Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmte4m02
(719 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q9SN86 Cluster: Malate dehydrogenase, chloroplast precu... 123 4e-27
UniRef50_Q42972 Cluster: Malate dehydrogenase, glyoxysomal precu... 123 5e-27
UniRef50_P08249 Cluster: Malate dehydrogenase, mitochondrial pre... 120 3e-26
UniRef50_P40926 Cluster: Malate dehydrogenase, mitochondrial pre... 120 5e-26
UniRef50_Q9VU29 Cluster: Malate dehydrogenase; n=5; Protostomia|... 118 1e-25
UniRef50_Q9VU28 Cluster: Malate dehydrogenase; n=3; Sophophora|R... 114 2e-24
UniRef50_Q6BM17 Cluster: Malate dehydrogenase; n=4; Eukaryota|Re... 107 4e-22
UniRef50_UPI0000D571DB Cluster: PREDICTED: similar to CG7998-PA;... 105 8e-22
UniRef50_A2QMH9 Cluster: Malate dehydrogenase; n=7; Fungi/Metazo... 105 1e-21
UniRef50_A7TL95 Cluster: Putative uncharacterized protein; n=1; ... 100 4e-20
UniRef50_Q4Q3J3 Cluster: Malate dehydrogenase, putative; n=3; Le... 99 1e-19
UniRef50_Q9Y7R8 Cluster: Malate dehydrogenase; n=13; Dikarya|Rep... 97 4e-19
UniRef50_Q6FL22 Cluster: Malate dehydrogenase; n=1; Candida glab... 93 5e-18
UniRef50_P32419 Cluster: Malate dehydrogenase, peroxisomal; n=24... 93 5e-18
UniRef50_A7SQS1 Cluster: Predicted protein; n=1; Nematostella ve... 90 6e-17
UniRef50_Q6CP51 Cluster: Similar to sp|P22133 Saccharomyces cere... 84 3e-15
UniRef50_A7TSF5 Cluster: Putative uncharacterized protein; n=1; ... 83 9e-15
UniRef50_P22133 Cluster: Malate dehydrogenase, cytoplasmic; n=3;... 81 2e-14
UniRef50_UPI0000DB76D8 Cluster: PREDICTED: similar to CG7998-PA;... 79 1e-13
UniRef50_Q5ENS5 Cluster: Malate dehydrogenase; n=1; Heterocapsa ... 79 1e-13
UniRef50_A3BMG8 Cluster: Putative uncharacterized protein; n=3; ... 75 2e-12
UniRef50_Q4QDF0 Cluster: Glycosomal malate dehydrogenase; n=9; T... 75 2e-12
UniRef50_UPI0000D55CD8 Cluster: PREDICTED: similar to Malate DeH... 75 2e-12
UniRef50_Q75AT4 Cluster: ADL164Cp; n=2; Saccharomycetales|Rep: A... 73 5e-12
UniRef50_UPI00005A0834 Cluster: PREDICTED: similar to Malate deh... 73 7e-12
UniRef50_Q4Q3J5 Cluster: Malate dehydrogenase, putative; n=5; Tr... 71 2e-11
UniRef50_O26290 Cluster: Malate dehydrogenase; n=2; Methanobacte... 67 5e-10
UniRef50_A7I5J9 Cluster: L-lactate dehydrogenase precursor; n=1;... 66 6e-10
UniRef50_A2SSY4 Cluster: L-lactate dehydrogenase; n=3; Methanomi... 66 8e-10
UniRef50_P16115 Cluster: L-lactate dehydrogenase; n=4; Thermotog... 64 4e-09
UniRef50_Q6VVP7 Cluster: Malate dehydrogenase; n=6; Plasmodium|R... 63 6e-09
UniRef50_Q8TWG5 Cluster: Malate dehydrogenase; n=2; Euryarchaeot... 63 6e-09
UniRef50_Q86S07 Cluster: NAD-specific malate dehydrogenase 2; n=... 62 1e-08
UniRef50_Q86DP2 Cluster: Malate dehydrogenase; n=11; Fungi/Metaz... 62 1e-08
UniRef50_Q3J7E7 Cluster: Malate dehydrogenase; n=5; Gammaproteob... 62 1e-08
UniRef50_Q979N9 Cluster: Malate dehydrogenase; n=4; Thermoplasma... 61 3e-08
UniRef50_P22988 Cluster: L-lactate dehydrogenase A; n=19; Magnol... 61 3e-08
UniRef50_Q017A6 Cluster: Malate dehydrogenase; n=2; cellular org... 60 7e-08
UniRef50_Q8ZVB2 Cluster: Malate dehydrogenase; n=14; Thermoprote... 60 7e-08
UniRef50_A7GYI6 Cluster: Lactate/malate dehydrogenase, NAD bindi... 59 1e-07
UniRef50_A7DRG3 Cluster: Lactate/malate dehydrogenase; n=1; Cand... 58 2e-07
UniRef50_Q7VFV4 Cluster: Malate dehydrogenase; n=1; Helicobacter... 57 4e-07
UniRef50_Q64P62 Cluster: Malate dehydrogenase; n=28; Bacteroidet... 56 7e-07
UniRef50_A0RXX8 Cluster: Malate/L-lactate dehydrogenase; n=1; Ce... 56 1e-06
UniRef50_UPI0000D56DC5 Cluster: PREDICTED: similar to Malate deh... 55 2e-06
UniRef50_Q9PHY2 Cluster: Probable malate dehydrogenase; n=12; Ca... 54 3e-06
UniRef50_Q8YJE7 Cluster: Malate dehydrogenase; n=98; Bacteria|Re... 54 3e-06
UniRef50_O67655 Cluster: Malate dehydrogenase 1; n=3; Bacteria|R... 54 3e-06
UniRef50_A7U552 Cluster: Mitochondrial malate-dehydrogenase; n=2... 54 4e-06
UniRef50_P59390 Cluster: L-lactate dehydrogenase 2; n=8; Lactoba... 54 4e-06
UniRef50_UPI00015B5ACF Cluster: PREDICTED: similar to ENSANGP000... 54 5e-06
UniRef50_Q7M9A7 Cluster: Malate dehydrogenase; n=4; Epsilonprote... 54 5e-06
UniRef50_P11386 Cluster: Malate dehydrogenase; n=6; Sulfolobacea... 54 5e-06
UniRef50_A4L2P0 Cluster: L-lactate dehydrogenase; n=4; Lactobaci... 53 6e-06
UniRef50_Q18WQ6 Cluster: Malate dehydrogenase, NAD-dependent; n=... 53 8e-06
UniRef50_A1U9V0 Cluster: Lactate/malate dehydrogenase; n=6; Acti... 53 8e-06
UniRef50_Q6LZI3 Cluster: Malate dehydrogenase; n=5; Methanococcu... 53 8e-06
UniRef50_Q892U0 Cluster: L-lactate dehydrogenase; n=12; Bacteria... 53 8e-06
UniRef50_Q5CYZ2 Cluster: Lactate dehydrogenase, adjacent gene en... 52 1e-05
UniRef50_Q7NHJ3 Cluster: Malate dehydrogenase; n=13; cellular or... 52 1e-05
UniRef50_A5KJY5 Cluster: Putative uncharacterized protein; n=2; ... 52 1e-05
UniRef50_UPI00015B4591 Cluster: PREDICTED: similar to mitochondr... 51 2e-05
UniRef50_Q1IRL5 Cluster: L-lactate dehydrogenase; n=6; Bacteria|... 51 3e-05
UniRef50_A4A2L6 Cluster: L-lactate dehydrogenase; n=4; Bacteria|... 51 3e-05
UniRef50_A6Q7S2 Cluster: Malate dehydrogenase, NAD-dependent; n=... 50 6e-05
UniRef50_O51114 Cluster: L-lactate dehydrogenase; n=4; Borrelia ... 50 6e-05
UniRef50_Q5LXE1 Cluster: Malate dehydrogenase; n=115; cellular o... 49 1e-04
UniRef50_Q07841 Cluster: Malate dehydrogenase; n=7; Halobacteria... 49 1e-04
UniRef50_Q9P7P7 Cluster: Probable L-lactate dehydrogenase; n=2; ... 49 1e-04
UniRef50_Q03BE6 Cluster: L-lactate dehydrogenase; n=1; Lactobaci... 48 2e-04
UniRef50_A3EWH3 Cluster: Malate/lactate dehydrogenase; n=1; Lept... 48 2e-04
UniRef50_Q8XP62 Cluster: L-lactate dehydrogenase; n=11; Clostrid... 48 2e-04
UniRef50_Q6A9C3 Cluster: L-lactate dehydrogenase; n=2; Propionib... 48 2e-04
UniRef50_Q7UY63 Cluster: L-lactate/malate dehydrogenase; n=2; Pl... 47 4e-04
UniRef50_Q6F0L9 Cluster: L-lactate dehydrogenase; n=6; Mollicute... 47 5e-04
UniRef50_O08349 Cluster: Malate dehydrogenase; n=1; Archaeoglobu... 46 0.001
UniRef50_O67581 Cluster: Malate dehydrogenase 2; n=1; Aquifex ae... 46 0.001
UniRef50_Q6KIP9 Cluster: L-lactate dehydrogenase; n=1; Mycoplasm... 46 0.001
UniRef50_Q4Q7X6 Cluster: Cytosolic malate dehydrogenase, putativ... 45 0.002
UniRef50_Q3ZZJ7 Cluster: Malate dehydrogenase; n=5; cellular org... 45 0.002
UniRef50_A0LRV1 Cluster: Lactate/malate dehydrogenase; n=3; Acti... 45 0.002
UniRef50_Q838C9 Cluster: L-lactate dehydrogenase 2; n=9; Bacilli... 45 0.002
UniRef50_Q7MTK2 Cluster: Malate dehydrogenase; n=4; Bacteroidale... 44 0.004
UniRef50_P0A3M9 Cluster: L-lactate dehydrogenase; n=140; Bacteri... 44 0.005
UniRef50_P19869 Cluster: L-lactate dehydrogenase 2; n=17; Bacter... 43 0.007
UniRef50_Q81K80 Cluster: L-lactate dehydrogenase 2; n=12; Firmic... 43 0.007
UniRef50_A1HSK3 Cluster: Lactate/malate dehydrogenase; n=1; Ther... 43 0.009
UniRef50_Q98PG4 Cluster: L-lactate dehydrogenase; n=1; Mycoplasm... 43 0.009
UniRef50_Q64YY6 Cluster: Malate dehydrogenase; n=5; Bacteroidale... 41 0.027
UniRef50_P50933 Cluster: L-lactate dehydrogenase; n=7; Bacteria|... 41 0.027
UniRef50_A2G340 Cluster: Malate dehydrogenase; n=18; Trichomonad... 41 0.035
UniRef50_Q4J9W2 Cluster: Putative uncharacterized protein; n=1; ... 41 0.035
UniRef50_P20619 Cluster: L-lactate dehydrogenase X; n=14; Bacill... 41 0.035
UniRef50_UPI00015BB1FC Cluster: malate dehydrogenase (NAD); n=1;... 40 0.047
UniRef50_A2SNY0 Cluster: Malate/lactate dehydrogenases-like prot... 40 0.062
UniRef50_Q9GSY3 Cluster: Malate dehydrogenase; n=1; Hypotrichomo... 40 0.082
UniRef50_Q4A0K7 Cluster: Lactate dehydrogenase; n=1; Staphylococ... 39 0.11
UniRef50_Q23CW4 Cluster: Malate dehydrogenase, cytoplasmic, puta... 39 0.11
UniRef50_Q1FID3 Cluster: L-lactate dehydrogenase precursor; n=1;... 39 0.14
UniRef50_Q81XJ7 Cluster: L-lactate dehydrogenase 3; n=13; Firmic... 39 0.14
UniRef50_Q8IE66 Cluster: Oxidoreductase, putative; n=6; Plasmodi... 38 0.25
UniRef50_A3DCA4 Cluster: L-lactate dehydrogenase precursor; n=2;... 38 0.33
UniRef50_P62051 Cluster: L-lactate dehydrogenase; n=2; Desulfovi... 38 0.33
UniRef50_Q6A6E3 Cluster: L-lactate dehydrogenase; n=1; Propionib... 37 0.44
UniRef50_Q9KGT7 Cluster: Restriction endonuclease Hpy8I; n=5; He... 37 0.44
UniRef50_P0C0J4 Cluster: L-lactate dehydrogenase; n=5; Mycoplasm... 37 0.44
UniRef50_Q9EVR0 Cluster: L-lactate dehydrogenase; n=1; Selenomon... 37 0.58
UniRef50_Q4CTT8 Cluster: Putative uncharacterized protein; n=1; ... 36 1.3
UniRef50_A5Z9B1 Cluster: Putative uncharacterized protein; n=1; ... 35 1.8
UniRef50_A5IYS9 Cluster: L-lactate dehydrogenase; n=2; Mycoplasm... 35 1.8
UniRef50_Q4UJ29 Cluster: L-lactate dehydrogenase, putative; n=2;... 35 1.8
UniRef50_Q22N17 Cluster: Putative uncharacterized protein; n=1; ... 35 1.8
UniRef50_Q9GPV2 Cluster: Cytosolic malate dehydrogenase; n=4; Tr... 34 3.1
UniRef50_A3JXA9 Cluster: L-lactate dehydrogenase; n=1; Sagittula... 34 4.1
UniRef50_A1ZW20 Cluster: Putative uncharacterized protein; n=1; ... 34 4.1
UniRef50_Q27743 Cluster: L-lactate dehydrogenase; n=17; Apicompl... 33 5.4
UniRef50_Q8EYA2 Cluster: Putative uncharacterized protein; n=4; ... 33 9.4
UniRef50_Q4JY42 Cluster: L-lactate dehydrogenase; n=1; Corynebac... 33 9.4
>UniRef50_Q9SN86 Cluster: Malate dehydrogenase, chloroplast
precursor; n=41; cellular organisms|Rep: Malate
dehydrogenase, chloroplast precursor - Arabidopsis
thaliana (Mouse-ear cress)
Length = 403
Score = 123 bits (297), Expect = 4e-27
Identities = 61/159 (38%), Positives = 98/159 (61%)
Frame = +2
Query: 221 QVSVIGAASDIGSYVSLFLKRNSKVSKLHLYDDDDRIKGTELELSNLPGGPSVSAFIGDT 400
+V+V+GAA IG +SL +K + VS LHLYD + +KG +LS+ V F G +
Sbjct: 84 KVAVLGAAGGIGQPLSLLIKMSPLVSTLHLYDIAN-VKGVAADLSHCNTPSQVRDFTGPS 142
Query: 401 NLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAISTNPI 580
L + N+VV+ + +PRKPG TR+ + NA +++ L +A+A AF+ I +NP+
Sbjct: 143 ELADCLKDVNVVVIPAGVPRKPGMTRDDLFNINANIVKTLVEAVAENCPNAFIHIISNPV 202
Query: 581 NYLIPFASTVMYKYGCYNPSKMFGITHIDTSRSRSFVAK 697
N +P A+ V+ K G Y+P K+FG+T +D R+ +FV++
Sbjct: 203 NSTVPIAAEVLKKKGVYDPKKLFGVTTLDVVRANTFVSQ 241
>UniRef50_Q42972 Cluster: Malate dehydrogenase, glyoxysomal
precursor; n=11; Eukaryota|Rep: Malate dehydrogenase,
glyoxysomal precursor - Oryza sativa subsp. japonica
(Rice)
Length = 356
Score = 123 bits (296), Expect = 5e-27
Identities = 59/164 (35%), Positives = 100/164 (60%)
Frame = +2
Query: 221 QVSVIGAASDIGSYVSLFLKRNSKVSKLHLYDDDDRIKGTELELSNLPGGPSVSAFIGDT 400
+V+++GA+ IG ++L +K N VS LHLYD + G ++S++ G V F+G
Sbjct: 46 KVAILGASGGIGQPLALLMKMNPLVSVLHLYDVVNT-PGVTADISHMNTGAVVRGFLGQP 104
Query: 401 NLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAISTNPI 580
LE A+ +LV++ + +PRKPG TR+ + NA +++ LC+ IA A V + +NP+
Sbjct: 105 QLENALTGMDLVIIPAGVPRKPGMTRDDLFNINAGIVRTLCEGIAKCCPNAIVNVISNPV 164
Query: 581 NYLIPFASTVMYKYGCYNPSKMFGITHIDTSRSRSFVAKALKIN 712
N +P A+ V K G Y+P ++ G+T +D R+ +FVA+ L ++
Sbjct: 165 NSTVPIAAEVFKKAGTYDPKRLLGVTTLDVVRANTFVAEVLGLD 208
>UniRef50_P08249 Cluster: Malate dehydrogenase, mitochondrial
precursor; n=514; cellular organisms|Rep: Malate
dehydrogenase, mitochondrial precursor - Mus musculus
(Mouse)
Length = 338
Score = 120 bits (290), Expect = 3e-26
Identities = 62/172 (36%), Positives = 99/172 (57%)
Frame = +2
Query: 182 LKKNTLILQKRNVQVSVIGAASDIGSYVSLFLKRNSKVSKLHLYDDDDRIKGTELELSNL 361
L+++ + N +V+V+GA+ IG +SL LK + VS+L LYD G +LS++
Sbjct: 13 LRRSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIA-HTPGVAADLSHI 71
Query: 362 PGGPSVSAFIGDTNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQ 541
+V ++G L + ++VV+ + +PRKPG TR+ + NA ++ L A A
Sbjct: 72 ETRANVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQH 131
Query: 542 NQEAFVAISTNPINYLIPFASTVMYKYGCYNPSKMFGITHIDTSRSRSFVAK 697
EA V I NP+N IP + V K+G YNP+K+FG+T +D R+ +FVA+
Sbjct: 132 CPEAMVCIIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTFVAE 183
>UniRef50_P40926 Cluster: Malate dehydrogenase, mitochondrial
precursor; n=119; cellular organisms|Rep: Malate
dehydrogenase, mitochondrial precursor - Homo sapiens
(Human)
Length = 338
Score = 120 bits (288), Expect = 5e-26
Identities = 60/172 (34%), Positives = 99/172 (57%)
Frame = +2
Query: 182 LKKNTLILQKRNVQVSVIGAASDIGSYVSLFLKRNSKVSKLHLYDDDDRIKGTELELSNL 361
L+++ + N +V+V+GA+ IG +SL LK + VS+L LYD G +LS++
Sbjct: 13 LRRSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIA-HTPGVAADLSHI 71
Query: 362 PGGPSVSAFIGDTNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQ 541
+V ++G L + ++VV+ + +PRKPG TR+ + NA ++ L A A
Sbjct: 72 ETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQH 131
Query: 542 NQEAFVAISTNPINYLIPFASTVMYKYGCYNPSKMFGITHIDTSRSRSFVAK 697
EA + + NP+N IP + V K+G YNP+K+FG+T +D R+ +FVA+
Sbjct: 132 CPEAMICVIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTFVAE 183
