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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= br--1005
         (583 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q9U6B8 Cluster: Calcium release-activated calcium chann...   169   3e-41
UniRef50_Q17KQ6 Cluster: Putative uncharacterized protein; n=1; ...   165   9e-40
UniRef50_UPI00015B56E6 Cluster: PREDICTED: similar to conserved ...   122   5e-27
UniRef50_UPI0000D565E1 Cluster: PREDICTED: similar to CG11430-PB...   113   2e-24
UniRef50_Q96SN7 Cluster: Protein orai-2; n=28; Coelomata|Rep: Pr...    86   5e-16
UniRef50_Q8BWG9 Cluster: Calcium release-activated calcium chann...    76   5e-13
UniRef50_Q96D31 Cluster: Calcium release-activated calcium chann...    73   4e-12
UniRef50_Q09232 Cluster: Protein orai; n=2; Caenorhabditis|Rep: ...    69   1e-10
UniRef50_Q9BRQ5 Cluster: Protein orai-3; n=11; Mammalia|Rep: Pro...    57   3e-07
UniRef50_UPI0000E46EE9 Cluster: PREDICTED: similar to proton/ami...    35   1.6  
UniRef50_Q05998 Cluster: Thiamine transporter; n=9; Saccharomyce...    34   2.8  
UniRef50_Q4DDY3 Cluster: Vacuolar transporter chaperone, putativ...    33   3.7  
UniRef50_Q4WPP0 Cluster: Polysaccharide deacetylase family prote...    33   3.7  
UniRef50_Q0SJQ9 Cluster: Probable carveol dehydrogenase; n=1; Rh...    33   4.9  
UniRef50_A6DR82 Cluster: Apolipoprotein N-acyltransferase; n=1; ...    33   4.9  
UniRef50_Q6F0V5 Cluster: Spermidine/putrescine ABC transporter p...    33   6.5  
UniRef50_Q47EW4 Cluster: Acyltransferase 3; n=1; Dechloromonas a...    33   6.5  
UniRef50_Q10Y28 Cluster: Glycosyl transferase, family 39 precurs...    32   8.6  
UniRef50_Q4DKZ7 Cluster: Putative uncharacterized protein; n=2; ...    32   8.6  

>UniRef50_Q9U6B8 Cluster: Calcium release-activated calcium channel
           protein 1; n=17; Eumetazoa|Rep: Calcium
           release-activated calcium channel protein 1 - Drosophila
           melanogaster (Fruit fly)
          Length = 351

 Score =  169 bits (412), Expect = 3e-41
 Identities = 75/90 (83%), Positives = 82/90 (91%)
 Frame = +3

Query: 3   PHERLHWYIEVAWAFSTLLGLILFLIEIAILCWVKFYDLSPTAAWSACVVLIPVMIVFLA 182
           PHERLHWYIE AWAFSTLLGLILFL+EIAILCWVKFYDLSP AAWSACVVLIPVMI+F+A
Sbjct: 236 PHERLHWYIETAWAFSTLLGLILFLLEIAILCWVKFYDLSPPAAWSACVVLIPVMIIFMA 295

Query: 183 FAIHFYMSLATHKYEVTVTGIKELNCSKNR 272
           FAIHFY SL +HKYEVTV+GI+EL   K +
Sbjct: 296 FAIHFYRSLVSHKYEVTVSGIRELEMLKEQ 325


>UniRef50_Q17KQ6 Cluster: Putative uncharacterized protein; n=1;
           Aedes aegypti|Rep: Putative uncharacterized protein -
           Aedes aegypti (Yellowfever mosquito)
          Length = 368

 Score =  165 bits (400), Expect = 9e-40
 Identities = 71/90 (78%), Positives = 81/90 (90%)
 Frame = +3

Query: 3   PHERLHWYIEVAWAFSTLLGLILFLIEIAILCWVKFYDLSPTAAWSACVVLIPVMIVFLA 182
           PHERLHWYIE AWAFSTLLGLILFL EIAILCWVKFYDL+ TAAWSAC+VLIPV+++F+A
Sbjct: 257 PHERLHWYIETAWAFSTLLGLILFLFEIAILCWVKFYDLNTTAAWSACIVLIPVLVIFVA 316

Query: 183 FAIHFYMSLATHKYEVTVTGIKELNCSKNR 272
           FA+HFY SL THKYEVTV+GI+EL   K +
Sbjct: 317 FALHFYRSLMTHKYEVTVSGIRELEMLKEQ 346


