
Identities = 39/98 (39%), Positives = 59/98 (60%)
Frame = +3
Query: 219 RRTLLF*VETHI*IS*FDCQPPRVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTK 398
R+ +F +H + C V C++ +N ET V+I S+R +++YIIQ+G+
Sbjct: 2 RKCKIFVGSSHPELGQLVCDRLGVEPAPCTLKKFSNGETSVQIGVSVRDEDVYIIQSGSP 61
Query: 399 DVNNNIMELLIMAYACKTSSASSIVGVIPYLPYSKQ*K 512
+N++IMELLI+ AC+ SA+ I VIP PYSKQ K
Sbjct: 62 HINDHIMELLILISACRGGSANKITAVIPQFPYSKQSK 99
>UniRef50_P60891 Cluster: Ribose-phosphate pyrophosphokinase 1;
n=156; Eukaryota|Rep: Ribose-phosphate pyrophosphokinase
1 - Homo sapiens (Human)
Length = 318
Score = 80.6 bits (190), Expect = 4e-14
Identities = 34/64 (53%), Positives = 51/64 (79%)
Frame = +3
Query: 321 TNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVGVIPYLPYS 500
+N+ET VEI +S+RG+++YI+Q+G ++N+N+MELLIM ACK +SAS + VIP PY+
Sbjct: 36 SNQETCVEIGESVRGEDVYIVQSGCGEINDNLMELLIMINACKIASASRVTAVIPCFPYA 95
Query: 501 KQ*K 512
+Q K
Sbjct: 96 RQDK 99
Score = 79.0 bits (186), Expect = 1e-13
Identities = 37/70 (52%), Positives = 50/70 (71%)
Frame = +2
Query: 509 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIPESI 688
K + R I +KL+A M+ +G HIITMDLH +IQGFFD PVDNL A P +L++I E+I
Sbjct: 100 KDKSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIRENI 159
Query: 689 PDYRNSVIVA 718
++RN IV+
Sbjct: 160 SEWRNCTIVS 169
>UniRef50_UPI000156094F Cluster: PREDICTED: similar to PRPS2
protein; n=2; Mammalia|Rep: PREDICTED: similar to PRPS2
protein - Equus caballus
Length = 301
Score = 80.2 bits (189), Expect = 6e-14
Identities = 34/66 (51%), Positives = 51/66 (77%)
Frame = +3
Query: 315 HKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVGVIPYLP 494
H N +T+VEI +S+RG+++YIIQ+G ++N+N+MELLIM ACK +S+S + VIP P
Sbjct: 17 HTKNGKTLVEIGESVRGEDVYIIQSGCGEINDNLMELLIMINACKIASSSRVTAVIPCFP 76
Query: 495 YSKQ*K 512
Y++Q K
Sbjct: 77 YARQDK 82
Score = 79.8 bits (188), Expect = 8e-14
Identities = 37/70 (52%), Positives = 50/70 (71%)
Frame = +2
Query: 509 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIPESI 688
K + R I +KL+A M+ +G HIITMDLH +IQGFFD PVDNL A P +LQ+I E+I
Sbjct: 83 KDKSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLQWIRENI 142
Query: 689 PDYRNSVIVA 718
++N +IV+
Sbjct: 143 AQWKNCIIVS 152
>UniRef50_Q16GA3 Cluster: Ribose-phosphate pyrophosphokinase 1,
putative; n=2; Aedes aegypti|Rep: Ribose-phosphate
pyrophosphokinase 1, putative - Aedes aegypti
(Yellowfever mosquito)
Length = 330
Score = 80.2 bits (189), Expect = 6e-14
Identities = 34/64 (53%), Positives = 51/64 (79%)
Frame = +3
Query: 321 TNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVGVIPYLPYS 500
+N ET VEI +S+RG+++YI+Q+G+ ++N+N+MELLIM ACK +SAS + VIP PY+
Sbjct: 72 SNLETCVEIGESVRGEDVYIVQSGSGEINDNLMELLIMINACKIASASRVTAVIPCFPYA 131
Query: 501 KQ*K 512
+Q K
Sbjct: 132 RQDK 135
>UniRef50_A7EV32 Cluster: Putative uncharacterized protein; n=1;
Sclerotinia sclerotiorum 1980|Rep: Putative
uncharacterized protein - Sclerotinia sclerotiorum 1980
Length = 526
Score = 79.4 bits (187), Expect = 1e-13
Identities = 30/72 (41%), Positives = 52/72 (72%)
Frame = +2
Query: 509 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIPESI 688
K RG I +++LA ++ +G++H+IT+DLH ++QGFF CPVDNL A P + ++I ++
Sbjct: 100 KKSHRGAITARMLANLLHVAGINHVITVDLHASQMQGFFKCPVDNLHAEPLIARWIRRNV 159
Query: 689 PDYRNSVIVARN 724
P++ +V V++N
Sbjct: 160 PEWNEAVCVSKN 171
Score = 74.1 bits (174), Expect = 4e-12
Identities = 33/63 (52%), Positives = 47/63 (74%)
Frame = +3
Query: 324 NRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVGVIPYLPYSK 503
N ET V+I SIR K+++++Q+G+ +N++IMELLIM ACK SA+ I V+PY PYS+
Sbjct: 37 NGETSVKIMTSIREKDVFVVQSGSSKINDSIMELLIMISACKGGSANKITAVLPYFPYSR 96
Query: 504 Q*K 512
Q K
Sbjct: 97 QSK 99
>UniRef50_A3LVW1 Cluster: Ribose-phosphate pyrophosphokinase; n=3;
Saccharomycetales|Rep: Ribose-phosphate
pyrophosphokinase - Pichia stipitis (Yeast)
Length = 451
Score = 79.4 bits (187), Expect = 1e-13
Identities = 36/78 (46%), Positives = 53/78 (67%)
Frame = +3
Query: 273 CQPPRVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKT 452
C+ + +G S +N ET +EI DS+R K+++I+Q+G DVN+N +ELLIM ACKT
Sbjct: 20 CRNLTIEQGEVSSRKFSNGETSLEIQDSVREKDVFIVQSGCGDVNDNFIELLIMIAACKT 79
Query: 453 SSASSIVGVIPYLPYSKQ 506
+SA + V+P PYS+Q
Sbjct: 80 ASAKRVTAVLPLFPYSRQ 97
Score = 64.5 bits (150), Expect = 3e-09
Identities = 28/59 (47%), Positives = 40/59 (67%)
Frame = +2
Query: 542 LLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIPESIPDYRNSVIVA 718
L+A ++ +G +ITMDLH + QGFF+ PVDNL + P L YI + IP+Y+ VIV+
Sbjct: 215 LIANLLVTAGADRLITMDLHDPQFQGFFNIPVDNLYSRPLLKHYILDYIPNYQECVIVS 273
>UniRef50_P32895 Cluster: Ribose-phosphate pyrophosphokinase 1;
n=11; Ascomycota|Rep: Ribose-phosphate pyrophosphokinase
1 - Saccharomyces cerevisiae (Baker's yeast)
Length = 427
Score = 79.4 bits (187), Expect = 1e-13
Identities = 31/71 (43%), Positives = 51/71 (71%)
Frame = +2
Query: 515 RKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIPESIPD 694
R RG I +++LA ++ +G H+++MDLH ++QGFF PVDNL P L ++I E++ D
Sbjct: 102 RHRGAITARMLANLLVMAGADHVVSMDLHASQMQGFFTKPVDNLYGGPSLAKWIRENVED 161
Query: 695 YRNSVIVARNP 727
Y ++V+V++NP
Sbjct: 162 YEDAVVVSKNP 172
Score = 76.2 bits (179), Expect = 9e-13
Identities = 38/98 (38%), Positives = 58/98 (59%)
Frame = +3
Query: 219 RRTLLF*VETHI*IS*FDCQPPRVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTK 398
R+ +F +H + CQ + C++ N ET V+I S+R +++Y+IQ+G+
Sbjct: 2 RKCKIFVGNSHPELGNMVCQRLGIEPAPCTLKKFANGETSVQIGVSVRDEDVYVIQSGSP 61
Query: 399 DVNNNIMELLIMAYACKTSSASSIVGVIPYLPYSKQ*K 512
+N++IMELLI+ AC+ SA I VIP PYSKQ K
Sbjct: 62 SINDDIMELLILVSACRGGSARKITAVIPQFPYSKQCK 99
>UniRef50_A1CDQ3 Cluster: Ribose-phosphate pyrophosphokinase; n=5;
Pezizomycotina|Rep: Ribose-phosphate pyrophosphokinase -
Aspergillus clavatus
Length = 489
Score = 76.6 bits (180), Expect = 7e-13
Identities = 30/72 (41%), Positives = 52/72 (72%)
Frame = +2
Query: 509 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIPESI 688
K RG I +++LA ++ +G+ H+IT+DLH ++QGFF PVDNL A PF+ ++I ++
Sbjct: 101 KKSHRGAITARMLANLLSVAGVDHVITLDLHASQMQGFFGKPVDNLFAEPFIARWIRMNV 160
Query: 689 PDYRNSVIVARN 724
P ++ +V+V++N
Sbjct: 161 PGWKEAVVVSKN 172
Score = 66.1 bits (154), Expect = 1e-09
Identities = 32/64 (50%), Positives = 46/64 (71%), Gaps = 1/64 (1%)
Frame = +3
Query: 324 NRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVGV-IPYLPYS 500
N ET V+I S+R +++YI+Q+G++ +N+++MELLIM ACK SA SI G Y PYS
Sbjct: 37 NGETRVDIGVSVRNQDVYILQSGSQKINDSVMELLIMISACKGGSAKSITGQWTRYFPYS 96
Query: 501 KQ*K 512
+Q K
Sbjct: 97 RQSK 100
>UniRef50_Q1DW45 Cluster: Ribose-phosphate pyrophosphokinase; n=11;
Ascomycota|Rep: Ribose-phosphate pyrophosphokinase -
Coccidioides immitis
Length = 509
Score = 75.8 bits (178), Expect = 1e-12
Identities = 33/70 (47%), Positives = 49/70 (70%)
Frame = +3
Query: 303 CSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVGVI 482
C + +N ET V I S+R ++++I+Q+G+ +N+++MELLIM ACK SA SI V+
Sbjct: 30 CELRKFSNGETCVNIGVSVRNQDVFIVQSGSSKINDSVMELLIMISACKGGSAKSITAVL 89
Query: 483 PYLPYSKQ*K 512
PY PYS+Q K
Sbjct: 90 PYFPYSRQSK 99
Score = 68.1 bits (159), Expect = 2e-10
Identities = 28/72 (38%), Positives = 48/72 (66%)
Frame = +2
Query: 509 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIPESI 688
K RG I +++LA ++ +G+ H+IT+DLH ++QGFF PVDNL A + ++I ++
Sbjct: 100 KKSHRGAITARMLANLLSIAGVDHVITVDLHASQMQGFFGKPVDNLFAESLIARWIRINV 159
Query: 689 PDYRNSVIVARN 724
P + +V+V +N
Sbjct: 160 PRWHEAVVVTKN 171
>UniRef50_Q4P1D3 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Ustilago maydis|Rep: Ribose-phosphate pyrophosphokinase
- Ustilago maydis (Smut fungus)
Length = 432
Score = 75.4 bits (177), Expect = 2e-12
Identities = 37/70 (52%), Positives = 47/70 (67%)
Frame = +2
Query: 509 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIPESI 688
K + R I +KL+A M+ +G H+ITMDLH +IQGFFD PVDNL A P LQYI E +
Sbjct: 113 KDKSRAPITAKLIANMLENAGCDHVITMDLHASQIQGFFDVPVDNLYAEPAALQYIREMV 172
Query: 689 PDYRNSVIVA 718
D +VIV+
Sbjct: 173 -DVNKAVIVS 181
Score = 57.6 bits (133), Expect = 4e-07
Identities = 33/81 (40%), Positives = 47/81 (58%), Gaps = 9/81 (11%)
Frame = +3
Query: 297 GGCSVYHKTNRETIVEIADSIRGKNIYIIQTG---------TKDVNNNIMELLIMAYACK 449
G +V + E+IV IA+S+R ++YII T N ++MELLIM +ACK
Sbjct: 32 GKATVTRNESGESIVRIAESVREHDVYIINTSCVSPTPTGAAASPNTSLMELLIMIHACK 91
Query: 450 TSSASSIVGVIPYLPYSKQ*K 512
T+SA I VIP+ Y++Q K
Sbjct: 92 TASAKRITAVIPHFFYARQDK 112
>UniRef50_A6R925 Cluster: Ribose-phosphate pyrophosphokinase I;
n=20; Pezizomycotina|Rep: Ribose-phosphate
pyrophosphokinase I - Ajellomyces capsulatus NAm1
Length = 456
Score = 73.7 bits (173), Expect = 5e-12
Identities = 32/59 (54%), Positives = 46/59 (77%)
Frame = +3
Query: 330 ETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVGVIPYLPYSKQ 506
ET VEI +S+RGK++YIIQ+G VN+++MELL++ ACKT+SA + V+P PYS+Q
