Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmte9a13
(413 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI0000D56743 Cluster: PREDICTED: similar to 3-hydroxyi... 144 8e-34
UniRef50_A7UBP6 Cluster: Putative 3-hydroxyisobutyrate dehydroge... 133 2e-30
UniRef50_Q7NWA9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=7... 132 4e-30
UniRef50_P31937 Cluster: 3-hydroxyisobutyrate dehydrogenase, mit... 130 8e-30
UniRef50_Q54CX6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3... 129 2e-29
UniRef50_P28811 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=7... 129 2e-29
UniRef50_Q399N0 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=7... 119 2e-26
UniRef50_Q1AVA4 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 117 1e-25
UniRef50_A7JGH8 Cluster: Predicted protein; n=1; Francisella tul... 116 2e-25
UniRef50_A6NVP0 Cluster: Putative uncharacterized protein; n=1; ... 116 3e-25
UniRef50_Q9K9L1 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 113 2e-24
UniRef50_A3I4V2 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 112 3e-24
UniRef50_Q12CU4 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 110 1e-23
UniRef50_Q55702 Cluster: Uncharacterized oxidoreductase slr0229;... 110 1e-23
UniRef50_Q0K0E2 Cluster: 3-Hydroxyisobutyrate dehydrogenase; n=1... 109 2e-23
UniRef50_Q9V8M5 Cluster: Probable 3-hydroxyisobutyrate dehydroge... 109 3e-23
UniRef50_O34948 Cluster: Uncharacterized oxidoreductase ykwC; n=... 108 5e-23
UniRef50_Q8ES28 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 107 7e-23
UniRef50_Q4FMJ3 Cluster: 6-phosphogluconate dehydrogenase; n=2; ... 107 7e-23
UniRef50_A0UF54 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 107 7e-23
UniRef50_Q83D20 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=9... 106 2e-22
UniRef50_A1QPH6 Cluster: 3-hydroxyisobutyrate dehydrogenase mmsB... 105 3e-22
UniRef50_Q0QLF5 Cluster: 2-hydroxymethyl glutarate dehydrogenase... 105 3e-22
UniRef50_P63936 Cluster: Probable 3-hydroxyisobutyrate dehydroge... 105 3e-22
UniRef50_A0QSJ0 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3... 104 6e-22
UniRef50_A4IN46 Cluster: 3-hydroxyisobutyrate dehydrogenase-like... 102 3e-21
UniRef50_A2U9T6 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 102 3e-21
UniRef50_Q97XZ7 Cluster: Oxidoreductase; n=6; Thermoprotei|Rep: ... 102 3e-21
UniRef50_P0ABQ3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 101 8e-21
UniRef50_A0GVR3 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 100 1e-20
UniRef50_Q67QX0 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 100 1e-20
UniRef50_Q9A8J9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 99 2e-20
UniRef50_Q183P5 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 99 2e-20
UniRef50_A5V0D4 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 99 2e-20
UniRef50_Q4KH51 Cluster: 3-hydroxyisobutyrate dehydrogenase fami... 100 2e-20
UniRef50_Q930C6 Cluster: Probable; n=8; Alphaproteobacteria|Rep:... 99 3e-20
UniRef50_A0LMG6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=9... 99 3e-20
UniRef50_Q0SBQ9 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 99 4e-20
UniRef50_Q1QWU9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 98 5e-20
UniRef50_Q01ZG6 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 98 7e-20
UniRef50_A3RRS1 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 97 1e-19
UniRef50_A6P2M7 Cluster: Putative uncharacterized protein; n=2; ... 96 2e-19
UniRef50_A2SP40 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 96 3e-19
UniRef50_Q2JEV5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 95 4e-19
UniRef50_Q58PL4 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 95 4e-19
UniRef50_Q41DK0 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 95 4e-19
UniRef50_Q9SUC0 Cluster: Probable 3-hydroxyisobutyrate dehydroge... 95 4e-19
UniRef50_Q92D17 Cluster: Lin1004 protein; n=10; Bacilli|Rep: Lin... 95 5e-19
UniRef50_Q1V2R0 Cluster: MmsB-like protein; n=2; Candidatus Pela... 95 5e-19
UniRef50_Q1QWQ5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 95 5e-19
UniRef50_A0C2T7 Cluster: Chromosome undetermined scaffold_145, w... 95 5e-19
UniRef50_Q4ZQL5 Cluster: 3-hydroxyisobutyrate dehydrogenase prec... 94 1e-18
UniRef50_A0JUJ6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 94 1e-18
UniRef50_Q22B54 Cluster: 3-hydroxyisobutyrate dehydrogenase fami... 94 1e-18
UniRef50_Q03UI4 Cluster: 3-hydroxyisobutyrate dehydrogenase rela... 93 2e-18
UniRef50_A6GTB5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 93 2e-18
UniRef50_Q2UHA9 Cluster: Predicted dehydrogenase; n=16; Pezizomy... 93 2e-18
UniRef50_A1SIN3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 93 3e-18
UniRef50_Q5WBB8 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 92 4e-18
UniRef50_Q11FC5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 92 4e-18
UniRef50_Q89HA0 Cluster: Oxidoreductase; n=1; Bradyrhizobium jap... 92 5e-18
UniRef50_A0LTQ8 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 92 5e-18
UniRef50_A6LT11 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 91 6e-18
UniRef50_Q8KL12 Cluster: Probable 6-phosphogluconate dehydrogena... 91 8e-18
UniRef50_Q18X68 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 91 8e-18
UniRef50_A1B741 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3... 91 8e-18
UniRef50_A5VBF0 Cluster: 2-hydroxy-3-oxopropionate reductase pre... 90 2e-17
UniRef50_Q0UVR9 Cluster: Putative uncharacterized protein; n=1; ... 90 2e-17
UniRef50_Q0LNZ7 Cluster: 3-hydroxyisobutyrate dehydrogenase prec... 89 3e-17
UniRef50_Q39FA8 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 89 3e-17
UniRef50_A3VLN6 Cluster: Oxidoreductase; n=1; Rhodobacterales ba... 89 3e-17
UniRef50_A6SW62 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 89 4e-17
UniRef50_A5GPC0 Cluster: Hydroxyacid dehydrogenase/reductase fam... 89 4e-17
UniRef50_A3SJ77 Cluster: Probable oxidoreductase; n=1; Roseovari... 89 4e-17
UniRef50_Q4Q7T9 Cluster: 2-hydroxy-3-oxopropionate reductase, pu... 89 4e-17
UniRef50_A1UP64 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 88 6e-17
UniRef50_Q0S5S3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 88 8e-17
UniRef50_A5USN9 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 88 8e-17
UniRef50_Q7WCG3 Cluster: Putative uncharacterized protein; n=2; ... 87 1e-16
UniRef50_Q6C351 Cluster: Yarrowia lipolytica chromosome F of str... 87 1e-16
UniRef50_Q4PCH4 Cluster: Putative uncharacterized protein; n=1; ... 87 1e-16
UniRef50_Q8EW87 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 87 1e-16
UniRef50_Q2BFK1 Cluster: Oxidoreductase; n=1; Bacillus sp. NRRL ... 87 1e-16
UniRef50_Q0URA2 Cluster: Putative uncharacterized protein; n=1; ... 87 1e-16
UniRef50_A3H5R1 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 87 1e-16
UniRef50_A0N0V2 Cluster: BtdhL; n=1; Azoarcus anaerobius|Rep: Bt... 87 2e-16
UniRef50_Q5L168 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 86 2e-16
UniRef50_Q0RCX7 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 86 3e-16
UniRef50_Q606G9 Cluster: Oxidoreductase, Gfo/Idh/MocA family; n=... 85 4e-16
UniRef50_A3WAC4 Cluster: Dehydrogenase; n=4; Bacteria|Rep: Dehyd... 85 4e-16
UniRef50_A0FZ96 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 85 5e-16
UniRef50_A3X9R7 Cluster: 3-hydroxyisobutyrate dehydrogenase fami... 85 7e-16
UniRef50_Q0F1Y7 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 84 9e-16
UniRef50_Q01QM2 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 84 1e-15
UniRef50_Q3DYV4 Cluster: NADP oxidoreductase, coenzyme F420-depe... 83 2e-15
UniRef50_A5VEA3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 83 2e-15
UniRef50_Q47AR2 Cluster: NADP oxidoreductase, coenzyme F420-depe... 83 2e-15
UniRef50_Q13LQ9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 83 2e-15
UniRef50_A6SUL3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 83 2e-15
UniRef50_Q1GJB9 Cluster: 6-phosphogluconate dehydrogenase NAD-bi... 82 4e-15
UniRef50_Q89R44 Cluster: Oxidoreductase; n=23; Bacteria|Rep: Oxi... 82 5e-15
UniRef50_Q6UCZ9 Cluster: Predicted oxidoreductase; n=2; environm... 82 5e-15
UniRef50_A1R2J4 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 82 5e-15
UniRef50_Q89UN2 Cluster: Bll1384 protein; n=9; Bacteria|Rep: Bll... 81 7e-15
UniRef50_Q1YHQ4 Cluster: Putative 2-hydroxy-3-oxopropionate redu... 81 7e-15
UniRef50_Q0FFH2 Cluster: Putative 2-hydroxyacid dehydrogenase; n... 81 9e-15
UniRef50_A4SWE8 Cluster: 2-hydroxy-3-oxopropionate reductase pre... 81 9e-15
UniRef50_Q84VC8 Cluster: Gamma hydroxybutyrate dehydrogenase-lik... 81 9e-15
UniRef50_Q94B07 Cluster: Gamma hydroxybutyrate dehydrogenase; n=... 80 2e-14
UniRef50_A7PEG7 Cluster: Chromosome chr11 scaffold_13, whole gen... 80 2e-14
UniRef50_Q39MY1 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 79 3e-14
UniRef50_P77161 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 79 3e-14
UniRef50_Q73P00 Cluster: 3-hydroxyacid dehydrogenase family prot... 79 4e-14
UniRef50_A3WMG5 Cluster: Probable 3-hydroxyisobutyrate dehydroge... 79 4e-14
UniRef50_A3EW86 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 78 6e-14
UniRef50_A0R1N4 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 78 6e-14
UniRef50_Q9LNP0 Cluster: F1L3.35; n=8; Magnoliophyta|Rep: F1L3.3... 78 6e-14
UniRef50_Q13PY3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 78 8e-14
UniRef50_Q7VYY0 Cluster: Putative oxidoreductase; n=4; Bordetell... 77 1e-13
UniRef50_Q1IQE6 Cluster: 2-hydroxy-3-oxopropionate reductase pre... 77 1e-13
UniRef50_A6EH53 Cluster: Putative uncharacterized protein; n=1; ... 77 1e-13
UniRef50_A0G5F9 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 77 1e-13
UniRef50_Q8UBW3 Cluster: Oxidoredutase; n=1; Agrobacterium tumef... 77 1e-13
UniRef50_Q2CHC8 Cluster: Oxidoreductase; n=1; Oceanicola granulo... 77 1e-13
UniRef50_A0NRG5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 77 1e-13
UniRef50_Q0C8I2 Cluster: Predicted protein; n=3; Pezizomycotina|... 77 1e-13
UniRef50_Q830A7 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 77 2e-13
UniRef50_Q5FQ06 Cluster: Putative oxidoreductase; n=1; Gluconoba... 77 2e-13
UniRef50_Q1N6I0 Cluster: Putative oxidoreductase protein; n=1; O... 77 2e-13
UniRef50_A3K497 Cluster: Probable 6-phosphogluconate dehydrogena... 77 2e-13
UniRef50_A0LDJ3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 77 2e-13
UniRef50_A0QUD5 Cluster: 3-hydroxyisobutyrate dehydrogenase fami... 76 3e-13
UniRef50_A1ZWM5 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 76 3e-13
UniRef50_A1UJF2 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 76 3e-13
UniRef50_Q84H84 Cluster: Putative oxidoreductase; n=1; Arthrobac... 75 4e-13
UniRef50_Q3W9L4 Cluster: Putative uncharacterized protein; n=1; ... 75 4e-13
UniRef50_A0JXR2 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 75 6e-13
UniRef50_A0GPK7 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 75 6e-13
UniRef50_A6G049 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 75 8e-13
UniRef50_A3JU55 Cluster: Predicted dehydrogenase, with NAD(P)-bi... 74 1e-12
UniRef50_Q12H32 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 74 1e-12
UniRef50_Q121N3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 74 1e-12
UniRef50_A7IE35 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 74 1e-12
UniRef50_A3LTC4 Cluster: 3-hydroxyisobutyrate dehydrogenase-like... 74 1e-12
UniRef50_A0GI22 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 73 2e-12
UniRef50_Q4Q9Z1 Cluster: Dehydrogenase-like protein; n=6; Trypan... 73 2e-12
UniRef50_Q4WXG9 Cluster: 3-hydroxyisobutyrate dehydrogenase, put... 73 2e-12
UniRef50_Q7NR40 Cluster: Probable 3-hydroxyisobutyrate dehydroge... 73 2e-12
UniRef50_A2C1U6 Cluster: 3-hydroxyisobutyrate dehydrogenase and ... 73 2e-12
UniRef50_Q9JYH6 Cluster: 3-hydroxyacid dehydrogenase; n=5; Prote... 73 3e-12
UniRef50_Q5LQR0 Cluster: 6-phosphogluconate dehydrogenase domain... 73 3e-12
UniRef50_A0G5G5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 73 3e-12
UniRef50_Q8TT25 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 72 5e-12
UniRef50_A1WM48 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 71 7e-12
UniRef50_A1WJN2 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 71 7e-12
UniRef50_Q656T5 Cluster: Oxidoreductase-like; n=3; Oryza sativa|... 71 7e-12
UniRef50_Q7WG50 Cluster: Probable oxidoreductase; n=1; Bordetell... 71 9e-12
UniRef50_Q46TQ0 Cluster: UDP-glucose/GDP-mannose dehydrogenase:P... 71 9e-12
UniRef50_O33730 Cluster: Uncharacterized oxidoreductase Sfri_150... 71 9e-12
UniRef50_Q3W3N3 Cluster: Putative uncharacterized protein; n=1; ... 71 1e-11
UniRef50_A1GFG2 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 71 1e-11
UniRef50_A5FTT0 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 69 3e-11
UniRef50_Q1EPJ1 Cluster: 6-phosphogluconate dehydrogenase NAD-bi... 69 3e-11
UniRef50_Q0BTJ3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 69 4e-11
UniRef50_Q89M84 Cluster: Blr4309 protein; n=6; Bradyrhizobiaceae... 69 5e-11
UniRef50_A0K0Z6 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 69 5e-11
UniRef50_A0K107 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 68 7e-11
UniRef50_A6F020 Cluster: Putative uncharacterized protein; n=1; ... 68 9e-11
UniRef50_Q3W9W7 Cluster: 6-phosphogluconate dehydrogenase, NAD b... 67 1e-10
UniRef50_A5P0V0 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 67 2e-10
UniRef50_O66454 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3... 66 2e-10
UniRef50_Q0KC92 Cluster: 3-Hydroxyisobutyrate dehydrogenase; n=1... 66 2e-10
UniRef50_A7DSF1 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 66 2e-10
UniRef50_A6VLT0 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 66 3e-10
UniRef50_Q9L7S0 Cluster: Uncharacterized oxidoreductase yihU; n=... 66 3e-10
UniRef50_Q019Z7 Cluster: Oxidoreductase-like; n=1; Ostreococcus ... 65 6e-10
UniRef50_A5P600 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 64 8e-10
UniRef50_Q9HLR4 Cluster: Putative uncharacterized protein Ta0161... 64 8e-10
UniRef50_A0YMN9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3... 64 1e-09
UniRef50_A0RU56 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 64 1e-09
UniRef50_P71825 Cluster: Uncharacterized oxidoreductase Rv0770/M... 64 1e-09
UniRef50_Q8PK98 Cluster: 3-hydroxyisobutirate dehydrogenase; n=3... 64 1e-09
UniRef50_Q3WJ00 Cluster: 6-phosphogluconate dehydrogenase, NAD b... 64 1e-09
UniRef50_UPI00015B4162 Cluster: PREDICTED: similar to MGC108315 ... 63 2e-09
UniRef50_Q5LNV6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 63 2e-09
UniRef50_Q9RX16 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=6... 63 3e-09
UniRef50_A7H7Z5 Cluster: 6-phosphogluconate dehydrogenase NAD-bi... 62 3e-09
UniRef50_Q49A26 Cluster: Cytokine-like nuclear factor n-pac; n=4... 62 3e-09
UniRef50_Q20XN2 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 62 4e-09
UniRef50_A6VYD9 Cluster: 2-hydroxy-3-oxopropionate reductase pre... 62 4e-09
UniRef50_Q9LM23 Cluster: Fructose-bisphosphate aldolase; n=2; Ar... 62 4e-09
UniRef50_Q8VYC5 Cluster: Fructose-bisphosphate aldolase; n=12; c... 62 4e-09
UniRef50_Q8U2W2 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 62 4e-09
UniRef50_Q0RIL5 Cluster: Putative uncharacterized protein; n=1; ... 62 6e-09
UniRef50_UPI0000D55E08 Cluster: PREDICTED: similar to CG4747-PA;... 61 8e-09
UniRef50_A4ECY9 Cluster: Putative uncharacterized protein; n=1; ... 61 8e-09
UniRef50_A1UJF3 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 61 8e-09
UniRef50_A0R1N5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 61 8e-09
UniRef50_Q89RT2 Cluster: Bll2680 protein; n=1; Bradyrhizobium ja... 61 1e-08
UniRef50_Q4WV01 Cluster: Oxidoreductase, acting on the CH-OH gro... 60 1e-08
UniRef50_A0JRK4 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 60 2e-08
UniRef50_Q221W9 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 60 2e-08
UniRef50_Q97ZE5 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=4... 60 2e-08
UniRef50_Q98K09 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=7... 59 3e-08
UniRef50_A1CAY2 Cluster: Oxidoreductase, acting on the CH-OH gro... 59 3e-08
UniRef50_A3ET09 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3... 58 5e-08
UniRef50_Q7WNK6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 58 7e-08
UniRef50_Q6F842 Cluster: Putative 3-hydroxyisobutyrate dehydroge... 58 7e-08
UniRef50_Q1GF31 Cluster: 6-phosphogluconate dehydrogenase NAD-bi... 58 7e-08
UniRef50_UPI0001597301 Cluster: YfjR; n=1; Bacillus amyloliquefa... 58 9e-08
UniRef50_Q98I20 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 58 9e-08
UniRef50_Q8F4I7 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=4... 58 9e-08
UniRef50_Q1B326 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 58 9e-08
UniRef50_Q1V2K7 Cluster: NADP oxidoreductase, coenzyme F420-depe... 57 1e-07
UniRef50_Q7NEW9 Cluster: Glr3759 protein; n=3; Bacteria|Rep: Glr... 57 2e-07
UniRef50_Q01PV6 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 57 2e-07
UniRef50_A1WEB7 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 57 2e-07
UniRef50_A5WG80 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 56 2e-07
UniRef50_A4FKN9 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 56 2e-07
UniRef50_A1SQ87 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 56 2e-07
UniRef50_Q74D68 Cluster: 3-hydroxyisobutyrate dehydrogenase fami... 56 3e-07
UniRef50_Q0RMX6 Cluster: Putative reductase; n=1; Frankia alni A... 56 4e-07
UniRef50_A3Y8R5 Cluster: Putative dehydrogenase; n=1; Marinomona... 56 4e-07
UniRef50_A7I8V1 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 55 5e-07
UniRef50_Q1GM24 Cluster: 6-phosphogluconate dehydrogenase NAD-bi... 54 9e-07
UniRef50_Q55W03 Cluster: Putative uncharacterized protein; n=2; ... 54 1e-06
UniRef50_Q89GM2 Cluster: Bll6323 protein; n=6; Proteobacteria|Re... 54 2e-06
UniRef50_A7RG59 Cluster: Predicted protein; n=1; Nematostella ve... 54 2e-06
UniRef50_Q21ZN3 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 53 2e-06
UniRef50_Q120Q9 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 53 3e-06
UniRef50_Q9I1R8 Cluster: Probable dehydrogenase; n=7; Pseudomona... 52 4e-06
UniRef50_A1UDJ6 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 52 4e-06
UniRef50_A0VSV4 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 52 4e-06
UniRef50_Q1NHF5 Cluster: Putative oxidoreductase; n=1; Sphingomo... 52 5e-06
UniRef50_Q033P2 Cluster: 3-hydroxyisobutyrate dehydrogenase rela... 52 5e-06
UniRef50_A5CN67 Cluster: Putative beta-hydroxyacid dehydrogenase... 52 5e-06
UniRef50_A0QZR7 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 52 6e-06
UniRef50_Q21ZT0 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 51 8e-06
UniRef50_A4BV63 Cluster: 3-hydroxyacid dehydrogenase; n=1; Nitro... 51 1e-05
UniRef50_A6RMW8 Cluster: Putative uncharacterized protein; n=2; ... 50 1e-05
UniRef50_Q0W2D7 Cluster: Putative 6-phosphogluconate dehydrogena... 50 1e-05
UniRef50_O34969 Cluster: Uncharacterized oxidoreductase yfjR; n=... 50 1e-05
UniRef50_Q6RXW5 Cluster: Succinic semialdehyde dehydrogenase; n=... 50 2e-05
UniRef50_Q1NHG5 Cluster: Putative uncharacterized protein; n=1; ... 50 2e-05
UniRef50_A3Q3U7 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 50 2e-05
UniRef50_Q8YRT5 Cluster: 3-hydroxyacid dehydrogenase; n=5; Cyano... 49 3e-05
UniRef50_Q5GUM4 Cluster: Dehydrogenase; n=5; Gammaproteobacteria... 49 4e-05
UniRef50_A7DWL2 Cluster: Putative dehydrogenase; n=1; Streptomyc... 49 4e-05
UniRef50_A3ES45 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 49 4e-05
UniRef50_Q0SAG5 Cluster: Phosphogluconate dehydrogenase; n=23; A... 48 6e-05
UniRef50_A6R0U9 Cluster: Predicted protein; n=1; Ajellomyces cap... 48 6e-05
UniRef50_Q9K9H3 Cluster: 6-phosphogluconate dehydrogenase; n=7; ... 48 8e-05
UniRef50_Q13VQ8 Cluster: Putative dehydrogenase/oxidoreductase p... 48 8e-05
UniRef50_A0AWL7 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 48 8e-05
UniRef50_Q39KK8 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 48 1e-04
UniRef50_A3PSD9 Cluster: 6-phosphogluconate dehydrogenase, decar... 48 1e-04
UniRef50_Q4WSB8 Cluster: 6-phosphogluconate dehydrogenase family... 47 2e-04
UniRef50_A7CWR7 Cluster: 6-phosphogluconate dehydrogenase NAD-bi... 46 2e-04
UniRef50_A3PRM1 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 46 2e-04
UniRef50_A4EEN1 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 46 4e-04
UniRef50_A3H9B3 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 45 5e-04
UniRef50_Q19TN0 Cluster: 3-hydroxyisobutyrate dehydrogenase fami... 45 7e-04
UniRef50_Q5MZU3 Cluster: 3-hydroxyacid dehydrogenase; n=3; Cyano... 44 0.001
UniRef50_Q55JR1 Cluster: Putative uncharacterized protein; n=2; ... 44 0.001
UniRef50_A6ELE2 Cluster: 6-phosphogluconate dehydrogenase, decar... 44 0.002
UniRef50_Q392H4 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 43 0.002
UniRef50_A0FZ97 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 43 0.002
UniRef50_Q82ZC2 Cluster: 6-phosphogluconate dehydrogenase family... 43 0.003
UniRef50_A4S5A4 Cluster: Predicted protein; n=2; Ostreococcus|Re... 43 0.003
UniRef50_Q6D9X4 Cluster: Putative 2-hydroxy-3-oxopropionate redu... 42 0.004
UniRef50_UPI0000EBE4FC Cluster: PREDICTED: hypothetical protein;... 42 0.005
UniRef50_Q9RU02 Cluster: 6-phosphogluconate dehydrogenase; n=24;... 42 0.007
UniRef50_Q2JEN4 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 42 0.007
UniRef50_A5GJY3 Cluster: 3-hydroxyisobutyrate dehydrogenase rela... 42 0.007
UniRef50_Q0U6Q6 Cluster: Putative uncharacterized protein; n=5; ... 42 0.007
UniRef50_P80859 Cluster: 6-phosphogluconate dehydrogenase, decar... 41 0.009
UniRef50_Q836Q9 Cluster: 6-phosphogluconate dehydrogenase, decar... 41 0.012
UniRef50_Q2UET7 Cluster: Predicted protein; n=7; Eurotiomycetida... 41 0.012
UniRef50_O66788 Cluster: 6-phosphogluconate dehydrogenase; n=2; ... 40 0.015
UniRef50_Q9CDN4 Cluster: 6-phosphogluconate dehydrogenase; n=12;... 40 0.020
UniRef50_Q5FU44 Cluster: Putative oxidoreductase; n=1; Gluconoba... 40 0.027
UniRef50_Q92P61 Cluster: 6-phosphogluconate dehydrogenase, decar... 39 0.035
UniRef50_Q7TZG1 Cluster: 6-phosphogluconate dehydrogenase, decar... 39 0.035
UniRef50_Q64V77 Cluster: 6-phosphogluconate dehydrogenase, decar... 39 0.047
UniRef50_A4JSC3 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 38 0.081
UniRef50_O32911 Cluster: 6-phosphogluconate dehydrogenase, decar... 38 0.11
UniRef50_P37754 Cluster: 6-phosphogluconate dehydrogenase, decar... 38 0.11
UniRef50_Q8EW86 Cluster: HAD superfamily hydrolase; n=1; Mycopla... 37 0.19
UniRef50_Q629W3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 37 0.19
UniRef50_A3ZZH5 Cluster: Putative uncharacterized protein; n=1; ... 36 0.33
UniRef50_Q0QWD5 Cluster: Putative 3-hydroxyisobutyrate dehydroge... 36 0.33
UniRef50_A5FVG0 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 35 0.57
UniRef50_Q5B0A2 Cluster: Putative uncharacterized protein; n=1; ... 35 0.57
UniRef50_A6T947 Cluster: Putative dehydrogenase; n=1; Klebsiella... 35 0.76
UniRef50_Q1INE9 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 34 1.0
UniRef50_Q1AZK2 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 34 1.0
UniRef50_Q0HQ96 Cluster: CHAP domain containing protein precurso... 33 1.8
UniRef50_P21577 Cluster: 6-phosphogluconate dehydrogenase, decar... 33 1.8
UniRef50_Q4J3S5 Cluster: Ferredoxin; n=1; Azotobacter vinelandii... 33 3.1
UniRef50_Q0F1E8 Cluster: Putative uncharacterized protein; n=1; ... 33 3.1
UniRef50_Q5XXR5 Cluster: Fruitless male-specific zinc-finger C i... 33 3.1
UniRef50_Q6NBP0 Cluster: Possible Major Facilitator Superfamily ... 32 4.0
UniRef50_Q9NJY8 Cluster: Fruitless protein type B; n=1; Drosophi... 32 4.0
UniRef50_A6RQ97 Cluster: Putative uncharacterized protein; n=2; ... 32 4.0
UniRef50_Q1DDR1 Cluster: 6-phosphogluconate dehydrogenase, decar... 32 5.3
UniRef50_A2SJL6 Cluster: ABC type permease; n=2; Proteobacteria|... 32 5.3
UniRef50_UPI00003650C0 Cluster: patched domain containing 3; n=1... 31 7.1
UniRef50_Q3JSX2 Cluster: Putative uncharacterized protein; n=2; ... 31 7.1
UniRef50_Q9RBX6 Cluster: IgiB; n=1; Vogesella indigofera|Rep: Ig... 31 7.1
UniRef50_Q1DAV1 Cluster: Tetratricopeptide repeat protein; n=2; ... 31 7.1
UniRef50_Q176R3 Cluster: Fruitless; n=1; Aedes aegypti|Rep: Frui... 31 7.1
UniRef50_Q2H7Q7 Cluster: Predicted protein; n=1; Chaetomium glob... 31 7.1
UniRef50_A2QBE2 Cluster: Remark: alternate name for S. cerevisia... 31 7.1
UniRef50_P52379 Cluster: Replication origin-binding protein; n=6... 31 7.1
UniRef50_Q6M1N2 Cluster: TRANSPOSASE-fragment; n=19; Corynebacte... 31 9.3
UniRef50_Q10YE8 Cluster: Hemolysin-type calcium-binding region; ... 31 9.3
UniRef50_Q08W95 Cluster: Putative uncharacterized protein; n=1; ... 31 9.3
UniRef50_A5AT06 Cluster: Putative uncharacterized protein; n=1; ... 31 9.3
UniRef50_Q2U7G3 Cluster: Predicted protein; n=1; Aspergillus ory... 31 9.3
>UniRef50_UPI0000D56743 Cluster: PREDICTED: similar to
3-hydroxyisobutyrate dehydrogenase; n=1; Tribolium
castaneum|Rep: PREDICTED: similar to
3-hydroxyisobutyrate dehydrogenase - Tribolium castaneum
Length = 315
Score = 144 bits (348), Expect = 8e-34
Identities = 67/137 (48%), Positives = 90/137 (65%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
V++++L + +V D LG +G++ HA KGSLLID STI P V +++ G F DA
Sbjct: 80 VIITMLPNGDIVKDTVLGTNGILKHASKGSLLIDCSTIQPQVAQEVSKATYSAGFKFLDA 139
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSGGV GA+ TL FM GG K+ + P+L MGA HCG G+GQ+AKL NN+++
Sbjct: 140 PVSGGVTGAEAGTLTFMVGGDKQVLNSADPILMKMGANVLHCGDSGAGQIAKLCNNLILA 199
Query: 361 ITGMATAECMNMGIKMG 411
IT + T E MN+GIKMG
Sbjct: 200 ITMIGTCEGMNLGIKMG 216
>UniRef50_A7UBP6 Cluster: Putative 3-hydroxyisobutyrate
dehydrogenase; n=1; Paracoccus methylutens|Rep: Putative
3-hydroxyisobutyrate dehydrogenase - Paracoccus
methylutens
Length = 302
Score = 133 bits (321), Expect = 2e-30
Identities = 63/136 (46%), Positives = 91/136 (66%)
Frame = +1
Query: 4 VVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 183
V++++ + + VL+++LG DGV+A KGS+ IDSSTID +++ E+G+ DAP
Sbjct: 61 VITMVPTGRHVLEIFLGDDGVLAKMAKGSMAIDSSTIDTADARRLHAAGRERGIAVLDAP 120
Query: 184 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGI 363
VSGGVMGA+ TL FM GG ED ER+ P+L+ MG + FH G+ G GQ AKL NN+L GI
Sbjct: 121 VSGGVMGAEAGTLTFMVGGSAEDLERARPVLEAMGRRIFHAGEPGVGQAAKLCNNLLAGI 180
Query: 364 TGMATAECMNMGIKMG 411
+ +A +E + +G
Sbjct: 181 SMIAVSEAFALARHLG 196
>UniRef50_Q7NWA9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=7;
Proteobacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Chromobacterium violaceum
Length = 296
Score = 132 bits (318), Expect = 4e-30
Identities = 65/137 (47%), Positives = 86/137 (62%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
VV+S+L + K V +YLG +G+ A KG+L+ID STID +++ A EKGL DA
Sbjct: 60 VVISMLPAGKHVAGLYLGDNGLFARLPKGALVIDCSTIDAGTARKVAEGAREKGLSMLDA 119
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSGG GA TL F+ GG ED + P+L+ MG FH G G+GQ AK+ NNML+G
