Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmte5c07
(761 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC022515-1|AAH22515.1| 367|Homo sapiens testis-specific serine ... 190 4e-48
AY028964-1|AAK27734.1| 367|Homo sapiens testis-specific serine/... 190 4e-48
AB284522-1|BAF41973.1| 367|Homo sapiens testis-specific serine ... 190 4e-48
CR456587-1|CAG30473.1| 358|Homo sapiens STK22A protein. 181 3e-45
BC037781-1|AAH37781.1| 358|Homo sapiens testis-specific serine ... 181 3e-45
AF362953-1|AAK98531.1| 358|Homo sapiens testis specific serine/... 181 3e-45
AB284523-1|BAF41974.1| 358|Homo sapiens testis-specific serine ... 181 3e-45
AY461663-1|AAS17971.1| 328|Homo sapiens testis-specific serine ... 176 8e-44
BC035354-1|AAH35354.1| 268|Homo sapiens testis-specific serine ... 172 1e-42
AY048701-1|AAL02128.1| 268|Homo sapiens TSSK3 protein. 172 1e-42
AL109945-4|CAI22888.1| 268|Homo sapiens testis-specific serine ... 172 1e-42
AF296450-1|AAK97141.1| 268|Homo sapiens testis-specific serine/... 172 1e-42
AK131042-1|BAC85482.1| 338|Homo sapiens protein ( Homo sapiens ... 166 9e-41
BC014611-1|AAH14611.1| 273|Homo sapiens testis-specific serine ... 153 7e-37
AK172841-1|BAD18805.1| 406|Homo sapiens protein ( Homo sapiens ... 153 7e-37
AF329483-1|AAK48827.1| 273|Homo sapiens serine/threonine protei... 153 7e-37
BC117183-1|AAI17184.1| 926|Homo sapiens SNF1-like kinase 2 prot... 151 3e-36
BC113459-1|AAI13460.1| 926|Homo sapiens SNF1-like kinase 2 prot... 151 3e-36
AB084424-1|BAB91442.1| 346|Homo sapiens KIAA0781 protein protein. 151 3e-36
AB018324-1|BAA34501.3| 950|Homo sapiens KIAA0781 protein protein. 151 3e-36
AY120867-1|AAM55491.1| 752|Homo sapiens MAP/microtubule affinit... 146 8e-35
AY057448-1|AAL23683.1| 752|Homo sapiens MARK4 serine/threonine ... 146 8e-35
AK075272-1|BAC11510.1| 752|Homo sapiens protein ( Homo sapiens ... 146 8e-35
AB088047-1|BAC03375.1| 752|Homo sapiens microtubule affinity-re... 146 8e-35
AB058763-1|BAB47489.1| 689|Homo sapiens KIAA1860 protein protein. 146 8e-35
AB049127-1|BAB39380.1| 688|Homo sapiens MAP/microtubule affinit... 146 8e-35
AB011109-1|BAA25463.2| 698|Homo sapiens KIAA0537 protein protein. 146 1e-34
BC038504-1|AAH38504.1| 783|Homo sapiens SNF1-like kinase protein. 145 1e-34
AK131076-1|BAC85126.1| 764|Homo sapiens FLJ00263 protein protein. 145 1e-34
AB047786-1|BAD74070.1| 783|Homo sapiens serine/threonine protei... 145 1e-34
U64205-1|AAC15093.1| 729|Homo sapiens Cdc25C associated protein... 144 3e-34
M80359-1|AAA59991.1| 713|Homo sapiens protein p78 protein. 144 3e-34
BC024773-1|AAH24773.1| 729|Homo sapiens MAP/microtubule affinit... 144 3e-34
AF465413-1|AAL69982.1| 753|Homo sapiens MAP/microtubule affinit... 144 3e-34
AF387637-1|AAK82367.1| 744|Homo sapiens Ser/Thr protein kinase ... 144 3e-34
X97630-1|CAA66229.1| 745|Homo sapiens serine/threonine protein ... 144 4e-34
BT007342-1|AAP36006.1| 755|Homo sapiens MAP/microtubule affinit... 144 4e-34
BC084540-1|AAH84540.1| 724|Homo sapiens MAP/microtubule affinit... 144 4e-34
BC008771-1|AAH08771.2| 778|Homo sapiens MARK2 protein protein. 144 4e-34
AF387638-1|AAK82368.1| 691|Homo sapiens Ser/Thr protein kinase ... 144 4e-34
AB188493-1|BAD37141.1| 719|Homo sapiens serine/threonine kinase... 144 4e-34
BC114478-1|AAI14479.1| 795|Homo sapiens MARK1 protein protein. 143 7e-34
BC113869-1|AAI13870.1| 795|Homo sapiens MARK1 protein protein. 143 7e-34
AL592406-3|CAH72463.1| 795|Homo sapiens MAP/microtubule affinit... 143 7e-34
AF154845-1|AAF72103.1| 795|Homo sapiens MARK protein. 143 7e-34
BC128510-1|AAI28511.1| 1203|Homo sapiens KIAA0999 protein protein. 142 1e-33
AB023216-1|BAA76843.2| 1371|Homo sapiens KIAA0999 protein protein. 142 1e-33
BC017306-1|AAH17306.1| 628|Homo sapiens NUAK family, SNF1-like ... 140 4e-33
AK074830-1|BAC11234.1| 628|Homo sapiens protein ( Homo sapiens ... 140 4e-33
AP001751-1|BAA95536.1| 786|Homo sapiens SNF1LK protein. 139 9e-33
BC111088-1|AAI11089.1| 252|Homo sapiens TSSK4 protein protein. 138 2e-32
AC005581-1|AAC33487.1| 462|Homo sapiens R31237_1, partial CDS p... 96 2e-30
AJ271722-1|CAB71146.1| 714|Homo sapiens putative serine/threoni... 130 4e-30
D79997-1|BAA11492.2| 656|Homo sapiens KIAA0175 protein. 129 1e-29
BC014039-1|AAH14039.1| 651|Homo sapiens maternal embryonic leuc... 129 1e-29
AL442063-1|CAI16995.2| 651|Homo sapiens maternal embryonic leuc... 129 1e-29
AL354932-1|CAI11034.2| 651|Homo sapiens maternal embryonic leuc... 129 1e-29
AK222811-1|BAD96531.1| 651|Homo sapiens maternal embryonic leuc... 129 1e-29
BC037303-1|AAH37303.1| 550|Homo sapiens PRKAA1 protein protein. 127 5e-29
AB022017-1|BAA36547.1| 550|Homo sapiens AMP-activated protein k... 127 5e-29
EF056019-1|ABK30810.1| 552|Homo sapiens AMP-activated alpha 2 s... 125 2e-28
BC069823-1|AAH69823.1| 552|Homo sapiens AMP-activated protein k... 125 2e-28
BC069740-1|AAH69740.1| 552|Homo sapiens AMP-activated protein k... 125 2e-28
BC069680-1|AAH69680.1| 552|Homo sapiens protein kinase, AMP-act... 125 2e-28
AL035705-2|CAC17574.2| 552|Homo sapiens protein kinase, AMP-act... 125 2e-28
AB183427-1|BAF73615.1| 619|Homo sapiens maternal embryonic leuc... 125 2e-28
U06454-1|AAA64745.1| 552|Homo sapiens AMP-activated protein kin... 123 6e-28
AY505125-1|AAS86443.1| 696|Homo sapiens protein kinase SAD-A pr... 122 1e-27
AY166857-1|AAN87839.1| 668|Homo sapiens serine/threonine protei... 122 1e-27
AK131534-1|BAD18671.1| 766|Homo sapiens protein ( Homo sapiens ... 122 1e-27
AF533880-1|AAP97727.1| 674|Homo sapiens putative serine/threoni... 122 1e-27
AF533879-1|AAP97726.1| 736|Homo sapiens putative serine/threoni... 122 1e-27
AF533878-1|AAP97725.1| 674|Homo sapiens putative serine/threoni... 122 1e-27
AF533877-1|AAP97724.1| 674|Homo sapiens putative serine/threoni... 122 1e-27
AF533876-1|AAP97723.1| 668|Homo sapiens putative serine/threoni... 122 1e-27
U22456-1|AAA64850.1| 174|Homo sapiens AMP-activated protein kin... 122 2e-27
AF159295-1|AAD48007.1| 752|Homo sapiens serine/threonine protei... 122 2e-27
AY505124-1|AAS86442.1| 778|Homo sapiens protein kinase SAD-B pr... 121 3e-27
AY458602-1|AAS10354.1| 778|Homo sapiens SAD1 kinase protein. 121 3e-27
AF479827-1|AAL87698.1| 778|Homo sapiens protein kinase-like pro... 121 3e-27
AF479826-1|AAL87697.1| 794|Homo sapiens putative serine/threoni... 121 3e-27
AF059681-1|AAC77369.1| 275|Homo sapiens serine/threonine kinase... 117 5e-26
BC012622-1|AAH12622.1| 207|Homo sapiens PRKAA1 protein protein. 116 7e-26
BC075064-1|AAH75064.2| 275|Homo sapiens AURKC protein protein. 115 2e-25
AY714054-1|AAU04399.1| 306|Homo sapiens aurora-C protein. 115 2e-25
AY661554-1|AAT64422.1| 290|Homo sapiens aurora/Ipl1-related kin... 115 2e-25
AF054621-1|AAC25955.1| 309|Homo sapiens serine/threonine kinase... 115 2e-25
AB017332-1|BAA76292.1| 309|Homo sapiens Aurora/Ipl1-related kin... 115 2e-25
AB058714-1|BAB47440.1| 715|Homo sapiens KIAA1811 protein protein. 113 5e-25
D43636-1|BAA07744.2| 766|Homo sapiens KIAA0096 protein. 113 9e-25
BC071567-1|AAH71567.1| 765|Homo sapiens SNRK protein protein. 113 9e-25
AK000231-1|BAA91023.1| 244|Homo sapiens protein ( Homo sapiens ... 113 9e-25
BC048980-1|AAH48980.1| 574|Homo sapiens protein kinase, AMP-act... 112 1e-24
BC031231-1|AAH31231.1| 514|Homo sapiens serine/threonine kinase... 112 2e-24
AK093251-1|BAC04109.1| 514|Homo sapiens protein ( Homo sapiens ... 112 2e-24
AJ303380-1|CAC29064.1| 514|Homo sapiens serine/threonine kinase... 112 2e-24
AF226044-1|AAF86944.1| 765|Homo sapiens HSNFRK protein. 112 2e-24
BC036422-1|AAH36422.1| 436|Homo sapiens hypothetical protein MG... 111 3e-24
BC121188-1|AAI21189.1| 185|Homo sapiens KIAA0999 protein protein. 109 1e-23
AJ006701-1|CAA07196.1| 603|Homo sapiens putative serine/threoni... 107 4e-23
BC026158-1|AAH26158.1| 1315|Homo sapiens serine/threonine kinase... 107 6e-23
AF200815-1|AAF97028.1| 1315|Homo sapiens FUSED serine/threonine ... 107 6e-23
AB033104-1|BAA86592.1| 1311|Homo sapiens KIAA1278 protein protein. 107 6e-23
BC017575-1|AAH17575.1| 476|Homo sapiens CHK1 checkpoint homolog... 105 2e-22
BC004202-1|AAH04202.1| 476|Homo sapiens CHEK1 protein protein. 105 2e-22
AK027493-1|BAB55152.1| 638|Homo sapiens protein ( Homo sapiens ... 105 2e-22
AF527555-1|AAM78553.1| 476|Homo sapiens CHK1 checkpoint homolog... 105 2e-22
AF032874-1|AAB88852.1| 476|Homo sapiens protein kinase protein. 105 2e-22
AF016582-1|AAC51736.1| 476|Homo sapiens Chk1 protein. 105 2e-22
AB032387-1|BAA84577.1| 476|Homo sapiens checkpoint kinase protein. 105 2e-22
Y15056-1|CAA75341.1| 556|Homo sapiens PkB kinase protein. 105 2e-22
CR536517-1|CAG38755.1| 556|Homo sapiens PDPK1 protein. 105 2e-22
BC012103-1|AAH12103.1| 556|Homo sapiens 3-phosphoinositide depe... 105 2e-22
AF017995-1|AAC51825.1| 556|Homo sapiens 3-phosphoinositide depe... 105 2e-22
AC005591-1|AAC33797.1| 367|Homo sapiens PkB-like protein. 105 2e-22
AB209835-1|BAD93072.1| 492|Homo sapiens 3-phosphoinositide depe... 105 2e-22
Z92542-3|CAI42485.1| 1030|Homo sapiens cyclin-dependent kinase-l... 104 4e-22
Y15057-1|CAA75342.1| 1030|Homo sapiens STK9 protein protein. 104 4e-22
AY217744-1|AAO64440.1| 1030|Homo sapiens serine/threonine kinase... 104 4e-22
AL109798-1|CAI41159.1| 1030|Homo sapiens cyclin-dependent kinase... 104 4e-22
AF045458-1|AAC32326.1| 1050|Homo sapiens serine/threonine kinase... 104 4e-22
AB018265-1|BAA34442.2| 1066|Homo sapiens KIAA0722 protein protein. 104 4e-22
BC027464-1|AAH27464.1| 403|Homo sapiens aurora kinase A protein. 103 5e-22
BC006423-1|AAH06423.1| 403|Homo sapiens aurora kinase A protein. 103 5e-22
BC002499-1|AAH02499.1| 403|Homo sapiens AURKA protein protein. 103 5e-22
BC001280-1|AAH01280.1| 403|Homo sapiens aurora kinase A protein. 103 5e-22
AL121914-4|CAM45838.1| 347|Homo sapiens aurora kinase A protein. 103 5e-22
AL121914-3|CAC12717.1| 403|Homo sapiens aurora kinase A protein. 103 5e-22
AK222581-1|BAD96301.1| 556|Homo sapiens 3-phosphoinositide depe... 103 5e-22
AK074578-1|BAC11070.1| 426|Homo sapiens protein ( Homo sapiens ... 103 5e-22
AJ785968-1|CAH05056.1| 396|Homo sapiens PDPK2 protein protein. 103 5e-22
AF195947-1|AAF29508.1| 403|Homo sapiens STK15 serine/threonine ... 103 5e-22
AF011468-1|AAC63902.1| 403|Homo sapiens serine/threonine kinase... 103 5e-22
AF008551-1|AAC12708.1| 403|Homo sapiens aurora-related kinase 1... 103 5e-22
BT019534-1|AAV38341.1| 344|Homo sapiens serine/threonine kinase... 103 7e-22
BC080581-1|AAH80581.1| 344|Homo sapiens aurora kinase B protein. 103 7e-22
BC013300-1|AAH13300.2| 371|Homo sapiens AURKB protein protein. 103 7e-22
BC009751-1|AAH09751.1| 344|Homo sapiens aurora kinase B protein. 103 7e-22
BC000442-1|AAH00442.3| 344|Homo sapiens aurora kinase B protein. 103 7e-22
AF008552-1|AAC12709.1| 344|Homo sapiens aurora-related kinase 2... 103 7e-22
AB011450-1|BAA32136.1| 344|Homo sapiens aurora and IPL1-like mi... 103 7e-22
D84212-1|BAA23592.1| 402|Homo sapiens aurora/IPL1-related kinas... 103 9e-22
AB011446-1|BAA82709.1| 343|Homo sapiens Aik2 protein. 102 1e-21
AF004022-1|AAB65786.1| 347|Homo sapiens protein kinase protein. 101 4e-21
AL592406-2|CAH72462.1| 758|Homo sapiens MAP/microtubule affinit... 100 5e-21
AB040910-1|BAA96001.1| 870|Homo sapiens KIAA1477 protein protein. 100 5e-21
BC034988-1|AAH34988.1| 1036|Homo sapiens ULK2 protein protein. 100 1e-20
AF015254-1|AAC98891.1| 347|Homo sapiens serine/threonine kinase... 100 1e-20
AB014523-1|BAA31598.2| 1100|Homo sapiens KIAA0623 protein protein. 100 1e-20
BC114491-1|AAI14492.1| 1189|Homo sapiens NEK1 protein protein. 99 2e-20
BC015147-1|AAH15147.1| 403|Homo sapiens Unknown (protein for IM... 99 2e-20
AB067488-1|BAB67794.1| 1265|Homo sapiens KIAA1901 protein protein. 99 2e-20
BC019916-1|AAH19916.2| 506|Homo sapiens NIMA (never in mitosis ... 97 5e-20
AL139082-7|CAI12895.1| 507|Homo sapiens NIMA (never in mitosis ... 97 5e-20
AK131359-1|BAD18511.1| 510|Homo sapiens protein ( Homo sapiens ... 97 5e-20
AB072828-1|BAC15599.1| 489|Homo sapiens NIMA-related protein ki... 97 5e-20
Z29066-1|CAA82309.1| 445|Homo sapiens protein kinase protein. 97 6e-20
U11050-1|AAA19558.1| 445|Homo sapiens NIMA-like protein kinase ... 97 6e-20
BT019729-1|AAV38534.1| 445|Homo sapiens NIMA (never in mitosis ... 97 6e-20
BC065932-1|AAH65932.1| 214|Homo sapiens NEK2 protein protein. 97 6e-20
BC063885-1|AAH63885.1| 708|Homo sapiens NIMA (never in mitosis ... 97 6e-20
BC052807-1|AAH52807.1| 326|Homo sapiens NEK2 protein protein. 97 6e-20
BC043502-1|AAH43502.2| 445|Homo sapiens NIMA (never in mitosis ... 97 6e-20
AY045701-1|AAK92212.1| 384|Homo sapiens NEK2B protein kinase pr... 97 6e-20
AL356310-2|CAH72901.1| 445|Homo sapiens NIMA (never in mitosis ... 97 6e-20
AL139082-5|CAI12892.2| 708|Homo sapiens NIMA (never in mitosis ... 97 6e-20
AK223353-1|BAD97073.1| 445|Homo sapiens NIMA (never in mitosis ... 97 6e-20
AB183428-1|BAF73616.1| 580|Homo sapiens maternal embryonic luec... 97 6e-20
U56998-1|AAC50637.1| 607|Homo sapiens putative serine/threonine... 97 8e-20
M55284-1|AAA60100.1| 682|Homo sapiens protein kinase C-L protein. 97 8e-20
BC062616-1|AAH62616.1| 424|Homo sapiens protein serine kinase H... 97 8e-20
BC037268-1|AAH37268.1| 683|Homo sapiens protein kinase C, eta p... 97 8e-20
BC013899-1|AAH13899.1| 646|Homo sapiens polo-like kinase 3 (Dro... 97 8e-20
AY764184-1|AAU88146.1| 646|Homo sapiens polo-like kinase 3 (Dro... 97 8e-20
AL592166-11|CAI13006.1| 646|Homo sapiens polo-like kinase 3 (Dr... 97 8e-20
AJ272212-1|CAB91984.1| 424|Homo sapiens protein serine kinase p... 97 8e-20
AB209875-1|BAD93112.1| 621|Homo sapiens polo-like kinase 3 vari... 97 8e-20
Z29067-1|CAA82310.1| 459|Homo sapiens protein kinase protein. 96 1e-19
AJ293866-1|CAC10659.1| 646|Homo sapiens FNK serine/threonine pr... 96 1e-19
L24959-1|AAA18251.1| 473|Homo sapiens calcium/calmodulin depend... 96 1e-19
L17000-1|AAA35639.1| 473|Homo sapiens calcium/calmodulin-depend... 96 1e-19
D30742-1|BAA06403.1| 473|Homo sapiens calmodulin-dependent prot... 96 1e-19
BC025687-1|AAH25687.1| 473|Homo sapiens calcium/calmodulin-depe... 96 1e-19
BC016695-1|AAH16695.2| 503|Homo sapiens CAMK4 protein protein. 96 1e-19
BC041799-1|AAH41799.1| 592|Homo sapiens CDKL3 protein protein. 95 2e-19
AF130372-1|AAF36509.1| 455|Homo sapiens serine-threonine protei... 95 2e-19
BC063585-1|AAH63585.1| 1323|Homo sapiens PAS domain containing s... 95 2e-19
BC043495-1|AAH43495.1| 953|Homo sapiens PASK protein protein. 95 2e-19
BC035745-1|AAH35745.1| 385|Homo sapiens calcium/calmodulin-depe... 95 2e-19
BC032787-1|AAH32787.1| 476|Homo sapiens calcium/calmodulin-depe... 95 2e-19
AY212935-1|AAP29964.1| 460|Homo sapiens CLICK III protein. 95 2e-19
AL731559-2|CAI14675.1| 385|Homo sapiens calcium/calmodulin-depe... 95 2e-19
AL731559-1|CAI14674.1| 357|Homo sapiens calcium/calmodulin-depe... 95 2e-19
AL512783-2|CAH74036.1| 385|Homo sapiens calcium/calmodulin-depe... 95 2e-19
AL512783-1|CAH74035.1| 357|Homo sapiens calcium/calmodulin-depe... 95 2e-19
AL512284-2|CAH71694.1| 385|Homo sapiens calcium/calmodulin-depe... 95 2e-19
AL512284-1|CAH71693.1| 357|Homo sapiens calcium/calmodulin-depe... 95 2e-19
AL391314-2|CAI14410.1| 385|Homo sapiens calcium/calmodulin-depe... 95 2e-19
AL391314-1|CAI14409.1| 357|Homo sapiens calcium/calmodulin-depe... 95 2e-19
AL049688-1|CAB41259.1| 481|Homo sapiens hypothetical protein pr... 95 2e-19
AL023754-3|CAI19991.1| 476|Homo sapiens calcium/calmodulin-depe... 95 2e-19
AF428261-1|AAL28100.1| 476|Homo sapiens calcium/calmodulin-depe... 95 2e-19
AF387103-1|AAK69752.1| 1323|Homo sapiens PAS-kinase protein. 95 2e-19
AF286366-1|AAG00534.1| 357|Homo sapiens CamKI-like protein kina... 95 2e-19
AB081726-1|BAC19846.1| 385|Homo sapiens CaM-kinase I delta prot... 95 2e-19
U24153-1|AAA65442.1| 525|Homo sapiens p21-activated protein kin... 95 3e-19
L41816-1|AAA99458.1| 370|Homo sapiens cam kinase I protein. 95 3e-19
BC106755-1|AAI06756.1| 370|Homo sapiens calcium/calmodulin-depe... 95 3e-19
BC106754-1|AAI06755.1| 370|Homo sapiens calcium/calmodulin-depe... 95 3e-19
U35146-1|AAC50918.1| 493|Homo sapiens p56 KKIAMRE protein kinas... 94 4e-19
BC093981-1|AAH93981.1| 493|Homo sapiens cyclin-dependent kinase... 94 4e-19
BC093646-1|AAH93646.1| 493|Homo sapiens cyclin-dependent kinase... 94 4e-19
X66358-1|CAA47002.1| 358|Homo sapiens serine/threonine protein ... 94 6e-19
BC104977-1|AAI04978.1| 358|Homo sapiens cyclin-dependent kinase... 94 6e-19
BC013879-1|AAH13879.1| 685|Homo sapiens polo-like kinase 2 (Dro... 94 6e-19
AY525548-1|AAS00095.1| 358|Homo sapiens cyclin-dependent kinase... 94 6e-19
AK098163-1|BAC05247.1| 372|Homo sapiens protein ( Homo sapiens ... 94 6e-19
AF223574-1|AAF62897.1| 685|Homo sapiens serum-inducible kinase ... 94 6e-19
AF059617-1|AAC14573.1| 685|Homo sapiens serum-inducible kinase ... 94 6e-19
AB051552-1|BAB21856.1| 608|Homo sapiens KIAA1765 protein protein. 94 6e-19
U79240-1|AAB50198.1| 458|Homo sapiens serine/threonine protein ... 93 7e-19
AF080000-1|AAD23915.1| 802|Homo sapiens RSK-like protein kinase... 93 7e-19
AF074393-1|AAC31171.1| 802|Homo sapiens nuclear mitogen- and st... 93 7e-19
X65293-1|CAA46388.1| 737|Homo sapiens protein kinase C epsilon... 93 1e-18
BC128511-1|AAI28512.1| 1102|Homo sapiens KIAA0999 protein protein. 93 1e-18
BC109034-1|AAI09035.1| 737|Homo sapiens protein kinase C, epsil... 93 1e-18
BC109033-1|AAI09034.1| 737|Homo sapiens protein kinase C, epsil... 93 1e-18
U85755-1|AAD00575.1| 299|Homo sapiens serum-inducible kinase pr... 92 2e-18
M95936-1|AAA58364.1| 481|Homo sapiens protein serine/threonine ... 92 2e-18
M77198-1|AAA36585.1| 520|Homo sapiens rac protein kinase-beta p... 92 2e-18
BC120994-1|AAI20995.1| 481|Homo sapiens v-akt murine thymoma vi... 92 2e-18
AB006972-1|BAB69958.1| 970|Homo sapiens Sak protein. 92 2e-18
Y13115-1|CAA73575.1| 970|Homo sapiens serine/threonine protein ... 92 2e-18
BT020098-1|AAV38901.1| 367|Homo sapiens serum/glucocorticoid re... 92 2e-18
BC036023-1|AAH36023.1| 970|Homo sapiens polo-like kinase 4 (Dro... 92 2e-18
BC032709-1|AAH32709.1| 344|Homo sapiens AKT2 protein protein. 92 2e-18
L33881-1|AAB17011.1| 587|Homo sapiens protein kinase C iota pro... 91 4e-18
L18964-1|AAA60171.1| 587|Homo sapiens protein kinase C iota pro... 91 4e-18
BC127622-1|AAI27623.1| 596|Homo sapiens myosin light chain kina... 91 4e-18
BC092413-1|AAH92413.1| 596|Homo sapiens myosin light chain kina... 91 4e-18
BC069627-1|AAH69627.1| 596|Homo sapiens skeletal myosin light c... 91 4e-18
BC069613-1|AAH69613.1| 524|Homo sapiens p21-activated kinase 2 ... 91 4e-18
BC022016-1|AAH22016.3| 587|Homo sapiens protein kinase C, iota ... 91 4e-18
AY574904-1|AAT81413.1| 510|Homo sapiens regulated in COPD kinas... 91 4e-18
AY574902-1|AAT81411.1| 1215|Homo sapiens regulated in COPD kinas... 91 4e-18
AY574901-1|AAT81410.1| 1328|Homo sapiens regulated in COPD kinas... 91 4e-18
AL160175-10|CAC10006.1| 596|Homo sapiens myosin light chain kin... 91 4e-18
AJ272502-1|CAC81354.1| 596|Homo sapiens skeletal muscle-specifi... 91 4e-18
AF325549-1|AAK15494.1| 596|Homo sapiens skeletal myosin light c... 91 4e-18
X61037-1|CAA43372.1| 417|Homo sapiens human protein kinase B p... 91 5e-18
BC022558-1|AAH22558.1| 344|Homo sapiens CAMK2D protein protein. 91 5e-18
Z98752-7|CAI42315.1| 366|Homo sapiens serum/glucocorticoid regu... 90 7e-18
M63167-1|AAA36539.1| 480|Homo sapiens rac protein kinase-alpha ... 90 7e-18
BC084538-1|AAH84538.1| 480|Homo sapiens v-akt murine thymoma vi... 90 7e-18
BC000479-1|AAH00479.1| 480|Homo sapiens v-akt murine thymoma vi... 90 7e-18
AF283830-1|AAL55732.1| 480|Homo sapiens AKT1 protein. 90 7e-18
BC040457-1|AAH40457.1| 478|Homo sapiens calcium/calmodulin-depe... 90 9e-18
AF145711-1|AAD30559.1| 489|Homo sapiens calcium/calmodulin-depe... 90 9e-18
AF145710-1|AAD30558.1| 478|Homo sapiens calcium/calmodulin-depe... 90 9e-18
AF091486-1|AAD55815.1| 478|Homo sapiens calmodulin-dependent pr... 90 9e-18
AB023185-1|BAA76812.1| 527|Homo sapiens KIAA0968 protein protein. 90 9e-18
Z92868-1|CAB07437.1| 686|Homo sapiens cGMP-dependent protein ki... 89 1e-17
Z92867-1|CAB07436.1| 671|Homo sapiens cGMP-dependent protein ki... 89 1e-17
Y07512-1|CAA68810.1| 686|Homo sapiens protein ( Human mRNA for ... 89 1e-17
D45864-1|BAA08297.1| 671|Homo sapiens cGMP-dependent protein ki... 89 1e-17
CR456418-1|CAG30304.1| 586|Homo sapiens CHEK2 protein. 89 1e-17
BC127090-1|AAI27091.1| 686|Homo sapiens protein kinase, cGMP-de... 89 1e-17
BC032784-1|AAH32784.1| 478|Homo sapiens calcium/calmodulin-depe... 89 1e-17
BC004207-1|AAH04207.1| 543|Homo sapiens CHK2 checkpoint homolog... 89 1e-17
AY987011-1|AAX88806.1| 489|Homo sapiens calcium/calmodulin-depe... 89 1e-17
AY800241-1|AAV41895.1| 543|Homo sapiens CHK2 checkpoint homolog... 89 1e-17
AY551303-1|AAS58464.1| 452|Homo sapiens protein kinase Chk2 tra... 89 1e-17
AY551297-1|AAS58458.1| 586|Homo sapiens protein kinase Chk2 tra... 89 1e-17
AL928686-2|CAI40743.1| 686|Homo sapiens protein kinase, cGMP-de... 89 1e-17
AL928686-1|CAI40742.1| 659|Homo sapiens protein kinase, cGMP-de... 89 1e-17
AL732423-2|CAM17478.1| 788|Homo sapiens mitogen-activated prote... 89 1e-17
AL732423-1|CAM17479.1| 748|Homo sapiens mitogen-activated prote... 89 1e-17
AL732326-2|CAM23143.1| 788|Homo sapiens mitogen-activated prote... 89 1e-17
AL732326-1|CAM23142.1| 748|Homo sapiens mitogen-activated prote... 89 1e-17
AL731537-3|CAI17115.1| 686|Homo sapiens protein kinase, cGMP-de... 89 1e-17
AL731537-2|CAI17114.1| 659|Homo sapiens protein kinase, cGMP-de... 89 1e-17
AL391378-2|CAI39626.1| 686|Homo sapiens protein kinase, cGMP-de... 89 1e-17
AL391378-1|CAI39625.1| 659|Homo sapiens protein kinase, cGMP-de... 89 1e-17
AL157399-2|CAI41305.1| 686|Homo sapiens protein kinase, cGMP-de... 89 1e-17
AL157399-1|CAI41304.1| 659|Homo sapiens protein kinase, cGMP-de... 89 1e-17
AL121825-1|CAH73823.1| 543|Homo sapiens CHK2 checkpoint homolog... 89 1e-17
AL117330-1|CAH73875.1| 543|Homo sapiens CHK2 checkpoint homolog... 89 1e-17
AK131412-1|BAD18559.1| 748|Homo sapiens protein ( Homo sapiens ... 89 1e-17
AK131198-1|BAD18393.1| 706|Homo sapiens protein ( Homo sapiens ... 89 1e-17
AJ252239-1|CAB65123.1| 243|Homo sapiens calcium/calmodulin depe... 89 1e-17
AJ131197-1|CAA10319.1| 543|Homo sapiens protein kinase protein. 89 1e-17
AF217975-1|AAG17218.1| 322|Homo sapiens unknown protein. 89 1e-17
AF174135-1|AAD48504.1| 543|Homo sapiens protein kinase CHK2 pro... 89 1e-17
AF096279-1|AAD11784.1| 543|Homo sapiens HuCds1 kinase protein. 89 1e-17
AF086904-1|AAC83693.1| 543|Homo sapiens protein kinase Chk2 pro... 89 1e-17
AB209288-1|BAD92525.1| 522|Homo sapiens calcium/calmodulin-depe... 89 1e-17
Z98752-8|CAC18509.1| 367|Homo sapiens serum/glucocorticoid regu... 89 2e-17
Z98752-5|CAI42312.1| 427|Homo sapiens serum/glucocorticoid regu... 89 2e-17
Z15108-1|CAA78813.1| 584|Homo sapiens protein kinase C zeta pro... 89 2e-17
L14283-1|AAA36488.1| 592|Homo sapiens protein kinase C zeta pro... 89 2e-17
BT007082-1|AAP35745.1| 592|Homo sapiens protein kinase C, zeta ... 89 2e-17
BC065511-1|AAH65511.1| 367|Homo sapiens SGK2 protein protein. 89 2e-17
BC014270-1|AAH14270.1| 592|Homo sapiens protein kinase C, zeta ... 89 2e-17
BC014037-1|AAH14037.3| 367|Homo sapiens serum/glucocorticoid re... 89 2e-17
BC008058-1|AAH08058.1| 592|Homo sapiens protein kinase C, zeta ... 89 2e-17
AL645703-1|CAI21535.1| 592|Homo sapiens protein kinase C, zeta ... 89 2e-17
AL590822-9|CAI12484.1| 592|Homo sapiens protein kinase C, zeta ... 89 2e-17
AL391845-5|CAI15438.1| 592|Homo sapiens protein kinase C, zeta ... 89 2e-17
AF186470-1|AAG17012.1| 427|Homo sapiens protein kinase protein. 89 2e-17
AF169034-1|AAF12757.2| 367|Homo sapiens protein kinase protein. 89 2e-17
AF071569-1|AAD20442.1| 499|Homo sapiens multifunctional calcium... 89 2e-17
EF560730-1|ABQ59040.1| 686|Homo sapiens PRKG1 protein protein. 89 2e-17
BC112101-1|AAI12102.1| 979|Homo sapiens NIMA related kinase 9 p... 89 2e-17
BC093881-1|AAH93881.1| 979|Homo sapiens NIMA (never in mitosis ... 89 2e-17
AY080896-1|AAL87410.1| 979|Homo sapiens NIMA-family kinase NERC... 89 2e-17
AY048580-1|AAL05428.1| 979|Homo sapiens NIMA-related kinase Nek... 89 2e-17
AC007055-5|AAD31940.1| 312|Homo sapiens protein ( Homo sapiens ... 89 2e-17
AB082526-1|BAC02704.1| 1011|Homo sapiens KIAA1995 protein protein. 89 2e-17
U23460-1|AAC99802.1| 664|Homo sapiens proline rich calmodulin-d... 88 3e-17
BC034511-1|AAH34511.1| 501|Homo sapiens PAK4 protein protein. 88 3e-17
BC025282-1|AAH25282.1| 591|Homo sapiens p21(CDKN1A)-activated k... 88 3e-17
BC019070-1|AAH19070.1| 503|Homo sapiens calcium/calmodulin-depe... 88 3e-17
BC011368-1|AAH11368.1| 591|Homo sapiens p21(CDKN1A)-activated k... 88 3e-17
BC002921-1|AAH02921.1| 426|Homo sapiens p21(CDKN1A)-activated k... 88 3e-17
AY987010-1|AAX88805.1| 393|Homo sapiens serum/glucocorticoid re... 88 3e-17
AK222703-1|BAD96423.1| 542|Homo sapiens calcium/calmodulin-depe... 88 3e-17
AJ252238-1|CAB65122.1| 518|Homo sapiens calcium/calmodulin depe... 88 3e-17
AJ252237-1|CAB65121.1| 479|Homo sapiens calcium/calmodulin depe... 88 3e-17
AJ252236-1|CAB65120.1| 503|Homo sapiens calcium/calmodulin depe... 88 3e-17
AJ011855-1|CAA09820.1| 591|Homo sapiens PAK4 protein protein. 88 3e-17
AF140350-1|AAD42070.1| 449|Homo sapiens calcium/calmodulin-depe... 88 3e-17
AF090421-1|AAC69577.1| 809|Homo sapiens ribosome S6 protein kin... 88 3e-17
AF083419-1|AAD42038.1| 517|Homo sapiens calcium/calmodulin-depe... 88 3e-17
AF081924-1|AAD42037.1| 492|Homo sapiens calcium/calmodulin-depe... 88 3e-17
AF081572-1|AAD42036.1| 503|Homo sapiens calcium/calmodulin-depe... 88 3e-17
AF078803-1|AAD42035.1| 542|Homo sapiens calcium/calmodulin-depe... 88 3e-17
AF005046-1|AAD01210.1| 591|Homo sapiens serine/threonine kinase... 88 3e-17
AB032968-1|BAA86456.1| 467|Homo sapiens KIAA1142 protein protein. 88 3e-17
U25975-1|AAA75468.1| 493|Homo sapiens hPAK65 protein. 88 4e-17
BC020479-1|AAH20479.1| 466|Homo sapiens AKT3 protein protein. 88 4e-17
AY005799-1|AAF91073.1| 465|Homo sapiens protein kinase B gamma ... 88 4e-17
AL928686-3|CAI40744.1| 283|Homo sapiens protein kinase, cGMP-de... 88 4e-17
AL662889-3|CAH73073.1| 479|Homo sapiens v-akt murine thymoma vi... 88 4e-17
AL662889-2|CAH73072.1| 465|Homo sapiens v-akt murine thymoma vi... 88 4e-17
AL592151-2|CAH72892.1| 479|Homo sapiens v-akt murine thymoma vi... 88 4e-17
AL592151-1|CAH72891.1| 465|Homo sapiens v-akt murine thymoma vi... 88 4e-17
AL591721-2|CAH71867.1| 479|Homo sapiens v-akt murine thymoma vi... 88 4e-17
AL591721-1|CAH71866.1| 465|Homo sapiens v-akt murine thymoma vi... 88 4e-17
AL357774-2|CAI40843.1| 544|Homo sapiens p21 (CDKN1A)-activated ... 88 4e-17
