Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmte4b12
(734 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
CR456587-1|CAG30473.1| 358|Homo sapiens STK22A protein. 135 1e-31
BC037781-1|AAH37781.1| 358|Homo sapiens testis-specific serine ... 135 1e-31
AF362953-1|AAK98531.1| 358|Homo sapiens testis specific serine/... 135 1e-31
AB284523-1|BAF41974.1| 358|Homo sapiens testis-specific serine ... 135 1e-31
BC022515-1|AAH22515.1| 367|Homo sapiens testis-specific serine ... 135 2e-31
AY028964-1|AAK27734.1| 367|Homo sapiens testis-specific serine/... 135 2e-31
AB284522-1|BAF41973.1| 367|Homo sapiens testis-specific serine ... 135 2e-31
AY461663-1|AAS17971.1| 328|Homo sapiens testis-specific serine ... 128 2e-29
BC035354-1|AAH35354.1| 268|Homo sapiens testis-specific serine ... 120 5e-27
AY048701-1|AAL02128.1| 268|Homo sapiens TSSK3 protein. 120 5e-27
AL109945-4|CAI22888.1| 268|Homo sapiens testis-specific serine ... 120 5e-27
AF296450-1|AAK97141.1| 268|Homo sapiens testis-specific serine/... 120 5e-27
BC014611-1|AAH14611.1| 273|Homo sapiens testis-specific serine ... 117 4e-26
AK172841-1|BAD18805.1| 406|Homo sapiens protein ( Homo sapiens ... 117 4e-26
AF329483-1|AAK48827.1| 273|Homo sapiens serine/threonine protei... 117 4e-26
AK131042-1|BAC85482.1| 338|Homo sapiens protein ( Homo sapiens ... 117 5e-26
BC084540-1|AAH84540.1| 724|Homo sapiens MAP/microtubule affinit... 105 1e-22
BC008771-1|AAH08771.2| 778|Homo sapiens MARK2 protein protein. 105 1e-22
AB188493-1|BAD37141.1| 719|Homo sapiens serine/threonine kinase... 105 1e-22
BC038504-1|AAH38504.1| 783|Homo sapiens SNF1-like kinase protein. 104 4e-22
AP001751-1|BAA95536.1| 786|Homo sapiens SNF1LK protein. 104 4e-22
AK131076-1|BAC85126.1| 764|Homo sapiens FLJ00263 protein protein. 104 4e-22
AB047786-1|BAD74070.1| 783|Homo sapiens serine/threonine protei... 104 4e-22
X97630-1|CAA66229.1| 745|Homo sapiens serine/threonine protein ... 103 9e-22
BT007342-1|AAP36006.1| 755|Homo sapiens MAP/microtubule affinit... 103 9e-22
AF387638-1|AAK82368.1| 691|Homo sapiens Ser/Thr protein kinase ... 103 9e-22
BC117183-1|AAI17184.1| 926|Homo sapiens SNF1-like kinase 2 prot... 101 2e-21
BC113459-1|AAI13460.1| 926|Homo sapiens SNF1-like kinase 2 prot... 101 2e-21
AB084424-1|BAB91442.1| 346|Homo sapiens KIAA0781 protein protein. 101 2e-21
AB018324-1|BAA34501.3| 950|Homo sapiens KIAA0781 protein protein. 101 2e-21
U64205-1|AAC15093.1| 729|Homo sapiens Cdc25C associated protein... 101 3e-21
BC024773-1|AAH24773.1| 729|Homo sapiens MAP/microtubule affinit... 101 3e-21
AF387637-1|AAK82367.1| 744|Homo sapiens Ser/Thr protein kinase ... 101 3e-21
BC114478-1|AAI14479.1| 795|Homo sapiens MARK1 protein protein. 101 4e-21
BC113869-1|AAI13870.1| 795|Homo sapiens MARK1 protein protein. 101 4e-21
AL592406-3|CAH72463.1| 795|Homo sapiens MAP/microtubule affinit... 101 4e-21
AF154845-1|AAF72103.1| 795|Homo sapiens MARK protein. 101 4e-21
AY120867-1|AAM55491.1| 752|Homo sapiens MAP/microtubule affinit... 100 5e-21
AY057448-1|AAL23683.1| 752|Homo sapiens MARK4 serine/threonine ... 100 5e-21
AK075272-1|BAC11510.1| 752|Homo sapiens protein ( Homo sapiens ... 100 5e-21
AB058763-1|BAB47489.1| 689|Homo sapiens KIAA1860 protein protein. 100 5e-21
M80359-1|AAA59991.1| 713|Homo sapiens protein p78 protein. 100 6e-21
AF465413-1|AAL69982.1| 753|Homo sapiens MAP/microtubule affinit... 100 6e-21
BC017306-1|AAH17306.1| 628|Homo sapiens NUAK family, SNF1-like ... 100 1e-20
AK074830-1|BAC11234.1| 628|Homo sapiens protein ( Homo sapiens ... 100 1e-20
BC128510-1|AAI28511.1| 1203|Homo sapiens KIAA0999 protein protein. 99 2e-20
BC121188-1|AAI21189.1| 185|Homo sapiens KIAA0999 protein protein. 99 2e-20
AB088047-1|BAC03375.1| 752|Homo sapiens microtubule affinity-re... 99 2e-20
AB049127-1|BAB39380.1| 688|Homo sapiens MAP/microtubule affinit... 99 2e-20
AB023216-1|BAA76843.2| 1371|Homo sapiens KIAA0999 protein protein. 99 2e-20
AY505124-1|AAS86442.1| 778|Homo sapiens protein kinase SAD-B pr... 97 8e-20
AY458602-1|AAS10354.1| 778|Homo sapiens SAD1 kinase protein. 97 8e-20
AF479827-1|AAL87698.1| 778|Homo sapiens protein kinase-like pro... 97 8e-20
AF479826-1|AAL87697.1| 794|Homo sapiens putative serine/threoni... 97 8e-20
AY505125-1|AAS86443.1| 696|Homo sapiens protein kinase SAD-A pr... 96 1e-19
AY166857-1|AAN87839.1| 668|Homo sapiens serine/threonine protei... 96 1e-19
AF533880-1|AAP97727.1| 674|Homo sapiens putative serine/threoni... 96 1e-19
AF533879-1|AAP97726.1| 736|Homo sapiens putative serine/threoni... 96 1e-19
AF533878-1|AAP97725.1| 674|Homo sapiens putative serine/threoni... 96 1e-19
AF533877-1|AAP97724.1| 674|Homo sapiens putative serine/threoni... 96 1e-19
AF533876-1|AAP97723.1| 668|Homo sapiens putative serine/threoni... 96 1e-19
BC056423-1|AAH56423.1| 214|Homo sapiens ULK3 protein protein. 95 3e-19
BC036117-1|AAH36117.1| 214|Homo sapiens ULK3 protein protein. 95 3e-19
AB011109-1|BAA25463.2| 698|Homo sapiens KIAA0537 protein protein. 93 9e-19
AK131534-1|BAD18671.1| 766|Homo sapiens protein ( Homo sapiens ... 91 4e-18
BC037303-1|AAH37303.1| 550|Homo sapiens PRKAA1 protein protein. 91 5e-18
BC012622-1|AAH12622.1| 207|Homo sapiens PRKAA1 protein protein. 91 5e-18
AB022017-1|BAA36547.1| 550|Homo sapiens AMP-activated protein k... 91 5e-18
Y15056-1|CAA75341.1| 556|Homo sapiens PkB kinase protein. 89 1e-17
CR536517-1|CAG38755.1| 556|Homo sapiens PDPK1 protein. 89 1e-17
BC012103-1|AAH12103.1| 556|Homo sapiens 3-phosphoinositide depe... 89 1e-17
AF017995-1|AAC51825.1| 556|Homo sapiens 3-phosphoinositide depe... 89 1e-17
AC005591-1|AAC33797.1| 367|Homo sapiens PkB-like protein. 89 1e-17
AB209835-1|BAD93072.1| 492|Homo sapiens 3-phosphoinositide depe... 89 1e-17
EF056019-1|ABK30810.1| 552|Homo sapiens AMP-activated alpha 2 s... 88 3e-17
AJ785968-1|CAH05056.1| 396|Homo sapiens PDPK2 protein protein. 88 3e-17
AC005581-1|AAC33487.1| 462|Homo sapiens R31237_1, partial CDS p... 63 4e-17
U06454-1|AAA64745.1| 552|Homo sapiens AMP-activated protein kin... 87 5e-17
BC069823-1|AAH69823.1| 552|Homo sapiens AMP-activated protein k... 87 5e-17
BC069740-1|AAH69740.1| 552|Homo sapiens AMP-activated protein k... 87 5e-17
BC069680-1|AAH69680.1| 552|Homo sapiens protein kinase, AMP-act... 87 5e-17
AY714054-1|AAU04399.1| 306|Homo sapiens aurora-C protein. 87 5e-17
AY661554-1|AAT64422.1| 290|Homo sapiens aurora/Ipl1-related kin... 87 5e-17
AL035705-2|CAC17574.2| 552|Homo sapiens protein kinase, AMP-act... 87 5e-17
AB058714-1|BAB47440.1| 715|Homo sapiens KIAA1811 protein protein. 87 5e-17
AB017332-1|BAA76292.1| 309|Homo sapiens Aurora/Ipl1-related kin... 87 5e-17
AK222581-1|BAD96301.1| 556|Homo sapiens 3-phosphoinositide depe... 87 6e-17
BC063885-1|AAH63885.1| 708|Homo sapiens NIMA (never in mitosis ... 87 8e-17
AL139082-5|CAI12892.2| 708|Homo sapiens NIMA (never in mitosis ... 87 8e-17
AF054621-1|AAC25955.1| 309|Homo sapiens serine/threonine kinase... 87 8e-17
U22456-1|AAA64850.1| 174|Homo sapiens AMP-activated protein kin... 85 2e-16
BC075064-1|AAH75064.2| 275|Homo sapiens AURKC protein protein. 85 2e-16
AF059681-1|AAC77369.1| 275|Homo sapiens serine/threonine kinase... 85 3e-16
AJ271722-1|CAB71146.1| 714|Homo sapiens putative serine/threoni... 84 6e-16
AB006972-1|BAB69958.1| 970|Homo sapiens Sak protein. 84 6e-16
Y13115-1|CAA73575.1| 970|Homo sapiens serine/threonine protein ... 83 8e-16
BC036023-1|AAH36023.1| 970|Homo sapiens polo-like kinase 4 (Dro... 83 8e-16
D79997-1|BAA11492.2| 656|Homo sapiens KIAA0175 protein. 83 1e-15
BC014039-1|AAH14039.1| 651|Homo sapiens maternal embryonic leuc... 83 1e-15
AL442063-1|CAI16995.2| 651|Homo sapiens maternal embryonic leuc... 83 1e-15
AL354932-1|CAI11034.2| 651|Homo sapiens maternal embryonic leuc... 83 1e-15
AK222811-1|BAD96531.1| 651|Homo sapiens maternal embryonic leuc... 83 1e-15
BC036422-1|AAH36422.1| 436|Homo sapiens hypothetical protein MG... 82 2e-15
BC031231-1|AAH31231.1| 514|Homo sapiens serine/threonine kinase... 82 2e-15
AK093251-1|BAC04109.1| 514|Homo sapiens protein ( Homo sapiens ... 82 2e-15
AJ303380-1|CAC29064.1| 514|Homo sapiens serine/threonine kinase... 82 2e-15
BT019534-1|AAV38341.1| 344|Homo sapiens serine/threonine kinase... 80 9e-15
BC080581-1|AAH80581.1| 344|Homo sapiens aurora kinase B protein. 80 9e-15
BC013300-1|AAH13300.2| 371|Homo sapiens AURKB protein protein. 80 9e-15
BC009751-1|AAH09751.1| 344|Homo sapiens aurora kinase B protein. 80 9e-15
BC000442-1|AAH00442.3| 344|Homo sapiens aurora kinase B protein. 80 9e-15
AF159295-1|AAD48007.1| 752|Homo sapiens serine/threonine protei... 80 9e-15
AF008552-1|AAC12709.1| 344|Homo sapiens aurora-related kinase 2... 80 9e-15
AB011450-1|BAA32136.1| 344|Homo sapiens aurora and IPL1-like mi... 80 9e-15
AB011446-1|BAA82709.1| 343|Homo sapiens Aik2 protein. 80 9e-15
AB051552-1|BAB21856.1| 608|Homo sapiens KIAA1765 protein protein. 79 1e-14
D84212-1|BAA23592.1| 402|Homo sapiens aurora/IPL1-related kinas... 79 2e-14
BC111088-1|AAI11089.1| 252|Homo sapiens TSSK4 protein protein. 79 2e-14
BC027464-1|AAH27464.1| 403|Homo sapiens aurora kinase A protein. 79 2e-14
BC006423-1|AAH06423.1| 403|Homo sapiens aurora kinase A protein. 79 2e-14
BC002499-1|AAH02499.1| 403|Homo sapiens AURKA protein protein. 79 2e-14
BC001280-1|AAH01280.1| 403|Homo sapiens aurora kinase A protein. 79 2e-14
AL834498-1|CAD39156.1| 716|Homo sapiens hypothetical protein pr... 79 2e-14
AL121914-4|CAM45838.1| 347|Homo sapiens aurora kinase A protein. 79 2e-14
AL121914-3|CAC12717.1| 403|Homo sapiens aurora kinase A protein. 79 2e-14
AF195947-1|AAF29508.1| 403|Homo sapiens STK15 serine/threonine ... 79 2e-14
AF011468-1|AAC63902.1| 403|Homo sapiens serine/threonine kinase... 79 2e-14
AF008551-1|AAC12708.1| 403|Homo sapiens aurora-related kinase 1... 79 2e-14
AC093748-1|AAY40983.1| 443|Homo sapiens unknown protein. 79 2e-14
AB209181-1|BAD92418.1| 796|Homo sapiens Hypothetical protein DK... 79 2e-14
BC126432-1|AAI26433.1| 454|Homo sapiens death-associated protei... 79 2e-14
BC126430-1|AAI26431.1| 454|Homo sapiens death-associated protei... 79 2e-14
AB022341-1|BAA81746.1| 454|Homo sapiens ZIP kinase protein. 79 2e-14
AB007144-1|BAA24955.1| 454|Homo sapiens ZIP-kinase protein. 79 2e-14
AK027302-1|BAB55026.1| 208|Homo sapiens protein ( Homo sapiens ... 78 3e-14
AJ006701-1|CAA07196.1| 603|Homo sapiens putative serine/threoni... 78 3e-14
AC005793-1|AAC62830.1| 593|Homo sapiens KIAA0561 protein [AA 1-... 78 4e-14
AB011133-1|BAA25487.1| 1308|Homo sapiens KIAA0561 protein protein. 78 4e-14
BC034988-1|AAH34988.1| 1036|Homo sapiens ULK2 protein protein. 77 5e-14
BC028587-1|AAH28587.1| 482|Homo sapiens NEK11 protein protein. 77 5e-14
BC019916-1|AAH19916.2| 506|Homo sapiens NIMA (never in mitosis ... 77 5e-14
AL139082-7|CAI12895.1| 507|Homo sapiens NIMA (never in mitosis ... 77 5e-14
AK131359-1|BAD18511.1| 510|Homo sapiens protein ( Homo sapiens ... 77 5e-14
AB071997-1|BAC06351.1| 470|Homo sapiens NIMA-related kinase 11S... 77 5e-14
AB071996-1|BAC06350.1| 645|Homo sapiens NIMA-related kinase 11L... 77 5e-14
AB014523-1|BAA31598.2| 1100|Homo sapiens KIAA0623 protein protein. 77 5e-14
Y10256-1|CAA71306.1| 947|Homo sapiens NIK, serine/threonine pro... 77 7e-14
U08316-1|AAA81952.1| 740|Homo sapiens insulin-stimulated protei... 77 7e-14
L07599-1|AAC82495.1| 580|Homo sapiens ribosomal protein S6 kina... 77 7e-14
DQ314874-1|ABC40733.1| 947|Homo sapiens mitogen-activated prote... 77 7e-14
BC096302-1|AAH96302.1| 740|Homo sapiens ribosomal protein S6 ki... 77 7e-14
BC096301-1|AAH96301.1| 740|Homo sapiens ribosomal protein S6 ki... 77 7e-14
BC035576-1|AAH35576.1| 947|Homo sapiens mitogen-activated prote... 77 7e-14
AL807772-3|CAI39687.1| 740|Homo sapiens ribosomal protein S6 ki... 77 7e-14
AL807772-1|CAI39684.1| 227|Homo sapiens ribosomal protein S6 ki... 77 7e-14
AL732366-2|CAI40548.1| 740|Homo sapiens ribosomal protein S6 ki... 77 7e-14
AB208933-1|BAD92170.1| 806|Homo sapiens ribosomal protein S6 ki... 77 7e-14
AB102662-1|BAC81131.1| 726|Homo sapiens RPS6KA3 protein. 77 7e-14
AL121914-5|CAI19324.1| 271|Homo sapiens aurora kinase A protein. 77 9e-14
AD000092-1|AAB51171.1| 1237|Homo sapiens hypothetical human seri... 76 1e-13
AB023190-1|BAA76817.1| 1583|Homo sapiens KIAA0973 protein protein. 76 1e-13
Z98049-1|CAI20579.1| 733|Homo sapiens ribosomal protein S6 kina... 76 2e-13
X85106-1|CAA59427.1| 733|Homo sapiens ribosomal S6 kinase protein. 76 2e-13
L33881-1|AAB17011.1| 587|Homo sapiens protein kinase C iota pro... 76 2e-13
L20321-1|AAA36658.1| 841|Homo sapiens protein serine/threonine ... 76 2e-13
L18964-1|AAA60171.1| 587|Homo sapiens protein kinase C iota pro... 76 2e-13
L07598-1|AAC82496.1| 540|Homo sapiens ribosomal protein S6 kina... 76 2e-13
BC063044-1|AAH63044.1| 781|Homo sapiens NEK4 protein protein. 76 2e-13
BC048980-1|AAH48980.1| 574|Homo sapiens protein kinase, AMP-act... 76 2e-13
BC022016-1|AAH22016.3| 587|Homo sapiens protein kinase C, iota ... 76 2e-13
BC015515-1|AAH15515.1| 451|Homo sapiens Unknown (protein for IM... 76 2e-13
BC002363-1|AAH02363.1| 733|Homo sapiens ribosomal protein S6 ki... 76 2e-13
AL022069-2|CAI19651.1| 733|Homo sapiens ribosomal protein S6 ki... 76 2e-13
AB209116-1|BAD92353.1| 806|Homo sapiens ribosomal protein S6 ki... 76 2e-13
CR542227-1|CAG47023.1| 431|Homo sapiens STK24 protein. 75 2e-13
BT019619-1|AAV38425.1| 431|Homo sapiens serine/threonine kinase... 75 2e-13
BC096303-1|AAH96303.1| 740|Homo sapiens ribosomal protein S6 ki... 75 2e-13
BC065378-1|AAH65378.1| 431|Homo sapiens serine/threonine kinase... 75 2e-13
BC035578-1|AAH35578.1| 431|Homo sapiens serine/threonine kinase... 75 2e-13
AL356423-3|CAI13115.1| 431|Homo sapiens serine/threonine kinase... 75 2e-13
AL356423-2|CAI13114.1| 443|Homo sapiens serine/threonine kinase... 75 2e-13
AL137249-7|CAI39457.1| 431|Homo sapiens serine/threonine kinase... 75 2e-13
AL137249-3|CAI39453.1| 443|Homo sapiens serine/threonine kinase... 75 2e-13
AF083420-1|AAD42039.1| 443|Homo sapiens brain-specific STE20-li... 75 2e-13
AF024636-1|AAB82560.1| 431|Homo sapiens STE20-like kinase 3 pro... 75 2e-13
AB183427-1|BAF73615.1| 619|Homo sapiens maternal embryonic leuc... 75 2e-13
Z84486-1|CAI21678.1| 526|Homo sapiens serum/glucocorticoid regu... 75 3e-13
Y10032-1|CAA71138.1| 431|Homo sapiens serine/threonine protein ... 75 3e-13
X76104-1|CAA53712.1| 1431|Homo sapiens DAP-kinase protein. 75 3e-13
EF560744-1|ABQ59054.1| 841|Homo sapiens NEK4 protein protein. 75 3e-13
DQ436495-1|ABD96827.1| 1430|Homo sapiens death-associated protei... 75 3e-13
BT006935-1|AAP35581.1| 367|Homo sapiens death-associated protei... 75 3e-13
BC113660-1|AAI13661.1| 1430|Homo sapiens death-associated protei... 75 3e-13
BC001263-1|AAH01263.1| 431|Homo sapiens serum/glucocorticoid re... 75 3e-13
AL591852-1|CAH71696.1| 1455|Homo sapiens death-associated protei... 75 3e-13
AL355881-2|CAH72579.1| 526|Homo sapiens serum/glucocorticoid re... 75 3e-13
AL161787-1|CAH73544.1| 1455|Homo sapiens death-associated protei... 75 3e-13
AL160279-1|CAI16306.1| 1455|Homo sapiens death-associated protei... 75 3e-13
AL135839-4|CAI19721.1| 526|Homo sapiens serum/glucocorticoid re... 75 3e-13
AL135839-3|CAI19720.1| 445|Homo sapiens serum/glucocorticoid re... 75 3e-13
AL135839-2|CAI19719.1| 431|Homo sapiens serum/glucocorticoid re... 75 3e-13
AL135839-1|CAI19718.1| 421|Homo sapiens serum/glucocorticoid re... 75 3e-13
AJ000512-1|CAA04146.1| 431|Homo sapiens serine/threonine protei... 75 3e-13
AF153609-1|AAD41091.1| 431|Homo sapiens serine/threonine protei... 75 3e-13
AF045458-1|AAC32326.1| 1050|Homo sapiens serine/threonine kinase... 75 3e-13
AB208871-1|BAD92108.1| 1433|Homo sapiens Hypothetical protein DK... 75 3e-13
AB072828-1|BAC15599.1| 489|Homo sapiens NIMA-related protein ki... 75 3e-13
AB018265-1|BAA34442.2| 1066|Homo sapiens KIAA0722 protein protein. 75 3e-13
AY830839-1|AAW52510.1| 2434|Homo sapiens serine/threonine protei... 75 4e-13
AB033104-1|BAA86592.1| 1311|Homo sapiens KIAA1278 protein protein. 75 4e-13
AB002301-1|BAA20762.1| 2137|Homo sapiens KIAA0303 protein. 75 4e-13
BC006106-1|AAH06106.3| 482|Homo sapiens ribosomal protein S6 ki... 74 5e-13
BC000094-1|AAH00094.3| 482|Homo sapiens ribosomal protein S6 ki... 74 5e-13
AF099739-1|AAD20990.1| 482|Homo sapiens S6 kinase-related kinas... 74 5e-13
AF076931-1|AAD46063.1| 482|Homo sapiens serine/threonine kinase... 74 5e-13
AB016869-1|BAA34402.1| 495|Homo sapiens p70 ribosomal S6 kinase... 74 5e-13
AL390029-2|CAI15721.1| 740|Homo sapiens doublecortin and CaM ki... 74 6e-13
AL390029-1|CAI15720.1| 729|Homo sapiens doublecortin and CaM ki... 74 6e-13
AL160392-2|CAH70261.1| 740|Homo sapiens doublecortin and CaM ki... 74 6e-13
AL160392-1|CAH70262.1| 729|Homo sapiens doublecortin and CaM ki... 74 6e-13
AL157760-4|CAH70170.1| 433|Homo sapiens doublecortin and CaM ki... 74 6e-13
AL157760-2|CAH70167.1| 740|Homo sapiens doublecortin and CaM ki... 74 6e-13
AL157760-1|CAH70168.1| 729|Homo sapiens doublecortin and CaM ki... 74 6e-13
AL157694-2|CAH70656.1| 740|Homo sapiens doublecortin and CaM ki... 74 6e-13
AL157694-1|CAH70657.1| 729|Homo sapiens doublecortin and CaM ki... 74 6e-13
AK075004-1|BAC11348.1| 423|Homo sapiens protein ( Homo sapiens ... 74 6e-13
AF239798-1|AAF63496.1| 619|Homo sapiens protein kinase MEKK2b p... 74 6e-13
AB208963-1|BAD92200.1| 621|Homo sapiens Protein kinase MEKK2b v... 74 6e-13
AB002367-1|BAA20824.2| 794|Homo sapiens KIAA0369 protein. 74 6e-13
X99325-1|CAA67700.1| 426|Homo sapiens Ste20-like kinase protein. 73 8e-13
D63780-1|BAA20420.1| 426|Homo sapiens YSK1 protein. 73 8e-13
DQ093965-1|AAY88740.1| 426|Homo sapiens serine/threonine kinase... 73 8e-13
BT019961-1|AAV38764.1| 426|Homo sapiens serine/threonine kinase... 73 8e-13
BC091505-1|AAH91505.1| 426|Homo sapiens STK25 protein protein. 73 8e-13
BC015793-1|AAH15793.1| 426|Homo sapiens STK25 protein protein. 73 8e-13
BC007852-1|AAH07852.1| 426|Homo sapiens serine/threonine kinase... 73 8e-13
AC110926-2|AAY15070.1| 270|Homo sapiens unknown protein. 73 8e-13
AC110299-2|AAY14683.1| 426|Homo sapiens unknown protein. 73 8e-13
AB209475-1|BAD92712.1| 461|Homo sapiens protein kinase C, alpha... 73 8e-13
X52479-1|CAA36718.1| 672|Homo sapiens protein ( Human PKC alpha... 73 1e-12
BC109274-1|AAI09275.1| 672|Homo sapiens protein kinase C, alpha... 73 1e-12
BC109273-1|AAI09274.1| 672|Homo sapiens protein kinase C, alpha... 73 1e-12
BC065499-1|AAH65499.1| 1797|Homo sapiens microtubule associated ... 73 1e-12
BC015816-1|AAH15816.2| 792|Homo sapiens MAST2 protein protein. 73 1e-12
BC006166-1|AAH06166.1| 792|Homo sapiens MAST2 protein protein. 73 1e-12
AY633609-1|AAV33302.1| 672|Homo sapiens aging-associated gene 6... 73 1e-12
AL645480-2|CAH73245.1| 792|Homo sapiens microtubule associated ... 73 1e-12
AL645480-1|CAH73244.1| 1798|Homo sapiens microtubule associated ... 73 1e-12
AL603888-3|CAI16563.1| 792|Homo sapiens microtubule associated ... 73 1e-12
