Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= br--0079
(650 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q96CW1 Cluster: AP-2 complex subunit mu-1; n=94; Fungi/... 143 4e-33
UniRef50_P35603 Cluster: AP-2 complex subunit mu; n=23; Eukaryot... 133 4e-30
UniRef50_Q3E8F7 Cluster: Uncharacterized protein At5g46630.2; n=... 77 5e-13
UniRef50_Q6CC50 Cluster: Yarrowia lipolytica chromosome C of str... 69 1e-10
UniRef50_Q22V00 Cluster: Adaptor complexes medium subunit family... 66 5e-10
UniRef50_Q00U04 Cluster: Clathrin adaptor complexes medium subun... 64 3e-09
UniRef50_Q1EQ16 Cluster: Mu 2 subunit isoform 2; n=1; Entamoeba ... 61 3e-08
UniRef50_Q09718 Cluster: AP-2 complex subunit mu; n=1; Schizosac... 57 3e-07
UniRef50_Q6CUL9 Cluster: Similar to sp|Q99186 Saccharomyces cere... 55 2e-06
UniRef50_A2FR45 Cluster: Mu adaptin, putative; n=1; Trichomonas ... 52 9e-06
UniRef50_Q7QZ95 Cluster: GLP_567_48751_50055; n=2; Giardia intes... 51 2e-05
UniRef50_Q99186 Cluster: AP-2 complex subunit mu; n=2; Saccharom... 50 4e-05
UniRef50_Q4DZV1 Cluster: Clathrin coat assembly protein, putativ... 49 8e-05
UniRef50_Q4Q1B6 Cluster: Clathrin coat assembly protein-like pro... 48 1e-04
UniRef50_Q5A2L1 Cluster: Potential clathrin-associated protein A... 48 3e-04
UniRef50_Q759G1 Cluster: ADR315Wp; n=1; Eremothecium gossypii|Re... 46 0.001
UniRef50_A2ER69 Cluster: Adaptor complexes medium subunit family... 44 0.002
UniRef50_Q9BXS5 Cluster: AP-1 complex subunit mu-1; n=137; Eukar... 44 0.003
UniRef50_Q22B93 Cluster: Adaptor complexes medium subunit family... 43 0.006
UniRef50_A3LVW0 Cluster: Predicted protein; n=2; Pichia|Rep: Pre... 43 0.007
UniRef50_Q7RKU6 Cluster: Clathrin coat assembly protein ap54; n=... 40 0.068
UniRef50_A7ST88 Cluster: Predicted protein; n=1; Nematostella ve... 38 0.16
UniRef50_A5JZZ1 Cluster: Clathrin coat assembly protein AP50, pu... 38 0.16
UniRef50_A5E396 Cluster: AP-1 complex subunit mu-1; n=6; Sacchar... 38 0.16
UniRef50_Q00776 Cluster: AP-1 complex subunit mu-1 (Mu(1)-adapti... 38 0.16
UniRef50_Q4QBN3 Cluster: Adaptor complex AP-1 medium subunit, pu... 38 0.21
UniRef50_A0BJZ5 Cluster: Chromosome undetermined scaffold_111, w... 37 0.36
UniRef50_Q7RAH7 Cluster: Clathrin coat assembly protein ap50; n=... 36 0.84
UniRef50_Q4N7V8 Cluster: Clathrin medium chain, putative; n=6; A... 36 0.84
UniRef50_A7AS46 Cluster: Clathrin coat adaptor subunit, putative... 36 0.84
UniRef50_Q9SGX7 Cluster: F20B24.16; n=4; Magnoliophyta|Rep: F20B... 34 2.6
UniRef50_Q4UEZ8 Cluster: Clathrin-coat assembly protein, putativ... 34 3.4
UniRef50_A2DPT4 Cluster: Adaptor complexes medium subunit family... 34 3.4
UniRef50_Q6C119 Cluster: Similar to sp|Q00776 Saccharomyces cere... 34 3.4
UniRef50_Q2QR44 Cluster: Retrotransposon protein, putative, uncl... 33 7.8
UniRef50_Q5CWB6 Cluster: Clathrin coat assembly protein AP50; n=... 33 7.8
>UniRef50_Q96CW1 Cluster: AP-2 complex subunit mu-1; n=94;
Fungi/Metazoa group|Rep: AP-2 complex subunit mu-1 -
Homo sapiens (Human)
Length = 435
Score = 143 bits (346), Expect = 4e-33
Identities = 66/77 (85%), Positives = 72/77 (93%)
