Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= br--1227
(753 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Y12556-1|CAA73146.1| 270|Homo sapiens 5'-AMP-activated protein ... 86 1e-16
U87276-1|AAD00625.1| 270|Homo sapiens AMP-activated protein kin... 86 1e-16
U83994-1|AAD09237.1| 270|Homo sapiens AMP-activated protein kin... 86 1e-16
BC017671-1|AAH17671.1| 270|Homo sapiens protein kinase, AMP-act... 86 1e-16
BC001823-1|AAH01823.1| 270|Homo sapiens protein kinase, AMP-act... 86 1e-16
BC001056-1|AAH01056.1| 270|Homo sapiens protein kinase, AMP-act... 86 1e-16
BC001007-1|AAH01007.1| 270|Homo sapiens protein kinase, AMP-act... 86 1e-16
AJ224515-1|CAA12024.1| 270|Homo sapiens AMP-activated protein k... 86 1e-16
AF022116-1|AAC98897.1| 248|Homo sapiens 5'-AMP-activated protei... 86 1e-16
BC053610-1|AAH53610.1| 272|Homo sapiens protein kinase, AMP-act... 83 1e-15
AL356378-1|CAH72644.1| 272|Homo sapiens protein kinase, AMP-act... 83 1e-15
AJ224538-1|CAA12030.1| 272|Homo sapiens AMP-activated protein k... 83 1e-15
AF504543-1|AAM74153.1| 272|Homo sapiens AMPK beta-2 subunit pro... 83 1e-15
AC002563-1|AAB71326.1| 282|Homo sapiens WUGSC:H_127H14.2 protein. 82 2e-15
>Y12556-1|CAA73146.1| 270|Homo sapiens 5'-AMP-activated protein
kinase beta-1 protein.
Length = 270
Score = 85.8 bits (203), Expect = 1e-16
Identities = 41/87 (47%), Positives = 55/87 (63%), Gaps = 6/87 (6%)
Frame = +2
Query: 509 DLPEGEHQYKYFVDGEWRHDPTVKVIDNGMGSKNNLVTVKMSDFEVFQALAKDSE----- 673
DLPEGEHQYK+FVDG+W HDP+ ++ + +G+ NN++ VK +DFEVF AL DS+
Sbjct: 117 DLPEGEHQYKFFVDGQWTHDPSEPIVTSQLGTVNNIIQVKKTDFEVFDALMVDSQKCSDV 176
Query: 674 -GIHSSAQTEYSQEIPQSKPWEKVSGP 751
+ SS Y QE KP E+ P
Sbjct: 177 SELSSSPPGPYHQEPYVCKPEERFRAP 203
Score = 59.7 bits (138), Expect = 1e-08
Identities = 20/38 (52%), Positives = 31/38 (81%)
Frame = +3
Query: 396 PTVFKWEGGGKQVFISGTFTDWKTIPMVKSHGDFVTIM 509
PTVF+W GGGK+V++SG+F +W +P+ +SH +FV I+
Sbjct: 79 PTVFRWTGGGKEVYLSGSFNNWSKLPLTRSHNNFVAIL 116
>U87276-1|AAD00625.1| 270|Homo sapiens AMP-activated protein kinase
beta subunit protein.
Length = 270
Score = 85.8 bits (203), Expect = 1e-16
Identities = 41/87 (47%), Positives = 55/87 (63%), Gaps = 6/87 (6%)
Frame = +2
Query: 509 DLPEGEHQYKYFVDGEWRHDPTVKVIDNGMGSKNNLVTVKMSDFEVFQALAKDSE----- 673
DLPEGEHQYK+FVDG+W HDP+ ++ + +G+ NN++ VK +DFEVF AL DS+
Sbjct: 117 DLPEGEHQYKFFVDGQWTHDPSEPIVTSQLGTVNNIIQVKKTDFEVFDALMVDSQKCSDV 176
Query: 674 -GIHSSAQTEYSQEIPQSKPWEKVSGP 751
+ SS Y QE KP E+ P
Sbjct: 177 SELSSSPPGPYHQEPYVCKPEERFRAP 203
Score = 59.7 bits (138), Expect = 1e-08
Identities = 20/38 (52%), Positives = 31/38 (81%)
Frame = +3
Query: 396 PTVFKWEGGGKQVFISGTFTDWKTIPMVKSHGDFVTIM 509
PTVF+W GGGK+V++SG+F +W +P+ +SH +FV I+
Sbjct: 79 PTVFRWTGGGKEVYLSGSFNNWSKLPLTRSHNNFVAIL 116
>U83994-1|AAD09237.1| 270|Homo sapiens AMP-activated protein kinase
beta subunit protein.