>UniRef50_Q9VU29 Cluster: Malate dehydrogenase; n=5;
Protostomia|Rep: Malate dehydrogenase - Drosophila
melanogaster (Fruit fly)
Length = 347
Score = 118 bits (284), Expect = 1e-25
Identities = 59/169 (34%), Positives = 103/169 (60%)
Frame = +2
Query: 212 RNVQVSVIGAASDIGSYVSLFLKRNSKVSKLHLYDDDDRIKGTELELSNLPGGPSVSAFI 391
R ++V+V+G+ IG +SL LK N ++S L LYD + G ++LS++ SV F
Sbjct: 26 RGLKVAVVGSVGGIGQPLSLLLKHNPQISTLSLYDIKNTT-GVGVDLSHINTRASVCPFE 84
Query: 392 GDTNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAIST 571
G L++A+ +++VV+ + +PRKPG RE ++ NA + + A + A +A T
Sbjct: 85 GKNGLKKAMDKADIVVIPAGLPRKPGMKREDLVDVNASVACEVAFAASEVCPGAMLAFIT 144
Query: 572 NPINYLIPFASTVMYKYGCYNPSKMFGITHIDTSRSRSFVAKALKINAQ 718
NPIN ++P +T++ G Y+P+++FG+T +D R+++FVA L ++ Q
Sbjct: 145 NPINVIVPIVATILKAKGTYDPNRLFGVTTLDVVRAQTFVADILNVDPQ 193
>UniRef50_Q9VU28 Cluster: Malate dehydrogenase; n=3; Sophophora|Rep:
Malate dehydrogenase - Drosophila melanogaster (Fruit
fly)
Length = 349
Score = 114 bits (274), Expect = 2e-24
Identities = 55/167 (32%), Positives = 101/167 (60%)
Frame = +2
Query: 212 RNVQVSVIGAASDIGSYVSLFLKRNSKVSKLHLYDDDDRIKGTELELSNLPGGPSVSAFI 391
R ++V+V+GA IG +SL L+R + +L L+D + +KG +LS++ V F
Sbjct: 21 RTLKVAVVGAGGGIGQPLSLLLRRCPGIDELALHDLSE-MKGIATDLSHISQTGKVIGFT 79
Query: 392 GDTNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAIST 571
G+ LE A+ +++VV+ + MPR PG R+ ++ AN + ++ AI+ + A +A T
Sbjct: 80 GEKELESAVSGADVVVVAAGMPRLPGMQRDHLMAANGNVAVKVATAISNASPRAHLAFIT 139
Query: 572 NPINYLIPFASTVMYKYGCYNPSKMFGITHIDTSRSRSFVAKALKIN 712
NP+N ++P A+ V+ +G ++ ++FGIT +D RS+ F+ ++ I+
Sbjct: 140 NPVNMIVPAAAEVLMAHGTFDSRRLFGITTLDVVRSKKFIGDSMNIS 186
>UniRef50_Q6BM17 Cluster: Malate dehydrogenase; n=4; Eukaryota|Rep:
Malate dehydrogenase - Debaryomyces hansenii (Yeast)
(Torulaspora hansenii)
Length = 346
Score = 107 bits (256), Expect = 4e-22
Identities = 58/168 (34%), Positives = 101/168 (60%), Gaps = 5/168 (2%)
Frame = +2
Query: 218 VQVSVIGAASDIGSYVSLFLKRNSKVSKLHLYDDDDRIKGTELELSNLPGGPSVSAFIGD 397
V+V+V GAA IG +SL LK N +VS+L L+D + G +LS++ V+ +
Sbjct: 2 VKVTVCGAAGGIGQPLSLLLKLNPQVSELSLFDVVNA-NGVAADLSHICSPAKVTGYQPS 60
Query: 398 TN-----LEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVA 562
+ +++A+ +S+LVV+ + +PRKPG TR + NA +I+ + +I A +
Sbjct: 61 SKEDRDTIQKALVNSDLVVIPAGVPRKPGMTRADLFNINASIIRDIVGSIGKACPNAAIL 120
Query: 563 ISTNPINYLIPFASTVMYKYGCYNPSKMFGITHIDTSRSRSFVAKALK 706
I +NP+N +P A+ V+ K G +NP K+FG+T +D+ R+ +F+ + +K
Sbjct: 121 IISNPVNSTVPIAAEVLKKLGVFNPKKLFGVTTLDSVRAETFLGELIK 168
>UniRef50_UPI0000D571DB Cluster: PREDICTED: similar to CG7998-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG7998-PA - Tribolium castaneum
Length = 376
Score = 105 bits (253), Expect = 8e-22
Identities = 54/167 (32%), Positives = 98/167 (58%)
Frame = +2
Query: 218 VQVSVIGAASDIGSYVSLFLKRNSKVSKLHLYDDDDRIKGTELELSNLPGGPSVSAFIGD 397
++V+++GA + G VSL LK++ + +L LYD ++G +L+ + V++F G+
Sbjct: 29 MKVTILGAGGNTGKSVSLMLKQSPFIDELCLYDTQS-LEGFANDLNYVDTKCRVTSFFGN 87
Query: 398 TNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAISTNP 577
++++A+ SN++V++S + NAP+++ L +IA + ++ VAI P
Sbjct: 88 KDIQKALTKSNIIVVLSCCHAAEPTNYASLFDRNAPIVKDLATSIAKFSPKSTVAIGVEP 147
Query: 578 INYLIPFASTVMYKYGCYNPSKMFGITHIDTSRSRSFVAKALKINAQ 718
IN ++P S +M KYG YNP +FGIT +D R+ FVA+ L + +
Sbjct: 148 INSVVPMFSEIMKKYGHYNPYSIFGITTVDVVRTNKFVAEILGLEPE 194
>UniRef50_A2QMH9 Cluster: Malate dehydrogenase; n=7; Fungi/Metazoa
group|Rep: Malate dehydrogenase - Aspergillus niger
Length = 340
Score = 105 bits (251), Expect = 1e-21
Identities = 54/165 (32%), Positives = 93/165 (56%), Gaps = 1/165 (0%)
Frame = +2
Query: 221 QVSVIGAASDIGSYVSLFLKRNSKVSKLHLYDDDDRIKGTELELSNLPGGPSVSAFIGD- 397
+V+V+GAA IG +SL +K+N V+ L LYD G ++S++ +V +
Sbjct: 25 KVAVLGAAGGIGQPLSLLMKQNPLVTDLALYDIRGG-PGVAADISHINTNSTVKGYEPTP 83
Query: 398 TNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAISTNP 577
+ L A+ S ++++ + +PRKPG TR+ + NA +++ L KA A EA + + +NP
Sbjct: 84 SGLRDALKGSEIILIPAGVPRKPGMTRDDLFNTNASIVRDLAKAAAEAAPEANILVISNP 143
Query: 578 INYLIPFASTVMYKYGCYNPSKMFGITHIDTSRSRSFVAKALKIN 712
+N +P S V G YNP ++FG+T +D R+ F+++ N
Sbjct: 144 VNSTVPIVSEVYKSKGVYNPKRLFGVTTLDVVRASRFISQVKGTN 188
>UniRef50_A7TL95 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 365
Score = 100 bits (239), Expect = 4e-20
Identities = 58/159 (36%), Positives = 86/159 (54%), Gaps = 1/159 (0%)
Frame = +2
Query: 218 VQVSVIGAASDIGSYVSLFLKRNSKVSKLHLYDDDDRIKGTELELSNLPGGPSVSAFIGD 397
V+V V+GA+ IG +SL LK N VS L LYD D G +LS++ + D
Sbjct: 2 VKVCVLGASGGIGQPLSLLLKLNPYVSDLALYDISDITAGVAKDLSHINTNSDSEGYNKD 61
Query: 398 TNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRL-CKAIAAQNQEAFVAISTN 574
+ + + S LV++ + +PRKPG TR+ + NA +IQ L K + I +N
Sbjct: 62 EDFKNLLEGSELVIVTAGIPRKPGMTRDDLFKINAKIIQNLTVKYAKFAPVHCKLLIISN 121
Query: 575 PINYLIPFASTVMYKYGCYNPSKMFGITHIDTSRSRSFV 691
P+N LIP + G NPS++FGIT +D RS++F+
Sbjct: 122 PVNSLIPVVIETLKINGRLNPSQVFGITMLDIIRSQTFL 160
>UniRef50_Q4Q3J3 Cluster: Malate dehydrogenase, putative; n=3;
Leishmania|Rep: Malate dehydrogenase, putative -
Leishmania major
Length = 331
Score = 98.7 bits (235), Expect = 1e-19
Identities = 51/157 (32%), Positives = 94/157 (59%)
Frame = +2
Query: 221 QVSVIGAASDIGSYVSLFLKRNSKVSKLHLYDDDDRIKGTELELSNLPGGPSVSAFIGDT 400
+V+V+GA+ IG ++L L +N +VS+L LYD +G ++LS+ P V+ +
Sbjct: 10 KVTVLGASGAIGQPLALALVQNKRVSELALYDIVQP-RGVAVDLSHFPRKVKVTGYPTKW 68
Query: 401 NLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAISTNPI 580
+ +A+ ++LV+M + MPR+PG T + + NA + L A+A ++ +AI +NP+
Sbjct: 69 -IHKALDGADLVLMSAGMPRRPGMTHDDLFNTNALTVNELSAAVARYAPKSVLAIISNPL 127
Query: 581 NYLIPFASTVMYKYGCYNPSKMFGITHIDTSRSRSFV 691
N ++P A+ + + G Y+P K+FGI ++ R+R +
Sbjct: 128 NSMVPVAAETLQRAGVYDPRKLFGIISLNMMRARKML 164
>UniRef50_Q9Y7R8 Cluster: Malate dehydrogenase; n=13; Dikarya|Rep:
Malate dehydrogenase - Schizosaccharomyces pombe
(Fission yeast)
Length = 341
Score = 97.1 bits (231), Expect = 4e-19
Identities = 51/170 (30%), Positives = 93/170 (54%), Gaps = 1/170 (0%)
Frame = +2
Query: 212 RNVQVSVIGAASDIGSYVSLFLKRNSKVSKLHLYDDDDRIKGTELELSNLPGGPSVSAFI 391
R +V+V+GA IG +S+ LK N KVS+L L+D G ++ ++ +V +
Sbjct: 27 RAFKVAVLGAGGGIGQPLSMLLKLNDKVSELALFDIRGA-PGVAADIGHINTTSNVVGYA 85
Query: 392 -GDTNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAIS 568
D LE+A++ +++V++ + +PRKPG TR+ + NA +++ L A EA +
Sbjct: 86 PDDKGLEKALNGADVVIIPAGVPRKPGMTRDDLFATNASIVRDLAFAAGETCPEAKYLVV 145
Query: 569 TNPINYLIPFASTVMYKYGCYNPSKMFGITHIDTSRSRSFVAKALKINAQ 718
TNP+N +P + + G + P +FG+T +D+ R+ F ++ A+
Sbjct: 146 TNPVNSTVPIFKKALERVGVHQPKHLFGVTTLDSVRASRFTSQVTNGKAE 195
>UniRef50_Q6FL22 Cluster: Malate dehydrogenase; n=1; Candida
glabrata|Rep: Malate dehydrogenase - Candida glabrata
(Yeast) (Torulopsis glabrata)
Length = 373
Score = 93.5 bits (222), Expect = 5e-18
Identities = 51/162 (31%), Positives = 93/162 (57%)
Frame = +2
Query: 218 VQVSVIGAASDIGSYVSLFLKRNSKVSKLHLYDDDDRIKGTELELSNLPGGPSVSAFIGD 397
V+V+V+GA+ +G +SL LK N+ +S+L LYD +G +LS++ + D
Sbjct: 2 VKVAVLGASGGVGQPLSLLLKLNTMISELALYDIK-LAEGVATDLSHINTNADCVGYSTD 60
Query: 398 TNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAISTNP 577
++ QA+ + +VV+ + +PR+PG TR+ + NA +++ L +A A + I +NP
Sbjct: 61 -DIGQALKGAAVVVIPAGVPRRPGITRDDLFKLNAGIVKNLVSNVAKHCPNARLLIISNP 119
Query: 578 INYLIPFASTVMYKYGCYNPSKMFGITHIDTSRSRSFVAKAL 703
+N LIP A + + G + + G+T +D R+ +F+A+ L
Sbjct: 120 VNSLIPVAVETLKRCGVFQAGNVMGVTTLDLVRAETFLAEYL 161
>UniRef50_P32419 Cluster: Malate dehydrogenase, peroxisomal; n=24;
Eukaryota|Rep: Malate dehydrogenase, peroxisomal -
Saccharomyces cerevisiae (Baker's yeast)
Length = 343
Score = 93.5 bits (222), Expect = 5e-18
Identities = 49/164 (29%), Positives = 94/164 (57%)
Frame = +2
Query: 218 VQVSVIGAASDIGSYVSLFLKRNSKVSKLHLYDDDDRIKGTELELSNLPGGPSVSAFIGD 397
V+V+++GA+ +G +SL LK + VS+L LYD +G +LS++ S + D
Sbjct: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELALYDIR-AAEGIGKDLSHINTNSSCVGYDKD 60
Query: 398 TNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAISTNP 577
+ +E + ++ +V++ + +PRKPG TR+ + NA +++ L A+ A + + +NP
Sbjct: 61 S-IENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNP 119
Query: 578 INYLIPFASTVMYKYGCYNPSKMFGITHIDTSRSRSFVAKALKI 709
+N L+P A + K G + P + G+T++D R+ +F+ L +
Sbjct: 120 VNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLML 163
>UniRef50_A7SQS1 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 254
Score = 89.8 bits (213), Expect = 6e-17
Identities = 41/122 (33%), Positives = 74/122 (60%)
Frame = +2
Query: 335 GTELELSNLPGGPSVSAFIGDTNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQ 514
G +LS++ V++ G +L+ A+ ++V + + +PRKPG TR+ + NA +++
Sbjct: 7 GVAADLSHISTRAKVTSHQGPDDLKAALEGCSVVAIPAGVPRKPGMTRDDLFNTNASIVK 66
Query: 515 RLCKAIAAQNQEAFVAISTNPINYLIPFASTVMYKYGCYNPSKMFGITHIDTSRSRSFVA 694
L +A A +A + I +NP+N +P AS V K G Y+P+++ G+T +D R+ +FVA
Sbjct: 67 NLSEACAKHCPKAIICIISNPVNSTVPIASEVYKKAGVYDPARILGVTTLDIVRAHTFVA 126
Query: 695 KA 700
+A
Sbjct: 127 EA 128
>UniRef50_Q6CP51 Cluster: Similar to sp|P22133 Saccharomyces
cerevisiae YOL126c MDH2 malate dehydrogenase; n=1;
Kluyveromyces lactis|Rep: Similar to sp|P22133
Saccharomyces cerevisiae YOL126c MDH2 malate
dehydrogenase - Kluyveromyces lactis (Yeast) (Candida
sphaerica)
Length = 404
Score = 84.2 bits (199), Expect = 3e-15
Identities = 60/181 (33%), Positives = 104/181 (57%), Gaps = 19/181 (10%)
Frame = +2
Query: 206 QKRNVQVSVIGAASDIGSYVSLFLKRN---------SKVSKLHLYD-DDDRIKGTELELS 355
+K +++SV+GAA IG +SL LK N S +L LYD + D I GT +LS
Sbjct: 43 EKEILKISVLGAAGGIGQSLSLLLKSNAGFLLPHETSTHIRLSLYDVNKDAIVGTAADLS 102
Query: 356 NLPGGPSVSA-FIGDTN--LEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCK 526
++ + +A + D+N + Q + ++++V++ + +PRKPG +R+ ++G NA +I+ L +
Sbjct: 103 HIDTPITTTAHYPDDSNGGIGQCLSNASVVIIPAGVPRKPGMSRDDLIGVNAKIIKSLGE 162
Query: 527 AIA--AQNQEAFVAISTNPINYLIPFASTVMYK---YGCYN-PSKMFGITHIDTSRSRSF 688
IA + V + +NPIN L+P + + + G N S+++GIT +D RS +F
Sbjct: 163 DIAKYCDLNKVHVLVISNPINSLVPLLTNTLIRSDANGNSNIESRVYGITQLDLVRSSTF 222
Query: 689 V 691
V
Sbjct: 223 V 223
>UniRef50_A7TSF5 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 387
Score = 82.6 bits (195), Expect = 9e-15
Identities = 53/168 (31%), Positives = 92/168 (54%), Gaps = 6/168 (3%)
Frame = +2
Query: 206 QKRNVQVSVIGAASDIGSYVSLFLK---RNSKVSKLHLYDDDDRIK---GTELELSNLPG 367
+ V+++VIGAA IG +SL L+ +N+ ++LHL D +K G +LS++
Sbjct: 37 KSNQVKITVIGAAGGIGQSLSLLLRTSLQNNNDNQLHLALFDVNMKVLNGVHADLSHVNT 96
Query: 368 GPSVSAFIGDTNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQ 547
+S NL ++ SNLV++ + +PRKPG TR+ + NA +I+ + + + +
Sbjct: 97 NMKLSLH---DNLRDSLVDSNLVIIPAGVPRKPGMTRDDLFNINAGIIKGIAQELNTIDS 153
Query: 548 EAFVAISTNPINYLIPFASTVMYKYGCYNPSKMFGITHIDTSRSRSFV 691
FV + +NP+N L+P +V+ + FGIT +D R+ +FV
Sbjct: 154 TPFVLLISNPVNSLLPVLQSVLNDVYL---GRCFGITELDLVRASTFV 198
>UniRef50_P22133 Cluster: Malate dehydrogenase, cytoplasmic; n=3;
Saccharomycetaceae|Rep: Malate dehydrogenase,
cytoplasmic - Saccharomyces cerevisiae (Baker's yeast)
Length = 377
Score = 81.4 bits (192), Expect = 2e-14
Identities = 53/182 (29%), Positives = 101/182 (55%), Gaps = 19/182 (10%)
Frame = +2
Query: 203 LQKRNVQVSVIGAASDIGSYVSLFLKR---------NSKVSKLHL--YD-DDDRIKGTEL 346
+++ +++++++GAA IG +SL LK N V+ +HL YD + + I G
Sbjct: 9 IEQDSLKIAILGAAGGIGQSLSLLLKAQLQYQLKESNRSVTHIHLALYDVNQEAINGVTA 68
Query: 347 ELSNLPGGPSVSAFIGDTNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCK 526
+LS++ SVS+ +E +H++++VV+ + +PRKPG TR+ + NA +I +L
Sbjct: 69 DLSHIDTPISVSSHSPAGGIENCLHNASIVVIPAGVPRKPGMTRDDLFNVNAGIISQLGD 128
Query: 527 AIA--AQNQEAFVAISTNPINYLIP-FASTVMYKYGCYNPS----KMFGITHIDTSRSRS 685
+IA + FV + +NP+N L+P S ++ + S ++ G+T +D R+ +
Sbjct: 129 SIAECCDLSKVFVLVISNPVNSLVPVMVSNILKNHPQSRNSGIERRIMGVTKLDIVRAST 188
Query: 686 FV 691
F+
Sbjct: 189 FL 190
>UniRef50_UPI0000DB76D8 Cluster: PREDICTED: similar to CG7998-PA;
n=2; Apis mellifera|Rep: PREDICTED: similar to CG7998-PA
- Apis mellifera
Length = 333
Score = 79.0 bits (186), Expect = 1e-13
Identities = 46/168 (27%), Positives = 91/168 (54%), Gaps = 1/168 (0%)
Frame = +2
Query: 218 VQVSVIGAASDIGSYVSLFLKRNSKVSKLHLYDDDDRIKGTELELSNLPGGPSVSAFIGD 397
++V+++GA S G+ +SLFLK++ + +L ++D++ G L+L+ + VS
Sbjct: 1 MKVAILGARSKTGNCLSLFLKQSPLIDELAIFDNNSSTYGLALDLNYIDTKCKVSTCNHP 60
Query: 398 TN-LEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAISTN 574
LE+ + + +V++V+ + N ++L +NA ++ L I + +A +AI N
Sbjct: 61 EKCLEETLQGAKIVMIVTD---RTSNESNEVLKSNAIILSDLLPNIIKFSPQAMLAIVMN 117
Query: 575 PINYLIPFASTVMYKYGCYNPSKMFGITHIDTSRSRSFVAKALKINAQ 718
PIN LIP + K G Y +++FG+ + + ++ SF A + I +
Sbjct: 118 PINSLIPLTMEMYKKAGIYEYNRIFGVMNFECLKANSFTADLINIEPE 165
>UniRef50_Q5ENS5 Cluster: Malate dehydrogenase; n=1; Heterocapsa
triquetra|Rep: Malate dehydrogenase - Heterocapsa
triquetra (Dinoflagellate)
Length = 402
Score = 78.6 bits (185), Expect = 1e-13