>UniRef50_UPI00015B56E6 Cluster: PREDICTED: similar to conserved
           hypothetical protein; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to conserved hypothetical protein -
           Nasonia vitripennis
          Length = 368

 Score =  122 bits (295), Expect = 5e-27
 Identities = 55/90 (61%), Positives = 74/90 (82%), Gaps = 1/90 (1%)
 Frame = +3

Query: 3   PHERLHWYIEVAWAFSTLLGLILFLIEIAILCWVKFYDLSPTAAWSACVVLIPVMIVFLA 182
           PHER+  +IE+AWAFST+LGL LFL+E+AILCWVKF+D S TAA ++ V++IPV+IVF+A
Sbjct: 268 PHERMRGFIELAWAFSTVLGLFLFLVEVAILCWVKFWDYSFTAATASTVIVIPVLIVFIA 327

Query: 183 FAIHFYMSLATHKYEVTVTGIKEL-NCSKN 269
           FA+HFY SL  +K E +V+ +KEL N  +N
Sbjct: 328 FAVHFYHSLVVYKCEASVSDMKELENIKRN 357


>UniRef50_UPI0000D565E1 Cluster: PREDICTED: similar to CG11430-PB,
           isoform B; n=2; Endopterygota|Rep: PREDICTED: similar to
           CG11430-PB, isoform B - Tribolium castaneum
          Length = 320

 Score =  113 bits (273), Expect = 2e-24
 Identities = 50/88 (56%), Positives = 68/88 (77%)
 Frame = +3

Query: 3   PHERLHWYIEVAWAFSTLLGLILFLIEIAILCWVKFYDLSPTAAWSACVVLIPVMIVFLA 182
           PHER+  +IE+AWAFST+LGL LFL+E+AILCWVKF+D S TAA +A V++IPV+I F+ 
Sbjct: 223 PHERMRGFIELAWAFSTVLGLFLFLVEVAILCWVKFWDYSFTAATAATVIVIPVLITFVL 282

Query: 183 FAIHFYMSLATHKYEVTVTGIKELNCSK 266
           FA+HFY SL  +K   +V  +++L   K
Sbjct: 283 FAVHFYHSLVVYKCNASVNDMEKLENMK 310


>UniRef50_Q96SN7 Cluster: Protein orai-2; n=28; Coelomata|Rep:
           Protein orai-2 - Homo sapiens (Human)
          Length = 254

 Score = 86.2 bits (204), Expect = 5e-16
 Identities = 42/101 (41%), Positives = 60/101 (59%), Gaps = 16/101 (15%)
 Frame = +3

Query: 3   PHERLHWYIEVAWAFSTLLGLILFLIEIAILCWVKFYDLSPT------------AAWSAC 146
           PHER+H YIE+AW FST+LG++LFL E+ +LCW+KF  +                 W A 
Sbjct: 138 PHERMHPYIELAWGFSTVLGILLFLAEVVLLCWIKFLPVDARRQPGPPPGPGSHTGWQAA 197

Query: 147 ----VVLIPVMIVFLAFAIHFYMSLATHKYEVTVTGIKELN 257
               ++++PV ++F+ F IHFY SL  HK E     I+EL+
Sbjct: 198 LVSTIIMVPVGLIFVVFTIHFYRSLVRHKTERHNREIEELH 238


>UniRef50_Q8BWG9 Cluster: Calcium release-activated calcium channel
           protein 1; n=15; Euteleostomi|Rep: Calcium
           release-activated calcium channel protein 1 - Mus
           musculus (Mouse)
          Length = 304

 Score = 76.2 bits (179), Expect = 5e-13
 Identities = 44/114 (38%), Positives = 63/114 (55%), Gaps = 30/114 (26%)
 Frame = +3

Query: 3   PHERLHWYIEVAWAFSTLLGLILFLIEIAILCWVKFYDL-------SPT----------- 128
           PHER+H +IE+AWAFST++G +LFL E+ +LCWVKF  L       SPT           
Sbjct: 166 PHERMHRHIELAWAFSTVIGTLLFLAEVVLLCWVKFLPLKRQAGQPSPTKPPAESVIVAN 225

Query: 129 ------------AAWSACVVLIPVMIVFLAFAIHFYMSLATHKYEVTVTGIKEL 254
                       AA ++  +++P  +VF+ FA+HFY SL +HK +     + EL
Sbjct: 226 HSDSSGITPGEAAAIASTAIMVPCGLVFIVFAVHFYRSLVSHKTDRQFQELNEL 279


