Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= br--0821
(597 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q13098 Cluster: COP9 signalosome complex subunit 1; n=3... 107 3e-22
UniRef50_Q4QQY0 Cluster: MGC115579 protein; n=2; Tetrapoda|Rep: ... 102 6e-21
UniRef50_Q9VVU5 Cluster: COP9 signalosome complex subunit 1b; n=... 90 1e-17
UniRef50_Q2PQ78 Cluster: COP9 signalosome complex subunit 1; n=2... 63 4e-09
UniRef50_Q9VJR9 Cluster: CG4697-PA; n=2; Sophophora|Rep: CG4697-... 60 5e-08
UniRef50_P45432 Cluster: COP9 signalosome complex subunit 1; n=8... 48 1e-04
UniRef50_Q9GS00 Cluster: COP9 signalosome complex subunit 1; n=2... 44 0.002
UniRef50_Q56UN7 Cluster: COP9 signalosome subunit 1; n=10; Eurot... 40 0.034
UniRef50_Q0V4K2 Cluster: Putative uncharacterized protein; n=1; ... 40 0.044
UniRef50_Q6CJH2 Cluster: Similar to sp|P28817 Saccharomyces cere... 35 1.3
UniRef50_UPI00006CBFF4 Cluster: hypothetical protein TTHERM_0041... 33 3.9
UniRef50_UPI0000E46340 Cluster: PREDICTED: hypothetical protein;... 33 6.7
UniRef50_Q5DHQ2 Cluster: SJCHGC00975 protein; n=2; Schistosoma j... 33 6.7
UniRef50_Q54UK1 Cluster: Putative uncharacterized protein; n=1; ... 33 6.7
UniRef50_Q4S496 Cluster: Chromosome 1 SCAF14742, whole genome sh... 32 8.9
>UniRef50_Q13098 Cluster: COP9 signalosome complex subunit 1; n=33;
Eumetazoa|Rep: COP9 signalosome complex subunit 1 - Homo
sapiens (Human)
Length = 471
Score = 107 bits (256), Expect = 3e-22
Identities = 52/102 (50%), Positives = 68/102 (66%), Gaps = 3/102 (2%)
Frame = +3
Query: 255 PTLDLETYAASYTGFAKLYRLMFVADHCPSLRLEALKMAISYVMTTYNVNLYHTLHKKLS 434
P+LDLE YAASY+G ++ RL F+ADHCP+LR+EALKMA+S+V T+NV++Y +H+KLS
Sbjct: 24 PSLDLEQYAASYSGLMRIERLQFIADHCPTLRVEALKMALSFVQRTFNVDMYEEIHRKLS 83
Query: 435 EAVAS-AGLPDIAGSQDI--PVLDTIWVNQKQKKLP*NWEKL 551
EA PD + P LDT WV +KK EKL
Sbjct: 84 EATRELQNAPDAIPESGVEPPALDTAWVEATRKKALLKLEKL 125
>UniRef50_Q4QQY0 Cluster: MGC115579 protein; n=2; Tetrapoda|Rep:
MGC115579 protein - Xenopus laevis (African clawed frog)
Length = 250
Score = 102 bits (245), Expect = 6e-21
Identities = 51/102 (50%), Positives = 67/102 (65%), Gaps = 3/102 (2%)
Frame = +3
Query: 255 PTLDLETYAASYTGFAKLYRLMFVADHCPSLRLEALKMAISYVMTTYNVNLYHTLHKKLS 434
PTLDLE YA+SY+ ++ RL F+AD CP LR+EALKMA+S+V T+NV++Y +H+KL+
Sbjct: 40 PTLDLEQYASSYSSLMRIERLQFIADRCPQLRVEALKMALSFVQRTFNVDVYEDIHRKLT 99
Query: 435 EAVASA-GLPDIA--GSQDIPVLDTIWVNQKQKKLP*NWEKL 551
EA PD GS + P LDT WV +KK EKL
Sbjct: 100 EASREVQNAPDAVPEGSMEPPPLDTTWVEATRKKALLKLEKL 141
Score = 35.5 bits (78), Expect = 0.96
