Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= br--1132
(607 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P26267 Cluster: Pyruvate dehydrogenase E1 component sub... 140 3e-32
UniRef50_Q6NX32 Cluster: Pyruvate dehydrogenase (Lipoamide) alph... 116 4e-25
UniRef50_P08559 Cluster: Pyruvate dehydrogenase E1 component sub... 112 5e-24
UniRef50_Q1EGI2 Cluster: Pyruvate dehydrogenase E1 alpha subunit... 107 2e-22
UniRef50_Q8H1Y0 Cluster: Pyruvate dehydrogenase E1 component sub... 107 2e-22
UniRef50_Q9W4H4 Cluster: CG7024-PA; n=2; Sophophora|Rep: CG7024-... 100 5e-20
UniRef50_P16387 Cluster: Pyruvate dehydrogenase E1 component sub... 97 2e-19
UniRef50_A2QWB4 Cluster: Catalytic activity: Pyruvate + Lipoamid... 93 4e-18
UniRef50_Q4QDQ1 Cluster: Pyruvate dehydrogenase E1 component alp... 92 1e-17
UniRef50_O96865 Cluster: Pyruvate dehydrogenase E1 alpha subunit... 92 1e-17
UniRef50_Q9R9N5 Cluster: Pyruvate dehydrogenase E1 component sub... 89 1e-16
UniRef50_Q4WHM5 Cluster: Pyruvate dehydrogenase E1 component alp... 88 1e-16
UniRef50_Q5FNM5 Cluster: Pyruvate dehydrogenase E1 component alp... 88 2e-16
UniRef50_A7CXZ4 Cluster: Pyruvate dehydrogenase; n=1; Opitutacea... 81 2e-14
UniRef50_Q23KL2 Cluster: Pyruvate dehydrogenase E1 component; n=... 80 3e-14
UniRef50_Q42066 Cluster: Pyruvate dehydrogenase E1 componen; n=5... 76 6e-13
UniRef50_O66112 Cluster: Pyruvate dehydrogenase E1 component sub... 76 6e-13
UniRef50_Q8TA29 Cluster: Putative pyruvate dehydrogenase; n=1; H... 75 1e-12
UniRef50_A4VXG8 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 73 5e-12
UniRef50_Q1AZ54 Cluster: Pyruvate dehydrogenase; n=1; Rubrobacte... 70 4e-11
UniRef50_A5UU15 Cluster: Pyruvate dehydrogenase; n=3; Chloroflex... 69 1e-10
UniRef50_A3VIE7 Cluster: Tpp-dependent acetoin dehydrogenase e1 ... 66 5e-10
UniRef50_A6Q3I6 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 66 8e-10
UniRef50_A5UVY9 Cluster: Pyruvate dehydrogenase; n=2; Roseiflexu... 64 2e-09
UniRef50_A0LTQ9 Cluster: Pyruvate dehydrogenase; n=1; Acidotherm... 64 2e-09
UniRef50_Q3J9C5 Cluster: Dehydrogenase, E1 component; n=3; Prote... 63 6e-09
UniRef50_Q1NYU1 Cluster: Pyruvate dehydrogenase E1 component alp... 62 7e-09
UniRef50_Q4T3C0 Cluster: Chromosome undetermined SCAF10102, whol... 62 1e-08
UniRef50_Q98FT3 Cluster: Acetoin dehydrogenase (TPP-dependent) a... 62 1e-08
UniRef50_Q18CB6 Cluster: Acetoin:2,6-dichlorophenolindophenol ox... 61 2e-08
UniRef50_Q1XDM0 Cluster: Pyruvate dehydrogenase E1 component sub... 60 4e-08
UniRef50_Q4QC52 Cluster: 2-oxoisovalerate dehydrogenase alpha su... 59 7e-08
UniRef50_Q1IQR3 Cluster: Dehydrogenase, E1 component; n=1; Acido... 59 9e-08
UniRef50_Q9KG99 Cluster: Pyruvate dehydrogenase E1 (Lipoamide) a... 58 2e-07
UniRef50_A6DTS3 Cluster: Dehydrogenase complex, E1 component, al... 57 3e-07
UniRef50_Q0RVK8 Cluster: Probable pyruvate dehydrogenase; n=1; R... 57 4e-07
UniRef50_A4XHV5 Cluster: Transketolase, central region; n=3; Bac... 56 7e-07
UniRef50_A0LSF3 Cluster: Pyruvate dehydrogenase; n=5; Bacteria|R... 56 7e-07
UniRef50_Q8AB00 Cluster: 2-oxoisovalerate dehydrogenase beta sub... 56 9e-07
UniRef50_Q9RPS5 Cluster: TPP-dependent branched-chain alpha-keto... 56 9e-07
UniRef50_Q2S150 Cluster: Pyruvate dehydrogenase E1 component, al... 55 1e-06
UniRef50_A5V4J0 Cluster: Pyruvate dehydrogenase; n=2; Sphingomon... 55 1e-06
UniRef50_Q74AD3 Cluster: Dehydrogenase complex, E1 component, al... 55 2e-06
UniRef50_Q1ARM0 Cluster: Pyruvate dehydrogenase; n=3; Bacteria|R... 55 2e-06
UniRef50_Q49108 Cluster: Pyruvate dehydrogenase EI alpha subunit... 54 3e-06
UniRef50_Q4DB65 Cluster: 2-oxoisovalerate dehydrogenase alpha su... 54 3e-06
UniRef50_Q9LPL5 Cluster: Branched-chain alpha keto-acid dehydrog... 54 3e-06
UniRef50_Q1KSF1 Cluster: Apicoplast pyruvate dehydrogenase E1 al... 54 3e-06
UniRef50_Q6MAE2 Cluster: Putative pyruvate dehydrogenase (Lipoam... 53 5e-06
UniRef50_Q5QUK4 Cluster: Alpha keto acid dehydrogenase complex, ... 53 5e-06
UniRef50_A0LLM4 Cluster: Pyruvate dehydrogenase; n=1; Syntrophob... 53 5e-06
UniRef50_Q97YF6 Cluster: Pyruvate dehydrogenase, alpha subunit (... 53 5e-06
UniRef50_Q72GU1 Cluster: 2-oxoisovalerate dehydrogenase subunit ... 53 5e-06
UniRef50_Q1ATM5 Cluster: Pyruvate dehydrogenase; n=1; Rubrobacte... 53 6e-06
UniRef50_Q9RYC1 Cluster: 2-oxo acid dehydrogenase, E1 component,... 52 8e-06
UniRef50_A7HBV0 Cluster: 3-methyl-2-oxobutanoate dehydrogenase; ... 52 8e-06
UniRef50_Q0W151 Cluster: Pyruvate dehydrogenase complex E1, tran... 52 8e-06
UniRef50_Q6YPX5 Cluster: Thiamine pyrophosphate-dependent dehydr... 52 1e-05
UniRef50_A6GG24 Cluster: Pyruvate dehydrogenase (Lipoamide), alp... 52 1e-05
UniRef50_Q12FH4 Cluster: Pyruvate dehydrogenase; n=37; Bacteria|... 51 2e-05
UniRef50_A6W004 Cluster: Transketolase domain protein; n=6; Prot... 51 2e-05
UniRef50_A4AFX0 Cluster: Acetoin dehydrogenase (TPP-dependent) a... 51 2e-05
UniRef50_Q835M4 Cluster: Pyruvate dehydrogenase complex E1 compo... 50 3e-05
UniRef50_Q8CX87 Cluster: Pyruvate dehydrogenase E1 (Lipoamide) a... 50 4e-05
UniRef50_Q67ME6 Cluster: Branched-chain alpha-keto acid dehydrog... 50 4e-05
UniRef50_Q2JA37 Cluster: Pyruvate dehydrogenase; n=11; Actinomyc... 50 4e-05
UniRef50_Q020J5 Cluster: Dehydrogenase, E1 component; n=1; Solib... 50 4e-05
UniRef50_Q9VHB8 Cluster: CG8199-PA; n=2; Eukaryota|Rep: CG8199-P... 50 6e-05
UniRef50_Q3E8Q6 Cluster: Uncharacterized protein At5g34780.1; n=... 49 7e-05
UniRef50_P37940 Cluster: 2-oxoisovalerate dehydrogenase subunit ... 49 7e-05
UniRef50_P47516 Cluster: Pyruvate dehydrogenase E1 component sub... 49 1e-04
UniRef50_Q749T8 Cluster: Pyruvate dehydrogenase complex E1 compo... 48 1e-04
UniRef50_Q4A1S8 Cluster: Putative uncharacterized protein; n=4; ... 48 2e-04
UniRef50_Q6A611 Cluster: Pyruvate dehydrogenase E1 component, al... 47 3e-04
UniRef50_Q4MTG0 Cluster: Pyruvate dehydrogenase E1 component sub... 47 3e-04
UniRef50_Q295J7 Cluster: GA20891-PA; n=7; Coelomata|Rep: GA20891... 47 4e-04
UniRef50_A6CP23 Cluster: Pyruvate dehydrogenase E1 (Lipoamide) a... 46 5e-04
UniRef50_Q3DZ88 Cluster: Dehydrogenase, E1 component; n=1; Chlor... 46 7e-04
UniRef50_A0LFE6 Cluster: Pyruvate dehydrogenase; n=1; Syntrophob... 46 7e-04
UniRef50_P35485 Cluster: Pyruvate dehydrogenase E1 component sub... 46 7e-04
UniRef50_P12694 Cluster: 2-oxoisovalerate dehydrogenase subunit ... 46 7e-04
UniRef50_Q9Z8N4 Cluster: Pyruvate Dehydrogenase Alpha; n=8; Chla... 46 0.001
UniRef50_A3CMZ3 Cluster: Pyruvate dehydrogenase, TPP-dependent E... 46 0.001
UniRef50_Q8YDW3 Cluster: 2-OXOISOVALERATE DEHYDROGENASE BETA SUB... 45 0.001
UniRef50_Q5KUY4 Cluster: Pyruvate dehydrogenase E1 (Lipoamide) a... 45 0.001
UniRef50_Q02C52 Cluster: Pyruvate dehydrogenase; n=1; Solibacter... 45 0.001
UniRef50_Q8SQM8 Cluster: PYRUVATE DEHYDROGENASE E1 COMPONENT ALP... 45 0.001
UniRef50_Q67SE7 Cluster: Pyruvate dehydrogenase E1 alpha subunit... 45 0.002
UniRef50_A5IXN2 Cluster: Pyruvate dehydrogenase E1 component, al... 45 0.002
UniRef50_Q97CK0 Cluster: 2-oxoisovalerate dehydrogenase alpha su... 45 0.002
UniRef50_A7K3C9 Cluster: Dehydrogenase E1 component superfamily;... 44 0.002
UniRef50_P21873 Cluster: Pyruvate dehydrogenase E1 component sub... 44 0.002
UniRef50_Q7NLM8 Cluster: Gll1094 protein; n=1; Gloeobacter viola... 44 0.003
UniRef50_Q3DYK5 Cluster: Dehydrogenase, E1 component; n=3; Bacte... 44 0.003
UniRef50_A4F1Y5 Cluster: Branched-chain alpha-keto acid decarbox... 44 0.003
UniRef50_A0UXT3 Cluster: Pyruvate dehydrogenase; n=1; Clostridiu... 44 0.003
UniRef50_Q4P2J0 Cluster: Putative uncharacterized protein; n=1; ... 44 0.003
UniRef50_Q8ZUR8 Cluster: Pyruvate dehydrogenase E1 alpha subunit... 44 0.003
UniRef50_Q2J998 Cluster: Pyruvate dehydrogenase; n=1; Frankia sp... 44 0.004
UniRef50_Q3WCG3 Cluster: Pyruvate dehydrogenase; n=4; Actinomyce... 43 0.005
UniRef50_Q2ITF8 Cluster: Acetoin dehydrogenase (TPP-dependent) a... 43 0.005
UniRef50_A7BPK6 Cluster: Pyruvate dehydrogenase; n=1; Beggiatoa ... 43 0.005
UniRef50_Q5VGY4 Cluster: Pyruvate dehydrogenase alpha subunit; n... 43 0.005
UniRef50_Q53610 Cluster: Branched-chain alpha-keto acid dehydrog... 43 0.006
UniRef50_Q319T4 Cluster: Pyruvate dehydrogenase; n=1; Prochloroc... 43 0.006
UniRef50_Q5SJR9 Cluster: Pyruvate dehydrogenase (Lipoamide) (EC ... 42 0.009
UniRef50_Q00TN9 Cluster: Pyruvate dehydrogenase E1 component bet... 42 0.009
UniRef50_A3SJ75 Cluster: 2-oxoisovalerate dehydrogenase beta sub... 42 0.011
UniRef50_A1UJ85 Cluster: Pyruvate dehydrogenase; n=16; Mycobacte... 42 0.011
UniRef50_Q3W421 Cluster: Pyruvate dehydrogenase; n=1; Frankia sp... 42 0.015
UniRef50_A3TUC4 Cluster: TPP-dependent acetoin dehydrogenase com... 41 0.020
UniRef50_A0M1U4 Cluster: 2-oxoisovalerate dehydrogenase E1 compo... 41 0.020
UniRef50_A0K283 Cluster: Pyruvate dehydrogenase; n=4; Actinobact... 41 0.026
UniRef50_A6WG12 Cluster: Pyruvate dehydrogenase; n=3; Actinomyce... 40 0.035
UniRef50_Q8EVQ2 Cluster: Pyruvate dehydrogenase E1 component sub... 40 0.046
UniRef50_Q9YBC0 Cluster: Pyruvate dehydrogenase E1 component, al... 40 0.046
UniRef50_Q8YDG0 Cluster: 2-OXOISOVALERATE DEHYDROGENASE BETA SUB... 40 0.060
UniRef50_Q83FF2 Cluster: Pyruvate dehydrogenase E1 component alp... 40 0.060
UniRef50_Q5KGR5 Cluster: Branched-chain alpha-keto acid dehydrog... 40 0.060
UniRef50_A3RZM3 Cluster: Pyruvate dehydrogenase E1 component alp... 39 0.080
UniRef50_Q95VS6 Cluster: Pyruvate dehydrogenase E1 alpha subunit... 39 0.080
UniRef50_UPI00005103B4 Cluster: COG1071: Pyruvate/2-oxoglutarate... 39 0.11
UniRef50_Q4L1A7 Cluster: Pyruvate dehydrogenase E1 component alp... 39 0.11
UniRef50_A0JY23 Cluster: Pyruvate dehydrogenase; n=2; Arthrobact... 39 0.11
UniRef50_Q8U4T5 Cluster: 2-oxo acid dehydrogenase subunit E1; n=... 39 0.11
UniRef50_A4SAP2 Cluster: Predicted protein; n=2; Ostreococcus|Re... 38 0.14
UniRef50_Q9HNV6 Cluster: Pyruvate dehydrogenase alpha subunit; n... 38 0.14
UniRef50_Q1IY28 Cluster: Pyruvate dehydrogenase; n=1; Deinococcu... 38 0.24
UniRef50_A6UDY5 Cluster: Dehydrogenase E1 component; n=2; Alphap... 38 0.24
UniRef50_Q6L1L8 Cluster: Pyruvate dehydrogenase E1 component alp... 38 0.24
UniRef50_A0HHH5 Cluster: Dehydrogenase, E1 component; n=2; Bacte... 37 0.43
UniRef50_Q4N1L6 Cluster: Branched-chain alpha keto-acid dehydrog... 37 0.43
UniRef50_Q2H9L8 Cluster: Putative uncharacterized protein; n=2; ... 37 0.43
UniRef50_Q93N50 Cluster: Pyruvate dehydrogenase alpha subunit; n... 36 0.56
UniRef50_Q8PQ82 Cluster: Pyruvate dehydrogenase E1 alpha subunit... 36 0.56
UniRef50_Q8D6Q7 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 36 0.56
UniRef50_A5V557 Cluster: Pyruvate dehydrogenase; n=1; Sphingomon... 36 0.56
UniRef50_A0JUQ5 Cluster: Pyruvate dehydrogenase; n=4; Actinobact... 36 0.56
UniRef50_P09060 Cluster: 2-oxoisovalerate dehydrogenase subunit ... 36 0.56
UniRef50_Q28MR4 Cluster: Dehydrogenase E1 component; n=8; Bacter... 36 0.74
UniRef50_Q0RLC2 Cluster: Pyruvate dehydrogenase E1 component, al... 36 0.74
UniRef50_A7PGG3 Cluster: Chromosome chr17 scaffold_16, whole gen... 36 0.74
UniRef50_A0DAM1 Cluster: Chromosome undetermined scaffold_43, wh... 36 0.74
UniRef50_Q9Z9E8 Cluster: (Pyruvate) Oxoisovalerate Dehydrogenase... 35 1.7
UniRef50_Q7QY55 Cluster: GLP_572_50389_48461; n=2; Giardia intes... 35 1.7
UniRef50_Q1KSF2 Cluster: Mitochondrial branched-chain alpha-keto... 35 1.7
UniRef50_Q0MX87 Cluster: Acetoin dehydrogenase alpha-subunit; n=... 34 2.3
UniRef50_Q9FNY4 Cluster: DNA polymerase lambda; n=31; Spermatoph... 34 2.3
UniRef50_A5KBH9 Cluster: Putative uncharacterized protein; n=1; ... 34 2.3
UniRef50_UPI00004993C7 Cluster: hypothetical protein 3.t00030; n... 34 3.0
UniRef50_Q83DQ6 Cluster: Dehydrogenase, E1 component, alpha subu... 34 3.0
UniRef50_Q1LFS5 Cluster: Dehydrogenase, E1 component; n=22; Prot... 34 3.0
UniRef50_A3PXW7 Cluster: Transketolase domain protein; n=4; Myco... 34 3.0
UniRef50_Q7Q6F7 Cluster: ENSANGP00000004512; n=2; Diptera|Rep: E... 34 3.0
UniRef50_Q3SE24 Cluster: KdG6; n=9; Paramecium tetraurelia|Rep: ... 34 3.0
UniRef50_A7RZV6 Cluster: Predicted protein; n=6; Eumetazoa|Rep: ... 34 3.0
UniRef50_UPI0000F2B7FC Cluster: PREDICTED: similar to F-box prot... 33 4.0
UniRef50_Q5LVW0 Cluster: Dehydrogenase/transketolase family prot... 33 4.0
UniRef50_UPI0000E4A126 Cluster: PREDICTED: similar to Im:7141452... 33 5.2
UniRef50_Q2S3D2 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 33 5.2
UniRef50_Q83X26 Cluster: Probable pyruvate dehydrogenase alpha-s... 33 6.9
UniRef50_Q023C4 Cluster: Pyruvate dehydrogenase; n=1; Solibacter... 33 6.9
UniRef50_A6Q7R1 Cluster: Putative uncharacterized protein; n=1; ... 33 6.9
UniRef50_A6LT96 Cluster: Transposase IS3/IS911 family protein; n... 33 6.9
UniRef50_Q8ILU2 Cluster: Putative uncharacterized protein; n=2; ... 33 6.9
UniRef50_Q5CW69 Cluster: PP2C like protein phosphatase; n=2; Cry... 33 6.9
UniRef50_UPI00015A6B18 Cluster: UPI00015A6B18 related cluster; n... 32 9.2
UniRef50_Q4AAN6 Cluster: Putative uncharacterized protein; n=5; ... 32 9.2
