Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmte6a22
(619 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q9VH08 Cluster: CG6284-PA; n=9; Eumetazoa|Rep: CG6284-P... 184 2e-45
UniRef50_Q8N6T7-2 Cluster: Isoform 2 of Q8N6T7 ; n=5; Catarrhini... 143 3e-33
UniRef50_Q8N6T7 Cluster: Mono-ADP-ribosyltransferase sirtuin-6; ... 143 3e-33
UniRef50_Q9FE17 Cluster: Sir2-like protein; n=9; Magnoliophyta|R... 130 2e-29
UniRef50_A5AF92 Cluster: Putative uncharacterized protein; n=1; ... 109 5e-23
UniRef50_Q7SB01 Cluster: Putative uncharacterized protein NCU076... 106 5e-22
UniRef50_UPI0000D573CE Cluster: PREDICTED: similar to CG11305-PA... 103 3e-21
UniRef50_Q9NRC8 Cluster: NAD-dependent deacetylase sirtuin-7; n=... 101 1e-20
UniRef50_Q175I4 Cluster: Chromatin regulatory protein sir2; n=3;... 97 2e-19
UniRef50_UPI00015B56BB Cluster: PREDICTED: similar to ENSANGP000... 97 3e-19
UniRef50_Q9VAQ1 Cluster: CG11305-PA; n=8; Coelomata|Rep: CG11305... 91 2e-17
UniRef50_A5K3P4 Cluster: Putative uncharacterized protein; n=1; ... 86 6e-16
UniRef50_Q4UH74 Cluster: Sir2-like histone deacetylase, putative... 84 3e-15
UniRef50_Q7RP35 Cluster: Sir2-like protein; n=5; Plasmodium (Vin... 82 9e-15
UniRef50_Q1MT39 Cluster: Novel protein similar to vertebratesirt... 81 2e-14
UniRef50_Q8N6T7-3 Cluster: Isoform 3 of Q8N6T7 ; n=2; Catarrhini... 81 2e-14
UniRef50_Q8IKW2 Cluster: Putative uncharacterized protein; n=1; ... 80 4e-14
UniRef50_UPI0000E49846 Cluster: PREDICTED: similar to Sirtuin (s... 79 1e-13
UniRef50_A7AWG1 Cluster: Transcriptional regulator, Sir2 family ... 79 1e-13
UniRef50_Q22KA8 Cluster: Transcriptional regulator, Sir2 family ... 77 3e-13
UniRef50_UPI00006CB0CC Cluster: transcriptional regulator, Sir2 ... 70 4e-11
UniRef50_Q29QS4 Cluster: IP11347p; n=1; Drosophila melanogaster|... 69 7e-11
UniRef50_Q95Q89 Cluster: Yeast sir related protein 2.4; n=2; Cae... 67 3e-10
UniRef50_UPI000049979A Cluster: Sir2 family transcriptional regu... 59 1e-07
UniRef50_Q2LSF2 Cluster: Sir2 family of NAD+-dependent deacetyla... 58 2e-07
UniRef50_A6DC77 Cluster: Silent information regulator protein Si... 58 2e-07
UniRef50_A4M603 Cluster: Silent information regulator protein Si... 57 4e-07
UniRef50_A3ZMQ7 Cluster: Sir2 family, possible ADP ribosyltransf... 57 4e-07
UniRef50_Q3F1F4 Cluster: SIR2 family protein; n=1; Bacillus thur... 56 5e-07
UniRef50_Q89LY4 Cluster: NAD-dependent deacetylase 1; n=12; Prot... 56 5e-07
UniRef50_Q974M6 Cluster: NAD-dependent deacetylase; n=8; Thermop... 56 7e-07
UniRef50_Q8ZT00 Cluster: NAD-dependent deacetylase 2; n=2; cellu... 54 3e-06
UniRef50_UPI000049971A Cluster: Sir2 family transcriptional regu... 53 6e-06
UniRef50_Q0AY57 Cluster: Regulatory protein, sir2 family; n=1; S... 52 1e-05
UniRef50_A6P1S7 Cluster: Putative uncharacterized protein; n=2; ... 52 1e-05
UniRef50_Q8R984 Cluster: NAD-dependent deacetylase 2; n=1; Therm... 50 3e-05
UniRef50_Q3A6W7 Cluster: NAD-dependent protein deacetylases, SIR... 50 4e-05
UniRef50_A0NQ49 Cluster: Silent information regulator protein Si... 50 4e-05
UniRef50_Q54GV7 Cluster: NAD(+)-dependent deacetylase, silent in... 50 4e-05
UniRef50_A7EMW8 Cluster: Putative uncharacterized protein; n=1; ... 50 6e-05
UniRef50_Q8CJM9 Cluster: NAD-dependent deacetylase 2; n=3; Actin... 50 6e-05
UniRef50_Q5YR82 Cluster: Putative Sir2 family regulator; n=1; No... 49 8e-05
UniRef50_UPI00015B57C0 Cluster: PREDICTED: similar to GA18743-PA... 49 1e-04
UniRef50_Q2YZT2 Cluster: Putative uncharacterized protein; n=1; ... 49 1e-04
UniRef50_A7HL19 Cluster: Silent information regulator protein Si... 49 1e-04
UniRef50_A4J646 Cluster: Silent information regulator protein Si... 49 1e-04
UniRef50_A1HLU5 Cluster: Silent information regulator protein Si... 49 1e-04
UniRef50_Q8ZU41 Cluster: NAD-dependent deacetylase 1; n=3; Pyrob... 49 1e-04
UniRef50_Q3E2I1 Cluster: Silent information regulator protein Si... 48 1e-04
UniRef50_A4VDQ9 Cluster: Chromatin regulatory protein sir2; n=1;... 48 2e-04
UniRef50_Q9WYW0 Cluster: NAD-dependent deacetylase; n=4; Thermot... 48 2e-04
UniRef50_A6RRE3 Cluster: Putative uncharacterized protein; n=1; ... 48 2e-04
UniRef50_Q5KZE8 Cluster: NAD-dependent deacetylase 2; n=3; Bacte... 48 2e-04
UniRef50_Q5KA61 Cluster: Histone deacetylase, putative; n=1; Fil... 47 3e-04
UniRef50_A6R1B0 Cluster: Predicted protein; n=2; Onygenales|Rep:... 47 3e-04
UniRef50_A2Q9C4 Cluster: Contig An01c0250, complete genome; n=18... 47 3e-04
UniRef50_Q8CNF4 Cluster: NAD-dependent deacetylase; n=17; Staphy... 47 3e-04
UniRef50_A7B9E8 Cluster: Putative uncharacterized protein; n=1; ... 47 4e-04
UniRef50_A1ZPG8 Cluster: NAD-dependent deacetylase; n=1; Microsc... 47 4e-04
UniRef50_O96505 Cluster: SIR2; n=4; Sophophora|Rep: SIR2 - Droso... 47 4e-04
UniRef50_Q5AQ47 Cluster: Potential Sir2 family histone deacetyla... 47 4e-04
UniRef50_Q12Y78 Cluster: Silent information regulator protein Si... 47 4e-04
UniRef50_A7DQD6 Cluster: Silent information regulator protein Si... 47 4e-04
UniRef50_Q8REC3 Cluster: NAD-dependent deacetylase; n=3; Fusobac... 47 4e-04
UniRef50_A1HU63 Cluster: Silent information regulator protein Si... 46 5e-04
UniRef50_Q23A43 Cluster: Transcriptional regulator, Sir2 family ... 46 5e-04
UniRef50_Q1RPU3 Cluster: Zinc finger protein; n=1; Ciona intesti... 46 5e-04
UniRef50_Q21921 Cluster: NAD-dependent deacetylase SIR2 homolog;... 46 5e-04
UniRef50_O07595 Cluster: NAD-dependent deacetylase; n=3; Bacillu... 46 5e-04
UniRef50_A6TNA0 Cluster: Silent information regulator protein Si... 46 7e-04
UniRef50_A6G0H3 Cluster: Silent information regulator protein Si... 46 7e-04
UniRef50_A6DES9 Cluster: Transcriptional regulator, Sir2 family ... 46 7e-04
UniRef50_Q2GZ88 Cluster: Putative uncharacterized protein; n=1; ... 46 7e-04
UniRef50_Q73KE1 Cluster: NAD-dependent deacetylase; n=1; Trepone... 46 7e-04
UniRef50_Q97MB4 Cluster: NAD-dependent deacetylase; n=7; Bacteri... 46 7e-04
UniRef50_Q5L014 Cluster: NAD-dependent deacetylase 1; n=7; Bacil... 46 7e-04
UniRef50_Q8FUC8 Cluster: NAD-dependent deacetylase 1; n=6; Coryn... 46 7e-04
UniRef50_A6PTK3 Cluster: Silent information regulator protein Si... 46 0.001
UniRef50_A5UYK2 Cluster: Silent information regulator protein Si... 46 0.001
UniRef50_Q5BVF7 Cluster: SJCHGC03105 protein; n=2; Schistosoma j... 46 0.001
UniRef50_A0LG97 Cluster: Silent information regulator protein Si... 45 0.001
UniRef50_Q9FY91 Cluster: SIR2-family protein; n=12; Magnoliophyt... 45 0.001
UniRef50_A7SX90 Cluster: Predicted protein; n=3; Eumetazoa|Rep: ... 45 0.001
UniRef50_A7EC18 Cluster: Putative uncharacterized protein; n=1; ... 45 0.001
UniRef50_UPI0000D55B5A Cluster: PREDICTED: similar to CG5216-PA;... 45 0.002
UniRef50_UPI000051AA14 Cluster: PREDICTED: similar to NAD-depend... 45 0.002
UniRef50_Q23E36 Cluster: Transcriptional regulator, Sir2 family ... 45 0.002
UniRef50_A2F8E1 Cluster: Transcriptional regulator, Sir2 family ... 45 0.002
UniRef50_Q7S386 Cluster: Putative uncharacterized protein NCU048... 45 0.002
UniRef50_Q6CB00 Cluster: Similarities with tr|Q9UR39 Schizosacch... 45 0.002
UniRef50_Q0CR31 Cluster: NAD-dependent histone deacetylase SIR2;... 45 0.002
UniRef50_A6RSV6 Cluster: Putative uncharacterized protein; n=2; ... 45 0.002
UniRef50_Q0LIC7 Cluster: Silent information regulator protein Si... 44 0.002
UniRef50_Q6CQA7 Cluster: Kluyveromyces lactis strain NRRL Y-1140... 44 0.002
UniRef50_Q0UNC9 Cluster: Putative uncharacterized protein; n=1; ... 44 0.002
UniRef50_A6RXY5 Cluster: Putative uncharacterized protein; n=2; ... 44 0.002
UniRef50_A1DG07 Cluster: SIR2 family histone deacetylase, putati... 44 0.002
UniRef50_Q67KQ0 Cluster: NAD-dependent deacetylase; n=1; Symbiob... 44 0.002
UniRef50_Q88ZA0 Cluster: NAD-dependent deacetylase; n=4; Lactoba... 44 0.002
UniRef50_UPI000023F1DF Cluster: hypothetical protein FG02466.1; ... 44 0.003
UniRef50_A4JS80 Cluster: Silent information regulator protein Si... 44 0.003
UniRef50_Q7S6G9 Cluster: Putative uncharacterized protein NCU047... 44 0.003
UniRef50_Q4WT50 Cluster: SIR2 family histone deacetylase (Hst4),... 44 0.003
UniRef50_Q046W9 Cluster: NAD-dependent protein deacetylase, SIR2... 43 0.005
UniRef50_Q7SCL4 Cluster: Putative uncharacterized protein NCU005... 43 0.005
UniRef50_A7TQE2 Cluster: Putative uncharacterized protein; n=1; ... 43 0.005
UniRef50_Q5V4Q5 Cluster: NAD-dependent deacetylase; n=2; Halobac... 43 0.005
UniRef50_Q011Q8 Cluster: NAD-dependent deacetylase SIRT2; n=2; O... 43 0.007
UniRef50_Q6BPH5 Cluster: Debaryomyces hansenii chromosome E of s... 43 0.007
UniRef50_Q0UMU7 Cluster: Putative uncharacterized protein; n=1; ... 43 0.007
UniRef50_O94066 Cluster: Transcription regulatory protein; n=6; ... 43 0.007
UniRef50_A2QFF9 Cluster: Complex: Sir2p is one of four Silent In... 43 0.007
UniRef50_Q96EB6 Cluster: NAD-dependent deacetylase sirtuin-1; n=... 43 0.007
UniRef50_Q9UR39 Cluster: NAD-dependent deacetylase hst4; n=1; Sc... 43 0.007
UniRef50_A7RMK8 Cluster: Predicted protein; n=5; Eumetazoa|Rep: ... 42 0.009
UniRef50_A0D0F1 Cluster: Chromosome undetermined scaffold_33, wh... 42 0.009
UniRef50_Q6C8V5 Cluster: Similar to tr|Q9FY91 Arabidopsis thalia... 42 0.009
UniRef50_Q6BPA4 Cluster: Debaryomyces hansenii chromosome E of s... 42 0.009
UniRef50_A5DSX8 Cluster: NAD-dependent histone deacetylase SIR2;... 42 0.009
UniRef50_A4RMS1 Cluster: Putative uncharacterized protein; n=2; ... 42 0.009
UniRef50_UPI0000E49AD8 Cluster: PREDICTED: similar to NAD-depend... 42 0.012
UniRef50_A3JEV2 Cluster: NAD-dependent deacetylase; n=2; Marinob... 42 0.012
UniRef50_Q5KPC9 Cluster: Hst3 protein, putative; n=2; Filobasidi... 42 0.012
UniRef50_Q4PG00 Cluster: Putative uncharacterized protein; n=1; ... 42 0.012
UniRef50_Q9NXA8 Cluster: NAD-dependent deacetylase sirtuin-5; n=... 42 0.012
UniRef50_Q8U1Q1 Cluster: NAD-dependent deacetylase; n=19; cellul... 42 0.012
UniRef50_UPI00004997CB Cluster: Sir2 family transcriptional regu... 42 0.016
UniRef50_A6Q2C0 Cluster: Transcriptional regulator, Sir2 family;... 42 0.016
UniRef50_A4JJP4 Cluster: Silent information regulator protein Si... 42 0.016
UniRef50_Q4QB33 Cluster: Sir2-family protein-like protein; n=4; ... 42 0.016
UniRef50_Q2H5A0 Cluster: Putative uncharacterized protein; n=1; ... 42 0.016
UniRef50_A5DNV7 Cluster: Putative uncharacterized protein; n=1; ... 42 0.016
UniRef50_O94640 Cluster: NAD-dependent histone deacetylase sir2;... 42 0.016
UniRef50_Q875P9 Cluster: HST1; n=1; Lachancea kluyveri|Rep: HST1... 41 0.021
UniRef50_Q6C219 Cluster: Yarrowia lipolytica chromosome F of str... 41 0.021
UniRef50_Q88BY5 Cluster: NAD-dependent deacetylase; n=9; Bacteri... 41 0.021
UniRef50_Q21KQ1 Cluster: Silent information regulator protein Si... 41 0.027
UniRef50_A1ZHW6 Cluster: NAD-dependent deacetylase; n=2; Microsc... 41 0.027
UniRef50_Q7QZ36 Cluster: GLP_464_21655_23334; n=1; Giardia lambl... 41 0.027
UniRef50_A4QUX8 Cluster: Putative uncharacterized protein; n=1; ... 41 0.027
UniRef50_Q899G3 Cluster: NAD-dependent deacetylase; n=19; cellul... 41 0.027
UniRef50_Q81NT6 Cluster: NAD-dependent deacetylase; n=11; Bacill... 41 0.027
UniRef50_UPI00015B4FA0 Cluster: PREDICTED: similar to chromatin ... 40 0.036
UniRef50_UPI0000D578DC Cluster: PREDICTED: similar to sirtuin 5 ... 40 0.036
UniRef50_UPI00006CA40C Cluster: transcriptional regulator, Sir2 ... 40 0.036
UniRef50_A6WG46 Cluster: Silent information regulator protein Si... 40 0.036
UniRef50_Q1EP52 Cluster: Transcriptional regulator Sir2 family p... 40 0.036
UniRef50_Q54QE6 Cluster: Zn finger-containing protein; n=5; Euka... 40 0.036
UniRef50_Q9USN7 Cluster: Sir2 family histone deacetylase Hst2; n... 40 0.036
UniRef50_Q5KG84 Cluster: Hst4 protein, putative; n=2; Filobasidi... 40 0.036
UniRef50_Q2HG51 Cluster: Putative uncharacterized protein; n=2; ... 40 0.036
UniRef50_A3LRA1 Cluster: Transcriptional regulatory protein; n=2... 40 0.036
UniRef50_A1CD03 Cluster: SIR2 family histone deacetylase, putati... 40 0.036
UniRef50_Q607X6 Cluster: NAD-dependent deacetylase; n=1; Methylo... 40 0.036
UniRef50_P53688 Cluster: NAD-dependent histone deacetylase HST4;... 40 0.036
UniRef50_UPI0000519F58 Cluster: PREDICTED: similar to Sirt4 CG31... 40 0.047
UniRef50_A1FG80 Cluster: Silent information regulator protein Si... 40 0.047
UniRef50_Q22ZC3 Cluster: Transcriptional regulator, Sir2 family ... 40 0.047
UniRef50_A0DQW0 Cluster: Chromosome undetermined scaffold_6, who... 40 0.047
UniRef50_Q6BVM7 Cluster: Similar to CA4170|IPF7784 Candida albic... 40 0.047
UniRef50_Q4WFZ3 Cluster: SIR2 family histone deacetylase, putati... 40 0.047
UniRef50_Q4P3S4 Cluster: Putative uncharacterized protein; n=1; ... 40 0.047
UniRef50_Q7ZVK3 Cluster: NAD-dependent deacetylase sirtuin-2; n=... 40 0.047
UniRef50_P53687 Cluster: NAD-dependent histone deacetylase HST3;... 40 0.047
UniRef50_UPI00015B48CB Cluster: PREDICTED: similar to 85 kda cal... 40 0.063
UniRef50_UPI000023E2DA Cluster: hypothetical protein FG00460.1; ... 40 0.063
UniRef50_Q1QTH0 Cluster: Silent information regulator protein Si... 40 0.063
UniRef50_A6LP94 Cluster: Silent information regulator protein Si... 40 0.063
UniRef50_Q8IRR5 Cluster: CG3187-PC, isoform C; n=4; Diptera|Rep:... 40 0.063
UniRef50_Q23YS7 Cluster: Transcriptional regulator, Sir2 family ... 40 0.063
UniRef50_A1CTI6 Cluster: SIR2 family histone deacetylase, putati... 40 0.063
UniRef50_Q8R216 Cluster: NAD-dependent deacetylase sirtuin-4; n=... 40 0.063
UniRef50_O59923 Cluster: NAD-dependent histone deacetylase SIR2;... 40 0.063
UniRef50_A4A980 Cluster: NAD-dependent deacetylase; n=5; Gammapr... 39 0.083
UniRef50_A1I9S7 Cluster: NAD-dependent deacetylase; n=1; Candida... 39 0.083
UniRef50_Q7PS76 Cluster: ENSANGP00000025231; n=1; Anopheles gamb... 39 0.083
UniRef50_Q54P49 Cluster: Zn finger-containing protein; n=1; Dict... 39 0.083
UniRef50_Q298C7 Cluster: GA18650-PA; n=1; Drosophila pseudoobscu... 39 0.083
UniRef50_Q5KDE0 Cluster: NAD-dependent histone deacetylase, puta... 39 0.083
UniRef50_Q9Y6E7 Cluster: NAD-dependent deacetylase sirtuin-4; n=... 39 0.083
UniRef50_P06700 Cluster: NAD-dependent histone deacetylase SIR2;... 39 0.083
UniRef50_Q839C6 Cluster: NAD-dependent deacetylase; n=14; Bacill... 39 0.083
UniRef50_Q885X7 Cluster: NAD-dependent deacetylase 2; n=4; Pseud... 39 0.083
UniRef50_UPI000050FCF4 Cluster: COG0846: NAD-dependent protein d... 39 0.11
UniRef50_Q4S7H2 Cluster: Chromosome 13 SCAF14715, whole genome s... 39 0.11
UniRef50_Q6AF12 Cluster: Regulatory protein, Sir2 family; n=2; A... 39 0.11
UniRef50_Q03ZB1 Cluster: NAD-dependent protein deacetylase, SIR2... 39 0.11
UniRef50_A0PU12 Cluster: Sir2-like regulatory protein; n=1; Myco... 39 0.11
UniRef50_Q8SSB6 Cluster: SIR2-LIKE PROTEIN INVOLVED IN TELOMERIC... 39 0.11
UniRef50_Q750H1 Cluster: AGL018Cp; n=1; Eremothecium gossypii|Re... 39 0.11
UniRef50_A5DJ74 Cluster: Putative uncharacterized protein; n=1; ... 39 0.11
UniRef50_A4RCT8 Cluster: Putative uncharacterized protein; n=3; ... 39 0.11
UniRef50_Q7WLE5 Cluster: NAD-dependent deacetylase; n=47; Bacter... 39 0.11
UniRef50_A7HID4 Cluster: Silent information regulator protein Si... 38 0.14
UniRef50_A7H7B6 Cluster: Silent information regulator protein Si... 38 0.14
UniRef50_A2DKF0 Cluster: Transcriptional regulator, Sir2 family ... 38 0.14
UniRef50_Q6CAJ8 Cluster: Similar to sp|P53687 Saccharomyces cere... 38 0.14
UniRef50_A4QX96 Cluster: Putative uncharacterized protein; n=2; ... 38 0.14
UniRef50_A3LN35 Cluster: NAD-dependent histone deacetylase SIR2;... 38 0.14
UniRef50_A2QWZ2 Cluster: Function: human SIRT5 belongs to the Si... 38 0.14
UniRef50_Q55PY8 Cluster: Putative uncharacterized protein; n=2; ... 29 0.15
UniRef50_Q4QKL5 Cluster: NAD-dependent deacetylase sirtuin 5; n=... 38 0.19
UniRef50_Q1D737 Cluster: NAD-dependent deacetylase; n=1; Myxococ... 38 0.19
UniRef50_A3WK56 Cluster: SIR2-like regulatory protein, NAD-depen... 38 0.19
UniRef50_A7SK95 Cluster: Predicted protein; n=1; Nematostella ve... 38 0.19
UniRef50_A6XDL2 Cluster: Sirtuin 1; n=2; Schistosoma|Rep: Sirtui... 38 0.19
UniRef50_Q8IXJ6 Cluster: NAD-dependent deacetylase sirtuin-2; n=... 38 0.19
UniRef50_Q6C8C7 Cluster: Similar to DEHA0C01507g Debaryomyces ha... 38 0.25
UniRef50_A6SP88 Cluster: Putative uncharacterized protein; n=2; ... 38 0.25
UniRef50_Q9NTG7 Cluster: NAD-dependent deacetylase sirtuin-3, mi... 38 0.25
UniRef50_UPI0000499DEA Cluster: Sir2 family transcriptional regu... 37 0.33
UniRef50_A2ABY8 Cluster: Sirtuin 7 (Silent mating type informati... 37 0.33
UniRef50_A4A8B4 Cluster: Silent information regulator protein Si... 37 0.33
UniRef50_Q1RL71 Cluster: Zinc finger protein; n=2; Ciona intesti... 37 0.33
UniRef50_A2F9H1 Cluster: Transcriptional regulator, Sir2 family ... 37 0.33
UniRef50_Q882K4 Cluster: NAD-dependent deacetylase 3; n=5; Pseud... 37 0.33
UniRef50_Q1D9X2 Cluster: Sir2 family protein; n=1; Myxococcus xa... 37 0.44
UniRef50_A1ZZG3 Cluster: NAD-dependent deacetylase; n=35; Bacter... 37 0.44
UniRef50_Q89EA6 Cluster: NAD-dependent deacetylase 2; n=9; Prote... 37 0.44
UniRef50_Q9RL35 Cluster: NAD-dependent deacetylase 1; n=8; Actin... 37 0.44
UniRef50_Q07FY7 Cluster: Sirtuin (Silent mating type information... 36 0.58
UniRef50_Q62HT8 Cluster: Transcriptional regulator, Sir2 family;... 36 0.58
UniRef50_A0C6J0 Cluster: Chromosome undetermined scaffold_152, w... 36 0.58
UniRef50_Q6FKU1 Cluster: Similar to sp|P53686 Saccharomyces cere... 36 0.58
UniRef50_Q9I4E1 Cluster: NAD-dependent deacetylase 2; n=6; Pseud... 36 0.58
UniRef50_Q25337 Cluster: NAD-dependent deacetylase SIR2 homolog;... 36 0.77
UniRef50_Q6MJJ2 Cluster: NAD-dependent deacetylase; n=5; Proteob... 36 0.77
UniRef50_UPI00005A356B Cluster: PREDICTED: similar to NAD-depend... 36 1.0
UniRef50_A0JXS0 Cluster: Silent information regulator protein Si... 36 1.0
UniRef50_Q4DP02 Cluster: Silent information regulator 2, putativ... 36 1.0
UniRef50_A2F8N6 Cluster: Transcriptional regulator, Sir2 family ... 36 1.0
UniRef50_Q9I4L0 Cluster: NAD-dependent deacetylase 1; n=10; Bact... 36 1.0
UniRef50_Q2U9Y7 Cluster: Sirtuin 4 and related class II sirtuins... 35 1.4
UniRef50_Q8F3Z6 Cluster: NAD-dependent deacetylase; n=4; Leptosp... 35 1.4
UniRef50_Q8A3H9 Cluster: NAD-dependent deacetylase; n=3; Bactero... 35 1.4
UniRef50_P53686 Cluster: NAD-dependent deacetylase HST2; n=4; Sa... 35 1.4
UniRef50_Q5P3W1 Cluster: NAD-dependent deacetylase 2; n=4; Prote... 35 1.8
UniRef50_A2DKY5 Cluster: Transcriptional regulator, Sir2 family ... 35 1.8
UniRef50_A5DW75 Cluster: Putative uncharacterized protein; n=1; ... 35 1.8
UniRef50_A2QUR5 Cluster: Remark: the H. sapiens SIRT4 belongs to... 35 1.8
UniRef50_Q4APN6 Cluster: Silent information regulator protein Si... 34 2.4
UniRef50_A6Q946 Cluster: Transcriptional regulator, Sir2 family;... 34 2.4