AL603888-2|CAI16562.1| 1798|Homo sapiens microtubule associated ... 73 1e-12
AL603882-2|CAI16217.1| 1798|Homo sapiens microtubule associated ... 73 1e-12
AL358075-6|CAI21706.1| 792|Homo sapiens microtubule associated ... 73 1e-12
AL358075-5|CAI21705.1| 1798|Homo sapiens microtubule associated ... 73 1e-12
AF015254-1|AAC98891.1| 347|Homo sapiens serine/threonine kinase... 73 1e-12
AB047005-1|BAB40778.1| 1734|Homo sapiens MAST205 protein. 73 1e-12
AB018350-1|BAA34527.2| 1329|Homo sapiens KIAA0807 protein protein. 73 1e-12
M60725-1|AAA36411.1| 502|Homo sapiens p70 ribosomal S6 kinase a... 73 1e-12
M60724-1|AAA36410.1| 525|Homo sapiens p70 ribosomal S6 kinase a... 73 1e-12
BT020099-1|AAV38902.1| 416|Homo sapiens Mst3 and SOK1-related k... 73 1e-12
BC114506-1|AAI14507.1| 370|Homo sapiens death-associated protei... 73 1e-12
BC103503-1|AAI03504.1| 416|Homo sapiens serine/threonine protei... 73 1e-12
BC099843-1|AAH99843.1| 416|Homo sapiens serine/threonine protei... 73 1e-12
BC098315-1|AAH98315.1| 416|Homo sapiens serine/threonine protei... 73 1e-12
BC053365-1|AAH53365.1| 451|Homo sapiens RPS6KB1 protein protein. 73 1e-12
BC026158-1|AAH26158.1| 1315|Homo sapiens serine/threonine kinase... 73 1e-12
BC017575-1|AAH17575.1| 476|Homo sapiens CHK1 checkpoint homolog... 73 1e-12
BC004202-1|AAH04202.1| 476|Homo sapiens CHEK1 protein protein. 73 1e-12
AL109749-1|CAI42079.1| 416|Homo sapiens Mst3 and SOK1-related k... 73 1e-12
AK075150-1|BAC11435.1| 392|Homo sapiens protein ( Homo sapiens ... 73 1e-12
AF527555-1|AAM78553.1| 476|Homo sapiens CHK1 checkpoint homolog... 73 1e-12
AF344883-1|AAK29621.1| 354|Homo sapiens serine/threonine protei... 73 1e-12
AF344882-1|AAK29620.1| 416|Homo sapiens serine/threonine protei... 73 1e-12
AF231012-1|AAK38484.1| 416|Homo sapiens STE20-like kinase MST4 ... 73 1e-12
AF200815-1|AAF97028.1| 1315|Homo sapiens FUSED serine/threonine ... 73 1e-12
AF111105-1|AAD28547.1| 618|Homo sapiens mitogen-activated prote... 73 1e-12
AF052941-1|AAC35001.1| 370|Homo sapiens DAP-kinase related prot... 73 1e-12
AF032874-1|AAB88852.1| 476|Homo sapiens protein kinase protein. 73 1e-12
AF016582-1|AAC51736.1| 476|Homo sapiens Chk1 protein. 73 1e-12
AB040057-1|BAA92785.2| 416|Homo sapiens serine/threonine protei... 73 1e-12
AB032387-1|BAA84577.1| 476|Homo sapiens checkpoint kinase protein. 73 1e-12
AB018001-1|BAA88063.1| 370|Homo sapiens Death-associated protei... 73 1e-12
D43636-1|BAA07744.2| 766|Homo sapiens KIAA0096 protein. 72 2e-12
BC071567-1|AAH71567.1| 765|Homo sapiens SNRK protein protein. 72 2e-12
BC013879-1|AAH13879.1| 685|Homo sapiens polo-like kinase 2 (Dro... 72 2e-12
AK098163-1|BAC05247.1| 372|Homo sapiens protein ( Homo sapiens ... 72 2e-12
AK000231-1|BAA91023.1| 244|Homo sapiens protein ( Homo sapiens ... 72 2e-12
AF223574-1|AAF62897.1| 685|Homo sapiens serum-inducible kinase ... 72 2e-12
AF059617-1|AAC14573.1| 685|Homo sapiens serum-inducible kinase ... 72 2e-12
Z15108-1|CAA78813.1| 584|Homo sapiens protein kinase C zeta pro... 72 2e-12
L07597-1|AAC82497.1| 735|Homo sapiens ribosomal protein S6 kina... 72 2e-12
BT007082-1|AAP35745.1| 592|Homo sapiens protein kinase C, zeta ... 72 2e-12
BC014966-1|AAH14966.1| 735|Homo sapiens ribosomal protein S6 ki... 72 2e-12
BC014270-1|AAH14270.1| 592|Homo sapiens protein kinase C, zeta ... 72 2e-12
BC008058-1|AAH08058.1| 592|Homo sapiens protein kinase C, zeta ... 72 2e-12
AL645703-1|CAI21535.1| 592|Homo sapiens protein kinase C, zeta ... 72 2e-12
AL627313-6|CAI14649.1| 735|Homo sapiens ribosomal protein S6 ki... 72 2e-12
AL590822-9|CAI12484.1| 592|Homo sapiens protein kinase C, zeta ... 72 2e-12
AL391845-5|CAI15438.1| 592|Homo sapiens protein kinase C, zeta ... 72 2e-12
AB019245-1|BAA37145.1| 481|Homo sapiens S6 kinase b protein. 72 2e-12
U78876-1|AAB41729.1| 626|Homo sapiens MEK kinase 3 protein. 71 3e-12
DQ454151-1|ABE11554.1| 622|Homo sapiens mitogen-activated prote... 71 3e-12
BC093674-1|AAH93674.1| 626|Homo sapiens mitogen-activated prote... 71 3e-12
BC093672-1|AAH93672.1| 626|Homo sapiens mitogen-activated prote... 71 3e-12
BC090859-1|AAH90859.1| 626|Homo sapiens mitogen-activated prote... 71 3e-12
BC008336-1|AAH08336.1| 594|Homo sapiens Unknown (protein for IM... 71 3e-12
AK058166-1|BAB71697.1| 128|Homo sapiens protein ( Homo sapiens ... 71 3e-12
AF004022-1|AAB65786.1| 347|Homo sapiens protein kinase protein. 71 3e-12
L14283-1|AAA36488.1| 592|Homo sapiens protein kinase C zeta pro... 71 6e-12
Z29067-1|CAA82310.1| 459|Homo sapiens protein kinase protein. 70 8e-12
CR456418-1|CAG30304.1| 586|Homo sapiens CHEK2 protein. 70 8e-12
BC004207-1|AAH04207.1| 543|Homo sapiens CHK2 checkpoint homolog... 70 8e-12
AY800241-1|AAV41895.1| 543|Homo sapiens CHK2 checkpoint homolog... 70 8e-12
AY551303-1|AAS58464.1| 452|Homo sapiens protein kinase Chk2 tra... 70 8e-12
AY551297-1|AAS58458.1| 586|Homo sapiens protein kinase Chk2 tra... 70 8e-12
AL121825-1|CAH73823.1| 543|Homo sapiens CHK2 checkpoint homolog... 70 8e-12
AL117330-1|CAH73875.1| 543|Homo sapiens CHK2 checkpoint homolog... 70 8e-12
AJ131197-1|CAA10319.1| 543|Homo sapiens protein kinase protein. 70 8e-12
AF226044-1|AAF86944.1| 765|Homo sapiens HSNFRK protein. 70 8e-12
AF174135-1|AAD48504.1| 543|Homo sapiens protein kinase CHK2 pro... 70 8e-12
AF096279-1|AAD11784.1| 543|Homo sapiens HuCds1 kinase protein. 70 8e-12
AF086904-1|AAC83693.1| 543|Homo sapiens protein kinase Chk2 pro... 70 8e-12
X73458-1|CAA51837.1| 603|Homo sapiens protein kinase protein. 69 1e-11
BC014846-1|AAH14846.1| 603|Homo sapiens polo-like kinase 1 (Dro... 69 1e-11
BC003002-1|AAH03002.1| 603|Homo sapiens polo-like kinase 1 (Dro... 69 1e-11
BC002369-1|AAH02369.1| 603|Homo sapiens polo-like kinase 1 (Dro... 69 1e-11
AB084459-1|BAD93352.1| 247|Homo sapiens polo-like kinase 1 delt... 69 1e-11
AY874862-1|AAX59898.1| 424|Homo sapiens SH3-binding kinase prot... 69 2e-11
AL592406-2|CAH72462.1| 758|Homo sapiens MAP/microtubule affinit... 69 2e-11
AK074578-1|BAC11070.1| 426|Homo sapiens protein ( Homo sapiens ... 69 2e-11
AF125808-1|AAF19762.1| 318|Homo sapiens ETS related protein-neu... 69 2e-11
AF041811-1|AAC12728.2| 408|Homo sapiens ETS related protein-gro... 69 2e-11
AB040910-1|BAA96001.1| 870|Homo sapiens KIAA1477 protein protein. 69 2e-11
D87931-1|BAA75636.1| 1388|Homo sapiens Rho kinase protein. 69 2e-11
CR536581-1|CAG38818.1| 429|Homo sapiens SGKL protein. 69 2e-11
BC015326-1|AAH15326.1| 496|Homo sapiens serum/glucocorticoid re... 69 2e-11
AL389887-1|CAC16111.2| 745|Homo sapiens ribosomal protein S6 ki... 69 2e-11
AL354653-1|CAD13486.2| 745|Homo sapiens ribosomal protein S6 ki... 69 2e-11
AK223523-1|BAD97243.1| 496|Homo sapiens serum/glucocorticoid re... 69 2e-11
AF184965-1|AAF13190.1| 745|Homo sapiens ribosomal S6 kinase pro... 69 2e-11
AF169035-1|AAF12758.1| 429|Homo sapiens protein kinase protein. 69 2e-11
AC018463-2|AAX93049.1| 1337|Homo sapiens unknown protein. 69 2e-11
AB014519-1|BAA31594.2| 1428|Homo sapiens KIAA0619 protein protein. 69 2e-11
U43195-1|AAB02814.1| 1354|Homo sapiens Rho-associated, coiled-co... 68 3e-11
U24153-1|AAA65442.1| 525|Homo sapiens p21-activated protein kin... 68 3e-11
L19559-1|AAA36659.1| 603|Homo sapiens protein kinase protein. 68 3e-11
L07032-1|AAA60101.1| 706|Homo sapiens protein kinase C-theta pr... 68 3e-11
L01087-1|AAA75571.1| 706|Homo sapiens protein kinase C-theta pr... 68 3e-11
BC113359-1|AAI13360.1| 706|Homo sapiens protein kinase C, theta... 68 3e-11
BC101465-1|AAI01466.1| 706|Homo sapiens protein kinase C, theta... 68 3e-11
BC032787-1|AAH32787.1| 476|Homo sapiens calcium/calmodulin-depe... 68 3e-11
AY702977-1|AAU29340.1| 643|Homo sapiens protein kinase C theta ... 68 3e-11
AY212935-1|AAP29964.1| 460|Homo sapiens CLICK III protein. 68 3e-11
AL158043-2|CAC12904.2| 706|Homo sapiens protein kinase C, theta... 68 3e-11
AL158043-1|CAI16127.1| 478|Homo sapiens protein kinase C, theta... 68 3e-11
AL137145-2|CAC10200.2| 706|Homo sapiens protein kinase C, theta... 68 3e-11
AL137145-1|CAI15756.1| 478|Homo sapiens protein kinase C, theta... 68 3e-11
AL049688-1|CAB41259.1| 481|Homo sapiens hypothetical protein pr... 68 3e-11
AL023754-3|CAI19991.1| 476|Homo sapiens calcium/calmodulin-depe... 68 3e-11
AL023754-2|CAI19990.1| 245|Homo sapiens calcium/calmodulin-depe... 68 3e-11
AK027493-1|BAB55152.1| 638|Homo sapiens protein ( Homo sapiens ... 68 3e-11
AF428261-1|AAL28100.1| 476|Homo sapiens calcium/calmodulin-depe... 68 3e-11
X75932-1|CAA53536.1| 603|Homo sapiens Serine/Threonine protein ... 68 4e-11
U56998-1|AAC50637.1| 607|Homo sapiens putative serine/threonine... 68 4e-11
L41816-1|AAA99458.1| 370|Homo sapiens cam kinase I protein. 68 4e-11
BC106755-1|AAI06756.1| 370|Homo sapiens calcium/calmodulin-depe... 68 4e-11
BC106754-1|AAI06755.1| 370|Homo sapiens calcium/calmodulin-depe... 68 4e-11
BC013899-1|AAH13899.1| 646|Homo sapiens polo-like kinase 3 (Dro... 68 4e-11
AY764184-1|AAU88146.1| 646|Homo sapiens polo-like kinase 3 (Dro... 68 4e-11
AL627313-4|CAI14647.1| 578|Homo sapiens ribosomal protein S6 ki... 68 4e-11
AL592166-11|CAI13006.1| 646|Homo sapiens polo-like kinase 3 (Dr... 68 4e-11
AB209875-1|BAD93112.1| 621|Homo sapiens polo-like kinase 3 vari... 68 4e-11
X65293-1|CAA46388.1| 737|Homo sapiens protein kinase C epsilon... 67 5e-11
U01038-1|AAA56634.1| 603|Homo sapiens pLK protein. 67 5e-11
BC114491-1|AAI14492.1| 1189|Homo sapiens NEK1 protein protein. 67 5e-11
BC109034-1|AAI09035.1| 737|Homo sapiens protein kinase C, epsil... 67 5e-11
BC109033-1|AAI09034.1| 737|Homo sapiens protein kinase C, epsil... 67 5e-11
BC015147-1|AAH15147.1| 403|Homo sapiens Unknown (protein for IM... 67 5e-11
AJ293866-1|CAC10659.1| 646|Homo sapiens FNK serine/threonine pr... 67 5e-11
AB067488-1|BAB67794.1| 1265|Homo sapiens KIAA1901 protein protein. 67 5e-11
X66364-1|CAA47007.1| 292|Homo sapiens serine/threonine protein ... 67 7e-11
M34182-1|AAC41690.1| 360|Homo sapiens protein kinase A gamma-su... 67 7e-11
L07861-1|AAA03175.1| 676|Homo sapiens protein kinase C-delta 13... 67 7e-11
D10495-1|BAA01381.1| 626|Homo sapiens protein kinase C delta-ty... 67 7e-11
DQ667175-1|ABG25920.1| 351|Homo sapiens protein kinase, cAMP-de... 67 7e-11
BT006680-1|AAP35326.1| 292|Homo sapiens cyclin-dependent kinase... 67 7e-11
BC043350-1|AAH43350.1| 676|Homo sapiens protein kinase C, delta... 67 7e-11
BC039888-1|AAH39888.1| 351|Homo sapiens protein kinase, cAMP-de... 67 7e-11
BC005115-1|AAH05115.1| 292|Homo sapiens cyclin-dependent kinase... 67 7e-11
AY049778-1|AAL15435.1| 292|Homo sapiens cyclin-dependent kinase... 67 7e-11
AL162730-1|CAH71828.1| 351|Homo sapiens protein kinase, cAMP-de... 67 7e-11
AJ001597-1|CAA04863.1| 351|Homo sapiens cAMP-dependent protein ... 67 7e-11
AF085233-1|AAF27051.2| 496|Homo sapiens SGK-like protein SGKL p... 67 7e-11
X07767-1|CAA30597.1| 351|Homo sapiens protein ( Human mRNA for ... 66 9e-11
S76475-1|AAB33111.1| 839|Homo sapiens trkC protein. 66 9e-11
M80335-1|AAA60094.1| 207|Homo sapiens protein kinase A-alpha pr... 66 9e-11
DQ667173-1|ABG25918.1| 351|Homo sapiens protein kinase, cAMP-de... 66 9e-11
DQ201638-1|ABA27097.1| 527|Homo sapiens oxidative-stress respon... 66 9e-11
BC108259-1|AAI08260.1| 351|Homo sapiens protein kinase, cAMP-de... 66 9e-11
BC062616-1|AAH62616.1| 424|Homo sapiens protein serine kinase H... 66 9e-11
BC039846-1|AAH39846.1| 351|Homo sapiens protein kinase, cAMP-de... 66 9e-11
BC008726-1|AAH08726.1| 527|Homo sapiens oxidative-stress respon... 66 9e-11
AJ272212-1|CAB91984.1| 424|Homo sapiens protein serine kinase p... 66 9e-11
AJ224521-1|CAA12029.1| 839|Homo sapiens TRKC protein. 66 9e-11
AF217975-1|AAG17218.1| 322|Homo sapiens unknown protein. 66 9e-11
AF208004-1|AAG35720.1| 181|Homo sapiens cAMP-dependent protein ... 66 9e-11
AB017642-1|BAA75674.1| 527|Homo sapiens oxidative-stress respon... 66 9e-11
U63333-1|AAB05809.1| 433|Homo sapiens serine/threonine protein ... 66 1e-10
L13616-1|AAA58469.1| 1052|Homo sapiens focal adhesion kinase pro... 66 1e-10
L07860-1|AAA03176.1| 676|Homo sapiens protein kinase C-delta 13... 66 1e-10
BC038238-1|AAH38238.1| 414|Homo sapiens serine/threonine kinase... 66 1e-10
BC035404-1|AAH35404.1| 1006|Homo sapiens PTK2 protein protein. 66 1e-10
BC028733-1|AAH28733.1| 680|Homo sapiens PTK2 protein protein. 66 1e-10
BC019334-1|AAH19334.1| 433|Homo sapiens serine/threonine kinase... 66 1e-10
BC007981-1|AAH07981.1| 433|Homo sapiens serine/threonine kinase... 66 1e-10
AK094999-1|BAC04470.1| 720|Homo sapiens protein ( Homo sapiens ... 66 1e-10
AJ250839-1|CAB76471.1| 414|Homo sapiens serine/threonine protei... 66 1e-10
AF217978-1|AAG17221.1| 433|Homo sapiens unknown protein. 66 1e-10
AF055327-1|AAC15742.1| 433|Homo sapiens Peutz-Jeghers syndrome ... 66 1e-10
AF035625-1|AAC39527.1| 433|Homo sapiens serine threonine kinase... 66 1e-10
AF032986-1|AAB97833.1| 433|Homo sapiens serine threonine kinase... 66 1e-10
AB209553-1|BAD92790.1| 337|Homo sapiens serine/threonine protei... 66 1e-10
AB209083-1|BAD92320.1| 1007|Homo sapiens PTK2 protein tyrosine k... 66 1e-10
AB209071-1|BAD92308.1| 975|Homo sapiens PTK2 protein tyrosine k... 66 1e-10
Y15801-1|CAA75792.1| 277|Homo sapiens protein kinase protein. 66 2e-10
Y13927-1|CAA74244.1| 277|Homo sapiens protein kinase protein. 66 2e-10
CR536566-1|CAG38803.1| 745|Homo sapiens RPS6KA6 protein. 66 2e-10
BC074852-1|AAH74852.1| 277|Homo sapiens protein kinase, Y-linke... 66 2e-10
BC074851-1|AAH74851.1| 277|Homo sapiens protein kinase, Y-linke... 66 2e-10
AY098866-1|AAM21719.1| 486|Homo sapiens PKE protein kinase prot... 66 2e-10
AL590105-1|CAI13011.1| 486|Homo sapiens protein kinase (PKE) pr... 66 2e-10
AL512622-1|CAI12181.1| 486|Homo sapiens protein kinase (PKE) pr... 66 2e-10
AB020641-1|BAA74857.2| 453|Homo sapiens KIAA0834 protein protein. 66 2e-10
X85545-1|CAA59733.1| 358|Homo sapiens protein kinase protein. 65 3e-10
U85755-1|AAD00575.1| 299|Homo sapiens serum-inducible kinase pr... 65 3e-10
CR457041-1|CAG33322.1| 292|Homo sapiens CDK5 protein. 65 3e-10
BT020098-1|AAV38901.1| 367|Homo sapiens serum/glucocorticoid re... 65 3e-10
BC041073-1|AAH41073.1| 358|Homo sapiens protein kinase, X-linke... 65 3e-10
BC037268-1|AAH37268.1| 683|Homo sapiens protein kinase C, eta p... 65 3e-10
AF119833-1|AAG43234.1| 469|Homo sapiens serine/threonine protei... 65 3e-10
AB062450-1|BAB85632.1| 302|Homo sapiens NEK7 protein. 65 3e-10
X74764-1|CAA52777.1| 855|Homo sapiens protein-tyrosine kinase p... 64 4e-10
X07109-1|CAA30130.1| 673|Homo sapiens protein ( Human mRNA for ... 64 4e-10
X06318-1|CAA29634.1| 671|Homo sapiens protein ( Human mRNA for ... 64 4e-10
M13975-1|AAA60095.1| 673|Homo sapiens protein kinase C beta-II ... 64 4e-10
BC036472-1|AAH36472.1| 673|Homo sapiens protein kinase C, beta ... 64 4e-10
AK131198-1|BAD18393.1| 706|Homo sapiens protein ( Homo sapiens ... 64 4e-10
AC002299-2|AAB97934.1| 496|Homo sapiens Protein kinase C beta (... 64 4e-10
AC002299-1|AAB97933.1| 494|Homo sapiens Protein kinase C beta (... 64 4e-10
Z98752-8|CAC18509.1| 367|Homo sapiens serum/glucocorticoid regu... 64 5e-10
Z98752-5|CAI42312.1| 427|Homo sapiens serum/glucocorticoid regu... 64 5e-10
Z97989-6|CAI22299.1| 485|Homo sapiens FYN oncogene related to S... 64 5e-10
Z97989-5|CAI22301.1| 534|Homo sapiens FYN oncogene related to S... 64 5e-10
X75756-1|CAA53384.1| 912|Homo sapiens protein kinase C mu protein. 64 5e-10
X66358-1|CAA47002.1| 358|Homo sapiens serine/threonine protein ... 64 5e-10
S74774-1|AAB33113.2| 534|Homo sapiens tyrosine kinase p59fyn(T)... 64 5e-10
M34181-1|AAA60170.1| 351|Homo sapiens cAMP-dependent protein ki... 64 5e-10
EF644172-1|ABR45718.1| 433|Homo sapiens polarization-related pr... 64 5e-10
DQ667174-1|ABG25919.1| 398|Homo sapiens protein kinase, cAMP-de... 64 5e-10
DQ485452-1|ABE96833.1| 914|Homo sapiens protein kinase D1 protein. 64 5e-10
BC104977-1|AAI04978.1| 358|Homo sapiens cyclin-dependent kinase... 64 5e-10
BC065511-1|AAH65511.1| 367|Homo sapiens SGK2 protein protein. 64 5e-10
BC016285-1|AAH16285.1| 257|Homo sapiens protein kinase, cAMP-de... 64 5e-10
BC014037-1|AAH14037.3| 367|Homo sapiens serum/glucocorticoid re... 64 5e-10
AY525548-1|AAS00095.1| 358|Homo sapiens cyclin-dependent kinase... 64 5e-10
AL450063-11|CAI16854.1| 264|Homo sapiens protein kinase, cAMP-d... 64 5e-10
AL450063-10|CAI16853.1| 209|Homo sapiens protein kinase, cAMP-d... 64 5e-10
AL450063-9|CAI16852.1| 197|Homo sapiens protein kinase, cAMP-de... 64 5e-10
AL450063-8|CAI16851.1| 206|Homo sapiens protein kinase, cAMP-de... 64 5e-10
AL450063-7|CAI16850.1| 245|Homo sapiens protein kinase, cAMP-de... 64 5e-10
AL450063-6|CAI16849.1| 214|Homo sapiens protein kinase, cAMP-de... 64 5e-10
AL450063-5|CAI16848.1| 186|Homo sapiens protein kinase, cAMP-de... 64 5e-10
AL450063-3|CAI16846.1| 398|Homo sapiens protein kinase, cAMP-de... 64 5e-10
AL450063-2|CAI16845.1| 351|Homo sapiens protein kinase, cAMP-de... 64 5e-10
AL450063-1|CAI16844.1| 257|Homo sapiens protein kinase, cAMP-de... 64 5e-10
AL359504-2|CAI14541.1| 351|Homo sapiens protein kinase, cAMP-de... 64 5e-10
AL359504-1|CAI14540.1| 257|Homo sapiens protein kinase, cAMP-de... 64 5e-10
AF186470-1|AAG17012.1| 427|Homo sapiens protein kinase protein. 64 5e-10
AF169034-1|AAF12757.2| 367|Homo sapiens protein kinase protein. 64 5e-10
AB209189-1|BAD92426.1| 365|Homo sapiens cAMP-dependent protein ... 64 5e-10
M95936-1|AAA58364.1| 481|Homo sapiens protein serine/threonine ... 64 7e-10
M77198-1|AAA36585.1| 520|Homo sapiens rac protein kinase-beta p... 64 7e-10
M55284-1|AAA60100.1| 682|Homo sapiens protein kinase C-L protein. 64 7e-10
L07868-1|AAB59446.1| 1308|Homo sapiens receptor tyrosine kinase ... 64 7e-10
BC120994-1|AAI20995.1| 481|Homo sapiens v-akt murine thymoma vi... 64 7e-10
BC113114-1|AAI13115.1| 1354|Homo sapiens Rho-associated, coiled-... 64 7e-10
BC112199-1|AAI12200.1| 1308|Homo sapiens v-erb-a erythroblastic ... 64 7e-10
BC032709-1|AAH32709.1| 344|Homo sapiens AKT2 protein protein. 64 7e-10
AF164041-1|AAD50272.1| 1130|Homo sapiens WARTS protein kinase pr... 64 7e-10
AF104413-1|AAD16882.1| 1130|Homo sapiens large tumor suppressor ... 64 7e-10
AB209697-1|BAD92934.1| 892|Homo sapiens v-erb-a erythroblastic ... 64 7e-10
AB209426-1|BAD92663.1| 830|Homo sapiens LATS homolog 1 variant ... 64 7e-10
Z98752-7|CAI42315.1| 366|Homo sapiens serum/glucocorticoid regu... 63 9e-10
Z98752-6|CAI42313.1| 198|Homo sapiens serum/glucocorticoid regu... 63 9e-10
X66363-1|CAA47006.1| 496|Homo sapiens serine/threonine protein ... 63 9e-10
X66360-1|CAA47004.1| 523|Homo sapiens serine/threonine protein ... 63 9e-10
J03358-1|AAA61190.1| 822|Homo sapiens FER protein. 63 9e-10
BT006827-1|AAP35473.1| 496|Homo sapiens PCTAIRE protein kinase ... 63 9e-10
BC053878-1|AAH53878.1| 619|Homo sapiens zeta-chain (TCR) associ... 63 9e-10
BC052998-1|AAH52998.1| 855|Homo sapiens discoidin domain recept... 63 9e-10
BC039039-1|AAH39039.1| 493|Homo sapiens ZAP70 protein protein. 63 9e-10
>CR456587-1|CAG30473.1| 358|Homo sapiens STK22A protein.