AL357774-1|CAI40844.1| 559|Homo sapiens p21 (CDKN1A)-activated ... 88 4e-17
AL117326-3|CAI43167.1| 544|Homo sapiens p21 (CDKN1A)-activated ... 88 4e-17
AL117326-2|CAI43168.1| 559|Homo sapiens p21 (CDKN1A)-activated ... 88 4e-17
AL031117-6|CAI43157.1| 544|Homo sapiens p21 (CDKN1A)-activated ... 88 4e-17
AL031117-5|CAI43158.1| 559|Homo sapiens p21 (CDKN1A)-activated ... 88 4e-17
AK223561-1|BAD97281.1| 765|Homo sapiens ribosomal protein S6 ki... 88 4e-17
AJ245709-1|CAB53537.1| 479|Homo sapiens Akt-3 protein protein. 88 4e-17
AF155651-1|AAF67008.1| 544|Homo sapiens P21-activated kinase 3 ... 88 4e-17
AF135794-1|AAD24196.1| 479|Homo sapiens AKT3 protein kinase pro... 88 4e-17
AF124141-1|AAD29089.1| 479|Homo sapiens protein kinase B gamma ... 88 4e-17
AF085234-1|AAL40392.1| 479|Homo sapiens STK-2 protein. 88 4e-17
AF068864-1|AAC36097.1| 544|Homo sapiens p21-activated kinase 3 ... 88 4e-17
AB102659-1|BAC81128.1| 559|Homo sapiens p21-activated kinase 3 ... 88 4e-17
Y00272-1|CAA68376.1| 297|Homo sapiens protein ( Human cell cycl... 87 5e-17
X05360-1|CAA28963.1| 297|Homo sapiens protein ( Human CDC2 gene... 87 5e-17
BT007004-1|AAP35650.1| 297|Homo sapiens cell division cycle 2, ... 87 5e-17
BC113705-1|AAI13706.1| 692|Homo sapiens NIMA (never in mitosis ... 87 5e-17
BC112240-1|AAI12241.1| 692|Homo sapiens NIMA-related kinase 8 p... 87 5e-17
BC107750-1|AAI07751.1| 225|Homo sapiens CDC2 protein protein. 87 5e-17
BC014563-1|AAH14563.1| 297|Homo sapiens cell division cycle 2, ... 87 5e-17
AY267371-1|AAP04006.1| 692|Homo sapiens NIMA-family kinase NEK8... 87 5e-17
AY242354-1|AAO88243.1| 692|Homo sapiens NIMA-related kinase 12a... 87 5e-17
AK074728-1|BAC11166.1| 240|Homo sapiens protein ( Homo sapiens ... 87 5e-17
AJ010119-1|CAA09009.1| 772|Homo sapiens Ribosomal protein kinas... 87 5e-17
AF512554-1|AAM34793.1| 297|Homo sapiens cell division cycle 2, ... 87 5e-17
AF074715-1|AAC67395.1| 705|Homo sapiens mitogen- and stress-act... 87 5e-17
AL834498-1|CAD39156.1| 716|Homo sapiens hypothetical protein pr... 87 6e-17
AK131477-1|BAD18622.1| 788|Homo sapiens protein ( Homo sapiens ... 87 6e-17
AC093748-1|AAY40983.1| 443|Homo sapiens unknown protein. 87 6e-17
AC017006-1|AAX93253.1| 258|Homo sapiens unknown protein. 87 6e-17
AB209181-1|BAD92418.1| 796|Homo sapiens Hypothetical protein DK... 87 6e-17
Z84486-1|CAI21678.1| 526|Homo sapiens serum/glucocorticoid regu... 87 9e-17
Y10032-1|CAA71138.1| 431|Homo sapiens serine/threonine protein ... 87 9e-17
BC121154-1|AAI21155.1| 465|Homo sapiens v-akt murine thymoma vi... 87 9e-17
BC001263-1|AAH01263.1| 431|Homo sapiens serum/glucocorticoid re... 87 9e-17
AL355881-2|CAH72579.1| 526|Homo sapiens serum/glucocorticoid re... 87 9e-17
AL135839-4|CAI19721.1| 526|Homo sapiens serum/glucocorticoid re... 87 9e-17
AL135839-3|CAI19720.1| 445|Homo sapiens serum/glucocorticoid re... 87 9e-17
AL135839-2|CAI19719.1| 431|Homo sapiens serum/glucocorticoid re... 87 9e-17
AL135839-1|CAI19718.1| 421|Homo sapiens serum/glucocorticoid re... 87 9e-17
AJ000512-1|CAA04146.1| 431|Homo sapiens serine/threonine protei... 87 9e-17
AF153609-1|AAD41091.1| 431|Homo sapiens serine/threonine protei... 87 9e-17
U78876-1|AAB41729.1| 626|Homo sapiens MEK kinase 3 protein. 86 1e-16
U24152-1|AAA65441.1| 545|Homo sapiens p21-activated protein kin... 86 1e-16
DQ454151-1|ABE11554.1| 622|Homo sapiens mitogen-activated prote... 86 1e-16
CR536581-1|CAG38818.1| 429|Homo sapiens SGKL protein. 86 1e-16
BC109299-1|AAI09300.1| 545|Homo sapiens p21/Cdc42/Rac1-activate... 86 1e-16
BC093674-1|AAH93674.1| 626|Homo sapiens mitogen-activated prote... 86 1e-16
BC093672-1|AAH93672.1| 626|Homo sapiens mitogen-activated prote... 86 1e-16
BC090859-1|AAH90859.1| 626|Homo sapiens mitogen-activated prote... 86 1e-16
BC015326-1|AAH15326.1| 496|Homo sapiens serum/glucocorticoid re... 86 1e-16
BC008336-1|AAH08336.1| 594|Homo sapiens Unknown (protein for IM... 86 1e-16
AK223523-1|BAD97243.1| 496|Homo sapiens serum/glucocorticoid re... 86 1e-16
AK027302-1|BAB55026.1| 208|Homo sapiens protein ( Homo sapiens ... 86 1e-16
AF169035-1|AAF12758.1| 429|Homo sapiens protein kinase protein. 86 1e-16
AF071884-1|AAC24716.1| 553|Homo sapiens p21 activated kinase 1B... 86 1e-16
AF042838-1|AAC97073.1| 1495|Homo sapiens MEK kinase 1 protein. 86 1e-16
U67156-1|AAC50894.1| 1374|Homo sapiens mitogen-activated kinase ... 86 1e-16
D86968-1|BAA13204.2| 1626|Homo sapiens KIAA0213 protein. 86 1e-16
D84476-1|BAA12684.2| 1374|Homo sapiens apoptosis signal-regulati... 86 1e-16
D50925-1|BAA09484.2| 1351|Homo sapiens KIAA0135 protein. 86 1e-16
BC146770-1|AAI46771.1| 1558|Homo sapiens mitogen-activated prote... 86 1e-16
BC088829-1|AAH88829.1| 1374|Homo sapiens mitogen-activated prote... 86 1e-16
BC056423-1|AAH56423.1| 214|Homo sapiens ULK3 protein protein. 86 1e-16
BC054503-1|AAH54503.1| 1374|Homo sapiens mitogen-activated prote... 86 1e-16
BC036117-1|AAH36117.1| 214|Homo sapiens ULK3 protein protein. 86 1e-16
AL596452-3|CAI41309.1| 1498|Homo sapiens mitogen-activated prote... 86 1e-16
AL596452-2|CAI41310.1| 1544|Homo sapiens mitogen-activated prote... 86 1e-16
AL591045-2|CAH70639.1| 1498|Homo sapiens mitogen-activated prote... 86 1e-16
AL591045-1|CAH70640.1| 1544|Homo sapiens mitogen-activated prote... 86 1e-16
AL139393-2|CAI20815.1| 1498|Homo sapiens mitogen-activated prote... 86 1e-16
AL139393-1|CAI20816.1| 1544|Homo sapiens mitogen-activated prote... 86 1e-16
AL121933-1|CAI15470.1| 1374|Homo sapiens mitogen-activated prote... 86 1e-16
AL109942-4|CAI21477.1| 1498|Homo sapiens mitogen-activated prote... 86 1e-16
AL109942-3|CAC12766.2| 1544|Homo sapiens mitogen-activated prote... 86 1e-16
AL024508-2|CAI20176.1| 1374|Homo sapiens mitogen-activated prote... 86 1e-16
AF085233-1|AAF27051.2| 496|Homo sapiens SGK-like protein SGKL p... 86 1e-16
AF002715-1|AAB68804.1| 1607|Homo sapiens MAP kinase kinase kinas... 86 1e-16
AB209093-1|BAD92330.1| 1455|Homo sapiens mitogen-activated prote... 86 1e-16
Y11950-1|CAA72694.1| 406|Homo sapiens phosphorylase kinase gamm... 85 3e-16
M31606-1|AAA36442.1| 406|Homo sapiens phosphorylase kinase prot... 85 3e-16
BC002541-1|AAH02541.1| 406|Homo sapiens phosphorylase kinase, g... 85 3e-16
Y15801-1|CAA75792.1| 277|Homo sapiens protein kinase protein. 85 3e-16
Y13927-1|CAA74244.1| 277|Homo sapiens protein kinase protein. 85 3e-16
X73458-1|CAA51837.1| 603|Homo sapiens protein kinase protein. 85 3e-16
U01038-1|AAA56634.1| 603|Homo sapiens pLK protein. 85 3e-16
L19559-1|AAA36659.1| 603|Homo sapiens protein kinase protein. 85 3e-16
BC074852-1|AAH74852.1| 277|Homo sapiens protein kinase, Y-linke... 85 3e-16
BC074851-1|AAH74851.1| 277|Homo sapiens protein kinase, Y-linke... 85 3e-16
BC014846-1|AAH14846.1| 603|Homo sapiens polo-like kinase 1 (Dro... 85 3e-16
BC003002-1|AAH03002.1| 603|Homo sapiens polo-like kinase 1 (Dro... 85 3e-16
BC002369-1|AAH02369.1| 603|Homo sapiens polo-like kinase 1 (Dro... 85 3e-16
AL390029-2|CAI15721.1| 740|Homo sapiens doublecortin and CaM ki... 85 3e-16
AL390029-1|CAI15720.1| 729|Homo sapiens doublecortin and CaM ki... 85 3e-16
AL160392-2|CAH70261.1| 740|Homo sapiens doublecortin and CaM ki... 85 3e-16
AL160392-1|CAH70262.1| 729|Homo sapiens doublecortin and CaM ki... 85 3e-16
AL157760-4|CAH70170.1| 433|Homo sapiens doublecortin and CaM ki... 85 3e-16
AL157760-2|CAH70167.1| 740|Homo sapiens doublecortin and CaM ki... 85 3e-16
AL157760-1|CAH70168.1| 729|Homo sapiens doublecortin and CaM ki... 85 3e-16
AL157694-2|CAH70656.1| 740|Homo sapiens doublecortin and CaM ki... 85 3e-16
AL157694-1|CAH70657.1| 729|Homo sapiens doublecortin and CaM ki... 85 3e-16
AF112472-1|AAD03744.1| 542|Homo sapiens calcium/calmodulin-depe... 85 3e-16
AF112471-1|AAD03743.1| 517|Homo sapiens calcium/calmodulin-depe... 85 3e-16
AB002367-1|BAA20824.2| 794|Homo sapiens KIAA0369 protein. 85 3e-16
U51120-1|AAC50590.1| 545|Homo sapiens PAK1 protein. 84 5e-16
BC024179-1|AAH24179.1| 719|Homo sapiens p21(CDKN1A)-activated k... 84 5e-16
AL353612-1|CAI23529.1| 719|Homo sapiens p21(CDKN1A)-activated k... 84 5e-16
AL135935-1|CAH71126.1| 719|Homo sapiens p21(CDKN1A)-activated k... 84 5e-16
AL031652-1|CAI42211.1| 719|Homo sapiens p21(CDKN1A)-activated k... 84 5e-16
AB040812-1|BAA94194.1| 719|Homo sapiens protein kinase PAK5 pro... 84 5e-16
AB033090-1|BAA86578.1| 753|Homo sapiens KIAA1264 protein protein. 84 5e-16
U66064-1|AAB80848.1| 315|Homo sapiens calcium/calmodulin-depend... 84 6e-16
BC034044-1|AAH34044.1| 527|Homo sapiens calcium/calmodulin-depe... 84 6e-16
AL713896-5|CAI13790.1| 529|Homo sapiens calcium/calmodulin-depe... 84 6e-16
AL713896-4|CAI13789.1| 495|Homo sapiens calcium/calmodulin-depe... 84 6e-16
AL713896-3|CAI13791.1| 527|Homo sapiens calcium/calmodulin-depe... 84 6e-16
AL713896-2|CAI13788.1| 516|Homo sapiens calcium/calmodulin-depe... 84 6e-16
AL596247-5|CAI13965.1| 529|Homo sapiens calcium/calmodulin-depe... 84 6e-16
AL596247-4|CAI13966.1| 495|Homo sapiens calcium/calmodulin-depe... 84 6e-16
AL596247-3|CAI13968.1| 527|Homo sapiens calcium/calmodulin-depe... 84 6e-16
AL596247-2|CAI13967.1| 516|Homo sapiens calcium/calmodulin-depe... 84 6e-16
AF415197-1|AAM33514.1| 566|Homo sapiens calcium/calmodulin-depe... 84 6e-16
U63333-1|AAB05809.1| 433|Homo sapiens serine/threonine protein ... 83 8e-16
L07032-1|AAA60101.1| 706|Homo sapiens protein kinase C-theta pr... 83 8e-16
L01087-1|AAA75571.1| 706|Homo sapiens protein kinase C-theta pr... 83 8e-16
BC113359-1|AAI13360.1| 706|Homo sapiens protein kinase C, theta... 83 8e-16
BC101465-1|AAI01466.1| 706|Homo sapiens protein kinase C, theta... 83 8e-16
BC019334-1|AAH19334.1| 433|Homo sapiens serine/threonine kinase... 83 8e-16
BC007981-1|AAH07981.1| 433|Homo sapiens serine/threonine kinase... 83 8e-16
AL158043-2|CAC12904.2| 706|Homo sapiens protein kinase C, theta... 83 8e-16
AL158043-1|CAI16127.1| 478|Homo sapiens protein kinase C, theta... 83 8e-16
AL137145-2|CAC10200.2| 706|Homo sapiens protein kinase C, theta... 83 8e-16
AL137145-1|CAI15756.1| 478|Homo sapiens protein kinase C, theta... 83 8e-16
AF217978-1|AAG17221.1| 433|Homo sapiens unknown protein. 83 8e-16
AF055327-1|AAC15742.1| 433|Homo sapiens Peutz-Jeghers syndrome ... 83 8e-16
AF035625-1|AAC39527.1| 433|Homo sapiens serine threonine kinase... 83 8e-16
AF032986-1|AAB97833.1| 433|Homo sapiens serine threonine kinase... 83 8e-16
AB209553-1|BAD92790.1| 337|Homo sapiens serine/threonine protei... 83 8e-16
AY355461-1|AAQ84219.1| 347|Homo sapiens MNK1-like kinase 1b pro... 83 1e-15
AL136373-5|CAI14764.1| 424|Homo sapiens MAP kinase interacting ... 83 1e-15
AB000409-1|BAA19885.1| 424|Homo sapiens MNK1 protein. 83 1e-15
X75932-1|CAA53536.1| 603|Homo sapiens Serine/Threonine protein ... 83 1e-15
L20321-1|AAA36658.1| 841|Homo sapiens protein serine/threonine ... 83 1e-15
BC073140-1|AAH73140.1| 414|Homo sapiens MAP kinase interacting ... 83 1e-15
BC063044-1|AAH63044.1| 781|Homo sapiens NEK4 protein protein. 83 1e-15
BC015515-1|AAH15515.1| 451|Homo sapiens Unknown (protein for IM... 83 1e-15
AL137565-1|CAB70816.1| 316|Homo sapiens hypothetical protein pr... 83 1e-15
AF237776-1|AAG26337.1| 414|Homo sapiens MAP kinase-interacting ... 83 1e-15
AF237775-1|AAG26336.1| 465|Homo sapiens MAP kinase-interacting ... 83 1e-15
AC007136-1|AAD21217.1| 472|Homo sapiens Putative map kinase int... 83 1e-15
X80590-1|CAA56681.1| 387|Homo sapiens phosphorylase kinase prot... 82 2e-15
>BC022515-1|AAH22515.1| 367|Homo sapiens testis-specific serine
kinase 1B protein.
Length = 367
Score = 190 bits (464), Expect = 4e-48
Identities = 93/187 (49%), Positives = 131/187 (70%), Gaps = 1/187 (0%)
Frame = +2
Query: 170 LGEMSAEPTATVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFL 349
LGE S + A S+R VAIKII + +AP D+L+KFLPREIE++ L H ++I+
Sbjct: 18 LGEGSYAKVKS-AYSERLKFNVAIKIIDRKKAPADFLEKFLPREIEILAMLNHCSIIKTY 76
Query: 350 QAIETTH-RVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRD 526
+ ET+H +VYIVME A G LL++I+ + E R+ F QL A+ YCH+ VVHRD
Sbjct: 77 EIFETSHGKVYIVMELAVQGDLLELIKTRGALHEDEARKKFHQLSLAIKYCHDLDVVHRD 136
Query: 527 IKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQD 706
+KC+NLL+D NIKLSDF F++ ++ +G ALS+TFCGS AYA+PE+L+G+PY+P+
Sbjct: 137 LKCDNLLLDKDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSPAYAAPEVLQGIPYQPKV 196
Query: 707 SDVWSMG 727
D+WS+G
Sbjct: 197 YDIWSLG 203
>AY028964-1|AAK27734.1| 367|Homo sapiens testis-specific
serine/threonine kinase 1 protein.
Length = 367
Score = 190 bits (464), Expect = 4e-48
Identities = 93/187 (49%), Positives = 131/187 (70%), Gaps = 1/187 (0%)
Frame = +2
Query: 170 LGEMSAEPTATVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFL 349
LGE S + A S+R VAIKII + +AP D+L+KFLPREIE++ L H ++I+
Sbjct: 18 LGEGSYAKVKS-AYSERLKFNVAIKIIDRKKAPADFLEKFLPREIEILAMLNHCSIIKTY 76
Query: 350 QAIETTH-RVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRD 526
+ ET+H +VYIVME A G LL++I+ + E R+ F QL A+ YCH+ VVHRD
Sbjct: 77 EIFETSHGKVYIVMELAVQGDLLELIKTRGALHEDEARKKFHQLSLAIKYCHDLDVVHRD 136
Query: 527 IKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQD 706
+KC+NLL+D NIKLSDF F++ ++ +G ALS+TFCGS AYA+PE+L+G+PY+P+
Sbjct: 137 LKCDNLLLDKDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSPAYAAPEVLQGIPYQPKV 196
Query: 707 SDVWSMG 727
D+WS+G
Sbjct: 197 YDIWSLG 203
>AB284522-1|BAF41973.1| 367|Homo sapiens testis-specific serine
kinase 1 protein.
Length = 367
Score = 190 bits (464), Expect = 4e-48
Identities = 93/187 (49%), Positives = 131/187 (70%), Gaps = 1/187 (0%)
Frame = +2
Query: 170 LGEMSAEPTATVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFL 349
LGE S + A S+R VAIKII + +AP D+L+KFLPREIE++ L H ++I+
Sbjct: 18 LGEGSYAKVKS-AYSERLKFNVAIKIIDRKKAPADFLEKFLPREIEILAMLNHCSIIKTY 76
Query: 350 QAIETTH-RVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRD 526
+ ET+H +VYIVME A G LL++I+ + E R+ F QL A+ YCH+ VVHRD
Sbjct: 77 EIFETSHGKVYIVMELAVQGDLLELIKTRGALHEDEARKKFHQLSLAIKYCHDLDVVHRD 136
Query: 527 IKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQD 706
+KC+NLL+D NIKLSDF F++ ++ +G ALS+TFCGS AYA+PE+L+G+PY+P+
Sbjct: 137 LKCDNLLLDKDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSPAYAAPEVLQGIPYQPKV 196
Query: 707 SDVWSMG 727
D+WS+G
Sbjct: 197 YDIWSLG 203
>CR456587-1|CAG30473.1| 358|Homo sapiens STK22A protein.
Length = 358
Score = 181 bits (440), Expect = 3e-45
Identities = 80/175 (45%), Positives = 122/175 (69%), Gaps = 1/175 (0%)
Frame = +2
Query: 206 ASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTH-RVYI 382
A S+R VA+KII + + P D++++FLPRE++++ + H ++I+ + ET+ R+YI
Sbjct: 29 AYSERLKFNVAVKIIDRKKTPTDFVERFLPREMDILATVNHGSIIKTYEIFETSDGRIYI 88
Query: 383 VMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGL 562
+ME G LL+ I+ + E R+ F+QL AV YCH+ +VHRD+KCENLL+D
Sbjct: 89 IMELGVQGDLLEFIKCQGALHEDVARKMFRQLSSAVKYCHDLDIVHRDLKCENLLLDKDF 148
Query: 563 NIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
NIKLSDFGF++ ++ NG LS+TFCGS AYA+PE+L+ +PY+P+ D+WS+G
Sbjct: 149 NIKLSDFGFSKRCLRDSNGRIILSKTFCGSAAYAAPEVLQSIPYQPKVYDIWSLG 203
>BC037781-1|AAH37781.1| 358|Homo sapiens testis-specific serine
kinase 2 protein.
Length = 358
Score = 181 bits (440), Expect = 3e-45
Identities = 80/175 (45%), Positives = 122/175 (69%), Gaps = 1/175 (0%)
Frame = +2
Query: 206 ASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTH-RVYI 382
A S+R VA+KII + + P D++++FLPRE++++ + H ++I+ + ET+ R+YI
Sbjct: 29 AYSERLKFNVAVKIIDRKKTPTDFVERFLPREMDILATVNHGSIIKTYEIFETSDGRIYI 88
Query: 383 VMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGL 562
+ME G LL+ I+ + E R+ F+QL AV YCH+ +VHRD+KCENLL+D
Sbjct: 89 IMELGVQGDLLEFIKCQGALHEDVARKMFRQLSSAVKYCHDLDIVHRDLKCENLLLDKDF 148
Query: 563 NIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
NIKLSDFGF++ ++ NG LS+TFCGS AYA+PE+L+ +PY+P+ D+WS+G
Sbjct: 149 NIKLSDFGFSKRCLRDSNGRIILSKTFCGSAAYAAPEVLQSIPYQPKVYDIWSLG 203
>AF362953-1|AAK98531.1| 358|Homo sapiens testis specific
serine/threonine kinase 2 protein.
Length = 358
Score = 181 bits (440), Expect = 3e-45
Identities = 80/175 (45%), Positives = 122/175 (69%), Gaps = 1/175 (0%)
Frame = +2
Query: 206 ASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTH-RVYI 382
A S+R VA+KII + + P D++++FLPRE++++ + H ++I+ + ET+ R+YI
Sbjct: 29 AYSERLKFNVAVKIIDRKKTPTDFVERFLPREMDILATVNHGSIIKTYEIFETSDGRIYI 88
Query: 383 VMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGL 562
+ME G LL+ I+ + E R+ F+QL AV YCH+ +VHRD+KCENLL+D
Sbjct: 89 IMELGVQGDLLEFIKCQGALHEDVARKMFRQLSSAVKYCHDLDIVHRDLKCENLLLDKDF 148
Query: 563 NIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
NIKLSDFGF++ ++ NG LS+TFCGS AYA+PE+L+ +PY+P+ D+WS+G
Sbjct: 149 NIKLSDFGFSKRCLRDSNGRIILSKTFCGSAAYAAPEVLQSIPYQPKVYDIWSLG 203
>AB284523-1|BAF41974.1| 358|Homo sapiens testis-specific serine
kinase 2 protein.
Length = 358
Score = 181 bits (440), Expect = 3e-45
Identities = 80/175 (45%), Positives = 122/175 (69%), Gaps = 1/175 (0%)
Frame = +2
Query: 206 ASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTH-RVYI 382
A S+R VA+KII + + P D++++FLPRE++++ + H ++I+ + ET+ R+YI
Sbjct: 29 AYSERLKFNVAVKIIDRKKTPTDFVERFLPREMDILATVNHGSIIKTYEIFETSDGRIYI 88
Query: 383 VMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGL 562
+ME G LL+ I+ + E R+ F+QL AV YCH+ +VHRD+KCENLL+D
Sbjct: 89 IMELGVQGDLLEFIKCQGALHEDVARKMFRQLSSAVKYCHDLDIVHRDLKCENLLLDKDF 148
Query: 563 NIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
NIKLSDFGF++ ++ NG LS+TFCGS AYA+PE+L+ +PY+P+ D+WS+G
Sbjct: 149 NIKLSDFGFSKRCLRDSNGRIILSKTFCGSAAYAAPEVLQSIPYQPKVYDIWSLG 203
>AY461663-1|AAS17971.1| 328|Homo sapiens testis-specific serine
kinase 4 protein.
Length = 328
Score = 176 bits (428), Expect = 8e-44
Identities = 90/183 (49%), Positives = 121/183 (66%), Gaps = 13/183 (7%)
Frame = +2
Query: 218 RHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYA 397
+ VA+KIISK +A DYL KFLPREI+V+K L+H+ LI F +AIE+T RVYI++E A
Sbjct: 46 KQKVMVAVKIISKKKASDDYLNKFLPREIQVMKVLRHKYLINFYRAIESTSRVYIILELA 105
Query: 398 ENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLS 577
+ G +L+ I++ E +WF QL + Y H + +VHRD+K ENLL+D N+K+S
Sbjct: 106 QGGDVLEWIQRYGACSEPLAGKWFSQLTLGIAYLHSKSIVHRDLKLENLLLDKWENVKIS 165
Query: 578 DFGFARGHMKPKN------------GVFA-LSETFCGSYAYASPEILKGVPYRPQDSDVW 718
DFGFA+ M P N F+ LS+T+CGS+AYA PEIL+G+PY P SD W
Sbjct: 166 DFGFAK--MVPSNQPVGCSPSYRQVNCFSHLSQTYCGSFAYACPEILRGLPYNPFLSDTW 223
Query: 719 SMG 727
SMG
Sbjct: 224 SMG 226
>BC035354-1|AAH35354.1| 268|Homo sapiens testis-specific serine
kinase 3 protein.
Length = 268
Score = 172 bits (418), Expect = 1e-42
Identities = 80/175 (45%), Positives = 123/175 (70%), Gaps = 1/175 (0%)
Frame = +2
Query: 206 ASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTH-RVYI 382
A S +H +VAIK+I K P +++++FLPRE+++V+ L H+N+I+ + +E+ ++ +
Sbjct: 27 AFSKKHQRKVAIKVIDKMGGPEEFIQRFLPRELQIVRTLDHKNIIQVYEMLESADGKICL 86
Query: 383 VMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGL 562
VME AE G + D + + E+R + F+Q+VEA+ YCH GV HRD+KCEN L+ G
Sbjct: 87 VMELAEGGDVFDCVLNGGPLPESRAKALFRQMVEAIRYCHGCGVAHRDLKCENALL-QGF 145
Query: 563 NIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
N+KL+DFGFA+ + PK+ LS+TFCGS AYA+PE+L+G+P+ + DVWSMG
Sbjct: 146 NLKLTDFGFAK--VLPKSH-RELSQTFCGSTAYAAPEVLQGIPHDSKKGDVWSMG 197
>AY048701-1|AAL02128.1| 268|Homo sapiens TSSK3 protein.
Length = 268
Score = 172 bits (418), Expect = 1e-42
Identities = 80/175 (45%), Positives = 123/175 (70%), Gaps = 1/175 (0%)
Frame = +2
Query: 206 ASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTH-RVYI 382
A S +H +VAIK+I K P +++++FLPRE+++V+ L H+N+I+ + +E+ ++ +
Sbjct: 27 AFSKKHQRKVAIKVIDKMGGPEEFIQRFLPRELQIVRTLDHKNIIQVYEMLESADGKICL 86
Query: 383 VMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGL 562
VME AE G + D + + E+R + F+Q+VEA+ YCH GV HRD+KCEN L+ G
Sbjct: 87 VMELAEGGDVFDCVLNGGPLPESRAKALFRQMVEAIRYCHGCGVAHRDLKCENALL-QGF 145
Query: 563 NIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
N+KL+DFGFA+ + PK+ LS+TFCGS AYA+PE+L+G+P+ + DVWSMG
Sbjct: 146 NLKLTDFGFAK--VLPKSH-RELSQTFCGSTAYAAPEVLQGIPHDSKKGDVWSMG 197
>AL109945-4|CAI22888.1| 268|Homo sapiens testis-specific serine
kinase 3 protein.
Length = 268
Score = 172 bits (418), Expect = 1e-42
Identities = 80/175 (45%), Positives = 123/175 (70%), Gaps = 1/175 (0%)
Frame = +2
Query: 206 ASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTH-RVYI 382
A S +H +VAIK+I K P +++++FLPRE+++V+ L H+N+I+ + +E+ ++ +
Sbjct: 27 AFSKKHQRKVAIKVIDKMGGPEEFIQRFLPRELQIVRTLDHKNIIQVYEMLESADGKICL 86
Query: 383 VMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGL 562
VME AE G + D + + E+R + F+Q+VEA+ YCH GV HRD+KCEN L+ G
Sbjct: 87 VMELAEGGDVFDCVLNGGPLPESRAKALFRQMVEAIRYCHGCGVAHRDLKCENALL-QGF 145
Query: 563 NIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
N+KL+DFGFA+ + PK+ LS+TFCGS AYA+PE+L+G+P+ + DVWSMG
Sbjct: 146 NLKLTDFGFAK--VLPKSH-RELSQTFCGSTAYAAPEVLQGIPHDSKKGDVWSMG 197
>AF296450-1|AAK97141.1| 268|Homo sapiens testis-specific
serine/threonine kinase 3 protein.
Length = 268
Score = 172 bits (418), Expect = 1e-42
Identities = 80/175 (45%), Positives = 123/175 (70%), Gaps = 1/175 (0%)
Frame = +2
Query: 206 ASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTH-RVYI 382
A S +H +VAIK+I K P +++++FLPRE+++V+ L H+N+I+ + +E+ ++ +
Sbjct: 27 AFSKKHQRKVAIKVIDKMGGPEEFIQRFLPRELQIVRTLDHKNIIQVYEMLESADGKICL 86
Query: 383 VMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGL 562
VME AE G + D + + E+R + F+Q+VEA+ YCH GV HRD+KCEN L+ G
Sbjct: 87 VMELAEGGDVFDCVLNGGPLPESRAKALFRQMVEAIRYCHGCGVAHRDLKCENALL-QGF 145
Query: 563 NIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
N+KL+DFGFA+ + PK+ LS+TFCGS AYA+PE+L+G+P+ + DVWSMG
Sbjct: 146 NLKLTDFGFAK--VLPKSH-RELSQTFCGSTAYAAPEVLQGIPHDSKKGDVWSMG 197
>AK131042-1|BAC85482.1| 338|Homo sapiens protein ( Homo sapiens
cDNA FLJ29008 fis, clone TST06032. ).
Length = 338
Score = 166 bits (403), Expect = 9e-41
Identities = 91/193 (47%), Positives = 121/193 (62%), Gaps = 23/193 (11%)
Frame = +2
Query: 218 RHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYA 397
+ VA+KIISK +A DYL KFLPREI+V+K L+H+ LI F +AIE+T RVYI++E A
Sbjct: 46 KQKVMVAVKIISKKKASDDYLNKFLPREIQVMKVLRHKYLINFYRAIESTSRVYIILELA 105
Query: 398 ENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVH----------RDIKCENLL 547
+ G +L+ IR+ E +WF QL + Y H + +VH RD+K ENLL
Sbjct: 106 QGGDVLEWIRRYGACSEPLAGKWFSQLTLGIAYLHSKSIVHRLMPSLSAAGRDLKLENLL 165
Query: 548 MDHGLNIKLSDFGFARGHMKPKN------------GVFA-LSETFCGSYAYASPEILKGV 688
+D N+K+SDFGFA+ M P N F+ LS+T+CGS+AYA PEIL+G+
Sbjct: 166 LDKWENVKISDFGFAK--MVPSNQPVGCSPSYRQVNCFSHLSQTYCGSFAYACPEILRGL 223
Query: 689 PYRPQDSDVWSMG 727
PY P SD WSMG
Sbjct: 224 PYNPFLSDTWSMG 236
>BC014611-1|AAH14611.1| 273|Homo sapiens testis-specific serine
kinase 6 protein.
Length = 273
Score = 153 bits (371), Expect = 7e-37
Identities = 76/177 (42%), Positives = 116/177 (65%), Gaps = 2/177 (1%)
Frame = +2
Query: 203 VASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTH-RVY 379
VA+S ++ VAIK++ + +AP D++ KFLPRE+ +++G++H +++ + IE + ++Y
Sbjct: 28 VATSKKYKGTVAIKVVDRRRAPPDFVNKFLPRELSILRGVRHPHIVHVFEFIEVCNGKLY 87
Query: 380 IVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD-H 556
IVME A LL ++++ I + R F Q+ AV Y H+ +VHRD+KCEN+L+
Sbjct: 88 IVMEAAAT-DLLQAVQRNGRIPGVQARDLFAQIAGAVRYLHDHHLVHRDLKCENVLLSPD 146
Query: 557 GLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
+KL+DFGF R +G LS T+CGS AYASPE+L G+PY P+ DVWSMG
Sbjct: 147 ERRVKLTDFGFGR----QAHGYPDLSTTYCGSAAYASPEVLLGIPYDPKKYDVWSMG 199
>AK172841-1|BAD18805.1| 406|Homo sapiens protein ( Homo sapiens
cDNA FLJ24002 fis, clone KAIA4350, highly similar to
Homo sapiens serine/threonine protein kinase SSTK
(SSTK). ).
Length = 406
Score = 153 bits (371), Expect = 7e-37
Identities = 76/177 (42%), Positives = 116/177 (65%), Gaps = 2/177 (1%)
Frame = +2
Query: 203 VASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTH-RVY 379
VA+S ++ VAIK++ + +AP D++ KFLPRE+ +++G++H +++ + IE + ++Y
Sbjct: 28 VATSKKYKGTVAIKVVDRRRAPPDFVNKFLPRELSILRGVRHPHIVHVFEFIEVCNGKLY 87
Query: 380 IVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD-H 556
IVME A LL ++++ I + R F Q+ AV Y H+ +VHRD+KCEN+L+
Sbjct: 88 IVMEAAAT-DLLQAVQRNGRIPGVQARDLFAQIAGAVRYLHDHHLVHRDLKCENVLLSPD 146
Query: 557 GLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
+KL+DFGF R +G LS T+CGS AYASPE+L G+PY P+ DVWSMG
Sbjct: 147 ERRVKLTDFGFGR----QAHGYPDLSTTYCGSAAYASPEVLLGIPYDPKKYDVWSMG 199
>AF329483-1|AAK48827.1| 273|Homo sapiens serine/threonine protein
kinase SSTK protein.
Length = 273
Score = 153 bits (371), Expect = 7e-37
Identities = 76/177 (42%), Positives = 116/177 (65%), Gaps = 2/177 (1%)
Frame = +2
Query: 203 VASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTH-RVY 379
VA+S ++ VAIK++ + +AP D++ KFLPRE+ +++G++H +++ + IE + ++Y
Sbjct: 28 VATSKKYKGTVAIKVVDRRRAPPDFVNKFLPRELSILRGVRHPHIVHVFEFIEVCNGKLY 87
Query: 380 IVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD-H 556
IVME A LL ++++ I + R F Q+ AV Y H+ +VHRD+KCEN+L+
Sbjct: 88 IVMEAAAT-DLLQAVQRNGRIPGVQARDLFAQIAGAVRYLHDHHLVHRDLKCENVLLSPD 146
Query: 557 GLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
+KL+DFGF R +G LS T+CGS AYASPE+L G+PY P+ DVWSMG
Sbjct: 147 ERRVKLTDFGFGR----QAHGYPDLSTTYCGSAAYASPEVLLGIPYDPKKYDVWSMG 199
>BC117183-1|AAI17184.1| 926|Homo sapiens SNF1-like kinase 2
protein.
Length = 926
Score = 151 bits (365), Expect = 3e-36
Identities = 74/166 (44%), Positives = 107/166 (64%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
+VAIKII K Q L+K RE++++K L H ++I+ Q +ET +Y+V EYA+NG
Sbjct: 45 EVAIKIIDKSQLDAVNLEKIY-REVQIMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNGE 103
Query: 410 LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGF 589
+ D + ++E+ RR F Q++ AVDYCH R +VHRD+K ENLL+D+ +NIK++DFGF
Sbjct: 104 IFDYLANHGRLNESEARRKFWQILSAVDYCHGRKIVHRDLKAENLLLDNNMNIKIADFGF 163
Query: 590 ARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
K+G L T+CGS YA+PE+ +G Y D+WSMG
Sbjct: 164 GNFF---KSG--ELLATWCGSPPYAAPEVFEGQQYEGPQLDIWSMG 204
>BC113459-1|AAI13460.1| 926|Homo sapiens SNF1-like kinase 2
protein.
Length = 926
Score = 151 bits (365), Expect = 3e-36
Identities = 74/166 (44%), Positives = 107/166 (64%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
+VAIKII K Q L+K RE++++K L H ++I+ Q +ET +Y+V EYA+NG
Sbjct: 45 EVAIKIIDKSQLDAVNLEKIY-REVQIMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNGE 103
Query: 410 LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGF 589
+ D + ++E+ RR F Q++ AVDYCH R +VHRD+K ENLL+D+ +NIK++DFGF
Sbjct: 104 IFDYLANHGRLNESEARRKFWQILSAVDYCHGRKIVHRDLKAENLLLDNNMNIKIADFGF 163
Query: 590 ARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
K+G L T+CGS YA+PE+ +G Y D+WSMG
Sbjct: 164 GNFF---KSG--ELLATWCGSPPYAAPEVFEGQQYEGPQLDIWSMG 204
>AB084424-1|BAB91442.1| 346|Homo sapiens KIAA0781 protein protein.