Sbjct: 120 PVSGGTAGAAAGTLTFIVGGAAEDLAHARPVLEAMGKNIFHAGGAGAGQTAKICNNMLLG 179
Query: 361 ITGMATAECMNMGIKMG 411
I TAE + +G+K G
Sbjct: 180 ILMAGTAEALALGVKNG 196
>UniRef50_P31937 Cluster: 3-hydroxyisobutyrate dehydrogenase,
mitochondrial precursor; n=38; Eumetazoa|Rep:
3-hydroxyisobutyrate dehydrogenase, mitochondrial
precursor - Homo sapiens (Human)
Length = 336
Score = 130 bits (315), Expect = 8e-30
Identities = 61/136 (44%), Positives = 92/136 (67%)
Frame = +1
Query: 4 VVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 183
++++L ++ ++ Y G +G++ KKGSLLIDSSTIDP V K++ + G F DAP
Sbjct: 99 IITMLPTSINAIEAYSGANGILKKVKKGSLLIDSSTIDPAVSKELAKEVEKMGAVFMDAP 158
Query: 184 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGI 363
VSGGV A++ L FM GG +++F + LL MG+ +CG +G+GQ AK+ NNML+ I
Sbjct: 159 VSGGVGAARSGNLTFMVGGVEDEFAAAQELLGCMGSNVVYCGAVGTGQAAKICNNMLLAI 218
Query: 364 TGMATAECMNMGIKMG 411
+ + TAE MN+GI++G
Sbjct: 219 SMIGTAEAMNLGIRLG 234
>UniRef50_Q54CX6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3;
cellular organisms|Rep: 3-hydroxyisobutyrate
dehydrogenase - Dictyostelium discoideum AX4
Length = 321
Score = 129 bits (312), Expect = 2e-29
Identities = 59/137 (43%), Positives = 91/137 (66%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
V+V++L ++ V +VY G++G+ + G+LL+DSSTIDP +++ IA + D
Sbjct: 81 VIVTMLPASAHVKNVYCGENGIFQTVRPGTLLLDSSTIDPATAREVASIAKKHQSTMLDC 140
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSGG GA+ TL FM GG ++DF + L+ MG HCG +G+GQVAK+ NN+++G
Sbjct: 141 PVSGGTGGAEAGTLTFMVGGSEQDFNTAKTYLECMGKNIVHCGDVGTGQVAKVCNNLVLG 200
Query: 361 ITGMATAECMNMGIKMG 411
I+ +A +E MN+G+K G
Sbjct: 201 ISMIAVSEAMNLGVKQG 217
>UniRef50_P28811 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=72;
Proteobacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Pseudomonas aeruginosa
Length = 298
Score = 129 bits (312), Expect = 2e-29
Identities = 66/137 (48%), Positives = 88/137 (64%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
VV+S+L + + V +YLG DG++A LLID STI P +++ A KGL DA
Sbjct: 60 VVISMLPAGQHVESLYLGDDGLLARVAGKPLLIDCSTIAPETARKVAEAAAAKGLTLLDA 119
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSGGV GA+ TL+F+ GG E F R+ P+L+ MG FH G G+GQVAK+ NNML+G
Sbjct: 120 PVSGGVGGARAGTLSFIVGGPAEGFARARPVLENMGRNIFHAGDHGAGQVAKICNNMLLG 179
Query: 361 ITGMATAECMNMGIKMG 411
I TAE + +G+K G
Sbjct: 180 ILMAGTAEALALGVKNG 196
>UniRef50_Q399N0 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=72;
cellular organisms|Rep: 3-hydroxyisobutyrate
dehydrogenase - Burkholderia sp. (strain 383)
(Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 /
R18194))
Length = 299
Score = 119 bits (287), Expect = 2e-26
Identities = 61/136 (44%), Positives = 83/136 (61%)
Frame = +1
Query: 4 VVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 183
V+++L + V V G++GV+A G+ +IDSSTIDP + + E G F DAP
Sbjct: 60 VITMLPAAPHVRSVLSGENGVLAGLGAGATVIDSSTIDPASAQAFGALVREHGGAFVDAP 119
Query: 184 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGI 363
VSGG GA TL FM GG DFER P+L MG HCG G GQVAK+ NN+++GI
Sbjct: 120 VSGGTGGAAAGTLTFMVGGSDADFERVKPVLAGMGKNIVHCGATGMGQVAKVCNNLVLGI 179
Query: 364 TGMATAECMNMGIKMG 411
+ A +E M++G+ +G
Sbjct: 180 SMAAVSEAMSLGVALG 195
>UniRef50_Q1AVA4 Cluster: 2-hydroxy-3-oxopropionate reductase; n=6;
Bacteria|Rep: 2-hydroxy-3-oxopropionate reductase -
Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 309
Score = 117 bits (281), Expect = 1e-25
Identities = 57/137 (41%), Positives = 86/137 (62%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
+++++L + V V G+ GV+ ++GSLLID STI P V +Q+ A E+G DA
Sbjct: 74 IIITMLPDSPDVESVVAGEGGVLEGMREGSLLIDMSTISPAVARQLAAKARERGASMLDA 133
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSGG +GA+ TL+ M GG +EDF R+ PL +VMG H G G+GQ+ K N +++G
Sbjct: 134 PVSGGDVGAREGTLSIMVGGSEEDFGRARPLFEVMGKTVTHVGPSGAGQIVKAANQIVVG 193
Query: 361 ITGMATAECMNMGIKMG 411
+T A E + +G++ G
Sbjct: 194 LTIEAVCEALVLGLRGG 210
>UniRef50_A7JGH8 Cluster: Predicted protein; n=1; Francisella
tularensis subsp. novicida GA99-3549|Rep: Predicted
protein - Francisella tularensis subsp. novicida
GA99-3549
Length = 293
Score = 116 bits (279), Expect = 2e-25
Identities = 62/137 (45%), Positives = 82/137 (59%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
+++S+ N+V +V DG++ AK G+++ID+STID N + A + L DA
Sbjct: 61 IILSLPGPNQVS-NVCDSSDGILKIAKAGTIIIDTSTIDANTSVLLAKKAKQNNLHMLDA 119
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSGG++GAQNATL FM GG KE FER L MG K H G G G + KL NNML+G
Sbjct: 120 PVSGGIIGAQNATLTFMVGGDKEIFERCKNLFNSMGKKYLHVGDNGKGLIIKLINNMLLG 179
Query: 361 ITGMATAECMNMGIKMG 411
I +A +E N K G
Sbjct: 180 INMIAASEACNFAEKTG 196
>UniRef50_A6NVP0 Cluster: Putative uncharacterized protein; n=1;
Bacteroides capillosus ATCC 29799|Rep: Putative
uncharacterized protein - Bacteroides capillosus ATCC
29799
Length = 306
Score = 116 bits (278), Expect = 3e-25
Identities = 54/137 (39%), Positives = 80/137 (58%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
V++ L + K+V GK+GV + K+G+++ID S++ PN K + A EKG+ + DA
Sbjct: 64 VIICSLPNAKIVEGTMCGKNGVFENCKEGTVIIDMSSVAPNTTKAMAKKAAEKGIHYIDA 123
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSGGV GA TL M G E F + P+ V+G +H G+ G G K+ NN+L+G
Sbjct: 124 PVSGGVSGAAAGTLTIMVGADDETFNKVKPIFDVLGKNIYHVGEAGGGDAIKMVNNLLLG 183
Query: 361 ITGMATAECMNMGIKMG 411
A AE + +G+K G
Sbjct: 184 CNMAALAEALTLGVKCG 200
>UniRef50_Q9K9L1 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Bacillus|Rep: 3-hydroxyisobutyrate dehydrogenase -
Bacillus halodurans
Length = 299
Score = 113 bits (271), Expect = 2e-24
Identities = 57/129 (44%), Positives = 76/129 (58%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
+V++ L + V+DVY G+DG++A +G +LID ST+D ++ EKG F DA
Sbjct: 61 IVMTCLPLPETVIDVYEGEDGLIAGLSQGKILIDHSTVDRETNVRVAEQIKEKGGAFLDA 120
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSGG MGA+ TL M GG + FERS +L G H G IGSG V KL NNM++G
Sbjct: 121 PVSGGPMGAKAGTLTIMCGGEADSFERSKEVLGAYGDYIVHVGPIGSGTVVKLANNMVIG 180
Query: 361 ITGMATAEC 387
+ EC
Sbjct: 181 VHQAVLGEC 189
>UniRef50_A3I4V2 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Bacillus sp. B14905|Rep: 3-hydroxyisobutyrate
dehydrogenase - Bacillus sp. B14905
Length = 316
Score = 112 bits (269), Expect = 3e-24
Identities = 57/138 (41%), Positives = 88/138 (63%), Gaps = 1/138 (0%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
VV++ L + ++V VYL ++G++ HAKKG+LL+D ST++P++ + A GL + A
Sbjct: 80 VVMTSLPTPQIVEMVYLSEEGIIHHAKKGALLVDFSTVNPDLNDSLHKEASTLGLRYLGA 139
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGS-GQVAKLTNNMLM 357
PVSGGV+GA NATL M GG K+D++ + + ++G +H G S G KL NN+++
Sbjct: 140 PVSGGVIGAVNATLTIMVGGGKDDYDSASEIFGIVGKNIYHLGLSSSVGTRLKLLNNLMI 199
Query: 358 GITGMATAECMNMGIKMG 411
G A AE + +G KMG
Sbjct: 200 GFYTEAVAETIVLGEKMG 217
>UniRef50_Q12CU4 Cluster: 2-hydroxy-3-oxopropionate reductase; n=17;
Proteobacteria|Rep: 2-hydroxy-3-oxopropionate reductase
- Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 298
Score = 110 bits (265), Expect = 1e-23
Identities = 63/137 (45%), Positives = 80/137 (58%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
+VVS+L + VV DV + GV A K GSL +D ++I P + G+ D
Sbjct: 68 IVVSMLENGAVVQDVLFAQ-GVAAAMKPGSLFLDMASITPREARDHAARLGALGIAHLDT 126
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSGG +GA+ TL MAGG+ DFERSLPLLKV G + H G GSGQ+ KL N M++G
Sbjct: 127 PVSGGTVGAEQGTLVIMAGGKPADFERSLPLLKVFG-RATHVGPHGSGQLTKLANQMIVG 185
Query: 361 ITGMATAECMNMGIKMG 411
IT A AE + K G
Sbjct: 186 ITIGAVAEALLFATKGG 202
>UniRef50_Q55702 Cluster: Uncharacterized oxidoreductase slr0229;
n=4; Cyanobacteria|Rep: Uncharacterized oxidoreductase
slr0229 - Synechocystis sp. (strain PCC 6803)
Length = 290
Score = 110 bits (265), Expect = 1e-23
Identities = 56/137 (40%), Positives = 80/137 (58%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
++++ + K V + LG G+ +AK +L+ID STI ++ +GL F DA
Sbjct: 64 IILTCVGDEKDVQQLILGSGGIAEYAKPQALIIDCSTIGKTAAYELATNLKLQGLRFLDA 123
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PV+GG +GA N TL M GG DFE +LP+LK +G K HCG GSGQ KL N +L G
Sbjct: 124 PVTGGDVGAINGTLTIMVGGDISDFEEALPVLKSIGEKIVHCGPSGSGQAVKLCNQVLCG 183
Query: 361 ITGMATAECMNMGIKMG 411
I +A AE + + ++G
Sbjct: 184 IHAIAAAEAIQLSEQLG 200
>UniRef50_Q0K0E2 Cluster: 3-Hydroxyisobutyrate dehydrogenase; n=1;
Ralstonia eutropha H16|Rep: 3-Hydroxyisobutyrate
dehydrogenase - Ralstonia eutropha (strain ATCC 17699 /
H16 / DSM 428 / Stanier 337)(Cupriavidus necator (strain
ATCC 17699 / H16 / DSM 428 / Stanier337))
Length = 299
Score = 109 bits (263), Expect = 2e-23
Identities = 54/137 (39%), Positives = 84/137 (61%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
+V+SI+ + V ++Y GV+ A G+LLI+SSTI P + + A + G DA
Sbjct: 60 IVISIVRNADDVKNLYCTAGGVLDVAAPGALLIESSTIGPAAARAVAAEAAQAGFAMLDA 119
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PV+GG GA+ A L FM GG + F+R+ P+L+ MGA+ F+ G G+GQ+AKL NN++
Sbjct: 120 PVAGGQAGAREARLTFMVGGARTAFDRAEPVLRQMGARIFYAGASGNGQIAKLCNNLIAC 179
Query: 361 ITGMATAECMNMGIKMG 411
++ +E +G K+G
Sbjct: 180 VSSAVVSEAFILGSKLG 196
>UniRef50_Q9V8M5 Cluster: Probable 3-hydroxyisobutyrate
dehydrogenase, mitochondrial precursor; n=4;
Diptera|Rep: Probable 3-hydroxyisobutyrate
dehydrogenase, mitochondrial precursor - Drosophila
melanogaster (Fruit fly)
Length = 324
Score = 109 bits (261), Expect = 3e-23
Identities = 58/138 (42%), Positives = 83/138 (60%), Gaps = 2/138 (1%)
Frame = +1
Query: 4 VVSILTSNKVVLDVY--LGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTD 177
V+++L +N +V Y + DGV K ++ IDSSTI P++ K + KG F D
Sbjct: 88 VITMLPNNAIVDASYDEMTADGV----NKDTIFIDSSTISPDLVKSLQKKISAKGARFID 143
Query: 178 APVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLM 357
APVSGGV GA+ ATL FM GG + ++ +L+ MG K HCG G GQ AKL NNM++
Sbjct: 144 APVSGGVPGAEQATLTFMVGGTEAEYNAVKAVLECMGKKITHCGVYGMGQAAKLCNNMML 203
Query: 358 GITGMATAECMNMGIKMG 411
I+ + +E MN+ ++ G
Sbjct: 204 AISMIGVSEAMNLAVRQG 221
>UniRef50_O34948 Cluster: Uncharacterized oxidoreductase ykwC; n=19;
cellular organisms|Rep: Uncharacterized oxidoreductase
ykwC - Bacillus subtilis
Length = 288
Score = 108 bits (259), Expect = 5e-23
Identities = 56/137 (40%), Positives = 81/137 (59%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
V+++++ V +VY G +G++ +AK+G+ LID +T P++ K+I A EK L DA
Sbjct: 61 VIITMVGYPSDVEEVYFGSNGIIENAKEGAYLIDMTTSKPSLAKKIAEAAKEKALFALDA 120
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSGG +GAQN TLA M GG KE FE +P+ +MG + G GSGQ K+ N + +
Sbjct: 121 PVSGGDIGAQNGTLAIMVGGEKEAFEACMPIFSLMGENIQYQGPAGSGQHTKMCNQIAIA 180
Query: 361 ITGMATAECMNMGIKMG 411
+ AE M K G
Sbjct: 181 AGMIGVAEAMAYAQKSG 197
>UniRef50_Q8ES28 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=13;
Bacillaceae|Rep: 3-hydroxyisobutyrate dehydrogenase -
Oceanobacillus iheyensis
Length = 299
Score = 107 bits (258), Expect = 7e-23
Identities = 53/133 (39%), Positives = 80/133 (60%), Gaps = 1/133 (0%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
V+++ L SNK V VYL K G++ H ++ID+ST+ P + +Q+ E+ + F A
Sbjct: 60 VILTSLPSNKAVEAVYLNKGGLLDHCNSSQVVIDTSTVAPELNQQLEASLSERSIPFLAA 119
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCG-QIGSGQVAKLTNNMLM 357
PVSGGV+GA+N TL M GG++E F++ +L V+G FH G QI G KL NN+L+
Sbjct: 120 PVSGGVVGAENQTLTVMVGGKEETFQKVKDILNVIGGNVFHVGEQIDKGTTVKLINNLLI 179
Query: 358 GITGMATAECMNM 396
G +E + +
Sbjct: 180 GFYTAGVSEALQI 192
>UniRef50_Q4FMJ3 Cluster: 6-phosphogluconate dehydrogenase; n=2;
Candidatus Pelagibacter ubique|Rep: 6-phosphogluconate
dehydrogenase - Pelagibacter ubique
Length = 289
Score = 107 bits (258), Expect = 7e-23
Identities = 53/137 (38%), Positives = 89/137 (64%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
V++++LT + V V +G D +++ K+G+ +ID S+++P + K+ F I EK + + DA
Sbjct: 60 VIITMLTDDAAVEKV-MGSDEFISNIKEGATVIDMSSVNPVITKKYFKILKEKNINYLDA 118
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSGG +GA+ A+LA M GG +E F++ LLK++G G + SGQ++KL N +++G
Sbjct: 119 PVSGGTIGAEEASLAIMVGGDEETFKQCYDLLKILGNPTL-VGPVTSGQISKLANQIIVG 177
Query: 361 ITGMATAECMNMGIKMG 411
+T A AE + + K G
Sbjct: 178 VTIGAVAEAVTLCEKSG 194
>UniRef50_A0UF54 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Burkholderia multivorans ATCC
17616|Rep: 6-phosphogluconate dehydrogenase, NAD-binding
- Burkholderia multivorans ATCC 17616
Length = 289
Score = 107 bits (258), Expect = 7e-23
Identities = 52/130 (40%), Positives = 77/130 (59%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
V++ L ++ +V V LG GV +HAK+G ++ID++T DPN +++ G+GF D
Sbjct: 60 VLILSLPTSAIVEAVVLGDGGVASHAKRGLIVIDTTTADPNSTRKVAAALDAHGIGFIDG 119
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSGG GA AT+ + GG E P+L + AKQ H G G+G V KL NN+L G
Sbjct: 120 PVSGGPKGAATATMTMVLGGADEHIAAVQPVLSAISAKQVHVGPAGAGHVTKLLNNLLTG 179
Query: 361 ITGMATAECM 390
+ + T+E +
Sbjct: 180 VHLLVTSEAV 189
>UniRef50_Q83D20 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=9;
Proteobacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Coxiella burnetii
Length = 297
Score = 106 bits (254), Expect = 2e-22
Identities = 54/137 (39%), Positives = 84/137 (61%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
VV ++L ++ V + L G+ A + ++ IDSS+ID +++ A ++G+ DA
Sbjct: 60 VVFTMLQTSDQVRNCCLSAKGIFATINRQAIYIDSSSIDIEGSRELHKEAKKRGISMLDA 119
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSGGV A+ A L FM GG KEDFER+ +L ++G K + G G+G AK+ NNML+G
Sbjct: 120 PVSGGVAAAEAAGLTFMVGGEKEDFERAKRVLGILGKKIIYAGSDGAGAAAKICNNMLLG 179
Query: 361 ITGMATAECMNMGIKMG 411
I+ +A +E + K+G
Sbjct: 180 ISMIAVSEAFVLADKLG 196
>UniRef50_A1QPH6 Cluster: 3-hydroxyisobutyrate dehydrogenase mmsB;
n=5; Mycobacterium|Rep: 3-hydroxyisobutyrate
dehydrogenase mmsB - Mycobacterium tuberculosis (strain
F11)
Length = 315
Score = 105 bits (253), Expect = 3e-22
Identities = 57/137 (41%), Positives = 82/137 (59%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
VV+++L + +VV Y V+A A+ +L IDSSTI +++ +A G+ DA
Sbjct: 60 VVITMLPTGEVVRRCYTD---VLAAARPATLFIDSSTISVTDAREVHALAESHGMLQLDA 116
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSGGV GA ATLAFM GG + R+ P+L+ M K HCG G+GQ AK+ NNM++
Sbjct: 117 PVSGGVKGAAAATLAFMVGGDESTLRRARPVLEPMAGKIIHCGAAGAGQAAKVCNNMVLA 176
Query: 361 ITGMATAECMNMGIKMG 411
+ +A AE + K+G
Sbjct: 177 VQQIAIAEAFVLAEKLG 193
>UniRef50_Q0QLF5 Cluster: 2-hydroxymethyl glutarate dehydrogenase;
n=1; Eubacterium barkeri|Rep: 2-hydroxymethyl glutarate
dehydrogenase - Eubacterium barkeri (Clostridium
barkeri)
Length = 301
Score = 105 bits (253), Expect = 3e-22
Identities = 48/137 (35%), Positives = 81/137 (59%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
++ + L + +V V G GV++ K G++++D S++ P+ ++ +A EKG+ + DA
Sbjct: 63 IIFTSLPNAGIVETVMNGPGGVLSACKAGTVIVDMSSVSPSSTLKMAKVAAEKGIDYVDA 122
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSGG GA+ TL M G + FE+ P+L V+G +H G G+G K+ NN+L+G
Sbjct: 123 PVSGGTKGAEAGTLTIMVGASEAVFEKIQPVLSVIGKDIYHVGDTGAGDAVKIVNNLLLG 182
Query: 361 ITGMATAECMNMGIKMG 411
+ AE + +G+K G
Sbjct: 183 CNMASLAEALVLGVKCG 199
>UniRef50_P63936 Cluster: Probable 3-hydroxyisobutyrate
dehydrogenase; n=25; Bacteria|Rep: Probable
3-hydroxyisobutyrate dehydrogenase - Mycobacterium bovis
Length = 294
Score = 105 bits (253), Expect = 3e-22
Identities = 57/137 (41%), Positives = 82/137 (59%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
VV+++L + +VV Y V+A A+ +L IDSSTI +++ +A G+ DA
Sbjct: 60 VVITMLPTGEVVRRCYTD---VLAAARPATLFIDSSTISVTDAREVHALAESHGMLQLDA 116
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSGGV GA ATLAFM GG + R+ P+L+ M K HCG G+GQ AK+ NNM++
Sbjct: 117 PVSGGVKGAAAATLAFMVGGDESTLRRARPVLEPMAGKIIHCGAAGAGQAAKVCNNMVLA 176
Query: 361 ITGMATAECMNMGIKMG 411
+ +A AE + K+G
Sbjct: 177 VQQIAIAEAFVLAEKLG 193
>UniRef50_A0QSJ0 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3;
Bacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Length = 290
Score = 104 bits (250), Expect = 6e-22
Identities = 58/137 (42%), Positives = 78/137 (56%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
VV++ L + +V Y V+ A G+L ID+STI + + + ALEKG DA
Sbjct: 60 VVITSLPNGDIVKSCYAE---VLPAAPTGTLFIDTSTISVDDARTVHTQALEKGHAQLDA 116
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSGGV GA TLAFM GG + ER+ P+L M K HCG G+GQ AKL NNM++
Sbjct: 117 PVSGGVKGATAGTLAFMVGGEDDAVERARPILDPMAGKIIHCGGSGTGQAAKLCNNMVLA 176
Query: 361 ITGMATAECMNMGIKMG 411
+ +A E + K+G
Sbjct: 177 VQQIAIGEAFVLAEKLG 193
>UniRef50_A4IN46 Cluster: 3-hydroxyisobutyrate dehydrogenase-like
protein; n=2; Geobacillus|Rep: 3-hydroxyisobutyrate
dehydrogenase-like protein - Geobacillus
thermodenitrificans (strain NG80-2)
Length = 304
Score = 102 bits (244), Expect = 3e-21
Identities = 50/137 (36%), Positives = 81/137 (59%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
V+ + L+ V++VY G+ GV++ A++G + +D +T+ P + + A E+G+ + DA
Sbjct: 60 VICTCLSMPDDVINVYTGEGGVLSAARRGVICLDFTTVGPKTSRFVAGRAGERGVAYLDA 119
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSGG GA+ TL M GG + +ER PLL V+G + G+ G+G AK+ N L+
Sbjct: 120 PVSGGPEGAEQGTLTIMVGGDQAAWERVRPLLSVLGKTVEYLGESGAGSAAKILNQYLVA 179
Query: 361 ITGMATAECMNMGIKMG 411
+ +A AE M G+ G
Sbjct: 180 VHSVAAAEAMVAGVAYG 196
>UniRef50_A2U9T6 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Bacillaceae|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Bacillus coagulans 36D1
Length = 294
Score = 102 bits (244), Expect = 3e-21
Identities = 53/137 (38%), Positives = 80/137 (58%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
V+V++LT+ V +V G+DGV+A KG ++D ST+ P+ + EK F DA
Sbjct: 64 VIVTMLTNAAAVENVLQGEDGVLAGLTKGKTVVDMSTVSPSDSIRFAKWVEEKRGHFIDA 123
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSG V A+ L +AGGRKE+ + P+ +V+G H G+ G G AKL+ N+L+G
Sbjct: 124 PVSGSVQPAKEGNLVILAGGRKEEIDAVRPMFEVLGKTIIHFGENGKGSAAKLSINLLLG 183
Query: 361 ITGMATAECMNMGIKMG 411
+T +E + G K+G
Sbjct: 184 LTIEGASEAILFGEKLG 200
>UniRef50_Q97XZ7 Cluster: Oxidoreductase; n=6; Thermoprotei|Rep:
Oxidoreductase - Sulfolobus solfataricus
Length = 289
Score = 102 bits (244), Expect = 3e-21
Identities = 49/137 (35%), Positives = 79/137 (57%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
+V+S++T V +V G++GVV K+G + +D ST P K++ E G+ F DA
Sbjct: 59 IVISMVTDAPDVEEVLFGENGVVKSNKRGLIFVDMSTNSPEFAKKVTKRLSEYGMEFLDA 118
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PV+GG GA+ TL M GG+++ F+R P+ K MG H G +GSGQ KL N +++
Sbjct: 119 PVTGGDKGAREGTLTIMVGGKEDVFKRVEPIFKAMGKNIIHVGDVGSGQALKLCNQVVVA 178
Query: 361 ITGMATAECMNMGIKMG 411
+ ++ E + + +G
Sbjct: 179 LNMVSVVEGLLLARSLG 195
>UniRef50_P0ABQ3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=25;
Bacteria|Rep: 2-hydroxy-3-oxopropionate reductase -
Escherichia coli O6
Length = 294
Score = 101 bits (241), Expect = 8e-21
Identities = 50/137 (36%), Positives = 81/137 (59%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
V++++L ++ V +V LG++G++ AK G++LID S+I P ++I KG+ DA
Sbjct: 59 VIITMLPNSPHVKEVALGENGIIEGAKPGTVLIDMSSIAPLASREISEALKAKGIDMLDA 118
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSGG A + TL+ M GG K F++ L+K M H G+IG+G V KL N +++
Sbjct: 119 PVSGGEPKAIDGTLSVMVGGDKAIFDKYYDLMKAMAGSVVHTGEIGAGNVTKLANQVIVA 178
Query: 361 ITGMATAECMNMGIKMG 411
+ A +E + + K G
Sbjct: 179 LNIAAMSEALTLATKAG 195
>UniRef50_A0GVR3 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Burkholderia phytofirmans PsJN|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Burkholderia phytofirmans PsJN
Length = 311
Score = 100 bits (240), Expect = 1e-20
Identities = 50/137 (36%), Positives = 79/137 (57%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
+V+++L + V L VY G G+ + +LL++ ST+D +++ A G DA
Sbjct: 59 IVITMLPTPDVSLSVYEGAGGLFSITPPETLLLECSTVDVKTIERLGEGARASGTQLIDA 118
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
P++GG+ GA ATL FM GG +E E + P L+ MG++ H G+ GSG KL NNM+
Sbjct: 119 PLTGGIEGAALATLTFMVGGSEEQLEYARPALQSMGSRIVHAGRFGSGTKLKLVNNMICA 178
Query: 361 ITGMATAECMNMGIKMG 411
M +E + +G+K+G
Sbjct: 179 TNLMVASEALTLGLKLG 195
>UniRef50_Q67QX0 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Symbiobacterium thermophilum|Rep: 3-hydroxyisobutyrate
dehydrogenase - Symbiobacterium thermophilum
Length = 294
Score = 100 bits (239), Expect = 1e-20
Identities = 52/112 (46%), Positives = 66/112 (58%)
Frame = +1
Query: 76 AKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDF 255
A+ G + +D STI K+I + EKG+ F DAPVSGG GA+ TL M GG + F
Sbjct: 83 AQPGDIFVDHSTIGVRDAKRIAAMCAEKGVQFIDAPVSGGPWGAEAGTLTIMCGGDRAAF 142
Query: 256 ERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMG 411
E LP L+V G H G +G+G VAKL NN+L+GI A AE +G K G
Sbjct: 143 EAVLPYLQVEGKAIHHLGPVGAGSVAKLCNNLLVGIHTAAMAEAFVLGTKAG 194
>UniRef50_Q9A8J9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=24;
Alphaproteobacteria|Rep: 3-hydroxyisobutyrate
dehydrogenase - Caulobacter crescentus (Caulobacter
vibrioides)
Length = 298
Score = 99 bits (238), Expect = 2e-20
Identities = 54/137 (39%), Positives = 77/137 (56%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
+V+++L + V VY + ++ +A K +LLID STID + + + A E G F DA
Sbjct: 60 IVITMLPAGPHVRAVYA--EQILPNAPKSALLIDCSTIDVDSARVVARQAAEAGFRFADA 117
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSGG+M A+ TLAFM G DF L M H G G+GQ AK+ NNML+G
Sbjct: 118 PVSGGIMAAEAGTLAFMVGCEASDFAAVEAALAPMSRVTIHAGDHGAGQAAKICNNMLLG 177
Query: 361 ITGMATAECMNMGIKMG 411
++ + T E + K+G
Sbjct: 178 VSMLGTCEAFALAEKLG 194
>UniRef50_Q183P5 Cluster: 2-hydroxy-3-oxopropionate reductase; n=5;
Bacteria|Rep: 2-hydroxy-3-oxopropionate reductase -
Clostridium difficile (strain 630)
Length = 296
Score = 99 bits (238), Expect = 2e-20
Identities = 50/137 (36%), Positives = 78/137 (56%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
+V +IL + +V D+ G DG+ K+GS+++D S++ P + GL F D+
Sbjct: 58 IVFTILPNGTIVQDILFGMDGLAKTLKEGSIVVDMSSVTPTESILCANKLKDMGLEFIDS 117
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSGG A + TLAFMAGG++E +++ P +MG+ G GSG V KLTN +++
Sbjct: 118 PVSGGEPKAIDGTLAFMAGGKEEIYKKVEPFFNIMGSSSILIGDNGSGSVTKLTNQVIVN 177
Query: 361 ITGMATAECMNMGIKMG 411
+T A +E + K G
Sbjct: 178 LTIAAVSEAFVLAAKAG 194
>UniRef50_A5V0D4 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=4; Chloroflexaceae|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Roseiflexus sp. RS-1
Length = 303
Score = 99 bits (238), Expect = 2e-20
Identities = 51/130 (39%), Positives = 75/130 (57%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
++++ ++ V V LG+ GV+ A+ GSL+ID STI P ++I E+ + DA
Sbjct: 63 IIITCVSDTPDVEQVLLGEGGVIHGARPGSLVIDMSTISPRATQRIAAHLAERHIHMLDA 122
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSGG GA TL+ M GG FER+LP+ + MG H G IG+GQ KL N +L+
Sbjct: 123 PVSGGSEGAARGTLSIMVGGDVTQFERALPVFQAMGTTITHLGPIGAGQTTKLVNQILVV 182
Query: 361 ITGMATAECM 390
+A +E +
Sbjct: 183 GHALAMSEAL 192
>UniRef50_Q4KH51 Cluster: 3-hydroxyisobutyrate dehydrogenase family
protein; n=16; Gammaproteobacteria|Rep:
3-hydroxyisobutyrate dehydrogenase family protein -
Pseudomonas fluorescens (strain Pf-5 / ATCC BAA-477)
Length = 298
Score = 99.5 bits (237), Expect = 2e-20
Identities = 47/138 (34%), Positives = 79/138 (57%), Gaps = 1/138 (0%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFP-IALEKGLGFTD 177
+++ L + +VV +V G G+ A+ G LL+D S+++P +++ +A +G+ + D
Sbjct: 64 LMLMCLANTEVVREVVFGPQGIAQGARAGQLLLDLSSLEPTATREMAAELAASRGVAWVD 123
Query: 178 APVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLM 357
APVSGG GA+ +LA M GG D ER P+L +G + H G +G+GQV K N M++
Sbjct: 124 APVSGGTPGAEAGSLAIMVGGEATDVERVRPVLLTLGQRVTHMGAVGAGQVTKACNQMIV 183
Query: 358 GITGMATAECMNMGIKMG 411
+ AE + + + G
Sbjct: 184 ACNALVIAEVVALAERSG 201
>UniRef50_Q930C6 Cluster: Probable; n=8; Alphaproteobacteria|Rep:
Probable - Rhizobium meliloti (Sinorhizobium meliloti)
Length = 295
Score = 99.1 bits (236), Expect = 3e-20
Identities = 51/136 (37%), Positives = 76/136 (55%)
Frame = +1
Query: 4 VVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 183
V+ L + +V G GV A A+ G+L+ID S+IDPN KQ+ A EKGL + D+P
Sbjct: 62 VILSLNAPAIVRQAVFGDAGVAAGAQAGTLIIDMSSIDPNATKQLAADAAEKGLRWVDSP 121
Query: 184 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGI 363
+SGG A L MAGG +D + + +L+ + + H G +G+GQ KL N +L G+
Sbjct: 122 LSGGAPKALIGELTLMAGGTAQDVKDAHAVLRHVASNYTHMGSVGAGQTTKLINQVLCGL 181
Query: 364 TGMATAECMNMGIKMG 411
+A AE + + G
Sbjct: 182 GFLAVAEATQLALDAG 197
>UniRef50_A0LMG6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=9;
cellular organisms|Rep: 3-hydroxyisobutyrate
dehydrogenase - Syntrophobacter fumaroxidans (strain DSM
10017 / MPOB)
Length = 309
Score = 99.1 bits (236), Expect = 3e-20
Identities = 51/137 (37%), Positives = 83/137 (60%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
VV ++L + V +VY G++G++ A+ G +L+D +T +P++ ++I A E+G DA
Sbjct: 72 VVFTMLGFPQDVREVYFGRNGLLQAARPGIILVDMTTTEPSLAREIHQAAGEQGAFAVDA 131
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSGG +GA+NA L+ M GG +E + P+L+ MG + G GSGQ AK+ N +++
Sbjct: 132 PVSGGDVGARNAALSIMLGGDREVVDAIRPILEAMGKNLVYLGPAGSGQHAKVCNQIVIT 191
Query: 361 ITGMATAECMNMGIKMG 411
T + E + G K G
Sbjct: 192 GTMIGVCESLMYGFKAG 208
>UniRef50_Q0SBQ9 Cluster: 2-hydroxy-3-oxopropionate reductase; n=12;
Actinomycetales|Rep: 2-hydroxy-3-oxopropionate reductase
- Rhodococcus sp. (strain RHA1)
Length = 294
Score = 98.7 bits (235), Expect = 4e-20
Identities = 51/119 (42%), Positives = 68/119 (57%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
VV ++ + V V G+DGV H G+L+ID S+I P+V + A E+G DA
Sbjct: 60 VVAVMVPDSPDVQAVLTGEDGVFEHTPSGALIIDFSSIRPDVTTALAAQATERGFRLIDA 119
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLM 357
PVSGG GA NA L+ M GG EDFE + P+L V+G H G GSGQ K N +++
Sbjct: 120 PVSGGEAGAVNAALSIMVGGAPEDFESARPILDVVGKTVVHVGPNGSGQTVKAANQLIV 178
>UniRef50_Q1QWU9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Chromohalobacter salexigens DSM 3043|Rep:
3-hydroxyisobutyrate dehydrogenase - Chromohalobacter
salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB13768)
Length = 310
Score = 98.3 bits (234), Expect = 5e-20
Identities = 50/132 (37%), Positives = 73/132 (55%)
Frame = +1
Query: 16 LTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGG 195
L ++ V +V G++ A KGS+++D+ST DP V +++ +E GL + DAPVSGG
Sbjct: 72 LPTSAHVREVIETSPGLLQRAPKGSVIVDTSTSDPAVTRELAGKVVEAGLEWLDAPVSGG 131
Query: 196 VMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMA 375
GA + L + GG ER P+L+ M A+ H G GSG V KL NN L +
Sbjct: 132 PAGAASGALGMLLGGESATIERLAPMLEAMSARHTHVGPAGSGHVVKLANNYLCAAHLLT 191
Query: 376 TAECMNMGIKMG 411
TAE + + + G
Sbjct: 192 TAEAVTLAARAG 203
>UniRef50_Q01ZG6 Cluster: 2-hydroxy-3-oxopropionate reductase; n=6;
Bacteria|Rep: 2-hydroxy-3-oxopropionate reductase -
Solibacter usitatus (strain Ellin6076)
Length = 298
Score = 97.9 bits (233), Expect = 7e-20
Identities = 52/137 (37%), Positives = 76/137 (55%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
+V+++L V LG GV+ AK G++++D S+I P V +++ KG+ F DA
Sbjct: 60 IVITMLPDGPEVETAVLGPGGVLEGAKAGTVVVDMSSISPMVSQKVAAACAAKGVEFLDA 119
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSGG A + TLA M GG+ E FER P+L MGA G +G+G V KL N +++
Sbjct: 120 PVSGGEPKAIDGTLAIMVGGKPEVFERVQPVLAKMGASVTLTGAVGAGNVTKLANQIMVA 179
Query: 361 ITGMATAECMNMGIKMG 411
A E + + K G
Sbjct: 180 CNIAAMGEALVLATKAG 196
>UniRef50_A3RRS1 Cluster: 2-hydroxy-3-oxopropionate reductase; n=11;
Betaproteobacteria|Rep: 2-hydroxy-3-oxopropionate
reductase - Ralstonia solanacearum UW551
Length = 298
Score = 97.1 bits (231), Expect = 1e-19