Length = 358
Score = 135 bits (327), Expect = 1e-31
Identities = 64/155 (41%), Positives = 100/155 (64%), Gaps = 1/155 (0%)
Frame = +1
Query: 271 EVNALEQRGYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFP 450
+ L ++GY++G +G+GSYA V A S + ++A KI D++K P DF+E+F P
Sbjct: 3 DATVLRKKGYIVGINLGKGSYAKVKSAY----SERLKFNVAVKIIDRKKTPTDFVERFLP 58
Query: 451 RELEILTKIENPHIIQVHSILQRGP-RVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFR 627
RE++IL + + II+ + I + R++I M GDLL+FIK G + E+ A+ FR
Sbjct: 59 REMDILATVNHGSIIKTYEIFETSDGRIYIIMELGVQGDLLEFIKCQGALHEDVARKMFR 118
Query: 628 QMASGLQYLHSKNIAHRDLKCENILLSRRFNVKLA 732
Q++S ++Y H +I HRDLKCEN+LL + FN+KL+
Sbjct: 119 QLSSAVKYCHDLDIVHRDLKCENLLLDKDFNIKLS 153
>BC037781-1|AAH37781.1| 358|Homo sapiens testis-specific serine
kinase 2 protein.
Length = 358
Score = 135 bits (327), Expect = 1e-31
Identities = 64/155 (41%), Positives = 100/155 (64%), Gaps = 1/155 (0%)
Frame = +1
Query: 271 EVNALEQRGYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFP 450
+ L ++GY++G +G+GSYA V A S + ++A KI D++K P DF+E+F P
Sbjct: 3 DATVLRKKGYIVGINLGKGSYAKVKSAY----SERLKFNVAVKIIDRKKTPTDFVERFLP 58
Query: 451 RELEILTKIENPHIIQVHSILQRGP-RVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFR 627
RE++IL + + II+ + I + R++I M GDLL+FIK G + E+ A+ FR
Sbjct: 59 REMDILATVNHGSIIKTYEIFETSDGRIYIIMELGVQGDLLEFIKCQGALHEDVARKMFR 118
Query: 628 QMASGLQYLHSKNIAHRDLKCENILLSRRFNVKLA 732
Q++S ++Y H +I HRDLKCEN+LL + FN+KL+
Sbjct: 119 QLSSAVKYCHDLDIVHRDLKCENLLLDKDFNIKLS 153
>AF362953-1|AAK98531.1| 358|Homo sapiens testis specific
serine/threonine kinase 2 protein.
Length = 358
Score = 135 bits (327), Expect = 1e-31
Identities = 64/155 (41%), Positives = 100/155 (64%), Gaps = 1/155 (0%)
Frame = +1
Query: 271 EVNALEQRGYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFP 450
+ L ++GY++G +G+GSYA V A S + ++A KI D++K P DF+E+F P
Sbjct: 3 DATVLRKKGYIVGINLGKGSYAKVKSAY----SERLKFNVAVKIIDRKKTPTDFVERFLP 58
Query: 451 RELEILTKIENPHIIQVHSILQRGP-RVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFR 627
RE++IL + + II+ + I + R++I M GDLL+FIK G + E+ A+ FR
Sbjct: 59 REMDILATVNHGSIIKTYEIFETSDGRIYIIMELGVQGDLLEFIKCQGALHEDVARKMFR 118
Query: 628 QMASGLQYLHSKNIAHRDLKCENILLSRRFNVKLA 732
Q++S ++Y H +I HRDLKCEN+LL + FN+KL+
Sbjct: 119 QLSSAVKYCHDLDIVHRDLKCENLLLDKDFNIKLS 153
>AB284523-1|BAF41974.1| 358|Homo sapiens testis-specific serine
kinase 2 protein.
Length = 358
Score = 135 bits (327), Expect = 1e-31
Identities = 64/155 (41%), Positives = 100/155 (64%), Gaps = 1/155 (0%)
Frame = +1
Query: 271 EVNALEQRGYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFP 450
+ L ++GY++G +G+GSYA V A S + ++A KI D++K P DF+E+F P
Sbjct: 3 DATVLRKKGYIVGINLGKGSYAKVKSAY----SERLKFNVAVKIIDRKKTPTDFVERFLP 58
Query: 451 RELEILTKIENPHIIQVHSILQRGP-RVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFR 627
RE++IL + + II+ + I + R++I M GDLL+FIK G + E+ A+ FR
Sbjct: 59 REMDILATVNHGSIIKTYEIFETSDGRIYIIMELGVQGDLLEFIKCQGALHEDVARKMFR 118
Query: 628 QMASGLQYLHSKNIAHRDLKCENILLSRRFNVKLA 732
Q++S ++Y H +I HRDLKCEN+LL + FN+KL+
Sbjct: 119 QLSSAVKYCHDLDIVHRDLKCENLLLDKDFNIKLS 153
>BC022515-1|AAH22515.1| 367|Homo sapiens testis-specific serine
kinase 1B protein.
Length = 367
Score = 135 bits (326), Expect = 2e-31
Identities = 66/151 (43%), Positives = 100/151 (66%), Gaps = 1/151 (0%)
Frame = +1
Query: 283 LEQRGYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELE 462
L++RGYL+G +G+GSYA V A S + ++A KI D++KAP DFLEKF PRE+E
Sbjct: 7 LKRRGYLLGINLGEGSYAKVKSAY----SERLKFNVAIKIIDRKKAPADFLEKFLPREIE 62
Query: 463 ILTKIENPHIIQVHSILQRGP-RVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMAS 639
IL + + II+ + I + +V+I M A GDLL+ IK G + E++A+ F Q++
Sbjct: 63 ILAMLNHCSIIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGALHEDEARKKFHQLSL 122
Query: 640 GLQYLHSKNIAHRDLKCENILLSRRFNVKLA 732
++Y H ++ HRDLKC+N+LL + FN+KL+
Sbjct: 123 AIKYCHDLDVVHRDLKCDNLLLDKDFNIKLS 153
>AY028964-1|AAK27734.1| 367|Homo sapiens testis-specific
serine/threonine kinase 1 protein.
Length = 367
Score = 135 bits (326), Expect = 2e-31
Identities = 66/151 (43%), Positives = 100/151 (66%), Gaps = 1/151 (0%)
Frame = +1
Query: 283 LEQRGYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELE 462
L++RGYL+G +G+GSYA V A S + ++A KI D++KAP DFLEKF PRE+E
Sbjct: 7 LKRRGYLLGINLGEGSYAKVKSAY----SERLKFNVAIKIIDRKKAPADFLEKFLPREIE 62
Query: 463 ILTKIENPHIIQVHSILQRGP-RVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMAS 639
IL + + II+ + I + +V+I M A GDLL+ IK G + E++A+ F Q++
Sbjct: 63 ILAMLNHCSIIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGALHEDEARKKFHQLSL 122
Query: 640 GLQYLHSKNIAHRDLKCENILLSRRFNVKLA 732
++Y H ++ HRDLKC+N+LL + FN+KL+
Sbjct: 123 AIKYCHDLDVVHRDLKCDNLLLDKDFNIKLS 153
>AB284522-1|BAF41973.1| 367|Homo sapiens testis-specific serine
kinase 1 protein.
Length = 367
Score = 135 bits (326), Expect = 2e-31
Identities = 66/151 (43%), Positives = 100/151 (66%), Gaps = 1/151 (0%)
Frame = +1
Query: 283 LEQRGYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELE 462
L++RGYL+G +G+GSYA V A S + ++A KI D++KAP DFLEKF PRE+E
Sbjct: 7 LKRRGYLLGINLGEGSYAKVKSAY----SERLKFNVAIKIIDRKKAPADFLEKFLPREIE 62
Query: 463 ILTKIENPHIIQVHSILQRGP-RVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMAS 639
IL + + II+ + I + +V+I M A GDLL+ IK G + E++A+ F Q++
Sbjct: 63 ILAMLNHCSIIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGALHEDEARKKFHQLSL 122
Query: 640 GLQYLHSKNIAHRDLKCENILLSRRFNVKLA 732
++Y H ++ HRDLKC+N+LL + FN+KL+
Sbjct: 123 AIKYCHDLDVVHRDLKCDNLLLDKDFNIKLS 153
>AY461663-1|AAS17971.1| 328|Homo sapiens testis-specific serine
kinase 4 protein.
Length = 328
Score = 128 bits (309), Expect = 2e-29
Identities = 60/150 (40%), Positives = 97/150 (64%)
Frame = +1
Query: 283 LEQRGYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELE 462
+++ GY +GK IG GSY +V+ A Y + +++ +A KI K+KA D+L KF PRE++
Sbjct: 20 MDEYGYEVGKAIGHGSYGSVYEAFY----TKQKVMVAVKIISKKKASDDYLNKFLPREIQ 75
Query: 463 ILTKIENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASG 642
++ + + ++I + ++ RV+I + A GD+L++I+R G E A WF Q+ G
Sbjct: 76 VMKVLRHKYLINFYRAIESTSRVYIILELAQGGDVLEWIQRYGACSEPLAGKWFSQLTLG 135
Query: 643 LQYLHSKNIAHRDLKCENILLSRRFNVKLA 732
+ YLHSK+I HRDLK EN+LL + NVK++
Sbjct: 136 IAYLHSKSIVHRDLKLENLLLDKWENVKIS 165
>BC035354-1|AAH35354.1| 268|Homo sapiens testis-specific serine
kinase 3 protein.
Length = 268
Score = 120 bits (289), Expect = 5e-27
Identities = 60/150 (40%), Positives = 94/150 (62%), Gaps = 1/150 (0%)
Frame = +1
Query: 283 LEQRGYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELE 462
L GY +GK IG+G+Y+ V A S + +A K+ DK P +F+++F PREL+
Sbjct: 5 LLSNGYQLGKTIGEGTYSKVKEAF----SKKHQRKVAIKVIDKMGGPEEFIQRFLPRELQ 60
Query: 463 ILTKIENPHIIQVHSILQRGP-RVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMAS 639
I+ +++ +IIQV+ +L+ ++ + M A+ GD+ D + G +PE++AK FRQM
Sbjct: 61 IVRTLDHKNIIQVYEMLESADGKICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVE 120
Query: 640 GLQYLHSKNIAHRDLKCENILLSRRFNVKL 729
++Y H +AHRDLKCEN LL + FN+KL
Sbjct: 121 AIRYCHGCGVAHRDLKCENALL-QGFNLKL 149
>AY048701-1|AAL02128.1| 268|Homo sapiens TSSK3 protein.
Length = 268
Score = 120 bits (289), Expect = 5e-27
Identities = 60/150 (40%), Positives = 94/150 (62%), Gaps = 1/150 (0%)
Frame = +1
Query: 283 LEQRGYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELE 462
L GY +GK IG+G+Y+ V A S + +A K+ DK P +F+++F PREL+
Sbjct: 5 LLSNGYQLGKTIGEGTYSKVKEAF----SKKHQRKVAIKVIDKMGGPEEFIQRFLPRELQ 60
Query: 463 ILTKIENPHIIQVHSILQRGP-RVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMAS 639
I+ +++ +IIQV+ +L+ ++ + M A+ GD+ D + G +PE++AK FRQM
Sbjct: 61 IVRTLDHKNIIQVYEMLESADGKICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVE 120
Query: 640 GLQYLHSKNIAHRDLKCENILLSRRFNVKL 729
++Y H +AHRDLKCEN LL + FN+KL
Sbjct: 121 AIRYCHGCGVAHRDLKCENALL-QGFNLKL 149
>AL109945-4|CAI22888.1| 268|Homo sapiens testis-specific serine
kinase 3 protein.
Length = 268
Score = 120 bits (289), Expect = 5e-27
Identities = 60/150 (40%), Positives = 94/150 (62%), Gaps = 1/150 (0%)
Frame = +1
Query: 283 LEQRGYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELE 462
L GY +GK IG+G+Y+ V A S + +A K+ DK P +F+++F PREL+
Sbjct: 5 LLSNGYQLGKTIGEGTYSKVKEAF----SKKHQRKVAIKVIDKMGGPEEFIQRFLPRELQ 60
Query: 463 ILTKIENPHIIQVHSILQRGP-RVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMAS 639
I+ +++ +IIQV+ +L+ ++ + M A+ GD+ D + G +PE++AK FRQM
Sbjct: 61 IVRTLDHKNIIQVYEMLESADGKICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVE 120
Query: 640 GLQYLHSKNIAHRDLKCENILLSRRFNVKL 729
++Y H +AHRDLKCEN LL + FN+KL
Sbjct: 121 AIRYCHGCGVAHRDLKCENALL-QGFNLKL 149
>AF296450-1|AAK97141.1| 268|Homo sapiens testis-specific
serine/threonine kinase 3 protein.
Length = 268
Score = 120 bits (289), Expect = 5e-27
Identities = 60/150 (40%), Positives = 94/150 (62%), Gaps = 1/150 (0%)
Frame = +1
Query: 283 LEQRGYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELE 462
L GY +GK IG+G+Y+ V A S + +A K+ DK P +F+++F PREL+
Sbjct: 5 LLSNGYQLGKTIGEGTYSKVKEAF----SKKHQRKVAIKVIDKMGGPEEFIQRFLPRELQ 60
Query: 463 ILTKIENPHIIQVHSILQRGP-RVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMAS 639
I+ +++ +IIQV+ +L+ ++ + M A+ GD+ D + G +PE++AK FRQM
Sbjct: 61 IVRTLDHKNIIQVYEMLESADGKICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVE 120
Query: 640 GLQYLHSKNIAHRDLKCENILLSRRFNVKL 729
++Y H +AHRDLKCEN LL + FN+KL
Sbjct: 121 AIRYCHGCGVAHRDLKCENALL-QGFNLKL 149
>BC014611-1|AAH14611.1| 273|Homo sapiens testis-specific serine
kinase 6 protein.
Length = 273
Score = 117 bits (282), Expect = 4e-26
Identities = 60/143 (41%), Positives = 90/143 (62%), Gaps = 1/143 (0%)
Frame = +1
Query: 283 LEQRGYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELE 462
L + GY +G+ IG+GSY+ V +A S + +A K+ D+ +AP DF+ KF PREL
Sbjct: 7 LSELGYKLGRTIGEGSYSKVKVAT----SKKYKGTVAIKVVDRRRAPPDFVNKFLPRELS 62
Query: 463 ILTKIENPHIIQVHSILQR-GPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMAS 639
IL + +PHI+ V ++ +++I M A DLL ++RNG +P QA+ F Q+A
Sbjct: 63 ILRGVRHPHIVHVFEFIEVCNGKLYIVMEAAAT-DLLQAVQRNGRIPGVQARDLFAQIAG 121
Query: 640 GLQYLHSKNIAHRDLKCENILLS 708
++YLH ++ HRDLKCEN+LLS
Sbjct: 122 AVRYLHDHHLVHRDLKCENVLLS 144
>AK172841-1|BAD18805.1| 406|Homo sapiens protein ( Homo sapiens
cDNA FLJ24002 fis, clone KAIA4350, highly similar to
Homo sapiens serine/threonine protein kinase SSTK
(SSTK). ).
Length = 406
Score = 117 bits (282), Expect = 4e-26
Identities = 60/143 (41%), Positives = 90/143 (62%), Gaps = 1/143 (0%)
Frame = +1
Query: 283 LEQRGYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELE 462
L + GY +G+ IG+GSY+ V +A S + +A K+ D+ +AP DF+ KF PREL
Sbjct: 7 LSELGYKLGRTIGEGSYSKVKVAT----SKKYKGTVAIKVVDRRRAPPDFVNKFLPRELS 62
Query: 463 ILTKIENPHIIQVHSILQR-GPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMAS 639
IL + +PHI+ V ++ +++I M A DLL ++RNG +P QA+ F Q+A
Sbjct: 63 ILRGVRHPHIVHVFEFIEVCNGKLYIVMEAAAT-DLLQAVQRNGRIPGVQARDLFAQIAG 121
Query: 640 GLQYLHSKNIAHRDLKCENILLS 708
++YLH ++ HRDLKCEN+LLS
Sbjct: 122 AVRYLHDHHLVHRDLKCENVLLS 144
>AF329483-1|AAK48827.1| 273|Homo sapiens serine/threonine protein
kinase SSTK protein.
Length = 273
Score = 117 bits (282), Expect = 4e-26
Identities = 60/143 (41%), Positives = 90/143 (62%), Gaps = 1/143 (0%)
Frame = +1
Query: 283 LEQRGYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELE 462
L + GY +G+ IG+GSY+ V +A S + +A K+ D+ +AP DF+ KF PREL
Sbjct: 7 LSELGYKLGRTIGEGSYSKVKVAT----SKKYKGTVAIKVVDRRRAPPDFVNKFLPRELS 62
Query: 463 ILTKIENPHIIQVHSILQR-GPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMAS 639
IL + +PHI+ V ++ +++I M A DLL ++RNG +P QA+ F Q+A
Sbjct: 63 ILRGVRHPHIVHVFEFIEVCNGKLYIVMEAAAT-DLLQAVQRNGRIPGVQARDLFAQIAG 121
Query: 640 GLQYLHSKNIAHRDLKCENILLS 708
++YLH ++ HRDLKCEN+LLS
Sbjct: 122 AVRYLHDHHLVHRDLKCENVLLS 144
>AK131042-1|BAC85482.1| 338|Homo sapiens protein ( Homo sapiens
cDNA FLJ29008 fis, clone TST06032. ).
Length = 338
Score = 117 bits (281), Expect = 5e-26
Identities = 60/160 (37%), Positives = 97/160 (60%), Gaps = 10/160 (6%)
Frame = +1
Query: 283 LEQRGYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELE 462
+++ GY +GK IG GSY +V+ A Y + +++ +A KI K+KA D+L KF PRE++
Sbjct: 20 MDEYGYEVGKAIGHGSYGSVYEAFY----TKQKVMVAVKIISKKKASDDYLNKFLPREIQ 75
Query: 463 ILTKIENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASG 642
++ + + ++I + ++ RV+I + A GD+L++I+R G E A WF Q+ G
Sbjct: 76 VMKVLRHKYLINFYRAIESTSRVYIILELAQGGDVLEWIRRYGACSEPLAGKWFSQLTLG 135
Query: 643 LQYLHSKNIAH----------RDLKCENILLSRRFNVKLA 732
+ YLHSK+I H RDLK EN+LL + NVK++
Sbjct: 136 IAYLHSKSIVHRLMPSLSAAGRDLKLENLLLDKWENVKIS 175
>BC084540-1|AAH84540.1| 724|Homo sapiens MAP/microtubule
affinity-regulating kinase 2 protein.
Length = 724
Score = 105 bits (253), Expect = 1e-22
Identities = 58/169 (34%), Positives = 98/169 (57%), Gaps = 3/169 (1%)
Frame = +1
Query: 235 SSMADRLSPRSSEVNALEQR---GYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIF 405
SS ++ + R+S +A EQ Y + K IG+G++A V LA + +A KI
Sbjct: 29 SSKSNMIRGRNSATSADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGK----EVAVKII 84
Query: 406 DKEKAPRDFLEKFFPRELEILTKIENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKR 585
DK + L+K F RE+ I+ + +P+I+++ +++ +++ M YA G++ D++
Sbjct: 85 DKTQLNSSSLQKLF-REVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVA 143
Query: 586 NGVVPENQAKLWFRQMASGLQYLHSKNIAHRDLKCENILLSRRFNVKLA 732
+G + E +A+ FRQ+ S +QY H K I HRDLK EN+LL N+K+A
Sbjct: 144 HGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIA 192
>BC008771-1|AAH08771.2| 778|Homo sapiens MARK2 protein protein.