Sbjct: 40 ETRVEINESVRGKDVYIIQSGGGKVNDHLMELLVIISACKTASAKRVTAVLPLFPYSRQ 98
Score = 73.3 bits (172), Expect = 7e-12
Identities = 32/59 (54%), Positives = 43/59 (72%)
Frame = +2
Query: 542 LLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIPESIPDYRNSVIVA 718
L+A ++ +G HIITMDLH + QGFFD PVDNL P L +YI E+IP+Y+ S+IV+
Sbjct: 247 LVADLLTCAGADHIITMDLHDPQYQGFFDIPVDNLYGRPLLKKYITENIPNYKASIIVS 305
>UniRef50_Q6CG51 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Yarrowia lipolytica|Rep: Ribose-phosphate
pyrophosphokinase - Yarrowia lipolytica (Candida
lipolytica)
Length = 370
Score = 73.3 bits (172), Expect = 7e-12
Identities = 32/61 (52%), Positives = 44/61 (72%)
Frame = +3
Query: 324 NRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVGVIPYLPYSK 503
N ET V I DS+R K++Y++Q+G VN+N +ELLIM ACKT+SA + V+P PYS+
Sbjct: 37 NGETSVTIRDSVREKDVYVVQSGCGHVNDNFIELLIMISACKTASAKKVTAVMPLFPYSR 96
Query: 504 Q 506
Q
Sbjct: 97 Q 97
Score = 71.3 bits (167), Expect = 3e-11
Identities = 31/59 (52%), Positives = 41/59 (69%)
Frame = +2
Query: 542 LLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIPESIPDYRNSVIVA 718
L+A ++ +G HIITMDLH + QGFFD PVDNL P L YI IP+Y+++VIV+
Sbjct: 154 LIASLLTCAGADHIITMDLHDPQFQGFFDIPVDNLYGKPLLQHYISTQIPNYQDAVIVS 212
>UniRef50_Q4P9A7 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Ustilago maydis|Rep: Ribose-phosphate pyrophosphokinase
- Ustilago maydis (Smut fungus)
Length = 458
Score = 72.9 bits (171), Expect = 9e-12
Identities = 31/70 (44%), Positives = 48/70 (68%)
Frame = +2
Query: 509 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIPESI 688
K + R I +KL+A M+ +G H+ITMDLH +IQGFFD PVDNL + P + ++I +
Sbjct: 106 KDKSRAPITAKLVANMLTVAGADHVITMDLHASQIQGFFDIPVDNLTSEPSVARWIRSKV 165
Query: 689 PDYRNSVIVA 718
++R ++IV+
Sbjct: 166 ENWREAIIVS 175
Score = 60.5 bits (140), Expect = 5e-08
Identities = 29/61 (47%), Positives = 41/61 (67%), Gaps = 3/61 (4%)
Frame = +3
Query: 339 VEIADSIRGKNIYIIQTGTK---DVNNNIMELLIMAYACKTSSASSIVGVIPYLPYSKQ* 509
V I S+R +++Y++QTG D N+++MELLI+ ACKT+SA I VIP PYS+
Sbjct: 45 VRIGSSVRDEDVYVLQTGNSPYTDPNDSLMELLILLSACKTASARRITAVIPSFPYSRHD 104
Query: 510 K 512
K
Sbjct: 105 K 105
>UniRef50_Q8X022 Cluster: Ribose-phosphate pyrophosphokinase; n=2;
Pezizomycotina|Rep: Ribose-phosphate pyrophosphokinase -
Neurospora crassa
Length = 431
Score = 72.1 bits (169), Expect = 2e-11
Identities = 29/59 (49%), Positives = 44/59 (74%)
Frame = +2
Query: 542 LLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIPESIPDYRNSVIVA 718
L+A ++ +G H+ITMDLH ++QGFFD PVDNL P L +YI + IP++R++VI++
Sbjct: 202 LVANLLTCAGCDHVITMDLHDPQVQGFFDIPVDNLYGQPLLKRYIQQHIPNWRDAVIIS 260
Score = 63.3 bits (147), Expect = 7e-09
Identities = 31/63 (49%), Positives = 42/63 (66%), Gaps = 4/63 (6%)
Frame = +3
Query: 330 ETIVEIADSIRGKNIYIIQTGT----KDVNNNIMELLIMAYACKTSSASSIVGVIPYLPY 497
E+ EI DS+RGK++YIIQTG +N++ M+L IM ACKT SA + V+P PY
Sbjct: 40 ESRCEIQDSVRGKDVYIIQTGFGGNGSRLNDHFMDLCIMISACKTGSARRVTAVLPLFPY 99
Query: 498 SKQ 506
S+Q
Sbjct: 100 SRQ 102
>UniRef50_A5DKD0 Cluster: Ribose-phosphate pyrophosphokinase; n=2;
Saccharomycetaceae|Rep: Ribose-phosphate
pyrophosphokinase - Pichia guilliermondii (Yeast)
(Candida guilliermondii)
Length = 472
Score = 71.3 bits (167), Expect = 3e-11
Identities = 30/62 (48%), Positives = 46/62 (74%)
Frame = +3
Query: 321 TNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVGVIPYLPYS 500
+N ET +EI S+R K+++IIQ+G+ +N+N ++LLIM ACKT+SA + V+P PYS
Sbjct: 36 SNGETSIEIQGSVRDKDVFIIQSGSGHINDNFVQLLIMIAACKTASARRVTAVLPLFPYS 95
Query: 501 KQ 506
+Q
Sbjct: 96 RQ 97
Score = 63.3 bits (147), Expect = 7e-09
Identities = 27/59 (45%), Positives = 39/59 (66%)
Frame = +2
Query: 542 LLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIPESIPDYRNSVIVA 718
L+A ++ +G +TMDLH + QGFF+ PVDNL + P L YI + IP+Y+ VIV+
Sbjct: 232 LIANLLMTAGADRCVTMDLHDPQFQGFFNIPVDNLYSKPLLKHYIIDYIPNYQQCVIVS 290
>UniRef50_Q12265 Cluster: Probable ribose-phosphate
pyrophosphokinase 5; n=6; Saccharomycetales|Rep:
Probable ribose-phosphate pyrophosphokinase 5 -
Saccharomyces cerevisiae (Baker's yeast)
Length = 496
Score = 69.3 bits (162), Expect = 1e-10
Identities = 35/79 (44%), Positives = 51/79 (64%)
Frame = +3
Query: 270 DCQPPRVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACK 449
D P +V G S N ET + + +S+R K++YIIQ+G VN+ M+LLI+ ACK
Sbjct: 26 DIHPSKVELGKFS-----NGETNIALRESVREKDVYIIQSGCGQVNDTFMQLLILISACK 80
Query: 450 TSSASSIVGVIPYLPYSKQ 506
++SAS + V+PYL YS+Q
Sbjct: 81 SASASRVTAVMPYLCYSRQ 99
Score = 69.3 bits (162), Expect = 1e-10
Identities = 29/59 (49%), Positives = 39/59 (66%)
Frame = +2
Query: 542 LLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIPESIPDYRNSVIVA 718
L+A ++ +G H+ITMDLH + GFFD PVDNL P YI IPDY+++VIV+
Sbjct: 225 LIAHLLSAAGADHVITMDLHDPQFPGFFDIPVDNLYCKPIAQNYIQHRIPDYQDAVIVS 283
>UniRef50_Q7MT83 Cluster: Ribose-phosphate pyrophosphokinase; n=25;
Bacteria|Rep: Ribose-phosphate pyrophosphokinase -
Porphyromonas gingivalis (Bacteroides gingivalis)
Length = 313
Score = 64.5 bits (150), Expect = 3e-09
Identities = 28/61 (45%), Positives = 44/61 (72%)
Frame = +2
Query: 509 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIPESI 688
K + R I +KL+A ++ K+G++ +ITMDLH +IQGFFD PVD+L S ++YI +++
Sbjct: 102 KDKPRVSIGAKLIADLLSKAGITRLITMDLHADQIQGFFDVPVDHLYGSTVFMEYIRKNM 161
Query: 689 P 691
P
Sbjct: 162 P 162
Score = 52.8 bits (121), Expect = 1e-05
Identities = 26/70 (37%), Positives = 45/70 (64%)
Frame = +3
Query: 297 GGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVG 476
G ++ H + E V +SIRG++++++Q+ T ++N+MELL+M A K +SA I
Sbjct: 31 GRMNIEHFADGEFAVSYEESIRGRDVFLVQS-TFPSSDNLMELLLMIDAAKRASAHYITA 89
Query: 477 VIPYLPYSKQ 506
VIPY +++Q
Sbjct: 90 VIPYFGWARQ 99
>UniRef50_A4VV92 Cluster: Ribose-phosphate pyrophosphokinase; n=3;
Streptococcus suis|Rep: Ribose-phosphate
pyrophosphokinase - Streptococcus suis (strain 05ZYH33)
Length = 333
Score = 64.1 bits (149), Expect = 4e-09
Identities = 29/59 (49%), Positives = 43/59 (72%)
Frame = +3
Query: 330 ETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVGVIPYLPYSKQ 506
E + I +S+RG ++YIIQ+ + VNN++ ELLIM ACK +SA++I VIPY Y++Q
Sbjct: 53 EIQINIEESVRGVDVYIIQSTSYPVNNHLWELLIMIDACKRASANTITAVIPYFGYARQ 111
Score = 61.7 bits (143), Expect = 2e-08
Identities = 30/71 (42%), Positives = 44/71 (61%), Gaps = 1/71 (1%)
Frame = +2
Query: 530 IVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIPESIPDYRNSV 709
I +KL+A M+ K+G+ ++T+DLH +IQGFFD PVDNL P Y E + V
Sbjct: 121 ITAKLVANMLVKAGVDRVLTLDLHASQIQGFFDIPVDNLLTEPLFAAYYMEKGLCGEDVV 180
Query: 710 IVA-RNPALQR 739
IV+ +N ++R
Sbjct: 181 IVSPKNSGIKR 191
>UniRef50_UPI00006CD8E2 Cluster: ribose-phosphate pyrophosphokinase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
ribose-phosphate pyrophosphokinase family protein -
Tetrahymena thermophila SB210
Length = 447
Score = 63.7 bits (148), Expect = 5e-09
Identities = 28/68 (41%), Positives = 45/68 (66%), Gaps = 1/68 (1%)
Frame = +3
Query: 306 SVYHKTNRETIVEIADSIRGKNIYIIQTGTK-DVNNNIMELLIMAYACKTSSASSIVGVI 482
S++ ET +EI DS+RGK +++IQ+ + +N+NIMEL +M A K S A+ + ++
Sbjct: 126 SIHKNPESETEIEILDSVRGKRVFVIQSLCQPSINDNIMELYLMCSALKRSGAAKVTCIV 185
Query: 483 PYLPYSKQ 506
PY YS+Q
Sbjct: 186 PYFAYSRQ 193
>UniRef50_A0CY99 Cluster: Chromosome undetermined scaffold_31, whole
genome shotgun sequence; n=2; Oligohymenophorea|Rep:
Chromosome undetermined scaffold_31, whole genome
shotgun sequence - Paramecium tetraurelia
Length = 394
Score = 62.9 bits (146), Expect = 9e-09
Identities = 26/73 (35%), Positives = 50/73 (68%)
Frame = +3
Query: 288 VRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASS 467
++ G ++ + E +++ D+IRGK+++IIQ+ + VN+N+MELL++ A + +SA
Sbjct: 91 IKLGSVTIGRFADGECQIQVLDNIRGKDVFIIQSTSPPVNDNLMELLLLVSALRRASARK 150
Query: 468 IVGVIPYLPYSKQ 506
I+ V+PY Y++Q
Sbjct: 151 IIVVVPYYGYARQ 163
Score = 35.9 bits (79), Expect = 1.2
Identities = 18/46 (39%), Positives = 29/46 (63%), Gaps = 2/46 (4%)
Frame = +2
Query: 545 LAQMMCKSGLSHIITMDLHQKEIQGFFD--CPVDNLRASPFLLQYI 676
+A+++ G+ +I++DLH +IQGFF PVDNL A+ Y+
Sbjct: 178 VARLLETVGVDRLISVDLHCGQIQGFFGPRVPVDNLEANLVAQNYL 223
>UniRef50_Q1AXL6 Cluster: Ribose-phosphate pyrophosphokinase; n=3;
Bacteria|Rep: Ribose-phosphate pyrophosphokinase -
Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 331
Score = 62.5 bits (145), Expect = 1e-08
Identities = 29/70 (41%), Positives = 43/70 (61%)
Frame = +3
Query: 297 GGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVG 476
G + +N E +S+RG +++I+Q+ VN N+MELL+M A K +SA SIV
Sbjct: 39 GSVELVQFSNGEVYARYLESVRGSDVFIVQSLCDPVNKNLMELLVMVDAAKRASAESIVA 98
Query: 477 VIPYLPYSKQ 506
VIP+ YS+Q
Sbjct: 99 VIPWYAYSRQ 108
Score = 53.2 bits (122), Expect = 8e-06
Identities = 27/71 (38%), Positives = 45/71 (63%), Gaps = 1/71 (1%)
Frame = +2
Query: 509 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRA-SPFLLQYIPES 685
K + R I ++L+A+M+ +G I+TMDLH +I+GFF PVD+L A F+ ++ E