Identities = 48/168 (28%), Positives = 88/168 (52%), Gaps = 9/168 (5%)
Frame = +2
Query: 221 QVSVIGAASDIGSYVSLFLKRNSKVSKLHLYDDDDRI---KGTELELSNLPGGPSVSAFI 391
+V V G A IG + L + + V +L ++D + + +G +L +L +V ++
Sbjct: 82 KVCVCGGAGGIGQPLCLLMAMDPNVKELCVFDLNVAMVPAQGVATDLGHLEKKAAVKGYV 141
Query: 392 GDT------NLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEA 553
+ NLE+ + +LV++ + MPRKPG TR+ + NA + + + +A A +A
Sbjct: 142 MEVGQKPVDNLEECLTGCHLVLIPAGMPRKPGQTRDDLFKINADIAKGIVEACAKYCPDA 201
Query: 554 FVAISTNPINYLIPFASTVMYKYGCYNPSKMFGITHIDTSRSRSFVAK 697
+ + NP+N ++P A +YK +P K+ GIT +D R+ FV +
Sbjct: 202 MLGMIVNPVNSVVP-AMAELYKKKGLDPMKIVGITTLDVVRANKFVVR 248
>UniRef50_A3BMG8 Cluster: Putative uncharacterized protein; n=3;
Oryza sativa|Rep: Putative uncharacterized protein -
Oryza sativa subsp. japonica (Rice)
Length = 405
Score = 74.9 bits (176), Expect = 2e-12
Identities = 39/115 (33%), Positives = 66/115 (57%)
Frame = +2
Query: 191 NTLILQKRNVQVSVIGAASDIGSYVSLFLKRNSKVSKLHLYDDDDRIKGTELELSNLPGG 370
N ++ Q +V+++GAA IG +SL +K + VS LHLYD + + G +L +
Sbjct: 69 NRVVAQAGGYKVAILGAAGGIGQPLSLLVKMSPLVSALHLYDIAN-VDGVTADLGHCNTP 127
Query: 371 PSVSAFIGDTNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIA 535
V+ F G L + ++VV+ + +PRKPG TR+ + G NA +++ L +A+A
Sbjct: 128 AKVAGFTGKEELAGCLAGVDVVVIPAGVPRKPGMTRDDLFGINAGIVRELVEAVA 182
>UniRef50_Q4QDF0 Cluster: Glycosomal malate dehydrogenase; n=9;
Trypanosomatidae|Rep: Glycosomal malate dehydrogenase -
Leishmania major
Length = 322
Score = 74.9 bits (176), Expect = 2e-12
Identities = 54/171 (31%), Positives = 85/171 (49%), Gaps = 8/171 (4%)
Frame = +2
Query: 218 VQVSVIGAASDIGSYVSLFLKRNSKV-SKLHLYDDDDRIKGTELELSNLPGGPSVSAF-- 388
V V V+GAA IG +SL L R S L L+D G +LS++ F
Sbjct: 2 VNVCVVGAAGGIGQSLSLLLVRQLPYGSTLSLFDVVGAA-GVAADLSHVDNAGVQVKFAE 60
Query: 389 --IG---DTNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEA 553
IG D L + ++ VMV+ +PRKPG TR+ + NA +I L A+ + +A
Sbjct: 61 GKIGHKRDPALAELAKGVDVFVMVAGVPRKPGMTRDDLFKINAGIILDLVLTCASSSPKA 120
Query: 554 FVAISTNPINYLIPFASTVMYKYGCYNPSKMFGITHIDTSRSRSFVAKALK 706
I TNP+N + A+ + G Y+ +++ G++ +D R+ F+ +A K
Sbjct: 121 VFCIVTNPVNSTVAIAAEALKSLGVYDRNRLLGVSLLDGLRATCFINEARK 171
>UniRef50_UPI0000D55CD8 Cluster: PREDICTED: similar to Malate
DeHydrogenase family member (mdh-1); n=1; Tribolium
castaneum|Rep: PREDICTED: similar to Malate
DeHydrogenase family member (mdh-1) - Tribolium
castaneum
Length = 374
Score = 74.5 bits (175), Expect = 2e-12
Identities = 37/158 (23%), Positives = 82/158 (51%)
Frame = +2
Query: 224 VSVIGAASDIGSYVSLFLKRNSKVSKLHLYDDDDRIKGTELELSNLPGGPSVSAFIGDTN 403
V+++ S +GS ++L LK+N + +L L+D+++ +L+ + + +F +
Sbjct: 31 VTLLDTLSSVGSNLALLLKQNLDIYELRLFDEENNTNAFACDLNEIDTRTKLKSF-SCKS 89
Query: 404 LEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAISTNPIN 583
L+ AI +++V+ KPG+++ ++ N ++ + +A N EA I+ P+
Sbjct: 90 LKNAIVGAHVVISTGGCQEKPGSSQRELFDKNLDNVRNVAMFLAEFNPEAIYCIAKPPVE 149
Query: 584 YLIPFASTVMYKYGCYNPSKMFGITHIDTSRSRSFVAK 697
L+P S K Y+P K+ G+ + + + +F+A+
Sbjct: 150 ALVPMVSEEYKKAETYDPRKIIGVATVASMIANTFIAE 187
>UniRef50_Q75AT4 Cluster: ADL164Cp; n=2; Saccharomycetales|Rep:
ADL164Cp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 381
Score = 73.3 bits (172), Expect = 5e-12
Identities = 55/183 (30%), Positives = 98/183 (53%), Gaps = 23/183 (12%)
Frame = +2
Query: 212 RNVQVSVIGAASDIGSYVSLFLKR-------NSKVS-KLHLYD-DDDRIKGTELELSNLP 364
+ V+V+V+GAA IG +SL LK ++ S +L LYD D + G +LS++
Sbjct: 22 QRVRVAVLGAAGGIGQPLSLLLKTQLAQVLGDANASLELALYDVAADALAGVAADLSHVN 81
Query: 365 GGPSVSAFIGDTN-----LEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKA 529
VS + + L +A+ +++VV+ + +PRKPG TR+ ++ NA +I+ L K
Sbjct: 82 TPVEVSHHVPSSREDEEALREALTGASVVVIPAGVPRKPGMTRDDLININAGIIKTLAKG 141
Query: 530 I--AAQNQEAFVAISTNPINYLIPFASTVMYKYGCYNPS-------KMFGITHIDTSRSR 682
I A ++ FV + +NP+N L+P + ++ + ++FG+T +D R+
Sbjct: 142 IAGACDLEKVFVLVISNPVNSLVPVMVRQLIRHAEAKQAPHAGVERRVFGVTQLDMVRAS 201
Query: 683 SFV 691
+FV
Sbjct: 202 AFV 204
>UniRef50_UPI00005A0834 Cluster: PREDICTED: similar to Malate
dehydrogenase, mitochondrial precursor; n=1; Canis lupus
familiaris|Rep: PREDICTED: similar to Malate
dehydrogenase, mitochondrial precursor - Canis
familiaris
Length = 245
Score = 72.9 bits (171), Expect = 7e-12
Identities = 31/81 (38%), Positives = 50/81 (61%)
Frame = +2
Query: 455 PRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAISTNPINYLIPFASTVMYKYGCYN 634
PRKPG TR+ + NA ++ A A EA + + +NP+N IP A+ V K+G Y+
Sbjct: 61 PRKPGMTRDDLFNTNASVVATPTAACAQHCPEAMICVISNPVNSTIPIATEVFKKHGAYD 120
Query: 635 PSKMFGITHIDTSRSRSFVAK 697
P+K+F +T +D R+ +F+A+
Sbjct: 121 PNKIFRVTTLDIVRANTFIAE 141
>UniRef50_Q4Q3J5 Cluster: Malate dehydrogenase, putative; n=5;
Trypanosomatidae|Rep: Malate dehydrogenase, putative -
Leishmania major
Length = 342
Score = 71.3 bits (167), Expect = 2e-11
Identities = 48/169 (28%), Positives = 83/169 (49%), Gaps = 5/169 (2%)
Frame = +2
Query: 221 QVSVIGAASDIGSYVSLFLKRNSKVSKL----HLYDDDDRIKGTELELSNLPGGPSVSAF 388
+V + G ++ +G +SL LK N V +L DDD G +LS++ P V
Sbjct: 16 KVVLFGCSNAVGQPLSLLLKMNPHVEELVCCNTAADDDVPGSGIAADLSHIDTLPKVHYA 75
Query: 389 IGDTNLEQAIHSSNLV-VMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAI 565
+ + + L+ V R+ L A AP ++R+ A+A+ + VA+
Sbjct: 76 TDEGQWPALLRDAQLILVCFGSSFDLLREDRDIALKAAAPTMRRVMAAVASSDTTGNVAV 135
Query: 566 STNPINYLIPFASTVMYKYGCYNPSKMFGITHIDTSRSRSFVAKALKIN 712
++P+N L PF + ++ G ++P K+FG+T +D R+R VA L +N
Sbjct: 136 VSSPVNALTPFCAELLKASGKFDPRKLFGVTTLDVIRTRKLVAGTLHMN 184
>UniRef50_O26290 Cluster: Malate dehydrogenase; n=2;
Methanobacteriaceae|Rep: Malate dehydrogenase -
Methanobacterium thermoautotrophicum
Length = 325
Score = 66.9 bits (156), Expect = 5e-10
Identities = 38/169 (22%), Positives = 88/169 (52%), Gaps = 4/169 (2%)
Frame = +2
Query: 218 VQVSVIGAASDIGSYVSLFLKRNSKVSKLHLYDDDDRIK---GTELELSNLPGGPSVSAF 388
++VS+IG+ +G +L L V LHL + ++ G L++S+ VS
Sbjct: 1 MKVSIIGSTGRVGRATALCLAEEEAVKTLHLISRKESLEQNLGEVLDMSDALAAKGVSVK 60
Query: 389 IGDTNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAIS 568
+ ++ + ++ S +VV+ + +PR R+ + N ++ + IA ++ + +
Sbjct: 61 LENSADIENVYGSRIVVITAGVPRTADMDRDDLAFKNGRIVADYARQIARFAPDSIILVV 120
Query: 569 TNPINYLIPFASTVMYKYGCYNPSKMFGI-THIDTSRSRSFVAKALKIN 712
TNP++ + + V +Y ++PS++FG+ H+D+ R ++++A+ ++
Sbjct: 121 TNPVDVM----TYVALRYSGFHPSRVFGLGNHLDSLRLKNYMARHFNVH 165
>UniRef50_A7I5J9 Cluster: L-lactate dehydrogenase precursor; n=1;
Candidatus Methanoregula boonei 6A8|Rep: L-lactate
dehydrogenase precursor - Methanoregula boonei (strain
6A8)
Length = 332
Score = 66.5 bits (155), Expect = 6e-10
Identities = 40/168 (23%), Positives = 86/168 (51%), Gaps = 4/168 (2%)
Frame = +2
Query: 221 QVSVIGAASDIGSYVSLFLKRNSKVSKLHLYDDDDR---IKGTELELSNLPGGPSVSAFI 391
+V++IGA ++G++ + + + V ++ LY + R +KG + ++ + +
Sbjct: 3 KVTIIGATGNVGTFAAYAVSVDPHVHEILLYGREGREAFLKGLAQDFADSFAARGTNIRV 62
Query: 392 GDTNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAIST 571
T + + S++VV+ + PR PG R + NA +I + + I + + + T
Sbjct: 63 TWTTSLKDVAGSDIVVITAGTPRGPGQNRLDLALGNARIIAPMARTIGTIAPDTKIIMVT 122
Query: 572 NPINYLIPFASTVMYKYGCYNPSKMFGI-THIDTSRSRSFVAKALKIN 712
NP++ + + V KY P+++FG+ TH+D+ R +S +A K++
Sbjct: 123 NPVDVM----TCVALKYSGLKPNQVFGLGTHLDSMRLKSLIASYFKVH 166
>UniRef50_A2SSY4 Cluster: L-lactate dehydrogenase; n=3;
Methanomicrobiales|Rep: L-lactate dehydrogenase -
Methanocorpusculum labreanum (strain ATCC 43576 / DSM
4855 / Z)
Length = 319
Score = 66.1 bits (154), Expect = 8e-10
Identities = 44/170 (25%), Positives = 88/170 (51%), Gaps = 6/170 (3%)
Frame = +2
Query: 221 QVSVIGAASDIGSYVSLFLKRNSKVSKLHLYD---DDDRIKGTELEL--SNLPGGPSVSA 385
+V++IGA +GSYV+ + + V ++ LY ++ + G ++ S G +
Sbjct: 3 KVTIIGATGQVGSYVAHAVSQFPHVQEMCLYGRPGNEQYLDGLAHDMMDSFAARGTNTRV 62
Query: 386 FIGDTNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAI 565
G T E + S+++V+ S +PRK TR + NA +++ + + EA + +
Sbjct: 63 TFGTTPKE--LRGSDIIVLTSGVPRKATQTRLDLALENARIVKVFAEQVGRMAPEAILLV 120
Query: 566 STNPINYLIPFASTVMYKYGCYNPSKMFGI-THIDTSRSRSFVAKALKIN 712
TNP++ + +TV KY P ++FG+ TH+D+ R ++ +A+ ++
Sbjct: 121 VTNPVDIM----TTVALKYSGMMPHRVFGLGTHLDSMRLKACLAEFFNVH 166
>UniRef50_P16115 Cluster: L-lactate dehydrogenase; n=4;
Thermotogaceae|Rep: L-lactate dehydrogenase - Thermotoga
maritima
Length = 319
Score = 63.7 bits (148), Expect = 4e-09
Identities = 44/163 (26%), Positives = 86/163 (52%), Gaps = 3/163 (1%)
Frame = +2
Query: 218 VQVSVIGAASDIGSYVSLFLKRNSKVSKLHLYD-DDDRIKGTELELSN-LPGGPSVSAFI 391
+++ ++G +GS + L ++ L D D R +G L+L + P + +
Sbjct: 1 MKIGIVGLGR-VGSSTAFALLMKGFAREMVLIDVDKKRAEGDALDLIHGTPFTRRANIYA 59
Query: 392 GDTNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAIST 571
GD + S++V++ + +P+KPG TR Q+LG NA +++ + + ++ ++ V + T
Sbjct: 60 GDY---ADLKGSDVVIVAAGVPQKPGETRLQLLGRNARVMKEIARNVSKYAPDSIVIVVT 116
Query: 572 NPINYLIPFASTVMYKYGCYNPSKMFGI-THIDTSRSRSFVAK 697
NP++ L F K +P K+FG T +DT+R R+ +A+
Sbjct: 117 NPVDVLTYF----FLKESGMDPRKVFGSGTVLDTARLRTLIAQ 155
>UniRef50_Q6VVP7 Cluster: Malate dehydrogenase; n=6; Plasmodium|Rep:
Malate dehydrogenase - Plasmodium falciparum
Length = 313
Score = 63.3 bits (147), Expect = 6e-09
Identities = 49/169 (28%), Positives = 91/169 (53%), Gaps = 3/169 (1%)
Frame = +2
Query: 221 QVSVIGAASDIGSYVS-LFLKRNSKVSKLHLYDDDDRI-KGTELELSNLPGGPSVSAFIG 394
++++IG+ IG+ V L L N + L LYD I +G L+L + V+ I
Sbjct: 3 KIALIGSGQ-IGAIVGELCLLEN--LGDLILYDVVPGIPQGKALDLKHFSTILGVNRNIL 59
Query: 395 DTNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAISTN 574
TN + I ++++V+ + + RK G TRE ++G N +++ + +++ +AFV +N
Sbjct: 60 GTNQIEDIKDADIIVITAGVQRKEGMTREDLIGVNGKIMKSVAESVKLHCSKAFVICVSN 119
Query: 575 PINYLIPFASTVMYKYGCYNPSKMFGITHI-DTSRSRSFVAKALKINAQ 718
P++ ++ V +K+ K+ G+ I DTSR S +A LK++A+
Sbjct: 120 PLDIMV----NVFHKFSNLPHEKICGMAGILDTSRYCSLIADKLKVSAE 164
>UniRef50_Q8TWG5 Cluster: Malate dehydrogenase; n=2;
Euryarchaeota|Rep: Malate dehydrogenase - Methanopyrus
kandleri
Length = 317
Score = 63.3 bits (147), Expect = 6e-09
Identities = 44/168 (26%), Positives = 84/168 (50%), Gaps = 4/168 (2%)
Frame = +2
Query: 221 QVSVIGAASDIGSYVSLFLKRNSKVSKLHLY---DDDDRIKGTELELSNLPGGPSVSAFI 391
+V+VIGA +GS + L V+++ L D+++G ++ + A I
Sbjct: 3 KVAVIGATGRVGSTAAARLALLDCVNEVTLIARPKSVDKLRGLRRDILDSLAAAQKDAEI 62
Query: 392 GDTNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAIST 571
++++VM + +PRKPG TR + NA +I++ + +A +N EA V + T
Sbjct: 63 TIGCERDDYVDADVIVMTAGIPRKPGQTRLDLTKDNAAIIKKYLEGVAEENPEAIVLVVT 122
Query: 572 NPINYLIPFASTVMYKYGCYNPSKMFGI-THIDTSRSRSFVAKALKIN 712
NP++ L + V K +++ G+ TH+D+ R + +AK ++
Sbjct: 123 NPVDVL----TYVALKVSGLPKNRVIGLGTHLDSMRFKVLIAKHFNVH 166
>UniRef50_Q86S07 Cluster: NAD-specific malate dehydrogenase 2; n=1;
Entamoeba histolytica|Rep: NAD-specific malate
dehydrogenase 2 - Entamoeba histolytica
Length = 329
Score = 62.5 bits (145), Expect = 1e-08
Identities = 45/164 (27%), Positives = 80/164 (48%), Gaps = 5/164 (3%)
Frame = +2
Query: 218 VQVSVIGAASDIGSYVSLFLKRNSKVSK---LHLYD-DDDRIKGTELELSNLPGGPSVSA 385
+ V + GAA IG + + R LHLYD +D +KG +EL++ P +
Sbjct: 16 LHVLITGAAGQIGYNLCFLIGRGFLFDCDVILHLYDLNDMALKGLSMELTDCCL-PKLKG 74
Query: 386 FIGDTNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAA-QNQEAFVA 562
I T + A + ++ ++V+ +PRKPG R ++ N +++ KA+ N++ V
Sbjct: 75 IISTTEIALAFSNVDVAIIVAGVPRKPGMQRSDLINVNKKVMEMNGKALGTYSNKDVRVV 134
Query: 563 ISTNPINYLIPFASTVMYKYGCYNPSKMFGITHIDTSRSRSFVA 694
+ NP N + V+ K P + +T +D +R+ +FVA
Sbjct: 135 VVANPAN----TNAYVICKTSGIPPEHITALTRLDQNRATAFVA 174
>UniRef50_Q86DP2 Cluster: Malate dehydrogenase; n=11; Fungi/Metazoa
group|Rep: Malate dehydrogenase - Plicopurpura patula
Length = 229
Score = 62.5 bits (145), Expect = 1e-08
Identities = 28/72 (38%), Positives = 44/72 (61%)
Frame = +2
Query: 485 MLGANAPLIQRLCKAIAAQNQEAFVAISTNPINYLIPFASTVMYKYGCYNPSKMFGITHI 664
+ NA +++ L IA A + I TNP+N +P AS V+ K G Y+P ++FG+T +
Sbjct: 2 LFNTNAGIVRDLTDRIAKVCPTAMLGIITNPVNSTVPIASEVLKKRGVYDPKRVFGVTTL 61
Query: 665 DTSRSRSFVAKA 700
D RS +F+A+A
Sbjct: 62 DVVRSNTFIAEA 73
>UniRef50_Q3J7E7 Cluster: Malate dehydrogenase; n=5;
Gammaproteobacteria|Rep: Malate dehydrogenase -
Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848)
Length = 311
Score = 62.5 bits (145), Expect = 1e-08
Identities = 45/161 (27%), Positives = 86/161 (53%), Gaps = 3/161 (1%)
Frame = +2
Query: 221 QVSVIGAASDIGSYVSLFLKRNSKVSKLHLYDDDDRI-KGTELELS-NLPGGPSVSAFIG 394
+++++GA +G + FL +N +L L D + + +G L++ + P + G
Sbjct: 5 KITIVGAGR-VGEATAQFLVKNELCRELVLLDAQEGVAQGAALDIQQSAPLFDFDARVTG 63
Query: 395 DTNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAISTN 574
TN E I S+LVV+ + PRKPG +R +L +N P+I + + ++ V I TN
Sbjct: 64 STNYE-LIADSDLVVITAGKPRKPGMSRSDVLDSNLPIITDIMNNVMRFAPQSLVMIVTN 122
Query: 575 PINYLIPFASTVMYKYGCYNPSKMFGITHI-DTSRSRSFVA 694
P++ L A +++ ++ +++FG + D++R SF+A
Sbjct: 123 PVDVLTYHA----WRHCGWDRARVFGQAGVLDSARMASFIA 159
>UniRef50_Q979N9 Cluster: Malate dehydrogenase; n=4;
Thermoplasmatales|Rep: Malate dehydrogenase -