UniRef50_A5B6H9 Cluster: Putative uncharacterized protein; n=3; ... 34 2.4
UniRef50_Q54LF0 Cluster: Ankyrin repeat-containing protein; n=1;... 34 2.4
UniRef50_Q7S223 Cluster: Putative uncharacterized protein NCU059... 34 2.4
UniRef50_A6FYM4 Cluster: Sir2 family protein; n=1; Plesiocystis ... 34 3.1
UniRef50_A5K7T7 Cluster: NAD-dependent deacetylase, putative; n=... 34 3.1
UniRef50_Q2KH01 Cluster: Putative uncharacterized protein; n=2; ... 34 3.1
UniRef50_Q8ZFR1 Cluster: NAD-dependent deacetylase; n=149; cellu... 34 3.1
UniRef50_O25849 Cluster: NAD-dependent deacetylase; n=11; Bacter... 34 3.1
UniRef50_A5WD15 Cluster: Silent information regulator protein Si... 33 4.1
UniRef50_UPI0000E47C29 Cluster: PREDICTED: similar to dermatan/c... 33 5.5
UniRef50_UPI000023DDB4 Cluster: hypothetical protein FG07360.1; ... 33 5.5
UniRef50_UPI000023DCB3 Cluster: hypothetical protein FG05505.1; ... 33 5.5
UniRef50_Q1YSP9 Cluster: NAD-dependent deacetylase; n=1; gamma p... 33 5.5
UniRef50_A0Z2E4 Cluster: NAD-dependent deacetylase; n=1; marine ... 33 5.5
UniRef50_Q7QZ37 Cluster: GLP_464_19573_21615; n=1; Giardia lambl... 33 5.5
UniRef50_A0RQP1 Cluster: General glycosylation pathway protein; ... 33 7.2
UniRef50_Q9XMS2 Cluster: Orf1386; n=2; Alveolata|Rep: Orf1386 - ... 33 7.2
UniRef50_Q6ZMU6 Cluster: CDNA FLJ16662 fis, clone TESTI4046240, ... 33 7.2
UniRef50_Q4WET3 Cluster: SIR2 family histone deacetylase, putati... 33 7.2
UniRef50_Q3V7G9 Cluster: Putative cobalamin biosynthetic protein... 32 9.5
UniRef50_Q1RPJ3 Cluster: Putative uncharacterized protein; n=1; ... 32 9.5
UniRef50_Q17JQ3 Cluster: Mitochondrial ribosomal protein, S34, p... 32 9.5
UniRef50_Q4P1X1 Cluster: Putative uncharacterized protein; n=1; ... 32 9.5
UniRef50_Q8R104 Cluster: NAD-dependent deacetylase sirtuin-3; n=... 32 9.5
UniRef50_Q9RYD4 Cluster: NAD-dependent deacetylase; n=4; Deinoco... 32 9.5
>UniRef50_Q9VH08 Cluster: CG6284-PA; n=9; Eumetazoa|Rep: CG6284-PA -
Drosophila melanogaster (Fruit fly)
Length = 317
Score = 184 bits (448), Expect = 2e-45
Identities = 83/129 (64%), Positives = 101/129 (78%)
Frame = +1
Query: 232 MSCNYAEGLSPYENKGILGVPEKFDSNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAG 411
MSCNYA+GLS Y+NKGILG PE FDS++ + +KC LA+L+K S H+V+HTGAGISTSAG
Sbjct: 1 MSCNYADGLSAYDNKGILGAPESFDSDEVVAEKCQELAELIKKSGHVVLHTGAGISTSAG 60
Query: 412 IPDFRGPNGVWTLEKEGKKPTINVSFADAQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHL 591
IPDFRGP GVWTLE++G+KP NVSF +A+PTKTHM +SQNIDGLHL
Sbjct: 61 IPDFRGPKGVWTLEEKGEKPDFNVSFDEARPTKTHMAIIALIESGYVQYVISQNIDGLHL 120
Query: 592 KSGVPRKFL 618
KSG+ RK+L
Sbjct: 121 KSGLDRKYL 129
>UniRef50_Q8N6T7-2 Cluster: Isoform 2 of Q8N6T7 ; n=5;
Catarrhini|Rep: Isoform 2 of Q8N6T7 - Homo sapiens
(Human)
Length = 328
Score = 143 bits (347), Expect = 3e-33
Identities = 67/126 (53%), Positives = 86/126 (68%)
Frame = +1
Query: 232 MSCNYAEGLSPYENKGILGVPEKFDSNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAG 411
MS NYA GLSPY +KG G+PE FD ++L +K LA+LV S +V HTGAGIST++G
Sbjct: 1 MSVNYAAGLSPYADKGKCGLPEIFDPPEELERKVWELARLVWQSSSVVFHTGAGISTASG 60
Query: 412 IPDFRGPNGVWTLEKEGKKPTINVSFADAQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHL 591
IPDFRGP+GVWT+E+ G P + +F A+PT+THM VSQN+DGLH+
Sbjct: 61 IPDFRGPHGVWTMEERGLAPKFDTTFESARPTQTHMALVQLERVGLLRFLVSQNVDGLHV 120
Query: 592 KSGVPR 609
+SG PR
Sbjct: 121 RSGFPR 126
>UniRef50_Q8N6T7 Cluster: Mono-ADP-ribosyltransferase sirtuin-6;
n=22; Euteleostomi|Rep: Mono-ADP-ribosyltransferase
sirtuin-6 - Homo sapiens (Human)
Length = 355
Score = 143 bits (347), Expect = 3e-33
Identities = 67/126 (53%), Positives = 86/126 (68%)
Frame = +1
Query: 232 MSCNYAEGLSPYENKGILGVPEKFDSNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAG 411
MS NYA GLSPY +KG G+PE FD ++L +K LA+LV S +V HTGAGIST++G
Sbjct: 1 MSVNYAAGLSPYADKGKCGLPEIFDPPEELERKVWELARLVWQSSSVVFHTGAGISTASG 60
Query: 412 IPDFRGPNGVWTLEKEGKKPTINVSFADAQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHL 591
IPDFRGP+GVWT+E+ G P + +F A+PT+THM VSQN+DGLH+
Sbjct: 61 IPDFRGPHGVWTMEERGLAPKFDTTFESARPTQTHMALVQLERVGLLRFLVSQNVDGLHV 120
Query: 592 KSGVPR 609
+SG PR
Sbjct: 121 RSGFPR 126
>UniRef50_Q9FE17 Cluster: Sir2-like protein; n=9; Magnoliophyta|Rep:
Sir2-like protein - Arabidopsis thaliana (Mouse-ear
cress)
Length = 473
Score = 130 bits (315), Expect = 2e-29
Identities = 66/130 (50%), Positives = 85/130 (65%), Gaps = 1/130 (0%)
Frame = +1
Query: 232 MSCNYAEGLSPYENKGILGVPEKFDSNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAG 411
MS YAE LS E+ G +G+ E FD + L K LA+L++ SKH+VV TGAGISTS G
Sbjct: 1 MSLGYAEKLSFIEDVGQVGMAEFFDPSHLLQCKIEELAKLIQKSKHLVVFTGAGISTSCG 60
Query: 412 IPDFRGPNGVWTLEKEGKK-PTINVSFADAQPTKTHMXXXXXXXXXXXXXXVSQNIDGLH 588
IPDFRGP G+WTL++EGK P ++ F A P+ THM +SQN+DGLH
Sbjct: 61 IPDFRGPKGIWTLQREGKDLPKASLPFHRAMPSMTHMALVELERAGILKFVISQNVDGLH 120
Query: 589 LKSGVPRKFL 618
L+SG+PR+ L
Sbjct: 121 LRSGIPREKL 130
>UniRef50_A5AF92 Cluster: Putative uncharacterized protein; n=1;
Vitis vinifera|Rep: Putative uncharacterized protein -
Vitis vinifera (Grape)
Length = 343
Score = 109 bits (262), Expect = 5e-23
Identities = 51/98 (52%), Positives = 67/98 (68%), Gaps = 1/98 (1%)
Frame = +1
Query: 319 LNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKK-PTINVSFAD 495
+++K LA +++ SKH+VV TGAGISTS GIPDFRGP G+WTL++EGK P ++ F
Sbjct: 61 MHKKIERLAVMLRKSKHLVVFTGAGISTSCGIPDFRGPKGIWTLQREGKALPQASLPFHR 120
Query: 496 AQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSGVPR 609
A P+ THM +SQNIDGLHL+SG+PR
Sbjct: 121 AMPSMTHMALVELEKAGILKFVISQNIDGLHLRSGIPR 158
>UniRef50_Q7SB01 Cluster: Putative uncharacterized protein
NCU07624.1; n=1; Neurospora crassa|Rep: Putative
uncharacterized protein NCU07624.1 - Neurospora crassa
Length = 437
Score = 106 bits (254), Expect = 5e-22
Identities = 51/104 (49%), Positives = 68/104 (65%), Gaps = 1/104 (0%)
Frame = +1
Query: 295 EKFDSNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKPT 474
E F++ + +++K +LA L++ SKH VV TGAG+STSAGIPDFRGP GVWTL +G++ T
Sbjct: 12 EMFEAPEVIDRKAKVLADLIRKSKHFVVFTGAGVSTSAGIPDFRGPEGVWTLMAQGRQAT 71
Query: 475 -INVSFADAQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSGV 603
+V A PTKTHM +SQN DGLH +SG+
Sbjct: 72 KKSVDVLQAIPTKTHMALVELQERGILKGLISQNCDGLHRRSGI 115
>UniRef50_UPI0000D573CE Cluster: PREDICTED: similar to CG11305-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG11305-PA - Tribolium castaneum
Length = 627
Score = 103 bits (248), Expect = 3e-21
Identities = 51/109 (46%), Positives = 72/109 (66%), Gaps = 1/109 (0%)
Frame = +1
Query: 295 EKFDSNDK-LNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKP 471
E+F+ + L +KC++LAQ + ++H+VV+TGAGIST+A IPD+RGPNG+WT ++GK
Sbjct: 96 EEFEEPPEVLKEKCLILAQAIAQAQHLVVYTGAGISTAAKIPDYRGPNGIWTRLQQGKDI 155
Query: 472 TINVSFADAQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSGVPRKFL 618
+ + A+PT THM VSQN DGLHL+SG+PR L
Sbjct: 156 GAH-DLSMAEPTYTHMALSELYRNKILKYVVSQNCDGLHLRSGLPRTAL 203
>UniRef50_Q9NRC8 Cluster: NAD-dependent deacetylase sirtuin-7; n=24;
Eumetazoa|Rep: NAD-dependent deacetylase sirtuin-7 -
Homo sapiens (Human)
Length = 400
Score = 101 bits (243), Expect = 1e-20
Identities = 50/105 (47%), Positives = 69/105 (65%)
Frame = +1
Query: 295 EKFDSNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKPT 474
E D ++L K LA V+++K++VV+TGAGIST+A IPD+RGPNGVWTL ++G+ +
Sbjct: 77 EVCDDPEELRGKVRELASAVRNAKYLVVYTGAGISTAASIPDYRGPNGVWTLLQKGRSVS 136
Query: 475 INVSFADAQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSGVPR 609
++A+PT THM VSQN DGLHL+SG+PR
Sbjct: 137 A-ADLSEAEPTLTHMSITRLHEQKLVQHVVSQNCDGLHLRSGLPR 180
>UniRef50_Q175I4 Cluster: Chromatin regulatory protein sir2; n=3;
Coelomata|Rep: Chromatin regulatory protein sir2 - Aedes
aegypti (Yellowfever mosquito)
Length = 720
Score = 97.5 bits (232), Expect = 2e-19
Identities = 51/106 (48%), Positives = 66/106 (62%), Gaps = 1/106 (0%)
Frame = +1
Query: 295 EKFDSNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKK-P 471
EK D +++ K + LAQ + S H++V+TGAGISTSA IPD+RG G+WTL +GK
Sbjct: 58 EKEDEPEEIETKALRLAQAIARSNHLMVYTGAGISTSAKIPDYRGSQGIWTLLAQGKDIG 117
Query: 472 TINVSFADAQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSGVPR 609
++S AD PT THM VSQN DGLHL+SG+PR
Sbjct: 118 EYDLSLAD--PTYTHMALSELHRRGILKHVVSQNCDGLHLRSGLPR 161
>UniRef50_UPI00015B56BB Cluster: PREDICTED: similar to
ENSANGP00000025716; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ENSANGP00000025716 - Nasonia
vitripennis
Length = 581
Score = 97.1 bits (231), Expect = 3e-19
Identities = 48/105 (45%), Positives = 64/105 (60%)
Frame = +1
Query: 304 DSNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKPTINV 483
D+ + L +KC+ LA + + + V+TGAGIST+A IPD+RG NGVWT ++G K N
Sbjct: 91 DAPEILEEKCIRLAAAISRATSLAVYTGAGISTAASIPDYRGTNGVWTRLQQG-KDIGNH 149
Query: 484 SFADAQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSGVPRKFL 618
+ A+PT THM VSQN DGLHL+SG+PR L
Sbjct: 150 DLSQAEPTITHMALYALYKARMLKHIVSQNCDGLHLRSGIPRPLL 194
>UniRef50_Q9VAQ1 Cluster: CG11305-PA; n=8; Coelomata|Rep: CG11305-PA
- Drosophila melanogaster (Fruit fly)
Length = 771
Score = 91.1 bits (216), Expect = 2e-17
Identities = 47/110 (42%), Positives = 65/110 (59%)
Frame = +1
Query: 289 VPEKFDSNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKK 468
V E+ D+ + K LA ++ +KH+V +TGAGIST+A IPD+RG G+WTL ++G+
Sbjct: 99 VVEREDAPHVIEAKVEQLANIISQAKHLVCYTGAGISTAALIPDYRGSQGIWTLLQKGQD 158
Query: 469 PTINVSFADAQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSGVPRKFL 618
+ + A PT THM VSQN DGLHL+SG+PR L
Sbjct: 159 IGEH-DLSSANPTYTHMALYELHRRRLLHHVVSQNCDGLHLRSGLPRNSL 207
>UniRef50_A5K3P4 Cluster: Putative uncharacterized protein; n=1;
Plasmodium vivax|Rep: Putative uncharacterized protein -
Plasmodium vivax
Length = 1259
Score = 86.2 bits (204), Expect = 6e-16
Identities = 41/75 (54%), Positives = 53/75 (70%), Gaps = 1/75 (1%)
Frame = +1
Query: 232 MSC-NYAEGLSPYENKGILGVPEKFDSNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSA 408
MSC NYA LS ENKG LG E F+ +++ +K L + ++ S+HIVVH GAGISTS+
Sbjct: 1 MSCMNYARRLSKNENKGPLGEKEYFEDSEEEKRKIKKLIEKIRTSEHIVVHAGAGISTSS 60
Query: 409 GIPDFRGPNGVWTLE 453
G+ DFRGP G+WT E
Sbjct: 61 GLQDFRGPTGIWTNE 75
>UniRef50_Q4UH74 Cluster: Sir2-like histone deacetylase, putative;
n=2; Theileria|Rep: Sir2-like histone deacetylase,
putative - Theileria annulata
Length = 928
Score = 83.8 bits (198), Expect = 3e-15
Identities = 35/70 (50%), Positives = 50/70 (71%)
Frame = +1
Query: 241 NYAEGLSPYENKGILGVPEKFDSNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPD 420
NYA L NKG LG+ E FD+N ++ +K LL + + S + ++HTGAG+ST +GIPD
Sbjct: 7 NYASRLKKNNNKGPLGLDELFDTNKQVTKKVNLLYEYLSKSNNTIIHTGAGVSTGSGIPD 66
Query: 421 FRGPNGVWTL 450
FRGP+G+WT+
Sbjct: 67 FRGPSGIWTV 76
Score = 33.1 bits (72), Expect = 5.5
Identities = 14/42 (33%), Positives = 22/42 (52%)
Frame = +1
Query: 481 VSFADAQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSGVP 606
V F A P+++H+ ++QN+DGLH SG+P
Sbjct: 182 VEFILALPSESHLCLLELLRRKKIRYIITQNVDGLHAVSGIP 223
>UniRef50_Q7RP35 Cluster: Sir2-like protein; n=5; Plasmodium
(Vinckeia)|Rep: Sir2-like protein - Plasmodium yoelii
yoelii
Length = 1159
Score = 82.2 bits (194), Expect = 9e-15
Identities = 39/75 (52%), Positives = 53/75 (70%), Gaps = 1/75 (1%)
Frame = +1
Query: 232 MSCNY-AEGLSPYENKGILGVPEKFDSNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSA 408
MSC Y A LS ENKG LG E F+ ++ +K +L + ++ S++IVVH+GAGISTS+
Sbjct: 1 MSCMYYASRLSKNENKGPLGEKEYFEDEEEEKEKIKVLIEKIRTSEYIVVHSGAGISTSS 60
Query: 409 GIPDFRGPNGVWTLE 453
G+ DFRGP G+WT E
Sbjct: 61 GLQDFRGPTGIWTNE 75
>UniRef50_Q1MT39 Cluster: Novel protein similar to vertebratesirtuin
(Silent mating type information regulation 2 homolog) 7;
n=2; Danio rerio|Rep: Novel protein similar to
vertebratesirtuin (Silent mating type information
regulation 2 homolog) 7 - Danio rerio (Zebrafish)
(Brachydanio rerio)
Length = 376
Score = 81.4 bits (192), Expect = 2e-14
Identities = 37/75 (49%), Positives = 53/75 (70%)
Frame = +1
Query: 295 EKFDSNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKPT 474
E FD + L K LA+ V+ +KH+V++TGAGIST+A IPD+RGPNGVWT ++G+ +
Sbjct: 74 EVFDDAENLKTKVKQLAEAVQRAKHLVIYTGAGISTAASIPDYRGPNGVWTQLQKGRSVS 133
Query: 475 INVSFADAQPTKTHM 519
+ + A+PT THM
Sbjct: 134 TS-DLSQAEPTLTHM 147
>UniRef50_Q8N6T7-3 Cluster: Isoform 3 of Q8N6T7 ; n=2;
Catarrhini|Rep: Isoform 3 of Q8N6T7 - Homo sapiens
(Human)
Length = 187
Score = 81.0 bits (191), Expect = 2e-14
Identities = 39/65 (60%), Positives = 48/65 (73%)
Frame = +1
Query: 232 MSCNYAEGLSPYENKGILGVPEKFDSNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAG 411
MS NYA GLSPY +KG G+PE FD ++L +K LA+LV S +V HTGAGIST++G
Sbjct: 1 MSVNYAAGLSPYADKGKCGLPEIFDPPEELERKVWELARLVWQSSSVVFHTGAGISTASG 60
Query: 412 IPDFR 426
IPDFR
Sbjct: 61 IPDFR 65
>UniRef50_Q8IKW2 Cluster: Putative uncharacterized protein; n=1;
Plasmodium falciparum 3D7|Rep: Putative uncharacterized
protein - Plasmodium falciparum (isolate 3D7)
Length = 1304
Score = 80.2 bits (189), Expect = 4e-14
Identities = 39/75 (52%), Positives = 52/75 (69%), Gaps = 1/75 (1%)
Frame = +1
Query: 232 MSC-NYAEGLSPYENKGILGVPEKFDSNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSA 408
MSC NYA LS E KG LG E F+ ++ +K L + ++ S++IVVH+GAGISTS+
Sbjct: 1 MSCMNYASRLSKNEYKGPLGEEEFFEDTEEEKKKVKELIEKIRSSEYIVVHSGAGISTSS 60
Query: 409 GIPDFRGPNGVWTLE 453
G+ DFRGP G+WT E
Sbjct: 61 GLQDFRGPTGIWTNE 75
>UniRef50_UPI0000E49846 Cluster: PREDICTED: similar to Sirtuin
(silent mating type information regulation 2 homolog) 6
(S. cerevisiae); n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to Sirtuin (silent mating type
information regulation 2 homolog) 6 (S. cerevisiae) -
Strongylocentrotus purpuratus
Length = 521
Score = 78.6 bits (185), Expect = 1e-13
Identities = 35/62 (56%), Positives = 41/62 (66%)
Frame = +1
Query: 424 RGPNGVWTLEKEGKKPTINVSFADAQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSGV 603
RGP GVWTLEK+GKKP NV+F A+PT THM +SQNIDGLHL+SG
Sbjct: 11 RGPKGVWTLEKQGKKPEANVTFDTAKPTATHMALVELERRGKLQYLISQNIDGLHLRSGF 70
Query: 604 PR 609
P+
Sbjct: 71 PK 72
>UniRef50_A7AWG1 Cluster: Transcriptional regulator, Sir2 family
domain containing protein; n=2; Babesia bovis|Rep:
Transcriptional regulator, Sir2 family domain containing
protein - Babesia bovis
Length = 656
Score = 78.6 bits (185), Expect = 1e-13
Identities = 52/147 (35%), Positives = 77/147 (52%), Gaps = 27/147 (18%)
Frame = +1
Query: 244 YAEGLSPYENKGILGVPEKFDSNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDF 423
YA L P +NKG G + FD+ +++K +L+ +K++V+H+GAG+ST+AGIPDF
Sbjct: 8 YANQLRPNDNKGPCGGVQLFDNPADISKKFKQTVELLTRAKNVVLHSGAGMSTAAGIPDF 67
Query: 424 RGPNGVWTL-------EKEGK--------KPTIN------------VSFADAQPTKTHMX 522
RGP+GVWT+ K+ K K T N V F+ A P++ H+
Sbjct: 68 RGPSGVWTVMSHKRVGNKKRKMTDGDCTVKDTSNTCVEFGTTKLEPVEFSHALPSEAHLA 127
Query: 523 XXXXXXXXXXXXXVSQNIDGLHLKSGV 603
++QNIDGLH SG+
Sbjct: 128 TLALLRAGYIRTVITQNIDGLHAISGM 154
>UniRef50_Q22KA8 Cluster: Transcriptional regulator, Sir2 family
protein; n=3; Tetrahymena thermophila SB210|Rep:
Transcriptional regulator, Sir2 family protein -
Tetrahymena thermophila SB210
Length = 386
Score = 77.4 bits (182), Expect = 3e-13
Identities = 50/113 (44%), Positives = 61/113 (53%), Gaps = 11/113 (9%)
Frame = +1
Query: 295 EKFDSNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFR-GPN-------GVW-- 444
E FDS + L K LA ++K S H V TGAGISTSAGI DFR G N G+W
Sbjct: 13 EYFDSPELLEAKVTQLADMIKQSNHFVCFTGAGISTSAGIADFRSGVNTVLKTGPGLWEK 72
Query: 445 TLEKEGKKPTIN-VSFADAQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSG 600
+K G +P + V + A PTK+HM +SQNIDGLH +SG
Sbjct: 73 MAQKVGNQPKKHKVIMSRAVPTKSHMALVKLNQEGILKYLISQNIDGLHRRSG 125
>UniRef50_UPI00006CB0CC Cluster: transcriptional regulator, Sir2
family protein; n=1; Tetrahymena thermophila SB210|Rep:
transcriptional regulator, Sir2 family protein -
Tetrahymena thermophila SB210
Length = 442
Score = 70.1 bits (164), Expect = 4e-11
Identities = 46/129 (35%), Positives = 70/129 (54%), Gaps = 15/129 (11%)
Frame = +1
Query: 271 NKGILGVPEKFDSNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFR-GPN---- 435
N + E DS ++++ K L +L++ SK+ V+ TGAG+ST++GIPD+R G N
Sbjct: 38 NPRLKDTQEHQDSPEQIDTKVNQLIELLQKSKNAVILTGAGVSTASGIPDYRSGANTILK 97
Query: 436 ---GVWTLEKEGK-------KPTINVSFADAQPTKTHMXXXXXXXXXXXXXXVSQNIDGL 585
G W LE+ K KP I ++ +A P+ THM ++QN+D L
Sbjct: 98 TGPGKWELEENKKKFLEEKGKPQIILAI-NAFPSPTHMAISKLYKENLIKSVITQNVDNL 156
Query: 586 HLKSGVPRK 612
H +SG+PRK
Sbjct: 157 HHQSGIPRK 165
>UniRef50_Q29QS4 Cluster: IP11347p; n=1; Drosophila
melanogaster|Rep: IP11347p - Drosophila melanogaster
(Fruit fly)
Length = 98
Score = 69.3 bits (162), Expect = 7e-11
Identities = 30/47 (63%), Positives = 36/47 (76%)
Frame = -3
Query: 518 IWVFVGCASANDTLMVGFLPSFSKVHTPFGPLKSGIPAEVLMPAPVW 378
+WV VG AS+ +TL GF P S+V TP GP KSGIPA+VL+PAPVW
Sbjct: 4 MWVLVGLASSKETLKSGFSPFSSRVQTPLGPRKSGIPADVLIPAPVW 50
>UniRef50_Q95Q89 Cluster: Yeast sir related protein 2.4; n=2;
Caenorhabditis|Rep: Yeast sir related protein 2.4 -
Caenorhabditis elegans
Length = 299
Score = 67.3 bits (157), Expect = 3e-10
Identities = 35/87 (40%), Positives = 46/87 (52%)
Frame = +1
Query: 346 QLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKPTINVSFADAQPTKTHMXX 525
Q + K I V GAG+ST + +PDFRG GVWTL+ EGK V F A+P +H
Sbjct: 50 QAKQTGKPIFVLIGAGVSTGSKLPDFRGKQGVWTLQAEGKHAE-GVDFQVARPGVSHKSI 108
Query: 526 XXXXXXXXXXXXVSQNIDGLHLKSGVP 606
++QN+DGL K G+P
Sbjct: 109 LALHKAGYIKTIITQNVDGLDRKVGIP 135
>UniRef50_UPI000049979A Cluster: Sir2 family transcriptional
regulator; n=1; Entamoeba histolytica HM-1:IMSS|Rep:
Sir2 family transcriptional regulator - Entamoeba
histolytica HM-1:IMSS
Length = 319
Score = 58.8 bits (136), Expect = 1e-07
Identities = 38/115 (33%), Positives = 54/115 (46%), Gaps = 17/115 (14%)
Frame = +1
Query: 307 SNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW---------TLEKE 459
S +++ C LA+++ SK +VV TGAGIS SAGIPDFR NG+W + E
Sbjct: 9 SEEEIEFSCKSLARIISRSKRLVVLTGAGISVSAGIPDFRSRNGMWKRYEPKVYASYENF 68
Query: 460 GKKPTINVSFAD--------AQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSG 600
KP + + +PTK H ++QN+D LH +G
Sbjct: 69 VNKPEMFWKMCNELRNCTEGKKPTKAHFALRKLEEIGKLEEIITQNVDNLHQLAG 123
>UniRef50_Q2LSF2 Cluster: Sir2 family of NAD+-dependent deacetylase;
n=2; Syntrophus aciditrophicus SB|Rep: Sir2 family of
NAD+-dependent deacetylase - Syntrophus aciditrophicus
(strain SB)
Length = 271
Score = 57.6 bits (133), Expect = 2e-07
Identities = 37/121 (30%), Positives = 57/121 (47%), Gaps = 19/121 (15%)
Frame = +1
Query: 307 SNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW-------------- 444
S+ + +K +A ++ + +VV TGAG+ST +GIPDFR P G+W
Sbjct: 7 SDREFMEKIDAVADMIWMAGRVVVFTGAGVSTESGIPDFRSPGGLWDRFDPDDFTIGKFL 66
Query: 445 ----TLEKEGKKPTINVSFADAQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSG-VPR 609
T K+ + + A+AQP + H+ ++QNID LH K+G P
Sbjct: 67 RSAQTRRKQWRILIAGGALAEAQPNRAHLAVAELEKIGKLNCVITQNIDNLHQKAGNAPE 126