Sbjct: 111 KTKPREPITARLVAEMLKVAGADRIMTMDLHVGQIEGFFSFPVDHLTAMHTFVDHFVDEG 170
Query: 686 IPDYRNSVIVA 718
+ ++V+VA
Sbjct: 171 FQNAPDTVVVA 181
>UniRef50_Q88Z84 Cluster: Ribose-phosphate pyrophosphokinase 1;
n=77; Bacteria|Rep: Ribose-phosphate pyrophosphokinase 1
- Lactobacillus plantarum
Length = 326
Score = 62.5 bits (145), Expect = 1e-08
Identities = 33/73 (45%), Positives = 48/73 (65%)
Frame = +3
Query: 288 VRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASS 467
V+ G SV ++ E + I +SIRG +YIIQ+ + VN+N+MELLIM A + +SA +
Sbjct: 31 VKLGKTSVDRFSDGEIRINIEESIRGDQVYIIQSTSAPVNDNLMELLIMIDALRRASAKT 90
Query: 468 IVGVIPYLPYSKQ 506
I VIPY Y++Q
Sbjct: 91 INVVIPYYGYARQ 103
Score = 58.4 bits (135), Expect = 2e-07
Identities = 29/70 (41%), Positives = 43/70 (61%)
Frame = +2
Query: 509 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIPESI 688
K R R I +KL+A M+ +G + I+ +DLH +IQGFFD P+D+L +P L Y
Sbjct: 106 KARSREPITAKLVANMLETAGATRILALDLHAAQIQGFFDIPLDHLMGAPLLADYFLNHH 165
Query: 689 PDYRNSVIVA 718
D N+V+V+
Sbjct: 166 LD-ENAVVVS 174
>UniRef50_A3ZLP4 Cluster: Ribose-phosphate pyrophosphokinase; n=3;
Bacteria|Rep: Ribose-phosphate pyrophosphokinase -
Blastopirellula marina DSM 3645
Length = 328
Score = 62.1 bits (144), Expect = 2e-08
Identities = 27/59 (45%), Positives = 40/59 (67%)
Frame = +3
Query: 330 ETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVGVIPYLPYSKQ 506
E +I + +RG+++++IQ VNNNIMELLIM +C+ +SA I VIPY Y++Q
Sbjct: 45 ENACKIEEDVRGRDVFLIQPTCPPVNNNIMELLIMIDSCRRASAERITAVIPYFGYARQ 103
Score = 53.2 bits (122), Expect = 8e-06
Identities = 25/75 (33%), Positives = 46/75 (61%), Gaps = 1/75 (1%)
Frame = +2
Query: 530 IVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIPE-SIPDYRNS 706
I +KL++ ++ +G ++TMDLH +IQGFF+ PVD+L A+P L + +IP+
Sbjct: 113 ITAKLVSDVITAAGADRVLTMDLHAAQIQGFFNVPVDHLYAAPVLNHFFQALNIPEDELV 172
Query: 707 VIVARNPALQRKLLH 751
++ +++R + H
Sbjct: 173 IVSPDAGSIKRAVSH 187
>UniRef50_P65239 Cluster: Ribose-phosphate pyrophosphokinase 1;
n=143; Bacteria|Rep: Ribose-phosphate pyrophosphokinase
1 - Streptococcus pneumoniae
Length = 322
Score = 62.1 bits (144), Expect = 2e-08
Identities = 30/73 (41%), Positives = 49/73 (67%)
Frame = +3
Query: 288 VRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASS 467
+ G SV ++ E V I +SIRGK+++I+Q+ + VN+N++E+LIM A K +SA S
Sbjct: 27 IELGKSSVRQFSDGEIQVNIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAES 86
Query: 468 IVGVIPYLPYSKQ 506
+ V+PY Y++Q
Sbjct: 87 VNVVMPYYGYARQ 99
Score = 58.8 bits (136), Expect = 2e-07
Identities = 26/55 (47%), Positives = 37/55 (67%)
Frame = +2
Query: 509 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQY 673
K R R I SKL+A M+ +G+ ++T+DLH +IQGFFD PVD+L +P + Y
Sbjct: 102 KARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADY 156
>UniRef50_A0VM43 Cluster: Ribose-phosphate pyrophosphokinase; n=20;
Proteobacteria|Rep: Ribose-phosphate pyrophosphokinase -
Dinoroseobacter shibae DFL 12
Length = 340
Score = 61.3 bits (142), Expect = 3e-08
Identities = 26/59 (44%), Positives = 43/59 (72%)
Frame = +3
Query: 330 ETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVGVIPYLPYSKQ 506
E VE+ +++RG++++IIQ+ + N+N+MELLIM A + SSA+ I +IPY Y++Q
Sbjct: 48 EIFVEVFENVRGEDMFIIQSTSNPANDNLMELLIMCDALRRSSAARITAIIPYFGYARQ 106
Score = 61.3 bits (142), Expect = 3e-08
Identities = 26/50 (52%), Positives = 37/50 (74%)
Frame = +2
Query: 509 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASP 658
+ + R I +KL+A MM ++G+ ++TMDLH +IQGFFD PVDNL A+P
Sbjct: 109 RTKARTPITAKLVANMMVEAGIERVLTMDLHAAQIQGFFDIPVDNLYAAP 158
>UniRef50_Q9U465 Cluster: Phosphoribosylpyrophosphate synthetase;
n=11; cellular organisms|Rep:
Phosphoribosylpyrophosphate synthetase - Plasmodium
falciparum
Length = 323
Score = 61.3 bits (142), Expect = 3e-08
Identities = 27/59 (45%), Positives = 39/59 (66%)
Frame = +3
Query: 330 ETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVGVIPYLPYSKQ 506
E ++ +SIRGK++YIIQ VN N++ELL+M C+ +SA I VIPY Y++Q
Sbjct: 39 EVSMQFLESIRGKDVYIIQPTCPPVNENLIELLLMISTCRRASAKKITAVIPYYGYARQ 97
Score = 40.3 bits (90), Expect = 0.057
Identities = 26/72 (36%), Positives = 38/72 (52%), Gaps = 2/72 (2%)
Frame = +2
Query: 509 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFD--CPVDNLRASPFLLQYIPE 682
K+ R I + +A+M+ G+ ++ +DLH +IQGFF PVDNL A L Y +
Sbjct: 100 KLSSRVPISAADVARMIEAMGVDRVVAIDLHSGQIQGFFGPRVPVDNLEAQLIGLDYFTK 159
Query: 683 SIPDYRNSVIVA 718
D VIV+
Sbjct: 160 K--DLYKPVIVS 169
>UniRef50_Q8R753 Cluster: Ribose-phosphate pyrophosphokinase; n=18;
Bacteria|Rep: Ribose-phosphate pyrophosphokinase -
Thermoanaerobacter tengcongensis
Length = 316
Score = 61.3 bits (142), Expect = 3e-08
Identities = 29/59 (49%), Positives = 41/59 (69%)
Frame = +3
Query: 330 ETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVGVIPYLPYSKQ 506
E V I +S+RG ++++IQ+ VNNN+MELLIM A K +SA+ I VIPY Y++Q
Sbjct: 43 EISVRIGESVRGASVFVIQSTCAPVNNNLMELLIMIDAFKRASAAEINAVIPYYGYARQ 101
Score = 55.2 bits (127), Expect = 2e-06
Identities = 23/55 (41%), Positives = 36/55 (65%)
Frame = +2
Query: 509 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQY 673
K + R I +KL+A ++ +G ++TMDLH +IQG+F+ PVD+L P L +Y
Sbjct: 104 KAKARDPITAKLVADLITAAGAHRVVTMDLHAPQIQGYFNIPVDHLLGGPILAKY 158
>UniRef50_Q6MW31 Cluster: Related to ribose-phosphate
pyrophosphokinase II; n=3; Sordariales|Rep: Related to
ribose-phosphate pyrophosphokinase II - Neurospora
crassa
Length = 501
Score = 60.9 bits (141), Expect = 4e-08
Identities = 27/59 (45%), Positives = 39/59 (66%)
Frame = +2
Query: 542 LLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIPESIPDYRNSVIVA 718
L+A ++ +G I+T DLH+ QGFFD PVD+L A P L +YI I +Y+ +VIV+
Sbjct: 266 LIADLLTCAGADRIVTCDLHESTYQGFFDIPVDHLIARPLLKRYIQHHIENYKEAVIVS 324
Score = 46.4 bits (105), Expect = 9e-04
Identities = 20/41 (48%), Positives = 27/41 (65%)
Frame = +3
Query: 384 QTGTKDVNNNIMELLIMAYACKTSSASSIVGVIPYLPYSKQ 506
+TG VN+ +EL IM ACKT SA + V+P+ PYS+Q
Sbjct: 88 ETGHVTVNDYFIELCIMISACKTGSARRVTAVLPFFPYSRQ 128
Score = 33.5 bits (73), Expect = 6.6
Identities = 16/28 (57%), Positives = 19/28 (67%)
Frame = +3
Query: 330 ETIVEIADSIRGKNIYIIQTGTKDVNNN 413
ET EI DSIRGK++YIIQ+ N N
Sbjct: 40 ETRCEIRDSIRGKDVYIIQSFGVGTNRN 67
>UniRef50_Q1GEV9 Cluster: Ribose-phosphate pyrophosphokinase; n=11;
Alphaproteobacteria|Rep: Ribose-phosphate
pyrophosphokinase - Silicibacter sp. (strain TM1040)
Length = 340
Score = 60.5 bits (140), Expect = 5e-08
Identities = 27/59 (45%), Positives = 42/59 (71%)
Frame = +3
Query: 330 ETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVGVIPYLPYSKQ 506
E VE+ +++RG++++IIQ + N+N+MELLI+A A + SSA I VIPY Y++Q
Sbjct: 48 EIFVEVYENVRGEDMFIIQPTSNPANDNLMELLIIADALRRSSAQRITAVIPYFGYARQ 106
Score = 60.5 bits (140), Expect = 5e-08
Identities = 27/69 (39%), Positives = 42/69 (60%)
Frame = +2
Query: 509 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIPESI 688
+ + R I +K++A M+ +G+ ++TMDLH +IQGFFD PVDNL ASP +
Sbjct: 109 RTKARTPISAKMVANMLTGAGIERVLTMDLHAAQIQGFFDIPVDNLYASPIFALDVKAQF 168
Query: 689 PDYRNSVIV 715
D + ++V
Sbjct: 169 KDQMDDLMV 177
>UniRef50_A4T068 Cluster: Ribose-phosphate pyrophosphokinase; n=20;
Bacteria|Rep: Ribose-phosphate pyrophosphokinase -
Polynucleobacter sp. QLW-P1DMWA-1
Length = 321
Score = 60.5 bits (140), Expect = 5e-08
Identities = 28/59 (47%), Positives = 41/59 (69%)
Frame = +3
Query: 330 ETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVGVIPYLPYSKQ 506
E VEI +++RGKN+ +IQ+ N+++MEL+IM A K +SAS I VIPY Y++Q
Sbjct: 44 EIQVEIQENVRGKNVVVIQSTCAPTNDSLMELMIMIDALKRASASRITAVIPYFGYARQ 102
Score = 54.8 bits (126), Expect = 2e-06
Identities = 25/50 (50%), Positives = 36/50 (72%), Gaps = 1/50 (2%)
Frame = +2
Query: 521 RGCIVSKLLAQMMCK-SGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLL 667
R I ++++A M+ +G+ ++TMDLH +IQGFFD PVDN+ ASP LL
Sbjct: 110 RVAISARIVANMLQSVAGIERVLTMDLHADQIQGFFDIPVDNIYASPVLL 159
>UniRef50_Q75JN8 Cluster: Similar to ribose-phosphate
pyrophosphokinase; n=3; Dictyostelium discoideum|Rep:
Similar to ribose-phosphate pyrophosphokinase -
Dictyostelium discoideum (Slime mold)
Length = 329
Score = 60.5 bits (140), Expect = 5e-08
Identities = 29/76 (38%), Positives = 45/76 (59%), Gaps = 1/76 (1%)
Frame = +2
Query: 509 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYI-PES 685
K + R I KL+A MM +G+ +ITMDLH +IQGFF+ PV+N+ P ++YI +
Sbjct: 103 KDKSRAPITCKLVANMMEAAGIDRVITMDLHSSQIQGFFNIPVENVYTEPLFVKYIKKKK 162
Query: 686 IPDYRNSVIVARNPAL 733
++ N V +P +
Sbjct: 163 KTEFLNQEFVIVSPGV 178
Score = 52.4 bits (120), Expect = 1e-05
Identities = 29/73 (39%), Positives = 42/73 (57%), Gaps = 1/73 (1%)
Frame = +3
Query: 297 GGCSVYHKTNRETIVEIADSIRGKNIYIIQ-TGTKDVNNNIMELLIMAYACKTSSASSIV 473
G V N ET V I +S+R ++YI+Q T VN+ +MELL+M K +SA I
Sbjct: 30 GNALVSKFANSETQVIINESVRDVDLYIVQPTCNPSVNDYLMELLVMVDGAKRASAHRIT 89