UniRef50_Q2SHW5 Cluster: Putative uncharacterized protein; n=1; ... 32 9.2
UniRef50_A1GCL6 Cluster: Transketolase-like; n=2; Salinispora|Re... 32 9.2
UniRef50_Q8I2L0 Cluster: Putative uncharacterized protein PFI148... 32 9.2
UniRef50_Q6UEA5 Cluster: Zinc metallopeptidase 6; n=5; Ancylosto... 32 9.2
UniRef50_Q23RJ8 Cluster: Putative uncharacterized protein; n=1; ... 32 9.2
UniRef50_Q2HHP7 Cluster: Putative uncharacterized protein; n=1; ... 32 9.2
UniRef50_Q0CEB2 Cluster: Predicted protein; n=2; Trichocomaceae|... 32 9.2
UniRef50_A6S0G6 Cluster: Predicted protein; n=1; Botryotinia fuc... 32 9.2
UniRef50_Q8U3N7 Cluster: Putative uncharacterized protein PF0420... 32 9.2
UniRef50_Q13029 Cluster: PR domain zinc finger protein 2; n=16; ... 32 9.2
UniRef50_Q8YJE4 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 32 9.2
UniRef50_A5E032 Cluster: mRNA cap guanine-N7 methyltransferase (... 32 9.2
>UniRef50_P26267 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha type I, mitochondrial precursor; n=10;
cellular organisms|Rep: Pyruvate dehydrogenase E1
component subunit alpha type I, mitochondrial precursor
- Ascaris suum (Pig roundworm) (Ascaris lumbricoides)
Length = 396
Score = 140 bits (338), Expect = 3e-32
Identities = 62/89 (69%), Positives = 78/89 (87%)
Frame = +1
Query: 4 EYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELV 183
E+CNAGKGPL++EM TYRYSGHSMSDPGTSYRTR+EVQEVR+TRDPIT FK+KI+ LV
Sbjct: 267 EWCNAGKGPLMIEMATYRYSGHSMSDPGTSYRTREEVQEVRKTRDPITGFKDKIVTAGLV 326
Query: 184 TPDQLKDIDAKVRKEVDEATKQSKRNQKS 270
T D++K+ID +VRKE+D A KQ+ +++S
Sbjct: 327 TEDEIKEIDKQVRKEIDAAVKQAHTDKES 355
>UniRef50_Q6NX32 Cluster: Pyruvate dehydrogenase (Lipoamide) alpha
1; n=3; Tetrapoda|Rep: Pyruvate dehydrogenase
(Lipoamide) alpha 1 - Xenopus tropicalis (Western clawed
frog) (Silurana tropicalis)
Length = 369
Score = 116 bits (279), Expect = 4e-25
Identities = 47/81 (58%), Positives = 68/81 (83%)
Frame = +1
Query: 4 EYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELV 183
++C +GKGP++ME++TYRY GHSMSDPG SYRTR+E+QEVR DPIT K+++LN+ L
Sbjct: 250 DHCRSGKGPILMELQTYRYHGHSMSDPGVSYRTREEIQEVRSKSDPITLLKDRMLNNNLS 309
Query: 184 TPDQLKDIDAKVRKEVDEATK 246
+ ++LK+ID +VRKE++EA +
Sbjct: 310 SVEELKEIDVEVRKEIEEAAQ 330
>UniRef50_P08559 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha, somatic form, mitochondrial precursor;
n=110; cellular organisms|Rep: Pyruvate dehydrogenase E1
component subunit alpha, somatic form, mitochondrial
precursor - Homo sapiens (Human)
Length = 390
Score = 112 bits (270), Expect = 5e-24
Identities = 45/80 (56%), Positives = 65/80 (81%)
Frame = +1
Query: 7 YCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVT 186
YC +GKGP++ME++TYRY GHSMSDPG SYRTR+E+QEVR DPI K++++N L +
Sbjct: 272 YCRSGKGPILMELQTYRYHGHSMSDPGVSYRTREEIQEVRSKSDPIMLLKDRMVNSNLAS 331
Query: 187 PDQLKDIDAKVRKEVDEATK 246
++LK+ID +VRKE+++A +
Sbjct: 332 VEELKEIDVEVRKEIEDAAQ 351
>UniRef50_Q1EGI2 Cluster: Pyruvate dehydrogenase E1 alpha subunit;
n=6; Spirotrichea|Rep: Pyruvate dehydrogenase E1 alpha
subunit - Euplotes sp. BB-2004
Length = 389
Score = 107 bits (258), Expect = 2e-22
Identities = 46/86 (53%), Positives = 62/86 (72%)
Frame = +1
Query: 4 EYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELV 183
+YC GKGPL E++TYRY GHSMSDPG +YRTR+EV E R+T+DPI K+ IL H++
Sbjct: 267 KYCTDGKGPLFFELQTYRYHGHSMSDPGITYRTREEVNEYRKTQDPILLVKKWILEHDIA 326
Query: 184 TPDQLKDIDAKVRKEVDEATKQSKRN 261
T LK+ID ++R +DE +Q K +
Sbjct: 327 TEKYLKEIDKEIRARIDEEVEQIKND 352
>UniRef50_Q8H1Y0 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha-2, mitochondrial precursor; n=33; cellular
organisms|Rep: Pyruvate dehydrogenase E1 component
subunit alpha-2, mitochondrial precursor - Arabidopsis
thaliana (Mouse-ear cress)
Length = 393
Score = 107 bits (257), Expect = 2e-22
Identities = 43/79 (54%), Positives = 63/79 (79%)
Frame = +1
Query: 25 GPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQLKD 204
GP+++EM+TYRY GHSMSDPG++YRTRDE+ VRQ RDPI ++ +L H++ T +LKD
Sbjct: 281 GPIILEMDTYRYHGHSMSDPGSTYRTRDEISGVRQVRDPIERVRKLLLTHDIATEKELKD 340
Query: 205 IDAKVRKEVDEATKQSKRN 261
++ ++RKEVD+A Q+K +
Sbjct: 341 MEKEIRKEVDDAVAQAKES 359
>UniRef50_Q9W4H4 Cluster: CG7024-PA; n=2; Sophophora|Rep: CG7024-PA
- Drosophila melanogaster (Fruit fly)
Length = 479
Score = 99.5 bits (237), Expect = 5e-20
Identities = 44/81 (54%), Positives = 61/81 (75%)
Frame = +1
Query: 25 GPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQLKD 204
GP+V+EM TYRY GHSMSDPGTSYR+R+EVQ R+ RDPITSF+ +I+ L ++LK
Sbjct: 279 GPIVLEMSTYRYVGHSMSDPGTSYRSREEVQSTREKRDPITSFRSQIIALCLADEEELKA 338
Query: 205 IDAKVRKEVDEATKQSKRNQK 267
+D K RK+VD K++ +++
Sbjct: 339 LDDKTRKQVDSICKKATTDRE 359
>UniRef50_P16387 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha, mitochondrial precursor; n=34;
Dikarya|Rep: Pyruvate dehydrogenase E1 component subunit
alpha, mitochondrial precursor - Saccharomyces
cerevisiae (Baker's yeast)
Length = 420
Score = 97.5 bits (232), Expect = 2e-19
Identities = 42/78 (53%), Positives = 55/78 (70%)
Frame = +1
Query: 4 EYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELV 183
++C +GKGPLV+E ETYRY GHSMSDPGT+YRTRDE+Q +R DPI K +++ +
Sbjct: 291 DWCLSGKGPLVLEYETYRYGGHSMSDPGTTYRTRDEIQHMRSKNDPIAGLKMHLIDLGIA 350
Query: 184 TPDQLKDIDAKVRKEVDE 237
T ++K D RK VDE
Sbjct: 351 TEAEVKAYDKSARKYVDE 368
>UniRef50_A2QWB4 Cluster: Catalytic activity: Pyruvate + Lipoamide
<=> S-Acetyldihydrolipoamide + CO2; n=3; Ascomycota|Rep:
Catalytic activity: Pyruvate + Lipoamide <=>
S-Acetyldihydrolipoamide + CO2 - Aspergillus niger
Length = 403
Score = 93.5 bits (222), Expect = 4e-18
Identities = 40/93 (43%), Positives = 66/93 (70%)
Frame = +1
Query: 4 EYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELV 183
+Y G GPL+ E +TYRY+GHS+SDPGT+YR+RDEVQ R DPIT+++EK++ ++
Sbjct: 283 DYVLGGNGPLLYEFQTYRYAGHSVSDPGTAYRSRDEVQAER-ANDPITTYREKMIEWGVL 341
Query: 184 TPDQLKDIDAKVRKEVDEATKQSKRNQKSVLKS 282
+ D +K +D ++R +VD +++++ + L S
Sbjct: 342 SEDDVKTMDKEIRSKVDREAQEAEKMAEPPLNS 374
>UniRef50_Q4QDQ1 Cluster: Pyruvate dehydrogenase E1 component alpha
subunit, putative; n=5; Euglenozoa|Rep: Pyruvate
dehydrogenase E1 component alpha subunit, putative -
Leishmania major
Length = 378
Score = 91.9 bits (218), Expect = 1e-17
Identities = 37/91 (40%), Positives = 62/91 (68%)
Frame = +1
Query: 4 EYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELV 183
+YC +GKGP+VME++ YRY GHSMSDP YRT+ ++Q V+Q RD I +E + ++
Sbjct: 262 DYCMSGKGPIVMELDCYRYMGHSMSDPDNQYRTKSDIQHVKQERDCIRKMREFMATEGIM 321
Query: 184 TPDQLKDIDAKVRKEVDEATKQSKRNQKSVL 276
T D++ ++ V+KEVD+ +++++ + L
Sbjct: 322 TEDEMSKMEKDVKKEVDQDLQKAQKQPMTKL 352
>UniRef50_O96865 Cluster: Pyruvate dehydrogenase E1 alpha subunit;
n=2; Trypanosoma cruzi|Rep: Pyruvate dehydrogenase E1
alpha subunit - Trypanosoma cruzi
Length = 378
Score = 91.9 bits (218), Expect = 1e-17
Identities = 36/87 (41%), Positives = 64/87 (73%)
Frame = +1
Query: 4 EYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELV 183
E+C +GKGP+V+E ++YRY GHSMSDP + YR + ++Q+VR+TRD I K+ +L ++
Sbjct: 262 EWCLSGKGPIVLEFDSYRYVGHSMSDPDSQYRKKSDIQDVRKTRDCIHKMKDFMLEEGIM 321
Query: 184 TPDQLKDIDAKVRKEVDEATKQSKRNQ 264
T +++K ++ V+KEVD+ + +++ +
Sbjct: 322 TDEEMKKLEKDVKKEVDQQLQPAEKQK 348
>UniRef50_Q9R9N5 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha; n=62; Bacteria|Rep: Pyruvate
dehydrogenase E1 component subunit alpha - Rhizobium
meliloti (Sinorhizobium meliloti)
Length = 348
Score = 88.6 bits (210), Expect = 1e-16
Identities = 39/80 (48%), Positives = 56/80 (70%)
Frame = +1
Query: 1 IEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHEL 180
+E+C +GKGP+++EM TYRY GHSMSDP YR++DEVQ++R DPI K ++ +
Sbjct: 249 VEHCRSGKGPIILEMLTYRYRGHSMSDP-AKYRSKDEVQKMRSEHDPIEQVKARLTDKGW 307
Query: 181 VTPDQLKDIDAKVRKEVDEA 240
T D+LK ID +VR V ++
Sbjct: 308 ATEDELKQIDKEVRDIVADS 327
>UniRef50_Q4WHM5 Cluster: Pyruvate dehydrogenase E1 component alpha
subunit, putative; n=1; Aspergillus fumigatus|Rep:
Pyruvate dehydrogenase E1 component alpha subunit,
putative - Aspergillus fumigatus (Sartorya fumigata)
Length = 360
Score = 88.2 bits (209), Expect = 1e-16
Identities = 38/85 (44%), Positives = 60/85 (70%)
Frame = +1
Query: 4 EYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELV 183
E+ AG GPLV E TYRY+GHSMSDPG YRTR E++ R + DP+++F+ ++++ ++
Sbjct: 242 EFIRAGNGPLVYEYVTYRYAGHSMSDPGVGYRTRGELKAERAS-DPVSNFRAQLIDWGII 300
Query: 184 TPDQLKDIDAKVRKEVDEATKQSKR 258
T D+ K ID VRK+V+ ++++
Sbjct: 301 TEDEAKTIDKNVRKKVNHEVAEAEK 325
>UniRef50_Q5FNM5 Cluster: Pyruvate dehydrogenase E1 component alpha
subunit; n=4; Bacteria|Rep: Pyruvate dehydrogenase E1
component alpha subunit - Gluconobacter oxydans
(Gluconobacter suboxydans)
Length = 334
Score = 87.8 bits (208), Expect = 2e-16
Identities = 42/82 (51%), Positives = 57/82 (69%)
Frame = +1
Query: 1 IEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHEL 180
+EYC +GKGP ++EMETYRY GHSMSDP YR R EV+E+R+TRDPI + K ++L
Sbjct: 234 MEYCRSGKGPFLLEMETYRYRGHSMSDP-AKYRQRAEVEEMRRTRDPIETLKAEMLRSG- 291
Query: 181 VTPDQLKDIDAKVRKEVDEATK 246
+ KDI+ V+ V +AT+
Sbjct: 292 IEESVFKDIETDVKAIVADATE 313
>UniRef50_A7CXZ4 Cluster: Pyruvate dehydrogenase; n=1; Opitutaceae
bacterium TAV2|Rep: Pyruvate dehydrogenase - Opitutaceae
bacterium TAV2
Length = 365
Score = 81.4 bits (192), Expect = 2e-14
Identities = 33/71 (46%), Positives = 52/71 (73%)
Frame = +1
Query: 28 PLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQLKDI 207
P V+E++TYRY GHS++DP +YRTRDE++E R+T+DPI F++ +L +++T +++I
Sbjct: 257 PAVVEIDTYRYRGHSVADPDKTYRTRDEIEEYRKTKDPINLFQQTLLAEKVLTDALIEEI 316
Query: 208 DAKVRKEVDEA 240
D R E D A
Sbjct: 317 DTAARAEADHA 327
>UniRef50_Q23KL2 Cluster: Pyruvate dehydrogenase E1 component; n=5;
Intramacronucleata|Rep: Pyruvate dehydrogenase E1
component - Tetrahymena thermophila SB210
Length = 429
Score = 80.2 bits (189), Expect = 3e-14
Identities = 36/79 (45%), Positives = 54/79 (68%)
Frame = +1
Query: 25 GPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQLKD 204
GPL +E+ TYRY GHSMSD GT+YRT++E++E RQ +D I IL + T +QL+
Sbjct: 314 GPLFIELRTYRYHGHSMSDSGTTYRTQEEIKEFRQKKDCIQFIANTILQNNFATQEQLEA 373
Query: 205 IDAKVRKEVDEATKQSKRN 261
I + R+ VD+A +Q+ ++
Sbjct: 374 IQDETREIVDKAVEQALKD 392
>UniRef50_Q42066 Cluster: Pyruvate dehydrogenase E1 componen; n=5;
Eukaryota|Rep: Pyruvate dehydrogenase E1 componen -
Arabidopsis thaliana (Mouse-ear cress)
Length = 127
Score = 76.2 bits (179), Expect = 6e-13
Identities = 31/46 (67%), Positives = 38/46 (82%)
Frame = +1
Query: 22 KGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKE 159
KGP+++EM+TYRY GHSMS PG++YRTRDE+ VRQ RDPI KE
Sbjct: 77 KGPIILEMDTYRYHGHSMSXPGSTYRTRDEISXVRQERDPIERIKE 122
>UniRef50_O66112 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha; n=38; Proteobacteria|Rep: Pyruvate
dehydrogenase E1 component subunit alpha - Zymomonas
mobilis
Length = 354
Score = 76.2 bits (179), Expect = 6e-13
Identities = 39/100 (39%), Positives = 64/100 (64%)
Frame = +1
Query: 1 IEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHEL 180
+++ AGKGP+++EM+TYRY GHSMSDP YR+R+EV ++++ DP+ + K K L
Sbjct: 253 VDWVQAGKGPIILEMKTYRYRGHSMSDP-ARYRSREEVNDMKENHDPLDNLK-KDLFAAG 310
Query: 181 VTPDQLKDIDAKVRKEVDEATKQSKRNQKSVLKSXXPIYT 300
V +L +D +R++V EA + +K+ L + +YT
Sbjct: 311 VPEAELVKLDEDIRQQVKEAADFA---EKAPLPADEELYT 347
>UniRef50_Q8TA29 Cluster: Putative pyruvate dehydrogenase; n=1;
Heterodera glycines|Rep: Putative pyruvate dehydrogenase
- Heterodera glycines (Soybean cyst nematode worm)
Length = 132
Score = 74.9 bits (176), Expect = 1e-12
Identities = 34/49 (69%), Positives = 43/49 (87%)
Frame = +1
Query: 100 TRDEVQEVRQTRDPITSFKEKILNHELVTPDQLKDIDAKVRKEVDEATK 246
TRDE+QEVR++RDPITSFK++I+ LVT ++LKDID KVR+EVDEA K
Sbjct: 1 TRDEIQEVRKSRDPITSFKDRIVTAGLVTEEELKDIDKKVRQEVDEAVK 49
>UniRef50_A4VXG8 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex, dehydrogenase (E1) component, eukaryotic type,
alpha subunit; n=40; Streptococcus|Rep:
Pyruvate/2-oxoglutarate dehydrogenase complex,
dehydrogenase (E1) component, eukaryotic type, alpha
subunit - Streptococcus suis (strain 05ZYH33)
Length = 337
Score = 72.9 bits (171), Expect = 5e-12
Identities = 32/82 (39%), Positives = 58/82 (70%)
Frame = +1
Query: 1 IEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHEL 180
IEY AGKGP ++E+E+YR+ GHS +D G YRT++EV E + +DP+ +++ + +++
Sbjct: 238 IEYVRAGKGPAMVEVESYRWFGHSTADAGV-YRTKEEVNEWK-AKDPLKKYRKYLTENKI 295
Query: 181 VTPDQLKDIDAKVRKEVDEATK 246
T ++L I+A+V ++V+ + K
Sbjct: 296 ATDEELDAIEAQVAEQVEASVK 317
>UniRef50_Q1AZ54 Cluster: Pyruvate dehydrogenase; n=1; Rubrobacter
xylanophilus DSM 9941|Rep: Pyruvate dehydrogenase -
Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 325
Score = 70.1 bits (164), Expect = 4e-11
Identities = 33/84 (39%), Positives = 52/84 (61%)
Frame = +1
Query: 1 IEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHEL 180
+E G+GP ++E TYR+ GH DP T YR R+EV+ R+ RDPI ++ + L
Sbjct: 226 VERARRGEGPSLIEAMTYRFRGHYEGDPDT-YRDREEVERWRKERDPILLLANRLRSEGL 284
Query: 181 VTPDQLKDIDAKVRKEVDEATKQS 252
+ L+ I A+V++EVDEA +++
Sbjct: 285 ASEQDLEQIRARVQREVDEAAEEA 308
>UniRef50_A5UU15 Cluster: Pyruvate dehydrogenase; n=3; Chloroflexi
(class)|Rep: Pyruvate dehydrogenase - Roseiflexus sp.
