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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= br--0423
         (449 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

X87176-1|CAA60643.1|  736|Homo sapiens 17beta-hydroxysteroid deh...    76   6e-14
BC003098-1|AAH03098.1|  736|Homo sapiens hydroxysteroid (17-beta...    76   6e-14
AF057740-1|AAD08652.1|  736|Homo sapiens 17-beta-hydroxysteroid ...    76   6e-14
U63296-1|AAB53034.1|  143|Homo sapiens 15-hydroxyprostaglandin d...    37   0.037
L76465-1|AAA89175.1|  266|Homo sapiens NAD+-dependent 15-hydroxy...    37   0.037
J05594-1|AAA89174.1|  266|Homo sapiens NAD+-dependent 15-hydroxy...    37   0.037
DQ903072-1|ABI75347.1|  266|Homo sapiens hydroxyprostaglandin de...    37   0.037
BC018986-1|AAH18986.1|  266|Homo sapiens hydroxyprostaglandin de...    37   0.037
X82460-1|CAA57843.1|  178|Homo sapiens 15-hydroxy prostaglandin ...    36   0.084
BC007337-1|AAH07337.1|  339|Homo sapiens dehydrogenase/reductase...    31   2.4  
BC000637-1|AAH00637.1|  339|Homo sapiens dehydrogenase/reductase...    31   2.4  
AY359031-1|AAQ89390.1|  289|Homo sapiens oxidoreductase/S-2 H pr...    31   2.4  
AF151844-1|AAD34081.1|  339|Homo sapiens CGI-86 protein protein.       31   2.4  
AF126782-1|AAF06941.1|  289|Homo sapiens retinal short-chain deh...    31   2.4  
BC095451-1|AAH95451.1|  418|Homo sapiens hydroxysteroid dehydrog...    30   4.2  
AY093428-1|AAM14670.1|  418|Homo sapiens hydroxysteroid dehydrog...    30   4.2  
AL162732-1|CAM17152.1|  418|Homo sapiens hydroxysteroid dehydrog...    30   4.2  

>X87176-1|CAA60643.1|  736|Homo sapiens 17beta-hydroxysteroid
           dehydrogenase protein.
          Length = 736

 Score = 75.8 bits (178), Expect = 6e-14
 Identities = 55/146 (37%), Positives = 67/146 (45%), Gaps = 1/146 (0%)
 Frame = +3

Query: 15  LRFDGRVAVVTXXXXXXXXXXXXXXXSRGAKVVVNDLGSARDGAGK-SNAADAVVKEIKD 191
           LRFDGRV +VT                RGA VVVNDLG    G GK S AAD VV+EI+ 
Sbjct: 5   LRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEIRR 64

Query: 192 KGGVAVADYNSVVEGEXXXXXXXXXXXXXXFLSTMLAFSVIRAXLK*LXXTXT*FSXSI* 371
           +GG AVA+Y+SV EGE               +         R+  +              
Sbjct: 65  RGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRVHL 124

Query: 372 KVLFKTTYAAWXTFILLKYGRIVMTS 449
           +  F+ T AAW      KYGRI+MTS
Sbjct: 125 RGSFQVTRAAWEHMKKQKYGRIIMTS 150



 Score = 60.5 bits (140), Expect = 3e-09
 Identities = 25/49 (51%), Positives = 37/49 (75%)
 Frame = +2

Query: 233 GGEANKNAIDNFGRIDILINNAGILRDKSXTKMTXXDXDLIQXVHLKGA 379
           G +  K A+D FGRID+++NNAGILRD+S  +++  D D+I  VHL+G+
Sbjct: 79  GEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRVHLRGS 127


>BC003098-1|AAH03098.1|  736|Homo sapiens hydroxysteroid (17-beta)
           dehydrogenase 4 protein.
          Length = 736

 Score = 75.8 bits (178), Expect = 6e-14
 Identities = 55/146 (37%), Positives = 67/146 (45%), Gaps = 1/146 (0%)
 Frame = +3

Query: 15  LRFDGRVAVVTXXXXXXXXXXXXXXXSRGAKVVVNDLGSARDGAGK-SNAADAVVKEIKD 191
           LRFDGRV +VT                RGA VVVNDLG    G GK S AAD VV+EI+ 
Sbjct: 5   LRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEIRR 64

Query: 192 KGGVAVADYNSVVEGEXXXXXXXXXXXXXXFLSTMLAFSVIRAXLK*LXXTXT*FSXSI* 371
           +GG AVA+Y+SV EGE               +         R+  +              
Sbjct: 65  RGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRVHL 124

Query: 372 KVLFKTTYAAWXTFILLKYGRIVMTS 449
           +  F+ T AAW      KYGRI+MTS
Sbjct: 125 RGSFQVTRAAWEHMKKQKYGRIIMTS 150



 Score = 60.5 bits (140), Expect = 3e-09
 Identities = 25/49 (51%), Positives = 37/49 (75%)
 Frame = +2