Length = 346
Score = 151 bits (365), Expect = 3e-36
Identities = 74/166 (44%), Positives = 107/166 (64%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
+VAIKII K Q L+K RE++++K L H ++I+ Q +ET +Y+V EYA+NG
Sbjct: 43 EVAIKIIDKSQLDAVNLEKIY-REVQIMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNGE 101
Query: 410 LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGF 589
+ D + ++E+ RR F Q++ AVDYCH R +VHRD+K ENLL+D+ +NIK++DFGF
Sbjct: 102 IFDYLANHGRLNESEARRKFWQILSAVDYCHGRKIVHRDLKAENLLLDNNMNIKIADFGF 161
Query: 590 ARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
K+G L T+CGS YA+PE+ +G Y D+WSMG
Sbjct: 162 GNFF---KSG--ELLATWCGSPPYAAPEVFEGQQYEGPQLDIWSMG 202
>AB018324-1|BAA34501.3| 950|Homo sapiens KIAA0781 protein protein.
Length = 950
Score = 151 bits (365), Expect = 3e-36
Identities = 74/166 (44%), Positives = 107/166 (64%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
+VAIKII K Q L+K RE++++K L H ++I+ Q +ET +Y+V EYA+NG
Sbjct: 69 EVAIKIIDKSQLDAVNLEKIY-REVQIMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNGE 127
Query: 410 LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGF 589
+ D + ++E+ RR F Q++ AVDYCH R +VHRD+K ENLL+D+ +NIK++DFGF
Sbjct: 128 IFDYLANHGRLNESEARRKFWQILSAVDYCHGRKIVHRDLKAENLLLDNNMNIKIADFGF 187
Query: 590 ARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
K+G L T+CGS YA+PE+ +G Y D+WSMG
Sbjct: 188 GNFF---KSG--ELLATWCGSPPYAAPEVFEGQQYEGPQLDIWSMG 228
>AY120867-1|AAM55491.1| 752|Homo sapiens MAP/microtubule
affinity-regulating kinase-like 1 protein.
Length = 752
Score = 146 bits (354), Expect = 8e-35
Identities = 70/166 (42%), Positives = 104/166 (62%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
+VAIKII K Q L+K RE+ ++KGL H N+++ + IET +Y+VMEYA G
Sbjct: 84 EVAIKIIDKTQLNPSSLQKLF-REVRIMKGLNHPNIVKLFEVIETEKTLYLVMEYASAGE 142
Query: 410 LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGF 589
+ D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+D NIK++DFGF
Sbjct: 143 VFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIADFGF 202
Query: 590 ARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
+ + + + +TFCGS YA+PE+ +G Y + D+WS+G
Sbjct: 203 SN-----EFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLG 243
>AY057448-1|AAL23683.1| 752|Homo sapiens MARK4 serine/threonine
protein kinase protein.
Length = 752
Score = 146 bits (354), Expect = 8e-35
Identities = 70/166 (42%), Positives = 104/166 (62%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
+VAIKII K Q L+K RE+ ++KGL H N+++ + IET +Y+VMEYA G
Sbjct: 84 EVAIKIIDKTQLNPSSLQKLF-REVRIMKGLNHPNIVKLFEVIETEKTLYLVMEYASAGE 142
Query: 410 LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGF 589
+ D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+D NIK++DFGF
Sbjct: 143 VFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIADFGF 202
Query: 590 ARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
+ + + + +TFCGS YA+PE+ +G Y + D+WS+G
Sbjct: 203 SN-----EFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLG 243
>AK075272-1|BAC11510.1| 752|Homo sapiens protein ( Homo sapiens
cDNA FLJ90791 fis, clone THYRO1001593, moderately
similar to PUTATIVE SERINE/THREONINE-PROTEIN KINASE P78
(EC 2.7.1.-). ).
Length = 752
Score = 146 bits (354), Expect = 8e-35
Identities = 70/166 (42%), Positives = 104/166 (62%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
+VAIKII K Q L+K RE+ ++KGL H N+++ + IET +Y+VMEYA G
Sbjct: 84 EVAIKIIDKTQLNPSSLQKLF-REVRIMKGLNHPNIVKLFEVIETEKTLYLVMEYASAGE 142
Query: 410 LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGF 589
+ D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+D NIK++DFGF
Sbjct: 143 VFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIADFGF 202
Query: 590 ARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
+ + + + +TFCGS YA+PE+ +G Y + D+WS+G
Sbjct: 203 SN-----EFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLG 243
>AB088047-1|BAC03375.1| 752|Homo sapiens microtubule
affinity-regulating kinase-like1 protein.
Length = 752
Score = 146 bits (354), Expect = 8e-35
Identities = 70/166 (42%), Positives = 104/166 (62%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
+VAIKII K Q L+K RE+ ++KGL H N+++ + IET +Y+VMEYA G
Sbjct: 84 EVAIKIIDKTQLNPSSLQKLF-REVRIMKGLNHPNIVKLFEVIETEKTLYLVMEYASAGE 142
Query: 410 LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGF 589
+ D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+D NIK++DFGF
Sbjct: 143 VFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIADFGF 202
Query: 590 ARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
+ + + + +TFCGS YA+PE+ +G Y + D+WS+G
Sbjct: 203 SN-----EFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLG 243
>AB058763-1|BAB47489.1| 689|Homo sapiens KIAA1860 protein protein.
Length = 689
Score = 146 bits (354), Expect = 8e-35
Identities = 70/166 (42%), Positives = 104/166 (62%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
+VAIKII K Q L+K RE+ ++KGL H N+++ + IET +Y+VMEYA G
Sbjct: 85 EVAIKIIDKTQLNPSSLQKLF-REVRIMKGLNHPNIVKLFEVIETEKTLYLVMEYASAGE 143
Query: 410 LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGF 589
+ D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+D NIK++DFGF
Sbjct: 144 VFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIADFGF 203
Query: 590 ARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
+ + + + +TFCGS YA+PE+ +G Y + D+WS+G
Sbjct: 204 SN-----EFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLG 244
>AB049127-1|BAB39380.1| 688|Homo sapiens MAP/microtubule
affinity-regulating kinase like 1 protein.
Length = 688
Score = 146 bits (354), Expect = 8e-35
Identities = 70/166 (42%), Positives = 104/166 (62%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
+VAIKII K Q L+K RE+ ++KGL H N+++ + IET +Y+VMEYA G
Sbjct: 84 EVAIKIIDKTQLNPSSLQKLF-REVRIMKGLNHPNIVKLFEVIETEKTLYLVMEYASAGE 142
Query: 410 LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGF 589
+ D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+D NIK++DFGF
Sbjct: 143 VFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIADFGF 202
Query: 590 ARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
+ + + + +TFCGS YA+PE+ +G Y + D+WS+G
Sbjct: 203 SN-----EFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLG 243
>AB011109-1|BAA25463.2| 698|Homo sapiens KIAA0537 protein protein.
Length = 698
Score = 146 bits (353), Expect = 1e-34
Identities = 70/165 (42%), Positives = 100/165 (60%)
Frame = +2
Query: 233 VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSL 412
VAIK I K + + + REIE++ L H ++I + E ++ I+MEYA G L
Sbjct: 118 VAIKSIRKDKIKDEQDMVHIRREIEIMSSLNHPHIISIYEVFENKDKIVIIMEYASKGEL 177
Query: 413 LDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 592
D I + + + E R +F+Q+V AV YCH+ GVVHRD+K EN+L+D NIK++DFG +
Sbjct: 178 YDYISERRRLSERETRHFFRQIVSAVHYCHKNGVVHRDLKLENILLDDNCNIKIADFGLS 237
Query: 593 RGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
+ K K +TFCGS YASPEI+ G PYR + D W++G
Sbjct: 238 NLYQKDK-----FLQTFCGSPLYASPEIVNGRPYRGPEVDSWALG 277
>BC038504-1|AAH38504.1| 783|Homo sapiens SNF1-like kinase protein.
Length = 783
Score = 145 bits (352), Expect = 1e-34
Identities = 72/166 (43%), Positives = 108/166 (65%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
QVAIKII K + L+K RE++++K L H ++I+ Q +ET +YIV E+A+NG
Sbjct: 52 QVAIKIIDKTRLDSSNLEKIY-REVQLMKLLNHPHIIKLYQVMETKDMLYIVTEFAKNGE 110
Query: 410 LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGF 589
+ D + + H+ E R+ F Q++ AV+YCH+ +VHRD+K ENLL+D ++IKL+DFGF
Sbjct: 111 MFDYLTSNGHLSENEARKKFWQILSAVEYCHDHHIVHRDLKTENLLLDGNMDIKLADFGF 170
Query: 590 ARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
+ K+G LS T+CGS YA+PE+ +G Y D+WS+G
Sbjct: 171 GNFY---KSGE-PLS-TWCGSPPYAAPEVFEGKEYEGPQLDIWSLG 211
>AK131076-1|BAC85126.1| 764|Homo sapiens FLJ00263 protein protein.
Length = 764
Score = 145 bits (352), Expect = 1e-34
Identities = 72/166 (43%), Positives = 108/166 (65%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
QVAIKII K + L+K RE++++K L H ++I+ Q +ET +YIV E+A+NG
Sbjct: 33 QVAIKIIDKTRLDSSNLEKIY-REVQLMKLLNHPHIIKLYQVMETKDMLYIVTEFAKNGE 91
Query: 410 LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGF 589
+ D + + H+ E R+ F Q++ AV+YCH+ +VHRD+K ENLL+D ++IKL+DFGF
Sbjct: 92 MFDYLTSNGHLSENEARKKFWQILSAVEYCHDHHIVHRDLKTENLLLDGNMDIKLADFGF 151
Query: 590 ARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
+ K+G LS T+CGS YA+PE+ +G Y D+WS+G
Sbjct: 152 GNFY---KSGE-PLS-TWCGSPPYAAPEVFEGKEYEGPQLDIWSLG 192
>AB047786-1|BAD74070.1| 783|Homo sapiens serine/threonine protein
kinase protein.
Length = 783
Score = 145 bits (352), Expect = 1e-34
Identities = 72/166 (43%), Positives = 108/166 (65%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
QVAIKII K + L+K RE++++K L H ++I+ Q +ET +YIV E+A+NG
Sbjct: 52 QVAIKIIDKTRLDSSNLEKIY-REVQLMKLLNHPHIIKLYQVMETKDMLYIVTEFAKNGE 110
Query: 410 LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGF 589
+ D + + H+ E R+ F Q++ AV+YCH+ +VHRD+K ENLL+D ++IKL+DFGF
Sbjct: 111 MFDYLTSNGHLSENEARKKFWQILSAVEYCHDHHIVHRDLKTENLLLDGNMDIKLADFGF 170
Query: 590 ARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
+ K+G LS T+CGS YA+PE+ +G Y D+WS+G
Sbjct: 171 GNFY---KSGE-PLS-TWCGSPPYAAPEVFEGKEYEGPQLDIWSLG 211
>U64205-1|AAC15093.1| 729|Homo sapiens Cdc25C associated protein
kinase C-TAK1 protein.
Length = 729
Score = 144 bits (349), Expect = 3e-34
Identities = 70/166 (42%), Positives = 103/166 (62%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
+VAIKII K Q L+K RE+ ++K L H N+++ + IET +Y++MEYA G
Sbjct: 81 EVAIKIIDKTQLNPTSLQKLF-REVRIMKILNHPNIVKLFEVIETEKTLYLIMEYASGGE 139
Query: 410 LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGF 589
+ D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+D +NIK++DFGF
Sbjct: 140 VFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGF 199
Query: 590 ARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
+ + V +TFCGS YA+PE+ +G Y + DVWS+G
Sbjct: 200 SN-----EFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLG 240
>M80359-1|AAA59991.1| 713|Homo sapiens protein p78 protein.
Length = 713
Score = 144 bits (349), Expect = 3e-34
Identities = 70/166 (42%), Positives = 103/166 (62%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
+VAIKII K Q L+K RE+ ++K L H N+++ + IET +Y++MEYA G
Sbjct: 81 EVAIKIIDKTQLNPTSLQKLF-REVRIMKILNHPNIVKLFEVIETQKTLYLIMEYASGGK 139
Query: 410 LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGF 589
+ D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+D +NIK++DFGF
Sbjct: 140 VFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGF 199
Query: 590 ARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
+ + V +TFCGS YA+PE+ +G Y + DVWS+G
Sbjct: 200 SN-----EFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLG 240
>BC024773-1|AAH24773.1| 729|Homo sapiens MAP/microtubule
affinity-regulating kinase 3 protein.
Length = 729
Score = 144 bits (349), Expect = 3e-34
Identities = 70/166 (42%), Positives = 103/166 (62%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
+VAIKII K Q L+K RE+ ++K L H N+++ + IET +Y++MEYA G
Sbjct: 81 EVAIKIIDKTQLNPTSLQKLF-REVRIMKILNHPNIVKLFEVIETEKTLYLIMEYASGGE 139
Query: 410 LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGF 589
+ D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+D +NIK++DFGF
Sbjct: 140 VFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGF 199
Query: 590 ARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
+ + V +TFCGS YA+PE+ +G Y + DVWS+G
Sbjct: 200 SN-----EFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLG 240
>AF465413-1|AAL69982.1| 753|Homo sapiens MAP/microtubule
affinity-regulating kinase 3 long isoform protein.
Length = 753
Score = 144 bits (349), Expect = 3e-34
Identities = 70/166 (42%), Positives = 103/166 (62%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
+VAIKII K Q L+K RE+ ++K L H N+++ + IET +Y++MEYA G
Sbjct: 81 EVAIKIIDKTQLNPTSLQKLF-REVRIMKILNHPNIVKLFEVIETEKTLYLIMEYASGGK 139
Query: 410 LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGF 589
+ D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+D +NIK++DFGF
Sbjct: 140 VFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGF 199
Query: 590 ARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
+ + V +TFCGS YA+PE+ +G Y + DVWS+G
Sbjct: 200 SN-----EFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLG 240
>AF387637-1|AAK82367.1| 744|Homo sapiens Ser/Thr protein kinase
PAR-1A protein.
Length = 744
Score = 144 bits (349), Expect = 3e-34
Identities = 70/166 (42%), Positives = 103/166 (62%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
+VAIKII K Q L+K RE+ ++K L H N+++ + IET +Y++MEYA G
Sbjct: 81 EVAIKIIDKTQLNPTSLQKLF-REVRIMKILNHPNIVKLFEVIETEKTLYLIMEYASGGE 139
Query: 410 LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGF 589
+ D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+D +NIK++DFGF
Sbjct: 140 VFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGF 199
Query: 590 ARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
+ + V +TFCGS YA+PE+ +G Y + DVWS+G
Sbjct: 200 SN-----EFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLG 240
>X97630-1|CAA66229.1| 745|Homo sapiens serine/threonine protein
kinase protein.
Length = 745
Score = 144 bits (348), Expect = 4e-34
Identities = 69/166 (41%), Positives = 101/166 (60%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
+VA+KII K Q L+K RE+ ++K L H N+++ + IET +Y+VMEYA G
Sbjct: 45 EVAVKIIDKTQLNSSSLQKLF-REVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGE 103
Query: 410 LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGF 589
+ D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+D +NIK++DFGF
Sbjct: 104 VFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGF 163
Query: 590 ARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
+ +TFCGS YA+PE+ +G Y + DVWS+G
Sbjct: 164 SNEFTFGNK-----LDTFCGSPPYAAPELFQGKKYDGPEVDVWSLG 204
>BT007342-1|AAP36006.1| 755|Homo sapiens MAP/microtubule
affinity-regulating kinase 2 protein.
Length = 755
Score = 144 bits (348), Expect = 4e-34
Identities = 69/166 (41%), Positives = 101/166 (60%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
+VA+KII K Q L+K RE+ ++K L H N+++ + IET +Y+VMEYA G
Sbjct: 45 EVAVKIIDKTQLNSSSLQKLF-REVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGE 103
Query: 410 LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGF 589
+ D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+D +NIK++DFGF
Sbjct: 104 VFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGF 163
Query: 590 ARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
+ +TFCGS YA+PE+ +G Y + DVWS+G
Sbjct: 164 SNEFTFGNK-----LDTFCGSPPYAAPELFQGKKYDGPEVDVWSLG 204
>BC084540-1|AAH84540.1| 724|Homo sapiens MAP/microtubule
affinity-regulating kinase 2 protein.
Length = 724
Score = 144 bits (348), Expect = 4e-34
Identities = 69/166 (41%), Positives = 101/166 (60%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
+VA+KII K Q L+K RE+ ++K L H N+++ + IET +Y+VMEYA G
Sbjct: 78 EVAVKIIDKTQLNSSSLQKLF-REVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGE 136
Query: 410 LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGF 589
+ D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+D +NIK++DFGF
Sbjct: 137 VFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGF 196
Query: 590 ARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
+ +TFCGS YA+PE+ +G Y + DVWS+G
Sbjct: 197 SNEFTFGNK-----LDTFCGSPPYAAPELFQGKKYDGPEVDVWSLG 237
>BC008771-1|AAH08771.2| 778|Homo sapiens MARK2 protein protein.
Length = 778
Score = 144 bits (348), Expect = 4e-34
Identities = 69/166 (41%), Positives = 101/166 (60%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
+VA+KII K Q L+K RE+ ++K L H N+++ + IET +Y+VMEYA G
Sbjct: 68 EVAVKIIDKTQLNSSSLQKLF-REVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGE 126
Query: 410 LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGF 589
+ D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+D +NIK++DFGF
Sbjct: 127 VFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGF 186
Query: 590 ARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
+ +TFCGS YA+PE+ +G Y + DVWS+G
Sbjct: 187 SNEFTFGNK-----LDTFCGSPPYAAPELFQGKKYDGPEVDVWSLG 227
>AF387638-1|AAK82368.1| 691|Homo sapiens Ser/Thr protein kinase
PAR-1Balpha protein.
Length = 691
Score = 144 bits (348), Expect = 4e-34
Identities = 69/166 (41%), Positives = 101/166 (60%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
+VA+KII K Q L+K RE+ ++K L H N+++ + IET +Y+VMEYA G
Sbjct: 45 EVAVKIIDKTQLNSSSLQKLF-REVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGE 103
Query: 410 LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGF 589
+ D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+D +NIK++DFGF
Sbjct: 104 VFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGF 163
Query: 590 ARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
+ +TFCGS YA+PE+ +G Y + DVWS+G
Sbjct: 164 SNEFTFGNK-----LDTFCGSPPYAAPELFQGKKYDGPEVDVWSLG 204
>AB188493-1|BAD37141.1| 719|Homo sapiens serine/threonine kinase
protein.
Length = 719
Score = 144 bits (348), Expect = 4e-34
Identities = 69/166 (41%), Positives = 101/166 (60%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
+VA+KII K Q L+K RE+ ++K L H N+++ + IET +Y+VMEYA G
Sbjct: 78 EVAVKIIDKTQLNSSSLQKLF-REVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGE 136
Query: 410 LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGF 589
+ D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+D +NIK++DFGF
Sbjct: 137 VFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGF 196
Query: 590 ARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
+ +TFCGS YA+PE+ +G Y + DVWS+G
Sbjct: 197 SNEFTFGNK-----LDTFCGSPPYAAPELFQGKKYDGPEVDVWSLG 237
>BC114478-1|AAI14479.1| 795|Homo sapiens MARK1 protein protein.
Length = 795
Score = 143 bits (346), Expect = 7e-34
Identities = 70/166 (42%), Positives = 103/166 (62%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
+VA+KII K Q L+K RE+ ++K L H N+++ + IET +Y+VMEYA G
Sbjct: 85 EVAVKIIDKTQLNPTSLQKLF-REVRIMKILNHPNIVKLFEVIETEKTLYLVMEYASGGE 143
Query: 410 LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGF 589
+ D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+D +NIK++DFGF
Sbjct: 144 VFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDMNIKIADFGF 203
Query: 590 ARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
+ + V +TFCGS YA+PE+ +G Y + DVWS+G
Sbjct: 204 SN-----EFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLG 244
>BC113869-1|AAI13870.1| 795|Homo sapiens MARK1 protein protein.
Length = 795
Score = 143 bits (346), Expect = 7e-34
Identities = 70/166 (42%), Positives = 103/166 (62%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
+VA+KII K Q L+K RE+ ++K L H N+++ + IET +Y+VMEYA G
Sbjct: 85 EVAVKIIDKTQLNPTSLQKLF-REVRIMKILNHPNIVKLFEVIETEKTLYLVMEYASGGE 143
Query: 410 LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGF 589
+ D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+D +NIK++DFGF
Sbjct: 144 VFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDMNIKIADFGF 203
Query: 590 ARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
+ + V +TFCGS YA+PE+ +G Y + DVWS+G
Sbjct: 204 SN-----EFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLG 244
>AL592406-3|CAH72463.1| 795|Homo sapiens MAP/microtubule
affinity-regulating kinase 1 protein.
Length = 795
Score = 143 bits (346), Expect = 7e-34
Identities = 70/166 (42%), Positives = 103/166 (62%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
+VA+KII K Q L+K RE+ ++K L H N+++ + IET +Y+VMEYA G
Sbjct: 85 EVAVKIIDKTQLNPTSLQKLF-REVRIMKILNHPNIVKLFEVIETEKTLYLVMEYASGGE 143
Query: 410 LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGF 589
+ D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+D +NIK++DFGF
Sbjct: 144 VFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDMNIKIADFGF 203
Query: 590 ARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
+ + V +TFCGS YA+PE+ +G Y + DVWS+G
Sbjct: 204 SN-----EFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLG 244
>AF154845-1|AAF72103.1| 795|Homo sapiens MARK protein.
Length = 795
Score = 143 bits (346), Expect = 7e-34
Identities = 70/166 (42%), Positives = 103/166 (62%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
+VA+KII K Q L+K RE+ ++K L H N+++ + IET +Y+VMEYA G
Sbjct: 85 EVAVKIIDKTQLNPTSLQKLF-REVRIMKILNHPNIVKLFEVIETEKTLYLVMEYASGGE 143
Query: 410 LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGF 589
+ D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+D +NIK++DFGF
Sbjct: 144 VFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDMNIKIADFGF 203
Query: 590 ARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
+ + V +TFCGS YA+PE+ +G Y + DVWS+G
Sbjct: 204 SN-----EFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLG 244
>BC128510-1|AAI28511.1| 1203|Homo sapiens KIAA0999 protein protein.
Length = 1203
Score = 142 bits (344), Expect = 1e-33
Identities = 73/166 (43%), Positives = 103/166 (62%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
+VAIKII K Q + LKK RE++++K L H ++IR Q +ET +Y+V EYA G
Sbjct: 33 KVAIKIIDKTQLDEENLKKIF-REVQIMKMLCHPHIIRLYQVMETERMIYLVTEYASGGE 91
Query: 410 LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGF 589
+ D + + E RR FKQ+V AV +CH R +VHRD+K ENLL+D LNIK++DFGF
Sbjct: 92 IFDHLVAHGRMAEKEARRKFKQIVTAVYFCHCRNIVHRDLKAENLLLDANLNIKIADFGF 151
Query: 590 ARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
+ + L +T+CGS YA+PE+ +G Y D+WS+G
Sbjct: 152 SNLFTPGQ-----LLKTWCGSPPYAAPELFEGKEYDGPKVDIWSLG 192
>AB023216-1|BAA76843.2| 1371|Homo sapiens KIAA0999 protein protein.
Length = 1371
Score = 142 bits (344), Expect = 1e-33
Identities = 73/166 (43%), Positives = 103/166 (62%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
+VAIKII K Q + LKK RE++++K L H ++IR Q +ET +Y+V EYA G
Sbjct: 141 KVAIKIIDKTQLDEENLKKIF-REVQIMKMLCHPHIIRLYQVMETERMIYLVTEYASGGE 199
Query: 410 LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGF 589
+ D + + E RR FKQ+V AV +CH R +VHRD+K ENLL+D LNIK++DFGF
Sbjct: 200 IFDHLVAHGRMAEKEARRKFKQIVTAVYFCHCRNIVHRDLKAENLLLDANLNIKIADFGF 259
Query: 590 ARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
+ + L +T+CGS YA+PE+ +G Y D+WS+G
Sbjct: 260 SNLFTPGQ-----LLKTWCGSPPYAAPELFEGKEYDGPKVDIWSLG 300
>BC017306-1|AAH17306.1| 628|Homo sapiens NUAK family, SNF1-like
kinase, 2 protein.
Length = 628
Score = 140 bits (340), Expect = 4e-33
Identities = 70/165 (42%), Positives = 99/165 (60%)
Frame = +2
Query: 233 VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSL 412
VAIK I K + + + REIE++ L H ++I + E + ++ IVMEYA G L
Sbjct: 78 VAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHPHIIAIHEVFENSSKIVIVMEYASRGDL 137
Query: 413 LDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 592
D I + Q + E R +F+Q+V AV YCH+ VVHRD+K EN+L+D NIK++DFG +
Sbjct: 138 YDYISERQQLSEREARHFFRQIVSAVHYCHQNRVVHRDLKLENILLDANGNIKIADFGLS 197
Query: 593 RGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
+ + K +TFCGS YASPEI+ G PY + D WS+G
Sbjct: 198 NLYHQGK-----FLQTFCGSPLYASPEIVNGKPYTGPEVDSWSLG 237
>AK074830-1|BAC11234.1| 628|Homo sapiens protein ( Homo sapiens
cDNA FLJ90349 fis, clone NT2RP2003179, weakly similar to
PUTATIVE SERINE/THREONINE-PROTEIN KINASE EMK (EC
2.7.1.-). ).
Length = 628
Score = 140 bits (340), Expect = 4e-33
Identities = 70/165 (42%), Positives = 99/165 (60%)
Frame = +2
Query: 233 VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSL 412
VAIK I K + + + REIE++ L H ++I + E + ++ IVMEYA G L
Sbjct: 78 VAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHPHIIAIHEVFENSSKIVIVMEYASRGDL 137
Query: 413 LDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 592
D I + Q + E R +F+Q+V AV YCH+ VVHRD+K EN+L+D NIK++DFG +
Sbjct: 138 YDYISERQQLSEREARHFFRQIVSAVHYCHQNRVVHRDLKLENILLDANGNIKIADFGLS 197
Query: 593 RGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
+ + K +TFCGS YASPEI+ G PY + D WS+G
Sbjct: 198 NLYHQGK-----FLQTFCGSPLYASPEIVNGKPYTGPEVDSWSLG 237
>AP001751-1|BAA95536.1| 786|Homo sapiens SNF1LK protein.
Length = 786
Score = 139 bits (337), Expect = 9e-33
Identities = 72/169 (42%), Positives = 108/169 (63%), Gaps = 3/169 (1%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
QVAIKII K + L+K RE++++K L H ++I+ Q +ET +YIV E+A+NG
Sbjct: 52 QVAIKIIDKTRLDSSNLEKIY-REVQLMKLLNHPHIIKLYQVMETKDMLYIVTEFAKNGE 110
Query: 410 LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLS---D 580
+ D + + H+ E R+ F Q++ AV+YCH+ +VHRD+K ENLL+D ++IKL+ D
Sbjct: 111 MFDYLTSNGHLSENEARKKFWQILSAVEYCHDHHIVHRDLKTENLLLDGNMDIKLAGTED 170
Query: 581 FGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
FGF + K+G LS T+CGS YA+PE+ +G Y D+WS+G
Sbjct: 171 FGFGNFY---KSGE-PLS-TWCGSPPYAAPEVFEGKEYEGPQLDIWSLG 214
>BC111088-1|AAI11089.1| 252|Homo sapiens TSSK4 protein protein.
Length = 252
Score = 138 bits (335), Expect = 2e-32
Identities = 71/152 (46%), Positives = 98/152 (64%), Gaps = 13/152 (8%)
Frame = +2
Query: 311 VKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAV 490
+K L+H+ LI F +AIE+T RVYI++E A+ G +L+ I++ E +WF QL +
Sbjct: 1 MKVLRHKYLINFYRAIESTSRVYIILELAQGGDVLEWIQRYGACSEPLAGKWFSQLTLGI 60
Query: 491 DYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKN------------GVFA-L 631
Y H + +VHRD+K ENLL+D N+K+SDFGFA+ M P N F+ L
Sbjct: 61 AYLHSKSIVHRDLKLENLLLDKWENVKISDFGFAK--MVPSNQPVGCSPSYRQVNCFSHL 118
Query: 632 SETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
S+T+CGS+AYA PEIL+G+PY P SD WSMG
Sbjct: 119 SQTYCGSFAYACPEILRGLPYNPFLSDTWSMG 150
>AC005581-1|AAC33487.1| 462|Homo sapiens R31237_1, partial CDS
protein.
Length = 462
Score = 96.3 bits (229), Expect(2) = 2e-30
Identities = 44/108 (40%), Positives = 67/108 (62%)
Frame = +2
Query: 404 GSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDF 583
G + D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+D NIK++DF
Sbjct: 171 GEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIADF 230
Query: 584 GFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
GF+ + + + +TFCGS YA+PE+ +G Y + D+WS+G
Sbjct: 231 GFSN-----EFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLG 273
Score = 56.8 bits (131), Expect(2) = 2e-30
Identities = 27/59 (45%), Positives = 38/59 (64%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENG 406
+VAIKII K Q L+K RE+ ++KGL H N+++ + IET +Y+VMEYA G
Sbjct: 84 EVAIKIIDKTQLNPSSLQKLF-REVRIMKGLNHPNIVKLFEVIETEKTLYLVMEYASAG 141
>AJ271722-1|CAB71146.1| 714|Homo sapiens putative serine/threonine
protein kinase MAK-V protein.
Length = 714
Score = 130 bits (315), Expect = 4e-30
Identities = 71/170 (41%), Positives = 106/170 (62%), Gaps = 4/170 (2%)
Frame = +2
Query: 230 QVAIKIISKFQAPGD-YLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENG 406
+VAIK+I K +A D Y+ K L RE ++ + ++H N+ + L +ET + Y+VME G
Sbjct: 87 KVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRHPNITQLLDILETENSYYLVMELCPGG 146
Query: 407 SLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFG 586
+L+ I + + ++E+ RR+ +QL+ AV++ H GVVHRD+K ENLL+D NIKL DFG
Sbjct: 147 NLMHKIYEKKRLEESEARRYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFG 206
Query: 587 FARGHMKPKNGVFALSETF---CGSYAYASPEILKGVPYRPQDSDVWSMG 727
+ G+ S+ F CGS AYA+PE+L Y P+ DVWS+G
Sbjct: 207 LSN-----CAGILGYSDPFSTQCGSPAYAAPELLARKKYGPK-IDVWSIG 250
>D79997-1|BAA11492.2| 656|Homo sapiens KIAA0175 protein.
Length = 656
Score = 129 bits (311), Expect = 1e-29
Identities = 66/165 (40%), Positives = 95/165 (57%)
Frame = +2
Query: 233 VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSL 412
VAIKI+ K D + + EIE +K L+H+++ + +ET +++++V+EY G L
Sbjct: 42 VAIKIMDKNTLGSDLPR--IKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGEL 99
Query: 413 LDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 592
D I + E R F+Q+V AV Y H +G HRD+K ENLL D +KL DFG
Sbjct: 100 FDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLC 159
Query: 593 RGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
KPK +T CGS AYA+PE+++G Y ++DVWSMG
Sbjct: 160 ---AKPKGNKDYHLQTCCGSLAYAAPELIQGKSYLGSEADVWSMG 201
>BC014039-1|AAH14039.1| 651|Homo sapiens maternal embryonic leucine
zipper kinase protein.
Length = 651
Score = 129 bits (311), Expect = 1e-29
Identities = 66/165 (40%), Positives = 95/165 (57%)
Frame = +2
Query: 233 VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSL 412
VAIKI+ K D + + EIE +K L+H+++ + +ET +++++V+EY G L
Sbjct: 37 VAIKIMDKNTLGSDLPR--IKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGEL 94
Query: 413 LDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 592
D I + E R F+Q+V AV Y H +G HRD+K ENLL D +KL DFG
Sbjct: 95 FDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLC 154
Query: 593 RGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
KPK +T CGS AYA+PE+++G Y ++DVWSMG
Sbjct: 155 ---AKPKGNKDYHLQTCCGSLAYAAPELIQGKSYLGSEADVWSMG 196
>AL442063-1|CAI16995.2| 651|Homo sapiens maternal embryonic leucine
zipper kinase protein.
Length = 651
Score = 129 bits (311), Expect = 1e-29
Identities = 66/165 (40%), Positives = 95/165 (57%)
Frame = +2
Query: 233 VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSL 412
VAIKI+ K D + + EIE +K L+H+++ + +ET +++++V+EY G L
Sbjct: 37 VAIKIMDKNTLGSDLPR--IKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGEL 94
Query: 413 LDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 592
D I + E R F+Q+V AV Y H +G HRD+K ENLL D +KL DFG
Sbjct: 95 FDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLC 154
Query: 593 RGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
KPK +T CGS AYA+PE+++G Y ++DVWSMG
Sbjct: 155 ---AKPKGNKDYHLQTCCGSLAYAAPELIQGKSYLGSEADVWSMG 196
>AL354932-1|CAI11034.2| 651|Homo sapiens maternal embryonic leucine
zipper kinase protein.
Length = 651
Score = 129 bits (311), Expect = 1e-29
Identities = 66/165 (40%), Positives = 95/165 (57%)
Frame = +2
Query: 233 VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSL 412
VAIKI+ K D + + EIE +K L+H+++ + +ET +++++V+EY G L
Sbjct: 37 VAIKIMDKNTLGSDLPR--IKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGEL 94
Query: 413 LDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 592
D I + E R F+Q+V AV Y H +G HRD+K ENLL D +KL DFG
Sbjct: 95 FDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLC 154
Query: 593 RGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
KPK +T CGS AYA+PE+++G Y ++DVWSMG
Sbjct: 155 ---AKPKGNKDYHLQTCCGSLAYAAPELIQGKSYLGSEADVWSMG 196
>AK222811-1|BAD96531.1| 651|Homo sapiens maternal embryonic leucine
zipper kinase variant protein.
Length = 651
Score = 129 bits (311), Expect = 1e-29
Identities = 66/165 (40%), Positives = 95/165 (57%)
Frame = +2
Query: 233 VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSL 412
VAIKI+ K D + + EIE +K L+H+++ + +ET +++++V+EY G L
Sbjct: 37 VAIKIMDKNTLGSDLPR--IKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGEL 94
Query: 413 LDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 592
D I + E R F+Q+V AV Y H +G HRD+K ENLL D +KL DFG
Sbjct: 95 FDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLC 154
Query: 593 RGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
KPK +T CGS AYA+PE+++G Y ++DVWSMG
Sbjct: 155 ---AKPKGNKDYHLQTCCGSLAYAAPELIQGKSYLGSEADVWSMG 196
>BC037303-1|AAH37303.1| 550|Homo sapiens PRKAA1 protein protein.
Length = 550
Score = 127 bits (306), Expect = 5e-29
Identities = 64/166 (38%), Positives = 99/166 (59%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
+VA+KI+++ + + + REI+ +K +H ++I+ Q I T +++VMEY G
Sbjct: 43 KVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGE 102
Query: 410 LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGF 589
L D I K+ +DE RR F+Q++ VDYCH VVHRD+K EN+L+D +N K++DFG
Sbjct: 103 LFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGL 162
Query: 590 ARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
+ +G F T CGS YA+PE++ G Y + D+WS G
Sbjct: 163 SN---MMSDGEFL--RTSCGSPNYAAPEVISGRLYAGPEVDIWSSG 203
>AB022017-1|BAA36547.1| 550|Homo sapiens AMP-activated protein
kinase alpha-1 protein.
Length = 550
Score = 127 bits (306), Expect = 5e-29
Identities = 64/166 (38%), Positives = 99/166 (59%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
+VA+KI+++ + + + REI+ +K +H ++I+ Q I T +++VMEY G
Sbjct: 43 KVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGE 102
Query: 410 LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGF 589
L D I K+ +DE RR F+Q++ VDYCH VVHRD+K EN+L+D +N K++DFG
Sbjct: 103 LFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGL 162
Query: 590 ARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
+ +G F T CGS YA+PE++ G Y + D+WS G
Sbjct: 163 SN---MMSDGEFL--RTSCGSPNYAAPEVISGRLYAGPEVDIWSSG 203
>EF056019-1|ABK30810.1| 552|Homo sapiens AMP-activated alpha 2
subunit protein.
Length = 552
Score = 125 bits (301), Expect = 2e-28
Identities = 64/166 (38%), Positives = 98/166 (59%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
+VA+KI+++ + + + REI+ +K +H ++I+ Q I T ++VMEY G
Sbjct: 41 KVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGE 100
Query: 410 LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGF 589
L D I K ++E RR F+Q++ AVDYCH VVHRD+K EN+L+D +N K++DFG
Sbjct: 101 LFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGL 160
Query: 590 ARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
+ +G F T CGS YA+PE++ G Y + D+WS G
Sbjct: 161 SN---MMSDGEFL--RTSCGSPNYAAPEVISGRLYAGPEVDIWSCG 201
>BC069823-1|AAH69823.1| 552|Homo sapiens AMP-activated protein
kinase alpha 2 catalytic subunit protein.
Length = 552
Score = 125 bits (301), Expect = 2e-28
Identities = 64/166 (38%), Positives = 98/166 (59%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
+VA+KI+++ + + + REI+ +K +H ++I+ Q I T ++VMEY G
Sbjct: 41 KVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGE 100
Query: 410 LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGF 589
L D I K ++E RR F+Q++ AVDYCH VVHRD+K EN+L+D +N K++DFG
Sbjct: 101 LFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGL 160
Query: 590 ARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
+ +G F T CGS YA+PE++ G Y + D+WS G
Sbjct: 161 SN---MMSDGEFL--RTSCGSPNYAAPEVISGRLYAGPEVDIWSCG 201
>BC069740-1|AAH69740.1| 552|Homo sapiens AMP-activated protein
kinase alpha 2 catalytic subunit protein.