Identities = 17/37 (45%), Positives = 25/37 (67%), Gaps = 2/37 (5%)
Frame = +1
Query: 154 PPIMFEMNTA-EPMQVDIPPEDNENNETEC-YVVENP 258
P +F + +A EPMQ+D P+D++ N + YVVENP
Sbjct: 4 PVQVFNLQSAVEPMQIDADPQDDQQNMPDVNYVVENP 40
>UniRef50_Q9VVU5 Cluster: COP9 signalosome complex subunit 1b; n=13;
Eukaryota|Rep: COP9 signalosome complex subunit 1b -
Drosophila melanogaster (Fruit fly)
Length = 525
Score = 89.8 bits (213), Expect(2) = 1e-17
Identities = 39/61 (63%), Positives = 49/61 (80%)
Frame = +3
Query: 255 PTLDLETYAASYTGFAKLYRLMFVADHCPSLRLEALKMAISYVMTTYNVNLYHTLHKKLS 434
P++DLE YA Y G +L+RL++VAD CP L +EALKMAI+YV TTYNVNLY LHK+LS
Sbjct: 41 PSIDLEVYANQYAGIVRLHRLIYVADVCPVLAVEALKMAITYVQTTYNVNLYQVLHKRLS 100
Query: 435 E 437
+
Sbjct: 101 D 101
Score = 46.4 bits (105), Expect = 5e-04
Identities = 24/37 (64%), Positives = 26/37 (70%), Gaps = 2/37 (5%)
Frame = +1
Query: 154 PPIMFEMNTAEPMQVDIPP--EDNENNETECYVVENP 258
PP+M N EPMQVDI P EDNENNE + VVENP
Sbjct: 7 PPLM--QNAVEPMQVDIAPPNEDNENNEEQQIVVENP 41
Score = 22.6 bits (46), Expect(2) = 1e-17
Identities = 15/41 (36%), Positives = 19/41 (46%), Gaps = 1/41 (2%)
Frame = +3
Query: 432 SEAVASA-GLPDIAGSQDIPVLDTIWVNQKQKKLP*NWEKL 551
++ VA A G A +D D WV+ K KK EKL
Sbjct: 137 AQPVAQAQGQAQPAVEKDAFAYDAAWVDTKMKKAALKLEKL 177
>UniRef50_Q2PQ78 Cluster: COP9 signalosome complex subunit 1; n=2;
Dictyostelium discoideum|Rep: COP9 signalosome complex
subunit 1 - Dictyostelium discoideum (Slime mold)
Length = 458
Score = 63.3 bits (147), Expect = 4e-09
Identities = 27/55 (49%), Positives = 39/55 (70%)
Frame = +3
Query: 264 DLETYAASYTGFAKLYRLMFVADHCPSLRLEALKMAISYVMTTYNVNLYHTLHKK 428
DLETY +Y+GF K++RL+F+AD+C L +EA MA+ V T N+ LY+T+ K
Sbjct: 31 DLETYINNYSGFTKIHRLIFIADNCKQLEVEAYNMALKEVQKTPNLELYNTIINK 85
>UniRef50_Q9VJR9 Cluster: CG4697-PA; n=2; Sophophora|Rep: CG4697-PA
- Drosophila melanogaster (Fruit fly)
Length = 364
Score = 59.7 bits (138), Expect = 5e-08
Identities = 28/57 (49%), Positives = 38/57 (66%)
Frame = +3
Query: 261 LDLETYAASYTGFAKLYRLMFVADHCPSLRLEALKMAISYVMTTYNVNLYHTLHKKL 431
L L +YA YT +L RL F+A CP L + AL++A+++V TTYNV LY L+K L
Sbjct: 9 LHLPSYADRYTDIPRLIRLKFIAQVCPELSVLALELALNHVKTTYNVKLYDELYKTL 65
>UniRef50_P45432 Cluster: COP9 signalosome complex subunit 1; n=8;
Magnoliophyta|Rep: COP9 signalosome complex subunit 1 -
Arabidopsis thaliana (Mouse-ear cress)
Length = 441
Score = 48.4 bits (110), Expect = 1e-04
Identities = 25/73 (34%), Positives = 40/73 (54%), Gaps = 3/73 (4%)
Frame = +3
Query: 261 LDLETYAASYTGFAKLYRLMFVADHC---PSLRLEALKMAISYVMTTYNVNLYHTLHKKL 431