Identities = 59/134 (44%), Positives = 75/134 (55%), Gaps = 4/134 (2%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKG----SLLIDSSTIDPNVPKQIFPIALEKGLG 168
VV + +TS V V LG DGV+ A +G ++ ID STI ++I GL
Sbjct: 60 VVFTNVTSTADVEAVLLGPDGVIHGAPRGKPGSAVCIDHSTISAVATRRIAAELETAGLD 119
Query: 169 FTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNN 348
F DAPVSGG MGAQ ATL+ M GG+ E ER PLL+++G H G G+GQVAK N
Sbjct: 120 FLDAPVSGGTMGAQKATLSIMVGGKAEVLERVRPLLQLLGTTITHIGDHGAGQVAKACNQ 179
Query: 349 MLMGITGMATAECM 390
++ I AE M
Sbjct: 180 IVQVINIQGIAEAM 193
>UniRef50_A6P2M7 Cluster: Putative uncharacterized protein; n=2;
Bacteria|Rep: Putative uncharacterized protein -
Bacteroides capillosus ATCC 29799
Length = 321
Score = 96.3 bits (229), Expect = 2e-19
Identities = 51/128 (39%), Positives = 75/128 (58%)
Frame = +1
Query: 4 VVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 183
V SI+ K V +VY G G++++A+ G+L++D +T P + ++I+ KGL DAP
Sbjct: 95 VFSIVGYPKDVEEVYFGDGGIISNAQPGALIVDMTTSSPALAERIWEAGKAKGLRPLDAP 154
Query: 184 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGI 363
V+GG GA+ TL+ + GG K DF+ LPL + MG H G G+GQ AKL N + I
Sbjct: 155 VTGGDTGAKAGTLSILVGGDKVDFDACLPLFQAMGKIIVHMGSAGAGQHAKLANQ--IAI 212
Query: 364 TGMATAEC 387
G + C
Sbjct: 213 AGALSGVC 220
>UniRef50_A2SP40 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Methylibium petroleiphilum PM1|Rep: 3-hydroxyisobutyrate
dehydrogenase - Methylibium petroleiphilum (strain PM1)
Length = 297
Score = 95.9 bits (228), Expect = 3e-19
Identities = 56/138 (40%), Positives = 79/138 (57%), Gaps = 1/138 (0%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
VVV+ L + +V DVYLGK G+VA A+ GS LI++STIDPN +++ A + G+ D
Sbjct: 60 VVVTSLPNPPIVRDVYLGKQGLVAQARPGSTLIETSTIDPNTIREVAQAATKSGIRILDI 119
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
+SG A L F GG E ++ L LL+V+ K G IG+ + KL NN LM
Sbjct: 120 ALSGEPPQAVLGELVFQVGGPDELIDQHLELLQVLAKKINRTGGIGTAKTVKLVNN-LMS 178
Query: 361 ITGMA-TAECMNMGIKMG 411
+ +A AE +G+K G
Sbjct: 179 LGNVAVAAEAFVLGVKCG 196
>UniRef50_Q2JEV5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=6; Bacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Frankia sp. (strain CcI3)
Length = 302
Score = 95.5 bits (227), Expect = 4e-19
Identities = 50/137 (36%), Positives = 74/137 (54%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
VV + ++ V +V LG DGV+ + G++++D +T + ++I E G+GF DA
Sbjct: 60 VVCLCVGADDDVREVVLGADGVLGALRPGAIIVDHTTTSAELAEEIAARTAEVGVGFVDA 119
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSGG GA L+ M GG E ER+ P+L GA G +GSGQ+ K+ N +L+
Sbjct: 120 PVSGGEAGAMAGRLSIMCGGDPETIERARPVLAAYGATITRIGPVGSGQLTKMVNQILVA 179
Query: 361 ITGMATAECMNMGIKMG 411
AE +N I G
Sbjct: 180 GAVEGAAEAINFAIAAG 196
>UniRef50_Q58PL4 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
uncultured proteobacterium DelRiverFos06H03|Rep:
3-hydroxyisobutyrate dehydrogenase - uncultured
proteobacterium DelRiverFos06H03
Length = 299
Score = 95.5 bits (227), Expect = 4e-19
Identities = 50/137 (36%), Positives = 78/137 (56%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
VV++ L V +V LG+ GV+AH K G+ +ID+ST + +++ +A KG+ F +A
Sbjct: 64 VVMASLPGPVQVREVMLGEQGVLAHVKAGATVIDTSTSAVELVQELVALAKSKGVDFLEA 123
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PV+ V A L+ GG K+ FE+ P+ V+G K FH G+ G+G KL N+L
Sbjct: 124 PVTNAVDMAALGRLSIFVGGDKDCFEKHKPIFDVIGEKIFHVGEPGNGATIKLLTNLLWF 183
Query: 361 ITGMATAECMNMGIKMG 411
++ A E + +G K G
Sbjct: 184 VSAAAIGEGLMLGAKAG 200
>UniRef50_Q41DK0 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Bacillaceae|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Exiguobacterium sibiricum
255-15
Length = 293
Score = 95.5 bits (227), Expect = 4e-19
Identities = 52/137 (37%), Positives = 79/137 (57%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
VV+SI+ + V ++YL +DG++A A G+++ID +T P + +I A + GL DA
Sbjct: 61 VVISIVGYPQDVEEIYLAEDGILASANPGTIVIDMTTSSPALAIRIAEQAAQTGLHALDA 120
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PV+GG +GA+N TLA + GG + F+ PL + MG G G GQ AKL N + +
Sbjct: 121 PVTGGDLGAKNGTLAILVGGEEAAFDTVKPLFEAMGKSIARFGGPGQGQSAKLANQIAIA 180
Query: 361 ITGMATAECMNMGIKMG 411
+ + TAE + K G
Sbjct: 181 GSMIGTAEMLLFVTKSG 197
>UniRef50_Q9SUC0 Cluster: Probable 3-hydroxyisobutyrate
dehydrogenase, mitochondrial precursor; n=13;
Magnoliophyta|Rep: Probable 3-hydroxyisobutyrate
dehydrogenase, mitochondrial precursor - Arabidopsis
thaliana (Mouse-ear cress)
Length = 347
Score = 95.5 bits (227), Expect = 4e-19
Identities = 53/149 (35%), Positives = 84/149 (56%), Gaps = 12/149 (8%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAK--KGSLLIDSSTIDPNVPKQIFPIALEKGLG-- 168
VV+++L S+ V+DVY G +G++ + +L IDSSTIDP ++I L
Sbjct: 96 VVITMLPSSSHVMDVYTGTNGLLLGENDIRPALFIDSSTIDPQTTRKISLAVSNCNLKEK 155
Query: 169 --------FTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSG 324
DAPVSGGV+ A+ TL FM GG ++ + + P+L+ MG +CG G+G
Sbjct: 156 RDNWEKPVMLDAPVSGGVLAAEAGTLTFMVGGPEDAYLAARPILQSMGRTSIYCGGSGNG 215
Query: 325 QVAKLTNNMLMGITGMATAECMNMGIKMG 411
AK+ NN+ M ++ + T+E + +G +G
Sbjct: 216 SAAKICNNLAMAVSMLGTSEALALGQSLG 244
>UniRef50_Q92D17 Cluster: Lin1004 protein; n=10; Bacilli|Rep:
Lin1004 protein - Listeria innocua
Length = 286
Score = 95.1 bits (226), Expect = 5e-19
Identities = 47/130 (36%), Positives = 77/130 (59%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
+++S++ K V +YLG++G + + K GS+ ID +T P + K+I EKG+G DA
Sbjct: 60 ILISMVGYPKDVEQLYLGENGFLDNLKAGSVAIDMTTSSPALAKKIAEAGHEKGIGVLDA 119
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSGG +GA+N TLA M GG ++ F + P+ +++G+ G GSGQ K+ N + +
Sbjct: 120 PVSGGDIGAKNGTLAIMVGGAEDVFLKVKPIFEILGSSVILQGDAGSGQHTKMVNQIAIA 179
Query: 361 ITGMATAECM 390
+ E +
Sbjct: 180 SNMIGVTEAI 189
>UniRef50_Q1V2R0 Cluster: MmsB-like protein; n=2; Candidatus
Pelagibacter ubique|Rep: MmsB-like protein - Candidatus
Pelagibacter ubique HTCC1002
Length = 308
Score = 95.1 bits (226), Expect = 5e-19
Identities = 51/135 (37%), Positives = 76/135 (56%)
Frame = +1
Query: 4 VVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 183
V+S+L K V +YLG G++ K L+ID STID ++ + + G+ DAP
Sbjct: 62 VISMLPEGKHVRSLYLGDKGILNKIPKECLIIDCSTIDIETSLELGNESKKLGIKMIDAP 121
Query: 184 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGI 363
V+GGVMGA+ L F+ GG E + PL +MG K H G GSG K+ NNM +GI
Sbjct: 122 VTGGVMGARIGKLNFLVGGSDEAVALAKPLFDIMGQKILHAGVQGSGVGVKICNNMSLGI 181
Query: 364 TGMATAECMNMGIKM 408
+ +A +E + + ++
Sbjct: 182 SMIAASESLMLAKRL 196
>UniRef50_Q1QWQ5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=4; Proteobacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Chromohalobacter salexigens
(strain DSM 3043 / ATCC BAA-138 / NCIMB13768)
Length = 315
Score = 95.1 bits (226), Expect = 5e-19
Identities = 53/137 (38%), Positives = 77/137 (56%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
+VV +L+S V D+ LG +GV+AH + L+ S+I + ++ A +G+G+ DA
Sbjct: 82 IVVVMLSSGPVCDDILLGPEGVIAHMAPHATLVVMSSIPVDTAQRQAQAAEARGIGYLDA 141
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSGG GA + TLA M GG FER PL +G + H G GSGQ+AKL N ++
Sbjct: 142 PVSGGERGAIDGTLAIMVGGDPATFERHRPLFAPLG-RAVHVGPAGSGQLAKLANQSIVA 200
Query: 361 ITGMATAECMNMGIKMG 411
T AE + + + G
Sbjct: 201 NTIATVAEALLLAERGG 217
>UniRef50_A0C2T7 Cluster: Chromosome undetermined scaffold_145,
whole genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_145,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 299
Score = 95.1 bits (226), Expect = 5e-19
Identities = 51/136 (37%), Positives = 80/136 (58%)
Frame = +1
Query: 4 VVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 183
++++L ++K+V V + +KK +LIDSSTI P ++ +A + + DAP
Sbjct: 70 IITMLPNDKIVKSV---AQEIFKKSKK--ILIDSSTISPYTSYELAKMAQDTQNIYADAP 124
Query: 184 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGI 363
VSG V A+ T+ FM G KE +E+ P+LK MG F+CG+IG GQ+AK+ NM + I
Sbjct: 125 VSGSVSEAKLGTITFMVGAEKELYEKISPILKEMGKNIFNCGKIGEGQIAKMCGNMALAI 184
Query: 364 TGMATAECMNMGIKMG 411
++ E + +G MG
Sbjct: 185 QMISVCEALALGKNMG 200
>UniRef50_Q4ZQL5 Cluster: 3-hydroxyisobutyrate dehydrogenase
precursor; n=11; Proteobacteria|Rep:
3-hydroxyisobutyrate dehydrogenase precursor -
Pseudomonas syringae pv. syringae (strain B728a)
Length = 296
Score = 93.9 bits (223), Expect = 1e-18
Identities = 45/137 (32%), Positives = 77/137 (56%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
+++ L + V V LG G+ +KG +++D++T P + +++ + G+ F DA
Sbjct: 61 ILILSLPKAEHVESVCLGAGGINEVGRKGLIVVDTTTSTPEMSRKVAAELAKNGIAFIDA 120
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSGG GA +++ + G D R++P+L+ M + H GQ G+G VAK+ NNML
Sbjct: 121 PVSGGPKGAATGSMSMVIGAEDADLARAMPVLEGMSGTRVHVGQCGAGNVAKIANNMLAA 180
Query: 361 ITGMATAECMNMGIKMG 411
++TAE + M + G
Sbjct: 181 CHLISTAEAVAMAARAG 197
>UniRef50_A0JUJ6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Micrococcineae|Rep: 3-hydroxyisobutyrate dehydrogenase -
Arthrobacter sp. (strain FB24)
Length = 300
Score = 93.9 bits (223), Expect = 1e-18
Identities = 52/137 (37%), Positives = 77/137 (56%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
VV ++L + VYLG+DGV+AHA + +LL+DSSTID + + A G F DA
Sbjct: 60 VVFTMLPKGEHARAVYLGEDGVLAHADRRTLLVDSSTIDIASAQALHDAAAAAGFRFVDA 119
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSGG+ GA+ TL FM GG + ++ M + G +GQ AK+ NN+++
Sbjct: 120 PVSGGMSGAKAGTLTFMIGGDAGAVAEATEYIRPMASNIIPTGGPTTGQAAKICNNLMLF 179
Query: 361 ITGMATAECMNMGIKMG 411
I +TAE + ++G
Sbjct: 180 INLASTAEGAVLAERLG 196
>UniRef50_Q22B54 Cluster: 3-hydroxyisobutyrate dehydrogenase family
protein; n=1; Tetrahymena thermophila SB210|Rep:
3-hydroxyisobutyrate dehydrogenase family protein -
Tetrahymena thermophila SB210
Length = 316
Score = 93.9 bits (223), Expect = 1e-18
Identities = 54/136 (39%), Positives = 80/136 (58%), Gaps = 1/136 (0%)
Frame = +1
Query: 7 VSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 186
V++L ++ V V G++G+ + K SL IDSSTI + +I+ A + + DAPV
Sbjct: 78 VTMLPNSSHVSSVLEGENGLFQKSAKNSLFIDSSTISYHAAIKIYENAKKVNQRYIDAPV 137
Query: 187 SGGVMGAQNATLAFMAGG-RKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGI 363
SGGV A TL FM G KE F+ LL+ MG +C + G+G +AK+ NNM +GI
Sbjct: 138 SGGVGAATAGTLTFMVGAENKELFQECKNLLQHMGKNIANCEKPGAGSIAKICNNMALGI 197
Query: 364 TGMATAECMNMGIKMG 411
+A AE +++G K+G
Sbjct: 198 EMIAVAEAISLGKKLG 213
>UniRef50_Q03UI4 Cluster: 3-hydroxyisobutyrate dehydrogenase related
enzyme; n=2; Lactobacillales|Rep: 3-hydroxyisobutyrate
dehydrogenase related enzyme - Leuconostoc mesenteroides
subsp. mesenteroides (strain ATCC 8293 /NCDO 523)
Length = 287
Score = 93.5 bits (222), Expect = 2e-18
Identities = 47/121 (38%), Positives = 72/121 (59%)
Frame = +1
Query: 28 KVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGA 207
K V +V+ +DGV A AK+GS+L+D +T P + +Q+ + G DAPVSGG +GA
Sbjct: 68 KDVEEVWTSEDGVFAGAKEGSILVDMTTSTPRLAEQLAQTGADLGFKVLDAPVSGGDIGA 127
Query: 208 QNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAEC 387
+N TLA M GG ++ + P+L V+G + G G GQ K++NN+ + T + AE
Sbjct: 128 KNGTLAIMVGGEQQVLDEIKPVLSVIGQQIVFAGSAGKGQHMKMSNNIGVAATVITMAES 187
Query: 388 M 390
+
Sbjct: 188 L 188
>UniRef50_A6GTB5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding protein; n=1; Limnobacter sp. MED105|Rep:
6-phosphogluconate dehydrogenase, NAD-binding protein -
Limnobacter sp. MED105
Length = 299
Score = 93.1 bits (221), Expect = 2e-18
Identities = 52/137 (37%), Positives = 75/137 (54%), Gaps = 1/137 (0%)
Frame = +1
Query: 4 VVSILTSNKVVLDVYLGKDGVVA-HAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
+V++ +N + L +DG +A HA+ GS+++D STID I +G+ + D
Sbjct: 67 LVALNVTNTADVQSLLFRDGGIAQHAQPGSIIVDFSTIDAAAVADIARQLKSRGVDYIDC 126
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSGG GA+ ATL+ MAGG F R P+LK +G H G G+GQ K N M +
Sbjct: 127 PVSGGAAGARAATLSMMAGGDLAAFNRIEPMLKHLGKTIRHVGPSGAGQAIKAANQMALC 186
Query: 361 ITGMATAECMNMGIKMG 411
I + AE MN ++ G
Sbjct: 187 IQLVGIAEAMNYALEQG 203
>UniRef50_Q2UHA9 Cluster: Predicted dehydrogenase; n=16;
Pezizomycotina|Rep: Predicted dehydrogenase -
Aspergillus oryzae
Length = 363
Score = 93.1 bits (221), Expect = 2e-18
Identities = 58/143 (40%), Positives = 83/143 (58%), Gaps = 6/143 (4%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVY--LGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLG-F 171
V+V+ L + V +V+ + + G + +K L ID+STIDP ++I G F
Sbjct: 118 VIVTSLPEPEHVKNVFYCMLRHGELPALEKERLFIDTSTIDPASSREIANAIHTTRQGRF 177
Query: 172 TDAPVSGGVMGAQNATLAFMAGGRKEDFE---RSLPLLKVMGAKQFHCGQIGSGQVAKLT 342
DAP+SGGV+GA+ TL+FM G + E R +L +MG K +H G G+G AKL
Sbjct: 178 VDAPMSGGVVGARAGTLSFMFGASSQTGELVDRVQSVLMLMGKKAWHMGNSGTGVSAKLA 237
Query: 343 NNMLMGITGMATAECMNMGIKMG 411
NN L+ I +ATAE MN+GI+ G
Sbjct: 238 NNYLLAINNIATAEVMNLGIRCG 260
>UniRef50_A1SIN3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Nocardioides sp. JS614|Rep: 3-hydroxyisobutyrate
dehydrogenase - Nocardioides sp. (strain BAA-499 /
JS614)
Length = 308
Score = 92.7 bits (220), Expect = 3e-18
Identities = 52/140 (37%), Positives = 77/140 (55%), Gaps = 3/140 (2%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLG---KDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGF 171
VV+++L + ++ V LG + GV+ + G+L+IDSS+ID + A G+ F
Sbjct: 60 VVITMLPNGDILRQVLLGAGAESGVLNYLAPGALVIDSSSIDVANCLAVHESAASAGIAF 119
Query: 172 TDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNM 351
DAPVSGGV GA TL FM GG + R+ PL + MG K G +GQ K+ N M
Sbjct: 120 LDAPVSGGVGGAAAGTLTFMVGGDEAHVRRAWPLFEAMGKKVVRVGGPSTGQAVKMCNQM 179
Query: 352 LMGITGMATAECMNMGIKMG 411
+ + +A AE ++ K+G
Sbjct: 180 IYASSLVAVAEAFSLADKLG 199
>UniRef50_Q5WBB8 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Bacillus clausii KSM-K16|Rep: 3-hydroxyisobutyrate
dehydrogenase - Bacillus clausii (strain KSM-K16)
Length = 283
Score = 92.3 bits (219), Expect = 4e-18
Identities = 50/122 (40%), Positives = 66/122 (54%), Gaps = 1/122 (0%)
Frame = +1
Query: 4 VVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 183
V+ L S +V D GK+GV+ H + G L+D ST D + A KG+ + D P
Sbjct: 61 VLLSLPSPNIVADTVAGKEGVLCHLQTGGFLLDLSTTDVQTTLAMEKAAAAKGIYYLDCP 120
Query: 184 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLM-G 360
VSGG GA TL M GG K+ + PLL ++G + G G+GQ KL NNML+ G
Sbjct: 121 VSGGPAGADAGTLTIMVGGDKQAYFSVKPLLDILGDTILYVGDSGAGQTVKLCNNMLVAG 180
Query: 361 IT 366
IT
Sbjct: 181 IT 182
>UniRef50_Q11FC5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Rhizobiales|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Mesorhizobium sp. (strain
BNC1)
Length = 292
Score = 92.3 bits (219), Expect = 4e-18
Identities = 50/128 (39%), Positives = 71/128 (55%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
VVV++L V V LG+DG+ G+L+ID STI + + I +G+ DA
Sbjct: 60 VVVTMLPDTPHVQSVLLGEDGIGTLLPTGTLVIDMSTISASGIRAIGQDLASRGVDLVDA 119
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSGGV GA L+ M GG E F ++ P+L+ MG H G +G GQV K+ N +++G
Sbjct: 120 PVSGGVRGAIAGELSIMCGGSPEAFAKARPVLEGMGTTIIHAGDLGMGQVFKMCNQLMVG 179
Query: 361 ITGMATAE 384
+ A E
Sbjct: 180 VHIQAMCE 187
>UniRef50_Q89HA0 Cluster: Oxidoreductase; n=1; Bradyrhizobium
japonicum|Rep: Oxidoreductase - Bradyrhizobium japonicum
Length = 313
Score = 91.9 bits (218), Expect = 5e-18
Identities = 48/138 (34%), Positives = 70/138 (50%), Gaps = 1/138 (0%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFP-IALEKGLGFTD 177
+V +T V +V G +G+ G L++D S+I P+ + + + G G+ D
Sbjct: 82 IVFMCVTDAAAVEEVIFGAEGLSTAPGAGKLVVDFSSIHPDAARDLATRLKAANGAGWID 141
Query: 178 APVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLM 357
APVSGG GA+ TLA MAGG D ER P + M + H G G+GQ AKL N +++
Sbjct: 142 APVSGGTKGAEEGTLAIMAGGDASDIERVRPYVLTMARRFTHMGPTGAGQTAKLCNQVIV 201
Query: 358 GITGMATAECMNMGIKMG 411
G AE + + G
Sbjct: 202 GCAMAVLAEATRLAVNAG 219
>UniRef50_A0LTQ8 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=1; Acidothermus cellulolyticus
11B|Rep: 6-phosphogluconate dehydrogenase, NAD-binding
precursor - Acidothermus cellulolyticus (strain ATCC
43068 / 11B)
Length = 305
Score = 91.9 bits (218), Expect = 5e-18
Identities = 49/137 (35%), Positives = 72/137 (52%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
V ++ L + V DV+LG DGVVA A+ G ++ + ST++P V + I P KG D
Sbjct: 61 VALTSLADRRAVEDVFLGPDGVVAGARPGLVVAELSTVEPEVARAIAPELRAKGADILDV 120
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSG V A+ L M GG + P+L ++G + FH G +GSG KL N ++
Sbjct: 121 PVSGSVAVAREGGLTLMVGGEDASLDAIRPVLDIIGRRIFHLGPLGSGAAMKLAVNTVIH 180
Query: 361 ITGMATAECMNMGIKMG 411
A AE + + + G
Sbjct: 181 GLNAALAEGLVLAERAG 197
>UniRef50_A6LT11 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Clostridiales|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Clostridium beijerinckii
NCIMB 8052
Length = 291
Score = 91.5 bits (217), Expect = 6e-18
Identities = 49/136 (36%), Positives = 81/136 (59%), Gaps = 2/136 (1%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
V+++I+ K V +VY G++G++ +AKK S +ID +T P + +I+ A ++ + DA
Sbjct: 60 VIITIVGYPKDVEEVYFGENGILENAKKESCIIDMTTTSPKLSIKIYNEAKKREIYALDA 119
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLM- 357
PVSGG +GA+NATL+ M GG E FE+ +L +G + G+ G+GQ K+ N + +
Sbjct: 120 PVSGGDVGAKNATLSIMVGGDLEVFEKHKDVLSALGTNIIYEGKAGNGQHTKMANQIALA 179
Query: 358 -GITGMATAECMNMGI 402
I G+ A G+
Sbjct: 180 GAIAGVCEAITYAKGV 195
>UniRef50_Q8KL12 Cluster: Probable 6-phosphogluconate dehydrogenase
protein; n=1; Rhizobium etli CFN 42|Rep: Probable
6-phosphogluconate dehydrogenase protein - Rhizobium
etli (strain CFN 42 / ATCC 51251)
Length = 294
Score = 91.1 bits (216), Expect = 8e-18
Identities = 52/137 (37%), Positives = 74/137 (54%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
V V++L + K+V D L KDG +L+ID S+ PN +++ +KGL DA
Sbjct: 65 VAVTMLPNGKIVQDA-LFKDGAWQSLSADALVIDMSSSAPNDTRELAERLHQKGLRLVDA 123
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSGGV A +L MAGG +D +++ P+L MG + F G IGSG K NN + G
Sbjct: 124 PVSGGVKRAVEGSLTIMAGGASDDIDQADPILCAMGGQIFRTGPIGSGHAMKAINNFVSG 183
Query: 361 ITGMATAECMNMGIKMG 411
+A E + +G G
Sbjct: 184 AGVLAAIEGVLLGRTFG 200
>UniRef50_Q18X68 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Desulfitobacterium hafniense|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Desulfitobacterium hafniense (strain DCB-2)
Length = 298
Score = 91.1 bits (216), Expect = 8e-18
Identities = 50/137 (36%), Positives = 76/137 (55%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
++ L +++VV V LG+ G+ + G +++D+STI+ + +I G+ F DA
Sbjct: 58 IIFCSLPNSEVVCQVVLGETGLKKVLRAGQIIVDTSTINYSTTLEIGKQLESVGVEFIDA 117
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSG A+ TL M GG++E FE P L+ K + GQ GSGQ+ KL N +L
Sbjct: 118 PVSGMESRAKEGTLTTMCGGKQELFENVKPYLQCFADKILYMGQPGSGQLTKLINQLLFD 177
Query: 361 ITGMATAECMNMGIKMG 411
I A AE + M +K+G
Sbjct: 178 INVAALAEILPMSVKLG 194
>UniRef50_A1B741 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3;
Bacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Paracoccus denitrificans (strain Pd 1222)
Length = 309
Score = 91.1 bits (216), Expect = 8e-18
Identities = 51/137 (37%), Positives = 74/137 (54%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
+V + L + V + G G+V G++ +D ST +V +QI KG+ F DA
Sbjct: 59 IVFTSLPTPADVRNAGFGPRGLVEGMAPGTVWLDLSTNSVDVVRQIHAELAPKGIHFIDA 118
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSGG GA + LA GG +E ++R LP L+ M + + G IG+G +AKL NNM
Sbjct: 119 PVSGGPAGAASGQLAIWCGGEREVYDRCLPWLEKMADQPRYIGDIGAGTIAKLVNNMAST 178
Query: 361 ITGMATAECMNMGIKMG 411
AE ++MG+K G
Sbjct: 179 AIISVLAEALSMGVKAG 195
>UniRef50_A5VBF0 Cluster: 2-hydroxy-3-oxopropionate reductase
precursor; n=1; Sphingomonas wittichii RW1|Rep:
2-hydroxy-3-oxopropionate reductase precursor -
Sphingomonas wittichii RW1
Length = 298
Score = 89.8 bits (213), Expect = 2e-17
Identities = 51/138 (36%), Positives = 73/138 (52%), Gaps = 1/138 (0%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKG-LGFTD 177
VV LT V V G+ G G+L++D STI P+ + E G + D
Sbjct: 61 VVCLCLTDADAVEQVMFGEGGAARALAPGALVVDFSTIGPDATRGFAKRLAETGDAQWLD 120
Query: 178 APVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLM 357
PVSGGV GA+ TLA +AGG +R PLL ++ A+ G +G+GQ AKL N +++
Sbjct: 121 CPVSGGVAGAEAGTLAILAGGDAAAIDRVRPLLALLSARVTRMGGVGAGQAAKLCNQLIV 180
Query: 358 GITGMATAECMNMGIKMG 411
+A AE M++G +G
Sbjct: 181 ATNMLAIAEAMHVGEALG 198
>UniRef50_Q0UVR9 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 288
Score = 89.8 bits (213), Expect = 2e-17
Identities = 58/143 (40%), Positives = 85/143 (59%), Gaps = 6/143 (4%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLG-KDGVVAHAK-KGSLLIDSSTIDPNVPKQIFPIALEKGLG-F 171
V++SI+ K V VYL K GV+A K +G L+++ STID K++ E+GLG +
Sbjct: 24 VLISIVPGGKDVKTVYLDEKTGVIAARKDEGRLMLECSTIDVESTKEVGRKLKEEGLGTY 83
Query: 172 TDAPVSGGVMGAQNATLAFMAGGRKEDFERSLP-LLKVMG--AKQFHCGQIGSGQVAKLT 342
DAPVSGGV A+ TL+ + G D LP L ++G +K F+ +G+G AK++
Sbjct: 84 IDAPVSGGVPAAEAGTLSMLIGAPPPDPTSLLPSTLSLLGTPSKFFYLHTLGAGLTAKIS 143
Query: 343 NNMLMGITGMATAECMNMGIKMG 411
NN L G +ATAE + +G+K G
Sbjct: 144 NNYLSGTILLATAEALAIGVKHG 166
>UniRef50_Q0LNZ7 Cluster: 3-hydroxyisobutyrate dehydrogenase
precursor; n=1; Herpetosiphon aurantiacus ATCC
23779|Rep: 3-hydroxyisobutyrate dehydrogenase precursor
- Herpetosiphon aurantiacus ATCC 23779
Length = 301
Score = 89.4 bits (212), Expect = 3e-17
Identities = 49/137 (35%), Positives = 68/137 (49%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
+V++++ V LG +G GS+ ID STI P + I E+ + DA
Sbjct: 63 IVITMVPDAPQVEAALLGTNGAAYGMAAGSICIDMSTIAPTASRAIAAKLAERQIAMLDA 122
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSGG A+ LA M GG FER +L+V+G + G GSG V KL NN+ +
Sbjct: 123 PVSGGPARAKTGELAIMVGGEPSTFERCQAVLEVLGGAVSYIGASGSGSVVKLCNNLAIS 182
Query: 361 ITGMATAECMNMGIKMG 411
I MA E + G+ G
Sbjct: 183 IIAMANIEALAFGVANG 199
>UniRef50_Q39FA8 Cluster: 2-hydroxy-3-oxopropionate reductase; n=22;
Burkholderiales|Rep: 2-hydroxy-3-oxopropionate reductase
- Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 287
Score = 89.0 bits (211), Expect = 3e-17
Identities = 53/140 (37%), Positives = 75/140 (53%), Gaps = 3/140 (2%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVV---AHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGF 171
V V +L + V DV G+ G++ A A++ ++D S+I P + A G+G+
Sbjct: 50 VFVCVL-DGRAVGDVVFGEHGLLSGDAAARRLQRIVDHSSIPPAATRDYAARATALGVGW 108
Query: 172 TDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNM 351
DAPVSGGV GAQ TLA MAGGR D + PL+ ++ H G G+GQ AKL N
Sbjct: 109 VDAPVSGGVPGAQAGTLAVMAGGRAADLDAVRPLIDTYASRITHMGDAGAGQTAKLCNQA 168
Query: 352 LMGITGMATAECMNMGIKMG 411
++ T A AE + + G
Sbjct: 169 IVTATVTAIAEAVGLAQASG 188
>UniRef50_A3VLN6 Cluster: Oxidoreductase; n=1; Rhodobacterales
bacterium HTCC2654|Rep: Oxidoreductase - Rhodobacterales
bacterium HTCC2654
Length = 293
Score = 89.0 bits (211), Expect = 3e-17
Identities = 47/136 (34%), Positives = 72/136 (52%), Gaps = 1/136 (0%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFP-IALEKGLGFTD 177
V+ +T K + V G DG+V + ++++D ST+ P+ +QI + E G + D
Sbjct: 59 VLCLCVTDAKALDAVLFGSDGIVGAGRVPAMIVDHSTVPPDATRQIAARVRAEAGAAWVD 118
Query: 178 APVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLM 357
APVSGG+ GA LA GG D R+ P+L +G H G GSGQVAK N ++
Sbjct: 119 APVSGGLAGAAAGQLAIFVGGEDADVTRAWPVLTTLGTTVTHLGPTGSGQVAKACNQVIG 178
Query: 358 GITGMATAECMNMGIK 405
++ A AE + + +
Sbjct: 179 FLSFAALAEALALAAR 194
>UniRef50_A6SW62 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Janthinobacterium sp. Marseille|Rep:
3-hydroxyisobutyrate dehydrogenase - Janthinobacterium
sp. (strain Marseille) (Minibacterium massiliensis)
Length = 298
Score = 88.6 bits (210), Expect = 4e-17
Identities = 52/136 (38%), Positives = 69/136 (50%)
Frame = +1
Query: 4 VVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 183
V+ +L S++VV V L DG+ GS+ ID T P V + I G+G+ DAP
Sbjct: 65 VIFMLPSDQVVRQV-LFTDGLATQLAPGSIAIDMGTSAPAVTRSISAELATLGIGYLDAP 123
Query: 184 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGI 363
V GGV+ A++A+L M G ER PL MG K + CG IGS V K N +
Sbjct: 124 VMGGVVFAKDASLDIMVSGDDASIERCRPLFDAMGRKLWPCGDIGSAHVLKAMTNYINAC 183
Query: 364 TGMATAECMNMGIKMG 411
+ T E M +G K G
Sbjct: 184 ALINTLEAMTIGRKFG 199
>UniRef50_A5GPC0 Cluster: Hydroxyacid dehydrogenase/reductase family
protein; n=14; Cyanobacteria|Rep: Hydroxyacid
dehydrogenase/reductase family protein - Synechococcus
sp. (strain WH7803)
Length = 302
Score = 88.6 bits (210), Expect = 4e-17
Identities = 45/132 (34%), Positives = 74/132 (56%)
Frame = +1
Query: 4 VVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 183
+V ++ + V V G +G +GSL+ID STI P+ +++ +G+ + DAP
Sbjct: 75 LVLCVSDDAAVEAVLWGDNGAGPALAEGSLVIDCSTISPSTSQRMARRLAHRGVRYLDAP 134
Query: 184 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGI 363
V+GG GA+ TL + GG D +R++P+L+ +G H G +GSGQ K N +L+
Sbjct: 135 VTGGTEGAKAGTLTVLCGGSDADLDRAMPVLETIGGSIHHFGAVGSGQQVKAVNQVLVAG 194
Query: 364 TGMATAECMNMG 399
+ A AE + +G
Sbjct: 195 SYAAVAEAIALG 206
>UniRef50_A3SJ77 Cluster: Probable oxidoreductase; n=1; Roseovarius
nubinhibens ISM|Rep: Probable oxidoreductase -
Roseovarius nubinhibens ISM
Length = 320
Score = 88.6 bits (210), Expect = 4e-17
Identities = 50/137 (36%), Positives = 69/137 (50%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
++++IL + V + LG G+ A G+L+I+ STI P I KGL DA
Sbjct: 70 IIMTILPRDTHVRQICLGAGGIADSAAPGTLVIEMSTISPEASLDIHDALTSKGLRVLDA 129
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PV AQN L MAGGR EDF + P+ + K H G GSG K+ NN +
Sbjct: 130 PVGRTPKDAQNGALLIMAGGRAEDFADAAPVFAPLADKIVHLGPKGSGIRMKIANNYMSM 189
Query: 361 ITGMATAECMNMGIKMG 411
++ + TAE + M K G
Sbjct: 190 VSMVLTAETLAMARKAG 206
>UniRef50_Q4Q7T9 Cluster: 2-hydroxy-3-oxopropionate reductase,
putative; n=6; Trypanosomatidae|Rep:
2-hydroxy-3-oxopropionate reductase, putative -
Leishmania major
Length = 299
Score = 88.6 bits (210), Expect = 4e-17
Identities = 51/138 (36%), Positives = 77/138 (55%), Gaps = 1/138 (0%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFP-IALEKGLGFTD 177
VV + L+ + V++V G +GV A +G++ +D+STI P+V ++I + EK + D
Sbjct: 59 VVFTNLSDSPDVMEVVFGPNGVAAGICEGAIFVDNSTIKPSVAQEIARRLWKEKKVRALD 118
Query: 178 APVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLM 357
APVSGG +GA+N TL M GG LP+L +G K H G G+GQV K N +++
Sbjct: 119 APVSGGDIGARNGTLTVMVGGDAAALATVLPVLLAVGKKVTHIGDCGAGQVCKAANQIMV 178
Query: 358 GITGMATAECMNMGIKMG 411
+A E + K G
Sbjct: 179 AAQMVALGEILVFCEKCG 196
>UniRef50_A1UP64 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Mycobacterium|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Mycobacterium sp. (strain
KMS)
Length = 305
Score = 88.2 bits (209), Expect = 6e-17
Identities = 47/119 (39%), Positives = 65/119 (54%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
VV+++L + V +V G GV + GSL+ID STI P+ I EK + F DA
Sbjct: 59 VVITMLPDSPEVEEVLFGPAGVTTTLRPGSLVIDCSTISPDAAVAIGARLAEKDIAFVDA 118
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLM 357
PVSGG GA LA M GG ++ R+ +L + A H G +G+GQ+ K N ML+
Sbjct: 119 PVSGGEAGAIAGALAVMMGGDEDAVRRAATVLDAVAATSVHVGPVGAGQLVKAANQMLV 177
>UniRef50_Q0S5S3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Rhodococcus sp. RHA1|Rep: 3-hydroxyisobutyrate
dehydrogenase - Rhodococcus sp. (strain RHA1)
Length = 299
Score = 87.8 bits (208), Expect = 8e-17
Identities = 43/116 (37%), Positives = 64/116 (55%)
Frame = +1
Query: 64 VVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGR 243
V+ +G +++D STIDP+ +++ A G F DAPVSGGV GA+ TLA M GG
Sbjct: 79 VLQQGNQGLVIVDHSTIDPDTTRRLAQDAQVAGACFLDAPVSGGVQGAEAGTLAVMLGGD 138
Query: 244 KEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMG 411
+ ++ +PL++ FH G GSGQ KL NN + +A E ++ + G