Frame = +2
Query: 23 VKILTPLNTSGVQLICLKGKAKYKASENAIVWKIKRMAGMKETQLSAEIELLETDTKKKW 202
V+I TPLNTSGVQ+IC+KGKAKYKASENAIVWKIKRMAGMKE+Q+SAEIELL T+ KKKW
Sbjct: 322 VRIPTPLNTSGVQVICMKGKAKYKASENAIVWKIKRMAGMKESQISAEIELLPTNDKKKW 381
Query: 203 TRPPISMGFEVPFAPSG 253
RPPISM FEVPFAPSG
Sbjct: 382 ARPPISMNFEVPFAPSG 398
Score = 83.8 bits (198), Expect = 3e-15
Identities = 35/37 (94%), Positives = 37/37 (100%)
Frame = +1
Query: 253 IKVRYLKVFEPKLNYSDHDVIKWVRYIGRSGLYETRC 363
+KVRYLKVFEPKLNYSDHDVIKWVRYIGRSG+YETRC
Sbjct: 399 LKVRYLKVFEPKLNYSDHDVIKWVRYIGRSGIYETRC 435
>UniRef50_P35603 Cluster: AP-2 complex subunit mu; n=23;
Eukaryota|Rep: AP-2 complex subunit mu - Caenorhabditis
elegans
Length = 441
Score = 133 bits (321), Expect = 4e-30
Identities = 63/79 (79%), Positives = 69/79 (87%), Gaps = 2/79 (2%)
Frame = +2
Query: 23 VKILTPLNTSGVQLICLKGKAKYKASENAIVWKIKRMAGMKETQLSAEIELLETDT--KK 196
V+I TP NTSGVQLIC+KGKAKYKA ENAIVWKIKRMAGMKE+Q+SAEI+LL T KK
Sbjct: 326 VRIPTPPNTSGVQLICMKGKAKYKAGENAIVWKIKRMAGMKESQISAEIDLLSTGNVEKK 385
Query: 197 KWTRPPISMGFEVPFAPSG 253
KW RPP+SM FEVPFAPSG
Sbjct: 386 KWNRPPVSMNFEVPFAPSG 404
Score = 84.6 bits (200), Expect = 2e-15
Identities = 36/37 (97%), Positives = 37/37 (100%)
Frame = +1
Query: 253 IKVRYLKVFEPKLNYSDHDVIKWVRYIGRSGLYETRC 363
+KVRYLKVFEPKLNYSDHDVIKWVRYIGRSGLYETRC
Sbjct: 405 LKVRYLKVFEPKLNYSDHDVIKWVRYIGRSGLYETRC 441
>UniRef50_Q3E8F7 Cluster: Uncharacterized protein At5g46630.2; n=17;
Viridiplantae|Rep: Uncharacterized protein At5g46630.2 -
Arabidopsis thaliana (Mouse-ear cress)
Length = 441
Score = 76.6 bits (180), Expect = 5e-13
Identities = 40/82 (48%), Positives = 50/82 (60%), Gaps = 2/82 (2%)
Frame = +2
Query: 20 LVKILTPLNTSGVQLICLKGKAKYKASENAIVWKIKRMAGMKETQLSAEIELLET-DTKK 196
+VKI P T+ G+AKY S + +VWKI++ G E+ LSAEIEL+ T KK
Sbjct: 326 VVKIPVPKQTAKTNFQVTTGRAKYNPSIDCLVWKIRKFPGQTESTLSAEIELISTMGEKK 385
Query: 197 KWTRPPISMGFEVP-FAPSGSR 259
WTRPPI M F+VP F SG R
Sbjct: 386 SWTRPPIQMEFQVPMFTASGLR 407
>UniRef50_Q6CC50 Cluster: Yarrowia lipolytica chromosome C of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome C of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 419
Score = 68.9 bits (161), Expect = 1e-10
Identities = 32/72 (44%), Positives = 42/72 (58%)
Frame = +2
Query: 20 LVKILTPLNTSGVQLICLKGKAKYKASENAIVWKIKRMAGMKETQLSAEIELLETDTKKK 199
++ I TP N + + GKAKY +S N IVWK+ R++G E L A EL T K
Sbjct: 308 VINIPTPRNAAKTTINASNGKAKYDSSTNQIVWKVSRISGGSEISLRATAELTFTTEKTP 367
Query: 200 WTRPPISMGFEV 235
W +PPISM FE+
Sbjct: 368 WNKPPISMDFEI 379
Score = 39.1 bits (87), Expect = 0.090
Identities = 20/34 (58%), Positives = 24/34 (70%)
Frame = +1
Query: 259 VRYLKVFEPKLNYSDHDVIKWVRYIGRSGLYETR 360
VRYLKVFE K NY+ +KWVRY+ + G YE R
Sbjct: 389 VRYLKVFE-KSNYN---TVKWVRYLMKGGSYEIR 418
>UniRef50_Q22V00 Cluster: Adaptor complexes medium subunit family
protein; n=5; Oligohymenophorea|Rep: Adaptor complexes
medium subunit family protein - Tetrahymena thermophila
SB210
Length = 433
Score = 66.5 bits (155), Expect = 5e-10
Identities = 33/80 (41%), Positives = 44/80 (55%), Gaps = 1/80 (1%)
Frame = +2