Query: 233 GGEANKNAIDNFGRIDILINNAGILRDKSXTKMTXXDXDLIQXVHLKGA 379
           G +  K A+D FGRID+++NNAGILRD+S  +++  D D+I  VHL+G+
Sbjct: 79  GEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRVHLRGS 127


>AF057740-1|AAD08652.1|  736|Homo sapiens 17-beta-hydroxysteroid
           dehydrogenase IV protein.
          Length = 736

 Score = 75.8 bits (178), Expect = 6e-14
 Identities = 55/146 (37%), Positives = 67/146 (45%), Gaps = 1/146 (0%)
 Frame = +3

Query: 15  LRFDGRVAVVTXXXXXXXXXXXXXXXSRGAKVVVNDLGSARDGAGK-SNAADAVVKEIKD 191
           LRFDGRV +VT                RGA VVVNDLG    G GK S AAD VV+EI+ 
Sbjct: 5   LRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEIRR 64

Query: 192 KGGVAVADYNSVVEGEXXXXXXXXXXXXXXFLSTMLAFSVIRAXLK*LXXTXT*FSXSI* 371
           +GG AVA+Y+SV EGE               +         R+  +              
Sbjct: 65  RGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRVHL 124

Query: 372 KVLFKTTYAAWXTFILLKYGRIVMTS 449
           +  F+ T AAW      KYGRI+MTS
Sbjct: 125 RGSFQVTRAAWEHMKKQKYGRIIMTS 150



 Score = 60.5 bits (140), Expect = 3e-09
 Identities = 25/49 (51%), Positives = 37/49 (75%)
 Frame = +2

Query: 233 GGEANKNAIDNFGRIDILINNAGILRDKSXTKMTXXDXDLIQXVHLKGA 379
           G +  K A+D FGRID+++NNAGILRD+S  +++  D D+I  VHL+G+
Sbjct: 79  GEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRVHLRGS 127


>U63296-1|AAB53034.1|  143|Homo sapiens 15-hydroxyprostaglandin
           dehydrogenase protein.
          Length = 143

 Score = 36.7 bits (81), Expect = 0.037
 Identities = 13/27 (48%), Positives = 21/27 (77%)
 Frame = +2

Query: 248 KNAIDNFGRIDILINNAGILRDKSXTK 328
           +  +D+FGR+DIL+NNAG+  +K+  K
Sbjct: 76  RKVVDHFGRLDILVNNAGVNNEKNWEK 102


>L76465-1|AAA89175.1|  266|Homo sapiens NAD+-dependent
           15-hydroxyprostaglandin dehydrogenase protein.
          Length = 266

 Score = 36.7 bits (81), Expect = 0.037
 Identities = 13/27 (48%), Positives = 21/27 (77%)
 Frame = +2

Query: 248 KNAIDNFGRIDILINNAGILRDKSXTK 328
           +  +D+FGR+DIL+NNAG+  +K+  K
Sbjct: 76  RKVVDHFGRLDILVNNAGVNNEKNWEK 102


>J05594-1|AAA89174.1|  266|Homo sapiens NAD+-dependent
           15-hydroxyprostaglandin dehydrogenase protein.
          Length = 266

 Score = 36.7 bits (81), Expect = 0.037
 Identities = 13/27 (48%), Positives = 21/27 (77%)
 Frame = +2

Query: 248 KNAIDNFGRIDILINNAGILRDKSXTK 328
           +  +D+FGR+DIL+NNAG+  +K+  K
Sbjct: 76  RKVVDHFGRLDILVNNAGVNNEKNWEK 102


>DQ903072-1|ABI75347.1|  266|Homo sapiens hydroxyprostaglandin
           dehydrogenase 15-(NAD) protein.
          Length = 266

 Score = 36.7 bits (81), Expect = 0.037
 Identities = 13/27 (48%), Positives = 21/27 (77%)
 Frame = +2

Query: 248 KNAIDNFGRIDILINNAGILRDKSXTK 328
           +  +D+FGR+DIL+NNAG+  +K+  K
Sbjct: 76  RKVVDHFGRLDILVNNAGVNNEKNWEK 102


>BC018986-1|AAH18986.1|  266|Homo sapiens hydroxyprostaglandin
           dehydrogenase 15-(NAD) protein.
          Length = 266

 Score = 36.7 bits (81), Expect = 0.037
 Identities = 13/27 (48%), Positives = 21/27 (77%)
 Frame = +2

Query: 248 KNAIDNFGRIDILINNAGILRDKSXTK 328
           +  +D+FGR+DIL+NNAG+  +K+  K
Sbjct: 76  RKVVDHFGRLDILVNNAGVNNEKNWEK 102


>X82460-1|CAA57843.1|  178|Homo sapiens 15-hydroxy prostaglandin
           dehydrogenase protein.
          Length = 178