Sbjct: 139 EASVKKVIPLIETYAGNIFHVGPSGSGQAIKLANNQITAANIVALGEGLSSAVAAG 194
>UniRef50_A5USN9 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Roseiflexus|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Roseiflexus sp. RS-1
Length = 302
Score = 87.8 bits (208), Expect = 8e-17
Identities = 50/137 (36%), Positives = 72/137 (52%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
+V +ILT + V VY G+DG+++ G L I+ STI + + + ++G DA
Sbjct: 60 LVFTILTDDHAVETVYCGRDGLLSTDASGRLFIEMSTIRTSTILSLAGMVDQRGARLLDA 119
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSG V A+ L + GGR D ER+ P L V+G + H G G+G KL NM M
Sbjct: 120 PVSGTVAPAREGQLLVLVGGRTSDLERARPALGVLGRRIIHLGGQGAGTTMKLVLNMTMA 179
Query: 361 ITGMATAECMNMGIKMG 411
A AE + +G + G
Sbjct: 180 CFWGALAESLAVGQQFG 196
>UniRef50_Q7WCG3 Cluster: Putative uncharacterized protein; n=2;
Bordetella|Rep: Putative uncharacterized protein -
Bordetella parapertussis
Length = 296
Score = 87.4 bits (207), Expect = 1e-16
Identities = 47/138 (34%), Positives = 71/138 (51%), Gaps = 2/138 (1%)
Frame = +1
Query: 4 VVSILTSNKVVLDVYLGKDGVVAHAKKGS--LLIDSSTIDPNVPKQIFPIALEKGLGFTD 177
VV +L ++ +++ LG G+ G ++ ST P+ + + G D
Sbjct: 63 VVVLLANDAQIMETMLGGQGLAQAVPAGHRPIVCMMSTTLPDTLRALEAPLAAVGARLVD 122
Query: 178 APVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLM 357
APVSGG++GA+ TL M GG D E PL++ MG + FHCG +GS ++AK+ NNML
Sbjct: 123 APVSGGIVGAEAGTLTIMMGGETADVEAVRPLMQAMGERLFHCGALGSAEIAKVINNMLC 182
Query: 358 GITGMATAECMNMGIKMG 411
TAE + + G
Sbjct: 183 VANMFLTAEAIELAESHG 200
>UniRef50_Q6C351 Cluster: Yarrowia lipolytica chromosome F of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome F of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 334
Score = 87.4 bits (207), Expect = 1e-16
Identities = 46/116 (39%), Positives = 66/116 (56%), Gaps = 5/116 (4%)
Frame = +1
Query: 79 KKGSLLIDSSTIDPNVPKQIFPIALEK--GLGFTDAPVSGGVMGAQNATLAFMAGGRKED 252
K + +D STID + + +K F DAPVSGGV+GA+ TL FM G K+
Sbjct: 117 KTSKIFVDCSTIDTQTSIECGKLVTDKDASAAFVDAPVSGGVVGAEKGTLTFMVGCNKDK 176
Query: 253 ---FERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMG 411
+++ LLK+MG + +CG G G AKL NN L+ +T +ATAE ++ K+G
Sbjct: 177 QQVYKQVEELLKLMGGRIVNCGTQGQGLAAKLANNYLLAVTNVATAEAFHLAEKLG 232
>UniRef50_Q4PCH4 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 366
Score = 87.4 bits (207), Expect = 1e-16
Identities = 53/142 (37%), Positives = 77/142 (54%), Gaps = 6/142 (4%)
Frame = +1
Query: 4 VVSILTSNKVVLD-VYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQ----IFPIALEKGLG 168
V S+ T +LD + + V A+ +L ID +T+DP+V Q I
Sbjct: 108 VESVYTHENGILDGLESFQAAAVDDAQAKTLCIDCTTLDPDVAVQTATAIKNANANGAFD 167
Query: 169 FTDAPVSGGVMGAQNATLAFMAGGRKED-FERSLPLLKVMGAKQFHCGQIGSGQVAKLTN 345
DAPVSGGV+GA ATL+FM G F + P L +MG++ HCG+ G+G +AK+ N
Sbjct: 168 MIDAPVSGGVVGANAATLSFMVGSDSSTTFASAEPYLSLMGSRAVHCGKNGNGLIAKIAN 227
Query: 346 NMLMGITGMATAECMNMGIKMG 411
N+L+GI+ + E M +G G
Sbjct: 228 NLLLGISMLGVTEAMLLGTAHG 249
>UniRef50_Q8EW87 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Mycoplasma penetrans|Rep: 3-hydroxyisobutyrate
dehydrogenase - Mycoplasma penetrans
Length = 288
Score = 87.0 bits (206), Expect = 1e-16
Identities = 48/132 (36%), Positives = 76/132 (57%), Gaps = 1/132 (0%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKD-GVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTD 177
++++++ VLD+YL + G+ + + ID +T PN Q+ + KG+ D
Sbjct: 59 IIMTMVGYPSDVLDIYLNDEYGIFNYVSSEQICIDFTTSSPNFAVQLANNS--KGIKVLD 116
Query: 178 APVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLM 357
APV+GG +GA N TL+ M GG E F++ +LK++G K + G G GQ AKL N +L+
Sbjct: 117 APVTGGDIGALNGTLSIMVGGDFETFKKVESILKILGNKINYFGSAGKGQHAKLFNQILV 176
Query: 358 GITGMATAECMN 393
+ ATAE +N
Sbjct: 177 AVNTFATAEVLN 188
>UniRef50_Q2BFK1 Cluster: Oxidoreductase; n=1; Bacillus sp. NRRL
B-14911|Rep: Oxidoreductase - Bacillus sp. NRRL B-14911
Length = 270
Score = 87.0 bits (206), Expect = 1e-16
Identities = 48/136 (35%), Positives = 74/136 (54%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
V++SIL ++K + V L ++ V+ G LI+ ++ P + K++ +KG+ D
Sbjct: 46 VIISILPADKEMESVLLSEE-VLNVLNPGQFLIEMTSGSPEMMKKVHAAYQQKGIPVLDG 104
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSGG GA+N TL MAGG + ER P+L+ M + G +G G+ K N ML G
Sbjct: 105 PVSGGTAGAENGTLTVMAGGDADVLERLRPVLESMATNIYLVGSVGDGKAIKAINQMLAG 164
Query: 361 ITGMATAECMNMGIKM 408
I A AE + + K+
Sbjct: 165 IHMAAAAEAVALAEKL 180
>UniRef50_Q0URA2 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 325
Score = 87.0 bits (206), Expect = 1e-16
Identities = 60/150 (40%), Positives = 80/150 (53%), Gaps = 14/150 (9%)
Frame = +1
Query: 4 VVSILTSNKVVLDVYLGKD-GVVAHAKKGS------LLIDSSTIDPN----VPKQIFPIA 150
V+++L + V VYL G++A A+ S L+++ TI+ + V K
Sbjct: 73 VITMLPDSNAVKKVYLDPSTGILAGAEANSGTKSDKLIMECGTIETSTILEVAKATSSSK 132
Query: 151 LEKGLGFTDAPVSGGVMGAQNATLAFMAGGR-KEDFERSLPLLKVMGAKQ--FHCGQIGS 321
+ L F DAPVSGG MGAQ+ TLAFMAG K F R L MG F CG IG+
Sbjct: 133 AAENLTFVDAPVSGGPMGAQDGTLAFMAGANNKAIFPRVKGYLSHMGKPDAIFLCGDIGA 192
Query: 322 GQVAKLTNNMLMGITGMATAECMNMGIKMG 411
G K+ NN L IT +A +E +N+G KMG
Sbjct: 193 GTAFKVINNYLSAITSLAASEALNIGTKMG 222
>UniRef50_A3H5R1 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Caldivirga maquilingensis IC-167|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Caldivirga maquilingensis IC-167
Length = 295
Score = 87.0 bits (206), Expect = 1e-16
Identities = 49/137 (35%), Positives = 75/137 (54%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
VV+SI++ + V + LG++GV+ K+GSL+I+ STI P+ ++ EKG DA
Sbjct: 61 VVLSIVSDDDAVKSIMLGENGVINGIKQGSLVIEMSTISPSTSIELANKIKEKGGLMVDA 120
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
P+ G + + + GG +E +ER+ ++K H G G G AKL NN L+G
Sbjct: 121 PIIGTSILIEKREAVVLIGGEREAYERAYEVVKHFARYVVHVGPNGYGLYAKLINNALLG 180
Query: 361 ITGMATAECMNMGIKMG 411
A AE +N+G MG
Sbjct: 181 SYVAALAEVVNLGEAMG 197
>UniRef50_A0N0V2 Cluster: BtdhL; n=1; Azoarcus anaerobius|Rep: BtdhL
- Azoarcus anaerobius
Length = 303
Score = 86.6 bits (205), Expect = 2e-16
Identities = 44/137 (32%), Positives = 73/137 (53%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
+V+S+++ + + + L GV A G + ID ST+ P + ++I A KG+ + A
Sbjct: 65 IVISMVSDDAALQGITLDAGGVFEAATPGMVFIDMSTVSPALSERIAAAASAKGIHYLRA 124
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSG A L +A G K+ +ER LPLL+ MG K ++ G + K+ NM++G
Sbjct: 125 PVSGSTTTAAAGALTILASGPKDAYERCLPLLQAMGKKLYYLGPAEQARYLKVAINMMLG 184
Query: 361 ITGMATAECMNMGIKMG 411
+T E + +G + G
Sbjct: 185 VTAGMLGEALALGERGG 201
>UniRef50_Q5L168 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=15;
Bacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Geobacillus kaustophilus
Length = 288
Score = 86.2 bits (204), Expect = 2e-16
Identities = 44/137 (32%), Positives = 75/137 (54%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
VV++++ + V VY G+ G++ +A+ G+ +ID +T P + + I+ A +KG+ DA
Sbjct: 60 VVMTMVGDPRDVEQVYFGEGGILENARPGTYVIDMTTSTPTLAQSIYEAAKQKGIHALDA 119
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSGG +GA+ TL M GG ++ F P+L+ +G G G+GQ K+ N + +
Sbjct: 120 PVSGGDIGAREGTLTIMVGGDEDVFLACKPILERLGTNIVRQGGAGAGQHTKMCNQIAIA 179
Query: 361 ITGMATAECMNMGIKMG 411
+ E M + G
Sbjct: 180 TNMIGVCEAMAYAKRAG 196
>UniRef50_Q0RCX7 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Frankia alni ACN14a|Rep: 3-hydroxyisobutyrate
dehydrogenase - Frankia alni (strain ACN14a)
Length = 313
Score = 85.8 bits (203), Expect = 3e-16
Identities = 47/137 (34%), Positives = 69/137 (50%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
VV + ++ V V LG DG + G+ ++D +T + +I A E G+GF DA
Sbjct: 60 VVCVCVGADDDVRSVLLGPDGALGALAPGATIVDHTTTSAELAVEIAARAAEVGVGFVDA 119
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSGG GA+ L+ M GG + ER P+L GA G +G+GQ+ K+ N +L+
Sbjct: 120 PVSGGQAGAEAGRLSVMCGGEVDTVERVRPVLAAYGATITRIGPVGTGQLTKMVNQILVA 179
Query: 361 ITGMATAECMNMGIKMG 411
AE +N G
Sbjct: 180 GAIEGAAEALNFAAAAG 196
>UniRef50_Q606G9 Cluster: Oxidoreductase, Gfo/Idh/MocA family; n=6;
Proteobacteria|Rep: Oxidoreductase, Gfo/Idh/MocA family
- Methylococcus capsulatus
Length = 289
Score = 85.4 bits (202), Expect = 4e-16
Identities = 44/133 (33%), Positives = 72/133 (54%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
V+V+ ++++ VL+V + + G++++D ST+ ++ + + G F DA
Sbjct: 60 VIVTCVSADADVLEVIAA---LTPGLRPGAVIVDCSTVGVATARRAAEVVRQAGGDFLDA 116
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSGGV GA++ TLA M GGR E E+ P+L MG++ H G G+GQ K N ++
Sbjct: 117 PVSGGVEGARDGTLALMIGGRAETVEKVRPVLAAMGSRLMHMGDTGAGQATKAVNQVMCA 176
Query: 361 ITGMATAECMNMG 399
A E + G
Sbjct: 177 GINQAVTEALAFG 189
>UniRef50_A3WAC4 Cluster: Dehydrogenase; n=4; Bacteria|Rep:
Dehydrogenase - Erythrobacter sp. NAP1
Length = 301
Score = 85.4 bits (202), Expect = 4e-16
Identities = 42/117 (35%), Positives = 68/117 (58%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
VV++ L ++ V V G++GV+A K+G+ ID +++ P + ++I GL DA
Sbjct: 69 VVLACLGNDDDVASVLFGENGVLAAMKRGATFIDHTSVSPGLARRIADECERLGLHAVDA 128
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNM 351
PVSGG GA+N L+ M GG +E + P+++ A+ H G+ G+GQ AK N +
Sbjct: 129 PVSGGQAGAENGKLSIMCGGSEEAMASAQPVMQAYAARIVHIGEAGAGQTAKAINQV 185
>UniRef50_A0FZ96 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Burkholderia phymatum STM815|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Burkholderia phymatum STM815
Length = 305
Score = 85.0 bits (201), Expect = 5e-16
Identities = 48/138 (34%), Positives = 73/138 (52%), Gaps = 1/138 (0%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
VV+ L + V V G DG V G ++ID ++ P + + G+ DA
Sbjct: 58 VVLLCLPRSSDVHSVLFGPDGAVEGLSDGKIVIDQTSGVPAETRDFARQLADIGVALFDA 117
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQ-IGSGQVAKLTNNMLM 357
PVSG + A T++ +A G K+ FE++LP+L+ + FHCG+ +G+GQ K NNM+
Sbjct: 118 PVSGAMATAIAGTISIIASGPKDAFEKTLPVLQSISPNVFHCGERVGNGQTMKTVNNMMN 177
Query: 358 GITGMATAECMNMGIKMG 411
+AT E + MG K G
Sbjct: 178 VSCRLATLEVVAMGRKFG 195
>UniRef50_A3X9R7 Cluster: 3-hydroxyisobutyrate dehydrogenase family
protein; n=2; Rhodobacterales|Rep: 3-hydroxyisobutyrate
dehydrogenase family protein - Roseobacter sp. MED193
Length = 300
Score = 84.6 bits (200), Expect = 7e-16
Identities = 40/113 (35%), Positives = 62/113 (54%)
Frame = +1
Query: 73 HAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKED 252
+ KKGS+++D+ST +P+ K++ A G F D PVSGG +GA+ T+ + GG +
Sbjct: 93 YLKKGSIVVDTSTSEPDTTKRLAAAAESNGYTFLDGPVSGGPLGARTGTMTMVVGGDEAG 152
Query: 253 FERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMG 411
F + PLL+ M K H G G+G K+ NN+L + +E M + G
Sbjct: 153 FTKVRPLLEKMTGKLVHIGPSGAGHTVKIANNLLCAANLVLMSEMAQMAERAG 205
>UniRef50_Q0F1Y7 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding protein; n=1; Mariprofundus ferrooxydans
PV-1|Rep: 6-phosphogluconate dehydrogenase, NAD-binding
protein - Mariprofundus ferrooxydans PV-1
Length = 289
Score = 84.2 bits (199), Expect = 9e-16
Identities = 46/137 (33%), Positives = 71/137 (51%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
V++ +LT + V V G++G+++ +G +I+ ST+ K+ + G+ DA
Sbjct: 61 VIILMLTGEEAVDAVLFGEEGLLSGDCEGKTVINMSTVPVECSKRWAKELADHGMTLIDA 120
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSG + AQ TL +AGG + PLL MG K +CG GSG KL N+L+G
Sbjct: 121 PVSGSKVPAQTGTLVILAGGPEAAVRAQEPLLLSMGKKVIYCGPTGSGSAMKLAINLLLG 180
Query: 361 ITGMATAECMNMGIKMG 411
I AE +++ G
Sbjct: 181 IMTEGIAEALHLAESSG 197
>UniRef50_Q01QM2 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Solibacter usitatus Ellin6076|Rep: 3-hydroxyisobutyrate
dehydrogenase - Solibacter usitatus (strain Ellin6076)
Length = 298
Score = 83.8 bits (198), Expect = 1e-15
Identities = 48/137 (35%), Positives = 71/137 (51%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
VV + + +V LG G++ + G++++D STI ++I K + F DA
Sbjct: 61 VVFLCVGDTAMAREVILGGQGLIQGLRAGAVVVDCSTIAVADSREIGAALKAKSVDFLDA 120
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PV+G GA++ L FM GG + F + PLL MG K + CG G G AKLT N+++
Sbjct: 121 PVTGSTPGAESGNLTFMIGGDEAVFSKIRPLLDPMGKKIYFCGGAGMGLQAKLTQNLVLS 180
Query: 361 ITGMATAECMNMGIKMG 411
MA E M + K G
Sbjct: 181 NILMAFNEGMVLATKGG 197
>UniRef50_Q3DYV4 Cluster: NADP oxidoreductase, coenzyme
F420-dependent:6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Chloroflexus|Rep: NADP oxidoreductase,
coenzyme F420-dependent:6-phosphogluconate
dehydrogenase, NAD-binding - Chloroflexus aurantiacus
J-10-fl
Length = 289
Score = 83.4 bits (197), Expect = 2e-15
Identities = 41/104 (39%), Positives = 60/104 (57%)
Frame = +1
Query: 79 KKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFE 258
++G L+ID + DP + +G+G+ DAPVSGG GA TLA M GG D E
Sbjct: 79 REGQLIIDMGSSDPRHSQTHATTLANRGIGWVDAPVSGGPEGAAAGTLAIMVGGTASDVE 138
Query: 259 RSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECM 390
R+ P+L+ +G + H G G+G K+ N +++G+T A AE M
Sbjct: 139 RAEPILRALG-RPTHVGPPGAGHTVKVINQLIVGLTIQAVAEAM 181
>UniRef50_A5VEA3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
Sphingomonas wittichii RW1|Rep:
2-hydroxy-3-oxopropionate reductase - Sphingomonas
wittichii RW1
Length = 264
Score = 83.4 bits (197), Expect = 2e-15
Identities = 44/137 (32%), Positives = 75/137 (54%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
VV+ + S++ V DV G+DGV+A A+ G +++ S++ + + ++G+ DA
Sbjct: 59 VVMICVVSDQQVRDVLAGEDGVLASARPGLIVVLHSSVSTDTIAEAAKATRDRGVVLVDA 118
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSGG GA+ T++FM GG + +R PL ++ G G G+ +AKL + + +
Sbjct: 119 PVSGGAQGARARTMSFMVGGEEAALDRCQPLFELSGPNILRTGPAGTATLAKLAHQVAII 178
Query: 361 ITGMATAECMNMGIKMG 411
MA AE + +G G
Sbjct: 179 GNIMAMAEAVRLGTAGG 195
>UniRef50_Q47AR2 Cluster: NADP oxidoreductase, coenzyme
F420-dependent:6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Dechloromonas aromatica RCB|Rep: NADP
oxidoreductase, coenzyme
F420-dependent:6-phosphogluconate dehydrogenase,
NAD-binding - Dechloromonas aromatica (strain RCB)
Length = 287
Score = 83.0 bits (196), Expect = 2e-15
Identities = 44/117 (37%), Positives = 62/117 (52%)
Frame = +1
Query: 61 GVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGG 240
GV + + G + +D STI P ++I G+ F DAPVSGG +GA +L+ MAGG
Sbjct: 76 GVASAGESGLVAVDMSTIAPAAARRIGEDLAAAGIDFIDAPVSGGEVGAIAGSLSIMAGG 135
Query: 241 RKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMG 411
F ++ P + MG H G G+GQVAK N ++ G+ +A AE K G
Sbjct: 136 SDAAFAKAKPAFECMGKNIVHVGASGAGQVAKAANQIVTGMGVLAVAEAFAFAAKNG 192
>UniRef50_Q13LQ9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=11;
Proteobacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Burkholderia xenovorans (strain LB400)
Length = 296
Score = 83.0 bits (196), Expect = 2e-15
Identities = 46/139 (33%), Positives = 71/139 (51%), Gaps = 3/139 (2%)
Frame = +1
Query: 4 VVSILTSNKVVLDVYLG---KDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFT 174
++++L ++ +V V LG G A KG+++ID S+ +P + + + L +
Sbjct: 63 LITMLPNSAIVEAVVLGDGNNTGWAARLAKGAVVIDMSSSEPERSRALGKTLEAQRLAYL 122
Query: 175 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNML 354
DAPVSGGV A+ TLA + GG + R PLL MG H G G+G AK NN +
Sbjct: 123 DAPVSGGVKRAKEGTLAILVGGHADVLARCKPLLDAMGTNVLHIGTAGAGHAAKALNNYV 182
Query: 355 MGITGMATAECMNMGIKMG 411
+ AT E + + + G
Sbjct: 183 SAASVAATVEALQIASRFG 201
>UniRef50_A6SUL3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
Janthinobacterium sp. Marseille|Rep:
2-hydroxy-3-oxopropionate reductase - Janthinobacterium
sp. (strain Marseille) (Minibacterium massiliensis)
Length = 304
Score = 83.0 bits (196), Expect = 2e-15
Identities = 47/130 (36%), Positives = 74/130 (56%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
+V+++L + +V V D + K G+L+ID S+ + +++ +G+ F DA
Sbjct: 66 IVITMLEAGPIVAQVI---DAALPGLKHGALVIDMSSTRQSEAQEVHAKLAAQGVRFIDA 122
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSGGV+GA+ +LA MAGG +DF + +L VMG G G GQ+AKL N +++G
Sbjct: 123 PVSGGVVGAEAGSLAIMAGGSAQDFAEAEAVLTVMGRPTL-VGPAGCGQIAKLCNQLIVG 181
Query: 361 ITGMATAECM 390
T AE +
Sbjct: 182 GTLNIVAEAL 191
>UniRef50_Q1GJB9 Cluster: 6-phosphogluconate dehydrogenase
NAD-binding; n=1; Silicibacter sp. TM1040|Rep:
6-phosphogluconate dehydrogenase NAD-binding -
Silicibacter sp. (strain TM1040)
Length = 304
Score = 82.2 bits (194), Expect = 4e-15
Identities = 48/138 (34%), Positives = 72/138 (52%), Gaps = 1/138 (0%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKD-GVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTD 177
+V+S+ T+ V+ V + G +A +++D+ST + + + G GF D
Sbjct: 66 IVLSLPTAQHVLAVVQAAQAAGHLAQTGAARVIVDTSTSEAATSRTLAAELSALGHGFLD 125
Query: 178 APVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLM 357
APVSGG GA + L+ M GG + E + P L+ M AK H G G+G VAKL NNML+
Sbjct: 126 APVSGGPAGAASGQLSVMLGGETQWLEAARPALEAMAAKILHVGPSGAGNVAKLVNNMLV 185
Query: 358 GITGMATAECMNMGIKMG 411
+ T E + +G G
Sbjct: 186 ANHMVTTLEALRLGEAAG 203
>UniRef50_Q89R44 Cluster: Oxidoreductase; n=23; Bacteria|Rep:
Oxidoreductase - Bradyrhizobium japonicum
Length = 305
Score = 81.8 bits (193), Expect = 5e-15
Identities = 45/138 (32%), Positives = 67/138 (48%), Gaps = 1/138 (0%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
VVVS++ + + GKDGV K S+ + S+T+DP+V +++ G + DA
Sbjct: 67 VVVSVVVNAAQTETILFGKDGVAETMPKDSVFLSSATMDPDVARRLAKQLEATGRHYLDA 126
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQ-IGSGQVAKLTNNMLM 357
P+SGG A L +A G F ++ P L M AK + G G G K+ N +L
Sbjct: 127 PISGGAQRAAQGELTILASGSPAAFAKARPALDAMAAKLYELGDAAGQGAAFKMINQLLA 186
Query: 358 GITGMATAECMNMGIKMG 411
G+ A +E M K G
Sbjct: 187 GVHIAAASEAMAFAAKQG 204
>UniRef50_Q6UCZ9 Cluster: Predicted oxidoreductase; n=2;
environmental samples|Rep: Predicted oxidoreductase -
uncultured marine proteobacterium ANT32C12
Length = 309
Score = 81.8 bits (193), Expect = 5e-15
Identities = 43/137 (31%), Positives = 74/137 (54%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
V+ + ++ V ++ GK G++ G+++ID +T + K++ +AL+K + F DA
Sbjct: 80 VIALCVGRDEDVREMMSGKKGILNSVNPGTIIIDHTTTSATLSKEMNELALQKDVIFLDA 139
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
P+SGG GA++ L+ M GG K +E P+L + G GSGQ+ K+ N + +
Sbjct: 140 PISGGQAGAESGQLSVMVGGDKASYESVKPILDNYSKFTKYMGPSGSGQLTKMVNQICIA 199
Query: 361 ITGMATAECMNMGIKMG 411
A AE +N K+G
Sbjct: 200 GLVQALAEGVNFSEKVG 216
>UniRef50_A1R2J4 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Arthrobacter aurescens TC1|Rep: 3-hydroxyisobutyrate
dehydrogenase - Arthrobacter aurescens (strain TC1)
Length = 332
Score = 81.8 bits (193), Expect = 5e-15
Identities = 49/139 (35%), Positives = 70/139 (50%), Gaps = 2/139 (1%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
VV+++L + K V V +G G++A G +D ST P V ++ +G+ DA
Sbjct: 82 VVITMLPTPKHVETVAMGPGGILAGMPDGGTWVDMSTSVPEVANRVREAGSVRGIRVLDA 141
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQ--FHCGQIGSGQVAKLTNNML 354
PVSG +GA N L GG D ER P+ + MG + H G G+G KL N L
Sbjct: 142 PVSGMSVGAANGMLQIFVGGEPADVERLRPVFEAMGDPERILHVGGHGAGYAVKLMINQL 201
Query: 355 MGITGMATAECMNMGIKMG 411
+ATAE ++ G+K G
Sbjct: 202 WFSHLVATAEVLSTGVKAG 220
>UniRef50_Q89UN2 Cluster: Bll1384 protein; n=9; Bacteria|Rep:
Bll1384 protein - Bradyrhizobium japonicum
Length = 356
Score = 81.4 bits (192), Expect = 7e-15
Identities = 49/136 (36%), Positives = 72/136 (52%)
Frame = +1
Query: 4 VVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 183
V++ L S + L+V G +GV+ + ID ST+ + +I + ++ + D P
Sbjct: 114 VMASLPSLQASLEVATGTNGVI-EGSRVKRFIDLSTVGSTMASKIHGLLAKRDIVQIDCP 172
Query: 184 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGI 363
VSGGV GA+ TLA M G K +FE P L V+G F + G+ Q KL NN L
Sbjct: 173 VSGGVGGAEKGTLAVMVSGPKAEFELLKPALDVIGKVFFIGEKPGAAQTMKLANNFLSAT 232
Query: 364 TGMATAECMNMGIKMG 411
+AT+E + MG+K G
Sbjct: 233 AIVATSEAVVMGVKAG 248
>UniRef50_Q1YHQ4 Cluster: Putative 2-hydroxy-3-oxopropionate
reductase; n=1; Aurantimonas sp. SI85-9A1|Rep: Putative
2-hydroxy-3-oxopropionate reductase - Aurantimonas sp.
SI85-9A1
Length = 292
Score = 81.4 bits (192), Expect = 7e-15
Identities = 49/138 (35%), Positives = 70/138 (50%), Gaps = 1/138 (0%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAK-KGSLLIDSSTIDPNVPKQIFPIALEKGLGFTD 177
++ LT++ V V G DG+VA K G ++D ST + V Q+ G F D
Sbjct: 60 IIALCLTTSDAVASVVTGADGLVASRKLSGRTVVDFSTTEMAVTHQVAAAIEAVGGRFVD 119
Query: 178 APVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLM 357
APVSGG A+ TLA M GG ++ E + P+L+ +G + H G IG+GQ KL N +L
Sbjct: 120 APVSGGPGAAETGTLAIMFGGSEQAAEAARPMLEQLG-RATHMGAIGTGQATKLVNQVLC 178
Query: 358 GITGMATAECMNMGIKMG 411
AE + + G
Sbjct: 179 LTNYCVAAEALRLAQAYG 196
>UniRef50_Q0FFH2 Cluster: Putative 2-hydroxyacid dehydrogenase; n=2;
Alphaproteobacteria|Rep: Putative 2-hydroxyacid
dehydrogenase - alpha proteobacterium HTCC2255
Length = 303
Score = 81.0 bits (191), Expect = 9e-15
Identities = 42/137 (30%), Positives = 73/137 (53%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
+V +++ K + + G++G++ G + +D +T P + +++ ++ G DA
Sbjct: 59 IVFTMVFGPKQIEQIIRGENGLLHSMGPGQVWVDLTTNQPELARELAQEIIDTGAIAIDA 118
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PV+G V GA+N + AGG KE ER P++++MG + G GSG + KL +N L
Sbjct: 119 PVTGAVDGARNGNMTQFAGGDKETIERIRPVMELMGPVHY-MGSNGSGSITKLASNQLWA 177
Query: 361 ITGMATAECMNMGIKMG 411
I A E + M +K G
Sbjct: 178 IHATAMGEALVMAVKSG 194
>UniRef50_A4SWE8 Cluster: 2-hydroxy-3-oxopropionate reductase
precursor; n=7; Proteobacteria|Rep:
2-hydroxy-3-oxopropionate reductase precursor -
Polynucleobacter sp. QLW-P1DMWA-1
Length = 299
Score = 81.0 bits (191), Expect = 9e-15
Identities = 43/137 (31%), Positives = 68/137 (49%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
++ +++ V V G+ GV KG +++D S+I P K G + DA
Sbjct: 61 IIFTMVPDTPDVEKVLFGEHGVAHGLSKGKIVVDMSSISPIATKDFAKKINALGCEYLDA 120
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSGG +GA+ TL M GG++ F+ P+ +MG G G+GQV K+ N +++
Sbjct: 121 PVSGGQVGAKGGTLTIMVGGKESVFQTVKPMFDLMGKNITLVGDNGAGQVTKVANQIIVA 180
Query: 361 ITGMATAECMNMGIKMG 411
+ A AE + K G
Sbjct: 181 LNIEAVAEALLFASKAG 197
>UniRef50_Q84VC8 Cluster: Gamma hydroxybutyrate dehydrogenase-like
protein; n=3; Magnoliophyta|Rep: Gamma hydroxybutyrate
dehydrogenase-like protein - Oryza sativa subsp.
japonica (Rice)
Length = 293
Score = 81.0 bits (191), Expect = 9e-15
Identities = 44/135 (32%), Positives = 69/135 (51%)
Frame = +1
Query: 7 VSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 186
+++L+ L V KDGV+ +G +D ST+D +I +KG F +APV
Sbjct: 61 IAMLSDPSAALSVVFDKDGVLEQIGEGKGYVDMSTVDAATSCKISEAIKQKGGAFVEAPV 120
Query: 187 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 366
SG A++ L +A G K ++ +P V+G K F G+IG+G KL NM+MG
Sbjct: 121 SGSKKPAEDGQLVILAAGDKVLYDDMVPAFDVLGKKSFFLGEIGNGAKMKLVVNMIMGSM 180
Query: 367 GMATAECMNMGIKMG 411
A +E +++ G
Sbjct: 181 MNALSEGLSLADNSG 195
>UniRef50_Q94B07 Cluster: Gamma hydroxybutyrate dehydrogenase; n=16;
cellular organisms|Rep: Gamma hydroxybutyrate
dehydrogenase - Arabidopsis thaliana (Mouse-ear cress)
Length = 289
Score = 80.2 bits (189), Expect = 2e-14
Identities = 46/135 (34%), Positives = 68/135 (50%)
Frame = +1
Query: 7 VSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 186
+++L+ L V K GV+ +G ID ST+D +I KG F + PV
Sbjct: 61 IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV 120
Query: 187 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 366
SG A++ L +A G K FE S+P V+G + F+ GQ+G+G KL NM+MG
Sbjct: 121 SGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSM 180
Query: 367 GMATAECMNMGIKMG 411
A +E + + K G
Sbjct: 181 MNAFSEGLVLADKSG 195
>UniRef50_A7PEG7 Cluster: Chromosome chr11 scaffold_13, whole genome
shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome
chr11 scaffold_13, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 348
Score = 80.2 bits (189), Expect = 2e-14
Identities = 52/138 (37%), Positives = 71/138 (51%), Gaps = 1/138 (0%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLG-KDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTD 177
VV SI+ V V L G ++ + G +L+D +T DP++ +I A +G D
Sbjct: 107 VVFSIVGFPSDVRSVLLDPSSGALSGLRPGGVLVDMTTSDPSLAAEIASSAASRGCFSVD 166
Query: 178 APVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLM 357
APVSGG GA+NATLA AGG + R PL +G K + G G GQ AKL N +++
Sbjct: 167 APVSGGDRGAKNATLAIFAGGDESVVRRLNPLFSHLG-KVNYMGGPGKGQYAKLANQIII 225
Query: 358 GITGMATAECMNMGIKMG 411
T + E M K G
Sbjct: 226 ASTMLGLIEGMMYAYKSG 243
>UniRef50_Q39MY1 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Burkholderia sp. 383|Rep: 3-hydroxyisobutyrate
dehydrogenase - Burkholderia sp. (strain 383)
(Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 /
R18194))
Length = 303
Score = 79.4 bits (187), Expect = 3e-14
Identities = 49/138 (35%), Positives = 74/138 (53%), Gaps = 1/138 (0%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
+V + L + V L V LG DGVV H L ++ STI ++ ++I ++G+ DA
Sbjct: 63 IVFACLPNRDVSLAVGLGPDGVV-HGSAVRLYVEMSTIGQDMIERIGEGLAQRGIDIVDA 121
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCG-QIGSGQVAKLTNNMLM 357
PVSGG A+ TLA + G E+ PLL+ +G + F G + G Q+ K+ NN++M
Sbjct: 122 PVSGGPSAARAGTLAMLVSGMPSAVEQVSPLLERIGKEVFPMGDRPGMAQIMKIVNNVVM 181
Query: 358 GITGMATAECMNMGIKMG 411
+ AE + MG K G
Sbjct: 182 AANLVVCAEGLAMGAKAG 199
>UniRef50_P77161 Cluster: 2-hydroxy-3-oxopropionate reductase; n=99;
Proteobacteria|Rep: 2-hydroxy-3-oxopropionate reductase
- Escherichia coli (strain K12)
Length = 292
Score = 79.4 bits (187), Expect = 3e-14
Identities = 43/137 (31%), Positives = 70/137 (51%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
++ ++ V +V G++G + KG ++D S+I P K+ E G + DA
Sbjct: 58 IIFIMVPDTPQVEEVLFGENGCTKASLKGKTIVDMSSISPIETKRFARQVNELGGDYLDA 117
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSGG +GA+ TL+ M GG + FER PL +++G G G GQ K+ N +++
Sbjct: 118 PVSGGEIGAREGTLSIMVGGDEAVFERVKPLFELLGKNITLVGGNGDGQTCKVANQIIVA 177
Query: 361 ITGMATAECMNMGIKMG 411
+ A +E + K G
Sbjct: 178 LNIEAVSEALLFASKAG 194
>UniRef50_Q73P00 Cluster: 3-hydroxyacid dehydrogenase family
protein; n=4; Bacteria|Rep: 3-hydroxyacid dehydrogenase
family protein - Treponema denticola
Length = 292
Score = 79.0 bits (186), Expect = 4e-14
Identities = 43/130 (33%), Positives = 69/130 (53%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
++ +I+ + V + Y G+ G++ AK G++ D +T P + K+I+ A +K DA
Sbjct: 64 IIFTIVGYPQDVEETYFGEKGLLKTAKPGTIFADMTTSSPILAKKIYDEAKKKECFSVDA 123
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSGG +GA+N TL+ MAGG + F+ P MG G G+GQ K+ N + +
Sbjct: 124 PVSGGDIGAKNGTLSIMAGGDESAFKELEPFFACMGKTWALQGGAGAGQHTKMANQIAVA 183
Query: 361 ITGMATAECM 390
T E +
Sbjct: 184 ANLFGTVEAV 193
>UniRef50_A3WMG5 Cluster: Probable 3-hydroxyisobutyrate
dehydrogenase; n=1; Idiomarina baltica OS145|Rep:
Probable 3-hydroxyisobutyrate dehydrogenase - Idiomarina
baltica OS145
Length = 284
Score = 79.0 bits (186), Expect = 4e-14
Identities = 46/138 (33%), Positives = 74/138 (53%), Gaps = 1/138 (0%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKD-GVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTD 177
+V++++ + V+L + G ++ I+SST+ + K++ A ++G +
Sbjct: 60 LVIAMVRDDDASAAVWLDEQTGAFKGMSDNAIAIESSTLSVDWVKELAQQAQQRGKQLIE 119
Query: 178 APVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLM 357
APVSG AQNA L ++ GG R+ P+L +MG K H G++GSG +AKL N LM
Sbjct: 120 APVSGSRPQAQNAELVYLVGGDAHLVNRAEPVLSLMGKKVNHTGEMGSGALAKLVTNTLM 179
Query: 358 GITGMATAECMNMGIKMG 411
GI AE + M + G
Sbjct: 180 GIQVTTIAELIGMLKRQG 197
>UniRef50_A3EW86 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Leptospirillum sp. Group II UBA|Rep:
3-hydroxyisobutyrate dehydrogenase - Leptospirillum sp.