Query: 23 VKILTPLNTSGVQLICLKGKAKYKASENAIVWKIKRMAGMKETQLSAEIELLETDTKKKW 202
+K+ P NT+ G+AKY+ + IVW+IK+ G E L EI L T K W
Sbjct: 323 LKVPCPKNTANTSNTASIGRAKYEPEQGGIVWRIKKFQGETEALLRCEIVLSNTALDKNW 382
Query: 203 TRPPISMGFEVP-FAPSGSR 259
+PPIS+ F+VP F SG R
Sbjct: 383 VKPPISLEFQVPSFTASGLR 402
>UniRef50_Q00U04 Cluster: Clathrin adaptor complexes medium subunit
family protein; n=2; Ostreococcus|Rep: Clathrin adaptor
complexes medium subunit family protein - Ostreococcus
tauri
Length = 496
Score = 64.1 bits (149), Expect = 3e-09
Identities = 35/81 (43%), Positives = 46/81 (56%), Gaps = 2/81 (2%)
Frame = +2
Query: 23 VKILTPLNTSGVQLICLKGKAKYKASENAIVWKIKRMAGMKETQLSAEIELLET-DTKKK 199
V+I P T+ + GKAKY E + WKIK++AG +E QL AE+ L T K
Sbjct: 372 VRIPVPKLTARATIRVSAGKAKYVPEEGCLRWKIKKLAGHQELQLDAEVMLANTLSDHKP 431
Query: 200 WTRPPISMGFEVP-FAPSGSR 259
W +PPI++ F VP F SG R
Sbjct: 432 WVQPPINIEFNVPMFTASGLR 452
>UniRef50_Q1EQ16 Cluster: Mu 2 subunit isoform 2; n=1; Entamoeba
histolytica|Rep: Mu 2 subunit isoform 2 - Entamoeba
histolytica
Length = 407
Score = 60.9 bits (141), Expect = 3e-08
Identities = 25/76 (32%), Positives = 42/76 (55%)
Frame = +2
Query: 11 ERSLVKILTPLNTSGVQLICLKGKAKYKASENAIVWKIKRMAGMKETQLSAEIELLETDT 190
E +KI P N + + C G AKY AI+W+I R G + ++ +++L++T
Sbjct: 295 ENVRIKIPVPKNAALCKTRCTAGSAKYHPEHAAILWRISRFNGKTQQTITVDVDLVQTTQ 354
Query: 191 KKKWTRPPISMGFEVP 238
++W +PPI M F +P
Sbjct: 355 SQRWDKPPILMDFVIP 370
>UniRef50_Q09718 Cluster: AP-2 complex subunit mu; n=1;
Schizosaccharomyces pombe|Rep: AP-2 complex subunit mu -
Schizosaccharomyces pombe (Fission yeast)
Length = 446
Score = 57.2 bits (132), Expect = 3e-07
Identities = 31/77 (40%), Positives = 40/77 (51%), Gaps = 1/77 (1%)
Frame = +2
Query: 26 KILTPLNTSGVQLICLKGKAKYKASENAIVWKIKRMAGMKETQLSAEIELLETDTKKKWT 205
+I P N +GKA Y+ SEN I WKI R G E AE+EL T ++ W
Sbjct: 335 RIPVPTNVVKANPRVNRGKAGYEPSENIINWKIPRFLGETELIFYAEVELSNTTNQQIWA 394
Query: 206 RPPISMGFEV-PFAPSG 253
+PPIS+ F + F SG
Sbjct: 395 KPPISLDFNILMFTSSG 411
Score = 32.7 bits (71), Expect = 7.8
Identities = 17/36 (47%), Positives = 23/36 (63%)
Frame = +1
Query: 253 IKVRYLKVFEPKLNYSDHDVIKWVRYIGRSGLYETR 360
+ V+YL+V EP + S + IKWVRY R+G E R
Sbjct: 412 LHVQYLRVSEP--SNSKYKSIKWVRYSTRAGTCEIR 445
>UniRef50_Q6CUL9 Cluster: Similar to sp|Q99186 Saccharomyces
cerevisiae YOL062c APM4 AP-2 complex subunit; n=3;
Saccharomycetales|Rep: Similar to sp|Q99186
Saccharomyces cerevisiae YOL062c APM4 AP-2 complex
subunit - Kluyveromyces lactis (Yeast) (Candida
sphaerica)
Length = 475
Score = 54.8 bits (126), Expect = 2e-06
Identities = 33/82 (40%), Positives = 41/82 (50%), Gaps = 5/82 (6%)
Frame = +2
Query: 23 VKILTPLNTSGVQLICLKGKAKYKASENAIVWKIKRMAGMKETQLSAEIELLET----DT 190
VKI P T GK KY A E +VWK + G E LS ++ + T
Sbjct: 360 VKIPVPPTTIKCDFNVSGGKCKYDAGEKCMVWKYNKYKGSTENTLSGKVAIPATSHDLSD 419
Query: 191 KKKWTRPPISMGFE-VPFAPSG 253
+W+RPPISMGFE V F+ SG
Sbjct: 420 LLRWSRPPISMGFEIVMFSNSG 441
Score = 40.3 bits (90), Expect = 0.039
Identities = 18/34 (52%), Positives = 23/34 (67%)
Frame = +1
Query: 259 VRYLKVFEPKLNYSDHDVIKWVRYIGRSGLYETR 360
VR+LK EP+LNY +KW++YI SG YE R