Query: 610 K 612
K
Sbjct: 127 K 127
>UniRef50_A6DC77 Cluster: Silent information regulator protein Sir2;
n=1; Caminibacter mediatlanticus TB-2|Rep: Silent
information regulator protein Sir2 - Caminibacter
mediatlanticus TB-2
Length = 243
Score = 57.6 bits (133), Expect = 2e-07
Identities = 35/103 (33%), Positives = 50/103 (48%), Gaps = 17/103 (16%)
Frame = +1
Query: 343 AQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTL--------------EKEGKKPTIN 480
A+++KDSK++V TGAGIS +GIP FRGP G+W+ KE K
Sbjct: 8 AEIIKDSKNLVAFTGAGISVESGIPTFRGPTGLWSKYDPKILDIDFFIQNPKESWKYIKE 67
Query: 481 VSF---ADAQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSG 600
+ + D +P + H ++QNID LH K+G
Sbjct: 68 IFYDYMQDIKPNEAHYFLADLEKKGILKAVITQNIDNLHQKAG 110
>UniRef50_A4M603 Cluster: Silent information regulator protein Sir2;
n=1; Petrotoga mobilis SJ95|Rep: Silent information
regulator protein Sir2 - Petrotoga mobilis SJ95
Length = 256
Score = 56.8 bits (131), Expect = 4e-07
Identities = 39/106 (36%), Positives = 54/106 (50%), Gaps = 20/106 (18%)
Frame = +1
Query: 343 AQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWT---LEKEGK---------KPTINVS 486
A+L+ +S I V +GAG+ST+AGIPDFRGPNG++T +E + P++
Sbjct: 9 AELIYNSNSIAVLSGAGMSTNAGIPDFRGPNGIYTKANIENPERIFDLDYFYLDPSLFYK 68
Query: 487 F--------ADAQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSG 600
F A+PT TH V+QNID LH K+G
Sbjct: 69 FHKKFLEYITKAEPTFTHKFLVQLEKEGKLKGIVTQNIDSLHQKAG 114
>UniRef50_A3ZMQ7 Cluster: Sir2 family, possible ADP
ribosyltransferase; n=1; Blastopirellula marina DSM
3645|Rep: Sir2 family, possible ADP ribosyltransferase -
Blastopirellula marina DSM 3645
Length = 252
Score = 56.8 bits (131), Expect = 4e-07
Identities = 37/105 (35%), Positives = 50/105 (47%), Gaps = 17/105 (16%)
Frame = +1
Query: 337 LLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWT-----------------LEKEGK 465
L+A+ + +S+ V+ TGAGIST +GIPDFR P GVWT E +
Sbjct: 9 LVARWLAESESTVLFTGAGISTESGIPDFRSPGGVWTKYRTIYFDEFRQSAEARREYWRQ 68
Query: 466 KPTINVSFADAQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSG 600
K +V F+ A P H ++QNIDGLH +G
Sbjct: 69 KSEAHVEFSAAAPNAGHQILAAWEAHGVARGLITQNIDGLHQIAG 113
>UniRef50_Q3F1F4 Cluster: SIR2 family protein; n=1; Bacillus
thuringiensis serovar israelensis ATCC 35646|Rep: SIR2
family protein - Bacillus thuringiensis serovar
israelensis ATCC 35646
Length = 241
Score = 56.4 bits (130), Expect = 5e-07
Identities = 36/101 (35%), Positives = 48/101 (47%), Gaps = 15/101 (14%)
Frame = +1
Query: 343 AQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGK--------KPTINVSFAD- 495
A+L+K S HIVV TGAGIST +G+PD+R G+W +K + KP FAD
Sbjct: 6 AELIKKSNHIVVLTGAGISTDSGLPDYRSNGGLWDGKKPEEISHFSAVGKPEFVKFFADR 65
Query: 496 ------AQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSG 600
+P K H ++QNID H +G
Sbjct: 66 MNDISNCKPNKAHEILAKWEEQGKVKSVITQNIDSYHKDAG 106
>UniRef50_Q89LY4 Cluster: NAD-dependent deacetylase 1; n=12;
Proteobacteria|Rep: NAD-dependent deacetylase 1 -
Bradyrhizobium japonicum
Length = 254
Score = 56.4 bits (130), Expect = 5e-07
Identities = 35/104 (33%), Positives = 50/104 (48%), Gaps = 17/104 (16%)
Frame = +1
Query: 340 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEK----EG-------------KK 468
L ++ ++K IV TGAGIST GIPDFR P G+WT + +G ++
Sbjct: 15 LGDMIAEAKTIVPFTGAGISTECGIPDFRSPGGIWTRNRPIPFDGFVASQEARDESWRRR 74
Query: 469 PTINVSFADAQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSG 600
+ +FA A+P + H ++QNID LH SG
Sbjct: 75 FAMEETFAAARPGRGHRALASLYRAGKVPAVITQNIDNLHQASG 118
>UniRef50_Q974M6 Cluster: NAD-dependent deacetylase; n=8;
Thermoprotei|Rep: NAD-dependent deacetylase - Sulfolobus
tokodaii
Length = 250
Score = 56.0 bits (129), Expect = 7e-07
Identities = 37/107 (34%), Positives = 50/107 (46%), Gaps = 16/107 (14%)
Frame = +1
Query: 328 KCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW--------TLEKEGKKPTINV 483
+C + L+ S + + TGAGIST++GIPDFRGPNG+W T+E K P
Sbjct: 2 ECDKVGDLLLTSTYAIAFTGAGISTASGIPDFRGPNGLWKKYSPELATIEYFKKDPKGFW 61
Query: 484 SF--------ADAQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSG 600
F A P + H ++QNIDGLH +G
Sbjct: 62 EFYRLRMRGLFTALPNRAHYALAELEKMGLIRAIITQNIDGLHQLAG 108
>UniRef50_Q8ZT00 Cluster: NAD-dependent deacetylase 2; n=2; cellular
organisms|Rep: NAD-dependent deacetylase 2 - Pyrobaculum
aerophilum
Length = 249
Score = 54.0 bits (124), Expect = 3e-06
Identities = 33/104 (31%), Positives = 49/104 (47%), Gaps = 17/104 (16%)
Frame = +1
Query: 340 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW---------TLEKEGKKPTI----- 477
+A L+ S+H VV TGAGIS +G+P FRGP G+W T E + P +
Sbjct: 3 VADLLASSRHCVVFTGAGISAESGVPTFRGPGGLWERYKPEELATPEAFARDPALVWRWY 62
Query: 478 ---NVSFADAQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSG 600
+A+P+ H ++QN+DGLH ++G
Sbjct: 63 KWRQEVIYNARPSPGHYAIAELEAMGVVRGVITQNVDGLHQRAG 106
>UniRef50_UPI000049971A Cluster: Sir2 family transcriptional
regulator; n=1; Entamoeba histolytica HM-1:IMSS|Rep:
Sir2 family transcriptional regulator - Entamoeba
histolytica HM-1:IMSS
Length = 285
Score = 52.8 bits (121), Expect = 6e-06
Identities = 34/112 (30%), Positives = 53/112 (47%), Gaps = 15/112 (13%)
Frame = +1
Query: 310 NDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW------------TLE 453
+D ++ ++A+ ++ SK++ V TGAGIS +GIPDFR NG+W +
Sbjct: 18 DDSIDIDIEMIARSMEKSKNVTVLTGAGISVESGIPDFRSSNGLWKRYDPSVYGSYSNFK 77
Query: 454 KEGK---KPTINVSFADAQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSG 600
K + K T + A P H V+QN+DGLH ++G
Sbjct: 78 KHPELFWKMTEEIHKITAYPNHVHEALAELEKIGVVKTIVTQNVDGLHQQAG 129
>UniRef50_Q0AY57 Cluster: Regulatory protein, sir2 family; n=1;
Syntrophomonas wolfei subsp. wolfei str. Goettingen|Rep:
Regulatory protein, sir2 family - Syntrophomonas wolfei
subsp. wolfei (strain Goettingen)
Length = 253
Score = 51.6 bits (118), Expect = 1e-05
Identities = 36/106 (33%), Positives = 48/106 (45%), Gaps = 19/106 (17%)
Frame = +1
Query: 340 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGK-KPTINVS---------- 486
+ +++ S + VV TGAGIST AGIPDFRGP G++ E + IN+
Sbjct: 8 VVEILDRSHNTVVVTGAGISTEAGIPDFRGPEGIYRKLGENRVMKIINIDFFRNNPLEFY 67
Query: 487 --------FADAQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSG 600
F +P K H V+QNID LH K+G
Sbjct: 68 KFYRQYFIFPPVEPGKAHQVLAEMEKAGIIKAIVTQNIDNLHQKAG 113
>UniRef50_A6P1S7 Cluster: Putative uncharacterized protein; n=2;
Bacteria|Rep: Putative uncharacterized protein -
Bacteroides capillosus ATCC 29799
Length = 262
Score = 51.6 bits (118), Expect = 1e-05
Identities = 35/113 (30%), Positives = 50/113 (44%), Gaps = 19/113 (16%)
Frame = +1
Query: 319 LNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKPTI------- 477
+ + LL + + +S IV GAG+ST +GIPDFR +G++ + + TI
Sbjct: 21 MEENRALLQRWIDESSRIVFFGGAGVSTESGIPDFRSVDGLYNQQYDYPPETILSHTFYE 80
Query: 478 ------------NVSFADAQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSG 600
+ F DAQP H V+QNIDGLH K+G
Sbjct: 81 ARPEEFFRFYRNKMLFPDAQPNAAHKKLAELEQAGKLTAMVTQNIDGLHQKAG 133
>UniRef50_Q8R984 Cluster: NAD-dependent deacetylase 2; n=1;
Thermoanaerobacter tengcongensis|Rep: NAD-dependent
deacetylase 2 - Thermoanaerobacter tengcongensis
Length = 250
Score = 50.4 bits (115), Expect = 3e-05
Identities = 36/104 (34%), Positives = 48/104 (46%), Gaps = 18/104 (17%)
Frame = +1
Query: 343 AQLVKDSKHIVVHTGAGISTSAGIPDFRGP-NGVW----TLEKEGKKPTIN--------- 480
A+L+K S+ +V TGAGIST +GIPDFR P G+W E K N
Sbjct: 14 AELIKSSQKTMVLTGAGISTESGIPDFRSPGTGLWENMDPTEVLSTKVLFNSPEEFYRVG 73
Query: 481 ----VSFADAQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSG 600
S +A+P + H ++QNID LH K+G
Sbjct: 74 FKILSSMRNAEPNEAHYILSEMEKEGIIAGVITQNIDNLHQKAG 117
>UniRef50_Q3A6W7 Cluster: NAD-dependent protein deacetylases, SIR2
family; n=2; Pelobacter|Rep: NAD-dependent protein
deacetylases, SIR2 family - Pelobacter carbinolicus
(strain DSM 2380 / Gra Bd 1)
Length = 278
Score = 50.0 bits (114), Expect = 4e-05
Identities = 20/54 (37%), Positives = 35/54 (64%)
Frame = +1
Query: 343 AQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKPTINVSFADAQP 504
A +++ S+ +V +GAGIST+AGIPDFRGP G++ + + ++ + +P
Sbjct: 26 ADMIRRSRCVVTLSGAGISTAAGIPDFRGPQGLYVTRRYDPEKVFDIDWFHREP 79
>UniRef50_A0NQ49 Cluster: Silent information regulator protein Sir2;
n=1; Stappia aggregata IAM 12614|Rep: Silent information
regulator protein Sir2 - Stappia aggregata IAM 12614
Length = 260
Score = 50.0 bits (114), Expect = 4e-05
Identities = 33/109 (30%), Positives = 46/109 (42%), Gaps = 24/109 (22%)
Frame = +1
Query: 364 KHIVVHTGAGISTSAGIPDFRGPNGVWT------------------------LEKEGKKP 471
+ IV TGAGIST +GIPDFR P G+W+ LE ++
Sbjct: 23 RQIVALTGAGISTESGIPDFRSPGGIWSKRQPVQYQDFVDDEDSRLEDWDRRLEDWDRRS 82
Query: 472 TINVSFADAQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSGVPRKFL 618
+ F A+P H ++QN+DGLH ++G P L
Sbjct: 83 EMMDYFCKAEPNAAHFALTTLARSGKLVCLITQNVDGLHQRAGFPDDLL 131
>UniRef50_Q54GV7 Cluster: NAD(+)-dependent deacetylase, silent
information regulator protein (Sir2) family protein;
n=1; Dictyostelium discoideum AX4|Rep: NAD(+)-dependent
deacetylase, silent information regulator protein (Sir2)
family protein - Dictyostelium discoideum AX4
Length = 542
Score = 50.0 bits (114), Expect = 4e-05
Identities = 24/45 (53%), Positives = 32/45 (71%), Gaps = 1/45 (2%)
Frame = +1
Query: 340 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW-TLEKEGKKP 471
+ QL + SK+IV+ TGAG+S S GIPDFR GV+ T+EK+ P
Sbjct: 293 VCQLFESSKNIVIITGAGVSVSCGIPDFRSKGGVYETIEKKYNLP 337
>UniRef50_A7EMW8 Cluster: Putative uncharacterized protein; n=1;
Sclerotinia sclerotiorum 1980|Rep: Putative
uncharacterized protein - Sclerotinia sclerotiorum 1980
Length = 533
Score = 49.6 bits (113), Expect = 6e-05
Identities = 24/39 (61%), Positives = 30/39 (76%), Gaps = 1/39 (2%)
Frame = +1
Query: 349 LVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWT-LEKEG 462
L+K++K I+V TGAGISTS GIPDFR NG++ LE G
Sbjct: 203 LIKNAKKIIVITGAGISTSLGIPDFRSANGLYAQLEDTG 241
>UniRef50_Q8CJM9 Cluster: NAD-dependent deacetylase 2; n=3;
Actinomycetales|Rep: NAD-dependent deacetylase 2 -
Streptomyces coelicolor
Length = 241
Score = 49.6 bits (113), Expect = 6e-05
Identities = 33/103 (32%), Positives = 49/103 (47%), Gaps = 20/103 (19%)
Frame = +1
Query: 370 IVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKK----------PTI---------NVSFA 492
+ + +GAG+ST +GIPD+RGPNG+W + E +K P I + +
Sbjct: 7 VAILSGAGVSTDSGIPDYRGPNGLWRRDPEAEKLVTYEYYMGDPEIRRRSWLMRRDSAAL 66
Query: 493 DAQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSGV-PRKFL 618
A+P H ++QN+DGLH +GV RK L
Sbjct: 67 HAEPNAAHRAVADLERRGVPVRVLTQNVDGLHQLAGVSARKVL 109
>UniRef50_Q5YR82 Cluster: Putative Sir2 family regulator; n=1;
Nocardia farcinica|Rep: Putative Sir2 family regulator -
Nocardia farcinica
Length = 248
Score = 49.2 bits (112), Expect = 8e-05
Identities = 22/29 (75%), Positives = 23/29 (79%)
Frame = +1
Query: 361 SKHIVVHTGAGISTSAGIPDFRGPNGVWT 447
S I V TGAGIST +GIPDFRGP GVWT
Sbjct: 9 SGRIGVLTGAGISTDSGIPDFRGPRGVWT 37
>UniRef50_UPI00015B57C0 Cluster: PREDICTED: similar to GA18743-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
GA18743-PA - Nasonia vitripennis
Length = 871
Score = 48.8 bits (111), Expect = 1e-04
Identities = 19/36 (52%), Positives = 30/36 (83%)
Frame = +1
Query: 340 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWT 447
+ +L+K+SK+I+V TGAG+S S GIPDFR +G+++
Sbjct: 197 VVELIKNSKNIIVLTGAGVSVSCGIPDFRSRDGIYS 232
>UniRef50_Q2YZT2 Cluster: Putative uncharacterized protein; n=1;
uncultured delta proteobacterium|Rep: Putative
uncharacterized protein - uncultured delta
proteobacterium
Length = 254
Score = 48.8 bits (111), Expect = 1e-04
Identities = 30/102 (29%), Positives = 49/102 (48%), Gaps = 17/102 (16%)
Frame = +1
Query: 346 QLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWT---------LEKEGKKPT-------- 474
Q++K SK+++ TGAGIS +GIPDFR P G+W+ ++ + P
Sbjct: 11 QMIK-SKYVIAMTGAGISVESGIPDFRSPGGLWSRFDPFEYAHIDAFKRDPAKVWKMLLE 69
Query: 475 INVSFADAQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSG 600
I+ A+P + H ++QNID +H ++G
Sbjct: 70 IDEVLNQAKPNRAHYALAKLEAAGILKAIITQNIDNMHQRAG 111
>UniRef50_A7HL19 Cluster: Silent information regulator protein Sir2;
n=1; Fervidobacterium nodosum Rt17-B1|Rep: Silent
information regulator protein Sir2 - Fervidobacterium
nodosum Rt17-B1
Length = 244
Score = 48.8 bits (111), Expect = 1e-04
Identities = 33/108 (30%), Positives = 50/108 (46%), Gaps = 16/108 (14%)
Frame = +1
Query: 325 QKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWT--------LEKEGKKPTIN 480
++ + L +K+SK V TGAG+S +GIPDFR NGV++ ++ + P
Sbjct: 2 EEILTLVSWLKNSKFTTVLTGAGVSVPSGIPDFRSKNGVYSKWGQEIFDIDLFHQNPDRF 61
Query: 481 VSFA--------DAQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSG 600
FA D +P + H ++QNID LH K+G
Sbjct: 62 YEFAKQELIKMLDVEPNEIHYLLAYLEKLNIVKGVITQNIDNLHKKAG 109
>UniRef50_A4J646 Cluster: Silent information regulator protein Sir2;
n=2; Peptococcaceae|Rep: Silent information regulator
protein Sir2 - Desulfotomaculum reducens MI-1
Length = 256
Score = 48.8 bits (111), Expect = 1e-04
Identities = 35/108 (32%), Positives = 50/108 (46%), Gaps = 18/108 (16%)
Frame = +1
Query: 340 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPN-GVW---------TLEKEGKKP----TI 477
L +L+K + + TGAGIST +GIPDFR N G+W +++ K P +
Sbjct: 10 LTELIKKAGKTIALTGAGISTESGIPDFRSKNTGLWNQYDPQEVASIQALKKNPESFYAL 69
Query: 478 NVSFAD----AQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSGVPR 609
N + D A+P H ++QNIDGLH +G R
Sbjct: 70 NFQWWDVCLKAKPNNAHFALARLEKMGWLLGVITQNIDGLHQHAGSKR 117
>UniRef50_A1HLU5 Cluster: Silent information regulator protein Sir2;
n=1; Thermosinus carboxydivorans Nor1|Rep: Silent
information regulator protein Sir2 - Thermosinus
carboxydivorans Nor1
Length = 261
Score = 48.8 bits (111), Expect = 1e-04
Identities = 33/103 (32%), Positives = 47/103 (45%), Gaps = 16/103 (15%)
Frame = +1
Query: 340 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW--------TLEKEGKKPTINVSFA- 492
+A + + +IVV TGAG+ST +G+PDFR G+W TL KP F
Sbjct: 9 IAAAWRSANNIVVFTGAGMSTESGLPDFRSKQGLWKDRPETLATLAALKAKPDEFYFFYQ 68
Query: 493 -------DAQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSG 600
+ QP H+ V+QN+DGLH ++G
Sbjct: 69 WRIARLWEVQPNPGHLALAELAQAGFVTKLVTQNVDGLHQRAG 111
>UniRef50_Q8ZU41 Cluster: NAD-dependent deacetylase 1; n=3;
Pyrobaculum|Rep: NAD-dependent deacetylase 1 -
Pyrobaculum aerophilum
Length = 254
Score = 48.8 bits (111), Expect = 1e-04
Identities = 21/35 (60%), Positives = 26/35 (74%)
Frame = +1
Query: 340 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 444
+A L+ S V TGAG+ST++GIPDFRGP GVW
Sbjct: 13 VASLIARSSCNVALTGAGVSTASGIPDFRGPQGVW 47
>UniRef50_Q3E2I1 Cluster: Silent information regulator protein Sir2;
n=7; Bacteria|Rep: Silent information regulator protein
Sir2 - Chloroflexus aurantiacus J-10-fl
Length = 254
Score = 48.4 bits (110), Expect = 1e-04
Identities = 36/118 (30%), Positives = 53/118 (44%), Gaps = 18/118 (15%)
Frame = +1
Query: 310 NDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFR-GPNGVWT-LEKE-------- 459
ND L+ +LA + ++H+ V TGAG+S +GIP FR G+W+ + E
Sbjct: 2 ND-LDDVITILATALSTARHVTVLTGAGVSAESGIPTFRDAQTGLWSHFDPEELASPAGF 60
Query: 460 GKKPTI--------NVSFADAQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSGVPR 609
+ P + V AQP H V+QNIDGLH ++G P+
Sbjct: 61 ARNPALVWRWYAERRVKACTAQPNPAHHALADLATLVPRLTLVTQNIDGLHQRAGSPQ 118
>UniRef50_A4VDQ9 Cluster: Chromatin regulatory protein sir2; n=1;
Tetrahymena thermophila SB210|Rep: Chromatin regulatory
protein sir2 - Tetrahymena thermophila SB210
Length = 279
Score = 48.0 bits (109), Expect = 2e-04
Identities = 35/108 (32%), Positives = 54/108 (50%), Gaps = 23/108 (21%)
Frame = +1
Query: 364 KHIVVHTGAGISTSAGIPDFRG-----------------PNGVWTLE--KEGKKPTINV- 483
K I+V TGAGIST+AGIPDFR P ++T++ ++ KP +
Sbjct: 31 KKIIVLTGAGISTNAGIPDFRSKDTGLYARLKKSGQFSYPEQIFTIDYYQQNHKPFYEIC 90
Query: 484 -SFA--DAQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSGVPRKFL 618
F + +P ++H ++QNIDGL LK+G+ +K+L
Sbjct: 91 REFVQKEYEPQQSHKFITELAKQNLLYLNITQNIDGLELKAGLDKKYL 138
>UniRef50_Q9WYW0 Cluster: NAD-dependent deacetylase; n=4;
Thermotoga|Rep: NAD-dependent deacetylase - Thermotoga
maritima
Length = 246
Score = 48.0 bits (109), Expect = 2e-04
Identities = 33/100 (33%), Positives = 46/100 (46%), Gaps = 16/100 (16%)
Frame = +1
Query: 349 LVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEG--------KKPTINVSFA---- 492
L+ +S+ V TGAGIST +GIPDFRGPNG++ + P FA
Sbjct: 9 LLNESRLTVTLTGAGISTPSGIPDFRGPNGIYKKYSQNVFDIDFFYSHPEEFYRFAKEGI 68
Query: 493 ----DAQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSG 600
A+P H+ ++QNID LH ++G
Sbjct: 69 FPMLQAKPNLAHVLLAKLEEKGLIEAVITQNIDRLHQRAG 108
>UniRef50_A6RRE3 Cluster: Putative uncharacterized protein; n=1;
Botryotinia fuckeliana B05.10|Rep: Putative
uncharacterized protein - Botryotinia fuckeliana B05.10
Length = 526
Score = 47.6 bits (108), Expect = 2e-04
Identities = 20/33 (60%), Positives = 27/33 (81%)
Frame = +1
Query: 346 QLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 444
+L++ +K I+V TGAGISTS GIPDFR NG++
Sbjct: 198 ELIRGAKKIIVITGAGISTSLGIPDFRSANGLY 230
>UniRef50_Q5KZE8 Cluster: NAD-dependent deacetylase 2; n=3;
Bacteria|Rep: NAD-dependent deacetylase 2 - Geobacillus
kaustophilus
Length = 247
Score = 47.6 bits (108), Expect = 2e-04
Identities = 21/38 (55%), Positives = 28/38 (73%)
Frame = +1
Query: 340 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLE 453
LAQ +K++ I V TGAG+ST +GIPDFR NG++ E
Sbjct: 7 LAQWIKEANTIAVLTGAGMSTESGIPDFRSENGLYAQE 44
>UniRef50_Q5KA61 Cluster: Histone deacetylase, putative; n=1;
Filobasidiella neoformans|Rep: Histone deacetylase,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 596
Score = 47.2 bits (107), Expect = 3e-04
Identities = 23/40 (57%), Positives = 30/40 (75%), Gaps = 1/40 (2%)
Frame = +1
Query: 349 LVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWT-LEKEGK 465
L+ SK I+V +GAGISTS GIPDFR G++ L++EGK
Sbjct: 152 LLAKSKKIIVLSGAGISTSCGIPDFRSSTGLYAQLQEEGK 191
>UniRef50_A6R1B0 Cluster: Predicted protein; n=2; Onygenales|Rep:
Predicted protein - Ajellomyces capsulatus NAm1
Length = 547
Score = 47.2 bits (107), Expect = 3e-04
Identities = 26/55 (47%), Positives = 35/55 (63%), Gaps = 1/55 (1%)
Frame = +1
Query: 337 LLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW-TLEKEGKKPTINVSFADA 498
LL + ++ + IVV GAGIS SAGIPDFR +G++ TL+K+ K T DA
Sbjct: 94 LLLKALQKKRKIVVIAGAGISVSAGIPDFRSAHGLFKTLKKDHKLKTSGKQLFDA 148
>UniRef50_A2Q9C4 Cluster: Contig An01c0250, complete genome; n=18;
Pezizomycotina|Rep: Contig An01c0250, complete genome -
Aspergillus niger
Length = 495
Score = 47.2 bits (107), Expect = 3e-04
Identities = 25/50 (50%), Positives = 33/50 (66%), Gaps = 2/50 (4%)
Frame = +1
Query: 283 LGVPEKFDSNDKLNQKCVL--LAQLVKDSKHIVVHTGAGISTSAGIPDFR 426
+ + +F KL Q + +L+K+SK+IVV TGAGISTS GIPDFR
Sbjct: 150 IAISREFSRRPKLPQYNTIDDAVKLLKESKNIVVLTGAGISTSLGIPDFR 199
>UniRef50_Q8CNF4 Cluster: NAD-dependent deacetylase; n=17;