Group II UBA
Length = 279
Score = 78.2 bits (184), Expect = 6e-14
Identities = 43/120 (35%), Positives = 63/120 (52%)
Frame = +1
Query: 52 GKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFM 231
G DG+ + GSL+I+ STI P ++ L KG G+ D PVSG ++ A+ L +
Sbjct: 64 GPDGIARGLRPGSLVINMSTIAPEEAQEEALSLLAKGAGYLDVPVSGSLVPAEKGELLLL 123
Query: 232 AGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMG 411
AGG ER+ P+L G K H G GSG AKL N+L+ + + + +G +G
Sbjct: 124 AGGDGAALERARPILLHFGKKILHFGPTGSGMKAKLVINLLLASHVESLVQTVLVGESLG 183
>UniRef50_A0R1N4 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Mycobacterium|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Mycobacterium smegmatis
(strain ATCC 700084 / mc(2)155)
Length = 272
Score = 78.2 bits (184), Expect = 6e-14
Identities = 43/126 (34%), Positives = 64/126 (50%)
Frame = +1
Query: 34 VLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQN 213
V +V G+ GV+A G ++ ST+ P+ +I EKG+ DAPVSGG A+
Sbjct: 70 VREVLDGETGVLAGLAPGGIIAIHSTVHPDTCTEIAEQVAEKGISLIDAPVSGGEPAAKA 129
Query: 214 ATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMN 393
TL MAGG ++ ++ P+ G +GSGQVAK+ NN+L A +
Sbjct: 130 GTLLVMAGGDEDIVDKVRPVFATYADPVVRLGGVGSGQVAKILNNLLFSANLGAAMSALE 189
Query: 394 MGIKMG 411
+G +G
Sbjct: 190 LGEALG 195
>UniRef50_Q9LNP0 Cluster: F1L3.35; n=8; Magnoliophyta|Rep: F1L3.35 -
Arabidopsis thaliana (Mouse-ear cress)
Length = 387
Score = 78.2 bits (184), Expect = 6e-14
Identities = 42/125 (33%), Positives = 66/125 (52%)
Frame = +1
Query: 37 LDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNA 216
+DV GK+G + G +D ST+D I + G F +APVSG A++
Sbjct: 166 IDVACGKNGAIFGISSGKGYVDVSTVDVASSILISKQIKDTGALFLEAPVSGSKKPAEDG 225
Query: 217 TLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNM 396
L F+ G K +E++ P L +MG +F+ G++G+G KL NM+MG + AE + +
Sbjct: 226 QLIFLTAGDKPLYEKAAPFLDIMGKSKFYLGEVGNGAAMKLVVNMIMGSMMASFAEGILL 285
Query: 397 GIKMG 411
K+G
Sbjct: 286 SQKVG 290
>UniRef50_Q13PY3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Burkholderiales|Rep: 3-hydroxyisobutyrate dehydrogenase
- Burkholderia xenovorans (strain LB400)
Length = 302
Score = 77.8 bits (183), Expect = 8e-14
Identities = 49/138 (35%), Positives = 69/138 (50%), Gaps = 1/138 (0%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
VV L VV +V G GV + +++D ST P+V I ++ + F A
Sbjct: 59 VVFLSLPLPSVVEEVATGPHGV-SQGSSVRIVVDLSTTGPSVSNVIARKLADRHIQFLGA 117
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQ-IGSGQVAKLTNNMLM 357
PVSGG + A+ TL MA G E FE P L+V+G F+ G G GQ K+ NN L
Sbjct: 118 PVSGGTVAAEKGTLTVMAAGPMEAFETVEPWLRVIGKNIFYLGSGAGLGQTMKIINNTLC 177
Query: 358 GITGMATAECMNMGIKMG 411
+ +A+ E + G+K G
Sbjct: 178 AVGMVASCEALVFGVKAG 195
>UniRef50_Q7VYY0 Cluster: Putative oxidoreductase; n=4;
Bordetella|Rep: Putative oxidoreductase - Bordetella
pertussis
Length = 305
Score = 77.4 bits (182), Expect = 1e-13
Identities = 44/138 (31%), Positives = 71/138 (51%), Gaps = 3/138 (2%)
Frame = +1
Query: 4 VVSILTSNKVVLDVYLGKDG---VVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFT 174
V+++L ++ + V LG DG ++ + G+ ++D + +P +++ +GL
Sbjct: 67 VITMLPNSAITNAVVLGGDGQPGLIDLLESGAAIVDMGSSNPADTRRLSEQLAARGLTLI 126
Query: 175 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNML 354
DAPVSG V A TLA MAG + D R P+L+ MGA H G +GS K NN +
Sbjct: 127 DAPVSGAVAKASTGTLAIMAGAAEADLRRVRPILERMGAAIIHTGAVGSAHAMKALNNYV 186
Query: 355 MGITGMATAECMNMGIKM 408
+A +E M + +M
Sbjct: 187 YAAGLLAVSEAMVIARRM 204
>UniRef50_Q1IQE6 Cluster: 2-hydroxy-3-oxopropionate reductase
precursor; n=1; Acidobacteria bacterium Ellin345|Rep:
2-hydroxy-3-oxopropionate reductase precursor -
Acidobacteria bacterium (strain Ellin345)
Length = 282
Score = 77.4 bits (182), Expect = 1e-13
Identities = 40/117 (34%), Positives = 62/117 (52%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
VV ++ V V G GV + G +++DSSTI P + KG + DA
Sbjct: 54 VVWMCVSDTNAVERVLFGDGGVEPVLRAGMVVVDSSTISPVETLKFAERVRAKGADYIDA 113
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNM 351
P++G +GA++A L FM G + E ++ PL MG K H G++G GQ +K++ N+
Sbjct: 114 PITGSKIGAESAQLIFMVGAKDETLKKLEPLFLQMGKKIVHMGEVGKGQASKISLNL 170
>UniRef50_A6EH53 Cluster: Putative uncharacterized protein; n=1;
Pedobacter sp. BAL39|Rep: Putative uncharacterized
protein - Pedobacter sp. BAL39
Length = 292
Score = 77.4 bits (182), Expect = 1e-13
Identities = 41/135 (30%), Positives = 67/135 (49%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
+V +++ + V ++ G DG+++ G ++++ ST+ P + ++ G+ + DA
Sbjct: 71 IVFLMVSDDHAVASLFEGADGLLSKELHGKVIVNMSTVSPAISIKMAAACSAVGIEYLDA 130
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSG V A + L M GG ++ F + PLL MG H G G G AKL N L+
Sbjct: 131 PVSGSVKQATDGQLVIMVGGEEQAFHAAEPLLSCMGKLVMHLGASGIGNKAKLAINTLLA 190
Query: 361 ITGMATAECMNMGIK 405
I AE + K
Sbjct: 191 IYTEGLAEIVTFSRK 205
>UniRef50_A0G5F9 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Burkholderia|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Burkholderia phymatum
STM815
Length = 307
Score = 77.4 bits (182), Expect = 1e-13
Identities = 51/138 (36%), Positives = 69/138 (50%), Gaps = 1/138 (0%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
+V + L + + V LG DG + +L+D ST+ V K++ L KG+ DA
Sbjct: 71 IVFTSLPTPAIFRQVALG-DGGLIEGSAIKVLVDLSTVGSRVEKEVAQGLLAKGVETVDA 129
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCG-QIGSGQVAKLTNNMLM 357
PVSGG GA+ TLA MA G E L V+G K F G + G GQ+ KL NNML
Sbjct: 130 PVSGGAAGAKKGTLAIMAAGSPVALEEVRGLFDVLG-KAFVVGDKAGQGQLLKLLNNMLS 188
Query: 358 GITGMATAECMNMGIKMG 411
T+E G++ G
Sbjct: 189 STAFAITSEAFVAGVRGG 206
>UniRef50_Q8UBW3 Cluster: Oxidoredutase; n=1; Agrobacterium
tumefaciens str. C58|Rep: Oxidoredutase - Agrobacterium
tumefaciens (strain C58 / ATCC 33970)
Length = 300
Score = 77.0 bits (181), Expect = 1e-13
Identities = 48/130 (36%), Positives = 72/130 (55%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
+V+++L+ V +V L + GV KG+++IDSS+I P + ++ G+ DA
Sbjct: 68 IVITMLSDGNAVGEV-LFEAGVAEALAKGAVVIDSSSIAPPIAREHSSRLQAMGIHHVDA 126
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSGGV GA TLA MAGG + + + MG + + G G+GQ+ KL N ++
Sbjct: 127 PVSGGVPGATAGTLAIMAGGDEALISGLVDVFAPMG-RLTYVGPSGAGQLCKLANQQIVA 185
Query: 361 ITGMATAECM 390
IT A AE M
Sbjct: 186 ITIGAVAEAM 195
>UniRef50_Q2CHC8 Cluster: Oxidoreductase; n=1; Oceanicola granulosus
HTCC2516|Rep: Oxidoreductase - Oceanicola granulosus
HTCC2516
Length = 288
Score = 77.0 bits (181), Expect = 1e-13
Identities = 43/137 (31%), Positives = 69/137 (50%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
+VV + + V DV G G+ A A +++D ST+ P + I A + DA
Sbjct: 59 IVVLCVLDGRAVEDVCFGAQGL-AGAGGAEIVVDCSTVPPEATRDI---AGRMDAAWIDA 114
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSGG A+ L + GG++ D ER+ ++ + A H G +G+GQ AK N ++G
Sbjct: 115 PVSGGPQLAETGELTMLLGGQERDIERARAVIDALAANATHLGPLGAGQAAKTLNQAIVG 174
Query: 361 ITGMATAECMNMGIKMG 411
+ + AE + + K G
Sbjct: 175 VNYVLMAELLALARKSG 191
>UniRef50_A0NRG5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding protein; n=1; Stappia aggregata IAM
12614|Rep: 6-phosphogluconate dehydrogenase, NAD-binding
protein - Stappia aggregata IAM 12614
Length = 291
Score = 77.0 bits (181), Expect = 1e-13
Identities = 42/137 (30%), Positives = 66/137 (48%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
+V+++L + VY G DG+ + +L++ T+ + +++ A EKG F DA
Sbjct: 60 IVITMLADDAAAETVYFGPDGLFEASSGAQVLVEMGTLSVPMAERLARAAQEKGRRFVDA 119
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSG A++A L MAG D L V+G K G+ G+G KL NML+
Sbjct: 120 PVSGATQAAKDAKLLIMAGATASDAPELAALFDVLGRKTIWLGKAGAGAAMKLGVNMLIH 179
Query: 361 ITGMATAECMNMGIKMG 411
AE +++ G
Sbjct: 180 GLNQTLAEALSLTTAAG 196
>UniRef50_Q0C8I2 Cluster: Predicted protein; n=3;
Pezizomycotina|Rep: Predicted protein - Aspergillus
terreus (strain NIH 2624)
Length = 320
Score = 77.0 bits (181), Expect = 1e-13
Identities = 52/143 (36%), Positives = 75/143 (52%), Gaps = 7/143 (4%)
Frame = +1
Query: 4 VVSILTSNKVVLDVYLGKD-GVVAHAKKGSLLIDSSTIDP--NVPKQIFPIALEKGLGFT 174
+++++ V VYL + GV + LLID STID ++ + F
Sbjct: 72 IITMVPEGSHVRAVYLDESTGVCSTPLDTRLLIDCSTIDTATSLAVKAHITTHHASASFY 131
Query: 175 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLL----KVMGAKQFHCGQIGSGQVAKLT 342
DAPVSGGV+GAQ +AF G K D +LPLL ++MG + CG G AKL
Sbjct: 132 DAPVSGGVLGAQKGAIAFFLGCAKTD--PNLPLLTDTLRLMGKEVIPCGGPSLGLSAKLC 189
Query: 343 NNMLMGITGMATAECMNMGIKMG 411
NN L G+ +A +E +N+G++ G
Sbjct: 190 NNYLSGLIAIANSEALNIGMRAG 212
>UniRef50_Q830A7 Cluster: 2-hydroxy-3-oxopropionate reductase; n=7;
Firmicutes|Rep: 2-hydroxy-3-oxopropionate reductase -
Enterococcus faecalis (Streptococcus faecalis)
Length = 296
Score = 76.6 bits (180), Expect = 2e-13
Identities = 39/116 (33%), Positives = 59/116 (50%)
Frame = +1
Query: 43 VYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATL 222
VY + G+ G +++D +T P + ++I A E G DAPVSGG +GA+N TL
Sbjct: 74 VYFNETGIFQADLTGKIVVDLTTSTPTLAEKIAKKAAEVGAHALDAPVSGGDLGAKNGTL 133
Query: 223 AFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECM 390
M GG +E ++ LP+ K G G G GQ K+ N +++ T E +
Sbjct: 134 TIMVGGDQESYDTVLPIFKTFGKTFMLHGSAGKGQHTKMANQLMIAGTMTGLTEML 189
>UniRef50_Q5FQ06 Cluster: Putative oxidoreductase; n=1;
Gluconobacter oxydans|Rep: Putative oxidoreductase -
Gluconobacter oxydans (Gluconobacter suboxydans)
Length = 290
Score = 76.6 bits (180), Expect = 2e-13
Identities = 40/120 (33%), Positives = 62/120 (51%)
Frame = +1
Query: 52 GKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFM 231
G++G +A G L++D+ST+ P+ +A+E G DAP+SG A+ L +
Sbjct: 73 GENGALAALTPGKLVLDTSTVSPDQADAFASLAVEHGFSLLDAPMSGSTPEAETGDLVML 132
Query: 232 AGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMG 411
GG + +R+ P+L V+G H G GS KL N +MG T AE ++ G+ G
Sbjct: 133 VGGDEAVVKRAQPVLDVIGKLTIHAGPAGSAARLKLVVNGVMGATLNVIAEGVSYGLAAG 192
>UniRef50_Q1N6I0 Cluster: Putative oxidoreductase protein; n=1;
Oceanobacter sp. RED65|Rep: Putative oxidoreductase
protein - Oceanobacter sp. RED65
Length = 289
Score = 76.6 bits (180), Expect = 2e-13
Identities = 42/137 (30%), Positives = 73/137 (53%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
+++ + +++ V + GKD + ++ K G+L+ID +T + ++ LEK + + DA
Sbjct: 61 IIILCIGNDEDVRNTLTGKDSLYSNLKPGTLVIDHTTTSAELACEMQAKLLEKQVDYVDA 120
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSGG GA + L M GG+ ER+ + + H G IGSGQ+ K+ N + +
Sbjct: 121 PVSGGEQGAISGQLTIMCGGQALAAERAQGITQAYSKSFTHMGPIGSGQLTKMVNQICVA 180
Query: 361 ITGMATAECMNMGIKMG 411
A AE ++ G + G
Sbjct: 181 GLIEALAEGIHFGQQAG 197
>UniRef50_A3K497 Cluster: Probable 6-phosphogluconate dehydrogenase
protein; n=1; Sagittula stellata E-37|Rep: Probable
6-phosphogluconate dehydrogenase protein - Sagittula
stellata E-37
Length = 298
Score = 76.6 bits (180), Expect = 2e-13
Identities = 43/140 (30%), Positives = 76/140 (54%), Gaps = 3/140 (2%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYL--GKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFT 174
V++++L + +V V G+ G++ + G+L+ID+++ P +++ + +G
Sbjct: 62 VLLTMLPNGAIVRKVLDEGGEAGLLGQMQPGTLMIDTTSSPPEATRELAAVLNARGCHLV 121
Query: 175 DAPVSGGVMGAQNATLAFMAGGRKED-FERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNM 351
DAPVSG GA+ A L FM G + ER+ +L +G + FH G +G+G K NN
Sbjct: 122 DAPVSGARAGAEAADLVFMIGCDDDAVLERTRAVLSCLGNRLFHLGPVGAGHAMKALNNY 181
Query: 352 LMGITGMATAECMNMGIKMG 411
+ +A AE M +G ++G
Sbjct: 182 VSAAGYVAAAEAMIIGTEVG 201
>UniRef50_A0LDJ3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Magnetococcus sp. MC-1|Rep: 3-hydroxyisobutyrate
dehydrogenase - Magnetococcus sp. (strain MC-1)
Length = 292
Score = 76.6 bits (180), Expect = 2e-13
Identities = 44/129 (34%), Positives = 66/129 (51%)
Frame = +1
Query: 4 VVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 183
+V +++ +L+V G GV + G ++I++ST+ +Q + + G F DAP
Sbjct: 61 MVIMVSDPAALLEVLQGPVGVCSADLTGKVVINASTVSVEASQQAATLVEQVGGAFLDAP 120
Query: 184 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGI 363
VSG + AQ L F+AGG +R PLL MG+ CG +G G KL N+LM
Sbjct: 121 VSGSKIPAQTGKLVFLAGGHHAVIQRCEPLLLSMGSAVIPCGAVGDGTRMKLAMNLLMSG 180
Query: 364 TGMATAECM 390
A AE +
Sbjct: 181 MVQALAESL 189
>UniRef50_A0QUD5 Cluster: 3-hydroxyisobutyrate dehydrogenase family
protein; n=1; Mycobacterium smegmatis str. MC2 155|Rep:
3-hydroxyisobutyrate dehydrogenase family protein -
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Length = 326
Score = 76.2 bits (179), Expect = 3e-13
Identities = 38/122 (31%), Positives = 72/122 (59%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
V++++L ++ V VYLG DG+VA+A+ G++L+D STI P++ ++ G+ F A
Sbjct: 68 VLLTMLGTDDDVAQVYLGDDGLVANARAGAVLVDCSTISPDMSARVRARCDRAGVHFLAA 127
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PV+GG ++ LA G ++ FE + +L+V+ + G + ++ K+ +N+L+
Sbjct: 128 PVAGGPPVIESGGLAMAVSGDRQAFEHAADVLRVVAPNLIYVGPGDTSRLVKICHNLLVA 187
Query: 361 IT 366
T
Sbjct: 188 AT 189
>UniRef50_A1ZWM5 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Microscilla marina ATCC 23134|Rep: 3-hydroxyisobutyrate
dehydrogenase - Microscilla marina ATCC 23134
Length = 295
Score = 75.8 bits (178), Expect = 3e-13
Identities = 46/137 (33%), Positives = 69/137 (50%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
+V S+L S +VV V G+ G ++ K +L ID STI P A + + F +A
Sbjct: 59 IVFSMLASPQVVKAVAYGQTGFLSKMKSKALWIDCSTISPAFALASAQEASKHEVVFVEA 118
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PV+G A+NA L F+ GG ++ P +++MG K H G I K+ N L+
Sbjct: 119 PVAGTKSHAENAELVFLVGGGTTAIAQATPYMEMMGKKVVHIGAISKASALKILINYLLA 178
Query: 361 ITGMATAECMNMGIKMG 411
+A AE + +G K G
Sbjct: 179 QGMLAFAEALVVGEKQG 195
>UniRef50_A1UJF2 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=6; Actinomycetales|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Mycobacterium sp. (strain KMS)
Length = 272
Score = 75.8 bits (178), Expect = 3e-13
Identities = 39/126 (30%), Positives = 62/126 (49%)
Frame = +1
Query: 34 VLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQN 213
V +V G GV+A G+++ ST+ P+ ++I A + + DAPVSGG +
Sbjct: 70 VREVLYGDTGVLAGLAPGAMIAIHSTVHPDTCREIAEKAAAQNVSVIDAPVSGGAPAVEQ 129
Query: 214 ATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMN 393
L M GG + D E++ P+ H G +GSGQV K+ NN+L + +
Sbjct: 130 GKLLVMVGGEEADVEKARPVFATYADPIVHLGPLGSGQVTKILNNLLFTANLGSALSTLE 189
Query: 394 MGIKMG 411
+G +G
Sbjct: 190 LGESLG 195
>UniRef50_Q84H84 Cluster: Putative oxidoreductase; n=1; Arthrobacter
sp. BP2|Rep: Putative oxidoreductase - Arthrobacter sp.