RS-1
Length = 350
Score = 68.5 bits (160), Expect = 1e-10
Identities = 29/82 (35%), Positives = 52/82 (63%)
Frame = +1
Query: 1 IEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHEL 180
+E+ +GKGP+++E TYR+ GHS D YRT+++++ R+ DPI ++ +LN +
Sbjct: 239 VEHARSGKGPVLLEAMTYRFRGHSAQDT-QKYRTKEDIERHRR-NDPIVRYRTLLLNEGI 296
Query: 181 VTPDQLKDIDAKVRKEVDEATK 246
T Q++DID + +V+ A +
Sbjct: 297 ATEQQIRDIDRMIDDQVEAAVR 318
>UniRef50_A3VIE7 Cluster: Tpp-dependent acetoin dehydrogenase e1
alpha-subunit; n=2; Rhodobacterales|Rep: Tpp-dependent
acetoin dehydrogenase e1 alpha-subunit - Rhodobacterales
bacterium HTCC2654
Length = 335
Score = 66.5 bits (155), Expect = 5e-10
Identities = 26/78 (33%), Positives = 51/78 (65%), Gaps = 1/78 (1%)
Frame = +1
Query: 10 CNAGKGPLVMEMETYRYSGHSMSDPGTSY-RTRDEVQEVRQTRDPITSFKEKILNHELVT 186
C G+GP +E+ETYRY GH + D Y R++DE ++ R+ RDPI F+ +++ + +
Sbjct: 236 CRKGEGPFFVELETYRYHGHHVGDINREYYRSKDEEKDWRENRDPIIRFRAYLVDQGIAS 295
Query: 187 PDQLKDIDAKVRKEVDEA 240
++++ ++A++ K+ +A
Sbjct: 296 EEEIEAMNAEIEKDATDA 313
>UniRef50_A6Q3I6 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex, E1 component, alpha subunit; n=2; unclassified
Epsilonproteobacteria|Rep: Pyruvate/2-oxoglutarate
dehydrogenase complex, E1 component, alpha subunit -
Nitratiruptor sp. (strain SB155-2)
Length = 323
Score = 65.7 bits (153), Expect = 8e-10
Identities = 33/79 (41%), Positives = 48/79 (60%)
Frame = +1
Query: 4 EYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELV 183
EY G GP +E ETYRY GHSMSD G YR+ +E+ E+ ++RDPI K++ + +V
Sbjct: 218 EYLENGLGPYFIEAETYRYEGHSMSDNG-KYRSEEEM-EIFKSRDPIEKLKKEAIALGIV 275
Query: 184 TPDQLKDIDAKVRKEVDEA 240
+ D +V +E+ EA
Sbjct: 276 EESYFDETDKRVEQEIAEA 294
>UniRef50_A5UVY9 Cluster: Pyruvate dehydrogenase; n=2;
Roseiflexus|Rep: Pyruvate dehydrogenase - Roseiflexus
sp. RS-1
Length = 334
Score = 64.5 bits (150), Expect = 2e-09
Identities = 30/81 (37%), Positives = 50/81 (61%)
Frame = +1
Query: 1 IEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHEL 180
+E +G GP ++E +TYR+ H+ +D YR +EV+ R RDPI F+ ++ H +
Sbjct: 235 MERARSGGGPTLLECKTYRFRPHTSADDDRRYRKPEEVEAWR-ARDPIKRFEHYLVEHGI 293
Query: 181 VTPDQLKDIDAKVRKEVDEAT 243
+T D+++ + +VR EVD AT
Sbjct: 294 ITHDEIEAMRREVRAEVDAAT 314
>UniRef50_A0LTQ9 Cluster: Pyruvate dehydrogenase; n=1; Acidothermus
cellulolyticus 11B|Rep: Pyruvate dehydrogenase -
Acidothermus cellulolyticus (strain ATCC 43068 / 11B)
Length = 342
Score = 64.5 bits (150), Expect = 2e-09
Identities = 34/85 (40%), Positives = 51/85 (60%)
Frame = +1
Query: 1 IEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHEL 180
I C G GP+++E TYR GHS +DPGT YR ++EV E RDP+T ++E +L
Sbjct: 237 IAECRTGGGPVLIEALTYRQGGHSRADPGT-YRPKEEV-EAWLARDPVTCYREHLLASG- 293
Query: 181 VTPDQLKDIDAKVRKEVDEATKQSK 255
L +I+A+ EVD A ++++
Sbjct: 294 YPAGTLDEIEARATAEVDRAVEEAR 318
>UniRef50_Q3J9C5 Cluster: Dehydrogenase, E1 component; n=3;
Proteobacteria|Rep: Dehydrogenase, E1 component -
Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848)
Length = 339
Score = 62.9 bits (146), Expect = 6e-09
Identities = 31/78 (39%), Positives = 49/78 (62%)
Frame = +1
Query: 1 IEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHEL 180
I + +G GP +E TYRY GHSMSD G +YR+++EV E Q RDPI ++++
Sbjct: 224 IAHVRSGAGPYFLEFLTYRYRGHSMSDAG-AYRSKEEVAEWMQ-RDPIQILAKRLIEAGE 281
Query: 181 VTPDQLKDIDAKVRKEVD 234
+T ++ K ++ V+ E+D
Sbjct: 282 LTEEEFKAMEQAVQSEID 299
>UniRef50_Q1NYU1 Cluster: Pyruvate dehydrogenase E1 component alpha
subunit; n=1; Candidatus Sulcia muelleri str. Hc
(Homalodisca coagulata)|Rep: Pyruvate dehydrogenase E1
component alpha subunit - Candidatus Sulcia muelleri
str. Hc (Homalodisca coagulata)
Length = 167
Score = 62.5 bits (145), Expect = 7e-09
Identities = 31/76 (40%), Positives = 47/76 (61%)
Frame = +1
Query: 19 GKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQL 198
G GP +++ TYRY GHSM+D T YR++ EV E + RDPI K+ IL +++VT L
Sbjct: 64 GNGPTFLDILTYRYRGHSMTDAET-YRSKKEVNE-SKNRDPILLIKKFILKNKIVTEKVL 121
Query: 199 KDIDAKVRKEVDEATK 246
++ K+++E K
Sbjct: 122 NSFQDEINKKINECVK 137
>UniRef50_Q4T3C0 Cluster: Chromosome undetermined SCAF10102, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF10102,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 491
Score = 62.1 bits (144), Expect = 1e-08
Identities = 25/52 (48%), Positives = 39/52 (75%)
Frame = +1
Query: 91 SYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQLKDIDAKVRKEVDEATK 246
SYRTRDE+QEVR DPI+ K+++L + + + ++ K+ID +RKEV+EA +
Sbjct: 401 SYRTRDEIQEVRSKSDPISMLKDRMLGNNMASVEEFKEIDISIRKEVEEAAQ 452
>UniRef50_Q98FT3 Cluster: Acetoin dehydrogenase (TPP-dependent)
alpha chain; n=6; Bacteria|Rep: Acetoin dehydrogenase
(TPP-dependent) alpha chain - Rhizobium loti
(Mesorhizobium loti)
Length = 342
Score = 62.1 bits (144), Expect = 1e-08
Identities = 31/101 (30%), Positives = 58/101 (57%), Gaps = 1/101 (0%)
Frame = +1
Query: 1 IEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHEL 180
+E AG+GP ++E +TYR+ GHS SD YRT++E+++ RDPIT F+ ++
Sbjct: 240 VERARAGEGPTLIESKTYRHRGHSKSD-RNRYRTKEEIEDWMSNRDPITLFENELREFGF 298
Query: 181 VTPDQLKDIDAKVRKEVDEATKQSKRN-QKSVLKSXXPIYT 300
+ ++ I + V +E+ + + +K + V ++ +YT
Sbjct: 299 IDDKGIEAIRSAVSQEIADGIEFAKASPSPDVSETGNYVYT 339
>UniRef50_Q18CB6 Cluster: Acetoin:2,6-dichlorophenolindophenol
oxidoreductase alpha subunit; n=2; Clostridium
difficile|Rep: Acetoin:2,6-dichlorophenolindophenol
oxidoreductase alpha subunit - Clostridium difficile
(strain 630)
Length = 322
Score = 61.3 bits (142), Expect = 2e-08
Identities = 29/93 (31%), Positives = 54/93 (58%)
Frame = +1
Query: 4 EYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELV 183
E C G+GP+++E TYR+ GHS SD YRT++E+ E + +DPI K ++ + L
Sbjct: 224 EKCRRGEGPVLIESRTYRWLGHSKSDANV-YRTKEEI-ESWKAKDPIEFLKNYLIENNLS 281
Query: 184 TPDQLKDIDAKVRKEVDEATKQSKRNQKSVLKS 282
D+L I ++ +++A + ++ + ++S
Sbjct: 282 NEDELDKIQEFAKQSIEDAVEFAQNSPNPKIES 314
>UniRef50_Q1XDM0 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha; n=52; cellular organisms|Rep: Pyruvate
dehydrogenase E1 component subunit alpha - Porphyra
yezoensis
Length = 346
Score = 60.1 bits (139), Expect = 4e-08
Identities = 30/82 (36%), Positives = 49/82 (59%)
Frame = +1
Query: 1 IEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHEL 180
++ G GP ++E TYR+ GHS++DP R+R E +E RDPI K+ IL++E+
Sbjct: 246 VQRARQGDGPTLIEALTYRFRGHSLADP-DELRSRQE-KEAWVARDPIKKLKKYILDNEI 303
Query: 181 VTPDQLKDIDAKVRKEVDEATK 246
+L +I V+ E+++A K
Sbjct: 304 ANIGELNEIQNAVKTELEQAVK 325
>UniRef50_Q4QC52 Cluster: 2-oxoisovalerate dehydrogenase alpha
subunit, putative; n=3; Leishmania|Rep: 2-oxoisovalerate
dehydrogenase alpha subunit, putative - Leishmania major
Length = 479
Score = 59.3 bits (137), Expect = 7e-08
Identities = 29/77 (37%), Positives = 45/77 (58%), Gaps = 1/77 (1%)
Frame = +1
Query: 28 PLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQLKDI 207
P+++E TYR S HS SD T+YR+RDE++ +T PI F+ + TP+Q +++
Sbjct: 359 PVLVEALTYRLSHHSTSDDSTAYRSRDEIEHFAETFSPIERFEHFVTARGWWTPEQSREV 418
Query: 208 DAKVRKEV-DEATKQSK 255
+ R EV E +Q K
Sbjct: 419 VERTRSEVLSELRRQEK 435
>UniRef50_Q1IQR3 Cluster: Dehydrogenase, E1 component; n=1;
Acidobacteria bacterium Ellin345|Rep: Dehydrogenase, E1
component - Acidobacteria bacterium (strain Ellin345)
Length = 736
Score = 58.8 bits (136), Expect = 9e-08
Identities = 36/116 (31%), Positives = 55/116 (47%)
Frame = +1
Query: 1 IEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHEL 180
I+Y AGKGP + R HS+SD YR E ++ RDPIT F + ++ L
Sbjct: 267 IDYIRAGKGPAFVHGHVIRPYSHSLSDDEKLYRPEAERKD-EANRDPITKFYKWLVAESL 325
Query: 181 VTPDQLKDIDAKVRKEVDEATKQSKRNQKSVLKSXXPIYTTRTWNPSSVASTRLPR 348
T +LKD+ V EV +++ ++ L S + T +P+S A P+
Sbjct: 326 ATDKELKDLQTDVDTEVQDSSDRAVEAPIPALDSYSQHLYSSTLDPASAAFETRPQ 381
>UniRef50_Q9KG99 Cluster: Pyruvate dehydrogenase E1 (Lipoamide)
alpha subunit; n=1; Bacillus halodurans|Rep: Pyruvate
dehydrogenase E1 (Lipoamide) alpha subunit - Bacillus
halodurans
Length = 367
Score = 57.6 bits (133), Expect = 2e-07
Identities = 27/106 (25%), Positives = 56/106 (52%), Gaps = 2/106 (1%)
Frame = +1
Query: 1 IEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEV-RQTRDPITSFKEKILNHE 177
IE G+GP ++E T R+ H+ +D YR ++E++ ++ +DP+T K I
Sbjct: 244 IEQARKGRGPTLIEAVTTRFGSHTTADDAKKYRDQEEIERTWKEMQDPLTRLKAYIQAKG 303
Query: 178 LVTPDQLKDIDAKVRKEVDEATKQSKRNQK-SVLKSXXPIYTTRTW 312
++ ++ + AK+R+ +DE +++ K S+ + +Y + W
Sbjct: 304 WLSEEEEAQMKAKIRETIDEELSMAEQYPKPSISQMFEHVYENQPW 349
>UniRef50_A6DTS3 Cluster: Dehydrogenase complex, E1 component, alpha
subunit; n=1; Lentisphaera araneosa HTCC2155|Rep:
Dehydrogenase complex, E1 component, alpha subunit -
Lentisphaera araneosa HTCC2155
Length = 320
Score = 57.2 bits (132), Expect = 3e-07
Identities = 29/84 (34%), Positives = 49/84 (58%)
Frame = +1
Query: 10 CNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTP 189
C P ++ + TYRY GHS+SD G YRT+DEV+ ++ +DPI SF + + +
Sbjct: 225 CKKNSRPALVNVTTYRYQGHSVSDAGL-YRTKDEVKCWKE-KDPINSFYKSMEEQGWIDE 282
Query: 190 DQLKDIDAKVRKEVDEATKQSKRN 261
+ K +D +++ EV +A +K +
Sbjct: 283 EGYKALDKEMKAEVKDALDFAKES 306
>UniRef50_Q0RVK8 Cluster: Probable pyruvate dehydrogenase; n=1;
Rhodococcus sp. RHA1|Rep: Probable pyruvate
dehydrogenase - Rhodococcus sp. (strain RHA1)
Length = 344
Score = 56.8 bits (131), Expect = 4e-07
Identities = 29/83 (34%), Positives = 47/83 (56%)
Frame = +1
Query: 4 EYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELV 183
E G GP ++E +TYR +GH DP SYR + EV E + RDP+T ++ ++L + V
Sbjct: 243 ERARGGGGPTLVEAKTYRLNGHYEGDP-QSYRDKAEVAEWAE-RDPVTCYRARLLQQQNV 300
Query: 184 TPDQLKDIDAKVRKEVDEATKQS 252
T +QL + + E+ A ++
Sbjct: 301 TEEQLHTAEREAADEIRTAMTEA 323
>UniRef50_A4XHV5 Cluster: Transketolase, central region; n=3;
Bacteria|Rep: Transketolase, central region -
Caldicellulosiruptor saccharolyticus (strain ATCC 43494
/ DSM 8903)
Length = 823
Score = 56.0 bits (129), Expect = 7e-07
Identities = 24/68 (35%), Positives = 48/68 (70%)
Frame = +1
Query: 22 KGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQLK 201
+GP+++++ TYR +GHS SD T YRT++E+ E ++DP+ +FK++++ + T D++
Sbjct: 331 QGPVLLDVVTYRLTGHSPSDSST-YRTKEEL-EAWASQDPLVTFKDELIRVGVATEDKIN 388
Query: 202 DIDAKVRK 225
+I V++
Sbjct: 389 EIQQNVKE 396
>UniRef50_A0LSF3 Cluster: Pyruvate dehydrogenase; n=5; Bacteria|Rep:
Pyruvate dehydrogenase - Acidothermus cellulolyticus
(strain ATCC 43068 / 11B)
Length = 375
Score = 56.0 bits (129), Expect = 7e-07
Identities = 25/75 (33%), Positives = 48/75 (64%)
Frame = +1
Query: 22 KGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQLK 201
+ P ++E +YR GHS+ DP YR+++E Q + DP+T+F++++++ +++ D+
Sbjct: 265 RAPSILEAVSYRLRGHSVVDPAR-YRSKEEAQRLL-AHDPVTAFRQRLIDVGVLSADEAA 322
Query: 202 DIDAKVRKEVDEATK 246
IDA+V VD A +
Sbjct: 323 RIDAEVEAAVDAAVE 337
>UniRef50_Q8AB00 Cluster: 2-oxoisovalerate dehydrogenase beta
subunit; n=11; cellular organisms|Rep: 2-oxoisovalerate
dehydrogenase beta subunit - Bacteroides
thetaiotaomicron
Length = 678
Score = 55.6 bits (128), Expect = 9e-07
Identities = 24/83 (28%), Positives = 50/83 (60%)
Frame = +1
Query: 4 EYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELV 183
EY + + P++++ R HS SD T YR +E++ V++ DP+ F+ +L ++ +
Sbjct: 232 EYAISTRNPVIVQANCVRIGSHSNSDKHTLYRDENELEYVKEA-DPLMKFRRMLLRYKRL 290
Query: 184 TPDQLKDIDAKVRKEVDEATKQS 252
T ++L I+A+ +KE+ A +++
Sbjct: 291 TEEELLQIEAESKKELSAANRKA 313
>UniRef50_Q9RPS5 Cluster: TPP-dependent branched-chain alpha-keto
acid dehydrogenase, E1 alpha subunit; n=3;
Lactobacillales|Rep: TPP-dependent branched-chain
alpha-keto acid dehydrogenase, E1 alpha subunit -
Enterococcus faecalis (Streptococcus faecalis)
Length = 330
Score = 55.6 bits (128), Expect = 9e-07
Identities = 22/78 (28%), Positives = 51/78 (65%)
Frame = +1
Query: 22 KGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQLK 201
KGP ++E+ R + HS D + YR+++E++E+++ D + F++++L +T + +
Sbjct: 237 KGPKLIELMVSRLTSHSADDDQSVYRSKEEIEEMKK-NDAVKLFEKQLLEEGYLTDEDIA 295
Query: 202 DIDAKVRKEVDEATKQSK 255
ID ++R E+++AT +++
Sbjct: 296 KIDEEIRAEINQATDEAE 313
>UniRef50_Q2S150 Cluster: Pyruvate dehydrogenase E1 component, alpha
subunit; n=1; Salinibacter ruber DSM 13855|Rep: Pyruvate
dehydrogenase E1 component, alpha subunit - Salinibacter
ruber (strain DSM 13855)
Length = 470
Score = 55.2 bits (127), Expect = 1e-06
Identities = 27/71 (38%), Positives = 45/71 (63%)
Frame = +1
Query: 28 PLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQLKDI 207
P ++E+ TYRY GHS++DP YR E+ + RQ++D I ++ IL+ L T ++ I
Sbjct: 373 PSLLEVRTYRYQGHSITDP-AEYRGEGELDQ-RQSQDAINRLQDYILDRGLATEADMEAI 430
Query: 208 DAKVRKEVDEA 240
D +V++ V +A
Sbjct: 431 DEEVKERVKDA 441
>UniRef50_A5V4J0 Cluster: Pyruvate dehydrogenase; n=2; Sphingomonas
wittichii RW1|Rep: Pyruvate dehydrogenase - Sphingomonas
wittichii RW1
Length = 327
Score = 55.2 bits (127), Expect = 1e-06
Identities = 25/82 (30%), Positives = 47/82 (57%)
Frame = +1
Query: 1 IEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHEL 180
I+ AG+GP +E T+R++GH + + G Y + E+ QTRDP+ + ++++ +
Sbjct: 225 IDRARAGEGPTFIEATTFRFNGHLIGEAG-GYMDK-ELYAASQTRDPMPILRRRLVDQGI 282
Query: 181 VTPDQLKDIDAKVRKEVDEATK 246
+L +DA +R E+D A +
Sbjct: 283 AAAGELDALDASIRAEIDAAVQ 304
>UniRef50_Q74AD3 Cluster: Dehydrogenase complex, E1 component, alpha
subunit; n=5; Geobacter|Rep: Dehydrogenase complex, E1
component, alpha subunit - Geobacter sulfurreducens
Length = 325
Score = 54.8 bits (126), Expect = 2e-06
Identities = 29/79 (36%), Positives = 48/79 (60%)
Frame = +1
Query: 4 EYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELV 183
E+ P ++E TYR+ GHSM+DPG YR+ EV E+ ++RDPI +F+++++ +
Sbjct: 228 EWVREHSRPYLIEAMTYRFRGHSMADPG-KYRSAAEV-ELWKSRDPIPNFEKRLVEEGIA 285
Query: 184 TPDQLKDIDAKVRKEVDEA 240
T +L + K R V +A
Sbjct: 286 TEAELAAVLEKCRGVVADA 304
>UniRef50_Q1ARM0 Cluster: Pyruvate dehydrogenase; n=3; Bacteria|Rep:
Pyruvate dehydrogenase - Rubrobacter xylanophilus
(strain DSM 9941 / NBRC 16129)
Length = 332
Score = 54.8 bits (126), Expect = 2e-06
Identities = 23/79 (29%), Positives = 51/79 (64%), Gaps = 2/79 (2%)
Frame = +1
Query: 16 AGKGPLVMEMETYRYSGHSMSDPGTS--YRTRDEVQEVRQTRDPITSFKEKILNHELVTP 189
AG+GP ++E TYR+ GH+ + S YR +E++E + +DPIT+F +++ +
Sbjct: 224 AGEGPSLIEARTYRWHGHNEGEEAFSGPYRPEEEIEEWK-GKDPITTFAARLVEQGVFAR 282
Query: 190 DQLKDIDAKVRKEVDEATK 246
++++ +DA+ ++ +++A +
Sbjct: 283 EEIERVDAEEKERIEDAVR 301
>UniRef50_Q49108 Cluster: Pyruvate dehydrogenase EI alpha subunit;
n=5; Mollicutes|Rep: Pyruvate dehydrogenase EI alpha
subunit - Mycoplasma capricolum
Length = 370
Score = 54.0 bits (124), Expect = 3e-06
Identities = 25/88 (28%), Positives = 51/88 (57%)
Frame = +1
Query: 1 IEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHEL 180
+EY G GP+++E +TYR HS SD +YR + E +E+ + DP+ K+ +++ ++
Sbjct: 242 VEYVRKGNGPVLVECDTYRLGAHSSSDNPDAYRPKGEFEEMAKF-DPLIRLKQYLIDKKI 300
Query: 181 VTPDQLKDIDAKVRKEVDEATKQSKRNQ 264
+ +Q ++A+ K V + ++N+
Sbjct: 301 WSDEQQAQLEAEQDKFVADEFAWVEKNK 328
>UniRef50_Q4DB65 Cluster: 2-oxoisovalerate dehydrogenase alpha
subunit, putative; n=3; Trypanosoma|Rep:
2-oxoisovalerate dehydrogenase alpha subunit, putative -
Trypanosoma cruzi
Length = 431
Score = 54.0 bits (124), Expect = 3e-06
Identities = 35/96 (36%), Positives = 51/96 (53%), Gaps = 2/96 (2%)
Frame = +1
Query: 28 PLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELV-TPDQLKD 204
P+++E YR S HS SD T YR+RDEV+ P+ F EK L +L+ TP+Q +