Staphylococcus|Rep: NAD-dependent deacetylase -
Staphylococcus epidermidis (strain ATCC 12228)
Length = 246
Score = 47.2 bits (107), Expect = 3e-04
Identities = 33/108 (30%), Positives = 48/108 (44%), Gaps = 21/108 (19%)
Frame = +1
Query: 340 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW-TLEKEGKKPTINVS---------- 486
L +V +S IV TGAG+S ++GIPDFR G++ + K+G+ P +S
Sbjct: 9 LKDIVNNSNQIVFFTGAGVSVASGIPDFRSMGGLYDEISKDGQSPEYLLSIDHLHDNKES 68
Query: 487 ----------FADAQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSG 600
AD +P H ++QNIDGLH +G
Sbjct: 69 FINFYHERLLIADKKPNIVHQWIAQLENQQKSLGVITQNIDGLHEDAG 116
>UniRef50_A7B9E8 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 251
Score = 46.8 bits (106), Expect = 4e-04
Identities = 33/111 (29%), Positives = 48/111 (43%), Gaps = 17/111 (15%)
Frame = +1
Query: 319 LNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKPTI-NVSFAD 495
+N LA + S V GAG+ST +GIPDFRG NG + E+E T+ ++ F +
Sbjct: 1 MNSDVSTLAAWIAASPSTVFFGGAGVSTESGIPDFRGANGFYFQEREIPLETVLSIDFFE 60
Query: 496 ----------------AQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSG 600
+P H ++QNIDGLH ++G
Sbjct: 61 RHPQAYWEWFHEIYRPVEPNGAHRALASLEAAGRLDAVITQNIDGLHQRAG 111
>UniRef50_A1ZPG8 Cluster: NAD-dependent deacetylase; n=1;
Microscilla marina ATCC 23134|Rep: NAD-dependent
deacetylase - Microscilla marina ATCC 23134
Length = 278
Score = 46.8 bits (106), Expect = 4e-04
Identities = 35/111 (31%), Positives = 48/111 (43%), Gaps = 22/111 (19%)
Frame = +1
Query: 334 VLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKP----TI-------- 477
+L AQ + K I TGAGIS +G+P +RG +G+W KP T+
Sbjct: 10 LLCAQALAQDKLITFLTGAGISAESGVPTYRGTDGIWVEGSRNYKPEEFATLRFFKENPA 69
Query: 478 ---------NVSFADAQPTKTHM-XXXXXXXXXXXXXXVSQNIDGLHLKSG 600
VSF D QP H+ ++QNID LH+K+G
Sbjct: 70 EVWKFVLYRKVSFRDLQPNAGHLALASTEVLLPNNFRLITQNIDRLHIKAG 120
>UniRef50_O96505 Cluster: SIR2; n=4; Sophophora|Rep: SIR2 -
Drosophila melanogaster (Fruit fly)
Length = 823
Score = 46.8 bits (106), Expect = 4e-04
Identities = 20/32 (62%), Positives = 25/32 (78%)
Frame = +1
Query: 349 LVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 444
LVK S+ I+V TGAG+S S GIPDFR NG++
Sbjct: 215 LVKKSQKIIVLTGAGVSVSCGIPDFRSTNGIY 246
>UniRef50_Q5AQ47 Cluster: Potential Sir2 family histone deacetylase;
n=2; Candida albicans|Rep: Potential Sir2 family histone
deacetylase - Candida albicans (Yeast)
Length = 657
Score = 46.8 bits (106), Expect = 4e-04
Identities = 20/35 (57%), Positives = 29/35 (82%)
Frame = +1
Query: 346 QLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTL 450
+L+++SK+I+V TGAGISTS GIPDFR G +++
Sbjct: 296 KLIENSKNIMVITGAGISTSLGIPDFRSSQGFYSM 330
>UniRef50_Q12Y78 Cluster: Silent information regulator protein Sir2;
n=1; Methanococcoides burtonii DSM 6242|Rep: Silent
information regulator protein Sir2 - Methanococcoides
burtonii (strain DSM 6242)
Length = 245
Score = 46.8 bits (106), Expect = 4e-04
Identities = 35/104 (33%), Positives = 52/104 (50%), Gaps = 17/104 (16%)
Frame = +1
Query: 340 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW---------TLEKEGKKPTI----N 480
L L+++S++ VV TGAG+ST +GIPDFRG +GV+ +++ K P +
Sbjct: 4 LFSLLENSEYCVVLTGAGVSTFSGIPDFRGRSGVYNKFDADLIFSIDHFNKDPAYFYAHS 63
Query: 481 VSF----ADAQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSG 600
SF QP+ H ++QNID LH K+G
Sbjct: 64 KSFIYDLEHRQPSIVHSVLSKLEEKGIIKAIITQNIDMLHQKAG 107
>UniRef50_A7DQD6 Cluster: Silent information regulator protein Sir2;
n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep:
Silent information regulator protein Sir2 - Candidatus
Nitrosopumilus maritimus SCM1
Length = 242
Score = 46.8 bits (106), Expect = 4e-04
Identities = 35/100 (35%), Positives = 46/100 (46%), Gaps = 17/100 (17%)
Frame = +1
Query: 352 VKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKPTINVSFAD------------ 495
VK++K IV TGAGIS +GIP FRG +G+W K TI+ + D
Sbjct: 11 VKNAKKIVFVTGAGISQESGIPTFRGKDGLWRNYDAMKLATIDAFYDDPKLVWEWYNERR 70
Query: 496 -----AQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSG 600
A P + H ++QNIDGLH K+G
Sbjct: 71 HNIFSANPNQGH-KAIAELEKFADVVSLTQNIDGLHQKAG 109
>UniRef50_Q8REC3 Cluster: NAD-dependent deacetylase; n=3;
Fusobacterium nucleatum|Rep: NAD-dependent deacetylase -
Fusobacterium nucleatum subsp. nucleatum
Length = 252
Score = 46.8 bits (106), Expect = 4e-04
Identities = 34/118 (28%), Positives = 58/118 (49%), Gaps = 21/118 (17%)
Frame = +1
Query: 310 NDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW-TLEKEGKKPT---- 474
+ K ++K + L +++K++K++V GAG ST +G+ DFRG +G++ TL K+ +P
Sbjct: 2 DSKRDEKILELVKILKNTKYLVFFGGAGTSTDSGVKDFRGKDGLYKTLYKDKYRPEEVLS 61
Query: 475 ---------INVSFADAQ-------PTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSG 600
I + + + + P K HM ++QNID LH SG
Sbjct: 62 SDFFYSHRDIFMKYVEKELNIKGLKPNKGHMALVELEKIGILKAVITQNIDDLHQVSG 119
>UniRef50_A1HU63 Cluster: Silent information regulator protein Sir2;
n=1; Thermosinus carboxydivorans Nor1|Rep: Silent
information regulator protein Sir2 - Thermosinus
carboxydivorans Nor1
Length = 243
Score = 46.4 bits (105), Expect = 5e-04
Identities = 33/102 (32%), Positives = 48/102 (47%), Gaps = 15/102 (14%)
Frame = +1
Query: 340 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGV----------WTLEKEGK-----KPT 474
L + ++ + H V TGAGIST++GIPDFRG N + + + K +P
Sbjct: 10 LVECLRAANHATVLTGAGISTASGIPDFRGINRINADLSQLTSTFMRRQPAKAYELLRPF 69
Query: 475 INVSFADAQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSG 600
I A A P H+ ++QNIDGLH ++G
Sbjct: 70 IQTILA-ASPNAAHIGLARLLAKGVLRGLMTQNIDGLHSRAG 110
>UniRef50_Q23A43 Cluster: Transcriptional regulator, Sir2 family
protein; n=2; Tetrahymena thermophila SB210|Rep:
Transcriptional regulator, Sir2 family protein -
Tetrahymena thermophila SB210
Length = 503
Score = 46.4 bits (105), Expect = 5e-04
Identities = 22/40 (55%), Positives = 26/40 (65%)
Frame = +1
Query: 343 AQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEG 462
AQL KD K +V TGAGIS ++GIP FRG EK+G
Sbjct: 118 AQLFKDKKKVVFLTGAGISVASGIPTFRGVGAAPLFEKDG 157
>UniRef50_Q1RPU3 Cluster: Zinc finger protein; n=1; Ciona
intestinalis|Rep: Zinc finger protein - Ciona
intestinalis (Transparent sea squirt)
Length = 737
Score = 46.4 bits (105), Expect = 5e-04
Identities = 23/56 (41%), Positives = 36/56 (64%)
Frame = +1
Query: 280 ILGVPEKFDSNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWT 447
I+ P++ D +N + +L+K SK I+V TGAG+S S GIPDFR +G+++
Sbjct: 162 IISEPKRRKKLDTVNTLSDAI-RLIKTSKKILVLTGAGVSVSCGIPDFRSRDGIYS 216
>UniRef50_Q21921 Cluster: NAD-dependent deacetylase SIR2 homolog;
n=2; Caenorhabditis|Rep: NAD-dependent deacetylase SIR2
homolog - Caenorhabditis elegans
Length = 607
Score = 46.4 bits (105), Expect = 5e-04
Identities = 19/33 (57%), Positives = 25/33 (75%)
Frame = +1
Query: 346 QLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 444
+L K KHI+V TGAG+S S GIPDFR +G++
Sbjct: 140 ELFKTKKHILVLTGAGVSVSCGIPDFRSKDGIY 172
>UniRef50_O07595 Cluster: NAD-dependent deacetylase; n=3;
Bacillus|Rep: NAD-dependent deacetylase - Bacillus
subtilis
Length = 247
Score = 46.4 bits (105), Expect = 5e-04
Identities = 18/33 (54%), Positives = 26/33 (78%)
Frame = +1
Query: 349 LVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWT 447
++ +++ IVV TGAG+ST +GIPDFR G+WT
Sbjct: 7 ILHEAQRIVVLTGAGMSTESGIPDFRSAGGIWT 39
>UniRef50_A6TNA0 Cluster: Silent information regulator protein Sir2;
n=1; Alkaliphilus metalliredigens QYMF|Rep: Silent
information regulator protein Sir2 - Alkaliphilus
metalliredigens QYMF
Length = 249
Score = 46.0 bits (104), Expect = 7e-04
Identities = 19/46 (41%), Positives = 28/46 (60%)
Frame = +1
Query: 307 SNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 444
+ +++ + LA L+K SK V+ TGAG+ T + IPDFR G W
Sbjct: 6 NGERMKDGVIKLASLIKKSKDTVILTGAGMDTESNIPDFRSEKGWW 51
>UniRef50_A6G0H3 Cluster: Silent information regulator protein Sir2;
n=1; Plesiocystis pacifica SIR-1|Rep: Silent information
regulator protein Sir2 - Plesiocystis pacifica SIR-1
Length = 288
Score = 46.0 bits (104), Expect = 7e-04
Identities = 19/34 (55%), Positives = 24/34 (70%)
Frame = +1
Query: 370 IVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKP 471
+VV TGAGIS +GIP FRGP G WT+ + +P
Sbjct: 31 VVVTTGAGISAESGIPTFRGPEGYWTVGAKEYRP 64
>UniRef50_A6DES9 Cluster: Transcriptional regulator, Sir2 family
protein; n=2; Epsilonproteobacteria|Rep: Transcriptional
regulator, Sir2 family protein - Caminibacter
mediatlanticus TB-2
Length = 264
Score = 46.0 bits (104), Expect = 7e-04
Identities = 22/57 (38%), Positives = 33/57 (57%)
Frame = +1
Query: 337 LLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKPTINVSFADAQPT 507
L A +K++K++++ GAG+ +G+PDFRG G W KK +N A A PT
Sbjct: 6 LAANEIKNAKYLLITAGAGMGVDSGLPDFRGNEGFWRAYPIAKKLGLNFQ-ALANPT 61
>UniRef50_Q2GZ88 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized
protein - Chaetomium globosum (Soil fungus)
Length = 895
Score = 46.0 bits (104), Expect = 7e-04
Identities = 20/37 (54%), Positives = 29/37 (78%)
Frame = +1
Query: 340 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTL 450
+A + S+ +VV TGAGIST++GIPDFR NG+++L
Sbjct: 17 IANTLWKSRKVVVITGAGISTNSGIPDFRSENGLYSL 53
>UniRef50_Q73KE1 Cluster: NAD-dependent deacetylase; n=1; Treponema
denticola|Rep: NAD-dependent deacetylase - Treponema
denticola
Length = 251
Score = 46.0 bits (104), Expect = 7e-04
Identities = 34/105 (32%), Positives = 48/105 (45%), Gaps = 17/105 (16%)
Frame = +1
Query: 337 LLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKPTINVSFAD------- 495
L +++ K ++H+V TGAGIST AGI DFRG +G++ K I+V + D
Sbjct: 11 LFSEITK-ARHLVAFTGAGISTLAGIKDFRGKDGLYKQPNTEKMFDIDVFYRDPSVYYGM 69
Query: 496 ----------AQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSG 600
QP H ++QNID LH K+G
Sbjct: 70 AKEFIYGLEEKQPAIVHTVLADLEKRGILKAVITQNIDLLHQKAG 114
>UniRef50_Q97MB4 Cluster: NAD-dependent deacetylase; n=7;
Bacteria|Rep: NAD-dependent deacetylase - Clostridium
acetobutylicum
Length = 245
Score = 46.0 bits (104), Expect = 7e-04
Identities = 37/117 (31%), Positives = 51/117 (43%), Gaps = 21/117 (17%)
Frame = +1
Query: 313 DKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW-TLEKEGKKPTINVS- 486
DK+N+ L ++V +S IV GAG+ST + IPDFR NG++ T P + +S
Sbjct: 5 DKINE----LKKIVAESSSIVFFGGAGVSTESNIPDFRSENGLYKTKNNFSYPPEVMLSH 60
Query: 487 -------------------FADAQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSG 600
F DA+P H V+QNIDGLH +G
Sbjct: 61 TFFKNHTEDFFEFYREKMIFKDAKPNAAHYSLAKIEEQGKLKAIVTQNIDGLHQLAG 117
>UniRef50_Q5L014 Cluster: NAD-dependent deacetylase 1; n=7;
Bacillaceae|Rep: NAD-dependent deacetylase 1 -
Geobacillus kaustophilus
Length = 242
Score = 46.0 bits (104), Expect = 7e-04
Identities = 33/101 (32%), Positives = 45/101 (44%), Gaps = 18/101 (17%)
Frame = +1
Query: 361 SKHIVVHTGAGISTSAGIPDFRGP-NGVWTLEKEGKKPTINV------SFAD-------- 495
S+H VV TGAG+ST +G+PDFR P G+W + TI+ SF +
Sbjct: 10 SRHTVVLTGAGMSTESGLPDFRSPRTGLWARFNPSELATIDALYHRRESFVEFYQYRIRT 69
Query: 496 ---AQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSGVPR 609
QP H V+QN+DG H ++G R
Sbjct: 70 LQQCQPHDGHRLLADWERRGIVQTIVTQNVDGFHQEAGSRR 110
>UniRef50_Q8FUC8 Cluster: NAD-dependent deacetylase 1; n=6;
Corynebacterium|Rep: NAD-dependent deacetylase 1 -
Corynebacterium efficiens
Length = 281
Score = 46.0 bits (104), Expect = 7e-04
Identities = 30/94 (31%), Positives = 44/94 (46%), Gaps = 17/94 (18%)
Frame = +1
Query: 370 IVVHTGAGISTSAGIPDFRGPNG------VWTLEKEGKKPTINVSF-----------ADA 498
++ TGAG+ST +GIPD+R P G T ++ P + + ADA
Sbjct: 19 VLAVTGAGVSTDSGIPDYRSPRGSLNQGRPMTYQEFRFDPVASHRYWARSFVGWRVMADA 78
Query: 499 QPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSG 600
QP +TH V+QN+DGLH ++G
Sbjct: 79 QPNRTHYALVELERAGLLSGIVTQNVDGLHRRAG 112
>UniRef50_A6PTK3 Cluster: Silent information regulator protein Sir2;
n=1; Victivallis vadensis ATCC BAA-548|Rep: Silent
information regulator protein Sir2 - Victivallis
vadensis ATCC BAA-548
Length = 248
Score = 45.6 bits (103), Expect = 0.001
Identities = 21/42 (50%), Positives = 29/42 (69%)
Frame = +1
Query: 340 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGK 465
L Q++++S+ + TGAGIST +GI DFRG NGV+ GK
Sbjct: 5 LKQMLQESRRTLAFTGAGISTLSGIRDFRGKNGVYLEPWHGK 46
>UniRef50_A5UYK2 Cluster: Silent information regulator protein Sir2;
n=2; Roseiflexus|Rep: Silent information regulator
protein Sir2 - Roseiflexus sp. RS-1
Length = 261
Score = 45.6 bits (103), Expect = 0.001
Identities = 20/34 (58%), Positives = 24/34 (70%)
Frame = +1
Query: 343 AQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 444
A L+ + V TGAGIST +GIPDFRGP+G W
Sbjct: 15 ADLLGRAHSAVAITGAGISTPSGIPDFRGPDGAW 48
>UniRef50_Q5BVF7 Cluster: SJCHGC03105 protein; n=2; Schistosoma
japonicum|Rep: SJCHGC03105 protein - Schistosoma
japonicum (Blood fluke)
Length = 181
Score = 45.6 bits (103), Expect = 0.001
Identities = 26/54 (48%), Positives = 35/54 (64%), Gaps = 3/54 (5%)
Frame = +1
Query: 340 LAQLVKDSK--HIVVHTGAGISTSAGIPDFRGP-NGVWTLEKEGKKPTINVSFA 492
++QL++D K IV GAGIST+AGIPDFR P +GV+ +E PT F+
Sbjct: 52 VSQLIQDGKINKIVTMVGAGISTAAGIPDFRSPSSGVYDNLEEFNLPTPTTIFS 105
>UniRef50_A0LG97 Cluster: Silent information regulator protein Sir2;
n=1; Syntrophobacter fumaroxidans MPOB|Rep: Silent
information regulator protein Sir2 - Syntrophobacter
fumaroxidans (strain DSM 10017 / MPOB)
Length = 248
Score = 45.2 bits (102), Expect = 0.001
Identities = 19/35 (54%), Positives = 27/35 (77%)
Frame = +1
Query: 343 AQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWT 447
A+L+ S++ VV TGAGIS +GIPDFR +G+W+
Sbjct: 8 AELLLRSRYTVVLTGAGISVESGIPDFRSKDGLWS 42
>UniRef50_Q9FY91 Cluster: SIR2-family protein; n=12;
Magnoliophyta|Rep: SIR2-family protein - Arabidopsis
thaliana (Mouse-ear cress)
Length = 451
Score = 45.2 bits (102), Expect = 0.001
Identities = 21/50 (42%), Positives = 30/50 (60%)
Frame = +1
Query: 340 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKPTINVSF 489
L +L + S + + TGAG+ST GIPD+R PNG ++ G KP + F
Sbjct: 161 LYRLFEQSSRLTILTGAGVSTECGIPDYRSPNGAYS---SGFKPITHQEF 207
>UniRef50_A7SX90 Cluster: Predicted protein; n=3; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 306
Score = 45.2 bits (102), Expect = 0.001
Identities = 18/35 (51%), Positives = 27/35 (77%)
Frame = +1
Query: 340 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 444
+ +L+K K+I+V TGAG+S S GIPDFR +G++
Sbjct: 62 VVRLIKKCKNIIVLTGAGVSVSCGIPDFRSRDGIY 96
>UniRef50_A7EC18 Cluster: Putative uncharacterized protein; n=1;
Sclerotinia sclerotiorum 1980|Rep: Putative
uncharacterized protein - Sclerotinia sclerotiorum 1980
Length = 446
Score = 45.2 bits (102), Expect = 0.001
Identities = 22/33 (66%), Positives = 28/33 (84%), Gaps = 2/33 (6%)
Frame = +1
Query: 340 LAQLVKD--SKHIVVHTGAGISTSAGIPDFRGP 432
+A+ +K+ +K+IVV TGAGISTSAGIPDFR P
Sbjct: 27 VAEFIKNGQAKNIVVLTGAGISTSAGIPDFRSP 59
>UniRef50_UPI0000D55B5A Cluster: PREDICTED: similar to CG5216-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG5216-PA - Tribolium castaneum
Length = 722
Score = 44.8 bits (101), Expect = 0.002
Identities = 18/35 (51%), Positives = 28/35 (80%)
Frame = +1
Query: 340 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 444
+ +LVK +++I+V TGAG+S S GIPDFR +G++
Sbjct: 204 VVRLVKGAQNIIVLTGAGVSVSCGIPDFRSRDGIY 238
>UniRef50_UPI000051AA14 Cluster: PREDICTED: similar to NAD-dependent
deacetylase sirtuin-1 (hSIRT1) (hSIR2) (SIR2-like
protein 1); n=1; Apis mellifera|Rep: PREDICTED: similar
to NAD-dependent deacetylase sirtuin-1 (hSIRT1) (hSIR2)
(SIR2-like protein 1) - Apis mellifera
Length = 868
Score = 44.8 bits (101), Expect = 0.002
Identities = 17/36 (47%), Positives = 28/36 (77%)
Frame = +1
Query: 340 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWT 447
+ +L+++S I+V TGAG+S S GIPDFR +G+++
Sbjct: 196 VVRLIRNSNRIIVLTGAGVSVSCGIPDFRSRDGIYS 231
>UniRef50_Q23E36 Cluster: Transcriptional regulator, Sir2 family
protein; n=1; Tetrahymena thermophila SB210|Rep:
Transcriptional regulator, Sir2 family protein -
Tetrahymena thermophila SB210
Length = 1348
Score = 44.8 bits (101), Expect = 0.002
Identities = 19/31 (61%), Positives = 25/31 (80%)
Frame = +1
Query: 355 KDSKHIVVHTGAGISTSAGIPDFRGPNGVWT 447
K +I+ TGAGISTS+GIPDFR PNG+++
Sbjct: 18 KQINNILFLTGAGISTSSGIPDFRSPNGLYS 48
>UniRef50_A2F8E1 Cluster: Transcriptional regulator, Sir2 family
protein; n=1; Trichomonas vaginalis G3|Rep:
Transcriptional regulator, Sir2 family protein -
Trichomonas vaginalis G3
Length = 331
Score = 44.8 bits (101), Expect = 0.002
Identities = 23/49 (46%), Positives = 32/49 (65%), Gaps = 3/49 (6%)
Frame = +1
Query: 331 CVLLAQLVKDS--KHIVVHTGAGISTSAGIPDFRGPN-GVWTLEKEGKK 468
C +LAQ + K+++V TGAGIST+AGIPDFR P G++ K +
Sbjct: 7 CEILAQKIISGNYKNVIVLTGAGISTAAGIPDFRSPAIGIYATLKSASR 55
>UniRef50_Q7S386 Cluster: Putative uncharacterized protein
NCU04859.1; n=1; Neurospora crassa|Rep: Putative
uncharacterized protein NCU04859.1 - Neurospora crassa
Length = 1327
Score = 44.8 bits (101), Expect = 0.002
Identities = 19/37 (51%), Positives = 29/37 (78%)
Frame = +1
Query: 340 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTL 450
+A + ++ +VV TGAGIST++GIPDFR NG+++L
Sbjct: 17 IANSLYKARKVVVITGAGISTNSGIPDFRSENGLYSL 53
>UniRef50_Q6CB00 Cluster: Similarities with tr|Q9UR39
Schizosaccharomyces pombe HST4P; n=1; Yarrowia
lipolytica|Rep: Similarities with tr|Q9UR39
Schizosaccharomyces pombe HST4P - Yarrowia lipolytica
(Candida lipolytica)
Length = 721
Score = 44.8 bits (101), Expect = 0.002
Identities = 27/65 (41%), Positives = 39/65 (60%), Gaps = 2/65 (3%)
Frame = +1
Query: 310 NDKLNQKCV-LLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW-TLEKEGKKPTINV 483
N +N+K + LL + +S+ +VV TGAGIS AGIPDFR G++ +L+ E T
Sbjct: 157 NSDINRKDLELLHHVFHNSQRLVVITGAGISVHAGIPDFRSDKGLFVSLKDEYNLKTTGK 216
Query: 484 SFADA 498
+ DA
Sbjct: 217 ALFDA 221
>UniRef50_Q0CR31 Cluster: NAD-dependent histone deacetylase SIR2;
n=2; Pezizomycotina|Rep: NAD-dependent histone
deacetylase SIR2 - Aspergillus terreus (strain NIH 2624)
Length = 1068
Score = 44.8 bits (101), Expect = 0.002
Identities = 24/50 (48%), Positives = 33/50 (66%), Gaps = 2/50 (4%)
Frame = +1
Query: 283 LGVPEKFDSNDKLNQKCVL--LAQLVKDSKHIVVHTGAGISTSAGIPDFR 426
+ + +F KL Q + +L+++SK+IVV TGAGISTS GIPDFR
Sbjct: 148 IAISREFSRRPKLPQYNSIDDAVKLLQESKNIVVLTGAGISTSLGIPDFR 197
>UniRef50_A6RSV6 Cluster: Putative uncharacterized protein; n=2;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 1195
Score = 44.8 bits (101), Expect = 0.002
Identities = 18/37 (48%), Positives = 29/37 (78%)
Frame = +1
Query: 340 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTL 450
+A ++ S+ +VV TGAGIST+ GIPDFR +G++++
Sbjct: 17 IADILAKSRKVVVVTGAGISTNVGIPDFRSEHGLYSM 53
>UniRef50_Q0LIC7 Cluster: Silent information regulator protein Sir2;
n=2; Bacteria|Rep: Silent information regulator protein
Sir2 - Herpetosiphon aurantiacus ATCC 23779
Length = 244
Score = 44.4 bits (100), Expect = 0.002
Identities = 18/27 (66%), Positives = 23/27 (85%)
Frame = +1
Query: 364 KHIVVHTGAGISTSAGIPDFRGPNGVW 444