Sbjct: 444 VRHLKCQEPQLNYQP---VKWIKYISHSGAYEIR 474
>UniRef50_A2FR45 Cluster: Mu adaptin, putative; n=1; Trichomonas
vaginalis G3|Rep: Mu adaptin, putative - Trichomonas
vaginalis G3
Length = 426
Score = 52.4 bits (120), Expect = 9e-06
Identities = 21/73 (28%), Positives = 42/73 (57%)
Frame = +2
Query: 23 VKILTPLNTSGVQLICLKGKAKYKASENAIVWKIKRMAGMKETQLSAEIELLETDTKKKW 202
+++ P + + C G+ +Y ++NA+VW IK+ G K+ L A L +++++
Sbjct: 316 IRVPVPPDVDTPKAQCTAGRMRYSPNDNALVWTIKQFPGRKQFSLRAHFGLPSVESEEEE 375
Query: 203 TRPPISMGFEVPF 241
++ PI + FE+PF
Sbjct: 376 SKRPIVVNFEIPF 388
>UniRef50_Q7QZ95 Cluster: GLP_567_48751_50055; n=2; Giardia
intestinalis|Rep: GLP_567_48751_50055 - Giardia lamblia
ATCC 50803
Length = 434
Score = 51.2 bits (117), Expect = 2e-05
Identities = 26/84 (30%), Positives = 44/84 (52%), Gaps = 3/84 (3%)
Frame = +2
Query: 11 ERSLVKILTPLNTSGVQLICLKGKAKYKASENAIVWKIKRMAGMKETQLSAEIELLETDT 190
E +V + P N S V I GK + + A W+IK + G LS E++ + + +
Sbjct: 318 EHVIVSVPMPSNVSDVTAIESLGKCRLRKDGQAAEWRIKSITGGTTATLSMEVQCVSSSS 377
Query: 191 --KKKWTRPPISMGFEVP-FAPSG 253
++W RPP++M F++P + SG
Sbjct: 378 IDLREWRRPPLAMNFDIPMYTASG 401
>UniRef50_Q99186 Cluster: AP-2 complex subunit mu; n=2;
Saccharomyces cerevisiae|Rep: AP-2 complex subunit mu -
Saccharomyces cerevisiae (Baker's yeast)
Length = 491
Score = 50.4 bits (115), Expect = 4e-05
Identities = 29/83 (34%), Positives = 47/83 (56%), Gaps = 5/83 (6%)
Frame = +2
Query: 20 LVKILTPLNTSGVQLICLKGKAKYKASENAIVWKIKRMAGMKETQLSAEIELLETDTK-- 193
++ I P +T ++ G K+ ENA++W+ + G+ E LSA + + +DT
Sbjct: 376 VLHIPVPPSTVDCKISVSNGHCKFVPEENAMIWRFNKYNGLTENTLSA-VTVSTSDTTQL 434
Query: 194 --KKWTRPPISMGFEV-PFAPSG 253
++WTRPPIS+ FEV F+ SG
Sbjct: 435 NLQQWTRPPISLEFEVMMFSNSG 457
>UniRef50_Q4DZV1 Cluster: Clathrin coat assembly protein, putative;
n=2; Trypanosoma cruzi|Rep: Clathrin coat assembly
protein, putative - Trypanosoma cruzi
Length = 416
Score = 49.2 bits (112), Expect = 8e-05
Identities = 24/76 (31%), Positives = 45/76 (59%), Gaps = 4/76 (5%)
Frame = +2
Query: 23 VKILTPLNTSGVQLICLKGKAKYKASENAIVWKIKRMA-GMKETQLSAEIELLE---TDT 190
++I P NT+ V L +G+ ++ ++A++WK+ ++ +E L+AEI LL +
Sbjct: 301 IRIPCPENTADVNLSVARGRVQFDGVQHAVIWKLPTLSQNDEELLLTAEIVLLAPTIATS 360
Query: 191 KKKWTRPPISMGFEVP 238
++ W+RPPI + F P
Sbjct: 361 EQVWSRPPIKISFTTP 376
Score = 33.1 bits (72), Expect = 5.9
Identities = 17/35 (48%), Positives = 22/35 (62%)
Frame = +1
Query: 256 KVRYLKVFEPKLNYSDHDVIKWVRYIGRSGLYETR 360
+V+ L+V EP L YS KWVRY+ +G YE R
Sbjct: 384 RVKELRVEEPLLRYS---ASKWVRYLTTTGQYEWR 415
>UniRef50_Q4Q1B6 Cluster: Clathrin coat assembly protein-like
protein; n=3; Leishmania|Rep: Clathrin coat assembly
protein-like protein - Leishmania major
Length = 438
Score = 48.4 bits (110), Expect = 1e-04
Identities = 26/72 (36%), Positives = 41/72 (56%), Gaps = 2/72 (2%)
Frame = +2
Query: 23 VKILTPLNTSGVQLICLKGKAKYKASENAIVWKIKRMAGMKETQLSAEI-ELLETD-TKK 196
V + P NT+ ++ GKAKY +AIVWK+ + +E AEI ++ T+ T+
Sbjct: 325 VSVACPDNTATAEVKVGHGKAKYDPVSHAIVWKLPEVKSGEEIAFFAEIRQITPTENTEL 384
Query: 197 KWTRPPISMGFE 232
WT+PPI + F+
Sbjct: 385 LWTKPPIRIAFQ 396
>UniRef50_Q5A2L1 Cluster: Potential clathrin-associated protein AP-2