Length = 778
Score = 105 bits (253), Expect = 1e-22
Identities = 58/169 (34%), Positives = 98/169 (57%), Gaps = 3/169 (1%)
Frame = +1
Query: 235 SSMADRLSPRSSEVNALEQR---GYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIF 405
SS ++ + R+S +A EQ Y + K IG+G++A V LA + +A KI
Sbjct: 19 SSKSNMIRGRNSATSADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGK----EVAVKII 74
Query: 406 DKEKAPRDFLEKFFPRELEILTKIENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKR 585
DK + L+K F RE+ I+ + +P+I+++ +++ +++ M YA G++ D++
Sbjct: 75 DKTQLNSSSLQKLF-REVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVA 133
Query: 586 NGVVPENQAKLWFRQMASGLQYLHSKNIAHRDLKCENILLSRRFNVKLA 732
+G + E +A+ FRQ+ S +QY H K I HRDLK EN+LL N+K+A
Sbjct: 134 HGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIA 182
>AB188493-1|BAD37141.1| 719|Homo sapiens serine/threonine kinase
protein.
Length = 719
Score = 105 bits (253), Expect = 1e-22
Identities = 58/169 (34%), Positives = 98/169 (57%), Gaps = 3/169 (1%)
Frame = +1
Query: 235 SSMADRLSPRSSEVNALEQR---GYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIF 405
SS ++ + R+S +A EQ Y + K IG+G++A V LA + +A KI
Sbjct: 29 SSKSNMIRGRNSATSADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGK----EVAVKII 84
Query: 406 DKEKAPRDFLEKFFPRELEILTKIENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKR 585
DK + L+K F RE+ I+ + +P+I+++ +++ +++ M YA G++ D++
Sbjct: 85 DKTQLNSSSLQKLF-REVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVA 143
Query: 586 NGVVPENQAKLWFRQMASGLQYLHSKNIAHRDLKCENILLSRRFNVKLA 732
+G + E +A+ FRQ+ S +QY H K I HRDLK EN+LL N+K+A
Sbjct: 144 HGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIA 192
>BC038504-1|AAH38504.1| 783|Homo sapiens SNF1-like kinase protein.
Length = 783
Score = 104 bits (249), Expect = 4e-22
Identities = 50/145 (34%), Positives = 89/145 (61%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y I + +G+G++A V LA + + +A KI DK + LEK + RE++++ +
Sbjct: 27 YDIERTLGKGNFAVVKLARH----RVTKTQVAIKIIDKTRLDSSNLEKIY-REVQLMKLL 81
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
+PHII+++ +++ ++I +A NG++ D++ NG + EN+A+ F Q+ S ++Y H
Sbjct: 82 NHPHIIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSAVEYCH 141
Query: 658 SKNIAHRDLKCENILLSRRFNVKLA 732
+I HRDLK EN+LL ++KLA
Sbjct: 142 DHHIVHRDLKTENLLLDGNMDIKLA 166
>AP001751-1|BAA95536.1| 786|Homo sapiens SNF1LK protein.
Length = 786
Score = 104 bits (249), Expect = 4e-22
Identities = 50/145 (34%), Positives = 89/145 (61%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y I + +G+G++A V LA + + +A KI DK + LEK + RE++++ +
Sbjct: 27 YDIERTLGKGNFAVVKLARH----RVTKTQVAIKIIDKTRLDSSNLEKIY-REVQLMKLL 81
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
+PHII+++ +++ ++I +A NG++ D++ NG + EN+A+ F Q+ S ++Y H
Sbjct: 82 NHPHIIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSAVEYCH 141
Query: 658 SKNIAHRDLKCENILLSRRFNVKLA 732
+I HRDLK EN+LL ++KLA
Sbjct: 142 DHHIVHRDLKTENLLLDGNMDIKLA 166
>AK131076-1|BAC85126.1| 764|Homo sapiens FLJ00263 protein protein.
Length = 764
Score = 104 bits (249), Expect = 4e-22
Identities = 50/145 (34%), Positives = 89/145 (61%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y I + +G+G++A V LA + + +A KI DK + LEK + RE++++ +
Sbjct: 8 YDIERTLGKGNFAVVKLARH----RVTKTQVAIKIIDKTRLDSSNLEKIY-REVQLMKLL 62
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
+PHII+++ +++ ++I +A NG++ D++ NG + EN+A+ F Q+ S ++Y H
Sbjct: 63 NHPHIIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSAVEYCH 122
Query: 658 SKNIAHRDLKCENILLSRRFNVKLA 732
+I HRDLK EN+LL ++KLA
Sbjct: 123 DHHIVHRDLKTENLLLDGNMDIKLA 147
>AB047786-1|BAD74070.1| 783|Homo sapiens serine/threonine protein
kinase protein.
Length = 783
Score = 104 bits (249), Expect = 4e-22
Identities = 50/145 (34%), Positives = 89/145 (61%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y I + +G+G++A V LA + + +A KI DK + LEK + RE++++ +
Sbjct: 27 YDIERTLGKGNFAVVKLARH----RVTKTQVAIKIIDKTRLDSSNLEKIY-REVQLMKLL 81
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
+PHII+++ +++ ++I +A NG++ D++ NG + EN+A+ F Q+ S ++Y H
Sbjct: 82 NHPHIIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSAVEYCH 141
Query: 658 SKNIAHRDLKCENILLSRRFNVKLA 732
+I HRDLK EN+LL ++KLA
Sbjct: 142 DHHIVHRDLKTENLLLDGNMDIKLA 166
>X97630-1|CAA66229.1| 745|Homo sapiens serine/threonine protein
kinase protein.
Length = 745
Score = 103 bits (246), Expect = 9e-22
Identities = 56/160 (35%), Positives = 93/160 (58%), Gaps = 3/160 (1%)
Frame = +1
Query: 262 RSSEVNALEQR---GYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDF 432
R+S +A EQ Y + K IG+G++A V LA + +A KI DK +
Sbjct: 5 RNSATSADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGK----EVAVKIIDKTQLNSSS 60
Query: 433 LEKFFPRELEILTKIENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQA 612
L+K F RE+ I+ + +P+I+++ +++ +++ M YA G++ D++ +G + E +A
Sbjct: 61 LQKLF-REVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEA 119
Query: 613 KLWFRQMASGLQYLHSKNIAHRDLKCENILLSRRFNVKLA 732
+ FRQ+ S +QY H K I HRDLK EN+LL N+K+A
Sbjct: 120 RAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIA 159
>BT007342-1|AAP36006.1| 755|Homo sapiens MAP/microtubule
affinity-regulating kinase 2 protein.
Length = 755
Score = 103 bits (246), Expect = 9e-22
Identities = 56/160 (35%), Positives = 93/160 (58%), Gaps = 3/160 (1%)
Frame = +1
Query: 262 RSSEVNALEQR---GYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDF 432
R+S +A EQ Y + K IG+G++A V LA + +A KI DK +
Sbjct: 5 RNSATSADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGK----EVAVKIIDKTQLNSSS 60
Query: 433 LEKFFPRELEILTKIENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQA 612
L+K F RE+ I+ + +P+I+++ +++ +++ M YA G++ D++ +G + E +A
Sbjct: 61 LQKLF-REVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEA 119
Query: 613 KLWFRQMASGLQYLHSKNIAHRDLKCENILLSRRFNVKLA 732
+ FRQ+ S +QY H K I HRDLK EN+LL N+K+A
Sbjct: 120 RAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIA 159
>AF387638-1|AAK82368.1| 691|Homo sapiens Ser/Thr protein kinase
PAR-1Balpha protein.
Length = 691
Score = 103 bits (246), Expect = 9e-22
Identities = 56/160 (35%), Positives = 93/160 (58%), Gaps = 3/160 (1%)
Frame = +1
Query: 262 RSSEVNALEQR---GYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDF 432
R+S +A EQ Y + K IG+G++A V LA + +A KI DK +
Sbjct: 5 RNSATSADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGK----EVAVKIIDKTQLNSSS 60
Query: 433 LEKFFPRELEILTKIENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQA 612
L+K F RE+ I+ + +P+I+++ +++ +++ M YA G++ D++ +G + E +A
Sbjct: 61 LQKLF-REVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEA 119
Query: 613 KLWFRQMASGLQYLHSKNIAHRDLKCENILLSRRFNVKLA 732
+ FRQ+ S +QY H K I HRDLK EN+LL N+K+A
Sbjct: 120 RAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIA 159
>BC117183-1|AAI17184.1| 926|Homo sapiens SNF1-like kinase 2
protein.
Length = 926
Score = 101 bits (243), Expect = 2e-21
Identities = 53/164 (32%), Positives = 94/164 (57%)
Frame = +1
Query: 241 MADRLSPRSSEVNALEQRGYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKA 420
MAD PR + + Y I +G+G++A V L + + +A KI DK +
Sbjct: 3 MAD--GPRHLQRGPVRVGFYDIEGTLGKGNFAVVKLGRH----RITKTEVAIKIIDKSQL 56
Query: 421 PRDFLEKFFPRELEILTKIENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVP 600
LEK + RE++I+ +++PHII+++ +++ +++ YA NG++ D++ +G +
Sbjct: 57 DAVNLEKIY-REVQIMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLN 115
Query: 601 ENQAKLWFRQMASGLQYLHSKNIAHRDLKCENILLSRRFNVKLA 732
E++A+ F Q+ S + Y H + I HRDLK EN+LL N+K+A
Sbjct: 116 ESEARRKFWQILSAVDYCHGRKIVHRDLKAENLLLDNNMNIKIA 159
>BC113459-1|AAI13460.1| 926|Homo sapiens SNF1-like kinase 2
protein.
Length = 926
Score = 101 bits (243), Expect = 2e-21
Identities = 53/164 (32%), Positives = 94/164 (57%)
Frame = +1
Query: 241 MADRLSPRSSEVNALEQRGYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKA 420
MAD PR + + Y I +G+G++A V L + + +A KI DK +
Sbjct: 3 MAD--GPRHLQRGPVRVGFYDIEGTLGKGNFAVVKLGRH----RITKTEVAIKIIDKSQL 56
Query: 421 PRDFLEKFFPRELEILTKIENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVP 600
LEK + RE++I+ +++PHII+++ +++ +++ YA NG++ D++ +G +
Sbjct: 57 DAVNLEKIY-REVQIMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLN 115
Query: 601 ENQAKLWFRQMASGLQYLHSKNIAHRDLKCENILLSRRFNVKLA 732
E++A+ F Q+ S + Y H + I HRDLK EN+LL N+K+A
Sbjct: 116 ESEARRKFWQILSAVDYCHGRKIVHRDLKAENLLLDNNMNIKIA 159
>AB084424-1|BAB91442.1| 346|Homo sapiens KIAA0781 protein protein.
Length = 346
Score = 101 bits (243), Expect = 2e-21
Identities = 53/164 (32%), Positives = 94/164 (57%)
Frame = +1
Query: 241 MADRLSPRSSEVNALEQRGYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKA 420
MAD PR + + Y I +G+G++A V L + + +A KI DK +
Sbjct: 1 MAD--GPRHLQRGPVRVGFYDIEGTLGKGNFAVVKLGRH----RITKTEVAIKIIDKSQL 54
Query: 421 PRDFLEKFFPRELEILTKIENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVP 600
LEK + RE++I+ +++PHII+++ +++ +++ YA NG++ D++ +G +
Sbjct: 55 DAVNLEKIY-REVQIMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLN 113
Query: 601 ENQAKLWFRQMASGLQYLHSKNIAHRDLKCENILLSRRFNVKLA 732
E++A+ F Q+ S + Y H + I HRDLK EN+LL N+K+A
Sbjct: 114 ESEARRKFWQILSAVDYCHGRKIVHRDLKAENLLLDNNMNIKIA 157
>AB018324-1|BAA34501.3| 950|Homo sapiens KIAA0781 protein protein.
Length = 950
Score = 101 bits (243), Expect = 2e-21
Identities = 53/164 (32%), Positives = 94/164 (57%)
Frame = +1
Query: 241 MADRLSPRSSEVNALEQRGYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKA 420
MAD PR + + Y I +G+G++A V L + + +A KI DK +
Sbjct: 27 MAD--GPRHLQRGPVRVGFYDIEGTLGKGNFAVVKLGRH----RITKTEVAIKIIDKSQL 80
Query: 421 PRDFLEKFFPRELEILTKIENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVP 600
LEK + RE++I+ +++PHII+++ +++ +++ YA NG++ D++ +G +
Sbjct: 81 DAVNLEKIY-REVQIMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLN 139
Query: 601 ENQAKLWFRQMASGLQYLHSKNIAHRDLKCENILLSRRFNVKLA 732
E++A+ F Q+ S + Y H + I HRDLK EN+LL N+K+A
Sbjct: 140 ESEARRKFWQILSAVDYCHGRKIVHRDLKAENLLLDNNMNIKIA 183
>U64205-1|AAC15093.1| 729|Homo sapiens Cdc25C associated protein
kinase C-TAK1 protein.
Length = 729
Score = 101 bits (242), Expect = 3e-21
Identities = 51/145 (35%), Positives = 86/145 (59%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y + K IG+G++A V LA + +A KI DK + L+K F RE+ I+ +
Sbjct: 56 YRLLKTIGKGNFAKVKLARHILTGR----EVAIKIIDKTQLNPTSLQKLF-REVRIMKIL 110
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
+P+I+++ +++ +++ M YA G++ D++ +G + E +A+ FRQ+ S +QY H
Sbjct: 111 NHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCH 170
Query: 658 SKNIAHRDLKCENILLSRRFNVKLA 732
K I HRDLK EN+LL N+K+A
Sbjct: 171 QKRIVHRDLKAENLLLDADMNIKIA 195
>BC024773-1|AAH24773.1| 729|Homo sapiens MAP/microtubule
affinity-regulating kinase 3 protein.
Length = 729
Score = 101 bits (242), Expect = 3e-21
Identities = 51/145 (35%), Positives = 86/145 (59%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y + K IG+G++A V LA + +A KI DK + L+K F RE+ I+ +
Sbjct: 56 YRLLKTIGKGNFAKVKLARHILTGR----EVAIKIIDKTQLNPTSLQKLF-REVRIMKIL 110
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
+P+I+++ +++ +++ M YA G++ D++ +G + E +A+ FRQ+ S +QY H
Sbjct: 111 NHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCH 170
Query: 658 SKNIAHRDLKCENILLSRRFNVKLA 732
K I HRDLK EN+LL N+K+A
Sbjct: 171 QKRIVHRDLKAENLLLDADMNIKIA 195
>AF387637-1|AAK82367.1| 744|Homo sapiens Ser/Thr protein kinase
PAR-1A protein.
Length = 744
Score = 101 bits (242), Expect = 3e-21
Identities = 51/145 (35%), Positives = 86/145 (59%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y + K IG+G++A V LA + +A KI DK + L+K F RE+ I+ +
Sbjct: 56 YRLLKTIGKGNFAKVKLARHILTGR----EVAIKIIDKTQLNPTSLQKLF-REVRIMKIL 110
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
+P+I+++ +++ +++ M YA G++ D++ +G + E +A+ FRQ+ S +QY H
Sbjct: 111 NHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCH 170
Query: 658 SKNIAHRDLKCENILLSRRFNVKLA 732
K I HRDLK EN+LL N+K+A
Sbjct: 171 QKRIVHRDLKAENLLLDADMNIKIA 195
>BC114478-1|AAI14479.1| 795|Homo sapiens MARK1 protein protein.
Length = 795
Score = 101 bits (241), Expect = 4e-21
Identities = 51/145 (35%), Positives = 86/145 (59%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y + K IG+G++A V LA + +A KI DK + L+K F RE+ I+ +
Sbjct: 60 YRLQKTIGKGNFAKVKLARHVLTGR----EVAVKIIDKTQLNPTSLQKLF-REVRIMKIL 114
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
+P+I+++ +++ +++ M YA G++ D++ +G + E +A+ FRQ+ S +QY H
Sbjct: 115 NHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCH 174
Query: 658 SKNIAHRDLKCENILLSRRFNVKLA 732
K I HRDLK EN+LL N+K+A
Sbjct: 175 QKYIVHRDLKAENLLLDGDMNIKIA 199
>BC113869-1|AAI13870.1| 795|Homo sapiens MARK1 protein protein.
Length = 795
Score = 101 bits (241), Expect = 4e-21
Identities = 51/145 (35%), Positives = 86/145 (59%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y + K IG+G++A V LA + +A KI DK + L+K F RE+ I+ +
Sbjct: 60 YRLQKTIGKGNFAKVKLARHVLTGR----EVAVKIIDKTQLNPTSLQKLF-REVRIMKIL 114
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
+P+I+++ +++ +++ M YA G++ D++ +G + E +A+ FRQ+ S +QY H
Sbjct: 115 NHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCH 174
Query: 658 SKNIAHRDLKCENILLSRRFNVKLA 732
K I HRDLK EN+LL N+K+A
Sbjct: 175 QKYIVHRDLKAENLLLDGDMNIKIA 199
>AL592406-3|CAH72463.1| 795|Homo sapiens MAP/microtubule
affinity-regulating kinase 1 protein.
Length = 795
Score = 101 bits (241), Expect = 4e-21
Identities = 51/145 (35%), Positives = 86/145 (59%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y + K IG+G++A V LA + +A KI DK + L+K F RE+ I+ +
Sbjct: 60 YRLQKTIGKGNFAKVKLARHVLTGR----EVAVKIIDKTQLNPTSLQKLF-REVRIMKIL 114
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
+P+I+++ +++ +++ M YA G++ D++ +G + E +A+ FRQ+ S +QY H
Sbjct: 115 NHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCH 174
Query: 658 SKNIAHRDLKCENILLSRRFNVKLA 732
K I HRDLK EN+LL N+K+A
Sbjct: 175 QKYIVHRDLKAENLLLDGDMNIKIA 199
>AF154845-1|AAF72103.1| 795|Homo sapiens MARK protein.
Length = 795
Score = 101 bits (241), Expect = 4e-21
Identities = 51/145 (35%), Positives = 86/145 (59%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y + K IG+G++A V LA + +A KI DK + L+K F RE+ I+ +
Sbjct: 60 YRLQKTIGKGNFAKVKLARHVLTGR----EVAVKIIDKTQLNPTSLQKLF-REVRIMKIL 114
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
+P+I+++ +++ +++ M YA G++ D++ +G + E +A+ FRQ+ S +QY H
Sbjct: 115 NHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCH 174
Query: 658 SKNIAHRDLKCENILLSRRFNVKLA 732
K I HRDLK EN+LL N+K+A
Sbjct: 175 QKYIVHRDLKAENLLLDGDMNIKIA 199
>AY120867-1|AAM55491.1| 752|Homo sapiens MAP/microtubule
affinity-regulating kinase-like 1 protein.
Length = 752
Score = 100 bits (240), Expect = 5e-21
Identities = 50/145 (34%), Positives = 86/145 (59%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y + + IG+G++A V LA + +A KI DK + L+K F RE+ I+ +
Sbjct: 59 YRLLRTIGKGNFAKVKLARHILTGR----EVAIKIIDKTQLNPSSLQKLF-REVRIMKGL 113
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
+P+I+++ +++ +++ M YA G++ D++ +G + E +A+ FRQ+ S + Y H
Sbjct: 114 NHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCH 173
Query: 658 SKNIAHRDLKCENILLSRRFNVKLA 732
KNI HRDLK EN+LL N+K+A
Sbjct: 174 QKNIVHRDLKAENLLLDAEANIKIA 198
>AY057448-1|AAL23683.1| 752|Homo sapiens MARK4 serine/threonine
protein kinase protein.
Length = 752
Score = 100 bits (240), Expect = 5e-21
Identities = 50/145 (34%), Positives = 86/145 (59%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y + + IG+G++A V LA + +A KI DK + L+K F RE+ I+ +
Sbjct: 59 YRLLRTIGKGNFAKVKLARHILTGR----EVAIKIIDKTQLNPSSLQKLF-REVRIMKGL 113
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
+P+I+++ +++ +++ M YA G++ D++ +G + E +A+ FRQ+ S + Y H
Sbjct: 114 NHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCH 173
Query: 658 SKNIAHRDLKCENILLSRRFNVKLA 732
KNI HRDLK EN+LL N+K+A
Sbjct: 174 QKNIVHRDLKAENLLLDAEANIKIA 198
>AK075272-1|BAC11510.1| 752|Homo sapiens protein ( Homo sapiens
cDNA FLJ90791 fis, clone THYRO1001593, moderately
similar to PUTATIVE SERINE/THREONINE-PROTEIN KINASE P78
(EC 2.7.1.-). ).
Length = 752
Score = 100 bits (240), Expect = 5e-21
Identities = 50/145 (34%), Positives = 86/145 (59%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y + + IG+G++A V LA + +A KI DK + L+K F RE+ I+ +
Sbjct: 59 YRLLRTIGKGNFAKVKLARHILTGR----EVAIKIIDKTQLNPSSLQKLF-REVRIMKGL 113
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
+P+I+++ +++ +++ M YA G++ D++ +G + E +A+ FRQ+ S + Y H
Sbjct: 114 NHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCH 173
Query: 658 SKNIAHRDLKCENILLSRRFNVKLA 732
KNI HRDLK EN+LL N+K+A
Sbjct: 174 QKNIVHRDLKAENLLLDAEANIKIA 198
>AB058763-1|BAB47489.1| 689|Homo sapiens KIAA1860 protein protein.
Length = 689
Score = 100 bits (240), Expect = 5e-21
Identities = 50/145 (34%), Positives = 86/145 (59%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y + + IG+G++A V LA + +A KI DK + L+K F RE+ I+ +
Sbjct: 60 YRLLRTIGKGNFAKVKLARHILTGR----EVAIKIIDKTQLNPSSLQKLF-REVRIMKGL 114
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
+P+I+++ +++ +++ M YA G++ D++ +G + E +A+ FRQ+ S + Y H
Sbjct: 115 NHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCH 174
Query: 658 SKNIAHRDLKCENILLSRRFNVKLA 732
KNI HRDLK EN+LL N+K+A
Sbjct: 175 QKNIVHRDLKAENLLLDAEANIKIA 199
>M80359-1|AAA59991.1| 713|Homo sapiens protein p78 protein.
Length = 713
Score = 100 bits (239), Expect = 6e-21
Identities = 51/145 (35%), Positives = 85/145 (58%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y + K IG+G++A V LA + +A KI DK + L+K F RE+ I+ +
Sbjct: 56 YRLLKTIGKGNFAKVKLARHILTGR----EVAIKIIDKTQLNPTSLQKLF-REVRIMKIL 110
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
+P+I+++ +++ +++ M YA G + D++ +G + E +A+ FRQ+ S +QY H
Sbjct: 111 NHPNIVKLFEVIETQKTLYLIMEYASGGKVFDYLVAHGRMKEKEARSKFRQIVSAVQYCH 170
Query: 658 SKNIAHRDLKCENILLSRRFNVKLA 732
K I HRDLK EN+LL N+K+A
Sbjct: 171 QKRIVHRDLKAENLLLDADMNIKIA 195
>AF465413-1|AAL69982.1| 753|Homo sapiens MAP/microtubule
affinity-regulating kinase 3 long isoform protein.
Length = 753
Score = 100 bits (239), Expect = 6e-21
Identities = 51/145 (35%), Positives = 85/145 (58%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y + K IG+G++A V LA + +A KI DK + L+K F RE+ I+ +
Sbjct: 56 YRLLKTIGKGNFAKVKLARHILTGR----EVAIKIIDKTQLNPTSLQKLF-REVRIMKIL 110
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
+P+I+++ +++ +++ M YA G + D++ +G + E +A+ FRQ+ S +QY H
Sbjct: 111 NHPNIVKLFEVIETEKTLYLIMEYASGGKVFDYLVAHGRMKEKEARSKFRQIVSAVQYCH 170
Query: 658 SKNIAHRDLKCENILLSRRFNVKLA 732
K I HRDLK EN+LL N+K+A
Sbjct: 171 QKRIVHRDLKAENLLLDADMNIKIA 195
>BC017306-1|AAH17306.1| 628|Homo sapiens NUAK family, SNF1-like
kinase, 2 protein.