++IVV TGAGIS ++G+ FRGPNGVW
Sbjct: 11 RNIVVLTGAGISVASGVRPFRGPNGVW 37
>UniRef50_Q6CQA7 Cluster: Kluyveromyces lactis strain NRRL Y-1140
chromosome D of strain NRRL Y- 1140 of Kluyveromyces
lactis; n=1; Kluyveromyces lactis|Rep: Kluyveromyces
lactis strain NRRL Y-1140 chromosome D of strain NRRL Y-
1140 of Kluyveromyces lactis - Kluyveromyces lactis
(Yeast) (Candida sphaerica)
Length = 399
Score = 44.4 bits (100), Expect = 0.002
Identities = 21/39 (53%), Positives = 27/39 (69%)
Frame = +1
Query: 340 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEK 456
L ++ SK IVV GAG+S +AGIPDFR NG++T K
Sbjct: 105 LTYVLSYSKRIVVVQGAGVSVAAGIPDFRSANGLFTTLK 143
>UniRef50_Q0UNC9 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 479
Score = 44.4 bits (100), Expect = 0.002
Identities = 19/31 (61%), Positives = 26/31 (83%)
Frame = +1
Query: 343 AQLVKDSKHIVVHTGAGISTSAGIPDFRGPN 435
A+L+++ K+I++ TGAGISTS GIPDFR N
Sbjct: 167 AKLLRERKNIMIITGAGISTSLGIPDFRSKN 197
>UniRef50_A6RXY5 Cluster: Putative uncharacterized protein; n=2;
Pezizomycotina|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 446
Score = 44.4 bits (100), Expect = 0.002
Identities = 20/24 (83%), Positives = 22/24 (91%)
Frame = +1
Query: 361 SKHIVVHTGAGISTSAGIPDFRGP 432
+K+IVV TGAGISTSAGIPDFR P
Sbjct: 36 AKNIVVMTGAGISTSAGIPDFRSP 59
>UniRef50_A1DG07 Cluster: SIR2 family histone deacetylase, putative;
n=3; Trichocomaceae|Rep: SIR2 family histone
deacetylase, putative - Neosartorya fischeri (strain
ATCC 1020 / DSM 3700 / NRRL 181)(Aspergillus
fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181))
Length = 425
Score = 44.4 bits (100), Expect = 0.002
Identities = 20/27 (74%), Positives = 22/27 (81%)
Frame = +1
Query: 355 KDSKHIVVHTGAGISTSAGIPDFRGPN 435
KD + IVV GAGISTSAGIPDFR P+
Sbjct: 33 KDVRRIVVMVGAGISTSAGIPDFRSPD 59
>UniRef50_Q67KQ0 Cluster: NAD-dependent deacetylase; n=1;
Symbiobacterium thermophilum|Rep: NAD-dependent
deacetylase - Symbiobacterium thermophilum
Length = 251
Score = 44.4 bits (100), Expect = 0.002
Identities = 30/105 (28%), Positives = 48/105 (45%), Gaps = 17/105 (16%)
Frame = +1
Query: 343 AQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW---------TLEKEGKKPT-----IN 480
A+ ++ S++ V TGAG ST +G+PDFR G+W ++ ++P
Sbjct: 9 ARALQASRYAVALTGAGASTESGLPDFRSNTGLWKDVDPVSLISMTALRRRPVDFYRFYR 68
Query: 481 VSFA---DAQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSGVP 606
+ F+ AQP H ++QN+DGLH +G P
Sbjct: 69 MRFSHLWGAQPNPVHKVLAALQREGLLKRLITQNVDGLHQAAGSP 113
>UniRef50_Q88ZA0 Cluster: NAD-dependent deacetylase; n=4;
Lactobacillus|Rep: NAD-dependent deacetylase -
Lactobacillus plantarum
Length = 234
Score = 44.4 bits (100), Expect = 0.002
Identities = 17/32 (53%), Positives = 26/32 (81%)
Frame = +1
Query: 352 VKDSKHIVVHTGAGISTSAGIPDFRGPNGVWT 447
++ ++HIV TGAG+ST +GIPD+R NG++T
Sbjct: 11 LQQAQHIVFMTGAGVSTPSGIPDYRSKNGLYT 42
>UniRef50_UPI000023F1DF Cluster: hypothetical protein FG02466.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG02466.1 - Gibberella zeae PH-1
Length = 1569
Score = 44.0 bits (99), Expect = 0.003
Identities = 22/34 (64%), Positives = 28/34 (82%)
Frame = +1
Query: 349 LVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTL 450
L+K K IVV TGAGIST++GIPDFR NG+++L
Sbjct: 638 LLKARKVIVV-TGAGISTNSGIPDFRSENGLYSL 670
>UniRef50_A4JS80 Cluster: Silent information regulator protein Sir2;
n=1; Burkholderia vietnamiensis G4|Rep: Silent
information regulator protein Sir2 - Burkholderia
vietnamiensis (strain G4 / LMG 22486)
(Burkholderiacepacia (strain R1808))
Length = 274
Score = 44.0 bits (99), Expect = 0.003
Identities = 17/35 (48%), Positives = 24/35 (68%)
Frame = +1
Query: 343 AQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWT 447
A + D+ IV+ GAG+S +G+PDFRG G+WT
Sbjct: 11 ADWIADADGIVIAAGAGMSVDSGLPDFRGTGGLWT 45
>UniRef50_Q7S6G9 Cluster: Putative uncharacterized protein
NCU04737.1; n=3; Sordariomycetes|Rep: Putative
uncharacterized protein NCU04737.1 - Neurospora crassa
Length = 670
Score = 44.0 bits (99), Expect = 0.003
Identities = 20/27 (74%), Positives = 24/27 (88%)
Frame = +1
Query: 346 QLVKDSKHIVVHTGAGISTSAGIPDFR 426
+L+K SK+I+V TGAGISTS GIPDFR
Sbjct: 201 ELLKRSKNIIVLTGAGISTSLGIPDFR 227
>UniRef50_Q4WT50 Cluster: SIR2 family histone deacetylase (Hst4),
putative; n=7; Trichocomaceae|Rep: SIR2 family histone
deacetylase (Hst4), putative - Aspergillus fumigatus
(Sartorya fumigata)
Length = 614
Score = 44.0 bits (99), Expect = 0.003
Identities = 22/42 (52%), Positives = 32/42 (76%), Gaps = 1/42 (2%)
Frame = +1
Query: 337 LLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW-TLEKE 459
LL + ++ + IVV GAGISTSAGIPDFR +G++ +L+K+
Sbjct: 125 LLVKTLRRHRKIVVIAGAGISTSAGIPDFRSTDGLFKSLQKK 166
>UniRef50_Q046W9 Cluster: NAD-dependent protein deacetylase, SIR2
family; n=6; Lactobacillus|Rep: NAD-dependent protein
deacetylase, SIR2 family - Lactobacillus gasseri (strain
ATCC 33323 / DSM 20243)
Length = 237
Score = 43.2 bits (97), Expect = 0.005
Identities = 20/66 (30%), Positives = 34/66 (51%)
Frame = +1
Query: 319 LNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKPTINVSFADA 498
LN + L + ++ H+ TGAG+ST + IPD+R NG++ E + ++
Sbjct: 3 LNNQIAALQADLNNAHHVTYLTGAGVSTPSHIPDYRSKNGIYNGISESPEQILSEDTLFH 62
Query: 499 QPTKTH 516
+P K H
Sbjct: 63 EPAKFH 68
>UniRef50_Q7SCL4 Cluster: Putative uncharacterized protein NCU00523.1;
n=2; Pezizomycotina|Rep: Putative uncharacterized protein
NCU00523.1 - Neurospora crassa
Length = 1220
Score = 43.2 bits (97), Expect = 0.005
Identities = 23/53 (43%), Positives = 30/53 (56%), Gaps = 2/53 (3%)
Frame = +1
Query: 280 ILGVPEKFDSNDKLNQKCVLLAQLVKDSK--HIVVHTGAGISTSAGIPDFRGP 432
+ VPE + + +A +K K +VV TGAGIST+AGIPDFR P
Sbjct: 848 VSAVPETTKPENLSERSLPAVADYIKSGKARKVVVLTGAGISTAAGIPDFRSP 900
>UniRef50_A7TQE2 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 602
Score = 43.2 bits (97), Expect = 0.005
Identities = 19/32 (59%), Positives = 24/32 (75%)
Frame = +1
Query: 352 VKDSKHIVVHTGAGISTSAGIPDFRGPNGVWT 447
+K +K I+V TGAGISTS GIPDFR G ++
Sbjct: 263 LKSAKKIIVLTGAGISTSLGIPDFRSSEGFYS 294
>UniRef50_Q5V4Q5 Cluster: NAD-dependent deacetylase; n=2;
Halobacteriaceae|Rep: NAD-dependent deacetylase -
Haloarcula marismortui (Halobacterium marismortui)
Length = 260
Score = 43.2 bits (97), Expect = 0.005
Identities = 16/35 (45%), Positives = 27/35 (77%)
Frame = +1
Query: 340 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 444
+A+ ++ ++ V TGAG+ST++GIP FRG +G+W
Sbjct: 19 VAEALRTAETAVALTGAGVSTASGIPSFRGDDGIW 53
>UniRef50_Q011Q8 Cluster: NAD-dependent deacetylase SIRT2; n=2;
Ostreococcus|Rep: NAD-dependent deacetylase SIRT2 -
Ostreococcus tauri
Length = 394
Score = 42.7 bits (96), Expect = 0.007
Identities = 18/28 (64%), Positives = 24/28 (85%)
Frame = +1
Query: 361 SKHIVVHTGAGISTSAGIPDFRGPNGVW 444
+K++VV TGAGIS SAGIPDFR +G++
Sbjct: 103 AKNVVVMTGAGISVSAGIPDFRSESGLY 130
>UniRef50_Q6BPH5 Cluster: Debaryomyces hansenii chromosome E of
strain CBS767 of Debaryomyces hansenii; n=2;
Saccharomycetaceae|Rep: Debaryomyces hansenii chromosome
E of strain CBS767 of Debaryomyces hansenii -
Debaryomyces hansenii (Yeast) (Torulaspora hansenii)
Length = 573
Score = 42.7 bits (96), Expect = 0.007
Identities = 19/32 (59%), Positives = 24/32 (75%)
Frame = +1
Query: 352 VKDSKHIVVHTGAGISTSAGIPDFRGPNGVWT 447
+K +K I+V TGAGISTS GIPDFR G ++
Sbjct: 257 IKKAKKILVVTGAGISTSLGIPDFRSSKGFYS 288
>UniRef50_Q0UMU7 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 670
Score = 42.7 bits (96), Expect = 0.007
Identities = 24/54 (44%), Positives = 32/54 (59%), Gaps = 1/54 (1%)
Frame = +1
Query: 340 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW-TLEKEGKKPTINVSFADA 498
L ++ + IVV GAGIS SAGIPDFR G++ +L+KE K + DA
Sbjct: 117 LLNVLHKKRKIVVIAGAGISVSAGIPDFRSATGLFNSLKKEHKLKSSGKDLFDA 170
>UniRef50_O94066 Cluster: Transcription regulatory protein; n=6;
Saccharomycetales|Rep: Transcription regulatory protein
- Candida albicans (Yeast)
Length = 331
Score = 42.7 bits (96), Expect = 0.007
Identities = 18/32 (56%), Positives = 23/32 (71%)
Frame = +1
Query: 340 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPN 435
+A+ VK+ K + GAGIST AGIPDFR P+
Sbjct: 11 VAEAVKNGKKVTFFNGAGISTGAGIPDFRSPD 42
>UniRef50_A2QFF9 Cluster: Complex: Sir2p is one of four Silent
Information Regulator genes in yeast. Sir2p; n=6;
Pezizomycotina|Rep: Complex: Sir2p is one of four Silent
Information Regulator genes in yeast. Sir2p -
Aspergillus niger
Length = 378
Score = 42.7 bits (96), Expect = 0.007
Identities = 20/32 (62%), Positives = 25/32 (78%), Gaps = 1/32 (3%)
Frame = +1
Query: 355 KDSKHIVVHTGAGISTSAGIPDFRGPN-GVWT 447
K K +VV GAGISTSAGIPDFR P+ G+++
Sbjct: 33 KPVKRVVVMVGAGISTSAGIPDFRSPDTGIYS 64
>UniRef50_Q96EB6 Cluster: NAD-dependent deacetylase sirtuin-1; n=29;
Euteleostomi|Rep: NAD-dependent deacetylase sirtuin-1 -
Homo sapiens (Human)
Length = 747
Score = 42.7 bits (96), Expect = 0.007
Identities = 17/33 (51%), Positives = 26/33 (78%)
Frame = +1
Query: 346 QLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 444
+L+++ K I+V TGAG+S S GIPDFR +G++
Sbjct: 248 KLLQECKKIIVLTGAGVSVSCGIPDFRSRDGIY 280
>UniRef50_Q9UR39 Cluster: NAD-dependent deacetylase hst4; n=1;
Schizosaccharomyces pombe|Rep: NAD-dependent deacetylase
hst4 - Schizosaccharomyces pombe (Fission yeast)
Length = 415
Score = 42.7 bits (96), Expect = 0.007
Identities = 19/36 (52%), Positives = 25/36 (69%)
Frame = +1
Query: 340 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWT 447
L ++ +K IVV TGAGIS AGIPDFR G+++
Sbjct: 50 LVSAIRKAKRIVVVTGAGISCDAGIPDFRSSEGLFS 85
>UniRef50_A7RMK8 Cluster: Predicted protein; n=5; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 273
Score = 42.3 bits (95), Expect = 0.009
Identities = 18/35 (51%), Positives = 24/35 (68%)
Frame = +1
Query: 340 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 444
L L+ +K+I+ TGAGIS +GIP FRG G+W
Sbjct: 18 LKDLLSKAKNILFLTGAGISAESGIPTFRGAGGLW 52
>UniRef50_A0D0F1 Cluster: Chromosome undetermined scaffold_33, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_33,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 264
Score = 42.3 bits (95), Expect = 0.009
Identities = 20/60 (33%), Positives = 31/60 (51%), Gaps = 5/60 (8%)
Frame = +1
Query: 340 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTL-----EKEGKKPTINVSFADAQP 504
+ + +K+ + ++ GAG+ +G+PDFRG G WT+ K G N SF D P
Sbjct: 1 MQKYIKECQAFIITAGAGMGVDSGLPDFRGNKGFWTVYRPFENKFGFTDCANPSFMDYNP 60
>UniRef50_Q6C8V5 Cluster: Similar to tr|Q9FY91 Arabidopsis thaliana
SIR2-family protein; n=1; Yarrowia lipolytica|Rep:
Similar to tr|Q9FY91 Arabidopsis thaliana SIR2-family
protein - Yarrowia lipolytica (Candida lipolytica)
Length = 411
Score = 42.3 bits (95), Expect = 0.009
Identities = 20/45 (44%), Positives = 31/45 (68%)
Frame = +1
Query: 355 KDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKPTINVSF 489
K++K ++ TGAGIST++G+PD+RGP G +T +PT+ F
Sbjct: 46 KNTKTAIL-TGAGISTASGLPDYRGPTGTYT-TNPNHQPTLYHEF 88
>UniRef50_Q6BPA4 Cluster: Debaryomyces hansenii chromosome E of
strain CBS767 of Debaryomyces hansenii; n=6;
Saccharomycetales|Rep: Debaryomyces hansenii chromosome
E of strain CBS767 of Debaryomyces hansenii -
Debaryomyces hansenii (Yeast) (Torulaspora hansenii)
Length = 438
Score = 42.3 bits (95), Expect = 0.009
Identities = 21/50 (42%), Positives = 35/50 (70%)
Frame = +1
Query: 307 SNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEK 456
SN+++ K +++++ S+ VV TGAGIS +AGIPDFR +G++ + K
Sbjct: 12 SNEQI--KLSEVSKIIFKSRKAVVLTGAGISCNAGIPDFRSSDGLYNMVK 59
>UniRef50_A5DSX8 Cluster: NAD-dependent histone deacetylase SIR2;
n=1; Lodderomyces elongisporus NRRL YB-4239|Rep:
NAD-dependent histone deacetylase SIR2 - Lodderomyces
elongisporus (Yeast) (Saccharomyces elongisporus)
Length = 568
Score = 42.3 bits (95), Expect = 0.009
Identities = 19/34 (55%), Positives = 25/34 (73%)
Frame = +1
Query: 349 LVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTL 450
L++ S I+V TGAGISTS GIPDFR G +++
Sbjct: 252 LIQKSHKILVITGAGISTSLGIPDFRSSQGFYSM 285
>UniRef50_A4RMS1 Cluster: Putative uncharacterized protein; n=2;
Sordariomycetes|Rep: Putative uncharacterized protein -
Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 666
Score = 42.3 bits (95), Expect = 0.009
Identities = 18/35 (51%), Positives = 26/35 (74%)
Frame = +1
Query: 340 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 444
L ++++ K IV+ GAGIS SAGIPDFR +G++
Sbjct: 132 LTKVLRKKKRIVIIAGAGISVSAGIPDFRSQSGLF 166
>UniRef50_UPI0000E49AD8 Cluster: PREDICTED: similar to NAD-dependent
deacetylase sirtuin 2 homolog; n=1; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to NAD-dependent
deacetylase sirtuin 2 homolog - Strongylocentrotus
purpuratus
Length = 400
Score = 41.9 bits (94), Expect = 0.012
Identities = 38/117 (32%), Positives = 55/117 (47%), Gaps = 24/117 (20%)
Frame = +1
Query: 340 LAQLVKDSK--HIVVHTGAGISTSAGIPDFRGP-NGVW-TLE----------------KE 459
+A +K+ K ++V +GAGISTSAGIPDFR P G++ L+ K+
Sbjct: 64 IADFIKEGKCKKVIVMSGAGISTSAGIPDFRTPGTGLYDNLQKYNLPNPQAIFEIGFFKQ 123
Query: 460 GKKPTINVS---FADA-QPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSGVPRKFL 618
+P +S F A PT +H +QNIDGL +GVP + +
Sbjct: 124 NPEPFFTLSKELFPGAFYPTPSHFFIHLLHEKGILLRHYTQNIDGLDRMAGVPDELI 180
>UniRef50_A3JEV2 Cluster: NAD-dependent deacetylase; n=2;
Marinobacter|Rep: NAD-dependent deacetylase -
Marinobacter sp. ELB17
Length = 300
Score = 41.9 bits (94), Expect = 0.012
Identities = 20/62 (32%), Positives = 35/62 (56%)
Frame = +1
Query: 325 QKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKPTINVSFADAQP 504
Q +LA + +++ TGAG+ST +GIPD+R +G W + K+P + +F +
Sbjct: 31 QAGAMLADYIHSHPRLLILTGAGVSTDSGIPDYRDGDGAW----KRKQPVQHQAFMGSVQ 86
Query: 505 TK 510
T+
Sbjct: 87 TR 88
>UniRef50_Q5KPC9 Cluster: Hst3 protein, putative; n=2;
Filobasidiella neoformans|Rep: Hst3 protein, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 389
Score = 41.9 bits (94), Expect = 0.012
Identities = 19/36 (52%), Positives = 26/36 (72%)
Frame = +1
Query: 352 VKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKE 459
V ++ IV +GAGIS S+GIPDFR G+++L KE
Sbjct: 32 VAKARRIVTVSGAGISCSSGIPDFRSEGGLYSLVKE 67
>UniRef50_Q4PG00 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 596
Score = 41.9 bits (94), Expect = 0.012
Identities = 19/40 (47%), Positives = 28/40 (70%), Gaps = 1/40 (2%)
Frame = +1
Query: 349 LVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWT-LEKEGK 465
L+ K I++ +GAGIS S GIPDFR +G++ L+ EG+
Sbjct: 186 LLSTRKRIMILSGAGISVSCGIPDFRSKDGIYAILQSEGQ 225
>UniRef50_Q9NXA8 Cluster: NAD-dependent deacetylase sirtuin-5; n=28;
Coelomata|Rep: NAD-dependent deacetylase sirtuin-5 -
Homo sapiens (Human)
Length = 310
Score = 41.9 bits (94), Expect = 0.012
Identities = 15/28 (53%), Positives = 21/28 (75%)
Frame = +1
Query: 361 SKHIVVHTGAGISTSAGIPDFRGPNGVW 444
+KHIV+ +GAG+S +G+P FRG G W
Sbjct: 50 AKHIVIISGAGVSAESGVPTFRGAGGYW 77
>UniRef50_Q8U1Q1 Cluster: NAD-dependent deacetylase; n=19; cellular
organisms|Rep: NAD-dependent deacetylase - Pyrococcus
furiosus
Length = 250
Score = 41.9 bits (94), Expect = 0.012
Identities = 28/104 (26%), Positives = 47/104 (45%), Gaps = 17/104 (16%)
Frame = +1
Query: 340 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW---------TLEKEGKKPTINVSF- 489
+++++ S + TGAGIS +GIP FRG +G+W T E + P + F
Sbjct: 5 VSKILAKSSMAIAFTGAGISAESGIPTFRGKDGLWRKYRAEELATPEAFKRDPKLVWEFY 64
Query: 490 -------ADAQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSG 600
+A+P H+ ++QN+D LH ++G
Sbjct: 65 KWRIKKILEAKPNPAHIALAELEKMGIIKAVITQNVDDLHREAG 108
>UniRef50_UPI00004997CB Cluster: Sir2 family transcriptional
regulator; n=2; Entamoeba histolytica HM-1:IMSS|Rep:
Sir2 family transcriptional regulator - Entamoeba
histolytica HM-1:IMSS
Length = 346
Score = 41.5 bits (93), Expect = 0.016
Identities = 40/123 (32%), Positives = 51/123 (41%), Gaps = 24/123 (19%)
Frame = +1
Query: 322 NQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGP-NGVW-TLE-------------- 453
N K L + ++VV GAGISTSAGIPDFR P G++ LE
Sbjct: 89 NAKGFGLFMKYRKPSNVVVMAGAGISTSAGIPDFRTPGTGLYDNLEAYNLPFPTAVFDIN 148
Query: 454 --KEGKKPTINVS------FADAQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSGVPR 609
K KP ++ PT TH +QNIDGL ++SG P
Sbjct: 149 YFKSNPKPFYTIASELMPGLGKYFPTPTHYFLTYLNKLGYISMLFTQNIDGLEIQSGFPN 208
Query: 610 KFL 618
+ L
Sbjct: 209 EKL 211
>UniRef50_A6Q2C0 Cluster: Transcriptional regulator, Sir2 family;
n=2; Bacteria|Rep: Transcriptional regulator, Sir2
family - Nitratiruptor sp. (strain SB155-2)
Length = 268
Score = 41.5 bits (93), Expect = 0.016
Identities = 15/40 (37%), Positives = 25/40 (62%)
Frame = +1
Query: 349 LVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKK 468
L+K + ++++ GAG+ +G+PDFRG +G W KK
Sbjct: 8 LIKQADYLLITAGAGMGVDSGLPDFRGVHGFWRAYPAAKK 47
>UniRef50_A4JJP4 Cluster: Silent information regulator protein Sir2;
n=1; Burkholderia vietnamiensis G4|Rep: Silent
information regulator protein Sir2 - Burkholderia
vietnamiensis (strain G4 / LMG 22486)
(Burkholderiacepacia (strain R1808))
Length = 273
Score = 41.5 bits (93), Expect = 0.016
Identities = 14/35 (40%), Positives = 24/35 (68%)
Frame = +1
Query: 343 AQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWT 447
A + ++ +++ GAG+S +G+PDFRG G+WT
Sbjct: 12 ASWIANADALIIAAGAGMSVDSGLPDFRGSQGIWT 46
>UniRef50_Q4QB33 Cluster: Sir2-family protein-like protein; n=4;
Trypanosomatidae|Rep: Sir2-family protein-like protein -
Leishmania major
Length = 320
Score = 41.5 bits (93), Expect = 0.016
Identities = 18/28 (64%), Positives = 21/28 (75%)
Frame = +1
Query: 355 KDSKHIVVHTGAGISTSAGIPDFRGPNG 438
K + VV TGAG ST +GIPD+RGPNG
Sbjct: 18 KRGRGCVVLTGAGCSTESGIPDYRGPNG 45
>UniRef50_Q2H5A0 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized
protein - Chaetomium globosum (Soil fungus)
Length = 387
Score = 41.5 bits (93), Expect = 0.016
Identities = 18/24 (75%), Positives = 21/24 (87%)
Frame = +1
Query: 361 SKHIVVHTGAGISTSAGIPDFRGP 432
++ IVV TGAGIST+AGIPDFR P
Sbjct: 34 ARRIVVMTGAGISTAAGIPDFRSP 57
>UniRef50_A5DNV7 Cluster: Putative uncharacterized protein; n=1;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 403
Score = 41.5 bits (93), Expect = 0.016
Identities = 20/39 (51%), Positives = 29/39 (74%), Gaps = 1/39 (2%)
Frame = +1
Query: 349 LVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWT-LEKEG 462
+++ +K I+V TGAGISTS GIPDFR G+++ L + G
Sbjct: 112 VLEKAKKILVVTGAGISTSLGIPDFRSFQGIYSQLSRSG 150
>UniRef50_O94640 Cluster: NAD-dependent histone deacetylase sir2;
n=1; Schizosaccharomyces pombe|Rep: NAD-dependent
histone deacetylase sir2 - Schizosaccharomyces pombe
(Fission yeast)
Length = 475
Score = 41.5 bits (93), Expect = 0.016
Identities = 19/35 (54%), Positives = 25/35 (71%)
Frame = +1
Query: 340 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 444
+ L+K +K++VV GAGISTS GI DFR NG +
Sbjct: 149 VVNLLKKAKNVVVLVGAGISTSLGILDFRSDNGFY 183
>UniRef50_Q875P9 Cluster: HST1; n=1; Lachancea kluyveri|Rep: HST1 -