Sbjct: 314 PVLVEALLYRSSHHSSSDDSTWYRSRDEVEVFSNLFLPVARF-EKYLERKLLWTPEQSRS 372
Query: 205 IDAKVRKE-VDEATKQSKRNQKSVLKSXXPIYTTRT 309
+ KVR+E + E +Q K + V +Y T
Sbjct: 373 LSQKVRQETLAELHRQEKLPKWPVSSMHDDVYKEMT 408
>UniRef50_Q9LPL5 Cluster: Branched-chain alpha keto-acid
dehydrogenase E1-alpha subunit; n=13; Magnoliophyta|Rep:
Branched-chain alpha keto-acid dehydrogenase E1-alpha
subunit - Arabidopsis thaliana (Mouse-ear cress)
Length = 472
Score = 53.6 bits (123), Expect = 3e-06
Identities = 24/83 (28%), Positives = 49/83 (59%)
Frame = +1
Query: 28 PLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQLKDI 207
P+++EM TYR HS SD T YR DE+Q + +R+P+ F++ + ++ + + +
Sbjct: 351 PVLIEMMTYRVGHHSTSDDSTKYRAADEIQYWKMSRNPVNRFRKWVEDNGWWSEEDESKL 410
Query: 208 DAKVRKEVDEATKQSKRNQKSVL 276
+ RK++ +A + +++ +K L
Sbjct: 411 RSNARKQLLQAIQAAEKWEKQPL 433
>UniRef50_Q1KSF1 Cluster: Apicoplast pyruvate dehydrogenase E1 alpha
subunit; n=1; Toxoplasma gondii|Rep: Apicoplast pyruvate
dehydrogenase E1 alpha subunit - Toxoplasma gondii
Length = 635
Score = 53.6 bits (123), Expect = 3e-06
Identities = 28/82 (34%), Positives = 45/82 (54%)
Frame = +1
Query: 1 IEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHEL 180
I+ G+GP ++E TYR+ GHS++DP + +E RDPI SF+E++
Sbjct: 481 IDRARRGEGPTLIEALTYRFRGHSVADPDEMRAVKQ--KEAWVVRDPIKSFEEELKRLGY 538
Query: 181 VTPDQLKDIDAKVRKEVDEATK 246
+ + + AKV+ VD+A K
Sbjct: 539 ASDETIAATRAKVKAVVDDAVK 560
>UniRef50_Q6MAE2 Cluster: Putative pyruvate dehydrogenase
(Lipoamide), E1 component, alpha chain; n=1; Candidatus
Protochlamydia amoebophila UWE25|Rep: Putative pyruvate
dehydrogenase (Lipoamide), E1 component, alpha chain -
Protochlamydia amoebophila (strain UWE25)
Length = 342
Score = 53.2 bits (122), Expect = 5e-06
Identities = 23/71 (32%), Positives = 48/71 (67%)
Frame = +1
Query: 28 PLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQLKDI 207
P+++E+ T R+ GHS+SDPG YR +D ++++ +DPI + + ++ ++T D +K +
Sbjct: 248 PVLVEVVTERFKGHSISDPGL-YRAKDTLKQI-MAKDPILALQAVLIKKGILTEDMVKQM 305
Query: 208 DAKVRKEVDEA 240
+ + R+++ EA
Sbjct: 306 NKENREKIIEA 316
>UniRef50_Q5QUK4 Cluster: Alpha keto acid dehydrogenase complex, E1
component, alpha subunit; n=32; Gammaproteobacteria|Rep:
Alpha keto acid dehydrogenase complex, E1 component,
alpha subunit - Idiomarina loihiensis
Length = 395
Score = 53.2 bits (122), Expect = 5e-06
Identities = 27/77 (35%), Positives = 48/77 (62%)
Frame = +1
Query: 28 PLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQLKDI 207
P+++E +YR SGHS SD T YRTRDE + Q +DP+ ++ + + + D +++
Sbjct: 273 PVLIEAMSYRMSGHSTSDDPTGYRTRDE-EAGWQAKDPLERLQKWMTDEGWLDKDHVEEH 331
Query: 208 DAKVRKEVDEATKQSKR 258
A+V+ +V A K+S++
Sbjct: 332 HAEVKAKVLAALKESEK 348
>UniRef50_A0LLM4 Cluster: Pyruvate dehydrogenase; n=1;
Syntrophobacter fumaroxidans MPOB|Rep: Pyruvate
dehydrogenase - Syntrophobacter fumaroxidans (strain DSM
10017 / MPOB)
Length = 365
Score = 53.2 bits (122), Expect = 5e-06
Identities = 30/87 (34%), Positives = 50/87 (57%), Gaps = 1/87 (1%)
Frame = +1
Query: 1 IEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQE-VRQTRDPITSFKEKILNHE 177
++ AG GP +E TYR S H+ +D YR +EV++ VR RDPI F++ +L
Sbjct: 239 VDRARAGGGPSFIESVTYRLSMHTTADDPKKYRREEEVEQWVR--RDPIIRFEKYLLGRG 296
Query: 178 LVTPDQLKDIDAKVRKEVDEATKQSKR 258
L++ + + I +V+ E+ EA ++ R
Sbjct: 297 LLSEESVAGIADEVQAEIKEAEERWTR 323
>UniRef50_Q97YF6 Cluster: Pyruvate dehydrogenase, alpha subunit
(Lipoamide); n=2; Sulfolobaceae|Rep: Pyruvate
dehydrogenase, alpha subunit (Lipoamide) - Sulfolobus
solfataricus
Length = 345
Score = 53.2 bits (122), Expect = 5e-06
Identities = 31/80 (38%), Positives = 42/80 (52%)
Frame = +1
Query: 1 IEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHEL 180
IE G GP ++E TYRY GH D G YRT++EV E + DPI + ++L
Sbjct: 247 IERARKGFGPTLIEALTYRYVGHFEGD-GEEYRTKEEV-EFWSSLDPIRRLENRLLRLNY 304
Query: 181 VTPDQLKDIDAKVRKEVDEA 240
D L + + RK+V EA
Sbjct: 305 ADSDILARLREEARKQVQEA 324
>UniRef50_Q72GU1 Cluster: 2-oxoisovalerate dehydrogenase subunit
alpha; n=2; Thermus thermophilus|Rep: 2-oxoisovalerate
dehydrogenase subunit alpha - Thermus thermophilus
(strain HB27 / ATCC BAA-163 / DSM 7039)
Length = 367
Score = 53.2 bits (122), Expect = 5e-06
Identities = 25/85 (29%), Positives = 48/85 (56%)
Frame = +1
Query: 1 IEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHEL 180
+E G+GP ++E+ YRY HS +D + YR ++EV R+ +DPI F+ + L
Sbjct: 251 VERARRGEGPSLVELRVYRYGPHSSADDDSRYRPKEEVAFWRK-KDPIPRFRRFLEARGL 309
Query: 181 VTPDQLKDIDAKVRKEVDEATKQSK 255
+ +D+ ++R E++ K+++
Sbjct: 310 WNEEWEEDVREEIRAELERGLKEAE 334
>UniRef50_Q1ATM5 Cluster: Pyruvate dehydrogenase; n=1; Rubrobacter
xylanophilus DSM 9941|Rep: Pyruvate dehydrogenase -
Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 353
Score = 52.8 bits (121), Expect = 6e-06
Identities = 25/80 (31%), Positives = 48/80 (60%)
Frame = +1
Query: 28 PLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQLKDI 207
P +E TYR + H +D YRT++EV++ R RDPI ++K+L + + +++++I
Sbjct: 254 PYAVEAITYRIAPHGAADFFEKYRTKEEVEKWR-ARDPIGILEKKLLERDALDEERIEEI 312
Query: 208 DAKVRKEVDEATKQSKRNQK 267
+ R+ V EA K + +++
Sbjct: 313 KDEARQRVSEAVKYADESEE 332
>UniRef50_Q9RYC1 Cluster: 2-oxo acid dehydrogenase, E1 component,
alpha subunit; n=2; Deinococcus|Rep: 2-oxo acid
dehydrogenase, E1 component, alpha subunit - Deinococcus
radiodurans
Length = 381
Score = 52.4 bits (120), Expect = 8e-06
Identities = 31/88 (35%), Positives = 51/88 (57%), Gaps = 4/88 (4%)
Frame = +1
Query: 4 EYCNAGKGPLVMEMETYRYSGHSMSDPGT--SYRTRDEVQEVRQTRDPITSFKEKILNH- 174
E+ AG GP ++E TYR HS +D SYRTRDEV E RDPI E +L H
Sbjct: 259 EWVRAGNGPALVECLTYRVGSHSNADADAEKSYRTRDEVNE-WLGRDPIQRV-ENLLEHL 316
Query: 175 -ELVTPDQLKDIDAKVRKEVDEATKQSK 255
+ ++ ++ + A++ K++D+ ++++
Sbjct: 317 GDPISAEERAGMIAEIHKQIDDDVRRAE 344
>UniRef50_A7HBV0 Cluster: 3-methyl-2-oxobutanoate dehydrogenase;
n=4; Cystobacterineae|Rep: 3-methyl-2-oxobutanoate
dehydrogenase - Anaeromyxobacter sp. Fw109-5
Length = 399
Score = 52.4 bits (120), Expect = 8e-06
Identities = 28/84 (33%), Positives = 46/84 (54%)
Frame = +1
Query: 4 EYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELV 183
E AG+GP ++E TYR GHS SD +YR E+ E + RDPI + ++ +
Sbjct: 269 ERAEAGEGPTLLECVTYRVEGHSTSDDPRAYRPA-ELVEPWKKRDPILRMRRYLVRRGAL 327
Query: 184 TPDQLKDIDAKVRKEVDEATKQSK 255
+ + I A+VR+E+ K+++
Sbjct: 328 AEAEDERIRAQVREELQRVLKEAE 351
>UniRef50_Q0W151 Cluster: Pyruvate dehydrogenase complex E1,
transketolase alpha subunit; n=1; uncultured
methanogenic archaeon RC-I|Rep: Pyruvate dehydrogenase
complex E1, transketolase alpha subunit - Uncultured
methanogenic archaeon RC-I
Length = 359
Score = 52.4 bits (120), Expect = 8e-06
Identities = 24/80 (30%), Positives = 47/80 (58%)
Frame = +1
Query: 19 GKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQL 198
G+GP +E YR+ H+ SD YR++ EV+++R+ DPI F+ ++N L D+
Sbjct: 245 GEGPAFIEAICYRFGPHTTSDNPDLYRSKGEVEKIRKETDPIDRFRNYLVNKGLWDIDKE 304
Query: 199 KDIDAKVRKEVDEATKQSKR 258
+ ++ +D+A K++++
Sbjct: 305 TRLHDEMDALIDKAAKEAEQ 324
>UniRef50_Q6YPX5 Cluster: Thiamine pyrophosphate-dependent
dehydrogenase, E1 component alpha subunit; n=2;
Candidatus Phytoplasma asteris|Rep: Thiamine
pyrophosphate-dependent dehydrogenase, E1 component
alpha subunit - Onion yellows phytoplasma
Length = 363
Score = 51.6 bits (118), Expect = 1e-05
Identities = 27/100 (27%), Positives = 54/100 (54%)
Frame = +1
Query: 19 GKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQL 198
G GP ++E +YR HS +D + YR+++E E R+ +DPI F++ ++N +T Q+
Sbjct: 246 GNGPTLIENVSYRLEAHSTNDNASVYRSKEEELEWRK-KDPIVRFQKYLMNKGYLTQKQV 304
Query: 199 KDIDAKVRKEVDEATKQSKRNQKSVLKSXXPIYTTRTWNP 318
+ + + ++EV A ++ ++ ++ YT P
Sbjct: 305 EQFEKEAQEEVVLAHQKVEQTGNNIDIKDIFAYTYEKMTP 344
>UniRef50_A6GG24 Cluster: Pyruvate dehydrogenase (Lipoamide), alpha
subunit; n=1; Plesiocystis pacifica SIR-1|Rep: Pyruvate
dehydrogenase (Lipoamide), alpha subunit - Plesiocystis
pacifica SIR-1
Length = 339
Score = 51.6 bits (118), Expect = 1e-05
Identities = 27/71 (38%), Positives = 44/71 (61%)
Frame = +1
Query: 28 PLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQLKDI 207
P ++E+ TYR+ GHSMSDP YR + E++ R +RD I + ++ ++ D+L I
Sbjct: 244 PTLIEILTYRFRGHSMSDP-AKYRAKGELEAFR-SRDAIELSRRVLMEQHGMSEDELDAI 301
Query: 208 DAKVRKEVDEA 240
D +V +E+D A
Sbjct: 302 DDEVIEEMDAA 312
>UniRef50_Q12FH4 Cluster: Pyruvate dehydrogenase; n=37;
Bacteria|Rep: Pyruvate dehydrogenase - Polaromonas sp.
(strain JS666 / ATCC BAA-500)
Length = 337
Score = 51.2 bits (117), Expect = 2e-05
Identities = 28/71 (39%), Positives = 42/71 (59%)
Frame = +1
Query: 28 PLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQLKDI 207
P+ +E++TYR+ HSM DP YR + EVQ +TR PI +F ++ +T D+ +
Sbjct: 243 PVFVELKTYRFRAHSMFDP-ELYRDKAEVQ-AWKTRGPIHTFTARLKAQGSLTEDEFLVL 300
Query: 208 DAKVRKEVDEA 240
DA + EVD A
Sbjct: 301 DAAAQAEVDAA 311
>UniRef50_A6W004 Cluster: Transketolase domain protein; n=6;
Proteobacteria|Rep: Transketolase domain protein -
Marinomonas sp. MWYL1
Length = 701
Score = 51.2 bits (117), Expect = 2e-05
Identities = 23/89 (25%), Positives = 49/89 (55%)
Frame = +1
Query: 1 IEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHEL 180
+EY +GKG ++ ++ R GH+ D T Y+ D + + Q RDP+ K +L++
Sbjct: 251 VEYVRSGKGTCLLRLKVPRLCGHTFQDTQT-YKNEDFIAD-EQARDPLPKLKRYLLDNGF 308
Query: 181 VTPDQLKDIDAKVRKEVDEATKQSKRNQK 267
+T D+ D++ + +++ + ++K Q+
Sbjct: 309 MTADEWHDLEDECYRDIRLSVDKAKERQQ 337
>UniRef50_A4AFX0 Cluster: Acetoin dehydrogenase (TPP-dependent)
alpha chain; n=1; marine actinobacterium PHSC20C1|Rep:
Acetoin dehydrogenase (TPP-dependent) alpha chain -
marine actinobacterium PHSC20C1
Length = 327
Score = 50.8 bits (116), Expect = 2e-05
Identities = 25/55 (45%), Positives = 34/55 (61%)
Frame = +1
Query: 1 IEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKI 165
+E AG+GP ++E +TYR+SGHS SDP YR +EV+ RDPI + I
Sbjct: 231 VERARAGEGPTLIEADTYRHSGHSRSDP-AKYRPEEEVKS-WFARDPIVQLRNAI 283
>UniRef50_Q835M4 Cluster: Pyruvate dehydrogenase complex E1
component, alpha subunit; n=10; Bacilli|Rep: Pyruvate
dehydrogenase complex E1 component, alpha subunit -
Enterococcus faecalis (Streptococcus faecalis)
Length = 371
Score = 50.4 bits (115), Expect = 3e-05
Identities = 31/98 (31%), Positives = 56/98 (57%), Gaps = 5/98 (5%)
Frame = +1
Query: 4 EYCNAGKGPLVMEMETYRYSGHSMS-DPGTSYRTRDEVQEVRQTRDPITSFKEKILNHEL 180
++ AG GP+++E TYRY H++S D T YR+++ E Q +DP+T F++ + + L
Sbjct: 253 DWSAAGNGPVLIETLTYRYGPHTLSGDDPTRYRSKEMDDEWVQ-KDPLTRFRKYLTDKGL 311
Query: 181 VTPDQLKDIDAKVRKEVD----EATKQSKRNQKSVLKS 282
+ + ++I K ++E+ EA K K+ LK+
Sbjct: 312 WSEAKEEEIIEKTKEEIKVAIAEADKAPKQKVSDFLKN 349
>UniRef50_Q8CX87 Cluster: Pyruvate dehydrogenase E1 (Lipoamide)
alpha subunit; n=5; Bacillaceae|Rep: Pyruvate
dehydrogenase E1 (Lipoamide) alpha subunit -
Oceanobacillus iheyensis
Length = 358
Score = 50.0 bits (114), Expect = 4e-05
Identities = 24/82 (29%), Positives = 43/82 (52%)
Frame = +1
Query: 1 IEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHEL 180
+E G+GP ++E T+RY H+ +D T YR + E E + DPIT + + +
Sbjct: 237 LERARNGEGPSLIEAVTWRYGAHTTADDPTKYRNQKEENEKHRQNDPITRLELFMKAYGF 296
Query: 181 VTPDQLKDIDAKVRKEVDEATK 246
++ + +V++E+D A K
Sbjct: 297 WDEAVVEQLKEEVKEEIDGAVK 318
>UniRef50_Q67ME6 Cluster: Branched-chain alpha-keto acid
dehydrogenase E1 alpha subunit; n=23; Bacteria|Rep:
Branched-chain alpha-keto acid dehydrogenase E1 alpha
subunit - Symbiobacterium thermophilum
Length = 352
Score = 50.0 bits (114), Expect = 4e-05
Identities = 26/80 (32%), Positives = 41/80 (51%)
Frame = +1
Query: 4 EYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELV 183
E G+GP ++E R + HS D YR +E+ V Q RDPI ++ + H L+
Sbjct: 252 ERARRGEGPTLIEARCIRITSHSSDDDQRRYRDPEEIAAV-QVRDPIRKARQYLFEHGLM 310
Query: 184 TPDQLKDIDAKVRKEVDEAT 243
++++ KV VD+AT
Sbjct: 311 DEAAEQELERKVAAIVDDAT 330
>UniRef50_Q2JA37 Cluster: Pyruvate dehydrogenase; n=11;
Actinomycetales|Rep: Pyruvate dehydrogenase - Frankia
sp. (strain CcI3)
Length = 388
Score = 50.0 bits (114), Expect = 4e-05
Identities = 21/55 (38%), Positives = 35/55 (63%)
Frame = +1
Query: 1 IEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKI 165
+E+ +G+GP+++E TYR H+ +D T YRT +EV Q RDP+T + ++
Sbjct: 261 VEHARSGRGPVLVEAVTYRLEAHTNADDATRYRTSEEV-AAWQARDPLTLLERQL 314
>UniRef50_Q020J5 Cluster: Dehydrogenase, E1 component; n=1;
Solibacter usitatus Ellin6076|Rep: Dehydrogenase, E1
component - Solibacter usitatus (strain Ellin6076)
Length = 697
Score = 50.0 bits (114), Expect = 4e-05
Identities = 23/88 (26%), Positives = 46/88 (52%)
Frame = +1
Query: 1 IEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHEL 180
+ YC G GP ++ R HS+SD Y+T E + RDP+ F + +++ +
Sbjct: 239 VRYCREGSGPALVHAHCIRPYSHSLSDDERLYKTPAE-RAAEAERDPVLRFPKLLIDEGV 297
Query: 181 VTPDQLKDIDAKVRKEVDEATKQSKRNQ 264
+ L+DI ++ +E+ +AT+ + ++
Sbjct: 298 LDRRMLQDITHEIDEEIQQATQTALHDE 325
>UniRef50_Q9VHB8 Cluster: CG8199-PA; n=2; Eukaryota|Rep: CG8199-PA -
Drosophila melanogaster (Fruit fly)
Length = 439
Score = 49.6 bits (113), Expect = 6e-05
Identities = 29/96 (30%), Positives = 47/96 (48%), Gaps = 4/96 (4%)
Frame = +1
Query: 4 EYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILN---- 171
EY P+V E YR HS SD T+YR +E++ PI+ K +++
Sbjct: 309 EYVLKENKPVVFEALAYRVGHHSTSDDSTAYRPAEEIEIWNSVEHPISKLKRYMVHKGWF 368
Query: 172 HELVTPDQLKDIDAKVRKEVDEATKQSKRNQKSVLK 279
E V + +KDI KV K++ + K+ K N + + +
Sbjct: 369 DETVENEYVKDIRKKVLKQIAVSEKKLKPNWREMFE 404
>UniRef50_Q3E8Q6 Cluster: Uncharacterized protein At5g34780.1; n=1;
Arabidopsis thaliana|Rep: Uncharacterized protein
At5g34780.1 - Arabidopsis thaliana (Mouse-ear cress)
Length = 365
Score = 49.2 bits (112), Expect = 7e-05
Identities = 22/83 (26%), Positives = 47/83 (56%)
Frame = +1
Query: 28 PLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQLKDI 207
P+++EM YR HS SD T YR DE+Q + +R+ + F++ + ++ + + +
Sbjct: 121 PVLIEMMIYRVGHHSTSDDSTKYRAADEIQYWKMSRNSVNRFRKSVEDNGWWSEEDESKL 180
Query: 208 DAKVRKEVDEATKQSKRNQKSVL 276
+ RK++ +A + +++ +K L
Sbjct: 181 RSNARKQLLQAIQAAEKWEKQPL 203
>UniRef50_P37940 Cluster: 2-oxoisovalerate dehydrogenase subunit
alpha; n=37; Firmicutes|Rep: 2-oxoisovalerate
dehydrogenase subunit alpha - Bacillus subtilis
Length = 330
Score = 49.2 bits (112), Expect = 7e-05
Identities = 29/83 (34%), Positives = 47/83 (56%), Gaps = 4/83 (4%)
Frame = +1
Query: 4 EYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSF----KEKILN 171
E G+GP ++E +YR + HS D +SYR R+EV+E +++ DP+ ++ KE L
Sbjct: 231 ERARRGEGPTLIETISYRLTPHSSDDDDSSYRGREEVEEAKKS-DPLLTYQAYLKETGLL 289
Query: 172 HELVTPDQLKDIDAKVRKEVDEA 240
+ + L +I A V + DEA
Sbjct: 290 SDEIEQTMLDEIMAIVNEATDEA 312
>UniRef50_P47516 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha; n=5; Mycoplasma|Rep: Pyruvate
dehydrogenase E1 component subunit alpha - Mycoplasma
genitalium
Length = 358
Score = 48.8 bits (111), Expect = 1e-04
Identities = 21/78 (26%), Positives = 44/78 (56%)
Frame = +1
Query: 7 YCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVT 186
Y G GP+++E +YR H+ SD + YRT+ E +E ++ DP+ + + + ++
Sbjct: 242 YARGGNGPVLIEFFSYRQGPHTTSDDPSIYRTKQEEEEGMKS-DPVKRLRNFLFDRSILN 300
Query: 187 PDQLKDIDAKVRKEVDEA 240
Q +++ +K+ +E+ A
Sbjct: 301 QAQEEEMFSKIEQEIQAA 318
>UniRef50_Q749T8 Cluster: Pyruvate dehydrogenase complex E1
component, alpha subunit; n=4; Geobacter|Rep: Pyruvate
dehydrogenase complex E1 component, alpha subunit -
Geobacter sulfurreducens
Length = 352
Score = 48.4 bits (110), Expect = 1e-04