complex component; n=3; Saccharomycetales|Rep: Potential
clathrin-associated protein AP-2 complex component -
Candida albicans (Yeast)
Length = 470
Score = 47.6 bits (108), Expect = 3e-04
Identities = 25/61 (40%), Positives = 36/61 (59%), Gaps = 2/61 (3%)
Frame = +2
Query: 77 GKAKYKASENAIVWKIKRMAGMKETQLSAEIEL-LETDTKKKWTRPPISMGFEVP-FAPS 250
GK K+ +N+I WK + G +E L+AEIE+ +D WTRPPI + F + F+ S
Sbjct: 377 GKTKFHPEDNSISWKCNKFFGEQEHVLTAEIEVNSSSDELLYWTRPPIKLDFFLDMFSSS 436
Query: 251 G 253
G
Sbjct: 437 G 437
>UniRef50_Q759G1 Cluster: ADR315Wp; n=1; Eremothecium gossypii|Rep:
ADR315Wp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 492
Score = 45.6 bits (103), Expect = 0.001
Identities = 24/57 (42%), Positives = 30/57 (52%), Gaps = 4/57 (7%)
Frame = +2
Query: 77 GKAKYKASENAIVWKIKRMAGMKETQLSAEIELLE----TDTKKKWTRPPISMGFEV 235
GK K+ ENAI+WKI + G+ E LSA E +W RPPISM E+
Sbjct: 358 GKCKFVPEENAIIWKIHKFHGLTENTLSAVTIADEQGHYAQVLDQWPRPPISMKLEI 414
>UniRef50_A2ER69 Cluster: Adaptor complexes medium subunit family
protein; n=1; Trichomonas vaginalis G3|Rep: Adaptor
complexes medium subunit family protein - Trichomonas
vaginalis G3
Length = 433
Score = 44.4 bits (100), Expect = 0.002
Identities = 23/76 (30%), Positives = 39/76 (51%), Gaps = 3/76 (3%)
Frame = +2
Query: 20 LVKILTPLNTSGVQLICLKGKAKYKASENAIVWKIKRMAGMKETQLSAEIELLETDTKKK 199
+VKI P N S Q+ +GK + +NA++WKI AG + ++ + L + T +
Sbjct: 318 IVKIPMPENASETQIEQSQGKGVFVGEQNAVIWKINGFAGKTQADITIYVTCLASTTNES 377
Query: 200 WT---RPPISMGFEVP 238
+ + PIS F +P
Sbjct: 378 PSLKIKDPISCEFNIP 393
>UniRef50_Q9BXS5 Cluster: AP-1 complex subunit mu-1; n=137;
Eukaryota|Rep: AP-1 complex subunit mu-1 - Homo sapiens
(Human)
Length = 423
Score = 44.0 bits (99), Expect = 0.003
Identities = 23/60 (38%), Positives = 31/60 (51%), Gaps = 1/60 (1%)
Frame = +2
Query: 77 GKAKYKASENAIVWKIKRMAGMKETQLSAEIELLETDTKKKWTRPPISMGFEVP-FAPSG 253
G K+ + IVW IK G KE + A L + + K +PPIS+ FE+P F SG
Sbjct: 330 GSVKWVPENSEIVWSIKSFPGGKEYLMRAHFGLPSVEAEDKEGKPPISVKFEIPYFTTSG 389
Score = 33.5 bits (73), Expect = 4.5
Identities = 17/39 (43%), Positives = 24/39 (61%)
Frame = +1
Query: 244 TLRIKVRYLKVFEPKLNYSDHDVIKWVRYIGRSGLYETR 360
T I+VRYLK+ E S + + WVRYI ++G Y+ R
Sbjct: 387 TSGIQVRYLKIIEK----SGYQALPWVRYITQNGDYQLR 421
>UniRef50_Q22B93 Cluster: Adaptor complexes medium subunit family
protein; n=3; Tetrahymena thermophila|Rep: Adaptor
complexes medium subunit family protein - Tetrahymena
thermophila SB210
Length = 444
Score = 43.2 bits (97), Expect = 0.006
Identities = 19/57 (33%), Positives = 34/57 (59%), Gaps = 2/57 (3%)
Frame = +2
Query: 77 GKAKYKASENAIVWKIKRMAGMKETQLSAEIEL--LETDTKKKWTRPPISMGFEVPF 241
G +Y A + A+ WK K+ G +E ++A L + + ++K+ R PIS+ FE+P+
Sbjct: 349 GTVEYVAEKEAMGWKFKQFPGQREYMMTATFHLPTVVSPNREKFQRMPISINFEIPY 405
>UniRef50_A3LVW0 Cluster: Predicted protein; n=2; Pichia|Rep:
Predicted protein - Pichia stipitis (Yeast)
Length = 465
Score = 42.7 bits (96), Expect = 0.007
Identities = 28/92 (30%), Positives = 45/92 (48%), Gaps = 15/92 (16%)
Frame = +2
Query: 23 VKILTPLNTSGVQLICLKGKAKYKASENAIVWKIKRMAGMKETQLSAEIELLET--DTKK 196