BP2
Length = 278
Score = 75.4 bits (177), Expect = 4e-13
Identities = 45/134 (33%), Positives = 73/134 (54%), Gaps = 2/134 (1%)
Frame = +1
Query: 4 VVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKG-LGFTDA 180
+VS++ +DV LG+DG+++ K +I ST+DP+ ++ E G + A
Sbjct: 63 IVSMVRDYAQNVDVILGQDGLLSANPKNLTIIVMSTLDPDTMNELGQQVEEHGEVRLIAA 122
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCG-QIGSGQVAKLTNNMLM 357
VSGG GA+ TL+ MA G ++ + P +G+ F+ G + G+ Q AKL NN+++
Sbjct: 123 AVSGGSTGAEAGTLSIMASGAEDVVTAASPYFDAVGSNTFYYGSKPGNSQAAKLVNNLVL 182
Query: 358 GITGMATAECMNMG 399
GI A AE + G
Sbjct: 183 GINMNAVAEGLKFG 196
>UniRef50_Q3W9L4 Cluster: Putative uncharacterized protein; n=1;
Frankia sp. EAN1pec|Rep: Putative uncharacterized
protein - Frankia sp. EAN1pec
Length = 294
Score = 75.4 bits (177), Expect = 4e-13
Identities = 43/118 (36%), Positives = 61/118 (51%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
VV + ++ V DV L DGV+A G +++ STI P +++ A ++ + DA
Sbjct: 73 VVGICVVADADVEDVLLRADGVLAGMAAGGVVVIHSTIRPETCQRLATEAAKQEISIIDA 132
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNML 354
PVSGG A L M GG + R P+L+ H G +GSGQVAKL NN +
Sbjct: 133 PVSGGGDAAAQRRLLVMVGGEDDAVARCRPVLETFACPVIHLGPLGSGQVAKLVNNFV 190
>UniRef50_A0JXR2 Cluster: 2-hydroxy-3-oxopropionate reductase; n=2;
Arthrobacter|Rep: 2-hydroxy-3-oxopropionate reductase -
Arthrobacter sp. (strain FB24)
Length = 333
Score = 74.9 bits (176), Expect = 6e-13
Identities = 35/79 (44%), Positives = 47/79 (59%)
Frame = +1
Query: 175 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNML 354
DAPVSGG GA++ TLA M G ++DF+R LPL MG G +GSG +AK N ++
Sbjct: 136 DAPVSGGTKGAEDGTLAIMVGAGEQDFQRLLPLFNAMGGTVRRLGPLGSGSLAKACNQLI 195
Query: 355 MGITGMATAECMNMGIKMG 411
+G T A AE + + G
Sbjct: 196 VGTTTAALAEAAELAERSG 214
>UniRef50_A0GPK7 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=4; Burkholderia|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Burkholderia phytofirmans
PsJN
Length = 297
Score = 74.9 bits (176), Expect = 6e-13
Identities = 48/138 (34%), Positives = 67/138 (48%), Gaps = 1/138 (0%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEK-GLGFTD 177
+V+ L V V G DG+ A++G+ L+D ST+ P+ + E+ G + D
Sbjct: 64 IVMLCLADAAAVEAVAFGVDGLANRARRGATLVDHSTLAPSQTRAFARRWREQTGGDWID 123
Query: 178 APVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLM 357
APVSGG GA TLA MAGG E P+L+ A+ G G+GQ KL N ++
Sbjct: 124 APVSGGTSGAAAGTLAIMAGGDATLIETLTPILRGYAARVTRMGGSGAGQATKLANQTIV 183
Query: 358 GITGMATAECMNMGIKMG 411
T A AE + G
Sbjct: 184 MTTIAALAEATRLARHAG 201
>UniRef50_A6G049 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Plesiocystis pacifica SIR-1|Rep: 3-hydroxyisobutyrate
dehydrogenase - Plesiocystis pacifica SIR-1
Length = 307
Score = 74.5 bits (175), Expect = 8e-13
Identities = 37/121 (30%), Positives = 63/121 (52%), Gaps = 1/121 (0%)
Frame = +1
Query: 4 VVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 183
+++ + S+ V LG+ G +A +G+L+ID T + +Q+ +G F DAP
Sbjct: 72 IIACVGSDAATFAVLLGEGGALAGVGQGALVIDCGTTSLKLTEQLAAACEGEGASFLDAP 131
Query: 184 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQ-IGSGQVAKLTNNMLMG 360
++G +GA+ L M G +E R++PL ++MG H + +G GQ AK NM
Sbjct: 132 ITGSKLGAEGGKLTIMVAGEEEIVARAMPLFEIMGKHTVHVSERLGDGQRAKYCLNMTQA 191
Query: 361 I 363
+
Sbjct: 192 V 192
>UniRef50_A3JU55 Cluster: Predicted dehydrogenase, with
NAD(P)-binding Rossmann-fold domain; n=2; Bacteria|Rep:
Predicted dehydrogenase, with NAD(P)-binding
Rossmann-fold domain - Rhodobacterales bacterium
HTCC2150
Length = 302
Score = 74.1 bits (174), Expect = 1e-12
Identities = 46/138 (33%), Positives = 68/138 (49%), Gaps = 1/138 (0%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
V V ++ ++V V G+ G++AH KG +I S+TI P ++I + G+ D
Sbjct: 60 VFVMVMNGDQVK-SVLFGEGGLLAHMPKGGAVILSATIKPVEAEEIGAAMADSGIHLIDT 118
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCG-QIGSGQVAKLTNNMLM 357
PVSGG GAQ TL MA G E + P+++ + A + G + G GQ K L+
Sbjct: 119 PVSGGFPGAQGGTLTMMAAGVDEVLDTYAPVMEAVSATIWCVGTEAGQGQTVKACLQSLL 178
Query: 358 GITGMATAECMNMGIKMG 411
G AT E + K G
Sbjct: 179 GAMFSATFEASVLAAKAG 196
>UniRef50_Q12H32 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=1; Polaromonas sp. JS666|Rep:
6-phosphogluconate dehydrogenase, NAD-binding precursor
- Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 297
Score = 73.7 bits (173), Expect = 1e-12
Identities = 42/136 (30%), Positives = 68/136 (50%)
Frame = +1
Query: 4 VVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 183
V+ +T + V G DGV++ A G ++ID+ST +P +++ + E+G+ DAP
Sbjct: 62 VIICVTGSPQVEQTLSGPDGVLSRALAGLIVIDTSTSEPESTRRLAALCAERGVTLVDAP 121
Query: 184 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGI 363
++ + A+ L M G + F++ P+L FH G G+G V KL NN +
Sbjct: 122 LARTPVEAELGRLNTMVGAEQAVFDKIRPVLAAYCENIFHVGGPGAGHVIKLLNNFIGQA 181
Query: 364 TGMATAECMNMGIKMG 411
ATAE +G G
Sbjct: 182 ICTATAEAFAVGALAG 197
>UniRef50_Q121N3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=19;
Burkholderiales|Rep: 3-hydroxyisobutyrate dehydrogenase
- Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 298
Score = 73.7 bits (173), Expect = 1e-12
Identities = 42/138 (30%), Positives = 68/138 (49%), Gaps = 1/138 (0%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
VVVS++ + DV + GV + K GS+ + ST+DP + G+ + DA
Sbjct: 62 VVVSVVVNAAQTEDVLWSEQGVASAMKSGSVFVMCSTVDPQWSIATEARLDKLGIHYVDA 121
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQ-IGSGQVAKLTNNMLM 357
P+SGG A + M+ R +E++ +L M K + G G+G K+ N +L
Sbjct: 122 PISGGAAKAAAGQMTVMSSARPAAYEKAGDVLAAMAGKVYRLGDCAGAGSKVKIINQLLA 181
Query: 358 GITGMATAECMNMGIKMG 411
G+ A AE M +G++ G
Sbjct: 182 GVHIAAAAEAMALGLREG 199
>UniRef50_A7IE35 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Proteobacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Xanthobacter sp. (strain Py2)
Length = 330
Score = 73.7 bits (173), Expect = 1e-12
Identities = 40/138 (28%), Positives = 64/138 (46%), Gaps = 1/138 (0%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
VVVS++ + + G DGV G++ + S+T+DP + + + G + DA
Sbjct: 91 VVVSVVVNAAQTETILFGADGVAQTLADGAVFLSSATMDPEIARTLAARLEATGRLYLDA 150
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQI-GSGQVAKLTNNMLM 357
P+SGG A L +A G F ++ P L M AK + G G G K+ N +L
Sbjct: 151 PISGGAQRAAEGALTILASGSPAAFAKARPALDAMAAKLYELGDAPGQGAAFKMINQLLA 210
Query: 358 GITGMATAECMNMGIKMG 411
G+ A +E + + G
Sbjct: 211 GVHIAAASEAVAFAARQG 228
>UniRef50_A3LTC4 Cluster: 3-hydroxyisobutyrate dehydrogenase-like
protein; n=6; Saccharomycetales|Rep:
3-hydroxyisobutyrate dehydrogenase-like protein - Pichia
stipitis (Yeast)
Length = 355
Score = 73.7 bits (173), Expect = 1e-12
Identities = 44/110 (40%), Positives = 61/110 (55%), Gaps = 5/110 (4%)
Frame = +1
Query: 97 IDSSTIDPNVPKQIFPIALEK--GLGFTDAPVSGGVMGAQNATLAFM-AGGRKEDFERSL 267
+DSSTID +++ ++ G F D PVSGGV GA+ ATL+FM + E L
Sbjct: 130 LDSSTIDIPTSREVHEFVKKELPGADFIDTPVSGGVAGARKATLSFMLSRPNNESISADL 189
Query: 268 -PLLKVMGAKQFHCGQI-GSGQVAKLTNNMLMGITGMATAECMNMGIKMG 411
LL MGA F CG+ G+G AKL+NN L+ +T +A A+ + G
Sbjct: 190 RTLLNKMGANIFACGETHGAGLAAKLSNNYLLAVTNLAVADSFQLAKSFG 239
>UniRef50_A0GI22 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Burkholderia phytofirmans PsJN|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Burkholderia phytofirmans PsJN
Length = 355
Score = 73.3 bits (172), Expect = 2e-12
Identities = 37/83 (44%), Positives = 49/83 (59%)
Frame = +1
Query: 163 LGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLT 342
+G+ DAPVSGGV GA TLA MAGG D E PLL ++ H G +G+GQ AKL
Sbjct: 175 IGWIDAPVSGGVAGATAGTLAVMAGGAAADVEAVKPLLGAYASRVTHMGDVGAGQTAKLC 234
Query: 343 NNMLMGITGMATAECMNMGIKMG 411
N ++ T A AE +++ + G
Sbjct: 235 NQTIVTATLAAIAEAVSLAQRSG 257
>UniRef50_Q4Q9Z1 Cluster: Dehydrogenase-like protein; n=6;
Trypanosomatidae|Rep: Dehydrogenase-like protein -
Leishmania major
Length = 431
Score = 73.3 bits (172), Expect = 2e-12
Identities = 41/130 (31%), Positives = 66/130 (50%)
Frame = +1
Query: 22 SNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVM 201
S KV+L+ + +V +A+ G +++D +T+D + ++ A +G F DAP+SG
Sbjct: 88 SRKVLLE---DSEALVTNARPGQIIVDHTTVDMELSRECAHEAERRGAVFLDAPMSGSPK 144
Query: 202 GAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATA 381
A N L M GG E +R P+ ++ H G GSG AKL + L+ A A
Sbjct: 145 QAFNNQLVLMVGGPAEQVQRVSPIFRMYADHIHHMGANGSGTAAKLLSQALVASHNAAAA 204
Query: 382 ECMNMGIKMG 411
E M + ++G
Sbjct: 205 EAMTIANRLG 214
>UniRef50_Q4WXG9 Cluster: 3-hydroxyisobutyrate dehydrogenase,
putative; n=1; Aspergillus fumigatus|Rep:
3-hydroxyisobutyrate dehydrogenase, putative -
Aspergillus fumigatus (Sartorya fumigata)
Length = 317
Score = 73.3 bits (172), Expect = 2e-12
Identities = 51/137 (37%), Positives = 70/137 (51%), Gaps = 3/137 (2%)
Frame = +1
Query: 10 SILTSNKVVLDVYLGKD-GVVAHAKKGSLLIDSSTIDPNVPKQIFPIALE--KGLGFTDA 180
+++ + V VYL GV+ + +L+D STID + + K F DA
Sbjct: 84 TMVPEGRHVRSVYLDSHAGVLTTSVDDKILVDCSTIDTATSMDVGAAVCQNSKTAAFYDA 143
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSGG +GA TL FM G ++D P L+++ F CG G AKL NN G
Sbjct: 144 PVSGGSLGAVAGTLTFMVGCVEDD-----PNLELL---IFPCGGFLLGLTAKLCNNYCSG 195
Query: 361 ITGMATAECMNMGIKMG 411
+ +ATAE MN+GIK G
Sbjct: 196 LIAIATAEAMNIGIKSG 212
>UniRef50_Q7NR40 Cluster: Probable 3-hydroxyisobutyrate
dehydrogenase; n=1; Chromobacterium violaceum|Rep:
Probable 3-hydroxyisobutyrate dehydrogenase -
Chromobacterium violaceum
Length = 296
Score = 72.9 bits (171), Expect = 2e-12
Identities = 39/129 (30%), Positives = 63/129 (48%)
Frame = +1
Query: 4 VVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 183
V ++LT + + + G +G+ + G L+D T P + A G +AP
Sbjct: 67 VATVLTDSAALRALLFGDNGIASAPAAGRRLVDLGTHQPTQLAALGAEAAAAGWPLVEAP 126
Query: 184 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGI 363
++G V A + TL F+ GG + D E + PLL +G H G +G+G AKL N+L+G+
Sbjct: 127 MTGSVHDASHGTLHFLVGGAEADVEWASPLLWALGRGVHHLGGLGAGNTAKLALNLLVGV 186
Query: 364 TGMATAECM 390
E +
Sbjct: 187 MAGGLGEAI 195
>UniRef50_A2C1U6 Cluster: 3-hydroxyisobutyrate dehydrogenase and
related beta-hydroxyacid dehydrogenases; n=2;
Prochlorococcus marinus|Rep: 3-hydroxyisobutyrate
dehydrogenase and related beta-hydroxyacid
dehydrogenases - Prochlorococcus marinus (strain NATL1A)
Length = 287
Score = 72.9 bits (171), Expect = 2e-12
Identities = 42/128 (32%), Positives = 62/128 (48%)
Frame = +1
Query: 16 LTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGG 195
+T + V V G +GV K S +ID STI P+ I E+ + + D PVSGG
Sbjct: 60 VTDDNAVESVLFGDNGVSGSLKPNSFVIDFSTISPDKSISIHKRLGEQNIFYVDCPVSGG 119
Query: 196 VMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMA 375
GA N +L+ G ++D + +V+G + +G GQ K N +L+ T A
Sbjct: 120 TEGAHNGSLSLFIGASEKDCLSFENIFQVLGKSINYFNGVGKGQQVKALNQILVAGTYAA 179
Query: 376 TAECMNMG 399
AE M +G
Sbjct: 180 VAEAMELG 187
>UniRef50_Q9JYH6 Cluster: 3-hydroxyacid dehydrogenase; n=5;
Proteobacteria|Rep: 3-hydroxyacid dehydrogenase -
Neisseria meningitidis serogroup B
Length = 289
Score = 72.5 bits (170), Expect = 3e-12
Identities = 45/138 (32%), Positives = 68/138 (49%), Gaps = 1/138 (0%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLG-KDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTD 177
V+ +++ V D+ G +DG+ G ++++ STI P + + G F +
Sbjct: 65 VIFLMVSDYAAVCDILNGVRDGLA-----GKIIVNMSTISPTENLAVKALVEAAGGQFAE 119
Query: 178 APVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLM 357
APVSG V A N TL + GG + + ++G K FH G +G G AKL N L+
Sbjct: 120 APVSGSVGPATNGTLLILFGGSEAVLNPLQKIFSLVGKKTFHFGDVGKGSGAKLVLNSLL 179
Query: 358 GITGMATAECMNMGIKMG 411
GI G A +E M M + G
Sbjct: 180 GIFGEAYSEAMLMARQFG 197
>UniRef50_Q5LQR0 Cluster: 6-phosphogluconate dehydrogenase domain
protein; n=14; Proteobacteria|Rep: 6-phosphogluconate
dehydrogenase domain protein - Silicibacter pomeroyi
Length = 302
Score = 72.5 bits (170), Expect = 3e-12
Identities = 44/128 (34%), Positives = 65/128 (50%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
V++ + TS +V +Y G DGV+A ++G ++ID T P ++I KG + DA
Sbjct: 69 VMLCMGTSAQVESRIY-GDDGVLAGTREGQVVIDFGTSLPASTRRIGGDLAGKGATYLDA 127
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
P+ A++ L M G K F+R P+L +G FH G +G+G KL NN
Sbjct: 128 PLGRTPAHARDGLLNIMCSGDKATFDRVKPVLHTLGENVFHLGALGNGHTIKLINNCYSM 187
Query: 361 ITGMATAE 384
T A AE
Sbjct: 188 TTACAMAE 195
>UniRef50_A0G5G5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Proteobacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Burkholderia phymatum
STM815
Length = 306
Score = 72.5 bits (170), Expect = 3e-12
Identities = 43/137 (31%), Positives = 66/137 (48%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
VV+ L +KVV V G GV+AH + +++D ST + ++ + G+ + DA
Sbjct: 59 VVMMSLPDSKVVEAVVEGDGGVLAHCRARQIVVDLSTAAASSTIRLARRFTQSGVQYVDA 118
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
+SGG A+ L M GG + + +K H G+ G+G KL NN L
Sbjct: 119 GISGGAAAAEKGALTLMVGGDASAVDALKWAFAPISSKVAHMGESGAGHTTKLLNNFLNA 178
Query: 361 ITGMATAECMNMGIKMG 411
++ A+AE M G K G
Sbjct: 179 VSLSASAEVMVAGKKAG 195
>UniRef50_Q8TT25 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Methanosarcina|Rep: 3-hydroxyisobutyrate dehydrogenase -
Methanosarcina acetivorans
Length = 300
Score = 71.7 bits (168), Expect = 5e-12
Identities = 43/137 (31%), Positives = 66/137 (48%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
++++ LT V V G+DG++ AKKG L ID STIDP+ + A + GL D
Sbjct: 68 IIMTSLTDEAAVNSVAFGEDGLLNGAKKGCLWIDLSTIDPSSSVKHAEAAKKAGLERLDT 127
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PV G A L + GG +E + L +G + G G+G KL N+ +G
Sbjct: 128 PVVGSKDLASKGELIILVGGSQEVLRKHEKFLNKLGKSVIYLGADGNGHKMKLAINLHLG 187
Query: 361 ITGMATAECMNMGIKMG 411
+ + +E + K+G
Sbjct: 188 LLAESFSEALVFSQKLG 204
>UniRef50_A1WM48 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Verminephrobacter eiseniae EF01-2|Rep:
3-hydroxyisobutyrate dehydrogenase - Verminephrobacter
eiseniae (strain EF01-2)
Length = 301
Score = 71.3 bits (167), Expect = 7e-12
Identities = 43/132 (32%), Positives = 62/132 (46%)
Frame = +1
Query: 16 LTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGG 195
L V V +DG++ K+ ++D STI P +G+ + D+PVSGG
Sbjct: 68 LPDGPAVQHVISAQDGLL-QGKRVKCVVDLSTIGPRAAVAASQALGARGIAYVDSPVSGG 126
Query: 196 VMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMA 375
+ GA+ TLA M + ++ P+LK G + G GQ KL NN+L
Sbjct: 127 IGGAERGTLAVMTACPQPLYDELAPVLKNFGRLFYMGAGPGLGQTMKLANNLLSAAAVAI 186
Query: 376 TAECMNMGIKMG 411
T+E M MG K G
Sbjct: 187 TSEAMAMGAKAG 198
>UniRef50_A1WJN2 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Proteobacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Verminephrobacter eiseniae
(strain EF01-2)
Length = 297
Score = 71.3 bits (167), Expect = 7e-12
Identities = 43/132 (32%), Positives = 66/132 (50%)
Frame = +1
Query: 16 LTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGG 195
L S +V + +DG++A A+ G +++D T + +Q+ + F DAPV+
Sbjct: 71 LPSGAIVAQLCRQQDGLLASARPGHIVVDLGTSSVDGTRQLAAEFAARQAKFADAPVART 130
Query: 196 VMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMA 375
AQ TLA M G E F PL+ + CG +G GQV K+ NNM++ T +A
Sbjct: 131 RAAAQAGTLAVMVGADPELFGVIEPLIATFASDIALCGPVGCGQVLKILNNMILFETVVA 190
Query: 376 TAECMNMGIKMG 411
+E +G K G
Sbjct: 191 ISEAKAIGEKAG 202
>UniRef50_Q656T5 Cluster: Oxidoreductase-like; n=3; Oryza
sativa|Rep: Oxidoreductase-like - Oryza sativa subsp.
japonica (Rice)
Length = 341
Score = 71.3 bits (167), Expect = 7e-12
Identities = 42/137 (30%), Positives = 65/137 (47%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
V ++L + ++V G +G G +D ST+D K I G F +A
Sbjct: 109 VTFAMLADPESAVEVACGANGAAQGMAPGKGYVDVSTVDAATSKLIGKHITSTGASFLEA 168
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSG A++ L F+ G + + R LL VMG +F G +G G KL NM+MG
Sbjct: 169 PVSGSKKPAEDGLLIFLTAGDESLYNRVASLLDVMGKSRFFLGDVGKGADMKLVVNMVMG 228
Query: 361 ITGMATAECMNMGIKMG 411
++ +E + + K+G
Sbjct: 229 SMMVSFSEGLLLSEKVG 245
>UniRef50_Q7WG50 Cluster: Probable oxidoreductase; n=1; Bordetella
bronchiseptica|Rep: Probable oxidoreductase - Bordetella
bronchiseptica (Alcaligenes bronchisepticus)
Length = 316
Score = 70.9 bits (166), Expect = 9e-12
Identities = 44/138 (31%), Positives = 66/138 (47%), Gaps = 1/138 (0%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
+V+++L + + G DG + G+L I+ STI P I E+G+ D+
Sbjct: 62 LVIAMLPTATHIQAALEGADGALQGMDPGALFINMSTILPQETDLIAQRLAERGMRMLDS 121
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PV M AQ TL +A G +D R+ L MG + CG++G G K+ NN MG
Sbjct: 122 PVGRSAMEAQRGTLLILASGSAQDKARARDALLCMGNQVIDCGEVGGGSRVKVVNN-FMG 180
Query: 361 IT-GMATAECMNMGIKMG 411
I+ TAE + + G
Sbjct: 181 ISLNALTAEALTLAEASG 198
>UniRef50_Q46TQ0 Cluster: UDP-glucose/GDP-mannose
dehydrogenase:Prephenate dehydrogenase:NADP
oxidoreductase, coenzyme
F420-dependent:6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Ralstonia eutropha JMP134|Rep:
UDP-glucose/GDP-mannose dehydrogenase:Prephenate
dehydrogenase:NADP oxidoreductase, coenzyme
F420-dependent:6-phosphogluconate dehydrogenase,
NAD-binding - Ralstonia eutropha (strain JMP134)
(Alcaligenes eutrophus)
Length = 294
Score = 70.9 bits (166), Expect = 9e-12
Identities = 36/112 (32%), Positives = 58/112 (51%)
Frame = +1
Query: 76 AKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDF 255
A+ G+L ID+ST+ P + P+ + + + VSG A+ A L + G + +
Sbjct: 81 ARPGALYIDTSTVSPAASAAVAPLLAARDIAYLRVTVSGNNHMAEAAKLTALVSGPADAY 140
Query: 256 ERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMG 411
ER PLL +G QF+ G ++ KL N+L+ +TG AE + +G K G
Sbjct: 141 ERIKPLLAALGPAQFYLGDAEQARLMKLVVNLLIALTGGMLAEALTLGSKGG 192
>UniRef50_O33730 Cluster: Uncharacterized oxidoreductase Sfri_1503;
n=167; Bacteria|Rep: Uncharacterized oxidoreductase
Sfri_1503 - Shewanella frigidimarina (strain NCIMB 400)
Length = 291
Score = 70.9 bits (166), Expect = 9e-12
Identities = 38/137 (27%), Positives = 67/137 (48%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
+V + + ++ + V LG+ G+V G++L+D +T +V ++I + F DA
Sbjct: 61 IVFTCVGNDDDLRQVVLGEHGIVHGMHAGAILVDHTTASADVAREIAAYIEPLNIAFLDA 120
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSGG GA+N L M GG + F+ P++ G +G+GQ+ K+ N + +
Sbjct: 121 PVSGGQAGAENGALTVMMGGDQAHFDTVKPVISAYSRCAELLGPVGAGQLTKMVNQICIA 180
Query: 361 ITGMATAECMNMGIKMG 411
AE ++ G
Sbjct: 181 GVVQGLAEGLHFAKSAG 197
>UniRef50_Q3W3N3 Cluster: Putative uncharacterized protein; n=1;
Frankia sp. EAN1pec|Rep: Putative uncharacterized
protein - Frankia sp. EAN1pec
Length = 315
Score = 70.5 bits (165), Expect = 1e-11
Identities = 39/130 (30%), Positives = 61/130 (46%)
Frame = +1
Query: 22 SNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVM 201
S++ V V G G++ + GSL++ ST P + A +G+ DAPVS G
Sbjct: 79 SDEDVRTVVAGPGGLLETMRSGSLVVIHSTCSPRTCVDLAARARGRGITVLDAPVSNGAP 138
Query: 202 GAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATA 381
L +AGG + D +R P+ ++ G + G +GS Q+ KL NN L + A
Sbjct: 139 DESGRQLVVLAGGDRRDVDRCAPVFELFGRTVVYTGDVGSAQLTKLVNNALFIVHRSAAI 198
Query: 382 ECMNMGIKMG 411
E + +G
Sbjct: 199 EALRAAGTLG 208
>UniRef50_A1GFG2 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Salinispora arenicola CNS205|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Salinispora arenicola CNS205
Length = 315
Score = 70.5 bits (165), Expect = 1e-11
Identities = 41/129 (31%), Positives = 61/129 (47%), Gaps = 1/129 (0%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKD-GVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTD 177
+V+S+L + V+L D G + G+L +D ST+ P +++ ++G F D
Sbjct: 60 LVISMLRDVEAGRSVWLDPDVGALTSLAPGTLAVDCSTVTPTFSRELAACCAQRGAEFLD 119
Query: 178 APVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLM 357
APV G A TL F+AGG R P+L+ +G H G G+G KL N L
Sbjct: 120 APVLGSRPQADAGTLIFLAGGDLAVLHRIEPVLRQVGGAVHHMGPAGTGTQMKLLTNSLF 179
Query: 358 GITGMATAE 384
+ AE
Sbjct: 180 AVQVATVAE 188
>UniRef50_A5FTT0 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Alphaproteobacteria|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Acidiphilium cryptum (strain JF-5)
Length = 305
Score = 69.3 bits (162), Expect = 3e-11
Identities = 39/109 (35%), Positives = 58/109 (53%)
Frame = +1
Query: 85 GSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERS 264
G+LLI+ S+ P V ++I + DAPVSGGV A+ L+ M GG +D R+
Sbjct: 87 GALLIEMSSGIPGVTRRIAAGLEAAKVAMIDAPVSGGVARAKTGDLSIMTGGSADDCARA 146
Query: 265 LPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMG 411
LL++MG H G IG+GQ K NN++ + E + +G + G
Sbjct: 147 ETLLRLMGTTITHVGDIGAGQAMKALNNLVSAGGFLIGVEALLIGQRFG 195
>UniRef50_Q1EPJ1 Cluster: 6-phosphogluconate dehydrogenase
NAD-binding domain-containing protein; n=8;
Magnoliophyta|Rep: 6-phosphogluconate dehydrogenase
NAD-binding domain-containing protein - Musa acuminata
(Banana)
Length = 314
Score = 69.3 bits (162), Expect = 3e-11
Identities = 37/110 (33%), Positives = 62/110 (56%)
Frame = +1
Query: 61 GVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGG 240
G +A G +L+D ++ DP + +++ A +G DAPVSGG +GA++ TLA +AGG
Sbjct: 95 GALAAIPPGGVLVDCTSSDPALAREVAAAARARGCWAVDAPVSGGDVGARDGTLAILAGG 154
Query: 241 RKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECM 390
+ PL + +G + G GSGQ +K+ N + +G T + +E +
Sbjct: 155 DEGVVHWLSPLFEALGRATW-MGPAGSGQSSKIANQITIGGTILGLSEAI 203
>UniRef50_Q0BTJ3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
Granulibacter bethesdensis CGDNIH1|Rep:
2-hydroxy-3-oxopropionate reductase - Granulobacter
bethesdensis (strain ATCC BAA-1260 / CGDNIH1)
Length = 293
Score = 68.9 bits (161), Expect = 4e-11
Identities = 44/127 (34%), Positives = 66/127 (51%)
Frame = +1
Query: 4 VVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 183
V ++ S+ D L V A+ G++L+ SS Q ++ + DAP
Sbjct: 62 VALLMVSDGPACDAVLETGFVDTMAQNGTVLVMSSIEPWRARAQAKKVSPRF---YVDAP 118
Query: 184 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGI 363
VSGG GA+N TLA MAGG + R P+ +G + G IG+GQ+AKL N +++G+
Sbjct: 119 VSGGEGGARNGTLAIMAGGEEAVLNRLAPVFAALG-RMTRIGDIGAGQLAKLANQLIVGV 177
Query: 364 TGMATAE 384
T A +E
Sbjct: 178 TIGAVSE 184
>UniRef50_Q89M84 Cluster: Blr4309 protein; n=6;
Bradyrhizobiaceae|Rep: Blr4309 protein - Bradyrhizobium
japonicum
Length = 293
Score = 68.5 bits (160), Expect = 5e-11
Identities = 41/136 (30%), Positives = 69/136 (50%)
Frame = +1
Query: 4 VVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 183
VV+++ ++ V+LG G AK G++ I+ ST+ + +++ +GL + D P
Sbjct: 61 VVTMVADDEASRAVWLGPKGAAKTAKAGTIAIECSTVSYDHAREMGRELNARGLIYIDCP 120
Query: 184 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGI 363
V+G A L + G D ER+ P L+ +G+ H G +GSG V KL NN++ I
Sbjct: 121 VTGLPDAAAAGKLTLLVGADAADLERARPYLEPIGSTIRHFGAVGSGTVYKLINNLMGAI 180
Query: 364 TGMATAECMNMGIKMG 411
AE + + + G
Sbjct: 181 QIAGLAEGLAIAEQAG 196
>UniRef50_A0K0Z6 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=2; Micrococcineae|Rep:
6-phosphogluconate dehydrogenase, NAD-binding precursor
- Arthrobacter sp. (strain FB24)
Length = 301
Score = 68.5 bits (160), Expect = 5e-11
Identities = 39/107 (36%), Positives = 56/107 (52%), Gaps = 1/107 (0%)
Frame = +1
Query: 94 LIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLP- 270
+ID++T +P KQ+ +A +G F DAPVSGG GA + +L+ GG + P
Sbjct: 89 IIDTTTSEPATSKQMAHLADTQGAAFVDAPVSGGRDGAASGSLSAFVGGTDAALAAAEPV 148
Query: 271 LLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMG 411
LL + G K H G GSG V KL NN+L ++ E + + G
Sbjct: 149 LLALTGGKYSHIGGPGSGNVVKLLNNVLAAANLVSVGEALGVAKAYG 195
>UniRef50_A0K107 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
Arthrobacter sp. FB24|Rep: 2-hydroxy-3-oxopropionate
reductase - Arthrobacter sp. (strain FB24)
Length = 302
Score = 68.1 bits (159), Expect = 7e-11
Identities = 43/135 (31%), Positives = 65/135 (48%), Gaps = 5/135 (3%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSL----LIDSSTIDPNVPKQIFPIALEK-GL 165
VV+++L V + G+DG++A K + L+ T+ P + L GL
Sbjct: 70 VVLTVLPDLPQVAALLPGEDGLLAGWKAAGIEHPVLVIHGTVSPVAVAEFADDCLRNWGL 129
Query: 166 GFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTN 345
DAP+SGG +GA+ L+ M GG E ER PL + + H G+ G+G K N
Sbjct: 130 TVVDAPLSGGTIGAEEGRLSIMVGGPAEAVERLTPLFGLYSSTAVHFGKTGAGSTVKACN 189
Query: 346 NMLMGITGMATAECM 390
+++ T A AE M
Sbjct: 190 QIVVAATVNALAEAM 204
>UniRef50_A6F020 Cluster: Putative uncharacterized protein; n=1;
Marinobacter algicola DG893|Rep: Putative
uncharacterized protein - Marinobacter algicola DG893
Length = 286
Score = 67.7 bits (158), Expect = 9e-11
Identities = 37/109 (33%), Positives = 55/109 (50%)
Frame = +1
Query: 85 GSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERS 264
GS ++ +T P + + +KGLGF DAPV G GA+ L + GG + +
Sbjct: 84 GSTVVILATNSPKTMQVLAAECEDKGLGFVDAPVVFGRQGAKEGQLGSLCGGDDKQVAKI 143
Query: 265 LPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMG 411
P+L+ H G +GSGQVAK NNML +A E +++ + G
Sbjct: 144 TPVLESYSKAVHHVGPVGSGQVAKACNNMLHWAACVANFEVLSLAKRYG 192
>UniRef50_Q3W9W7 Cluster: 6-phosphogluconate dehydrogenase, NAD
binding domain; n=2; Frankia sp. EAN1pec|Rep:
6-phosphogluconate dehydrogenase, NAD binding domain -
Frankia sp. EAN1pec
Length = 286
Score = 67.3 bits (157), Expect = 1e-10
Identities = 37/107 (34%), Positives = 56/107 (52%), Gaps = 1/107 (0%)
Frame = +1
Query: 94 LIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPL 273
++D+STI + ++I + G+G+ DAPVSGGV GA+ TL M G + R P+
Sbjct: 88 VVDTSTIGVSAAQRITDLLAASGIGYVDAPVSGGVTGARARTLTVMYAGTDDACARVEPV 147
Query: 274 LKVMGAKQFHCG-QIGSGQVAKLTNNMLMGITGMATAECMNMGIKMG 411
L + ++ G + G Q KL NN L + AT+E + G G
Sbjct: 148 LAALSDRRRRVGDRPGLAQALKLANNFLAAVALAATSEAVAFGTSAG 194
>UniRef50_A5P0V0 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=3; Rhizobiales|Rep:
6-phosphogluconate dehydrogenase, NAD-binding precursor
- Methylobacterium sp. 4-46
Length = 299
Score = 66.9 bits (156), Expect = 2e-10
Identities = 42/138 (30%), Positives = 66/138 (47%), Gaps = 1/138 (0%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
+VV+ + V+ +G + + +I +T P + + G F DA
Sbjct: 66 MVVNAAQAEAVLFGGGAPAEGALEVLAPDAAVILMATCPPQAVEGLAARVAAAGRRFVDA 125
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCG-QIGSGQVAKLTNNMLM 357
PVSGGV+GA+ +L MA E F PLL +GA+ FH G + G G K N +L
Sbjct: 126 PVSGGVVGAEAGSLTVMAAAPAEVFGAVRPLLDAVGARIFHVGTRPGQGATVKAVNQLLC 185
Query: 358 GITGMATAECMNMGIKMG 411
G+ A AE +++ ++G
Sbjct: 186 GVHIAAAAEALSLAERVG 203
>UniRef50_O66454 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3;
cellular organisms|Rep: 3-hydroxyisobutyrate
dehydrogenase - Aquifex aeolicus
Length = 288
Score = 66.5 bits (155), Expect = 2e-10
Identities = 41/136 (30%), Positives = 66/136 (48%)
Frame = +1
Query: 4 VVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 183
V I+ ++ +V G+ G+V KG +ID +T ++ + + G + DAP
Sbjct: 61 VFVIVFDSQASEEVIFGEKGLVKGDIKGKTVIDMTTNHYLYAQKAYEELKKLGAFYLDAP 120
Query: 184 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGI 363
V G V+ A L + GG KE FE + PL + ++ G+ G G KL NN+++G
Sbjct: 121 VLGSVIPALKGELTIVVGGDKEKFEENKPLFEKFCRAIYYLGEAGMGSKMKLVNNIVLGG 180
Query: 364 TGMATAECMNMGIKMG 411
AE + +G K G
Sbjct: 181 IMEVLAEAIAIGEKAG 196
>UniRef50_Q0KC92 Cluster: 3-Hydroxyisobutyrate dehydrogenase; n=1;
Ralstonia eutropha H16|Rep: 3-Hydroxyisobutyrate
dehydrogenase - Ralstonia eutropha (strain ATCC 17699 /
H16 / DSM 428 / Stanier 337)(Cupriavidus necator (strain
ATCC 17699 / H16 / DSM 428 / Stanier337))
Length = 305
Score = 66.5 bits (155), Expect = 2e-10
Identities = 38/137 (27%), Positives = 65/137 (47%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
VV S + + + D++L GV A + +D ST+ P+ ++ +G F A
Sbjct: 71 VVFSTIFDDGGLRDLFLASGGVAGAATADKVFVDMSTVSPDASAEVAAALARRGAAFLRA 130
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSG V A +A L+ G + F+ P+L + A+Q + G +V KL NM++
Sbjct: 131 PVSGTVSLAASAQLSCFVSGPRPAFDAVQPVLACLTARQSYVGGADEARVIKLMINMMVF 190
Query: 361 ITGMATAECMNMGIKMG 411
++ E + G + G
Sbjct: 191 MSTAVIGEGLAFGARAG 207
>UniRef50_A7DSF1 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
Candidatus Nitrosopumilus maritimus SCM1|Rep:
2-hydroxy-3-oxopropionate reductase - Candidatus
Nitrosopumilus maritimus SCM1
Length = 292
Score = 66.5 bits (155), Expect = 2e-10
Identities = 39/128 (30%), Positives = 61/128 (47%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
+V+ ++ V +V ++G++ K ++ D STIDP+ K I LE G+ D
Sbjct: 60 LVIIVVKDADAVKEVSFEREGIIKSENKKLIVADMSTIDPSESKNISDKFLEFGIHKLDI 119
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PV GG A L MA G KE FE + + + K F G+ G KL N+ +
Sbjct: 120 PVMGGPNVAITGDLVMMASGNKESFEECKKVFEKIANKVFFLGEKGVAHSIKLAMNLQIT 179
Query: 361 ITGMATAE 384
+ +A +E
Sbjct: 180 MLALALSE 187
>UniRef50_A6VLT0 Cluster: 2-hydroxy-3-oxopropionate reductase; n=2;
Pasteurellaceae|Rep: 2-hydroxy-3-oxopropionate reductase
- Actinobacillus succinogenes 130Z
Length = 289
Score = 66.1 bits (154), Expect = 3e-10
Identities = 39/136 (28%), Positives = 69/136 (50%)
Frame = +1
Query: 4 VVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 183
V+ ++ ++ V++ L ++ V A KG L+++ ST+ P +Q+ + + G F +AP
Sbjct: 65 VIFVMVADFPVIESLLSEE--VLTALKGKLVVNMSTVSPTQNQQLEFLLAKHGAEFIEAP 122
Query: 184 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGI 363
VSG A+ L +A G++E E+ PL + F+ G++G KL N L+GI
Sbjct: 123 VSGSSKVAEAGKLLVLAAGKEEIVEQLKPLFAAFSTQTFYYGEVGKAGGVKLMINSLLGI 182
Query: 364 TGMATAECMNMGIKMG 411
A E + + G
Sbjct: 183 FIQAYGEALLFAEQFG 198
>UniRef50_Q9L7S0 Cluster: Uncharacterized oxidoreductase yihU; n=24;
Gammaproteobacteria|Rep: Uncharacterized oxidoreductase
yihU - Salmonella typhimurium
Length = 298
Score = 66.1 bits (154), Expect = 3e-10
Identities = 40/127 (31%), Positives = 58/127 (45%)
Frame = +1
Query: 4 VVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 183
V+++L + +V V G+ GV + +L+ID STI P + KG D P
Sbjct: 61 VITMLPNGDLVRSVLFGEQGVCETLSREALVIDMSTIHPLQTDNLIADMQSKGFSMMDVP 120
Query: 184 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGI 363
+ A TL +AGG E ER+ P+L MG + + G G G KL NN +
Sbjct: 121 IGRTSDNAITGTLLLLAGGTAEQVERATPVLMAMGNELVNTGGPGMGIRVKLINNYMSIA 180
Query: 364 TGMATAE 384
+AE
Sbjct: 181 LNALSAE 187
>UniRef50_Q019Z7 Cluster: Oxidoreductase-like; n=1; Ostreococcus
tauri|Rep: Oxidoreductase-like - Ostreococcus tauri
Length = 325
Score = 64.9 bits (151), Expect = 6e-10
Identities = 41/118 (34%), Positives = 55/118 (46%), Gaps = 5/118 (4%)
Frame = +1
Query: 67 VAHAKKGSL-----LIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFM 231
VAHA K L +D ST+D + I + G F +APVSG A++ L F+
Sbjct: 115 VAHAAKEGLSSGKGYVDVSTVDAGTSRAIAEVVRSTGAEFLEAPVSGSKKPAEDGALIFL 174
Query: 232 AGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIK 405
G + + R L VMG F G +G G KL NM+MG A AE + + K
Sbjct: 175 CAGDEGLYTRCTDPLDVMGKAHFFLGDVGQGAKMKLVVNMIMGSMMGAFAEGLTLADK 232
>UniRef50_A5P600 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Methylobacterium sp. 4-46|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Methylobacterium sp. 4-46
Length = 290
Score = 64.5 bits (150), Expect = 8e-10
Identities = 43/140 (30%), Positives = 67/140 (47%), Gaps = 3/140 (2%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
VVV+ L + + V LG +G++A +L+++ST+ P + A G+ + A
Sbjct: 55 VVVTSLPDDAALAAVALGPEGLLARMAPDGVLVETSTVSPETSAALREAAEAGGILYLAA 114
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVA---KLTNNM 351
PVSG A+ ATL G + ER+ PLL A+ H +G G+ A KL N
Sbjct: 115 PVSGSTATAEAATLTLFCSGPETALERARPLLATF-ARTIHA--VGPGEEARFLKLAINH 171
Query: 352 LMGITGMATAECMNMGIKMG 411
+G T AE + + + G
Sbjct: 172 FVGSTAQVAAEALTLARRGG 191
>UniRef50_Q9HLR4 Cluster: Putative uncharacterized protein Ta0161;
n=2; Thermoplasma|Rep: Putative uncharacterized protein
Ta0161 - Thermoplasma acidophilum
Length = 290
Score = 64.5 bits (150), Expect = 8e-10
Identities = 41/137 (29%), Positives = 65/137 (47%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
++V++L ++ V +VY + V +G + ID STI P+ +I EKG DA
Sbjct: 67 IIVTMLYDDRSVKEVYSQMEQGV----QGKVFIDMSTISPDTSIEIAKRIKEKGGKMYDA 122
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PV G + + L + GG ++ L+ + + G GSG AKL NN+ +G
Sbjct: 123 PVIGTSIAVEKKALVVLVGGDLSGYDEVRDLISATANQVVYMGDNGSGLYAKLVNNLFLG 182
Query: 361 ITGMATAECMNMGIKMG 411
+ AE + G K G
Sbjct: 183 SYMASLAEAVRFGRKNG 199
>UniRef50_A0YMN9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3;
Cyanobacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Lyngbya sp. PCC 8106
Length = 371
Score = 64.1 bits (149), Expect = 1e-09
Identities = 38/140 (27%), Positives = 65/140 (46%), Gaps = 3/140 (2%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
+ ++ T + + V G+ + + GS+ ID +T P ++ G+ D
Sbjct: 76 IFTALPTPSDTIKAVLEGEQNLSQGLRSGSIYIDITTNSPETIHRLHQAISPLGVEMLDV 135
Query: 181 PV---SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNM 351