Identities = 25/77 (32%), Positives = 40/77 (51%)
Frame = +1
Query: 19 GKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQL 198
G GP +E TYR + H+ +D + YR +V+ R RDP+ F+ + L D
Sbjct: 245 GGGPTFIECLTYRMADHTTADDASRYRPPADVEAWRD-RDPLLRFERFLAKRGLWNGDYG 303
Query: 199 KDIDAKVRKEVDEATKQ 249
++ AK E+DEA ++
Sbjct: 304 AEVQAKAEGEIDEAVRR 320
>UniRef50_Q4A1S8 Cluster: Putative uncharacterized protein; n=4;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 432
Score = 47.6 bits (108), Expect = 2e-04
Identities = 26/81 (32%), Positives = 42/81 (51%)
Frame = +1
Query: 28 PLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQLKDI 207
P+++E TYR HS SD T+YR+ DEVQ PIT FK+ I ++ +
Sbjct: 307 PVLIEAMTYRLGHHSTSDDSTAYRSSDEVQTWGDKDHPITRFKKYITERGWWNEEKEMEW 366
Query: 208 DAKVRKEVDEATKQSKRNQKS 270
+V+K V +++ +K+
Sbjct: 367 QKEVKKRVLTEFAAAEKRKKA 387
>UniRef50_Q6A611 Cluster: Pyruvate dehydrogenase E1 component, alpha
subunit; n=1; Propionibacterium acnes|Rep: Pyruvate
dehydrogenase E1 component, alpha subunit -
Propionibacterium acnes
Length = 381
Score = 47.2 bits (107), Expect = 3e-04
Identities = 22/61 (36%), Positives = 34/61 (55%)
Frame = +1
Query: 1 IEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHEL 180
+EY +GKGP+ +E TYR H+ +D T YRT +E +T DPI + + N +
Sbjct: 262 LEYARSGKGPVFVEAWTYRMGAHTTTDDPTRYRTAEEESTWGKT-DPIVRLRTYLQNRGI 320
Query: 181 V 183
+
Sbjct: 321 I 321
>UniRef50_Q4MTG0 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha; n=38; Bacilli|Rep: Pyruvate dehydrogenase
E1 component subunit alpha - Bacillus cereus
Length = 371
Score = 47.2 bits (107), Expect = 3e-04
Identities = 29/79 (36%), Positives = 46/79 (58%), Gaps = 1/79 (1%)
Frame = +1
Query: 19 GKGPLVMEMETYRYSGHSMS-DPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQ 195
G+GP ++E T+RY H+M+ D T YRT+D E Q +DPI F+ + N L +
Sbjct: 258 GEGPTLIETLTFRYGPHTMAGDDPTRYRTKDIENEWEQ-KDPIVRFRAFLENKGLWS--- 313
Query: 196 LKDIDAKVRKEVDEATKQS 252
++++ KV +E E KQ+
Sbjct: 314 -QEVEEKVIEEAKEDIKQA 331
>UniRef50_Q295J7 Cluster: GA20891-PA; n=7; Coelomata|Rep: GA20891-PA
- Drosophila pseudoobscura (Fruit fly)
Length = 439
Score = 46.8 bits (106), Expect = 4e-04
Identities = 27/96 (28%), Positives = 46/96 (47%), Gaps = 4/96 (4%)
Frame = +1
Query: 4 EYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILN---- 171
EY P+V E YR HS SD T+YR+ +E++ PI+ K +++
Sbjct: 309 EYVLRENKPVVFEALAYRVGHHSTSDDSTAYRSTEEIEVWNSVEHPISKLKRYMVHKGWF 368
Query: 172 HELVTPDQLKDIDAKVRKEVDEATKQSKRNQKSVLK 279
E +K++ KV K++ + K+ K N K + +
Sbjct: 369 DEAEETAYIKEVRKKVLKQIAVSEKKLKPNWKEMFE 404
>UniRef50_A6CP23 Cluster: Pyruvate dehydrogenase E1 (Lipoamide)
alpha subunit; n=2; Bacillus sp. SG-1|Rep: Pyruvate
dehydrogenase E1 (Lipoamide) alpha subunit - Bacillus
sp. SG-1
Length = 364
Score = 46.4 bits (105), Expect = 5e-04
Identities = 22/83 (26%), Positives = 40/83 (48%)
Frame = +1
Query: 1 IEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHEL 180
+E G+GP ++E T+RY H+ +D T YR + E E R+ DPI + +
Sbjct: 243 LERARNGEGPTLIEAVTWRYGAHTTADDPTKYRDQSESDERRKLGDPIARLQRYMERQGW 302
Query: 181 VTPDQLKDIDAKVRKEVDEATKQ 249
+ + + E+D+A ++
Sbjct: 303 WDQEWADSVQKEYTAEMDQAVEE 325
>UniRef50_Q3DZ88 Cluster: Dehydrogenase, E1 component; n=1;
Chloroflexus aurantiacus J-10-fl|Rep: Dehydrogenase, E1
component - Chloroflexus aurantiacus J-10-fl
Length = 334
Score = 46.0 bits (104), Expect = 7e-04
Identities = 29/77 (37%), Positives = 45/77 (58%)
Frame = +1
Query: 16 AGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQ 195
+G GP ++E TYR+ GHS SD +YR+RDEV++ Q+RDPI I ++ +
Sbjct: 245 SGYGPTLVEAITYRWKGHSKSD-RQAYRSRDEVKD-WQSRDPIMRLARLI----QMSDAE 298
Query: 196 LKDIDAKVRKEVDEATK 246
K I + R ++EA +
Sbjct: 299 FKAIVDQARTMIEEAVE 315
>UniRef50_A0LFE6 Cluster: Pyruvate dehydrogenase; n=1;
Syntrophobacter fumaroxidans MPOB|Rep: Pyruvate
dehydrogenase - Syntrophobacter fumaroxidans (strain DSM
10017 / MPOB)
Length = 320
Score = 46.0 bits (104), Expect = 7e-04
Identities = 23/77 (29%), Positives = 46/77 (59%)
Frame = +1
Query: 16 AGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQ 195
AG+GP ++E +TYR GH SD Y+ +E+ ++ R P+ ++++L EL+
Sbjct: 227 AGEGPSLIECKTYRCRGHGESD-HQLYQPPEEIASWKE-RCPLPRLRDEVLAQELLDEKA 284
Query: 196 LKDIDAKVRKEVDEATK 246
LK ++ ++ + V++A +
Sbjct: 285 LKSMEDEISRIVEDAVR 301
>UniRef50_P35485 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha; n=2; Firmicutes|Rep: Pyruvate
dehydrogenase E1 component subunit alpha - Acholeplasma
laidlawii
Length = 345
Score = 46.0 bits (104), Expect = 7e-04
Identities = 25/78 (32%), Positives = 45/78 (57%), Gaps = 1/78 (1%)
Frame = +1
Query: 19 GKGPLVMEMETYRYSGHSMS-DPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQ 195
G GP ++E TYR H+ S DP + YRT++E E + +D I FK ++N + ++
Sbjct: 229 GDGPTLIEAFTYRMGPHTTSDDPCSIYRTKEEENEWAK-KDQIARFKTYLINKGYWSEEE 287
Query: 196 LKDIDAKVRKEVDEATKQ 249
K ++ +V E+++ K+
Sbjct: 288 DKKLEEEVLAEINDTFKK 305
>UniRef50_P12694 Cluster: 2-oxoisovalerate dehydrogenase subunit
alpha, mitochondrial precursor; n=29; Euteleostomi|Rep:
2-oxoisovalerate dehydrogenase subunit alpha,
mitochondrial precursor - Homo sapiens (Human)
Length = 445
Score = 46.0 bits (104), Expect = 7e-04
Identities = 26/80 (32%), Positives = 43/80 (53%)
Frame = +1
Query: 28 PLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQLKDI 207
P ++E TYR HS SD ++YR+ DEV + PI+ + +L+ +Q K
Sbjct: 323 PFLIEAMTYRIGHHSTSDDSSAYRSVDEVNYWDKQDHPISRLRHYLLSQGWWDEEQEKAW 382
Query: 208 DAKVRKEVDEATKQSKRNQK 267
+ R++V EA +Q++R K
Sbjct: 383 RKQSRRKVMEAFEQAERKPK 402
>UniRef50_Q9Z8N4 Cluster: Pyruvate Dehydrogenase Alpha; n=8;
Chlamydiaceae|Rep: Pyruvate Dehydrogenase Alpha -
Chlamydia pneumoniae (Chlamydophila pneumoniae)
Length = 342
Score = 45.6 bits (103), Expect = 0.001
Identities = 24/78 (30%), Positives = 49/78 (62%)
Frame = +1
Query: 22 KGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQLK 201
+ P+++E R+ GHS+SDP YR+++E+Q + + +DPI K+ ++ E++T ++ +
Sbjct: 251 ESPVLVECLCSRFRGHSISDPNL-YRSKEEMQCLFK-KDPIVLAKDWLIRLEVLTEEEFQ 308
Query: 202 DIDAKVRKEVDEATKQSK 255
+I + + V EA +K
Sbjct: 309 NIRQECKTAVLEAFSNAK 326
>UniRef50_A3CMZ3 Cluster: Pyruvate dehydrogenase, TPP-dependent E1
component alpha-subunit, putative; n=22; Bacteria|Rep:
Pyruvate dehydrogenase, TPP-dependent E1 component
alpha-subunit, putative - Streptococcus sanguinis
(strain SK36)
Length = 357
Score = 45.6 bits (103), Expect = 0.001
Identities = 25/82 (30%), Positives = 43/82 (52%)
Frame = +1
Query: 1 IEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHEL 180
+E G+GP ++E TYR GH D Y+ + ++ D + F++ + H L
Sbjct: 257 VERARRGEGPTLIEAVTYRDHGHFEGDE-QKYKALEGEEKDWADVDALDVFRDYAIEHGL 315
Query: 181 VTPDQLKDIDAKVRKEVDEATK 246
+T ++L I + RK+V+EA K
Sbjct: 316 LTEEELDAILEESRKDVEEAIK 337
>UniRef50_Q8YDW3 Cluster: 2-OXOISOVALERATE DEHYDROGENASE BETA
SUBUNIT; n=10; Bacteria|Rep: 2-OXOISOVALERATE
DEHYDROGENASE BETA SUBUNIT - Brucella melitensis
Length = 729
Score = 45.2 bits (102), Expect = 0.001
Identities = 25/80 (31%), Positives = 43/80 (53%), Gaps = 2/80 (2%)
Frame = +1
Query: 16 AGKGPLVMEMETYRYSGHSMSDPGTS--YRTRDEVQEVRQTRDPITSFKEKILNHELVTP 189
AG GP ++E + YRY + PG++ YR++DE E R RDP+ + + +L + +
Sbjct: 269 AGNGPTIIEADVYRYFHQNGPLPGSAFGYRSKDEEAEWR-GRDPLDALAKTLLERQALGE 327
Query: 190 DQLKDIDAKVRKEVDEATKQ 249
D +K + + +DE Q
Sbjct: 328 DAIKALRERCVSLMDEVAGQ 347
>UniRef50_Q5KUY4 Cluster: Pyruvate dehydrogenase E1 (Lipoamide)
alpha subunit; n=2; Geobacillus|Rep: Pyruvate
dehydrogenase E1 (Lipoamide) alpha subunit - Geobacillus
kaustophilus
Length = 359
Score = 45.2 bits (102), Expect = 0.001
Identities = 26/80 (32%), Positives = 41/80 (51%)
Frame = +1
Query: 1 IEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHEL 180
+E G+GP+++E TYR H+ +D T YR +EV E + +DP+ + + L
Sbjct: 237 VEAARRGEGPMLIEALTYRLGPHTTADDPTKYRRPEEV-ETWRAKDPLRRLRLLLERRGL 295
Query: 181 VTPDQLKDIDAKVRKEVDEA 240
T Q + A+V EV A
Sbjct: 296 WTEAQEDALVAQVNDEVTAA 315
>UniRef50_Q02C52 Cluster: Pyruvate dehydrogenase; n=1; Solibacter
usitatus Ellin6076|Rep: Pyruvate dehydrogenase -
Solibacter usitatus (strain Ellin6076)
Length = 340
Score = 45.2 bits (102), Expect = 0.001
Identities = 23/87 (26%), Positives = 48/87 (55%)
Frame = +1
Query: 1 IEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHEL 180
+ + G GP ++E +T+R +GHS D T Y + +E + DPI ++++L
Sbjct: 240 VTHARGGLGPYLLECKTFRMTGHSAHDAAT-YVPKGLFEEWGKL-DPIVRLEKRMLEERW 297
Query: 181 VTPDQLKDIDAKVRKEVDEATKQSKRN 261
+++ ++ A V +EVD+A ++++
Sbjct: 298 SLQEEIDELHAAVIREVDDAVAWAEQS 324
>UniRef50_Q8SQM8 Cluster: PYRUVATE DEHYDROGENASE E1 COMPONENT ALPHA
SUBUNIT; n=1; Encephalitozoon cuniculi|Rep: PYRUVATE
DEHYDROGENASE E1 COMPONENT ALPHA SUBUNIT -
Encephalitozoon cuniculi
Length = 349
Score = 45.2 bits (102), Expect = 0.001
Identities = 26/76 (34%), Positives = 46/76 (60%), Gaps = 2/76 (2%)
Frame = +1
Query: 25 GPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILN-HELVTPDQLK 201
GP++++++TYR+ HS +D SYR+R+EV + + RD + ++L + D L+
Sbjct: 260 GPIIVQIDTYRFCTHSAADERESYRSREEV-DAEKKRDCMEDVGRRLLAFYSEEELDALR 318
Query: 202 -DIDAKVRKEVDEATK 246
I A+V ++VD A K
Sbjct: 319 SSILAEVERDVDAARK 334
>UniRef50_Q67SE7 Cluster: Pyruvate dehydrogenase E1 alpha subunit;
n=2; Bacilli|Rep: Pyruvate dehydrogenase E1 alpha
subunit - Symbiobacterium thermophilum
Length = 368
Score = 44.8 bits (101), Expect = 0.002
Identities = 21/48 (43%), Positives = 31/48 (64%)
Frame = +1
Query: 1 IEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPI 144
IE +G GP ++E T+RY H+ SD YR+++E++E Q RDPI
Sbjct: 243 IERARSGGGPTLVESVTFRYGPHTTSDDPKRYRSQEELEE-WQARDPI 289
>UniRef50_A5IXN2 Cluster: Pyruvate dehydrogenase E1 component,
alphasubunit; n=1; Mycoplasma agalactiae|Rep: Pyruvate
dehydrogenase E1 component, alphasubunit - Mycoplasma
agalactiae
Length = 363
Score = 44.8 bits (101), Expect = 0.002
Identities = 24/83 (28%), Positives = 43/83 (51%)
Frame = +1
Query: 7 YCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVT 186
Y G GP+++EM T+R H+ SD YR+R E++ ++ +P + +L+ +L+T
Sbjct: 246 YVREGNGPVLVEMVTWRQGQHTTSDNPRVYRSR-ELEMEKEKWEPFHRIEAYLLSEKLIT 304
Query: 187 PDQLKDIDAKVRKEVDEATKQSK 255
+ +K +E A SK
Sbjct: 305 EEDIKVWSEAAAEEAKAAYALSK 327
>UniRef50_Q97CK0 Cluster: 2-oxoisovalerate dehydrogenase alpha
subunit; n=2; Thermoplasma|Rep: 2-oxoisovalerate
dehydrogenase alpha subunit - Thermoplasma volcanium
Length = 337
Score = 44.8 bits (101), Expect = 0.002
Identities = 27/105 (25%), Positives = 54/105 (51%), Gaps = 1/105 (0%)
Frame = +1
Query: 1 IEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHEL 180
+EY +G P+++E +YR HS SD + YR ++EV+E DP+ ++ +++ +
Sbjct: 224 VEYARSGN-PILVEARSYRMGPHSTSDDPSKYR-QNEVKE-GDENDPLVIAEKAVISKGI 280
Query: 181 VTPDQLKDIDAKVRKEVDEATKQS-KRNQKSVLKSXXPIYTTRTW 312
++ ++ I + RK +DE ++ K +Y+ TW
Sbjct: 281 LSQSEVNRIKDESRKMIDEKFEERLKIPAPDPSTLFDDVYSETTW 325
>UniRef50_A7K3C9 Cluster: Dehydrogenase E1 component superfamily;
n=10; Gammaproteobacteria|Rep: Dehydrogenase E1
component superfamily - Vibrio sp. Ex25
Length = 398
Score = 44.4 bits (100), Expect = 0.002
Identities = 25/83 (30%), Positives = 43/83 (51%)
Frame = +1
Query: 1 IEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHEL 180
+E GKG ++E +YR S H+ +D T YR D+VQ Q +PI K +LN
Sbjct: 273 LERARKGKGATLIEAVSYRLSDHTTADDATRYRKEDDVQTAWQ-YEPIARLKTYLLNQGA 331
Query: 181 VTPDQLKDIDAKVRKEVDEATKQ 249
+ +Q + +++V+ A ++
Sbjct: 332 WSDEQEQQWLEYCKEQVELAVER 354
>UniRef50_P21873 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha; n=33; Bacilli|Rep: Pyruvate dehydrogenase
E1 component subunit alpha - Bacillus stearothermophilus
(Geobacillus stearothermophilus)
Length = 369
Score = 44.4 bits (100), Expect = 0.002
Identities = 23/84 (27%), Positives = 48/84 (57%), Gaps = 1/84 (1%)
Frame = +1
Query: 19 GKGPLVMEMETYRYSGHSMS-DPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQ 195
G+GP ++E +RY H+MS D T YR++ E++ +DP+ F++ + L + ++
Sbjct: 256 GEGPTLIETLCFRYGPHTMSGDDPTRYRSK-ELENEWAKKDPLVRFRKFLEAKGLWSEEE 314
Query: 196 LKDIDAKVRKEVDEATKQSKRNQK 267
++ + ++E+ EA K++ K
Sbjct: 315 ENNVIEQAKEEIKEAIKKADETPK 338
>UniRef50_Q7NLM8 Cluster: Gll1094 protein; n=1; Gloeobacter
violaceus|Rep: Gll1094 protein - Gloeobacter violaceus
Length = 481
Score = 44.0 bits (99), Expect = 0.003
Identities = 22/80 (27%), Positives = 42/80 (52%)
Frame = +1
Query: 19 GKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQL 198
G GP ++ +E R H+ SD YR ++E+ + Q RDP++ ++N +T +
Sbjct: 225 GNGPTILWVELDRLVSHTNSDDHRIYRPKEEIDAMLQ-RDPLSVLARHLINAGELTATEW 283
Query: 199 KDIDAKVRKEVDEATKQSKR 258
+ + K +DE +Q++R
Sbjct: 284 QALQFKTAMTIDEIYQQAER 303
>UniRef50_Q3DYK5 Cluster: Dehydrogenase, E1 component; n=3;
Bacteria|Rep: Dehydrogenase, E1 component - Chloroflexus
aurantiacus J-10-fl
Length = 321
Score = 44.0 bits (99), Expect = 0.003
Identities = 25/80 (31%), Positives = 44/80 (55%)
Frame = +1
Query: 1 IEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHEL 180
+E AG GP +E +T R GH++ D +Y ++ + E + RDPI +E + + L
Sbjct: 223 VERARAGGGPTFIECKTMRMRGHAIHD-NMAYVPKELLAE-WEARDPIARIEEVLRSRGL 280
Query: 181 VTPDQLKDIDAKVRKEVDEA 240
+ +L + A++ E+DEA
Sbjct: 281 LDDAKLAALLARIEAELDEA 300
>UniRef50_A4F1Y5 Cluster: Branched-chain alpha-keto acid
decarboxylase; n=1; Streptomyces virginiae|Rep:
Branched-chain alpha-keto acid decarboxylase -
Streptomyces virginiae
Length = 677
Score = 44.0 bits (99), Expect = 0.003
Identities = 22/74 (29%), Positives = 38/74 (51%)
Frame = +1
Query: 16 AGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQ 195
AG+GP V+ R H+ SD YRT+DE+ + RDP+ F +++ + P
Sbjct: 247 AGRGPAVLWCRLDRLDSHTSSDDQRLYRTKDELAAM---RDPVALFTDRLEAEGTIVPGW 303
Query: 196 LKDIDAKVRKEVDE 237
+ A++ +V+E
Sbjct: 304 ADQVRARLADDVEE 317
>UniRef50_A0UXT3 Cluster: Pyruvate dehydrogenase; n=1; Clostridium
cellulolyticum H10|Rep: Pyruvate dehydrogenase -
Clostridium cellulolyticum H10
Length = 321
Score = 44.0 bits (99), Expect = 0.003
Identities = 24/82 (29%), Positives = 46/82 (56%), Gaps = 2/82 (2%)
Frame = +1
Query: 1 IEYCNAGKGPLVMEMETYRYSGH--SMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNH 174
IE C G+GP ++E +YR+ GH ++ D G YR+++E + ++ PI +K+ +
Sbjct: 219 IERCRKGEGPTLLECVSYRWKGHIGTVDDLGVGYRSQEE-YDYWISKCPIKWYKDYLRVR 277
Query: 175 ELVTPDQLKDIDAKVRKEVDEA 240
++ K I+ ++ K V +A
Sbjct: 278 NILDDKLEKSINEEIDKLVKDA 299
>UniRef50_Q4P2J0 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 786
Score = 44.0 bits (99), Expect = 0.003
Identities = 22/85 (25%), Positives = 46/85 (54%)
Frame = +1
Query: 28 PLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQLKDI 207
P+++E TYR HS SD ++YR++ V+ +Q +P+ + + + + ++
Sbjct: 648 PVLIEAMTYRVGHHSTSDDSSAYRSKQAVESWKQMDNPLHRMRNYLTDRGWWNDELEEET 707
Query: 208 DAKVRKEVDEATKQSKRNQKSVLKS 282
A RK+V EA ++++ ++ L S
Sbjct: 708 KAGHRKKVIEAMARAEKKKRPKLSS 732
>UniRef50_Q8ZUR8 Cluster: Pyruvate dehydrogenase E1 alpha subunit;
n=3; Pyrobaculum|Rep: Pyruvate dehydrogenase E1 alpha
subunit - Pyrobaculum aerophilum
Length = 372
Score = 44.0 bits (99), Expect = 0.003
Identities = 25/86 (29%), Positives = 47/86 (54%), Gaps = 1/86 (1%)
Frame = +1
Query: 1 IEYCNAGKGPLVMEMETYRYSGHSMSD-PGTSYRTRDEVQEVRQTRDPITSFKEKILNHE 177
+E G+ P ++E YR+ H+ +D P T YR EV+E R+ DP+ ++ ++
Sbjct: 260 VEKARRGE-PTLVEYVMYRFGPHTTADDPLTKYRDPKEVEEYRRW-DPLARLEKFLIRQG 317
Query: 178 LVTPDQLKDIDAKVRKEVDEATKQSK 255
+ + +K I + +EV EA K+++
Sbjct: 318 IYSEGDVKTIWEEAEREVKEAAKEAE 343
>UniRef50_Q2J998 Cluster: Pyruvate dehydrogenase; n=1; Frankia sp.