Length = 270
Score = 85.8 bits (203), Expect = 1e-16
Identities = 41/87 (47%), Positives = 55/87 (63%), Gaps = 6/87 (6%)
Frame = +2
Query: 509 DLPEGEHQYKYFVDGEWRHDPTVKVIDNGMGSKNNLVTVKMSDFEVFQALAKDSE----- 673
DLPEGEHQYK+FVDG+W HDP+ ++ + +G+ NN++ VK +DFEVF AL DS+
Sbjct: 117 DLPEGEHQYKFFVDGQWTHDPSEPIVTSQLGTVNNIIQVKKTDFEVFDALMVDSQKCSDV 176
Query: 674 -GIHSSAQTEYSQEIPQSKPWEKVSGP 751
+ SS Y QE KP E+ P
Sbjct: 177 SELSSSPPGPYHQEPYVCKPEERFRAP 203
Score = 59.7 bits (138), Expect = 1e-08
Identities = 20/38 (52%), Positives = 31/38 (81%)
Frame = +3
Query: 396 PTVFKWEGGGKQVFISGTFTDWKTIPMVKSHGDFVTIM 509
PTVF+W GGGK+V++SG+F +W +P+ +SH +FV I+
Sbjct: 79 PTVFRWTGGGKEVYLSGSFNNWSKLPLTRSHNNFVAIL 116
>BC017671-1|AAH17671.1| 270|Homo sapiens protein kinase,
AMP-activated, beta 1 non-catalytic subunit protein.
Length = 270
Score = 85.8 bits (203), Expect = 1e-16
Identities = 41/87 (47%), Positives = 55/87 (63%), Gaps = 6/87 (6%)
Frame = +2
Query: 509 DLPEGEHQYKYFVDGEWRHDPTVKVIDNGMGSKNNLVTVKMSDFEVFQALAKDSE----- 673
DLPEGEHQYK+FVDG+W HDP+ ++ + +G+ NN++ VK +DFEVF AL DS+
Sbjct: 117 DLPEGEHQYKFFVDGQWTHDPSEPIVTSQLGTVNNIIQVKKTDFEVFDALMVDSQKCSDV 176
Query: 674 -GIHSSAQTEYSQEIPQSKPWEKVSGP 751
+ SS Y QE KP E+ P
Sbjct: 177 SELSSSPPGPYHQEPYVCKPEERFRAP 203
Score = 59.7 bits (138), Expect = 1e-08
Identities = 20/38 (52%), Positives = 31/38 (81%)
Frame = +3
Query: 396 PTVFKWEGGGKQVFISGTFTDWKTIPMVKSHGDFVTIM 509
PTVF+W GGGK+V++SG+F +W +P+ +SH +FV I+
Sbjct: 79 PTVFRWTGGGKEVYLSGSFNNWSKLPLTRSHNNFVAIL 116
>BC001823-1|AAH01823.1| 270|Homo sapiens protein kinase,
AMP-activated, beta 1 non-catalytic subunit protein.
Length = 270
Score = 85.8 bits (203), Expect = 1e-16
Identities = 41/87 (47%), Positives = 55/87 (63%), Gaps = 6/87 (6%)
Frame = +2
Query: 509 DLPEGEHQYKYFVDGEWRHDPTVKVIDNGMGSKNNLVTVKMSDFEVFQALAKDSE----- 673
DLPEGEHQYK+FVDG+W HDP+ ++ + +G+ NN++ VK +DFEVF AL DS+
Sbjct: 117 DLPEGEHQYKFFVDGQWTHDPSEPIVTSQLGTVNNIIQVKKTDFEVFDALMVDSQKCSDV 176
Query: 674 -GIHSSAQTEYSQEIPQSKPWEKVSGP 751
+ SS Y QE KP E+ P
Sbjct: 177 SELSSSPPGPYHQEPYVCKPEERFRAP 203
Score = 59.7 bits (138), Expect = 1e-08
Identities = 20/38 (52%), Positives = 31/38 (81%)
Frame = +3
Query: 396 PTVFKWEGGGKQVFISGTFTDWKTIPMVKSHGDFVTIM 509
PTVF+W GGGK+V++SG+F +W +P+ +SH +FV I+
Sbjct: 79 PTVFRWTGGGKEVYLSGSFNNWSKLPLTRSHNNFVAIL 116
>BC001056-1|AAH01056.1| 270|Homo sapiens protein kinase,
AMP-activated, beta 1 non-catalytic subunit protein.