Query: 474 GVIPYLPYSKQ*K 512
V+P+ Y++Q K
Sbjct: 90 AVVPFFGYARQSK 102
>UniRef50_A4EBQ1 Cluster: Putative uncharacterized protein; n=1;
Collinsella aerofaciens ATCC 25986|Rep: Putative
uncharacterized protein - Collinsella aerofaciens ATCC
25986
Length = 328
Score = 60.1 bits (139), Expect = 7e-08
Identities = 30/70 (42%), Positives = 45/70 (64%)
Frame = +2
Query: 509 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIPESI 688
K R I ++L+A ++ ++G+ IIT+DLHQ +IQGFFD PV++L A P QY +
Sbjct: 113 KAGPREPITARLVANLLERAGVDRIITLDLHQGQIQGFFDIPVNHLSALPLFGQYYNDMH 172
Query: 689 PDYRNSVIVA 718
D N V+V+
Sbjct: 173 FDTDNLVVVS 182
Score = 45.6 bits (103), Expect = 0.002
Identities = 25/74 (33%), Positives = 42/74 (56%), Gaps = 1/74 (1%)
Frame = +3
Query: 288 VRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQT-GTKDVNNNIMELLIMAYACKTSSAS 464
V G ++ N E +++RG ++++IQ+ +VN+ +MELLI A K +SA
Sbjct: 37 VELSGLTLKQFANGEIYARYDETVRGADVFLIQSVAGGNVNDMLMELLIATDAAKRASAR 96
Query: 465 SIVGVIPYLPYSKQ 506
SI VI + Y++Q
Sbjct: 97 SITAVITHYGYARQ 110
>UniRef50_Q8D2K5 Cluster: PrsA protein; n=1; Wigglesworthia
glossinidia endosymbiont of Glossina brevipalpis|Rep:
PrsA protein - Wigglesworthia glossinidia brevipalpis
Length = 305
Score = 59.7 bits (138), Expect = 9e-08
Identities = 28/59 (47%), Positives = 42/59 (71%)
Frame = +3
Query: 330 ETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVGVIPYLPYSKQ 506
E ++I +++RG+ ++IIQ+ VN+N MEL+I A A K +SA I+ VIPYL YS+Q
Sbjct: 36 EINIKINENVRGEEVFIIQSMCFPVNDNFMELVITADALKRASAKKIIAVIPYLGYSRQ 94
Score = 46.0 bits (104), Expect = 0.001
Identities = 17/39 (43%), Positives = 30/39 (76%)
Frame = +2
Query: 530 IVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNL 646
I +K++A ++ SG+ H+I +DLH ++IQGFFD +D++
Sbjct: 105 ITAKMIANLLAASGICHVIIVDLHCEQIQGFFDIILDSI 143
>UniRef50_Q8Y9L8 Cluster: Ribose-phosphate pyrophosphokinase 2;
n=15; Bacilli|Rep: Ribose-phosphate pyrophosphokinase 2
- Listeria monocytogenes
Length = 311
Score = 59.7 bits (138), Expect = 9e-08
Identities = 28/70 (40%), Positives = 48/70 (68%)
Frame = +2
Query: 509 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIPESI 688
K R R I +KL+A ++ ++G + +IT+DLH +IQGFF+ P+D+L A P + Y+ E+
Sbjct: 101 KARSREPITAKLMANLIQRAGANRLITVDLHAAQIQGFFNIPIDHLSAIPLIGDYLIENY 160
Query: 689 PDYRNSVIVA 718
+ ++ V+VA
Sbjct: 161 GE-KDVVVVA 169
Score = 55.6 bits (128), Expect = 1e-06
Identities = 26/59 (44%), Positives = 38/59 (64%)
Frame = +3
Query: 330 ETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVGVIPYLPYSKQ 506
E + I +SIRG N Y++Q+ +VN +MELLIM A K +S SI ++PY Y++Q
Sbjct: 40 EVKINIEESIRGTNAYVVQSMNSNVNERLMELLIMVDALKRASVHSINIIMPYYGYARQ 98
>UniRef50_Q83GR1 Cluster: Ribose-phosphate pyrophosphokinase; n=3;
Actinomycetales|Rep: Ribose-phosphate pyrophosphokinase
- Tropheryma whipplei (strain Twist) (Whipple's
bacillus)
Length = 348
Score = 59.3 bits (137), Expect = 1e-07
Identities = 26/65 (40%), Positives = 41/65 (63%)
Frame = +3
Query: 324 NRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVGVIPYLPYSK 503
N E S+RGK+++++QTG VN+ ++ELL++ +CK +SA I V P PYS+
Sbjct: 67 NGEIYTRFNSSVRGKDVFVLQTGCDPVNDGLVELLLLIDSCKRASAKHISAVTPCYPYSR 126
Query: 504 Q*KCG 518
Q + G
Sbjct: 127 QDRKG 131
Score = 50.0 bits (114), Expect = 7e-05
Identities = 21/49 (42%), Positives = 35/49 (71%)
Frame = +2
Query: 530 IVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYI 676
I ++L+A ++ +G IIT+DLH +IQGFF+ PVD+L P L++++
Sbjct: 137 ISARLVADLIACAGADRIITVDLHASQIQGFFNGPVDHLTGVPALIKHV 185
>UniRef50_Q822W0 Cluster: Ribose-phosphate pyrophosphokinase; n=2;
Chlamydophila|Rep: Ribose-phosphate pyrophosphokinase -
Chlamydophila caviae
Length = 301
Score = 59.3 bits (137), Expect = 1e-07
Identities = 28/78 (35%), Positives = 48/78 (61%)
Frame = +3
Query: 273 CQPPRVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKT 452
C +++ G + + ET V++ + +RG++++I+Q+ N+ + ELLI+A A K
Sbjct: 21 CAELKIKLGRMELNQFPDGETHVKVLEDVRGRDVFIMQSIVGQPNHYLFELLIIADALKR 80
Query: 453 SSASSIVGVIPYLPYSKQ 506
SSA SI +IPYL Y +Q
Sbjct: 81 SSAKSITAIIPYLGYCRQ 98
Score = 42.3 bits (95), Expect = 0.014
Identities = 18/53 (33%), Positives = 32/53 (60%)
Frame = +2
Query: 530 IVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIPESI 688
I +KL+A ++ +G++++IT DLH +I+GF+ VD+L + I I
Sbjct: 108 ITAKLVADVLTTAGITNLITCDLHADQIEGFYKTHVDHLHCQQLFVDTIKSCI 160
>UniRef50_Q42581 Cluster: Ribose-phosphate pyrophosphokinase 1;
n=145; cellular organisms|Rep: Ribose-phosphate
pyrophosphokinase 1 - Arabidopsis thaliana (Mouse-ear
cress)
Length = 403
Score = 59.3 bits (137), Expect = 1e-07
Identities = 25/69 (36%), Positives = 42/69 (60%)
Frame = +3
Query: 297 GGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVG 476
G ++ + E V++ +S+RG ++Y++Q N N+MELLIM AC+ +SA +
Sbjct: 117 GKVNIKRFADGEIYVQLQESVRGCDVYLVQPTCTPTNENLMELLIMVDACRRASAKKVTA 176
Query: 477 VIPYLPYSK 503
VIPY Y++
Sbjct: 177 VIPYFGYAR 185
Score = 51.6 bits (118), Expect = 2e-05
Identities = 30/90 (33%), Positives = 48/90 (53%), Gaps = 7/90 (7%)
Frame = +2
Query: 509 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYI-PES 685
K + R I +KL+A ++ ++G ++ DLH + G+FD PVD++ P +L Y+ +S
Sbjct: 189 KTQGRESIAAKLVANLITEAGADRVLACDLHSGQSMGYFDIPVDHVYCQPVILDYLASKS 248
Query: 686 IPDYRNSVI------VARNPALQRKLLHMP 757
IP V+ VAR A +KL P
Sbjct: 249 IPSEDLVVVSPDVGGVARARAFAKKLSDAP 278
>UniRef50_Q74LT0 Cluster: Phosphoribosylpyrophosphate synthetase;
n=5; Lactobacillus|Rep: Phosphoribosylpyrophosphate
synthetase - Lactobacillus johnsonii
Length = 329
Score = 58.8 bits (136), Expect = 2e-07
Identities = 29/67 (43%), Positives = 44/67 (65%)
Frame = +3
Query: 306 SVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVGVIP 485
+V H ++ E V I +S+RG ++Y+IQ+ VN N MEL+I+ A +SA S+ VIP
Sbjct: 40 AVQHFSDGEIQVNITESVRGCDVYVIQSIQDPVNENFMELMIVLDALHRASAHSVNVVIP 99
Query: 486 YLPYSKQ 506
Y+ YS+Q
Sbjct: 100 YMAYSRQ 106
Score = 57.6 bits (133), Expect = 4e-07
Identities = 29/74 (39%), Positives = 43/74 (58%), Gaps = 1/74 (1%)
Frame = +2
Query: 509 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQY-IPES 685
K R R I +KLLA ++ + + +I +DLH +IQGF++ PVD+L A P L QY +
Sbjct: 109 KNRSREPITAKLLANLLQLTDIDDLIAVDLHASQIQGFYNIPVDHLHAMPILAQYFLDNG 168
Query: 686 IPDYRNSVIVARNP 727
I N +V +P
Sbjct: 169 IASKENDDVVVVSP 182
>UniRef50_A5URX1 Cluster: Ribose-phosphate pyrophosphokinase; n=3;
Bacteria|Rep: Ribose-phosphate pyrophosphokinase -
Roseiflexus sp. RS-1
Length = 315
Score = 58.8 bits (136), Expect = 2e-07
Identities = 26/72 (36%), Positives = 42/72 (58%)
Frame = +3
Query: 288 VRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASS 467
V G C V + V I +++RG+++YI+Q+ N+N MELL A K +SA+S
Sbjct: 27 VTPGQCEVLRFSEGNLFVRILENVRGRHVYIVQSTAYPANDNFMELLFWIDAFKRASAAS 86
Query: 468 IVGVIPYLPYSK 503
+ V+P+ Y+K
Sbjct: 87 VTAVVPFFSYAK 98
Score = 46.8 bits (106), Expect = 7e-04
Identities = 26/78 (33%), Positives = 41/78 (52%)
Frame = +2
Query: 509 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIPESI 688
K R I +++ A + +G I+ MDLH +IQGFF PVD+L A P L + +
Sbjct: 102 KDEPRVSIRARVCADAIEAAGADRIVVMDLHAPQIQGFFKIPVDDLYALPVLCDRVRQM- 160
Query: 689 PDYRNSVIVARNPALQRK 742
+ N ++VA + +K
Sbjct: 161 -NLENLIVVAPDSGFAKK 177
>UniRef50_UPI0000EB04C8 Cluster: UPI0000EB04C8 related cluster; n=1;
Canis lupus familiaris|Rep: UPI0000EB04C8 UniRef100
entry - Canis familiaris
Length = 298
Score = 58.4 bits (135), Expect = 2e-07
Identities = 30/69 (43%), Positives = 43/69 (62%)
Frame = +2
Query: 509 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIPESI 688
K + I +K +A M+ +G HIITMDLH ++QGFF+ PVDNL P +L E+I
Sbjct: 102 KDKSHALISAKPVANML--AGADHIITMDLHDSQVQGFFNIPVDNLSVEPAIL----ENI 155
Query: 689 PDYRNSVIV 715
+RN +I+
Sbjct: 156 AKWRNCIII 164
Score = 56.0 bits (129), Expect = 1e-06
Identities = 24/60 (40%), Positives = 41/60 (68%)
Frame = +3
Query: 321 TNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVGVIPYLPYS 500
+N+ET +E++ + +GK++Y IQ+G ++ NN+M L IM K +++S + VIP PYS
Sbjct: 37 SNQETSLEVSGNRKGKDVYNIQSGYGEIKNNLMGLFIMINTDKITASSRVTSVIPCFPYS 96
>UniRef50_Q6F241 Cluster: Ribose-phosphate pyrophosphokinase; n=6;
Mollicutes|Rep: Ribose-phosphate pyrophosphokinase -
Mesoplasma florum (Acholeplasma florum)
Length = 347
Score = 58.4 bits (135), Expect = 2e-07
Identities = 29/59 (49%), Positives = 39/59 (66%)
Frame = +3
Query: 330 ETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVGVIPYLPYSKQ 506
E ++E DS+RGK I++IQ+ + VN +IMELLI A K SA I VIPY Y++Q
Sbjct: 43 EILIESLDSVRGKEIFVIQSTSTPVNESIMELLIAIDAFKRGSAEKINVVIPYYGYARQ 101
Score = 47.6 bits (108), Expect = 4e-04
Identities = 21/60 (35%), Positives = 36/60 (60%)
Frame = +2
Query: 509 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIPESI 688
K + R I SKL+A ++ K+G ++++D+H + GFFD P+DN + L I ++I
Sbjct: 104 KAKGRQPITSKLVADLLTKAGADRVMSIDIHSPQSMGFFDVPMDNFYTAQTLATEIIDTI 163