Length = 628
Score = 99.5 bits (237), Expect = 1e-20
Identities = 50/139 (35%), Positives = 77/139 (55%)
Frame = +1
Query: 316 IGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKIENPHII 495
+G+G+Y V A G R+ +A K K+K + RE+EI++ + +PHII
Sbjct: 59 LGKGTYGKVKKARESSG----RL-VAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHPHII 113
Query: 496 QVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKNIAH 675
+H + + ++ I M YA GDL D+I + E +A+ +FRQ+ S + Y H + H
Sbjct: 114 AIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQNRVVH 173
Query: 676 RDLKCENILLSRRFNVKLA 732
RDLK ENILL N+K+A
Sbjct: 174 RDLKLENILLDANGNIKIA 192
>AK074830-1|BAC11234.1| 628|Homo sapiens protein ( Homo sapiens
cDNA FLJ90349 fis, clone NT2RP2003179, weakly similar to
PUTATIVE SERINE/THREONINE-PROTEIN KINASE EMK (EC
2.7.1.-). ).
Length = 628
Score = 99.5 bits (237), Expect = 1e-20
Identities = 50/139 (35%), Positives = 77/139 (55%)
Frame = +1
Query: 316 IGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKIENPHII 495
+G+G+Y V A G R+ +A K K+K + RE+EI++ + +PHII
Sbjct: 59 LGKGTYGKVKKARESSG----RL-VAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHPHII 113
Query: 496 QVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKNIAH 675
+H + + ++ I M YA GDL D+I + E +A+ +FRQ+ S + Y H + H
Sbjct: 114 AIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQNRVVH 173
Query: 676 RDLKCENILLSRRFNVKLA 732
RDLK ENILL N+K+A
Sbjct: 174 RDLKLENILLDANGNIKIA 192
>BC128510-1|AAI28511.1| 1203|Homo sapiens KIAA0999 protein protein.
Length = 1203
Score = 98.7 bits (235), Expect = 2e-20
Identities = 47/145 (32%), Positives = 87/145 (60%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y I + IG+G++A V A + + +A KI DK + + L+K F RE++I+ +
Sbjct: 8 YEIDRTIGKGNFAVVKRATHL----VTKAKVAIKIIDKTQLDEENLKKIF-REVQIMKML 62
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
+PHII+++ +++ +++ YA G++ D + +G + E +A+ F+Q+ + + + H
Sbjct: 63 CHPHIIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVTAVYFCH 122
Query: 658 SKNIAHRDLKCENILLSRRFNVKLA 732
+NI HRDLK EN+LL N+K+A
Sbjct: 123 CRNIVHRDLKAENLLLDANLNIKIA 147
>BC121188-1|AAI21189.1| 185|Homo sapiens KIAA0999 protein protein.
Length = 185
Score = 98.7 bits (235), Expect = 2e-20
Identities = 47/145 (32%), Positives = 87/145 (60%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y I + IG+G++A V A + + +A KI DK + + L+K F RE++I+ +
Sbjct: 30 YEIDRTIGKGNFAVVKRATHL----VTKAKVAIKIIDKTQLDEENLKKIF-REVQIMKML 84
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
+PHII+++ +++ +++ YA G++ D + +G + E +A+ F+Q+ + + + H
Sbjct: 85 CHPHIIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVTAVYFCH 144
Query: 658 SKNIAHRDLKCENILLSRRFNVKLA 732
+NI HRDLK EN+LL N+K+A
Sbjct: 145 CRNIVHRDLKAENLLLDANLNIKIA 169
>AB088047-1|BAC03375.1| 752|Homo sapiens microtubule
affinity-regulating kinase-like1 protein.
Length = 752
Score = 98.7 bits (235), Expect = 2e-20
Identities = 50/145 (34%), Positives = 85/145 (58%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y + + IG+G+ A V LA + +A KI DK + L+K F RE+ I+ +
Sbjct: 59 YRLLRTIGKGNSAKVKLARHILTGR----EVAIKIIDKTQLNPSSLQKLF-REVRIMKGL 113
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
+P+I+++ +++ +++ M YA G++ D++ +G + E +A+ FRQ+ S + Y H
Sbjct: 114 NHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCH 173
Query: 658 SKNIAHRDLKCENILLSRRFNVKLA 732
KNI HRDLK EN+LL N+K+A
Sbjct: 174 QKNIVHRDLKAENLLLDAEANIKIA 198
>AB049127-1|BAB39380.1| 688|Homo sapiens MAP/microtubule
affinity-regulating kinase like 1 protein.
Length = 688
Score = 98.7 bits (235), Expect = 2e-20
Identities = 50/145 (34%), Positives = 85/145 (58%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y + + IG+G+ A V LA + +A KI DK + L+K F RE+ I+ +
Sbjct: 59 YRLLRTIGKGNSAKVKLARHILTGR----EVAIKIIDKTQLNPSSLQKLF-REVRIMKGL 113
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
+P+I+++ +++ +++ M YA G++ D++ +G + E +A+ FRQ+ S + Y H
Sbjct: 114 NHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCH 173
Query: 658 SKNIAHRDLKCENILLSRRFNVKLA 732
KNI HRDLK EN+LL N+K+A
Sbjct: 174 QKNIVHRDLKAENLLLDAEANIKIA 198
>AB023216-1|BAA76843.2| 1371|Homo sapiens KIAA0999 protein protein.
Length = 1371
Score = 98.7 bits (235), Expect = 2e-20
Identities = 47/145 (32%), Positives = 87/145 (60%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y I + IG+G++A V A + + +A KI DK + + L+K F RE++I+ +
Sbjct: 116 YEIDRTIGKGNFAVVKRATHL----VTKAKVAIKIIDKTQLDEENLKKIF-REVQIMKML 170
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
+PHII+++ +++ +++ YA G++ D + +G + E +A+ F+Q+ + + + H
Sbjct: 171 CHPHIIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVTAVYFCH 230
Query: 658 SKNIAHRDLKCENILLSRRFNVKLA 732
+NI HRDLK EN+LL N+K+A
Sbjct: 231 CRNIVHRDLKAENLLLDANLNIKIA 255
>AY505124-1|AAS86442.1| 778|Homo sapiens protein kinase SAD-B
protein.
Length = 778
Score = 96.7 bits (230), Expect = 8e-20
Identities = 47/145 (32%), Positives = 83/145 (57%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y + K +G+G V L +C +A KI ++EK L K RE+ IL I
Sbjct: 34 YRLEKTLGKGQTGLVKLGVHCITGQK----VAIKIVNREKLSESVLMKV-EREIAILKLI 88
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
E+PH++++H + + +++ + + G+L D++ + G + +A+ +FRQ+ S L + H
Sbjct: 89 EHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCH 148
Query: 658 SKNIAHRDLKCENILLSRRFNVKLA 732
S +I HRDLK EN+LL + N+++A
Sbjct: 149 SYSICHRDLKPENLLLDEKNNIRIA 173
>AY458602-1|AAS10354.1| 778|Homo sapiens SAD1 kinase protein.
Length = 778
Score = 96.7 bits (230), Expect = 8e-20
Identities = 47/145 (32%), Positives = 83/145 (57%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y + K +G+G V L +C +A KI ++EK L K RE+ IL I
Sbjct: 34 YRLEKTLGKGQTGLVKLGVHCITGQK----VAIKIVNREKLSESVLMKV-EREIAILKLI 88
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
E+PH++++H + + +++ + + G+L D++ + G + +A+ +FRQ+ S L + H
Sbjct: 89 EHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCH 148
Query: 658 SKNIAHRDLKCENILLSRRFNVKLA 732
S +I HRDLK EN+LL + N+++A
Sbjct: 149 SYSICHRDLKPENLLLDEKNNIRIA 173
>AF479827-1|AAL87698.1| 778|Homo sapiens protein kinase-like
protein protein.
Length = 778
Score = 96.7 bits (230), Expect = 8e-20
Identities = 47/145 (32%), Positives = 83/145 (57%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y + K +G+G V L +C +A KI ++EK L K RE+ IL I
Sbjct: 34 YRLEKTLGKGQTGLVKLGVHCITGQK----VAIKIVNREKLSESVLMKV-EREIAILKLI 88
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
E+PH++++H + + +++ + + G+L D++ + G + +A+ +FRQ+ S L + H
Sbjct: 89 EHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCH 148
Query: 658 SKNIAHRDLKCENILLSRRFNVKLA 732
S +I HRDLK EN+LL + N+++A
Sbjct: 149 SYSICHRDLKPENLLLDEKNNIRIA 173
>AF479826-1|AAL87697.1| 794|Homo sapiens putative serine/threonine
protein kinase protein.
Length = 794
Score = 96.7 bits (230), Expect = 8e-20
Identities = 47/145 (32%), Positives = 83/145 (57%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y + K +G+G V L +C +A KI ++EK L K RE+ IL I
Sbjct: 50 YRLEKTLGKGQTGLVKLGVHCITGQK----VAIKIVNREKLSESVLMKV-EREIAILKLI 104
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
E+PH++++H + + +++ + + G+L D++ + G + +A+ +FRQ+ S L + H
Sbjct: 105 EHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCH 164
Query: 658 SKNIAHRDLKCENILLSRRFNVKLA 732
S +I HRDLK EN+LL + N+++A
Sbjct: 165 SYSICHRDLKPENLLLDEKNNIRIA 189
>AY505125-1|AAS86443.1| 696|Homo sapiens protein kinase SAD-A
protein.
Length = 696
Score = 96.3 bits (229), Expect = 1e-19
Identities = 47/145 (32%), Positives = 83/145 (57%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y + K +G+G V L +C +A KI ++EK L K RE+ IL I
Sbjct: 19 YRLEKTLGKGQTGLVKLGVHCVTCQK----VAIKIVNREKLSESVLMKV-EREIAILKLI 73
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
E+PH++++H + + +++ + + G+L D++ + G + +A+ +FRQ+ S L + H
Sbjct: 74 EHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCH 133
Query: 658 SKNIAHRDLKCENILLSRRFNVKLA 732
S +I HRDLK EN+LL + N+++A
Sbjct: 134 SHSICHRDLKPENLLLDEKNNIRIA 158
>AY166857-1|AAN87839.1| 668|Homo sapiens serine/threonine protein
kinase isoform protein.
Length = 668
Score = 96.3 bits (229), Expect = 1e-19
Identities = 47/145 (32%), Positives = 83/145 (57%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y + K +G+G V L +C +A KI ++EK L K RE+ IL I
Sbjct: 19 YRLEKTLGKGQTGLVKLGVHCVTCQK----VAIKIVNREKLSESVLMKV-EREIAILKLI 73
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
E+PH++++H + + +++ + + G+L D++ + G + +A+ +FRQ+ S L + H
Sbjct: 74 EHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCH 133
Query: 658 SKNIAHRDLKCENILLSRRFNVKLA 732
S +I HRDLK EN+LL + N+++A
Sbjct: 134 SHSICHRDLKPENLLLDEKNNIRIA 158
>AF533880-1|AAP97727.1| 674|Homo sapiens putative serine/threonine
protein kinase variant B3 protein.
Length = 674
Score = 96.3 bits (229), Expect = 1e-19
Identities = 47/145 (32%), Positives = 83/145 (57%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y + K +G+G V L +C +A KI ++EK L K RE+ IL I
Sbjct: 19 YRLEKTLGKGQTGLVKLGVHCVTCQK----VAIKIVNREKLSESVLMKV-EREIAILKLI 73
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
E+PH++++H + + +++ + + G+L D++ + G + +A+ +FRQ+ S L + H
Sbjct: 74 EHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCH 133
Query: 658 SKNIAHRDLKCENILLSRRFNVKLA 732
S +I HRDLK EN+LL + N+++A
Sbjct: 134 SHSICHRDLKPENLLLDEKNNIRIA 158
>AF533879-1|AAP97726.1| 736|Homo sapiens putative serine/threonine
protein kinase variant C protein.
Length = 736
Score = 96.3 bits (229), Expect = 1e-19
Identities = 47/145 (32%), Positives = 83/145 (57%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y + K +G+G V L +C +A KI ++EK L K RE+ IL I
Sbjct: 19 YRLEKTLGKGQTGLVKLGVHCVTCQK----VAIKIVNREKLSESVLMKV-EREIAILKLI 73
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
E+PH++++H + + +++ + + G+L D++ + G + +A+ +FRQ+ S L + H
Sbjct: 74 EHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCH 133
Query: 658 SKNIAHRDLKCENILLSRRFNVKLA 732
S +I HRDLK EN+LL + N+++A
Sbjct: 134 SHSICHRDLKPENLLLDEKNNIRIA 158
>AF533878-1|AAP97725.1| 674|Homo sapiens putative serine/threonine
protein kinase variant B2 protein.
Length = 674
Score = 96.3 bits (229), Expect = 1e-19
Identities = 47/145 (32%), Positives = 83/145 (57%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y + K +G+G V L +C +A KI ++EK L K RE+ IL I
Sbjct: 19 YRLEKTLGKGQTGLVKLGVHCVTCQK----VAIKIVNREKLSESVLMKV-EREIAILKLI 73
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
E+PH++++H + + +++ + + G+L D++ + G + +A+ +FRQ+ S L + H
Sbjct: 74 EHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCH 133
Query: 658 SKNIAHRDLKCENILLSRRFNVKLA 732
S +I HRDLK EN+LL + N+++A
Sbjct: 134 SHSICHRDLKPENLLLDEKNNIRIA 158
>AF533877-1|AAP97724.1| 674|Homo sapiens putative serine/threonine
protein kinase variant B1 protein.
Length = 674
Score = 96.3 bits (229), Expect = 1e-19
Identities = 47/145 (32%), Positives = 83/145 (57%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y + K +G+G V L +C +A KI ++EK L K RE+ IL I
Sbjct: 19 YRLEKTLGKGQTGLVKLGVHCVTCQK----VAIKIVNREKLSESVLMKV-EREIAILKLI 73
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
E+PH++++H + + +++ + + G+L D++ + G + +A+ +FRQ+ S L + H
Sbjct: 74 EHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCH 133
Query: 658 SKNIAHRDLKCENILLSRRFNVKLA 732
S +I HRDLK EN+LL + N+++A
Sbjct: 134 SHSICHRDLKPENLLLDEKNNIRIA 158
>AF533876-1|AAP97723.1| 668|Homo sapiens putative serine/threonine
protein kinase variant A protein.
Length = 668
Score = 96.3 bits (229), Expect = 1e-19
Identities = 47/145 (32%), Positives = 83/145 (57%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y + K +G+G V L +C +A KI ++EK L K RE+ IL I
Sbjct: 19 YRLEKTLGKGQTGLVKLGVHCVTCQK----VAIKIVNREKLSESVLMKV-EREIAILKLI 73
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
E+PH++++H + + +++ + + G+L D++ + G + +A+ +FRQ+ S L + H
Sbjct: 74 EHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCH 133
Query: 658 SKNIAHRDLKCENILLSRRFNVKLA 732
S +I HRDLK EN+LL + N+++A
Sbjct: 134 SHSICHRDLKPENLLLDEKNNIRIA 158
>BC056423-1|AAH56423.1| 214|Homo sapiens ULK3 protein protein.
Length = 214
Score = 94.7 bits (225), Expect = 3e-19
Identities = 49/138 (35%), Positives = 80/138 (57%)
Frame = +1
Query: 295 GYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTK 474
G+++ +++G G+YATV+ A R +A K K+ + +E E+EIL
Sbjct: 13 GFILTERLGSGTYATVYKAY---AKKDTREVVAIKCVAKKSLNKASVENLLT-EIEILKG 68
Query: 475 IENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYL 654
I +PHI+Q+ +++ M + GDL FI ++PE A+++ +Q+AS LQ+L
Sbjct: 69 IRHPHIVQLKDFQWDSDNIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQQLASALQFL 128
Query: 655 HSKNIAHRDLKCENILLS 708
H +NI+H DLK +NILLS
Sbjct: 129 HERNISHLDLKPQNILLS 146
>BC036117-1|AAH36117.1| 214|Homo sapiens ULK3 protein protein.
Length = 214
Score = 94.7 bits (225), Expect = 3e-19
Identities = 49/138 (35%), Positives = 80/138 (57%)
Frame = +1
Query: 295 GYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTK 474
G+++ +++G G+YATV+ A R +A K K+ + +E E+EIL
Sbjct: 13 GFILTERLGSGTYATVYKAY---AKKDTREVVAIKCVAKKSLNKASVENLLT-EIEILKG 68
Query: 475 IENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYL 654
I +PHI+Q+ +++ M + GDL FI ++PE A+++ +Q+AS LQ+L
Sbjct: 69 IRHPHIVQLKDFQWDSDNIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQQLASALQFL 128
Query: 655 HSKNIAHRDLKCENILLS 708
H +NI+H DLK +NILLS
Sbjct: 129 HERNISHLDLKPQNILLS 146
>AB011109-1|BAA25463.2| 698|Homo sapiens KIAA0537 protein protein.
Length = 698
Score = 93.1 bits (221), Expect = 9e-19
Identities = 47/145 (32%), Positives = 80/145 (55%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y + + +G+G+Y V A + S + + + DK K +D + RE+EI++ +
Sbjct: 92 YELQETLGKGTYGKVKRAT--ERFSGRVVAIKSIRKDKIKDEQDMVH--IRREIEIMSSL 147
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
+PHII ++ + + ++ I M YA G+L D+I + E + + +FRQ+ S + Y H
Sbjct: 148 NHPHIISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCH 207
Query: 658 SKNIAHRDLKCENILLSRRFNVKLA 732
+ HRDLK ENILL N+K+A
Sbjct: 208 KNGVVHRDLKLENILLDDNCNIKIA 232
>AK131534-1|BAD18671.1| 766|Homo sapiens protein ( Homo sapiens
cDNA FLJ16763 fis, clone BRAMY3018357, weakly similar
to SNF1-related protein kinase KIN10 (EC 2.7.1.-). ).
Length = 766
Score = 91.1 bits (216), Expect = 4e-18
Identities = 40/115 (34%), Positives = 72/115 (62%)
Frame = +1
Query: 388 LACKIFDKEKAPRDFLEKFFPRELEILTKIENPHIIQVHSILQRGPRVFIFMRYADNGDL 567
+A KI ++EK L K RE+ IL IE+PH++++H + + +++ + + G+L
Sbjct: 91 VAIKIVNREKLSESVLMKV-EREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGEL 149
Query: 568 LDFIKRNGVVPENQAKLWFRQMASGLQYLHSKNIAHRDLKCENILLSRRFNVKLA 732
D++ + G + +A+ +FRQ+ S L + HS +I HRDLK EN+LL + N+++A
Sbjct: 150 FDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIRIA 204
>BC037303-1|AAH37303.1| 550|Homo sapiens PRKAA1 protein protein.
Length = 550
Score = 90.6 bits (215), Expect = 5e-18
Identities = 45/145 (31%), Positives = 83/145 (57%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y++G +G G++ V + ++ + + K +A KI +++K + RE++ L
Sbjct: 18 YILGDTLGVGTFGKVKVGKH-ELTGHK---VAVKILNRQKIRSLDVVGKIRREIQNLKLF 73
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
+PHII+++ ++ +F+ M Y G+L D+I +NG + E +++ F+Q+ SG+ Y H
Sbjct: 74 RHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCH 133
Query: 658 SKNIAHRDLKCENILLSRRFNVKLA 732
+ HRDLK EN+LL N K+A
Sbjct: 134 RHMVVHRDLKPENVLLDAHMNAKIA 158
>BC012622-1|AAH12622.1| 207|Homo sapiens PRKAA1 protein protein.
Length = 207
Score = 90.6 bits (215), Expect = 5e-18
Identities = 45/145 (31%), Positives = 83/145 (57%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y++G +G G++ V + ++ + + K +A KI +++K + RE++ L
Sbjct: 18 YILGDTLGVGTFGKVKVGKH-ELTGHK---VAVKILNRQKIRSLDVVGKIRREIQNLKLF 73
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
+PHII+++ ++ +F+ M Y G+L D+I +NG + E +++ F+Q+ SG+ Y H
Sbjct: 74 RHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCH 133
Query: 658 SKNIAHRDLKCENILLSRRFNVKLA 732
+ HRDLK EN+LL N K+A
Sbjct: 134 RHMVVHRDLKPENVLLDAHMNAKIA 158
>AB022017-1|BAA36547.1| 550|Homo sapiens AMP-activated protein
kinase alpha-1 protein.
Length = 550
Score = 90.6 bits (215), Expect = 5e-18
Identities = 45/145 (31%), Positives = 83/145 (57%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y++G +G G++ V + ++ + + K +A KI +++K + RE++ L
Sbjct: 18 YILGDTLGVGTFGKVKVGKH-ELTGHK---VAVKILNRQKIRSLDVVGKIRREIQNLKLF 73
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
+PHII+++ ++ +F+ M Y G+L D+I +NG + E +++ F+Q+ SG+ Y H
Sbjct: 74 RHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCH 133
Query: 658 SKNIAHRDLKCENILLSRRFNVKLA 732
+ HRDLK EN+LL N K+A
Sbjct: 134 RHMVVHRDLKPENVLLDAHMNAKIA 158
>Y15056-1|CAA75341.1| 556|Homo sapiens PkB kinase protein.
Length = 556
Score = 89.4 bits (212), Expect = 1e-17
Identities = 44/144 (30%), Positives = 83/144 (57%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
+ GK +G+GS++TV LA S A KI +K ++ + RE ++++++
Sbjct: 82 FKFGKILGEGSFSTVVLARELATSR----EYAIKILEKRHIIKENKVPYVTRERDVMSRL 137
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
++P ++++ Q +++ + YA NG+LL +I++ G E + + ++ S L+YLH
Sbjct: 138 DHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLH 197
Query: 658 SKNIAHRDLKCENILLSRRFNVKL 729
K I HRDLK ENILL+ ++++
Sbjct: 198 GKGIIHRDLKPENILLNEDMHIQI 221
>CR536517-1|CAG38755.1| 556|Homo sapiens PDPK1 protein.
Length = 556
Score = 89.4 bits (212), Expect = 1e-17
Identities = 44/144 (30%), Positives = 83/144 (57%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
+ GK +G+GS++TV LA S A KI +K ++ + RE ++++++
Sbjct: 82 FKFGKILGEGSFSTVVLARELATSR----EYAIKILEKRHIIKENKVPYVTRERDVMSRL 137
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
++P ++++ Q +++ + YA NG+LL +I++ G E + + ++ S L+YLH
Sbjct: 138 DHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLH 197
Query: 658 SKNIAHRDLKCENILLSRRFNVKL 729
K I HRDLK ENILL+ ++++
Sbjct: 198 GKGIIHRDLKPENILLNEDMHIQI 221
>BC012103-1|AAH12103.1| 556|Homo sapiens 3-phosphoinositide
dependent protein kinase-1 protein.
Length = 556
Score = 89.4 bits (212), Expect = 1e-17
Identities = 44/144 (30%), Positives = 83/144 (57%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
+ GK +G+GS++TV LA S A KI +K ++ + RE ++++++
Sbjct: 82 FKFGKILGEGSFSTVVLARELATSR----EYAIKILEKRHIIKENKVPYVTRERDVMSRL 137
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
++P ++++ Q +++ + YA NG+LL +I++ G E + + ++ S L+YLH
Sbjct: 138 DHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLH 197
Query: 658 SKNIAHRDLKCENILLSRRFNVKL 729
K I HRDLK ENILL+ ++++
Sbjct: 198 GKGIIHRDLKPENILLNEDMHIQI 221
>AF017995-1|AAC51825.1| 556|Homo sapiens 3-phosphoinositide
dependent protein kinase-1 protein.
Length = 556
Score = 89.4 bits (212), Expect = 1e-17
Identities = 44/144 (30%), Positives = 83/144 (57%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
+ GK +G+GS++TV LA S A KI +K ++ + RE ++++++
Sbjct: 82 FKFGKILGEGSFSTVVLARELATSR----EYAIKILEKRHIIKENKVPYVTRERDVMSRL 137
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
++P ++++ Q +++ + YA NG+LL +I++ G E + + ++ S L+YLH
Sbjct: 138 DHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLH 197
Query: 658 SKNIAHRDLKCENILLSRRFNVKL 729
K I HRDLK ENILL+ ++++
Sbjct: 198 GKGIIHRDLKPENILLNEDMHIQI 221
>AC005591-1|AAC33797.1| 367|Homo sapiens PkB-like protein.