Thermoplasma volcanium
Length = 325
Score = 60.9 bits (141), Expect = 3e-08
Identities = 45/175 (25%), Positives = 93/175 (53%), Gaps = 9/175 (5%)
Frame = +2
Query: 221 QVSVIGAASDIGSYVSLFLKRNSKVSKLHLYDDDDRI-KGTELELSNLPGGPS------- 376
++SVIGA + +G+ V+ FL ++ ++L+D D I +G L++ G P
Sbjct: 5 KISVIGAGN-VGATVAQFLA-TKELGDVYLFDVVDGIPEGKALDIQE--GAPHWGYDLDV 60
Query: 377 VSAFIGDTNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAF 556
V D++ + + S+++V+ + M RKPG +RE + N +I + K I + ++
Sbjct: 61 VGFSTSDSSNYKNMEGSDVIVVTAGMARKPGMSREDLFDKNVEIIADVSKNIKKYSPDSI 120
Query: 557 VAISTNPINYLIPFASTVMYKYGCYNPSKMFGI-THIDTSRSRSFVAKALKINAQ 718
+ + +NP + + + + K +P ++ G+ +D+SR R+F+AK L ++ +
Sbjct: 121 IVVVSNPADIM----AYALQKISGVDPQRIMGLGGSLDSSRFRTFLAKELDVSVE 171
>UniRef50_P22988 Cluster: L-lactate dehydrogenase A; n=19;
Magnoliophyta|Rep: L-lactate dehydrogenase A - Hordeum
vulgare (Barley)
Length = 356
Score = 60.9 bits (141), Expect = 3e-08
Identities = 45/179 (25%), Positives = 95/179 (53%), Gaps = 3/179 (1%)
Frame = +2
Query: 191 NTLILQKRNVQVSVIGAASDIGSYVSLFLKRNSKVSKLHLYDD-DDRIKGTELELSNLPG 367
++ + +R ++SVIGA + +G ++ + + ++ L D D+++G L+L +
Sbjct: 35 SSAVPHRRLTKISVIGAGN-VGMAIAQTILTQNLADEIALVDALPDKLRGEALDLQHAAA 93
Query: 368 G-PSVSAFIGDTNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQN 544
P V D + + +S+LV++ + + PG TR +L N L +++ +A +
Sbjct: 94 FLPRVRISGTDAAVTK---NSDLVIVTAGARQIPGETRLNLLQRNVALYRKIVPPVAEHS 150
Query: 545 QEAFVAISTNPINYLIPFASTVMYKYGCYNPSKMFGI-THIDTSRSRSFVAKALKINAQ 718
+A + + +NP++ L + V +K + S++ G T++D+SR R +A+ L +NAQ
Sbjct: 151 PDALLLVVSNPVDVL----TYVAWKLSGFPASRVIGSGTNLDSSRFRFLIAEHLDVNAQ 205
>UniRef50_Q017A6 Cluster: Malate dehydrogenase; n=2; cellular
organisms|Rep: Malate dehydrogenase - Ostreococcus tauri
Length = 477
Score = 59.7 bits (138), Expect = 7e-08
Identities = 25/75 (33%), Positives = 46/75 (61%)
Frame = +2
Query: 473 TREQMLGANAPLIQRLCKAIAAQNQEAFVAISTNPINYLIPFASTVMYKYGCYNPSKMFG 652
TR+ + N +++ L +AIA A + + +NP+N +P A+ V+ G Y+P K+FG
Sbjct: 2 TRDDLFAINGGIVKGLVEAIADNCPNAMINMISNPVNSTVPIAAEVLKAKGKYDPKKLFG 61
Query: 653 ITHIDTSRSRSFVAK 697
+T +D R+++F A+
Sbjct: 62 VTTLDVVRAKTFYAE 76
>UniRef50_Q8ZVB2 Cluster: Malate dehydrogenase; n=14;
Thermoprotei|Rep: Malate dehydrogenase - Pyrobaculum
aerophilum
Length = 309
Score = 59.7 bits (138), Expect = 7e-08
Identities = 40/165 (24%), Positives = 88/165 (53%), Gaps = 2/165 (1%)
Frame = +2
Query: 224 VSVIGAASDIGSYVSLFLKRNSKVSKLHLYDDDDRI-KGTELELSNLPGGPSVSAFIGDT 400
+++IG+ +G+ ++ + +K+ L D + +G L+++++ + +
Sbjct: 2 ITIIGSGR-VGTAAAVIMGLMKLDNKILLIDIVKGLPQGEALDMNHMSSILGLDVEYVGS 60
Query: 401 NLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAISTNPI 580
N + I S+L+++ + +PRKPG TREQ+L ANA ++ + + I ++ V ++TNP+
Sbjct: 61 NEYKDIEGSDLIIVTAGLPRKPGMTREQLLEANAKIVAEIGREIKKYAPDSIVILTTNPL 120
Query: 581 NYLIPFASTVMYKYGCYNPSKMFGITHI-DTSRSRSFVAKALKIN 712
+ + + VM+K + ++ G + + D R + AK L I+
Sbjct: 121 DAM----TYVMWKATGFPRERVIGFSGVLDAGRLAFYAAKKLGIS 161
>UniRef50_A7GYI6 Cluster: Lactate/malate dehydrogenase, NAD binding
domain protein; n=2; Campylobacter|Rep: Lactate/malate
dehydrogenase, NAD binding domain protein -
Campylobacter curvus 525.92
Length = 297
Score = 58.8 bits (136), Expect = 1e-07
Identities = 48/171 (28%), Positives = 90/171 (52%), Gaps = 4/171 (2%)
Frame = +2
Query: 218 VQVSVIGAASDIGSYVSLFLKRNSKVSKLHLYD---DDDRIKGTELELSNLPGGPSVSAF 388
+++SVIGA + +G+ ++ L ++ L D D R K ++ + +S
Sbjct: 1 MKISVIGAGN-VGASIAYALAMRGVCDEIALVDIFGDVARAKAIDIAQAGCVFCGCLSTA 59
Query: 389 IGDTNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAIS 568
GD I +S++VV+ + PRK G TRE +L NA ++++ + IA A V I
Sbjct: 60 GGDDFA--LIEASDIVVVTAGSPRKEGQTREDLLLKNAQVVKQTAQNIAKFAPNAIVIIV 117
Query: 569 TNPINYLIPFASTVMYKYGCYNPSKMFGIT-HIDTSRSRSFVAKALKINAQ 718
TNP++ ++ TV+ +Y ++ S++ G+ +D++R R +A I+A+
Sbjct: 118 TNPLDVMV---WTVL-RYSGFDRSRVIGMAGELDSARCRYEIASLKDISAK 164
>UniRef50_A7DRG3 Cluster: Lactate/malate dehydrogenase; n=1;
Candidatus Nitrosopumilus maritimus SCM1|Rep:
Lactate/malate dehydrogenase - Candidatus Nitrosopumilus
maritimus SCM1
Length = 304
Score = 58.0 bits (134), Expect = 2e-07
Identities = 39/161 (24%), Positives = 85/161 (52%), Gaps = 2/161 (1%)
Frame = +2
Query: 224 VSVIGAASDIGSYVSLFLKRNSKVSKLHLYDDDDRI-KGTELELSNLPGGPSVSAFIGDT 400
+++IG+ +G +LF ++ L D + + +G ++++++ + + +
Sbjct: 2 ITIIGSGK-VGGDAALFSALKRLDDQILLLDVAEGLPQGEAMDINHMLSEQGIDVEVKGS 60
Query: 401 NLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAISTNPI 580
N + + SN+VV+V+ RKPG TR +L NA +++ + + + ++ + TNP+
Sbjct: 61 NNFEDMKGSNIVVVVAGSGRKPGMTRMDLLKINASIVKSVVENVKKYADDSMIIPVTNPL 120
Query: 581 NYLIPFASTVMYKYGCYNPSKMFGI-THIDTSRSRSFVAKA 700
+ P A + YK ++ S++FG+ +D SR R F+ +A
Sbjct: 121 D---PMA-YITYKVSGFDRSRVFGMGGMLDLSRFRQFIHEA 157
>UniRef50_Q7VFV4 Cluster: Malate dehydrogenase; n=1; Helicobacter
hepaticus|Rep: Malate dehydrogenase - Helicobacter
hepaticus
Length = 315
Score = 57.2 bits (132), Expect = 4e-07
Identities = 34/162 (20%), Positives = 78/162 (48%), Gaps = 1/162 (0%)
Frame = +2
Query: 221 QVSVIGAASDIGSYVSLFLKRNSKVSKLHLYDDD-DRIKGTELELSNLPGGPSVSAFIGD 397
++++IG + ++GS+++ ++ L+ +D R KG L++S + I
Sbjct: 4 KIAIIGGSGNVGSHIAFLGAMRHIAKEILLFSNDIPRCKGVGLDISQAAAIFDIPILIKG 63
Query: 398 TNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAISTNP 577
N + I S +V++ + PR P TR +L NA +IQ + +A ++ + + +NP
Sbjct: 64 CNSYEEIAESEVVIITAGFPRTPNMTRNDLLLKNASIIQEISSNVARIAPQSLLIVVSNP 123
Query: 578 INYLIPFASTVMYKYGCYNPSKMFGITHIDTSRSRSFVAKAL 703
++ + V ++ + ++ G+ I S ++ +K +
Sbjct: 124 LDAM----CLVAKQWSKFEKERVIGMAGILDSARLTYESKVM 161
>UniRef50_Q64P62 Cluster: Malate dehydrogenase; n=28;
Bacteroidetes|Rep: Malate dehydrogenase - Bacteroides
fragilis
Length = 313
Score = 56.4 bits (130), Expect = 7e-07
Identities = 41/168 (24%), Positives = 91/168 (54%), Gaps = 3/168 (1%)
Frame = +2
Query: 221 QVSVIGAASDIGSYVSLFLKRNSKVSKLHLYDDDDRI-KGTELELSNLPGGPSV-SAFIG 394
+V+V+GA + +G+ + L N ++ + D + + +G +++ + +G
Sbjct: 3 KVTVVGAGN-VGATCANVLAFNEVADEVVMLDVKEGVSEGKAMDMMQTAQLLGFDTTIVG 61
Query: 395 DTNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAISTN 574
TN +S++VV+ S +PRKPG TRE+++G NA +++ + + + + A + + +N
Sbjct: 62 CTNDYAQTANSDVVVITSGIPRKPGMTREELIGVNAGIVKSVAENLLKYSPNAIIVVISN 121
Query: 575 PINYLIPFASTVMYKYGCYNPSKMFGI-THIDTSRSRSFVAKALKINA 715
P++ + A + G +++ G+ +D+SR + F+++AL NA
Sbjct: 122 PMDTMTYLA---LKSLG-LPKNRVIGMGGALDSSRFKYFLSQALGCNA 165
>UniRef50_A0RXX8 Cluster: Malate/L-lactate dehydrogenase; n=1;
Cenarchaeum symbiosum|Rep: Malate/L-lactate
dehydrogenase - Cenarchaeum symbiosum
Length = 302
Score = 55.6 bits (128), Expect = 1e-06
Identities = 36/161 (22%), Positives = 85/161 (52%), Gaps = 2/161 (1%)
Frame = +2
Query: 224 VSVIGAASDIGSYVSLFLKRNSKVSKLHLYDDDDRI-KGTELELSNLPGGPSVSAFIGDT 400
+++IGA +G ++F S++ L D + + +G ++++++ + + +
Sbjct: 2 ITIIGAGK-VGGDAAMFCALRRLDSEILLLDIVEGLPQGEAMDINHMLAEQGIDTEVRGS 60
Query: 401 NLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAISTNPI 580
N + S++VV+V+ RKPG TR +L NA +++ + + + +++ + TNP+
Sbjct: 61 NDYSDMEGSDIVVVVAGAGRKPGMTRMDLLKINAGIVKGVVEKVKEHAKDSMIIPVTNPL 120
Query: 581 NYLIPFASTVMYKYGCYNPSKMFGI-THIDTSRSRSFVAKA 700
+ + + + YK + +++FG+ +D SR R F+ +A
Sbjct: 121 DPI----TYIAYKTSGFEKNRVFGMGGMLDLSRFRQFIHEA 157
>UniRef50_UPI0000D56DC5 Cluster: PREDICTED: similar to Malate
dehydrogenase, mitochondrial precursor; n=1; Tribolium
castaneum|Rep: PREDICTED: similar to Malate
dehydrogenase, mitochondrial precursor - Tribolium
castaneum
Length = 349
Score = 55.2 bits (127), Expect = 2e-06
Identities = 29/159 (18%), Positives = 79/159 (49%)
Frame = +2
Query: 176 TQLKKNTLILQKRNVQVSVIGAASDIGSYVSLFLKRNSKVSKLHLYDDDDRIKGTELELS 355
T+ ++ +++VQV ++GA + +G ++ +K+N +S LHL +++ L+ +
Sbjct: 8 TKFSRHFCSKPQKHVQVCILGADTLLGQSLAFLIKQNPAISGLHL-QGTSKVESMALDFN 66
Query: 356 NLPGGPSVSAFIGDTNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIA 535
+ V ++ ++ +++ +++VVM+ + +++ A + +L + A
Sbjct: 67 HFDTRCRVHSYYDMDSVSKSVKCADIVVMLGLNTSTSKMSIPKLVMAEGVRVAKLAETCA 126
Query: 536 AQNQEAFVAISTNPINYLIPFASTVMYKYGCYNPSKMFG 652
+A + ++ PI+ +P + V + Y+P ++ G
Sbjct: 127 KYAPKAVIVVAVTPISVTLPIVAEVYKQSDWYHPGRLLG 165
>UniRef50_Q9PHY2 Cluster: Probable malate dehydrogenase; n=12;
Campylobacter|Rep: Probable malate dehydrogenase -
Campylobacter jejuni
Length = 300
Score = 54.4 bits (125), Expect = 3e-06
Identities = 40/166 (24%), Positives = 85/166 (51%), Gaps = 2/166 (1%)
Frame = +2
Query: 218 VQVSVIGAASDIGSYVSLFLKRNSKVSKLHLYD-DDDRIKGTELELSNLPGGPSVSAFIG 394
++++VIGA + +GS V+ L +++ L D ++D + ELEL+ +++ +
Sbjct: 1 MKITVIGAGN-VGSSVAYALILREIANEIVLVDINEDLLYAKELELTQSIAALNLNIDLL 59
Query: 395 DTNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAISTN 574
T +S++V+ + RK G +RE++L N ++ K I ++ I TN
Sbjct: 60 CTKDYTHTKNSDIVLFSAGFARKDGQSREELLQLNTSIMLDCAKKIKDFTEDPLFIILTN 119
Query: 575 PINYLIPFASTVMYKYGCYNPSKMFGITHI-DTSRSRSFVAKALKI 709
P+++L+ +Y+ G ++ K+ + + D +R + +AK L +
Sbjct: 120 PVDFLL----NTLYESGIFSSKKIIAMAGVLDNARFKYELAKKLNV 161
>UniRef50_Q8YJE7 Cluster: Malate dehydrogenase; n=98; Bacteria|Rep:
Malate dehydrogenase - Brucella melitensis
Length = 320
Score = 54.4 bits (125), Expect = 3e-06
Identities = 41/168 (24%), Positives = 85/168 (50%), Gaps = 2/168 (1%)
Frame = +2
Query: 221 QVSVIGAASDIGSYVSLF-LKRNSKVSKLHLYDDDDRIKGTELELSNLPGGPSVSAFIGD 397
++++IG+ G+ L LK V + + + KG ++ S+ G F G
Sbjct: 5 KIALIGSGMIGGTLAHLAGLKELGDVVLFDIAEGTPQGKGLDIAESSPVDGFDAK-FTG- 62
Query: 398 TNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAISTNP 577
N AI +++V++ + +PRKPG +R+ +LG N +++++ I EAFV TNP
Sbjct: 63 ANDYAAIEGADVVIVTAGVPRKPGMSRDDLLGINLKVMEQVGAGIKKYAPEAFVICITNP 122
Query: 578 INYLIPFASTVMYKYGCYNPSKMFGITHI-DTSRSRSFVAKALKINAQ 718
++ ++ + K+ K+ G+ + D++R R F+++ ++ +
Sbjct: 123 LDAMV----WALQKFSGLPAHKVVGMAGVLDSARFRYFLSEEFNVSVE 166
>UniRef50_O67655 Cluster: Malate dehydrogenase 1; n=3; Bacteria|Rep:
Malate dehydrogenase 1 - Aquifex aeolicus
Length = 335
Score = 54.4 bits (125), Expect = 3e-06
Identities = 42/177 (23%), Positives = 89/177 (50%), Gaps = 14/177 (7%)
Frame = +2
Query: 224 VSVIGAASDIGSYVS--LFLKRNSKVSKLHLYDDDDR-----IKGTELELSNLPGGPSVS 382
V+VIGA + +G +V+ + LK + V L + +KG L++ + +
Sbjct: 7 VAVIGAGN-VGEHVASLILLKNLANVKMFDLPRKTEEKVFEPVKGKALDMKQMLAAMDID 65
Query: 383 AFIGDTNLE------QAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQN 544
A + + + + S++VV+ + PR+PG +RE +L AN +I + I
Sbjct: 66 ARVEGYTVTPEGEGYEPLEGSDIVVITAGFPRRPGMSREDLLEANIRIISVIADRIKRYA 125
Query: 545 QEAFVAISTNPINYLIPFASTVMYKYGCYNPSKMFGITHI-DTSRSRSFVAKALKIN 712
+A V + TNP++ + + V YK + +++ G+ + D++R ++F+++ L ++
Sbjct: 126 PDAIVIVVTNPVDVM----TYVAYKLLNFPKNRVMGMAGVLDSARFKTFISEELMVS 178
>UniRef50_A7U552 Cluster: Mitochondrial malate-dehydrogenase; n=2;
Toxoplasma gondii|Rep: Mitochondrial
malate-dehydrogenase - Toxoplasma gondii
Length = 470
Score = 54.0 bits (124), Expect = 4e-06
Identities = 41/166 (24%), Positives = 89/166 (53%), Gaps = 2/166 (1%)
Frame = +2
Query: 221 QVSVIGAASDIGSYVSLFLKRNSKVSKLHLYDD-DDRIKGTELELSNLPGGPSVSAFIGD 397
++ +IG + IG+ ++L L ++ + ++D D +G L+L L V
Sbjct: 159 KIGLIGGGN-IGATLAL-LSAVKELGDVVMFDVVQDLPQGKCLDLYQLTPISGVDVRFEG 216
Query: 398 TNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAISTNP 577
+N + ++++++ + +PRKPG +R+ +L NA ++ ++ +AI AFV TNP
Sbjct: 217 SNDYSVLKDADVIIVTAGVPRKPGMSRDDLLAINAKIMGQVGEAIKQYCPNAFVICITNP 276
Query: 578 INYLIPFASTVMYKYGCYNPSKMFGITHI-DTSRSRSFVAKALKIN 712
++ ++ + K G P K+ G+ + D++R R+F+++ L ++
Sbjct: 277 LDVMV---YILREKCG-LPPHKVCGMAGVLDSARLRTFLSERLNVS 318
>UniRef50_P59390 Cluster: L-lactate dehydrogenase 2; n=8;
Lactobacillus|Rep: L-lactate dehydrogenase 2 -
Lactobacillus plantarum
Length = 309
Score = 54.0 bits (124), Expect = 4e-06
Identities = 41/174 (23%), Positives = 88/174 (50%), Gaps = 5/174 (2%)
Frame = +2
Query: 203 LQKRNVQVSVIGAASDIGSYVSLFLKRNSKVSKLHLYDDDDRIKGTELELSNLPGGPSVS 382
+ K+ +V ++G S +GS + L +N + +L + D + T E ++ V+
Sbjct: 1 MDKKQRKVVIVGDGS-VGSSFAFSLVQNCALDELVIVD----LVKTHAE-GDVKDLEDVA 54
Query: 383 AFIGDTNLEQAIHS----SNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQE 550
AF TN+ ++ +++VV+ + +PRKPG +R ++ N +++ + K + A
Sbjct: 55 AFTNATNIHTGEYADARDADIVVITAGVPRKPGESRLDLINRNTKILESIVKPVVASGFN 114
Query: 551 AFVAISTNPINYLIPFASTVMYKYGCYNPSKMFGI-THIDTSRSRSFVAKALKI 709
IS+NP++ L +++ + + ++ G T +DT+R R +A+ L +
Sbjct: 115 GCFVISSNPVDIL----TSMTQRLSGFPRHRVIGTGTSLDTARLRVALAQKLNV 164
>UniRef50_UPI00015B5ACF Cluster: PREDICTED: similar to
ENSANGP00000020184; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ENSANGP00000020184 - Nasonia
vitripennis
Length = 352
Score = 53.6 bits (123), Expect = 5e-06
Identities = 42/179 (23%), Positives = 88/179 (49%), Gaps = 10/179 (5%)
Frame = +2
Query: 212 RNVQVSVIGAASDIGSYVSLFLKRNSKVSKLHLYDDDDRIKGTELELSNLPG-------- 367
RN++V+++GA G ++L LK+++ + +L +YD +G LELS++
Sbjct: 34 RNLKVAIVGATGQTGRSLALCLKQSALIDELAVYDSHP-TRGLLLELSHMDSRCRTIVED 92
Query: 368 -GPSVSAFIGDTNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQN 544