>UniRef50_UPI00005A2C8C Cluster: PREDICTED: similar to
Ribose-phosphate pyrophosphokinase I (Phosphoribosyl
pyrophosphate synthetase I) (PRS-I); n=1; Canis lupus
familiaris|Rep: PREDICTED: similar to Ribose-phosphate
pyrophosphokinase I (Phosphoribosyl pyrophosphate
synthetase I) (PRS-I) - Canis familiaris
Length = 339
Score = 58.0 bits (134), Expect = 3e-07
Identities = 27/64 (42%), Positives = 42/64 (65%)
Frame = +3
Query: 321 TNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVGVIPYLPYS 500
+++ET VE+ S RG++ Y +Q+G ++ +MELLIM CK +SA + VIP PY+
Sbjct: 78 SDQETCVEMGKSERGEDNYTVQSGCGHTSDGLMELLIMINTCKIASAHWVTAVIPCFPYA 137
Query: 501 KQ*K 512
+Q K
Sbjct: 138 RQGK 141
Score = 54.8 bits (126), Expect = 2e-06
Identities = 23/43 (53%), Positives = 33/43 (76%)
Frame = +2
Query: 590 MDLHQKEIQGFFDCPVDNLRASPFLLQYIPESIPDYRNSVIVA 718
+DLH +IQGFFD PVD++RA P +L+ I ESI ++RN +V+
Sbjct: 151 LDLHTSQIQGFFDIPVDHVRAEPAVLKCIRESISEWRNCTVVS 193
>UniRef50_Q6Z2L5-2 Cluster: Isoform 2 of Q6Z2L5 ; n=1; Oryza sativa
(japonica cultivar-group)|Rep: Isoform 2 of Q6Z2L5 -
Oryza sativa subsp. japonica (Rice)
Length = 365
Score = 58.0 bits (134), Expect = 3e-07
Identities = 25/69 (36%), Positives = 43/69 (62%)
Frame = +3
Query: 297 GGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVG 476
G ++ + E V++ +S+RG +++++Q N N+MELLIM AC+ +SA +I
Sbjct: 104 GKINIKRFADGEIYVQLQESVRGCDVFLVQPTCPPANENLMELLIMIDACRRASAKNITA 163
Query: 477 VIPYLPYSK 503
VIPY Y++
Sbjct: 164 VIPYFGYAR 172
>UniRef50_Q6MAT0 Cluster: Probable phosphoribosyl pyrophosphate
synthetase; n=1; Candidatus Protochlamydia amoebophila
UWE25|Rep: Probable phosphoribosyl pyrophosphate
synthetase - Protochlamydia amoebophila (strain UWE25)
Length = 313
Score = 58.0 bits (134), Expect = 3e-07
Identities = 26/63 (41%), Positives = 43/63 (68%)
Frame = +2
Query: 530 IVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIPESIPDYRNSV 709
I +KL+A ++ ++G++ I+TMDLH ++QGFFD PVD+L L+ + + D NS+
Sbjct: 110 ITAKLVANLLVEAGITRILTMDLHVDQLQGFFDIPVDHLSGRQLLIDELQKL--DLTNSI 167
Query: 710 IVA 718
+VA
Sbjct: 168 VVA 170
Score = 54.4 bits (125), Expect = 3e-06
Identities = 34/101 (33%), Positives = 56/101 (55%)
Frame = +3
Query: 228 LLF*VETHI*IS*FDCQPPRVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVN 407
LLF +H ++ Q ++ G + + E V++ +S+RGK+ +++Q+ D N
Sbjct: 8 LLFAGSSHPILATEIAQQLKISLGQMQLSKFPDGEIGVQLLESVRGKDTFVLQSIALDPN 67
Query: 408 NNIMELLIMAYACKTSSASSIVGVIPYLPYSKQ*KCGNEDV 530
+MELLI+ A K +SA +IV VIPY Y +Q + DV
Sbjct: 68 FYLMELLIIVDALKRASARNIVAVIPYYGYCRQDRKDKFDV 108
>UniRef50_Q8G5P2 Cluster: Ribose-phosphate pyrophosphokinase; n=56;
Bacteria|Rep: Ribose-phosphate pyrophosphokinase -
Bifidobacterium longum
Length = 340
Score = 57.2 bits (132), Expect = 5e-07
Identities = 29/69 (42%), Positives = 41/69 (59%)
Frame = +3
Query: 306 SVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVGVIP 485
+ Y N E V +S+RG +++++Q+ K +N IME LIM A K +SA SI V P
Sbjct: 41 TAYDFANGEMYVRYTESVRGADVFVLQSHYKPINKAIMEQLIMIDALKRASARSITAVCP 100
Query: 486 YLPYSKQ*K 512
L YS+Q K
Sbjct: 101 LLGYSRQDK 109
Score = 51.2 bits (117), Expect = 3e-05
Identities = 26/69 (37%), Positives = 41/69 (59%)
Frame = +2
Query: 509 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIPESI 688
K R R I +L+ ++ +G I+++DLH + QGFFD PVD+L A P L+ YI +
Sbjct: 110 KHRGREPISCRLVFDLLKTAGADRIMSVDLHAAQSQGFFDGPVDHLVAMPVLVDYIRDRF 169
Query: 689 PDYRNSVIV 715
+ ++V V
Sbjct: 170 QGHLDNVAV 178
>UniRef50_Q075L4 Cluster: Plastid ribose-phosphate diphosphokinase;
n=1; Prototheca wickerhamii|Rep: Plastid
ribose-phosphate diphosphokinase - Prototheca
wickerhamii
Length = 213
Score = 56.8 bits (131), Expect = 6e-07
Identities = 26/69 (37%), Positives = 43/69 (62%)
Frame = +3
Query: 297 GGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVG 476
G S+ + E V++ +SIRG ++++IQ VN+ ++ELLI AC+ +SA SI
Sbjct: 142 GAISIKRFADGEIYVQVGESIRGCDVFLIQPTAPPVNDALVELLITIDACRRASARSITA 201
Query: 477 VIPYLPYSK 503
V+PY Y++
Sbjct: 202 VLPYFGYAR 210
>UniRef50_Q8IE40 Cluster: Ribose-phosphate pyrophosphokinase,
putative; n=4; Plasmodium|Rep: Ribose-phosphate
pyrophosphokinase, putative - Plasmodium falciparum
(isolate 3D7)
Length = 560
Score = 56.8 bits (131), Expect = 6e-07
Identities = 28/64 (43%), Positives = 41/64 (64%), Gaps = 3/64 (4%)
Frame = +3
Query: 330 ETIVEIADSIRGKNIYIIQT---GTKDVNNNIMELLIMAYACKTSSASSIVGVIPYLPYS 500
E ++I D +RG++IYII + G KDV++ +MEL + + SSA + VIPYL YS
Sbjct: 211 EIALQIMDEVRGRDIYIIHSTPAGGKDVHSRLMELFLFISTLRRSSAKKVTAVIPYLNYS 270
Query: 501 KQ*K 512
+Q K
Sbjct: 271 RQTK 274
>UniRef50_Q9RUD2 Cluster: Probable ribose-phosphate
pyrophosphokinase; n=7; Bacteria|Rep: Probable
ribose-phosphate pyrophosphokinase - Deinococcus
radiodurans
Length = 320
Score = 56.8 bits (131), Expect = 6e-07
Identities = 23/63 (36%), Positives = 39/63 (61%)
Frame = +2
Query: 530 IVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIPESIPDYRNSV 709
I +L+A ++ ++G ++TM LH ++ GFF PVD+L A L Q+ + +PD N V
Sbjct: 111 IAGRLVADLLQEAGADRVLTMTLHSPQVHGFFKVPVDHLSADVVLSQHFKKCVPDAHNGV 170
Query: 710 IVA 718
++A
Sbjct: 171 VLA 173
Score = 53.2 bits (122), Expect = 8e-06
Identities = 25/64 (39%), Positives = 41/64 (64%)
Frame = +3
Query: 321 TNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVGVIPYLPYS 500
TN IV +S+R +++I+QT + V++ IMEL++M A K++SA + VIPY Y+
Sbjct: 40 TNDNLIVHYEESLREGDVFIVQTFSTPVSDAIMELMLMIDAAKSASAGRVTAVIPYYSYA 99
Query: 501 KQ*K 512
+ K
Sbjct: 100 RSDK 103
>UniRef50_Q89DJ1 Cluster: Ribose-phosphate pyrophosphokinase; n=310;
Bacteria|Rep: Ribose-phosphate pyrophosphokinase -
Bradyrhizobium japonicum
Length = 317
Score = 56.8 bits (131), Expect = 6e-07
Identities = 26/68 (38%), Positives = 43/68 (63%)
Frame = +2
Query: 509 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIPESI 688
K R I +KL+A ++ ++G+ ++T+DLH +IQGFFD P DNL A+P +++ I +
Sbjct: 104 KSGSRTPISAKLVANLITQAGVDRVMTLDLHAGQIQGFFDIPTDNLYAAPLMVRDIKDKF 163
Query: 689 PDYRNSVI 712
+ VI
Sbjct: 164 DLSKTMVI 171
Score = 54.8 bits (126), Expect = 2e-06
Identities = 25/59 (42%), Positives = 40/59 (67%)
Frame = +3
Query: 330 ETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVGVIPYLPYSKQ 506
E VEI +++RG + +IIQ+ + N+++MELLI+ A + SSA I V+PY Y++Q
Sbjct: 43 EIFVEIQENVRGSDAFIIQSTSFPANDHLMELLIITDALRRSSARRITAVLPYFGYARQ 101
>UniRef50_Q03YB5 Cluster: Ribose-phosphate pyrophosphokinase; n=2;
Lactobacillales|Rep: Ribose-phosphate pyrophosphokinase
- Leuconostoc mesenteroides subsp. mesenteroides (strain
ATCC 8293 /NCDO 523)
Length = 323
Score = 56.4 bits (130), Expect = 8e-07
Identities = 25/55 (45%), Positives = 36/55 (65%)
Frame = +2
Query: 509 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQY 673
K R R I ++++A M+ G+ ++TMDLH ++QGFFD PVD+L A P L Y
Sbjct: 101 KARSREPISARMIANMLESQGVKRVMTMDLHADQVQGFFDIPVDHLLAMPALGHY 155
Score = 53.6 bits (123), Expect = 6e-06
Identities = 24/60 (40%), Positives = 40/60 (66%)
Frame = +3
Query: 324 NRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVGVIPYLPYSK 503
+ E I +++RG+N+Y+IQ T VN+N M+L+I A + +SA+SI +IPY Y++
Sbjct: 38 DNEIYERIENTVRGRNVYVIQGITAPVNDNFMKLMIFIDAARRASANSINVIIPYFGYAR 97
>UniRef50_Q4XQD5 Cluster: Ribose-phosphate pyrophosphokinase,
putative; n=1; Plasmodium chabaudi|Rep: Ribose-phosphate
pyrophosphokinase, putative - Plasmodium chabaudi
Length = 465
Score = 56.4 bits (130), Expect = 8e-07
Identities = 28/83 (33%), Positives = 48/83 (57%), Gaps = 3/83 (3%)
Frame = +3
Query: 273 CQPPRVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQT---GTKDVNNNIMELLIMAYA 443
C + G + ++ E ++I D +RG+++YII + G KDV++ +MEL +
Sbjct: 119 CSNLGISLGRAYIGKYSDGEITLQIMDEVRGRDVYIIHSTPAGGKDVHSRLMELFLFVST 178
Query: 444 CKTSSASSIVGVIPYLPYSKQ*K 512
+ SSA ++ V+PYL YS+Q K
Sbjct: 179 LRRSSAKKVIVVLPYLNYSRQNK 201
>UniRef50_P75044 Cluster: Ribose-phosphate pyrophosphokinase; n=6;
Mycoplasma|Rep: Ribose-phosphate pyrophosphokinase -
Mycoplasma pneumoniae
Length = 328
Score = 56.4 bits (130), Expect = 8e-07
Identities = 27/78 (34%), Positives = 45/78 (57%)
Frame = +3
Query: 273 CQPPRVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKT 452
CQ ++ G + + ET + +S+R K+++I Q+ VN+++MELLI A K
Sbjct: 22 CQKLKMPMGLITHNEFADGETYIRFEESVRNKDVFIFQSTCAPVNDSLMELLIAIDALKR 81
Query: 453 SSASSIVGVIPYLPYSKQ 506
SA SI ++PY Y++Q
Sbjct: 82 GSAKSITAILPYYGYARQ 99
Score = 45.2 bits (102), Expect = 0.002
Identities = 20/47 (42%), Positives = 29/47 (61%)
Frame = +2
Query: 509 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLR 649
K R I SKL+A ++ +G+S + D+H + QGFF+ PVD LR
Sbjct: 102 KTMGREPITSKLVADLLTTAGVSRVALTDIHSDQTQGFFNIPVDTLR 148
>UniRef50_Q0G092 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Fulvimarina pelagi HTCC2506|Rep: Ribose-phosphate
pyrophosphokinase - Fulvimarina pelagi HTCC2506
Length = 307
Score = 56.0 bits (129), Expect = 1e-06
Identities = 24/70 (34%), Positives = 46/70 (65%)
