Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= br--0251
(666 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI00015B4F49 Cluster: PREDICTED: similar to lipoic aci... 127 2e-28
UniRef50_A6QV10 Cluster: Lipoic acid synthetase, mitochondrial; ... 112 8e-24
UniRef50_Q7RBD6 Cluster: Lipoic acid synthetase, putative; n=8; ... 106 4e-22
UniRef50_O43766 Cluster: Lipoic acid synthetase, mitochondrial p... 105 1e-21
UniRef50_Q9Y9E3 Cluster: Probable lipoyl synthase; n=4; cellular... 104 2e-21
UniRef50_Q8LSZ8 Cluster: Lipoic acid synthase; n=7; cellular org... 102 7e-21
UniRef50_A5E450 Cluster: Lipoic acid synthetase, mitochondrial; ... 98 2e-19
UniRef50_P32875 Cluster: Lipoic acid synthetase, mitochondrial p... 97 4e-19
UniRef50_Q8ZUR9 Cluster: Probable lipoyl synthase; n=4; cellular... 94 2e-18
UniRef50_Q01AS9 Cluster: Lipoic acid synthase; n=1; Ostreococcus... 93 5e-18
UniRef50_Q4JBV4 Cluster: Probable lipoyl synthase; n=4; cellular... 90 4e-17
UniRef50_Q9RWA4 Cluster: Lipoyl synthase; n=33; cellular organis... 89 7e-17
UniRef50_Q0W150 Cluster: Putative lipoate synthetase; n=1; uncul... 85 1e-15
UniRef50_Q4QDI6 Cluster: Lipoic acid synthetase, mitochondrial, ... 85 2e-15
UniRef50_Q8R9E1 Cluster: Lipoyl synthase; n=31; cellular organis... 72 1e-11
UniRef50_Q821K6 Cluster: Lipoyl synthase; n=4; Chlamydiaceae|Rep... 69 8e-11
UniRef50_Q028Q9 Cluster: Lipoic acid synthetase precursor; n=2; ... 69 1e-10
UniRef50_A1HSS2 Cluster: Lipoic acid synthetase; n=2; Bacteria|R... 68 2e-10
UniRef50_Q9PJI2 Cluster: Lipoyl synthase; n=4; Chlamydiales|Rep:... 66 7e-10
UniRef50_O67368 Cluster: Lipoyl synthase; n=1; Aquifex aeolicus|... 66 7e-10
UniRef50_Q4UK97 Cluster: Lipoyl synthase; n=131; Bacteria|Rep: L... 65 1e-09
UniRef50_Q7UH37 Cluster: Lipoyl synthase; n=3; Planctomycetaceae... 65 1e-09
UniRef50_Q8ERL8 Cluster: Lipoyl synthase; n=51; Bacteria|Rep: Li... 65 1e-09
UniRef50_P61199 Cluster: Lipoyl synthase; n=4; Bacteria|Rep: Lip... 65 2e-09
UniRef50_Q7VKB1 Cluster: Lipoyl synthase; n=9; cellular organism... 64 2e-09
UniRef50_Q3ARP5 Cluster: Lipoate synthase; n=11; Bacteria|Rep: L... 63 5e-09
UniRef50_P61196 Cluster: Lipoyl synthase; n=7; Bacteria|Rep: Lip... 63 5e-09
UniRef50_Q9PDW0 Cluster: Lipoyl synthase; n=257; Bacteria|Rep: L... 62 9e-09
UniRef50_A6DU97 Cluster: Lipoyl synthase; n=1; Lentisphaera aran... 61 2e-08
UniRef50_A6GIK5 Cluster: Lipoyl synthase; n=2; Bacteria|Rep: Lip... 60 5e-08
UniRef50_Q8YWC1 Cluster: Lipoyl synthase 1; n=18; Cyanobacteria|... 60 5e-08
UniRef50_Q8DL83 Cluster: Lipoyl synthase 2; n=7; Bacteria|Rep: L... 59 8e-08
UniRef50_Q0LDD9 Cluster: Lipoic acid synthetase; n=1; Herpetosip... 59 1e-07
UniRef50_A5MZI9 Cluster: LipA2; n=1; Clostridium kluyveri DSM 55... 58 2e-07
UniRef50_P61194 Cluster: Lipoyl synthase; n=54; Bacteria|Rep: Li... 57 4e-07
UniRef50_Q8F3V7 Cluster: Lipoyl synthase; n=4; Leptospira|Rep: L... 56 6e-07
UniRef50_A6Q3H7 Cluster: Lipoate synthase; n=1; Nitratiruptor sp... 54 2e-06
UniRef50_Q7VBJ3 Cluster: Lipoyl synthase 2; n=37; Cyanobacteria|... 50 4e-05
UniRef50_Q3ERB0 Cluster: Lipoic acid synthetase; n=1; Bacillus t... 47 4e-04
UniRef50_A3UCG7 Cluster: Possible NADPH-dependent oxidoreductase... 34 2.7
UniRef50_UPI0000E8100B Cluster: PREDICTED: hypothetical protein;... 33 6.2
UniRef50_Q90744 Cluster: Alpha-N-acetylgalactosaminidase; n=18; ... 33 6.2
UniRef50_UPI0000E8019D Cluster: PREDICTED: hypothetical protein;... 33 8.2
UniRef50_Q3KBV9 Cluster: PilL protein precursor; n=1; Pseudomona... 33 8.2
UniRef50_Q22XZ7 Cluster: Protein kinase domain containing protei... 33 8.2
UniRef50_A5DNV7 Cluster: Putative uncharacterized protein; n=1; ... 33 8.2
UniRef50_P55687 Cluster: Uncharacterized protein y4wI; n=6; Rhiz... 33 8.2
>UniRef50_UPI00015B4F49 Cluster: PREDICTED: similar to lipoic acid
synthetase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to lipoic acid synthetase - Nasonia vitripennis
Length = 648
Score = 127 bits (307), Expect = 2e-28
Identities = 75/167 (44%), Positives = 98/167 (58%), Gaps = 2/167 (1%)
Frame = +2
Query: 14 DILVECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPRAGYRQTLKVLQMA 193
+ILVECLVPDF+ V V SGLDV+AHN+ETVERLTPFVRD RA Y+Q+L +L A
Sbjct: 477 NILVECLVPDFQGNLDSVKTVVESGLDVYAHNIETVERLTPFVRDRRARYKQSLSMLGGA 536
Query: 194 KEINPDLITKSSIMLGLGETARKWSRP*K-IYARREWTA*RWAXXXXXXXXXXXXXXXXX 370
K++NPDLITKSSIMLGLGET + + K + A
Sbjct: 537 KKVNPDLITKSSIMLGLGETDDEVMQTMKDLRAAGVEALTLGQYMQPTKRHLKVIEYVTP 596
Query: 371 XXVQQWEARGRSSASV-RGQRSLVRSSYRAGEFFISAXLRDKKVTRN 508
+ WE G+ + LVRSSY+AGE+F++ L++K+ +N
Sbjct: 597 EKFKYWEKVGQELGFLYTASGPLVRSSYKAGEYFLTNILKEKRGEKN 643
Score = 68.5 bits (160), Expect = 1e-10
Identities = 30/38 (78%), Positives = 34/38 (89%)
Frame = +1
Query: 259 QVEQTMKDLREAGVDCVTLGQYMQPTKKHLKVFEYVTP 372
+V QTMKDLR AGV+ +TLGQYMQPTK+HLKV EYVTP
Sbjct: 559 EVMQTMKDLRAAGVEALTLGQYMQPTKRHLKVIEYVTP 596
>UniRef50_A6QV10 Cluster: Lipoic acid synthetase, mitochondrial;
n=1; Ajellomyces capsulatus NAm1|Rep: Lipoic acid
synthetase, mitochondrial - Ajellomyces capsulatus NAm1