+ SA G +LE+A+ + +V + + RE+ A ++++ +
Sbjct: 93 EASTTSACNGKRDLERALTGAKIVAIT----LDGESIREE-----AEYLEKILSGLLGCC 143
Query: 545 QEAFVAISTNPINYLIPFASTVMYKYGCYN-PSKMFGITHIDTSRSRSFVAKALKINAQ 718
+A VA+ + +N L+P + + G + S++FG+ + +R+ A+ LKI +
Sbjct: 144 PKALVALVSRRVNSLVPMLYELYKRAGLFEASSRIFGVVSLFATRANGLAAETLKIQPE 202
>UniRef50_Q7M9A7 Cluster: Malate dehydrogenase; n=4;
Epsilonproteobacteria|Rep: Malate dehydrogenase -
Wolinella succinogenes
Length = 314
Score = 53.6 bits (123), Expect = 5e-06
Identities = 38/162 (23%), Positives = 79/162 (48%), Gaps = 2/162 (1%)
Frame = +2
Query: 224 VSVIGAASDIGSYVSLFLKRNSKVSKLHLYDDD-DRIKGTELELSNLPGGPSVSAFIGDT 400
+ +IGA +GS V+ L ++ + D + D +G L++ + +
Sbjct: 1 MGIIGAGH-VGSTVAFILATQGICQEIIIKDLNLDTARGIALDMGHAASATKTHTIVRVA 59
Query: 401 NLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAISTNPI 580
N + ++VV + PR+PG +R+ +L ANA +I+ + + QE+ + + +NP+
Sbjct: 60 NEPSDLRGCDVVVFCAGSPRQPGMSRDDLLLANAKVIRTVLSEVKPYIQESVLVMVSNPL 119
Query: 581 NYLIPFASTVMYKYGCYNPSKMFGITHI-DTSRSRSFVAKAL 703
+ ++ A K +P ++ G+ I D++R SF+ + L
Sbjct: 120 DAMVYTA----IKESGLSPLQVLGMAGILDSARMASFIFEKL 157
>UniRef50_P11386 Cluster: Malate dehydrogenase; n=6;
Sulfolobaceae|Rep: Malate dehydrogenase - Sulfolobus
acidocaldarius
Length = 306
Score = 53.6 bits (123), Expect = 5e-06
Identities = 44/167 (26%), Positives = 78/167 (46%), Gaps = 1/167 (0%)
Frame = +2
Query: 218 VQVSVIGAASDIGSYVSLFLKRNSKVSKLHLYDDDDRI-KGTELELSNLPGGPSVSAFIG 394
V+V+ IG +G ++ N ++ LYD + + E E+ + V +
Sbjct: 2 VKVAFIGVGR-VGQTIAYNTIVNGYADEVMLYDVVPELPEKFEHEIRHALAALRVKTELL 60
Query: 395 DTNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAISTN 574
TN I +++VV+ + PRKPG +R + NA ++ L K + +N+ A + N
Sbjct: 61 STNNIDDISGADIVVITAGKPRKPGMSRRDLFIDNAKIMIDLAKKLPKKNKGAMYIMVAN 120
Query: 575 PINYLIPFASTVMYKYGCYNPSKMFGITHIDTSRSRSFVAKALKINA 715
P++ + ++V KY N ++T R RS++AK L I A
Sbjct: 121 PVDMM----ASVFMKYSGENTISTG--NQVETMRMRSYIAKKLNIPA 161
>UniRef50_A4L2P0 Cluster: L-lactate dehydrogenase; n=4;
Lactobacillus|Rep: L-lactate dehydrogenase -
Lactobacillus reuteri
Length = 312
Score = 53.2 bits (122), Expect = 6e-06
Identities = 42/167 (25%), Positives = 83/167 (49%), Gaps = 3/167 (1%)
Frame = +2
Query: 221 QVSVIGAASDIGSYVSLFLKRNSKVSKLHLYD-DDDRIKGTELELSNL-PGGPSVSAFIG 394
+V +IG + S+ FL+ ++V +L L D + G +L+++ P V + G
Sbjct: 8 KVVLIGDGAVGSSFAFSFLQSTNEVDELVLVDRTKSKAVGDAADLADITPLTNPVKIYAG 67
Query: 395 DTNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAISTN 574
E A +++VV+ + +PRKPG TR ++ N +++ + K I IS+N
Sbjct: 68 --TYEDAA-DADVVVITAGIPRKPGETRLDLVNKNTTILKSIIKPIVKSGFTGVFVISSN 124
Query: 575 PINYLIPFASTVMYKYGCYNPSKMFGI-THIDTSRSRSFVAKALKIN 712
P++ L +T+ + + ++ G T +D+ R R ++K L ++
Sbjct: 125 PVDIL----TTIAQRISGFPKERVIGTGTSLDSMRLRVLLSKKLHLS 167
>UniRef50_Q18WQ6 Cluster: Malate dehydrogenase, NAD-dependent; n=2;
Desulfitobacterium hafniense|Rep: Malate dehydrogenase,
NAD-dependent - Desulfitobacterium hafniense (strain
DCB-2)
Length = 320
Score = 52.8 bits (121), Expect = 8e-06
Identities = 38/168 (22%), Positives = 85/168 (50%), Gaps = 2/168 (1%)
Frame = +2
Query: 221 QVSVIGAA-SDIGSYVSLFLKRNSKVSKLHLYDDDDRIKGTELELSNLPGGPSVSAFIGD 397
++SVIG+ + + L +K + L +++ KG L++ S +
Sbjct: 3 KISVIGSGFTGTTTAFMLAMKGLGDIVLLDTQANENPTKGKALDIMEAGPLTRSSVRVTG 62
Query: 398 TNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAISTNP 577
T+ Q S++VV+ + + RKPG +R ++ NA ++ + + + + + + I +NP
Sbjct: 63 TSDYQDTLDSDVVVITAGIARKPGMSRNELCDINAGIVTHVVRQVVQHSPNSTLIILSNP 122
Query: 578 INYLIPFASTVMYKYGCYNPSKMFGITHI-DTSRSRSFVAKALKINAQ 718
++ + + V +K + +++ G + + D++R R FVA LK++A+
Sbjct: 123 VDIM----TYVAFKESGFKRNRIIGQSGVLDSARFRYFVASELKVSAE 166
>UniRef50_A1U9V0 Cluster: Lactate/malate dehydrogenase; n=6;
Actinomycetales|Rep: Lactate/malate dehydrogenase -
Mycobacterium sp. (strain KMS)
Length = 329
Score = 52.8 bits (121), Expect = 8e-06
Identities = 45/166 (27%), Positives = 81/166 (48%), Gaps = 3/166 (1%)
Frame = +2
Query: 221 QVSVIGAASDIGSYVSLFLKRNSKVSKLHLYDDDD-RIKGTELELSNLPGGPSV-SAFIG 394
+VS+IGA S +G+ ++ L LYD + +++ L+L++ G V +G
Sbjct: 20 KVSIIGAGS-VGTAIAYACLIRGSAGTLALYDTNSAKVRAEVLDLNH--GSQFVPECRVG 76
Query: 395 DTNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAISTN 574
++ S +VV+ + + PG +R + AN + Q L + + +A V TN
Sbjct: 77 GSDDIAVTAGSAIVVVTAGAKQHPGQSRLDLAAANVAMAQTLTPQLLEHSPDAVVIFVTN 136
Query: 575 PINYLIPFASTVMYKYGCYNPSKMFGI-THIDTSRSRSFVAKALKI 709
P++ + AS+V+ P ++FG T +D+SR R VA+ I
Sbjct: 137 PVDVVTYAASSVVDA----QPGQIFGTGTVLDSSRFRYLVAQRAAI 178
>UniRef50_Q6LZI3 Cluster: Malate dehydrogenase; n=5;
Methanococcus|Rep: Malate dehydrogenase - Methanococcus
maripaludis
Length = 314
Score = 52.8 bits (121), Expect = 8e-06
Identities = 44/172 (25%), Positives = 89/172 (51%), Gaps = 7/172 (4%)
Frame = +2
Query: 218 VQVSVIGAASDIGSYVSLFLKRNSKVSKLHLY---DDDDRIKGTELELSNLPGGPSVSAF 388
+ VS+IGA+ IGS +SL L + S + ++L +++KG +++L +
Sbjct: 1 MDVSIIGASGKIGSVLSLLLAKESHIKNINLIARSSSINKLKGLKMDLYDAMAAAGQDTD 60
Query: 389 IG---DTNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFV 559
I D +L +S++ ++ + M R +R ++ NA +++ K IA
Sbjct: 61 IDICCDDDL-SCTANSDITIITAGMARTGEMSRIDLMKGNAKIVKNYVKNIANFGDTKIF 119
Query: 560 AISTNPINYLIPFASTVMYKYGCYNPSKMFGI-THIDTSRSRSFVAKALKIN 712
IS NP++ L+ + + + + G Y +++FG+ TH+D+ R + VAK +++
Sbjct: 120 MIS-NPVD-LMTYKALI--ESG-YEKNQVFGLGTHLDSMRFKVAVAKHFEVH 166
>UniRef50_Q892U0 Cluster: L-lactate dehydrogenase; n=12;
Bacteria|Rep: L-lactate dehydrogenase - Clostridium
tetani
Length = 316
Score = 52.8 bits (121), Expect = 8e-06
Identities = 39/175 (22%), Positives = 87/175 (49%), Gaps = 3/175 (1%)
Frame = +2
Query: 203 LQKRNVQVSVIGAASDIGSYVSLFLKRNSKVSKLHLYD-DDDRIKGTELELSN-LPGGPS 376
+ K+ +++S+IG+ +GS + L S++ + D + ++ KG ++LS+ +
Sbjct: 1 MNKKGIKISIIGSGF-VGSTTAYALMMEGLASEIVIVDINKEKAKGEAMDLSHGVSFVKP 59
Query: 377 VSAFIGDTNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAF 556
V GD + S++V++ + KPG TR ++ N + + + + + ++
Sbjct: 60 VDIIAGDY---EDTKDSDIVIITAGAGPKPGETRLDLINKNYEIFKGIVPEVVKYSPKSI 116
Query: 557 VAISTNPINYLIPFASTVMYKYGCYNPSKMFGI-THIDTSRSRSFVAKALKINAQ 718
+ + +NP++ L + V YK + ++ G T +DTSR R + + KI+ +
Sbjct: 117 LLVVSNPVDIL----TYVTYKLSGFPQERVIGSGTVLDTSRFRYLLGEHFKIDVR 167
>UniRef50_Q5CYZ2 Cluster: Lactate dehydrogenase, adjacent gene
encodes predicted malate dehydrogenase; n=8;
Cryptosporidium|Rep: Lactate dehydrogenase, adjacent
gene encodes predicted malate dehydrogenase -
Cryptosporidium parvum Iowa II
Length = 337
Score = 52.4 bits (120), Expect = 1e-05
Identities = 42/168 (25%), Positives = 92/168 (54%), Gaps = 3/168 (1%)
Frame = +2
Query: 221 QVSVIGAASDIGSYVSLFLKRNSKVSKLHLYDDDDRI-KGTELELSN-LPGGPSVSAFIG 394
+++VIG+ IG ++ + +++ ++ + L+D + I +G L++++ + S S IG
Sbjct: 22 KIAVIGSGQ-IGGNIAYIVGKDN-LADVVLFDIAEGIPQGKALDITHSMVMFGSTSKVIG 79
Query: 395 DTNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAISTN 574
TN I S++V++ + +P +P + R ++L NA ++ + + + AFV TN
Sbjct: 80 -TNDYADISGSDVVIITASIPGRPKDDRSELLFGNARILDSVAEGVKKYCPNAFVICITN 138
Query: 575 PINYLIPFASTVMYKYGCYNPSKMFGITHI-DTSRSRSFVAKALKINA 715
P++ ++ + K +K+ G+ + D+SR R+F+A+ +NA
Sbjct: 139 PLDVMV----SHFQKVSGLPHNKVCGMAGVLDSSRFRTFIAQHFGVNA 182
>UniRef50_Q7NHJ3 Cluster: Malate dehydrogenase; n=13; cellular
organisms|Rep: Malate dehydrogenase - Gloeobacter
violaceus
Length = 325
Score = 52.4 bits (120), Expect = 1e-05
Identities = 40/162 (24%), Positives = 81/162 (50%), Gaps = 1/162 (0%)
Frame = +2
Query: 212 RNVQVSVIGAASDIGSYVSLFLKRNSKVSKLHLYDDDDRIKGTELELSNLPGGPSVSAFI 391
R +VS++GA + +GS ++ L + + + L + R +G L+L G + I
Sbjct: 7 RESKVSILGAGN-VGSALAQRLIQGNVADVVLLDIVEGRPQGITLDLLEACGVEGHTCRI 65
Query: 392 GDTNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAIST 571
TN S+++V+ + R+PG +R+ +L N ++ + + A + EA V + T
Sbjct: 66 TGTNDYAQTAGSDVLVVAAGFARQPGMSRDDLLLTNTRIVFEVTQKAVAHSPEATVVVVT 125
Query: 572 NPINYLIPFASTVMYKYGCYNPSKMFGITHI-DTSRSRSFVA 694
NP++ + S V ++ P ++ G+ + D +R +F+A
Sbjct: 126 NPLDAM----SHVAWRASGLVPERVMGMAGVLDAARFETFIA 163
>UniRef50_A5KJY5 Cluster: Putative uncharacterized protein; n=2;
Ruminococcus|Rep: Putative uncharacterized protein -
Ruminococcus torques ATCC 27756
Length = 316
Score = 52.0 bits (119), Expect = 1e-05
Identities = 37/171 (21%), Positives = 90/171 (52%), Gaps = 3/171 (1%)
Frame = +2
Query: 215 NVQVSVIGAASDIGSYVSLFLKRNSKVSKLHLYDDDD-RIKGTELELSN-LPGGPSVSAF 388
N+Q + + +GS ++ L + S++ L D + + +G +++S+ LP ++ +
Sbjct: 3 NIQKAAVIGCGFVGSTIAYTLMQKGLFSEMVLLDANKAKAEGEAMDISHGLPFTHAMDIY 62
Query: 389 IGDTNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAIS 568
G+ + I +++V++ + +KPG TR ++ NA +++ + K I N E + I
Sbjct: 63 AGEY---EDIADASVVIITAGANQKPGETRLDLVQKNAAIMRSIIKEIKRVNCEGILLIV 119
Query: 569 TNPINYLIPFASTVMYKYGCYNPSKMFGI-THIDTSRSRSFVAKALKINAQ 718
+NP++ L + V + + ++ G T +DT+R + +++ L ++++
Sbjct: 120 SNPVDIL----TEVALRESGFPKERVIGSGTVLDTARLKYIISEKLDVDSR 166
>UniRef50_UPI00015B4591 Cluster: PREDICTED: similar to mitochondrial
malate dehydrogenase; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to mitochondrial malate dehydrogenase
- Nasonia vitripennis
Length = 299
Score = 51.2 bits (117), Expect = 2e-05
Identities = 31/150 (20%), Positives = 76/150 (50%), Gaps = 2/150 (1%)
Frame = +2
Query: 269 LFLKRNSKVSKLHLYDDDDRIKGTELELSNLPGGPSVSAFIGDTNLEQAIHSSNLVVMVS 448
+ LK+N + ++ L D D+ + ++ ++ ++ F ++ L+ + ++++V ++
Sbjct: 1 MLLKQNPAIKEIRLIDTDNSLMSPVCDMRHIDTSTTIRHFRKNSILD-GLRNTDIVALMD 59
Query: 449 RMPRKPGNTREQMLGANAP-LIQRLCKAIAAQNQEAFVAISTNPINYLIPFASTVMYKY- 622
GN M N+ ++ + + + +A VA+ T+P+ +P S + YKY
Sbjct: 60 ETDFMMGNKGPFMQFVNSSNYVKSVAECMINVCPKALVAVFTHPVTATLPLVSEI-YKYS 118
Query: 623 GCYNPSKMFGITHIDTSRSRSFVAKALKIN 712
G ++P+++FG +++ R + A L +N
Sbjct: 119 GDWDPNRIFGSAALESMRISAMTATLLDLN 148
>UniRef50_Q1IRL5 Cluster: L-lactate dehydrogenase; n=6;
Bacteria|Rep: L-lactate dehydrogenase - Acidobacteria
bacterium (strain Ellin345)
Length = 321
Score = 50.8 bits (116), Expect = 3e-05
Identities = 36/169 (21%), Positives = 84/169 (49%), Gaps = 2/169 (1%)
Frame = +2
Query: 218 VQVSVIGAASDIGSYVSLFLKRNSKVSKLHLYDDDDRIKGTELELSN-LPGGPSVSAFIG 394
++++V+G + S+ L+R + + + + +G ++L++ +P G + + G
Sbjct: 11 LRIAVVGLGNVGASFAFALLQRRLAAEIVLIDANHKKAEGEAMDLNHAVPFGAATRIWAG 70
Query: 395 DTNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAISTN 574
+ + + V+ + ++PG TR Q+L N + Q++ + N + + I+TN
Sbjct: 71 EY---ADCRGAAVTVITAGAAQRPGETRLQLLDRNLAIFQQIVPEVVKHNPDGLLLIATN 127
Query: 575 PINYLIPFASTVMYKYGCYNPSKMFGI-THIDTSRSRSFVAKALKINAQ 718
P++ +I +AS YK ++ G T +DT+R R + + ++A+
Sbjct: 128 PVD-IISYAS---YKISGLPAHRVLGSGTILDTARFRYLLGQHFSVDAR 172
>UniRef50_A4A2L6 Cluster: L-lactate dehydrogenase; n=4;
Bacteria|Rep: L-lactate dehydrogenase - Blastopirellula
marina DSM 3645
Length = 313
Score = 50.8 bits (116), Expect = 3e-05
Identities = 41/168 (24%), Positives = 84/168 (50%), Gaps = 4/168 (2%)
Frame = +2
Query: 218 VQVSVIGAASDIGSYVSLFLKRNSKVSKLHLYD-DDDRIKGTELELSNLPGGPSVSAFIG 394
++VS+IG +GS + L+ ++ L D + D G L+L L G PSV+ +
Sbjct: 1 MKVSIIGGGGLVGSCAAFALQCGGIAREIALLDLNADLAGGHALDL--LHGAPSVADQVI 58
Query: 395 DTNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAI--AAQNQEAFVAIS 568
+ + I S+++ + + + RKP +R ++ N L + ++ A ++A +
Sbjct: 59 TSGGYEHIPDSDVICITAGLRRKPDESRLDLINRNVDLFLSILDSVKSAGVKKDAICFVV 118
Query: 569 TNPINYLIPFASTVMYKYGCYNPSKMFGI-THIDTSRSRSFVAKALKI 709
+NP++ L A+ + S++ G+ T +DT R R+ +A+ +K+
Sbjct: 119 SNPVDILTYLAAQRLN----LPTSRVIGLGTQLDTIRFRALIAQEMKL 162
>UniRef50_A6Q7S2 Cluster: Malate dehydrogenase, NAD-dependent; n=1;
Sulfurovum sp. NBC37-1|Rep: Malate dehydrogenase,
NAD-dependent - Sulfurovum sp. (strain NBC37-1)
Length = 320
Score = 50.0 bits (114), Expect = 6e-05
Identities = 39/167 (23%), Positives = 77/167 (46%), Gaps = 2/167 (1%)
Frame = +2
Query: 221 QVSVIGAASDIGSYVSLFLKRNSKVSKLHLYDDD-DRIKGTELELSNLPGGPSVSAFIGD 397
+V+VIG + GS V+ L N + L + D KG L++S +
Sbjct: 6 KVTVIGTGN-FGSTVAFILAMNGSCHHVMLRGRNYDVAKGKALDMSQAANAARQHTIVKA 64
Query: 398 TNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAISTNP 577
+ + S++V++ + PR PG +R+ +L NA +++ + I +A V + +NP
Sbjct: 65 AKGPEDMEGSDVVIITAGAPRTPGMSRDDLLFKNADIVKCYSREIKEYAPDAIVIVVSNP 124
Query: 578 INYLIPFASTVMYKYGCYNPSKMFGITHI-DTSRSRSFVAKALKINA 715
++ + + V K + ++ G+ I D +R F+ + L+ A
Sbjct: 125 LDVM----TYVALKETGFPRQRVLGMAGILDAARMAHFIYEKLEYGA 167
>UniRef50_O51114 Cluster: L-lactate dehydrogenase; n=4; Borrelia
burgdorferi group|Rep: L-lactate dehydrogenase -
Borrelia burgdorferi (Lyme disease spirochete)
Length = 316
Score = 50.0 bits (114), Expect = 6e-05
Identities = 40/170 (23%), Positives = 88/170 (51%), Gaps = 4/170 (2%)
Frame = +2
Query: 221 QVSVIGAASDIGSYVSLFLKRNSKVSKLHLYD-DDDRIKGTELELSN--LPGGPSVSAFI 391
+V +IGA S+ NS V +L + D ++++ KG ++L++ + +++
Sbjct: 6 KVVLIGAGGVGSSFAYALTIDNSLVHELVIIDVNENKAKGEVMDLNHGQMFLKKNINVLF 65
Query: 392 GDTNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAIST 571