Length = 552
Score = 125 bits (301), Expect = 2e-28
Identities = 64/166 (38%), Positives = 98/166 (59%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
+VA+KI+++ + + + REI+ +K +H ++I+ Q I T ++VMEY G
Sbjct: 41 KVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGE 100
Query: 410 LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGF 589
L D I K ++E RR F+Q++ AVDYCH VVHRD+K EN+L+D +N K++DFG
Sbjct: 101 LFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGL 160
Query: 590 ARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
+ +G F T CGS YA+PE++ G Y + D+WS G
Sbjct: 161 SN---MMSDGEFL--RTSCGSPNYAAPEVISGRLYAGPEVDIWSCG 201
>BC069680-1|AAH69680.1| 552|Homo sapiens protein kinase,
AMP-activated, alpha 2 catalytic subunit protein.
Length = 552
Score = 125 bits (301), Expect = 2e-28
Identities = 64/166 (38%), Positives = 98/166 (59%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
+VA+KI+++ + + + REI+ +K +H ++I+ Q I T ++VMEY G
Sbjct: 41 KVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGE 100
Query: 410 LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGF 589
L D I K ++E RR F+Q++ AVDYCH VVHRD+K EN+L+D +N K++DFG
Sbjct: 101 LFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGL 160
Query: 590 ARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
+ +G F T CGS YA+PE++ G Y + D+WS G
Sbjct: 161 SN---MMSDGEFL--RTSCGSPNYAAPEVISGRLYAGPEVDIWSCG 201
>AL035705-2|CAC17574.2| 552|Homo sapiens protein kinase,
AMP-activated, alpha 2 catalytic subunit protein.
Length = 552
Score = 125 bits (301), Expect = 2e-28
Identities = 64/166 (38%), Positives = 98/166 (59%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
+VA+KI+++ + + + REI+ +K +H ++I+ Q I T ++VMEY G
Sbjct: 41 KVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGE 100
Query: 410 LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGF 589
L D I K ++E RR F+Q++ AVDYCH VVHRD+K EN+L+D +N K++DFG
Sbjct: 101 LFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGL 160
Query: 590 ARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
+ +G F T CGS YA+PE++ G Y + D+WS G
Sbjct: 161 SN---MMSDGEFL--RTSCGSPNYAAPEVISGRLYAGPEVDIWSCG 201
>AB183427-1|BAF73615.1| 619|Homo sapiens maternal embryonic leucine
zipper kinase v2 protein.
Length = 619
Score = 125 bits (301), Expect = 2e-28
Identities = 62/149 (41%), Positives = 88/149 (59%), Gaps = 3/149 (2%)
Frame = +2
Query: 290 LPR---EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGR 460
LPR EIE +K L+H+++ + +ET +++++V+EY G L D I + E R
Sbjct: 19 LPRIKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETR 78
Query: 461 RWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSET 640
F+Q+V AV Y H +G HRD+K ENLL D +KL DFG KPK +T
Sbjct: 79 VVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLC---AKPKGNKDYHLQT 135
Query: 641 FCGSYAYASPEILKGVPYRPQDSDVWSMG 727
CGS AYA+PE+++G Y ++DVWSMG
Sbjct: 136 CCGSLAYAAPELIQGKSYLGSEADVWSMG 164
>U06454-1|AAA64745.1| 552|Homo sapiens AMP-activated protein kinase
protein.
Length = 552
Score = 123 bits (297), Expect = 6e-28
Identities = 63/166 (37%), Positives = 97/166 (58%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
+VA+KI+++ + + + REI+ +K +H ++I+ Q I T ++VMEY G
Sbjct: 41 KVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGE 100
Query: 410 LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGF 589
L D I K ++E RR F+Q++ AVDYCH VVHRD+K EN+L+D +N K++DFG
Sbjct: 101 LFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGL 160
Query: 590 ARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
+ +G F T CGS Y +PE++ G Y + D+WS G
Sbjct: 161 SN---MMSDGEFL--RTSCGSPNYTAPEVISGRLYAGPEVDIWSCG 201
>AY505125-1|AAS86443.1| 696|Homo sapiens protein kinase SAD-A
protein.
Length = 696
Score = 122 bits (295), Expect = 1e-27
Identities = 61/168 (36%), Positives = 100/168 (59%), Gaps = 1/168 (0%)
Frame = +2
Query: 227 CQ-VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAEN 403
CQ VAIKI+++ + L K + REI ++K ++H ++++ E +Y+V+E+
Sbjct: 42 CQKVAIKIVNREKLSESVLMK-VEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSG 100
Query: 404 GSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDF 583
G L D + K + R++F+Q++ A+D+CH + HRD+K ENLL+D NI+++DF
Sbjct: 101 GELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIRIADF 160
Query: 584 GFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
G A + +L ET CGS YA PE+++G Y + +DVWS G
Sbjct: 161 GMASLQVGD-----SLLETSCGSPHYACPEVIRGEKYDGRKADVWSCG 203
>AY166857-1|AAN87839.1| 668|Homo sapiens serine/threonine protein
kinase isoform protein.
Length = 668
Score = 122 bits (295), Expect = 1e-27
Identities = 61/168 (36%), Positives = 100/168 (59%), Gaps = 1/168 (0%)
Frame = +2
Query: 227 CQ-VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAEN 403
CQ VAIKI+++ + L K + REI ++K ++H ++++ E +Y+V+E+
Sbjct: 42 CQKVAIKIVNREKLSESVLMK-VEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSG 100
Query: 404 GSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDF 583
G L D + K + R++F+Q++ A+D+CH + HRD+K ENLL+D NI+++DF
Sbjct: 101 GELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIRIADF 160
Query: 584 GFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
G A + +L ET CGS YA PE+++G Y + +DVWS G
Sbjct: 161 GMASLQVGD-----SLLETSCGSPHYACPEVIRGEKYDGRKADVWSCG 203
>AK131534-1|BAD18671.1| 766|Homo sapiens protein ( Homo sapiens
cDNA FLJ16763 fis, clone BRAMY3018357, weakly similar
to SNF1-related protein kinase KIN10 (EC 2.7.1.-). ).
Length = 766
Score = 122 bits (295), Expect = 1e-27
Identities = 61/168 (36%), Positives = 100/168 (59%), Gaps = 1/168 (0%)
Frame = +2
Query: 227 CQ-VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAEN 403
CQ VAIKI+++ + L K + REI ++K ++H ++++ E +Y+V+E+
Sbjct: 88 CQKVAIKIVNREKLSESVLMK-VEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSG 146
Query: 404 GSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDF 583
G L D + K + R++F+Q++ A+D+CH + HRD+K ENLL+D NI+++DF
Sbjct: 147 GELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIRIADF 206
Query: 584 GFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
G A + +L ET CGS YA PE+++G Y + +DVWS G
Sbjct: 207 GMASLQVGD-----SLLETSCGSPHYACPEVIRGEKYDGRKADVWSCG 249
>AF533880-1|AAP97727.1| 674|Homo sapiens putative serine/threonine
protein kinase variant B3 protein.
Length = 674
Score = 122 bits (295), Expect = 1e-27
Identities = 61/168 (36%), Positives = 100/168 (59%), Gaps = 1/168 (0%)
Frame = +2
Query: 227 CQ-VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAEN 403
CQ VAIKI+++ + L K + REI ++K ++H ++++ E +Y+V+E+
Sbjct: 42 CQKVAIKIVNREKLSESVLMK-VEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSG 100
Query: 404 GSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDF 583
G L D + K + R++F+Q++ A+D+CH + HRD+K ENLL+D NI+++DF
Sbjct: 101 GELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIRIADF 160
Query: 584 GFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
G A + +L ET CGS YA PE+++G Y + +DVWS G
Sbjct: 161 GMASLQVGD-----SLLETSCGSPHYACPEVIRGEKYDGRKADVWSCG 203
>AF533879-1|AAP97726.1| 736|Homo sapiens putative serine/threonine
protein kinase variant C protein.
Length = 736
Score = 122 bits (295), Expect = 1e-27
Identities = 61/168 (36%), Positives = 100/168 (59%), Gaps = 1/168 (0%)
Frame = +2
Query: 227 CQ-VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAEN 403
CQ VAIKI+++ + L K + REI ++K ++H ++++ E +Y+V+E+
Sbjct: 42 CQKVAIKIVNREKLSESVLMK-VEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSG 100
Query: 404 GSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDF 583
G L D + K + R++F+Q++ A+D+CH + HRD+K ENLL+D NI+++DF
Sbjct: 101 GELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIRIADF 160
Query: 584 GFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
G A + +L ET CGS YA PE+++G Y + +DVWS G
Sbjct: 161 GMASLQVGD-----SLLETSCGSPHYACPEVIRGEKYDGRKADVWSCG 203
>AF533878-1|AAP97725.1| 674|Homo sapiens putative serine/threonine
protein kinase variant B2 protein.
Length = 674
Score = 122 bits (295), Expect = 1e-27
Identities = 61/168 (36%), Positives = 100/168 (59%), Gaps = 1/168 (0%)
Frame = +2
Query: 227 CQ-VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAEN 403
CQ VAIKI+++ + L K + REI ++K ++H ++++ E +Y+V+E+
Sbjct: 42 CQKVAIKIVNREKLSESVLMK-VEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSG 100
Query: 404 GSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDF 583
G L D + K + R++F+Q++ A+D+CH + HRD+K ENLL+D NI+++DF
Sbjct: 101 GELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIRIADF 160
Query: 584 GFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
G A + +L ET CGS YA PE+++G Y + +DVWS G
Sbjct: 161 GMASLQVGD-----SLLETSCGSPHYACPEVIRGEKYDGRKADVWSCG 203
>AF533877-1|AAP97724.1| 674|Homo sapiens putative serine/threonine
protein kinase variant B1 protein.
Length = 674
Score = 122 bits (295), Expect = 1e-27
Identities = 61/168 (36%), Positives = 100/168 (59%), Gaps = 1/168 (0%)
Frame = +2
Query: 227 CQ-VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAEN 403
CQ VAIKI+++ + L K + REI ++K ++H ++++ E +Y+V+E+
Sbjct: 42 CQKVAIKIVNREKLSESVLMK-VEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSG 100
Query: 404 GSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDF 583
G L D + K + R++F+Q++ A+D+CH + HRD+K ENLL+D NI+++DF
Sbjct: 101 GELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIRIADF 160
Query: 584 GFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
G A + +L ET CGS YA PE+++G Y + +DVWS G
Sbjct: 161 GMASLQVGD-----SLLETSCGSPHYACPEVIRGEKYDGRKADVWSCG 203
>AF533876-1|AAP97723.1| 668|Homo sapiens putative serine/threonine
protein kinase variant A protein.
Length = 668
Score = 122 bits (295), Expect = 1e-27
Identities = 61/168 (36%), Positives = 100/168 (59%), Gaps = 1/168 (0%)
Frame = +2
Query: 227 CQ-VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAEN 403
CQ VAIKI+++ + L K + REI ++K ++H ++++ E +Y+V+E+
Sbjct: 42 CQKVAIKIVNREKLSESVLMK-VEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSG 100
Query: 404 GSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDF 583
G L D + K + R++F+Q++ A+D+CH + HRD+K ENLL+D NI+++DF
Sbjct: 101 GELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIRIADF 160
Query: 584 GFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
G A + +L ET CGS YA PE+++G Y + +DVWS G
Sbjct: 161 GMASLQVGD-----SLLETSCGSPHYACPEVIRGEKYDGRKADVWSCG 203
>U22456-1|AAA64850.1| 174|Homo sapiens AMP-activated protein kinase
homolog protein.
Length = 174
Score = 122 bits (293), Expect = 2e-27
Identities = 62/163 (38%), Positives = 97/163 (59%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
+VA+KI+++ + + + REI+ +K +H ++I+ Q I T +++VMEY G
Sbjct: 17 KVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGE 76
Query: 410 LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGF 589
L D I K+ +DE RR F+Q++ VDYCH VVHRD+K EN+L+D +N K++DFG
Sbjct: 77 LFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGL 136
Query: 590 ARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVW 718
+ +G F T CGS YA+PE++ G Y + D+W
Sbjct: 137 SN---MMSDGEFL--RTSCGSPNYAAPEVISGRLYVGPEVDLW 174
>AF159295-1|AAD48007.1| 752|Homo sapiens serine/threonine protein
kinase Kp78 splice variant CTAK75a protein.
Length = 752
Score = 122 bits (293), Expect = 2e-27
Identities = 70/189 (37%), Positives = 103/189 (54%), Gaps = 23/189 (12%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
+VAIKII K Q L+K RE+ ++K L H N+++ + IET +Y++MEYA G
Sbjct: 81 EVAIKIIDKTQLNPTSLQKLF-REVRIMKILNHPNIVKLFEVIETEKTLYLIMEYASGGE 139
Query: 410 LLDIIRKDQHIDETRGRRWFKQ-----------------------LVEAVDYCHERGVVH 520
+ D + + E R F+Q +V AV YCH++ +VH
Sbjct: 140 VFDYLVAHGKMKEKEARSKFRQGCQAGQTIKVQVSFDLLSLMFTFIVSAVQYCHQKRIVH 199
Query: 521 RDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRP 700
RD+K ENLL+D +NIK++DFGF+ + V +TFCGS YA+PE+ +G Y
Sbjct: 200 RDLKAENLLLDADMNIKIADFGFSN-----EFTVGGKLDTFCGSPPYAAPELFQGKKYDG 254
Query: 701 QDSDVWSMG 727
+ DVWS+G
Sbjct: 255 PEVDVWSLG 263
>AY505124-1|AAS86442.1| 778|Homo sapiens protein kinase SAD-B
protein.
Length = 778
Score = 121 bits (291), Expect = 3e-27
Identities = 60/166 (36%), Positives = 99/166 (59%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
+VAIKI+++ + L K + REI ++K ++H ++++ E +Y+V+E+ G
Sbjct: 59 KVAIKIVNREKLSESVLMK-VEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGE 117
Query: 410 LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGF 589
L D + K + R++F+Q+V A+D+CH + HRD+K ENLL+D NI+++DFG
Sbjct: 118 LFDYLVKKGRLTPKEARKFFRQIVSALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGM 177
Query: 590 ARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
A + +L ET CGS YA PE++KG Y + +D+WS G
Sbjct: 178 ASLQVGD-----SLLETSCGSPHYACPEVIKGEKYDGRRADMWSCG 218
>AY458602-1|AAS10354.1| 778|Homo sapiens SAD1 kinase protein.
Length = 778
Score = 121 bits (291), Expect = 3e-27
Identities = 60/166 (36%), Positives = 99/166 (59%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
+VAIKI+++ + L K + REI ++K ++H ++++ E +Y+V+E+ G
Sbjct: 59 KVAIKIVNREKLSESVLMK-VEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGE 117
Query: 410 LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGF 589
L D + K + R++F+Q+V A+D+CH + HRD+K ENLL+D NI+++DFG
Sbjct: 118 LFDYLVKKGRLTPKEARKFFRQIVSALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGM 177
Query: 590 ARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
A + +L ET CGS YA PE++KG Y + +D+WS G
Sbjct: 178 ASLQVGD-----SLLETSCGSPHYACPEVIKGEKYDGRRADMWSCG 218
>AF479827-1|AAL87698.1| 778|Homo sapiens protein kinase-like
protein protein.
Length = 778
Score = 121 bits (291), Expect = 3e-27
Identities = 60/166 (36%), Positives = 99/166 (59%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
+VAIKI+++ + L K + REI ++K ++H ++++ E +Y+V+E+ G
Sbjct: 59 KVAIKIVNREKLSESVLMK-VEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGE 117
Query: 410 LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGF 589
L D + K + R++F+Q+V A+D+CH + HRD+K ENLL+D NI+++DFG
Sbjct: 118 LFDYLVKKGRLTPKEARKFFRQIVSALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGM 177
Query: 590 ARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
A + +L ET CGS YA PE++KG Y + +D+WS G
Sbjct: 178 ASLQVGD-----SLLETSCGSPHYACPEVIKGEKYDGRRADMWSCG 218
>AF479826-1|AAL87697.1| 794|Homo sapiens putative serine/threonine
protein kinase protein.
Length = 794
Score = 121 bits (291), Expect = 3e-27
Identities = 60/166 (36%), Positives = 99/166 (59%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
+VAIKI+++ + L K + REI ++K ++H ++++ E +Y+V+E+ G
Sbjct: 75 KVAIKIVNREKLSESVLMK-VEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGE 133
Query: 410 LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGF 589
L D + K + R++F+Q+V A+D+CH + HRD+K ENLL+D NI+++DFG
Sbjct: 134 LFDYLVKKGRLTPKEARKFFRQIVSALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGM 193
Query: 590 ARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
A + +L ET CGS YA PE++KG Y + +D+WS G
Sbjct: 194 ASLQVGD-----SLLETSCGSPHYACPEVIKGEKYDGRRADMWSCG 234
>AF059681-1|AAC77369.1| 275|Homo sapiens serine/threonine kinase 13
protein.
Length = 275
Score = 117 bits (281), Expect = 5e-26
Identities = 59/173 (34%), Positives = 101/173 (58%)
Frame = +2
Query: 233 VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSL 412
VA+K++ K Q + L+ L REIE+ L+H N++R RVY+++EYA G L
Sbjct: 35 VALKVLFKSQIEKEGLEHQLRREIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGEL 94
Query: 413 LDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 592
++K + +DE R +++ +A+ YCH++ V+HRDIK ENLL+ +K++DFG++
Sbjct: 95 YKELQKSEKLDEQRTATIIEEVADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWS 154
Query: 593 RGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGSSIICHRL 751
P+ +T CG+ Y PE+++G Y + D+W +G ++C+ L
Sbjct: 155 VHTPLPER------KTMCGTLDYLPPEMIEGRTY-DEKVDLWCIG--VLCYEL 198
>BC012622-1|AAH12622.1| 207|Homo sapiens PRKAA1 protein protein.
Length = 207
Score = 116 bits (280), Expect = 7e-26
Identities = 59/152 (38%), Positives = 92/152 (60%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
+VA+KI+++ + + + REI+ +K +H ++I+ Q I T +++VMEY G
Sbjct: 43 KVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGE 102
Query: 410 LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGF 589
L D I K+ +DE RR F+Q++ VDYCH VVHRD+K EN+L+D +N K++DFG
Sbjct: 103 LFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGL 162
Query: 590 ARGHMKPKNGVFALSETFCGSYAYASPEILKG 685
+ +G F T CGS YA+PE++ G
Sbjct: 163 SN---MMSDGEFL--RTSCGSPNYAAPEVISG 189
>BC075064-1|AAH75064.2| 275|Homo sapiens AURKC protein protein.
Length = 275
Score = 115 bits (277), Expect = 2e-25
Identities = 60/173 (34%), Positives = 100/173 (57%)
Frame = +2
Query: 233 VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSL 412
VA+K++ K Q + L+ L REIE+ L+H N++R RVY+++EYA G L
Sbjct: 35 VALKVLFKSQIEKEGLEHQLRREIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGEL 94
Query: 413 LDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 592
++K + +DE R ++L +A+ YCH++ V+HRDIK ENLL+ +K++DFG++
Sbjct: 95 YKELQKSEKLDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWS 154
Query: 593 RGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGSSIICHRL 751
H +T CG+ Y PE+++G Y + D+W +G ++C+ L
Sbjct: 155 -VHTPSLR-----RKTMCGTLDYLPPEMIEGRTY-DEKVDLWCIG--VLCYEL 198
>AY714054-1|AAU04399.1| 306|Homo sapiens aurora-C protein.
Length = 306
Score = 115 bits (277), Expect = 2e-25
Identities = 60/173 (34%), Positives = 100/173 (57%)
Frame = +2
Query: 233 VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSL 412
VA+K++ K Q + L+ L REIE+ L+H N++R RVY+++EYA G L
Sbjct: 66 VALKVLFKSQIEKEGLEHQLRREIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGEL 125
Query: 413 LDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 592
++K + +DE R ++L +A+ YCH++ V+HRDIK ENLL+ +K++DFG++
Sbjct: 126 YKELQKSEKLDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWS 185
Query: 593 RGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGSSIICHRL 751
H +T CG+ Y PE+++G Y + D+W +G ++C+ L
Sbjct: 186 -VHTPSLR-----RKTMCGTLDYLPPEMIEGRTY-DEKVDLWCIG--VLCYEL 229
>AY661554-1|AAT64422.1| 290|Homo sapiens aurora/Ipl1-related kinase
3 transcript variant 1 protein.
Length = 290
Score = 115 bits (277), Expect = 2e-25
Identities = 60/173 (34%), Positives = 100/173 (57%)
Frame = +2
Query: 233 VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSL 412
VA+K++ K Q + L+ L REIE+ L+H N++R RVY+++EYA G L
Sbjct: 50 VALKVLFKSQIEKEGLEHQLRREIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGEL 109
Query: 413 LDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 592
++K + +DE R ++L +A+ YCH++ V+HRDIK ENLL+ +K++DFG++
Sbjct: 110 YKELQKSEKLDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWS 169
Query: 593 RGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGSSIICHRL 751
H +T CG+ Y PE+++G Y + D+W +G ++C+ L
Sbjct: 170 -VHTPSLR-----RKTMCGTLDYLPPEMIEGRTY-DEKVDLWCIG--VLCYEL 213
>AF054621-1|AAC25955.1| 309|Homo sapiens serine/threonine kinase
AIE2 protein.
Length = 309
Score = 115 bits (277), Expect = 2e-25
Identities = 60/173 (34%), Positives = 100/173 (57%)
Frame = +2
Query: 233 VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSL 412
VA+K++ K Q + L+ L REIE+ L+H N++R RVY+++EYA G L
Sbjct: 69 VALKVLFKSQIEKEGLEHQLRREIEIQAHLQHPNILRLYNHFHDARRVYLILEYAPRGEL 128
Query: 413 LDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 592
++K + +DE R ++L +A+ YCH++ V+HRDIK ENLL+ +K++DFG++
Sbjct: 129 YKELQKSEKLDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWS 188
Query: 593 RGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGSSIICHRL 751
H +T CG+ Y PE+++G Y + D+W +G ++C+ L
Sbjct: 189 -VHTPSLR-----RKTMCGTLDYLPPEMIEGRTY-DEKVDLWCIG--VLCYEL 232
>AB017332-1|BAA76292.1| 309|Homo sapiens Aurora/Ipl1-related kinase
3 protein.
Length = 309
Score = 115 bits (277), Expect = 2e-25
Identities = 60/173 (34%), Positives = 100/173 (57%)
Frame = +2
Query: 233 VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSL 412
VA+K++ K Q + L+ L REIE+ L+H N++R RVY+++EYA G L
Sbjct: 69 VALKVLFKSQIEKEGLEHQLRREIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGEL 128
Query: 413 LDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 592
++K + +DE R ++L +A+ YCH++ V+HRDIK ENLL+ +K++DFG++
Sbjct: 129 YKELQKSEKLDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWS 188
Query: 593 RGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGSSIICHRL 751
H +T CG+ Y PE+++G Y + D+W +G ++C+ L
Sbjct: 189 -VHTPSLR-----RKTMCGTLDYLPPEMIEGRTY-DEKVDLWCIG--VLCYEL 232
>AB058714-1|BAB47440.1| 715|Homo sapiens KIAA1811 protein protein.
Length = 715
Score = 113 bits (273), Expect = 5e-25
Identities = 53/144 (36%), Positives = 86/144 (59%)
Frame = +2
Query: 296 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQ 475
REI ++K ++H ++++ E +Y+V+E+ G L D + K + R++F+Q
Sbjct: 17 REIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQ 76
Query: 476 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 655
+V A+D+CH + HRD+K ENLL+D NI+++DFG A + +L ET CGS
Sbjct: 77 IVSALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGMASLQVGD-----SLLETSCGSP 131
Query: 656 AYASPEILKGVPYRPQDSDVWSMG 727
YA PE++KG Y + +D+WS G
Sbjct: 132 HYACPEVIKGEKYDGRRADMWSCG 155
>D43636-1|BAA07744.2| 766|Homo sapiens KIAA0096 protein.
Length = 766
Score = 113 bits (271), Expect = 9e-25
Identities = 60/169 (35%), Positives = 100/169 (59%), Gaps = 3/169 (1%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
+VA+K+I K + L +E+ +K ++H N++R + I+T ++Y+++E + G
Sbjct: 42 KVAVKVIDKTKLD-TLATGHLFQEVRCMKLVQHPNIVRLYEVIDTQTKLYLILELGDGGD 100
Query: 410 LLDIIRK-DQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLM--DHGLNIKLSD 580
+ D I K ++ ++E +++F Q+V A+ YCH+ VVHRD+K EN++ GL +KL+D
Sbjct: 101 MFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHKLHVVHRDLKPENVVFFEKQGL-VKLTD 159
Query: 581 FGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
FGF+ K T CGS AY++PEIL G Y D+WS+G
Sbjct: 160 FGFSNKFQPGKK-----LTTSCGSLAYSAPEILLGDEYDAPAVDIWSLG 203
>BC071567-1|AAH71567.1| 765|Homo sapiens SNRK protein protein.
Length = 765
Score = 113 bits (271), Expect = 9e-25
Identities = 60/169 (35%), Positives = 100/169 (59%), Gaps = 3/169 (1%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
+VA+K+I K + L +E+ +K ++H N++R + I+T ++Y+++E + G
Sbjct: 41 KVAVKVIDKTKLD-TLATGHLFQEVRCMKLVQHPNIVRLYEVIDTQTKLYLILELGDGGD 99
Query: 410 LLDIIRK-DQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLM--DHGLNIKLSD 580
+ D I K ++ ++E +++F Q+V A+ YCH+ VVHRD+K EN++ GL +KL+D
Sbjct: 100 MFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHKLHVVHRDLKPENVVFFEKQGL-VKLTD 158
Query: 581 FGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
FGF+ K T CGS AY++PEIL G Y D+WS+G
Sbjct: 159 FGFSNKFQPGKK-----LTTSCGSLAYSAPEILLGDEYDAPAVDIWSLG 202
>AK000231-1|BAA91023.1| 244|Homo sapiens protein ( Homo sapiens
cDNA FLJ20224 fis, clone COLF5039. ).
Length = 244
Score = 113 bits (271), Expect = 9e-25
Identities = 60/169 (35%), Positives = 100/169 (59%), Gaps = 3/169 (1%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
+VA+K+I K + L +E+ +K ++H N++R + I+T ++Y+++E + G
Sbjct: 41 KVAVKVIDKTKLD-TLATGHLFQEVRCMKLVQHPNIVRLYEVIDTQTKLYLILELGDGGD 99
Query: 410 LLDIIRK-DQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLM--DHGLNIKLSD 580
+ D I K ++ ++E +++F Q+V A+ YCH+ VVHRD+K EN++ GL +KL+D
Sbjct: 100 MFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHKLHVVHRDLKPENVVFFEKQGL-VKLTD 158
Query: 581 FGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
FGF+ K T CGS AY++PEIL G Y D+WS+G
Sbjct: 159 FGFSNKFQPGKK-----LTTSCGSLAYSAPEILLGDEYDAPAVDIWSLG 202
>BC048980-1|AAH48980.1| 574|Homo sapiens protein kinase,
AMP-activated, alpha 1 catalytic subunit protein.
Length = 574
Score = 112 bits (270), Expect = 1e-24
Identities = 64/181 (35%), Positives = 100/181 (55%), Gaps = 15/181 (8%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
+VA+KI+++ + + + REI+ +K +H ++I+ Q I T +++VMEY G
Sbjct: 52 KVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGE 111
Query: 410 LLDIIRKD---------------QHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 544
L D I K+ + +DE RR F+Q++ VDYCH VVHRD+K EN+
Sbjct: 112 LFDYICKNGRKSDVPGVVKTGSTKELDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENV 171
Query: 545 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 724
L+D +N K++DFG + +G F T CGS YA+PE++ G Y + D+WS
Sbjct: 172 LLDAHMNAKIADFGLSN---MMSDGEFL--RTSCGSPNYAAPEVISGRLYAGPEVDIWSS 226
Query: 725 G 727
G
Sbjct: 227 G 227
>BC031231-1|AAH31231.1| 514|Homo sapiens serine/threonine kinase 33
protein.
Length = 514
Score = 112 bits (269), Expect = 2e-24
Identities = 66/204 (32%), Positives = 112/204 (54%), Gaps = 10/204 (4%)
Frame = +2
Query: 146 DVRTHDNVLGEMSAEPTATVASSDRHN-CQVAIKIISKFQAPGDYLKKFLPREIEVVKGL 322
++ T +LG+ S + ++D+ + AIK ++K +A G K L RE+ ++K +
Sbjct: 114 EIYTFGRILGKGSFG--IVIEATDKETETKWAIKKVNKEKA-GSSAVKLLEREVNILKSV 170
Query: 323 KHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCH 502
KHE++I Q ET ++Y+VME E+G L +I+ + H E R + L A+ Y H
Sbjct: 171 KHEHIIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLH 230
Query: 503 ERGVVHRDIKCENLLM---------DHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 655
+VHRD+K EN+++ + LNIK++DFG A +K ++ A+ + CG+
Sbjct: 231 NNDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLA---VKKQSRSEAMLQATCGTP 287
Query: 656 AYASPEILKGVPYRPQDSDVWSMG 727
Y +PE++ Y Q D+WS+G
Sbjct: 288 IYMAPEVISAHDY-SQQCDIWSIG 310
>AK093251-1|BAC04109.1| 514|Homo sapiens protein ( Homo sapiens
cDNA FLJ35932 fis, clone TESTI2011286, weakly similar to
MYOSIN LIGHT CHAIN KINASE (EC 2.7.1.117). ).
Length = 514
Score = 112 bits (269), Expect = 2e-24
Identities = 66/204 (32%), Positives = 112/204 (54%), Gaps = 10/204 (4%)
Frame = +2
Query: 146 DVRTHDNVLGEMSAEPTATVASSDRHN-CQVAIKIISKFQAPGDYLKKFLPREIEVVKGL 322
++ T +LG+ S + ++D+ + AIK ++K +A G K L RE+ ++K +
Sbjct: 114 EIYTFGRILGKGSFG--IVIEATDKETETKWAIKKVNKEKA-GSSAVKLLEREVNILKSV 170
Query: 323 KHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCH 502
KHE++I Q ET ++Y+VME E+G L +I+ + H E R + L A+ Y H
Sbjct: 171 KHEHIIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLH 230
Query: 503 ERGVVHRDIKCENLLM---------DHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 655
+VHRD+K EN+++ + LNIK++DFG A +K ++ A+ + CG+
Sbjct: 231 NNDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLA---VKKQSRSEAMLQATCGTP 287
Query: 656 AYASPEILKGVPYRPQDSDVWSMG 727
Y +PE++ Y Q D+WS+G
Sbjct: 288 IYMAPEVISAHDY-SQQCDIWSIG 310
>AJ303380-1|CAC29064.1| 514|Homo sapiens serine/threonine kinase 33
protein.
Length = 514
Score = 112 bits (269), Expect = 2e-24
Identities = 66/204 (32%), Positives = 112/204 (54%), Gaps = 10/204 (4%)
Frame = +2
Query: 146 DVRTHDNVLGEMSAEPTATVASSDRHN-CQVAIKIISKFQAPGDYLKKFLPREIEVVKGL 322
++ T +LG+ S + ++D+ + AIK ++K +A G K L RE+ ++K +
Sbjct: 114 EIYTFGRILGKGSFG--IVIEATDKETETKWAIKKVNKEKA-GSSAVKLLEREVNILKSV 170
Query: 323 KHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCH 502
KHE++I Q ET ++Y+VME E+G L +I+ + H E R + L A+ Y H
Sbjct: 171 KHEHIIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLH 230
Query: 503 ERGVVHRDIKCENLLM---------DHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 655
+VHRD+K EN+++ + LNIK++DFG A +K ++ A+ + CG+
Sbjct: 231 NNDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLA---VKKQSRSEAMLQATCGTP 287
Query: 656 AYASPEILKGVPYRPQDSDVWSMG 727
Y +PE++ Y Q D+WS+G
Sbjct: 288 IYMAPEVISAHDY-SQQCDIWSIG 310
>AF226044-1|AAF86944.1| 765|Homo sapiens HSNFRK protein.
Length = 765
Score = 112 bits (269), Expect = 2e-24
Identities = 60/169 (35%), Positives = 100/169 (59%), Gaps = 3/169 (1%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
+VA+K+I K + L +E+ +K ++H N++R + I+T ++Y+++E + G
Sbjct: 41 KVAVKVIDKTKLD-TLATGHLFQEVRCMKLVQHPNIVRLYEVIDTQTKLYLILELGDEGD 99
Query: 410 LLDIIRK-DQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLM--DHGLNIKLSD 580
+ D I K ++ ++E +++F Q+V A+ YCH+ VVHRD+K EN++ GL +KL+D
Sbjct: 100 MFDYIMKHEEGLNEDLPKKYFAQIVHAISYCHKLHVVHRDLKPENVVFFEKQGL-VKLTD 158
Query: 581 FGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
FGF+ K T CGS AY++PEIL G Y D+WS+G
Sbjct: 159 FGFSNKFQPGKK-----LTTSCGSLAYSAPEILLGDEYDAPAVDIWSLG 202
>BC036422-1|AAH36422.1| 436|Homo sapiens hypothetical protein
MGC42105 protein.
Length = 436
Score = 111 bits (267), Expect = 3e-24
Identities = 58/166 (34%), Positives = 92/166 (55%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
+VAIKI+ K + ++ L REI ++ L H N+IR + +ET ++++VMEYA G
Sbjct: 99 KVAIKILDKTKLD-QKTQRLLSREISSMEKLHHPNIIRLYEVVETLSKLHLVMEYAGGGE 157
Query: 410 LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGF 589
L I + + E + F Q+V AV + HE ++HRD+K EN+ +K+ DFGF
Sbjct: 158 LFGKISTEGKLSEPESKLIFSQIVSAVKHMHENQIIHRDLKAENVFYTSNTCVKVGDFGF 217
Query: 590 ARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
+ K + + TFCGS YA+PE+ + Y D+W++G
Sbjct: 218 STVSKKGE-----MLNTFCGSPPYAAPELFRDEHYIGIYVDIWALG 258
>BC121188-1|AAI21189.1| 185|Homo sapiens KIAA0999 protein protein.
Length = 185
Score = 109 bits (261), Expect = 1e-23
Identities = 54/116 (46%), Positives = 75/116 (64%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
+VAIKII K Q + LKK RE++++K L H ++IR Q +ET +Y+V EYA G
Sbjct: 55 KVAIKIIDKTQLDEENLKKIF-REVQIMKMLCHPHIIRLYQVMETERMIYLVTEYASGGE 113
Query: 410 LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLS 577
+ D + + E RR FKQ+V AV +CH R +VHRD+K ENLL+D LNIK++
Sbjct: 114 IFDHLVAHGRMAEKEARRKFKQIVTAVYFCHCRNIVHRDLKAENLLLDANLNIKIA 169
>AJ006701-1|CAA07196.1| 603|Homo sapiens putative serine/threonine
protein kinase protein.
Length = 603
Score = 107 bits (257), Expect = 4e-23
Identities = 48/136 (35%), Positives = 80/136 (58%)
Frame = +2
Query: 320 LKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYC 499
++H ++++ E +Y+V+E+ G L D + K + R++F+Q++ A+D+C
Sbjct: 2 IEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFC 61
Query: 500 HERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEIL 679
H + HRD+K ENLL+D NI+++DFG A + +L ET CGS YA PE++
Sbjct: 62 HSHSICHRDLKPENLLLDEKNNIRIADFGMASLQVGD-----SLLETSCGSPHYACPEVI 116
Query: 680 KGVPYRPQDSDVWSMG 727
+G Y + +DVWS G
Sbjct: 117 RGEKYDGRKADVWSCG 132
>BC026158-1|AAH26158.1| 1315|Homo sapiens serine/threonine kinase
36, fused homolog (Drosophila) protein.
Length = 1315
Score = 107 bits (256), Expect = 6e-23
Identities = 63/165 (38%), Positives = 93/165 (56%)
Frame = +2
Query: 233 VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSL 412
VA+K I K L+ L REIE+++GL+H N++ L + ET V +V +YAE G L
Sbjct: 30 VALKFIPKLGRSEKELRN-LQREIEIMRGLRHPNIVHMLDSFETDKEVVVVTDYAE-GEL 87
Query: 413 LDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 592
I+ D + E + + QLV A+ Y H ++HRD+K +N+L+ G IKL DFGFA
Sbjct: 88 FQILEDDGKLPEDQVQAIAAQLVSALYYLHSHRILHRDMKPQNILLAKGGGIKLCDFGFA 147
Query: 593 RGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
R M V + G+ Y SPE+++ PY +D+WS+G
Sbjct: 148 RA-MSTNTMVLT---SIKGTPLYMSPELVEERPY-DHTADLWSVG 187
>AF200815-1|AAF97028.1| 1315|Homo sapiens FUSED serine/threonine
kinase protein.
Length = 1315
Score = 107 bits (256), Expect = 6e-23
Identities = 63/165 (38%), Positives = 93/165 (56%)
Frame = +2
Query: 233 VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSL 412
VA+K I K L+ L REIE+++GL+H N++ L + ET V +V +YAE G L
Sbjct: 30 VALKFIPKLGRSEKELRN-LQREIEIMRGLRHPNIVHMLDSFETDKEVVVVTDYAE-GEL 87
Query: 413 LDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 592
I+ D + E + + QLV A+ Y H ++HRD+K +N+L+ G IKL DFGFA
Sbjct: 88 FQILEDDGKLPEDQVQAIAAQLVSALYYLHSHRILHRDMKPQNILLAKGGGIKLCDFGFA 147
Query: 593 RGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
R M V + G+ Y SPE+++ PY +D+WS+G
Sbjct: 148 RA-MSTNTMVLT---SIKGTPLYMSPELVEERPY-DHTADLWSVG 187
>AB033104-1|BAA86592.1| 1311|Homo sapiens KIAA1278 protein protein.
