Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= br--0006
(609 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X06745-1|CAA29920.1| 1462|Homo sapiens protein ( Human mRNA for ... 103 5e-22
AY275833-1|AAP13534.1| 1462|Homo sapiens polymerase (DNA directe... 103 5e-22
M81735-1|AAA35768.1| 1107|Homo sapiens DNA polymerase delta prot... 43 7e-04
M80397-1|AAA58439.1| 1107|Homo sapiens DNA polymerase-delta cata... 43 7e-04
DQ234348-1|ABB29977.1| 1133|Homo sapiens DNA-directed polymerase... 43 7e-04
BC008800-1|AAH08800.1| 1107|Homo sapiens polymerase (DNA directe... 43 7e-04
AY129569-1|AAM76971.1| 1107|Homo sapiens polymerase (DNA directe... 43 7e-04
AB209560-1|BAD92797.1| 1011|Homo sapiens polymerase (DNA directe... 43 7e-04
BC146792-1|AAI46793.1| 2624|Homo sapiens B double prime 1, subun... 33 1.0
AJ279120-1|CAC21448.1| 2187|Homo sapiens TFNR protein. 33 1.0
AJ238520-1|CAC04245.1| 2254|Homo sapiens putative transcription ... 33 1.0
AB051476-1|BAB21780.3| 2627|Homo sapiens KIAA1689 protein protein. 33 1.0
BC012072-1|AAH12072.1| 652|Homo sapiens CHFR protein protein. 31 3.2
AK027687-1|BAB55297.1| 652|Homo sapiens protein ( Homo sapiens ... 31 3.2
AF170724-1|AAF91084.1| 664|Homo sapiens cell cycle checkpoint p... 31 3.2
X67318-1|CAA47732.1| 419|Homo sapiens carboxypeptidase a protein. 30 7.3
BT007313-1|AAP35977.1| 419|Homo sapiens carboxypeptidase A1 (pa... 30 7.3
BC005279-1|AAH05279.1| 419|Homo sapiens carboxypeptidase A1 (pa... 30 7.3
AK001658-1|BAA91817.1| 623|Homo sapiens protein ( Homo sapiens ... 29 9.7
>X06745-1|CAA29920.1| 1462|Homo sapiens protein ( Human mRNA for DNA
polymerase alpha-subunit. ).
Length = 1462
Score = 103 bits (247), Expect = 5e-22
Identities = 45/87 (51%), Positives = 65/87 (74%)
Frame = +3
Query: 255 VALRLNSKNSRRFKKGDIVPYIICEDGTANSATQRAYHIEELKNSEHLKVDFKYYLAHQL 434
VAL +NS+ R+ K GD V Y+IC+DG+ +A+QRAY E+L+ ++L +D +YYLA Q+
Sbjct: 1157 VALWINSQGGRKVKAGDTVSYVICQDGSNLTASQRAYAPEQLQKQDNLTIDTQYYLAQQI 1216
Query: 435 HPVISRICEPIEGMDPARVADCLGLIP 515
HPV++RICEPI+G+D +A LGL P
Sbjct: 1217 HPVVARICEPIDGIDAVLIATWLGLDP 1243
Score = 81.0 bits (191), Expect = 3e-15
Identities = 39/96 (40%), Positives = 60/96 (62%)
Frame = +1
Query: 10 RGLDIVRLDWSXLAAEAGKFILSQILSEQTPDDRLESIQNHLNKLKDDLIGNKMPLSVLA 189
+GLDIVR DW LA + G F++ QILS+Q+ D +E+IQ L ++ ++++ +P+S
Sbjct: 1075 KGLDIVRRDWCDLAKDTGNFVIGQILSDQSRDTIVENIQKRLIEIGENVLNGSVPVSQFE 1134
Query: 190 ITKQLTKNPNEYADKHTQSHVQWH*GLTVKTVGDSK 297
I K LTK+P +Y DK + HV H L + + G K
Sbjct: 1135 INKALTKDPQDYPDKKSLPHV--HVALWINSQGGRK 1168
>AY275833-1|AAP13534.1| 1462|Homo sapiens polymerase (DNA directed),
alpha protein.