CcI3|Rep: Pyruvate dehydrogenase - Frankia sp. (strain
CcI3)
Length = 417
Score = 43.6 bits (98), Expect = 0.004
Identities = 19/48 (39%), Positives = 30/48 (62%)
Frame = +1
Query: 1 IEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPI 144
++ +G+GP+++E TYR + H+ SD T Y+ DE+ Q RDPI
Sbjct: 299 LDRARSGRGPVLIEANTYRMAPHTTSDDATRYQPPDEI-TAWQARDPI 345
>UniRef50_Q3WCG3 Cluster: Pyruvate dehydrogenase; n=4;
Actinomycetales|Rep: Pyruvate dehydrogenase - Frankia
sp. EAN1pec
Length = 332
Score = 43.2 bits (97), Expect = 0.005
Identities = 23/80 (28%), Positives = 41/80 (51%)
Frame = +1
Query: 1 IEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHEL 180
+E +G GP ++E T+R+ GH DP +Y + + + DPI F+ ++L +
Sbjct: 227 VERARSGGGPTLVECVTFRFRGHYFGDP-MAYIPAERMAAAVEA-DPIPRFRSRLLETGV 284
Query: 181 VTPDQLKDIDAKVRKEVDEA 240
+L +I+A V+EA
Sbjct: 285 CDEHELDEIEAAAVAAVEEA 304
>UniRef50_Q2ITF8 Cluster: Acetoin dehydrogenase (TPP-dependent)
alpha chain; n=1; Rhodopseudomonas palustris HaA2|Rep:
Acetoin dehydrogenase (TPP-dependent) alpha chain -
Rhodopseudomonas palustris (strain HaA2)
Length = 323
Score = 43.2 bits (97), Expect = 0.005
Identities = 24/77 (31%), Positives = 40/77 (51%), Gaps = 2/77 (2%)
Frame = +1
Query: 16 AGKGPLVMEMETYRYSGHSMS--DPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTP 189
AG+GP E ETYR+ H D YR+ E E + RDP+ + + ++ +V+
Sbjct: 224 AGEGPRFYEFETYRWREHCGPNYDNDIGYRSAAEY-EAWKLRDPVPALQRALIGEGVVSE 282
Query: 190 DQLKDIDAKVRKEVDEA 240
+ + A++ E+DEA
Sbjct: 283 SGIAAMQAEIDAEIDEA 299
>UniRef50_A7BPK6 Cluster: Pyruvate dehydrogenase; n=1; Beggiatoa sp.
PS|Rep: Pyruvate dehydrogenase - Beggiatoa sp. PS
Length = 331
Score = 43.2 bits (97), Expect = 0.005
Identities = 22/76 (28%), Positives = 41/76 (53%), Gaps = 2/76 (2%)
Frame = +1
Query: 19 GKGPLVMEMETYRYSGH--SMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPD 192
G+GP +E++TYR+ H D YR E+ ++ R P+ FK +L + VT
Sbjct: 235 GEGPQFLELDTYRWLEHCGPNDDDNLGYRPAGELMSWKK-RCPVEQFKNLLLESQKVTHT 293
Query: 193 QLKDIDAKVRKEVDEA 240
+++ ++ +V E++ A
Sbjct: 294 EIQQVENEVLHEIEAA 309
>UniRef50_Q5VGY4 Cluster: Pyruvate dehydrogenase alpha subunit; n=6;
Plasmodium|Rep: Pyruvate dehydrogenase alpha subunit -
Plasmodium falciparum
Length = 608
Score = 43.2 bits (97), Expect = 0.005
Identities = 23/85 (27%), Positives = 42/85 (49%)
Frame = +1
Query: 13 NAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPD 192
N GP+++E TYR GHS++DP R ++E ++ RDPI + + LV
Sbjct: 448 NRTSGPIIIEAITYRAKGHSLADP-DELRIKEEKTSWKK-RDPILFLSSYMKKYNLVQES 505
Query: 193 QLKDIDAKVRKEVDEATKQSKRNQK 267
+ + + + +A +++N K
Sbjct: 506 YFEQVKKNTQTLLQQAELDAEQNTK 530
>UniRef50_Q53610 Cluster: Branched-chain alpha-keto acid
dehydrogenase E1-alpha subunit; n=16;
Actinomycetales|Rep: Branched-chain alpha-keto acid
dehydrogenase E1-alpha subunit - Streptomyces
avermitilis
Length = 406
Score = 42.7 bits (96), Expect = 0.006
Identities = 20/48 (41%), Positives = 28/48 (58%)
Frame = +1
Query: 1 IEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPI 144
+E G+GP ++E TYR H+ SD T YR DE +E + +DPI
Sbjct: 272 LERARRGEGPTLVEAFTYRMGAHTTSDDPTKYRA-DEEREAWEAKDPI 318
>UniRef50_Q319T4 Cluster: Pyruvate dehydrogenase; n=1;
Prochlorococcus marinus str. MIT 9312|Rep: Pyruvate
dehydrogenase - Prochlorococcus marinus (strain MIT
9312)
Length = 347
Score = 42.7 bits (96), Expect = 0.006
Identities = 25/84 (29%), Positives = 45/84 (53%), Gaps = 4/84 (4%)
Frame = +1
Query: 1 IEYCNAGKGPLVMEMETYRYSGH----SMSDPGTSYRTRDEVQEVRQTRDPITSFKEKIL 168
I C G+GP +E TYR+ GH D G + R+ D+++ ++ RDPI K+ +L
Sbjct: 241 IRRCRDGEGPFFIEALTYRWFGHVDWREDIDVGIN-RSADDLKYWKK-RDPILRLKKSLL 298
Query: 169 NHELVTPDQLKDIDAKVRKEVDEA 240
+ L +++ ++K++D A
Sbjct: 299 KENYFGENHLINLEKDIQKDIDNA 322
>UniRef50_Q5SJR9 Cluster: Pyruvate dehydrogenase (Lipoamide) (EC
1.2.4.1) E1-alpha chain; n=2; Thermus thermophilus|Rep:
Pyruvate dehydrogenase (Lipoamide) (EC 1.2.4.1) E1-alpha
chain - Thermus thermophilus (strain HB8 / ATCC 27634 /
DSM 579)
Length = 346
Score = 42.3 bits (95), Expect = 0.009
Identities = 18/55 (32%), Positives = 34/55 (61%)
Frame = +1
Query: 1 IEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKI 165
+E G+GP ++E TYR + H+ SD + YR+++E +E + +DPI ++ +
Sbjct: 224 VERARKGEGPTLLEALTYRLAPHTTSDDPSRYRSKEE-EEAWRAKDPILRLRKAL 277
>UniRef50_Q00TN9 Cluster: Pyruvate dehydrogenase E1 component beta;
n=3; Ostreococcus|Rep: Pyruvate dehydrogenase E1
component beta - Ostreococcus tauri
Length = 835
Score = 42.3 bits (95), Expect = 0.009
Identities = 17/45 (37%), Positives = 28/45 (62%)
Frame = +1
Query: 22 KGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFK 156
KGP ++++ T+R++GHS +DP +DE + R DPI F+
Sbjct: 363 KGPAILQVHTFRFNGHSPADPEHERNRKDEKRWARAECDPIKIFE 407
>UniRef50_A3SJ75 Cluster: 2-oxoisovalerate dehydrogenase beta
subunit; n=1; Roseovarius nubinhibens ISM|Rep:
2-oxoisovalerate dehydrogenase beta subunit -
Roseovarius nubinhibens ISM
Length = 746
Score = 41.9 bits (94), Expect = 0.011
Identities = 22/72 (30%), Positives = 40/72 (55%), Gaps = 1/72 (1%)
Frame = +1
Query: 25 GPLVMEMETYRYSGHSMSDPGTSYRTRDEVQE-VRQTRDPITSFKEKILNHELVTPDQLK 201
GP+++E TYR+ S G+++ RD+ +E RDP T+ ++IL L+T Q+
Sbjct: 287 GPVLLEARTYRHLHQSGPLKGSAFGYRDKAEEDAWLARDPATTLPQQILRAGLLTEAQID 346
Query: 202 DIDAKVRKEVDE 237
+ ++ VD+
Sbjct: 347 TLRSRATAAVDD 358
>UniRef50_A1UJ85 Cluster: Pyruvate dehydrogenase; n=16;
Mycobacterium|Rep: Pyruvate dehydrogenase -
Mycobacterium sp. (strain KMS)
Length = 356
Score = 41.9 bits (94), Expect = 0.011
Identities = 21/47 (44%), Positives = 27/47 (57%)
Frame = +1
Query: 16 AGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFK 156
AG GP ++E TYR H+ SD T YR + EV R RDPI ++
Sbjct: 241 AGGGPTLIEAVTYRLGPHTTSDDPTRYRDQSEVDRWR-ARDPIPRYR 286
>UniRef50_Q3W421 Cluster: Pyruvate dehydrogenase; n=1; Frankia sp.
EAN1pec|Rep: Pyruvate dehydrogenase - Frankia sp.
EAN1pec
Length = 358
Score = 41.5 bits (93), Expect = 0.015
Identities = 19/48 (39%), Positives = 30/48 (62%)
Frame = +1
Query: 1 IEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPI 144
+E+ +G+GP+++E TYR + H+ SD + Y+ EV R RDPI
Sbjct: 245 LEHARSGQGPVLIEANTYRMAPHTTSDDASRYQEAAEVAAWR-ARDPI 291
>UniRef50_A3TUC4 Cluster: TPP-dependent acetoin dehydrogenase
complex, E1 component, alpha subunit; n=1; Oceanicola
batsensis HTCC2597|Rep: TPP-dependent acetoin
dehydrogenase complex, E1 component, alpha subunit -
Oceanicola batsensis HTCC2597
Length = 86
Score = 41.1 bits (92), Expect = 0.020
Identities = 22/68 (32%), Positives = 37/68 (54%)
Frame = +1
Query: 43 METYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQLKDIDAKVR 222
METYR +GH M D YR E + + +DPI + + ++L + ++L I+A+
Sbjct: 1 METYRLAGHFMGD-AEGYRPEGEKDGLFE-KDPIPAMRARLLKDGAASEEELAAIEAEAE 58
Query: 223 KEVDEATK 246
V++A K
Sbjct: 59 ARVEKAIK 66
>UniRef50_A0M1U4 Cluster: 2-oxoisovalerate dehydrogenase E1
component subunits alpha and beta; n=18;
Bacteroidetes|Rep: 2-oxoisovalerate dehydrogenase E1
component subunits alpha and beta - Gramella forsetii
(strain KT0803)
Length = 685
Score = 41.1 bits (92), Expect = 0.020
Identities = 19/70 (27%), Positives = 42/70 (60%)
Frame = +1
Query: 28 PLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQLKDI 207
P+++E +T+R GH + GT Y ++ + E +Q +DP+ +F+E ++ ++T D +
Sbjct: 261 PVLVEFKTFRMRGHEEAS-GTKYVPQELMDEWQQ-KDPVLNFEEYLIAKNILTNDLKEKF 318
Query: 208 DAKVRKEVDE 237
++ E+D+
Sbjct: 319 RTEILAEIDK 328
>UniRef50_A0K283 Cluster: Pyruvate dehydrogenase; n=4;
Actinobacteria (class)|Rep: Pyruvate dehydrogenase -
Arthrobacter sp. (strain FB24)
Length = 415
Score = 40.7 bits (91), Expect = 0.026
Identities = 23/64 (35%), Positives = 33/64 (51%)
Frame = +1
Query: 1 IEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHEL 180
+E GK P+++E TYR H+ +D T YR DE + R +DP+ EK L E
Sbjct: 279 LERAREGKSPVLIEAFTYRVGAHTTADDPTKYRGSDEEAQWR-AKDPLERL-EKYLRAEG 336
Query: 181 VTPD 192
+ D
Sbjct: 337 MADD 340
>UniRef50_A6WG12 Cluster: Pyruvate dehydrogenase; n=3;
Actinomycetales|Rep: Pyruvate dehydrogenase -
Kineococcus radiotolerans SRS30216
Length = 390
Score = 40.3 bits (90), Expect = 0.035
Identities = 26/79 (32%), Positives = 39/79 (49%)
Frame = +1
Query: 1 IEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHEL 180
+E +G GP +E TYR H+ +D T YR E + R+ +DPI F+ L E
Sbjct: 257 LERARSGGGPTFVEAFTYRMGAHTTADDPTRYRLSAETEAWRE-KDPIDRFR-TYLRAEG 314
Query: 181 VTPDQLKDIDAKVRKEVDE 237
+ D + +A + E DE
Sbjct: 315 ILDD---EYEAALAAEADE 330
>UniRef50_Q8EVQ2 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha; n=1; Mycoplasma penetrans|Rep: Pyruvate
dehydrogenase E1 component subunit alpha - Mycoplasma
penetrans
Length = 359
Score = 39.9 bits (89), Expect = 0.046
Identities = 24/80 (30%), Positives = 40/80 (50%)
Frame = +1
Query: 7 YCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVT 186
Y K P+++E TYR H+ SD YR+ +E + ++ +DPI + + + L+
Sbjct: 241 YVLENKKPILVEFVTYRKGPHTTSDNPRIYRS-EEYECEQEKKDPILRLERWMAQNGLLD 299
Query: 187 PDQLKDIDAKVRKEVDEATK 246
+ I K EV+EA K
Sbjct: 300 ESKKAQIIEKADAEVEEAYK 319
>UniRef50_Q9YBC0 Cluster: Pyruvate dehydrogenase E1 component, alpha
subunit; n=1; Aeropyrum pernix|Rep: Pyruvate
dehydrogenase E1 component, alpha subunit - Aeropyrum
pernix
Length = 377
Score = 39.9 bits (89), Expect = 0.046
Identities = 19/82 (23%), Positives = 43/82 (52%)
Frame = +1
Query: 4 EYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELV 183
E G GP ++E TYR H+ +D + YRT +E + + + +P+ ++ + + ++
Sbjct: 250 EKARRGGGPTLIEAVTYRLGPHTTADDPSRYRTSEE-ERIMERYEPLRRMRKFMESMGIL 308
Query: 184 TPDQLKDIDAKVRKEVDEATKQ 249
T + I+ + +V+E ++
Sbjct: 309 TEKEALSIEEEWNSKVEEIVRK 330
>UniRef50_Q8YDG0 Cluster: 2-OXOISOVALERATE DEHYDROGENASE BETA
SUBUNIT; n=3; Brucella|Rep: 2-OXOISOVALERATE
DEHYDROGENASE BETA SUBUNIT - Brucella melitensis
Length = 725
Score = 39.5 bits (88), Expect = 0.060
Identities = 24/74 (32%), Positives = 39/74 (52%), Gaps = 2/74 (2%)
Frame = +1
Query: 25 GPLVMEMETYRYSGHSMSDPGT--SYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQL 198
GP+V+E + YRY S S G+ YRTR+E +E + +RDPI + ++ + +
Sbjct: 273 GPVVIEAQCYRYLHQSGSKSGSDFGYRTREEEEEWK-SRDPIALAERRLKELGIAGDAEF 331
Query: 199 KDIDAKVRKEVDEA 240
+D +V V A
Sbjct: 332 LKLDERVTAAVQAA 345
>UniRef50_Q83FF2 Cluster: Pyruvate dehydrogenase E1 component alpha
subunit; n=2; Tropheryma whipplei|Rep: Pyruvate
dehydrogenase E1 component alpha subunit - Tropheryma
whipplei (strain Twist) (Whipple's bacillus)
Length = 370
Score = 39.5 bits (88), Expect = 0.060
Identities = 17/40 (42%), Positives = 25/40 (62%)
Frame = +1
Query: 1 IEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQE 120
++ +GKGP ++E TYR H+ SD T YR+ DE +E
Sbjct: 252 MDRARSGKGPHLIEAFTYRLGAHTTSDDPTRYRSEDEHRE 291
>UniRef50_Q5KGR5 Cluster: Branched-chain alpha-keto acid
dehydrogenase E1-alpha subunit, putative; n=2;
Filobasidiella neoformans|Rep: Branched-chain alpha-keto
acid dehydrogenase E1-alpha subunit, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 504
Score = 39.5 bits (88), Expect = 0.060
Identities = 23/86 (26%), Positives = 46/86 (53%)
Frame = +1
Query: 19 GKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQL 198
GK +++E TYR HS SD + YR +EV+E +PI + +++ + + ++
Sbjct: 356 GKKGVLVEAMTYRVGHHSTSDDSSMYRAIEEVKEWSVVDNPIHRLRSYLVSKKWWSEEEE 415
Query: 199 KDIDAKVRKEVDEATKQSKRNQKSVL 276
K + K + +V +A ++++ K L
Sbjct: 416 KALLKKNKADVLKAFSRAEKLPKPKL 441
>UniRef50_A3RZM3 Cluster: Pyruvate dehydrogenase E1 component alpha
subunit; n=5; Proteobacteria|Rep: Pyruvate dehydrogenase
E1 component alpha subunit - Ralstonia solanacearum
UW551
Length = 368
Score = 39.1 bits (87), Expect = 0.080
Identities = 21/80 (26%), Positives = 38/80 (47%)
Frame = +1
Query: 1 IEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHEL 180
++ AG GP ++E +YR H+ +D T YR D V++ R+PI + ++
Sbjct: 238 LDKARAGGGPTLIEALSYRLGDHTTADDATRYRDSDIVKQA-WAREPILRLRNYLVRQNA 296
Query: 181 VTPDQLKDIDAKVRKEVDEA 240
Q + + +V+EA
Sbjct: 297 WDKAQEEQLGRACYAQVEEA 316
>UniRef50_Q95VS6 Cluster: Pyruvate dehydrogenase E1 alpha subunit;
n=2; Antonospora locustae|Rep: Pyruvate dehydrogenase E1
alpha subunit - Antonospora locustae (Nosema locustae)
Length = 342
Score = 39.1 bits (87), Expect = 0.080
Identities = 17/36 (47%), Positives = 25/36 (69%)
Frame = +1
Query: 22 KGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQ 129
KGPL+++++TYR GHS +D G YR EV+ R+
Sbjct: 252 KGPLIVQIDTYRLCGHSTTD-GIVYRDETEVRRERE 286
>UniRef50_UPI00005103B4 Cluster: COG1071: Pyruvate/2-oxoglutarate
dehydrogenase complex, dehydrogenase (E1) component,
eukaryotic type, alpha subunit; n=1; Brevibacterium
linens BL2|Rep: COG1071: Pyruvate/2-oxoglutarate
dehydrogenase complex, dehydrogenase (E1) component,
eukaryotic type, alpha subunit - Brevibacterium linens
BL2
Length = 368
Score = 38.7 bits (86), Expect = 0.11
Identities = 19/42 (45%), Positives = 25/42 (59%)
Frame = +1
Query: 19 GKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPI 144
G GP ++E TYR H+ SD T YR +EV+ +Q DPI
Sbjct: 252 GDGPTLIECLTYRMESHTNSDDPTKYRDSEEVEHWKQF-DPI 292
>UniRef50_Q4L1A7 Cluster: Pyruvate dehydrogenase E1 component alpha
subunit; n=9; Mycoplasma|Rep: Pyruvate dehydrogenase E1
component alpha subunit - Mycoplasma synoviae
Length = 374
Score = 38.7 bits (86), Expect = 0.11
Identities = 21/92 (22%), Positives = 49/92 (53%)
Frame = +1
Query: 1 IEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHEL 180
+E+ P+++E T+R H+ SD YRT E +E ++ +P+ ++ +L+ +L
Sbjct: 252 VEFARKESRPVLVEFVTWRQGPHTTSDNPRVYRTETEEKE-QEVWEPMHRIEKYLLDRKL 310
Query: 181 VTPDQLKDIDAKVRKEVDEATKQSKRNQKSVL 276
+T +++ I A + + ++S + ++ L
Sbjct: 311 LTKKEIEKIWADSLEVAKKTYEESVKLNEATL 342
>UniRef50_A0JY23 Cluster: Pyruvate dehydrogenase; n=2;
Arthrobacter|Rep: Pyruvate dehydrogenase - Arthrobacter
sp. (strain FB24)
Length = 359
Score = 38.7 bits (86), Expect = 0.11
Identities = 19/54 (35%), Positives = 31/54 (57%)
Frame = +1
Query: 7 YCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKIL 168
+ AG GP+++E TYR HS SD YR+ +E ++ DP+ F++ +L
Sbjct: 242 HARAGHGPVLIEAMTYRRGPHSTSDDPGRYRSLNEERD-DAGEDPLERFRKTLL 294
>UniRef50_Q8U4T5 Cluster: 2-oxo acid dehydrogenase subunit E1; n=1;
Haloferax volcanii|Rep: 2-oxo acid dehydrogenase subunit
E1 - Halobacterium volcanii (Haloferax volcanii)
Length = 353
Score = 38.7 bits (86), Expect = 0.11
Identities = 22/79 (27%), Positives = 39/79 (49%)
Frame = +1
Query: 19 GKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQL 198
G GP ++E++ +R GH M D +YR ++ +Q RD I + +H VT D +
Sbjct: 235 GNGPTLIEVQVHRRMGHFMGD-AEAYRPEADIDRAKQ-RDSIERLAADLRSHG-VTDDDI 291
Query: 199 KDIDAKVRKEVDEATKQSK 255
++ + V+ A +K
Sbjct: 292 DEMRERAHGRVEAAISWAK 310
>UniRef50_A4SAP2 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
Predicted protein - Ostreococcus lucimarinus CCE9901
Length = 576