>UniRef50_Q96D31 Cluster: Calcium release-activated calcium channel
           protein 1; n=8; Eutheria|Rep: Calcium release-activated
           calcium channel protein 1 - Homo sapiens (Human)
          Length = 301

 Score = 73.3 bits (172), Expect = 4e-12
 Identities = 41/113 (36%), Positives = 61/113 (53%), Gaps = 29/113 (25%)
 Frame = +3

Query: 3   PHERLHWYIEVAWAFSTLLGLILFLIEIAILCWVKFYDL-----------SPTAAWSAC- 146
           PHER+H +IE+AWAFST++G +LFL E+ +LCWVKF  L            P A+ +A  
Sbjct: 164 PHERMHRHIELAWAFSTVIGTLLFLAEVVLLCWVKFLPLKKQPGQPRPTSKPPASGAAAN 223

Query: 147 -----------------VVLIPVMIVFLAFAIHFYMSLATHKYEVTVTGIKEL 254
                             +++P  ++F+ FA+HFY SL +HK +     + EL
Sbjct: 224 VSTSGITPGQAAAIASTTIMVPFGLIFIVFAVHFYRSLVSHKTDRQFQELNEL 276


>UniRef50_Q09232 Cluster: Protein orai; n=2; Caenorhabditis|Rep:
           Protein orai - Caenorhabditis elegans
          Length = 293

 Score = 68.5 bits (160), Expect = 1e-10
 Identities = 29/73 (39%), Positives = 50/73 (68%), Gaps = 1/73 (1%)
 Frame = +3

Query: 3   PHERLHWYIEVAWAFSTLLGLILFLIEIAILCWVKFYDLS-PTAAWSACVVLIPVMIVFL 179
           PH +L +YI+++W FST +GL+LFL+EI ++ +VKF  +  PTA +    +L+PV +VF+
Sbjct: 186 PHIKLKFYIDLSWLFSTCIGLLLFLVEIGVIFYVKFTAVGYPTAGYITTAMLVPVGVVFV 245

Query: 180 AFAIHFYMSLATH 218
            F+   + +  +H
Sbjct: 246 VFSYLIHKNRVSH 258


>UniRef50_Q9BRQ5 Cluster: Protein orai-3; n=11; Mammalia|Rep:
           Protein orai-3 - Homo sapiens (Human)
          Length = 295

 Score = 57.2 bits (132), Expect = 3e-07
 Identities = 22/36 (61%), Positives = 28/36 (77%)
 Frame = +3

Query: 3   PHERLHWYIEVAWAFSTLLGLILFLIEIAILCWVKF 110
           PH+RLH Y+E+AW FST LG  LFL E+ ++ WVKF
Sbjct: 139 PHQRLHRYVELAWGFSTALGTFLFLAEVVLVGWVKF 174



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 19/43 (44%), Positives = 30/43 (69%)
 Frame = +3

Query: 129 AAWSACVVLIPVMIVFLAFAIHFYMSLATHKYEVTVTGIKELN 257
           AA ++  +++PV +VF+AFA+HFY SL  HK +     ++ELN
Sbjct: 244 AAMASTAIMVPVGLVFVAFALHFYRSLVAHKTDRYKQELEELN 286


>UniRef50_UPI0000E46EE9 Cluster: PREDICTED: similar to proton/amino
           acid transporter 1; n=1; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to proton/amino acid
           transporter 1 - Strongylocentrotus purpuratus
          Length = 476

 Score = 34.7 bits (76), Expect = 1.6
 Identities = 24/71 (33%), Positives = 33/71 (46%)
 Frame = +3

Query: 3   PHERLHWYIEVAWAFSTLLGLILFLIEIAILCWVKFYDLSPTAAWSACVVLIPVMIVFLA 182
           P ER H   E  + F T++ LI   + IAI     F  L    A S   ++ P +I  L 
Sbjct: 381 PQERYHTLAE--YVFRTIIVLITMTLAIAIPQLPLFISLVGAMASSTLALIFPPVIEELT 438

Query: 183 FAIHFYMSLAT 215
           F+ H Y S A+
Sbjct: 439 FSYHGYASKAS 449


>UniRef50_Q05998 Cluster: Thiamine transporter; n=9;
           Saccharomycetales|Rep: Thiamine transporter -
           Saccharomyces cerevisiae (Baker's yeast)
          Length = 598