Length = 465
Score = 112 bits (269), Expect = 8e-24
Identities = 70/163 (42%), Positives = 88/163 (53%), Gaps = 2/163 (1%)
Frame = +2
Query: 14 DILVECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPRAGYRQTLKVLQMA 193
+ILVECL D+ VA VA+SGLDVFAHNVETVE LTPFVRD RA ++Q+L+VL+ A
Sbjct: 173 NILVECLTGDYAGDLDMVALVANSGLDVFAHNVETVEALTPFVRDRRASFQQSLRVLKAA 232
Query: 194 KEINPDLITKSSIMLGLGET-ARKWSRP*KIYARREWTA*RWAXXXXXXXXXXXXXXXXX 370
K P+LITK+S MLGLGET A+ W + A
Sbjct: 233 KAAKPELITKTSFMLGLGETEAQLWDALRALRAINVDVVTFGQYMRPTKRHMAVHEYVRP 292
Query: 371 XXVQQWEARGRSSASVR-GQRSLVRSSYRAGEFFISAXLRDKK 496
W+ R + LVRSSY+AGE FI L+ ++
Sbjct: 293 DVFDLWKERALEMGFLYCASGPLVRSSYKAGEAFIENVLKKRR 335
Score = 49.6 bits (113), Expect = 7e-05
Identities = 22/45 (48%), Positives = 28/45 (62%)
Frame = +1
Query: 238 GTRRDRAQVEQTMKDLREAGVDCVTLGQYMQPTKKHLKVFEYVTP 372
G AQ+ ++ LR VD VT GQYM+PTK+H+ V EYV P
Sbjct: 248 GLGETEAQLWDALRALRAINVDVVTFGQYMRPTKRHMAVHEYVRP 292
>UniRef50_Q7RBD6 Cluster: Lipoic acid synthetase, putative; n=8;
cellular organisms|Rep: Lipoic acid synthetase, putative
- Plasmodium yoelii yoelii
Length = 502
Score = 106 bits (255), Expect = 4e-22
Identities = 51/79 (64%), Positives = 63/79 (79%)
Frame = +2
Query: 17 ILVECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPRAGYRQTLKVLQMAK 196
IL+ECLV DF+ + R+A SGLDV+AHN+ETV+RL +VRD RA Y Q+L VL+ AK
Sbjct: 288 ILIECLVSDFQGNIDSIKRLALSGLDVYAHNIETVKRLQKYVRDKRANYEQSLYVLKKAK 347
Query: 197 EINPDLITKSSIMLGLGET 253
EINP+L TK+SIMLGLGET
Sbjct: 348 EINPNLYTKTSIMLGLGET 366
Score = 53.6 bits (123), Expect = 4e-06
Identities = 22/45 (48%), Positives = 30/45 (66%)
Frame = +1
Query: 238 GTRRDRAQVEQTMKDLREAGVDCVTLGQYMQPTKKHLKVFEYVTP 372
G + +V QTMKD R +D +T GQY++PTK HL V EY++P
Sbjct: 362 GLGETQDEVLQTMKDARSNDIDVITFGQYLRPTKNHLNVVEYISP 406
>UniRef50_O43766 Cluster: Lipoic acid synthetase, mitochondrial
precursor; n=41; cellular organisms|Rep: Lipoic acid
synthetase, mitochondrial precursor - Homo sapiens
(Human)
Length = 372
Score = 105 bits (251), Expect = 1e-21
Identities = 64/162 (39%), Positives = 83/162 (51%), Gaps = 2/162 (1%)
Frame = +2
Query: 17 ILVECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPRAGYRQTLKVLQMAK 196
ILVECL PDFR + +VA SGLDV+AHNVETV L VRDPR + Q+L+VL+ AK
Sbjct: 207 ILVECLTPDFRGDLKAIEKVALSGLDVYAHNVETVPELQSKVRDPRVNFDQSLRVLKHAK 266
Query: 197 EINPDLITKSSIMLGLGETARKWSRP*KIYARREWTA*RWA-XXXXXXXXXXXXXXXXXX 373
++ PD+I+K+SIMLGLGE + K +
Sbjct: 267 KVQPDVISKTSIMLGLGENDEQVYATMKALREADVDCLTLGQYMQPTRRHLKVEEYITPE 326
Query: 374 XVQQWEARGRS-SASVRGQRSLVRSSYRAGEFFISAXLRDKK 496
+ WE G LVRSSY+AGEFF+ + +K
Sbjct: 327 KFKYWEKVGNELGFHYTASGPLVRSSYKAGEFFLKNLVAKRK 368
Score = 66.5 bits (155), Expect = 5e-10
Identities = 30/45 (66%), Positives = 35/45 (77%)
Frame = +1
Query: 238 GTRRDRAQVEQTMKDLREAGVDCVTLGQYMQPTKKHLKVFEYVTP 372
G + QV TMK LREA VDC+TLGQYMQPT++HLKV EY+TP
Sbjct: 281 GLGENDEQVYATMKALREADVDCLTLGQYMQPTRRHLKVEEYITP 325
>UniRef50_Q9Y9E3 Cluster: Probable lipoyl synthase; n=4; cellular
organisms|Rep: Probable lipoyl synthase - Aeropyrum
pernix
Length = 293
Score = 104 bits (250), Expect = 2e-21
Identities = 52/83 (62%), Positives = 66/83 (79%)
Frame = +2
Query: 2 KLXLDILVECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPRAGYRQTLKV 181
+L D +VE L+PDF+ V V VA+SGL+V AHN+ETVERLTP VRD RAGYRQ+L+V
Sbjct: 122 RLRPDTIVEALIPDFQGVEEHVRLVAASGLEVLAHNIETVERLTPLVRDRRAGYRQSLRV 181
Query: 182 LQMAKEINPDLITKSSIMLGLGE 250
L++AKE ++TKSSI+LGLGE
Sbjct: 182 LEIAKE--EGVVTKSSILLGLGE 202
Score = 41.5 bits (93), Expect = 0.018
Identities = 17/39 (43%), Positives = 26/39 (66%)
Frame = +1
Query: 238 GTRRDRAQVEQTMKDLREAGVDCVTLGQYMQPTKKHLKV 354
G D+++V + M+DLR GVD + L QY +P++K L V
Sbjct: 199 GLGEDKSEVIEAMRDLRSVGVDILVLSQYYRPSRKQLPV 237
>UniRef50_Q8LSZ8 Cluster: Lipoic acid synthase; n=7; cellular
organisms|Rep: Lipoic acid synthase - Arabidopsis
thaliana (Mouse-ear cress)
Length = 394
Score = 102 bits (245), Expect = 7e-21
Identities = 50/80 (62%), Positives = 59/80 (73%)
Frame = +2
Query: 14 DILVECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPRAGYRQTLKVLQMA 193
DI++ECL DFR V + SGLDVFAHNVETV+RL VRDPRAGY Q++ VL+ A
Sbjct: 227 DIMIECLTSDFRGDLEAVDTLVHSGLDVFAHNVETVKRLQRLVRDPRAGYEQSMSVLKHA 286
Query: 194 KEINPDLITKSSIMLGLGET 253
K P +ITK+SIMLGLGET
Sbjct: 287 KISKPGMITKTSIMLGLGET 306
Score = 50.4 bits (115), Expect = 4e-05
Identities = 22/38 (57%), Positives = 28/38 (73%)
Frame = +1
Query: 259 QVEQTMKDLREAGVDCVTLGQYMQPTKKHLKVFEYVTP 372
++++ M DLR VD +TLGQY+QPT HL V EYVTP
Sbjct: 309 ELKEAMADLRAIDVDILTLGQYLQPTPLHLTVKEYVTP 346
>UniRef50_A5E450 Cluster: Lipoic acid synthetase, mitochondrial;
n=4; Fungi/Metazoa group|Rep: Lipoic acid synthetase,
mitochondrial - Lodderomyces elongisporus (Yeast)
(Saccharomyces elongisporus)
Length = 432
Score = 97.9 bits (233), Expect = 2e-19
Identities = 50/79 (63%), Positives = 59/79 (74%)
Frame = +2
Query: 17 ILVECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPRAGYRQTLKVLQMAK 196
ILVE L DFR V +A+SGLDV+AHN+ETVE LTP +RD RA YRQ+L VL+ AK
