Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmte6l06
(624 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Y14487-1|CAB54840.1| 347|Homo sapiens cytosolic serine hydroxym... 106 7e-23
Y14485-1|CAB54838.1| 483|Homo sapiens cytosolic serine hydroxym... 106 7e-23
L23928-3|AAA36019.1| 403|Homo sapiens serine hydroxymethyltrans... 106 7e-23
L23928-2|AAA36018.1| 444|Homo sapiens serine hydroxymethyltrans... 106 7e-23
L23928-1|AAA36020.1| 483|Homo sapiens serine hydroxymethyltrans... 106 7e-23
L11931-1|AAA63257.1| 483|Homo sapiens serine hydroxymethyltrans... 106 7e-23
BC038598-1|AAH38598.1| 483|Homo sapiens serine hydroxymethyltra... 106 7e-23
BC022874-1|AAH22874.1| 444|Homo sapiens serine hydroxymethyltra... 106 7e-23
BC007979-1|AAH07979.1| 483|Homo sapiens serine hydroxymethyltra... 106 7e-23
AK223552-1|BAD97272.1| 483|Homo sapiens serine hydroxymethyltra... 106 7e-23
U23143-1|AAA64572.1| 483|Homo sapiens mitochondrial serine hydr... 100 4e-21
L11932-1|AAA63258.1| 474|Homo sapiens serine hydroxymethyltrans... 100 4e-21
BT006866-1|AAP35512.1| 504|Homo sapiens serine hydroxymethyltra... 100 4e-21
BC044211-1|AAH44211.1| 504|Homo sapiens serine hydroxymethyltra... 100 4e-21
BC032584-1|AAH32584.1| 494|Homo sapiens SHMT2 protein protein. 100 4e-21
BC013677-1|AAH13677.1| 504|Homo sapiens serine hydroxymethyltra... 100 4e-21
BC011911-1|AAH11911.1| 504|Homo sapiens serine hydroxymethyltra... 100 4e-21
AK223555-1|BAD97275.1| 504|Homo sapiens serine hydroxymethyltra... 100 4e-21
AK055053-1|BAB70847.1| 135|Homo sapiens protein. 40 0.009
BC091501-1|AAH91501.1| 480|Homo sapiens SHMT2 protein protein. 36 0.15
Y14488-1|CAB54841.1| 129|Homo sapiens 14 kDa protein protein. 34 0.36
>Y14487-1|CAB54840.1| 347|Homo sapiens cytosolic serine
hydroxymethyltransferase protein.
Length = 347
Score = 106 bits (254), Expect = 7e-23
Identities = 49/81 (60%), Positives = 62/81 (76%)
Frame = +1
Query: 382 KLLNSNLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPN 561
K+L L ++D E+++II KE +RQR GLE+IASENF S VL+ L SCL+NKYSEG P
Sbjct: 20 KMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPG 79
Query: 562 QRYYGGNEYIDEIEILAQNRS 624
QRYYGG E+IDE+E L Q R+
Sbjct: 80 QRYYGGTEFIDELETLCQKRA 100
>Y14485-1|CAB54838.1| 483|Homo sapiens cytosolic serine
hydroxymethyltransferase protein.
Length = 483
Score = 106 bits (254), Expect = 7e-23
Identities = 49/81 (60%), Positives = 62/81 (76%)
Frame = +1
Query: 382 KLLNSNLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPN 561
K+L L ++D E+++II KE +RQR GLE+IASENF S VL+ L SCL+NKYSEG P
Sbjct: 20 KMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPG 79
Query: 562 QRYYGGNEYIDEIEILAQNRS 624
QRYYGG E+IDE+E L Q R+
Sbjct: 80 QRYYGGTEFIDELETLCQKRA 100
>L23928-3|AAA36019.1| 403|Homo sapiens serine
hydroxymethyltransferase protein.