Frame = +3
Query: 297 GGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVG 476
G V ++E VEI +++RG++++++Q+ + N+++MELLI+ A + +SA I
Sbjct: 10 GEALVRRFADQEIFVEIQENVRGEDVFVVQSTSYPANDHLMELLIIIDAMRRASARRITA 69
Query: 477 VIPYLPYSKQ 506
V+PY Y++Q
Sbjct: 70 VLPYFGYARQ 79
Score = 52.8 bits (121), Expect = 1e-05
Identities = 26/63 (41%), Positives = 38/63 (60%)
Frame = +2
Query: 530 IVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIPESIPDYRNSV 709
I +KL+A ++ +G ++T+DLH +IQGFFD P DNL A P + I E D N
Sbjct: 89 ISAKLVANLITHAGADRVMTLDLHAGQIQGFFDIPTDNLFAIPLFARDIKEH-QDLSNLT 147
Query: 710 IVA 718
+V+
Sbjct: 148 VVS 150
>UniRef50_A5V1W5 Cluster: Ribose-phosphate pyrophosphokinase; n=5;
Chloroflexi (class)|Rep: Ribose-phosphate
pyrophosphokinase - Roseiflexus sp. RS-1
Length = 327
Score = 56.0 bits (129), Expect = 1e-06
Identities = 24/77 (31%), Positives = 44/77 (57%)
Frame = +3
Query: 273 CQPPRVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKT 452
C VR G ++ N V + +S+R K++++IQ+ +++ I+ELLIM AC+
Sbjct: 24 CNRLGVRLGDVTITRFANENIFVRLNESVREKDVFVIQSLASPLSDRILELLIMLDACRR 83
Query: 453 SSASSIVGVIPYLPYSK 503
+SA + V+P+ Y +
Sbjct: 84 ASAGRVTAVVPFYAYGR 100
Score = 48.4 bits (110), Expect = 2e-04
Identities = 21/48 (43%), Positives = 31/48 (64%)
Frame = +2
Query: 530 IVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQY 673
I ++LLA M+ +G ++T+DLH +IQGFF PVD L L++Y
Sbjct: 111 ITARLLADMIQVAGAQQLVTIDLHAGQIQGFFSIPVDELSCMGLLVRY 158
>UniRef50_Q4Q0M2 Cluster: Phosphoribosylpyrophosphate synthetase,
putative; n=6; Trypanosomatidae|Rep:
Phosphoribosylpyrophosphate synthetase, putative -
Leishmania major
Length = 358
Score = 55.2 bits (127), Expect = 2e-06
Identities = 30/67 (44%), Positives = 45/67 (67%), Gaps = 6/67 (8%)
Frame = +3
Query: 324 NRETIVEIADSIRGKNIYIIQ------TGTKDVNNNIMELLIMAYACKTSSASSIVGVIP 485
N ETIV+I +SIRG +I++IQ GT +VN +MELL++ + K SSA ++ VIP
Sbjct: 44 NGETIVKILESIRGDDIFVIQPTCSNSAGT-NVNQAVMELLLIIHTLKLSSARRVIAVIP 102
Query: 486 YLPYSKQ 506
+ Y++Q
Sbjct: 103 HYGYARQ 109
Score = 46.8 bits (106), Expect = 7e-04
Identities = 24/64 (37%), Positives = 39/64 (60%), Gaps = 1/64 (1%)
Frame = +2
Query: 530 IVSKLLAQMMCKSGLSHIITMDLHQKEIQGFF-DCPVDNLRASPFLLQYIPESIPDYRNS 706
I + +A+M+ + G++ ++TMDLH +IQGFF CPV +L S +Y+ + N
Sbjct: 119 ISASAVARMVTEMGVNGVVTMDLHCGQIQGFFHGCPVADLSPSSEFAEYVKQKNFTPNNL 178
Query: 707 VIVA 718
V+VA
Sbjct: 179 VVVA 182
>UniRef50_Q3M5L4 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Anabaena variabilis ATCC 29413|Rep: Ribose-phosphate
pyrophosphokinase - Anabaena variabilis (strain ATCC
29413 / PCC 7937)
Length = 310
Score = 54.0 bits (124), Expect = 4e-06
Identities = 24/69 (34%), Positives = 44/69 (63%)
Frame = +3
Query: 297 GGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVG 476
G +V + E V + +S+R K+++I+Q+ VN++++ELL A AC+ ++AS I
Sbjct: 28 GKSAVERFPDGEVNVRLLESVRQKSVFILQSTAPPVNDHLVELLAFADACRRAAASRITA 87
Query: 477 VIPYLPYSK 503
+IPY Y++
Sbjct: 88 IIPYFGYAR 96
Score = 52.4 bits (120), Expect = 1e-05
Identities = 24/67 (35%), Positives = 43/67 (64%)
Frame = +2
Query: 518 KRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIPESIPDY 697
+R I + ++A+++ G++H++T+DLH +I+GFF PVD+L A P + I +P
Sbjct: 103 RREPITASMVAEVLQAVGVNHVVTLDLHTLQIEGFFRIPVDSLTAVPIFCEAIRHYLPP- 161
Query: 698 RNSVIVA 718
N V+V+
Sbjct: 162 -NFVVVS 167
>UniRef50_Q4Q3Z4 Cluster: Phosphoribosylpyrophosphate synthetase,
putative; n=6; Trypanosomatidae|Rep:
Phosphoribosylpyrophosphate synthetase, putative -
Leishmania major
Length = 356
Score = 52.4 bits (120), Expect = 1e-05
Identities = 25/65 (38%), Positives = 39/65 (60%), Gaps = 4/65 (6%)
Frame = +3
Query: 324 NRETIVEIADSIRGKNIYIIQTGT----KDVNNNIMELLIMAYACKTSSASSIVGVIPYL 491
N E +++ D++RG + +IIQ DVN +MELL++ + K SSA I ++PY
Sbjct: 69 NGELNIKVVDNVRGDDCFIIQPTAGGFDTDVNTAMMELLLLVHTLKLSSAKRITAIVPYY 128
Query: 492 PYSKQ 506
YS+Q
Sbjct: 129 AYSRQ 133
Score = 44.0 bits (99), Expect = 0.005
Identities = 25/70 (35%), Positives = 37/70 (52%), Gaps = 1/70 (1%)
Frame = +2
Query: 509 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFF-DCPVDNLRASPFLLQYIPES 685
K R I + +AQ++ G+ ++TMDLH +IQGFF + PVDNL P Y+
Sbjct: 136 KSEPRVPISASAVAQLLQCMGVDRVVTMDLHCGQIQGFFRNIPVDNLLMFPEFATYLTRQ 195
Query: 686 IPDYRNSVIV 715
+N +V
Sbjct: 196 PWFDKNQTVV 205
>UniRef50_Q2GIZ1 Cluster: Ribose-phosphate pyrophosphokinase; n=6;
Anaplasmataceae|Rep: Ribose-phosphate pyrophosphokinase
- Anaplasma phagocytophilum (strain HZ)
Length = 322
Score = 51.6 bits (118), Expect = 2e-05
Identities = 20/50 (40%), Positives = 33/50 (66%)
Frame = +2
Query: 536 SKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIPES 685
+K++A+++ SGL HI+T+DLH ++ GFFD P N+ A + Y+ S
Sbjct: 116 AKVIARILSTSGLDHIVTLDLHSQQAAGFFDVPFTNISAYDVFVDYLSSS 165
>UniRef50_A0E424 Cluster: Chromosome undetermined scaffold_77, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_77,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 371
Score = 51.6 bits (118), Expect = 2e-05
Identities = 21/59 (35%), Positives = 38/59 (64%)
Frame = +3
Query: 330 ETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVGVIPYLPYSKQ 506
E +++ +++RG+N +IIQ+ VN N++EL + A + +S +I +IPY YS+Q
Sbjct: 80 ECNIQVLENVRGRNAFIIQSTCPPVNENLVELFLFISALRRASVKTITVIIPYYGYSRQ 138
Score = 40.3 bits (90), Expect = 0.057
Identities = 19/54 (35%), Positives = 37/54 (68%), Gaps = 2/54 (3%)
Frame = +2
Query: 509 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFF--DCPVDNLRASPFL 664
K+ K I + +A+++ ++G+ H++++DLH+ ++QG F PVDNL SP++
Sbjct: 141 KLAKTESIAAADIAKILEQTGIDHLVSIDLHRGQLQGAFSTSVPVDNL--SPYI 192
>UniRef50_Q8EUI1 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Mycoplasma penetrans|Rep: Ribose-phosphate
pyrophosphokinase - Mycoplasma penetrans
Length = 332
Score = 51.2 bits (117), Expect = 3e-05
Identities = 22/59 (37%), Positives = 39/59 (66%)
Frame = +3
Query: 330 ETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVGVIPYLPYSKQ 506
E +V+ ++RG ++++ Q+ VN+N+MELLI + K +SA +I +IPY Y++Q
Sbjct: 43 EILVKSNSTVRGMHVFLFQSTCNPVNDNLMELLIAIDSLKRASAKTITVIIPYFGYARQ 101
Score = 48.8 bits (111), Expect = 2e-04
Identities = 26/71 (36%), Positives = 40/71 (56%), Gaps = 1/71 (1%)
Frame = +2
Query: 509 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIPESI 688
K + R I KL+A + +G + +I +D+H ++ QGFFD PVD L AS L ++
Sbjct: 104 KAKGREPITCKLVANFLEGAGATKVILIDIHSEQTQGFFDIPVDTLTASCVLFNEFRKNN 163
Query: 689 PD-YRNSVIVA 718
P +N +VA
Sbjct: 164 PSVIKNLTVVA 174
>UniRef50_Q4UNC9 Cluster: Ribose-phosphate pyrophosphokinase; n=9;
Rickettsia|Rep: Ribose-phosphate pyrophosphokinase -
Rickettsia felis (Rickettsia azadi)
Length = 293
Score = 51.2 bits (117), Expect = 3e-05
Identities = 29/69 (42%), Positives = 43/69 (62%)
Frame = +2
Query: 512 MRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIPESIP 691
+ + I +KL+A + K G++H+IT+DLH +I+ FF+ P+ NL P L YIP +
Sbjct: 97 INSQNIIPAKLIADFLEKLGVNHVITIDLHSDKIEKFFNIPISNL--EPINL-YIP-FLR 152
Query: 692 DYRNSVIVA 718
Y N VIVA
Sbjct: 153 TYSNFVIVA 161
Score = 48.8 bits (111), Expect = 2e-04
Identities = 21/67 (31%), Positives = 43/67 (64%)
Frame = +3
Query: 330 ETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVGVIPYLPYSKQ* 509
E VEI +S +++ I+Q+ +K VN+ ++EL ++ A K + A+ I+ V+PY Y++Q
Sbjct: 36 EIKVEIQESFHNEDVIIVQSTSKPVNDRLIELFLLVDAAKKAVANRIILVMPYFGYARQD 95
Query: 510 KCGNEDV 530
++++
Sbjct: 96 NINSQNI 102
>UniRef50_Q9PQV0 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Ureaplasma parvum|Rep: Ribose-phosphate
pyrophosphokinase - Ureaplasma parvum (Ureaplasma
urealyticum biotype 1)
Length = 330
Score = 50.8 bits (116), Expect = 4e-05
Identities = 26/59 (44%), Positives = 39/59 (66%)
Frame = +3
Query: 330 ETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVGVIPYLPYSKQ 506
E IV +RG+ + IIQ+ +K VN+++MELLI + K +SA +I VIPY Y++Q
Sbjct: 42 ELIVAPQVPVRGRRVIIIQSTSKPVNDSLMELLIAIDSIKRASAKAISVVIPYYGYARQ 100
Score = 50.4 bits (115), Expect = 5e-05
Identities = 24/70 (34%), Positives = 42/70 (60%)
Frame = +2
Query: 509 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIPESI 688
K + R I ++L+A+M+ +G + ++T D+H + QGFFD P D+L A L+++ +
Sbjct: 103 KAKPREPITARLVAKMIESAGATSVLTWDIHSLQTQGFFDIPFDSLEAVWVLMKHYFSAY 162
Query: 689 PDYRNSVIVA 718
D N IV+
Sbjct: 163 KDSSNITIVS 172
>UniRef50_A7ARJ1 Cluster: Ribose-phosphate pyrophosphokinase,
putative; n=1; Babesia bovis|Rep: Ribose-phosphate
pyrophosphokinase, putative - Babesia bovis
Length = 339
Score = 50.4 bits (115), Expect = 5e-05
Identities = 26/78 (33%), Positives = 42/78 (53%)
Frame = +3
Query: 273 CQPPRVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKT 452
C + G V ++ E V++ + I G ++ IIQ+ + VN N++ELL M A +
Sbjct: 51 CSLSGLTLGKSDVSTFSDGEIKVDLQEEILGCDVVIIQSTSPPVNRNLIELLFMISAARK 110
Query: 453 SSASSIVGVIPYLPYSKQ 506
S A I +IPY Y++Q
Sbjct: 111 SGAKQITAIIPYFGYARQ 128