Sbjct: 250 ILVEVLGGDFRGDLEMVKILANSGLDVYAHNMETVEALTPHIRDRRATYRQSLAVLRTAK 309
Query: 197 EINPDLITKSSIMLGLGET 253
E P LITK+S+MLG GET
Sbjct: 310 ETKPSLITKTSLMLGFGET 328
Score = 65.7 bits (153), Expect = 9e-10
Identities = 27/38 (71%), Positives = 32/38 (84%)
Frame = +1
Query: 259 QVEQTMKDLREAGVDCVTLGQYMQPTKKHLKVFEYVTP 372
Q+ QT+KDLRE G D VT GQYM+PTK+H+KV EYVTP
Sbjct: 331 QIRQTLKDLREVGCDVVTFGQYMRPTKRHMKVVEYVTP 368
>UniRef50_P32875 Cluster: Lipoic acid synthetase, mitochondrial
precursor; n=42; Eukaryota|Rep: Lipoic acid synthetase,
mitochondrial precursor - Saccharomyces cerevisiae
(Baker's yeast)
Length = 414
Score = 96.7 bits (230), Expect = 4e-19
Identities = 65/162 (40%), Positives = 82/162 (50%), Gaps = 2/162 (1%)
Frame = +2
Query: 20 LVECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPRAGYRQTLKVLQMAKE 199
LVE L DFR V +A GLDV+AHN+ETVE LTP VRD RA YRQ+L VL+ AK
Sbjct: 252 LVETLSGDFRGDLKMVDIMAQCGLDVYAHNLETVESLTPHVRDRRATYRQSLSVLERAKA 311
Query: 200 INPDLITKSSIMLGLGETARKWSRP*KIYARREWTA*RWA-XXXXXXXXXXXXXXXXXXX 376
P LITK+SIMLGLGET + ++ K + +
Sbjct: 312 TVPSLITKTSIMLGLGETDEQITQTLKDLRNIQCDVVTFGQYMRPTKRHMKVVEYVKPEK 371
Query: 377 VQQWEARGRSSASVR-GQRSLVRSSYRAGEFFISAXLRDKKV 499
W+ R + LVRSSY+AGE FI L+ + +
Sbjct: 372 FDYWKERALEMGFLYCASGPLVRSSYKAGEAFIENVLKKRNM 413
Score = 57.2 bits (132), Expect = 3e-07
Identities = 24/38 (63%), Positives = 29/38 (76%)
Frame = +1
Query: 259 QVEQTMKDLREAGVDCVTLGQYMQPTKKHLKVFEYVTP 372
Q+ QT+KDLR D VT GQYM+PTK+H+KV EYV P
Sbjct: 332 QITQTLKDLRNIQCDVVTFGQYMRPTKRHMKVVEYVKP 369
>UniRef50_Q8ZUR9 Cluster: Probable lipoyl synthase; n=4; cellular
organisms|Rep: Probable lipoyl synthase - Pyrobaculum
aerophilum
Length = 290
Score = 94.3 bits (224), Expect = 2e-18
Identities = 50/78 (64%), Positives = 55/78 (70%)
Frame = +2
Query: 20 LVECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPRAGYRQTLKVLQMAKE 199
+VE LVPDF V V SSG DVFAHNVETV RLTP VRD RAGY ++L VL+ AKE
Sbjct: 127 VVEVLVPDFGGSPASVKTVVSSGPDVFAHNVETVRRLTPLVRDRRAGYERSLSVLKYAKE 186
Query: 200 INPDLITKSSIMLGLGET 253
L TKS +MLGLGET
Sbjct: 187 FGAPL-TKSGLMLGLGET 203
Score = 42.7 bits (96), Expect = 0.008
Identities = 19/40 (47%), Positives = 28/40 (70%), Gaps = 2/40 (5%)
Frame = +1
Query: 259 QVEQTMKDLREAGVDCVTLGQYMQP--TKKHLKVFEYVTP 372
+V +T++DLR A VD VT+GQY++P + +HL Y TP
Sbjct: 206 EVVETLEDLRRADVDIVTIGQYIKPSGSPRHLNPVRYATP 245
>UniRef50_Q01AS9 Cluster: Lipoic acid synthase; n=1; Ostreococcus
tauri|Rep: Lipoic acid synthase - Ostreococcus tauri
Length = 360
Score = 93.1 bits (221), Expect = 5e-18
Identities = 47/70 (67%), Positives = 53/70 (75%)
Frame = +2
Query: 44 FRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPRAGYRQTLKVLQMAKEINPDLITK 223
F+ VA +A SGLDVFAHNVETVERL VRDPRAGY Q+L VL+ AKE L+TK
Sbjct: 15 FQGDMDAVAHLARSGLDVFAHNVETVERLQKRVRDPRAGYEQSLSVLRHAKESKEGLVTK 74
Query: 224 SSIMLGLGET 253
+SIMLGLGET
Sbjct: 75 TSIMLGLGET 84
Score = 52.8 bits (121), Expect = 7e-06
Identities = 25/75 (33%), Positives = 40/75 (53%)
Frame = +1
Query: 148 PQGGVPPNVESFTNGQRNKS*FNNEVVHHAGTRRDRAQVEQTMKDLREAGVDCVTLGQYM 327
P+ G ++ + + +K + G ++++ M+ +EAGVD TLGQY+
Sbjct: 50 PRAGYEQSLSVLRHAKESKEGLVTKTSIMLGLGETDDEIKECMRACKEAGVDIFTLGQYL 109
Query: 328 QPTKKHLKVFEYVTP 372
QPT HL V E+VTP
Sbjct: 110 QPTSNHLPVSEFVTP 124
>UniRef50_Q4JBV4 Cluster: Probable lipoyl synthase; n=4; cellular
organisms|Rep: Probable lipoyl synthase - Sulfolobus
acidocaldarius
Length = 286
Score = 90.2 bits (214), Expect = 4e-17
Identities = 45/80 (56%), Positives = 56/80 (70%)
Frame = +2
Query: 14 DILVECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPRAGYRQTLKVLQMA 193
D++VE L PDF + V +V SG+DVFAHNVETV LTP VRD RA Y Q+L+VL A
Sbjct: 123 DVIVEVLTPDFMGNKELVEKVIGSGVDVFAHNVETVRSLTPLVRDARASYEQSLRVLSYA 182
Query: 194 KEINPDLITKSSIMLGLGET 253
K + + KSSI+LGLGE+
Sbjct: 183 KNV----VKKSSILLGLGES 198
Score = 41.9 bits (94), Expect = 0.013
Identities = 28/85 (32%), Positives = 42/85 (49%), Gaps = 1/85 (1%)
Frame = +1
Query: 259 QVEQTMKDLREAGVDCVTLGQYMQPTKKHLKVFE-YVTPAGSAVGGARPQLGFCTWPAEP 435
+V +TMKDLR GVD + L QYM+P+ K L+V + Y + LGF A P
Sbjct: 201 EVVETMKDLRNVGVDILVLSQYMRPSIKQLEVKKRYNMEEYKELEKIAYSLGFSYVVALP 260
Query: 436 GALVLQGRRVLHQRRAAGQEGNSQY 510
A + + R A + N+++
Sbjct: 261 HARTSYRAKEAYLRAMANVKNNNRW 285
>UniRef50_Q9RWA4 Cluster: Lipoyl synthase; n=33; cellular
organisms|Rep: Lipoyl synthase - Deinococcus radiodurans
Length = 331
Score = 89.4 bits (212), Expect = 7e-17
Identities = 45/77 (58%), Positives = 53/77 (68%)
Frame = +2
Query: 23 VECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPRAGYRQTLKVLQMAKEI 202
VE L PDF CV V SG+D +A N+ETV RLT VRD RA Y +TL VL AK+
Sbjct: 158 VEALTPDFGGNTACVDLVLDSGVDTYAQNLETVRRLTHPVRDIRASYDRTLSVLAHAKQA 217
Query: 203 NPDLITKSSIMLGLGET 253
PD+ITK+S+MLGLGET
Sbjct: 218 RPDVITKTSLMLGLGET 234
Score = 51.2 bits (117), Expect = 2e-05
Identities = 25/60 (41%), Positives = 34/60 (56%), Gaps = 1/60 (1%)
Frame = +1
Query: 238 GTRRDRAQVEQTMKDLREAGVDCVTLGQYMQPTKKHLKVFEYVTPAG-SAVGGARPQLGF 414
G R ++ + M D R AGVD +T GQY++PT HL V Y++PA + QLGF
Sbjct: 230 GLGETREEIREAMADCRAAGVDVLTFGQYLRPTMHHLPVERYISPAEFDEIREEGMQLGF 289