Score = 38.3 bits (85), Expect = 0.14
Identities = 26/80 (32%), Positives = 40/80 (50%), Gaps = 1/80 (1%)
Frame = +1
Query: 106 DEVQEVRQTRDPIT-SFKEKILNHELVTPDQLKDIDAKVRKEVDEATKQSKRNQKSVLKS 282
D+V+E+RQ D + K+K+ T D L +I+ R E+ + K SKR + V K
Sbjct: 361 DKVEELRQRFDEVDREIKDKLQQRSGSTQDALANINR--RNEIQNSEKLSKRASEQVAKL 418
Query: 283 XXPIYTTRTWNPSSVASTRL 342
+ T + +P S TRL
Sbjct: 419 KAGVLNTGSGDPFSRRPTRL 438
>UniRef50_Q9HNV6 Cluster: Pyruvate dehydrogenase alpha subunit; n=1;
Halobacterium salinarum|Rep: Pyruvate dehydrogenase
alpha subunit - Halobacterium salinarium (Halobacterium
halobium)
Length = 322
Score = 38.3 bits (85), Expect = 0.14
Identities = 21/95 (22%), Positives = 45/95 (47%), Gaps = 1/95 (1%)
Frame = +1
Query: 28 PLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQLKDI 207
P+++E TYR H+ SD YR +E +T DP+ + + + + ++ +++
Sbjct: 204 PILVESLTYRQGAHTTSDDPDRYRPEEEDLPAWRTADPVDRYADYLHDQGVIDAGFVEEC 263
Query: 208 DAKVRKEVDEATKQSK-RNQKSVLKSXXPIYTTRT 309
E+D+A + ++ +V + +Y RT
Sbjct: 264 FDAAADEIDDAVETAEAAGAPAVDELFDHVYAERT 298
>UniRef50_Q1IY28 Cluster: Pyruvate dehydrogenase; n=1; Deinococcus
geothermalis DSM 11300|Rep: Pyruvate dehydrogenase -
Deinococcus geothermalis (strain DSM 11300)
Length = 361
Score = 37.5 bits (83), Expect = 0.24
Identities = 20/80 (25%), Positives = 40/80 (50%)
Frame = +1
Query: 19 GKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQL 198
G+GP ++E TYR H+++D + YR+ D +DP+ + +L +T +
Sbjct: 249 GEGPTLIETVTYRVKPHTVADDPSRYRS-DADTAGWDAKDPVRRLQTHLLTEGHLTEKED 307
Query: 199 KDIDAKVRKEVDEATKQSKR 258
+I ++ E + A + + R
Sbjct: 308 AEITREIEAEFEAALQVADR 327
>UniRef50_A6UDY5 Cluster: Dehydrogenase E1 component; n=2;
Alphaproteobacteria|Rep: Dehydrogenase E1 component -
Sinorhizobium medicae WSM419
Length = 342
Score = 37.5 bits (83), Expect = 0.24
Identities = 28/110 (25%), Positives = 51/110 (46%), Gaps = 1/110 (0%)
Frame = +1
Query: 1 IEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHEL 180
++ AGK P + +E YR+ GH+ D + YR E E R+ +DP+ + K+++ +
Sbjct: 223 VDEARAGK-PGFLSVEVYRFFGHARMDK-SPYREEAEELEGRK-KDPVLFARNKLIDTGI 279
Query: 181 VTPDQLKDIDAKVRKEVDEATKQSKRNQKSVLKS-XXPIYTTRTWNPSSV 327
L ++D + E+D + ++ L S +Y P SV
Sbjct: 280 EEERILDELDKAIAAEMDATIDFAVESKAPPLGSMFKDVYAAGEPEPESV 329
>UniRef50_Q6L1L8 Cluster: Pyruvate dehydrogenase E1 component alpha
subunit; n=2; Thermoplasmatales|Rep: Pyruvate
dehydrogenase E1 component alpha subunit - Picrophilus
torridus
Length = 333
Score = 37.5 bits (83), Expect = 0.24
Identities = 30/102 (29%), Positives = 49/102 (48%), Gaps = 5/102 (4%)
Frame = +1
Query: 22 KGPLVMEMETYRYSGHSMSDPGTSYRTR-----DEVQEVRQTRDPITSFKEKILNHELVT 186
K PL+++ TYR H+ +D YR D + + D I K KILN E ++
Sbjct: 228 KMPLLIDAVTYRMGPHTTADDPNKYRKTIINEGDPLDPLSIIEDDIK--KMKILNDEEIS 285
Query: 187 PDQLKDIDAKVRKEVDEATKQSKRNQKSVLKSXXPIYTTRTW 312
+ +I+ V KEV+ K +K ++++ K+ IY W
Sbjct: 286 -NIKNEINNMVSKEVERYEKMNKPGKETLFKN---IYENEPW 323
>UniRef50_A0HHH5 Cluster: Dehydrogenase, E1 component; n=2;
Bacteria|Rep: Dehydrogenase, E1 component - Comamonas
testosteroni KF-1
Length = 327
Score = 36.7 bits (81), Expect = 0.43
Identities = 23/78 (29%), Positives = 41/78 (52%)
Frame = +1
Query: 19 GKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQL 198
G GP+++EM T R GH + D SYRT E+ E + +PI ++ L V+ ++
Sbjct: 235 GHGPVLIEMMTQRLVGHYIGDM-QSYRTAREIAEAK-LHEPIVRLGQR-LQLSGVSDAEV 291
Query: 199 KDIDAKVRKEVDEATKQS 252
++I ++ AT ++
Sbjct: 292 QNIHLNAAAHIEAATAKA 309
>UniRef50_Q4N1L6 Cluster: Branched-chain alpha keto-acid
dehydrogenase, putative; n=3; Piroplasmida|Rep:
Branched-chain alpha keto-acid dehydrogenase, putative -
Theileria parva
Length = 464
Score = 36.7 bits (81), Expect = 0.43
Identities = 16/38 (42%), Positives = 21/38 (55%)
Frame = +1
Query: 4 EYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQ 117
EYC P+V+E TYR HS SD + YR + E +
Sbjct: 329 EYCVKHSTPIVIEYMTYRIGHHSTSDESSQYRGKGEFE 366
>UniRef50_Q2H9L8 Cluster: Putative uncharacterized protein; n=2;
Sordariomycetes|Rep: Putative uncharacterized protein -
Chaetomium globosum (Soil fungus)
Length = 472
Score = 36.7 bits (81), Expect = 0.43
Identities = 25/73 (34%), Positives = 41/73 (56%), Gaps = 2/73 (2%)
Frame = +1
Query: 70 SMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTP-DQLKDIDAKVRKEVDEA-T 243
S+ P T R R+ +Q R++ +P++S + NH L +P D++ D+D V +EA
Sbjct: 188 SLESPHTPLRRRN-IQPTRRSMEPVSSPPGEPENHPLSSPEDEIADLDLSVFSGKEEAPD 246
Query: 244 KQSKRNQKSVLKS 282
K++ R S LKS
Sbjct: 247 KKTSRLPFSPLKS 259
>UniRef50_Q93N50 Cluster: Pyruvate dehydrogenase alpha subunit; n=4;
Proteobacteria|Rep: Pyruvate dehydrogenase alpha subunit
- Coxiella burnetii
Length = 341
Score = 36.3 bits (80), Expect = 0.56
Identities = 20/76 (26%), Positives = 41/76 (53%), Gaps = 1/76 (1%)
Frame = +1
Query: 16 AGKGPLVMEMETYRYSGHSMSDPGT-SYRTRDEVQEVRQTRDPITSFKEKILNHELVTPD 192
A G +E +TYR+ H + T + R++ E RDP++ + ++L + V+P+
Sbjct: 226 ANGGVWFLEFQTYRFKVHCGPEEETFTDRSKTEFDHWL-ARDPLSLLQSQLLTAKTVSPE 284
Query: 193 QLKDIDAKVRKEVDEA 240
++ +++ E+DEA
Sbjct: 285 EIDKWRHEIQNEIDEA 300
>UniRef50_Q8PQ82 Cluster: Pyruvate dehydrogenase E1 alpha subunit;
n=7; Xanthomonadaceae|Rep: Pyruvate dehydrogenase E1
alpha subunit - Xanthomonas axonopodis pv. citri
Length = 362
Score = 36.3 bits (80), Expect = 0.56
Identities = 25/77 (32%), Positives = 39/77 (50%), Gaps = 4/77 (5%)
Frame = +1
Query: 16 AGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHEL---VT 186
AG+G V+E TYR S H+ +D YR +EV++ R+P+ + + L
Sbjct: 247 AGEGGTVIEFLTYRLSDHTTADDARRYRGEEEVKQ-GWAREPLLRLRRYLTAQGLWDEAQ 305
Query: 187 PDQLK-DIDAKVRKEVD 234
D K D A+V +EV+
Sbjct: 306 EDAWKADCSARVDEEVN 322
>UniRef50_Q8D6Q7 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex, dehydrogenase component, eukaryotic type, alpha
subunit; n=4; Vibrionaceae|Rep: Pyruvate/2-oxoglutarate
dehydrogenase complex, dehydrogenase component,
eukaryotic type, alpha subunit - Vibrio vulnificus
Length = 364
Score = 36.3 bits (80), Expect = 0.56
Identities = 20/80 (25%), Positives = 42/80 (52%)
Frame = +1
Query: 1 IEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHEL 180
++ GKG ++E +YR S H+ +D + YR+ DE+++ Q +PI + + L
Sbjct: 239 LDRARKGKGATLIEAISYRLSDHTTADDASRYRSADELKQAWQ-YEPIKRLQAYLTAQGL 297
Query: 181 VTPDQLKDIDAKVRKEVDEA 240
+ + A +++V++A
Sbjct: 298 WNEELEQQWLAHCKQQVEQA 317
>UniRef50_A5V557 Cluster: Pyruvate dehydrogenase; n=1; Sphingomonas
wittichii RW1|Rep: Pyruvate dehydrogenase - Sphingomonas
wittichii RW1
Length = 331
Score = 36.3 bits (80), Expect = 0.56
Identities = 23/74 (31%), Positives = 39/74 (52%)
Frame = +1
Query: 19 GKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQL 198
G GP ++E +TYRY+ H+++ EV E R+ RDP+ ++ K++ L
Sbjct: 228 GGGPTLVETKTYRYADHAVNMGRVLLDRGGEVDEWRK-RDPLALYRAKLIAGGTAAA-LL 285
Query: 199 KDIDAKVRKEVDEA 240
I+ +V EV +A
Sbjct: 286 DAIEREVADEVADA 299
>UniRef50_A0JUQ5 Cluster: Pyruvate dehydrogenase; n=4;
Actinobacteria (class)|Rep: Pyruvate dehydrogenase -
Arthrobacter sp. (strain FB24)
Length = 392
Score = 36.3 bits (80), Expect = 0.56
Identities = 21/67 (31%), Positives = 35/67 (52%)
Frame = +1
Query: 1 IEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHEL 180
+E G GP +E TYR H+ +D T YR +E+++ +DPI + + L
Sbjct: 260 LERARHGGGPTFIEAVTYRMGPHTTADDPTRYRDANELED-WAAKDPIARVRGLLERKGL 318
Query: 181 VTPDQLK 201
+T D+L+
Sbjct: 319 LT-DELE 324
>UniRef50_P09060 Cluster: 2-oxoisovalerate dehydrogenase subunit
alpha; n=68; Proteobacteria|Rep: 2-oxoisovalerate
dehydrogenase subunit alpha - Pseudomonas putida
Length = 410
Score = 36.3 bits (80), Expect = 0.56
Identities = 23/85 (27%), Positives = 39/85 (45%)
Frame = +1
Query: 4 EYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELV 183
E G GP ++E TYR HS SD + YR D+ DPI K+ ++
Sbjct: 291 ERARRGLGPSLIEWVTYRAGPHSTSDDPSKYRPADDWSHF-PLGDPIARLKQHLIKIGHW 349
Query: 184 TPDQLKDIDAKVRKEVDEATKQSKR 258
+ ++ + A+ V A K++++
Sbjct: 350 SEEEHQATTAEFEAAVIAAQKEAEQ 374
>UniRef50_Q28MR4 Cluster: Dehydrogenase E1 component; n=8;
Bacteria|Rep: Dehydrogenase E1 component - Jannaschia
sp. (strain CCS1)
Length = 675
Score = 35.9 bits (79), Expect = 0.74
Identities = 18/43 (41%), Positives = 27/43 (62%)
Frame = +1
Query: 16 AGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPI 144
AG GP ++E TYR+ HSM +YR+ E +E +++DPI
Sbjct: 241 AGDGPTLIEALTYRWDDHSMRANLPAYRSEAE-EEAWKSQDPI 282
>UniRef50_Q0RLC2 Cluster: Pyruvate dehydrogenase E1 component, alpha
subunit; n=2; Bacteria|Rep: Pyruvate dehydrogenase E1
component, alpha subunit - Frankia alni (strain ACN14a)
Length = 342
Score = 35.9 bits (79), Expect = 0.74
Identities = 23/80 (28%), Positives = 38/80 (47%)
Frame = +1
Query: 1 IEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHEL 180
IE G GP ++E T+R+ GH M D Y +E++ DP+ F+ ++
Sbjct: 237 IERARTGGGPTLLEAMTFRFCGHIMGDQQV-YMPPEELR-AAIAADPLVRFRAQLAAD-- 292
Query: 181 VTPDQLKDIDAKVRKEVDEA 240
V D+L ++ EV +A
Sbjct: 293 VGEDELAAVERAAADEVADA 312
>UniRef50_A7PGG3 Cluster: Chromosome chr17 scaffold_16, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr17 scaffold_16, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 300
Score = 35.9 bits (79), Expect = 0.74
Identities = 18/43 (41%), Positives = 26/43 (60%)
Frame = +1
Query: 22 KGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITS 150
K LV MET SG+ SDPG S R ++Q+ R+ ++P +S
Sbjct: 41 KHDLVNPMETECNSGYGFSDPGVSPRVTADLQQNRENKNPNSS 83
>UniRef50_A0DAM1 Cluster: Chromosome undetermined scaffold_43, whole
genome shotgun sequence; n=3; Oligohymenophorea|Rep:
Chromosome undetermined scaffold_43, whole genome
shotgun sequence - Paramecium tetraurelia
Length = 406
Score = 35.9 bits (79), Expect = 0.74
Identities = 24/83 (28%), Positives = 32/83 (38%), Gaps = 2/83 (2%)
Frame = +1
Query: 22 KGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHEL--VTPDQ 195
K P +E TYR HS SD YR+++E+ + +PI + L D
Sbjct: 278 KEPFFIEFITYRIGDHSTSDHSVLYRSQEEIDSWKSGNNPINRLGLFLKKQGLRQFNDDH 337
Query: 196 LKDIDAKVRKEVDEATKQSKRNQ 264
I VR V A K Q
Sbjct: 338 DNQIRKDVRNRVIAALKHGSEQQ 360
>UniRef50_Q9Z9E8 Cluster: (Pyruvate) Oxoisovalerate Dehydrogenase
Alpha/Beta Fusion ((Pyruvate) oxoisovalerate
dehydrogenase alpha and beta fusion); n=7;
Chlamydiaceae|Rep: (Pyruvate) Oxoisovalerate
Dehydrogenase Alpha/Beta Fusion ((Pyruvate)
oxoisovalerate dehydrogenase alpha and beta fusion) -
Chlamydia pneumoniae (Chlamydophila pneumoniae)
Length = 678
Score = 34.7 bits (76), Expect = 1.7
Identities = 17/68 (25%), Positives = 41/68 (60%)
Frame = +1
Query: 28 PLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQLKDI 207
P ++ ++ R S HS SD YR+ ++ ++ +DP+ +++ +N ++P ++++I
Sbjct: 237 PALILIDVVRLSSHSNSDNQEKYRSALDL-KLSMDKDPLILLEKEAINVFGLSPFEIEEI 295
Query: 208 DAKVRKEV 231
A+ ++EV
Sbjct: 296 KAEAQEEV 303
>UniRef50_Q7QY55 Cluster: GLP_572_50389_48461; n=2; Giardia
intestinalis|Rep: GLP_572_50389_48461 - Giardia lamblia
ATCC 50803
Length = 642
Score = 34.7 bits (76), Expect = 1.7
Identities = 28/97 (28%), Positives = 49/97 (50%), Gaps = 8/97 (8%)
Frame = +1
Query: 1 IEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKIL---- 168
++ NAG G V + E Y G+ M T Y T DE+ V+ R + K+K +
Sbjct: 377 MQQANAGSGSEVEDKEAYDGEGN-MGAGFTGY-TADEMANVQSLRKNLDKTKKKRVKYVE 434
Query: 169 ----NHELVTPDQLKDIDAKVRKEVDEATKQSKRNQK 267
N E V+ ++L ++ + +K+++E K+S+R K
Sbjct: 435 QRKENEEAVSAEELATLEEE-QKKLEEQIKESERKAK 470
>UniRef50_Q1KSF2 Cluster: Mitochondrial branched-chain alpha-keto
acid dehydrogenase E1; n=1; Toxoplasma gondii|Rep:
Mitochondrial branched-chain alpha-keto acid
dehydrogenase E1 - Toxoplasma gondii
Length = 463
Score = 34.7 bits (76), Expect = 1.7
Identities = 24/99 (24%), Positives = 44/99 (44%), Gaps = 3/99 (3%)
Frame = +1
Query: 28 PLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTR-DPITSFKEKILNHELVTPDQLKD 204
P+++E TYR HS SD YR E++ Q+ PI + + N L + Q ++
Sbjct: 337 PVLIEFMTYRVGHHSTSDDSFQYRPSGELEAWGQSGIHPIARVRRYLDNLNLWSDKQDEE 396
Query: 205 IDAKVRKEVDEATKQSKRNQKSVLKS--XXPIYTTRTWN 315
+ R + K +++++S + +Y WN
Sbjct: 397 LRKDARATMLRMMKVVEKDKRSAVIGGIFDDVYDKEPWN 435
>UniRef50_Q0MX87 Cluster: Acetoin dehydrogenase alpha-subunit; n=2;
Bacteria|Rep: Acetoin dehydrogenase alpha-subunit -
consortium cosmid clone pGZ1
Length = 344
Score = 34.3 bits (75), Expect = 2.3
Identities = 23/75 (30%), Positives = 38/75 (50%)
Frame = +1
Query: 16 AGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQ 195
AG+GP ++ +TYR++GH DP +YR E+ + DP+ + + L V D
Sbjct: 244 AGEGPRLLHAKTYRFTGHVSVDP-AAYRDPGELAAAMED-DPLLVARVR-LQASGVAGDA 300
Query: 196 LKDIDAKVRKEVDEA 240
++ R+EV A
Sbjct: 301 VEAAMRAAREEVAAA 315
>UniRef50_Q9FNY4 Cluster: DNA polymerase lambda; n=31;
Spermatophyta|Rep: DNA polymerase lambda - Arabidopsis
thaliana (Mouse-ear cress)
Length = 529
Score = 34.3 bits (75), Expect = 2.3
Identities = 20/75 (26%), Positives = 36/75 (48%), Gaps = 1/75 (1%)
Frame = -2
Query: 258 PFRLFSGLVYFFTYLGVDILEL-IWRDELVIQDLLLERSDGVSGLPHLLHLVSRPIRRAG 82
P +F+G+V F +GV L IW+ +LV ++E + H+L + +
Sbjct: 15 PEGMFAGMVVFMVEIGVQRRRLQIWKQKLVQMGAVIEEDRVTKKVTHVLAMNLEALLHKF 74
Query: 81 VRHRMTRVTVRLHLH 37
+ R++ T RL L+
Sbjct: 75 GKERLSHFTARLMLY 89
>UniRef50_A5KBH9 Cluster: Putative uncharacterized protein; n=1;
Plasmodium vivax|Rep: Putative uncharacterized protein -
Plasmodium vivax
Length = 1860
Score = 34.3 bits (75), Expect = 2.3
Identities = 15/55 (27%), Positives = 34/55 (61%)
Frame = +1
Query: 115 QEVRQTRDPITSFKEKILNHELVTPDQLKDIDAKVRKEVDEATKQSKRNQKSVLK 279
+++++T ITS KI+N+E D K++ + K+VD+A ++ + +++ +K
Sbjct: 87 EQLKETLRSITSLSTKIVNYETKIEDLEKELKMEKDKQVDKAYEKELKEKENFIK 141
>UniRef50_UPI00004993C7 Cluster: hypothetical protein 3.t00030; n=1;
Entamoeba histolytica HM-1:IMSS|Rep: hypothetical
protein 3.t00030 - Entamoeba histolytica HM-1:IMSS
Length = 1144
Score = 33.9 bits (74), Expect = 3.0
Identities = 19/58 (32%), Positives = 28/58 (48%)
Frame = +1
Query: 109 EVQEVRQTRDPITSFKEKILNHELVTPDQLKDIDAKVRKEVDEATKQSKRNQKSVLKS 282
E + + ++ I FKEK+ E ID V+KE E KQ+ N K ++KS
Sbjct: 603 ETERQERKKEEIEEFKEKVYETEKKIEGITNRIDEMVKKEEIEEIKQNIDNIKEIIKS 660
>UniRef50_Q83DQ6 Cluster: Dehydrogenase, E1 component, alpha
subunit; n=3; Coxiella burnetii|Rep: Dehydrogenase, E1
component, alpha subunit - Coxiella burnetii
Length = 368
Score = 33.9 bits (74), Expect = 3.0
Identities = 19/83 (22%), Positives = 42/83 (50%)
Frame = +1
Query: 1 IEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHEL 180
+E G GP ++E +YR H+ +D T Y ++E +V ++PI + + L
Sbjct: 243 LEKARDGGGPTLIEALSYRLCDHTTADDATRYIPQEE-WKVAWQKEPIARLGYYLESQGL 301
Query: 181 VTPDQLKDIDAKVRKEVDEATKQ 249
+ ++ + ++ +EVD+ ++
Sbjct: 302 WSREKEAVLQKELAQEVDQVVEE 324
>UniRef50_Q1LFS5 Cluster: Dehydrogenase, E1 component; n=22;
Proteobacteria|Rep: Dehydrogenase, E1 component -
Ralstonia metallidurans (strain CH34 / ATCC 43123 / DSM
2839)
Length = 367
Score = 33.9 bits (74), Expect = 3.0