LD+E YAA Y G K+ RL+F+A+HC +L+ +AL+MA + N L+ + K+
Sbjct: 34 LDIEAYAALYKGRTKIMRLLFIANHCGGNHALQFDALRMAYDEIKKGENTQLFREVVNKI 93
Query: 432 SEAVASAGLPDIA 470
+ D+A
Sbjct: 94 GNRLGEKYGMDLA 106
>UniRef50_Q9GS00 Cluster: COP9 signalosome complex subunit 1; n=2;
Caenorhabditis|Rep: COP9 signalosome complex subunit 1 -
Caenorhabditis elegans
Length = 601
Score = 44.4 bits (100), Expect = 0.002
Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 1/86 (1%)
Frame = +3
Query: 261 LDLETYAASYTGFAKLYRLMFVADHCPSLRLEALKMAISYVMT-TYNVNLYHTLHKKLSE 437
+D+E+ A SY A R F+A HCP LR +A I+Y+ T ++ Y +L
Sbjct: 84 IDIESLACSYDSNAFFLRARFIARHCPILRADAYISLINYLKEHTTDITHYVAFFNELES 143
Query: 438 AVASAGLPDIAGSQDIPVLDTIWVNQ 515
+A + + IP+ D W+ +
Sbjct: 144 ELARKEFKNRQLNFQIPLRDQKWIEE 169
>UniRef50_Q56UN7 Cluster: COP9 signalosome subunit 1; n=10;
Eurotiomycetidae|Rep: COP9 signalosome subunit 1 -
Emericella nidulans (Aspergillus nidulans)
Length = 498
Score = 40.3 bits (90), Expect = 0.034
Identities = 27/90 (30%), Positives = 43/90 (47%)
Frame = +3
Query: 255 PTLDLETYAASYTGFAKLYRLMFVADHCPSLRLEALKMAISYVMTTYNVNLYHTLHKKLS 434
P +LE+Y A+YTG + RL + L ++ALK AI+ + +V Y
Sbjct: 50 PKFELESYIANYTGRTRFNRLYLIGTCSSYLAVDALKAAIAEAKSGKDVARY-------- 101
Query: 435 EAVASAGLPDIAGSQDIPVLDTIWVNQKQK 524
A L D+A ++ +D+ WV + QK
Sbjct: 102 -LRAVQALADVAPNEPEATIDSDWVERSQK 130
>UniRef50_Q0V4K2 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 461
Score = 39.9 bits (89), Expect = 0.044
Identities = 15/41 (36%), Positives = 27/41 (65%)
Frame = +3
Query: 255 PTLDLETYAASYTGFAKLYRLMFVADHCPSLRLEALKMAIS 377
P DLE+Y ++Y+GF ++ RL + H P ++A ++AI+
Sbjct: 26 PKFDLESYISNYSGFTRVDRLHHIGSHSPYFAVDAYRLAIA 66
>UniRef50_Q6CJH2 Cluster: Similar to sp|P28817 Saccharomyces
cerevisiae YDR036c singleton; n=1; Kluyveromyces
lactis|Rep: Similar to sp|P28817 Saccharomyces
cerevisiae YDR036c singleton - Kluyveromyces lactis
(Yeast) (Candida sphaerica)
Length = 504
Score = 35.1 bits (77), Expect = 1.3
Identities = 20/48 (41%), Positives = 28/48 (58%)
Frame = +1
Query: 1 RHEKCRCQDET***RYLLKNTKRVVKLRFSDELVFIVDSKFRVFSLKK 144
RH CR Q ++ R++LK V +LRF E+ F VDS RV +L +
Sbjct: 3 RHSYCRAQQQSL--RHVLKTRLAVNQLRFMSEVKFRVDSTARVVTLDR 48
>UniRef50_UPI00006CBFF4 Cluster: hypothetical protein
TTHERM_00411300; n=1; Tetrahymena thermophila SB210|Rep:
hypothetical protein TTHERM_00411300 - Tetrahymena
thermophila SB210
Length = 600
Score = 33.5 bits (73), Expect = 3.9
Identities = 18/63 (28%), Positives = 38/63 (60%), Gaps = 1/63 (1%)
Frame = +1