+K+ TP GK+K+ +N I+WK + G +E L+AE+EL + DT +
Sbjct: 341 IKVPTPKGVLDSYSSNSAGKSKFHPEDNVILWKFNKFFGEQEHVLTAEVELADNSHDTSQ 400
Query: 197 K------------WTRPPISMGFEVP-FAPSG 253
+ W+RPPI + F + F+ SG
Sbjct: 401 QMAQTNTTNSILNWSRPPIKLDFVIEMFSSSG 432
>UniRef50_Q7RKU6 Cluster: Clathrin coat assembly protein ap54; n=8;
Eukaryota|Rep: Clathrin coat assembly protein ap54 -
Plasmodium yoelii yoelii
Length = 459
Score = 39.5 bits (88), Expect = 0.068
Identities = 16/58 (27%), Positives = 34/58 (58%), Gaps = 3/58 (5%)
Frame = +2
Query: 77 GKAKYKASENAIVWKIKRMAGMKETQLSAEI---ELLETDTKKKWTRPPISMGFEVPF 241
G KY ++ ++WKIK+ G KE ++A+ ++ + K + + P+++ FE+P+
Sbjct: 363 GTVKYYPDKDILLWKIKQFQGQKEYIMNAQFGLPSIVSNENKDIYYKRPVNVKFEIPY 420
Score = 32.7 bits (71), Expect = 7.8
Identities = 16/36 (44%), Positives = 22/36 (61%)
Frame = +1
Query: 253 IKVRYLKVFEPKLNYSDHDVIKWVRYIGRSGLYETR 360
I VRYLK+ E S + + WVRYI ++G Y+ R
Sbjct: 426 ITVRYLKIIEK----SGYQALPWVRYITQNGDYQVR 457
>UniRef50_A7ST88 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 432
Score = 38.3 bits (85), Expect = 0.16
Identities = 14/52 (26%), Positives = 31/52 (59%)
Frame = +2
Query: 83 AKYKASENAIVWKIKRMAGMKETQLSAEIELLETDTKKKWTRPPISMGFEVP 238
A+YK +E ++W++K + G E ++ +++L + + P+S+ FE+P
Sbjct: 350 AEYKTAEKLLLWQVKSIRGGAEVAINIKLKLKDKAKSARKELGPVSLDFEIP 401
>UniRef50_A5JZZ1 Cluster: Clathrin coat assembly protein AP50,
putative; n=2; Plasmodium|Rep: Clathrin coat assembly
protein AP50, putative - Plasmodium vivax
Length = 611
Score = 38.3 bits (85), Expect = 0.16
Identities = 17/32 (53%), Positives = 24/32 (75%)
Frame = +1
Query: 259 VRYLKVFEPKLNYSDHDVIKWVRYIGRSGLYE 354
+RYLKVFE K NY +IKW++Y+ SG+Y+
Sbjct: 582 IRYLKVFE-KSNYK---IIKWIKYLTESGIYQ 609
>UniRef50_A5E396 Cluster: AP-1 complex subunit mu-1; n=6;
Saccharomycetales|Rep: AP-1 complex subunit mu-1 -
Lodderomyces elongisporus (Yeast) (Saccharomyces
elongisporus)
Length = 445
Score = 38.3 bits (85), Expect = 0.16
Identities = 21/62 (33%), Positives = 34/62 (54%), Gaps = 3/62 (4%)
Frame = +2
Query: 77 GKAKYKASENAIVWKIKRMAGMKETQLSAEIEL--LETDTKKKWTRPPISMGFEVP-FAP 247
G K+ ++ +VWK+K G K +SAE+ L + DT+ ++ PI + F +P F
Sbjct: 348 GSVKWIPEKSCLVWKLKTFPGGKLFTMSAELGLPAVMDDTENILSKKPIKVNFSIPYFTT 407
Query: 248 SG 253
SG
Sbjct: 408 SG 409
Score = 37.5 bits (83), Expect = 0.28
Identities = 18/34 (52%), Positives = 23/34 (67%)
Frame = +1
Query: 244 TLRIKVRYLKVFEPKLNYSDHDVIKWVRYIGRSG 345
T I+VRYL++ EPKL Y + WVRYI +SG
Sbjct: 407 TSGIQVRYLRINEPKLQYQSY---PWVRYITKSG 437
>UniRef50_Q00776 Cluster: AP-1 complex subunit mu-1 (Mu(1)-adaptin);
n=5; Saccharomycetales|Rep: AP-1 complex subunit mu-1
(Mu(1)-adaptin) - Saccharomyces cerevisiae (Baker's
yeast)
Length = 475
Score = 38.3 bits (85), Expect = 0.16
Identities = 19/34 (55%), Positives = 23/34 (67%)
Frame = +1
Query: 244 TLRIKVRYLKVFEPKLNYSDHDVIKWVRYIGRSG 345
T I+VRYLK+ EPKL Y + WVRYI +SG
Sbjct: 437 TSGIQVRYLKINEPKLQYKSY---PWVRYITQSG 467
Score = 34.7 bits (76), Expect = 1.9
Identities = 19/62 (30%), Positives = 28/62 (45%)
Frame = +2
Query: 77 GKAKYKASENAIVWKIKRMAGMKETQLSAEIELLETDTKKKWTRPPISMGFEVPFAPSGS 256