Length = 270
Score = 85.8 bits (203), Expect = 1e-16
Identities = 41/87 (47%), Positives = 55/87 (63%), Gaps = 6/87 (6%)
Frame = +2
Query: 509 DLPEGEHQYKYFVDGEWRHDPTVKVIDNGMGSKNNLVTVKMSDFEVFQALAKDSE----- 673
DLPEGEHQYK+FVDG+W HDP+ ++ + +G+ NN++ VK +DFEVF AL DS+
Sbjct: 117 DLPEGEHQYKFFVDGQWTHDPSEPIVTSQLGTVNNIIQVKKTDFEVFDALMVDSQKCSDV 176
Query: 674 -GIHSSAQTEYSQEIPQSKPWEKVSGP 751
+ SS Y QE KP E+ P
Sbjct: 177 SELSSSPPGPYHQEPYVCKPEERFRAP 203
Score = 59.7 bits (138), Expect = 1e-08
Identities = 20/38 (52%), Positives = 31/38 (81%)
Frame = +3
Query: 396 PTVFKWEGGGKQVFISGTFTDWKTIPMVKSHGDFVTIM 509
PTVF+W GGGK+V++SG+F +W +P+ +SH +FV I+
Sbjct: 79 PTVFRWTGGGKEVYLSGSFNNWSKLPLTRSHNNFVAIL 116
>BC001007-1|AAH01007.1| 270|Homo sapiens protein kinase,
AMP-activated, beta 1 non-catalytic subunit protein.
Length = 270
Score = 85.8 bits (203), Expect = 1e-16
Identities = 41/87 (47%), Positives = 55/87 (63%), Gaps = 6/87 (6%)
Frame = +2
Query: 509 DLPEGEHQYKYFVDGEWRHDPTVKVIDNGMGSKNNLVTVKMSDFEVFQALAKDSE----- 673
DLPEGEHQYK+FVDG+W HDP+ ++ + +G+ NN++ VK +DFEVF AL DS+
Sbjct: 117 DLPEGEHQYKFFVDGQWTHDPSEPIVTSQLGTVNNIIQVKKTDFEVFDALMVDSQKCSDV 176
Query: 674 -GIHSSAQTEYSQEIPQSKPWEKVSGP 751
+ SS Y QE KP E+ P
Sbjct: 177 SELSSSPPGPYHQEPYVCKPEERFRAP 203
Score = 59.7 bits (138), Expect = 1e-08
Identities = 20/38 (52%), Positives = 31/38 (81%)
Frame = +3
Query: 396 PTVFKWEGGGKQVFISGTFTDWKTIPMVKSHGDFVTIM 509
PTVF+W GGGK+V++SG+F +W +P+ +SH +FV I+
Sbjct: 79 PTVFRWTGGGKEVYLSGSFNNWSKLPLTRSHNNFVAIL 116
>AJ224515-1|CAA12024.1| 270|Homo sapiens AMP-activated protein
kinase, beta 1 subunit protein.
Length = 270
Score = 85.8 bits (203), Expect = 1e-16
Identities = 41/87 (47%), Positives = 55/87 (63%), Gaps = 6/87 (6%)
Frame = +2
Query: 509 DLPEGEHQYKYFVDGEWRHDPTVKVIDNGMGSKNNLVTVKMSDFEVFQALAKDSE----- 673
DLPEGEHQYK+FVDG+W HDP+ ++ + +G+ NN++ VK +DFEVF AL DS+
Sbjct: 117 DLPEGEHQYKFFVDGQWTHDPSEPIVTSQLGTVNNIIQVKKTDFEVFDALMVDSQKCSDV 176
Query: 674 -GIHSSAQTEYSQEIPQSKPWEKVSGP 751
+ SS Y QE KP E+ P
Sbjct: 177 SELSSSPPGPYHQEPYVCKPEERFRAP 203
Score = 59.7 bits (138), Expect = 1e-08
Identities = 20/38 (52%), Positives = 31/38 (81%)
Frame = +3
Query: 396 PTVFKWEGGGKQVFISGTFTDWKTIPMVKSHGDFVTIM 509
PTVF+W GGGK+V++SG+F +W +P+ +SH +FV I+
Sbjct: 79 PTVFRWTGGGKEVYLSGSFNNWSKLPLTRSHNNFVAIL 116
>AF022116-1|AAC98897.1| 248|Homo sapiens 5'-AMP-activated protein
kinase beta-1 protein.