 Score = 35.5 bits (78), Expect = 0.084
 Identities = 13/27 (48%), Positives = 20/27 (74%)
 Frame = +2

Query: 248 KNAIDNFGRIDILINNAGILRDKSXTK 328
           +  +D+FGR+DIL+NNAG+   K+  K
Sbjct: 76  RKVVDHFGRLDILVNNAGVNNKKNWEK 102


>BC007337-1|AAH07337.1|  339|Homo sapiens dehydrogenase/reductase
           (SDR family) member 7 protein.
          Length = 339

 Score = 30.7 bits (66), Expect = 2.4
 Identities = 12/21 (57%), Positives = 15/21 (71%)
 Frame = +2

Query: 242 ANKNAIDNFGRIDILINNAGI 304
           A K  +  FGRIDIL+NN G+
Sbjct: 121 ATKAVLQEFGRIDILVNNGGM 141


>BC000637-1|AAH00637.1|  339|Homo sapiens dehydrogenase/reductase
           (SDR family) member 7 protein.
          Length = 339

 Score = 30.7 bits (66), Expect = 2.4
 Identities = 12/21 (57%), Positives = 15/21 (71%)
 Frame = +2

Query: 242 ANKNAIDNFGRIDILINNAGI 304
           A K  +  FGRIDIL+NN G+
Sbjct: 121 ATKAVLQEFGRIDILVNNGGM 141


>AY359031-1|AAQ89390.1|  289|Homo sapiens oxidoreductase/S-2 H
           protein.
          Length = 289

 Score = 30.7 bits (66), Expect = 2.4
 Identities = 12/21 (57%), Positives = 15/21 (71%)
 Frame = +2

Query: 242 ANKNAIDNFGRIDILINNAGI 304
           A K  +  FGRIDIL+NN G+
Sbjct: 71  ATKAVLQEFGRIDILVNNGGM 91


>AF151844-1|AAD34081.1|  339|Homo sapiens CGI-86 protein protein.
          Length = 339

 Score = 30.7 bits (66), Expect = 2.4
 Identities = 12/21 (57%), Positives = 15/21 (71%)
 Frame = +2

Query: 242 ANKNAIDNFGRIDILINNAGI 304
           A K  +  FGRIDIL+NN G+
Sbjct: 121 ATKAVLQEFGRIDILVNNGGM 141


>AF126782-1|AAF06941.1|  289|Homo sapiens retinal short-chain
           dehydrogenase/reductase retSDR4 protein.
          Length = 289

 Score = 30.7 bits (66), Expect = 2.4
 Identities = 12/21 (57%), Positives = 15/21 (71%)
 Frame = +2

Query: 242 ANKNAIDNFGRIDILINNAGI 304
           A K  +  FGRIDIL+NN G+
Sbjct: 71  ATKAVLQEFGRIDILVNNGGM 91


>BC095451-1|AAH95451.1|  418|Homo sapiens hydroxysteroid
           dehydrogenase like 2 protein.
          Length = 418

 Score = 29.9 bits (64), Expect = 4.2
 Identities = 16/45 (35%), Positives = 23/45 (51%)
 Frame = +2

Query: 242 ANKNAIDNFGRIDILINNAGILRDKSXTKMTXXDXDLIQXVHLKG 376
           A + AI  FG IDIL+NNA  +   +         DL+  V+ +G
Sbjct: 84  AVEKAIKKFGGIDILVNNASAISLTNTLDTPTKRLDLMMNVNTRG 128


>AY093428-1|AAM14670.1|  418|Homo sapiens hydroxysteroid
           dehydrogenase-like protein protein.
          Length = 418

 Score = 29.9 bits (64), Expect = 4.2
 Identities = 16/45 (35%), Positives = 23/45 (51%)
 Frame = +2

Query: 242 ANKNAIDNFGRIDILINNAGILRDKSXTKMTXXDXDLIQXVHLKG 376
           A + AI  FG IDIL+NNA  +   +         DL+  V+ +G
Sbjct: 84  AVEKAIKKFGGIDILVNNASAISLTNTLDTPTKRLDLMMNVNTRG 128


>AL162732-1|CAM17152.1|  418|Homo sapiens hydroxysteroid
           dehydrogenase like 2 protein.
          Length = 418

 Score = 29.9 bits (64), Expect = 4.2
 Identities = 16/45 (35%), Positives = 23/45 (51%)
 Frame = +2

Query: 242 ANKNAIDNFGRIDILINNAGILRDKSXTKMTXXDXDLIQXVHLKG 376
           A + AI  FG IDIL+NNA  +   +         DL+  V+ +G
Sbjct: 84  AVEKAIKKFGGIDILVNNASAISLTNTLDTPTKRLDLMMNVNTRG 128


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 46,612,730
Number of Sequences: 237096
Number of extensions: 722125
Number of successful extensions: 1842
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 1747
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1839
length of database: 76,859,062
effective HSP length: 84
effective length of database: 56,942,998
effective search space used: 3701294870
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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