P S G LA +A G + FER PLL++M + +CG+IGSG KL +N
Sbjct: 136 PFNDCSEGATSEGGMGLAVLASGSRATFERVEPLLQLMADQVLYCGEIGSGTRCKLIHNA 195
Query: 352 LMGITGMATAECMNMGIKMG 411
+ + A +E + +G+ G
Sbjct: 196 VNAVAVQAVSEGITLGLAQG 215
>UniRef50_A0RU56 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Cenarchaeum symbiosum|Rep: 3-hydroxyisobutyrate
dehydrogenase - Cenarchaeum symbiosum
Length = 282
Score = 64.1 bits (149), Expect = 1e-09
Identities = 37/127 (29%), Positives = 59/127 (46%)
Frame = +1
Query: 4 VVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 183
V++ +T + V G++G+ A K +L D STI+P I + G+ DAP
Sbjct: 51 VITCVTDADALEQVSFGENGIAQGAHKDLVLCDMSTINPEGAVSISKKLADAGIRMVDAP 110
Query: 184 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGI 363
V GG A L MA G K +E +L + K F+ G G+ KL N+ + +
Sbjct: 111 VMGGPGAAMRGELVIMASGDKGAYEERRGILGAVSRKMFYLGGSGTAYSIKLAMNLQIAM 170
Query: 364 TGMATAE 384
++ +E
Sbjct: 171 LAISLSE 177
>UniRef50_P71825 Cluster: Uncharacterized oxidoreductase
Rv0770/MT0794; n=18; Corynebacterineae|Rep:
Uncharacterized oxidoreductase Rv0770/MT0794 -
Mycobacterium tuberculosis
Length = 295
Score = 64.1 bits (149), Expect = 1e-09
Identities = 39/126 (30%), Positives = 54/126 (42%)
Frame = +1
Query: 34 VLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQN 213
V V +G+ HAK G+++ STI + +G+ DAPVSGG A
Sbjct: 76 VSSVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIHIVDAPVSGGAAAAAK 135
Query: 214 ATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMN 393
LA M G E F+R + H G+ G+G KL NML ++ A AE
Sbjct: 136 GELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARNMLTFVSYAAAAEAQR 195
Query: 394 MGIKMG 411
+ G
Sbjct: 196 LAEACG 201
>UniRef50_Q8PK98 Cluster: 3-hydroxyisobutirate dehydrogenase; n=3;
Proteobacteria|Rep: 3-hydroxyisobutirate dehydrogenase -
Xanthomonas axonopodis pv. citri
Length = 300
Score = 63.7 bits (148), Expect = 1e-09
Identities = 43/140 (30%), Positives = 60/140 (42%), Gaps = 3/140 (2%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVY--LGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFT 174
V+ L VVL+V L + L++D ST ++ + + F
Sbjct: 59 VIALSLPLPSVVLEVARTLAAAAAATEMRDSLLVVDLSTTGAQTTSEVGHLLERADVSFL 118
Query: 175 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHC-GQIGSGQVAKLTNNM 351
APVSGG A L MA G +ER+ PLL +G F+ G + GQ KL NN
Sbjct: 119 SAPVSGGTAAAAQGVLTVMAAGPLAAYERARPLLDAVGRHIFYLGGDVRLGQTLKLINNT 178
Query: 352 LMGITGMATAECMNMGIKMG 411
L +A+ E + G K G
Sbjct: 179 LYASAMLASCEALVCGAKAG 198
>UniRef50_Q3WJ00 Cluster: 6-phosphogluconate dehydrogenase, NAD
binding domain; n=1; Frankia sp. EAN1pec|Rep:
6-phosphogluconate dehydrogenase, NAD binding domain -
Frankia sp. EAN1pec
Length = 438
Score = 63.7 bits (148), Expect = 1e-09
Identities = 39/126 (30%), Positives = 55/126 (43%)
Frame = +1
Query: 34 VLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQN 213
V +V G DG+ G++++ ST+ P ++I A GL DAPVSGG A
Sbjct: 239 VEEVMFGPDGLAGTLNPGAVVLVHSTVAPAQIRRIAGRAATHGLRVLDAPVSGGQPRALA 298
Query: 214 ATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMN 393
L M GG + LL + H G +G+G AKL NN + + M
Sbjct: 299 GELTIMIGGDADTLADVAELLSALSNHVVHLGAVGAGSYAKLINNTMFAAQIALADDAMK 358
Query: 394 MGIKMG 411
G +G
Sbjct: 359 AGESLG 364
>UniRef50_UPI00015B4162 Cluster: PREDICTED: similar to MGC108315
protein; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to MGC108315 protein - Nasonia vitripennis
Length = 276
Score = 63.3 bits (147), Expect = 2e-09
Identities = 27/50 (54%), Positives = 39/50 (78%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIA 150
V+V++L N+ VLD Y GKDG+++ AKKG+ L+DSSTIDP+V + +F A
Sbjct: 83 VIVTMLPMNQHVLDTYTGKDGIISSAKKGTFLVDSSTIDPSVSQTVFKAA 132
Score = 47.6 bits (108), Expect = 1e-04
Identities = 19/40 (47%), Positives = 28/40 (70%)
Frame = +1
Query: 292 KQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMG 411
K HCG G GQVAK+ NNML+ I+ + +E +++G K+G
Sbjct: 134 KAVHCGDTGMGQVAKICNNMLLAISMIGVSEALSLGEKLG 173
>UniRef50_Q5LNV6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Rhodobacteraceae|Rep: 3-hydroxyisobutyrate dehydrogenase
- Silicibacter pomeroyi
Length = 269
Score = 63.3 bits (147), Expect = 2e-09
Identities = 35/99 (35%), Positives = 50/99 (50%)
Frame = +1
Query: 58 DGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAG 237
D + HAK +I ST+ P + + + + DAP+SG + AQ A L+FM G
Sbjct: 74 DQKLIHAKHLDCVIICSTLSPRYVRDL-RARVPDHIALIDAPMSGAQIAAQEARLSFMLG 132
Query: 238 GRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNML 354
G D + + PL MG+ G GSG AK+ NN+L
Sbjct: 133 GEPADLDAAQPLFAAMGSHFHRMGPYGSGMQAKVLNNLL 171
>UniRef50_Q9RX16 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=6;
Bacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Deinococcus radiodurans
Length = 310
Score = 62.9 bits (146), Expect = 3e-09
Identities = 34/104 (32%), Positives = 53/104 (50%)
Frame = +1
Query: 73 HAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKED 252
H + G++ +D ++ P+ ++ G+ F DAPVSGG GA+ TL M GG ++
Sbjct: 100 HLRPGTVWVDCTSGHPDAARRQRETLDALGVKFLDAPVSGGTSGAEAGTLTVMLGGPADE 159
Query: 253 FERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAE 384
+ + P L G K G+ G+G K NNML+ + A E
Sbjct: 160 IDAASPHLAFAG-KVVRVGETGAGFAVKAVNNMLLAVNLWAAGE 202
>UniRef50_A7H7Z5 Cluster: 6-phosphogluconate dehydrogenase
NAD-binding; n=2; Anaeromyxobacter|Rep:
6-phosphogluconate dehydrogenase NAD-binding -
Anaeromyxobacter sp. Fw109-5
Length = 293
Score = 62.5 bits (145), Expect = 3e-09
Identities = 39/129 (30%), Positives = 59/129 (45%), Gaps = 2/129 (1%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
+V++ ++ K + V G DGV+ + G +L+D ST + + A +G GF
Sbjct: 61 LVITCVSDEKALDTVLEGPDGVLEALRDGDVLVDMSTAGVRAARSVSERAAARGAGFVAC 120
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PV G A+ A L +AGG ER+ P L + A+ F + KL N + G
Sbjct: 121 PVLGSRSAAEQAQLVLVAGGPAVARERARPALHAVSARIFELEDAAQAALMKLCVNAIGG 180
Query: 361 --ITGMATA 381
ITG A
Sbjct: 181 AMITGFGEA 189
>UniRef50_Q49A26 Cluster: Cytokine-like nuclear factor n-pac; n=46;
Euteleostomi|Rep: Cytokine-like nuclear factor n-pac -
Homo sapiens (Human)
Length = 553
Score = 62.5 bits (145), Expect = 3e-09
Identities = 34/126 (26%), Positives = 61/126 (48%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
+ + ++ K D+ LG GV+ + G +D ST+D + ++ + + +G F +A
Sbjct: 326 ITFACVSDPKAAKDLVLGPSGVLQGIRPGKCYVDMSTVDADTVTELAQVIVSRGGRFLEA 385
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSG + + L +A G + +E + MG F G++G+ L NM+ G
Sbjct: 386 PVSGNQQLSNDGMLVILAAGDRGLYEDCSSCFQTMGKTSFFLGEVGNAAKMMLIVNMVQG 445
Query: 361 ITGMAT 378
+ MAT
Sbjct: 446 -SFMAT 450
>UniRef50_Q20XN2 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Rhodopseudomonas palustris BisB18|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Rhodopseudomonas palustris (strain BisB18)
Length = 365
Score = 62.1 bits (144), Expect = 4e-09
Identities = 43/138 (31%), Positives = 67/138 (48%), Gaps = 1/138 (0%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
VV S L ++ V V G G+V K G++ I STI P + +++ E G G+ A
Sbjct: 78 VVFSSLPDDEAVTAVAAGAGGLVKIMKAGAVHISMSTISPTMSRRLAAWHGECGQGYVAA 137
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQ-IGSGQVAKLTNNMLM 357
PV G A+ TL +A G +++ PLL +G K F G+ + + KL N+L
Sbjct: 138 PVLGNPDLARARTLFILAAGPDAAMQKARPLLDRLGQKLFVIGEDAAAANLVKLAGNVLT 197
Query: 358 GITGMATAECMNMGIKMG 411
+T + E + + K G
Sbjct: 198 ALTLQSMGEVLALLRKSG 215
>UniRef50_A6VYD9 Cluster: 2-hydroxy-3-oxopropionate reductase
precursor; n=5; Gammaproteobacteria|Rep:
2-hydroxy-3-oxopropionate reductase precursor -
Marinomonas sp. MWYL1
Length = 300
Score = 62.1 bits (144), Expect = 4e-09
Identities = 42/134 (31%), Positives = 63/134 (47%), Gaps = 1/134 (0%)
Frame = +1
Query: 7 VSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 186
V +L N ++ L G+ A K + ++ S+TI K I + L DAPV
Sbjct: 66 VLVLVVNAKQVNSVLFDSGLAAALKPQTAVMVSATISAEDAKAIHQKLSQYQLLMLDAPV 125
Query: 187 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCG-QIGSGQVAKLTNNMLMGI 363
SGG A + MA G E FE+ P+L AK ++ G +IG G K+ + +L G+
Sbjct: 126 SGGAAKAATGDMTVMASGSVEAFEKLQPVLDATAAKVYNIGEEIGLGATVKIIHQLLAGV 185
Query: 364 TGMATAECMNMGIK 405
A AE M + +
Sbjct: 186 HIAAGAEAMALAAR 199
>UniRef50_Q9LM23 Cluster: Fructose-bisphosphate aldolase; n=2;
Arabidopsis thaliana|Rep: Fructose-bisphosphate aldolase
- Arabidopsis thaliana (Mouse-ear cress)
Length = 1486
Score = 62.1 bits (144), Expect = 4e-09
Identities = 43/140 (30%), Positives = 66/140 (47%), Gaps = 3/140 (2%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKG--LGFT 174
V+V ++T+ DV G G V G+ ++ +ST+ P Q+ +G L
Sbjct: 413 VLVIMVTNEVQAEDVLYGHLGAVEAIPSGATVVLASTVSPAFVSQLERRLENEGKDLKLV 472
Query: 175 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHC-GQIGSGQVAKLTNNM 351
DAPVSGGV A L MA G E + + +L + K + G G+G K+ N +
Sbjct: 473 DAPVSGGVKRAAMGELTIMASGTDEALKSAGLVLSALSEKLYVIKGGCGAGSGVKMVNQL 532
Query: 352 LMGITGMATAECMNMGIKMG 411
L G+ + AE M G ++G
Sbjct: 533 LAGVHIASAAEAMAFGARLG 552
Score = 42.7 bits (96), Expect = 0.003
Identities = 25/80 (31%), Positives = 40/80 (50%), Gaps = 1/80 (1%)
Frame = +1
Query: 175 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHC-GQIGSGQVAKLTNNM 351
DA V G+ + L +A GR + R+ P L M + G+IG+G K+ N +
Sbjct: 145 DAYVLKGMSELLDGKLMIIASGRSDSITRAQPYLTAMCQNLYTFEGEIGAGSKVKMVNEL 204
Query: 352 LMGITGMATAECMNMGIKMG 411
L GI +A E +++G + G
Sbjct: 205 LEGIHLVAAVEAISLGSQAG 224
>UniRef50_Q8VYC5 Cluster: Fructose-bisphosphate aldolase; n=12;
cellular organisms|Rep: Fructose-bisphosphate aldolase -
Arabidopsis thaliana (Mouse-ear cress)
Length = 1373
Score = 62.1 bits (144), Expect = 4e-09
Identities = 43/140 (30%), Positives = 66/140 (47%), Gaps = 3/140 (2%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKG--LGFT 174
V+V ++T+ DV G G V G+ ++ +ST+ P Q+ +G L
Sbjct: 380 VLVIMVTNEVQAEDVLYGHLGAVEAIPSGATVVLASTVSPAFVSQLERRLENEGKDLKLV 439
Query: 175 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHC-GQIGSGQVAKLTNNM 351
DAPVSGGV A L MA G E + + +L + K + G G+G K+ N +
Sbjct: 440 DAPVSGGVKRAAMGELTIMASGTDEALKSAGLVLSALSEKLYVIKGGCGAGSGVKMVNQL 499
Query: 352 LMGITGMATAECMNMGIKMG 411
L G+ + AE M G ++G
Sbjct: 500 LAGVHIASAAEAMAFGARLG 519
Score = 57.6 bits (133), Expect = 9e-08
Identities = 41/139 (29%), Positives = 69/139 (49%), Gaps = 3/139 (2%)
Frame = +1
Query: 4 VVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKG--LGFTD 177
VV +L+ + DV G +GV+ +K ++L+ SSTI +++ EK + D
Sbjct: 62 VVVVLSHPDQIQDVIFGDEGVMKGLQKDAVLLLSSTISTLQLQKLEKQLTEKREQIFVVD 121
Query: 178 APVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHC-GQIGSGQVAKLTNNML 354
A V G+ + L +A GR + R+ P L M + G+IG+G K+ N +L
Sbjct: 122 AYVLKGMSELLDGKLMIIASGRSDSITRAQPYLTAMCQNLYTFEGEIGAGSKVKMVNELL 181
Query: 355 MGITGMATAECMNMGIKMG 411
GI +A E +++G + G
Sbjct: 182 EGIHLVAAVEAISLGSQAG 200
>UniRef50_Q8U2W2 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=17;
Pyrococcus|Rep: 3-hydroxyisobutyrate dehydrogenase -
Pyrococcus furiosus
Length = 278
Score = 62.1 bits (144), Expect = 4e-09
Identities = 32/110 (29%), Positives = 55/110 (50%)
Frame = +1
Query: 82 KGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFER 261
+G +++D++T + I G + ++PV G V+ A+N L + G +E FER
Sbjct: 77 RGKIIVDTTTNHHEKVLEFHEIYRNVGAFYLESPVIGSVIPARNGQLTILVSGEREAFER 136
Query: 262 SLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMG 411
P L+ +G + F+ + G KL NN ++G A E + +G K G
Sbjct: 137 VRPYLQKLGKRIFYFNEPGKATKLKLINNFVLGAFMAALGEAIALGEKAG 186
>UniRef50_Q0RIL5 Cluster: Putative uncharacterized protein; n=1;
Frankia alni ACN14a|Rep: Putative uncharacterized
protein - Frankia alni (strain ACN14a)
Length = 493
Score = 61.7 bits (143), Expect = 6e-09
Identities = 34/118 (28%), Positives = 66/118 (55%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
V+V+++T+++ DV G++G++A A G ++ ST++ V ++ + E +GF D
Sbjct: 66 VMVAVVTADQA-RDVIGGENGLLAGAHPGLTIVLLSTVELAVVHELAALCAEHDVGFLDC 124
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNML 354
V+ G A + +A + GG + E + P+L + HCG +G+G V K+ N++
Sbjct: 125 GVTPGDRAADHGMVA-IVGGDEATVEAARPVLDDWARRVVHCGPLGAGMVTKIARNVV 181
>UniRef50_UPI0000D55E08 Cluster: PREDICTED: similar to CG4747-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG4747-PA - Tribolium castaneum
Length = 267
Score = 61.3 bits (142), Expect = 8e-09
Identities = 41/142 (28%), Positives = 66/142 (46%), Gaps = 5/142 (3%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLL-----IDSSTIDPNVPKQIFPIALEKGL 165
VV S L + +V +G GV+ A+ + L ++ ++IDP+ K I I KG
Sbjct: 34 VVFSCLADPRSAKEVVIGNCGVIHQAEGPAALAGKGYVEMTSIDPDTSKDICNIIESKGG 93
Query: 166 GFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTN 345
+ +A + G A++ +L +A G K F+ K +G F+ G +GS L
Sbjct: 94 RYLEAQMQGSKKQAEDGSLIILAAGDKSLFDDCQTCFKAIGKTAFYLGTVGSATKMNLCI 153
Query: 346 NMLMGITGMATAECMNMGIKMG 411
NM +GI AE M + + G
Sbjct: 154 NMALGIGLAGLAESMVLAERCG 175
>UniRef50_A4ECY9 Cluster: Putative uncharacterized protein; n=1;
Collinsella aerofaciens ATCC 25986|Rep: Putative
uncharacterized protein - Collinsella aerofaciens ATCC
25986
Length = 359
Score = 61.3 bits (142), Expect = 8e-09
Identities = 41/129 (31%), Positives = 60/129 (46%), Gaps = 2/129 (1%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
VV +++ V ++YL DG++ K G++LID +T P + + I A G D
Sbjct: 63 VVFTMVGYPSEVEELYLAGDGLLTCTKPGAVLIDLTTSSPELARDIAEAAQVSGRMAFDC 122
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PV+GG GA TL + G + D +L A G GQ AKL N + +
Sbjct: 123 PVTGGESGAIAGTLTAIVGATENDIAPVRDVLSTFAANICCFDGAGKGQAAKLANQVSLA 182
Query: 361 --ITGMATA 381
+ GMA A
Sbjct: 183 ACMVGMADA 191
>UniRef50_A1UJF3 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=4; Actinomycetales|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Mycobacterium sp. (strain KMS)
Length = 272
Score = 61.3 bits (142), Expect = 8e-09
Identities = 39/137 (28%), Positives = 62/137 (45%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
VVV + T ++V G G++A G+ L+ +T P+ + + + G+ DA
Sbjct: 61 VVVCVFTDDQVRAVCLDG--GLLAAMAPGATLVIHTTGSPDTARLLAARGRDHGVDVVDA 118
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSGG + GG + ER+ P+L G H G +G+GQ KL NN +
Sbjct: 119 PVSGGPHDIAAGAVTLFVGGSEAAVERARPVLAAYGDPILHVGPLGAGQSVKLVNNTVFA 178
Query: 361 ITGMATAECMNMGIKMG 411
E + +G +G
Sbjct: 179 AQIGLLREAVRLGGALG 195
>UniRef50_A0R1N5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Mycobacterium|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Mycobacterium smegmatis
(strain ATCC 700084 / mc(2)155)
Length = 263
Score = 61.3 bits (142), Expect = 8e-09
Identities = 40/137 (29%), Positives = 62/137 (45%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
V+V + T +V L D ++ G++L+ +T P + I A ++G+ DA
Sbjct: 60 VIVCVFTDEQVRT---LCTDTLLDAMAPGAVLVLHTTGSPRTAEDIAARAADRGVAVVDA 116
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSGG ++ AGG + ER P L H G +GSGQ KL NN +
Sbjct: 117 PVSGGPHDIAAGSVTVFAGGDADVVERVRPALVAYAEPLLHVGPLGSGQRVKLVNNTMFA 176
Query: 361 ITGMATAECMNMGIKMG 411
AE + + ++G
Sbjct: 177 AQIGVVAEGVRLARELG 193
>UniRef50_Q89RT2 Cluster: Bll2680 protein; n=1; Bradyrhizobium
japonicum|Rep: Bll2680 protein - Bradyrhizobium
japonicum
Length = 300
Score = 60.9 bits (141), Expect = 1e-08
Identities = 34/136 (25%), Positives = 62/136 (45%)
Frame = +1
Query: 4 VVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 183
V++ L + + LG GV+A G++LI++ST+ ++ A +G+ + AP
Sbjct: 65 VITSLPDDTALRGALLGPAGVIAAMAPGAVLIETSTVSVEASTEVAASAQARGVLYLRAP 124
Query: 184 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGI 363
VSG L G K+ F+ + PL + + G + AKL N+++ +
Sbjct: 125 VSGNASIVHTGALTCFVSGPKDAFDNAKPLFAAFTRARTYLGPAEEARYAKLAVNLMIAV 184
Query: 364 TGMATAECMNMGIKMG 411
+ AE + + K G
Sbjct: 185 SAAMMAESLALARKGG 200
>UniRef50_Q4WV01 Cluster: Oxidoreductase, acting on the CH-OH group
of donors, NAD or NADP as acceptor; n=7;
Pezizomycotina|Rep: Oxidoreductase, acting on the CH-OH
group of donors, NAD or NADP as acceptor - Aspergillus
fumigatus (Sartorya fumigata)
Length = 435
Score = 60.5 bits (140), Expect = 1e-08
Identities = 40/141 (28%), Positives = 65/141 (46%), Gaps = 6/141 (4%)
Frame = +1
Query: 7 VSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKG---LGFTD 177
+ ++ S V V G DGVV K + L ST+ + + + +G + F D
Sbjct: 64 ICMVASAPQVQSVLFGDDGVVQFLPKNATLFLCSTVPASYAQSVAAELQSRGRADIRFID 123
Query: 178 APVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQ---FHCGQIGSGQVAKLTNN 348
PVSGG A + TL+ MAG +E +L+VM + G +G+G K+ +
Sbjct: 124 CPVSGGAKRAADGTLSIMAGASEEALNSGREILQVMSDQNKLYLVPGGVGAGSNMKMVHQ 183
Query: 349 MLMGITGMATAECMNMGIKMG 411
+L GI + +E M ++G
Sbjct: 184 VLAGIHILGASEAMGFAAQLG 204
>UniRef50_A0JRK4 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=3; Actinomycetales|Rep:
6-phosphogluconate dehydrogenase, NAD-binding precursor
- Arthrobacter sp. (strain FB24)
Length = 299
Score = 60.1 bits (139), Expect = 2e-08
Identities = 39/126 (30%), Positives = 64/126 (50%), Gaps = 2/126 (1%)
Frame = +1
Query: 40 DVYLGKDGVVAHAKKGSLLIDSSTIDPN-VPKQIFPIALEKGLGFTDAPVSGGVMGAQNA 216
DV G +GV + K G+++I ST+ + +P + +A E G+ DAP+SGG A
Sbjct: 75 DVLFGANGVASVLKPGAVVILGSTVGTDAIPATVDRLA-EYGVELVDAPLSGGPKRAGEG 133
Query: 217 TLAFMAGGRKEDFERSLPLLKVMGAKQFHCG-QIGSGQVAKLTNNMLMGITGMATAECMN 393
L + G E E++ P L+++ + G + G GQ K N +L G+ A AE +
Sbjct: 134 DLLIVVGASPEAQEKARPALELLASTLTVVGDKPGDGQALKTVNQLLCGVHIAAAAEALA 193
Query: 394 MGIKMG 411
+ +G
Sbjct: 194 LADALG 199
>UniRef50_Q221W9 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
Rhodoferax ferrireducens T118|Rep:
2-hydroxy-3-oxopropionate reductase - Rhodoferax
ferrireducens (strain DSM 15236 / ATCC BAA-621 / T118)
Length = 303
Score = 59.7 bits (138), Expect = 2e-08
Identities = 34/137 (24%), Positives = 60/137 (43%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
V++ +T + V +V G G++ K G +++D ST P+ +++ KG F DA
Sbjct: 70 VIIICVTGSPQVEEVVFGDTGILQTLKPGCVVVDCSTSLPDSTRRVAQAIAAKGGQFLDA 129
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
++G A L + GG E P+ + F+CG + +G KL + ++
Sbjct: 130 AMTGTPKHADEGKLNLLVGGDPEVLTSVRPVFALFAENIFYCGAVSAGHTTKLLHQFVVL 189
Query: 361 ITGMATAECMNMGIKMG 411
AE + K G
Sbjct: 190 GNAAILAEAFSCASKTG 206
>UniRef50_Q97ZE5 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=4;
Sulfolobaceae|Rep: 3-hydroxyisobutyrate dehydrogenase -
Sulfolobus solfataricus
Length = 289
Score = 59.7 bits (138), Expect = 2e-08
Identities = 36/110 (32%), Positives = 51/110 (46%)
Frame = +1
Query: 82 KGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFER 261
KG +LID STI P + + G DAPV G + + L + GG K+ F+
Sbjct: 83 KGKILIDMSTISPTLSISLAKRIESNGGTMFDAPVIGTSVFVEQKKLVVLVGGPKDKFDI 142
Query: 262 SLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMG 411
+ K + + G G G +KL NN+L+ A AE N GI+ G
Sbjct: 143 VNDIAKETASLVVYMGPNGMGLYSKLVNNLLLASYVAAIAEAYNFGIRAG 192
>UniRef50_Q98K09 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=7;
Alphaproteobacteria|Rep: 3-hydroxyisobutyrate
dehydrogenase - Rhizobium loti (Mesorhizobium loti)
Length = 312
Score = 59.3 bits (137), Expect = 3e-08
Identities = 38/137 (27%), Positives = 60/137 (43%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
+V +T ++ V + G G+ KKGS+++D ST DP + G+ + DA
Sbjct: 67 IVFICVTGSREVEAIIRGPGGLKEGLKKGSVVVDCSTSDPVSTVALAAELKALGIDYVDA 126
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
P+S A TL M G F R P+++ + H G G G KL NN +
Sbjct: 127 PLSRTPKEAWEGTLDAMVGAPDAVFARVKPVIETWAGRIVHIGDTGDGHRMKLLNNFISL 186
Query: 361 ITGMATAECMNMGIKMG 411
+E + + K+G
Sbjct: 187 GYAAIYSEALALAEKVG 203
>UniRef50_A1CAY2 Cluster: Oxidoreductase, acting on the CH-OH group
of donors, NAD or NADP as acceptor; n=2;
Aspergillus|Rep: Oxidoreductase, acting on the CH-OH
group of donors, NAD or NADP as acceptor - Aspergillus
clavatus
Length = 436
Score = 59.3 bits (137), Expect = 3e-08
Identities = 41/141 (29%), Positives = 66/141 (46%), Gaps = 6/141 (4%)
Frame = +1
Query: 7 VSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKG---LGFTD 177
V ++ S V V G DG+V + + L ST+ + + + G + F D
Sbjct: 64 VCMVASAPQVQSVLFGDDGIVQYLPPNATLFLCSTVPASYAQSVAAELQSLGRADIRFID 123
Query: 178 APVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMG-AKQFHC--GQIGSGQVAKLTNN 348
PVSGG A + TL+ MAG +E +L+VM K+ + G IG+G K+ +
Sbjct: 124 CPVSGGAKRAADGTLSIMAGAPEEALNSGREILQVMSDQKKLYLVPGGIGAGSNMKMVHQ 183
Query: 349 MLMGITGMATAECMNMGIKMG 411
+L GI + +E M ++G
Sbjct: 184 VLAGIHILGASEAMGFAAQLG 204
>UniRef50_A3ET09 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3;
Bacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Leptospirillum sp. Group II UBA
Length = 311
Score = 58.4 bits (135), Expect = 5e-08
Identities = 31/137 (22%), Positives = 67/137 (48%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
V+++++ +++ + ++ + G + ++ +T+ P++ ++ + ++G +A
Sbjct: 69 VIITVVGTDREMDALFAETGDSLLVGASGRVFVNCATLSPDIHVEVERRSNDRGADCLEA 128
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
++ + A+ TL M GG+KE FER P+L+ M A G G K NM+M
Sbjct: 129 SMASSITQAREGTLYLMVGGKKEAFERVRPVLEAMSASLRWIGPAGQAAKIKALVNMVMN 188
Query: 361 ITGMATAECMNMGIKMG 411
I AE + + +G
Sbjct: 189 INTAGLAEGLGLADALG 205
>UniRef50_Q7WNK6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Bordetella bronchiseptica|Rep: 3-hydroxyisobutyrate
dehydrogenase - Bordetella bronchiseptica (Alcaligenes
bronchisepticus)
Length = 306
Score = 58.0 bits (134), Expect = 7e-08
Identities = 35/124 (28%), Positives = 55/124 (44%), Gaps = 1/124 (0%)
Frame = +1
Query: 43 VYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATL 222
V G+ G A G+ + +ST+ P + + E G G D PVSGG GAQ L
Sbjct: 79 VLFGEGGAAAALPAGATVWLASTVAPAYARGLQARLREHGAGLVDGPVSGGATGAQAGAL 138
Query: 223 AFMAGGRKEDFERSLPLLKVMGAKQFHCG-QIGSGQVAKLTNNMLMGITGMATAECMNMG 399
+A G+ + + P ++ + G + G+ KL N +L TAE + +G
Sbjct: 139 TIIASGQAQALAAAEPAMRACSSIIHRVGEEAGAASTVKLVNQLLTASHIALTAEALALG 198
Query: 400 IKMG 411
+ G
Sbjct: 199 ARAG 202
>UniRef50_Q6F842 Cluster: Putative 3-hydroxyisobutyrate
dehydrogenase or 2-hydroxy-3- oxopropionate reductase;
n=2; Acinetobacter|Rep: Putative 3-hydroxyisobutyrate
dehydrogenase or 2-hydroxy-3- oxopropionate reductase -
Acinetobacter sp. (strain ADP1)
Length = 291
Score = 58.0 bits (134), Expect = 7e-08
Identities = 34/137 (24%), Positives = 64/137 (46%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
V++ L ++ V VY + V + +++D S++ N K + A ++ + D+
Sbjct: 63 VILMCLADDQAVNHVY---EQVHHLVRPQQIIVDFSSLSVNQTKYLADRAQQQQAIWIDS 119
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSGG GA+ TL AGG + + + V+ + G G+GQ K+ N +++
Sbjct: 120 PVSGGTSGAEQGTLVIFAGGNESTIQDLGLIYNVLSQRVTRMGDTGTGQATKICNQLIVA 179
Query: 361 ITGMATAECMNMGIKMG 411
AE + + + G
Sbjct: 180 ANSALIAEAVALAHRAG 196
>UniRef50_Q1GF31 Cluster: 6-phosphogluconate dehydrogenase
NAD-binding; n=17; Proteobacteria|Rep:
6-phosphogluconate dehydrogenase NAD-binding -
Silicibacter sp. (strain TM1040)
Length = 325
Score = 58.0 bits (134), Expect = 7e-08
Identities = 29/86 (33%), Positives = 43/86 (50%)
Frame = +1
Query: 97 IDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLL 276
++ ST D K++ + E+G + PVSGG A ++ AG + FER LP L
Sbjct: 88 MEMSTTDAAEVKRLAALVSERGGSAMECPVSGGCHRADTGNISIFAGCDRATFERMLPTL 147
Query: 277 KVMGAKQFHCGQIGSGQVAKLTNNML 354
+G + H G IGS + K+ N L
Sbjct: 148 TTLGRRVLHTGDIGSASILKVMTNYL 173
>UniRef50_UPI0001597301 Cluster: YfjR; n=1; Bacillus
amyloliquefaciens FZB42|Rep: YfjR - Bacillus
amyloliquefaciens FZB42
Length = 286
Score = 57.6 bits (133), Expect = 9e-08
Identities = 39/138 (28%), Positives = 66/138 (47%), Gaps = 1/138 (0%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
+V+S+L+ + V DV G G++A + + I STI + +Q+ +G F A
Sbjct: 59 IVLSMLSDDDAVTDVTFGACGIIAGLSENGIHISMSTISTALSEQLSAAHSGRGQSFIAA 118
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCG-QIGSGQVAKLTNNMLM 357
PV G A+ A L + G E +++ PLL ++ + F G + + AK++ N L+
Sbjct: 119 PVLGRPDAAEKAELRIITAGPAEAKKKAEPLLNILSQQVFDTGEETKTANAAKISVNFLL 178
Query: 358 GITGMATAECMNMGIKMG 411
A +E M K G
Sbjct: 179 VSMLEALSESFLMMEKYG 196
>UniRef50_Q98I20 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Alphaproteobacteria|Rep: 3-hydroxyisobutyrate
dehydrogenase - Rhizobium loti (Mesorhizobium loti)
Length = 305
Score = 57.6 bits (133), Expect = 9e-08
Identities = 39/135 (28%), Positives = 64/135 (47%)
Frame = +1
Query: 7 VSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 186
++ L S K+ V G G++ KG I+ ST + ++ +A +G+ + PV
Sbjct: 63 ITCLPSPKISEAVLAGPGGLLEGLPKGGTWIEMSTNGRDEIMRLAALASAEGVETLECPV 122
Query: 187 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 366
+GGV A + + GG +ER ++ M A+ F G IGS V K+ NML I
Sbjct: 123 TGGVHLAAVGKITALVGGDAALYERHRAAIEAMCARSFLMGPIGSAAVIKVITNMLAFIH 182
Query: 367 GMATAECMNMGIKMG 411
+A E + + + G
Sbjct: 183 LVAAGEALMLAKQGG 197
>UniRef50_Q8F4I7 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=4;
Leptospira|Rep: 3-hydroxyisobutyrate dehydrogenase -
Leptospira interrogans
Length = 296
Score = 57.6 bits (133), Expect = 9e-08
Identities = 29/91 (31%), Positives = 48/91 (52%)
Frame = +1
Query: 82 KGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFER 261
K +LID T ++ ++ + EK + F D+P++G A++ + FM G ++ D +
Sbjct: 87 KPPILIDCGTTSLSLTLKLSKLCSEKKIRFYDSPMTGSKNAARDGQILFMIGAKQVDIKD 146
Query: 262 SLPLLKVMGAKQFHCGQIGSGQVAKLTNNML 354
+V G +CG IG GQ AKL NM+
Sbjct: 147 IQFFFEVCGKNAVYCGSIGGGQKAKLALNMI 177
>UniRef50_Q1B326 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding protein precursor; n=7; Bacteria|Rep:
6-phosphogluconate dehydrogenase, NAD-binding protein
precursor - Mycobacterium sp. (strain MCS)
Length = 299
Score = 57.6 bits (133), Expect = 9e-08
Identities = 39/138 (28%), Positives = 66/138 (47%), Gaps = 1/138 (0%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
VVV++L ++ V V G DG+VA + ++ + SSTI + +++ E G F A
Sbjct: 61 VVVTMLANDDAVEAVSFGDDGIVASLRPDAIHVSSSTISLALAERLTAAHAEGGSRFVSA 120
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCG-QIGSGQVAKLTNNMLM 357
PV G A A L +A G + E P+ + +G + F G + + + K++ N L+
Sbjct: 121 PVFGRPEAAAAAKLFVVAAGAPDTVEALAPVFEAIGQRTFVVGTEPKAANLVKVSGNFLI 180
Query: 358 GITGMATAECMNMGIKMG 411
+ E M + K G
Sbjct: 181 ASVIESLGEAMALVAKGG 198
>UniRef50_Q1V2K7 Cluster: NADP oxidoreductase, coenzyme
F420-dependent:6- phosphogluconatedehydrogenase,
NAD-binding:3-hydroxyacyl-CoA; n=1; Candidatus
Pelagibacter ubique HTCC1002|Rep: NADP oxidoreductase,
coenzyme F420-dependent:6-
phosphogluconatedehydrogenase,
NAD-binding:3-hydroxyacyl-CoA - Candidatus Pelagibacter
ubique HTCC1002
Length = 284
Score = 57.2 bits (132), Expect = 1e-07
Identities = 29/89 (32%), Positives = 48/89 (53%)
Frame = +1
Query: 88 SLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSL 267
+L+ID +T D N + I K + + + PV GG + A+ L + GG +E+F+++
Sbjct: 88 TLIIDITTHDQNGSIEANKIFKSKNINYIECPVMGGPVQAEEGVLGGIIGGSEENFKKAE 147
Query: 268 PLLKVMGAKQFHCGQIGSGQVAKLTNNML 354
LK F+ G++G G +KL NN L
Sbjct: 148 VFLKAFCKDYFYFGEVGMGTKSKLLNNFL 176
>UniRef50_Q7NEW9 Cluster: Glr3759 protein; n=3; Bacteria|Rep:
Glr3759 protein - Gloeobacter violaceus
Length = 290
Score = 56.8 bits (131), Expect = 2e-07
Identities = 33/108 (30%), Positives = 51/108 (47%)
Frame = +1
Query: 61 GVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGG 240
G +A ++ I+SST+ +++ +G DAPVSG A+ L F+ GG
Sbjct: 81 GALAGLPADAVAIESSTLSVAGVQELAEHFQARGKTLLDAPVSGSRPQAEAGQLIFLVGG 140
Query: 241 RKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAE 384
++ P+L MG H G +G+G KL N L+G+ A E
Sbjct: 141 DAGAVAKAGPILNAMGGTVHHAGPLGNGAAVKLAINALLGVQVAAMGE 188
>UniRef50_Q01PV6 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Solibacter usitatus Ellin6076|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Solibacter usitatus (strain Ellin6076)
Length = 267
Score = 56.8 bits (131), Expect = 2e-07
Identities = 28/102 (27%), Positives = 50/102 (49%)
Frame = +1
Query: 85 GSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERS 264
G ++D +T +P + + G+ + DA V G ++ MAGGR+E F+ +
Sbjct: 67 GITMVDCTTGEPESMAAMGEKLAKSGVDYLDATVLGSSKVVRSGAAVVMAGGRRESFDAA 126
Query: 265 LPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECM 390
PL + ++ F+ G G+G KL N+ +G+ AE +
Sbjct: 127 SPLFRTFASRAFYLGPFGAGARMKLVVNLALGLHRAVLAETL 168
>UniRef50_A1WEB7 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Verminephrobacter eiseniae EF01-2|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Verminephrobacter eiseniae (strain EF01-2)
Length = 293
Score = 56.8 bits (131), Expect = 2e-07
Identities = 43/139 (30%), Positives = 66/139 (47%), Gaps = 2/139 (1%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
VVV L S L V + + H +G+++I+SST++P G+ DA
Sbjct: 56 VVVLCLPSPASSLSVI---EQIAPHLPQGAVVIESSTVNPEHVHAGQKRLAPFGVDVVDA 112
Query: 181 PVSGGV--MGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNML 354
+ GV M A +ATLA GG+ + RS +L + ++Q H G +G+G AK+ NN +
Sbjct: 113 SILAGVEQMAAGSATLAL--GGKPDAIARSQGVLDAIASRQIHFGALGAGAAAKVINNAV 170
Query: 355 MGITGMATAECMNMGIKMG 411
+ AE M G
Sbjct: 171 AHAVMVVVAEAGAMATAAG 189
>UniRef50_A5WG80 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Moraxellaceae|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Psychrobacter sp. PRwf-1
Length = 309
Score = 56.4 bits (130), Expect = 2e-07
Identities = 38/132 (28%), Positives = 57/132 (43%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
V+ S L +++VV D+ + + H GS+ +D ++ P K G F DA
Sbjct: 73 VIFSCLPTSQVVDDLI---EQALPHLNDGSVWVDCTSGVPENAKASQAKLNAAGCEFLDA 129
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSG GA + TL M GG + + + H G G+G K NN L
Sbjct: 130 PVSGQTSGADSGTLTVMVGGSAKALAYAKSAIDCFAGLIVHVGDSGAGFAVKAVNNTLFA 189
Query: 361 ITGMATAECMNM 396
I A E +++
Sbjct: 190 INAWAAVEGLSV 201
>UniRef50_A4FKN9 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep:
2-hydroxy-3-oxopropionate reductase - Saccharopolyspora
erythraea (strain NRRL 23338)
Length = 297
Score = 56.4 bits (130), Expect = 2e-07
Identities = 39/129 (30%), Positives = 67/129 (51%), Gaps = 2/129 (1%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
VVVS+ + +V V DG++A + +++D+ST P + + +G DA
Sbjct: 68 VVVSLPSGPQVRAAVV---DGLLADGGE-FVVVDTSTCAPADARSLADDLHARGCAVVDA 123
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLM- 357
PVSGG A+ +L+ M GG + D + +++ + CG G+GQ+AK N +++
Sbjct: 124 PVSGGPTAARAGSLSVMVGGTEADVAAADEVIRAFAGRVVVCGGPGAGQIAKACNQLVVT 183
Query: 358 -GITGMATA 381
GI +A A
Sbjct: 184 AGIAVVAEA 192
>UniRef50_A1SQ87 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=4; Bacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Nocardioides sp. (strain
BAA-499 / JS614)
Length = 318
Score = 56.4 bits (130), Expect = 2e-07
Identities = 35/138 (25%), Positives = 71/138 (51%), Gaps = 1/138 (0%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAH-AKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTD 177
VV +++++ + V +G+ G++A A+ ++++D ST+ + E+G+ F
Sbjct: 68 VVFTMVSTPADLEQVLVGEGGLLADPARVPAVVVDCSTVSTESSAAMRAACSERGVAFLA 127
Query: 178 APVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLM 357
APVSG + L+ + G +E +ER LL +G + G+ ++AK+ +N+++
Sbjct: 128 APVSGNGKVVRAGGLSLVVSGPEETYERVAHLLDHLGKGATYVGEGELARLAKICHNVML 187
Query: 358 GITGMATAECMNMGIKMG 411
G+ AE + K G
Sbjct: 188 GVVTQCLAEITVLAEKGG 205
>UniRef50_Q74D68 Cluster: 3-hydroxyisobutyrate dehydrogenase family
protein; n=7; Desulfuromonadales|Rep:
3-hydroxyisobutyrate dehydrogenase family protein -
Geobacter sulfurreducens
Length = 288
Score = 56.0 bits (129), Expect = 3e-07
Identities = 38/124 (30%), Positives = 52/124 (41%)
Frame = +1
Query: 40 DVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNAT 219
D+Y G DG+ A G++L+D T ++ A + + F DAPV G A N
Sbjct: 75 DIY-GPDGIFAGIDPGTILVDMGTHSLTSTMEMADEAAKHRVMFLDAPVWGTKEHAANGL 133
Query: 220 LAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMG 399
L +AGG R L G H G IG K N++ A AE + G
Sbjct: 134 LTILAGGDPSLVGRCRELFSFFGLNIIHVGSIGDATRMKFVVNLVQAELMQALAESIVFG 193
Query: 400 IKMG 411
K+G
Sbjct: 194 EKLG 197
>UniRef50_Q0RMX6 Cluster: Putative reductase; n=1; Frankia alni
ACN14a|Rep: Putative reductase - Frankia alni (strain
ACN14a)
Length = 262
Score = 55.6 bits (128), Expect = 4e-07
Identities = 31/120 (25%), Positives = 52/120 (43%)
Frame = +1
Query: 52 GKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFM 231
G G++AHA GS+++ +T+ +++ A + + DAP+SG L +
Sbjct: 66 GPGGLLAHATPGSVVVQHATVATEAIRRLAADAAAQDVTVLDAPISGTSATILAGRLTVL 125
Query: 232 AGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMG 411
GG +R PLL + G +GS KL NN+ + +G K+G
Sbjct: 126 IGGAAAAADRVEPLLAAYASTIVRTGDVGSATTVKLINNLTFAAHVQTAVAAVQLGEKLG 185
>UniRef50_A3Y8R5 Cluster: Putative dehydrogenase; n=1; Marinomonas
sp. MED121|Rep: Putative dehydrogenase - Marinomonas sp.