Length = 403
Score = 106 bits (254), Expect = 7e-23
Identities = 49/81 (60%), Positives = 62/81 (76%)
Frame = +1
Query: 382 KLLNSNLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPN 561
K+L L ++D E+++II KE +RQR GLE+IASENF S VL+ L SCL+NKYSEG P
Sbjct: 20 KMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPG 79
Query: 562 QRYYGGNEYIDEIEILAQNRS 624
QRYYGG E+IDE+E L Q R+
Sbjct: 80 QRYYGGTEFIDELETLCQKRA 100
>L23928-2|AAA36018.1| 444|Homo sapiens serine
hydroxymethyltransferase protein.
Length = 444
Score = 106 bits (254), Expect = 7e-23
Identities = 49/81 (60%), Positives = 62/81 (76%)
Frame = +1
Query: 382 KLLNSNLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPN 561
K+L L ++D E+++II KE +RQR GLE+IASENF S VL+ L SCL+NKYSEG P
Sbjct: 20 KMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPG 79
Query: 562 QRYYGGNEYIDEIEILAQNRS 624
QRYYGG E+IDE+E L Q R+
Sbjct: 80 QRYYGGTEFIDELETLCQKRA 100
>L23928-1|AAA36020.1| 483|Homo sapiens serine
hydroxymethyltransferase protein.
Length = 483
Score = 106 bits (254), Expect = 7e-23
Identities = 49/81 (60%), Positives = 62/81 (76%)
Frame = +1
Query: 382 KLLNSNLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPN 561
K+L L ++D E+++II KE +RQR GLE+IASENF S VL+ L SCL+NKYSEG P
Sbjct: 20 KMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPG 79
Query: 562 QRYYGGNEYIDEIEILAQNRS 624
QRYYGG E+IDE+E L Q R+
Sbjct: 80 QRYYGGTEFIDELETLCQKRA 100
>L11931-1|AAA63257.1| 483|Homo sapiens serine
hydroxymethyltransferase protein.
Length = 483
Score = 106 bits (254), Expect = 7e-23
Identities = 49/81 (60%), Positives = 62/81 (76%)
Frame = +1
Query: 382 KLLNSNLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPN 561
K+L L ++D E+++II KE +RQR GLE+IASENF S VL+ L SCL+NKYSEG P
Sbjct: 20 KMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPG 79
Query: 562 QRYYGGNEYIDEIEILAQNRS 624
QRYYGG E+IDE+E L Q R+
Sbjct: 80 QRYYGGTEFIDELETLCQKRA 100
>BC038598-1|AAH38598.1| 483|Homo sapiens serine
hydroxymethyltransferase 1 (soluble) protein.
Length = 483
Score = 106 bits (254), Expect = 7e-23
Identities = 49/81 (60%), Positives = 62/81 (76%)
Frame = +1
Query: 382 KLLNSNLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPN 561
K+L L ++D E+++II KE +RQR GLE+IASENF S VL+ L SCL+NKYSEG P
Sbjct: 20 KMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPG 79
Query: 562 QRYYGGNEYIDEIEILAQNRS 624
QRYYGG E+IDE+E L Q R+
Sbjct: 80 QRYYGGTEFIDELETLCQKRA 100
>BC022874-1|AAH22874.1| 444|Homo sapiens serine
hydroxymethyltransferase 1 (soluble) protein.
Length = 444
Score = 106 bits (254), Expect = 7e-23
Identities = 49/81 (60%), Positives = 62/81 (76%)
Frame = +1
Query: 382 KLLNSNLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPN 561
K+L L ++D E+++II KE +RQR GLE+IASENF S VL+ L SCL+NKYSEG P
Sbjct: 20 KMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPG 79
Query: 562 QRYYGGNEYIDEIEILAQNRS 624
QRYYGG E+IDE+E L Q R+
Sbjct: 80 QRYYGGTEFIDELETLCQKRA 100
>BC007979-1|AAH07979.1| 483|Homo sapiens serine
hydroxymethyltransferase 1 (soluble) protein.