Length = 1462
Score = 103 bits (247), Expect = 5e-22
Identities = 45/87 (51%), Positives = 65/87 (74%)
Frame = +3
Query: 255 VALRLNSKNSRRFKKGDIVPYIICEDGTANSATQRAYHIEELKNSEHLKVDFKYYLAHQL 434
VAL +NS+ R+ K GD V Y+IC+DG+ +A+QRAY E+L+ ++L +D +YYLA Q+
Sbjct: 1157 VALWINSQGGRKVKAGDTVSYVICQDGSNLTASQRAYAPEQLQKQDNLTIDTQYYLAQQI 1216
Query: 435 HPVISRICEPIEGMDPARVADCLGLIP 515
HPV++RICEPI+G+D +A LGL P
Sbjct: 1217 HPVVARICEPIDGIDAVLIATWLGLDP 1243
Score = 81.0 bits (191), Expect = 3e-15
Identities = 39/96 (40%), Positives = 60/96 (62%)
Frame = +1
Query: 10 RGLDIVRLDWSXLAAEAGKFILSQILSEQTPDDRLESIQNHLNKLKDDLIGNKMPLSVLA 189
+GLDIVR DW LA + G F++ QILS+Q+ D +E+IQ L ++ ++++ +P+S
Sbjct: 1075 KGLDIVRRDWCDLAKDTGNFVIGQILSDQSRDTIVENIQKRLIEIGENVLNGSVPVSQFE 1134
Query: 190 ITKQLTKNPNEYADKHTQSHVQWH*GLTVKTVGDSK 297
I K LTK+P +Y DK + HV H L + + G K
Sbjct: 1135 INKALTKDPQDYPDKKSLPHV--HVALWINSQGGRK 1168
>M81735-1|AAA35768.1| 1107|Homo sapiens DNA polymerase delta protein.
Length = 1107
Score = 43.2 bits (97), Expect = 7e-04
Identities = 27/82 (32%), Positives = 48/82 (58%)
Frame = +1
Query: 10 RGLDIVRLDWSXLAAEAGKFILSQILSEQTPDDRLESIQNHLNKLKDDLIGNKMPLSVLA 189
+GL+ VR D L A L ++L ++ P+ + Q+ ++ DL+ N++ +S L
Sbjct: 827 KGLEAVRRDNCPLVANLVTASLRRLLIDRDPEGAVAHAQDVIS----DLLCNRIDISQLV 882
Query: 190 ITKQLTKNPNEYADKHTQSHVQ 255
ITK+LT+ ++YA K Q+HV+
Sbjct: 883 ITKELTRAASDYAGK--QAHVE 902
Score = 34.3 bits (75), Expect = 0.34
Identities = 23/59 (38%), Positives = 31/59 (52%), Gaps = 1/59 (1%)
Frame = +3
Query: 300 GDIVPYIICEDGTANSATQRAYHIEELKNSEH-LKVDFKYYLAHQLHPVISRICEPIEG 473
GD VPY+I +A ++ + L EH L +D +YYL QL + RI EPI G
Sbjct: 919 GDRVPYVIISAAKGVAAYMKSE--DPLFVLEHSLPIDTQYYLEQQLAKPLLRIFEPILG 975
>M80397-1|AAA58439.1| 1107|Homo sapiens DNA polymerase-delta
catalytic-subunit protein.
Length = 1107
Score = 43.2 bits (97), Expect = 7e-04
Identities = 27/82 (32%), Positives = 48/82 (58%)
Frame = +1
Query: 10 RGLDIVRLDWSXLAAEAGKFILSQILSEQTPDDRLESIQNHLNKLKDDLIGNKMPLSVLA 189
+GL+ VR D L A L ++L ++ P+ + Q+ ++ DL+ N++ +S L
Sbjct: 827 KGLEAVRRDNCPLVANLVTASLRRLLIDRDPEGAVAHAQDVIS----DLLCNRIDISQLV 882
Query: 190 ITKQLTKNPNEYADKHTQSHVQ 255
ITK+LT+ ++YA K Q+HV+
Sbjct: 883 ITKELTRAASDYAGK--QAHVE 902
Score = 34.3 bits (75), Expect = 0.34
Identities = 23/59 (38%), Positives = 31/59 (52%), Gaps = 1/59 (1%)
Frame = +3
Query: 300 GDIVPYIICEDGTANSATQRAYHIEELKNSEH-LKVDFKYYLAHQLHPVISRICEPIEG 473
GD VPY+I +A ++ + L EH L +D +YYL QL + RI EPI G
Sbjct: 919 GDRVPYVIISAAKGVAAYMKSE--DPLFVLEHSLPIDTQYYLEQQLAKPLLRIFEPILG 975
>DQ234348-1|ABB29977.1| 1133|Homo sapiens DNA-directed polymerase
delta 1 protein.