Length = 1311
Score = 107 bits (256), Expect = 6e-23
Identities = 63/165 (38%), Positives = 93/165 (56%)
Frame = +2
Query: 233 VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSL 412
VA+K I K L+ L REIE+++GL+H N++ L + ET V +V +YAE G L
Sbjct: 47 VALKFIPKLGRSEKELRN-LQREIEIMRGLRHPNIVHMLDSFETDKEVVVVTDYAE-GEL 104
Query: 413 LDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 592
I+ D + E + + QLV A+ Y H ++HRD+K +N+L+ G IKL DFGFA
Sbjct: 105 FQILEDDGKLPEDQVQAIAAQLVSALYYLHSHRILHRDMKPQNILLAKGGGIKLCDFGFA 164
Query: 593 RGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
R M V + G+ Y SPE+++ PY +D+WS+G
Sbjct: 165 RA-MSTNTMVLT---SIKGTPLYMSPELVEERPY-DHTADLWSVG 204
>BC017575-1|AAH17575.1| 476|Homo sapiens CHK1 checkpoint homolog
(S. pombe) protein.
Length = 476
Score = 105 bits (252), Expect = 2e-22
Identities = 61/165 (36%), Positives = 88/165 (53%)
Frame = +2
Query: 233 VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSL 412
VA+KI+ +A + + +EI + K L HEN+++F + Y+ +EY G L
Sbjct: 35 VAVKIVDMKRAVD--CPENIKKEICINKMLNHENVVKFYGHRREGNIQYLFLEYCSGGEL 92
Query: 413 LDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 592
D I D + E +R+F QL+ V Y H G+ HRDIK ENLL+D N+K+SDFG A
Sbjct: 93 FDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGITHRDIKPENLLLDERDNLKISDFGLA 152
Query: 593 RGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
+ N L CG+ Y +PE+LK + + DVWS G
Sbjct: 153 T--VFRYNNRERLLNKMCGTLPYVAPELLKRREFHAEPVDVWSCG 195
>BC004202-1|AAH04202.1| 476|Homo sapiens CHEK1 protein protein.
Length = 476
Score = 105 bits (252), Expect = 2e-22
Identities = 61/165 (36%), Positives = 88/165 (53%)
Frame = +2
Query: 233 VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSL 412
VA+KI+ +A + + +EI + K L HEN+++F + Y+ +EY G L
Sbjct: 35 VAVKIVDMKRAVD--CPENIKKEICINKMLNHENVVKFYGHRREGNIQYLFLEYCSGGEL 92
Query: 413 LDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 592
D I D + E +R+F QL+ V Y H G+ HRDIK ENLL+D N+K+SDFG A
Sbjct: 93 FDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGITHRDIKPENLLLDERDNLKISDFGLA 152
Query: 593 RGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
+ N L CG+ Y +PE+LK + + DVWS G
Sbjct: 153 T--VFRYNNRERLLNKMCGTLPYVAPELLKRREFHAEPVDVWSCG 195
>AK027493-1|BAB55152.1| 638|Homo sapiens protein ( Homo sapiens
cDNA FLJ14587 fis, clone NT2RM4001758, moderately
similar to PUTATIVE SERINE/THREONINE-PROTEIN KINASE EMK
(EC 2.7.1.-). ).
Length = 638
Score = 105 bits (252), Expect = 2e-22
Identities = 50/114 (43%), Positives = 71/114 (62%)
Frame = +2
Query: 386 MEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLN 565
MEYA G + D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+D +N
Sbjct: 1 MEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDMN 60
Query: 566 IKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
IK++DFGF+ + V +TFCGS YA+PE+ +G Y + DVWS+G
Sbjct: 61 IKIADFGFSN-----EFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLG 109
>AF527555-1|AAM78553.1| 476|Homo sapiens CHK1 checkpoint homolog
(S. pombe) protein.
Length = 476
Score = 105 bits (252), Expect = 2e-22
Identities = 61/165 (36%), Positives = 88/165 (53%)
Frame = +2
Query: 233 VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSL 412
VA+KI+ +A + + +EI + K L HEN+++F + Y+ +EY G L
Sbjct: 35 VAVKIVDMKRAVD--CPENIKKEICINKMLNHENVVKFYGHRREGNIQYLFLEYCSGGEL 92
Query: 413 LDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 592
D I D + E +R+F QL+ V Y H G+ HRDIK ENLL+D N+K+SDFG A
Sbjct: 93 FDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGITHRDIKPENLLLDERDNLKISDFGLA 152
Query: 593 RGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
+ N L CG+ Y +PE+LK + + DVWS G
Sbjct: 153 T--VFRYNNRERLLNKMCGTLPYVAPELLKRREFHAEPVDVWSCG 195
>AF032874-1|AAB88852.1| 476|Homo sapiens protein kinase protein.
Length = 476
Score = 105 bits (252), Expect = 2e-22
Identities = 61/165 (36%), Positives = 88/165 (53%)
Frame = +2
Query: 233 VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSL 412
VA+KI+ +A + + +EI + K L HEN+++F + Y+ +EY G L
Sbjct: 35 VAVKIVDMKRAVD--CPENIKKEICINKMLNHENVVKFYGHRREGNIQYLFLEYCSGGEL 92
Query: 413 LDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 592
D I D + E +R+F QL+ V Y H G+ HRDIK ENLL+D N+K+SDFG A
Sbjct: 93 FDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGITHRDIKPENLLLDERDNLKISDFGLA 152
Query: 593 RGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
+ N L CG+ Y +PE+LK + + DVWS G
Sbjct: 153 T--VFRYNNRERLLNKMCGTLPYVAPELLKRREFHAEPVDVWSCG 195
>AF016582-1|AAC51736.1| 476|Homo sapiens Chk1 protein.
Length = 476
Score = 105 bits (252), Expect = 2e-22
Identities = 61/165 (36%), Positives = 88/165 (53%)
Frame = +2
Query: 233 VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSL 412
VA+KI+ +A + + +EI + K L HEN+++F + Y+ +EY G L
Sbjct: 35 VAVKIVDMKRAVD--CPENIKKEICINKMLNHENVVKFYGHRREGNIQYLFLEYCSGGEL 92
Query: 413 LDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 592
D I D + E +R+F QL+ V Y H G+ HRDIK ENLL+D N+K+SDFG A
Sbjct: 93 FDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGITHRDIKPENLLLDERDNLKISDFGLA 152
Query: 593 RGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
+ N L CG+ Y +PE+LK + + DVWS G
Sbjct: 153 T--VFRYNNRERLLNKMCGTLPYVAPELLKRREFHAEPVDVWSCG 195
>AB032387-1|BAA84577.1| 476|Homo sapiens checkpoint kinase protein.
Length = 476
Score = 105 bits (252), Expect = 2e-22
Identities = 61/165 (36%), Positives = 88/165 (53%)
Frame = +2
Query: 233 VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSL 412
VA+KI+ +A + + +EI + K L HEN+++F + Y+ +EY G L
Sbjct: 35 VAVKIVDMKRAVD--CPENIKKEICINKMLNHENVVKFYGHRREGNIQYLFLEYCSGGEL 92
Query: 413 LDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 592
D I D + E +R+F QL+ V Y H G+ HRDIK ENLL+D N+K+SDFG A
Sbjct: 93 FDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGITHRDIKPENLLLDERDNLKISDFGLA 152
Query: 593 RGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
+ N L CG+ Y +PE+LK + + DVWS G
Sbjct: 153 T--VFRYNNRERLLNKMCGTLPYVAPELLKRREFHAEPVDVWSCG 195
>Y15056-1|CAA75341.1| 556|Homo sapiens PkB kinase protein.
Length = 556
Score = 105 bits (251), Expect = 2e-22
Identities = 61/190 (32%), Positives = 107/190 (56%)
Frame = +2
Query: 167 VLGEMSAEPTATVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRF 346
+LGE S T +A + + AIKI+ K + ++ RE +V+ L H ++
Sbjct: 87 ILGEGSFS-TVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKL 145
Query: 347 LQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRD 526
+ ++Y + YA+NG LL IRK DET R + ++V A++Y H +G++HRD
Sbjct: 146 YFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRD 205
Query: 527 IKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQD 706
+K EN+L++ ++I+++DFG A+ + P++ A + +F G+ Y SPE+L +
Sbjct: 206 LKPENILLNEDMHIQITDFGTAK-VLSPESKQ-ARANSFVGTAQYVSPELLT-EKSACKS 262
Query: 707 SDVWSMGSSI 736
SD+W++G I
Sbjct: 263 SDLWALGCII 272
>CR536517-1|CAG38755.1| 556|Homo sapiens PDPK1 protein.
Length = 556
Score = 105 bits (251), Expect = 2e-22
Identities = 61/190 (32%), Positives = 107/190 (56%)
Frame = +2
Query: 167 VLGEMSAEPTATVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRF 346
+LGE S T +A + + AIKI+ K + ++ RE +V+ L H ++
Sbjct: 87 ILGEGSFS-TVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKL 145
Query: 347 LQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRD 526
+ ++Y + YA+NG LL IRK DET R + ++V A++Y H +G++HRD
Sbjct: 146 YFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRD 205
Query: 527 IKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQD 706
+K EN+L++ ++I+++DFG A+ + P++ A + +F G+ Y SPE+L +
Sbjct: 206 LKPENILLNEDMHIQITDFGTAK-VLSPESKQ-ARANSFVGTAQYVSPELLT-EKSACKS 262
Query: 707 SDVWSMGSSI 736
SD+W++G I
Sbjct: 263 SDLWALGCII 272
>BC012103-1|AAH12103.1| 556|Homo sapiens 3-phosphoinositide
dependent protein kinase-1 protein.
Length = 556
Score = 105 bits (251), Expect = 2e-22
Identities = 61/190 (32%), Positives = 107/190 (56%)
Frame = +2
Query: 167 VLGEMSAEPTATVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRF 346
+LGE S T +A + + AIKI+ K + ++ RE +V+ L H ++
Sbjct: 87 ILGEGSFS-TVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKL 145
Query: 347 LQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRD 526
+ ++Y + YA+NG LL IRK DET R + ++V A++Y H +G++HRD
Sbjct: 146 YFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRD 205
Query: 527 IKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQD 706
+K EN+L++ ++I+++DFG A+ + P++ A + +F G+ Y SPE+L +
Sbjct: 206 LKPENILLNEDMHIQITDFGTAK-VLSPESKQ-ARANSFVGTAQYVSPELLT-EKSACKS 262
Query: 707 SDVWSMGSSI 736
SD+W++G I
Sbjct: 263 SDLWALGCII 272
>AF017995-1|AAC51825.1| 556|Homo sapiens 3-phosphoinositide
dependent protein kinase-1 protein.
Length = 556
Score = 105 bits (251), Expect = 2e-22
Identities = 61/190 (32%), Positives = 107/190 (56%)
Frame = +2
Query: 167 VLGEMSAEPTATVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRF 346
+LGE S T +A + + AIKI+ K + ++ RE +V+ L H ++
Sbjct: 87 ILGEGSFS-TVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKL 145
Query: 347 LQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRD 526
+ ++Y + YA+NG LL IRK DET R + ++V A++Y H +G++HRD
Sbjct: 146 YFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRD 205
Query: 527 IKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQD 706
+K EN+L++ ++I+++DFG A+ + P++ A + +F G+ Y SPE+L +
Sbjct: 206 LKPENILLNEDMHIQITDFGTAK-VLSPESKQ-ARANSFVGTAQYVSPELLT-EKSACKS 262
Query: 707 SDVWSMGSSI 736
SD+W++G I
Sbjct: 263 SDLWALGCII 272
>AC005591-1|AAC33797.1| 367|Homo sapiens PkB-like protein.
Length = 367
Score = 105 bits (251), Expect = 2e-22
Identities = 61/190 (32%), Positives = 107/190 (56%)
Frame = +2
Query: 167 VLGEMSAEPTATVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRF 346
+LGE S T +A + + AIKI+ K + ++ RE +V+ L H ++
Sbjct: 79 ILGEGSFS-TVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKL 137
Query: 347 LQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRD 526
+ ++Y + YA+NG LL IRK DET R + ++V A++Y H +G++HRD
Sbjct: 138 YFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRD 197
Query: 527 IKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQD 706
+K EN+L++ ++I+++DFG A+ + P++ A + +F G+ Y SPE+L +
Sbjct: 198 LKPENILLNEDMHIQITDFGTAK-VLSPESKQ-ARANSFVGTAQYVSPELLT-EKSACKS 254
Query: 707 SDVWSMGSSI 736
SD+W++G I
Sbjct: 255 SDLWALGCII 264
>AB209835-1|BAD93072.1| 492|Homo sapiens 3-phosphoinositide
dependent protein kinase-1 variant protein.
Length = 492
Score = 105 bits (251), Expect = 2e-22
Identities = 61/190 (32%), Positives = 107/190 (56%)
Frame = +2
Query: 167 VLGEMSAEPTATVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRF 346
+LGE S T +A + + AIKI+ K + ++ RE +V+ L H ++
Sbjct: 125 ILGEGSFS-TVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKL 183
Query: 347 LQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRD 526
+ ++Y + YA+NG LL IRK DET R + ++V A++Y H +G++HRD
Sbjct: 184 YFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRD 243
Query: 527 IKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQD 706
+K EN+L++ ++I+++DFG A+ + P++ A + +F G+ Y SPE+L +
Sbjct: 244 LKPENILLNEDMHIQITDFGTAK-VLSPESKQ-ARANSFVGTAQYVSPELLT-EKSACKS 300
Query: 707 SDVWSMGSSI 736
SD+W++G I
Sbjct: 301 SDLWALGCII 310
>Z92542-3|CAI42485.1| 1030|Homo sapiens cyclin-dependent kinase-like
5 protein.
Length = 1030
Score = 104 bits (249), Expect = 4e-22
Identities = 57/172 (33%), Positives = 93/172 (54%), Gaps = 2/172 (1%)
Frame = +2
Query: 218 RHNCQVAIKIISKFQ--APGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVME 391
RH I I KF+ + +K+ RE+++++ LK EN++ +A ++Y+V E
Sbjct: 31 RHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTLKQENIVELKEAFRRRGKLYLVFE 90
Query: 392 YAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIK 571
Y E L + + + + + QL++A+ +CH+ +VHRDIK ENLL+ H +K
Sbjct: 91 YVEKNMLELLEEMPNGVPPEKVKSYIYQLIKAIHWCHKNDIVHRDIKPENLLISHNDVLK 150
Query: 572 LSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
L DFGFAR + N + + + Y SPE+L G PY + D+WS+G
Sbjct: 151 LCDFGFARNLSEGNNANYT---EYVATRWYRSPELLLGAPY-GKSVDMWSVG 198
>Y15057-1|CAA75342.1| 1030|Homo sapiens STK9 protein protein.
Length = 1030
Score = 104 bits (249), Expect = 4e-22
Identities = 57/172 (33%), Positives = 93/172 (54%), Gaps = 2/172 (1%)
Frame = +2
Query: 218 RHNCQVAIKIISKFQ--APGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVME 391
RH I I KF+ + +K+ RE+++++ LK EN++ +A ++Y+V E
Sbjct: 31 RHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTLKQENIVELKEAFRRRGKLYLVFE 90
Query: 392 YAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIK 571
Y E L + + + + + QL++A+ +CH+ +VHRDIK ENLL+ H +K
Sbjct: 91 YVEKNMLELLEEMPNGVPPEKVKSYIYQLIKAIHWCHKNDIVHRDIKPENLLISHNDVLK 150
Query: 572 LSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
L DFGFAR + N + + + Y SPE+L G PY + D+WS+G
Sbjct: 151 LCDFGFARNLSEGNNANYT---EYVATRWYRSPELLLGAPY-GKSVDMWSVG 198
>AY217744-1|AAO64440.1| 1030|Homo sapiens serine/threonine kinase 9
protein.
Length = 1030
Score = 104 bits (249), Expect = 4e-22
Identities = 57/172 (33%), Positives = 93/172 (54%), Gaps = 2/172 (1%)
Frame = +2
Query: 218 RHNCQVAIKIISKFQ--APGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVME 391
RH I I KF+ + +K+ RE+++++ LK EN++ +A ++Y+V E
Sbjct: 31 RHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTLKQENIVELKEAFRRRGKLYLVFE 90
Query: 392 YAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIK 571
Y E L + + + + + QL++A+ +CH+ +VHRDIK ENLL+ H +K
Sbjct: 91 YVEKNMLELLEEMPNGVPPEKVKSYIYQLIKAIHWCHKNDIVHRDIKPENLLISHNDVLK 150
Query: 572 LSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
L DFGFAR + N + + + Y SPE+L G PY + D+WS+G
Sbjct: 151 LCDFGFARNLSEGNNANYT---EYVATRWYRSPELLLGAPY-GKSVDMWSVG 198
>AL109798-1|CAI41159.1| 1030|Homo sapiens cyclin-dependent
kinase-like 5 protein.
Length = 1030
Score = 104 bits (249), Expect = 4e-22
Identities = 57/172 (33%), Positives = 93/172 (54%), Gaps = 2/172 (1%)
Frame = +2
Query: 218 RHNCQVAIKIISKFQ--APGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVME 391
RH I I KF+ + +K+ RE+++++ LK EN++ +A ++Y+V E
Sbjct: 31 RHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTLKQENIVELKEAFRRRGKLYLVFE 90
Query: 392 YAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIK 571
Y E L + + + + + QL++A+ +CH+ +VHRDIK ENLL+ H +K
Sbjct: 91 YVEKNMLELLEEMPNGVPPEKVKSYIYQLIKAIHWCHKNDIVHRDIKPENLLISHNDVLK 150
Query: 572 LSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
L DFGFAR + N + + + Y SPE+L G PY + D+WS+G
Sbjct: 151 LCDFGFARNLSEGNNANYT---EYVATRWYRSPELLLGAPY-GKSVDMWSVG 198
>AF045458-1|AAC32326.1| 1050|Homo sapiens serine/threonine kinase
ULK1 protein.
Length = 1050
Score = 104 bits (249), Expect = 4e-22
Identities = 56/183 (30%), Positives = 104/183 (56%), Gaps = 9/183 (4%)
Frame = +2
Query: 215 DRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEY 394
++H+ +VA+K I+K + L +EI+++K LKHEN++ E + VY+VMEY
Sbjct: 37 EKHDLEVAVKCINKKNLAKS--QTLLGKEIKILKELKHENIVALYDFQEMANSVYLVMEY 94
Query: 395 AENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD------- 553
G L D + + + E R + +Q+ A+ H +G++HRD+K +N+L+
Sbjct: 95 CNGGDLADYLHAMRTLSEDTIRLFLQQIAGAMRLLHSKGIIHRDLKPQNILLSNPAGRRA 154
Query: 554 --HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
+ + +K++DFGFAR +++ ++ T CGS Y +PE++ Y + +D+WS+G
Sbjct: 155 NPNSIRVKIADFGFAR-YLQSN----MMAATLCGSPMYMAPEVIMSQHYDGK-ADLWSIG 208
Query: 728 SSI 736
+ +
Sbjct: 209 TIV 211
>AB018265-1|BAA34442.2| 1066|Homo sapiens KIAA0722 protein protein.
Length = 1066
Score = 104 bits (249), Expect = 4e-22
Identities = 56/183 (30%), Positives = 104/183 (56%), Gaps = 9/183 (4%)
Frame = +2
Query: 215 DRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEY 394
++H+ +VA+K I+K + L +EI+++K LKHEN++ E + VY+VMEY
Sbjct: 53 EKHDLEVAVKCINKKNLAKS--QTLLGKEIKILKELKHENIVALYDFQEMANSVYLVMEY 110
Query: 395 AENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD------- 553
G L D + + + E R + +Q+ A+ H +G++HRD+K +N+L+
Sbjct: 111 CNGGDLADYLHAMRTLSEDTIRLFLQQIAGAMRLLHSKGIIHRDLKPQNILLSNPAGRRA 170
Query: 554 --HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
+ + +K++DFGFAR +++ ++ T CGS Y +PE++ Y + +D+WS+G
Sbjct: 171 NPNSIRVKIADFGFAR-YLQSN----MMAATLCGSPMYMAPEVIMSQHYDGK-ADLWSIG 224
Query: 728 SSI 736
+ +
Sbjct: 225 TIV 227
>BC027464-1|AAH27464.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 103 bits (248), Expect = 5e-22
Identities = 54/171 (31%), Positives = 95/171 (55%)
Frame = +2
Query: 233 VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSL 412
+A+K++ K Q ++ L RE+E+ L+H N++R RVY+++EYA G++
Sbjct: 159 LALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTV 218
Query: 413 LDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 592
++K DE R + +L A+ YCH + V+HRDIK ENLL+ +K++DFG++
Sbjct: 219 YRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS 278
Query: 593 RGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGSSIICH 745
+ + T CG+ Y PE+++G + D+WS+G ++C+
Sbjct: 279 ------VHAPSSRRTTLCGTLDYLPPEMIEG-RMHDEKVDLWSLG--VLCY 320
>BC006423-1|AAH06423.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 103 bits (248), Expect = 5e-22
Identities = 54/171 (31%), Positives = 95/171 (55%)
Frame = +2
Query: 233 VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSL 412
+A+K++ K Q ++ L RE+E+ L+H N++R RVY+++EYA G++
Sbjct: 159 LALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTV 218
Query: 413 LDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 592
++K DE R + +L A+ YCH + V+HRDIK ENLL+ +K++DFG++
Sbjct: 219 YRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS 278
Query: 593 RGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGSSIICH 745
+ + T CG+ Y PE+++G + D+WS+G ++C+
Sbjct: 279 ------VHAPSSRRTTLCGTLDYLPPEMIEG-RMHDEKVDLWSLG--VLCY 320
>BC002499-1|AAH02499.1| 403|Homo sapiens AURKA protein protein.
Length = 403
Score = 103 bits (248), Expect = 5e-22
Identities = 54/171 (31%), Positives = 95/171 (55%)
Frame = +2
Query: 233 VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSL 412
+A+K++ K Q ++ L RE+E+ L+H N++R RVY+++EYA G++
Sbjct: 159 LALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTV 218
Query: 413 LDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 592
++K DE R + +L A+ YCH + V+HRDIK ENLL+ +K++DFG++
Sbjct: 219 YRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS 278
Query: 593 RGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGSSIICH 745
+ + T CG+ Y PE+++G + D+WS+G ++C+
Sbjct: 279 ------VHAPSSRRTTLCGTLDYLPPEMIEG-RMHDEKVDLWSLG--VLCY 320
>BC001280-1|AAH01280.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 103 bits (248), Expect = 5e-22
Identities = 54/171 (31%), Positives = 95/171 (55%)
Frame = +2
Query: 233 VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSL 412
+A+K++ K Q ++ L RE+E+ L+H N++R RVY+++EYA G++
Sbjct: 159 LALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTV 218
Query: 413 LDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 592
++K DE R + +L A+ YCH + V+HRDIK ENLL+ +K++DFG++
Sbjct: 219 YRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS 278
Query: 593 RGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGSSIICH 745
+ + T CG+ Y PE+++G + D+WS+G ++C+
Sbjct: 279 ------VHAPSSRRTTLCGTLDYLPPEMIEG-RMHDEKVDLWSLG--VLCY 320
>AL121914-4|CAM45838.1| 347|Homo sapiens aurora kinase A protein.
Length = 347
Score = 103 bits (248), Expect = 5e-22
Identities = 54/171 (31%), Positives = 95/171 (55%)
Frame = +2
Query: 233 VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSL 412
+A+K++ K Q ++ L RE+E+ L+H N++R RVY+++EYA G++
Sbjct: 159 LALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTV 218
Query: 413 LDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 592
++K DE R + +L A+ YCH + V+HRDIK ENLL+ +K++DFG++
Sbjct: 219 YRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS 278
Query: 593 RGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGSSIICH 745
+ + T CG+ Y PE+++G + D+WS+G ++C+
Sbjct: 279 ------VHAPSSRRTTLCGTLDYLPPEMIEG-RMHDEKVDLWSLG--VLCY 320
>AL121914-3|CAC12717.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 103 bits (248), Expect = 5e-22
Identities = 54/171 (31%), Positives = 95/171 (55%)
Frame = +2
Query: 233 VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSL 412
+A+K++ K Q ++ L RE+E+ L+H N++R RVY+++EYA G++
Sbjct: 159 LALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTV 218
Query: 413 LDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 592
++K DE R + +L A+ YCH + V+HRDIK ENLL+ +K++DFG++
Sbjct: 219 YRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS 278
Query: 593 RGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGSSIICH 745
+ + T CG+ Y PE+++G + D+WS+G ++C+
Sbjct: 279 ------VHAPSSRRTTLCGTLDYLPPEMIEG-RMHDEKVDLWSLG--VLCY 320
>AK222581-1|BAD96301.1| 556|Homo sapiens 3-phosphoinositide
dependent protein kinase-1 variant protein.
Length = 556
Score = 103 bits (248), Expect = 5e-22
Identities = 61/190 (32%), Positives = 106/190 (55%)
Frame = +2
Query: 167 VLGEMSAEPTATVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRF 346
+LGE S T +A + + AIKI+ K + ++ RE +V+ L H ++
Sbjct: 87 ILGEGSFS-TVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKL 145
Query: 347 LQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRD 526
+ ++Y + YA+NG LL IRK DET R + ++V A +Y H +G++HRD
Sbjct: 146 YFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSASEYLHGKGIIHRD 205
Query: 527 IKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQD 706
+K EN+L++ ++I+++DFG A+ + P++ A + +F G+ Y SPE+L +
Sbjct: 206 LKPENILLNEDMHIQITDFGTAK-VLSPESKQ-ARANSFVGTAQYVSPELLT-EKSACKS 262
Query: 707 SDVWSMGSSI 736
SD+W++G I
Sbjct: 263 SDLWALGCII 272
>AK074578-1|BAC11070.1| 426|Homo sapiens protein ( Homo sapiens
cDNA FLJ90097 fis, clone HEMBA1005929, weakly similar to
H.sapiens mRNA for serine/threonine protein kinase EMK.
).
Length = 426
Score = 103 bits (248), Expect = 5e-22
Identities = 48/114 (42%), Positives = 71/114 (62%)
Frame = +2
Query: 386 MEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLN 565
MEYA G + D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+D N
Sbjct: 1 MEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEAN 60
Query: 566 IKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
IK++DFGF+ + + + +TFCGS YA+PE+ +G Y + D+WS+G
Sbjct: 61 IKIADFGFSN-----EFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLG 109
>AJ785968-1|CAH05056.1| 396|Homo sapiens PDPK2 protein protein.
Length = 396
Score = 103 bits (248), Expect = 5e-22
Identities = 61/190 (32%), Positives = 106/190 (55%)
Frame = +2
Query: 167 VLGEMSAEPTATVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRF 346
+LGE S T +A + + AIKI+ K + ++ RE +V+ L H ++
Sbjct: 60 ILGEGSFS-TVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKL 118
Query: 347 LQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRD 526
+ ++Y + YA+NG LL IRK DET R + ++V A++Y H +G++HRD
Sbjct: 119 YFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRD 178
Query: 527 IKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQD 706
+K EN+L++ + I+++DFG A+ + P++ A + +F G+ Y SPE+L +
Sbjct: 179 LKPENILLNEDMYIQITDFGTAK-VLSPESKQ-ARANSFVGTAQYVSPELLT-EKSACKS 235
Query: 707 SDVWSMGSSI 736
SD+W++G I
Sbjct: 236 SDLWALGCII 245
>AF195947-1|AAF29508.1| 403|Homo sapiens STK15 serine/threonine
kinase protein.
Length = 403
Score = 103 bits (248), Expect = 5e-22
Identities = 54/171 (31%), Positives = 95/171 (55%)
Frame = +2
Query: 233 VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSL 412
+A+K++ K Q ++ L RE+E+ L+H N++R RVY+++EYA G++
Sbjct: 159 LALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTV 218
Query: 413 LDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 592
++K DE R + +L A+ YCH + V+HRDIK ENLL+ +K++DFG++
Sbjct: 219 YRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS 278
Query: 593 RGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGSSIICH 745
+ + T CG+ Y PE+++G + D+WS+G ++C+
Sbjct: 279 ------VHAPSSRRTTLCGTLDYLPPEMIEG-RMHDEKVDLWSLG--VLCY 320
>AF011468-1|AAC63902.1| 403|Homo sapiens serine/threonine kinase
protein.
Length = 403
Score = 103 bits (248), Expect = 5e-22
Identities = 54/171 (31%), Positives = 95/171 (55%)
Frame = +2
Query: 233 VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSL 412
+A+K++ K Q ++ L RE+E+ L+H N++R RVY+++EYA G++
Sbjct: 159 LALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTV 218
Query: 413 LDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 592
++K DE R + +L A+ YCH + V+HRDIK ENLL+ +K++DFG++
Sbjct: 219 YRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS 278
Query: 593 RGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGSSIICH 745
+ + T CG+ Y PE+++G + D+WS+G ++C+
Sbjct: 279 ------VHAPSSRRTTLCGTLDYLPPEMIEG-RMHDEKVDLWSLG--VLCY 320
>AF008551-1|AAC12708.1| 403|Homo sapiens aurora-related kinase 1
protein.
Length = 403
Score = 103 bits (248), Expect = 5e-22
Identities = 54/171 (31%), Positives = 95/171 (55%)
Frame = +2
Query: 233 VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSL 412
+A+K++ K Q ++ L RE+E+ L+H N++R RVY+++EYA G++
Sbjct: 159 LALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTV 218
Query: 413 LDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 592
++K DE R + +L A+ YCH + V+HRDIK ENLL+ +K++DFG++
Sbjct: 219 YRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS 278
Query: 593 RGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGSSIICH 745
+ + T CG+ Y PE+++G + D+WS+G ++C+
Sbjct: 279 ------VHAPSSRRTTLCGTLDYLPPEMIEG-RMHDEKVDLWSLG--VLCY 320
>BT019534-1|AAV38341.1| 344|Homo sapiens serine/threonine kinase 12
protein.
Length = 344
Score = 103 bits (247), Expect = 7e-22
Identities = 56/173 (32%), Positives = 96/173 (55%)
Frame = +2
Query: 233 VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSL 412
VA+K++ K Q + ++ L REIE+ L H N++R R+Y+++EYA G L
Sbjct: 103 VALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGEL 162
Query: 413 LDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 592
++K DE R ++L +A+ YCH + V+HRDIK ENLL+ +K++DFG++
Sbjct: 163 YKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWS 222
Query: 593 RGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGSSIICHRL 751
+ +T CG+ Y PE+++G + + D+W +G ++C+ L
Sbjct: 223 ------VHAPSLRRKTMCGTLDYLPPEMIEGRMHN-EKVDLWCIG--VLCYEL 266
>BC080581-1|AAH80581.1| 344|Homo sapiens aurora kinase B protein.
Length = 344
Score = 103 bits (247), Expect = 7e-22
Identities = 56/173 (32%), Positives = 96/173 (55%)
Frame = +2
Query: 233 VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSL 412
VA+K++ K Q + ++ L REIE+ L H N++R R+Y+++EYA G L
Sbjct: 103 VALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGEL 162
Query: 413 LDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 592
++K DE R ++L +A+ YCH + V+HRDIK ENLL+ +K++DFG++
Sbjct: 163 YKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWS 222
Query: 593 RGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGSSIICHRL 751
+ +T CG+ Y PE+++G + + D+W +G ++C+ L
Sbjct: 223 ------VHAPSLRRKTMCGTLDYLPPEMIEGRMHN-EKVDLWCIG--VLCYEL 266
>BC013300-1|AAH13300.2| 371|Homo sapiens AURKB protein protein.
Length = 371
Score = 103 bits (247), Expect = 7e-22
Identities = 56/173 (32%), Positives = 96/173 (55%)
Frame = +2
Query: 233 VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSL 412
VA+K++ K Q + ++ L REIE+ L H N++R R+Y+++EYA G L
Sbjct: 130 VALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGEL 189
Query: 413 LDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 592
++K DE R ++L +A+ YCH + V+HRDIK ENLL+ +K++DFG++
Sbjct: 190 YKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWS 249
Query: 593 RGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGSSIICHRL 751
+ +T CG+ Y PE+++G + + D+W +G ++C+ L
Sbjct: 250 ------VHAPSLRRKTMCGTLDYLPPEMIEGRMHN-EKVDLWCIG--VLCYEL 293
>BC009751-1|AAH09751.1| 344|Homo sapiens aurora kinase B protein.
Length = 344
Score = 103 bits (247), Expect = 7e-22
Identities = 56/173 (32%), Positives = 96/173 (55%)
Frame = +2
Query: 233 VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSL 412
VA+K++ K Q + ++ L REIE+ L H N++R R+Y+++EYA G L
Sbjct: 103 VALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGEL 162
Query: 413 LDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 592
++K DE R ++L +A+ YCH + V+HRDIK ENLL+ +K++DFG++
Sbjct: 163 YKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWS 222
Query: 593 RGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGSSIICHRL 751
+ +T CG+ Y PE+++G + + D+W +G ++C+ L
Sbjct: 223 ------VHAPSLRRKTMCGTLDYLPPEMIEGRMHN-EKVDLWCIG--VLCYEL 266
>BC000442-1|AAH00442.3| 344|Homo sapiens aurora kinase B protein.
Length = 344
Score = 103 bits (247), Expect = 7e-22
Identities = 56/173 (32%), Positives = 96/173 (55%)
Frame = +2
Query: 233 VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSL 412
VA+K++ K Q + ++ L REIE+ L H N++R R+Y+++EYA G L
Sbjct: 103 VALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGEL 162
Query: 413 LDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 592
++K DE R ++L +A+ YCH + V+HRDIK ENLL+ +K++DFG++
Sbjct: 163 YKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWS 222
Query: 593 RGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGSSIICHRL 751
+ +T CG+ Y PE+++G + + D+W +G ++C+ L
Sbjct: 223 ------VHAPSLRRKTMCGTLDYLPPEMIEGRMHN-EKVDLWCIG--VLCYEL 266
>AF008552-1|AAC12709.1| 344|Homo sapiens aurora-related kinase 2
protein.
Length = 344
Score = 103 bits (247), Expect = 7e-22
Identities = 56/173 (32%), Positives = 96/173 (55%)
Frame = +2
Query: 233 VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSL 412
VA+K++ K Q + ++ L REIE+ L H N++R R+Y+++EYA G L
Sbjct: 103 VALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGEL 162
Query: 413 LDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 592
++K DE R ++L +A+ YCH + V+HRDIK ENLL+ +K++DFG++
Sbjct: 163 YKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWS 222
Query: 593 RGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGSSIICHRL 751
+ +T CG+ Y PE+++G + + D+W +G ++C+ L
Sbjct: 223 ------VHAPSLRRKTMCGTLDYLPPEMIEGRMHN-EKVDLWCIG--VLCYEL 266
>AB011450-1|BAA32136.1| 344|Homo sapiens aurora and IPL1-like
midbody-associated protein kinase-1 protein.
Length = 344
Score = 103 bits (247), Expect = 7e-22
Identities = 56/173 (32%), Positives = 96/173 (55%)
Frame = +2
Query: 233 VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSL 412
VA+K++ K Q + ++ L REIE+ L H N++R R+Y+++EYA G L
Sbjct: 103 VALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGEL 162
Query: 413 LDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 592
++K DE R ++L +A+ YCH + V+HRDIK ENLL+ +K++DFG++
Sbjct: 163 YKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWS 222
Query: 593 RGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGSSIICHRL 751
+ +T CG+ Y PE+++G + + D+W +G ++C+ L
Sbjct: 223 ------VHAPSLRRKTMCGTLDYLPPEMIEGRMHN-EKVDLWCIG--VLCYEL 266
>D84212-1|BAA23592.1| 402|Homo sapiens aurora/IPL1-related kinase
protein.
Length = 402
Score = 103 bits (246), Expect = 9e-22
Identities = 53/171 (30%), Positives = 95/171 (55%)
Frame = +2
Query: 233 VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSL 412
+A+K++ K Q ++ L RE+E+ L+H N++R RVY+++EYA G++
Sbjct: 158 LALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTV 217
Query: 413 LDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 592
++K DE R + ++ A+ YCH + V+HRDIK ENLL+ +K++DFG++
Sbjct: 218 YRELQKLSKFDEQRTANLYNRIANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS 277
Query: 593 RGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGSSIICH 745
+ + T CG+ Y PE+++G + D+WS+G ++C+
Sbjct: 278 ------VHAPSSRRTTLCGTLDYLPPEMIEG-RMHDEKVDLWSLG--VLCY 319
>AB011446-1|BAA82709.1| 343|Homo sapiens Aik2 protein.
Length = 343
Score = 102 bits (245), Expect = 1e-21
Identities = 56/173 (32%), Positives = 95/173 (54%)
Frame = +2
Query: 233 VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSL 412
VA+K++ K Q + ++ L REIE+ L H N++R R+Y+++EYA G L
Sbjct: 103 VALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGEL 162
Query: 413 LDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 592
++K DE R ++L +A+ YCH + V+HRDIK ENLL+ +K++DFG++
Sbjct: 163 YKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWS 222
Query: 593 RGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGSSIICHRL 751
+ +T CG+ Y PE+++G + D+W +G ++C+ L
Sbjct: 223 ------VHATSLRRKTMCGTLDYLPPEMIEG-RIDNEKVDLWCIG--VLCYEL 266
>AF004022-1|AAB65786.1| 347|Homo sapiens protein kinase protein.