Query: 97 LVFIVDSKFRVFSLKKA*NPPIMFEMNT-AEPMQVDIPPEDNENNETECYVVENPPWIWK 273
++F+V S++ ++ LK A PP ++NT + Q+++ ++NE T+ +V +N + K
Sbjct: 243 MLFLVGSQYILYRLKTAPPPPNPPQINTQQQQQQLELAQKNNEIKNTQKFVQQNMDGLNK 302
Query: 274 HTL 282
+ L
Sbjct: 303 NPL 305
>UniRef50_UPI0000E46340 Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 1156
Score = 32.7 bits (71), Expect = 6.7
Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 10/70 (14%)
Frame = +3
Query: 321 FVADHCPSLRLEALKMAISYVMTTYNV---------NLYHTLHKKLSEAVASAGLPDIAG 473
++ADHCP L E A + MT+Y + L TL+ + G+ D+AG
Sbjct: 119 WLADHCPHLTSELSTYANDHKMTSYFLQIASFDLCNELQQTLYGRPGSVSLERGVDDVAG 178
Query: 474 SQDI-PVLDT 500
S D V+DT
Sbjct: 179 SADFNGVIDT 188
>UniRef50_Q5DHQ2 Cluster: SJCHGC00975 protein; n=2; Schistosoma
japonicum|Rep: SJCHGC00975 protein - Schistosoma
japonicum (Blood fluke)
Length = 357
Score = 32.7 bits (71), Expect = 6.7
Identities = 26/101 (25%), Positives = 49/101 (48%), Gaps = 4/101 (3%)
Frame = +3
Query: 276 YAASYTGFAKLYRLMFVADHCPSLRLEALKMAISYVMTT-YNVNLYHTLHKKLSE-AVAS 449
Y +S AK Y L + + + +K ++ ++++ YN+ L+H K + E + S
Sbjct: 100 YNSSRLKIAK-YNLQNLTVFHKNQSVHQIKYNLNEILSSSYNI-LFHAFKKDIGENRITS 157
Query: 450 AGLPDIAG-SQDIPVLDTIWVNQKQKKLP*NWEKL-RILDF 566
L D D+ V+ +W+++ K L +W+ L LDF
Sbjct: 158 RKLNDYTSIKHDVQVIFRLWIDKTMKLLKGDWQDLNECLDF 198
>UniRef50_Q54UK1 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 863
Score = 32.7 bits (71), Expect = 6.7
Identities = 19/44 (43%), Positives = 26/44 (59%)
Frame = -2
Query: 173 ISNIIGGF*AFFNENTRNLLSTMKTNSSENRNFTTLLVFFNKYL 42
+SNII FFNEN +LST+ NS+ N N T+ +NK +
Sbjct: 186 LSNIIANL-IFFNEN---VLSTISINSNSNNNNNTIKEKYNKII 225
>UniRef50_Q4S496 Cluster: Chromosome 1 SCAF14742, whole genome shotgun
sequence; n=5; Euteleostomi|Rep: Chromosome 1 SCAF14742,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 2660
Score = 32.3 bits (70), Expect = 8.9
Identities = 20/59 (33%), Positives = 31/59 (52%)
Frame = +3
Query: 315 LMFVADHCPSLRLEALKMAISYVMTTYNVNLYHTLHKKLSEAVASAGLPDIAGSQDIPV 491
L F+ DH P + LE ++ IS + +T N+NL+ T ++ + PD A Q PV
Sbjct: 827 LNFLYDHNPKVFLENIRTFISELNSTANINLFLTELREEDTTSSMYPRPDGATVQTRPV 885
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 597,092,306
Number of Sequences: 1657284
Number of extensions: 12251085
Number of successful extensions: 30714
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 29472
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 30691
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 41902926763
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -