Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= br--1006
(762 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X06745-1|CAA29920.1| 1462|Homo sapiens protein ( Human mRNA for ... 104 4e-22
AY275833-1|AAP13534.1| 1462|Homo sapiens polymerase (DNA directe... 104 4e-22
M81735-1|AAA35768.1| 1107|Homo sapiens DNA polymerase delta prot... 48 5e-05
M80397-1|AAA58439.1| 1107|Homo sapiens DNA polymerase-delta cata... 48 5e-05
DQ234348-1|ABB29977.1| 1133|Homo sapiens DNA-directed polymerase... 48 5e-05
BC008800-1|AAH08800.1| 1107|Homo sapiens polymerase (DNA directe... 48 5e-05
AY129569-1|AAM76971.1| 1107|Homo sapiens polymerase (DNA directe... 48 5e-05
AB209560-1|BAD92797.1| 1011|Homo sapiens polymerase (DNA directe... 46 2e-04
>X06745-1|CAA29920.1| 1462|Homo sapiens protein ( Human mRNA for DNA
polymerase alpha-subunit. ).
Length = 1462
Score = 104 bits (249), Expect = 4e-22
Identities = 43/84 (51%), Positives = 64/84 (76%)
Frame = +2
Query: 254 VNSKNSRRFKKGDIVPYIICEDGTANSATQRAYHIEELKNSEHLKVDFKYYLAHQLHPVI 433
+NS+ R+ K GD V Y+IC+DG+ +A+QRAY E+L+ ++L +D +YYLA Q+HPV+
Sbjct: 1161 INSQGGRKVKAGDTVSYVICQDGSNLTASQRAYAPEQLQKQDNLTIDTQYYLAQQIHPVV 1220
Query: 434 SRICEPIEGMDPARVADCLGLDPS 505
+RICEPI+G+D +A LGLDP+
Sbjct: 1221 ARICEPIDGIDAVLIATWLGLDPT 1244
Score = 84.2 bits (199), Expect = 5e-16
Identities = 38/83 (45%), Positives = 56/83 (67%)
Frame = +3
Query: 3 LDIVRRDWSQLAAEAGKFILSQILSEQTPDDRLESIQNHLNKLKDDLIGNKMPLSVLAIT 182
LDIVRRDW LA + G F++ QILS+Q+ D +E+IQ L ++ ++++ +P+S I
Sbjct: 1077 LDIVRRDWCDLAKDTGNFVIGQILSDQSRDTIVENIQKRLIEIGENVLNGSVPVSQFEIN 1136
Query: 183 KQLTKNPNEYADKHTQSHVQVAL 251
K LTK+P +Y DK + HV VAL
Sbjct: 1137 KALTKDPQDYPDKKSLPHVHVAL 1159
>AY275833-1|AAP13534.1| 1462|Homo sapiens polymerase (DNA directed),
alpha protein.
Length = 1462
Score = 104 bits (249), Expect = 4e-22
Identities = 43/84 (51%), Positives = 64/84 (76%)
Frame = +2
Query: 254 VNSKNSRRFKKGDIVPYIICEDGTANSATQRAYHIEELKNSEHLKVDFKYYLAHQLHPVI 433
+NS+ R+ K GD V Y+IC+DG+ +A+QRAY E+L+ ++L +D +YYLA Q+HPV+
Sbjct: 1161 INSQGGRKVKAGDTVSYVICQDGSNLTASQRAYAPEQLQKQDNLTIDTQYYLAQQIHPVV 1220
Query: 434 SRICEPIEGMDPARVADCLGLDPS 505
+RICEPI+G+D +A LGLDP+
Sbjct: 1221 ARICEPIDGIDAVLIATWLGLDPT 1244
Score = 84.2 bits (199), Expect = 5e-16
Identities = 38/83 (45%), Positives = 56/83 (67%)
Frame = +3
Query: 3 LDIVRRDWSQLAAEAGKFILSQILSEQTPDDRLESIQNHLNKLKDDLIGNKMPLSVLAIT 182
LDIVRRDW LA + G F++ QILS+Q+ D +E+IQ L ++ ++++ +P+S I
Sbjct: 1077 LDIVRRDWCDLAKDTGNFVIGQILSDQSRDTIVENIQKRLIEIGENVLNGSVPVSQFEIN 1136
Query: 183 KQLTKNPNEYADKHTQSHVQVAL 251
K LTK+P +Y DK + HV VAL
Sbjct: 1137 KALTKDPQDYPDKKSLPHVHVAL 1159
>M81735-1|AAA35768.1| 1107|Homo sapiens DNA polymerase delta protein.
Length = 1107
Score = 47.6 bits (108), Expect = 5e-05
Identities = 30/93 (32%), Positives = 54/93 (58%)
Frame = +3
Query: 3 LDIVRRDWSQLAAEAGKFILSQILSEQTPDDRLESIQNHLNKLKDDLIGNKMPLSVLAIT 182
L+ VRRD L A L ++L ++ P+ + Q+ ++ DL+ N++ +S L IT
Sbjct: 829 LEAVRRDNCPLVANLVTASLRRLLIDRDPEGAVAHAQDVIS----DLLCNRIDISQLVIT 884
Query: 183 KQLTKNPNEYADKHTQSHVQVALRLTVKTVGDS 281
K+LT+ ++YA K Q+HV++A R+ + G +
Sbjct: 885 KELTRAASDYAGK--QAHVELAERMRKRDPGSA 915
Score = 34.3 bits (75), Expect = 0.48
Identities = 23/59 (38%), Positives = 31/59 (52%), Gaps = 1/59 (1%)
Frame = +2
Query: 287 GDIVPYIICEDGTANSATQRAYHIEELKNSEH-LKVDFKYYLAHQLHPVISRICEPIEG 460
GD VPY+I +A ++ + L EH L +D +YYL QL + RI EPI G
Sbjct: 919 GDRVPYVIISAAKGVAAYMKSE--DPLFVLEHSLPIDTQYYLEQQLAKPLLRIFEPILG 975
>M80397-1|AAA58439.1| 1107|Homo sapiens DNA polymerase-delta
catalytic-subunit protein.
Length = 1107
Score = 47.6 bits (108), Expect = 5e-05
Identities = 30/93 (32%), Positives = 54/93 (58%)
Frame = +3
Query: 3 LDIVRRDWSQLAAEAGKFILSQILSEQTPDDRLESIQNHLNKLKDDLIGNKMPLSVLAIT 182
L+ VRRD L A L ++L ++ P+ + Q+ ++ DL+ N++ +S L IT
Sbjct: 829 LEAVRRDNCPLVANLVTASLRRLLIDRDPEGAVAHAQDVIS----DLLCNRIDISQLVIT 884
Query: 183 KQLTKNPNEYADKHTQSHVQVALRLTVKTVGDS 281
K+LT+ ++YA K Q+HV++A R+ + G +
Sbjct: 885 KELTRAASDYAGK--QAHVELAERMRKRDPGSA 915
Score = 34.3 bits (75), Expect = 0.48
Identities = 23/59 (38%), Positives = 31/59 (52%), Gaps = 1/59 (1%)
Frame = +2
Query: 287 GDIVPYIICEDGTANSATQRAYHIEELKNSEH-LKVDFKYYLAHQLHPVISRICEPIEG 460
GD VPY+I +A ++ + L EH L +D +YYL QL + RI EPI G
Sbjct: 919 GDRVPYVIISAAKGVAAYMKSE--DPLFVLEHSLPIDTQYYLEQQLAKPLLRIFEPILG 975
>DQ234348-1|ABB29977.1| 1133|Homo sapiens DNA-directed polymerase
delta 1 protein.
Length = 1133
Score = 47.6 bits (108), Expect = 5e-05
Identities = 30/93 (32%), Positives = 54/93 (58%)
Frame = +3
Query: 3 LDIVRRDWSQLAAEAGKFILSQILSEQTPDDRLESIQNHLNKLKDDLIGNKMPLSVLAIT 182
L+ VRRD L A L ++L ++ P+ + Q+ ++ DL+ N++ +S L IT
Sbjct: 855 LEAVRRDNCPLVANLVTASLRRLLIDRDPEGAVAHAQDVIS----DLLCNRIDISQLVIT 910
Query: 183 KQLTKNPNEYADKHTQSHVQVALRLTVKTVGDS 281
K+LT+ ++YA K Q+HV++A R+ + G +
Sbjct: 911 KELTRAASDYAGK--QAHVELAERMRKRDPGSA 941
Score = 34.3 bits (75), Expect = 0.48
Identities = 23/59 (38%), Positives = 31/59 (52%), Gaps = 1/59 (1%)
Frame = +2
Query: 287 GDIVPYIICEDGTANSATQRAYHIEELKNSEH-LKVDFKYYLAHQLHPVISRICEPIEG 460
GD VPY+I +A ++ + L EH L +D +YYL QL + RI EPI G
Sbjct: 945 GDRVPYVIISAAKGVAAYMKSE--DPLFVLEHSLPIDTQYYLEQQLAKPLLRIFEPILG 1001
>BC008800-1|AAH08800.1| 1107|Homo sapiens polymerase (DNA directed),
delta 1, catalytic subunit 125kDa protein.