>UniRef50_Q0W150 Cluster: Putative lipoate synthetase; n=1;
uncultured methanogenic archaeon RC-I|Rep: Putative
lipoate synthetase - Uncultured methanogenic archaeon
RC-I
Length = 296
Score = 85.0 bits (201), Expect = 1e-15
Identities = 38/76 (50%), Positives = 55/76 (72%)
Frame = +2
Query: 23 VECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPRAGYRQTLKVLQMAKEI 202
VE ++PDF + +V + DV +HN+ETVERL+P VRD RAGY ++L VL+ K +
Sbjct: 136 VEAIIPDFTGRLDLLEQVVDARPDVISHNIETVERLSPSVRDRRAGYYRSLDVLRDVKRV 195
Query: 203 NPDLITKSSIMLGLGE 250
NP ++TKSS++LG+GE
Sbjct: 196 NPHMLTKSSLLLGMGE 211
Score = 43.2 bits (97), Expect = 0.006
Identities = 18/45 (40%), Positives = 29/45 (64%)
Frame = +1
Query: 238 GTRRDRAQVEQTMKDLREAGVDCVTLGQYMQPTKKHLKVFEYVTP 372
G + ++++ + DL+EA VD VTLGQY++P+ + V YV P
Sbjct: 208 GMGEEDIEIKEALHDLQEARVDIVTLGQYLRPSIRQWPVHRYVAP 252
>UniRef50_Q4QDI6 Cluster: Lipoic acid synthetase, mitochondrial,
putative; n=7; Eukaryota|Rep: Lipoic acid synthetase,
mitochondrial, putative - Leishmania major
Length = 410
Score = 84.6 bits (200), Expect = 2e-15
Identities = 57/166 (34%), Positives = 86/166 (51%), Gaps = 5/166 (3%)
Frame = +2
Query: 14 DILVECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPRAGYRQTLKVLQ-M 190
++++E LV DF V ++A + L V+AHN+E VER+TP VRD RA YRQ+L+ L+ +
Sbjct: 226 ELMLEALVGDFHGDLKLVEQLAVTPLSVYAHNIECVERITPRVRDRRASYRQSLQTLEHV 285
Query: 191 AKEINPDLITKSSIMLGLGE---TARKWSRP*KIYARREWTA*RWAXXXXXXXXXXXXXX 361
K N +++TKSSIMLGLGE R+ R + T ++
Sbjct: 286 TKWTNGNMLTKSSIMLGLGEEEAEVRQTLRDLRTAGVSAVTLGQY--LQPSHTRLKVSRY 343
Query: 362 XXXXXVQQWEARGRSSASVR-GQRSLVRSSYRAGEFFISAXLRDKK 496
+ WE + +VRSSYRAGE++I L+ ++
Sbjct: 344 AHPKEFEMWEKEAMDMGFLYCASGPMVRSSYRAGEYYIKNILKQRQ 389
Score = 54.0 bits (124), Expect = 3e-06
Identities = 24/45 (53%), Positives = 30/45 (66%)
Frame = +1
Query: 238 GTRRDRAQVEQTMKDLREAGVDCVTLGQYMQPTKKHLKVFEYVTP 372
G + A+V QT++DLR AGV VTLGQY+QP+ LKV Y P
Sbjct: 302 GLGEEEAEVRQTLRDLRTAGVSAVTLGQYLQPSHTRLKVSRYAHP 346
>UniRef50_Q8R9E1 Cluster: Lipoyl synthase; n=31; cellular
organisms|Rep: Lipoyl synthase - Thermoanaerobacter
tengcongensis
Length = 284
Score = 72.1 bits (169), Expect = 1e-11
Identities = 38/79 (48%), Positives = 51/79 (64%)
Frame = +2
Query: 17 ILVECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPRAGYRQTLKVLQMAK 196
+ VE LVPDF + V + DV HNVETV RL VR P+A Y ++L +L+ K
Sbjct: 128 VTVEVLVPDFMGNEEAIRTVVEAKPDVINHNVETVPRLYSRVR-PKADYIRSLNLLKKVK 186
Query: 197 EINPDLITKSSIMLGLGET 253
E++P ++TKS IM+GLGET
Sbjct: 187 ELDPLILTKSGIMVGLGET 205
Score = 51.2 bits (117), Expect = 2e-05
Identities = 21/45 (46%), Positives = 31/45 (68%)
Frame = +1
Query: 238 GTRRDRAQVEQTMKDLREAGVDCVTLGQYMQPTKKHLKVFEYVTP 372
G +V + MKDLR+ D +T+GQY++P+ KH++V EYVTP
Sbjct: 201 GLGETEEEVIEVMKDLRDIDCDMMTIGQYLRPSHKHIEVAEYVTP 245
>UniRef50_Q821K6 Cluster: Lipoyl synthase; n=4; Chlamydiaceae|Rep:
Lipoyl synthase - Chlamydophila caviae
Length = 312
Score = 69.3 bits (162), Expect = 8e-11
Identities = 38/76 (50%), Positives = 49/76 (64%)
Frame = +2
Query: 23 VECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPRAGYRQTLKVLQMAKEI 202
VE L DF+ + + SGL ++ HNVETVERLTP VR +A YR++L +L+ A
Sbjct: 149 VEVLASDFQGNIDALHTLLDSGLTIYNHNVETVERLTPVVRH-KATYRRSLFMLEQAAMY 207
Query: 203 NPDLITKSSIMLGLGE 250
PDL KS IM+GLGE
Sbjct: 208 LPDLKIKSGIMVGLGE 223
Score = 52.4 bits (120), Expect = 9e-06
Identities = 21/45 (46%), Positives = 32/45 (71%)
Frame = +1
Query: 238 GTRRDRAQVEQTMKDLREAGVDCVTLGQYMQPTKKHLKVFEYVTP 372
G ++V+QT+KDL + GV VT+GQY++P++ H+ V YVTP
Sbjct: 220 GLGEQESEVKQTLKDLADHGVKIVTIGQYLRPSRSHIPVKSYVTP 264
>UniRef50_Q028Q9 Cluster: Lipoic acid synthetase precursor; n=2;
Bacteria|Rep: Lipoic acid synthetase precursor -
Solibacter usitatus (strain Ellin6076)
Length = 308
Score = 68.5 bits (160), Expect = 1e-10
Identities = 39/78 (50%), Positives = 47/78 (60%)
Frame = +2
Query: 23 VECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPRAGYRQTLKVLQMAKEI 202
VE L PDF VARV +G VF HN+ETV RL VR P+A YRQ+L VL A+
Sbjct: 151 VEVLTPDFCGDLDAVARVLDAGPHVFNHNMETVPRLYARVR-PQAEYRQSLDVLAFARRF 209
Query: 203 NPDLITKSSIMLGLGETA 256
++ KS M+GLGE A
Sbjct: 210 AEGVLVKSGFMVGLGERA 227
Score = 48.4 bits (110), Expect = 2e-04
Identities = 22/45 (48%), Positives = 31/45 (68%)
Frame = +1
Query: 238 GTRRDRAQVEQTMKDLREAGVDCVTLGQYMQPTKKHLKVFEYVTP 372
G R D +VE ++DL EAG T+GQY+QPT+++L V E+V P
Sbjct: 224 GERAD--EVEALLRDLHEAGTQIATIGQYLQPTRRNLPVEEFVEP 266
>UniRef50_A1HSS2 Cluster: Lipoic acid synthetase; n=2; Bacteria|Rep:
Lipoic acid synthetase - Thermosinus carboxydivorans
Nor1
Length = 294
Score = 67.7 bits (158), Expect = 2e-10
Identities = 39/77 (50%), Positives = 49/77 (63%), Gaps = 1/77 (1%)
Frame = +2
Query: 23 VECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPRAGYRQTLKVL-QMAKE 199
VE L PDFR +A V ++G +VFAHNVETV RL VR P A YR+++ +L Q A+
Sbjct: 139 VEVLTPDFRGAPAALATVLAAGPEVFAHNVETVPRLYLAVR-PGAEYRRSVNLLAQAART 197
Query: 200 INPDLITKSSIMLGLGE 250
P K+ IMLGLGE
Sbjct: 198 AKPGTEIKTGIMLGLGE 214
Score = 49.2 bits (112), Expect = 9e-05