Length = 483
Score = 106 bits (254), Expect = 7e-23
Identities = 49/81 (60%), Positives = 62/81 (76%)
Frame = +1
Query: 382 KLLNSNLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPN 561
K+L L ++D E+++II KE +RQR GLE+IASENF S VL+ L SCL+NKYSEG P
Sbjct: 20 KMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPG 79
Query: 562 QRYYGGNEYIDEIEILAQNRS 624
QRYYGG E+IDE+E L Q R+
Sbjct: 80 QRYYGGTEFIDELETLCQKRA 100
>AK223552-1|BAD97272.1| 483|Homo sapiens serine
hydroxymethyltransferase 1 (soluble) isoform 1 variant
protein.
Length = 483
Score = 106 bits (254), Expect = 7e-23
Identities = 49/81 (60%), Positives = 62/81 (76%)
Frame = +1
Query: 382 KLLNSNLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPN 561
K+L L ++D E+++II KE +RQR GLE+IASENF S VL+ L SCL+NKYSEG P
Sbjct: 20 KMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPG 79
Query: 562 QRYYGGNEYIDEIEILAQNRS 624
QRYYGG E+IDE+E L Q R+
Sbjct: 80 QRYYGGTEFIDELETLCQKRA 100
>U23143-1|AAA64572.1| 483|Homo sapiens mitochondrial serine
hydroxymethyltransferase protein.
Length = 483
Score = 100 bits (240), Expect = 4e-21
Identities = 44/76 (57%), Positives = 60/76 (78%)
Frame = +1
Query: 397 NLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPNQRYYG 576
+L ++DPE+++++ +EKDRQ GLE+IASENF S L+ L SCL+NKYSEG P +RYYG
Sbjct: 27 SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYG 86
Query: 577 GNEYIDEIEILAQNRS 624
G E +DEIE+L Q R+
Sbjct: 87 GAEVVDEIELLCQRRA 102
>L11932-1|AAA63258.1| 474|Homo sapiens serine
hydroxymethyltransferase protein.
Length = 474
Score = 100 bits (240), Expect = 4e-21
Identities = 44/76 (57%), Positives = 60/76 (78%)
Frame = +1
Query: 397 NLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPNQRYYG 576
+L ++DPE+++++ +EKDRQ GLE+IASENF S L+ L SCL+NKYSEG P +RYYG
Sbjct: 18 SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYG 77
Query: 577 GNEYIDEIEILAQNRS 624
G E +DEIE+L Q R+
Sbjct: 78 GAEVVDEIELLCQRRA 93
>BT006866-1|AAP35512.1| 504|Homo sapiens serine
hydroxymethyltransferase 2 (mitochondrial) protein.
Length = 504
Score = 100 bits (240), Expect = 4e-21
Identities = 44/76 (57%), Positives = 60/76 (78%)
Frame = +1
Query: 397 NLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPNQRYYG 576
+L ++DPE+++++ +EKDRQ GLE+IASENF S L+ L SCL+NKYSEG P +RYYG
Sbjct: 48 SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYG 107
Query: 577 GNEYIDEIEILAQNRS 624
G E +DEIE+L Q R+
Sbjct: 108 GAEVVDEIELLCQRRA 123
>BC044211-1|AAH44211.1| 504|Homo sapiens serine
hydroxymethyltransferase 2 (mitochondrial) protein.
Length = 504
Score = 100 bits (240), Expect = 4e-21
Identities = 44/76 (57%), Positives = 60/76 (78%)
Frame = +1
Query: 397 NLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPNQRYYG 576
+L ++DPE+++++ +EKDRQ GLE+IASENF S L+ L SCL+NKYSEG P +RYYG
Sbjct: 48 SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYG 107
Query: 577 GNEYIDEIEILAQNRS 624
G E +DEIE+L Q R+
Sbjct: 108 GAEVVDEIELLCQRRA 123
>BC032584-1|AAH32584.1| 494|Homo sapiens SHMT2 protein protein.