Saccharomyces kluyveri (Yeast) (Saccharomyces
silvestris)
Length = 414
Score = 41.1 bits (92), Expect = 0.021
Identities = 18/35 (51%), Positives = 25/35 (71%)
Frame = +1
Query: 343 AQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWT 447
A +K ++ ++V TGAGISTS GIPDFR G ++
Sbjct: 77 AAKLKTARRVLVLTGAGISTSLGIPDFRSSEGFYS 111
>UniRef50_Q6C219 Cluster: Yarrowia lipolytica chromosome F of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome F of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 320
Score = 41.1 bits (92), Expect = 0.021
Identities = 23/53 (43%), Positives = 35/53 (66%)
Frame = +1
Query: 286 GVPEKFDSNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 444
G E ++ K++ LL +L + +++IVV GAGISTS GIPDFR +G++
Sbjct: 36 GDVESLAAHSKIHTFGDLLREL-ETAQNIVVLCGAGISTSLGIPDFRSADGLY 87
>UniRef50_Q88BY5 Cluster: NAD-dependent deacetylase; n=9;
Bacteria|Rep: NAD-dependent deacetylase - Pseudomonas
putida (strain KT2440)
Length = 262
Score = 41.1 bits (92), Expect = 0.021
Identities = 32/104 (30%), Positives = 47/104 (45%), Gaps = 18/104 (17%)
Frame = +1
Query: 343 AQLVKDSKHIVVHTGAGISTSAGIPDFRGP-NGVW---------TLEKEGKKPTINVSF- 489
A+ ++ SK +V TGAGIS +GIP FR G+W T + PT+ S+
Sbjct: 8 AEALRRSKTVVFFTGAGISADSGIPTFRDKLTGLWAKHDPQRLETADAFRANPTLVWSWY 67
Query: 490 -------ADAQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSG 600
+ A+P H+ V+QNID LH ++G
Sbjct: 68 LWRRHQVSQAKPNSAHLSIPQLADAGWDVSVVTQNIDDLHERAG 111
>UniRef50_Q21KQ1 Cluster: Silent information regulator protein Sir2;
n=2; Gammaproteobacteria|Rep: Silent information
regulator protein Sir2 - Saccharophagus degradans
(strain 2-40 / ATCC 43961 / DSM 17024)
Length = 235
Score = 40.7 bits (91), Expect = 0.027
Identities = 33/101 (32%), Positives = 42/101 (41%), Gaps = 19/101 (18%)
Frame = +1
Query: 355 KDSKHIVVHTGAGISTSAGIPDFRGPNGVW---------TLEKEGKKPTINVSFAD---- 495
KD K IVV TGAG+S +G+ FR NG+W T E + P + F +
Sbjct: 5 KDYKRIVVLTGAGVSAESGLKTFRDNNGLWENHRVEDVATPEAYARNPELVQKFYNARRS 64
Query: 496 -----AQPTKTH-MXXXXXXXXXXXXXXVSQNIDGLHLKSG 600
AQP K H V+QN+D LH G
Sbjct: 65 QLLTAAQPNKAHTALGEFEQHFSGEFLLVTQNVDNLHELGG 105
>UniRef50_A1ZHW6 Cluster: NAD-dependent deacetylase; n=2;
Microscilla marina ATCC 23134|Rep: NAD-dependent
deacetylase - Microscilla marina ATCC 23134
Length = 279
Score = 40.7 bits (91), Expect = 0.027
Identities = 18/38 (47%), Positives = 22/38 (57%)
Frame = +1
Query: 358 DSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKP 471
D +VV TGAGIS +GIP FRG G W + +P
Sbjct: 17 DQAKMVVLTGAGISAESGIPTFRGKEGYWKIGSVNYQP 54
>UniRef50_Q7QZ36 Cluster: GLP_464_21655_23334; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_464_21655_23334 - Giardia lamblia
ATCC 50803
Length = 559
Score = 40.7 bits (91), Expect = 0.027
Identities = 22/55 (40%), Positives = 34/55 (61%), Gaps = 4/55 (7%)
Frame = +1
Query: 352 VKDSKHIVVHTGAGISTSAGIPDFRGPNGVWT-LEKEG-KKPT--INVSFADAQP 504
++ ++ ++ GAGIS SAGIPDFR NG++ L++ +KPT N+ F P
Sbjct: 160 LRRARKVIFLVGAGISVSAGIPDFRSKNGIYNRLQQYNLQKPTDMFNLDFFRGNP 214
>UniRef50_A4QUX8 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 460
Score = 40.7 bits (91), Expect = 0.027
Identities = 18/23 (78%), Positives = 19/23 (82%)
Frame = +1
Query: 364 KHIVVHTGAGISTSAGIPDFRGP 432
K I V TGAGIST+AGIPDFR P
Sbjct: 40 KRITVMTGAGISTAAGIPDFRSP 62
>UniRef50_Q899G3 Cluster: NAD-dependent deacetylase; n=19; cellular
organisms|Rep: NAD-dependent deacetylase - Clostridium
tetani
Length = 247
Score = 40.7 bits (91), Expect = 0.027
Identities = 17/35 (48%), Positives = 24/35 (68%)
Frame = +1
Query: 340 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 444
L +L+K S +IV GAG+ST + IPDFR G++
Sbjct: 7 LKELIKSSSNIVFFGGAGVSTESNIPDFRSEEGLY 41
>UniRef50_Q81NT6 Cluster: NAD-dependent deacetylase; n=11; Bacillus
cereus group|Rep: NAD-dependent deacetylase - Bacillus
anthracis
Length = 242
Score = 40.7 bits (91), Expect = 0.027
Identities = 17/32 (53%), Positives = 24/32 (75%)
Frame = +1
Query: 349 LVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 444
+++ +K I V TGAG ST +GIPDFR NG++
Sbjct: 10 ILEKAKKITVLTGAGASTESGIPDFRSANGLY 41
>UniRef50_UPI00015B4FA0 Cluster: PREDICTED: similar to chromatin
regulatory protein sir2; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to chromatin regulatory protein sir2
- Nasonia vitripennis
Length = 736
Score = 40.3 bits (90), Expect = 0.036
Identities = 32/109 (29%), Positives = 43/109 (39%), Gaps = 21/109 (19%)
Frame = +1
Query: 337 LLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKPTINVSFADA------ 498
+L V S I V TGAGIST +GIPD+R GV ++P F +
Sbjct: 466 MLKHFVNTSGKICVITGAGISTESGIPDYRS-EGVGLFATSDRRPVSYQDFCKSDKTRRR 524
Query: 499 ---------------QPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSG 600
QP TH ++QN+D LH+K+G
Sbjct: 525 YWARNYAAWPRFSLFQPNVTHKWLKNMEDIGKVSCVITQNVDNLHIKAG 573
>UniRef50_UPI0000D578DC Cluster: PREDICTED: similar to sirtuin 5
(silent mating type information regulation 2 homolog) 5;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
sirtuin 5 (silent mating type information regulation 2
homolog) 5 - Tribolium castaneum
Length = 254
Score = 40.3 bits (90), Expect = 0.036
Identities = 16/33 (48%), Positives = 23/33 (69%)
Frame = +1
Query: 346 QLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 444
++V ++ IV TGAG+S +GIP FRG G+W
Sbjct: 14 RVVSQARSIVALTGAGVSAESGIPVFRGAGGLW 46
>UniRef50_UPI00006CA40C Cluster: transcriptional regulator, Sir2
family protein; n=1; Tetrahymena thermophila SB210|Rep:
transcriptional regulator, Sir2 family protein -
Tetrahymena thermophila SB210
Length = 471
Score = 40.3 bits (90), Expect = 0.036
Identities = 37/105 (35%), Positives = 47/105 (44%), Gaps = 22/105 (20%)
Frame = +1
Query: 370 IVVHTGAGISTSAGIPDFRGP-NGVWTLEKEGKKP------TINVSFADAQP-------- 504
IV TGAGIS SAGIPDFR P +G+++ ++ K P IN QP
Sbjct: 214 IVFLTGAGISVSAGIPDFRTPGSGLYSQLQKYKLPYPEAIFEINYFKHHPQPFYTLCKEF 273
Query: 505 -------TKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSGVPRKFL 618
T +H SQNIDGL L++G+P L
Sbjct: 274 SSCGSHFTSSHFFIAETNRRNRLLINFSQNIDGLELEAGLPESKL 318
>UniRef50_A6WG46 Cluster: Silent information regulator protein Sir2;
n=4; Actinomycetales|Rep: Silent information regulator
protein Sir2 - Kineococcus radiotolerans SRS30216
Length = 279
Score = 40.3 bits (90), Expect = 0.036
Identities = 33/104 (31%), Positives = 46/104 (44%), Gaps = 17/104 (16%)
Frame = +1
Query: 340 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGV-----------WTLEKEGKKPTINVS 486
LA L+ D +VV GAG+ST +GIPD+RGP G +T E ++ S
Sbjct: 7 LADLL-DGGRVVVLEGAGMSTGSGIPDYRGPGGSLQRHTPMTYQEFTGSAEARRRYWGRS 65
Query: 487 ------FADAQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSG 600
F A+P H ++QN+DGL L +G
Sbjct: 66 HVGWEHFRRARPNDAHRAVAALEGAGVVTGVITQNVDGLDLAAG 109
>UniRef50_Q1EP52 Cluster: Transcriptional regulator Sir2 family
protein; n=1; Musa balbisiana|Rep: Transcriptional
regulator Sir2 family protein - Musa balbisiana (Banana)
Length = 217
Score = 40.3 bits (90), Expect = 0.036
Identities = 18/30 (60%), Positives = 23/30 (76%)
Frame = +1
Query: 337 LLAQLVKDSKHIVVHTGAGISTSAGIPDFR 426
LL Q + S+ +VV TGAGIST +GIPD+R
Sbjct: 175 LLYQFIDTSRKLVVLTGAGISTESGIPDYR 204
>UniRef50_Q54QE6 Cluster: Zn finger-containing protein; n=5;
Eukaryota|Rep: Zn finger-containing protein -
Dictyostelium discoideum AX4
Length = 512
Score = 40.3 bits (90), Expect = 0.036
Identities = 17/23 (73%), Positives = 20/23 (86%)
Frame = +1
Query: 364 KHIVVHTGAGISTSAGIPDFRGP 432
K+I+V TGAGIS +AGIPDFR P
Sbjct: 251 KNIIVMTGAGISVAAGIPDFRSP 273
>UniRef50_Q9USN7 Cluster: Sir2 family histone deacetylase Hst2; n=1;
Schizosaccharomyces pombe|Rep: Sir2 family histone
deacetylase Hst2 - Schizosaccharomyces pombe (Fission
yeast)
Length = 332
Score = 40.3 bits (90), Expect = 0.036
Identities = 20/33 (60%), Positives = 24/33 (72%), Gaps = 2/33 (6%)
Frame = +1
Query: 340 LAQLVKDSK--HIVVHTGAGISTSAGIPDFRGP 432
+A L+K+ K I V GAGIST+AGIPDFR P
Sbjct: 18 VASLIKEGKVKKICVMVGAGISTAAGIPDFRSP 50
>UniRef50_Q5KG84 Cluster: Hst4 protein, putative; n=2;
Filobasidiella neoformans|Rep: Hst4 protein, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 478
Score = 40.3 bits (90), Expect = 0.036
Identities = 23/53 (43%), Positives = 36/53 (67%)
Frame = +1
Query: 304 DSNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEG 462
D D L Q ++A+L + +K IVV +GAG+ST A IPDFR +G+++ + +G
Sbjct: 28 DVEDTLRQ---VVARL-RMAKRIVVVSGAGVSTGAAIPDFRSASGLFSGKTKG 76
>UniRef50_Q2HG51 Cluster: Putative uncharacterized protein; n=2;
Pezizomycotina|Rep: Putative uncharacterized protein -
Chaetomium globosum (Soil fungus)
Length = 594
Score = 40.3 bits (90), Expect = 0.036
Identities = 24/54 (44%), Positives = 29/54 (53%), Gaps = 1/54 (1%)
Frame = +1
Query: 352 VKDSKHIVVHTGAGISTSAGIPDFRGPNGVW-TLEKEGKKPTINVSFADAQPTK 510
++ K IVV GAGIS SAGIPDFR G++ TL + K DA K
Sbjct: 46 LRKKKKIVVIAGAGISVSAGIPDFRSSTGLFATLRGQHKLKASGKHLFDASVYK 99
>UniRef50_A3LRA1 Cluster: Transcriptional regulatory protein; n=2;
Saccharomycetales|Rep: Transcriptional regulatory
protein - Pichia stipitis (Yeast)
Length = 311
Score = 40.3 bits (90), Expect = 0.036
Identities = 16/42 (38%), Positives = 27/42 (64%)
Frame = +1
Query: 319 LNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 444
++++ V + +K + IV GAG+S S+G+P FRG G+W
Sbjct: 1 MSKQLVEFQEYLKTCRKIVALVGAGLSVSSGLPTFRGSQGLW 42
>UniRef50_A1CD03 Cluster: SIR2 family histone deacetylase, putative;
n=2; Trichocomaceae|Rep: SIR2 family histone
deacetylase, putative - Aspergillus clavatus
Length = 329
Score = 40.3 bits (90), Expect = 0.036
Identities = 20/33 (60%), Positives = 24/33 (72%), Gaps = 2/33 (6%)
Frame = +1
Query: 340 LAQLVKDS--KHIVVHTGAGISTSAGIPDFRGP 432
+A L+K + IVV GAGIST+AGIPDFR P
Sbjct: 7 IATLIKSGQIRRIVVLVGAGISTAAGIPDFRSP 39
>UniRef50_Q607X6 Cluster: NAD-dependent deacetylase; n=1;
Methylococcus capsulatus|Rep: NAD-dependent deacetylase
- Methylococcus capsulatus
Length = 255
Score = 40.3 bits (90), Expect = 0.036
Identities = 20/37 (54%), Positives = 25/37 (67%), Gaps = 1/37 (2%)
Frame = +1
Query: 337 LLAQLVKDSKHIVVHTGAGISTSAGIPDFRGP-NGVW 444
LLA L +D++HI V TGAG+S +GIP FR G W
Sbjct: 7 LLASL-RDARHIAVFTGAGVSAESGIPTFRDALTGFW 42
>UniRef50_P53688 Cluster: NAD-dependent histone deacetylase HST4;
n=5; Saccharomycetales|Rep: NAD-dependent histone
deacetylase HST4 - Saccharomyces cerevisiae (Baker's
yeast)
Length = 370
Score = 40.3 bits (90), Expect = 0.036
Identities = 18/34 (52%), Positives = 24/34 (70%)
Frame = +1
Query: 361 SKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEG 462
SK +VV +GAGIS +AGIPDFR G+++ G
Sbjct: 92 SKRMVVVSGAGISVAAGIPDFRSSEGIFSTVNGG 125
>UniRef50_UPI0000519F58 Cluster: PREDICTED: similar to Sirt4
CG3187-PC, isoform C isoform 2; n=2; Endopterygota|Rep:
PREDICTED: similar to Sirt4 CG3187-PC, isoform C isoform
2 - Apis mellifera
Length = 302
Score = 39.9 bits (89), Expect = 0.047
Identities = 30/108 (27%), Positives = 43/108 (39%), Gaps = 21/108 (19%)
Frame = +1
Query: 340 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKPTINVSFADA------- 498
L + +I V TGAGIST +GIPD+R GV + KP + F ++
Sbjct: 33 LKDFIDSHDNICVLTGAGISTESGIPDYRS-EGVGLYARSNHKPVLYKDFCNSDAIRRRY 91
Query: 499 --------------QPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSG 600
+P TH ++QN+D LH K+G
Sbjct: 92 WARNYIGWPRFSSIKPNNTHKILTKLENANKIRYIITQNVDNLHTKAG 139
>UniRef50_A1FG80 Cluster: Silent information regulator protein Sir2;
n=3; Pseudomonas|Rep: Silent information regulator
protein Sir2 - Pseudomonas putida W619
Length = 252
Score = 39.9 bits (89), Expect = 0.047
Identities = 29/104 (27%), Positives = 45/104 (43%), Gaps = 18/104 (17%)
Frame = +1
Query: 343 AQLVKDSKHIVVHTGAGISTSAGIPDFRGP-NGVW---------TLEKEGKKPTI----- 477
A+ ++ ++HI+V TGAG+S +GIP FR G+W T + + P +
Sbjct: 8 AEALRSAQHIMVFTGAGVSAGSGIPTFRDELTGLWERQDPQRLETAQAFRENPALVWGWY 67
Query: 478 ---NVSFADAQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSG 600
A+P H V+QNID LH ++G
Sbjct: 68 LWRRQQVMQAKPNAAHQAIHRLSGSGRSVTVVTQNIDDLHERAG 111
>UniRef50_Q22ZC3 Cluster: Transcriptional regulator, Sir2 family
protein; n=1; Tetrahymena thermophila SB210|Rep:
Transcriptional regulator, Sir2 family protein -
Tetrahymena thermophila SB210
Length = 308
Score = 39.9 bits (89), Expect = 0.047
Identities = 19/28 (67%), Positives = 19/28 (67%)
Frame = +1
Query: 349 LVKDSKHIVVHTGAGISTSAGIPDFRGP 432
L K K I TGAGIS SAGIPDFR P
Sbjct: 63 LAKKYKQIAFLTGAGISVSAGIPDFRSP 90
>UniRef50_A0DQW0 Cluster: Chromosome undetermined scaffold_6, whole
genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_6,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 367
Score = 39.9 bits (89), Expect = 0.047
Identities = 17/52 (32%), Positives = 31/52 (59%)
Frame = +1
Query: 304 DSNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKE 459
+ N K Q+ + +K++++ GAG+S ++G+P FRG +G WT K+
Sbjct: 101 EQNPKTAQEVTVEQAQKLITKNVLILCGAGLSHASGVPTFRGKDGYWTKGKD 152
>UniRef50_Q6BVM7 Cluster: Similar to CA4170|IPF7784 Candida
albicans; n=2; Saccharomycetaceae|Rep: Similar to
CA4170|IPF7784 Candida albicans - Debaryomyces hansenii
(Yeast) (Torulaspora hansenii)
Length = 301
Score = 39.9 bits (89), Expect = 0.047
Identities = 30/104 (28%), Positives = 49/104 (47%), Gaps = 18/104 (17%)
Frame = +1
Query: 361 SKHIVVHTGAGISTSAGIPDFRGPNGVW---------TLEKEGKKPTI--------NVSF 489
SK IV GAG+S S+G+P FRG G+W T + P + ++
Sbjct: 15 SKRIVALVGAGLSVSSGLPTFRGSQGLWKNFNMIDLATPDAFYIDPGLVWQFYSWRRINA 74
Query: 490 ADAQPTKTHMXXXXXXXXXXXXXX-VSQNIDGLHLKSGVPRKFL 618
+ A+P K H+ ++QN+DGL +++G P++ L
Sbjct: 75 SKAKPNKGHLALAKLSKLSNIEFMTITQNVDGLLIRAGHPKEKL 118
>UniRef50_Q4WFZ3 Cluster: SIR2 family histone deacetylase, putative;
n=4; Trichocomaceae|Rep: SIR2 family histone
deacetylase, putative - Aspergillus fumigatus (Sartorya
fumigata)
Length = 403
Score = 39.9 bits (89), Expect = 0.047
Identities = 20/33 (60%), Positives = 24/33 (72%), Gaps = 2/33 (6%)
Frame = +1
Query: 340 LAQLVKDSK--HIVVHTGAGISTSAGIPDFRGP 432
+A L+K + IVV GAGIST+AGIPDFR P
Sbjct: 83 IANLIKSGQVHKIVVLVGAGISTAAGIPDFRSP 115
>UniRef50_Q4P3S4 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 400
Score = 39.9 bits (89), Expect = 0.047
Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 1/62 (1%)
Frame = +1
Query: 337 LLAQLVKDSK-HIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKPTINVSFADAQPTKT 513
L+A+ V +K ++ TGAGIS +GI +RG NG +T+ K +P F DA K
Sbjct: 27 LVAEFVSAAKGKALIMTGAGISVDSGIAPYRGENGHYTIHKH-YRPIFYHEFVDAS-DKG 84
Query: 514 HM 519
H+
Sbjct: 85 HL 86
>UniRef50_Q7ZVK3 Cluster: NAD-dependent deacetylase sirtuin-2; n=12;
Coelomata|Rep: NAD-dependent deacetylase sirtuin-2 -
Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 379
Score = 39.9 bits (89), Expect = 0.047
Identities = 21/40 (52%), Positives = 24/40 (60%)
Frame = +1
Query: 313 DKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGP 432
D+L V L K+I+ GAGISTSAGIPDFR P
Sbjct: 58 DELTLDSVARYILSGKCKNIICMVGAGISTSAGIPDFRSP 97
>UniRef50_P53687 Cluster: NAD-dependent histone deacetylase HST3;
n=6; Saccharomycetales|Rep: NAD-dependent histone
deacetylase HST3 - Saccharomyces cerevisiae (Baker's
yeast)
Length = 447
Score = 39.9 bits (89), Expect = 0.047
Identities = 18/33 (54%), Positives = 24/33 (72%)
Frame = +1
Query: 361 SKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKE 459
S+ I TGAGIS +AGIPDFR +G++ L K+
Sbjct: 52 SRRIACLTGAGISCNAGIPDFRSSDGLYDLVKK 84
>UniRef50_UPI00015B48CB Cluster: PREDICTED: similar to 85 kda
calcium-independent phospholipase A2 (ipla2); n=1;
Nasonia vitripennis|Rep: PREDICTED: similar to 85 kda
calcium-independent phospholipase A2 (ipla2) - Nasonia
vitripennis
Length = 811
Score = 39.5 bits (88), Expect = 0.063
Identities = 20/54 (37%), Positives = 30/54 (55%)
Frame = +1
Query: 304 DSNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGK 465
D + L +KC+ LA + +V + A IS + IPD+RG NG+W + GK
Sbjct: 65 DIPEILEEKCIRLAAAISRETSLV-YIVADISIAVSIPDYRGINGMWARMQLGK 117
>UniRef50_UPI000023E2DA Cluster: hypothetical protein FG00460.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG00460.1 - Gibberella zeae PH-1
Length = 607
Score = 39.5 bits (88), Expect = 0.063
Identities = 19/39 (48%), Positives = 24/39 (61%)
Frame = +1
Query: 340 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEK 456
L ++ K IVV GAGIS +AGIPDFR G++ K
Sbjct: 123 LRDTLRKKKKIVVIAGAGISVAAGIPDFRSSTGLFASVK 161
>UniRef50_Q1QTH0 Cluster: Silent information regulator protein Sir2;
n=2; Oceanospirillales|Rep: Silent information regulator
protein Sir2 - Chromohalobacter salexigens (strain DSM
3043 / ATCC BAA-138 / NCIMB13768)
Length = 242
Score = 39.5 bits (88), Expect = 0.063
Identities = 29/95 (30%), Positives = 41/95 (43%), Gaps = 17/95 (17%)
Frame = +1
Query: 367 HIVVHTGAGISTSAGIPDFRGPNGVW---------TLEKEGKKPTINVSFADAQ------ 501
H+VV TGAGIS +G+ FR +G+W T E + P + F DA+
Sbjct: 8 HLVVLTGAGISAESGLKTFRDGDGLWENHRVQDVATPEAFARDPETVLRFYDARREQTRQ 67
Query: 502 --PTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSG 600
P H ++QNID LH ++G
Sbjct: 68 ATPNAAHRALAELEQAGFQVSVITQNIDDLHERAG 102
>UniRef50_A6LP94 Cluster: Silent information regulator protein Sir2;
n=1; Thermosipho melanesiensis BI429|Rep: Silent
information regulator protein Sir2 - Thermosipho
melanesiensis BI429
Length = 234
Score = 39.5 bits (88), Expect = 0.063
Identities = 16/31 (51%), Positives = 24/31 (77%)
Frame = +1
Query: 352 VKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 444
+ + ++V TGAGISTS+GIPDFR +G++
Sbjct: 8 ILEEGNVVALTGAGISTSSGIPDFRSEDGLY 38
>UniRef50_Q8IRR5 Cluster: CG3187-PC, isoform C; n=4; Diptera|Rep:
CG3187-PC, isoform C - Drosophila melanogaster (Fruit
fly)
Length = 312
Score = 39.5 bits (88), Expect = 0.063
Identities = 31/108 (28%), Positives = 44/108 (40%), Gaps = 21/108 (19%)
Frame = +1
Query: 340 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKPTINVSFADA------- 498
L + +++V TGAGIST +GIPD+R GV + KP ++ F +
Sbjct: 38 LEDFLLSKPNVLVLTGAGISTESGIPDYRS-EGVGLYARSNHKPVQHMEFVKSSAVRKRY 96
Query: 499 --------------QPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSG 600
QP TH V+QN+D LH K+G
Sbjct: 97 WARNFVGWPKFSATQPNATHHALARFEREERVQAVVTQNVDRLHTKAG 144
>UniRef50_Q23YS7 Cluster: Transcriptional regulator, Sir2 family
protein; n=1; Tetrahymena thermophila SB210|Rep:
Transcriptional regulator, Sir2 family protein -
Tetrahymena thermophila SB210
Length = 304
Score = 39.5 bits (88), Expect = 0.063
Identities = 13/36 (36%), Positives = 24/36 (66%)
Frame = +1
Query: 337 LLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 444
L+A+ ++ + +++ GAG+ +G+PDFRG G W
Sbjct: 8 LIAKRIQSASCLIITAGAGMGVDSGLPDFRGKEGFW 43
>UniRef50_A1CTI6 Cluster: SIR2 family histone deacetylase, putative;
n=8; Eurotiomycetidae|Rep: SIR2 family histone
deacetylase, putative - Aspergillus clavatus
Length = 320
Score = 39.5 bits (88), Expect = 0.063
Identities = 15/33 (45%), Positives = 22/33 (66%)
Frame = +1
Query: 346 QLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 444
+ +K K I+ GAG+S S+G+P FRG G+W