Identities = 27/67 (40%), Positives = 37/67 (55%), Gaps = 1/67 (1%)
Frame = +1
Query: 238 GTRRDRAQVEQTMKDLREAGVDCVTLGQYMQPTKKHLKVFEYVTPAGSAV-GGARPQLGF 414
G + A+V ++D+R AGV +TLGQY+ PT +H V YV PA A Q+GF
Sbjct: 211 GLGEEEAEVMAVLEDVRAAGVTMITLGQYLAPTGRHYPVQRYVPPAEFAKWAEVGRQMGF 270
Query: 415 CTWPAEP 435
+ A P
Sbjct: 271 KSVAAGP 277
>UniRef50_Q9PJI2 Cluster: Lipoyl synthase; n=4; Chlamydiales|Rep:
Lipoyl synthase - Chlamydia muridarum
Length = 308
Score = 66.1 bits (154), Expect = 7e-10
Identities = 33/76 (43%), Positives = 49/76 (64%)
Frame = +2
Query: 23 VECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPRAGYRQTLKVLQMAKEI 202
+E L DF + + + + ++ HNVETVERL+P VR +A YR++L +L+ A +
Sbjct: 146 IEVLASDFEGNIDALHHLLDARIAIYNHNVETVERLSPLVRH-KATYRRSLMMLEQAAQY 204
Query: 203 NPDLITKSSIMLGLGE 250
PDL+ KS IM+GLGE
Sbjct: 205 LPDLMIKSGIMVGLGE 220
Score = 51.2 bits (117), Expect = 2e-05
Identities = 19/45 (42%), Positives = 33/45 (73%)
Frame = +1
Query: 238 GTRRDRAQVEQTMKDLREAGVDCVTLGQYMQPTKKHLKVFEYVTP 372
G ++++QT+KDL + GV VT+GQY++P+++H+ V YV+P
Sbjct: 217 GLGEQESEIKQTLKDLADHGVKIVTIGQYLRPSRRHIPVKSYVSP 261
>UniRef50_O67368 Cluster: Lipoyl synthase; n=1; Aquifex
aeolicus|Rep: Lipoyl synthase - Aquifex aeolicus
Length = 276
Score = 66.1 bits (154), Expect = 7e-10
Identities = 36/79 (45%), Positives = 50/79 (63%)
Frame = +2
Query: 14 DILVECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPRAGYRQTLKVLQMA 193
DI VE L+PDFR + + V V HNVETV RL P VR A Y+++L +L+ +
Sbjct: 121 DIKVEVLIPDFRGNKKALEVVLKEKPVVLNHNVETVPRLYPSVR-IGANYKRSLNILKWS 179
Query: 194 KEINPDLITKSSIMLGLGE 250
KEI+ + TKS+++LG GE
Sbjct: 180 KEIDKSVYTKSALILGFGE 198
Score = 36.7 bits (81), Expect = 0.50
Identities = 16/37 (43%), Positives = 23/37 (62%)
Frame = +1
Query: 253 RAQVEQTMKDLREAGVDCVTLGQYMQPTKKHLKVFEY 363
+ +V + M+DLR D + LGQY QP+ KH V +Y
Sbjct: 200 KEEVIKVMEDLRSVDCDFLVLGQYYQPSLKHHPVVKY 236
>UniRef50_Q4UK97 Cluster: Lipoyl synthase; n=131; Bacteria|Rep:
Lipoyl synthase - Rickettsia felis (Rickettsia azadi)
Length = 301
Score = 65.3 bits (152), Expect = 1e-09
Identities = 33/76 (43%), Positives = 47/76 (61%)
Frame = +2
Query: 23 VECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPRAGYRQTLKVLQMAKEI 202
+E L PDF G +A++ DVF HNVETV L +R P A Y +L +L K++
Sbjct: 134 IEILTPDFLRKEGAAEIIANAKPDVFNHNVETVPSLYKTIR-PGARYYNSLSLLHNIKKL 192
Query: 203 NPDLITKSSIMLGLGE 250
+P++ TKS +M+GLGE
Sbjct: 193 SPEIFTKSGMMVGLGE 208
Score = 56.0 bits (129), Expect = 8e-07
Identities = 25/45 (55%), Positives = 33/45 (73%)
Frame = +1
Query: 238 GTRRDRAQVEQTMKDLREAGVDCVTLGQYMQPTKKHLKVFEYVTP 372
G + ++V Q M DLREA VD +T+GQY+QPTK H +V +YVTP
Sbjct: 205 GLGEEISEVIQVMDDLREAKVDFLTIGQYLQPTKNHAEVAKYVTP 249
>UniRef50_Q7UH37 Cluster: Lipoyl synthase; n=3;
Planctomycetaceae|Rep: Lipoyl synthase - Rhodopirellula
baltica
Length = 316
Score = 65.3 bits (152), Expect = 1e-09
Identities = 33/75 (44%), Positives = 47/75 (62%)
Frame = +2
Query: 26 ECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPRAGYRQTLKVLQMAKEIN 205
E L PDF + +ARV + VF HN+ETV RL VR P++ Y TL++++ K +
Sbjct: 164 EVLTPDFVHCKEALARVIEAKPTVFNHNMETVPRLYRRVRGPKSDYAWTLEMMRQVKRYD 223
Query: 206 PDLITKSSIMLGLGE 250
++ TKS +MLGLGE
Sbjct: 224 AEVKTKSGLMLGLGE 238
Score = 47.6 bits (108), Expect = 3e-04
Identities = 21/45 (46%), Positives = 29/45 (64%)
Frame = +1
Query: 238 GTRRDRAQVEQTMKDLREAGVDCVTLGQYMQPTKKHLKVFEYVTP 372
G +R ++ + DLRE VD +TLGQY+QP +K+L V YV P
Sbjct: 235 GLGEERGELLDALSDLREHDVDFLTLGQYLQPGEKYLPVVRYVPP 279
>UniRef50_Q8ERL8 Cluster: Lipoyl synthase; n=51; Bacteria|Rep:
Lipoyl synthase - Oceanobacillus iheyensis
Length = 314
Score = 65.3 bits (152), Expect = 1e-09
Identities = 36/76 (47%), Positives = 49/76 (64%)
Frame = +2
Query: 23 VECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPRAGYRQTLKVLQMAKEI 202
+E L D + + + SG D+F HN+ETV RLT VR RA Y ++L++L+ KEI
Sbjct: 138 IEILPSDMKGDYESLHTLMDSGPDIFNHNIETVRRLTKRVR-ARAMYDRSLELLRRVKEI 196
Query: 203 NPDLITKSSIMLGLGE 250
P+ TKSSIM+GLGE
Sbjct: 197 APNTPTKSSIMVGLGE 212
Score = 51.2 bits (117), Expect = 2e-05
Identities = 23/45 (51%), Positives = 29/45 (64%)
Frame = +1
Query: 238 GTRRDRAQVEQTMKDLREAGVDCVTLGQYMQPTKKHLKVFEYVTP 372
G ++ ++ Q M DL VD VTLGQY+QPTKKHL+V Y P
Sbjct: 209 GLGEEKDEIIQAMDDLLAHNVDIVTLGQYLQPTKKHLEVVRYYHP 253
>UniRef50_P61199 Cluster: Lipoyl synthase; n=4; Bacteria|Rep: Lipoyl
synthase - Treponema denticola
Length = 290
Score = 64.9 bits (151), Expect = 2e-09
Identities = 35/80 (43%), Positives = 51/80 (63%)
Frame = +2
Query: 14 DILVECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPRAGYRQTLKVLQMA 193
++ +E L+PDF+ V+ + + +V +HN+ETV RL+P VR RA Y +LKVL+
Sbjct: 138 NVTMEVLIPDFQGHEDLVSMIIEAKPEVISHNLETVRRLSPHVRS-RATYDTSLKVLKQI 196
Query: 194 KEINPDLITKSSIMLGLGET 253
+ L+ KS IMLGLGET
Sbjct: 197 AD--SGLVCKSGIMLGLGET 214
Score = 45.2 bits (102), Expect = 0.001
Identities = 19/45 (42%), Positives = 31/45 (68%)
Frame = +1
Query: 238 GTRRDRAQVEQTMKDLREAGVDCVTLGQYMQPTKKHLKVFEYVTP 372
G RA++ +TM DLR+ +T+GQY++P+ K+++V EYV P
Sbjct: 210 GLGETRAEILETMDDLRKINCKVMTIGQYLRPSIKNIEVKEYVRP 254