G KY ++AI+WKI+ G KE +SAE+ L + R E+ P
Sbjct: 369 GSLKYVPEKSAILWKIRSFPGGKEYSMSAELGLPSISNNEDGNRTMPKSNAEILKGPVQI 428
Query: 257 RF 262
+F
Sbjct: 429 KF 430
>UniRef50_Q4QBN3 Cluster: Adaptor complex AP-1 medium subunit,
putative; n=8; Trypanosomatidae|Rep: Adaptor complex
AP-1 medium subunit, putative - Leishmania major
Length = 433
Score = 37.9 bits (84), Expect = 0.21
Identities = 19/62 (30%), Positives = 33/62 (53%), Gaps = 3/62 (4%)
Frame = +2
Query: 77 GKAKYKASENAIVWKIKRMAGMKETQLSAEIEL--LETDTKKKWTRPPISMGFEVP-FAP 247
G +Y NA++W + ++AG + SAE L + + K ++ P+ + F +P FA
Sbjct: 338 GHLQYAPQMNALIWNLGKIAGNRHCSCSAEFHLPSIRSSDMKDLSKMPVKVRFVIPYFAA 397
Query: 248 SG 253
SG
Sbjct: 398 SG 399
Score = 33.1 bits (72), Expect = 5.9
Identities = 18/35 (51%), Positives = 23/35 (65%)
Frame = +1
Query: 256 KVRYLKVFEPKLNYSDHDVIKWVRYIGRSGLYETR 360
+VRY+KV E K NY WVRY+ +SG+YE R
Sbjct: 401 QVRYVKVSE-KSNYV---ATPWVRYVTQSGVYEIR 431
>UniRef50_A0BJZ5 Cluster: Chromosome undetermined scaffold_111,
whole genome shotgun sequence; n=3;
Oligohymenophorea|Rep: Chromosome undetermined
scaffold_111, whole genome shotgun sequence - Paramecium
tetraurelia
Length = 439
Score = 37.1 bits (82), Expect = 0.36
Identities = 17/54 (31%), Positives = 31/54 (57%), Gaps = 2/54 (3%)
Frame = +2
Query: 83 AKYKASENAIVWKIKRMAGMKETQLSAEIELLETDTKKKWTRP--PISMGFEVP 238
A+Y +++ + W+IK++ G +E L ++ L T T + PI+M FE+P
Sbjct: 346 AEYDSNKKMVEWQIKKLCGGQERSLKIKLTLQATQTAHTARKEIGPIAMNFEIP 399
>UniRef50_Q7RAH7 Cluster: Clathrin coat assembly protein ap50; n=5;
Plasmodium (Vinckeia)|Rep: Clathrin coat assembly
protein ap50 - Plasmodium yoelii yoelii
Length = 601
Score = 35.9 bits (79), Expect = 0.84
Identities = 16/32 (50%), Positives = 23/32 (71%)
Frame = +1
Query: 259 VRYLKVFEPKLNYSDHDVIKWVRYIGRSGLYE 354
+RYLKV+E K NY +IKW++Y+ SG Y+
Sbjct: 572 IRYLKVYE-KSNYK---IIKWIKYLTESGAYQ 599
>UniRef50_Q4N7V8 Cluster: Clathrin medium chain, putative; n=6;
Alveolata|Rep: Clathrin medium chain, putative -
Theileria parva
Length = 452
Score = 35.9 bits (79), Expect = 0.84
Identities = 15/58 (25%), Positives = 32/58 (55%), Gaps = 2/58 (3%)
Frame = +2
Query: 74 KGKAKYKASENAIVWKIKRMAGMKETQLSAEIEL--LETDTKKKWTRPPISMGFEVPF 241
+G KY ++AI W +K+ G K + A L + +++ +++ P+ + FE+P+
Sbjct: 356 QGSVKYLPDQDAITWYVKQFQGDKVYTMFASFGLPSVSDESRNTFSKNPVKIKFEIPY 413
>UniRef50_A7AS46 Cluster: Clathrin coat adaptor subunit, putative;
n=1; Babesia bovis|Rep: Clathrin coat adaptor subunit,
putative - Babesia bovis
Length = 474
Score = 35.9 bits (79), Expect = 0.84
Identities = 16/67 (23%), Positives = 34/67 (50%)
Frame = +2
Query: 38 PLNTSGVQLICLKGKAKYKASENAIVWKIKRMAGMKETQLSAEIELLETDTKKKWTRPPI 217
P+N S V++I G+ + K +EN + W + ++ G + L ++ T P+
Sbjct: 366 PINASHVEIISNAGQCQIKIAENMVHWHLGKVYGQTILSMEFHCRLTKSITGVSTHLSPL 425
Query: 218 SMGFEVP 238
++ F++P
Sbjct: 426 ALHFDLP 432
>UniRef50_Q9SGX7 Cluster: F20B24.16; n=4; Magnoliophyta|Rep:
F20B24.16 - Arabidopsis thaliana (Mouse-ear cress)
Length = 411
Score = 34.3 bits (75), Expect = 2.6
Identities = 19/36 (52%), Positives = 22/36 (61%)
Frame = +1
Query: 253 IKVRYLKVFEPKLNYSDHDVIKWVRYIGRSGLYETR 360