 Score = 33.9 bits (74), Expect = 2.8
 Identities = 30/128 (23%), Positives = 52/128 (40%), Gaps = 3/128 (2%)
 Frame = +3

Query: 30  EVAWAFSTLLGLILFLIEIAILCWVKFYDLSPTAAWSACVVLIPV--MIVFLAFAIHFYM 203
           +VA     L+G I+F +  A    +K Y ++    WS       +  M+++LA   H   
Sbjct: 166 KVAMTTKELIGFIIFHVLTAFCYLMKPYHMNYILIWSCVATFFSMLGMVIYLAKQAHGVG 225

Query: 204 SLATHKYEVTVTGIKELNCSKNRSKW-ATTTPE*TA*RCWTKVGSSDLLLFTGIVFSLLL 380
            L T          K        S W  + +P  T    +++ GSS+  ++ G + +LL+
Sbjct: 226 ELFTSTKSTATGSTKAWAWVYMISYWFGSVSPGSTNQSDYSRFGSSNWAIWAGTICALLI 285

Query: 381 VLLKIMYF 404
               I  F
Sbjct: 286 PTTLIPVF 293


>UniRef50_Q4DDY3 Cluster: Vacuolar transporter chaperone, putative;
           n=6; Trypanosomatidae|Rep: Vacuolar transporter
           chaperone, putative - Trypanosoma cruzi
          Length = 180

 Score = 33.5 bits (73), Expect = 3.7
 Identities = 18/53 (33%), Positives = 29/53 (54%)
 Frame = +3

Query: 66  ILFLIEIAILCWVKFYDLSPTAAWSACVVLIPVMIVFLAFAIHFYMSLATHKY 224
           I  +I +  L  + F D S TA   A +VL+PV I+F+A+++  +   A   Y
Sbjct: 77  ISVMIGLMSLTLLNFGDTSSTAPELAGLVLLPVSIIFMAYSLFIFRDRANKIY 129


>UniRef50_Q4WPP0 Cluster: Polysaccharide deacetylase family protein;
           n=4; Trichocomaceae|Rep: Polysaccharide deacetylase
           family protein - Aspergillus fumigatus (Sartorya
           fumigata)
          Length = 254

 Score = 33.5 bits (73), Expect = 3.7
 Identities = 22/75 (29%), Positives = 34/75 (45%)
 Frame = +2

Query: 176 FGVRNTFLHVPGDAQVRSHGDRYQRIKLLKEQIEMGDHDARMNSLTLLDQSRVV*SFTIY 355
           +G R+TF  + G  +   HGD     ++ +E  ++G H      LT LD   +V   T  
Sbjct: 76  YGARSTFF-LNGQNKGSFHGDAAVVRRIFEEGHQVGSHTWGHPYLTSLDYPAIVAQMTQL 134

Query: 356 WDCF*PFIGFIKNYV 400
            D F   +GF   Y+
Sbjct: 135 EDAFMQVLGFYPTYM 149


>UniRef50_Q0SJQ9 Cluster: Probable carveol dehydrogenase; n=1;
           Rhodococcus sp. RHA1|Rep: Probable carveol dehydrogenase
           - Rhodococcus sp. (strain RHA1)
          Length = 273

 Score = 33.1 bits (72), Expect = 4.9
 Identities = 14/31 (45%), Positives = 17/31 (54%)
 Frame = +3

Query: 78  IEIAILCWVKFYDLSPTAAWSACVVLIPVMI 170
           IEI    W    D+  T AW AC  ++PVMI
Sbjct: 116 IEIEDDAWQTMLDVKVTGAWKACKAVVPVMI 146


>UniRef50_A6DR82 Cluster: Apolipoprotein N-acyltransferase; n=1;
           Lentisphaera araneosa HTCC2155|Rep: Apolipoprotein
           N-acyltransferase - Lentisphaera araneosa HTCC2155
          Length = 572

 Score = 33.1 bits (72), Expect = 4.9
 Identities = 14/31 (45%), Positives = 18/31 (58%)
 Frame = +3

Query: 6   HERLHWYIEVAWAFSTLLGLILFLIEIAILC 98
           H+R ++YI  AW F   LG   FL  I +LC
Sbjct: 56  HDRGNFYIGSAWGFGYFLGTFYFLYPIFLLC 86