Length = 1107
Score = 47.6 bits (108), Expect = 5e-05
Identities = 30/93 (32%), Positives = 54/93 (58%)
Frame = +3
Query: 3 LDIVRRDWSQLAAEAGKFILSQILSEQTPDDRLESIQNHLNKLKDDLIGNKMPLSVLAIT 182
L+ VRRD L A L ++L ++ P+ + Q+ ++ DL+ N++ +S L IT
Sbjct: 829 LEAVRRDNCPLVANLVTASLRRLLIDRDPEGAVAHAQDVIS----DLLCNRIDISQLVIT 884
Query: 183 KQLTKNPNEYADKHTQSHVQVALRLTVKTVGDS 281
K+LT+ ++YA K Q+HV++A R+ + G +
Sbjct: 885 KELTRAASDYAGK--QAHVELAERMRKRDPGSA 915
Score = 34.3 bits (75), Expect = 0.48
Identities = 23/59 (38%), Positives = 31/59 (52%), Gaps = 1/59 (1%)
Frame = +2
Query: 287 GDIVPYIICEDGTANSATQRAYHIEELKNSEH-LKVDFKYYLAHQLHPVISRICEPIEG 460
GD VPY+I +A ++ + L EH L +D +YYL QL + RI EPI G
Sbjct: 919 GDRVPYVIISAAKGVAAYMKSE--DPLFVLEHSLPIDTQYYLEQQLAKPLLRIFEPILG 975
>AY129569-1|AAM76971.1| 1107|Homo sapiens polymerase (DNA directed),
delta 1, catalytic subunit protein.
Length = 1107
Score = 47.6 bits (108), Expect = 5e-05
Identities = 30/93 (32%), Positives = 54/93 (58%)
Frame = +3
Query: 3 LDIVRRDWSQLAAEAGKFILSQILSEQTPDDRLESIQNHLNKLKDDLIGNKMPLSVLAIT 182
L+ VRRD L A L ++L ++ P+ + Q+ ++ DL+ N++ +S L IT
Sbjct: 829 LEAVRRDNCPLVANLVTASLRRLLIDRDPEGAVAHAQDVIS----DLLCNRIDISQLVIT 884
Query: 183 KQLTKNPNEYADKHTQSHVQVALRLTVKTVGDS 281
K+LT+ ++YA K Q+HV++A R+ + G +
Sbjct: 885 KELTRAASDYAGK--QAHVELAERMRKRDPGSA 915
Score = 34.3 bits (75), Expect = 0.48
Identities = 23/59 (38%), Positives = 31/59 (52%), Gaps = 1/59 (1%)
Frame = +2
Query: 287 GDIVPYIICEDGTANSATQRAYHIEELKNSEH-LKVDFKYYLAHQLHPVISRICEPIEG 460
GD VPY+I +A ++ + L EH L +D +YYL QL + RI EPI G
Sbjct: 919 GDRVPYVIISAAKGVAAYMKSE--DPLFVLEHSLPIDTQYYLEQQLAKPLLRIFEPILG 975
>AB209560-1|BAD92797.1| 1011|Homo sapiens polymerase (DNA directed),
delta 1, catalytic subunit 125kDa variant protein.
Length = 1011
Score = 45.6 bits (103), Expect = 2e-04
Identities = 29/84 (34%), Positives = 50/84 (59%)
Frame = +3
Query: 3 LDIVRRDWSQLAAEAGKFILSQILSEQTPDDRLESIQNHLNKLKDDLIGNKMPLSVLAIT 182
L+ VRRD L A L ++L ++ P+ + Q+ ++ DL+ N++ +S L IT
Sbjct: 831 LEAVRRDNCPLVANLVTASLRRLLIDRDPEGAVAHAQDVIS----DLLCNRIDISQLVIT 886
Query: 183 KQLTKNPNEYADKHTQSHVQVALR 254
K+LT+ ++YA K Q+HV++A R
Sbjct: 887 KELTRAASDYAGK--QAHVELAER 908
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 100,104,318
Number of Sequences: 237096
Number of extensions: 1975986
Number of successful extensions: 4310
Number of sequences better than 10.0: 8
Number of HSP's better than 10.0 without gapping: 4124
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4309
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9144232952
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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