G T + A ++++VV+ + + +KPG TR ++ N+ + + + + + + +++
Sbjct: 66 G-TYKDCA--NADIVVITAGLNQKPGETRLDLVDKNSKIFKDIITNVVSSGFDGIFVVAS 122
Query: 572 NPINYLIPFASTVMYKYGCYNPSKMFGI-THIDTSRSRSFVAKALKINAQ 718
NP++ + + V KY + K+ G T +DTSR R F++ +N Q
Sbjct: 123 NPVDIM----TYVTMKYSKFPIHKVIGTGTILDTSRLRYFLSDHFNVNTQ 168
>UniRef50_Q5LXE1 Cluster: Malate dehydrogenase; n=115; cellular
organisms|Rep: Malate dehydrogenase - Silicibacter
pomeroyi
Length = 320
Score = 49.2 bits (112), Expect = 1e-04
Identities = 35/166 (21%), Positives = 84/166 (50%), Gaps = 2/166 (1%)
Frame = +2
Query: 221 QVSVIGAASDIGSYVSLFLKRNSKVSKLHLYD-DDDRIKGTELELSNLPGGPSVSAFIGD 397
++++IGA G+ L + ++ + L+D + +G L+++ A +
Sbjct: 5 KIALIGAGQIGGTLAHLVALK--ELGDVVLFDIAEGTPEGKALDIAESGPSEGFDAKLKG 62
Query: 398 TNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAISTNP 577
T I +++ ++ + +PRKPG +R+ +LG N +++ + + I +AFV TNP
Sbjct: 63 TQSYADIAGADVCIVTAGVPRKPGMSRDDLLGINLKVMKSVGEGIRDNAPDAFVICITNP 122
Query: 578 INYLIPFASTVMYKYGCYNPSKMFGITHI-DTSRSRSFVAKALKIN 712
++ ++ + ++ +K+ G+ + D++R R F+A+ ++
Sbjct: 123 LDAMV----WALQQFSGLPANKVCGMAGVLDSARFRHFLAEEFNVS 164
>UniRef50_Q07841 Cluster: Malate dehydrogenase; n=7;
Halobacteriaceae|Rep: Malate dehydrogenase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 304
Score = 49.2 bits (112), Expect = 1e-04
Identities = 37/159 (23%), Positives = 79/159 (49%), Gaps = 5/159 (3%)
Frame = +2
Query: 221 QVSVIGAASDIGSYVSLFLKRNSKVSKLHLYDDDDRIKGTELELSNLPGGPSVSAFIGDT 400
+VSV+GAA +G+ + ++ D D+ T + ++ G A+ +T
Sbjct: 3 KVSVVGAAGTVGAAAGYNIALRDIADEVVFVDIPDKEDDTVGQAADTNHG---IAYDSNT 59
Query: 401 NLEQAIHS----SNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAIS 568
+ Q + S++VV+ + +PR+PG TR + G NAP+++ + ++ N + +
Sbjct: 60 RVRQGGYEDTAGSDVVVITAGIPRQPGQTRIDLAGDNAPIMEDIQSSLDEHNDDYISLTT 119
Query: 569 TNPINYLIPFASTVMYKYGCYNPSKMFGI-THIDTSRSR 682
+NP++ L + +Y+ G + ++ G +D++R R
Sbjct: 120 SNPVDLL----NRHLYEAGDRSREQVIGFGGRLDSARFR 154
>UniRef50_Q9P7P7 Cluster: Probable L-lactate dehydrogenase; n=2;
Ascomycota|Rep: Probable L-lactate dehydrogenase -
Schizosaccharomyces pombe (Fission yeast)
Length = 330
Score = 49.2 bits (112), Expect = 1e-04
Identities = 35/172 (20%), Positives = 86/172 (50%), Gaps = 3/172 (1%)
Frame = +2
Query: 212 RNVQVSVIGAASDIGSYVSLFLKRNSKVSKLHLYD-DDDRIKGTELELSNL-PGGPSVSA 385
+++++ ++GA + +GS + L + +++ + D + + +G ++L++ P
Sbjct: 19 KSIKIVIVGAGN-VGSTTAFTLLLSGLAAEIVIIDLNKKKAEGEAMDLNHAAPLSHETRV 77
Query: 386 FIGDTNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAI 565
++GD + + VV+ + +KPG TR +L AN + + + + + ++A + +
Sbjct: 78 YLGDY---KDCKDATAVVITAGKNQKPGETRMDLLKANISIFKEILREVTKYTKDAILLV 134
Query: 566 STNPINYLIPFASTVMYKYGCYNPSKMFGI-THIDTSRSRSFVAKALKINAQ 718
+TNP++ L + K + ++ G T IDT+R + + K ++ Q
Sbjct: 135 ATNPVDVL----TYATLKLTGFPAERVIGSGTIIDTARFQYLIGKLYGLDPQ 182
>UniRef50_Q03BE6 Cluster: L-lactate dehydrogenase; n=1;
Lactobacillus casei ATCC 334|Rep: L-lactate
dehydrogenase - Lactobacillus casei (strain ATCC 334)
Length = 312
Score = 48.4 bits (110), Expect = 2e-04
Identities = 25/98 (25%), Positives = 54/98 (55%)
Frame = +2
Query: 425 SNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAISTNPINYLIPFAS 604
++++V+ + + +KPG TR Q+L NA +++ + I A F+ +++NP++ L A
Sbjct: 72 ADIIVITAGIAQKPGQTRLQLLAINAKIMKEITHNIMASGFNGFILVASNPVDVL---AE 128
Query: 605 TVMYKYGCYNPSKMFGITHIDTSRSRSFVAKALKINAQ 718
V+ + G + T +D++R RS + ++A+
Sbjct: 129 LVLQESGLPRNQVLGSGTALDSARLRSEIGLRYNVDAR 166
>UniRef50_A3EWH3 Cluster: Malate/lactate dehydrogenase; n=1;
Leptospirillum sp. Group II UBA|Rep: Malate/lactate
dehydrogenase - Leptospirillum sp. Group II UBA
Length = 320
Score = 48.4 bits (110), Expect = 2e-04
Identities = 39/167 (23%), Positives = 85/167 (50%), Gaps = 4/167 (2%)
Frame = +2
Query: 209 KRNVQVSVIGAASDIGSYVSLFLKRNSKVSKLHLYDDDDRIKGTELELSNLPGGPSV--- 379
++ +VS++GA + +G+ + + N + L + +G L++ L GP +
Sbjct: 4 RKRRKVSIVGAGN-VGATTAQKIVENGLADVVILDVREGMAQGKALDI--LESGPLLGFD 60
Query: 380 SAFIGDTNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFV 559
+ +G N E I S++VV+ + RKPG +RE +L N ++ + + I ++ V
Sbjct: 61 TRIVGSGNYE-TIEGSSVVVVTAGFSRKPGMSREDLLHKNGDIMIEVAEKIRKHAPDSVV 119
Query: 560 AISTNPINYLIPFASTVMYKYGCYNPSKMFGI-THIDTSRSRSFVAK 697
+ TNP++ + + +++K + ++ G+ +D+SR FV++
Sbjct: 120 IMVTNPMDLM----AYILWKVTGFPRERVIGMGGALDSSRFAYFVSE 162
>UniRef50_Q8XP62 Cluster: L-lactate dehydrogenase; n=11;
Clostridium|Rep: L-lactate dehydrogenase - Clostridium
perfringens
Length = 317
Score = 48.4 bits (110), Expect = 2e-04
Identities = 38/176 (21%), Positives = 87/176 (49%), Gaps = 2/176 (1%)
Frame = +2
Query: 197 LILQKRNVQVSVIGAASDIGSYVSLFLKRNSKVSKLHLYD-DDDRIKGTELELSNLPGGP 373
+I +K N ++S+IGA +GS + L ++ S++ + D + D+ ++L+ G
Sbjct: 1 MIREKTN-KISIIGAGF-VGSTTAFALMQDGLASEIVIVDINKDKAHAEAMDLAQ--GAA 56
Query: 374 SVSAFIGDTNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEA 553
V + + S++V++ + + KPG TR ++ N + Q + + + +
Sbjct: 57 FVKSVDIKSGDYADTKDSDIVIITAGVGPKPGETRLDIINKNLKIFQSIVPEVVKYSPNS 116
Query: 554 FVAISTNPINYLIPFASTVMYKYGCYNPSKMFGI-THIDTSRSRSFVAKALKINAQ 718
+ + +NP++ L + + YK + ++ G T +DTSR + +++ I+A+
Sbjct: 117 ILLVVSNPVDIL----TYITYKLSGFPKERVIGSGTVLDTSRLKYMLSEHFDIDAR 168
>UniRef50_Q6A9C3 Cluster: L-lactate dehydrogenase; n=2;
Propionibacterium acnes|Rep: L-lactate dehydrogenase -
Propionibacterium acnes
Length = 319
Score = 48.0 bits (109), Expect = 2e-04
Identities = 45/169 (26%), Positives = 83/169 (49%), Gaps = 5/169 (2%)
Frame = +2
Query: 191 NTLILQKRNVQVSVIGAASDIGSYVSLFLKRNSKVSKLHLYD-DDDRIKGTELELSNLPG 367
+T +R ++SV+GA S +GS ++ + LYD D++ E E+++L
Sbjct: 2 STFDATRRASKISVVGAGS-VGSSLAYACLIRGSAGLVSLYDIAKDKV---EAEVADLAH 57
Query: 368 GPSVS--AFIGDTNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQ 541
G + + +G ++ S++V + + +KPG TR + G NA +++ L + Q
Sbjct: 58 GTQFTPASVMGGADVHDTA-DSDVVFITAGARQKPGQTRLDLAGVNANILRSLMPQLVEQ 116
Query: 542 NQEAFVAISTNPINYLIPFASTVMYKYGCYNP-SKMFGI-THIDTSRSR 682
+ A + TNP + L TV+ + P +++F T +DTSR R
Sbjct: 117 SPNALFVLVTNPCDVL-----TVVAQEATGLPANRVFSTGTMLDTSRLR 160
>UniRef50_Q7UY63 Cluster: L-lactate/malate dehydrogenase; n=2;
Planctomycetaceae|Rep: L-lactate/malate dehydrogenase -
Rhodopirellula baltica
Length = 304
Score = 47.2 bits (107), Expect = 4e-04
Identities = 40/170 (23%), Positives = 87/170 (51%), Gaps = 3/170 (1%)
Frame = +2
Query: 218 VQVSVIGAASDIGSYVSLFLKRNSKVSKLHLYDDD-DRIKGTELELSNLPGGPSVSAFIG 394
++++++G +GS ++ L N S+L L + ++ +G L+L++ + I
Sbjct: 1 MKITLVGTGR-VGSAIAFALTINPLASELLLLNRSREKAEGDALDLTHAAALVDSNIKIS 59
Query: 395 DTNLEQAIHSSNLVVMVSRMP-RKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAIST 571
+ + S++++ + +P R P TR +M N P+++ +A + A V + +
Sbjct: 60 SGEIADS-KDSDVIIFTASVPFRYPNQTRLEMGIDNMPILRDWMPGLAKASPNAIVVMVS 118
Query: 572 NPINYLIPFASTVMYKYGCYNPSKMFGI-THIDTSRSRSFVAKALKINAQ 718
NP++ L A + G ++P ++ G T +D+ R R+ ++ LKI+AQ
Sbjct: 119 NPVDAL---AYETIRLTG-FDPKRVIGTGTLVDSIRYRALLSTELKIHAQ 164
>UniRef50_Q6F0L9 Cluster: L-lactate dehydrogenase; n=6;
Mollicutes|Rep: L-lactate dehydrogenase - Mesoplasma
florum (Acholeplasma florum)
Length = 317
Score = 46.8 bits (106), Expect = 5e-04
Identities = 26/96 (27%), Positives = 54/96 (56%), Gaps = 1/96 (1%)
Frame = +2
Query: 425 SNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAISTNPINYLIPFAS 604
++L+V+ + P++PG TR +++ N+ +++ + +AI A I++NP + L +
Sbjct: 74 ADLIVITAGRPQRPGETRLELIADNSRIMKGIAEAIKASGFNGVTVIASNPCDVL----T 129
Query: 605 TVMYKYGCYNPSKMFGI-THIDTSRSRSFVAKALKI 709
TV + Y+ + G T +D++R R VA+ L +
Sbjct: 130 TVYQQVTGYDEHSVVGAGTTLDSARLRRLVAEKLNV 165
>UniRef50_O08349 Cluster: Malate dehydrogenase; n=1; Archaeoglobus
fulgidus|Rep: Malate dehydrogenase - Archaeoglobus
fulgidus
Length = 294
Score = 46.0 bits (104), Expect = 0.001
Identities = 36/156 (23%), Positives = 76/156 (48%), Gaps = 3/156 (1%)
Frame = +2
Query: 218 VQVSVIGAASDIGSYVSLFLKRNSKVSKLHLYD-DDDRIKGTELELSNLPGG-PSVSAFI 391
+++ +GA +GS + N V ++ L D +D G ++L++ G +
Sbjct: 1 MKLGFVGAGR-VGSTSAFTCLLNLDVDEIALVDIAEDLAVGEAMDLAHAAAGIDKYPKIV 59
Query: 392 GDTNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAIST 571
G + + S ++V+ + + RKPG TR + NA +I+ + K I E+ + + T
Sbjct: 60 GGADYS-LLKGSEIIVVTAGLARKPGMTRLDLAHKNAGIIKDIAKKIVENAPESKILVVT 118
Query: 572 NPINYLIPFASTVMYKYGCYNPSKMFGI-THIDTSR 676
NP++ + + +M+K +++FG+ +D+ R
Sbjct: 119 NPMDVM----TYIMWKESGKPRNEVFGMGNQLDSQR 150
>UniRef50_O67581 Cluster: Malate dehydrogenase 2; n=1; Aquifex
aeolicus|Rep: Malate dehydrogenase 2 - Aquifex aeolicus
Length = 334
Score = 45.6 bits (103), Expect = 0.001
Identities = 23/102 (22%), Positives = 58/102 (56%), Gaps = 1/102 (0%)
Frame = +2
Query: 410 QAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAISTNPINYL 589
+ + S++VV+ + +PR+ G +RE +L N ++++ AI +++ + + +NP++ L
Sbjct: 84 EELKGSDIVVITAGIPRREGMSREDLLYENLKILKKFTDAIKEYAKDSIIIVVSNPVDTL 143
Query: 590 IPFASTVMYKYGCYNPSKMFGITHI-DTSRSRSFVAKALKIN 712
+ K + P ++ G+ + D++R ++FV + + I+
Sbjct: 144 ----TYATIKLTGFEPRRVIGMAGVLDSARFKNFVKEKIGIS 181
>UniRef50_Q6KIP9 Cluster: L-lactate dehydrogenase; n=1; Mycoplasma
mobile|Rep: L-lactate dehydrogenase - Mycoplasma mobile
Length = 318
Score = 45.6 bits (103), Expect = 0.001
Identities = 35/173 (20%), Positives = 83/173 (47%), Gaps = 3/173 (1%)
Frame = +2
Query: 203 LQKRNVQVSVIGAASDIGSYVSLFLKRNSKVSKLHLYDDDDRIK-GTELELSNLPGGPSV 379
+ K+ +V+++GA +G V + + D +D++ G L+ + +
Sbjct: 1 MDKKIKRVAMVGAGL-VGVSVLYSCMNRGLAEQYGIIDINDKLSVGHSLDFEDASAANNH 59
Query: 380 SAFIGDTNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFV 559
+ +G + ++VV+ + P+KPG TR +M+ NA ++ + K I +
Sbjct: 60 NFSVGKIEYSD-LKDYDVVVITAGRPQKPGETRLEMVADNAKIMSNIAKNIKKSGFKGVS 118
Query: 560 AISTNPINYLIPFASTVMYKYGC-YNPSKMFGI-THIDTSRSRSFVAKALKIN 712
+ NP++ + T +Y++ ++ +++ T +D++R R ++K LK++
Sbjct: 119 IVVANPVDVM-----TFIYQHETGFDKNRVISSGTSLDSARLRFEISKKLKVH 166
>UniRef50_Q4Q7X6 Cluster: Cytosolic malate dehydrogenase, putative;
n=7; Eukaryota|Rep: Cytosolic malate dehydrogenase,
putative - Leishmania major
Length = 324
Score = 45.2 bits (102), Expect = 0.002
Identities = 47/171 (27%), Positives = 76/171 (44%), Gaps = 11/171 (6%)
Frame = +2
Query: 218 VQVSVIGAASDIGSYVSLFLKRNSKVS-----KLHLYDDDDRIK---GTELELSNLPGGP 373
V+V+V GAA IG + + R + + +L L D + +K G E EL + P
Sbjct: 4 VKVAVTGAAGQIGYALVPLIARGALLGPTTPVELRLLDIEPALKALAGVEAELEDC-AFP 62
Query: 374 SVSAFIGDTNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAA-QNQE 550
+ + + A + +M PRK G R+ +L NA + + +AIAA +
Sbjct: 63 LLDKVVVTADPRVAFDGVAIAIMCGAFPRKAGMERKDLLEMNARIFKEQGEAIAAVAASD 122
Query: 551 AFVAISTNP--INYLIPFASTVMYKYGCYNPSKMFGITHIDTSRSRSFVAK 697
V + NP N LI S G NP + +T +D +R+ S +A+
Sbjct: 123 CRVVVVGNPANTNALILLKSA----QGKLNPRHVTAMTRLDHNRALSLLAR 169
>UniRef50_Q3ZZJ7 Cluster: Malate dehydrogenase; n=5; cellular
organisms|Rep: Malate dehydrogenase - Dehalococcoides
sp. (strain CBDB1)
Length = 307
Score = 45.2 bits (102), Expect = 0.002
Identities = 39/165 (23%), Positives = 77/165 (46%), Gaps = 1/165 (0%)
Frame = +2
Query: 221 QVSVIGAASDIGSYVSLFLKRNSKVSKLHLYDDDDRIKGTELELSNLPGGPSVSAFIGDT 400
++SVIGA + +G+ ++ L + L + +G L++S I +
Sbjct: 3 KISVIGAGN-VGATLAQRLIEKDFADVVMLDVVEGIPQGKALDISQSASVLGFRHTITGS 61
Query: 401 NLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAISTNPI 580
N S +VV+ + + RKPG TRE++L N ++ + + EA + + +NP+
Sbjct: 62 NDYAQTAGSEIVVITAGIARKPGMTREELLAINQKIMTDVVSNCLKYSPEATLVVVSNPV 121
Query: 581 NYLIPFASTVMYKYGCYNPSKMFGITHI-DTSRSRSFVAKALKIN 712
+ + A +K ++ G++ + D R +FVA+ L +N
Sbjct: 122 DTMTYLA----WKLSGLPRKRVVGLSGVLDGGRLATFVARELGVN 162
>UniRef50_A0LRV1 Cluster: Lactate/malate dehydrogenase; n=3;
Actinomycetales|Rep: Lactate/malate dehydrogenase -
Acidothermus cellulolyticus (strain ATCC 43068 / 11B)
Length = 330
Score = 44.8 bits (101), Expect = 0.002
Identities = 27/100 (27%), Positives = 51/100 (51%)
Frame = +2
Query: 410 QAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAISTNPINYL 589
+ I +++V++ + +PRKPG +R +L NA +++ + + IA A V + +NP++ +
Sbjct: 83 EVIADASIVIITAGVPRKPGMSRMDLLETNARIVRGVAENIAKYAPSAVVIVVSNPLDEM 142
Query: 590 IPFASTVMYKYGCYNPSKMFGITHIDTSRSRSFVAKALKI 709
V G M +DT+R FVA+ L +
Sbjct: 143 TALTQLVT---GFPKNRVMGQAGMLDTARFSHFVAEELGV 179
>UniRef50_Q838C9 Cluster: L-lactate dehydrogenase 2; n=9;
Bacilli|Rep: L-lactate dehydrogenase 2 - Enterococcus
faecalis (Streptococcus faecalis)
Length = 317
Score = 44.8 bits (101), Expect = 0.002
Identities = 39/170 (22%), Positives = 87/170 (51%), Gaps = 4/170 (2%)
Frame = +2
Query: 215 NVQVSVIGAASDIGSYVSLFLKRNSKVSKLHLYD-DDDRIKGTELELSNLP--GGPSVSA 385
N +V++IG +G+ ++ + ++L L D D + +G ++L + G +V+
Sbjct: 5 NKKVAIIGTGF-VGTSIAYSMINQGIANELILVDIDKAKSEGEAIDLLDGVSWGQENVNV 63
Query: 386 FIGDTNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAI 565
+ GD Q +++VV+ + +KPG +R ++ NA +++ + I + + I
Sbjct: 64 WAGDY---QDCQDADIVVITAGANQKPGQSRLDLVSINAEIMKTIVNNIMKSGFDGILVI 120
Query: 566 STNPINYLIPFASTVMYKYGCYNPSKMFGI-THIDTSRSRSFVAKALKIN 712
++NP++ L + V ++ S++ G T +DT+R R +++ L I+