Length = 347
Score = 101 bits (241), Expect = 4e-21
Identities = 58/176 (32%), Positives = 97/176 (55%), Gaps = 3/176 (1%)
Frame = +2
Query: 233 VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSL 412
VA+K++ K Q + ++ L REIE+ L H N++R R+Y+++EYA G L
Sbjct: 103 VALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGML 162
Query: 413 LDIIRKDQHIDETRG---RRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDF 583
+ K DE R RR ++L +A+ YCH + V+HRDIK ENLL+ +K++DF
Sbjct: 163 YKELHKTCTFDEQRTATVRRIMEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADF 222
Query: 584 GFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGSSIICHRL 751
G++ + +T CG+ Y PE+++G + + D+W +G ++C+ L
Sbjct: 223 GWS------VHAPSLRRKTMCGTLDYLPPEMIEGRMHN-EKVDLWCIG--VLCYEL 269
>AL592406-2|CAH72462.1| 758|Homo sapiens MAP/microtubule
affinity-regulating kinase 1 protein.
Length = 758
Score = 100 bits (240), Expect = 5e-21
Identities = 49/127 (38%), Positives = 75/127 (59%)
Frame = +2
Query: 347 LQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRD 526
LQ + R+ ++ + G + D + + E R F+Q+V AV YCH++ +VHRD
Sbjct: 101 LQKLFREVRIMKILNHPNIGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRD 160
Query: 527 IKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQD 706
+K ENLL+D +NIK++DFGF+ + V +TFCGS YA+PE+ +G Y +
Sbjct: 161 LKAENLLLDGDMNIKIADFGFSN-----EFTVGNKLDTFCGSPPYAAPELFQGKKYDGPE 215
Query: 707 SDVWSMG 727
DVWS+G
Sbjct: 216 VDVWSLG 222
>AB040910-1|BAA96001.1| 870|Homo sapiens KIAA1477 protein protein.
Length = 870
Score = 100 bits (240), Expect = 5e-21
Identities = 49/127 (38%), Positives = 75/127 (59%)
Frame = +2
Query: 347 LQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRD 526
LQ + R+ ++ + G + D + + E R F+Q+V AV YCH++ +VHRD
Sbjct: 213 LQKLFREVRIMKILNHPNIGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRD 272
Query: 527 IKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQD 706
+K ENLL+D +NIK++DFGF+ + V +TFCGS YA+PE+ +G Y +
Sbjct: 273 LKAENLLLDGDMNIKIADFGFSN-----EFTVGNKLDTFCGSPPYAAPELFQGKKYDGPE 327
Query: 707 SDVWSMG 727
DVWS+G
Sbjct: 328 VDVWSLG 334
>BC034988-1|AAH34988.1| 1036|Homo sapiens ULK2 protein protein.
Length = 1036
Score = 99.5 bits (237), Expect = 1e-20
Identities = 57/178 (32%), Positives = 99/178 (55%), Gaps = 9/178 (5%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
+VAIK I+K + L +EI+++K L+HEN++ E + V++VMEY G
Sbjct: 35 EVAIKSINKKNLSKSQI--LLGKEIKILKELQHENIVALYDVQELPNSVFLVMEYCNGGD 92
Query: 410 LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDH---------GL 562
L D ++ + E R + Q+ A+ H +G++HRD+K +N+L+ + G+
Sbjct: 93 LADYLQAKGTLSEDTIRVFLHQIAAAMRILHSKGIIHRDLKPQNILLSYANRRKSSVSGI 152
Query: 563 NIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGSSI 736
IK++DFGFAR ++ ++ T CGS Y +PE++ Y + +D+WS+G+ I
Sbjct: 153 RIKIADFGFAR-YLHSN----MMAATLCGSPMYMAPEVIMSQHYDAK-ADLWSIGTVI 204
>AF015254-1|AAC98891.1| 347|Homo sapiens serine/threonine kinase
protein.
Length = 347
Score = 99.5 bits (237), Expect = 1e-20
Identities = 57/176 (32%), Positives = 97/176 (55%), Gaps = 3/176 (1%)
Frame = +2
Query: 233 VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSL 412
VA+K++ K Q + ++ L REIE+ L H N++R R+Y+++EYA G L
Sbjct: 103 VALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGML 162
Query: 413 LDIIRKDQHIDETRG---RRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDF 583
++K DE R R ++L +A+ YCH + V+HRDIK ENLL+ +K++DF
Sbjct: 163 YKELQKSCTFDEQRTATVRAVMEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADF 222
Query: 584 GFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGSSIICHRL 751
G++ + +T CG+ Y PE+++G + + D+W +G ++C+ L
Sbjct: 223 GWS------VHAPSLRRKTMCGTLDYLPPEMIEGRMHN-EKVDLWCIG--VLCYEL 269
>AB014523-1|BAA31598.2| 1100|Homo sapiens KIAA0623 protein protein.
Length = 1100
Score = 99.5 bits (237), Expect = 1e-20
Identities = 57/178 (32%), Positives = 99/178 (55%), Gaps = 9/178 (5%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
+VAIK I+K + L +EI+++K L+HEN++ E + V++VMEY G
Sbjct: 99 EVAIKSINKKNLSKSQI--LLGKEIKILKELQHENIVALYDVQELPNSVFLVMEYCNGGD 156
Query: 410 LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDH---------GL 562
L D ++ + E R + Q+ A+ H +G++HRD+K +N+L+ + G+
Sbjct: 157 LADYLQAKGTLSEDTIRVFLHQIAAAMRILHSKGIIHRDLKPQNILLSYANRRKSSVSGI 216
Query: 563 NIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGSSI 736
IK++DFGFAR ++ ++ T CGS Y +PE++ Y + +D+WS+G+ I
Sbjct: 217 RIKIADFGFAR-YLHSN----MMAATLCGSPMYMAPEVIMSQHYDAK-ADLWSIGTVI 268
>BC114491-1|AAI14492.1| 1189|Homo sapiens NEK1 protein protein.
Length = 1189
Score = 98.7 bits (235), Expect = 2e-20
Identities = 50/146 (34%), Positives = 81/146 (55%), Gaps = 2/146 (1%)
Frame = +2
Query: 296 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHI--DETRGRRWF 469
RE+ V+ +KH N++++ ++ E +YIVM+Y E G L I + + E + WF
Sbjct: 50 REVAVLANMKHPNIVQYRESFEENGSLYIVMDYCEGGDLFKRINAQKGVLFQEDQILDWF 109
Query: 470 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 649
Q+ A+ + H+R ++HRDIK +N+ + ++L DFG AR N L+ T G
Sbjct: 110 VQICLALKHVHDRKILHRDIKSQNIFLTKDGTVQLGDFGIAR----VLNSTVELARTCIG 165
Query: 650 SYAYASPEILKGVPYRPQDSDVWSMG 727
+ Y SPEI + PY SD+W++G
Sbjct: 166 TPYYLSPEICENKPYN-NKSDIWALG 190
>BC015147-1|AAH15147.1| 403|Homo sapiens Unknown (protein for
IMAGE:4063881) protein.
Length = 403
Score = 98.7 bits (235), Expect = 2e-20
Identities = 50/146 (34%), Positives = 81/146 (55%), Gaps = 2/146 (1%)
Frame = +2
Query: 296 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHI--DETRGRRWF 469
RE+ V+ +KH N++++ ++ E +YIVM+Y E G L I + + E + WF
Sbjct: 50 REVAVLANMKHPNIVQYRESFEENGSLYIVMDYCEGGDLFKRINAQKGVLFQEDQILDWF 109
Query: 470 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 649
Q+ A+ + H+R ++HRDIK +N+ + ++L DFG AR N L+ T G
Sbjct: 110 VQICLALKHVHDRKILHRDIKSQNIFLTKDGTVQLGDFGIAR----VLNSTVELARTCIG 165
Query: 650 SYAYASPEILKGVPYRPQDSDVWSMG 727
+ Y SPEI + PY SD+W++G
Sbjct: 166 TPYYLSPEICENKPYN-NKSDIWALG 190
>AB067488-1|BAB67794.1| 1265|Homo sapiens KIAA1901 protein protein.
Length = 1265
Score = 98.7 bits (235), Expect = 2e-20
Identities = 50/146 (34%), Positives = 81/146 (55%), Gaps = 2/146 (1%)
Frame = +2
Query: 296 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHI--DETRGRRWF 469
RE+ V+ +KH N++++ ++ E +YIVM+Y E G L I + + E + WF
Sbjct: 57 REVAVLANMKHPNIVQYRESFEENGSLYIVMDYCEGGDLFKRINAQKGVLFQEDQILDWF 116
Query: 470 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 649
Q+ A+ + H+R ++HRDIK +N+ + ++L DFG AR N L+ T G
Sbjct: 117 VQICLALKHVHDRKILHRDIKSQNIFLTKDGTVQLGDFGIAR----VLNSTVELARTCIG 172
Query: 650 SYAYASPEILKGVPYRPQDSDVWSMG 727
+ Y SPEI + PY SD+W++G
Sbjct: 173 TPYYLSPEICENKPYN-NKSDIWALG 197
>BC019916-1|AAH19916.2| 506|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 3 protein.
Length = 506
Score = 97.5 bits (232), Expect = 5e-20
Identities = 51/146 (34%), Positives = 81/146 (55%), Gaps = 2/146 (1%)
Frame = +2
Query: 296 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIR--KDQHIDETRGRRWF 469
+E ++ +KH N++ F ++ E +YIVMEY + G L+ I+ K + E WF
Sbjct: 49 KEAVLLAKMKHPNIVAFKESFEAEGHLYIVMEYCDGGDLMQKIKQQKGKLFPEDMILNWF 108
Query: 470 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 649
Q+ V++ H++ V+HRDIK +N+ + +KL DFG AR P A + T+ G
Sbjct: 109 TQMCLGVNHIHKKRVLHRDIKSKNIFLTQNGKVKLGDFGSARLLSNP----MAFACTYVG 164
Query: 650 SYAYASPEILKGVPYRPQDSDVWSMG 727
+ Y PEI + +PY SD+WS+G
Sbjct: 165 TPYYVPPEIWENLPYN-NKSDIWSLG 189
>AL139082-7|CAI12895.1| 507|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 3 protein.
Length = 507
Score = 97.5 bits (232), Expect = 5e-20
Identities = 51/146 (34%), Positives = 81/146 (55%), Gaps = 2/146 (1%)
Frame = +2
Query: 296 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIR--KDQHIDETRGRRWF 469
+E ++ +KH N++ F ++ E +YIVMEY + G L+ I+ K + E WF
Sbjct: 49 KEAVLLAKMKHPNIVAFKESFEAEGHLYIVMEYCDGGDLMQKIKQQKGKLFPEDMILNWF 108
Query: 470 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 649
Q+ V++ H++ V+HRDIK +N+ + +KL DFG AR P A + T+ G
Sbjct: 109 TQMCLGVNHIHKKRVLHRDIKSKNIFLTQNGKVKLGDFGSARLLSNP----MAFACTYVG 164
Query: 650 SYAYASPEILKGVPYRPQDSDVWSMG 727
+ Y PEI + +PY SD+WS+G
Sbjct: 165 TPYYVPPEIWENLPYN-NKSDIWSLG 189
>AK131359-1|BAD18511.1| 510|Homo sapiens protein ( Homo sapiens
cDNA FLJ16392 fis, clone TRACH2020048, moderately
similar to Mus musculus serine/threonine-protein kinase
NEK3 (Nek3) mRNA. ).
Length = 510
Score = 97.5 bits (232), Expect = 5e-20
Identities = 51/146 (34%), Positives = 81/146 (55%), Gaps = 2/146 (1%)
Frame = +2
Query: 296 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIR--KDQHIDETRGRRWF 469
+E ++ +KH N++ F ++ E +YIVMEY + G L+ I+ K + E WF
Sbjct: 70 KEAVLLAKMKHPNIVAFKESFEAEGHLYIVMEYCDGGDLMQKIKQQKGKLFPEDMILNWF 129
Query: 470 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 649
Q+ V++ H++ V+HRDIK +N+ + +KL DFG AR P A + T+ G
Sbjct: 130 TQMCLGVNHIHKKRVLHRDIKSKNIFLTQNGKVKLGDFGSARLLSNP----MAFACTYVG 185
Query: 650 SYAYASPEILKGVPYRPQDSDVWSMG 727
+ Y PEI + +PY SD+WS+G
Sbjct: 186 TPYYVPPEIWENLPYN-NKSDIWSLG 210
>AB072828-1|BAC15599.1| 489|Homo sapiens NIMA-related protein
kinase 3 protein.
Length = 489
Score = 97.5 bits (232), Expect = 5e-20
Identities = 51/146 (34%), Positives = 81/146 (55%), Gaps = 2/146 (1%)
Frame = +2
Query: 296 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIR--KDQHIDETRGRRWF 469
+E ++ +KH N++ F ++ E +YIVMEY + G L+ I+ K + E WF
Sbjct: 49 KEAVLLAKMKHPNIVAFKESFEAEGHLYIVMEYCDGGDLMQKIKQQKGKLFPEDMILNWF 108
Query: 470 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 649
Q+ V++ H++ V+HRDIK +N+ + +KL DFG AR P A + T+ G
Sbjct: 109 TQMCLGVNHIHKKRVLHRDIKSKNIFLTQNGKVKLGDFGSARLLSNP----MAFACTYVG 164
Query: 650 SYAYASPEILKGVPYRPQDSDVWSMG 727
+ Y PEI + +PY SD+WS+G
Sbjct: 165 TPYYVPPEIWENLPYN-NKSDIWSLG 189
>Z29066-1|CAA82309.1| 445|Homo sapiens protein kinase protein.
Length = 445
Score = 97.1 bits (231), Expect = 6e-20
Identities = 60/160 (37%), Positives = 87/160 (54%), Gaps = 11/160 (6%)
Frame = +2
Query: 281 KKFLPREIEVVKGLKHENLIRFLQAI--ETTHRVYIVMEYAENGSLLDIIRKD----QHI 442
K+ L E+ +++ LKH N++R+ I T +YIVMEY E G L +I K Q++
Sbjct: 49 KQMLVSEVNLLRELKHPNIVRYYDRIIDRTNTTLYIVMEYCEGGDLASVITKGTKERQYL 108
Query: 443 DETRGRRWFKQLVEAVDYCHERG-----VVHRDIKCENLLMDHGLNIKLSDFGFARGHMK 607
DE R QL A+ CH R V+HRD+K N+ +D N+KL DFG AR
Sbjct: 109 DEEFVLRVMTQLTLALKECHRRSDGGHTVLHRDLKPANVFLDGKQNVKLGDFGLAR---- 164
Query: 608 PKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
N + ++TF G+ Y SPE + + Y + SD+WS+G
Sbjct: 165 ILNHDTSFAKTFVGTPYYMSPEQMNRMSYN-EKSDIWSLG 203
>U11050-1|AAA19558.1| 445|Homo sapiens NIMA-like protein kinase 1
protein.
Length = 445
Score = 97.1 bits (231), Expect = 6e-20
Identities = 60/160 (37%), Positives = 87/160 (54%), Gaps = 11/160 (6%)
Frame = +2
Query: 281 KKFLPREIEVVKGLKHENLIRFLQAI--ETTHRVYIVMEYAENGSLLDIIRKD----QHI 442
K+ L E+ +++ LKH N++R+ I T +YIVMEY E G L +I K Q++
Sbjct: 49 KQMLVSEVNLLRELKHPNIVRYYDRIIDRTNTTLYIVMEYCEGGDLASVITKGTKERQYL 108
Query: 443 DETRGRRWFKQLVEAVDYCHERG-----VVHRDIKCENLLMDHGLNIKLSDFGFARGHMK 607
DE R QL A+ CH R V+HRD+K N+ +D N+KL DFG AR
Sbjct: 109 DEEFVLRVMTQLTLALKECHRRSDGGHTVLHRDLKPANVFLDGKQNVKLGDFGLAR---- 164
Query: 608 PKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
N + ++TF G+ Y SPE + + Y + SD+WS+G
Sbjct: 165 ILNHDTSFAKTFVGTPYYMSPEQMNRMSYN-EKSDIWSLG 203
>BT019729-1|AAV38534.1| 445|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 2 protein.
Length = 445
Score = 97.1 bits (231), Expect = 6e-20
Identities = 60/160 (37%), Positives = 87/160 (54%), Gaps = 11/160 (6%)
Frame = +2
Query: 281 KKFLPREIEVVKGLKHENLIRFLQAI--ETTHRVYIVMEYAENGSLLDIIRKD----QHI 442
K+ L E+ +++ LKH N++R+ I T +YIVMEY E G L +I K Q++
Sbjct: 49 KQMLVSEVNLLRELKHPNIVRYYDRIIDRTNTTLYIVMEYCEGGDLASVITKGTKERQYL 108
Query: 443 DETRGRRWFKQLVEAVDYCHERG-----VVHRDIKCENLLMDHGLNIKLSDFGFARGHMK 607
DE R QL A+ CH R V+HRD+K N+ +D N+KL DFG AR
Sbjct: 109 DEEFVLRVMTQLTLALKECHRRSDGGHTVLHRDLKPANVFLDGKQNVKLGDFGLAR---- 164
Query: 608 PKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
N + ++TF G+ Y SPE + + Y + SD+WS+G
Sbjct: 165 ILNHDTSFAKTFVGTPYYMSPEQMNRMSYN-EKSDIWSLG 203
>BC065932-1|AAH65932.1| 214|Homo sapiens NEK2 protein protein.
Length = 214
Score = 97.1 bits (231), Expect = 6e-20
Identities = 60/160 (37%), Positives = 87/160 (54%), Gaps = 11/160 (6%)
Frame = +2
Query: 281 KKFLPREIEVVKGLKHENLIRFLQAI--ETTHRVYIVMEYAENGSLLDIIRKD----QHI 442
K+ L E+ +++ LKH N++R+ I T +YIVMEY E G L +I K Q++
Sbjct: 49 KQMLVSEVNLLRELKHPNIVRYYDRIIDRTNTTLYIVMEYCEGGDLASVITKGTKERQYL 108
Query: 443 DETRGRRWFKQLVEAVDYCHERG-----VVHRDIKCENLLMDHGLNIKLSDFGFARGHMK 607
DE R QL A+ CH R V+HRD+K N+ +D N+KL DFG AR
Sbjct: 109 DEEFVLRVMTQLTLALKECHRRSDGGHTVLHRDLKPANVFLDGKQNVKLGDFGLAR---- 164
Query: 608 PKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
N + ++TF G+ Y SPE + + Y + SD+WS+G
Sbjct: 165 ILNHDTSFAKTFVGTPYYMSPEQMNRMSYN-EKSDIWSLG 203
>BC063885-1|AAH63885.1| 708|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 5 protein.
Length = 708
Score = 97.1 bits (231), Expect = 6e-20
Identities = 58/175 (33%), Positives = 96/175 (54%), Gaps = 3/175 (1%)
Frame = +2
Query: 212 SDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVME 391
SD +C IK I+ F+ K+ +E+ +++ +KH N++ F + + R++IVME
Sbjct: 25 SDSKHC--VIKEIN-FEKMPIQEKEASKKEVILLEKMKHPNIVAFFNSFQENGRLFIVME 81
Query: 392 YAENGSLLDIIRKDQHI--DETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL-LMDHGL 562
Y + G L+ I + + + E + WF Q+ + + H+R ++HRDIK +N+ L +G+
Sbjct: 82 YCDGGDLMKRINRQRGVLFSEDQILGWFVQISLGLKHIHDRKILHRDIKAQNIFLSKNGM 141
Query: 563 NIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
KL DFG AR N L+ T G+ Y SPEI + PY +D+WS+G
Sbjct: 142 VAKLGDFGIAR----VLNNSMELARTCIGTPYYLSPEICQNKPYN-NKTDIWSLG 191
>BC052807-1|AAH52807.1| 326|Homo sapiens NEK2 protein protein.
Length = 326
Score = 97.1 bits (231), Expect = 6e-20
Identities = 60/160 (37%), Positives = 87/160 (54%), Gaps = 11/160 (6%)
Frame = +2
Query: 281 KKFLPREIEVVKGLKHENLIRFLQAI--ETTHRVYIVMEYAENGSLLDIIRKD----QHI 442
K+ L E+ +++ LKH N++R+ I T +YIVMEY E G L +I K Q++
Sbjct: 49 KQMLVSEVNLLRELKHPNIVRYYDRIIDRTNTTLYIVMEYCEGGDLASVITKGTKERQYL 108
Query: 443 DETRGRRWFKQLVEAVDYCHERG-----VVHRDIKCENLLMDHGLNIKLSDFGFARGHMK 607
DE R QL A+ CH R V+HRD+K N+ +D N+KL DFG AR
Sbjct: 109 DEEFVLRVMTQLTLALKECHRRSDGGHTVLHRDLKPANVFLDGKQNVKLGDFGLAR---- 164
Query: 608 PKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
N + ++TF G+ Y SPE + + Y + SD+WS+G
Sbjct: 165 ILNHDTSFAKTFVGTPYYMSPEQMNRMSYN-EKSDIWSLG 203
>BC043502-1|AAH43502.2| 445|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 2 protein.
Length = 445
Score = 97.1 bits (231), Expect = 6e-20
Identities = 60/160 (37%), Positives = 87/160 (54%), Gaps = 11/160 (6%)
Frame = +2
Query: 281 KKFLPREIEVVKGLKHENLIRFLQAI--ETTHRVYIVMEYAENGSLLDIIRKD----QHI 442
K+ L E+ +++ LKH N++R+ I T +YIVMEY E G L +I K Q++
Sbjct: 49 KQMLVSEVNLLRELKHPNIVRYYDRIIDRTNTTLYIVMEYCEGGDLASVITKGTKERQYL 108
Query: 443 DETRGRRWFKQLVEAVDYCHERG-----VVHRDIKCENLLMDHGLNIKLSDFGFARGHMK 607
DE R QL A+ CH R V+HRD+K N+ +D N+KL DFG AR
Sbjct: 109 DEEFVLRVMTQLTLALKECHRRSDGGHTVLHRDLKPANVFLDGKQNVKLGDFGLAR---- 164
Query: 608 PKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
N + ++TF G+ Y SPE + + Y + SD+WS+G
Sbjct: 165 ILNHDTSFAKTFVGTPYYMSPEQMNRMSYN-EKSDIWSLG 203
>AY045701-1|AAK92212.1| 384|Homo sapiens NEK2B protein kinase
protein.
Length = 384
Score = 97.1 bits (231), Expect = 6e-20
Identities = 60/160 (37%), Positives = 87/160 (54%), Gaps = 11/160 (6%)
Frame = +2
Query: 281 KKFLPREIEVVKGLKHENLIRFLQAI--ETTHRVYIVMEYAENGSLLDIIRKD----QHI 442
K+ L E+ +++ LKH N++R+ I T +YIVMEY E G L +I K Q++
Sbjct: 49 KQMLVSEVNLLRELKHPNIVRYYDRIIDRTNTTLYIVMEYCEGGDLASVITKGTKERQYL 108
Query: 443 DETRGRRWFKQLVEAVDYCHERG-----VVHRDIKCENLLMDHGLNIKLSDFGFARGHMK 607
DE R QL A+ CH R V+HRD+K N+ +D N+KL DFG AR
Sbjct: 109 DEEFVLRVMTQLTLALKECHRRSDGGHTVLHRDLKPANVFLDGKQNVKLGDFGLAR---- 164
Query: 608 PKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
N + ++TF G+ Y SPE + + Y + SD+WS+G
Sbjct: 165 ILNHDTSFAKTFVGTPYYMSPEQMNRMSYN-EKSDIWSLG 203
>AL356310-2|CAH72901.1| 445|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 2 protein.
Length = 445
Score = 97.1 bits (231), Expect = 6e-20
Identities = 60/160 (37%), Positives = 87/160 (54%), Gaps = 11/160 (6%)
Frame = +2
Query: 281 KKFLPREIEVVKGLKHENLIRFLQAI--ETTHRVYIVMEYAENGSLLDIIRKD----QHI 442
K+ L E+ +++ LKH N++R+ I T +YIVMEY E G L +I K Q++
Sbjct: 49 KQMLVSEVNLLRELKHPNIVRYYDRIIDRTNTTLYIVMEYCEGGDLASVITKGTKERQYL 108
Query: 443 DETRGRRWFKQLVEAVDYCHERG-----VVHRDIKCENLLMDHGLNIKLSDFGFARGHMK 607
DE R QL A+ CH R V+HRD+K N+ +D N+KL DFG AR
Sbjct: 109 DEEFVLRVMTQLTLALKECHRRSDGGHTVLHRDLKPANVFLDGKQNVKLGDFGLAR---- 164
Query: 608 PKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
N + ++TF G+ Y SPE + + Y + SD+WS+G
Sbjct: 165 ILNHDTSFAKTFVGTPYYMSPEQMNRMSYN-EKSDIWSLG 203
>AL139082-5|CAI12892.2| 708|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 5 protein.
Length = 708
Score = 97.1 bits (231), Expect = 6e-20
Identities = 58/175 (33%), Positives = 96/175 (54%), Gaps = 3/175 (1%)
Frame = +2
Query: 212 SDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVME 391
SD +C IK I+ F+ K+ +E+ +++ +KH N++ F + + R++IVME
Sbjct: 25 SDSKHC--VIKEIN-FEKMPIQEKEASKKEVILLEKMKHPNIVAFFNSFQENGRLFIVME 81
Query: 392 YAENGSLLDIIRKDQHI--DETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL-LMDHGL 562
Y + G L+ I + + + E + WF Q+ + + H+R ++HRDIK +N+ L +G+
Sbjct: 82 YCDGGDLMKRINRQRGVLFSEDQILGWFVQISLGLKHIHDRKILHRDIKAQNIFLSKNGM 141
Query: 563 NIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
KL DFG AR N L+ T G+ Y SPEI + PY +D+WS+G
Sbjct: 142 VAKLGDFGIAR----VLNNSMELARTCIGTPYYLSPEICQNKPYN-NKTDIWSLG 191
>AK223353-1|BAD97073.1| 445|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 2 variant protein.
Length = 445
Score = 97.1 bits (231), Expect = 6e-20
Identities = 60/160 (37%), Positives = 87/160 (54%), Gaps = 11/160 (6%)
Frame = +2
Query: 281 KKFLPREIEVVKGLKHENLIRFLQAI--ETTHRVYIVMEYAENGSLLDIIRKD----QHI 442
K+ L E+ +++ LKH N++R+ I T +YIVMEY E G L +I K Q++
Sbjct: 49 KQMLVSEVNLLRELKHPNIVRYYDRIIDRTNTTLYIVMEYCEGGDLASVITKGTKERQYL 108
Query: 443 DETRGRRWFKQLVEAVDYCHERG-----VVHRDIKCENLLMDHGLNIKLSDFGFARGHMK 607
DE R QL A+ CH R V+HRD+K N+ +D N+KL DFG AR
Sbjct: 109 DEEFVLRVMTQLTLALKECHRRSDGGHTVLHRDLKPANVFLDGKQNVKLGDFGLAR---- 164
Query: 608 PKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
N + ++TF G+ Y SPE + + Y + SD+WS+G
Sbjct: 165 ILNHDTSFAKTFVGTPYYMSPEQMNRMSYN-EKSDIWSLG 203
>AB183428-1|BAF73616.1| 580|Homo sapiens maternal embryonic luecine
zipper kinase v3 protein.
Length = 580
Score = 97.1 bits (231), Expect = 6e-20
Identities = 49/113 (43%), Positives = 63/113 (55%)
Frame = +2
Query: 389 EYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNI 568
+Y G L D I + E R F+Q+V AV Y H +G HRD+K ENLL D +
Sbjct: 16 QYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKL 75
Query: 569 KLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
KL DFG KPK +T CGS AYA+PE+++G Y ++DVWSMG
Sbjct: 76 KLIDFGLC---AKPKGNKDYHLQTCCGSLAYAAPELIQGKSYLGSEADVWSMG 125
>U56998-1|AAC50637.1| 607|Homo sapiens putative serine/threonine
protein kinase PRK protein.
Length = 607
Score = 96.7 bits (230), Expect = 8e-20
Identities = 48/164 (29%), Positives = 89/164 (54%)
Frame = +2
Query: 236 AIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLL 415
A+K+I + + + ++ + EIE+ + L+H +++RF E +YI +E SL
Sbjct: 50 AVKVIPQSRVAKPHQREKILNEIELHRDLQHRHIVRFSHHFEDADNIYIFLELCSRKSLA 109
Query: 416 DIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFAR 595
I + + E R + +Q++ + Y H+RG++HRD+K N + + +K+ DFG A
Sbjct: 110 HIWKARHTLLEPEVRYYLRQILSGLKYLHQRGILHRDLKLGNFFITENMELKVGDFGLA- 168
Query: 596 GHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
++P +T CG+ Y +PE+L + P ++DVWS+G
Sbjct: 169 ARLEPPE---QRKKTICGTPNYVAPEVLLRQGHGP-EADVWSLG 208
>M55284-1|AAA60100.1| 682|Homo sapiens protein kinase C-L protein.
Length = 682
Score = 96.7 bits (230), Expect = 8e-20
Identities = 48/134 (35%), Positives = 81/134 (60%)
Frame = +2
Query: 326 HENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHE 505
H L + +T R++ VME+ G L+ I+K + DE R R + +++ A+ + H+
Sbjct: 412 HPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALMFLHD 471
Query: 506 RGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKG 685
+G+++RD+K +N+L+DH + KL+DFG + + NGV + TFCG+ Y +PEIL+
Sbjct: 472 KGIIYRDLKLDNVLLDHEGHCKLADFGMCKEGI--CNGV--TTATFCGTPDYIAPEILQE 527
Query: 686 VPYRPQDSDVWSMG 727
+ Y P D W+MG
Sbjct: 528 MLYGPA-VDWWAMG 540
>BC062616-1|AAH62616.1| 424|Homo sapiens protein serine kinase H1
protein.
Length = 424
Score = 96.7 bits (230), Expect = 8e-20
Identities = 59/167 (35%), Positives = 88/167 (52%), Gaps = 3/167 (1%)
Frame = +2
Query: 236 AIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLL 415
AIK+I G ++ E+ V++ ++H N+I+ ++ ET RVY+VME A G L
Sbjct: 125 AIKMIETKYREG---REVCESELRVLRRVRHANIIQLVEVFETQERVYMVMELATGGELF 181
Query: 416 DIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDH-GLNIK--LSDFG 586
D I E R + +++ V Y H G+ HRD+K ENLL H G + K ++DFG
Sbjct: 182 DRIIAKGSFTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFG 241
Query: 587 FARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
A K G L +T CG+ Y +PE+L PY D+W++G
Sbjct: 242 LASAR---KKGDDCLMKTTCGTPEYIAPEVLVRKPY-TNSVDMWALG 284
>BC037268-1|AAH37268.1| 683|Homo sapiens protein kinase C, eta
protein.
Length = 683
Score = 96.7 bits (230), Expect = 8e-20
Identities = 48/134 (35%), Positives = 81/134 (60%)
Frame = +2
Query: 326 HENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHE 505
H L + +T R++ VME+ G L+ I+K + DE R R + +++ A+ + H+
Sbjct: 413 HPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALMFLHD 472
Query: 506 RGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKG 685
+G+++RD+K +N+L+DH + KL+DFG + + NGV + TFCG+ Y +PEIL+
Sbjct: 473 KGIIYRDLKLDNVLLDHEGHCKLADFGMCKEGI--CNGV--TTATFCGTPDYIAPEILQE 528
Query: 686 VPYRPQDSDVWSMG 727
+ Y P D W+MG
Sbjct: 529 MLYGPA-VDWWAMG 541
>BC013899-1|AAH13899.1| 646|Homo sapiens polo-like kinase 3
(Drosophila) protein.
Length = 646
Score = 96.7 bits (230), Expect = 8e-20
Identities = 48/164 (29%), Positives = 89/164 (54%)
Frame = +2
Query: 236 AIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLL 415
A+K+I + + + ++ + EIE+ + L+H +++RF E +YI +E SL
Sbjct: 89 AVKVIPQSRVAKPHQREKILNEIELHRDLQHRHIVRFSHHFEDADNIYIFLELCSRKSLA 148
Query: 416 DIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFAR 595
I + + E R + +Q++ + Y H+RG++HRD+K N + + +K+ DFG A
Sbjct: 149 HIWKARHTLLEPEVRYYLRQILSGLKYLHQRGILHRDLKLGNFFITENMELKVGDFGLA- 207
Query: 596 GHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
++P +T CG+ Y +PE+L + P ++DVWS+G
Sbjct: 208 ARLEPPE---QRKKTICGTPNYVAPEVLLRQGHGP-EADVWSLG 247
>AY764184-1|AAU88146.1| 646|Homo sapiens polo-like kinase 3
(Drosophila) protein.
Length = 646
Score = 96.7 bits (230), Expect = 8e-20
Identities = 48/164 (29%), Positives = 89/164 (54%)
Frame = +2
Query: 236 AIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLL 415
A+K+I + + + ++ + EIE+ + L+H +++RF E +YI +E SL
Sbjct: 89 AVKVIPQSRVAKPHQREKILNEIELHRDLQHRHIVRFSHHFEDADNIYIFLELCSRKSLA 148
Query: 416 DIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFAR 595
I + + E R + +Q++ + Y H+RG++HRD+K N + + +K+ DFG A
Sbjct: 149 HIWKARHTLLEPEVRYYLRQILSGLKYLHQRGILHRDLKLGNFFITENMELKVGDFGLA- 207
Query: 596 GHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
++P +T CG+ Y +PE+L + P ++DVWS+G
Sbjct: 208 ARLEPPE---QRKKTICGTPNYVAPEVLLRQGHGP-EADVWSLG 247
>AL592166-11|CAI13006.1| 646|Homo sapiens polo-like kinase 3
(Drosophila) protein.
Length = 646
Score = 96.7 bits (230), Expect = 8e-20
Identities = 48/164 (29%), Positives = 89/164 (54%)
Frame = +2
Query: 236 AIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLL 415
A+K+I + + + ++ + EIE+ + L+H +++RF E +YI +E SL
Sbjct: 89 AVKVIPQSRVAKPHQREKILNEIELHRDLQHRHIVRFSHHFEDADNIYIFLELCSRKSLA 148
Query: 416 DIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFAR 595
I + + E R + +Q++ + Y H+RG++HRD+K N + + +K+ DFG A
Sbjct: 149 HIWKARHTLLEPEVRYYLRQILSGLKYLHQRGILHRDLKLGNFFITENMELKVGDFGLA- 207
Query: 596 GHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
++P +T CG+ Y +PE+L + P ++DVWS+G
Sbjct: 208 ARLEPPE---QRKKTICGTPNYVAPEVLLRQGHGP-EADVWSLG 247
>AJ272212-1|CAB91984.1| 424|Homo sapiens protein serine kinase
protein.
Length = 424
Score = 96.7 bits (230), Expect = 8e-20
Identities = 59/167 (35%), Positives = 88/167 (52%), Gaps = 3/167 (1%)
Frame = +2
Query: 236 AIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLL 415
AIK+I G ++ E+ V++ ++H N+I+ ++ ET RVY+VME A G L
Sbjct: 125 AIKMIETKYREG---REVCESELRVLRRVRHANIIQLVEVFETQERVYMVMELATGGELF 181
Query: 416 DIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDH-GLNIK--LSDFG 586
D I E R + +++ V Y H G+ HRD+K ENLL H G + K ++DFG
Sbjct: 182 DRIIAKGSFTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFG 241
Query: 587 FARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
A K G L +T CG+ Y +PE+L PY D+W++G
Sbjct: 242 LASAR---KKGDDCLMKTTCGTPEYIAPEVLVRKPY-TNSVDMWALG 284
>AB209875-1|BAD93112.1| 621|Homo sapiens polo-like kinase 3 variant
protein.
Length = 621
Score = 96.7 bits (230), Expect = 8e-20
Identities = 48/164 (29%), Positives = 89/164 (54%)
Frame = +2
Query: 236 AIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLL 415
A+K+I + + + ++ + EIE+ + L+H +++RF E +YI +E SL
Sbjct: 64 AVKVIPQSRVAKPHQREKILNEIELHRDLQHRHIVRFSHHFEDADNIYIFLELCSRKSLA 123
Query: 416 DIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFAR 595
I + + E R + +Q++ + Y H+RG++HRD+K N + + +K+ DFG A
Sbjct: 124 HIWKARHTLLEPEVRYYLRQILSGLKYLHQRGILHRDLKLGNFFITENMELKVGDFGLA- 182
Query: 596 GHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
++P +T CG+ Y +PE+L + P ++DVWS+G
Sbjct: 183 ARLEPPE---QRKKTICGTPNYVAPEVLLRQGHGP-EADVWSLG 222
>Z29067-1|CAA82310.1| 459|Homo sapiens protein kinase protein.
Length = 459
Score = 96.3 bits (229), Expect = 1e-19
Identities = 50/138 (36%), Positives = 77/138 (55%), Gaps = 2/138 (1%)
Frame = +2
Query: 320 LKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIR--KDQHIDETRGRRWFKQLVEAVD 493
+KH N++ F ++ E +YIVMEY + G L+ I+ K + E WF Q+ V+
Sbjct: 10 MKHPNIVAFKESFEAEGHLYIVMEYCDGGDLMQKIKQQKGKLFPEDMILNWFTQMCLGVN 69
Query: 494 YCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPE 673
+ H++ V+HRDIK +N+ + +KL DFG AR P A + T+ G+ Y PE
Sbjct: 70 HIHKKRVLHRDIKSKNIFLTQNGKVKLGDFGSARLLSNP----MAFACTYVGTPYYVPPE 125
Query: 674 ILKGVPYRPQDSDVWSMG 727
I + +PY SD+WS+G
Sbjct: 126 IWENLPYN-NKSDIWSLG 142
>AJ293866-1|CAC10659.1| 646|Homo sapiens FNK serine/threonine
protein kinase protein.