>UniRef50_Q7VKB1 Cluster: Lipoyl synthase; n=9; cellular
organisms|Rep: Lipoyl synthase - Haemophilus ducreyi
Length = 330
Score = 64.5 bits (150), Expect = 2e-09
Identities = 37/78 (47%), Positives = 52/78 (66%), Gaps = 1/78 (1%)
Frame = +2
Query: 23 VECLVPDFRA-VRGCVARVASSGLDVFAHNVETVERLTPFVRDPRAGYRQTLKVLQMAKE 199
VE LVPDFR V VA + + DVF HN+E V RL +R P A Y+ +L++L++ K+
Sbjct: 174 VEILVPDFRGRVEQAVAILKQNPPDVFNHNLENVPRLYREIR-PGADYKWSLELLKIFKQ 232
Query: 200 INPDLITKSSIMLGLGET 253
P++ TKS +M+GLGET
Sbjct: 233 EFPNIPTKSGLMVGLGET 250
Score = 47.6 bits (108), Expect = 3e-04
Identities = 20/46 (43%), Positives = 30/46 (65%)
Frame = +1
Query: 238 GTRRDRAQVEQTMKDLREAGVDCVTLGQYMQPTKKHLKVFEYVTPA 375
G ++ M+DLR+ GV +T+GQY+QP++ HL+V YV PA
Sbjct: 246 GLGETNEEILAVMQDLRDHGVTMLTVGQYLQPSRHHLRVERYVPPA 291
>UniRef50_Q3ARP5 Cluster: Lipoate synthase; n=11; Bacteria|Rep:
Lipoate synthase - Chlorobium chlorochromatii (strain
CaD3)
Length = 300
Score = 63.3 bits (147), Expect = 5e-09
Identities = 33/79 (41%), Positives = 51/79 (64%)
Frame = +2
Query: 14 DILVECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPRAGYRQTLKVLQMA 193
++ +ECL+PDF+ + + V + DV HN+E+V L VR P+A YR +L++L+ A
Sbjct: 140 NVSLECLIPDFQHKKAALDSVMQATPDVLNHNIESVPSLYSTVR-PQANYRASLELLRYA 198
Query: 194 KEINPDLITKSSIMLGLGE 250
KE L TKS +M+G+GE
Sbjct: 199 KE-QHGLATKSGLMVGMGE 216
Score = 49.2 bits (112), Expect = 9e-05
Identities = 22/45 (48%), Positives = 28/45 (62%)
Frame = +1
Query: 238 GTRRDRAQVEQTMKDLREAGVDCVTLGQYMQPTKKHLKVFEYVTP 372
G +R +VE T+ DL G D VT+GQY+QP+ HL V YV P
Sbjct: 213 GMGEERHEVEATLHDLAAHGCDMVTIGQYLQPSAAHLPVARYVPP 257
>UniRef50_P61196 Cluster: Lipoyl synthase; n=7; Bacteria|Rep: Lipoyl
synthase - Geobacter sulfurreducens
Length = 303
Score = 63.3 bits (147), Expect = 5e-09
Identities = 34/78 (43%), Positives = 47/78 (60%)
Frame = +2
Query: 20 LVECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPRAGYRQTLKVLQMAKE 199
+VE L+PDF R +A V ++ + HNVETV RL + A Y ++L VL+ +E
Sbjct: 131 VVELLIPDFLGSRAALADVVAAAPRIIGHNVETVPRL--YAIRAGADYGRSLAVLRTLRE 188
Query: 200 INPDLITKSSIMLGLGET 253
+ P TKS +MLGLGET
Sbjct: 189 LAPGCATKSGLMLGLGET 206
Score = 33.1 bits (72), Expect = 6.2
Identities = 16/45 (35%), Positives = 23/45 (51%)
Frame = +1
Query: 238 GTRRDRAQVEQTMKDLREAGVDCVTLGQYMQPTKKHLKVFEYVTP 372
G +V M DLR ++LGQY+ P++ H V E+V P
Sbjct: 202 GLGETEEEVLAVMADLRRVDCTYLSLGQYLAPSRFHHPVREFVLP 246
>UniRef50_Q9PDW0 Cluster: Lipoyl synthase; n=257; Bacteria|Rep:
Lipoyl synthase - Xylella fastidiosa
Length = 373
Score = 62.5 bits (145), Expect = 9e-09
Identities = 40/81 (49%), Positives = 51/81 (62%), Gaps = 4/81 (4%)
Frame = +2
Query: 23 VECLVPDFRAVRGCVAR----VASSGLDVFAHNVETVERLTPFVRDPRAGYRQTLKVLQM 190
+E L PDFR +G + R +A+ DVF HNVETV L P VR P A Y+ +L +L+
Sbjct: 178 IEILTPDFRG-KGRMDRALDILAACPPDVFNHNVETVPALYPNVR-PGADYQWSLTLLKR 235
Query: 191 AKEINPDLITKSSIMLGLGET 253
K +P + TKS IMLGLGET
Sbjct: 236 FKAQHPQVPTKSGIMLGLGET 256
Score = 49.6 bits (113), Expect = 7e-05
Identities = 31/78 (39%), Positives = 39/78 (50%), Gaps = 1/78 (1%)
Frame = +1
Query: 259 QVEQTMKDLREAGVDCVTLGQYMQPTKKHLKVFEYVTP-AGSAVGGARPQLGFCTWPAEP 435
QV+ T++DLR VD VT+GQY+QPT H V Y TP A+ LGF
Sbjct: 259 QVQATLRDLRAHDVDMVTIGQYLQPTSHHHPVLRYWTPDEYKALEEYGMALGFS--HVAS 316
Query: 436 GALVLQGRRVLHQRRAAG 489
G +V HQ + AG
Sbjct: 317 GPMVRSSYHADHQAKEAG 334
>UniRef50_A6DU97 Cluster: Lipoyl synthase; n=1; Lentisphaera
araneosa HTCC2155|Rep: Lipoyl synthase - Lentisphaera
araneosa HTCC2155
Length = 299
Score = 61.3 bits (142), Expect = 2e-08
Identities = 34/78 (43%), Positives = 49/78 (62%), Gaps = 1/78 (1%)
Frame = +2
Query: 23 VECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPRAGYRQTLKVLQMAKEI 202
+E L PDF + + VF HN+ET ERL+P +R RA Y+++L+VL+ AK
Sbjct: 136 IEVLTPDFNGKEDLIRMTLDAMPTVFNHNLETCERLSPPIRG-RAKYKRSLEVLKNAKAW 194
Query: 203 NP-DLITKSSIMLGLGET 253
+ ++TKS IM+GLGET
Sbjct: 195 SQGKVLTKSGIMVGLGET 212
Score = 45.6 bits (103), Expect = 0.001
Identities = 19/38 (50%), Positives = 27/38 (71%)
Frame = +1
Query: 259 QVEQTMKDLREAGVDCVTLGQYMQPTKKHLKVFEYVTP 372
+V Q + DL EA VD +T+GQY+ P++KH K+ YV P
Sbjct: 215 EVIQCIHDLYEANVDIITIGQYLPPSRKHWKLDRYVRP 252
>UniRef50_A6GIK5 Cluster: Lipoyl synthase; n=2; Bacteria|Rep: Lipoyl
synthase - Plesiocystis pacifica SIR-1
Length = 322
Score = 60.1 bits (139), Expect = 5e-08
Identities = 36/76 (47%), Positives = 49/76 (64%)
Frame = +2
Query: 23 VECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPRAGYRQTLKVLQMAKEI 202
+E LVPDF+ V V ++ DVFAHN+ETV RL+ VR +A Y ++ VL+ A+E
Sbjct: 154 IEVLVPDFKGQLADVDAVLAANPDVFAHNLETVPRLSREVR-VQARYDRSYAVLRHAREA 212
Query: 203 NPDLITKSSIMLGLGE 250
+TK+ IMLGLGE
Sbjct: 213 G--ALTKTGIMLGLGE 226
Score = 44.8 bits (101), Expect = 0.002
Identities = 19/45 (42%), Positives = 29/45 (64%)
Frame = +1
Query: 238 GTRRDRAQVEQTMKDLREAGVDCVTLGQYMQPTKKHLKVFEYVTP 372
G + +V + + +L + G+ +TLGQY+QP+KKHL V YV P
Sbjct: 223 GLGEELDEVREVITELGQLGLTILTLGQYLQPSKKHLPVARYVHP 267
>UniRef50_Q8YWC1 Cluster: Lipoyl synthase 1; n=18;
Cyanobacteria|Rep: Lipoyl synthase 1 - Anabaena sp.