Identities = 16/53 (30%), Positives = 28/53 (52%)
Frame = +1
Query: 1 IEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKE 159
IE+ G GP ++E +YR H+ +D + YR V+E + +PI ++
Sbjct: 238 IEHARHGGGPTLIEAVSYRLGDHTTADDASRYRDEASVKEAWRC-EPIIRLRD 289
>UniRef50_A3PXW7 Cluster: Transketolase domain protein; n=4;
Mycobacterium|Rep: Transketolase domain protein -
Mycobacterium sp. (strain JLS)
Length = 721
Score = 33.9 bits (74), Expect = 3.0
Identities = 21/82 (25%), Positives = 40/82 (48%), Gaps = 1/82 (1%)
Frame = +1
Query: 4 EYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELV 183
E+ + P + + T R GH+ SD YR DE+ RDP+ + ++ ++
Sbjct: 265 EFVRTHRRPAFLHLSTVRLMGHAGSDYEPGYRRPDEI-VADFDRDPVLCAAKALVAQGIL 323
Query: 184 TP-DQLKDIDAKVRKEVDEATK 246
+P + L+ +A R+ +D A +
Sbjct: 324 SPVEVLERYEATRRQVLDMAAE 345
>UniRef50_Q7Q6F7 Cluster: ENSANGP00000004512; n=2; Diptera|Rep:
ENSANGP00000004512 - Anopheles gambiae str. PEST
Length = 1179
Score = 33.9 bits (74), Expect = 3.0
Identities = 16/60 (26%), Positives = 33/60 (55%)
Frame = +1
Query: 88 TSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQLKDIDAKVRKEVDEATKQSKRNQK 267
T+Y+ + Q +RQTR+ FK++++N + + KD+ KV + + + Q++ K
Sbjct: 1117 TNYKAKQSKQ-LRQTRERSKKFKKELVNEKFKKLQRQKDLKKKVFRAISKMDTQNEEKMK 1175
>UniRef50_Q3SE24 Cluster: KdG6; n=9; Paramecium tetraurelia|Rep:
KdG6 - Paramecium tetraurelia
Length = 248
Score = 33.9 bits (74), Expect = 3.0
Identities = 19/67 (28%), Positives = 39/67 (58%)
Frame = +1
Query: 76 SDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQLKDIDAKVRKEVDEATKQSK 255
+D GT R+ +E+ R+ + +T+ K+ E + LKD+ ++V+ E++E K +
Sbjct: 169 NDNGTLRRSGEEI---RRLNEGLTNQKKLREESETAIFEMLKDLVSRVKSEIEEEKKLRE 225
Query: 256 RNQKSVL 276
+Q+S+L
Sbjct: 226 ESQESLL 232
>UniRef50_A7RZV6 Cluster: Predicted protein; n=6; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 444
Score = 33.9 bits (74), Expect = 3.0
Identities = 22/84 (26%), Positives = 40/84 (47%)
Frame = +1
Query: 28 PLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQLKDI 207
P+++E TYR HS SD + YR+ EV + PI+ + + + DQ +
Sbjct: 321 PVLVEAMTYRIGHHSTSDDSSVYRSLKEVNYWDKEDHPISRLRYYMEDKGWWDQDQEQQW 380
Query: 208 DAKVRKEVDEATKQSKRNQKSVLK 279
+ R +V +A +++ K +K
Sbjct: 381 KKEARLQVMQAFADAEKALKPPVK 404
>UniRef50_UPI0000F2B7FC Cluster: PREDICTED: similar to F-box protein
16,; n=1; Monodelphis domestica|Rep: PREDICTED: similar
to F-box protein 16, - Monodelphis domestica
Length = 501
Score = 33.5 bits (73), Expect = 4.0
Identities = 16/43 (37%), Positives = 23/43 (53%)
Frame = -1
Query: 142 WGLWSASPPAPRLSSDTTCRGPTSNDQSNGTSPSPSPKDLSLR 14
+G+W+ SPPA L T S+ N T+P P+P+ S R
Sbjct: 394 FGVWTRSPPASSLIFKTRDSPSPSSRVRNATTPYPTPEPRSFR 436
>UniRef50_Q5LVW0 Cluster: Dehydrogenase/transketolase family
protein; n=23; Proteobacteria|Rep:
Dehydrogenase/transketolase family protein -
Silicibacter pomeroyi
Length = 740
Score = 33.5 bits (73), Expect = 4.0
Identities = 16/47 (34%), Positives = 26/47 (55%)
Frame = +1
Query: 4 EYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPI 144
+Y + P + ++T R GH+ +D T+Y TR EV E + DP+
Sbjct: 274 DYVRNRRKPAFLHLKTVRLYGHAGADVPTTYLTRAEV-EAEEAMDPL 319
>UniRef50_UPI0000E4A126 Cluster: PREDICTED: similar to Im:7141452
protein; n=2; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to Im:7141452 protein -
Strongylocentrotus purpuratus
Length = 646
Score = 33.1 bits (72), Expect = 5.2
Identities = 26/119 (21%), Positives = 56/119 (47%), Gaps = 4/119 (3%)
Frame = +1
Query: 31 LVMEMETYRYSGHSMSDPGTSYRT--RDEVQEVRQTRDPITSFKEKILNHELVTPDQ-LK 201
LV +M++ + H + ++ + + + +R+ RD I + +I + + + D+ LK
Sbjct: 248 LVRQMKSQKMLRHVFEEENSNLKQDLQGANEIIRELRDKIEKLEMEIQDLKKASEDKSLK 307
Query: 202 DIDAKVRKEVDEATKQSKRNQKSVLKSXXPIYTTRTWNPSSVASTRLPRS-NTLRSNLA 375
D D RKE + ++ K++++ + P + + S A L + TL+ LA
Sbjct: 308 DFDYVTRKEAADVKQEEKKHEQMTSSAQTPAQASSSEGVSVEAYESLQKKIITLKQKLA 366
>UniRef50_Q2S3D2 Cluster: 2-oxoglutarate dehydrogenase, E1
component; n=3; Bacteria|Rep: 2-oxoglutarate
dehydrogenase, E1 component - Salinibacter ruber (strain
DSM 13855)
Length = 1243
Score = 33.1 bits (72), Expect = 5.2
Identities = 20/84 (23%), Positives = 39/84 (46%)
Frame = +1
Query: 4 EYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELV 183
EY +V++M YR GH+ D T + +++ + R P + E +L +
Sbjct: 744 EYRQRFNKDVVIDMMCYRVHGHNEGDEPT-FTQPLLYEKIEEKRSPRKLYTEMLLRRGEI 802
Query: 184 TPDQLKDIDAKVRKEVDEATKQSK 255
PD+ + + R + EA +++K
Sbjct: 803 EPDEAEQMLDDYRGRLQEAFERTK 826
>UniRef50_Q83X26 Cluster: Probable pyruvate dehydrogenase
alpha-subunit; n=1; Streptomyces rochei|Rep: Probable
pyruvate dehydrogenase alpha-subunit - Streptomyces
rochei (Streptomyces parvullus)
Length = 326
Score = 32.7 bits (71), Expect = 6.9
Identities = 10/23 (43%), Positives = 17/23 (73%)
Frame = +1
Query: 1 IEYCNAGKGPLVMEMETYRYSGH 69
+E+C +G GP +E++TYR+ H
Sbjct: 218 VEHCRSGTGPYFLELDTYRWREH 240
>UniRef50_Q023C4 Cluster: Pyruvate dehydrogenase; n=1; Solibacter
usitatus Ellin6076|Rep: Pyruvate dehydrogenase -
Solibacter usitatus (strain Ellin6076)
Length = 397
Score = 32.7 bits (71), Expect = 6.9
Identities = 18/64 (28%), Positives = 36/64 (56%), Gaps = 1/64 (1%)
Frame = +1
Query: 154 KEKILNHELVTPDQLKDIDAKVRKEVDEATKQSKRN-QKSVLKSXXPIYTTRTWNPSSVA 330
K+ ++ + ++TPD+++ A ++ EVD+A ++ + Q + IY+ RT P+ V
Sbjct: 6 KDTLIRNRVLTPDEVEAFRASIKSEVDQAAAEADSHPQPATSNLLAHIYSERT-APAIVR 64
Query: 331 STRL 342
T L
Sbjct: 65 PTYL 68
>UniRef50_A6Q7R1 Cluster: Putative uncharacterized protein; n=1;
Sulfurovum sp. NBC37-1|Rep: Putative uncharacterized
protein - Sulfurovum sp. (strain NBC37-1)
Length = 383
Score = 32.7 bits (71), Expect = 6.9
Identities = 18/66 (27%), Positives = 33/66 (50%), Gaps = 1/66 (1%)
Frame = +1
Query: 88 TSYRTRDEVQEVRQ-TRDPITSFKEKILNHELVTPDQLKDIDAKVRKEVDEATKQSKRNQ 264
TS RD EV + T+D IT+ + + + + KD V K++++ATK +
Sbjct: 89 TSKDVRDATVEVAEDTKDSITNTTKDLKDSTTIASKDFKDSAISVSKDINDATKTVSNDS 148
Query: 265 KSVLKS 282
+ +K+
Sbjct: 149 RDSVKT 154
>UniRef50_A6LT96 Cluster: Transposase IS3/IS911 family protein; n=1;
Clostridium beijerinckii NCIMB 8052|Rep: Transposase
IS3/IS911 family protein - Clostridium beijerinckii
NCIMB 8052
Length = 106
Score = 32.7 bits (71), Expect = 6.9
Identities = 13/38 (34%), Positives = 26/38 (68%)
Frame = +1
Query: 154 KEKILNHELVTPDQLKDIDAKVRKEVDEATKQSKRNQK 267
KEKI ++T +++++ + K +K+V+E +K K N+K
Sbjct: 48 KEKISKKPIITNNKIRNNEIKDKKDVEEISKLKKENEK 85
>UniRef50_Q8ILU2 Cluster: Putative uncharacterized protein; n=2;
Plasmodium|Rep: Putative uncharacterized protein -
Plasmodium falciparum (isolate 3D7)
Length = 1474
Score = 32.7 bits (71), Expect = 6.9
Identities = 11/25 (44%), Positives = 14/25 (56%)
Frame = -2
Query: 528 LCCRYKKNNFYQRYCHINATVKKNN 454
+CC Y NN Y YC+ N + NN
Sbjct: 1307 VCCNYLNNNVYNNYCYDNNFMDNNN 1331
>UniRef50_Q5CW69 Cluster: PP2C like protein phosphatase; n=2;
Cryptosporidium|Rep: PP2C like protein phosphatase -
Cryptosporidium parvum Iowa II
Length = 752
Score = 32.7 bits (71), Expect = 6.9
Identities = 18/59 (30%), Positives = 38/59 (64%)
Frame = +1
Query: 103 RDEVQEVRQTRDPITSFKEKILNHELVTPDQLKDIDAKVRKEVDEATKQSKRNQKSVLK 279
R+ + +R+TRD + + K +I+ + + Q KDI+ K RK+++ + +++ +KS+LK
Sbjct: 55 RNRQRLIRETRDQLLNLKTRIICEDEIEEIQRKDIE-KSRKKMN-VEEGNRKIKKSILK 111
>UniRef50_UPI00015A6B18 Cluster: UPI00015A6B18 related cluster; n=2;
Danio rerio|Rep: UPI00015A6B18 UniRef100 entry - Danio
rerio
Length = 225
Score = 32.3 bits (70), Expect = 9.2
Identities = 14/34 (41%), Positives = 24/34 (70%)
Frame = +1
Query: 166 LNHELVTPDQLKDIDAKVRKEVDEATKQSKRNQK 267
L H+L+TP+QLK+I+A++ +E K+ KR +
Sbjct: 8 LAHDLITPEQLKNIEARL-TATEETLKELKRENE 40
>UniRef50_Q4AAN6 Cluster: Putative uncharacterized protein; n=5;
Mycoplasma hyopneumoniae|Rep: Putative uncharacterized
protein - Mycoplasma hyopneumoniae (strain J / ATCC
25934 / NCTC 10110)
Length = 521
Score = 32.3 bits (70), Expect = 9.2
Identities = 22/84 (26%), Positives = 38/84 (45%), Gaps = 6/84 (7%)
Frame = +1
Query: 34 VMEMETYRYSGHSMSDPGTSYRTRDEVQEV--RQTRDPIT----SFKEKILNHELVTPDQ 195
+++ T Y +PG + E+Q ++T++ I SFK +I N D+
Sbjct: 13 LVDSGTLTYKLLEAGNPGDWFSLVSEIQNYIEQKTKEKIKQKLESFKSQIRNDIFTNDDE 72
Query: 196 LKDIDAKVRKEVDEATKQSKRNQK 267
+K + +RK DE + NQK
Sbjct: 73 IKQMKETIRKLSDENSSLKSENQK 96
>UniRef50_Q2SHW5 Cluster: Putative uncharacterized protein; n=1;
Hahella chejuensis KCTC 2396|Rep: Putative
uncharacterized protein - Hahella chejuensis (strain
KCTC 2396)
Length = 196
Score = 32.3 bits (70), Expect = 9.2
Identities = 20/80 (25%), Positives = 37/80 (46%)
Frame = +1
Query: 37 MEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQLKDIDAK 216
+E++TY G +M+ PG+ T D Q + + I+N E+ T + ++D+ +
Sbjct: 37 LEVKTYTKDGLTMTIPGSWRATEDSYQTWGTRFLSFDAVDDAIVNVEIYTAENVRDLKKE 96
Query: 217 VRKEVDEATKQSKRNQKSVL 276
+ + KQ R S L
Sbjct: 97 DNFGLQKLVKQYNRLSDSFL 116
>UniRef50_A1GCL6 Cluster: Transketolase-like; n=2; Salinispora|Rep:
Transketolase-like - Salinispora arenicola CNS205
Length = 805
Score = 32.3 bits (70), Expect = 9.2
Identities = 15/48 (31%), Positives = 25/48 (52%)
Frame = +1
Query: 1 IEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPI 144
+ + + P V+ + T R GH+ +D T+YRT E+ RDP+
Sbjct: 325 VRWVRRHRRPAVLHLSTVRLMGHAGADAETAYRTTTEI-AADLDRDPL 371
>UniRef50_Q8I2L0 Cluster: Putative uncharacterized protein PFI1480w;
n=2; Plasmodium|Rep: Putative uncharacterized protein
PFI1480w - Plasmodium falciparum (isolate 3D7)
Length = 915
Score = 32.3 bits (70), Expect = 9.2
Identities = 17/51 (33%), Positives = 29/51 (56%), Gaps = 3/51 (5%)
Frame = -2
Query: 591 LNTTFIIYNCDVYIT*VEGNILCCRYKKNNFYQRYCH---INATVKKNNKS 448
LN ++ YN Y+ + N + +YKKN+FY+ Y +N KKN+++
Sbjct: 282 LNNNYVNYNEKKYMC--QSNNIYMKYKKNHFYKNYDDEKLLNRNFKKNSQA 330
>UniRef50_Q6UEA5 Cluster: Zinc metallopeptidase 6; n=5;
Ancylostoma|Rep: Zinc metallopeptidase 6 - Ancylostoma
ceylanicum
Length = 902
Score = 32.3 bits (70), Expect = 9.2
Identities = 24/94 (25%), Positives = 41/94 (43%), Gaps = 2/94 (2%)
Frame = +1
Query: 82 PGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQLKDIDAKVRKEVDE--ATKQSK 255
P +S V E + T+ P++ + + H VT + V K +T +++
Sbjct: 48 PQSSSVVHTTVTEPKSTK-PVSKPQSSSVVHTTVTESKSTKTTRPVTKPTTTVPSTTRTR 106
Query: 256 RNQKSVLKSXXPIYTTRTWNPSSVASTRLPRSNT 357
+ KS + + T RT PS+ STR P + T
Sbjct: 107 ISTKSTTRKSSAVTTPRTLRPSTTTSTRRPFTTT 140
>UniRef50_Q23RJ8 Cluster: Putative uncharacterized protein; n=1;
Tetrahymena thermophila SB210|Rep: Putative
uncharacterized protein - Tetrahymena thermophila SB210
Length = 1020
Score = 32.3 bits (70), Expect = 9.2
Identities = 26/113 (23%), Positives = 53/113 (46%), Gaps = 3/113 (2%)
Frame = +1
Query: 28 PLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQLKDI 207
P+ + +++ ++ +D G S+ E + R+ ++ K++ PD K++
Sbjct: 404 PISINLDSSKFINICKNDHGQSFEELTETSSMTTYRNSLSPQKDQS------KPDICKNV 457
Query: 208 DAKVRKEVDEATKQSKRNQKSVLKSXXPIYTTRTW---NPSSVASTRLPRSNT 357
D K R + +Q+ + K +LKS + +PSS+ S R P+SN+
Sbjct: 458 DNKNRSSILNNMEQNNIDSKPILKSNVVQFQNEIKPEDSPSSLFSIR-PKSNS 509
>UniRef50_Q2HHP7 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized
protein - Chaetomium globosum (Soil fungus)
Length = 277
Score = 32.3 bits (70), Expect = 9.2
Identities = 15/38 (39%), Positives = 22/38 (57%)
Frame = -1
Query: 130 SASPPAPRLSSDTTCRGPTSNDQSNGTSPSPSPKDLSL 17
S +PPA SD T PTS ++ ++PS SP+ +L
Sbjct: 172 STTPPAATTDSDQTQSAPTSPTATDTSTPSESPQSTTL 209
>UniRef50_Q0CEB2 Cluster: Predicted protein; n=2; Trichocomaceae|Rep:
Predicted protein - Aspergillus terreus (strain NIH 2624)
Length = 968
Score = 32.3 bits (70), Expect = 9.2
Identities = 20/52 (38%), Positives = 25/52 (48%)
Frame = +3
Query: 21 ERSFGDGDGDVPLLWSFDVGPRHVVSDERRGAGGEADQRPHHFVQGEDLESR 176
+RS GD + P+ FDVGPR + RG EA R QG E+R
Sbjct: 890 DRSCGDSSDEWPITEEFDVGPRICSTTASRGREVEAQGR--QMDQGRPRETR 939
>UniRef50_A6S0G6 Cluster: Predicted protein; n=1; Botryotinia
fuckeliana B05.10|Rep: Predicted protein - Botryotinia
fuckeliana B05.10
Length = 806
Score = 32.3 bits (70), Expect = 9.2
Identities = 24/68 (35%), Positives = 33/68 (48%), Gaps = 5/68 (7%)
Frame = +1
Query: 43 METYRYSGHSMSDPGTSYRTRDEVQEVRQTRD-----PITSFKEKILNHELVTPDQLKDI 207
M R + + GT TRDE + +TRD P T +K K+LN E V D L +I
Sbjct: 726 MPQVRRCSYDLYSDGTRGATRDE--PIFETRDHAEPTPFTQWKIKLLNPEEVNLDGLNEI 783
Query: 208 DAKVRKEV 231
+ + R V
Sbjct: 784 NLRWRGRV 791
>UniRef50_Q8U3N7 Cluster: Putative uncharacterized protein PF0420;
n=1; Pyrococcus furiosus|Rep: Putative uncharacterized
protein PF0420 - Pyrococcus furiosus
Length = 952
Score = 32.3 bits (70), Expect = 9.2
Identities = 17/42 (40%), Positives = 26/42 (61%)
Frame = -1
Query: 142 WGLWSASPPAPRLSSDTTCRGPTSNDQSNGTSPSPSPKDLSL 17
W ++ A+PP +S + T PT QSN T+P+P+P+ SL
Sbjct: 318 WVIFDATPP---MSLEET---PTQETQSNTTTPTPTPEKCSL 353
>UniRef50_Q13029 Cluster: PR domain zinc finger protein 2; n=16;
Amniota|Rep: PR domain zinc finger protein 2 - Homo
sapiens (Human)
Length = 1718
Score = 32.3 bits (70), Expect = 9.2
Identities = 16/37 (43%), Positives = 23/37 (62%)
Frame = -1
Query: 130 SASPPAPRLSSDTTCRGPTSNDQSNGTSPSPSPKDLS 20
+ASP P LSS ++ +S+ S+ +S SPSP LS
Sbjct: 1043 AASPGPPTLSSSSSSSSSSSSFSSSSSSSSPSPPPLS 1079
>UniRef50_Q8YJE4 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=97; Bacteria|Rep: 2-oxoglutarate dehydrogenase E1
component - Brucella melitensis
Length = 1004
Score = 32.3 bits (70), Expect = 9.2
Identities = 22/82 (26%), Positives = 42/82 (51%), Gaps = 3/82 (3%)
Frame = +1
Query: 28 PLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQLKDI 207
P+V++M YR GH+ D S+ + +R + + + EK++ LVT D + +
Sbjct: 502 PVVIDMFCYRRFGHNEGDE-PSFTQPLMYKAIRAHKTTVQLYGEKLIAEGLVTQDDIDRM 560
Query: 208 DAKVRKEVD---EATKQSKRNQ 264
A R++++ EA + K N+
Sbjct: 561 KADWRQKLEGEFEAGQSYKPNK 582
>UniRef50_A5E032 Cluster: mRNA cap guanine-N7 methyltransferase (EC
2.1.1.56) (mRNA (guanine- N(7)-)-methyltransferase);
n=2; Saccharomycetaceae|Rep: mRNA cap guanine-N7
methyltransferase (EC 2.1.1.56) (mRNA (guanine-
N(7)-)-methyltransferase) - Lodderomyces elongisporus
(Yeast) (Saccharomyces elongisporus)
Length = 572
Score = 32.3 bits (70), Expect = 9.2
Identities = 16/48 (33%), Positives = 29/48 (60%)
Frame = +1
Query: 172 HELVTPDQLKDIDAKVRKEVDEATKQSKRNQKSVLKSXXPIYTTRTWN 315
H ++ + +DI++ VR+ +E T+QSKR + ++ PIY R +N
Sbjct: 227 HSKISDRENRDINSIVRQHYNERTQQSKRQGR---RTMSPIYKLRNFN 271
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 581,897,732
Number of Sequences: 1657284
Number of extensions: 12010938
Number of successful extensions: 46773
Number of sequences better than 10.0: 180
Number of HSP's better than 10.0 without gapping: 43635
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 46615
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 43147568152
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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