Length = 367
Score = 89.4 bits (212), Expect = 1e-17
Identities = 44/144 (30%), Positives = 83/144 (57%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
+ GK +G+GS++TV LA S A KI +K ++ + RE ++++++
Sbjct: 74 FKFGKILGEGSFSTVVLARELATSR----EYAIKILEKRHIIKENKVPYVTRERDVMSRL 129
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
++P ++++ Q +++ + YA NG+LL +I++ G E + + ++ S L+YLH
Sbjct: 130 DHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLH 189
Query: 658 SKNIAHRDLKCENILLSRRFNVKL 729
K I HRDLK ENILL+ ++++
Sbjct: 190 GKGIIHRDLKPENILLNEDMHIQI 213
>AB209835-1|BAD93072.1| 492|Homo sapiens 3-phosphoinositide
dependent protein kinase-1 variant protein.
Length = 492
Score = 89.4 bits (212), Expect = 1e-17
Identities = 44/144 (30%), Positives = 83/144 (57%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
+ GK +G+GS++TV LA S A KI +K ++ + RE ++++++
Sbjct: 120 FKFGKILGEGSFSTVVLARELATSR----EYAIKILEKRHIIKENKVPYVTRERDVMSRL 175
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
++P ++++ Q +++ + YA NG+LL +I++ G E + + ++ S L+YLH
Sbjct: 176 DHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLH 235
Query: 658 SKNIAHRDLKCENILLSRRFNVKL 729
K I HRDLK ENILL+ ++++
Sbjct: 236 GKGIIHRDLKPENILLNEDMHIQI 259
>EF056019-1|ABK30810.1| 552|Homo sapiens AMP-activated alpha 2
subunit protein.
Length = 552
Score = 88.2 bits (209), Expect = 3e-17
Identities = 45/145 (31%), Positives = 79/145 (54%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y++G +G G++ V++ E+ +A KI +++K + RE++ L
Sbjct: 16 YVLGDTLGVGTFGKVNIGEH----QLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLF 71
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
+PHII+++ ++ F+ M Y G+L D+I ++G V E +A+ F+Q+ S + Y H
Sbjct: 72 RHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCH 131
Query: 658 SKNIAHRDLKCENILLSRRFNVKLA 732
+ HRDLK EN+LL N K+A
Sbjct: 132 RHMVVHRDLKPENVLLDAHMNAKIA 156
>AJ785968-1|CAH05056.1| 396|Homo sapiens PDPK2 protein protein.
Length = 396
Score = 88.2 bits (209), Expect = 3e-17
Identities = 44/144 (30%), Positives = 82/144 (56%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
+ GK +G+GS++TV LA S A KI +K ++ + RE ++++++
Sbjct: 55 FKFGKILGEGSFSTVVLARELATSR----EYAIKILEKRHIIKENKVPYVTRERDVMSRL 110
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
++P ++++ Q +++ + YA NG+LL +I++ G E + + ++ S L+YLH
Sbjct: 111 DHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLH 170
Query: 658 SKNIAHRDLKCENILLSRRFNVKL 729
K I HRDLK ENILL+ +++
Sbjct: 171 GKGIIHRDLKPENILLNEDMYIQI 194
>AC005581-1|AAC33487.1| 462|Homo sapiens R31237_1, partial CDS
protein.
Length = 462
Score = 63.3 bits (147), Expect(2) = 4e-17
Identities = 26/58 (44%), Positives = 39/58 (67%)
Frame = +1
Query: 559 GDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKNIAHRDLKCENILLSRRFNVKLA 732
G++ D++ +G + E +A+ FRQ+ S + Y H KNI HRDLK EN+LL N+K+A
Sbjct: 171 GEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIA 228
Score = 44.8 bits (101), Expect(2) = 4e-17
Identities = 25/89 (28%), Positives = 49/89 (55%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y + + IG+G++A V LA + +A KI DK + L+K F RE+ I+ +
Sbjct: 59 YRLLRTIGKGNFAKVKLARHILTGR----EVAIKIIDKTQLNPSSLQKLF-REVRIMKGL 113
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGD 564
+P+I+++ +++ +++ M YA G+
Sbjct: 114 NHPNIVKLFEVIETEKTLYLVMEYASAGE 142
>U06454-1|AAA64745.1| 552|Homo sapiens AMP-activated protein kinase
protein.
Length = 552
Score = 87.4 bits (207), Expect = 5e-17
Identities = 45/145 (31%), Positives = 78/145 (53%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y++G +G G++ V + E+ +A KI +++K + RE++ L
Sbjct: 16 YVLGDTLGVGTFGKVKIGEH----QLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLF 71
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
+PHII+++ ++ F+ M Y G+L D+I ++G V E +A+ F+Q+ S + Y H
Sbjct: 72 RHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCH 131
Query: 658 SKNIAHRDLKCENILLSRRFNVKLA 732
+ HRDLK EN+LL N K+A
Sbjct: 132 RHMVVHRDLKPENVLLDAHMNAKIA 156
>BC069823-1|AAH69823.1| 552|Homo sapiens AMP-activated protein
kinase alpha 2 catalytic subunit protein.
Length = 552
Score = 87.4 bits (207), Expect = 5e-17
Identities = 45/145 (31%), Positives = 78/145 (53%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y++G +G G++ V + E+ +A KI +++K + RE++ L
Sbjct: 16 YVLGDTLGVGTFGKVKIGEH----QLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLF 71
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
+PHII+++ ++ F+ M Y G+L D+I ++G V E +A+ F+Q+ S + Y H
Sbjct: 72 RHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCH 131
Query: 658 SKNIAHRDLKCENILLSRRFNVKLA 732
+ HRDLK EN+LL N K+A
Sbjct: 132 RHMVVHRDLKPENVLLDAHMNAKIA 156
>BC069740-1|AAH69740.1| 552|Homo sapiens AMP-activated protein
kinase alpha 2 catalytic subunit protein.
Length = 552
Score = 87.4 bits (207), Expect = 5e-17
Identities = 45/145 (31%), Positives = 78/145 (53%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y++G +G G++ V + E+ +A KI +++K + RE++ L
Sbjct: 16 YVLGDTLGVGTFGKVKIGEH----QLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLF 71
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
+PHII+++ ++ F+ M Y G+L D+I ++G V E +A+ F+Q+ S + Y H
Sbjct: 72 RHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCH 131
Query: 658 SKNIAHRDLKCENILLSRRFNVKLA 732
+ HRDLK EN+LL N K+A
Sbjct: 132 RHMVVHRDLKPENVLLDAHMNAKIA 156
>BC069680-1|AAH69680.1| 552|Homo sapiens protein kinase,
AMP-activated, alpha 2 catalytic subunit protein.
Length = 552
Score = 87.4 bits (207), Expect = 5e-17
Identities = 45/145 (31%), Positives = 78/145 (53%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y++G +G G++ V + E+ +A KI +++K + RE++ L
Sbjct: 16 YVLGDTLGVGTFGKVKIGEH----QLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLF 71
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
+PHII+++ ++ F+ M Y G+L D+I ++G V E +A+ F+Q+ S + Y H
Sbjct: 72 RHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCH 131
Query: 658 SKNIAHRDLKCENILLSRRFNVKLA 732
+ HRDLK EN+LL N K+A
Sbjct: 132 RHMVVHRDLKPENVLLDAHMNAKIA 156
>AY714054-1|AAU04399.1| 306|Homo sapiens aurora-C protein.
Length = 306
Score = 87.4 bits (207), Expect = 5e-17
Identities = 45/158 (28%), Positives = 84/158 (53%)
Frame = +1
Query: 259 PRSSEVNALEQRGYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLE 438
P S + L + IG+ +G+G + V+LA + +A K+ K + ++ LE
Sbjct: 27 PSSPAMRRLTVDDFEIGRPLGKGKFGNVYLARLKES----HFIVALKVLFKSQIEKEGLE 82
Query: 439 KFFPRELEILTKIENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKL 618
RE+EI +++P+I+++++ RV++ + YA G+L ++++ + E +
Sbjct: 83 HQLRREIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTAT 142
Query: 619 WFRQMASGLQYLHSKNIAHRDLKCENILLSRRFNVKLA 732
++A L Y H K + HRD+K EN+LL R VK+A
Sbjct: 143 IIEELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIA 180
>AY661554-1|AAT64422.1| 290|Homo sapiens aurora/Ipl1-related kinase
3 transcript variant 1 protein.
Length = 290
Score = 87.4 bits (207), Expect = 5e-17
Identities = 45/158 (28%), Positives = 84/158 (53%)
Frame = +1
Query: 259 PRSSEVNALEQRGYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLE 438
P S + L + IG+ +G+G + V+LA + +A K+ K + ++ LE
Sbjct: 11 PSSPAMRRLTVDDFEIGRPLGKGKFGNVYLARLKES----HFIVALKVLFKSQIEKEGLE 66
Query: 439 KFFPRELEILTKIENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKL 618
RE+EI +++P+I+++++ RV++ + YA G+L ++++ + E +
Sbjct: 67 HQLRREIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTAT 126
Query: 619 WFRQMASGLQYLHSKNIAHRDLKCENILLSRRFNVKLA 732
++A L Y H K + HRD+K EN+LL R VK+A
Sbjct: 127 IIEELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIA 164
>AL035705-2|CAC17574.2| 552|Homo sapiens protein kinase,
AMP-activated, alpha 2 catalytic subunit protein.
Length = 552
Score = 87.4 bits (207), Expect = 5e-17
Identities = 45/145 (31%), Positives = 78/145 (53%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y++G +G G++ V + E+ +A KI +++K + RE++ L
Sbjct: 16 YVLGDTLGVGTFGKVKIGEH----QLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLF 71
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
+PHII+++ ++ F+ M Y G+L D+I ++G V E +A+ F+Q+ S + Y H
Sbjct: 72 RHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCH 131
Query: 658 SKNIAHRDLKCENILLSRRFNVKLA 732
+ HRDLK EN+LL N K+A
Sbjct: 132 RHMVVHRDLKPENVLLDAHMNAKIA 156
>AB058714-1|BAB47440.1| 715|Homo sapiens KIAA1811 protein protein.
Length = 715
Score = 87.4 bits (207), Expect = 5e-17
Identities = 38/111 (34%), Positives = 69/111 (62%)
Frame = +1
Query: 400 IFDKEKAPRDFLEKFFPRELEILTKIENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFI 579
I ++EK L K RE+ IL IE+PH++++H + + +++ + + G+L D++
Sbjct: 1 IVNREKLSESVLMKV-EREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYL 59
Query: 580 KRNGVVPENQAKLWFRQMASGLQYLHSKNIAHRDLKCENILLSRRFNVKLA 732
+ G + +A+ +FRQ+ S L + HS +I HRDLK EN+LL + N+++A
Sbjct: 60 VKKGRLTPKEARKFFRQIVSALDFCHSYSICHRDLKPENLLLDEKNNIRIA 110
>AB017332-1|BAA76292.1| 309|Homo sapiens Aurora/Ipl1-related kinase
3 protein.
Length = 309
Score = 87.4 bits (207), Expect = 5e-17
Identities = 45/158 (28%), Positives = 84/158 (53%)
Frame = +1
Query: 259 PRSSEVNALEQRGYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLE 438
P S + L + IG+ +G+G + V+LA + +A K+ K + ++ LE
Sbjct: 30 PSSPAMRRLTVDDFEIGRPLGKGKFGNVYLARLKES----HFIVALKVLFKSQIEKEGLE 85
Query: 439 KFFPRELEILTKIENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKL 618
RE+EI +++P+I+++++ RV++ + YA G+L ++++ + E +
Sbjct: 86 HQLRREIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTAT 145
Query: 619 WFRQMASGLQYLHSKNIAHRDLKCENILLSRRFNVKLA 732
++A L Y H K + HRD+K EN+LL R VK+A
Sbjct: 146 IIEELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIA 183
>AK222581-1|BAD96301.1| 556|Homo sapiens 3-phosphoinositide
dependent protein kinase-1 variant protein.
Length = 556
Score = 87.0 bits (206), Expect = 6e-17
Identities = 43/144 (29%), Positives = 82/144 (56%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
+ GK +G+GS++TV LA S A KI +K ++ + RE ++++++
Sbjct: 82 FKFGKILGEGSFSTVVLARELATSR----EYAIKILEKRHIIKENKVPYVTRERDVMSRL 137
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
++P ++++ Q +++ + YA NG+LL +I++ G E + + ++ S +YLH
Sbjct: 138 DHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSASEYLH 197
Query: 658 SKNIAHRDLKCENILLSRRFNVKL 729
K I HRDLK ENILL+ ++++
Sbjct: 198 GKGIIHRDLKPENILLNEDMHIQI 221
>BC063885-1|AAH63885.1| 708|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 5 protein.
Length = 708
Score = 86.6 bits (205), Expect = 8e-17
Identities = 52/140 (37%), Positives = 81/140 (57%), Gaps = 2/140 (1%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y + K IGQG++ +LA+ G S + H K + EK P E +E+ +L K+
Sbjct: 4 YDVIKAIGQGAFGKAYLAK---GKSDSK-HCVIKEINFEKMPIQEKEAS-KKEVILLEKM 58
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRN-GVV-PENQAKLWFRQMASGLQY 651
++P+I+ + Q R+FI M Y D GDL+ I R GV+ E+Q WF Q++ GL++
Sbjct: 59 KHPNIVAFFNSFQENGRLFIVMEYCDGGDLMKRINRQRGVLFSEDQILGWFVQISLGLKH 118
Query: 652 LHSKNIAHRDLKCENILLSR 711
+H + I HRD+K +NI LS+
Sbjct: 119 IHDRKILHRDIKAQNIFLSK 138
>AL139082-5|CAI12892.2| 708|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 5 protein.
Length = 708
Score = 86.6 bits (205), Expect = 8e-17
Identities = 52/140 (37%), Positives = 81/140 (57%), Gaps = 2/140 (1%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y + K IGQG++ +LA+ G S + H K + EK P E +E+ +L K+
Sbjct: 4 YDVIKAIGQGAFGKAYLAK---GKSDSK-HCVIKEINFEKMPIQEKEAS-KKEVILLEKM 58
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRN-GVV-PENQAKLWFRQMASGLQY 651
++P+I+ + Q R+FI M Y D GDL+ I R GV+ E+Q WF Q++ GL++
Sbjct: 59 KHPNIVAFFNSFQENGRLFIVMEYCDGGDLMKRINRQRGVLFSEDQILGWFVQISLGLKH 118
Query: 652 LHSKNIAHRDLKCENILLSR 711
+H + I HRD+K +NI LS+
Sbjct: 119 IHDRKILHRDIKAQNIFLSK 138
>AF054621-1|AAC25955.1| 309|Homo sapiens serine/threonine kinase
AIE2 protein.
Length = 309
Score = 86.6 bits (205), Expect = 8e-17
Identities = 45/158 (28%), Positives = 84/158 (53%)
Frame = +1
Query: 259 PRSSEVNALEQRGYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLE 438
P S + L + IG+ +G+G + V+LA + +A K+ K + ++ LE
Sbjct: 30 PSSPAMRRLTVDDFEIGRPLGKGKFGNVYLARLKES----HFIVALKVLFKSQIEKEGLE 85
Query: 439 KFFPRELEILTKIENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKL 618
RE+EI +++P+I+++++ RV++ + YA G+L ++++ + E +
Sbjct: 86 HQLRREIEIQAHLQHPNILRLYNHFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTAT 145
Query: 619 WFRQMASGLQYLHSKNIAHRDLKCENILLSRRFNVKLA 732
++A L Y H K + HRD+K EN+LL R VK+A
Sbjct: 146 IIEELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIA 183
>U22456-1|AAA64850.1| 174|Homo sapiens AMP-activated protein kinase
homolog protein.
Length = 174
Score = 85.4 bits (202), Expect = 2e-16
Identities = 39/115 (33%), Positives = 67/115 (58%)
Frame = +1
Query: 388 LACKIFDKEKAPRDFLEKFFPRELEILTKIENPHIIQVHSILQRGPRVFIFMRYADNGDL 567
+A KI +++K + RE++ L +PHII+++ ++ +F+ M Y G+L
Sbjct: 18 VAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGEL 77
Query: 568 LDFIKRNGVVPENQAKLWFRQMASGLQYLHSKNIAHRDLKCENILLSRRFNVKLA 732
D+I +NG + E +++ F+Q+ SG+ Y H + HRDLK EN+LL N K+A
Sbjct: 78 FDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIA 132
>BC075064-1|AAH75064.2| 275|Homo sapiens AURKC protein protein.
Length = 275
Score = 85.0 bits (201), Expect = 2e-16
Identities = 42/143 (29%), Positives = 79/143 (55%)
Frame = +1
Query: 304 IGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKIEN 483
IG+ +G+G + V+LA + +A K+ K + ++ LE RE+EI +++
Sbjct: 11 IGRPLGKGKFGNVYLARLKES----HFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQH 66
Query: 484 PHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSK 663
P+I+++++ RV++ + YA G+L ++++ + E + ++A L Y H K
Sbjct: 67 PNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHDK 126
Query: 664 NIAHRDLKCENILLSRRFNVKLA 732
+ HRD+K EN+LL R VK+A
Sbjct: 127 KVIHRDIKPENLLLGFRGEVKIA 149
>AF059681-1|AAC77369.1| 275|Homo sapiens serine/threonine kinase 13
protein.
Length = 275
Score = 84.6 bits (200), Expect = 3e-16
Identities = 42/143 (29%), Positives = 79/143 (55%)
Frame = +1
Query: 304 IGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKIEN 483
IG+ +G+G + V+LA + +A K+ K + ++ LE RE+EI +++
Sbjct: 11 IGRPLGKGKFGNVYLARLKES----HFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQH 66
Query: 484 PHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSK 663
P+I+++++ RV++ + YA G+L ++++ + E + ++A L Y H K
Sbjct: 67 PNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEEVADALTYCHDK 126
Query: 664 NIAHRDLKCENILLSRRFNVKLA 732
+ HRD+K EN+LL R VK+A
Sbjct: 127 KVIHRDIKPENLLLGFRGEVKIA 149
>AJ271722-1|CAB71146.1| 714|Homo sapiens putative serine/threonine
protein kinase MAK-V protein.
Length = 714
Score = 83.8 bits (198), Expect = 6e-16
Identities = 49/146 (33%), Positives = 82/146 (56%), Gaps = 2/146 (1%)
Frame = +1
Query: 298 YLIG-KKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRD-FLEKFFPRELEILT 471
YLIG +K+G+GS+A V + +A K+ DK++A +D ++ K RE +I
Sbjct: 61 YLIGSRKLGEGSFAKVREGLHVLTGEK----VAIKVIDKKRAKKDTYVTKNLRREGQIQQ 116
Query: 472 KIENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQY 651
I +P+I Q+ IL+ ++ M G+L+ I + E++A+ + RQ+ S +++
Sbjct: 117 MIRHPNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLEESEARRYIRQLISAVEH 176
Query: 652 LHSKNIAHRDLKCENILLSRRFNVKL 729
LH + HRDLK EN+LL N+KL
Sbjct: 177 LHRAGVVHRDLKIENLLLDEDNNIKL 202
>AB006972-1|BAB69958.1| 970|Homo sapiens Sak protein.
Length = 970
Score = 83.8 bits (198), Expect = 6e-16
Identities = 45/147 (30%), Positives = 87/147 (59%), Gaps = 2/147 (1%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
+ +G +G+GS+A V+ AE S + +A K+ DK+ + + + E++I ++
Sbjct: 12 FKVGNLLGKGSFAGVYRAE----SIHSGLEVAIKMIDKKAMYKAGMVQRVQNEVKIHCQL 67
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVP--ENQAKLWFRQMASGLQY 651
++P I+++++ + V++ + NG++ ++K N V P EN+A+ + Q+ +G+ Y
Sbjct: 68 KHPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLK-NRVKPFSENEARHFMHQIITGMLY 126
Query: 652 LHSKNIAHRDLKCENILLSRRFNVKLA 732
LHS I HRDL N+LL+R N+K+A
Sbjct: 127 LHSHGILHRDLTLSNLLLTRNMNIKIA 153
>Y13115-1|CAA73575.1| 970|Homo sapiens serine/threonine protein
kinase protein.
Length = 970
Score = 83.4 bits (197), Expect = 8e-16
Identities = 45/147 (30%), Positives = 87/147 (59%), Gaps = 2/147 (1%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
+ +G +G+GS+A V+ AE S + +A K+ DK+ + + + E++I ++
Sbjct: 12 FKVGNLLGKGSFAGVYRAE----SIHTGLEVAIKMIDKKAMYKAGMVQRVKNEVKIHCQL 67
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVP--ENQAKLWFRQMASGLQY 651
++P I+++++ + V++ + NG++ ++K N V P EN+A+ + Q+ +G+ Y
Sbjct: 68 KHPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLK-NRVKPFSENEARHFMHQIITGMLY 126
Query: 652 LHSKNIAHRDLKCENILLSRRFNVKLA 732
LHS I HRDL N+LL+R N+K+A
Sbjct: 127 LHSHGILHRDLTLSNLLLTRNMNIKIA 153
>BC036023-1|AAH36023.1| 970|Homo sapiens polo-like kinase 4
(Drosophila) protein.
Length = 970
Score = 83.4 bits (197), Expect = 8e-16
Identities = 45/147 (30%), Positives = 87/147 (59%), Gaps = 2/147 (1%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
+ +G +G+GS+A V+ AE S + +A K+ DK+ + + + E++I ++
Sbjct: 12 FKVGNLLGKGSFAGVYRAE----SIHTGLEVAIKMIDKKAMYKAGMVQRVQNEVKIHCQL 67
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVP--ENQAKLWFRQMASGLQY 651
++P I+++++ + V++ + NG++ ++K N V P EN+A+ + Q+ +G+ Y
Sbjct: 68 KHPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLK-NRVKPFSENEARHFMHQIITGMLY 126
Query: 652 LHSKNIAHRDLKCENILLSRRFNVKLA 732
LHS I HRDL N+LL+R N+K+A
Sbjct: 127 LHSHGILHRDLTLSNLLLTRNMNIKIA 153
>D79997-1|BAA11492.2| 656|Homo sapiens KIAA0175 protein.
Length = 656
Score = 82.6 bits (195), Expect = 1e-15
Identities = 47/144 (32%), Positives = 76/144 (52%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y + + IG G +A V LA C + + + A KI DK D E+E L +
Sbjct: 16 YELHETIGTGGFAKVKLA--CHILTGEMV--AIKIMDKNTLGSDLPR--IKTEIEALKNL 69
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
+ HI Q++ +L+ ++F+ + Y G+L D+I + E + ++ FRQ+ S + Y+H
Sbjct: 70 RHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVH 129
Query: 658 SKNIAHRDLKCENILLSRRFNVKL 729
S+ AHRDLK EN+L +KL
Sbjct: 130 SQGYAHRDLKPENLLFDEYHKLKL 153
>BC014039-1|AAH14039.1| 651|Homo sapiens maternal embryonic leucine
zipper kinase protein.
Length = 651
Score = 82.6 bits (195), Expect = 1e-15
Identities = 47/144 (32%), Positives = 76/144 (52%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y + + IG G +A V LA C + + + A KI DK D E+E L +
Sbjct: 11 YELHETIGTGGFAKVKLA--CHILTGEMV--AIKIMDKNTLGSDLPR--IKTEIEALKNL 64
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
+ HI Q++ +L+ ++F+ + Y G+L D+I + E + ++ FRQ+ S + Y+H
Sbjct: 65 RHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVH 124
Query: 658 SKNIAHRDLKCENILLSRRFNVKL 729
S+ AHRDLK EN+L +KL
Sbjct: 125 SQGYAHRDLKPENLLFDEYHKLKL 148
>AL442063-1|CAI16995.2| 651|Homo sapiens maternal embryonic leucine
zipper kinase protein.
Length = 651
Score = 82.6 bits (195), Expect = 1e-15
Identities = 47/144 (32%), Positives = 76/144 (52%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y + + IG G +A V LA C + + + A KI DK D E+E L +
Sbjct: 11 YELHETIGTGGFAKVKLA--CHILTGEMV--AIKIMDKNTLGSDLPR--IKTEIEALKNL 64
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
+ HI Q++ +L+ ++F+ + Y G+L D+I + E + ++ FRQ+ S + Y+H
Sbjct: 65 RHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVH 124
Query: 658 SKNIAHRDLKCENILLSRRFNVKL 729
S+ AHRDLK EN+L +KL
Sbjct: 125 SQGYAHRDLKPENLLFDEYHKLKL 148
>AL354932-1|CAI11034.2| 651|Homo sapiens maternal embryonic leucine
zipper kinase protein.