>UniRef50_Q98R83 Cluster: Ribose-phosphate pyrophosphokinase; n=10;
Mycoplasma|Rep: Ribose-phosphate pyrophosphokinase -
Mycoplasma pulmonis
Length = 321
Score = 50.4 bits (115), Expect = 5e-05
Identities = 23/52 (44%), Positives = 34/52 (65%)
Frame = +2
Query: 509 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFL 664
K R I +KLLA ++ +G+S I+ +DLH IQGFF+ PVD+++A L
Sbjct: 102 KAEGRQPIAAKLLADLLQVAGISRIVVVDLHNPSIQGFFNIPVDDIKAQYIL 153
Score = 46.4 bits (105), Expect = 9e-04
Identities = 19/59 (32%), Positives = 38/59 (64%)
Frame = +3
Query: 330 ETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVGVIPYLPYSKQ 506
E ++ +++R K+++I+ + + NNNIM+LLI + K +SA +I ++ Y Y++Q
Sbjct: 41 EVLLSSKETVRSKDVFIVASTSHPANNNIMDLLIFVDSLKRASAKTINVILSYYGYARQ 99
>UniRef50_Q4QI56 Cluster: Phosphoribosylpyrophosphate synthetase;
n=8; Trypanosomatidae|Rep: Phosphoribosylpyrophosphate
synthetase - Leishmania major
Length = 370
Score = 48.4 bits (110), Expect = 2e-04
Identities = 23/57 (40%), Positives = 37/57 (64%), Gaps = 1/57 (1%)
Frame = +2
Query: 509 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFD-CPVDNLRASPFLLQYI 676
K RG I + ++A+M+ K G++ + ++DLH +IQGFFD PVDNL + +Y+
Sbjct: 147 KTSLRGPISASVVARMVVKMGVNRLASLDLHSNQIQGFFDNIPVDNLLMAHEFARYL 203
Score = 46.4 bits (105), Expect = 9e-04
Identities = 25/71 (35%), Positives = 42/71 (59%), Gaps = 4/71 (5%)
Frame = +3
Query: 306 SVYHKTNRETIVEIADSIRGKNIYIIQ--TGTK--DVNNNIMELLIMAYACKTSSASSIV 473
SV +N E V I + + G ++YIIQ TG + D+N +MELL++ + S+A S+
Sbjct: 74 SVTQYSNGEVNVRINECVLGADVYIIQSTTGNEIIDINTALMELLLLIRKMRLSNAKSVT 133
Query: 474 GVIPYLPYSKQ 506
+ P+ Y++Q
Sbjct: 134 VIAPFFGYARQ 144
>UniRef50_A7HHV4 Cluster: Ribose-phosphate pyrophosphokinase; n=3;
Cystobacterineae|Rep: Ribose-phosphate pyrophosphokinase
- Anaeromyxobacter sp. Fw109-5
Length = 311
Score = 48.0 bits (109), Expect = 3e-04
Identities = 18/59 (30%), Positives = 38/59 (64%)
Frame = +3
Query: 330 ETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVGVIPYLPYSKQ 506
E V + + +RG +Y++Q + + +++EL+ +A AC+ + A S+ V+PYL +++Q
Sbjct: 38 ELRVVVKEPVRGAEVYLVQPLSPPADAHLLELVFLADACRRAGARSVTAVVPYLAWARQ 96
Score = 44.8 bits (101), Expect = 0.003
Identities = 27/78 (34%), Positives = 44/78 (56%), Gaps = 6/78 (7%)
Frame = +2
Query: 545 LAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIPESIPDYRNSVIV--- 715
LA + + ++++D+H +GFF P+D+L A+P L I S+P R++V+V
Sbjct: 110 LAADLISARADRVVSVDVHGPAAEGFFSVPLDHLTAAPALAAAIARSVP--RDAVVVGPD 167
Query: 716 ---ARNPALQRKLLHMPS 760
AR AL +LL +PS
Sbjct: 168 LGAARRAALFGRLLGLPS 185
>UniRef50_UPI00015BACA3 Cluster: ribose-phosphate pyrophosphokinase;
n=1; Ignicoccus hospitalis KIN4/I|Rep: ribose-phosphate
pyrophosphokinase - Ignicoccus hospitalis KIN4/I
Length = 298
Score = 46.0 bits (104), Expect = 0.001
Identities = 18/59 (30%), Positives = 36/59 (61%)
Frame = +3
Query: 330 ETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVGVIPYLPYSKQ 506
E+ V I + G+++ ++ TG D N+ ++E+L+ K A S+ ++PY+PY++Q
Sbjct: 37 ESYVRIPIPVSGEDVLVVHTGFPDQNDRVIEVLLTIDTLKDLGAESVTLLMPYMPYARQ 95
>UniRef50_Q5GTH9 Cluster: Phosphoribosylpyrophosphate synthetase;
n=6; Wolbachia|Rep: Phosphoribosylpyrophosphate
synthetase - Wolbachia sp. subsp. Brugia malayi (strain
TRS)
Length = 308
Score = 46.0 bits (104), Expect = 0.001
Identities = 21/55 (38%), Positives = 34/55 (61%)
Frame = +3
Query: 342 EIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVGVIPYLPYSKQ 506
E+ ++ + +YIIQ+ + VN+++MELL + A K S I +IPY YS+Q
Sbjct: 40 EVESNLCSQEVYIIQSISPPVNDHLMELLFIIDAVKRSGTKRITTIIPYYGYSRQ 94
Score = 41.1 bits (92), Expect = 0.033
Identities = 16/37 (43%), Positives = 26/37 (70%)
Frame = +2
Query: 536 SKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNL 646
+KL+A ++ +G S + +DLH +I+GFFD P+ NL
Sbjct: 109 AKLVANLIQTAGASSVAVIDLHSSQIEGFFDVPLTNL 145
>UniRef50_A2X0F3 Cluster: Ribose-phosphate pyrophosphokinase; n=2;
Oryza sativa|Rep: Ribose-phosphate pyrophosphokinase -
Oryza sativa subsp. indica (Rice)
Length = 330
Score = 44.0 bits (99), Expect = 0.005
Identities = 17/46 (36%), Positives = 30/46 (65%)
Frame = +2
Query: 509 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNL 646
K + R I +KL+A M+ ++G + ++ DLH + G+FD PVD++
Sbjct: 150 KSQGRESIAAKLVANMITEAGANRVLVCDLHSSQAMGYFDIPVDHV 195
>UniRef50_Q4DSS9 Cluster: Ribose-phosphate pyrophosphokinase,
putative; n=3; Trypanosoma|Rep: Ribose-phosphate
pyrophosphokinase, putative - Trypanosoma cruzi
Length = 705
Score = 42.7 bits (96), Expect = 0.011
Identities = 17/63 (26%), Positives = 39/63 (61%), Gaps = 4/63 (6%)
Frame = +2
Query: 542 LLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRAS----PFLLQYIPESIPDYRNSV 709
++A+++ K G H+IT+D+ ++++G F P++N+ A F+ +++ D+RN
Sbjct: 377 VVAELLEKMGCQHVITVDMSSEQVEGMFSVPLENISARYEFVRFIAKHLTNEGHDFRNIT 436
Query: 710 IVA 718
+V+
Sbjct: 437 VVS 439
Score = 39.1 bits (87), Expect = 0.13
Identities = 20/65 (30%), Positives = 37/65 (56%), Gaps = 6/65 (9%)
Frame = +3
Query: 324 NRETIVEIADSIRGKNIYIIQTGTK------DVNNNIMELLIMAYACKTSSASSIVGVIP 485
N E V ++ ++RG +++++Q+ + + MEL +M + + SSA+ I VIP
Sbjct: 305 NGEINVSLSRTLRGDDVFVLQSLVRCDHLGLSHSGTFMELALMLHTARLSSAARITAVIP 364
Query: 486 YLPYS 500
YL Y+
Sbjct: 365 YLAYA 369
>UniRef50_Q97Z86 Cluster: Ribose-phosphate pyrophosphokinase; n=5;
Sulfolobaceae|Rep: Ribose-phosphate pyrophosphokinase -
Sulfolobus solfataricus
Length = 291
Score = 42.7 bits (96), Expect = 0.011
Identities = 16/59 (27%), Positives = 34/59 (57%)
Frame = +3
Query: 330 ETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVGVIPYLPYSKQ 506
E+ + + SIR + + ++QT + +++EL ++A + A + ++PYL YS+Q
Sbjct: 36 ESYIRVPSSIRDEEVLLVQTTDYPQDKHLIELFLIAETIRDLGAKKLTAIVPYLAYSRQ 94
>UniRef50_Q8KKS6 Cluster: Ribose-phosphate pyrophosphokinase
protein; n=1; Rhizobium etli CFN 42|Rep:
Ribose-phosphate pyrophosphokinase protein - Rhizobium
etli (strain CFN 42 / ATCC 51251)
Length = 313
Score = 41.1 bits (92), Expect = 0.033
Identities = 19/61 (31%), Positives = 32/61 (52%)
Frame = +3
Query: 321 TNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVGVIPYLPYS 500
+N + V D G N+ ++QT V++ + EL + A + +I V+PYLPYS
Sbjct: 49 SNGQMAVTPRDGGLGGNVVVVQTFPDSVHDRLFELFLALGAVRARGPRTITAVLPYLPYS 108
Query: 501 K 503
+
Sbjct: 109 R 109
Score = 37.9 bits (84), Expect = 0.30
Identities = 17/57 (29%), Positives = 34/57 (59%)
Frame = +2
Query: 524 GCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIPESIPD 694
G + ++LA ++ G+ +IT +LH ++ F CPV NL+ +P L++++ + D
Sbjct: 118 GPVPVRILAGIIETLGIDRLITFELHVPQLCAAFACPVVNLQFAPALVRHLGSAAVD 174
>UniRef50_Q660Y0 Cluster: Phosphoribosyl pyrophosphate synthetase;
n=3; Borrelia burgdorferi group|Rep: Phosphoribosyl
pyrophosphate synthetase - Borrelia garinii
Length = 406
Score = 40.7 bits (91), Expect = 0.043
Identities = 22/74 (29%), Positives = 41/74 (55%), Gaps = 1/74 (1%)
Frame = +2
Query: 509 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFF-DCPVDNLRASPFLLQYIPES 685
K R C+ + L+ + + + G+ HI+T+D+H K I+ F +NL S + + + +
Sbjct: 166 KKHSRECLTASLIGRFLEELGIRHILTLDIHSKAIENVFRKVYFENLNVSYEIFKSLGDL 225
Query: 686 IPDYRNSVIVARNP 727
I D R+S +V +P
Sbjct: 226 I-DIRDSNLVIVSP 238
Score = 37.1 bits (82), Expect = 0.53
Identities = 27/77 (35%), Positives = 40/77 (51%), Gaps = 14/77 (18%)
Frame = +3
Query: 324 NRETIVEIADSIRGKNIYIIQ--TGTKDV------------NNNIMELLIMAYACKTSSA 461
N E EI +IR K+I+I+Q T +V N++IM L+ AC + A
Sbjct: 90 NGEFKTEILKTIRNKDIFIVQDVANTYEVEINSSEKIIMTVNDHIMNLMTTIDACMQAKA 149
Query: 462 SSIVGVIPYLPYSKQ*K 512
+S+ +IP PYS+Q K
Sbjct: 150 NSVSVIIPSYPYSRQDK 166
>UniRef50_O62580 Cluster: Phosphoribosyl pyrophosphate synthetase;
n=2; Giardia intestinalis|Rep: Phosphoribosyl
pyrophosphate synthetase - Giardia lamblia (Giardia
intestinalis)
Length = 370
Score = 40.7 bits (91), Expect = 0.043
Identities = 20/60 (33%), Positives = 36/60 (60%), Gaps = 1/60 (1%)
Frame = +3
Query: 330 ETIVEIADSIRGKNIYIIQTGTKD-VNNNIMELLIMAYACKTSSASSIVGVIPYLPYSKQ 506
E ++ +IRG +++I+ N+N+MELL+ A K +SA+ + +IPY Y++Q
Sbjct: 47 EINLQYESNIRGCDLFIVGAICPPRCNDNLMELLLAIDAAKRASAAHVTAIIPYFGYARQ 106
Score = 39.5 bits (88), Expect = 0.100
Identities = 21/73 (28%), Positives = 38/73 (52%), Gaps = 3/73 (4%)
Frame = +2
Query: 509 KMRKRGCIVSKLLAQMMCKSGLSHIITMDLHQKEIQGFF--DCPVDNLRASPFLLQYIPE 682
K R I +KL+ ++ SG+ ++ D+H +IQGFF P D++ +Q I +
Sbjct: 109 KAASRTPISAKLVTDLLIASGVDRVVVQDIHAAQIQGFFPSSIPFDHIDGYLVFIQAIID 168
Query: 683 SI-PDYRNSVIVA 718
D +N ++V+
Sbjct: 169 RFEEDIKNLIVVS 181
>UniRef50_Q9EWS0 Cluster: Putative ribose-phosphate
pyrophosphokinase; n=9; Actinomycetales|Rep: Putative
ribose-phosphate pyrophosphokinase - Streptomyces
coelicolor
Length = 317
Score = 40.7 bits (91), Expect = 0.043
Identities = 15/38 (39%), Positives = 25/38 (65%)
Frame = +2
Query: 539 KLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRA 652
+L+A ++ +G S ++ M LH ++ GFF PVD+L A
Sbjct: 110 RLVADLLVAAGASRVLAMTLHSPQVHGFFSVPVDHLHA 147