Sbjct: 16 EYLKGCKRIIALCGAGLSASSGLPTFRGAGGLW 48
>UniRef50_Q8R216 Cluster: NAD-dependent deacetylase sirtuin-4; n=7;
cellular organisms|Rep: NAD-dependent deacetylase
sirtuin-4 - Mus musculus (Mouse)
Length = 333
Score = 39.5 bits (88), Expect = 0.063
Identities = 20/62 (32%), Positives = 34/62 (54%)
Frame = +1
Query: 325 QKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKPTINVSFADAQP 504
+K L + + SK ++V TGAGIST + IPD+R V + ++P ++ F + P
Sbjct: 39 EKIKELQRFISLSKKLLVMTGAGISTESSIPDYRSEK-VGLYARTDRRPIQHIDFVRSAP 97
Query: 505 TK 510
+
Sbjct: 98 VR 99
>UniRef50_O59923 Cluster: NAD-dependent histone deacetylase SIR2;
n=3; Candida albicans|Rep: NAD-dependent histone
deacetylase SIR2 - Candida albicans (Yeast)
Length = 515
Score = 39.5 bits (88), Expect = 0.063
Identities = 21/38 (55%), Positives = 26/38 (68%), Gaps = 3/38 (7%)
Frame = +1
Query: 340 LAQLVKD---SKHIVVHTGAGISTSAGIPDFRGPNGVW 444
L L+ D +K I+V TGAGISTS GIPDFR G++
Sbjct: 224 LPDLISDLSRAKKIMVVTGAGISTSLGIPDFRSFKGLY 261
>UniRef50_A4A980 Cluster: NAD-dependent deacetylase; n=5;
Gammaproteobacteria|Rep: NAD-dependent deacetylase -
Congregibacter litoralis KT71
Length = 241
Score = 39.1 bits (87), Expect = 0.083
Identities = 15/30 (50%), Positives = 19/30 (63%)
Frame = +1
Query: 382 TGAGISTSAGIPDFRGPNGVWTLEKEGKKP 471
TGAG+S +GIP FRG +G WT+ P
Sbjct: 7 TGAGVSAESGIPTFRGEDGFWTIGSRNYTP 36
>UniRef50_A1I9S7 Cluster: NAD-dependent deacetylase; n=1; Candidatus
Desulfococcus oleovorans Hxd3|Rep: NAD-dependent
deacetylase - Candidatus Desulfococcus oleovorans Hxd3
Length = 273
Score = 39.1 bits (87), Expect = 0.083
Identities = 15/34 (44%), Positives = 22/34 (64%)
Frame = +1
Query: 343 AQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 444
A+++ + V +GAG+S +GIP FR P GVW
Sbjct: 11 AKVLAGASRAAVFSGAGVSAESGIPTFRDPGGVW 44
>UniRef50_Q7PS76 Cluster: ENSANGP00000025231; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000025231 - Anopheles gambiae
str. PEST
Length = 182
Score = 39.1 bits (87), Expect = 0.083
Identities = 20/47 (42%), Positives = 28/47 (59%)
Frame = +1
Query: 370 IVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKPTINVSFADAQPTK 510
I+V TGAGIST +GIPD+R GV + KP + F ++ T+
Sbjct: 1 ILVLTGAGISTESGIPDYRS-EGVGLYARSNHKPIQHGDFVKSEATR 46
>UniRef50_Q54P49 Cluster: Zn finger-containing protein; n=1;
Dictyostelium discoideum AX4|Rep: Zn finger-containing
protein - Dictyostelium discoideum AX4
Length = 456
Score = 39.1 bits (87), Expect = 0.083
Identities = 25/70 (35%), Positives = 40/70 (57%), Gaps = 4/70 (5%)
Frame = +1
Query: 268 ENKGILGVPEKFDSNDKL-NQKCVLLAQLVKDSK--HIVVHTGAGISTSAGIPDFRG-PN 435
+N I+ K ++ ++ N K +L+K+ K +I+V TGAGIS ++GIPDFR
Sbjct: 146 KNSNIIKNEIKIENEIEIENNKIKEFIKLIKNDKCKNIIVLTGAGISVASGIPDFRSVET 205
Query: 436 GVWTLEKEGK 465
G++ E K
Sbjct: 206 GLYNNENVSK 215
>UniRef50_Q298C7 Cluster: GA18650-PA; n=1; Drosophila
pseudoobscura|Rep: GA18650-PA - Drosophila pseudoobscura
(Fruit fly)
Length = 381
Score = 39.1 bits (87), Expect = 0.083
Identities = 17/23 (73%), Positives = 18/23 (78%)
Frame = +1
Query: 364 KHIVVHTGAGISTSAGIPDFRGP 432
K I+ GAGISTSAGIPDFR P
Sbjct: 76 KKIITMVGAGISTSAGIPDFRSP 98
>UniRef50_Q5KDE0 Cluster: NAD-dependent histone deacetylase,
putative; n=2; Filobasidiella neoformans|Rep:
NAD-dependent histone deacetylase, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 413
Score = 39.1 bits (87), Expect = 0.083
Identities = 23/52 (44%), Positives = 31/52 (59%), Gaps = 2/52 (3%)
Frame = +1
Query: 286 GVPEKFDSNDKLNQKCVLLAQLVK--DSKHIVVHTGAGISTSAGIPDFRGPN 435
G+ + S D LN A +K ++K ++ GAGISTSAGIPDFR P+
Sbjct: 46 GIDDGALSGDDLNP-LRKAASFIKSGNAKDVIFLLGAGISTSAGIPDFRSPS 96
>UniRef50_Q9Y6E7 Cluster: NAD-dependent deacetylase sirtuin-4; n=23;
Deuterostomia|Rep: NAD-dependent deacetylase sirtuin-4 -
Homo sapiens (Human)
Length = 314
Score = 39.1 bits (87), Expect = 0.083
Identities = 21/62 (33%), Positives = 34/62 (54%)
Frame = +1
Query: 325 QKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKPTINVSFADAQP 504
+K L + + SK ++V TGAGIST +GIPD+R V + ++P + F + P
Sbjct: 42 EKVKELQRFITLSKRLLVMTGAGISTESGIPDYRSEK-VGLYARTDRRPIQHGDFVRSAP 100
Query: 505 TK 510
+
Sbjct: 101 IR 102
>UniRef50_P06700 Cluster: NAD-dependent histone deacetylase SIR2;
n=13; Saccharomycetales|Rep: NAD-dependent histone
deacetylase SIR2 - Saccharomyces cerevisiae (Baker's
yeast)
Length = 562
Score = 39.1 bits (87), Expect = 0.083
Identities = 17/34 (50%), Positives = 24/34 (70%)
Frame = +1
Query: 346 QLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWT 447
Q + ++ I+V TGAG+STS GIPDFR G ++
Sbjct: 249 QKLHTARKILVLTGAGVSTSLGIPDFRSSEGFYS 282
>UniRef50_Q839C6 Cluster: NAD-dependent deacetylase; n=14;
Bacilli|Rep: NAD-dependent deacetylase - Enterococcus
faecalis (Streptococcus faecalis)
Length = 237
Score = 39.1 bits (87), Expect = 0.083
Identities = 32/89 (35%), Positives = 42/89 (47%), Gaps = 16/89 (17%)
Frame = +1
Query: 382 TGAGISTSAGIPDFRGPNGVW-------------TLEKEGKK--PTINVSF-ADAQPTKT 513
TGAGIST++G+PD+R GV+ L+ E +K + + DAQP
Sbjct: 23 TGAGISTASGVPDYRSLKGVYQGIQQPEYLLSRTCLKTEPEKFYQFVKTLYHPDAQPNII 82
Query: 514 HMXXXXXXXXXXXXXXVSQNIDGLHLKSG 600
H VSQNIDGLH K+G
Sbjct: 83 HQ-KMAQLEQMKRGKIVSQNIDGLHRKAG 110
>UniRef50_Q885X7 Cluster: NAD-dependent deacetylase 2; n=4;
Pseudomonas|Rep: NAD-dependent deacetylase 2 -
Pseudomonas syringae pv. tomato
Length = 248
Score = 39.1 bits (87), Expect = 0.083
Identities = 17/43 (39%), Positives = 27/43 (62%)
Frame = +1
Query: 343 AQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKP 471
A ++ +K I+V TGAG+S +G+P +RG G++ E E P
Sbjct: 5 ASALRHAKRILVITGAGLSADSGLPTYRGVGGLYNGETEDGLP 47
>UniRef50_UPI000050FCF4 Cluster: COG0846: NAD-dependent protein
deacetylases, SIR2 family; n=1; Brevibacterium linens
BL2|Rep: COG0846: NAD-dependent protein deacetylases,
SIR2 family - Brevibacterium linens BL2
Length = 309
Score = 38.7 bits (86), Expect = 0.11
Identities = 21/51 (41%), Positives = 30/51 (58%), Gaps = 1/51 (1%)
Frame = +1
Query: 292 PEKFDSNDKLNQKCVLLAQLVK-DSKHIVVHTGAGISTSAGIPDFRGPNGV 441
PE S+D++ A V D+ V TGAG+ST +G+PD+RGP+ V
Sbjct: 14 PEPSHSDDEIIDVLTGTAGAVGIDTSGWAVLTGAGMSTDSGVPDYRGPDAV 64
>UniRef50_Q4S7H2 Cluster: Chromosome 13 SCAF14715, whole genome
shotgun sequence; n=6; Clupeocephala|Rep: Chromosome 13
SCAF14715, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 327
Score = 38.7 bits (86), Expect = 0.11
Identities = 22/47 (46%), Positives = 33/47 (70%), Gaps = 3/47 (6%)
Frame = +1
Query: 340 LAQLVK--DSKHIVVHTGAGISTSAGIPDFRGP-NGVWTLEKEGKKP 471
+A+LVK +++VV GAGIST++GIPDFR P G++ ++ K P
Sbjct: 39 VARLVKLGRCRNVVVVAGAGISTASGIPDFRTPGTGLYANLEQYKLP 85
>UniRef50_Q6AF12 Cluster: Regulatory protein, Sir2 family; n=2;
Actinobacteria (class)|Rep: Regulatory protein, Sir2
family - Leifsonia xyli subsp. xyli
Length = 283
Score = 38.7 bits (86), Expect = 0.11
Identities = 31/101 (30%), Positives = 42/101 (41%), Gaps = 15/101 (14%)
Frame = +1
Query: 352 VKDSKHIVVHTGAGISTSAGIPDFRGPNG---------VWTLEKEGKKPTINVS------ 486
V + V TGAG+ST +GIPD+RG + E +K S
Sbjct: 24 VLSGRRFAVLTGAGVSTDSGIPDYRGEGAPKRTPMTFQQFLAEDRHRKRYWAGSHLGYRR 83
Query: 487 FADAQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSGVPR 609
F+ A+P H V+QN+DGLH K+G R
Sbjct: 84 FSAARPNDGHRALAALEDAGAAAGVVTQNVDGLHKKAGSRR 124
>UniRef50_Q03ZB1 Cluster: NAD-dependent protein deacetylase, SIR2
family; n=3; Leuconostocaceae|Rep: NAD-dependent protein
deacetylase, SIR2 family - Leuconostoc mesenteroides
subsp. mesenteroides (strain ATCC 8293 /NCDO 523)
Length = 234
Score = 38.7 bits (86), Expect = 0.11
Identities = 15/29 (51%), Positives = 23/29 (79%)
Frame = +1
Query: 358 DSKHIVVHTGAGISTSAGIPDFRGPNGVW 444
++K+IV TGAG+ST +GIPD+R G++
Sbjct: 13 NAKNIVFMTGAGVSTLSGIPDYRSKGGIY 41
>UniRef50_A0PU12 Cluster: Sir2-like regulatory protein; n=1;
Mycobacterium ulcerans Agy99|Rep: Sir2-like regulatory
protein - Mycobacterium ulcerans (strain Agy99)
Length = 283
Score = 38.7 bits (86), Expect = 0.11
Identities = 28/92 (30%), Positives = 38/92 (41%), Gaps = 15/92 (16%)
Frame = +1
Query: 370 IVVHTGAGISTSAGIPDFRGPNGV----WTLEKEGKKPTINVSF-----------ADAQP 504
I V TGAGIST +GIPD+RGP+ T+ + P + D P
Sbjct: 15 IAVLTGAGISTDSGIPDYRGPDSPPSNPMTIRQFTSDPVFRQRYWARNHVGWRHMDDTAP 74
Query: 505 TKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSG 600
H ++QN+D LH K+G
Sbjct: 75 NAGHRALAALERAGVVTGVITQNVDLLHTKAG 106
>UniRef50_Q8SSB6 Cluster: SIR2-LIKE PROTEIN INVOLVED IN TELOMERIC
SILENCING; n=1; Encephalitozoon cuniculi|Rep: SIR2-LIKE
PROTEIN INVOLVED IN TELOMERIC SILENCING -
Encephalitozoon cuniculi
Length = 425
Score = 38.7 bits (86), Expect = 0.11
Identities = 16/27 (59%), Positives = 22/27 (81%)
Frame = +1
Query: 364 KHIVVHTGAGISTSAGIPDFRGPNGVW 444
+ +VV TGAGIS S+GIPDFR +G++
Sbjct: 86 RRVVVITGAGISVSSGIPDFRSKSGLF 112
>UniRef50_Q750H1 Cluster: AGL018Cp; n=1; Eremothecium gossypii|Rep:
AGL018Cp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 340
Score = 38.7 bits (86), Expect = 0.11
Identities = 21/42 (50%), Positives = 25/42 (59%), Gaps = 1/42 (2%)
Frame = +1
Query: 370 IVVHTGAGISTSAGIPDFRGPN-GVWTLEKEGKKPTINVSFA 492
+V GAGISTS GIPDFR PN G++ + K P FA
Sbjct: 24 VVFLVGAGISTSCGIPDFRSPNTGLYHNLSKFKLPYAEAVFA 65
>UniRef50_A5DJ74 Cluster: Putative uncharacterized protein; n=1;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 522
Score = 38.7 bits (86), Expect = 0.11
Identities = 17/31 (54%), Positives = 23/31 (74%)
Frame = +1
Query: 352 VKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 444
++ +K I+V +GAGISTS GIPDFR G +
Sbjct: 206 LQSAKKILVLSGAGISTSLGIPDFRSSQGFY 236
>UniRef50_A4RCT8 Cluster: Putative uncharacterized protein; n=3;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 1040
Score = 38.7 bits (86), Expect = 0.11
Identities = 15/28 (53%), Positives = 21/28 (75%)
Frame = +1
Query: 361 SKHIVVHTGAGISTSAGIPDFRGPNGVW 444
S++IV GAG+S S+G+ FRGP G+W
Sbjct: 33 SRNIVAIIGAGLSASSGLATFRGPGGLW 60
>UniRef50_Q7WLE5 Cluster: NAD-dependent deacetylase; n=47;
Bacteria|Rep: NAD-dependent deacetylase - Bordetella
bronchiseptica (Alcaligenes bronchisepticus)
Length = 274
Score = 38.7 bits (86), Expect = 0.11
Identities = 21/51 (41%), Positives = 30/51 (58%), Gaps = 1/51 (1%)
Frame = +1
Query: 361 SKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKPTINV-SFADAQPTK 510
S+ + V TGAG ST++GIPD+R G W +KP I+ +F QP +
Sbjct: 18 SERLFVLTGAGCSTASGIPDYRDGQGQWK-----RKPPIDFQAFMGGQPAR 63
>UniRef50_A7HID4 Cluster: Silent information regulator protein Sir2;
n=9; Deltaproteobacteria|Rep: Silent information
regulator protein Sir2 - Anaeromyxobacter sp. Fw109-5
Length = 289
Score = 38.3 bits (85), Expect = 0.14
Identities = 18/52 (34%), Positives = 29/52 (55%)
Frame = +1
Query: 343 AQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKPTINVSFADA 498
A ++ + +VV GAG+ +G+PDFRG G W ++ + +SF DA
Sbjct: 9 AAALRSAGALVVTAGAGMGVDSGLPDFRGDQGFWKAYPPYER--LGLSFVDA 58
>UniRef50_A7H7B6 Cluster: Silent information regulator protein Sir2;
n=2; Anaeromyxobacter|Rep: Silent information regulator
protein Sir2 - Anaeromyxobacter sp. Fw109-5
Length = 270
Score = 38.3 bits (85), Expect = 0.14
Identities = 17/45 (37%), Positives = 23/45 (51%)
Frame = +1
Query: 337 LLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKP 471
LL + + +V TGAG+S +GIP FRG G W + P
Sbjct: 8 LLDDVRRAQGRVVALTGAGVSAESGIPTFRGREGFWVVGSRNYMP 52
>UniRef50_A2DKF0 Cluster: Transcriptional regulator, Sir2 family
protein; n=1; Trichomonas vaginalis G3|Rep:
Transcriptional regulator, Sir2 family protein -
Trichomonas vaginalis G3
Length = 347
Score = 38.3 bits (85), Expect = 0.14
Identities = 19/42 (45%), Positives = 29/42 (69%), Gaps = 1/42 (2%)
Frame = +1
Query: 340 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW-TLEKEG 462
+ +L+++SKHI+V GAG S PDFR P G++ ++ KEG
Sbjct: 61 IIKLIENSKHIIVIIGAGASIG---PDFRSPGGLYDSIAKEG 99
>UniRef50_Q6CAJ8 Cluster: Similar to sp|P53687 Saccharomyces
cerevisiae HST3 protein; n=1; Yarrowia lipolytica|Rep:
Similar to sp|P53687 Saccharomyces cerevisiae HST3
protein - Yarrowia lipolytica (Candida lipolytica)
Length = 385
Score = 38.3 bits (85), Expect = 0.14
Identities = 18/29 (62%), Positives = 21/29 (72%)
Frame = +1
Query: 340 LAQLVKDSKHIVVHTGAGISTSAGIPDFR 426
L Q++ K +V TGAGIS SAGIPDFR
Sbjct: 17 LQQILGKCKRVVCVTGAGISCSAGIPDFR 45
>UniRef50_A4QX96 Cluster: Putative uncharacterized protein; n=2;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 534
Score = 38.3 bits (85), Expect = 0.14
Identities = 16/21 (76%), Positives = 18/21 (85%)
Frame = +1
Query: 370 IVVHTGAGISTSAGIPDFRGP 432
I++ GAGISTSAGIPDFR P
Sbjct: 38 IIILAGAGISTSAGIPDFRSP 58
>UniRef50_A3LN35 Cluster: NAD-dependent histone deacetylase SIR2;
n=1; Pichia stipitis|Rep: NAD-dependent histone
deacetylase SIR2 - Pichia stipitis (Yeast)
Length = 391
Score = 38.3 bits (85), Expect = 0.14
Identities = 20/36 (55%), Positives = 26/36 (72%)
Frame = +1
Query: 337 LLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 444
LL+ L +K I+V +GAGISTS GIPDFR G++
Sbjct: 103 LLSDLTS-AKKIMVISGAGISTSLGIPDFRSFKGLY 137
>UniRef50_A2QWZ2 Cluster: Function: human SIRT5 belongs to the
Sir2-like proteins precursor; n=1; Aspergillus
niger|Rep: Function: human SIRT5 belongs to the
Sir2-like proteins precursor - Aspergillus niger
Length = 258
Score = 38.3 bits (85), Expect = 0.14
Identities = 14/31 (45%), Positives = 21/31 (67%)
Frame = +1
Query: 352 VKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 444
+K + ++ GAGIS S+G+P FRG G+W
Sbjct: 18 LKGCRRVIALLGAGISASSGLPTFRGAGGLW 48
>UniRef50_Q55PY8 Cluster: Putative uncharacterized protein; n=2;
Filobasidiella neoformans|Rep: Putative uncharacterized
protein - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 361
Score = 29.1 bits (62), Expect(2) = 0.15
Identities = 13/33 (39%), Positives = 20/33 (60%)
Frame = +1
Query: 349 LVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWT 447
L K + V+ TGAG+S +GI +RG G ++
Sbjct: 36 LEKGNGKTVILTGAGVSVDSGIRAYRGKEGSYS 68
Score = 28.3 bits (60), Expect(2) = 0.15
Identities = 12/35 (34%), Positives = 17/35 (48%)
Frame = +1
Query: 493 DAQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKS 597
DAQP TH+ ++QN+D LH K+
Sbjct: 107 DAQPNPTHIYIAALLHLGLAPNLITQNVDNLHPKA 141
>UniRef50_Q4QKL5 Cluster: NAD-dependent deacetylase sirtuin 5; n=11;
Haemophilus influenzae|Rep: NAD-dependent deacetylase
sirtuin 5 - Haemophilus influenzae (strain 86-028NP)
Length = 281
Score = 37.9 bits (84), Expect = 0.19
Identities = 17/50 (34%), Positives = 29/50 (58%)
Frame = +1
Query: 346 QLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKPTINVSFAD 495
+L++ + I++ GAG+S +G+PDFR G W K+ N+SF +
Sbjct: 10 ELIRKADGILITAGAGMSVDSGLPDFRSVGGFWNAYPMFKEH--NISFEE 57
>UniRef50_Q1D737 Cluster: NAD-dependent deacetylase; n=1; Myxococcus
xanthus DK 1622|Rep: NAD-dependent deacetylase -
Myxococcus xanthus (strain DK 1622)
Length = 245
Score = 37.9 bits (84), Expect = 0.19
Identities = 16/33 (48%), Positives = 24/33 (72%), Gaps = 1/33 (3%)
Frame = +1
Query: 349 LVKDSKH-IVVHTGAGISTSAGIPDFRGPNGVW 444
L+ DS ++V TGAG+S +G+P FRG +G+W
Sbjct: 4 LILDSNTWLLVLTGAGVSAESGVPTFRGMSGLW 36
>UniRef50_A3WK56 Cluster: SIR2-like regulatory protein,
NAD-dependent protein deacetylase; n=1; Idiomarina
baltica OS145|Rep: SIR2-like regulatory protein,
NAD-dependent protein deacetylase - Idiomarina baltica
OS145
Length = 279
Score = 37.9 bits (84), Expect = 0.19
Identities = 26/106 (24%), Positives = 45/106 (42%), Gaps = 17/106 (16%)
Frame = +1
Query: 334 VLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWT----------LEKEGKKPTI-- 477
V A+L++ + + +GAG+ST +GIP +R G W + + +
Sbjct: 9 VKAAELLRGNTPFTLLSGAGLSTDSGIPAYRNAQGQWVHSPPMQHHDFMNNDAARKRYWA 68
Query: 478 -----NVSFADAQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSG 600
++ AQP + H ++QN+DGLH K+G
Sbjct: 69 RSLGGWLNLYHAQPNRAHQVIAQFQQHGFIDTVITQNVDGLHQKAG 114
>UniRef50_A7SK95 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 323
Score = 37.9 bits (84), Expect = 0.19
Identities = 33/124 (26%), Positives = 50/124 (40%), Gaps = 20/124 (16%)
Frame = +1
Query: 289 VPEKFDSNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGP-NGVWTLEKEG- 462
VPE S +L+ L + + ++ I V TGAGIST +GI D+R G++ + +
Sbjct: 36 VPEFHTSKQELSYITSRLDEFIAENPKIFVITGAGISTESGIRDYRSEGKGLYAITNDRP 95
Query: 463 -------KKPTIN-----------VSFADAQPTKTHMXXXXXXXXXXXXXXVSQNIDGLH 588
K + F QP + H V+QN+D LH
Sbjct: 96 MEYQVFLKSAVMRQRYWARNYVGWPEFGSRQPNEAHYALAKLETLGSVHSLVTQNVDALH 155
Query: 589 LKSG 600
K+G
Sbjct: 156 TKAG 159
>UniRef50_A6XDL2 Cluster: Sirtuin 1; n=2; Schistosoma|Rep: Sirtuin 1
- Schistosoma mansoni (Blood fluke)
Length = 568
Score = 37.9 bits (84), Expect = 0.19
Identities = 17/32 (53%), Positives = 22/32 (68%)
Frame = +1
Query: 349 LVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 444
L+ I+V TGAGIS S GIPDFR +G++
Sbjct: 150 LLSTCTSILVITGAGISVSCGIPDFRSRDGIY 181
>UniRef50_Q8IXJ6 Cluster: NAD-dependent deacetylase sirtuin-2; n=31;
Coelomata|Rep: NAD-dependent deacetylase sirtuin-2 -
Homo sapiens (Human)
Length = 389
Score = 37.9 bits (84), Expect = 0.19
Identities = 19/33 (57%), Positives = 25/33 (75%), Gaps = 2/33 (6%)
Frame = +1
Query: 364 KHIVVHTGAGISTSAGIPDFRGPN-GVW-TLEK 456
+ ++ GAGISTSAGIPDFR P+ G++ LEK
Sbjct: 77 RRVICLVGAGISTSAGIPDFRSPSTGLYDNLEK 109
>UniRef50_Q6C8C7 Cluster: Similar to DEHA0C01507g Debaryomyces
hansenii IPF 2468.1; n=2; Ascomycota|Rep: Similar to
DEHA0C01507g Debaryomyces hansenii IPF 2468.1 - Yarrowia
lipolytica (Candida lipolytica)
Length = 303
Score = 37.5 bits (83), Expect = 0.25
Identities = 14/28 (50%), Positives = 20/28 (71%)
Frame = +1
Query: 361 SKHIVVHTGAGISTSAGIPDFRGPNGVW 444
S+ I+ GAG+S S+G+P FRG G+W
Sbjct: 16 SRKILALVGAGLSQSSGLPTFRGEGGIW 43
>UniRef50_A6SP88 Cluster: Putative uncharacterized protein; n=2;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 332
Score = 37.5 bits (83), Expect = 0.25
Identities = 20/51 (39%), Positives = 28/51 (54%)
Frame = +1
Query: 292 PEKFDSNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 444
PE SND + K VL + S ++ GAG+ S+G+ FRGP G+W
Sbjct: 17 PEHRPSNDVASFKKVLAS-----STRVLALCGAGLGASSGLDTFRGPGGMW 62
>UniRef50_Q9NTG7 Cluster: NAD-dependent deacetylase sirtuin-3,
mitochondrial precursor; n=22; Euteleostomi|Rep:
NAD-dependent deacetylase sirtuin-3, mitochondrial
precursor - Homo sapiens (Human)
Length = 399
Score = 37.5 bits (83), Expect = 0.25
Identities = 20/44 (45%), Positives = 28/44 (63%), Gaps = 2/44 (4%)
Frame = +1
Query: 307 SNDKLNQKCVLLAQLVKDS--KHIVVHTGAGISTSAGIPDFRGP 432
S+DK +A+L++ + +VV GAGIST +GIPDFR P
Sbjct: 117 SSDKGKLSLQDVAELIRARACQRVVVMVGAGISTPSGIPDFRSP 160
>UniRef50_UPI0000499DEA Cluster: Sir2 family transcriptional
regulator; n=1; Entamoeba histolytica HM-1:IMSS|Rep:
Sir2 family transcriptional regulator - Entamoeba
histolytica HM-1:IMSS
Length = 383
Score = 37.1 bits (82), Expect = 0.33
Identities = 15/23 (65%), Positives = 19/23 (82%)
Frame = +1
Query: 364 KHIVVHTGAGISTSAGIPDFRGP 432
K+I+ GAG+ST+AGIPDFR P
Sbjct: 135 KNIIALVGAGMSTTAGIPDFRSP 157