Length = 494
Score = 100 bits (240), Expect = 4e-21
Identities = 44/76 (57%), Positives = 60/76 (78%)
Frame = +1
Query: 397 NLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPNQRYYG 576
+L ++DPE+++++ +EKDRQ GLE+IASENF S L+ L SCL+NKYSEG P +RYYG
Sbjct: 48 SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYG 107
Query: 577 GNEYIDEIEILAQNRS 624
G E +DEIE+L Q R+
Sbjct: 108 GAEVVDEIELLCQRRA 123
>BC013677-1|AAH13677.1| 504|Homo sapiens serine
hydroxymethyltransferase 2 (mitochondrial) protein.
Length = 504
Score = 100 bits (240), Expect = 4e-21
Identities = 44/76 (57%), Positives = 60/76 (78%)
Frame = +1
Query: 397 NLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPNQRYYG 576
+L ++DPE+++++ +EKDRQ GLE+IASENF S L+ L SCL+NKYSEG P +RYYG
Sbjct: 48 SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYG 107
Query: 577 GNEYIDEIEILAQNRS 624
G E +DEIE+L Q R+
Sbjct: 108 GAEVVDEIELLCQRRA 123
>BC011911-1|AAH11911.1| 504|Homo sapiens serine
hydroxymethyltransferase 2 (mitochondrial) protein.
Length = 504
Score = 100 bits (240), Expect = 4e-21
Identities = 44/76 (57%), Positives = 60/76 (78%)
Frame = +1
Query: 397 NLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPNQRYYG 576
+L ++DPE+++++ +EKDRQ GLE+IASENF S L+ L SCL+NKYSEG P +RYYG
Sbjct: 48 SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYG 107
Query: 577 GNEYIDEIEILAQNRS 624
G E +DEIE+L Q R+
Sbjct: 108 GAEVVDEIELLCQRRA 123
>AK223555-1|BAD97275.1| 504|Homo sapiens serine
hydroxymethyltransferase 2 (mitochondrial) variant
protein.
Length = 504
Score = 100 bits (240), Expect = 4e-21
Identities = 44/76 (57%), Positives = 60/76 (78%)
Frame = +1
Query: 397 NLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPNQRYYG 576
+L ++DPE+++++ +EKDRQ GLE+IASENF S L+ L SCL+NKYSEG P +RYYG
Sbjct: 48 SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYG 107
Query: 577 GNEYIDEIEILAQNRS 624
G E +DEIE+L Q R+
Sbjct: 108 GAEVVDEIELLCQRRA 123
>AK055053-1|BAB70847.1| 135|Homo sapiens protein.
Length = 135
Score = 39.5 bits (88), Expect = 0.009
Identities = 16/30 (53%), Positives = 26/30 (86%)
Frame = +1
Query: 397 NLWEADPELFDIIVKEKDRQRAGLEMIASE 486
+L ++DPE+++++ +EKDRQ GLE+IASE
Sbjct: 48 SLSDSDPEMWELLQREKDRQCRGLELIASE 77
>BC091501-1|AAH91501.1| 480|Homo sapiens SHMT2 protein protein.
Length = 480
Score = 35.5 bits (78), Expect = 0.15
Identities = 14/21 (66%), Positives = 17/21 (80%)
Frame = +1
Query: 562 QRYYGGNEYIDEIEILAQNRS 624
QRYYGG E +DEIE+L Q R+
Sbjct: 79 QRYYGGAEVVDEIELLCQRRA 99
>Y14488-1|CAB54841.1| 129|Homo sapiens 14 kDa protein protein.
Length = 129
Score = 34.3 bits (75), Expect = 0.36
Identities = 13/20 (65%), Positives = 16/20 (80%)
Frame = +1
Query: 565 RYYGGNEYIDEIEILAQNRS 624
RYYGG E+IDE+E L Q R+
Sbjct: 65 RYYGGTEFIDELETLCQKRA 84
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 86,295,386
Number of Sequences: 237096
Number of extensions: 1682016
Number of successful extensions: 3203
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 3158
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3203
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 6747805200
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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