Length = 248
Score = 85.8 bits (203), Expect = 1e-16
Identities = 41/87 (47%), Positives = 55/87 (63%), Gaps = 6/87 (6%)
Frame = +2
Query: 509 DLPEGEHQYKYFVDGEWRHDPTVKVIDNGMGSKNNLVTVKMSDFEVFQALAKDSE----- 673
DLPEGEHQYK+FVDG+W HDP+ ++ + +G+ NN++ VK +DFEVF AL DS+
Sbjct: 117 DLPEGEHQYKFFVDGQWTHDPSEPIVTSQLGTVNNIIQVKKTDFEVFDALMVDSQKCSDV 176
Query: 674 -GIHSSAQTEYSQEIPQSKPWEKVSGP 751
+ SS Y QE KP E+ P
Sbjct: 177 SELSSSPPGPYHQEPYVCKPEERFRAP 203
Score = 59.7 bits (138), Expect = 1e-08
Identities = 20/38 (52%), Positives = 31/38 (81%)
Frame = +3
Query: 396 PTVFKWEGGGKQVFISGTFTDWKTIPMVKSHGDFVTIM 509
PTVF+W GGGK+V++SG+F +W +P+ +SH +FV I+
Sbjct: 79 PTVFRWTGGGKEVYLSGSFNNWSKLPLTRSHNNFVAIL 116
>BC053610-1|AAH53610.1| 272|Homo sapiens protein kinase,
AMP-activated, beta 2 non-catalytic subunit protein.
Length = 272
Score = 82.6 bits (195), Expect = 1e-15
Identities = 42/89 (47%), Positives = 54/89 (60%), Gaps = 8/89 (8%)
Frame = +2
Query: 509 DLPEGEHQYKYFVDGEWRHDPTVKVIDNGMGSKNNLVTVKMSDFEVFQALAKDS------ 670
DLPEGEHQYK+FVDG+W HDP+ V+ + +G+ NNL+ VK SDFEVF AL DS
Sbjct: 117 DLPEGEHQYKFFVDGQWVHDPSEPVVTSQLGTINNLIHVKKSDFEVFDALKLDSMESSET 176
Query: 671 --EGIHSSAQTEYSQEIPQSKPWEKVSGP 751
+ SS Y QE+ + E+ P
Sbjct: 177 SCRDLSSSPPGPYGQEMYAFRSEERFKSP 205
Score = 59.7 bits (138), Expect = 1e-08
Identities = 24/39 (61%), Positives = 31/39 (79%), Gaps = 1/39 (2%)
Frame = +3
Query: 396 PTVFKWEGGGKQVFISGTFTDWKT-IPMVKSHGDFVTIM 509
PTV +W GGK+VFISG+F +W T IP++KSH DFV I+
Sbjct: 78 PTVIRWSEGGKEVFISGSFNNWSTKIPLIKSHNDFVAIL 116
>AL356378-1|CAH72644.1| 272|Homo sapiens protein kinase,
AMP-activated, beta 2 non-catalytic subunit protein.
Length = 272
Score = 82.6 bits (195), Expect = 1e-15
Identities = 42/89 (47%), Positives = 54/89 (60%), Gaps = 8/89 (8%)
Frame = +2
Query: 509 DLPEGEHQYKYFVDGEWRHDPTVKVIDNGMGSKNNLVTVKMSDFEVFQALAKDS------ 670
DLPEGEHQYK+FVDG+W HDP+ V+ + +G+ NNL+ VK SDFEVF AL DS
Sbjct: 117 DLPEGEHQYKFFVDGQWVHDPSEPVVTSQLGTINNLIHVKKSDFEVFDALKLDSMESSET 176
Query: 671 --EGIHSSAQTEYSQEIPQSKPWEKVSGP 751
+ SS Y QE+ + E+ P
Sbjct: 177 SCRDLSSSPPGPYGQEMYAFRSEERFKSP 205
Score = 59.7 bits (138), Expect = 1e-08
Identities = 24/39 (61%), Positives = 31/39 (79%), Gaps = 1/39 (2%)
Frame = +3
Query: 396 PTVFKWEGGGKQVFISGTFTDWKT-IPMVKSHGDFVTIM 509
PTV +W GGK+VFISG+F +W T IP++KSH DFV I+
Sbjct: 78 PTVIRWSEGGKEVFISGSFNNWSTKIPLIKSHNDFVAIL 116
>AJ224538-1|CAA12030.1| 272|Homo sapiens AMP-activated protein
kinase beta 2 subunit protein.