(strain PCC 7120)
Length = 291
Score = 60.1 bits (139), Expect = 5e-08
Identities = 32/77 (41%), Positives = 47/77 (61%)
Frame = +2
Query: 23 VECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPRAGYRQTLKVLQMAKEI 202
+E L+PD + + + +V HN ET+ RL VR P+ Y +TL++LQ +++I
Sbjct: 132 IEVLIPDLCGNWEALRIILQASPEVLNHNTETIPRLYRRVR-PQGNYDRTLELLQRSRQI 190
Query: 203 NPDLITKSSIMLGLGET 253
P L TKS IM+GLGET
Sbjct: 191 APWLYTKSGIMVGLGET 207
Score = 53.2 bits (122), Expect = 5e-06
Identities = 22/45 (48%), Positives = 32/45 (71%)
Frame = +1
Query: 238 GTRRDRAQVEQTMKDLREAGVDCVTLGQYMQPTKKHLKVFEYVTP 372
G A+V Q M+DLR D +T+GQY+QP++KHL+V ++VTP
Sbjct: 203 GLGETNAEVRQVMQDLRAVDCDILTIGQYLQPSQKHLQVNDFVTP 247
>UniRef50_Q8DL83 Cluster: Lipoyl synthase 2; n=7; Bacteria|Rep:
Lipoyl synthase 2 - Synechococcus elongatus
(Thermosynechococcus elongatus)
Length = 298
Score = 59.3 bits (137), Expect = 8e-08
Identities = 30/80 (37%), Positives = 51/80 (63%)
Frame = +2
Query: 23 VECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPRAGYRQTLKVLQMAKEI 202
+E L+PD + ++ ++G +V HN ETV RL VR P+ Y+++L++LQ ++
Sbjct: 132 IEVLIPDLCGNWQALDQILAAGPEVLNHNTETVPRLYRRVR-PQGNYQRSLELLQRVRDR 190
Query: 203 NPDLITKSSIMLGLGETARK 262
P + +KS IM+GLGET+ +
Sbjct: 191 APWIYSKSGIMVGLGETSEE 210
Score = 45.6 bits (103), Expect = 0.001
Identities = 18/38 (47%), Positives = 27/38 (71%)
Frame = +1
Query: 259 QVEQTMKDLREAGVDCVTLGQYMQPTKKHLKVFEYVTP 372
+V M+DLR+ G D +T+GQY+QP+ KHL V ++ P
Sbjct: 210 EVVALMQDLRQVGCDILTIGQYLQPSPKHLAVQAFIPP 247
>UniRef50_Q0LDD9 Cluster: Lipoic acid synthetase; n=1; Herpetosiphon
aurantiacus ATCC 23779|Rep: Lipoic acid synthetase -
Herpetosiphon aurantiacus ATCC 23779
Length = 306
Score = 58.8 bits (136), Expect = 1e-07
Identities = 30/77 (38%), Positives = 45/77 (58%)
Frame = +2
Query: 23 VECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPRAGYRQTLKVLQMAKEI 202
VE L+PDF+ + V + V HN+ETV + VR P+ Y ++L++L ++E
Sbjct: 136 VEVLIPDFKGEAEALKTVLDAEPHVLNHNIETVRSVFKSVR-PQGDYDRSLELLARSREF 194
Query: 203 NPDLITKSSIMLGLGET 253
P + TKS M+GLGET
Sbjct: 195 APQITTKSGFMVGLGET 211
Score = 50.4 bits (115), Expect = 4e-05
Identities = 24/75 (32%), Positives = 37/75 (49%)
Frame = +1
Query: 148 PQGGVPPNVESFTNGQRNKS*FNNEVVHHAGTRRDRAQVEQTMKDLREAGVDCVTLGQYM 327
PQG ++E + + G ++ QTM DL+ GV+ VT+GQY+
Sbjct: 177 PQGDYDRSLELLARSREFAPQITTKSGFMVGLGETTDEIYQTMDDLKHVGVELVTIGQYL 236
Query: 328 QPTKKHLKVFEYVTP 372
QP+ H+ V EY+ P
Sbjct: 237 QPSLNHVAVSEYIPP 251
>UniRef50_A5MZI9 Cluster: LipA2; n=1; Clostridium kluyveri DSM
555|Rep: LipA2 - Clostridium kluyveri DSM 555
Length = 287
Score = 58.0 bits (134), Expect = 2e-07
Identities = 31/77 (40%), Positives = 47/77 (61%)
Frame = +2
Query: 23 VECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPRAGYRQTLKVLQMAKEI 202
+E L+PD R + ++ + D+ HNVETVE L VR P A Y +++++L+ K
Sbjct: 131 IELLIPDLRGNWKSLKKIIDAKPDILNHNVETVEILYGKVR-PTAVYSRSIELLRQVKIF 189
Query: 203 NPDLITKSSIMLGLGET 253
+ + TKS IM+GLGET
Sbjct: 190 DKGVYTKSGIMVGLGET 206
Score = 51.2 bits (117), Expect = 2e-05
Identities = 20/45 (44%), Positives = 30/45 (66%)
Frame = +1
Query: 238 GTRRDRAQVEQTMKDLREAGVDCVTLGQYMQPTKKHLKVFEYVTP 372
G QV + M DL E G D +T+GQY++P+K H+ V+EY++P
Sbjct: 202 GLGETEEQVMKVMDDLLEVGCDIMTIGQYLRPSKSHIPVYEYISP 246
>UniRef50_P61194 Cluster: Lipoyl synthase; n=54; Bacteria|Rep:
Lipoyl synthase - Corynebacterium diphtheriae
Length = 349
Score = 56.8 bits (131), Expect = 4e-07
Identities = 31/77 (40%), Positives = 48/77 (62%)
Frame = +2
Query: 23 VECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPRAGYRQTLKVLQMAKEI 202
VE L PDF + V + +VFAHN+ETV R+ +R P Y ++L V++ A++
Sbjct: 152 VENLTPDFSGKPDLLQEVFEARPEVFAHNLETVPRIFKRIR-PAFRYERSLDVIRQARDF 210
Query: 203 NPDLITKSSIMLGLGET 253
L+TKS+++LG+GET
Sbjct: 211 G--LVTKSNLILGMGET 225
>UniRef50_Q8F3V7 Cluster: Lipoyl synthase; n=4; Leptospira|Rep:
Lipoyl synthase - Leptospira interrogans
Length = 301
Score = 56.4 bits (130), Expect = 6e-07
Identities = 30/80 (37%), Positives = 48/80 (60%)
Frame = +2
Query: 14 DILVECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPRAGYRQTLKVLQMA 193
D +E L+PD + + + + D+F HN+ETV+RL P V P+ Y ++L VL++A
Sbjct: 147 DCKIELLIPDLKVKQEALEIIFECNPDIFNHNLETVKRLFPEVA-PQKRYERSLDVLKIA 205
Query: 194 KEINPDLITKSSIMLGLGET 253
+TKS ++LG+GET
Sbjct: 206 SA--RGFLTKSGLILGMGET 223
Score = 49.6 bits (113), Expect = 7e-05
Identities = 21/38 (55%), Positives = 27/38 (71%)
Frame = +1
Query: 259 QVEQTMKDLREAGVDCVTLGQYMQPTKKHLKVFEYVTP 372
+V++ M+DL GV +TLGQY+QPT HL V EYV P
Sbjct: 226 EVKECMQDLASVGVSLLTLGQYLQPTSTHLPVKEYVVP 263
>UniRef50_A6Q3H7 Cluster: Lipoate synthase; n=1; Nitratiruptor sp.
SB155-2|Rep: Lipoate synthase - Nitratiruptor sp.