Sbjct: 121 ASNPVDVL----TYVAWQASGLPVSRVIGTGTTLDTTRFRKELSQRLAID 166
>UniRef50_Q7MTK2 Cluster: Malate dehydrogenase; n=4;
Bacteroidales|Rep: Malate dehydrogenase - Porphyromonas
gingivalis (Bacteroides gingivalis)
Length = 334
Score = 44.0 bits (99), Expect = 0.004
Identities = 42/161 (26%), Positives = 73/161 (45%), Gaps = 2/161 (1%)
Frame = +2
Query: 221 QVSVIGAASDIGSYVSLFLKRNSKVSKLHLYDDDD-RIKGTELELSNLPGGPSVSAFIGD 397
+++++GAA IGS ++ L LYD ++G E+ + F D
Sbjct: 8 KLTIVGAAGMIGSNMAQTAAMMRLTPNLCLYDPFAVGLEGVAEEIRHCGFEGLNLTFTSD 67
Query: 398 TNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEA-FVAISTN 574
+++A+ + +V PRK G TRE +L NA + +L K I + + V I N
Sbjct: 68 --IKEALTDAKYIVSSGGAPRKEGMTREDLLKGNAEIAAQLGKDIKSYCPDCKHVIIIFN 125
Query: 575 PINYLIPFASTVMYKYGCYNPSKMFGITHIDTSRSRSFVAK 697
P + V Y PS++ + +D++R +S +AK
Sbjct: 126 PAD----ITGLVTLIYSGLKPSQVTTLAGLDSTRLQSELAK 162
>UniRef50_P0A3M9 Cluster: L-lactate dehydrogenase; n=140;
Bacteria|Rep: L-lactate dehydrogenase - Streptococcus
pneumoniae
Length = 328
Score = 43.6 bits (98), Expect = 0.005
Identities = 25/99 (25%), Positives = 54/99 (54%), Gaps = 1/99 (1%)
Frame = +2
Query: 425 SNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAISTNPINYLIPFAS 604
++LVV+ + P+KPG TR ++G N + + + + + ++ NP++ L S
Sbjct: 77 ADLVVITAGAPQKPGETRLDLVGKNLAINKSIVTQVVESGFKGIFLVAANPVDVLT--YS 134
Query: 605 TVMYKYGCYNPSKMFGI-THIDTSRSRSFVAKALKINAQ 718
T +K+ + ++ G T +D++R R +A+ L ++A+
Sbjct: 135 T--WKFSGFPKERVIGSGTSLDSARFRQALAEKLDVDAR 171
>UniRef50_P19869 Cluster: L-lactate dehydrogenase 2; n=17;
Bacteria|Rep: L-lactate dehydrogenase 2 -
Bifidobacterium longum
Length = 320
Score = 43.2 bits (97), Expect = 0.007
Identities = 37/169 (21%), Positives = 87/169 (51%), Gaps = 3/169 (1%)
Frame = +2
Query: 221 QVSVIGAASDIGSYVSLFLKRNSKVSKLHLYD-DDDRIKGTELELSNLPGG-PSVSAFIG 394
+++VIGA + +GS ++ + ++ L D +R++ L++ + P+VS I
Sbjct: 10 KLAVIGAGA-VGSTLAFAAAQRGIAREIVLEDIAKERVEAEVLDMQHGSSFYPTVS--ID 66
Query: 395 DTNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAISTN 574
++ + +++VV+ + +KPG +R +++GA +++ + + A + TN
Sbjct: 67 GSDDPEICRDADMVVITAGPRQKPGQSRLELVGATVNILKAIMPNLVKVAPNAIYMLITN 126
Query: 575 PINYLIPFASTVMYKYGCYNPSKMFGI-THIDTSRSRSFVAKALKINAQ 718
P++ A+ V K +++FG T++D++R R +A+ +N +
Sbjct: 127 PVD----IATHVAQKLTGLPENQIFGSGTNLDSARLRFLIAQQTGVNVK 171
>UniRef50_Q81K80 Cluster: L-lactate dehydrogenase 2; n=12;
Firmicutes|Rep: L-lactate dehydrogenase 2 - Bacillus
anthracis
Length = 314
Score = 43.2 bits (97), Expect = 0.007
Identities = 35/171 (20%), Positives = 80/171 (46%), Gaps = 3/171 (1%)
Frame = +2
Query: 209 KRNVQVSVIGAASDIGSYVSLFLKRNSKVSKLHLYD-DDDRIKGTELELSN-LPGGPSVS 382
K+ + V+ +G + + + L D ++ + +G ++LS+ +P PS +
Sbjct: 2 KKGINRVVLVGTGAVGCSYAYSMINQGVAEEFVLVDVNEAKAEGEAMDLSHAVPFSPSPT 61
Query: 383 AFIGDTNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVA 562
+ + ++LVV+ + +P+KPG TR ++ N + +++ + I +
Sbjct: 62 KVWSGSYAD--CKDADLVVITAGLPQKPGETRLDLVEKNTKIFKQIVRGIMDSGFDGIFL 119
Query: 563 ISTNPINYLIPFASTVMYKYGCYNPSKMFGI-THIDTSRSRSFVAKALKIN 712
I+TNP++ L + V +K ++ G T +D++R R + L ++
Sbjct: 120 IATNPVDIL----TYVTWKESGLPKERVIGSGTTLDSARFRYMLGDYLDVD 166
>UniRef50_A1HSK3 Cluster: Lactate/malate dehydrogenase; n=1;
Thermosinus carboxydivorans Nor1|Rep: Lactate/malate
dehydrogenase - Thermosinus carboxydivorans Nor1
Length = 303
Score = 42.7 bits (96), Expect = 0.009
Identities = 27/99 (27%), Positives = 52/99 (52%), Gaps = 1/99 (1%)
Frame = +2
Query: 425 SNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAISTNPINYLIPFAS 604
+++VV+ + +PRK R +L NA LI L + + + + TNP++ + A
Sbjct: 68 ADIVVITAGIPRKADEPRVLLLSRNAALIADLVRQAVHYSPNCIIFMVTNPLDVMTQLA- 126
Query: 605 TVMYKYGCYNPSKMFGI-THIDTSRSRSFVAKALKINAQ 718
Y+ +++ G+ T +DT+R RS++A A +A+
Sbjct: 127 ---YQVSGLPANRVIGMGTVLDTARYRSYLAVAFDADAR 162
>UniRef50_Q98PG4 Cluster: L-lactate dehydrogenase; n=1; Mycoplasma
pulmonis|Rep: L-lactate dehydrogenase - Mycoplasma
pulmonis
Length = 315
Score = 42.7 bits (96), Expect = 0.009
Identities = 25/92 (27%), Positives = 49/92 (53%), Gaps = 1/92 (1%)
Frame = +2
Query: 425 SNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAISTNPINYLIPFAS 604
++L+++ + P+K G TR +M+ N+ +++ + I F + +NP++ L +
Sbjct: 71 ADLLIVAAGRPQKQGETRLEMIADNSKIMKDIALEIKKSGFNGFTIVISNPVDIL----A 126
Query: 605 TVMYKYGCYNPSK-MFGITHIDTSRSRSFVAK 697
TV K + K M T +DTSR R F+++
Sbjct: 127 TVFQKVTNFPKEKVMSSGTFLDTSRFRKFLSE 158
>UniRef50_Q64YY6 Cluster: Malate dehydrogenase; n=5;
Bacteroidales|Rep: Malate dehydrogenase - Bacteroides
fragilis
Length = 333
Score = 41.1 bits (92), Expect = 0.027
Identities = 39/169 (23%), Positives = 74/169 (43%), Gaps = 2/169 (1%)
Frame = +2
Query: 215 NVQVSVIGAASDIGSYVSLFLKRNSKVSKLHLYDD-DDRIKGTELELSNLPGGPSVSAFI 391
N +++++GAA IGS ++ + LYD ++G EL + +
Sbjct: 6 NEKLTIVGAAGMIGSNMAQTALMMKLTPNICLYDPYAPALEGVAEELYHCAFEGVNLTYT 65
Query: 392 GDTNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEA-FVAIS 568
D +++A+ + +V RK G TRE +L NA + + K I + V +
Sbjct: 66 SD--IKEALSGAKYIVSSGGAARKAGMTREDLLKGNAEIAAQFGKDIRQYCPDVKHVVVV 123
Query: 569 TNPINYLIPFASTVMYKYGCYNPSKMFGITHIDTSRSRSFVAKALKINA 715
NP + ++ Y PS++ + +D++R ++ + K L I A
Sbjct: 124 FNPAD----ITGLIVLLYAGLKPSQVSTLAALDSTRLQNELVKYLHIPA 168
>UniRef50_P50933 Cluster: L-lactate dehydrogenase; n=7;
Bacteria|Rep: L-lactate dehydrogenase - Deinococcus
radiodurans
Length = 304
Score = 41.1 bits (92), Expect = 0.027
Identities = 30/131 (22%), Positives = 62/131 (47%), Gaps = 2/131 (1%)
Frame = +2
Query: 218 VQVSVIGAASDIGSYVSLFLKRNSKVSKLHLYD-DDDRIKGTELELSNL-PGGPSVSAFI 391
++V V+G +GS + L S+L L D D+DR + ++++ P +
Sbjct: 1 MKVGVVGTGF-VGSTAAFALVLRGSCSELVLVDRDEDRAQAEAEDIAHAAPVSHGTRVWH 59
Query: 392 GDTNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAIST 571
G + + +V++ + +KPG +R +L NA + + L I +A + +++
Sbjct: 60 GG---HSELADAQVVILTAGANQKPGESRLDLLEKNADIFRELVPQITRAAPDAVLLVTS 116
Query: 572 NPINYLIPFAS 604
NP++ L A+
Sbjct: 117 NPVDLLTDLAT 127
>UniRef50_A2G340 Cluster: Malate dehydrogenase; n=18;
Trichomonadinae|Rep: Malate dehydrogenase - Trichomonas
vaginalis G3
Length = 339
Score = 40.7 bits (91), Expect = 0.035
Identities = 36/171 (21%), Positives = 75/171 (43%), Gaps = 8/171 (4%)
Frame = +2
Query: 221 QVSVIGAASDIGSYVSLFLKRNSKVSK----LHLYD---DDDRIKGTELELSNLPGGPSV 379
+V + GAA IG +S ++ + LHL+D +R+ +EL + P +
Sbjct: 6 RVLITGAAGQIGYVLSHWIASGELYGERPVILHLFDIPVAQNRLTALTMELQDC-AFPHL 64
Query: 380 SAFIGDTNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAF- 556
+ ++ T EQA + +V+ +P K G R ++G+N+ + + + ++ +
Sbjct: 65 AGYVATTEPEQAFKDIDCAFLVASVPMKSGQIRSDLIGSNSIIFKNTGEWLSQYAKPTVK 124
Query: 557 VAISTNPINYLIPFASTVMYKYGCYNPSKMFGITHIDTSRSRSFVAKALKI 709
V + NP N A + P ++ +D +R+ +A+ L +
Sbjct: 125 VLVIGNPDN---TNAEIALLHAKNLKPENFSSLSLLDQNRAYHAIAEKLGV 172
>UniRef50_Q4J9W2 Cluster: Putative uncharacterized protein; n=1;
Sulfolobus acidocaldarius|Rep: Putative uncharacterized
protein - Sulfolobus acidocaldarius
Length = 193
Score = 40.7 bits (91), Expect = 0.035
Identities = 25/80 (31%), Positives = 40/80 (50%), Gaps = 3/80 (3%)
Frame = +2
Query: 149 QKIFCCLFATQLKKNTLILQKRNVQVSVIGAASDIGS---YVSLFLKRNSKVSKLHLYDD 319
+ ++ L + K N+L L RN+++ I DIG YV +F+ K + +H+ +
Sbjct: 88 EPVYANLLFRKSKVNSLTLVLRNMKILKISYPHDIGDSLFYVKVFIDYADKFNTVHINSE 147
Query: 320 DDRIKGTELELSNLPGGPSV 379
+D I L NLPG SV
Sbjct: 148 NDAIIFLNLARDNLPGKVSV 167
>UniRef50_P20619 Cluster: L-lactate dehydrogenase X; n=14;
Bacillales|Rep: L-lactate dehydrogenase X - Bacillus
psychrosaccharolyticus
Length = 319
Score = 40.7 bits (91), Expect = 0.035
Identities = 39/173 (22%), Positives = 87/173 (50%), Gaps = 6/173 (3%)
Frame = +2
Query: 209 KRNV-QVSVIGAASDIGSYVSLFLKRNSKVSKLHLYD-DDDRIKGTELELSN---LPGGP 373
+RN+ +V++IGA S +GS + L S +L + D ++D+ G ++L++ P
Sbjct: 3 QRNINRVALIGAGS-VGSSYAFALLNQSITEELVIIDVNEDKAMGDAMDLNHGKIFAPNP 61
Query: 374 SVSAFIGDTNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEA 553
+ + + + ++A ++V + + +KPG TR ++ N + + L + A +
Sbjct: 62 TKTWYGNYDDCKEA----DIVCICAGANQKPGETRLDLVEKNLKIFKSLVDQVMASGFDG 117
Query: 554 FVAISTNPINYLIPFASTVMYKYGCYNPSKMFGI-THIDTSRSRSFVAKALKI 709
I+TNP++ ++ +A+ +K+ ++ G T +D+ R R + + I
Sbjct: 118 IFLIATNPVD-ILTYAT---WKFSGLPKERVIGSGTILDSGRFRFLLGEYFDI 166
>UniRef50_UPI00015BB1FC Cluster: malate dehydrogenase (NAD); n=1;
Ignicoccus hospitalis KIN4/I|Rep: malate dehydrogenase
(NAD) - Ignicoccus hospitalis KIN4/I
Length = 311
Score = 40.3 bits (90), Expect = 0.047
Identities = 26/97 (26%), Positives = 49/97 (50%), Gaps = 1/97 (1%)
Frame = +2
Query: 416 IHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAISTNPINYLIP 595
+ +++ +V+ + PRK +R + NA +I+ + + +N AF + TNP++ +
Sbjct: 72 VENADAIVITAGKPRKADMSRRDLAKVNAQIIRDIGDKLRDRNPGAFYMVITNPVDVMTM 131
Query: 596 FASTVMYKYGCYNPSKMFGI-THIDTSRSRSFVAKAL 703
S V+ N + G T +DT R RS V++ L
Sbjct: 132 ILSDVI-----GNKGTVIGTGTSLDTYRFRSAVSELL 163
>UniRef50_A2SNY0 Cluster: Malate/lactate dehydrogenases-like
protein; n=1; Methylibium petroleiphilum PM1|Rep:
Malate/lactate dehydrogenases-like protein - Methylibium
petroleiphilum (strain PM1)
Length = 432
Score = 39.9 bits (89), Expect = 0.062
Identities = 28/129 (21%), Positives = 61/129 (47%), Gaps = 1/129 (0%)
Frame = +2
Query: 221 QVSVIGAASDIGSYVSLFLKRNSKVSKLHLYDDDDRIK-GTELELSNLPGGPSVSAFIGD 397
+ V+GA +G+ +L L + S++ L D + G L++ + G S +
Sbjct: 125 KAGVVGAGH-VGAMTALRLAESDLFSEVALVDVVPGLAAGLALDMWHGAGLYGFSTRLSG 183
Query: 398 TNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAISTNP 577
++ A+ + +V+ + PR+PG +R + NA ++ +C+ I + + I +NP
Sbjct: 184 SDDLVALAGAEYIVITAGKPRQPGMSRTDLTVVNAEIMTSVCRGIRTHAPNSTLVIVSNP 243
Query: 578 INYLIPFAS 604
+ + A+
Sbjct: 244 LEEMTHLAA 252
>UniRef50_Q9GSY3 Cluster: Malate dehydrogenase; n=1; Hypotrichomonas
acosta|Rep: Malate dehydrogenase - Hypotrichomonas
acosta
Length = 318
Score = 39.5 bits (88), Expect = 0.082
Identities = 34/127 (26%), Positives = 57/127 (44%), Gaps = 1/127 (0%)
Frame = +2
Query: 332 KGTELELSNLPGGPSVSAFIGDTNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLI 511
+G LEL + + D LE+A ++ +V+ +P KPG R +L N P+
Sbjct: 31 EGLALELEDCAFQNLEKTIVTD-KLEEACKDIDIAFLVASVPLKPGEHRVNLLTKNTPIF 89
Query: 512 QRLCKAIAAQNQEAFVAIST-NPINYLIPFASTVMYKYGCYNPSKMFGITHIDTSRSRSF 688
+ + +A++ + A+ NP+N A K N S M + H +RS S
Sbjct: 90 KAIGEALSEYAKPTVRALVVGNPVNSNCLVAMLNAPKLSAENFSCMCTLDH---NRSVSR 146
Query: 689 VAKALKI 709
+A LK+
Sbjct: 147 IASHLKV 153
>UniRef50_Q4A0K7 Cluster: Lactate dehydrogenase; n=1; Staphylococcus
saprophyticus subsp. saprophyticus ATCC 15305|Rep:
Lactate dehydrogenase - Staphylococcus saprophyticus
subsp. saprophyticus (strain ATCC 15305 /DSM 20229)
Length = 310
Score = 39.1 bits (87), Expect = 0.11
Identities = 38/167 (22%), Positives = 80/167 (47%), Gaps = 3/167 (1%)
Frame = +2
Query: 221 QVSVIGAASDIGSYVSLFLKRNSKVSKLHLYDDD-DRIKGTELELSNLPGGPSVSAFIGD 397
++ +IG +G+ V +++ + S++ L DD D G L+ + G + +
Sbjct: 3 KLGIIGLGK-VGTQVLTDVQQLNLFSEIILIDDRADVASGEALDHIHSQGLINTAHIKIR 61
Query: 398 TNLEQAIHSSNLVVMV-SRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAISTN 574
+ + Q + ++ +V+ S K R + N +I+ + IA QEA V + +N
Sbjct: 62 SGVYQDLTDADFIVIAASEATDKNNGDRTLLAQGNHDIIKGIMSQIAEVTQEAVVILISN 121
Query: 575 PINYLIPFASTVMYKYGCYNPSKMFGI-THIDTSRSRSFVAKALKIN 712
P++ ++ FA+ + Y K+ G T ++TSR ++ +A +I+
Sbjct: 122 PVDSMVYFANQIDYP-----AHKIIGTGTALETSRFKTIIADHYQID 163
>UniRef50_Q23CW4 Cluster: Malate dehydrogenase, cytoplasmic,
putative; n=3; Oligohymenophorea|Rep: Malate
dehydrogenase, cytoplasmic, putative - Tetrahymena
thermophila SB210
Length = 365
Score = 39.1 bits (87), Expect = 0.11
Identities = 37/143 (25%), Positives = 61/143 (42%), Gaps = 10/143 (6%)
Frame = +2
Query: 185 KKNTLILQKRN--VQVSVIGAASDIG-SYVSLFLKRN---SKVSKLHLYD---DDDRIKG 337
K T + K N + V V GAA IG +++ L L K L L D + ++G
Sbjct: 33 KSKTTVYSKENDEINVCVTGAAGQIGYAFLPLLLTGQCFGDKKINLRLLDVPQAESILQG 92
Query: 338 TELELSNLPGGPSVSAFIGDTNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQR 517
ELEL + P + + +N ++ V + PRKPG R+ +L N + ++
Sbjct: 93 VELELQD-GAYPLLKSIKTGSNESILFQDVDVAVFIGGFPRKPGMERKDLLTINGNIFKK 151
Query: 518 LCKAI-AAQNQEAFVAISTNPIN 583
+A+ + + NP N
Sbjct: 152 QGQALDTVAKKTCKSLVVANPAN 174
>UniRef50_Q1FID3 Cluster: L-lactate dehydrogenase precursor; n=1;
Clostridium phytofermentans ISDg|Rep: L-lactate
dehydrogenase precursor - Clostridium phytofermentans
ISDg
Length = 325
Score = 38.7 bits (86), Expect = 0.14
Identities = 21/97 (21%), Positives = 48/97 (49%), Gaps = 1/97 (1%)
Frame = +2
Query: 425 SNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAISTNPINYLIPFAS 604
+++VV+ + P KPG +R LG +A ++ + + + + TNP++ + +
Sbjct: 76 ADIVVITAGPPPKPGQSRLDTLGLSADIVSTIVEPVMKSGFNGIFLVVTNPVDSIAQY-- 133
Query: 605 TVMYKYGCYNPSKMFGI-THIDTSRSRSFVAKALKIN 712
+Y+ ++ G T ID++R + F+ L ++
Sbjct: 134 --VYQLSGLPKQQVLGTGTAIDSARLKHFIGDILHVD 168
>UniRef50_Q81XJ7 Cluster: L-lactate dehydrogenase 3; n=13;
Firmicutes|Rep: L-lactate dehydrogenase 3 - Bacillus