Length = 651
Score = 82.6 bits (195), Expect = 1e-15
Identities = 47/144 (32%), Positives = 76/144 (52%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y + + IG G +A V LA C + + + A KI DK D E+E L +
Sbjct: 11 YELHETIGTGGFAKVKLA--CHILTGEMV--AIKIMDKNTLGSDLPR--IKTEIEALKNL 64
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
+ HI Q++ +L+ ++F+ + Y G+L D+I + E + ++ FRQ+ S + Y+H
Sbjct: 65 RHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVH 124
Query: 658 SKNIAHRDLKCENILLSRRFNVKL 729
S+ AHRDLK EN+L +KL
Sbjct: 125 SQGYAHRDLKPENLLFDEYHKLKL 148
>AK222811-1|BAD96531.1| 651|Homo sapiens maternal embryonic leucine
zipper kinase variant protein.
Length = 651
Score = 82.6 bits (195), Expect = 1e-15
Identities = 47/144 (32%), Positives = 76/144 (52%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y + + IG G +A V LA C + + + A KI DK D E+E L +
Sbjct: 11 YELHETIGTGGFAKVKLA--CHILTGEMV--AIKIMDKNTLGSDLPR--IKTEIEALKNL 64
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
+ HI Q++ +L+ ++F+ + Y G+L D+I + E + ++ FRQ+ S + Y+H
Sbjct: 65 RHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVH 124
Query: 658 SKNIAHRDLKCENILLSRRFNVKL 729
S+ AHRDLK EN+L +KL
Sbjct: 125 SQGYAHRDLKPENLLFDEYHKLKL 148
>BC036422-1|AAH36422.1| 436|Homo sapiens hypothetical protein
MGC42105 protein.
Length = 436
Score = 81.8 bits (193), Expect = 2e-15
Identities = 44/144 (30%), Positives = 80/144 (55%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y I +IG G+++ V L + S + +A KI DK K + ++ RE+ + K+
Sbjct: 74 YRIRGEIGSGNFSQVKLGIH----SLTKEKVAIKILDKTKLDQK-TQRLLSREISSMEKL 128
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
+P+II+++ +++ ++ + M YA G+L I G + E ++KL F Q+ S ++++H
Sbjct: 129 HHPNIIRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQIVSAVKHMH 188
Query: 658 SKNIAHRDLKCENILLSRRFNVKL 729
I HRDLK EN+ + VK+
Sbjct: 189 ENQIIHRDLKAENVFYTSNTCVKV 212
>BC031231-1|AAH31231.1| 514|Homo sapiens serine/threonine kinase 33
protein.
Length = 514
Score = 81.8 bits (193), Expect = 2e-15
Identities = 43/136 (31%), Positives = 76/136 (55%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y G+ +G+GS+ V E D + + A K +KEKA + K RE+ IL +
Sbjct: 116 YTFGRILGKGSFGIV--IEATDKETETKW--AIKKVNKEKAGSSAV-KLLEREVNILKSV 170
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
++ HII + + + ++++ M ++G+L + + R G EN+ + + +AS + YLH
Sbjct: 171 KHEHIIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLH 230
Query: 658 SKNIAHRDLKCENILL 705
+ +I HRDLK ENI++
Sbjct: 231 NNDIVHRDLKLENIMV 246
>AK093251-1|BAC04109.1| 514|Homo sapiens protein ( Homo sapiens
cDNA FLJ35932 fis, clone TESTI2011286, weakly similar to
MYOSIN LIGHT CHAIN KINASE (EC 2.7.1.117). ).
Length = 514
Score = 81.8 bits (193), Expect = 2e-15
Identities = 43/136 (31%), Positives = 76/136 (55%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y G+ +G+GS+ V E D + + A K +KEKA + K RE+ IL +
Sbjct: 116 YTFGRILGKGSFGIV--IEATDKETETKW--AIKKVNKEKAGSSAV-KLLEREVNILKSV 170
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
++ HII + + + ++++ M ++G+L + + R G EN+ + + +AS + YLH
Sbjct: 171 KHEHIIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLH 230
Query: 658 SKNIAHRDLKCENILL 705
+ +I HRDLK ENI++
Sbjct: 231 NNDIVHRDLKLENIMV 246
>AJ303380-1|CAC29064.1| 514|Homo sapiens serine/threonine kinase 33
protein.
Length = 514
Score = 81.8 bits (193), Expect = 2e-15
Identities = 43/136 (31%), Positives = 76/136 (55%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y G+ +G+GS+ V E D + + A K +KEKA + K RE+ IL +
Sbjct: 116 YTFGRILGKGSFGIV--IEATDKETETKW--AIKKVNKEKAGSSAV-KLLEREVNILKSV 170
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
++ HII + + + ++++ M ++G+L + + R G EN+ + + +AS + YLH
Sbjct: 171 KHEHIIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLH 230
Query: 658 SKNIAHRDLKCENILL 705
+ +I HRDLK ENI++
Sbjct: 231 NNDIVHRDLKLENIMV 246
>BT019534-1|AAV38341.1| 344|Homo sapiens serine/threonine kinase 12
protein.
Length = 344
Score = 79.8 bits (188), Expect = 9e-15
Identities = 40/145 (27%), Positives = 79/145 (54%), Gaps = 2/145 (1%)
Frame = +1
Query: 304 IGKKIGQGSYATVHLAEYCDGSSPKRMH--LACKIFDKEKAPRDFLEKFFPRELEILTKI 477
IG+ +G+G + V+LA K+ H +A K+ K + ++ +E RE+EI +
Sbjct: 79 IGRPLGKGKFGNVYLAR------EKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHL 132
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
+P+I+++++ R+++ + YA G+L ++++ E + ++A L Y H
Sbjct: 133 HHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCH 192
Query: 658 SKNIAHRDLKCENILLSRRFNVKLA 732
K + HRD+K EN+LL + +K+A
Sbjct: 193 GKKVIHRDIKPENLLLGLKGELKIA 217
>BC080581-1|AAH80581.1| 344|Homo sapiens aurora kinase B protein.
Length = 344
Score = 79.8 bits (188), Expect = 9e-15
Identities = 40/145 (27%), Positives = 79/145 (54%), Gaps = 2/145 (1%)
Frame = +1
Query: 304 IGKKIGQGSYATVHLAEYCDGSSPKRMH--LACKIFDKEKAPRDFLEKFFPRELEILTKI 477
IG+ +G+G + V+LA K+ H +A K+ K + ++ +E RE+EI +
Sbjct: 79 IGRPLGKGKFGNVYLAR------EKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHL 132
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
+P+I+++++ R+++ + YA G+L ++++ E + ++A L Y H
Sbjct: 133 HHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCH 192
Query: 658 SKNIAHRDLKCENILLSRRFNVKLA 732
K + HRD+K EN+LL + +K+A
Sbjct: 193 GKKVIHRDIKPENLLLGLKGELKIA 217
>BC013300-1|AAH13300.2| 371|Homo sapiens AURKB protein protein.
Length = 371
Score = 79.8 bits (188), Expect = 9e-15
Identities = 40/145 (27%), Positives = 79/145 (54%), Gaps = 2/145 (1%)
Frame = +1
Query: 304 IGKKIGQGSYATVHLAEYCDGSSPKRMH--LACKIFDKEKAPRDFLEKFFPRELEILTKI 477
IG+ +G+G + V+LA K+ H +A K+ K + ++ +E RE+EI +
Sbjct: 106 IGRPLGKGKFGNVYLAR------EKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHL 159
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
+P+I+++++ R+++ + YA G+L ++++ E + ++A L Y H
Sbjct: 160 HHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCH 219
Query: 658 SKNIAHRDLKCENILLSRRFNVKLA 732
K + HRD+K EN+LL + +K+A
Sbjct: 220 GKKVIHRDIKPENLLLGLKGELKIA 244
>BC009751-1|AAH09751.1| 344|Homo sapiens aurora kinase B protein.
Length = 344
Score = 79.8 bits (188), Expect = 9e-15
Identities = 40/145 (27%), Positives = 79/145 (54%), Gaps = 2/145 (1%)
Frame = +1
Query: 304 IGKKIGQGSYATVHLAEYCDGSSPKRMH--LACKIFDKEKAPRDFLEKFFPRELEILTKI 477
IG+ +G+G + V+LA K+ H +A K+ K + ++ +E RE+EI +
Sbjct: 79 IGRPLGKGKFGNVYLAR------EKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHL 132
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
+P+I+++++ R+++ + YA G+L ++++ E + ++A L Y H
Sbjct: 133 HHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCH 192
Query: 658 SKNIAHRDLKCENILLSRRFNVKLA 732
K + HRD+K EN+LL + +K+A
Sbjct: 193 GKKVIHRDIKPENLLLGLKGELKIA 217
>BC000442-1|AAH00442.3| 344|Homo sapiens aurora kinase B protein.
Length = 344
Score = 79.8 bits (188), Expect = 9e-15
Identities = 40/145 (27%), Positives = 79/145 (54%), Gaps = 2/145 (1%)
Frame = +1
Query: 304 IGKKIGQGSYATVHLAEYCDGSSPKRMH--LACKIFDKEKAPRDFLEKFFPRELEILTKI 477
IG+ +G+G + V+LA K+ H +A K+ K + ++ +E RE+EI +
Sbjct: 79 IGRPLGKGKFGNVYLAR------EKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHL 132
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
+P+I+++++ R+++ + YA G+L ++++ E + ++A L Y H
Sbjct: 133 HHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCH 192
Query: 658 SKNIAHRDLKCENILLSRRFNVKLA 732
K + HRD+K EN+LL + +K+A
Sbjct: 193 GKKVIHRDIKPENLLLGLKGELKIA 217
>AF159295-1|AAD48007.1| 752|Homo sapiens serine/threonine protein
kinase Kp78 splice variant CTAK75a protein.
Length = 752
Score = 79.8 bits (188), Expect = 9e-15
Identities = 51/168 (30%), Positives = 86/168 (51%), Gaps = 23/168 (13%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y + K IG+G++A V LA + +A KI DK + L+K F RE+ I+ +
Sbjct: 56 YRLLKTIGKGNFAKVKLARHILTGR----EVAIKIIDKTQLNPTSLQKLF-REVRIMKIL 110
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQ--------- 630
+P+I+++ +++ +++ M YA G++ D++ +G + E +A+ FRQ
Sbjct: 111 NHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGKMKEKEARSKFRQGCQAGQTIK 170
Query: 631 --------------MASGLQYLHSKNIAHRDLKCENILLSRRFNVKLA 732
+ S +QY H K I HRDLK EN+LL N+K+A
Sbjct: 171 VQVSFDLLSLMFTFIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIA 218
>AF008552-1|AAC12709.1| 344|Homo sapiens aurora-related kinase 2
protein.
Length = 344
Score = 79.8 bits (188), Expect = 9e-15
Identities = 40/145 (27%), Positives = 79/145 (54%), Gaps = 2/145 (1%)
Frame = +1
Query: 304 IGKKIGQGSYATVHLAEYCDGSSPKRMH--LACKIFDKEKAPRDFLEKFFPRELEILTKI 477
IG+ +G+G + V+LA K+ H +A K+ K + ++ +E RE+EI +
Sbjct: 79 IGRPLGKGKFGNVYLAR------EKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHL 132
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
+P+I+++++ R+++ + YA G+L ++++ E + ++A L Y H
Sbjct: 133 HHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCH 192
Query: 658 SKNIAHRDLKCENILLSRRFNVKLA 732
K + HRD+K EN+LL + +K+A
Sbjct: 193 GKKVIHRDIKPENLLLGLKGELKIA 217
>AB011450-1|BAA32136.1| 344|Homo sapiens aurora and IPL1-like
midbody-associated protein kinase-1 protein.
Length = 344
Score = 79.8 bits (188), Expect = 9e-15
Identities = 40/145 (27%), Positives = 79/145 (54%), Gaps = 2/145 (1%)
Frame = +1
Query: 304 IGKKIGQGSYATVHLAEYCDGSSPKRMH--LACKIFDKEKAPRDFLEKFFPRELEILTKI 477
IG+ +G+G + V+LA K+ H +A K+ K + ++ +E RE+EI +
Sbjct: 79 IGRPLGKGKFGNVYLAR------EKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHL 132
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
+P+I+++++ R+++ + YA G+L ++++ E + ++A L Y H
Sbjct: 133 HHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCH 192
Query: 658 SKNIAHRDLKCENILLSRRFNVKLA 732
K + HRD+K EN+LL + +K+A
Sbjct: 193 GKKVIHRDIKPENLLLGLKGELKIA 217
>AB011446-1|BAA82709.1| 343|Homo sapiens Aik2 protein.
Length = 343
Score = 79.8 bits (188), Expect = 9e-15
Identities = 40/145 (27%), Positives = 79/145 (54%), Gaps = 2/145 (1%)
Frame = +1
Query: 304 IGKKIGQGSYATVHLAEYCDGSSPKRMH--LACKIFDKEKAPRDFLEKFFPRELEILTKI 477
IG+ +G+G + V+LA K+ H +A K+ K + ++ +E RE+EI +
Sbjct: 79 IGRPLGKGKFGNVYLAR------EKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHL 132
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
+P+I+++++ R+++ + YA G+L ++++ E + ++A L Y H
Sbjct: 133 HHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCH 192
Query: 658 SKNIAHRDLKCENILLSRRFNVKLA 732
K + HRD+K EN+LL + +K+A
Sbjct: 193 GKKVIHRDIKPENLLLGLKGELKIA 217
>AB051552-1|BAB21856.1| 608|Homo sapiens KIAA1765 protein protein.
Length = 608
Score = 79.4 bits (187), Expect = 1e-14
Identities = 42/141 (29%), Positives = 71/141 (50%)
Frame = +1
Query: 289 QRGYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEIL 468
++ Y G+ IG G++A V + + R A KI DK + E E+ I+
Sbjct: 313 EKHYETGRVIGDGNFAVVKECRHRE----TRQAYAMKIIDKSRLKGK--EDMVDSEILII 366
Query: 469 TKIENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQ 648
+ +P+I+++H + + +++ + Y GDL D I + PE A L + L
Sbjct: 367 QSLSHPNIVKLHEVYETDMEIYLILEYVQGGDLFDAIIESVKFPEPDAALMIMDLCKALV 426
Query: 649 YLHSKNIAHRDLKCENILLSR 711
++H K+I HRDLK EN+L+ R
Sbjct: 427 HMHDKSIVHRDLKPENLLVQR 447
>D84212-1|BAA23592.1| 402|Homo sapiens aurora/IPL1-related kinase
protein.
Length = 402
Score = 79.0 bits (186), Expect = 2e-14
Identities = 45/162 (27%), Positives = 83/162 (51%)
Frame = +1
Query: 247 DRLSPRSSEVNALEQRGYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPR 426
+R E ALE + IG+ +G+G + V+LA + LA K+ K + +
Sbjct: 117 NRKMKNQKEAVALED--FEIGRPLGKGKFGNVYLAR----EKQSKFILALKVLFKAQLEK 170
Query: 427 DFLEKFFPRELEILTKIENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPEN 606
+E RE+EI + + +P+I++++ RV++ + YA G + +++ E
Sbjct: 171 AGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQ 230
Query: 607 QAKLWFRQMASGLQYLHSKNIAHRDLKCENILLSRRFNVKLA 732
+ + ++A+ L Y HSK + HRD+K EN+LL +K+A
Sbjct: 231 RTANLYNRIANALSYCHSKRVIHRDIKPENLLLGSAGELKIA 272
>BC111088-1|AAI11089.1| 252|Homo sapiens TSSK4 protein protein.
Length = 252
Score = 79.0 bits (186), Expect = 2e-14
Identities = 35/86 (40%), Positives = 55/86 (63%)
Frame = +1
Query: 475 IENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYL 654
+ + ++I + ++ RV+I + A GD+L++I+R G E A WF Q+ G+ YL
Sbjct: 4 LRHKYLINFYRAIESTSRVYIILELAQGGDVLEWIQRYGACSEPLAGKWFSQLTLGIAYL 63
Query: 655 HSKNIAHRDLKCENILLSRRFNVKLA 732
HSK+I HRDLK EN+LL + NVK++
Sbjct: 64 HSKSIVHRDLKLENLLLDKWENVKIS 89
>BC027464-1|AAH27464.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 79.0 bits (186), Expect = 2e-14
Identities = 40/143 (27%), Positives = 76/143 (53%)
Frame = +1
Query: 304 IGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKIEN 483
IG+ +G+G + V+LA + LA K+ K + + +E RE+EI + + +
Sbjct: 135 IGRPLGKGKFGNVYLAR----EKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRH 190
Query: 484 PHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSK 663
P+I++++ RV++ + YA G + +++ E + + ++A+ L Y HSK
Sbjct: 191 PNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSK 250
Query: 664 NIAHRDLKCENILLSRRFNVKLA 732
+ HRD+K EN+LL +K+A
Sbjct: 251 RVIHRDIKPENLLLGSAGELKIA 273
>BC006423-1|AAH06423.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 79.0 bits (186), Expect = 2e-14
Identities = 40/143 (27%), Positives = 76/143 (53%)
Frame = +1
Query: 304 IGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKIEN 483
IG+ +G+G + V+LA + LA K+ K + + +E RE+EI + + +
Sbjct: 135 IGRPLGKGKFGNVYLAR----EKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRH 190
Query: 484 PHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSK 663
P+I++++ RV++ + YA G + +++ E + + ++A+ L Y HSK
Sbjct: 191 PNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSK 250
Query: 664 NIAHRDLKCENILLSRRFNVKLA 732
+ HRD+K EN+LL +K+A
Sbjct: 251 RVIHRDIKPENLLLGSAGELKIA 273
>BC002499-1|AAH02499.1| 403|Homo sapiens AURKA protein protein.
Length = 403
Score = 79.0 bits (186), Expect = 2e-14
Identities = 40/143 (27%), Positives = 76/143 (53%)
Frame = +1
Query: 304 IGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKIEN 483
IG+ +G+G + V+LA + LA K+ K + + +E RE+EI + + +
Sbjct: 135 IGRPLGKGKFGNVYLAR----EKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRH 190
Query: 484 PHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSK 663
P+I++++ RV++ + YA G + +++ E + + ++A+ L Y HSK
Sbjct: 191 PNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSK 250
Query: 664 NIAHRDLKCENILLSRRFNVKLA 732
+ HRD+K EN+LL +K+A
Sbjct: 251 RVIHRDIKPENLLLGSAGELKIA 273
>BC001280-1|AAH01280.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 79.0 bits (186), Expect = 2e-14
Identities = 40/143 (27%), Positives = 76/143 (53%)
Frame = +1
Query: 304 IGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKIEN 483
IG+ +G+G + V+LA + LA K+ K + + +E RE+EI + + +
Sbjct: 135 IGRPLGKGKFGNVYLAR----EKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRH 190
Query: 484 PHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSK 663
P+I++++ RV++ + YA G + +++ E + + ++A+ L Y HSK
Sbjct: 191 PNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSK 250
Query: 664 NIAHRDLKCENILLSRRFNVKLA 732
+ HRD+K EN+LL +K+A
Sbjct: 251 RVIHRDIKPENLLLGSAGELKIA 273
>AL834498-1|CAD39156.1| 716|Homo sapiens hypothetical protein
protein.
Length = 716
Score = 79.0 bits (186), Expect = 2e-14
Identities = 51/148 (34%), Positives = 76/148 (51%)
Frame = +1
Query: 262 RSSEVNALEQRGYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEK 441
R SE + L ++ Y IGK IG G++A V E D S+ K A KI DK K E
Sbjct: 333 RCSESSTLLEK-YKIGKVIGDGNFAVVK--ECIDRSTGKEF--ALKIIDKAKCCGK--EH 385
Query: 442 FFPRELEILTKIENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLW 621
E+ IL ++++P+II + ++ +F+ M GDL D I + E
Sbjct: 386 LIENEVSILRRVKHPNIIMLVEEMETATELFLVMELVKGGDLFDAITSSTKYTERDGSAM 445
Query: 622 FRQMASGLQYLHSKNIAHRDLKCENILL 705
+A+ L+YLH +I HRD+K EN+L+
Sbjct: 446 VYNLANALRYLHGLSIVHRDIKPENLLV 473
>AL121914-4|CAM45838.1| 347|Homo sapiens aurora kinase A protein.
Length = 347
Score = 79.0 bits (186), Expect = 2e-14
Identities = 40/143 (27%), Positives = 76/143 (53%)
Frame = +1
Query: 304 IGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKIEN 483
IG+ +G+G + V+LA + LA K+ K + + +E RE+EI + + +
Sbjct: 135 IGRPLGKGKFGNVYLAR----EKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRH 190
Query: 484 PHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSK 663
P+I++++ RV++ + YA G + +++ E + + ++A+ L Y HSK
Sbjct: 191 PNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSK 250
Query: 664 NIAHRDLKCENILLSRRFNVKLA 732
+ HRD+K EN+LL +K+A
Sbjct: 251 RVIHRDIKPENLLLGSAGELKIA 273
>AL121914-3|CAC12717.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 79.0 bits (186), Expect = 2e-14
Identities = 40/143 (27%), Positives = 76/143 (53%)
Frame = +1
Query: 304 IGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKIEN 483
IG+ +G+G + V+LA + LA K+ K + + +E RE+EI + + +
Sbjct: 135 IGRPLGKGKFGNVYLAR----EKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRH 190
Query: 484 PHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSK 663
P+I++++ RV++ + YA G + +++ E + + ++A+ L Y HSK
Sbjct: 191 PNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSK 250
Query: 664 NIAHRDLKCENILLSRRFNVKLA 732
+ HRD+K EN+LL +K+A
Sbjct: 251 RVIHRDIKPENLLLGSAGELKIA 273
>AF195947-1|AAF29508.1| 403|Homo sapiens STK15 serine/threonine
kinase protein.
Length = 403
Score = 79.0 bits (186), Expect = 2e-14
Identities = 40/143 (27%), Positives = 76/143 (53%)
Frame = +1
Query: 304 IGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKIEN 483
IG+ +G+G + V+LA + LA K+ K + + +E RE+EI + + +
Sbjct: 135 IGRPLGKGKFGNVYLAR----EKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRH 190
Query: 484 PHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSK 663
P+I++++ RV++ + YA G + +++ E + + ++A+ L Y HSK
Sbjct: 191 PNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSK 250
Query: 664 NIAHRDLKCENILLSRRFNVKLA 732
+ HRD+K EN+LL +K+A
Sbjct: 251 RVIHRDIKPENLLLGSAGELKIA 273
>AF011468-1|AAC63902.1| 403|Homo sapiens serine/threonine kinase
protein.
Length = 403
Score = 79.0 bits (186), Expect = 2e-14
Identities = 40/143 (27%), Positives = 76/143 (53%)
Frame = +1
Query: 304 IGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKIEN 483
IG+ +G+G + V+LA + LA K+ K + + +E RE+EI + + +
Sbjct: 135 IGRPLGKGKFGNVYLAR----EKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRH 190
Query: 484 PHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSK 663
P+I++++ RV++ + YA G + +++ E + + ++A+ L Y HSK
Sbjct: 191 PNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSK 250
Query: 664 NIAHRDLKCENILLSRRFNVKLA 732
+ HRD+K EN+LL +K+A
Sbjct: 251 RVIHRDIKPENLLLGSAGELKIA 273
>AF008551-1|AAC12708.1| 403|Homo sapiens aurora-related kinase 1
protein.
Length = 403
Score = 79.0 bits (186), Expect = 2e-14
Identities = 40/143 (27%), Positives = 76/143 (53%)
Frame = +1
Query: 304 IGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKIEN 483
IG+ +G+G + V+LA + LA K+ K + + +E RE+EI + + +
Sbjct: 135 IGRPLGKGKFGNVYLAR----EKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRH 190
Query: 484 PHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSK 663
P+I++++ RV++ + YA G + +++ E + + ++A+ L Y HSK
Sbjct: 191 PNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSK 250
Query: 664 NIAHRDLKCENILLSRRFNVKLA 732
+ HRD+K EN+LL +K+A
Sbjct: 251 RVIHRDIKPENLLLGSAGELKIA 273
>AC093748-1|AAY40983.1| 443|Homo sapiens unknown protein.