(strain SB155-2)
Length = 274
Score = 54.4 bits (125), Expect = 2e-06
Identities = 35/80 (43%), Positives = 48/80 (60%), Gaps = 1/80 (1%)
Frame = +2
Query: 23 VECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPRAG-YRQTLKVLQMAKE 199
VE L PDF+ + V +V + AHN+ETVE L F R AG Y+++L+VL+
Sbjct: 128 VELLTPDFQGNKKAVQKVIDANPYKLAHNIETVEPL--FKRIKSAGSYKRSLEVLE--TY 183
Query: 200 INPDLITKSSIMLGLGETAR 259
+ TKSS+M+GLGET R
Sbjct: 184 TTSGIKTKSSVMVGLGETKR 203
Score = 38.3 bits (85), Expect = 0.16
Identities = 23/62 (37%), Positives = 39/62 (62%)
Frame = +1
Query: 184 TNGQRNKS*FNNEVVHHAGTRRDRAQVEQTMKDLREAGVDCVTLGQYMQPTKKHLKVFEY 363
T+G + KS + +V T+RD + ++ +DL +AGV +T+GQY+QP+ + KV +Y
Sbjct: 185 TSGIKTKS---SVMVGLGETKRD---LIRSFQDLVQAGVSQLTIGQYLQPSSSNAKVQKY 238
Query: 364 VT 369
T
Sbjct: 239 YT 240
>UniRef50_Q7VBJ3 Cluster: Lipoyl synthase 2; n=37;
Cyanobacteria|Rep: Lipoyl synthase 2 - Prochlorococcus
marinus
Length = 308
Score = 50.4 bits (115), Expect = 4e-05
Identities = 26/51 (50%), Positives = 38/51 (74%)
Frame = +2
Query: 98 FAHNVETVERLTPFVRDPRAGYRQTLKVLQMAKEINPDLITKSSIMLGLGE 250
F HN+ETVERL VR A Y ++L++L+ ++EI+ ++ TKS +MLGLGE
Sbjct: 183 FNHNLETVERLQKEVRRG-ATYHRSLELLKASREIDNEIPTKSGLMLGLGE 232
Score = 40.3 bits (90), Expect = 0.041
Identities = 19/45 (42%), Positives = 28/45 (62%)
Frame = +1
Query: 238 GTRRDRAQVEQTMKDLREAGVDCVTLGQYMQPTKKHLKVFEYVTP 372
G R D ++ QT+KDLR VT+GQY++P+ H+ V +Y P
Sbjct: 231 GERSD--EIIQTLKDLRSVNCQQVTIGQYLRPSLAHIPVQKYWLP 273
>UniRef50_Q3ERB0 Cluster: Lipoic acid synthetase; n=1; Bacillus
thuringiensis serovar israelensis ATCC 35646|Rep: Lipoic
acid synthetase - Bacillus thuringiensis serovar
israelensis ATCC 35646
Length = 117
Score = 47.2 bits (107), Expect = 4e-04
Identities = 20/34 (58%), Positives = 25/34 (73%)
Frame = +1
Query: 274 MKDLREAGVDCVTLGQYMQPTKKHLKVFEYVTPA 375
+ DLR VD +TLGQY+QP+KKHL V +Y PA
Sbjct: 4 LDDLRANNVDILTLGQYLQPSKKHLPVIKYYPPA 37
>UniRef50_A3UCG7 Cluster: Possible NADPH-dependent oxidoreductase;
n=2; Rhodobacterales|Rep: Possible NADPH-dependent
oxidoreductase - Oceanicaulis alexandrii HTCC2633
Length = 453
Score = 34.3 bits (75), Expect = 2.7
Identities = 20/73 (27%), Positives = 37/73 (50%), Gaps = 2/73 (2%)
Frame = +1
Query: 268 QTMKDLREAGVDCVTLGQYMQPTKKHLKVF--EYVTPAGSAVGGARPQLGFCTWPAEPGA 441
Q +DL G + ++LGQY+ K + F +Y+ P G+A+ + + +PAE
Sbjct: 139 QAQRDLEAGGFEGLSLGQYLDKLKLG-EAFRTQYLLPMGAAI-WSTSEHAMADYPAETFV 196
Query: 442 LVLQGRRVLHQRR 480
+ R++H +R
Sbjct: 197 QFFKNHRLMHAKR 209
>UniRef50_UPI0000E8100B Cluster: PREDICTED: hypothetical protein;
n=1; Gallus gallus|Rep: PREDICTED: hypothetical protein
- Gallus gallus
Length = 185
Score = 33.1 bits (72), Expect = 6.2
Identities = 18/38 (47%), Positives = 20/38 (52%), Gaps = 1/38 (2%)
Frame = +3
Query: 255 RASGADHERSTRGGSGLRNAGPVHAAH-EEAPQGVRVR 365
R SG D R TRGG G R AGP A + QG + R
Sbjct: 25 RGSGGDSGRETRGGPGRREAGPGGAGRAADGAQGAQRR 62
>UniRef50_Q90744 Cluster: Alpha-N-acetylgalactosaminidase; n=18;
Eumetazoa|Rep: Alpha-N-acetylgalactosaminidase - Gallus
gallus (Chicken)
Length = 405
Score = 33.1 bits (72), Expect = 6.2
Identities = 23/71 (32%), Positives = 34/71 (47%)
Frame = +1
Query: 232 HAGTRRDRAQVEQTMKDLREAGVDCVTLGQYMQPTKKHLKVFEYVTPAGSAVGGARPQLG 411
+ GT DR VEQ + E GVD + L K+ + + + A ++ G RP +
Sbjct: 114 YPGTTLDR--VEQDAQTFAEWGVDMLKLDGCYSSGKEQAQGYPQMARALNSTG--RPIVY 169
Query: 412 FCTWPAEPGAL 444
C+WPA G L
Sbjct: 170 SCSWPAYQGGL 180
>UniRef50_UPI0000E8019D Cluster: PREDICTED: hypothetical protein;
n=1; Gallus gallus|Rep: PREDICTED: hypothetical protein
- Gallus gallus
Length = 135
Score = 32.7 bits (71), Expect = 8.2
Identities = 19/40 (47%), Positives = 22/40 (55%), Gaps = 2/40 (5%)
Frame = +3
Query: 246 ARPRASGADHERSTRGGSGLRN-AGPV-HAAHEEAPQGVR 359
AR +G + R R G G R AGP HAA +E PQG R
Sbjct: 48 ARRTPAGTSNARRPRAGRGARRGAGPAAHAAEKERPQGRR 87
>UniRef50_Q3KBV9 Cluster: PilL protein precursor; n=1; Pseudomonas
fluorescens PfO-1|Rep: PilL protein precursor -
Pseudomonas fluorescens (strain PfO-1)
Length = 180
Score = 32.7 bits (71), Expect = 8.2
Identities = 18/42 (42%), Positives = 24/42 (57%), Gaps = 3/42 (7%)
Frame = -3
Query: 331 AACTGPALRSPLPPRVDL---SWSAPLARGLAESQHDGRLRY 215
+ACT + +PLPP ++ S AP +RG AE H LRY
Sbjct: 15 SACTAQ-IPTPLPPHPEIGSGSNQAPHSRGTAEESHPAELRY 55
>UniRef50_Q22XZ7 Cluster: Protein kinase domain containing protein;
n=1; Tetrahymena thermophila SB210|Rep: Protein kinase
domain containing protein - Tetrahymena thermophila
SB210
Length = 681
Score = 32.7 bits (71), Expect = 8.2
Identities = 16/56 (28%), Positives = 29/56 (51%)
Frame = +1
Query: 193 QRNKS*FNNEVVHHAGTRRDRAQVEQTMKDLREAGVDCVTLGQYMQPTKKHLKVFE 360
+RNKS F VH ++ D + + ++++ R A DC +Y+Q H+ V +
Sbjct: 331 KRNKSNFAPINVHAEESKDDDSGIASSVREKRSASADCDFRNKYLQNQSLHITVLK 386
>UniRef50_A5DNV7 Cluster: Putative uncharacterized protein; n=1;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 403
Score = 32.7 bits (71), Expect = 8.2
Identities = 16/57 (28%), Positives = 31/57 (54%)
Frame = +2
Query: 35 VPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPRAGYRQTLKVLQMAKEIN 205
+PDFR+ +G ++++ SGL+ N + V + F +DP Y K+L +++
Sbjct: 133 IPDFRSFQGIYSQLSRSGLE----NAQQVFHIDRFCKDPTLFYLVAHKILPQGDKVS 185
>UniRef50_P55687 Cluster: Uncharacterized protein y4wI; n=6;
Rhizobiales|Rep: Uncharacterized protein y4wI -
Rhizobium sp. (strain NGR234)
Length = 513
Score = 32.7 bits (71), Expect = 8.2
Identities = 14/47 (29%), Positives = 22/47 (46%)
Frame = +1
Query: 295 GVDCVTLGQYMQPTKKHLKVFEYVTPAGSAVGGARPQLGFCTWPAEP 435
G+ Y + +K+H +++ V S V G + GFC W EP
Sbjct: 188 GLSAAPFKGYYEYSKQHAELWRGVVGVASEVFGPAARTGFCYWATEP 234
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 660,752,584
Number of Sequences: 1657284
Number of extensions: 13143718
Number of successful extensions: 45158
Number of sequences better than 10.0: 47
Number of HSP's better than 10.0 without gapping: 43015
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 45118
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 50826451017
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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