MED121
Length = 297
Score = 55.6 bits (128), Expect = 4e-07
Identities = 36/135 (26%), Positives = 63/135 (46%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
V+ + L S+ V + G++G++ +A+ G+ ++ST + + +++ IA L DA
Sbjct: 63 VIFTSLPSSVQVNHIAFGEEGILENAQAGATWFETSTNELSEWEKVKAIA-PSHLSLIDA 121
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PV+GG GA TL + G ++ + +L G G+G V KL L
Sbjct: 122 PVTGGAEGAAAGTLTMLLGIDEQILTKFTSMLNAFTKNAIRMGPSGAGYVTKLAQLHLNY 181
Query: 361 ITGMATAECMNMGIK 405
+ E + MG K
Sbjct: 182 LVAQGIGEALMMGAK 196
>UniRef50_A7I8V1 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Candidatus Methanoregula boonei
6A8|Rep: 6-phosphogluconate dehydrogenase, NAD-binding -
Methanoregula boonei (strain 6A8)
Length = 288
Score = 55.2 bits (127), Expect = 5e-07
Identities = 35/137 (25%), Positives = 63/137 (45%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
VV+ L + V V G +G+++ G ++ID++T + A + G + +
Sbjct: 60 VVLINLFDSDAVESVLSGPEGLLSGPCTGKIIIDTTTNHFGRVSDFYAGARDHGATYLEC 119
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PV G V+ A L + G + +E PLL +G+ ++ G+ KL NN+++G
Sbjct: 120 PVLGSVVPASQGKLTVLVSGDEGTYEVVKPLLSRIGSTLYYLGEPALATKMKLINNLVLG 179
Query: 361 ITGMATAECMNMGIKMG 411
AE + +G G
Sbjct: 180 SFMATCAEAVALGEAAG 196
>UniRef50_Q1GM24 Cluster: 6-phosphogluconate dehydrogenase
NAD-binding; n=3; Rhodobacteraceae|Rep:
6-phosphogluconate dehydrogenase NAD-binding -
Silicibacter sp. (strain TM1040)
Length = 292
Score = 54.4 bits (125), Expect = 9e-07
Identities = 35/138 (25%), Positives = 60/138 (43%), Gaps = 4/138 (2%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
VV+ +T + V + G GV ++ ++++D ST P ++ I G + DA
Sbjct: 61 VVILCVTGSPQVEAIVAGDQGVATALRQNAVIVDCSTALPESTLRMAEIVRAAGGDYLDA 120
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNML-- 354
P++ A TL + GG + ER P+L H G + G KL +N +
Sbjct: 121 PMTRTARHAHEGTLNLLVGGATDTLERVRPVLSTFTEDVAHVGPLSHGHRLKLLHNYVSV 180
Query: 355 --MGITGMATAECMNMGI 402
M + A A+ + G+
Sbjct: 181 GFMTLLAEAAAQSADAGV 198
>UniRef50_Q55W03 Cluster: Putative uncharacterized protein; n=2;
Filobasidiella neoformans|Rep: Putative uncharacterized
protein - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 414
Score = 54.0 bits (124), Expect = 1e-06
Identities = 33/110 (30%), Positives = 57/110 (51%), Gaps = 6/110 (5%)
Frame = +1
Query: 88 SLLIDSSTIDPNVPKQIFPI---ALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFE 258
++L+D +T+DP V I + + + DAPVSGG + A+ L M G
Sbjct: 170 TMLVDQTTLDPTVSLSISSLIHDSTSRAALMIDAPVSGGTVAAERGELTIMFGSPAPIAT 229
Query: 259 R-SLPLLKVMGAK--QFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMG 399
R ++PLL++M + CG G+G K+ NN+++ +A +E + +G
Sbjct: 230 RLAMPLLQMMAREGGVIECGGSGTGVGVKVCNNLVLASNQIALSEGLALG 279
>UniRef50_Q89GM2 Cluster: Bll6323 protein; n=6; Proteobacteria|Rep:
Bll6323 protein - Bradyrhizobium japonicum
Length = 300
Score = 53.6 bits (123), Expect = 2e-06
Identities = 32/138 (23%), Positives = 63/138 (45%), Gaps = 4/138 (2%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
+++ +T + V V G G ++ +KG++++D ST P ++ G F DA
Sbjct: 67 IIILCVTGSPQVEAVLTGDAGALSRLRKGTIIVDCSTALPESTLRMAAAVRAAGGAFLDA 126
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNML-- 354
P++ A++ L + GG + DF+ + +L + G + G KL +N +
Sbjct: 127 PMTRTAKHAEDGALNLLVGGDETDFQNACAVLASFTERVERVGPVSFGHRLKLLHNYVSI 186
Query: 355 --MGITGMATAECMNMGI 402
M + A A+ + G+
Sbjct: 187 GFMALLSEAAAQAADAGV 204
>UniRef50_A7RG59 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 341
Score = 53.6 bits (123), Expect = 2e-06
Identities = 33/117 (28%), Positives = 58/117 (49%)
Frame = +1
Query: 61 GVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGG 240
G+++ K+GS+ ID +T D N ++ +A KG+ +AP++GG + GG
Sbjct: 104 GMLSMLKEGSVWIDHTTTDYNETIRLGELATSKGVHAVEAPLTGG-----QGLMTVFVGG 158
Query: 241 RKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMG 411
++ + PL+ A + G +G VAK+ +NML +A E + + K G
Sbjct: 159 EEKVVQDVKPLMDSYTATFLYFGPLGKATVAKVISNMLCAAHLVAAGEALMLAKKAG 215
>UniRef50_Q21ZN3 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Rhodoferax ferrireducens T118|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Rhodoferax ferrireducens (strain DSM 15236 / ATCC
BAA-621 / T118)
Length = 292
Score = 53.2 bits (122), Expect = 2e-06
Identities = 37/137 (27%), Positives = 58/137 (42%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
VV+ +T + V + G++ + G ++ID ST P+ I LE G F DA
Sbjct: 66 VVMLCVTGSPQVESLMNRDQGILQSIRPGQIVIDCSTSQPSSSAIINAALLEAGALFVDA 125
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
P+ A+ L M G + E P+L+ H G++ S Q KL NN +
Sbjct: 126 PLGRTPAEAEAGKLNVMVGATPQLLEHIRPVLQAFCENIIHVGEVISAQKLKLINNFAVV 185
Query: 361 ITGMATAECMNMGIKMG 411
T E + ++G
Sbjct: 186 GTAALLTEALRACDQVG 202
>UniRef50_Q120Q9 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=7; Burkholderiales|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 297
Score = 52.8 bits (121), Expect = 3e-06
Identities = 34/118 (28%), Positives = 54/118 (45%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
+++ +T V DV K G++ K G+++ID ST P+ +I + G F DA
Sbjct: 61 IIILCVTGTPEVEDVLYRKGGLLEGIKPGTIVIDCSTAIPSSTIRIAESVEKAGGRFLDA 120
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNML 354
P++ A L + GG FE P+L+ G +GSG KL +N +
Sbjct: 121 PMTRTPKEAAEGRLNLIVGGDPALFESCKPVLECYAENIVLAGPVGSGHRLKLLHNFV 178
>UniRef50_Q9I1R8 Cluster: Probable dehydrogenase; n=7; Pseudomonas
aeruginosa|Rep: Probable dehydrogenase - Pseudomonas
aeruginosa
Length = 291
Score = 52.4 bits (120), Expect = 4e-06
Identities = 36/138 (26%), Positives = 68/138 (49%), Gaps = 1/138 (0%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
VV+S+L ++ + V L G + A+ G + + ST+ + + + +GL F A
Sbjct: 58 VVISMLADDQAIRGVLLDS-GALERARPGLIHLSMSTLSLDCVEALDQAHQRQGLAFVAA 116
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVA-KLTNNMLM 357
PV G A+ L + GG +E E+ LL++MG K + G+ G +A K++ N ++
Sbjct: 117 PVFGRTDVAEAGKLNIVVGGPEEAIEQVKALLEIMGQKTWFFGKDPRGAMAVKISGNFMI 176
Query: 358 GITGMATAECMNMGIKMG 411
+ E + + ++G
Sbjct: 177 ASAIESMGESVALVKRLG 194
>UniRef50_A1UDJ6 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=7; Mycobacterium|Rep:
6-phosphogluconate dehydrogenase, NAD-binding precursor
- Mycobacterium sp. (strain KMS)
Length = 292
Score = 52.4 bits (120), Expect = 4e-06
Identities = 43/138 (31%), Positives = 62/138 (44%), Gaps = 1/138 (0%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKD-GVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTD 177
VV++ L VL+V LG + GV+A G+ L+D ST +P V I G F D
Sbjct: 60 VVLTFLPGPSQVLEVALGSERGVLAGLADGAALLDMSTCNPEVAAIIGQAYDAAGRRFVD 119
Query: 178 APVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLM 357
PVS A N T+ + GG +L + +CG G+G KL N +
Sbjct: 120 CPVS---RKAPNMTV--LVGGPSGVLGPDADVLAAVSRTLVYCGHRGAGYATKLLNQHIK 174
Query: 358 GITGMATAECMNMGIKMG 411
+A+AE + + MG
Sbjct: 175 YSWYLASAEALLIAEAMG 192
>UniRef50_A0VSV4 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=1; Dinoroseobacter shibae DFL
12|Rep: 6-phosphogluconate dehydrogenase, NAD-binding
precursor - Dinoroseobacter shibae DFL 12
Length = 289
Score = 52.4 bits (120), Expect = 4e-06
Identities = 31/118 (26%), Positives = 52/118 (44%)
Frame = +1
Query: 58 DGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAG 237
D ++ H + G + ID++T P + G F+DAPV+GG AQ+ L + G
Sbjct: 79 DTLLPHTRPGQIWIDTTTSRPETSATLAHRLDAAGAVFSDAPVTGGPKQAQDGALTSLVG 138
Query: 238 GRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMG 411
F+ L+ G G+G AKL NN++ T + ++ ++G
Sbjct: 139 CAAAQFDTIASLVGTYSTAIRRFGDAGTGHAAKLLNNLVTQGTMVLLSDAFQAAGRLG 196
>UniRef50_Q1NHF5 Cluster: Putative oxidoreductase; n=1; Sphingomonas
sp. SKA58|Rep: Putative oxidoreductase - Sphingomonas
sp. SKA58
Length = 283
Score = 52.0 bits (119), Expect = 5e-06
Identities = 31/119 (26%), Positives = 56/119 (47%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
VV+ + + K +DV G DGV++ A+ G +++ +T+ I + G+ D
Sbjct: 60 VVIIAVVNAKQTIDVLSGPDGVLSRARPGMIVVLVATVSIEDLDAIRALTDAAGVELVDC 119
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLM 357
V+GG ++ L + GG E + P+L H G G+G AK+ N+++
Sbjct: 120 GVTGGPKSREHG-LVCLVGGTDETIAKVRPVLDGFAKLVAHMGGPGAGMAAKIARNVIV 177
>UniRef50_Q033P2 Cluster: 3-hydroxyisobutyrate dehydrogenase related
beta-hydroxyacid dehydrogenase; n=1; Lactobacillus casei
ATCC 334|Rep: 3-hydroxyisobutyrate dehydrogenase related
beta-hydroxyacid dehydrogenase - Lactobacillus casei
(strain ATCC 334)
Length = 285
Score = 52.0 bits (119), Expect = 5e-06
Identities = 35/118 (29%), Positives = 59/118 (50%), Gaps = 1/118 (0%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKD-GVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTD 177
++ S+++ + L + + G+V + + GS LI +ST+DP I + K D
Sbjct: 60 IITSVMSDDVPALHIGTTETPGIVHYLQPGSTLIVTSTLDPRKITAIQAVMPTK-THLLD 118
Query: 178 APVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNM 351
P+ GGV A+ A L +A G K+ P+LK G ++ G+ G+G KL N+
Sbjct: 119 VPMIGGVKYAREAGLVLIAAGDKQAVADVTPILKTFGTVKY-VGEQGNGAKLKLITNV 175
>UniRef50_A5CN67 Cluster: Putative beta-hydroxyacid dehydrogenase;
n=1; Clavibacter michiganensis subsp. michiganensis
NCPPB 382|Rep: Putative beta-hydroxyacid dehydrogenase -
Clavibacter michiganensis subsp. michiganensis (strain
NCPPB 382)
Length = 291
Score = 52.0 bits (119), Expect = 5e-06
Identities = 37/138 (26%), Positives = 63/138 (45%), Gaps = 1/138 (0%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
VVV +L VL+V V + G++++ SST+ ++I +A E + F DA
Sbjct: 57 VVVVMLFDADAVLEVLAE---VAPALRPGAVVLQSSTVGVEGTRRIAALAAEHAVRFVDA 113
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCG-QIGSGQVAKLTNNMLM 357
PV G A+ L + G ++D + P+L+ G++ G G G KL N +
Sbjct: 114 PVLGTRGPAEQGLLVHLVSGSEDDLAVARPVLEATGSRTVVAGSDAGPGSALKLACNAWI 173
Query: 358 GITGMATAECMNMGIKMG 411
AT + + + +G
Sbjct: 174 ASITAATGQSLGLARLLG 191
>UniRef50_A0QZR7 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Mycobacterium smegmatis str. MC2 155|Rep:
3-hydroxyisobutyrate dehydrogenase - Mycobacterium
smegmatis (strain ATCC 700084 / mc(2)155)
Length = 299
Score = 51.6 bits (118), Expect = 6e-06
Identities = 34/109 (31%), Positives = 50/109 (45%), Gaps = 1/109 (0%)
Frame = +1
Query: 88 SLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSL 267
+++++ ST+ + G G DAPVSGG GA+ +L MA G E+
Sbjct: 89 TVVVNLSTVGRQALTEAADALTHAGYGCLDAPVSGGAEGARTGSLTIMASGDPTTIEQCS 148
Query: 268 PLLKVMGAKQFHCG-QIGSGQVAKLTNNMLMGITGMATAECMNMGIKMG 411
+ V+ K G Q G Q K+ NN+L +ATAE + K G
Sbjct: 149 SVFDVIAGKVIVVGNQPGQAQAIKVANNVLSLGALVATAEATAITRKAG 197
>UniRef50_Q21ZT0 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Rhodoferax ferrireducens T118|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Rhodoferax ferrireducens (strain DSM 15236 / ATCC
BAA-621 / T118)
Length = 315
Score = 51.2 bits (117), Expect = 8e-06
Identities = 36/137 (26%), Positives = 62/137 (45%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
V + + S +V VY G DG++ + G +++D++T DP ++ +G + DA
Sbjct: 65 VFLCVNGSPQVEACVY-GADGLLEGLRAGGVVVDATTADPVSTLKVAAAVQARGGRYVDA 123
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
P++ A++ + M GG PL++ F G++GSG KL +N +
Sbjct: 124 PMTRTSQHAEDGCVNAMLGGDAVTIAEVRPLIEAYAENIFIGGEVGSGHRLKLLHNYISL 183
Query: 361 ITGMATAECMNMGIKMG 411
T AE K G
Sbjct: 184 GTLALLAEAYTCAGKAG 200
>UniRef50_A4BV63 Cluster: 3-hydroxyacid dehydrogenase; n=1;
Nitrococcus mobilis Nb-231|Rep: 3-hydroxyacid
dehydrogenase - Nitrococcus mobilis Nb-231
Length = 227
Score = 50.8 bits (116), Expect = 1e-05
Identities = 30/114 (26%), Positives = 53/114 (46%)
Frame = +1
Query: 49 LGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAF 228
LG D + + +I +TI P+ KQ+ +G + ++PV G + A++ L
Sbjct: 12 LGIDEADGPSFARTTVIQMATIAPSESKQLMSAVARRGGDYFESPVLGSLPEAKSGNLIL 71
Query: 229 MAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECM 390
M G +E F + +L + G G +G+G KL N L+ +A +E +
Sbjct: 72 MVGATEEQFVKWRDILALFGPTPRLIGPVGAGACVKLAMNQLIAALTIAFSESL 125
>UniRef50_A6RMW8 Cluster: Putative uncharacterized protein; n=2;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 446
Score = 50.4 bits (115), Expect = 1e-05
Identities = 38/143 (26%), Positives = 68/143 (47%), Gaps = 6/143 (4%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDP-NVP--KQIFPIALE-KGLG 168
+V+ + T+ + + ++ G + + + +I SST P +VP +++ K +
Sbjct: 65 IVIMVATAAQTLAVLFDDVTGAIHELQPNATIILSSTAFPEHVPEVRELLDNKYNRKDVE 124
Query: 169 FTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHC--GQIGSGQVAKLT 342
DAPVSGG A TL +A G ++ + + P+L M A H G +G+G K+
Sbjct: 125 LVDAPVSGGTSRAALGTLVILASGPEKSLDAAKPVLDAM-ADPLHMIPGGLGAGTKVKMV 183
Query: 343 NNMLMGITGMATAECMNMGIKMG 411
+ L GI + +E M +G
Sbjct: 184 HQALAGIHMIMASEAMGFAAFLG 206
>UniRef50_Q0W2D7 Cluster: Putative 6-phosphogluconate dehydrogenase;
n=1; uncultured methanogenic archaeon RC-I|Rep: Putative
6-phosphogluconate dehydrogenase - Uncultured
methanogenic archaeon RC-I
Length = 310
Score = 50.4 bits (115), Expect = 1e-05
Identities = 33/101 (32%), Positives = 52/101 (51%), Gaps = 4/101 (3%)
Frame = +1
Query: 58 DGVVAHAKKGSLLID--SSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFM 231
+ ++ H ++G +L+D +S +V ++ +KG D SGGV GA+ FM
Sbjct: 76 ESLIPHLERGDVLMDGGNSFFRDSVARE--EALRKKGFRLLDCGTSGGVDGARTGA-CFM 132
Query: 232 AGGRKEDFERSLPLLKVMGAK--QFHCGQIGSGQVAKLTNN 348
GG +E FE + P+LK + + G GSG AKL +N
Sbjct: 133 VGGSREGFELAEPVLKKLAVDGGVLYTGSPGSGHYAKLVHN 173
>UniRef50_O34969 Cluster: Uncharacterized oxidoreductase yfjR; n=1;
Bacillus subtilis|Rep: Uncharacterized oxidoreductase
yfjR - Bacillus subtilis
Length = 261
Score = 50.4 bits (115), Expect = 1e-05
Identities = 38/138 (27%), Positives = 62/138 (44%), Gaps = 1/138 (0%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
+V+++L + V V G+DG++ + + I STI +++ EKG F A
Sbjct: 34 IVITMLADDDSVSTVTFGEDGLLEGLAENGIHISMSTISVEFSEKLAAAHAEKGQFFLAA 93
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIG-SGQVAKLTNNMLM 357
PV G A A L + G E + + PLL + + F G+ + AK++ N L+
Sbjct: 94 PVLGRPDAAAKAALRIITAGPAEAKQAAKPLLDSLSQQIFDVGEESKTANAAKISINFLL 153
Query: 358 GITGMATAECMNMGIKMG 411
A +E M K G
Sbjct: 154 VSMLEALSESFLMMEKYG 171
>UniRef50_Q6RXW5 Cluster: Succinic semialdehyde dehydrogenase; n=2;
Rhodococcus|Rep: Succinic semialdehyde dehydrogenase -
Rhodococcus sp. TK6
Length = 262
Score = 50.0 bits (114), Expect = 2e-05
Identities = 35/119 (29%), Positives = 57/119 (47%), Gaps = 1/119 (0%)
Frame = +1
Query: 58 DGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATL-AFMA 234
+ + AH + + +T+ P ++I P A G +APVSGG GA++ ++ F+A
Sbjct: 76 EALAAHTAQPLTVFVHTTLAPADARKILPSA-PAGWRVFEAPVSGGPQGARHGSMTVFLA 134
Query: 235 GGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMG 411
G D E + LL+ + + F G + KL NN L ATA +N+ + G
Sbjct: 135 GPAPTDAENA--LLEDISGRVFQMESYGQPALVKLLNNALATYNLAATARMLNLAAEHG 191
>UniRef50_Q1NHG5 Cluster: Putative uncharacterized protein; n=1;
Sphingomonas sp. SKA58|Rep: Putative uncharacterized
protein - Sphingomonas sp. SKA58
Length = 265
Score = 49.6 bits (113), Expect = 2e-05
Identities = 33/118 (27%), Positives = 49/118 (41%)
Frame = +1
Query: 58 DGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAG 237
D ++ K+G+ L+ STI P +QI A G+ DAPV+ M + M G
Sbjct: 64 DALLPVMKRGASLLIHSTIKPKTAQQIAERAATVGVDVIDAPVTRTEMTKNGPFVFCMTG 123
Query: 238 GRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMG 411
G + R +L H G +GS K+ NN++ M E N+ G
Sbjct: 124 GDEAVAARVQIVLDAFSTNTMHIGPLGSAMALKICNNLISWCGIMLGVEVANVAEASG 181
>UniRef50_A3Q3U7 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Mycobacterium|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Mycobacterium sp. (strain
JLS)
Length = 279
Score = 49.6 bits (113), Expect = 2e-05
Identities = 36/137 (26%), Positives = 55/137 (40%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
V++S L S+ + + LG +G +A+AK ++ + S T G DA
Sbjct: 61 VLISCLFSDAQLRETGLGPNGFIANAKPAAVFV-SHTTGTVATLTALRDHSSSGPVVLDA 119
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
PVSG TL + GG + P+L G +GS KL NN+L
Sbjct: 120 PVSGTADDIAAGTLTVLLGGPADAVAAVTPVLAAYADPLVPTGTLGSALALKLINNLLFA 179
Query: 361 ITGMATAECMNMGIKMG 411
A +G ++G
Sbjct: 180 ANAQLLAAATELGTQLG 196
>UniRef50_Q8YRT5 Cluster: 3-hydroxyacid dehydrogenase; n=5;
Cyanobacteria|Rep: 3-hydroxyacid dehydrogenase -
Anabaena sp. (strain PCC 7120)
Length = 292
Score = 49.2 bits (112), Expect = 3e-05
Identities = 34/118 (28%), Positives = 51/118 (43%)
Frame = +1
Query: 4 VVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 183
V+ +LT+ + V L +G +I TI ++I + G + +AP
Sbjct: 60 VILMLTNAAAIYHVLLSDTSW--RTLQGRTIIQMGTITSTQSQEIRDSIVGGGGEYIEAP 117
Query: 184 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLM 357
V G + AQ TL M G + +ER L LLK G G +G+ KL N L+
Sbjct: 118 VLGSIPEAQAGTLTVMVGAEPQQYERCLNLLKNFGPDPLLIGPVGTASGLKLALNQLI 175
>UniRef50_Q5GUM4 Cluster: Dehydrogenase; n=5;
Gammaproteobacteria|Rep: Dehydrogenase - Xanthomonas
oryzae pv. oryzae
Length = 335
Score = 48.8 bits (111), Expect = 4e-05
Identities = 37/136 (27%), Positives = 62/136 (45%), Gaps = 3/136 (2%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
++ S+L + V L + GV+ GS+ ++ +TI + + + E+G+ + A
Sbjct: 101 LLFSMLADDDAVRQTLLER-GVLDALPAGSVHVNMATISVALAHALTALHAERGVAYVAA 159
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQI-GSGQVAKLTNNMLM 357
PV G V A+ L +AGG R P+ +G K +H G+ AKL N+ +
Sbjct: 160 PVLGRVDVAEAGKLNILAGGDDVAVARVQPMFDALGQKTWHIGRAPEQANAAKLAANVCL 219
Query: 358 --GITGMATAECMNMG 399
I MA A + G
Sbjct: 220 ASAIGAMAEASALARG 235
>UniRef50_A7DWL2 Cluster: Putative dehydrogenase; n=1; Streptomyces
tendae|Rep: Putative dehydrogenase - Streptomyces tendae
Length = 293
Score = 48.8 bits (111), Expect = 4e-05
Identities = 33/130 (25%), Positives = 57/130 (43%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
VV+ L V +V G+ VV + G++L+D++T+ P+ + G+ +A
Sbjct: 61 VVLLSLADEPAVDEVLFGE--VVWQLQPGTVLVDTTTVSPSFARNTAVRLAASGVERLEA 118
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 360
V G A++ L G + + +L +G + H G G KL N+L+G
Sbjct: 119 CVMGNPEMAESGRLRIFTSGSHSAVDAAGDVLSALGQEVRHLGDAGRASALKLALNLLLG 178
Query: 361 ITGMATAECM 390
I AE +
Sbjct: 179 IQTAGLAEAV 188
>UniRef50_A3ES45 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Leptospirillum sp. Group II UBA|Rep:
3-hydroxyisobutyrate dehydrogenase - Leptospirillum sp.
Group II UBA
Length = 307
Score = 48.8 bits (111), Expect = 4e-05
Identities = 35/139 (25%), Positives = 65/139 (46%), Gaps = 2/139 (1%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
+V ++L + V + L + G++ +G + + T+ P ++ E+G A
Sbjct: 70 LVFTMLADDAAVKETVLKEGGLLDSLPQGGVHVSMGTLSPGFVLELSKTHTERGQILVSA 129
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGS--GQVAKLTNNML 354
PV G A+ TL +A G ++ E LPLL+ +G+ F G+ S + L N L
Sbjct: 130 PVFGRPDRAEAGTLTIVAAGPQKTLESLLPLLEHLGSPVFCVGEDPSLANHIKVLGNFTL 189
Query: 355 MGITGMATAECMNMGIKMG 411
G+ AE +++ ++G
Sbjct: 190 AGLL-ETLAESLSLARRVG 207
>UniRef50_Q0SAG5 Cluster: Phosphogluconate dehydrogenase; n=23;
Actinobacteria (class)|Rep: Phosphogluconate
dehydrogenase - Rhodococcus sp. (strain RHA1)
Length = 303
Score = 48.4 bits (110), Expect = 6e-05
Identities = 36/122 (29%), Positives = 57/122 (46%), Gaps = 6/122 (4%)
Frame = +1
Query: 1 VVVSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 180
VV ++ + K+ D V+ + G L+ID K + +G+G+ D
Sbjct: 53 VVWVMVPAGKITQDTVTELSSVL---ETGDLVIDGGNSRYTDDKVHGELLGSRGIGYLDC 109
Query: 181 PVSGGVMGAQNATLAFMAGGRKEDFERSLPL---LKVMGAKQ---FHCGQIGSGQVAKLT 342
VSGGV G ++ M GG D ER+LP+ L+ G + H G +G+G AK+
Sbjct: 110 GVSGGVWGLEDG-YGMMVGGSDADVERALPIFDALRPEGERADGFVHAGPVGAGHYAKMI 168
Query: 343 NN 348
+N
Sbjct: 169 HN 170
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 480,514,607
Number of Sequences: 1657284
Number of extensions: 10210773
Number of successful extensions: 31240
Number of sequences better than 10.0: 320
Number of HSP's better than 10.0 without gapping: 29982
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 31150
length of database: 575,637,011
effective HSP length: 92
effective length of database: 423,166,883
effective search space used: 19042509735
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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