Length = 646
Score = 96.3 bits (229), Expect = 1e-19
Identities = 48/164 (29%), Positives = 89/164 (54%)
Frame = +2
Query: 236 AIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLL 415
A+K+I + + + ++ + EIE+ + L+H +++RF E +YI +E SL
Sbjct: 89 AVKVIPQSRVVKPHQREKILNEIELHRDLQHRHIVRFSHHFEDADNIYIFLELCSRKSLA 148
Query: 416 DIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFAR 595
I + + E R + +Q++ + Y H+RG++HRD+K N + + +K+ DFG A
Sbjct: 149 HIWKARHTLLEPEVRYYLRQILSGLKYLHQRGILHRDLKLGNFFITENMELKVGDFGLA- 207
Query: 596 GHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
++P +T CG+ Y +PE+L + P ++DVWS+G
Sbjct: 208 ARLEPPE---QRKKTICGTPNYVAPEVLLRQGHGP-EADVWSLG 247
>L24959-1|AAA18251.1| 473|Homo sapiens calcium/calmodulin dependent
protein kinase protein.
Length = 473
Score = 95.9 bits (228), Expect = 1e-19
Identities = 57/152 (37%), Positives = 85/152 (55%), Gaps = 3/152 (1%)
Frame = +2
Query: 281 KKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGR 460
KK + EI V+ L H N+I+ + ET + +V+E G L D I + + E
Sbjct: 83 KKIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAA 142
Query: 461 RWFKQLVEAVDYCHERGVVHRDIKCENLLM---DHGLNIKLSDFGFARGHMKPKNGVFAL 631
KQ++EAV Y HE G+VHRD+K ENLL +K++DFG ++ ++ V L
Sbjct: 143 DAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSK---IVEHQV--L 197
Query: 632 SETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
+T CG+ Y +PEIL+G Y P + D+WS+G
Sbjct: 198 MKTVCGTPGYCAPEILRGCAYGP-EVDMWSVG 228
>L17000-1|AAA35639.1| 473|Homo sapiens calcium/calmodulin-dependent
protein kinase protein.
Length = 473
Score = 95.9 bits (228), Expect = 1e-19
Identities = 57/152 (37%), Positives = 85/152 (55%), Gaps = 3/152 (1%)
Frame = +2
Query: 281 KKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGR 460
KK + EI V+ L H N+I+ + ET + +V+E G L D I + + E
Sbjct: 83 KKIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAA 142
Query: 461 RWFKQLVEAVDYCHERGVVHRDIKCENLLM---DHGLNIKLSDFGFARGHMKPKNGVFAL 631
KQ++EAV Y HE G+VHRD+K ENLL +K++DFG ++ ++ V L
Sbjct: 143 DAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSK---IVEHQV--L 197
Query: 632 SETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
+T CG+ Y +PEIL+G Y P + D+WS+G
Sbjct: 198 MKTVCGTPGYCAPEILRGCAYGP-EVDMWSVG 228
>D30742-1|BAA06403.1| 473|Homo sapiens calmodulin-dependent protein
kinase IV protein.
Length = 473
Score = 95.9 bits (228), Expect = 1e-19
Identities = 57/152 (37%), Positives = 85/152 (55%), Gaps = 3/152 (1%)
Frame = +2
Query: 281 KKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGR 460
KK + EI V+ L H N+I+ + ET + +V+E G L D I + + E
Sbjct: 83 KKIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAA 142
Query: 461 RWFKQLVEAVDYCHERGVVHRDIKCENLLM---DHGLNIKLSDFGFARGHMKPKNGVFAL 631
KQ++EAV Y HE G+VHRD+K ENLL +K++DFG ++ ++ V L
Sbjct: 143 DAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSK---IVEHQV--L 197
Query: 632 SETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
+T CG+ Y +PEIL+G Y P + D+WS+G
Sbjct: 198 MKTVCGTPGYCAPEILRGCAYGP-EVDMWSVG 228
>BC025687-1|AAH25687.1| 473|Homo sapiens
calcium/calmodulin-dependent protein kinase IV protein.
Length = 473
Score = 95.9 bits (228), Expect = 1e-19
Identities = 57/152 (37%), Positives = 85/152 (55%), Gaps = 3/152 (1%)
Frame = +2
Query: 281 KKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGR 460
KK + EI V+ L H N+I+ + ET + +V+E G L D I + + E
Sbjct: 83 KKIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAA 142
Query: 461 RWFKQLVEAVDYCHERGVVHRDIKCENLLM---DHGLNIKLSDFGFARGHMKPKNGVFAL 631
KQ++EAV Y HE G+VHRD+K ENLL +K++DFG ++ ++ V L
Sbjct: 143 DAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSK---IVEHQV--L 197
Query: 632 SETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
+T CG+ Y +PEIL+G Y P + D+WS+G
Sbjct: 198 MKTVCGTPGYCAPEILRGCAYGP-EVDMWSVG 228
>BC016695-1|AAH16695.2| 503|Homo sapiens CAMK4 protein protein.
Length = 503
Score = 95.9 bits (228), Expect = 1e-19
Identities = 57/152 (37%), Positives = 85/152 (55%), Gaps = 3/152 (1%)
Frame = +2
Query: 281 KKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGR 460
KK + EI V+ L H N+I+ + ET + +V+E G L D I + + E
Sbjct: 113 KKIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAA 172
Query: 461 RWFKQLVEAVDYCHERGVVHRDIKCENLLM---DHGLNIKLSDFGFARGHMKPKNGVFAL 631
KQ++EAV Y HE G+VHRD+K ENLL +K++DFG ++ ++ V L
Sbjct: 173 DAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSK---IVEHQV--L 227
Query: 632 SETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
+T CG+ Y +PEIL+G Y P + D+WS+G
Sbjct: 228 MKTVCGTPGYCAPEILRGCAYGP-EVDMWSVG 258
>BC041799-1|AAH41799.1| 592|Homo sapiens CDKL3 protein protein.
Length = 592
Score = 95.5 bits (227), Expect = 2e-19
Identities = 56/192 (29%), Positives = 99/192 (51%), Gaps = 2/192 (1%)
Frame = +2
Query: 170 LGEMSAEPTATVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFL 349
LG++ TV N + I ++ P + K REI+ +K HENL+ +
Sbjct: 7 LGKVGEGSYGTVMKCKHKNTGQIVAIKIFYERPEQSVNKIAMREIKFLKQFHHENLVNLI 66
Query: 350 QAIETTHRVYIVMEYAENGSLLDIIRKDQH-IDETRGRRWFKQLVEAVDYCHERGVVHRD 526
+ ++++V E+ ++ ++LD ++ H ++ R R++ Q++ A+DY H ++HRD
Sbjct: 67 EVFRQKKKIHLVFEFIDH-TVLDELQHYCHGLESKRLRKYLFQILRAIDYLHSNNIIHRD 125
Query: 527 IKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPE-ILKGVPYRPQ 703
IK EN+L+ KL DFGFAR P + + + + Y +PE +LK Y +
Sbjct: 126 IKPENILVSQSGITKLCDFGFARTLAAPGD----IYTDYVATRWYRAPELVLKDTSY-GK 180
Query: 704 DSDVWSMGSSII 739
D+W++G II
Sbjct: 181 PVDIWALGCMII 192
>AF130372-1|AAF36509.1| 455|Homo sapiens serine-threonine protein
kinase NKIAMRE protein.
Length = 455
Score = 95.5 bits (227), Expect = 2e-19
Identities = 56/192 (29%), Positives = 99/192 (51%), Gaps = 2/192 (1%)
Frame = +2
Query: 170 LGEMSAEPTATVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFL 349
LG++ TV N + I ++ P + K REI+ +K HENL+ +
Sbjct: 7 LGKVGEGSYGTVMKCKHKNTGQIVAIKIFYERPEQSVNKIAMREIKFLKQFHHENLVNLI 66
Query: 350 QAIETTHRVYIVMEYAENGSLLDIIRKDQH-IDETRGRRWFKQLVEAVDYCHERGVVHRD 526
+ ++++V E+ ++ ++LD ++ H ++ R R++ Q++ A+DY H ++HRD
Sbjct: 67 EVFRQKKKIHLVFEFIDH-TVLDELQHYCHGLESKRLRKYLFQILRAIDYLHSNNIIHRD 125
Query: 527 IKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPE-ILKGVPYRPQ 703
IK EN+L+ KL DFGFAR P + + + + Y +PE +LK Y +
Sbjct: 126 IKPENILVSQSGITKLCDFGFARTLAAPGD----IYTDYVATRWYRAPELVLKDTSY-GK 180
Query: 704 DSDVWSMGSSII 739
D+W++G II
Sbjct: 181 PVDIWALGCMII 192
>BC063585-1|AAH63585.1| 1323|Homo sapiens PAS domain containing
serine/threonine kinase protein.
Length = 1323
Score = 95.1 bits (226), Expect = 2e-19
Identities = 53/147 (36%), Positives = 80/147 (54%), Gaps = 1/147 (0%)
Frame = +2
Query: 299 EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENG-SLLDIIRKDQHIDETRGRRWFKQ 475
EI ++ ++H N+I+ L E +VME +G L I + +DE F+Q
Sbjct: 1052 EIAILSRVEHANIIKVLDIFENQGFFQLVMEKHGSGLDLFAFIDRHPRLDEPLASYIFRQ 1111
Query: 476 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 655
LV AV Y + ++HRDIK EN+++ IKL DFG A + K L TFCG+
Sbjct: 1112 LVSAVGYLRLKDIIHRDIKDENIVIAEDFTIKLIDFGSAAYLERGK-----LFYTFCGTI 1166
Query: 656 AYASPEILKGVPYRPQDSDVWSMGSSI 736
Y +PE+L G PYR + ++WS+G ++
Sbjct: 1167 EYCAPEVLMGNPYRGPELEMWSLGVTL 1193
>BC043495-1|AAH43495.1| 953|Homo sapiens PASK protein protein.
Length = 953
Score = 95.1 bits (226), Expect = 2e-19
Identities = 53/147 (36%), Positives = 80/147 (54%), Gaps = 1/147 (0%)
Frame = +2
Query: 299 EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENG-SLLDIIRKDQHIDETRGRRWFKQ 475
EI ++ ++H N+I+ L E +VME +G L I + +DE F+Q
Sbjct: 682 EIAILSRVEHANIIKVLDIFENQGFFQLVMEKHGSGLDLFAFIDRHPRLDEPLASYIFRQ 741
Query: 476 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 655
LV AV Y + ++HRDIK EN+++ IKL DFG A + K L TFCG+
Sbjct: 742 LVSAVGYLRLKDIIHRDIKDENIVIAEDFTIKLIDFGSAAYLERGK-----LFYTFCGTI 796
Query: 656 AYASPEILKGVPYRPQDSDVWSMGSSI 736
Y +PE+L G PYR + ++WS+G ++
Sbjct: 797 EYCAPEVLMGNPYRGPELEMWSLGVTL 823
>BC035745-1|AAH35745.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 95.1 bits (226), Expect = 2e-19
Identities = 58/167 (34%), Positives = 88/167 (52%), Gaps = 3/167 (1%)
Frame = +2
Query: 236 AIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLL 415
A+K I K G + + EI V++ +KHEN++ E+ + +Y+VM+ G L
Sbjct: 50 AVKCIPKKALKGK--ESSIENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELF 107
Query: 416 DIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLL---MDHGLNIKLSDFG 586
D I + E +Q+++AV Y H G+VHRD+K ENLL D I +SDFG
Sbjct: 108 DRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFG 167
Query: 587 FARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
++ M+ K V + T CG+ Y +PE+L PY + D WS+G
Sbjct: 168 LSK--MEGKGDVMS---TACGTPGYVAPEVLAQKPY-SKAVDCWSIG 208
>BC032787-1|AAH32787.1| 476|Homo sapiens
calcium/calmodulin-dependent protein kinase IG protein.
Length = 476
Score = 95.1 bits (226), Expect = 2e-19
Identities = 60/167 (35%), Positives = 87/167 (52%), Gaps = 3/167 (1%)
Frame = +2
Query: 236 AIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLL 415
A+K I K A D L EI V+K +KHEN++ E+T Y+VM+ G L
Sbjct: 50 ALKCIKKSPAFRD---SSLENEIAVLKKIKHENIVTLEDIYESTTHYYLVMQLVSGGELF 106
Query: 416 DIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLM---DHGLNIKLSDFG 586
D I + E +Q++ AV Y HE G+VHRD+K ENLL + I ++DFG
Sbjct: 107 DRILERGVYTEKDASLVIQQVLSAVKYLHENGIVHRDLKPENLLYLTPEENSKIMITDFG 166
Query: 587 FARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
++ +NG+ + T CG+ Y +PE+L PY + D WS+G
Sbjct: 167 LSK---MEQNGIMS---TACGTPGYVAPEVLAQKPY-SKAVDCWSIG 206
>AY212935-1|AAP29964.1| 460|Homo sapiens CLICK III protein.
Length = 460
Score = 95.1 bits (226), Expect = 2e-19
Identities = 60/167 (35%), Positives = 87/167 (52%), Gaps = 3/167 (1%)
Frame = +2
Query: 236 AIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLL 415
A+K I K A D L EI V+K +KHEN++ E+T Y+VM+ G L
Sbjct: 50 ALKCIKKSPAFRD---SSLENEIAVLKKIKHENIVTLEDIYESTTHYYLVMQLVSGGELF 106
Query: 416 DIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLM---DHGLNIKLSDFG 586
D I + E +Q++ AV Y HE G+VHRD+K ENLL + I ++DFG
Sbjct: 107 DRILERGVYTEKDASLVIQQVLSAVKYLHENGIVHRDLKPENLLYLTPEENSKIMITDFG 166
Query: 587 FARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
++ +NG+ + T CG+ Y +PE+L PY + D WS+G
Sbjct: 167 LSK---MEQNGIMS---TACGTPGYVAPEVLAQKPY-SKAVDCWSIG 206
>AL731559-2|CAI14675.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 95.1 bits (226), Expect = 2e-19
Identities = 58/167 (34%), Positives = 88/167 (52%), Gaps = 3/167 (1%)
Frame = +2
Query: 236 AIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLL 415
A+K I K G + + EI V++ +KHEN++ E+ + +Y+VM+ G L
Sbjct: 50 AVKCIPKKALKGK--ESSIENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELF 107
Query: 416 DIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLL---MDHGLNIKLSDFG 586
D I + E +Q+++AV Y H G+VHRD+K ENLL D I +SDFG
Sbjct: 108 DRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFG 167
Query: 587 FARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
++ M+ K V + T CG+ Y +PE+L PY + D WS+G
Sbjct: 168 LSK--MEGKGDVMS---TACGTPGYVAPEVLAQKPY-SKAVDCWSIG 208
>AL731559-1|CAI14674.1| 357|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 357
Score = 95.1 bits (226), Expect = 2e-19
Identities = 58/167 (34%), Positives = 88/167 (52%), Gaps = 3/167 (1%)
Frame = +2
Query: 236 AIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLL 415
A+K I K G + + EI V++ +KHEN++ E+ + +Y+VM+ G L
Sbjct: 50 AVKCIPKKALKGK--ESSIENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELF 107
Query: 416 DIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLL---MDHGLNIKLSDFG 586
D I + E +Q+++AV Y H G+VHRD+K ENLL D I +SDFG
Sbjct: 108 DRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFG 167
Query: 587 FARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
++ M+ K V + T CG+ Y +PE+L PY + D WS+G
Sbjct: 168 LSK--MEGKGDVMS---TACGTPGYVAPEVLAQKPY-SKAVDCWSIG 208
>AL512783-2|CAH74036.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 95.1 bits (226), Expect = 2e-19
Identities = 58/167 (34%), Positives = 88/167 (52%), Gaps = 3/167 (1%)
Frame = +2
Query: 236 AIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLL 415
A+K I K G + + EI V++ +KHEN++ E+ + +Y+VM+ G L
Sbjct: 50 AVKCIPKKALKGK--ESSIENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELF 107
Query: 416 DIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLL---MDHGLNIKLSDFG 586
D I + E +Q+++AV Y H G+VHRD+K ENLL D I +SDFG
Sbjct: 108 DRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFG 167
Query: 587 FARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
++ M+ K V + T CG+ Y +PE+L PY + D WS+G
Sbjct: 168 LSK--MEGKGDVMS---TACGTPGYVAPEVLAQKPY-SKAVDCWSIG 208
>AL512783-1|CAH74035.1| 357|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 357
Score = 95.1 bits (226), Expect = 2e-19
Identities = 58/167 (34%), Positives = 88/167 (52%), Gaps = 3/167 (1%)
Frame = +2
Query: 236 AIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLL 415
A+K I K G + + EI V++ +KHEN++ E+ + +Y+VM+ G L
Sbjct: 50 AVKCIPKKALKGK--ESSIENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELF 107
Query: 416 DIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLL---MDHGLNIKLSDFG 586
D I + E +Q+++AV Y H G+VHRD+K ENLL D I +SDFG
Sbjct: 108 DRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFG 167
Query: 587 FARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
++ M+ K V + T CG+ Y +PE+L PY + D WS+G
Sbjct: 168 LSK--MEGKGDVMS---TACGTPGYVAPEVLAQKPY-SKAVDCWSIG 208
>AL512284-2|CAH71694.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 95.1 bits (226), Expect = 2e-19
Identities = 58/167 (34%), Positives = 88/167 (52%), Gaps = 3/167 (1%)
Frame = +2
Query: 236 AIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLL 415
A+K I K G + + EI V++ +KHEN++ E+ + +Y+VM+ G L
Sbjct: 50 AVKCIPKKALKGK--ESSIENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELF 107
Query: 416 DIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLL---MDHGLNIKLSDFG 586
D I + E +Q+++AV Y H G+VHRD+K ENLL D I +SDFG
Sbjct: 108 DRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFG 167
Query: 587 FARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
++ M+ K V + T CG+ Y +PE+L PY + D WS+G
Sbjct: 168 LSK--MEGKGDVMS---TACGTPGYVAPEVLAQKPY-SKAVDCWSIG 208
>AL512284-1|CAH71693.1| 357|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 357
Score = 95.1 bits (226), Expect = 2e-19
Identities = 58/167 (34%), Positives = 88/167 (52%), Gaps = 3/167 (1%)
Frame = +2
Query: 236 AIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLL 415
A+K I K G + + EI V++ +KHEN++ E+ + +Y+VM+ G L
Sbjct: 50 AVKCIPKKALKGK--ESSIENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELF 107
Query: 416 DIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLL---MDHGLNIKLSDFG 586
D I + E +Q+++AV Y H G+VHRD+K ENLL D I +SDFG
Sbjct: 108 DRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFG 167
Query: 587 FARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
++ M+ K V + T CG+ Y +PE+L PY + D WS+G
Sbjct: 168 LSK--MEGKGDVMS---TACGTPGYVAPEVLAQKPY-SKAVDCWSIG 208
>AL391314-2|CAI14410.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 95.1 bits (226), Expect = 2e-19
Identities = 58/167 (34%), Positives = 88/167 (52%), Gaps = 3/167 (1%)
Frame = +2
Query: 236 AIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLL 415
A+K I K G + + EI V++ +KHEN++ E+ + +Y+VM+ G L
Sbjct: 50 AVKCIPKKALKGK--ESSIENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELF 107
Query: 416 DIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLL---MDHGLNIKLSDFG 586
D I + E +Q+++AV Y H G+VHRD+K ENLL D I +SDFG
Sbjct: 108 DRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFG 167
Query: 587 FARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
++ M+ K V + T CG+ Y +PE+L PY + D WS+G
Sbjct: 168 LSK--MEGKGDVMS---TACGTPGYVAPEVLAQKPY-SKAVDCWSIG 208
>AL391314-1|CAI14409.1| 357|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 357
Score = 95.1 bits (226), Expect = 2e-19
Identities = 58/167 (34%), Positives = 88/167 (52%), Gaps = 3/167 (1%)
Frame = +2
Query: 236 AIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLL 415
A+K I K G + + EI V++ +KHEN++ E+ + +Y+VM+ G L
Sbjct: 50 AVKCIPKKALKGK--ESSIENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELF 107
Query: 416 DIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLL---MDHGLNIKLSDFG 586
D I + E +Q+++AV Y H G+VHRD+K ENLL D I +SDFG
Sbjct: 108 DRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFG 167
Query: 587 FARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
++ M+ K V + T CG+ Y +PE+L PY + D WS+G
Sbjct: 168 LSK--MEGKGDVMS---TACGTPGYVAPEVLAQKPY-SKAVDCWSIG 208
>AL049688-1|CAB41259.1| 481|Homo sapiens hypothetical protein
protein.
Length = 481
Score = 95.1 bits (226), Expect = 2e-19
Identities = 60/167 (35%), Positives = 87/167 (52%), Gaps = 3/167 (1%)
Frame = +2
Query: 236 AIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLL 415
A+K I K A D L EI V+K +KHEN++ E+T Y+VM+ G L
Sbjct: 55 ALKCIKKSPAFRD---SSLENEIAVLKKIKHENIVTLEDIYESTTHYYLVMQLVSGGELF 111
Query: 416 DIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLM---DHGLNIKLSDFG 586
D I + E +Q++ AV Y HE G+VHRD+K ENLL + I ++DFG
Sbjct: 112 DRILERGVYTEKDASLVIQQVLSAVKYLHENGIVHRDLKPENLLYLTPEENSKIMITDFG 171
Query: 587 FARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
++ +NG+ + T CG+ Y +PE+L PY + D WS+G
Sbjct: 172 LSK---MEQNGIMS---TACGTPGYVAPEVLAQKPY-SKAVDCWSIG 211
>AL023754-3|CAI19991.1| 476|Homo sapiens
calcium/calmodulin-dependent protein kinase IG protein.
Length = 476
Score = 95.1 bits (226), Expect = 2e-19
Identities = 60/167 (35%), Positives = 87/167 (52%), Gaps = 3/167 (1%)
Frame = +2
Query: 236 AIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLL 415
A+K I K A D L EI V+K +KHEN++ E+T Y+VM+ G L
Sbjct: 50 ALKCIKKSPAFRD---SSLENEIAVLKKIKHENIVTLEDIYESTTHYYLVMQLVSGGELF 106
Query: 416 DIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLM---DHGLNIKLSDFG 586
D I + E +Q++ AV Y HE G+VHRD+K ENLL + I ++DFG
Sbjct: 107 DRILERGVYTEKDASLVIQQVLSAVKYLHENGIVHRDLKPENLLYLTPEENSKIMITDFG 166
Query: 587 FARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
++ +NG+ + T CG+ Y +PE+L PY + D WS+G
Sbjct: 167 LSK---MEQNGIMS---TACGTPGYVAPEVLAQKPY-SKAVDCWSIG 206
>AF428261-1|AAL28100.1| 476|Homo sapiens
calcium/calmodulin-dependent protein kinase I gamma
protein.
Length = 476
Score = 95.1 bits (226), Expect = 2e-19
Identities = 60/167 (35%), Positives = 87/167 (52%), Gaps = 3/167 (1%)
Frame = +2
Query: 236 AIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLL 415
A+K I K A D L EI V+K +KHEN++ E+T Y+VM+ G L
Sbjct: 50 ALKCIKKSPAFRD---SSLENEIAVLKKIKHENIVTLEDIYESTTHYYLVMQLVSGGELF 106
Query: 416 DIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLM---DHGLNIKLSDFG 586
D I + E +Q++ AV Y HE G+VHRD+K ENLL + I ++DFG
Sbjct: 107 DRILERGVYTEKDASLVIQQVLSAVKYLHENGIVHRDLKPENLLYLTPEENSKIMITDFG 166
Query: 587 FARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
++ +NG+ + T CG+ Y +PE+L PY + D WS+G
Sbjct: 167 LSK---MEQNGIMS---TACGTPGYVAPEVLAQKPY-SKAVDCWSIG 206
>AF387103-1|AAK69752.1| 1323|Homo sapiens PAS-kinase protein.
Length = 1323
Score = 95.1 bits (226), Expect = 2e-19
Identities = 53/147 (36%), Positives = 80/147 (54%), Gaps = 1/147 (0%)
Frame = +2
Query: 299 EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENG-SLLDIIRKDQHIDETRGRRWFKQ 475
EI ++ ++H N+I+ L E +VME +G L I + +DE F+Q
Sbjct: 1052 EIAILSRVEHANIIKVLDIFENQGFFQLVMEKHGSGLDLFAFIDRHPRLDEPLASYIFRQ 1111
Query: 476 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 655
LV AV Y + ++HRDIK EN+++ IKL DFG A + K L TFCG+
Sbjct: 1112 LVSAVGYLRLKDIIHRDIKDENIVIAEDFTIKLIDFGSAAYLERGK-----LFYTFCGTI 1166
Query: 656 AYASPEILKGVPYRPQDSDVWSMGSSI 736
Y +PE+L G PYR + ++WS+G ++
Sbjct: 1167 EYCAPEVLMGNPYRGPELEMWSLGVTL 1193
>AF286366-1|AAG00534.1| 357|Homo sapiens CamKI-like protein kinase
protein.
Length = 357
Score = 95.1 bits (226), Expect = 2e-19
Identities = 58/167 (34%), Positives = 88/167 (52%), Gaps = 3/167 (1%)
Frame = +2
Query: 236 AIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLL 415
A+K I K G + + EI V++ +KHEN++ E+ + +Y+VM+ G L
Sbjct: 50 AVKCIPKKALKGK--ESSIENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELF 107
Query: 416 DIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLL---MDHGLNIKLSDFG 586
D I + E +Q+++AV Y H G+VHRD+K ENLL D I +SDFG
Sbjct: 108 DRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFG 167
Query: 587 FARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
++ M+ K V + T CG+ Y +PE+L PY + D WS+G
Sbjct: 168 LSK--MEGKGDVMS---TACGTPGYVAPEVLAQKPY-SKAVDCWSIG 208
>AB081726-1|BAC19846.1| 385|Homo sapiens CaM-kinase I delta
protein.
Length = 385
Score = 95.1 bits (226), Expect = 2e-19
Identities = 58/167 (34%), Positives = 88/167 (52%), Gaps = 3/167 (1%)
Frame = +2
Query: 236 AIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLL 415
A+K I K G + + EI V++ +KHEN++ E+ + +Y+VM+ G L
Sbjct: 50 AVKCIPKKALKGK--ESSIENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELF 107
Query: 416 DIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLL---MDHGLNIKLSDFG 586
D I + E +Q+++AV Y H G+VHRD+K ENLL D I +SDFG
Sbjct: 108 DRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFG 167
Query: 587 FARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
++ M+ K V + T CG+ Y +PE+L PY + D WS+G
Sbjct: 168 LSK--MEGKGDVMS---TACGTPGYVAPEVLAQKPY-SKAVDCWSIG 208
>U24153-1|AAA65442.1| 525|Homo sapiens p21-activated protein kinase
protein.
Length = 525
Score = 94.7 bits (225), Expect = 3e-19
Identities = 53/166 (31%), Positives = 96/166 (57%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
+VAIK I+ + P K+ + EI V+K LK+ N++ FL + +++VMEY GS
Sbjct: 274 EVAIKQINLQKQPK---KELIINEILVMKELKNPNIVNFLDSYLVGDELFVVMEYLAGGS 330
Query: 410 LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGF 589
L D++ + +DE + ++ ++A+++ H V+HRDIK +N+L+ ++KL+DFGF
Sbjct: 331 LTDVVTETACMDEAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGF 390
Query: 590 ARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
+ P+ + T G+ + +PE++ Y P+ D+WS+G
Sbjct: 391 C-AQITPEQ---SKRSTMVGTPYWMAPEVVTRKAYGPK-VDIWSLG 431
>L41816-1|AAA99458.1| 370|Homo sapiens cam kinase I protein.
Length = 370
Score = 94.7 bits (225), Expect = 3e-19
Identities = 65/197 (32%), Positives = 98/197 (49%), Gaps = 3/197 (1%)
Frame = +2
Query: 146 DVRTHDNVLGEMSAEPTATVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLK 325
D+ +VLG A +A R VAIK I+K G + + EI V+ +K
Sbjct: 18 DIYDFRDVLGT-GAFSEVILAEDKRTQKLVAIKCIAKEALEGK--EGSMENEIAVLHKIK 74
Query: 326 HENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHE 505
H N++ E+ +Y++M+ G L D I + E R Q+++AV Y H+
Sbjct: 75 HPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHD 134
Query: 506 RGVVHRDIKCENLL---MDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEI 676
G+VHRD+K ENLL +D I +SDFG ++ M+ V + T CG+ Y +PE+
Sbjct: 135 LGIVHRDLKPENLLYYSLDEDSKIMISDFGLSK--MEDPGSVLS---TACGTPGYVAPEV 189
Query: 677 LKGVPYRPQDSDVWSMG 727
L PY + D WS+G
Sbjct: 190 LAQKPY-SKAVDCWSIG 205
>BC106755-1|AAI06756.1| 370|Homo sapiens
calcium/calmodulin-dependent protein kinase I protein.
Length = 370
Score = 94.7 bits (225), Expect = 3e-19
Identities = 65/197 (32%), Positives = 98/197 (49%), Gaps = 3/197 (1%)
Frame = +2
Query: 146 DVRTHDNVLGEMSAEPTATVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLK 325
D+ +VLG A +A R VAIK I+K G + + EI V+ +K
Sbjct: 18 DIYDFRDVLGT-GAFSEVILAEDKRTQKLVAIKCIAKEALEGK--EGSMENEIAVLHKIK 74
Query: 326 HENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHE 505
H N++ E+ +Y++M+ G L D I + E R Q+++AV Y H+
Sbjct: 75 HPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHD 134
Query: 506 RGVVHRDIKCENLL---MDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEI 676
G+VHRD+K ENLL +D I +SDFG ++ M+ V + T CG+ Y +PE+
Sbjct: 135 LGIVHRDLKPENLLYYSLDEDSKIMISDFGLSK--MEDPGSVLS---TACGTPGYVAPEV 189
Query: 677 LKGVPYRPQDSDVWSMG 727
L PY + D WS+G
Sbjct: 190 LAQKPY-SKAVDCWSIG 205
>BC106754-1|AAI06755.1| 370|Homo sapiens
calcium/calmodulin-dependent protein kinase I protein.
Length = 370
Score = 94.7 bits (225), Expect = 3e-19
Identities = 65/197 (32%), Positives = 98/197 (49%), Gaps = 3/197 (1%)
Frame = +2
Query: 146 DVRTHDNVLGEMSAEPTATVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLK 325
D+ +VLG A +A R VAIK I+K G + + EI V+ +K
Sbjct: 18 DIYDFRDVLGT-GAFSEVILAEDKRTQKLVAIKCIAKEALEGK--EGSMENEIAVLHKIK 74
Query: 326 HENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHE 505
H N++ E+ +Y++M+ G L D I + E R Q+++AV Y H+
Sbjct: 75 HPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHD 134
Query: 506 RGVVHRDIKCENLL---MDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEI 676
G+VHRD+K ENLL +D I +SDFG ++ M+ V + T CG+ Y +PE+
Sbjct: 135 LGIVHRDLKPENLLYYSLDEDSKIMISDFGLSK--MEDPGSVLS---TACGTPGYVAPEV 189
Query: 677 LKGVPYRPQDSDVWSMG 727
L PY + D WS+G
Sbjct: 190 LAQKPY-SKAVDCWSIG 205
>U35146-1|AAC50918.1| 493|Homo sapiens p56 KKIAMRE protein kinase
protein.
Length = 493
Score = 94.3 bits (224), Expect = 4e-19
Identities = 53/165 (32%), Positives = 87/165 (52%), Gaps = 2/165 (1%)
Frame = +2
Query: 239 IKIISKFQAPGD--YLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSL 412
I I KF D +KK REI+++K L+HENL+ L+ + R Y+V E+ ++ L
Sbjct: 29 IVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENLVNLLEVCKKKKRWYLVFEFVDHTIL 88
Query: 413 LDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 592
D+ +D +++ Q++ + +CH ++HRDIK EN+L+ +KL DFGFA
Sbjct: 89 DDLELFPNGLDYQVVQKYLFQIINGIGFCHSHNIIHRDIKPENILVSQSGVVKLCDFGFA 148
Query: 593 RGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
R P + + + Y +PE+L G + DVW++G
Sbjct: 149 RTLAAPGE----VYTDYVATRWYRAPELLVGDVKYGKAVDVWAIG 189
>BC093981-1|AAH93981.1| 493|Homo sapiens cyclin-dependent
kinase-like 2 (CDC2-related kinase) protein.
Length = 493
Score = 94.3 bits (224), Expect = 4e-19
Identities = 53/165 (32%), Positives = 87/165 (52%), Gaps = 2/165 (1%)
Frame = +2
Query: 239 IKIISKFQAPGD--YLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSL 412
I I KF D +KK REI+++K L+HENL+ L+ + R Y+V E+ ++ L
Sbjct: 29 IVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENLVNLLEVCKKKKRWYLVFEFVDHTIL 88
Query: 413 LDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 592
D+ +D +++ Q++ + +CH ++HRDIK EN+L+ +KL DFGFA
Sbjct: 89 DDLELFPNGLDYQVVQKYLFQIINGIGFCHSHNIIHRDIKPENILVSQSGVVKLCDFGFA 148
Query: 593 RGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
R P + + + Y +PE+L G + DVW++G
Sbjct: 149 RTLAAPGE----VYTDYVATRWYRAPELLVGDVKYGKAVDVWAIG 189
>BC093646-1|AAH93646.1| 493|Homo sapiens cyclin-dependent
kinase-like 2 (CDC2-related kinase) protein.
Length = 493
Score = 94.3 bits (224), Expect = 4e-19
Identities = 53/165 (32%), Positives = 87/165 (52%), Gaps = 2/165 (1%)
Frame = +2
Query: 239 IKIISKFQAPGD--YLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSL 412
I I KF D +KK REI+++K L+HENL+ L+ + R Y+V E+ ++ L
Sbjct: 29 IVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENLVNLLEVCKKKKRWYLVFEFVDHTIL 88
Query: 413 LDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 592
D+ +D +++ Q++ + +CH ++HRDIK EN+L+ +KL DFGFA
Sbjct: 89 DDLELFPNGLDYQVVQKYLFQIINGIGFCHSHNIIHRDIKPENILVSQSGVVKLCDFGFA 148
Query: 593 RGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
R P + + + Y +PE+L G + DVW++G
Sbjct: 149 RTLAAPGE----VYTDYVATRWYRAPELLVGDVKYGKAVDVWAIG 189
>X66358-1|CAA47002.1| 358|Homo sapiens serine/threonine protein
kinase protein.
Length = 358
Score = 93.9 bits (223), Expect = 6e-19
Identities = 56/165 (33%), Positives = 86/165 (52%), Gaps = 2/165 (1%)
Frame = +2
Query: 239 IKIISKFQAPGD--YLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSL 412
I I KF D +KK REI ++K LKH NL+ L+ R+++V EY ++ L
Sbjct: 30 IVAIKKFLESEDDPVIKKIALREIRMLKQLKHPNLVNLLEVFRRKRRLHLVFEYCDHTVL 89
Query: 413 LDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 592
++ R + + E + Q ++AV++CH+ +HRD+K EN+L+ IKL DFGFA
Sbjct: 90 HELDRYQRGVPEHLVKSITWQTLQAVNFCHKHNCIHRDVKPENILITKHSVIKLCDFGFA 149
Query: 593 RGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
R P + + + Y SPE+L G DVW++G
Sbjct: 150 RLLTGPSD----YYTDYVATRWYRSPELLVGDTQYGPPVDVWAIG 190
>BC104977-1|AAI04978.1| 358|Homo sapiens cyclin-dependent
kinase-like 1 (CDC2-related kinase) protein.
Length = 358
Score = 93.9 bits (223), Expect = 6e-19
Identities = 56/165 (33%), Positives = 86/165 (52%), Gaps = 2/165 (1%)
Frame = +2
Query: 239 IKIISKFQAPGD--YLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSL 412
I I KF D +KK REI ++K LKH NL+ L+ R+++V EY ++ L
Sbjct: 30 IVAIKKFLESEDDPVIKKIALREIRMLKQLKHPNLVNLLEVFRRKRRLHLVFEYCDHTVL 89
Query: 413 LDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 592
++ R + + E + Q ++AV++CH+ +HRD+K EN+L+ IKL DFGFA
Sbjct: 90 HELDRYQRGVPEHLVKSITWQTLQAVNFCHKHNCIHRDVKPENILITKHSVIKLCDFGFA 149
Query: 593 RGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
R P + + + Y SPE+L G DVW++G
Sbjct: 150 RLLTGPSD----YYTDYVATRWYRSPELLVGDTQYGPPVDVWAIG 190
>BC013879-1|AAH13879.1| 685|Homo sapiens polo-like kinase 2
(Drosophila) protein.
Length = 685
Score = 93.9 bits (223), Expect = 6e-19
Identities = 48/169 (28%), Positives = 93/169 (55%)
Frame = +2
Query: 221 HNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAE 400
+N A KII + + ++ + +EIE+ + L H+++++F E +YI++EY
Sbjct: 104 NNKVYAAKIIPHSRVAKPHQREKIDKEIELHRILHHKHVVQFYHYFEDKENIYILLEYCS 163
Query: 401 NGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSD 580
S+ I++ + + E R + +Q+V + Y HE+ ++HRD+K N ++ + +K+ D
Sbjct: 164 RRSMAHILKARKVLTEPEVRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGD 223
Query: 581 FGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
FG A ++P + T CG+ Y SPE+L + +SD+W++G
Sbjct: 224 FGLA-ARLEP---LEHRRRTICGTPNYLSPEVLNKQGH-GCESDIWALG 267
>AY525548-1|AAS00095.1| 358|Homo sapiens cyclin-dependent
kinase-like 1 (CDC2-related kinase) protein.