Length = 272
Score = 82.6 bits (195), Expect = 1e-15
Identities = 42/89 (47%), Positives = 54/89 (60%), Gaps = 8/89 (8%)
Frame = +2
Query: 509 DLPEGEHQYKYFVDGEWRHDPTVKVIDNGMGSKNNLVTVKMSDFEVFQALAKDS------ 670
DLPEGEHQYK+FVDG+W HDP+ V+ + +G+ NNL+ VK SDFEVF AL DS
Sbjct: 117 DLPEGEHQYKFFVDGQWVHDPSEPVVTSQLGTINNLIHVKKSDFEVFDALKLDSMESSET 176
Query: 671 --EGIHSSAQTEYSQEIPQSKPWEKVSGP 751
+ SS Y QE+ + E+ P
Sbjct: 177 SCRDLSSSPPGPYGQEMYAFRSEERFKSP 205
Score = 59.7 bits (138), Expect = 1e-08
Identities = 24/39 (61%), Positives = 31/39 (79%), Gaps = 1/39 (2%)
Frame = +3
Query: 396 PTVFKWEGGGKQVFISGTFTDWKT-IPMVKSHGDFVTIM 509
PTV +W GGK+VFISG+F +W T IP++KSH DFV I+
Sbjct: 78 PTVIRWSEGGKEVFISGSFNNWSTKIPLIKSHNDFVAIL 116
>AF504543-1|AAM74153.1| 272|Homo sapiens AMPK beta-2 subunit
protein.
Length = 272
Score = 82.6 bits (195), Expect = 1e-15
Identities = 42/89 (47%), Positives = 54/89 (60%), Gaps = 8/89 (8%)
Frame = +2
Query: 509 DLPEGEHQYKYFVDGEWRHDPTVKVIDNGMGSKNNLVTVKMSDFEVFQALAKDS------ 670
DLPEGEHQYK+FVDG+W HDP+ V+ + +G+ NNL+ VK SDFEVF AL DS
Sbjct: 117 DLPEGEHQYKFFVDGQWVHDPSEPVVTSQLGTINNLIHVKKSDFEVFDALKLDSMESSET 176
Query: 671 --EGIHSSAQTEYSQEIPQSKPWEKVSGP 751
+ SS Y QE+ + E+ P
Sbjct: 177 SCRDLSSSPPGPYGQEMYAFRSEERFKSP 205
Score = 59.7 bits (138), Expect = 1e-08
Identities = 24/39 (61%), Positives = 31/39 (79%), Gaps = 1/39 (2%)
Frame = +3
Query: 396 PTVFKWEGGGKQVFISGTFTDWKT-IPMVKSHGDFVTIM 509
PTV +W GGK+VFISG+F +W T IP++KSH DFV I+
Sbjct: 78 PTVIRWSEGGKEVFISGSFNNWSTKIPLIKSHNDFVAIL 116
>AC002563-1|AAB71326.1| 282|Homo sapiens WUGSC:H_127H14.2 protein.
Length = 282
Score = 82.2 bits (194), Expect = 2e-15
Identities = 32/55 (58%), Positives = 44/55 (80%)
Frame = +2
Query: 509 DLPEGEHQYKYFVDGEWRHDPTVKVIDNGMGSKNNLVTVKMSDFEVFQALAKDSE 673
DLPEGEHQYK+FVDG+W HDP+ ++ + +G+ NN++ VK +DFEVF AL DS+
Sbjct: 117 DLPEGEHQYKFFVDGQWTHDPSEPIVTSQLGTVNNIIQVKKTDFEVFDALMVDSQ 171
Score = 59.7 bits (138), Expect = 1e-08
Identities = 20/38 (52%), Positives = 31/38 (81%)
Frame = +3
Query: 396 PTVFKWEGGGKQVFISGTFTDWKTIPMVKSHGDFVTIM 509
PTVF+W GGGK+V++SG+F +W +P+ +SH +FV I+
Sbjct: 79 PTVFRWTGGGKEVYLSGSFNNWSKLPLTRSHNNFVAIL 116
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 115,772,520
Number of Sequences: 237096
Number of extensions: 2675749
Number of successful extensions: 5142
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 4958
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5138
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 9071127468
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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