Length = 1133
Score = 43.2 bits (97), Expect = 7e-04
Identities = 27/82 (32%), Positives = 48/82 (58%)
Frame = +1
Query: 10 RGLDIVRLDWSXLAAEAGKFILSQILSEQTPDDRLESIQNHLNKLKDDLIGNKMPLSVLA 189
+GL+ VR D L A L ++L ++ P+ + Q+ ++ DL+ N++ +S L
Sbjct: 853 KGLEAVRRDNCPLVANLVTASLRRLLIDRDPEGAVAHAQDVIS----DLLCNRIDISQLV 908
Query: 190 ITKQLTKNPNEYADKHTQSHVQ 255
ITK+LT+ ++YA K Q+HV+
Sbjct: 909 ITKELTRAASDYAGK--QAHVE 928
Score = 34.3 bits (75), Expect = 0.34
Identities = 23/59 (38%), Positives = 31/59 (52%), Gaps = 1/59 (1%)
Frame = +3
Query: 300 GDIVPYIICEDGTANSATQRAYHIEELKNSEH-LKVDFKYYLAHQLHPVISRICEPIEG 473
GD VPY+I +A ++ + L EH L +D +YYL QL + RI EPI G
Sbjct: 945 GDRVPYVIISAAKGVAAYMKSE--DPLFVLEHSLPIDTQYYLEQQLAKPLLRIFEPILG 1001
>BC008800-1|AAH08800.1| 1107|Homo sapiens polymerase (DNA directed),
delta 1, catalytic subunit 125kDa protein.
Length = 1107
Score = 43.2 bits (97), Expect = 7e-04
Identities = 27/82 (32%), Positives = 48/82 (58%)
Frame = +1
Query: 10 RGLDIVRLDWSXLAAEAGKFILSQILSEQTPDDRLESIQNHLNKLKDDLIGNKMPLSVLA 189
+GL+ VR D L A L ++L ++ P+ + Q+ ++ DL+ N++ +S L
Sbjct: 827 KGLEAVRRDNCPLVANLVTASLRRLLIDRDPEGAVAHAQDVIS----DLLCNRIDISQLV 882
Query: 190 ITKQLTKNPNEYADKHTQSHVQ 255
ITK+LT+ ++YA K Q+HV+
Sbjct: 883 ITKELTRAASDYAGK--QAHVE 902
Score = 34.3 bits (75), Expect = 0.34
Identities = 23/59 (38%), Positives = 31/59 (52%), Gaps = 1/59 (1%)
Frame = +3
Query: 300 GDIVPYIICEDGTANSATQRAYHIEELKNSEH-LKVDFKYYLAHQLHPVISRICEPIEG 473
GD VPY+I +A ++ + L EH L +D +YYL QL + RI EPI G
Sbjct: 919 GDRVPYVIISAAKGVAAYMKSE--DPLFVLEHSLPIDTQYYLEQQLAKPLLRIFEPILG 975
>AY129569-1|AAM76971.1| 1107|Homo sapiens polymerase (DNA directed),
delta 1, catalytic subunit protein.
Length = 1107
Score = 43.2 bits (97), Expect = 7e-04
Identities = 27/82 (32%), Positives = 48/82 (58%)
Frame = +1
Query: 10 RGLDIVRLDWSXLAAEAGKFILSQILSEQTPDDRLESIQNHLNKLKDDLIGNKMPLSVLA 189
+GL+ VR D L A L ++L ++ P+ + Q+ ++ DL+ N++ +S L
Sbjct: 827 KGLEAVRRDNCPLVANLVTASLRRLLIDRDPEGAVAHAQDVIS----DLLCNRIDISQLV 882
Query: 190 ITKQLTKNPNEYADKHTQSHVQ 255
ITK+LT+ ++YA K Q+HV+
Sbjct: 883 ITKELTRAASDYAGK--QAHVE 902
Score = 34.3 bits (75), Expect = 0.34
Identities = 23/59 (38%), Positives = 31/59 (52%), Gaps = 1/59 (1%)
Frame = +3
Query: 300 GDIVPYIICEDGTANSATQRAYHIEELKNSEH-LKVDFKYYLAHQLHPVISRICEPIEG 473
GD VPY+I +A ++ + L EH L +D +YYL QL + RI EPI G
Sbjct: 919 GDRVPYVIISAAKGVAAYMKSE--DPLFVLEHSLPIDTQYYLEQQLAKPLLRIFEPILG 975
>AB209560-1|BAD92797.1| 1011|Homo sapiens polymerase (DNA directed),
delta 1, catalytic subunit 125kDa variant protein.