Length = 358
Score = 93.9 bits (223), Expect = 6e-19
Identities = 56/165 (33%), Positives = 86/165 (52%), Gaps = 2/165 (1%)
Frame = +2
Query: 239 IKIISKFQAPGD--YLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSL 412
I I KF D +KK REI ++K LKH NL+ L+ R+++V EY ++ L
Sbjct: 30 IVAIKKFLESEDDPVIKKIALREIRMLKQLKHPNLVNLLEVFRRKRRLHLVFEYCDHTVL 89
Query: 413 LDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 592
++ R + + E + Q ++AV++CH+ +HRD+K EN+L+ IKL DFGFA
Sbjct: 90 HELDRYQRGVPEHLVKSITWQTLQAVNFCHKHNCIHRDVKPENILITKHSVIKLCDFGFA 149
Query: 593 RGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
R P + + + Y SPE+L G DVW++G
Sbjct: 150 RLLTGPSD----YYTDYVATRWYRSPELLVGDTQYGPPVDVWAIG 190
>AK098163-1|BAC05247.1| 372|Homo sapiens protein ( Homo sapiens
cDNA FLJ40844 fis, clone TRACH2014356, highly similar to
SERINE/THREONINE-PROTEIN KINASE SNK (EC 2.7.1.-). ).
Length = 372
Score = 93.9 bits (223), Expect = 6e-19
Identities = 48/169 (28%), Positives = 93/169 (55%)
Frame = +2
Query: 221 HNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAE 400
+N A KII + + ++ + +EIE+ + L H+++++F E +YI++EY
Sbjct: 97 NNKVYAAKIIPHSRVAKPHQREKIDKEIELHRILHHKHVVQFYHYFEDKENIYILLEYCS 156
Query: 401 NGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSD 580
S+ I++ + + E R + +Q+V + Y HE+ ++HRD+K N ++ + +K+ D
Sbjct: 157 RRSMAHILKARKVLTEPEVRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGD 216
Query: 581 FGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
FG A ++P + T CG+ Y SPE+L + +SD+W++G
Sbjct: 217 FGLA-ARLEP---LEHRRRTICGTPNYLSPEVLNKQGH-GCESDIWALG 260
>AF223574-1|AAF62897.1| 685|Homo sapiens serum-inducible kinase
protein.
Length = 685
Score = 93.9 bits (223), Expect = 6e-19
Identities = 48/169 (28%), Positives = 93/169 (55%)
Frame = +2
Query: 221 HNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAE 400
+N A KII + + ++ + +EIE+ + L H+++++F E +YI++EY
Sbjct: 104 NNKVYAAKIIPHSRVAKPHQREKIDKEIELHRILHHKHVVQFYHYFEDKENIYILLEYCS 163
Query: 401 NGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSD 580
S+ I++ + + E R + +Q+V + Y HE+ ++HRD+K N ++ + +K+ D
Sbjct: 164 RRSMAHILKARKVLTEPEVRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGD 223
Query: 581 FGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
FG A ++P + T CG+ Y SPE+L + +SD+W++G
Sbjct: 224 FGLA-ARLEP---LEHRRRTICGTPNYLSPEVLNKQGH-GCESDIWALG 267
>AF059617-1|AAC14573.1| 685|Homo sapiens serum-inducible kinase
protein.
Length = 685
Score = 93.9 bits (223), Expect = 6e-19
Identities = 48/169 (28%), Positives = 93/169 (55%)
Frame = +2
Query: 221 HNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAE 400
+N A KII + + ++ + +EIE+ + L H+++++F E +YI++EY
Sbjct: 104 NNKVYAAKIIPHSRVAKPHQREKIDKEIELHRILHHKHVVQFYHYFEDKENIYILLEYCS 163
Query: 401 NGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSD 580
S+ I++ + + E R + +Q+V + Y HE+ ++HRD+K N ++ + +K+ D
Sbjct: 164 RRSMAHILKARKVLTEPEVRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGD 223
Query: 581 FGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
FG A ++P + T CG+ Y SPE+L + +SD+W++G
Sbjct: 224 FGLA-ARLEP---LEHRRRTICGTPNYLSPEVLNKQGH-GCESDIWALG 267
>AB051552-1|BAB21856.1| 608|Homo sapiens KIAA1765 protein protein.
Length = 608
Score = 93.9 bits (223), Expect = 6e-19
Identities = 54/168 (32%), Positives = 90/168 (53%), Gaps = 4/168 (2%)
Frame = +2
Query: 236 AIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLL 415
A+KII K + G + + EI +++ L H N+++ + ET +Y+++EY + G L
Sbjct: 343 AMKIIDKSRLKGK--EDMVDSEILIIQSLSHPNIVKLHEVYETDMEIYLILEYVQGGDLF 400
Query: 416 DIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLM----DHGLNIKLSDF 583
D I + E L +A+ + H++ +VHRD+K ENLL+ D +KL+DF
Sbjct: 401 DAIIESVKFPEPDAALMIMDLCKALVHMHDKSIVHRDLKPENLLVQRNEDKSTTLKLADF 460
Query: 584 GFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
G A+ ++P +F T CG+ Y +PEIL Y + D+W+ G
Sbjct: 461 GLAKHVVRP---IF----TVCGTPTYVAPEILSEKGY-GLEVDMWAAG 500
>U79240-1|AAB50198.1| 458|Homo sapiens serine/threonine protein
kinase protein.
Length = 458
Score = 93.5 bits (222), Expect = 7e-19
Identities = 52/147 (35%), Positives = 79/147 (53%), Gaps = 1/147 (0%)
Frame = +2
Query: 299 EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENG-SLLDIIRKDQHIDETRGRRWFKQ 475
EI ++ ++H N+I+ L E +VME +G L I + +DE F+Q
Sbjct: 187 EIAILSRVEHANIIKVLDIFENQGFFQLVMEKHGSGLDLFAFIDRHPRLDEPLASYIFRQ 246
Query: 476 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 655
LV AV Y + ++HRD K EN+++ IKL DFG A + K L TFCG+
Sbjct: 247 LVSAVGYLRLKDIIHRDFKDENIVIAEDFTIKLIDFGSAAYLERGK-----LFYTFCGTI 301
Query: 656 AYASPEILKGVPYRPQDSDVWSMGSSI 736
Y +PE+L G PYR + ++WS+G ++
Sbjct: 302 EYCAPEVLMGNPYRGPELEMWSLGVTL 328
>AF080000-1|AAD23915.1| 802|Homo sapiens RSK-like protein kinase
RLPK protein.
Length = 802
Score = 93.5 bits (222), Expect = 7e-19
Identities = 67/198 (33%), Positives = 100/198 (50%), Gaps = 4/198 (2%)
Frame = +2
Query: 146 DVRTHDNVLGEMSAEPTATVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLK 325
D+ D LGE S + N A+KIISK ++ +EI +K +
Sbjct: 424 DLDLKDKPLGEGSFSICRKCVHK-KSNQAFAVKIISK------RMEANTQKEITALKLCE 476
Query: 326 -HENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCH 502
H N+++ + ++VME G L + I+K +H ET ++LV AV + H
Sbjct: 477 GHPNIVKLHEVFHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMH 536
Query: 503 ERGVVHRDIKCENLLM---DHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPE 673
+ GVVHRD+K ENLL + L IK+ DFGFAR +KP + +T C + YA+PE
Sbjct: 537 DVGVVHRDLKPENLLFTDENDNLEIKIIDFGFAR--LKPPDN--QPLKTPCFTLHYAAPE 592
Query: 674 ILKGVPYRPQDSDVWSMG 727
+L Y + D+WS+G
Sbjct: 593 LLNQNGY-DESCDLWSLG 609
Score = 71.7 bits (168), Expect = 3e-12
Identities = 34/132 (25%), Positives = 75/132 (56%), Gaps = 1/132 (0%)
Frame = +2
Query: 335 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 514
L+ A +T +++++++Y G L + + + E + + ++V A+++ H+ G+
Sbjct: 114 LVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALEHLHKLGI 173
Query: 515 VHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPY 694
++RDIK EN+L+D ++ L+DFG ++ + + + +FCG+ Y +P+I++G
Sbjct: 174 IYRDIKLENILLDSNGHVVLTDFGLSKEFVADET---ERAYSFCGTIEYMAPDIVRGGDS 230
Query: 695 -RPQDSDVWSMG 727
+ D WS+G
Sbjct: 231 GHDKAVDWWSLG 242
>AF074393-1|AAC31171.1| 802|Homo sapiens nuclear mitogen- and
stress-activated protein kinase-1 protein.
Length = 802
Score = 93.5 bits (222), Expect = 7e-19
Identities = 67/198 (33%), Positives = 100/198 (50%), Gaps = 4/198 (2%)
Frame = +2
Query: 146 DVRTHDNVLGEMSAEPTATVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLK 325
D+ D LGE S + N A+KIISK ++ +EI +K +
Sbjct: 424 DLDLKDKPLGEGSFSICRKCVHK-KSNQAFAVKIISK------RMEANTQKEITALKLCE 476
Query: 326 -HENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCH 502
H N+++ + ++VME G L + I+K +H ET ++LV AV + H
Sbjct: 477 GHPNIVKLHEVFHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMH 536
Query: 503 ERGVVHRDIKCENLLM---DHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPE 673
+ GVVHRD+K ENLL + L IK+ DFGFAR +KP + +T C + YA+PE
Sbjct: 537 DVGVVHRDLKPENLLFTDENDNLEIKIIDFGFAR--LKPPDN--QPLKTPCFTLHYAAPE 592
Query: 674 ILKGVPYRPQDSDVWSMG 727
+L Y + D+WS+G
Sbjct: 593 LLNQNGY-DESCDLWSLG 609
Score = 71.7 bits (168), Expect = 3e-12
Identities = 34/132 (25%), Positives = 75/132 (56%), Gaps = 1/132 (0%)
Frame = +2
Query: 335 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 514
L+ A +T +++++++Y G L + + + E + + ++V A+++ H+ G+
Sbjct: 114 LVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALEHLHKLGI 173
Query: 515 VHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPY 694
++RDIK EN+L+D ++ L+DFG ++ + + + +FCG+ Y +P+I++G
Sbjct: 174 IYRDIKLENILLDSNGHVVLTDFGLSKEFVADET---ERAYSFCGTIEYMAPDIVRGGDS 230
Query: 695 -RPQDSDVWSMG 727
+ D WS+G
Sbjct: 231 GHDKAVDWWSLG 242
>X65293-1|CAA46388.1| 737|Homo sapiens protein kinase C epsilon
protein.
Length = 737
Score = 93.1 bits (221), Expect = 1e-18
Identities = 48/135 (35%), Positives = 79/135 (58%)
Frame = +2
Query: 323 KHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCH 502
KH L + +T R++ VMEY G L+ I++ + DE R R + ++ A+ + H
Sbjct: 465 KHPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLH 524
Query: 503 ERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILK 682
+ GV++RD+K +N+L+D + KL+DFG + + NGV + TFCG+ Y +PEIL+
Sbjct: 525 QHGVIYRDLKLDNILLDAEGHCKLADFGMCKEGI--LNGV--TTTTFCGTPDYIAPEILQ 580
Query: 683 GVPYRPQDSDVWSMG 727
+ Y P D W++G
Sbjct: 581 ELEYGP-SVDWWALG 594
>BC128511-1|AAI28512.1| 1102|Homo sapiens KIAA0999 protein protein.
Length = 1102
Score = 93.1 bits (221), Expect = 1e-18
Identities = 45/94 (47%), Positives = 61/94 (64%)
Frame = +2
Query: 446 ETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVF 625
E RR FKQ+V AV +CH R +VHRD+K ENLL+D LNIK++DFGF+ +
Sbjct: 3 EKEARRKFKQIVTAVYFCHCRNIVHRDLKAENLLLDANLNIKIADFGFSNLFTPGQ---- 58
Query: 626 ALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
L +T+CGS YA+PE+ +G Y D+WS+G
Sbjct: 59 -LLKTWCGSPPYAAPELFEGKEYDGPKVDIWSLG 91
>BC109034-1|AAI09035.1| 737|Homo sapiens protein kinase C, epsilon
protein.
Length = 737
Score = 93.1 bits (221), Expect = 1e-18
Identities = 48/135 (35%), Positives = 79/135 (58%)
Frame = +2
Query: 323 KHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCH 502
KH L + +T R++ VMEY G L+ I++ + DE R R + ++ A+ + H
Sbjct: 465 KHPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLH 524
Query: 503 ERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILK 682
+ GV++RD+K +N+L+D + KL+DFG + + NGV + TFCG+ Y +PEIL+
Sbjct: 525 QHGVIYRDLKLDNILLDAEGHCKLADFGMCKEGI--LNGV--TTTTFCGTPDYIAPEILQ 580
Query: 683 GVPYRPQDSDVWSMG 727
+ Y P D W++G
Sbjct: 581 ELEYGP-SVDWWALG 594
>BC109033-1|AAI09034.1| 737|Homo sapiens protein kinase C, epsilon
protein.
Length = 737
Score = 93.1 bits (221), Expect = 1e-18
Identities = 48/135 (35%), Positives = 79/135 (58%)
Frame = +2
Query: 323 KHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCH 502
KH L + +T R++ VMEY G L+ I++ + DE R R + ++ A+ + H
Sbjct: 465 KHPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLH 524
Query: 503 ERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILK 682
+ GV++RD+K +N+L+D + KL+DFG + + NGV + TFCG+ Y +PEIL+
Sbjct: 525 QHGVIYRDLKLDNILLDAEGHCKLADFGMCKEGI--LNGV--TTTTFCGTPDYIAPEILQ 580
Query: 683 GVPYRPQDSDVWSMG 727
+ Y P D W++G
Sbjct: 581 ELEYGP-SVDWWALG 594
>U85755-1|AAD00575.1| 299|Homo sapiens serum-inducible kinase
protein.
Length = 299
Score = 92.3 bits (219), Expect = 2e-18
Identities = 46/162 (28%), Positives = 90/162 (55%)
Frame = +2
Query: 242 KIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDI 421
KII + + ++ + +EIE+ + L H+++++F E +YI++EY S+ I
Sbjct: 2 KIIPHSRVAKPHQREKIDKEIELHRILHHKHVVQFYHYFEDKENIYILLEYCSRRSMAHI 61
Query: 422 IRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGH 601
++ + + E R + +Q+V + Y HE+ ++HRD+K N ++ + +K+ DFG A
Sbjct: 62 LKARKVLTEPEVRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGDFGLA-AR 120
Query: 602 MKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
++P + T CG+ Y SPE+L + +SD+W++G
Sbjct: 121 LEP---LEHRRRTICGTPNYLSPEVLNKQGH-GCESDIWALG 158
>M95936-1|AAA58364.1| 481|Homo sapiens protein serine/threonine
kinase protein.
Length = 481
Score = 92.3 bits (219), Expect = 2e-18
Identities = 54/154 (35%), Positives = 86/154 (55%), Gaps = 3/154 (1%)
Frame = +2
Query: 299 EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQL 478
E V++ +H L A +T R+ VMEYA G L + +++ E R R + ++
Sbjct: 200 ESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEI 259
Query: 479 VEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYA 658
V A++Y H R VV+RDIK ENL++D +IK++DFG + + +G A +TFCG+
Sbjct: 260 VSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGI--SDG--ATMKTFCGTPE 315
Query: 659 YASPEILKGVPYRPQDSDVWSMG---SSIICHRL 751
Y +PE+L+ Y + D W +G ++C RL
Sbjct: 316 YLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRL 348
>M77198-1|AAA36585.1| 520|Homo sapiens rac protein kinase-beta
protein.
Length = 520
Score = 92.3 bits (219), Expect = 2e-18
Identities = 54/154 (35%), Positives = 86/154 (55%), Gaps = 3/154 (1%)
Frame = +2
Query: 299 EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQL 478
E V++ +H L A +T R+ VMEYA G L + +++ E R R + ++
Sbjct: 200 ESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEI 259
Query: 479 VEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYA 658
V A++Y H R VV+RDIK ENL++D +IK++DFG + + +G A +TFCG+
Sbjct: 260 VSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGI--SDG--ATMKTFCGTPE 315
Query: 659 YASPEILKGVPYRPQDSDVWSMG---SSIICHRL 751
Y +PE+L+ Y + D W +G ++C RL
Sbjct: 316 YLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRL 348
>BC120994-1|AAI20995.1| 481|Homo sapiens v-akt murine thymoma viral
oncogene homolog 2 protein.
Length = 481
Score = 92.3 bits (219), Expect = 2e-18
Identities = 54/154 (35%), Positives = 86/154 (55%), Gaps = 3/154 (1%)
Frame = +2
Query: 299 EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQL 478
E V++ +H L A +T R+ VMEYA G L + +++ E R R + ++
Sbjct: 200 ESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEI 259
Query: 479 VEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYA 658
V A++Y H R VV+RDIK ENL++D +IK++DFG + + +G A +TFCG+
Sbjct: 260 VSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGI--SDG--ATMKTFCGTPE 315
Query: 659 YASPEILKGVPYRPQDSDVWSMG---SSIICHRL 751
Y +PE+L+ Y + D W +G ++C RL
Sbjct: 316 YLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRL 348
>AB006972-1|BAB69958.1| 970|Homo sapiens Sak protein.
Length = 970
Score = 92.3 bits (219), Expect = 2e-18
Identities = 53/175 (30%), Positives = 89/175 (50%), Gaps = 1/175 (0%)
Frame = +2
Query: 206 ASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIV 385
A S +VAIK+I K + + + E+++ LKH +++ E ++ VY+V
Sbjct: 29 AESIHSGLEVAIKMIDKKAMYKAGMVQRVQNEVKIHCQLKHPSILELYNYFEDSNYVYLV 88
Query: 386 MEYAENGSLLDIIR-KDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGL 562
+E NG + ++ + + E R + Q++ + Y H G++HRD+ NLL+ +
Sbjct: 89 LEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLHSHGILHRDLTLSNLLLTRNM 148
Query: 563 NIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
NIK++DFG A P + T CG+ Y SPEI + +SDVWS+G
Sbjct: 149 NIKIADFGLATQLKMPHEKHY----TLCGTPNYISPEIATRSAH-GLESDVWSLG 198
>Y13115-1|CAA73575.1| 970|Homo sapiens serine/threonine protein
kinase protein.
Length = 970
Score = 91.9 bits (218), Expect = 2e-18
Identities = 53/175 (30%), Positives = 89/175 (50%), Gaps = 1/175 (0%)
Frame = +2
Query: 206 ASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIV 385
A S +VAIK+I K + + + E+++ LKH +++ E ++ VY+V
Sbjct: 29 AESIHTGLEVAIKMIDKKAMYKAGMVQRVKNEVKIHCQLKHPSILELYNYFEDSNYVYLV 88
Query: 386 MEYAENGSLLDIIR-KDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGL 562
+E NG + ++ + + E R + Q++ + Y H G++HRD+ NLL+ +
Sbjct: 89 LEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLHSHGILHRDLTLSNLLLTRNM 148
Query: 563 NIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
NIK++DFG A P + T CG+ Y SPEI + +SDVWS+G
Sbjct: 149 NIKIADFGLATQLKMPHEKHY----TLCGTPNYISPEIATRSAH-GLESDVWSLG 198
>BT020098-1|AAV38901.1| 367|Homo sapiens serum/glucocorticoid
regulated kinase 2 protein.
Length = 367
Score = 91.9 bits (218), Expect = 2e-18
Identities = 41/141 (29%), Positives = 83/141 (58%)
Frame = +2
Query: 308 VVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEA 487
++K ++H L+ + +T ++Y V++Y G L +++++ E R R + ++ A
Sbjct: 87 LLKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASA 146
Query: 488 VDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 667
+DY H +++RD+K EN+L+D ++ L+DFG + ++P++ + TFCG+ Y +
Sbjct: 147 IDYLHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPED----TTSTFCGTPEYLA 202
Query: 668 PEILKGVPYRPQDSDVWSMGS 730
PE+L+ PY + D W +G+
Sbjct: 203 PEVLRKEPY-DRAVDWWCLGA 222
>BC036023-1|AAH36023.1| 970|Homo sapiens polo-like kinase 4
(Drosophila) protein.
Length = 970
Score = 91.9 bits (218), Expect = 2e-18
Identities = 53/175 (30%), Positives = 89/175 (50%), Gaps = 1/175 (0%)
Frame = +2
Query: 206 ASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIV 385
A S +VAIK+I K + + + E+++ LKH +++ E ++ VY+V
Sbjct: 29 AESIHTGLEVAIKMIDKKAMYKAGMVQRVQNEVKIHCQLKHPSILELYNYFEDSNYVYLV 88
Query: 386 MEYAENGSLLDIIR-KDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGL 562
+E NG + ++ + + E R + Q++ + Y H G++HRD+ NLL+ +
Sbjct: 89 LEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLHSHGILHRDLTLSNLLLTRNM 148
Query: 563 NIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
NIK++DFG A P + T CG+ Y SPEI + +SDVWS+G
Sbjct: 149 NIKIADFGLATQLKMPHEKHY----TLCGTPNYISPEIATRSAH-GLESDVWSLG 198
>BC032709-1|AAH32709.1| 344|Homo sapiens AKT2 protein protein.
Length = 344
Score = 91.9 bits (218), Expect = 2e-18
Identities = 51/143 (35%), Positives = 81/143 (56%)
Frame = +2
Query: 299 EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQL 478
E V++ +H L A +T R+ VMEYA G L + +++ E R R + ++
Sbjct: 200 ESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEI 259
Query: 479 VEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYA 658
V A++Y H R VV+RDIK ENL++D +IK++DFG + + +G A +TFCG+
Sbjct: 260 VSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGI--SDG--ATMKTFCGTPE 315
Query: 659 YASPEILKGVPYRPQDSDVWSMG 727
Y +PE+L+ Y + D W +G
Sbjct: 316 YLAPEVLEDNDY-GRAVDWWGLG 337
>L33881-1|AAB17011.1| 587|Homo sapiens protein kinase C iota
protein.
Length = 587
Score = 91.1 bits (216), Expect = 4e-18
Identities = 49/165 (29%), Positives = 91/165 (55%), Gaps = 1/165 (0%)
Frame = +2
Query: 236 AIKIISKFQAPGDYLKKFLPREIEVVK-GLKHENLIRFLQAIETTHRVYIVMEYAENGSL 412
A+K++ K D ++ E V + H L+ +T R++ V+EY G L
Sbjct: 272 AMKVVKKELVNDDEDIDWVQTEKHVFEQASNHPFLVGLHSCFQTESRLFFVIEYVNGGDL 331
Query: 413 LDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 592
+ +++ + + E R + ++ A++Y HERG+++RD+K +N+L+D +IKL+D+G
Sbjct: 332 MFHMQRQRKLPEEHARFYSAEISLALNYLHERGIIYRDLKLDNVLLDSEGHIKLTDYGMC 391
Query: 593 RGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
+ ++P + + TFCG+ Y +PEIL+G Y D W++G
Sbjct: 392 KEGLRPGD----TTSTFCGTPNYIAPEILRGEDY-GFSVDWWALG 431
>L18964-1|AAA60171.1| 587|Homo sapiens protein kinase C iota
protein.
Length = 587
Score = 91.1 bits (216), Expect = 4e-18
Identities = 49/165 (29%), Positives = 91/165 (55%), Gaps = 1/165 (0%)
Frame = +2
Query: 236 AIKIISKFQAPGDYLKKFLPREIEVVK-GLKHENLIRFLQAIETTHRVYIVMEYAENGSL 412
A+K++ K D ++ E V + H L+ +T R++ V+EY G L
Sbjct: 272 AMKVVKKELVNDDEDIDWVQTEKHVFEQASNHPFLVGLHSCFQTESRLFFVIEYVNGGDL 331
Query: 413 LDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 592
+ +++ + + E R + ++ A++Y HERG+++RD+K +N+L+D +IKL+D+G
Sbjct: 332 MFHMQRQRKLPEEHARFYSAEISLALNYLHERGIIYRDLKLDNVLLDSEGHIKLTDYGMC 391
Query: 593 RGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
+ ++P + + TFCG+ Y +PEIL+G Y D W++G
Sbjct: 392 KEGLRPGD----TTSTFCGTPNYIAPEILRGEDY-GFSVDWWALG 431
>BC127622-1|AAI27623.1| 596|Homo sapiens myosin light chain kinase
2, skeletal muscle protein.
Length = 596
Score = 91.1 bits (216), Expect = 4e-18
Identities = 60/169 (35%), Positives = 93/169 (55%), Gaps = 3/169 (1%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
++A K+I K Q P D K+ + EIEV+ L H NLI+ AIET H + + MEY E G
Sbjct: 310 KLAAKVIKK-QTPKD--KEMVLLEIEVMNQLNHRNLIQLYAAIETPHEIVLFMEYIEGGE 366
Query: 410 LLD-IIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDH--GLNIKLSD 580
L + I+ +D H+ E + +Q+ + + + H+ V+H D+K EN+L + G +K+ D
Sbjct: 367 LFERIVDEDYHLTEVDTMVFVRQICDGILFMHKMRVLHLDLKPENILCVNTTGHLVKIID 426
Query: 581 FGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
FG AR + N L F G+ + SPE++ +D+WSMG
Sbjct: 427 FGLARRY----NPNEKLKVNF-GTPEFLSPEVV-NYDQISDKTDMWSMG 469
>BC092413-1|AAH92413.1| 596|Homo sapiens myosin light chain kinase
2, skeletal muscle protein.
Length = 596
Score = 91.1 bits (216), Expect = 4e-18
Identities = 60/169 (35%), Positives = 93/169 (55%), Gaps = 3/169 (1%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
++A K+I K Q P D K+ + EIEV+ L H NLI+ AIET H + + MEY E G
Sbjct: 310 KLAAKVIKK-QTPKD--KEMVLLEIEVMNQLNHRNLIQLYAAIETPHEIVLFMEYIEGGE 366
Query: 410 LLD-IIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDH--GLNIKLSD 580
L + I+ +D H+ E + +Q+ + + + H+ V+H D+K EN+L + G +K+ D
Sbjct: 367 LFERIVDEDYHLTEVDTMVFVRQICDGILFMHKMRVLHLDLKPENILCVNTTGHLVKIID 426
Query: 581 FGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
FG AR + N L F G+ + SPE++ +D+WSMG
Sbjct: 427 FGLARRY----NPNEKLKVNF-GTPEFLSPEVV-NYDQISDKTDMWSMG 469
>BC069627-1|AAH69627.1| 596|Homo sapiens skeletal myosin light
chain kinase protein.
Length = 596
Score = 91.1 bits (216), Expect = 4e-18
Identities = 60/169 (35%), Positives = 93/169 (55%), Gaps = 3/169 (1%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
++A K+I K Q P D K+ + EIEV+ L H NLI+ AIET H + + MEY E G
Sbjct: 310 KLAAKVIKK-QTPKD--KEMVLLEIEVMNQLNHRNLIQLYAAIETPHEIVLFMEYIEGGE 366
Query: 410 LLD-IIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDH--GLNIKLSD 580
L + I+ +D H+ E + +Q+ + + + H+ V+H D+K EN+L + G +K+ D
Sbjct: 367 LFERIVDEDYHLTEVDTMVFVRQICDGILFMHKMRVLHLDLKPENILCVNTTGHLVKIID 426
Query: 581 FGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
FG AR + N L F G+ + SPE++ +D+WSMG
Sbjct: 427 FGLARRY----NPNEKLKVNF-GTPEFLSPEVV-NYDQISDKTDMWSMG 469
>BC069613-1|AAH69613.1| 524|Homo sapiens p21-activated kinase 2
protein.
Length = 524
Score = 91.1 bits (216), Expect = 4e-18
Identities = 53/166 (31%), Positives = 96/166 (57%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
+VAIK I+ + P K+ + EI V+K LK+ N++ FL + +++VMEY GS
Sbjct: 274 EVAIKQINLQKQPK---KELIINEILVMKELKNPNIVNFLDSYLVGDELFVVMEYLAGGS 330
Query: 410 LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGF 589
L D++ + +DE + ++ ++A+++ H V+HRDIK +N+L+ ++KL+DFGF
Sbjct: 331 LTDVVT-ETCMDEAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGF 389
Query: 590 ARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
+ P+ + T G+ + +PE++ Y P+ D+WS+G
Sbjct: 390 C-AQITPEQ---SKRSTMVGTPYWMAPEVVTRKAYGPK-VDIWSLG 430
>BC022016-1|AAH22016.3| 587|Homo sapiens protein kinase C, iota
protein.
Length = 587
Score = 91.1 bits (216), Expect = 4e-18
Identities = 49/165 (29%), Positives = 91/165 (55%), Gaps = 1/165 (0%)
Frame = +2
Query: 236 AIKIISKFQAPGDYLKKFLPREIEVVK-GLKHENLIRFLQAIETTHRVYIVMEYAENGSL 412
A+K++ K D ++ E V + H L+ +T R++ V+EY G L
Sbjct: 272 AMKVVKKELVNDDEDIDWVQTEKHVFEQASNHPFLVGLHSCFQTESRLFFVIEYVNGGDL 331
Query: 413 LDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 592
+ +++ + + E R + ++ A++Y HERG+++RD+K +N+L+D +IKL+D+G
Sbjct: 332 MFHMQRQRKLPEEHARFYSAEISLALNYLHERGIIYRDLKLDNVLLDSEGHIKLTDYGMC 391
Query: 593 RGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
+ ++P + + TFCG+ Y +PEIL+G Y D W++G
Sbjct: 392 KEGLRPGD----TTSTFCGTPNYIAPEILRGEDY-GFSVDWWALG 431
>AY574904-1|AAT81413.1| 510|Homo sapiens regulated in COPD kinase
transcript variant 4 protein.
Length = 510
Score = 91.1 bits (216), Expect = 4e-18
Identities = 60/172 (34%), Positives = 96/172 (55%), Gaps = 3/172 (1%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
QVA+ +K A +Y K L E++++K LKH N++ +L + V I ME+ GS
Sbjct: 272 QVALDTSNKLAAEKEYRK--LQEEVDLLKALKHVNIVAYLGTCLQENTVSIFMEFVPGGS 329
Query: 410 LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCEN-LLMDHGLNIKLSDFG 586
+ II + + E ++ KQ+++ V Y HE VVHRDIK N +LM G+ IKL DFG
Sbjct: 330 ISSIINRFGPLPEMVFCKYTKQILQGVAYLHENCVVHRDIKGNNVMLMPTGI-IKLIDFG 388
Query: 587 FARG-HMKPKNGVFA-LSETFCGSYAYASPEILKGVPYRPQDSDVWSMGSSI 736
AR NG + + ++ G+ + +PE++ Y + SD+WS+G ++
Sbjct: 389 CARRLAWAGLNGTHSDMLKSMHGTPYWMAPEVINESGY-GRKSDIWSIGCTV 439
>AY574902-1|AAT81411.1| 1215|Homo sapiens regulated in COPD kinase
transcript variant 2 protein.
Length = 1215
Score = 91.1 bits (216), Expect = 4e-18
Identities = 60/172 (34%), Positives = 96/172 (55%), Gaps = 3/172 (1%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
QVA+ +K A +Y K L E++++K LKH N++ +L + V I ME+ GS
Sbjct: 977 QVALDTSNKLAAEKEYRK--LQEEVDLLKALKHVNIVAYLGTCLQENTVSIFMEFVPGGS 1034
Query: 410 LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCEN-LLMDHGLNIKLSDFG 586
+ II + + E ++ KQ+++ V Y HE VVHRDIK N +LM G+ IKL DFG
Sbjct: 1035 ISSIINRFGPLPEMVFCKYTKQILQGVAYLHENCVVHRDIKGNNVMLMPTGI-IKLIDFG 1093
Query: 587 FARG-HMKPKNGVFA-LSETFCGSYAYASPEILKGVPYRPQDSDVWSMGSSI 736
AR NG + + ++ G+ + +PE++ Y + SD+WS+G ++
Sbjct: 1094 CARRLAWAGLNGTHSDMLKSMHGTPYWMAPEVINESGY-GRKSDIWSIGCTV 1144
>AY574901-1|AAT81410.1| 1328|Homo sapiens regulated in COPD kinase
transcript variant 1 protein.
Length = 1328
Score = 91.1 bits (216), Expect = 4e-18
Identities = 60/172 (34%), Positives = 96/172 (55%), Gaps = 3/172 (1%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
QVA+ +K A +Y K L E++++K LKH N++ +L + V I ME+ GS
Sbjct: 1090 QVALDTSNKLAAEKEYRK--LQEEVDLLKALKHVNIVAYLGTCLQENTVSIFMEFVPGGS 1147
Query: 410 LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCEN-LLMDHGLNIKLSDFG 586
+ II + + E ++ KQ+++ V Y HE VVHRDIK N +LM G+ IKL DFG
Sbjct: 1148 ISSIINRFGPLPEMVFCKYTKQILQGVAYLHENCVVHRDIKGNNVMLMPTGI-IKLIDFG 1206
Query: 587 FARG-HMKPKNGVFA-LSETFCGSYAYASPEILKGVPYRPQDSDVWSMGSSI 736
AR NG + + ++ G+ + +PE++ Y + SD+WS+G ++
Sbjct: 1207 CARRLAWAGLNGTHSDMLKSMHGTPYWMAPEVINESGY-GRKSDIWSIGCTV 1257
>AL160175-10|CAC10006.1| 596|Homo sapiens myosin light chain kinase
2, skeletal muscle protein.
Length = 596
Score = 91.1 bits (216), Expect = 4e-18
Identities = 60/169 (35%), Positives = 93/169 (55%), Gaps = 3/169 (1%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
++A K+I K Q P D K+ + EIEV+ L H NLI+ AIET H + + MEY E G
Sbjct: 310 KLAAKVIKK-QTPKD--KEMVLLEIEVMNQLNHRNLIQLYAAIETPHEIVLFMEYIEGGE 366
Query: 410 LLD-IIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDH--GLNIKLSD 580
L + I+ +D H+ E + +Q+ + + + H+ V+H D+K EN+L + G +K+ D
Sbjct: 367 LFERIVDEDYHLTEVDTMVFVRQICDGILFMHKMRVLHLDLKPENILCVNTTGHLVKIID 426
Query: 581 FGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
FG AR + N L F G+ + SPE++ +D+WSMG
Sbjct: 427 FGLARRY----NPNEKLKVNF-GTPEFLSPEVV-NYDQISDKTDMWSMG 469
>AJ272502-1|CAC81354.1| 596|Homo sapiens skeletal muscle-specific
myosin light chain kinase protein.
Length = 596
Score = 91.1 bits (216), Expect = 4e-18
Identities = 60/169 (35%), Positives = 93/169 (55%), Gaps = 3/169 (1%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
++A K+I K Q P D K+ + EIEV+ L H NLI+ AIET H + + MEY E G
Sbjct: 310 KLAAKVIKK-QTPKD--KEMVLLEIEVMNQLNHRNLIQLYAAIETPHEIVLFMEYIEGGE 366
Query: 410 LLD-IIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDH--GLNIKLSD 580
L + I+ +D H+ E + +Q+ + + + H+ V+H D+K EN+L + G +K+ D
Sbjct: 367 LFERIVDEDYHLTEVDTMVFVRQICDGILFMHKMRVLHLDLKPENILCVNTTGHLVKIID 426
Query: 581 FGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
FG AR + N L F G+ + SPE++ +D+WSMG
Sbjct: 427 FGLARRY----NPNEKLKVNF-GTPEFLSPEVV-NYDQISDKTDMWSMG 469
>AF325549-1|AAK15494.1| 596|Homo sapiens skeletal myosin light
chain kinase protein.
Length = 596
Score = 91.1 bits (216), Expect = 4e-18
Identities = 60/169 (35%), Positives = 93/169 (55%), Gaps = 3/169 (1%)
Frame = +2
Query: 230 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 409
++A K+I K Q P D K+ + EIEV+ L H NLI+ AIET H + + MEY E G
Sbjct: 310 KLAAKVIKK-QTPKD--KEMVLLEIEVMNQLNHRNLIQLYAAIETPHEIVLFMEYIEGGE 366
Query: 410 LLD-IIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDH--GLNIKLSD 580
L + I+ +D H+ E + +Q+ + + + H+ V+H D+K EN+L + G +K+ D
Sbjct: 367 LFERIVDEDYHLTEVDTMVFVRQICDGILFMHKMRVLHLDLKPENILCVNTTGHLVKIID 426
Query: 581 FGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 727
FG AR + N L F G+ + SPE++ +D+WSMG
Sbjct: 427 FGLARRY----NPNEKLKVNF-GTPEFLSPEVV-NYDQISDKTDMWSMG 469
>X61037-1|CAA43372.1| 417|Homo sapiens human protein kinase B
protein.
Length = 417
Score = 90.6 bits (215), Expect = 5e-18
Identities = 55/155 (35%), Positives = 88/155 (56%), Gaps = 4/155 (2%)
Frame = +2
Query: 299 EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQL 478
E V + +H L R + +T R+ VMEYA G L + +++ E R R + ++
Sbjct: 135 ENRVQQNSRHPFLTRLKYSFQTHDRLCFVMEYANGGELFFHLSRERVFAEDRARFYGAEI 194
Query: 479 VEAVDYCH-ERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 655
V A+DY H E+ VV+RD+K ENL++D +IK++DFG + + K+G A +TFCG+
Sbjct: 195 VSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGI--KDG--ATMKTFCGTP 250
Query: 656 AYASPEILKGVPYRPQDSDVWSMG---SSIICHRL 751
Y +PE+L+ Y + D W +G ++C RL
Sbjct: 251 EYLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRL 284
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 103,499,100
Number of Sequences: 237096
Number of extensions: 2087679
Number of successful extensions: 8989
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 6509
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7076
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9144232952
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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