Score = 36.3 bits (80), Expect = 0.93
Identities = 16/58 (27%), Positives = 35/58 (60%)
Frame = +3
Query: 339 VEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVGVIPYLPYSKQ*K 512
V++ + R ++++++Q V +++ELL+M A + +SA I V+P+ Y++ K
Sbjct: 42 VQLMANCRERDVFLVQPLVTPVQEHLVELLMMCDAARGASAGRITVVMPHYSYARSDK 99
>UniRef50_A2XQT7 Cluster: Putative uncharacterized protein; n=1;
Oryza sativa (indica cultivar-group)|Rep: Putative
uncharacterized protein - Oryza sativa subsp. indica
(Rice)
Length = 165
Score = 39.9 bits (89), Expect = 0.075
Identities = 19/41 (46%), Positives = 29/41 (70%)
Frame = +3
Query: 357 IRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVGV 479
+RG +++++Q T VN N+M+LLIM AC +SA+SI V
Sbjct: 85 LRGYDVFLVQP-TCPVNENLMDLLIMTDACMRASANSITAV 124
>UniRef50_Q4QIB8 Cluster: Ribose-phosphate pyrophosphokinase,
putative; n=3; Leishmania|Rep: Ribose-phosphate
pyrophosphokinase, putative - Leishmania major
Length = 836
Score = 39.5 bits (88), Expect = 0.100
Identities = 22/81 (27%), Positives = 46/81 (56%), Gaps = 6/81 (7%)
Frame = +3
Query: 276 QPPRVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQT----GTKDVNNN--IMELLIMA 437
Q PR C + N E V + +RG +++++Q+ +++++N +MEL ++
Sbjct: 357 QCPRFPGNSCGRF--ANGEVSVNLQAPVRGDDVFVVQSMVALESENLSNAGALMELALLV 414
Query: 438 YACKTSSASSIVGVIPYLPYS 500
++ + ++A+ I VIPYL Y+
Sbjct: 415 HSAQLAAAARITAVIPYLAYT 435
Score = 38.3 bits (85), Expect = 0.23
Identities = 15/54 (27%), Positives = 31/54 (57%)
Frame = +2
Query: 545 LAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIPESIPDYRNS 706
+A+M+ G H+IT+D+H +++G F P+++ A ++YI + N+
Sbjct: 444 VAEMIELVGCHHVITVDMHSDQVEGMFSIPIESASAMYEFVRYISNLLESEGNT 497
>UniRef50_A4BQ39 Cluster: Ribose-phosphate pyrophosphokinase; n=9;
Proteobacteria|Rep: Ribose-phosphate pyrophosphokinase -
Nitrococcus mobilis Nb-231
Length = 362
Score = 38.3 bits (85), Expect = 0.23
Identities = 16/56 (28%), Positives = 34/56 (60%), Gaps = 4/56 (7%)
Frame = +3
Query: 351 DSIRGKNIYII----QTGTKDVNNNIMELLIMAYACKTSSASSIVGVIPYLPYSKQ 506
+ +RG+++Y++ Q ++ VN+ ++ LL A + + A + VIPYL Y+++
Sbjct: 78 EGVRGRDVYVLHSLYQDASEGVNDKLVRLLFFLGALRDAHAGCLTAVIPYLAYARK 133
>UniRef50_A1HDW3 Cluster: Ribose-phosphate diphosphokinase; n=3;
Ralstonia|Rep: Ribose-phosphate diphosphokinase -
Ralstonia pickettii 12J
Length = 313
Score = 37.5 bits (83), Expect = 0.40
Identities = 21/76 (27%), Positives = 36/76 (47%)
Frame = +3
Query: 279 PPRVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSS 458
P R G +V H + E+ V + + G + I+ T + ++ LL +A A +
Sbjct: 30 PLRAELGHAAVTHFPDGESYVRLYTPVHGAEVAIVCT-LDHPDEKLLPLLWLAIAARQGG 88
Query: 459 ASSIVGVIPYLPYSKQ 506
A + + PYLPY +Q
Sbjct: 89 ARRVGLIAPYLPYMRQ 104
>UniRef50_Q8ZU24 Cluster: Ribose-phosphate pyrophosphokinase; n=4;
Pyrobaculum|Rep: Ribose-phosphate pyrophosphokinase -
Pyrobaculum aerophilum
Length = 284
Score = 37.5 bits (83), Expect = 0.40
Identities = 19/59 (32%), Positives = 37/59 (62%)
Frame = +3
Query: 330 ETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVGVIPYLPYSKQ 506
E +V + ++ RG+ + ++ VN+N+++L + A + AS I+ VIPY+PY++Q
Sbjct: 33 EVLVRLPEA-RGE-VAVVARLYPAVNDNLIKLFLTIDALNDAGASKIILVIPYMPYARQ 89
>UniRef50_O26877 Cluster: Ribose-phosphate pyrophosphokinase; n=3;
Methanobacteriaceae|Rep: Ribose-phosphate
pyrophosphokinase - Methanobacterium thermoautotrophicum
Length = 285
Score = 37.5 bits (83), Expect = 0.40
Identities = 15/49 (30%), Positives = 30/49 (61%)
Frame = +2
Query: 530 IVSKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYI 676
+ +K++A ++ +G I+T++LH+ + FF PV L A P + ++I
Sbjct: 102 VSAKIVAHLLEAAGADEIVTVNLHENCLSEFFRVPVRELSAMPLIAEHI 150
Score = 33.5 bits (73), Expect = 6.6
Identities = 16/59 (27%), Positives = 29/59 (49%)
Frame = +3
Query: 330 ETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVGVIPYLPYSKQ 506
E + + + + G+ + ++Q+ + N+MELL M K A + IPY Y +Q
Sbjct: 35 ERYIRVKEEVEGE-VTVVQSTGYPQDENLMELLFMIENLKDLGADYVRAAIPYFGYGRQ 92
>UniRef50_Q3YQZ8 Cluster: Ribose-phosphate pyrophospho kinase; n=1;
Ehrlichia canis str. Jake|Rep: Ribose-phosphate
pyrophospho kinase - Ehrlichia canis (strain Jake)
Length = 318
Score = 35.9 bits (79), Expect = 1.2
Identities = 18/61 (29%), Positives = 34/61 (55%)
Frame = +2
Query: 536 SKLLAQMMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIPESIPDYRNSVIV 715
+K++ + + +++II +DLH ++ GFFD + NL + ++ I D N VIV
Sbjct: 117 AKVIINTLETANINNIIFIDLHSNQLTGFFDTSITNLSSHAIFIEDIAGKY-DMDNLVIV 175
Query: 716 A 718
+
Sbjct: 176 S 176
>UniRef50_O83317 Cluster: Phosphoribosyl pyrophosphate synthetase;
n=2; Treponema|Rep: Phosphoribosyl pyrophosphate
synthetase - Treponema pallidum
Length = 421
Score = 35.5 bits (78), Expect = 1.6
Identities = 23/75 (30%), Positives = 42/75 (56%), Gaps = 5/75 (6%)
Frame = +2
Query: 530 IVSKLLAQMMCKSGLSHIITMDLHQKEIQ-GFFDCPVDNLRASPFLLQYIPE----SIPD 694
+ + LL + G+SHI+T+DLH +EI+ F ++NL AS +++ + + S PD
Sbjct: 178 LTAGLLGSVYEYLGVSHIVTLDLHSREIENAFHRTRLENLHASYQIIRELAKIENLSDPD 237
Query: 695 YRNSVIVARNPALQR 739
V+ + A++R
Sbjct: 238 IPFVVVAPDSGAVER 252
Score = 34.7 bits (76), Expect = 2.8
Identities = 26/83 (31%), Positives = 41/83 (49%), Gaps = 16/83 (19%)
Frame = +3
Query: 324 NRETIVEIADSIRGKNIYIIQ-----------TGTK----DVNNNIMELLIMAYACKTSS 458
N E +I + IRGK+++I Q G VN+++M L++ A + +
Sbjct: 94 NGELKTQINECIRGKDVFIFQDVENHQPVLVNNGKSKKIFSVNDHVMMLIVTIDAVRHAG 153
Query: 459 ASSIVGVIPYLPYSKQ-*KCGNE 524
A + V+P PYS+Q KCG E
Sbjct: 154 AGRVTLVLPTYPYSRQHKKCGRE 176
>UniRef50_A4WYL1 Cluster: Putative uncharacterized protein; n=1;
Rhodobacter sphaeroides ATCC 17025|Rep: Putative
uncharacterized protein - Rhodobacter sphaeroides ATCC
17025
Length = 347
Score = 35.1 bits (77), Expect = 2.1
Identities = 17/55 (30%), Positives = 33/55 (60%), Gaps = 4/55 (7%)
Frame = +3
Query: 354 SIRGKNIY---IIQTG-TKDVNNNIMELLIMAYACKTSSASSIVGVIPYLPYSKQ 506
S+RG + ++ G VN+ ++ LL+ A C+T+ A+ ++ V P+LPY ++
Sbjct: 69 SVRGHEVCLFSVLHAGEVGSVNDALVRLLLFAACCRTNGAARVLIVSPWLPYMRK 123
>UniRef50_Q8TUT6 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Methanopyrus kandleri|Rep: Ribose-phosphate
pyrophosphokinase - Methanopyrus kandleri
Length = 291
Score = 35.1 bits (77), Expect = 2.1
Identities = 13/59 (22%), Positives = 33/59 (55%)
Frame = +3
Query: 330 ETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVGVIPYLPYSKQ 506
E IV + + G + ++ + + + N+++ +I A + + A ++ ++PY+ YS+Q
Sbjct: 36 EQIVRVPPELDG-TVVVVHSMSPPQDENLVKAIITLDAARENGAEEVIAIVPYMAYSRQ 93
>UniRef50_Q9F9G7 Cluster: Cwp66; n=19; Clostridium difficile|Rep:
Cwp66 - Clostridium difficile
Length = 610
Score = 34.3 bits (75), Expect = 3.8
Identities = 23/66 (34%), Positives = 31/66 (46%)
Frame = +3
Query: 279 PPRVRKGGCSVYHKTNRETIVEIADSIRGKNIYIIQTGTKDVNNNIMELLIMAYACKTSS 458
P R G S +TN + I E KNIY+ + GTK+ N+ I L + A K SS
Sbjct: 225 PNATRIAGSS-RSETNAKIIEEFYKDTDIKNIYVTKDGTKNKNDLIDSLAVGVLAAKNSS 283
Query: 459 ASSIVG 476
+ G
Sbjct: 284 PIVLAG 289
>UniRef50_UPI0000EBE223 Cluster: PREDICTED: similar to
OTTHUMP00000016587; n=3; Laurasiatheria|Rep: PREDICTED:
similar to OTTHUMP00000016587 - Bos taurus
Length = 340
Score = 33.5 bits (73), Expect = 6.6
Identities = 24/87 (27%), Positives = 39/87 (44%)
Frame = +2
Query: 554 MMCKSGLSHIITMDLHQKEIQGFFDCPVDNLRASPFLLQYIPESIPDYRNSVIVARNPAL 733
M K G + + + LH E +C L L + PES+ Y + + R
Sbjct: 1 MYSKPGKTGVELLALHSPEKMQVLNCSTKLLLLEKMLKSHFPESLKVYGAVMNINRGNPF 60
Query: 734 QRKLLHMPSDETSYSCHTWRQKEAESD 814
Q++++ + S + T RQKEAE+D
Sbjct: 61 QKEVV-LDSWPDFKAIITRRQKEAETD 86
>UniRef50_O59586 Cluster: Ribose-phosphate pyrophosphokinase; n=4;
Thermococcaceae|Rep: Ribose-phosphate pyrophosphokinase
- Pyrococcus horikoshii
Length = 287
Score = 33.5 bits (73), Expect = 6.6
Identities = 13/48 (27%), Positives = 29/48 (60%)
Frame = +3
Query: 363 GKNIYIIQTGTKDVNNNIMELLIMAYACKTSSASSIVGVIPYLPYSKQ 506
G+ + ++Q+ + + +++E +I+ A K + + V+PYL YS+Q
Sbjct: 45 GEEVIVVQSTYRPQDEHLIETIIIGDALKEAGFEKLKLVVPYLAYSRQ 92
>UniRef50_Q5A0L1 Cluster: Putative uncharacterized protein; n=1;
Candida albicans|Rep: Putative uncharacterized protein -
Candida albicans (Yeast)
Length = 106
Score = 33.1 bits (72), Expect = 8.7
Identities = 17/43 (39%), Positives = 23/43 (53%), Gaps = 1/43 (2%)
Frame = +2
Query: 434 GLRL*DFLC-QFNCWCNSILTIQ*TMKMRKRGCIVSKLLAQMM 559
G + +F C F CWC SI + T+ RK C V LLA ++
Sbjct: 43 GYNIYNFSCIHFYCWCGSISISESTINNRKTCCSVFNLLACLL 85
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 828,380,499
Number of Sequences: 1657284
Number of extensions: 17276864
Number of successful extensions: 38099
Number of sequences better than 10.0: 97
Number of HSP's better than 10.0 without gapping: 36749
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 38083
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 71200899835
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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