Length = 1011
Score = 43.2 bits (97), Expect = 7e-04
Identities = 27/82 (32%), Positives = 48/82 (58%)
Frame = +1
Query: 10 RGLDIVRLDWSXLAAEAGKFILSQILSEQTPDDRLESIQNHLNKLKDDLIGNKMPLSVLA 189
+GL+ VR D L A L ++L ++ P+ + Q+ ++ DL+ N++ +S L
Sbjct: 829 KGLEAVRRDNCPLVANLVTASLRRLLIDRDPEGAVAHAQDVIS----DLLCNRIDISQLV 884
Query: 190 ITKQLTKNPNEYADKHTQSHVQ 255
ITK+LT+ ++YA K Q+HV+
Sbjct: 885 ITKELTRAASDYAGK--QAHVE 904
>BC146792-1|AAI46793.1| 2624|Homo sapiens B double prime 1, subunit of
RNA polymerase III transcription initiation factor
protein.
Length = 2624
Score = 32.7 bits (71), Expect = 1.0
Identities = 15/33 (45%), Positives = 20/33 (60%)
Frame = +2
Query: 488 RCRLPRPDPSGYKQAVKRETNDSETYEVENEQE 586
R R RP P+ + A+KRET +SE Y E + E
Sbjct: 1435 RSRFKRPKPNLARAALKRETTESEKYIYEKKSE 1467
>AJ279120-1|CAC21448.1| 2187|Homo sapiens TFNR protein.
Length = 2187
Score = 32.7 bits (71), Expect = 1.0
Identities = 15/33 (45%), Positives = 20/33 (60%)
Frame = +2
Query: 488 RCRLPRPDPSGYKQAVKRETNDSETYEVENEQE 586
R R RP P+ + A+KRET +SE Y E + E
Sbjct: 1435 RSRFKRPKPNLARAALKRETTESEKYIYEKKSE 1467
>AJ238520-1|CAC04245.1| 2254|Homo sapiens putative transcription
factor-like nuclear regulator protein.
Length = 2254
Score = 32.7 bits (71), Expect = 1.0
Identities = 15/33 (45%), Positives = 20/33 (60%)
Frame = +2
Query: 488 RCRLPRPDPSGYKQAVKRETNDSETYEVENEQE 586
R R RP P+ + A+KRET +SE Y E + E
Sbjct: 1435 RSRFKRPKPNLARAALKRETTESEKYIYEKKSE 1467
>AB051476-1|BAB21780.3| 2627|Homo sapiens KIAA1689 protein protein.
Length = 2627
Score = 32.7 bits (71), Expect = 1.0
Identities = 15/33 (45%), Positives = 20/33 (60%)
Frame = +2
Query: 488 RCRLPRPDPSGYKQAVKRETNDSETYEVENEQE 586
R R RP P+ + A+KRET +SE Y E + E
Sbjct: 1438 RSRFKRPKPNLARAALKRETTESEKYIYEKKSE 1470
>BC012072-1|AAH12072.1| 652|Homo sapiens CHFR protein protein.
Length = 652
Score = 31.1 bits (67), Expect = 3.2
Identities = 11/29 (37%), Positives = 15/29 (51%)
Frame = -2
Query: 326 TYNVRHNVAFFESPTVFTVKPQCHWT*DC 240
TY R N+ E P T +P C+W +C
Sbjct: 601 TYQYRQNIPASELPVAVTSRPDCYWGRNC 629
>AK027687-1|BAB55297.1| 652|Homo sapiens protein ( Homo sapiens
cDNA FLJ14781 fis, clone NT2RP4000455, weakly similar to
TRANS-ACTING TRANSCRIPTIONAL PROTEIN ICP0. ).
Length = 652
Score = 31.1 bits (67), Expect = 3.2
Identities = 11/29 (37%), Positives = 15/29 (51%)
Frame = -2
Query: 326 TYNVRHNVAFFESPTVFTVKPQCHWT*DC 240
TY R N+ E P T +P C+W +C
Sbjct: 601 TYQYRQNIPASELPVAVTSRPDCYWGRNC 629
>AF170724-1|AAF91084.1| 664|Homo sapiens cell cycle checkpoint
protein CHFR protein.