anthracis
Length = 316
Score = 38.7 bits (86), Expect = 0.14
Identities = 31/172 (18%), Positives = 83/172 (48%), Gaps = 2/172 (1%)
Frame = +2
Query: 203 LQKRNVQVSVIGAASDIGSYVSLFLKRNSKVSKLHLYD-DDDRIKGTELELSNLPGGPSV 379
+++ ++++IG +GS + + +L L D + +R G ++LS+ +
Sbjct: 1 MKRHTRKIAIIGTGL-VGSSCAYSIVNQGICEELLLIDINHERAVGEAMDLSHCINFTNT 59
Query: 380 SAFIGDTNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFV 559
+ + E ++V++ + KPG +R LGA+A +++ + + +
Sbjct: 60 RTKVYAGSYEDC-KDMDIVIITAGPAPKPGQSRLDTLGASAKIMESVVGGVMESGFDGIF 118
Query: 560 AISTNPINYLIPFASTVMYKYGCYNPSKMFGI-THIDTSRSRSFVAKALKIN 712
+++NP++ + + ++K +++ G T +D+SR R+ +++ L ++
Sbjct: 119 LLASNPVDII----TYQVWKLSGLPRNRVIGTGTSLDSSRLRTILSEMLHVD 166
>UniRef50_Q8IE66 Cluster: Oxidoreductase, putative; n=6;
Plasmodium|Rep: Oxidoreductase, putative - Plasmodium
falciparum (isolate 3D7)
Length = 334
Score = 37.9 bits (84), Expect = 0.25
Identities = 40/175 (22%), Positives = 86/175 (49%), Gaps = 8/175 (4%)
Frame = +2
Query: 212 RNVQVSVIGAASDIGSYVS-LFLKRNSKVSKLHLYDDDDRIKGTELE-LSNLPGGPSVSA 385
++ ++SV+GA DIG ++ + ++N LH + D KG L+ L P S
Sbjct: 5 KHPKISVLGAG-DIGCALAHMICEKNLGDVVLHDFRKD-LPKGRALDILHTRPLNRSRIN 62
Query: 386 FIGDTNLEQAIHSSNLVVMVSRMPRK-----PGNTREQMLGANAPLIQRLCKAIAAQNQE 550
+G + S +VV + R+ + +Q+ +N L++ + K++ +
Sbjct: 63 ILGTNEITDIKDSLVVVVTIEVSEREFAEFDEEDLEKQVYTSNVKLLKEVAKSLKKHCPQ 122
Query: 551 AFVAISTNPINYLIPFASTVMYKYGCYNPSKMFGITHI-DTSRSRSFVAKALKIN 712
AFV ++T+P++ + + V+ ++ P K+ G+ + ++R R +A+ L++N
Sbjct: 123 AFVVVTTSPVDCM----AKVLQEHANIPPHKICGMAGVLHSARLRHNLAEKLRVN 173
>UniRef50_A3DCA4 Cluster: L-lactate dehydrogenase precursor; n=2;
Clostridium|Rep: L-lactate dehydrogenase precursor -
Clostridium thermocellum (strain ATCC 27405 / DSM 1237)
Length = 318
Score = 37.5 bits (83), Expect = 0.33
Identities = 34/173 (19%), Positives = 83/173 (47%), Gaps = 3/173 (1%)
Frame = +2
Query: 209 KRNVQVSVIGAASDIGSYVSLFLKRNSKVSKLHLYDD-DDRIKGTELELSN-LPGGPSVS 382
K +V++IGA +G+ + + ++L L D ++ G +++++ LP +S
Sbjct: 5 KSRSKVAIIGAGF-VGASAAFTMALRQTANELVLIDVFKEKAIGEAMDINHGLPFMGQMS 63
Query: 383 AFIGDTNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVA 562
+ GD + + +++V+ + RKPG TR + N + + + + I +
Sbjct: 64 LYAGDYS---DVKDCDVIVVTAGANRKPGETRLDLAKKNVMIAKEVTQNIMKYYNHGVIL 120
Query: 563 ISTNPINYLIPFASTVMYKYGCYNPSKMFGI-THIDTSRSRSFVAKALKINAQ 718
+ +NP++ + + ++ K+ K+ G T +D+ R R +++ L ++ +
Sbjct: 121 VVSNPVDII----TYMIQKWSGLPVGKVIGSGTVLDSIRFRYLLSEKLGVDVK 169
>UniRef50_P62051 Cluster: L-lactate dehydrogenase; n=2;
Desulfovibrio vulgaris subsp. vulgaris|Rep: L-lactate
dehydrogenase - Desulfovibrio vulgaris (strain
Hildenborough / ATCC 29579 / NCIMB8303)
Length = 309
Score = 37.5 bits (83), Expect = 0.33
Identities = 24/99 (24%), Positives = 50/99 (50%), Gaps = 1/99 (1%)
Frame = +2
Query: 425 SNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAISTNPINYLIPFAS 604
+ +VV+ + + PG +R ++ NA + + + A+ + ++TNP++ L A
Sbjct: 69 ARIVVVTAGAKQMPGQSRLDLVRVNAGITRDILTAVMQYADDPLYIMATNPVDVLTHVAR 128
Query: 605 TVMYKYGCYNPSKMFGI-THIDTSRSRSFVAKALKINAQ 718
TV P ++ G T +D++R R VA+ L ++ +
Sbjct: 129 TVT----GVAPGRVIGSGTVLDSARFRGHVAEILGVDVR 163
>UniRef50_Q6A6E3 Cluster: L-lactate dehydrogenase; n=1;
Propionibacterium acnes|Rep: L-lactate dehydrogenase -
Propionibacterium acnes
Length = 321
Score = 37.1 bits (82), Expect = 0.44
Identities = 23/87 (26%), Positives = 43/87 (49%), Gaps = 4/87 (4%)
Frame = +2
Query: 359 LPGGPSVSAFIGD----TNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCK 526
LP +V+ + GD +N + I ++ + S P G R ++ N +I+
Sbjct: 56 LPNVTNVAVYAGDYDDLSNADVIIMTAGPSIDASNGPAT-GAARRELAATNGKIIRSTMT 114
Query: 527 AIAAQNQEAFVAISTNPINYLIPFAST 607
I ++N +A + I +NP++ L+ AST
Sbjct: 115 QITSRNHDAAIIICSNPLDALVHIAST 141
>UniRef50_Q9KGT7 Cluster: Restriction endonuclease Hpy8I; n=5;
Helicobacter|Rep: Restriction endonuclease Hpy8I -
Helicobacter pylori (Campylobacter pylori)
Length = 207
Score = 37.1 bits (82), Expect = 0.44
Identities = 16/54 (29%), Positives = 27/54 (50%), Gaps = 2/54 (3%)
Frame = -3
Query: 288 EFRFRKRDTYEPISLAAPITDTCTFLFCKISVFFFSC--VANKQQNIFWAIFFQ 133
+F F+K D + P+++ T T L CK+ +++ C V I W +FQ
Sbjct: 58 DFSFKKNDIFYPVNIKTTTTKTADNLNCKLGIYYALCGLVPEFNNEIAWEKYFQ 111
>UniRef50_P0C0J4 Cluster: L-lactate dehydrogenase; n=5; Mycoplasma
hyopneumoniae|Rep: L-lactate dehydrogenase - Mycoplasma
hyopneumoniae
Length = 315
Score = 37.1 bits (82), Expect = 0.44
Identities = 23/101 (22%), Positives = 50/101 (49%), Gaps = 2/101 (1%)
Frame = +2
Query: 416 IHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAISTNPINYLIP 595
+ ++ +V+ + P+KPG TR +++ N +I+ + + I NP++ +
Sbjct: 69 LKDADFIVITAGRPQKPGETRLELVADNIRIIREIALKVKESGFSGISIIVANPVDII-- 126
Query: 596 FASTVMYKYGC-YNPSKMFGI-THIDTSRSRSFVAKALKIN 712
T Y+ ++ K+ G T +DT+R + +AK K++
Sbjct: 127 ---TRAYRDASGFSDQKVIGSGTVLDTARLQFAIAKRAKVS 164
>UniRef50_Q9EVR0 Cluster: L-lactate dehydrogenase; n=1; Selenomonas
ruminantium|Rep: L-lactate dehydrogenase - Selenomonas
ruminantium
Length = 318
Score = 36.7 bits (81), Expect = 0.58
Identities = 32/135 (23%), Positives = 67/135 (49%), Gaps = 6/135 (4%)
Frame = +2
Query: 221 QVSVIGAASDIGSYVSLFLKRNSKVSKLHLYD-DDDRIKGTELELSNLPG---GPSVSAF 388
++ VIGA S++GS V+ + +++ L D ++D+ G + S+ ++
Sbjct: 6 KIVVIGA-SNVGSAVANKIADFQLATEVVLIDLNEDKAWGEAKDSSHATSCIYSTNIKFH 64
Query: 389 IGDTNLEQAIHSSNLVVMVSRMPRKPGNT--REQMLGANAPLIQRLCKAIAAQNQEAFVA 562
+GD + +N++V+ + +PG T R ++ G NA ++ + I + +EA +
Sbjct: 65 LGDY---EDCKDANIIVITAGPSIRPGETPDRLKLAGTNAKIMSSVMGEIVKRTKEAMII 121
Query: 563 ISTNPINYLIPFAST 607
+ TNP++ ST
Sbjct: 122 MITNPLDVATYVVST 136
>UniRef50_Q4CTT8 Cluster: Putative uncharacterized protein; n=1;
Trypanosoma cruzi|Rep: Putative uncharacterized protein
- Trypanosoma cruzi
Length = 211
Score = 35.5 bits (78), Expect = 1.3
Identities = 15/44 (34%), Positives = 26/44 (59%), Gaps = 1/44 (2%)
Frame = -3
Query: 153 FWAIFFQ-YFCKICFLTSHFTIFVTFLLRGHDICCRY*LVLSSL 25
F+ +F +FC +C L F++F F LR ++I C + +SS+
Sbjct: 34 FFLLFISHFFCAVCLLFPFFSLFFFFFLRAYNIRCTHTKAMSSV 77
>UniRef50_A5Z9B1 Cluster: Putative uncharacterized protein; n=1;
Eubacterium ventriosum ATCC 27560|Rep: Putative
uncharacterized protein - Eubacterium ventriosum ATCC
27560
Length = 312
Score = 35.1 bits (77), Expect = 1.8
Identities = 35/170 (20%), Positives = 75/170 (44%), Gaps = 2/170 (1%)
Frame = +2
Query: 215 NVQVSVIGAASDIGSYVSLFLKRNSKVSKLHLYDDD-DRIKGTELELSNLPGGPSVSAFI 391
N ++ +IGA +GS+ + L ++ L D D + K +++++ + S +
Sbjct: 4 NRKIVIIGAGH-VGSHCAYALAIQGICDEIVLVDKDRTKAKSHSMDIADSVSFFNSSVIV 62
Query: 392 GDTNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAIST 571
+ ++++V+ + +PR PG TR +L + ++ + + + + T
Sbjct: 63 RCGDYSDC-KDADIIVISAGVPRLPGQTRLDVLDGSVECVRDIVSNLNKIEIKGIIITIT 121
Query: 572 NPINYLIPFASTVMYKYGCYNPSKMFGI-THIDTSRSRSFVAKALKINAQ 718
NP + + F + K +++F T +DT+R R VA I Q
Sbjct: 122 NPADIIADF----VRKATGLPKNRVFSTGTSLDTARMRRTVADLCNIAPQ 167
>UniRef50_A5IYS9 Cluster: L-lactate dehydrogenase; n=2;
Mycoplasma|Rep: L-lactate dehydrogenase - Mycoplasma
agalactiae
Length = 323
Score = 35.1 bits (77), Expect = 1.8
Identities = 33/142 (23%), Positives = 64/142 (45%)
Frame = +2
Query: 269 LFLKRNSKVSKLHLYDDDDRIKGTELELSNLPGGPSVSAFIGDTNLEQAIHSSNLVVMVS 448
+ + +N ++++ H +D +D + S +P S F T LE + + +V+ S
Sbjct: 30 VLVDKNVQIAEAHAHDFEDMV-------SLMPRNGST--FRPGTLLEDSKDADVVVITAS 80
Query: 449 RMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAISTNPINYLIPFASTVMYKYGC 628
K + R + GANA L+Q K + A + V ++ NP + + A+ V Y
Sbjct: 81 IPADKTFSDRMALAGANAKLMQSFAKDLDAAGFKGIVVVAANPCDVM---AAAVHYGSKI 137
Query: 629 YNPSKMFGITHIDTSRSRSFVA 694
+ T+++T R + +A
Sbjct: 138 PANRVISAGTNLETGRLKKMLA 159
>UniRef50_Q4UJ29 Cluster: L-lactate dehydrogenase, putative; n=2;
Theileria|Rep: L-lactate dehydrogenase, putative -
Theileria annulata
Length = 367
Score = 35.1 bits (77), Expect = 1.8
Identities = 21/80 (26%), Positives = 45/80 (56%), Gaps = 1/80 (1%)
Frame = +2
Query: 476 REQMLGANAPLIQRLCKAIAAQNQEAFVAISTNPINYLIPFASTVMYKYGCYNPSKMFGI 655
R+ ++G N+ +I+ + + I EAFV + TNP++ ++ +M K + + + G+
Sbjct: 143 RDDLVGYNSKIIRDVGENIKKYAPEAFVIVITNPMDVMV----HLMLKVTGFPKNMVVGM 198
Query: 656 TH-IDTSRSRSFVAKALKIN 712
+D+SR ++A+ L +N
Sbjct: 199 GGLLDSSRMNCYIAEKLGVN 218
>UniRef50_Q22N17 Cluster: Putative uncharacterized protein; n=1;
Tetrahymena thermophila SB210|Rep: Putative
uncharacterized protein - Tetrahymena thermophila SB210
Length = 3435
Score = 35.1 bits (77), Expect = 1.8
Identities = 15/53 (28%), Positives = 31/53 (58%)
Frame = +2
Query: 317 DDDRIKGTELELSNLPGGPSVSAFIGDTNLEQAIHSSNLVVMVSRMPRKPGNT 475
+ + I+G +E +L G P + F+G N+ + S N ++++S+ P+K N+
Sbjct: 1400 NQEAIQGASIEAKSLKGSPLCTRFVG-KNILATVDSQNNLILMSQQPQKNQNS 1451
>UniRef50_Q9GPV2 Cluster: Cytosolic malate dehydrogenase; n=4;
Trichomonadida|Rep: Cytosolic malate dehydrogenase -
Tetratrichomonas gallinarum
Length = 314
Score = 34.3 bits (75), Expect = 3.1
Identities = 21/86 (24%), Positives = 40/86 (46%), Gaps = 1/86 (1%)
Frame = +2
Query: 329 IKGTELELSNLPGGPSVSAFIGDTNLEQAIHSSNLVVMVSRMPRKPGNTREQMLGANAPL 508
++G +EL + P+V+ + +E+A ++ +V PRK G R +L N +
Sbjct: 31 LEGCVMELQDC-AFPNVAGIVWTDKIEEAFKDVDVAFLVGSFPRKDGMDRSDLLAKNGGI 89
Query: 509 IQRLCKAIA-AQNQEAFVAISTNPIN 583
KA++ ++ V + NP N
Sbjct: 90 FTVQGKALSDFAKKDVKVLVVGNPAN 115
>UniRef50_A3JXA9 Cluster: L-lactate dehydrogenase; n=1; Sagittula
stellata E-37|Rep: L-lactate dehydrogenase - Sagittula
stellata E-37
Length = 300
Score = 33.9 bits (74), Expect = 4.1
Identities = 21/99 (21%), Positives = 50/99 (50%), Gaps = 1/99 (1%)
Frame = +2
Query: 416 IHSSNLVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAISTNPINYLIP 595
+ +++V++ + +KPG +R ++L NA + + + + +A + I++NP++ +
Sbjct: 56 LSGADVVILACGVSQKPGESRLELLSRNAEVFRAVVGDVTRAAPDAILLIASNPVDIM-- 113
Query: 596 FASTVMYKYGCYNPSKMFGI-THIDTSRSRSFVAKALKI 709
+ V ++ G T +DT+R R + + L I
Sbjct: 114 --THVTQALSGLPAGRVIGSGTILDTARFRWLLGRHLNI 150
>UniRef50_A1ZW20 Cluster: Putative uncharacterized protein; n=1;
Microscilla marina ATCC 23134|Rep: Putative
uncharacterized protein - Microscilla marina ATCC 23134
Length = 291
Score = 33.9 bits (74), Expect = 4.1
Identities = 22/68 (32%), Positives = 36/68 (52%)
Frame = +2
Query: 263 VSLFLKRNSKVSKLHLYDDDDRIKGTELELSNLPGGPSVSAFIGDTNLEQAIHSSNLVVM 442
+S + K V+K +++ +D R G +L+ NLPG AF N E + +LV +
Sbjct: 185 ISPYSKIKMSVTKQYIHWNDARSTG-QLKKMNLPGTVVGGAFFS-ANYELGTVAYHLVAL 242
Query: 443 VSRMPRKP 466
+R P+KP
Sbjct: 243 YTRQPQKP 250
>UniRef50_Q27743 Cluster: L-lactate dehydrogenase; n=17;
Apicomplexa|Rep: L-lactate dehydrogenase - Plasmodium
falciparum (isolate CDC / Honduras)
Length = 316
Score = 33.5 bits (73), Expect = 5.4
Identities = 29/170 (17%), Positives = 82/170 (48%), Gaps = 7/170 (4%)
Frame = +2
Query: 221 QVSVIGAASDIGSYVSLFLKRNSKVSKLHLYDDDDRIK-GTELELSNLPGGPSVSAFIGD 397
++ ++G+ G +L +++N + + L+D + G L+ S+ + +
Sbjct: 6 KIVLVGSGMIGGVMATLIVQKN--LGDVVLFDIVKNMPHGKALDTSHTNVMAYSNCKVSG 63
Query: 398 TNLEQAIHSSNLVVMVSRMPRKPGNT-----REQMLGANAPLIQRLCKAIAAQNQEAFVA 562
+N + +++V++ + + PG + R+ +L N ++ + I AF+
Sbjct: 64 SNTYDDLAGADVVIVTAGFTKAPGKSDKEWNRDDLLPLNNKIMIEIGGHIKKNCPNAFII 123
Query: 563 ISTNPINYLIPFASTVMYKYGCYNPSKMFGITHI-DTSRSRSFVAKALKI 709
+ TNP++ ++ +++++ +K+ G+ + DTSR + ++++ L +
Sbjct: 124 VVTNPVDVMV----QLLHQHSGVPKNKIIGLGGVLDTSRLKYYISQKLNV 169
>UniRef50_Q8EYA2 Cluster: Putative uncharacterized protein; n=4;
Leptospira|Rep: Putative uncharacterized protein -
Leptospira interrogans
Length = 365
Score = 32.7 bits (71), Expect = 9.4
Identities = 21/67 (31%), Positives = 32/67 (47%), Gaps = 1/67 (1%)
Frame = -3
Query: 264 TYEPISLAA-PITDTCTFLFCKISVFFFSCVANKQQNIFWAIFFQYFCKICFLTSHFTIF 88
TY+ I + P + F+FC IS+FF +N+ IF ++ + FL S T+F
Sbjct: 96 TYDTIQIFLNPFAEITVFIFCIISLFFTDFYSNRSGVIFIVVYCSIGFILRFLES--TVF 153
Query: 87 VTFLLRG 67
L G
Sbjct: 154 YRISLLG 160
>UniRef50_Q4JY42 Cluster: L-lactate dehydrogenase; n=1;
Corynebacterium jeikeium K411|Rep: L-lactate
dehydrogenase - Corynebacterium jeikeium (strain K411)
Length = 326
Score = 32.7 bits (71), Expect = 9.4
Identities = 19/85 (22%), Positives = 42/85 (49%), Gaps = 1/85 (1%)
Frame = +2
Query: 431 LVVMVSRMPRKPGNTREQMLGANAPLIQRLCKAIAAQNQEAFVAISTNPINYLIPFASTV 610
+V + + +KPG TR ++ N + + + + + +++NP++ L S
Sbjct: 86 MVCICAGAAQKPGETRLDLVAKNTAIFKTIVGDVMSHGFNGIFLVASNPVDIL----SYA 141
Query: 611 MYKYGCYNPSKMFGI-THIDTSRSR 682
+K+ + S++ G T +DT+R R
Sbjct: 142 TWKFSGMDSSRVIGSGTILDTARFR 166
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 682,209,487
Number of Sequences: 1657284
Number of extensions: 13602501
Number of successful extensions: 34309
Number of sequences better than 10.0: 118
Number of HSP's better than 10.0 without gapping: 33015
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 34267
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 58264468239
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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