I+VRYLK+ E K Y H WVRYI +G YE R
Sbjct: 378 IQVRYLKIIE-KSGYQAHP---WVRYITMAGEYELR 409
>UniRef50_Q4UEZ8 Cluster: Clathrin-coat assembly protein, putative;
n=2; Theileria|Rep: Clathrin-coat assembly protein,
putative - Theileria annulata
Length = 461
Score = 33.9 bits (74), Expect = 3.4
Identities = 18/52 (34%), Positives = 27/52 (51%)
Frame = +2
Query: 83 AKYKASENAIVWKIKRMAGMKETQLSAEIELLETDTKKKWTRPPISMGFEVP 238
++YK N I W IK + G E L++EI ++ PI++ FEVP
Sbjct: 387 SEYKLENNTISWNIKNIQGSSEVVLNSEIVFNNKVNSNQF--GPINLIFEVP 436
>UniRef50_A2DPT4 Cluster: Adaptor complexes medium subunit family
protein; n=1; Trichomonas vaginalis G3|Rep: Adaptor
complexes medium subunit family protein - Trichomonas
vaginalis G3
Length = 428
Score = 33.9 bits (74), Expect = 3.4
Identities = 22/71 (30%), Positives = 30/71 (42%), Gaps = 4/71 (5%)
Frame = +2
Query: 38 PLNTSGVQLICL-KGKAKYKASENAIVWKIKRMAGMKETQLSAEIELLETDTKKK---WT 205
P NT+ V C K +AK+ +NA VW I G +Q+ + L K
Sbjct: 315 PQNTANVTFECAEKTRAKFDELKNAAVWTINDFVGQGHSQIVIIAQYLSASYKSSPATKL 374
Query: 206 RPPISMGFEVP 238
PIS F +P
Sbjct: 375 NKPISAEFHIP 385
>UniRef50_Q6C119 Cluster: Similar to sp|Q00776 Saccharomyces
cerevisiae YPL259c APM1 AP-1 complex subunit; n=1;
Yarrowia lipolytica|Rep: Similar to sp|Q00776
Saccharomyces cerevisiae YPL259c APM1 AP-1 complex
subunit - Yarrowia lipolytica (Candida lipolytica)
Length = 514
Score = 33.9 bits (74), Expect = 3.4
Identities = 16/31 (51%), Positives = 21/31 (67%)
Frame = +1
Query: 253 IKVRYLKVFEPKLNYSDHDVIKWVRYIGRSG 345
++VRYLKV EP L Y + WVRYI ++G
Sbjct: 453 LQVRYLKVNEPTLKYRS---LPWVRYITKNG 480
>UniRef50_Q2QR44 Cluster: Retrotransposon protein, putative,
unclassified; n=20; Oryza sativa|Rep: Retrotransposon
protein, putative, unclassified - Oryza sativa subsp.
japonica (Rice)
Length = 1006
Score = 32.7 bits (71), Expect = 7.8
Identities = 18/50 (36%), Positives = 25/50 (50%), Gaps = 1/50 (2%)
Frame = -2
Query: 349 RVRSVRCSAPT**RHGP-SNSASVRTPSGSEP*SGGCKGNFEPHGDGRAR 203
R ++ S P HGP + S RTP+G+ P +G G+ P GD R
Sbjct: 408 RSKAAGPSQPLGRAHGPHTGSGPERTPAGTRPAAGDSGGDVPPGGDSETR 457
>UniRef50_Q5CWB6 Cluster: Clathrin coat assembly protein AP50; n=2;
Cryptosporidium|Rep: Clathrin coat assembly protein AP50
- Cryptosporidium parvum Iowa II
Length = 548
Score = 32.7 bits (71), Expect = 7.8
Identities = 20/61 (32%), Positives = 33/61 (54%), Gaps = 2/61 (3%)
Frame = +2
Query: 62 LICLKGKAKYKASENAIVWKIKRMAGMKETQLSAEIEL-LETDTKK-KWTRPPISMGFEV 235
LI ++ ++Y I+WKIK++ G E L ++I L ETD + P+ + FE+
Sbjct: 447 LIPVQQTSQYDDKNQRIIWKIKKIHGGTEIILKSKICLSFETDLNSIRKKIGPLFLNFEI 506
Query: 236 P 238
P
Sbjct: 507 P 507
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 507,666,652
Number of Sequences: 1657284
Number of extensions: 8789028
Number of successful extensions: 25409
Number of sequences better than 10.0: 36
Number of HSP's better than 10.0 without gapping: 24632
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 25390
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 48760335122
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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