Length = 664
Score = 31.1 bits (67), Expect = 3.2
Identities = 11/29 (37%), Positives = 15/29 (51%)
Frame = -2
Query: 326 TYNVRHNVAFFESPTVFTVKPQCHWT*DC 240
TY R N+ E P T +P C+W +C
Sbjct: 613 TYQYRQNIPASELPVAVTSRPDCYWGRNC 641
>X67318-1|CAA47732.1| 419|Homo sapiens carboxypeptidase a protein.
Length = 419
Score = 29.9 bits (64), Expect = 7.3
Identities = 28/108 (25%), Positives = 47/108 (43%), Gaps = 5/108 (4%)
Frame = +3
Query: 291 FKKGDIVPYIICEDGTANSATQRAYHIEELKNSEHLKVDFKYYLAHQLHPVISRICEPIE 470
F K D V + + A+ A + ++EL++ EHL++DF AH P+ R+ P
Sbjct: 15 FGKEDFVGHQVLRISVADEA--QVQKVKELEDLEHLQLDFWRGPAHPGSPIDVRV--PFP 70
Query: 471 GMDPARV-ADCLGL----IPPDTNKLLKEKPTTRKLMRSRTNKKSTDN 599
+ ++ + G+ + D LL E+ RSR T N
Sbjct: 71 SIQAVKIFLESHGISYETMIEDVQSLLDEEQEQMFAFRSRARSTDTFN 118
>BT007313-1|AAP35977.1| 419|Homo sapiens carboxypeptidase A1
(pancreatic) protein.
Length = 419
Score = 29.9 bits (64), Expect = 7.3
Identities = 28/108 (25%), Positives = 47/108 (43%), Gaps = 5/108 (4%)
Frame = +3
Query: 291 FKKGDIVPYIICEDGTANSATQRAYHIEELKNSEHLKVDFKYYLAHQLHPVISRICEPIE 470
F K D V + + A+ A + ++EL++ EHL++DF AH P+ R+ P
Sbjct: 15 FGKEDFVGHQVLRISVADEA--QVQKVKELEDLEHLQLDFWRGPAHPGSPIDVRV--PFP 70
Query: 471 GMDPARV-ADCLGL----IPPDTNKLLKEKPTTRKLMRSRTNKKSTDN 599
+ ++ + G+ + D LL E+ RSR T N
Sbjct: 71 SIQAVKIFLESHGISYETMIEDVQSLLDEEQEQMFAFRSRARSTDTFN 118
>BC005279-1|AAH05279.1| 419|Homo sapiens carboxypeptidase A1
(pancreatic) protein.
Length = 419
Score = 29.9 bits (64), Expect = 7.3
Identities = 28/108 (25%), Positives = 47/108 (43%), Gaps = 5/108 (4%)
Frame = +3
Query: 291 FKKGDIVPYIICEDGTANSATQRAYHIEELKNSEHLKVDFKYYLAHQLHPVISRICEPIE 470
F K D V + + A+ A + ++EL++ EHL++DF AH P+ R+ P
Sbjct: 15 FGKEDFVGHQVLRISVADEA--QVQKVKELEDLEHLQLDFWRGPAHPGSPIDVRV--PFP 70
Query: 471 GMDPARV-ADCLGL----IPPDTNKLLKEKPTTRKLMRSRTNKKSTDN 599
+ ++ + G+ + D LL E+ RSR T N
Sbjct: 71 SIQAVKIFLESHGISYETMIEDVQSLLDEEQEQMFAFRSRARSTDTFN 118
>AK001658-1|BAA91817.1| 623|Homo sapiens protein ( Homo sapiens
cDNA FLJ10796 fis, clone NT2RP4000648, weakly similar to
TRANS-ACTING TRANSCRIPTIONAL PROTEIN ICP0. ).
Length = 623
Score = 29.5 bits (63), Expect = 9.7
Identities = 10/29 (34%), Positives = 15/29 (51%)
Frame = -2
Query: 326 TYNVRHNVAFFESPTVFTVKPQCHWT*DC 240
TY + N+ E P T +P C+W +C
Sbjct: 572 TYQYQQNIPASELPVAVTSRPDCYWGRNC 600
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 85,287,360
Number of Sequences: 237096
Number of extensions: 1741236
Number of successful extensions: 3974
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 3855
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3974
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 6466646650
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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