>UniRef50_A2ABY8 Cluster: Sirtuin 7 (Silent mating type information
regulation 2, homolog) 7; n=2; Murinae|Rep: Sirtuin 7
(Silent mating type information regulation 2, homolog) 7
- Mus musculus (Mouse)
Length = 121
Score = 37.1 bits (82), Expect = 0.33
Identities = 19/43 (44%), Positives = 27/43 (62%)
Frame = +1
Query: 295 EKFDSNDKLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDF 423
E D ++L +K LA V+ ++H+VV+TGAGIST I F
Sbjct: 78 EVCDDPEELRRKVRELAGAVRSARHLVVYTGAGISTCRQIDRF 120
>UniRef50_A4A8B4 Cluster: Silent information regulator protein Sir2;
n=1; Congregibacter litoralis KT71|Rep: Silent
information regulator protein Sir2 - Congregibacter
litoralis KT71
Length = 297
Score = 37.1 bits (82), Expect = 0.33
Identities = 31/111 (27%), Positives = 45/111 (40%), Gaps = 17/111 (15%)
Frame = +1
Query: 319 LNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKE------------- 459
L+ + L+ L+ D ++V TGAGIS S GIP +R G W
Sbjct: 7 LHAESDFLSALI-DHAPVLVITGAGISVSTGIPTYRDEKGAWLRSNPITHQEFVADRRQR 65
Query: 460 ----GKKPTINVSFADAQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSG 600
G+ + DA+P K H V+QN+D LH ++G
Sbjct: 66 QRYWGRSLLGWPAVRDAKPAKGHRLLAQLEHHGLVSHIVTQNVDRLHQRAG 116
>UniRef50_Q1RL71 Cluster: Zinc finger protein; n=2; Ciona
intestinalis|Rep: Zinc finger protein - Ciona
intestinalis (Transparent sea squirt)
Length = 523
Score = 37.1 bits (82), Expect = 0.33
Identities = 17/33 (51%), Positives = 24/33 (72%), Gaps = 2/33 (6%)
Frame = +1
Query: 340 LAQLVKDS--KHIVVHTGAGISTSAGIPDFRGP 432
+A+L+ ++I+V GAGIST +GIPDFR P
Sbjct: 110 VAELISSGGVRNIIVMAGAGISTGSGIPDFRTP 142
>UniRef50_A2F9H1 Cluster: Transcriptional regulator, Sir2 family
protein; n=2; Trichomonas vaginalis|Rep: Transcriptional
regulator, Sir2 family protein - Trichomonas vaginalis
G3
Length = 304
Score = 37.1 bits (82), Expect = 0.33
Identities = 33/104 (31%), Positives = 48/104 (46%), Gaps = 22/104 (21%)
Frame = +1
Query: 361 SKHIVVHTGAGISTSAGIPDFRG----------------PNGVWTLE--KEGKKPTINVS 486
+K I+ TGAGIST+AGIPDFR P+ V+ ++ KE ++P ++
Sbjct: 24 AKKIIFLTGAGISTAAGIPDFRSIGTGFYSNLQKYNLPEPSDVFNIKYFKENQEPFYDLC 83
Query: 487 FA----DAQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSGVP 606
+ +PT H +QNIDGL +GVP
Sbjct: 84 PSLLPGKYKPTFIHYFGAYMAKKGILLKQYTQNIDGLERIAGVP 127
>UniRef50_Q882K4 Cluster: NAD-dependent deacetylase 3; n=5;
Pseudomonas|Rep: NAD-dependent deacetylase 3 -
Pseudomonas syringae pv. tomato
Length = 281
Score = 37.1 bits (82), Expect = 0.33
Identities = 16/26 (61%), Positives = 21/26 (80%)
Frame = +1
Query: 364 KHIVVHTGAGISTSAGIPDFRGPNGV 441
K +V TGAGIST++GIPD+R +GV
Sbjct: 20 KSFLVVTGAGISTASGIPDYRDKDGV 45
>UniRef50_Q1D9X2 Cluster: Sir2 family protein; n=1; Myxococcus
xanthus DK 1622|Rep: Sir2 family protein - Myxococcus
xanthus (strain DK 1622)
Length = 287
Score = 36.7 bits (81), Expect = 0.44
Identities = 30/97 (30%), Positives = 41/97 (42%), Gaps = 18/97 (18%)
Frame = +1
Query: 373 VVHTGAGISTSAGIPDFRGP-------NGVWTLEKEGKKPTINV-----------SFADA 498
VV TGAG ST +GIPD+RGP N + E +P + F+ A
Sbjct: 30 VVLTGAGCSTESGIPDYRGPGTRARARNPIQHREFL-TRPEVRARYWARSLMGWPRFSSA 88
Query: 499 QPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSGVPR 609
+P H ++QN+DGLH +G R
Sbjct: 89 RPNAAHAALAELEQAGHVRGLITQNVDGLHHAAGSSR 125
>UniRef50_A1ZZG3 Cluster: NAD-dependent deacetylase; n=35;
Bacteria|Rep: NAD-dependent deacetylase - Microscilla
marina ATCC 23134
Length = 245
Score = 36.7 bits (81), Expect = 0.44
Identities = 33/111 (29%), Positives = 50/111 (45%), Gaps = 17/111 (15%)
Frame = +1
Query: 319 LNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW-------TLEKEG--KKP 471
L+ K +++ + + IVV TGAGIS +GI FR +G+W EG K
Sbjct: 2 LSFKSQQVSKSIMSKQKIVVLTGAGISAESGISTFRDSDGLWENHDVMEVASPEGWQKDR 61
Query: 472 TINVSFAD--------AQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSG 600
+ + F + AQP + H+ ++QNID LH K+G
Sbjct: 62 ALVLEFYNQRRTHALAAQPNEGHL-ALARLEAKYEVVIITQNIDDLHEKAG 111
>UniRef50_Q89EA6 Cluster: NAD-dependent deacetylase 2; n=9;
Proteobacteria|Rep: NAD-dependent deacetylase 2 -
Bradyrhizobium japonicum
Length = 273
Score = 36.7 bits (81), Expect = 0.44
Identities = 16/35 (45%), Positives = 22/35 (62%)
Frame = +1
Query: 340 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 444
L V + + V TGAG ST++GIPD+R +G W
Sbjct: 11 LQDFVARHQRLFVLTGAGCSTNSGIPDYRDSHGNW 45
>UniRef50_Q9RL35 Cluster: NAD-dependent deacetylase 1; n=8;
Actinomycetales|Rep: NAD-dependent deacetylase 1 -
Streptomyces coelicolor
Length = 299
Score = 36.7 bits (81), Expect = 0.44
Identities = 28/94 (29%), Positives = 41/94 (43%), Gaps = 17/94 (18%)
Frame = +1
Query: 370 IVVHTGAGISTSAGIPDFRGPNGV-----------WTLEKEGKKPTINVS------FADA 498
++V +GAGIST +GIPD+RG G +T E ++ S F A
Sbjct: 34 VLVLSGAGISTESGIPDYRGEGGSLSRHTPMTYQDFTAHPEARRRYWARSHLGWRTFGRA 93
Query: 499 QPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSG 600
+P H ++QN+DGLH +G
Sbjct: 94 RPNAGHRSVAAFGRHGLLTGVITQNVDGLHQAAG 127
>UniRef50_Q07FY7 Cluster: Sirtuin (Silent mating type information
regulation 2 homolog) 3; n=3; Xenopus|Rep: Sirtuin
(Silent mating type information regulation 2 homolog) 3
- Xenopus tropicalis (Western clawed frog) (Silurana
tropicalis)
Length = 401
Score = 36.3 bits (80), Expect = 0.58
Identities = 15/22 (68%), Positives = 19/22 (86%)
Frame = +1
Query: 367 HIVVHTGAGISTSAGIPDFRGP 432
+I+V GAGIST++GIPDFR P
Sbjct: 128 NIIVMAGAGISTASGIPDFRTP 149
>UniRef50_Q62HT8 Cluster: Transcriptional regulator, Sir2 family;
n=39; Bacteria|Rep: Transcriptional regulator, Sir2
family - Burkholderia mallei (Pseudomonas mallei)
Length = 450
Score = 36.3 bits (80), Expect = 0.58
Identities = 13/25 (52%), Positives = 18/25 (72%)
Frame = +1
Query: 370 IVVHTGAGISTSAGIPDFRGPNGVW 444
++V GAGI +G+PDFRG G+W
Sbjct: 196 LLVTAGAGIGIDSGLPDFRGAEGLW 220
>UniRef50_A0C6J0 Cluster: Chromosome undetermined scaffold_152,
whole genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_152,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 449
Score = 36.3 bits (80), Expect = 0.58
Identities = 33/106 (31%), Positives = 42/106 (39%), Gaps = 23/106 (21%)
Frame = +1
Query: 355 KDSKHIVVHTGAGISTSAGIPDFR----------------GPNGVWTLEKEGKKPTINVS 486
K + + V GAG+S +AGIPDFR P V+ +E K P
Sbjct: 207 KKFQRVCVLAGAGMSVAAGIPDFRTPGTGLYSQIQKYNLPSPESVFEIEYFKKNPEAFYC 266
Query: 487 FA-------DAQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSGV 603
A DA+PT H +QNIDGL L +GV
Sbjct: 267 VAKEFLLSFDAKPTLAHKFLKFLDSRGQLLKCFTQNIDGLELDAGV 312
>UniRef50_Q6FKU1 Cluster: Similar to sp|P53686 Saccharomyces
cerevisiae YPL015c; n=3; Saccharomycetales|Rep: Similar
to sp|P53686 Saccharomyces cerevisiae YPL015c - Candida
glabrata (Yeast) (Torulopsis glabrata)
Length = 364
Score = 36.3 bits (80), Expect = 0.58
Identities = 15/24 (62%), Positives = 18/24 (75%)
Frame = +1
Query: 361 SKHIVVHTGAGISTSAGIPDFRGP 432
S ++ GAGISTS+GIPDFR P
Sbjct: 16 SSKVIFLVGAGISTSSGIPDFRSP 39
>UniRef50_Q9I4E1 Cluster: NAD-dependent deacetylase 2; n=6;
Pseudomonadaceae|Rep: NAD-dependent deacetylase 2 -
Pseudomonas aeruginosa
Length = 256
Score = 36.3 bits (80), Expect = 0.58
Identities = 16/44 (36%), Positives = 28/44 (63%)
Frame = +1
Query: 340 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVWTLEKEGKKP 471
+AQ ++ ++ I+V TGAG+S +G+P +RG G++ E P
Sbjct: 10 VAQALRRAERILVITGAGLSADSGMPTYRGLGGLYNGRTEEGLP 53
>UniRef50_Q25337 Cluster: NAD-dependent deacetylase SIR2 homolog;
n=6; Leishmania|Rep: NAD-dependent deacetylase SIR2
homolog - Leishmania major
Length = 381
Score = 35.9 bits (79), Expect = 0.77
Identities = 35/112 (31%), Positives = 44/112 (39%), Gaps = 24/112 (21%)
Frame = +1
Query: 355 KDSKHIVVHTGAGISTSAGIPDFRG----------------PNGVWTLEKEGKKPTINVS 486
KD + I+V GAG S +AGIPDFR P ++L +KP I S
Sbjct: 29 KDVRRILVLVGAGASVAAGIPDFRSSDTGIYAKLGKYNLDDPTDAFSLTLLREKPEIFYS 88
Query: 487 FA--------DAQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSGVPRKFL 618
A QPT H +QNIDGL +GV + L
Sbjct: 89 IARELNLWPGHFQPTAVHHFIRLLQDEGRLLRCCTQNIDGLEKAAGVSPELL 140
>UniRef50_Q6MJJ2 Cluster: NAD-dependent deacetylase; n=5;
Proteobacteria|Rep: NAD-dependent deacetylase -
Bdellovibrio bacteriovorus
Length = 235
Score = 35.9 bits (79), Expect = 0.77
Identities = 15/27 (55%), Positives = 20/27 (74%)
Frame = +1
Query: 364 KHIVVHTGAGISTSAGIPDFRGPNGVW 444
K+IV+ TGAGIS +GI FR +G+W
Sbjct: 7 KNIVILTGAGISAESGIRTFRDQDGLW 33
>UniRef50_UPI00005A356B Cluster: PREDICTED: similar to NAD-dependent
deacetylase sirtuin-3, mitochondrial precursor
(SIR2-like protein 3) (hSIRT3) isoform 1; n=2; Canis
lupus familiaris|Rep: PREDICTED: similar to
NAD-dependent deacetylase sirtuin-3, mitochondrial
precursor (SIR2-like protein 3) (hSIRT3) isoform 1 -
Canis familiaris
Length = 248
Score = 35.5 bits (78), Expect = 1.0
Identities = 16/33 (48%), Positives = 24/33 (72%), Gaps = 2/33 (6%)
Frame = +1
Query: 340 LAQLVKDS--KHIVVHTGAGISTSAGIPDFRGP 432
+A+L++ + ++V GAGIST +GIPDFR P
Sbjct: 101 IAELIRARACQRVLVMVGAGISTPSGIPDFRSP 133
>UniRef50_A0JXS0 Cluster: Silent information regulator protein Sir2
precursor; n=11; Actinomycetales|Rep: Silent information
regulator protein Sir2 precursor - Arthrobacter sp.
(strain FB24)
Length = 306
Score = 35.5 bits (78), Expect = 1.0
Identities = 13/18 (72%), Positives = 17/18 (94%)
Frame = +1
Query: 382 TGAGISTSAGIPDFRGPN 435
TGAG+ST +GIPD+RGP+
Sbjct: 48 TGAGLSTDSGIPDYRGPD 65
>UniRef50_Q4DP02 Cluster: Silent information regulator 2, putative;
n=4; Trypanosoma|Rep: Silent information regulator 2,
putative - Trypanosoma cruzi
Length = 359
Score = 35.5 bits (78), Expect = 1.0
Identities = 15/22 (68%), Positives = 18/22 (81%)
Frame = +1
Query: 370 IVVHTGAGISTSAGIPDFRGPN 435
I+V GAGIS +AGIPDFR P+
Sbjct: 32 ILVMAGAGISVAAGIPDFRSPH 53
>UniRef50_A2F8N6 Cluster: Transcriptional regulator, Sir2 family
protein; n=1; Trichomonas vaginalis G3|Rep:
Transcriptional regulator, Sir2 family protein -
Trichomonas vaginalis G3
Length = 320
Score = 35.5 bits (78), Expect = 1.0
Identities = 16/39 (41%), Positives = 27/39 (69%), Gaps = 1/39 (2%)
Frame = +1
Query: 358 DSKHIVVHTGAGISTSAGIPDFRGPN-GVWTLEKEGKKP 471
++K I++ +GAG S ++GIPDFR P G+++ K+ P
Sbjct: 35 NAKKILIFSGAGTSVASGIPDFRSPKIGLYSQLKKYNLP 73
>UniRef50_Q9I4L0 Cluster: NAD-dependent deacetylase 1; n=10;
Bacteria|Rep: NAD-dependent deacetylase 1 - Pseudomonas
aeruginosa
Length = 250
Score = 35.5 bits (78), Expect = 1.0
Identities = 28/106 (26%), Positives = 43/106 (40%), Gaps = 19/106 (17%)
Frame = +1
Query: 340 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGP-NGVWTLEKEGKKPTINVSFAD------- 495
+ +L+ ++ +V+ TGAG+S +GIP FR G+W T +FAD
Sbjct: 4 VVELLAGARRLVIFTGAGVSAESGIPTFRDALGGLWARYDPAALAT-PAAFADDPALVWG 62
Query: 496 -----------AQPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSG 600
QP H V+QN+D LH ++G
Sbjct: 63 WYEWRRLKVLGVQPNPAHRAIAALSGRIANTRLVTQNVDDLHERAG 108
>UniRef50_Q2U9Y7 Cluster: Sirtuin 4 and related class II sirtuins;
n=10; Pezizomycotina|Rep: Sirtuin 4 and related class II
sirtuins - Aspergillus oryzae
Length = 407
Score = 35.1 bits (77), Expect = 1.4
Identities = 14/28 (50%), Positives = 20/28 (71%)
Frame = +1
Query: 373 VVHTGAGISTSAGIPDFRGPNGVWTLEK 456
V+ TGAGIS ++G+ D+RG NG + K
Sbjct: 85 VLLTGAGISVASGLSDYRGENGTYVTNK 112
>UniRef50_Q8F3Z6 Cluster: NAD-dependent deacetylase; n=4;
Leptospira|Rep: NAD-dependent deacetylase - Leptospira
interrogans
Length = 246
Score = 35.1 bits (77), Expect = 1.4
Identities = 26/91 (28%), Positives = 38/91 (41%), Gaps = 18/91 (19%)
Frame = +1
Query: 382 TGAGISTSAGIPDFRGPNGVW---------TLEKEGKKPTI---------NVSFADAQPT 507
+GAGIS +GIP FRG G+W T + K P + N+ +P
Sbjct: 19 SGAGISAESGIPTFRGSEGLWKNFRAEDLATPQAFSKNPKLVWEWYLWRRNI-IETKRPN 77
Query: 508 KTHMXXXXXXXXXXXXXXVSQNIDGLHLKSG 600
H ++QN+DGLH ++G
Sbjct: 78 PGHFALVELERIHPDFFLITQNVDGLHSQAG 108
>UniRef50_Q8A3H9 Cluster: NAD-dependent deacetylase; n=3;
Bacteroides|Rep: NAD-dependent deacetylase - Bacteroides
thetaiotaomicron
Length = 234
Score = 35.1 bits (77), Expect = 1.4
Identities = 27/96 (28%), Positives = 44/96 (45%), Gaps = 17/96 (17%)
Frame = +1
Query: 364 KHIVVHTGAGISTSAGIPDFRGPNGVW---------TLEKEGKKPTINVSFADA------ 498
K++VV TGAG+S +GI FR G+W T E + P + ++F +A
Sbjct: 2 KNLVVLTGAGMSAESGISTFRDAGGLWDKYPVEQVATPEGYQRDPALVINFYNARRKQLL 61
Query: 499 --QPTKTHMXXXXXXXXXXXXXXVSQNIDGLHLKSG 600
+P + H ++QN+D LH ++G
Sbjct: 62 EVKPNRGH-ELLAELEKNFNVTVITQNVDNLHERAG 96
>UniRef50_P53686 Cluster: NAD-dependent deacetylase HST2; n=4;
Saccharomyces cerevisiae|Rep: NAD-dependent deacetylase
HST2 - Saccharomyces cerevisiae (Baker's yeast)
Length = 357
Score = 35.1 bits (77), Expect = 1.4
Identities = 14/21 (66%), Positives = 16/21 (76%)
Frame = +1
Query: 370 IVVHTGAGISTSAGIPDFRGP 432
++ GAGISTS GIPDFR P
Sbjct: 27 VIFMVGAGISTSCGIPDFRSP 47
>UniRef50_Q5P3W1 Cluster: NAD-dependent deacetylase 2; n=4;
Proteobacteria|Rep: NAD-dependent deacetylase 2 -
Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum
(strain EbN1))
Length = 260
Score = 34.7 bits (76), Expect = 1.8
Identities = 14/35 (40%), Positives = 24/35 (68%)
Frame = +1
Query: 340 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 444
+A+L+ + I+ TGAGIS +G+P +RG G++
Sbjct: 10 VARLIAGAPRILFITGAGISADSGLPTYRGIGGLY 44
>UniRef50_A2DKY5 Cluster: Transcriptional regulator, Sir2 family
protein; n=1; Trichomonas vaginalis G3|Rep:
Transcriptional regulator, Sir2 family protein -
Trichomonas vaginalis G3
Length = 180
Score = 34.7 bits (76), Expect = 1.8
Identities = 17/36 (47%), Positives = 24/36 (66%), Gaps = 2/36 (5%)
Frame = +1
Query: 319 LNQKCVLLAQLVKDS--KHIVVHTGAGISTSAGIPD 420
+NQ +LA L+K K++VV TG+GI + GIPD
Sbjct: 1 MNQNISVLANLLKSGNYKNVVVMTGSGICNACGIPD 36
>UniRef50_A5DW75 Cluster: Putative uncharacterized protein; n=1;
Lodderomyces elongisporus NRRL YB-4239|Rep: Putative
uncharacterized protein - Lodderomyces elongisporus
(Yeast) (Saccharomyces elongisporus)
Length = 379
Score = 34.7 bits (76), Expect = 1.8
Identities = 14/27 (51%), Positives = 18/27 (66%)
Frame = +1
Query: 364 KHIVVHTGAGISTSAGIPDFRGPNGVW 444
K IV GAG+ S+G+P FRG G+W
Sbjct: 16 KKIVALVGAGLLASSGLPVFRGSQGLW 42
>UniRef50_A2QUR5 Cluster: Remark: the H. sapiens SIRT4 belongs to a
group of four human SIRT proteins; n=1; Aspergillus
niger|Rep: Remark: the H. sapiens SIRT4 belongs to a
group of four human SIRT proteins - Aspergillus niger
Length = 357
Score = 34.7 bits (76), Expect = 1.8
Identities = 14/28 (50%), Positives = 20/28 (71%)
Frame = +1
Query: 373 VVHTGAGISTSAGIPDFRGPNGVWTLEK 456
V+ TGAGIS ++G+ D+RG NG + K
Sbjct: 58 VLLTGAGISVASGLSDYRGENGTYITNK 85
>UniRef50_Q4APN6 Cluster: Silent information regulator protein Sir2;
n=1; Chlorobium phaeobacteroides BS1|Rep: Silent
information regulator protein Sir2 - Chlorobium
phaeobacteroides BS1
Length = 217
Score = 34.3 bits (75), Expect = 2.4
Identities = 11/21 (52%), Positives = 16/21 (76%)
Frame = +1
Query: 382 TGAGISTSAGIPDFRGPNGVW 444
TGAG+S +G+P +RG G+W
Sbjct: 4 TGAGMSAESGVPTYRGKGGIW 24
>UniRef50_A6Q946 Cluster: Transcriptional regulator, Sir2 family;
n=1; Sulfurovum sp. NBC37-1|Rep: Transcriptional
regulator, Sir2 family - Sulfurovum sp. (strain NBC37-1)
Length = 271
Score = 34.3 bits (75), Expect = 2.4
Identities = 11/33 (33%), Positives = 21/33 (63%)
Frame = +1
Query: 346 QLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 444
+++ ++ + + GAG+ +G+PDFRG G W
Sbjct: 11 KVLNETDALFIMAGAGMGVDSGLPDFRGVEGFW 43
>UniRef50_A5B6H9 Cluster: Putative uncharacterized protein; n=3;
Vitis vinifera|Rep: Putative uncharacterized protein -
Vitis vinifera (Grape)
Length = 1326
Score = 34.3 bits (75), Expect = 2.4
Identities = 17/57 (29%), Positives = 28/57 (49%)
Frame = -3
Query: 560 MYLSFFISTNFFKIIWVFVGCASANDTLMVGFLPSFSKVHTPFGPLKSGIPAEVLMP 390
++++FF FF+ I V + S T + L + VH P PL+ +P +L P
Sbjct: 8 LFITFFFFXFFFQSICVLLDITSTKCTKITSTLTTTIIVHPPSPPLREALPLXILGP 64
>UniRef50_Q54LF0 Cluster: Ankyrin repeat-containing protein; n=1;
Dictyostelium discoideum AX4|Rep: Ankyrin
repeat-containing protein - Dictyostelium discoideum AX4
Length = 778
Score = 34.3 bits (75), Expect = 2.4
Identities = 14/32 (43%), Positives = 23/32 (71%)
Frame = +1
Query: 364 KHIVVHTGAGISTSAGIPDFRGPNGVWTLEKE 459
K+++V +GAGIS +AGIP +R +G+ K+
Sbjct: 489 KNVIVLSGAGISANAGIPPYRTKDGLLAKNKQ 520
>UniRef50_Q7S223 Cluster: Putative uncharacterized protein
NCU05973.1; n=1; Neurospora crassa|Rep: Putative
uncharacterized protein NCU05973.1 - Neurospora crassa
Length = 334
Score = 34.3 bits (75), Expect = 2.4
Identities = 14/43 (32%), Positives = 25/43 (58%)
Frame = +1
Query: 316 KLNQKCVLLAQLVKDSKHIVVHTGAGISTSAGIPDFRGPNGVW 444
++N +L K + + + GAG+S ++G+P FRG G+W
Sbjct: 4 RINNLAAFHQKLAKADRILAI-CGAGLSAASGLPTFRGVGGLW 45
>UniRef50_A6FYM4 Cluster: Sir2 family protein; n=1; Plesiocystis
pacifica SIR-1|Rep: Sir2 family protein - Plesiocystis
pacifica SIR-1
Length = 297
Score = 33.9 bits (74), Expect = 3.1
Identities = 16/30 (53%), Positives = 21/30 (70%)
Frame = +1
Query: 340 LAQLVKDSKHIVVHTGAGISTSAGIPDFRG 429
LA+L + +V TGAG ST +GIPD+RG
Sbjct: 27 LAELCA-GRRVVALTGAGCSTESGIPDYRG 55
>UniRef50_A5K7T7 Cluster: NAD-dependent deacetylase, putative; n=5;
Plasmodium|Rep: NAD-dependent deacetylase, putative -
Plasmodium vivax
Length = 306
Score = 33.9 bits (74), Expect = 3.1
Identities = 14/37 (37%), Positives = 23/37 (62%), Gaps = 1/37 (2%)
Frame = +1
Query: 340 LAQLVKDSKHIVVHTGAGISTSAGIPDFRGPN-GVWT 447
LA +++ ++V TG+G S + IP FRG N +W+
Sbjct: 21 LACMIRGCTYVVALTGSGTSAESNIPSFRGANSSIWS 57
>UniRef50_Q2KH01 Cluster: Putative uncharacterized protein; n=2;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea 70-15
Length = 449
Score = 33.9 bits (74), Expect = 3.1
Identities = 15/26 (57%), Positives = 19/26 (73%)
Frame = +1
Query: 346 QLVKDSKHIVVHTGAGISTSAGIPDF 423
QL++ + VV +GAGIS SAGIP F
Sbjct: 94 QLLRSHRQTVVFSGAGISVSAGIPTF 119
>UniRef50_Q8ZFR1 Cluster: NAD-dependent deacetylase; n=149; cellular
organisms|Rep: NAD-dependent deacetylase - Yersinia
pestis
Length = 278
Score = 33.9 bits (74), Expect = 3.1
Identities = 14/25 (56%), Positives = 18/25 (72%)
Frame = +1
Query: 370 IVVHTGAGISTSAGIPDFRGPNGVW 444
+VV TGAGIS +GI FR +G+W
Sbjct: 41 VVVLTGAGISAESGIRTFRADDGLW 65
>UniRef50_O25849 Cluster: NAD-dependent deacetylase; n=11;
Bacteria|Rep: NAD-dependent deacetylase - Helicobacter
pylori (Campylobacter pylori)
Length = 229
Score = 33.9 bits (74), Expect = 3.1
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +1
Query: 364 KHIVVHTGAGISTSAGIPDFRGPNGVW 444
K++V+ +GAGIS +GI FR +G+W
Sbjct: 2 KNLVILSGAGISAESGIKTFRDADGLW 28
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 615,077,831
Number of Sequences: 1657284
Number of extensions: 12621420
Number of successful extensions: 27980
Number of sequences better than 10.0: 275
Number of HSP's better than 10.0 without gapping: 27028
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 27966
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 44807090004
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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