>UniRef50_Q6F0V5 Cluster: Spermidine/putrescine ABC transporter
           permease component; n=3; Mollicutes|Rep:
           Spermidine/putrescine ABC transporter permease component
           - Mesoplasma florum (Acholeplasma florum)
          Length = 331

 Score = 32.7 bits (71), Expect = 6.5
 Identities = 22/85 (25%), Positives = 44/85 (51%), Gaps = 1/85 (1%)
 Frame = +3

Query: 39  WAFSTLLGLILFLIEIAILCWVKFYDLSPTAAWSACVVLIPVMIVFLAFAI-HFYMSLAT 215
           W   T+   I  L+++  L  + F  ++P+A  +   ++I +  +F+ FAI   Y SL +
Sbjct: 152 WLLVTMPMWISMLLKVLGLRSL-FLIMAPSALGTQIAIIIGMTYMFIPFAITPIYDSLDS 210

Query: 216 HKYEVTVTGIKELNCSKNRSKWATT 290
            + ++    + +L CSK ++ W  T
Sbjct: 211 RRRDIEEAAM-DLGCSKYKTFWGVT 234


>UniRef50_Q47EW4 Cluster: Acyltransferase 3; n=1; Dechloromonas
           aromatica RCB|Rep: Acyltransferase 3 - Dechloromonas
           aromatica (strain RCB)
          Length = 397

 Score = 32.7 bits (71), Expect = 6.5
 Identities = 16/52 (30%), Positives = 32/52 (61%)
 Frame = +3

Query: 30  EVAWAFSTLLGLILFLIEIAILCWVKFYDLSPTAAWSACVVLIPVMIVFLAF 185
           E+A++   L G++LFL+   ++ + K   L P   WSA + + P++I F+++
Sbjct: 311 ELAYSIYLLHGIVLFLLFRYVIGFEKSKLLQPIDYWSAIIAVSPILI-FISY 361


>UniRef50_Q10Y28 Cluster: Glycosyl transferase, family 39 precursor;
           n=1; Trichodesmium erythraeum IMS101|Rep: Glycosyl
           transferase, family 39 precursor - Trichodesmium
           erythraeum (strain IMS101)
          Length = 666

 Score = 32.3 bits (70), Expect = 8.6
 Identities = 34/122 (27%), Positives = 51/122 (41%), Gaps = 5/122 (4%)
 Frame = +3

Query: 57  LGLILFLIEIAILCWVKFYDLSPTAAWSACVVLIPVMIVFLAFAIHFYMSLATHKYEVTV 236
           LGL  F      +C   F+ +S T   S  + ++P   + LA    F+ ++  H+Y ++ 
Sbjct: 372 LGLFAFFW---FICIFAFFSISATKLPSYVLPIMPAAAILLAL---FWSNIILHRYSLSS 425

Query: 237 TGIKELNCSKNRSKWATTTPE*TA*RCW--TKVGSSDLLLFT---GIVFSLLLVLLKIMY 401
              K  N S   S  AT  P     R    T    S  L F+    I+F L+L L  I  
Sbjct: 426 QTNKPENNSTQSSFKATNNPTQPISRLTRNTSKSKSKFLSFSVVANIIFLLILALAIIYS 485

Query: 402 FS 407
           F+
Sbjct: 486 FN 487


>UniRef50_Q4DKZ7 Cluster: Putative uncharacterized protein; n=2;
           Trypanosoma cruzi|Rep: Putative uncharacterized protein
           - Trypanosoma cruzi
          Length = 229

 Score = 32.3 bits (70), Expect = 8.6
 Identities = 18/56 (32%), Positives = 25/56 (44%), Gaps = 1/56 (1%)
 Frame = +2

Query: 125 DGSLVGLCGPYTCYDCI-FGVRNTFLHVPGDAQVRSHGDRYQRIKLLKEQIEMGDH 289
           D ++V  CG   CYDCI  G+ N  + V    QV    D  ++ K     +   DH
Sbjct: 76  DPAVVDTCGHAFCYDCINLGIENGCVPVASTVQVEDKEDEGRKEKNELSVVSEKDH 131


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 572,084,921
Number of Sequences: 1657284
Number of extensions: 11215763
Number of successful extensions: 28825
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 28057
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 28818
length of database: 575,637,011
effective HSP length: 96
effective length of database: 416,537,747
effective search space used: 40404161459
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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