Length = 443
Score = 79.0 bits (186), Expect = 2e-14
Identities = 51/148 (34%), Positives = 76/148 (51%)
Frame = +1
Query: 262 RSSEVNALEQRGYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEK 441
R SE + L ++ Y IGK IG G++A V E D S+ K A KI DK K E
Sbjct: 130 RCSESSTLLEK-YKIGKVIGDGNFAVVK--ECIDRSTGKEF--ALKIIDKAKCCGK--EH 182
Query: 442 FFPRELEILTKIENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLW 621
E+ IL ++++P+II + ++ +F+ M GDL D I + E
Sbjct: 183 LIENEVSILRRVKHPNIIMLVEEMETATELFLVMELVKGGDLFDAITSSTKYTERDGSAM 242
Query: 622 FRQMASGLQYLHSKNIAHRDLKCENILL 705
+A+ L+YLH +I HRD+K EN+L+
Sbjct: 243 VYNLANALRYLHGLSIVHRDIKPENLLV 270
>AB209181-1|BAD92418.1| 796|Homo sapiens Hypothetical protein
DKFZp761I032 variant protein.
Length = 796
Score = 79.0 bits (186), Expect = 2e-14
Identities = 51/148 (34%), Positives = 76/148 (51%)
Frame = +1
Query: 262 RSSEVNALEQRGYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEK 441
R SE + L ++ Y IGK IG G++A V E D S+ K A KI DK K E
Sbjct: 413 RCSESSTLLEK-YKIGKVIGDGNFAVVK--ECIDRSTGKEF--ALKIIDKAKCCGK--EH 465
Query: 442 FFPRELEILTKIENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLW 621
E+ IL ++++P+II + ++ +F+ M GDL D I + E
Sbjct: 466 LIENEVSILRRVKHPNIIMLVEEMETATELFLVMELVKGGDLFDAITSSTKYTERDGSAM 525
Query: 622 FRQMASGLQYLHSKNIAHRDLKCENILL 705
+A+ L+YLH +I HRD+K EN+L+
Sbjct: 526 VYNLANALRYLHGLSIVHRDIKPENLLV 553
>BC126432-1|AAI26433.1| 454|Homo sapiens death-associated protein
kinase 3 protein.
Length = 454
Score = 78.6 bits (185), Expect = 2e-14
Identities = 43/136 (31%), Positives = 70/136 (51%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y +G+++G G +A V G+ + K + R + RE+ IL +I
Sbjct: 13 YEMGEELGSGQFAIVRKCRQ-KGTGKEYAAKFIKKRRLSSSRRGVSREEIEREVNILREI 71
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
+P+II +H I + V + + G+L DF+ + E++A + +Q+ G+ YLH
Sbjct: 72 RHPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLH 131
Query: 658 SKNIAHRDLKCENILL 705
SK IAH DLK ENI+L
Sbjct: 132 SKRIAHFDLKPENIML 147
>BC126430-1|AAI26431.1| 454|Homo sapiens death-associated protein
kinase 3 protein.
Length = 454
Score = 78.6 bits (185), Expect = 2e-14
Identities = 43/136 (31%), Positives = 70/136 (51%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y +G+++G G +A V G+ + K + R + RE+ IL +I
Sbjct: 13 YEMGEELGSGQFAIVRKCRQ-KGTGKEYAAKFIKKRRLSSSRRGVSREEIEREVNILREI 71
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
+P+II +H I + V + + G+L DF+ + E++A + +Q+ G+ YLH
Sbjct: 72 RHPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLH 131
Query: 658 SKNIAHRDLKCENILL 705
SK IAH DLK ENI+L
Sbjct: 132 SKRIAHFDLKPENIML 147
>AB022341-1|BAA81746.1| 454|Homo sapiens ZIP kinase protein.
Length = 454
Score = 78.6 bits (185), Expect = 2e-14
Identities = 43/136 (31%), Positives = 70/136 (51%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y +G+++G G +A V G+ + K + R + RE+ IL +I
Sbjct: 13 YEMGEELGSGQFAIVRKCRQ-KGTGKEYAAKFIKKRRLSSSRRGVSREEIEREVNILREI 71
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
+P+II +H I + V + + G+L DF+ + E++A + +Q+ G+ YLH
Sbjct: 72 RHPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLH 131
Query: 658 SKNIAHRDLKCENILL 705
SK IAH DLK ENI+L
Sbjct: 132 SKRIAHFDLKPENIML 147
>AB007144-1|BAA24955.1| 454|Homo sapiens ZIP-kinase protein.
Length = 454
Score = 78.6 bits (185), Expect = 2e-14
Identities = 43/136 (31%), Positives = 70/136 (51%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y +G+++G G +A V G+ + K + R + RE+ IL +I
Sbjct: 13 YEMGEELGSGQFAIVRKCRQ-KGTGKEYAAKFIKKRRLSSSRRGVSREEIEREVNILREI 71
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
+P+II +H I + V + + G+L DF+ + E++A + +Q+ G+ YLH
Sbjct: 72 RHPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLH 131
Query: 658 SKNIAHRDLKCENILL 705
SK IAH DLK ENI+L
Sbjct: 132 SKRIAHFDLKPENIML 147
>AK027302-1|BAB55026.1| 208|Homo sapiens protein ( Homo sapiens
cDNA FLJ14396 fis, clone HEMBA1003291, moderately
similar to SNF1-RELATED PROTEIN KINASE KIN10 (EC
2.7.1.-). ).
Length = 208
Score = 78.2 bits (184), Expect = 3e-14
Identities = 39/130 (30%), Positives = 70/130 (53%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y + + +G+G+Y V A + S + + + DK K +D + RE+EI++ +
Sbjct: 55 YELQETLGKGTYGKVKRAT--ERFSGRVVAIKSVRKDKIKDEQDMVH--IRREIEIMSSL 110
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLH 657
+PHII ++ + + ++ I M YA G+L D+I + E + + +FRQ+ S + Y H
Sbjct: 111 NHPHIISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCH 170
Query: 658 SKNIAHRDLK 687
+ HRDLK
Sbjct: 171 KNGVVHRDLK 180
>AJ006701-1|CAA07196.1| 603|Homo sapiens putative serine/threonine
protein kinase protein.
Length = 603
Score = 78.2 bits (184), Expect = 3e-14
Identities = 29/86 (33%), Positives = 57/86 (66%)
Frame = +1
Query: 475 IENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYL 654
IE+PH++++H + + +++ + + G+L D++ + G + +A+ +FRQ+ S L +
Sbjct: 2 IEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFC 61
Query: 655 HSKNIAHRDLKCENILLSRRFNVKLA 732
HS +I HRDLK EN+LL + N+++A
Sbjct: 62 HSHSICHRDLKPENLLLDEKNNIRIA 87
>AC005793-1|AAC62830.1| 593|Homo sapiens KIAA0561 protein [AA 1-
593] protein.
Length = 593
Score = 77.8 bits (183), Expect = 4e-14
Identities = 44/141 (31%), Positives = 75/141 (53%), Gaps = 1/141 (0%)
Frame = +1
Query: 310 KKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAP-RDFLEKFFPRELEILTKIENP 486
K I G+Y V+L + D R A K +K+ R+ +++ F E +ILT ENP
Sbjct: 370 KLISNGAYGAVYLVRHRD----TRQRFAIKKINKQNLILRNQIQQVFV-ERDILTFAENP 424
Query: 487 HIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKN 666
++ + + + + M Y + GD +K G +P + A+L+F + L+YLH+
Sbjct: 425 FVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPVDMARLYFAETVLALEYLHNYG 484
Query: 667 IAHRDLKCENILLSRRFNVKL 729
I HRDLK +N+L++ ++KL
Sbjct: 485 IVHRDLKPDNLLITSLGHIKL 505
>AB011133-1|BAA25487.1| 1308|Homo sapiens KIAA0561 protein protein.
Length = 1308
Score = 77.8 bits (183), Expect = 4e-14
Identities = 44/141 (31%), Positives = 75/141 (53%), Gaps = 1/141 (0%)
Frame = +1
Query: 310 KKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAP-RDFLEKFFPRELEILTKIENP 486
K I G+Y V+L + D R A K +K+ R+ +++ F E +ILT ENP
Sbjct: 370 KLISNGAYGAVYLVRHRD----TRQRFAIKKINKQNLILRNQIQQVFV-ERDILTFAENP 424
Query: 487 HIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKN 666
++ + + + + M Y + GD +K G +P + A+L+F + L+YLH+
Sbjct: 425 FVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPVDMARLYFAETVLALEYLHNYG 484
Query: 667 IAHRDLKCENILLSRRFNVKL 729
I HRDLK +N+L++ ++KL
Sbjct: 485 IVHRDLKPDNLLITSLGHIKL 505
>BC034988-1|AAH34988.1| 1036|Homo sapiens ULK2 protein protein.
Length = 1036
Score = 77.4 bits (182), Expect = 5e-14
Identities = 38/131 (29%), Positives = 76/131 (58%)
Frame = +1
Query: 316 IGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKIENPHII 495
+G G++A V + + +A K +K+ + + +E++IL ++++ +I+
Sbjct: 15 VGHGAFAVVFRGRHRQKTD---WEVAIKSINKKNLSKSQI--LLGKEIKILKELQHENIV 69
Query: 496 QVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKNIAH 675
++ + + VF+ M Y + GDL D+++ G + E+ +++ Q+A+ ++ LHSK I H
Sbjct: 70 ALYDVQELPNSVFLVMEYCNGGDLADYLQAKGTLSEDTIRVFLHQIAAAMRILHSKGIIH 129
Query: 676 RDLKCENILLS 708
RDLK +NILLS
Sbjct: 130 RDLKPQNILLS 140
>BC028587-1|AAH28587.1| 482|Homo sapiens NEK11 protein protein.
Length = 482
Score = 77.4 bits (182), Expect = 5e-14
Identities = 46/151 (30%), Positives = 78/151 (51%), Gaps = 4/151 (2%)
Frame = +1
Query: 265 SSEVNALEQRGYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKF 444
S+ L R Y++ +K+G GS+ TV+L + + + +I E P + ++
Sbjct: 18 STYPKTLIARRYVLQQKLGSGSFGTVYLVSDKKAKRGEELKVLKEISVGELNPNETVQAN 77
Query: 445 FPRELEILTKIENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFI---KRNG-VVPENQA 612
E ++L+K+++P I++ H+ I Y + DL D I K+ G + PENQ
Sbjct: 78 L--EAQLLSKLDHPAIVKFHASFVEQDNFCIITEYCEGRDLDDKIQEYKQAGKIFPENQI 135
Query: 613 KLWFRQMASGLQYLHSKNIAHRDLKCENILL 705
WF Q+ G+ Y+H + I HRDLK +N+ L
Sbjct: 136 IEWFIQLLLGVDYMHERRILHRDLKSKNVFL 166
>BC019916-1|AAH19916.2| 506|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 3 protein.
Length = 506
Score = 77.4 bits (182), Expect = 5e-14
Identities = 45/147 (30%), Positives = 77/147 (52%), Gaps = 3/147 (2%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPR-ELEILTK 474
Y++ + IG+GS+ L ++ S +M +I + P+ F R E +L K
Sbjct: 4 YMVLRMIGEGSFGRALLVQH---ESSNQMFAMKEI----RLPKSFSNTQNSRKEAVLLAK 56
Query: 475 IENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIK--RNGVVPENQAKLWFRQMASGLQ 648
+++P+I+ + ++I M Y D GDL+ IK + + PE+ WF QM G+
Sbjct: 57 MKHPNIVAFKESFEAEGHLYIVMEYCDGGDLMQKIKQQKGKLFPEDMILNWFTQMCLGVN 116
Query: 649 YLHSKNIAHRDLKCENILLSRRFNVKL 729
++H K + HRD+K +NI L++ VKL
Sbjct: 117 HIHKKRVLHRDIKSKNIFLTQNGKVKL 143
>AL139082-7|CAI12895.1| 507|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 3 protein.
Length = 507
Score = 77.4 bits (182), Expect = 5e-14
Identities = 45/147 (30%), Positives = 77/147 (52%), Gaps = 3/147 (2%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPR-ELEILTK 474
Y++ + IG+GS+ L ++ S +M +I + P+ F R E +L K
Sbjct: 4 YMVLRMIGEGSFGRALLVQH---ESSNQMFAMKEI----RLPKSFSNTQNSRKEAVLLAK 56
Query: 475 IENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIK--RNGVVPENQAKLWFRQMASGLQ 648
+++P+I+ + ++I M Y D GDL+ IK + + PE+ WF QM G+
Sbjct: 57 MKHPNIVAFKESFEAEGHLYIVMEYCDGGDLMQKIKQQKGKLFPEDMILNWFTQMCLGVN 116
Query: 649 YLHSKNIAHRDLKCENILLSRRFNVKL 729
++H K + HRD+K +NI L++ VKL
Sbjct: 117 HIHKKRVLHRDIKSKNIFLTQNGKVKL 143
>AK131359-1|BAD18511.1| 510|Homo sapiens protein ( Homo sapiens
cDNA FLJ16392 fis, clone TRACH2020048, moderately
similar to Mus musculus serine/threonine-protein kinase
NEK3 (Nek3) mRNA. ).
Length = 510
Score = 77.4 bits (182), Expect = 5e-14
Identities = 45/147 (30%), Positives = 77/147 (52%), Gaps = 3/147 (2%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPR-ELEILTK 474
Y++ + IG+GS+ L ++ S +M +I + P+ F R E +L K
Sbjct: 25 YMVLRMIGEGSFGRALLVQH---ESSNQMFAMKEI----RLPKSFSNTQNSRKEAVLLAK 77
Query: 475 IENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIK--RNGVVPENQAKLWFRQMASGLQ 648
+++P+I+ + ++I M Y D GDL+ IK + + PE+ WF QM G+
Sbjct: 78 MKHPNIVAFKESFEAEGHLYIVMEYCDGGDLMQKIKQQKGKLFPEDMILNWFTQMCLGVN 137
Query: 649 YLHSKNIAHRDLKCENILLSRRFNVKL 729
++H K + HRD+K +NI L++ VKL
Sbjct: 138 HIHKKRVLHRDIKSKNIFLTQNGKVKL 164
>AB071997-1|BAC06351.1| 470|Homo sapiens NIMA-related kinase 11S
protein.
Length = 470
Score = 77.4 bits (182), Expect = 5e-14
Identities = 46/151 (30%), Positives = 78/151 (51%), Gaps = 4/151 (2%)
Frame = +1
Query: 265 SSEVNALEQRGYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKF 444
S+ L R Y++ +K+G GS+ TV+L + + + +I E P + ++
Sbjct: 18 STYPKTLIARRYVLQQKLGSGSFGTVYLVSDKKAKRGEELKVLKEISVGELNPNETVQAN 77
Query: 445 FPRELEILTKIENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFI---KRNG-VVPENQA 612
E ++L+K+++P I++ H+ I Y + DL D I K+ G + PENQ
Sbjct: 78 L--EAQLLSKLDHPAIVKFHASFVEQDNFCIITEYCEGRDLDDKIQEYKQAGKIFPENQI 135
Query: 613 KLWFRQMASGLQYLHSKNIAHRDLKCENILL 705
WF Q+ G+ Y+H + I HRDLK +N+ L
Sbjct: 136 IEWFIQLLLGVDYMHERRILHRDLKSKNVFL 166
>AB071996-1|BAC06350.1| 645|Homo sapiens NIMA-related kinase 11L
protein.
Length = 645
Score = 77.4 bits (182), Expect = 5e-14
Identities = 46/151 (30%), Positives = 78/151 (51%), Gaps = 4/151 (2%)
Frame = +1
Query: 265 SSEVNALEQRGYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKF 444
S+ L R Y++ +K+G GS+ TV+L + + + +I E P + ++
Sbjct: 18 STYPKTLIARRYVLQQKLGSGSFGTVYLVSDKKAKRGEELKVLKEISVGELNPNETVQAN 77
Query: 445 FPRELEILTKIENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFI---KRNG-VVPENQA 612
E ++L+K+++P I++ H+ I Y + DL D I K+ G + PENQ
Sbjct: 78 L--EAQLLSKLDHPAIVKFHASFVEQDNFCIITEYCEGRDLDDKIQEYKQAGKIFPENQI 135
Query: 613 KLWFRQMASGLQYLHSKNIAHRDLKCENILL 705
WF Q+ G+ Y+H + I HRDLK +N+ L
Sbjct: 136 IEWFIQLLLGVDYMHERRILHRDLKSKNVFL 166
>AB014523-1|BAA31598.2| 1100|Homo sapiens KIAA0623 protein protein.
Length = 1100
Score = 77.4 bits (182), Expect = 5e-14
Identities = 38/131 (29%), Positives = 76/131 (58%)
Frame = +1
Query: 316 IGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKIENPHII 495
+G G++A V + + +A K +K+ + + +E++IL ++++ +I+
Sbjct: 79 VGHGAFAVVFRGRHRQKTD---WEVAIKSINKKNLSKSQI--LLGKEIKILKELQHENIV 133
Query: 496 QVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKNIAH 675
++ + + VF+ M Y + GDL D+++ G + E+ +++ Q+A+ ++ LHSK I H
Sbjct: 134 ALYDVQELPNSVFLVMEYCNGGDLADYLQAKGTLSEDTIRVFLHQIAAAMRILHSKGIIH 193
Query: 676 RDLKCENILLS 708
RDLK +NILLS
Sbjct: 194 RDLKPQNILLS 204
>Y10256-1|CAA71306.1| 947|Homo sapiens NIK, serine/threonine
protein-kinase protein.
Length = 947
Score = 77.0 bits (181), Expect = 7e-14
Identities = 45/132 (34%), Positives = 69/132 (52%)
Frame = +1
Query: 313 KIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKIENPHI 492
++G+GS+ VH E K+ C + K R LE F EL + +P I
Sbjct: 405 RLGRGSFGEVHRME------DKQTGFQCAV----KKVR--LEVFRAEELMACAGLTSPRI 452
Query: 493 IQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKNIA 672
+ ++ ++ GP V IFM + G L +K G +PE++A + Q GL+YLHS+ I
Sbjct: 453 VPLYGAVREGPWVNIFMELLEGGSLGQLVKEQGCLPEDRALYYLGQALEGLEYLHSRRIL 512
Query: 673 HRDLKCENILLS 708
H D+K +N+LLS
Sbjct: 513 HGDVKADNVLLS 524
>U08316-1|AAA81952.1| 740|Homo sapiens insulin-stimulated protein
kinase 1 protein.
Length = 740
Score = 77.0 bits (181), Expect = 7e-14
Identities = 43/141 (30%), Positives = 75/141 (53%), Gaps = 1/141 (0%)
Frame = +1
Query: 310 KKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAP-RDFLEKFFPRELEILTKIENP 486
K +GQGS+ V L + GS ++++ A K+ K RD + R+ IL ++ +P
Sbjct: 72 KVLGQGSFGKVFLVKKISGSDARQLY-AMKVLKKATLKVRDRVRTKMERD--ILVEVNHP 128
Query: 487 HIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKN 666
I+++H Q ++++ + + GDL + + + E K + ++A L +LHS
Sbjct: 129 FIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLG 188
Query: 667 IAHRDLKCENILLSRRFNVKL 729
I +RDLK ENILL ++KL
Sbjct: 189 IIYRDLKPENILLDEEGHIKL 209
Score = 64.9 bits (151), Expect = 3e-10
Identities = 46/137 (33%), Positives = 69/137 (50%), Gaps = 1/137 (0%)
Frame = +1
Query: 295 GYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTK 474
GY + + IG GSY+ + + C + M A KI DK K RD E E+EIL +
Sbjct: 421 GYEVKEDIGVGSYS---VCKRCIHKATN-MEFAVKIIDKSK--RDPTE-----EIEILLR 469
Query: 475 I-ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQY 651
++P+II + + G V++ G+LLD I R E +A + ++Y
Sbjct: 470 YGQHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEY 529
Query: 652 LHSKNIAHRDLKCENIL 702
LH++ + HRDLK NIL
Sbjct: 530 LHAQGVVHRDLKPSNIL 546
>L07599-1|AAC82495.1| 580|Homo sapiens ribosomal protein S6 kinase
3 protein.
Length = 580
Score = 77.0 bits (181), Expect = 7e-14
Identities = 43/141 (30%), Positives = 75/141 (53%), Gaps = 1/141 (0%)
Frame = +1
Query: 310 KKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAP-RDFLEKFFPRELEILTKIENP 486
K +GQGS+ V L + GS ++++ A K+ K RD + R+ IL ++ +P
Sbjct: 71 KVLGQGSFGKVFLVKKISGSDARQLY-AMKVLKKATLKVRDRVRTKMERD--ILVEVNHP 127
Query: 487 HIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKN 666
I+++H Q ++++ + + GDL + + + E K + ++A L +LHS
Sbjct: 128 FIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLG 187
Query: 667 IAHRDLKCENILLSRRFNVKL 729
I +RDLK ENILL ++KL
Sbjct: 188 IIYRDLKPENILLDEEGHIKL 208
Score = 61.7 bits (143), Expect = 3e-09
Identities = 46/137 (33%), Positives = 71/137 (51%), Gaps = 1/137 (0%)
Frame = +1
Query: 295 GYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTK 474
GY + + IG GSY+ + + C + M A KI DK K RD E E+EIL +
Sbjct: 420 GYELKEDIGVGSYS---VCKRCIHKATN-MEFAVKIIDKSK--RDPTE-----EIEILLR 468
Query: 475 I-ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQY 651
++P+II ++ + G V++ + G+LLD I R E +A + ++Y
Sbjct: 469 YGQHPNIITLNDVYDDGKYVYV-VTLMKGGELLDKILRQKFFSEREASAVLFTITKTVEY 527
Query: 652 LHSKNIAHRDLKCENIL 702
LH++ + HRDLK NIL
Sbjct: 528 LHAQGVVHRDLKPSNIL 544
>DQ314874-1|ABC40733.1| 947|Homo sapiens mitogen-activated protein
kinase kinase kinase 14 protein.
Length = 947
Score = 77.0 bits (181), Expect = 7e-14
Identities = 45/132 (34%), Positives = 69/132 (52%)
Frame = +1
Query: 313 KIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKIENPHI 492
++G+GS+ VH E K+ C + K R LE F EL + +P I
Sbjct: 405 RLGRGSFGEVHRME------DKQTGFQCAV----KKVR--LEVFRAEELMACAGLTSPRI 452
Query: 493 IQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKNIA 672
+ ++ ++ GP V IFM + G L +K G +PE++A + Q GL+YLHS+ I
Sbjct: 453 VPLYGAVREGPWVNIFMELLEGGSLGQLVKEQGCLPEDRALYYLGQALEGLEYLHSRRIL 512
Query: 673 HRDLKCENILLS 708
H D+K +N+LLS
Sbjct: 513 HGDVKADNVLLS 524
>BC096302-1|AAH96302.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 77.0 bits (181), Expect = 7e-14
Identities = 43/141 (30%), Positives = 75/141 (53%), Gaps = 1/141 (0%)
Frame = +1
Query: 310 KKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAP-RDFLEKFFPRELEILTKIENP 486
K +GQGS+ V L + GS ++++ A K+ K RD + R+ IL ++ +P
Sbjct: 72 KVLGQGSFGKVFLVKKISGSDARQLY-AMKVLKKATLKVRDRVRTKMERD--ILVEVNHP 128
Query: 487 HIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKN 666
I+++H Q ++++ + + GDL + + + E K + ++A L +LHS
Sbjct: 129 FIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLG 188
Query: 667 IAHRDLKCENILLSRRFNVKL 729
I +RDLK ENILL ++KL
Sbjct: 189 IIYRDLKPENILLDEEGHIKL 209
Score = 64.9 bits (151), Expect = 3e-10
Identities = 46/137 (33%), Positives = 69/137 (50%), Gaps = 1/137 (0%)
Frame = +1
Query: 295 GYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTK 474
GY + + IG GSY+ + + C + M A KI DK K RD E E+EIL +
Sbjct: 421 GYEVKEDIGVGSYS---VCKRCIHKATN-MEFAVKIIDKSK--RDPTE-----EIEILLR 469
Query: 475 I-ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQY 651
++P+II + + G V++ G+LLD I R E +A + ++Y
Sbjct: 470 YGQHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEY 529
Query: 652 LHSKNIAHRDLKCENIL 702
LH++ + HRDLK NIL
Sbjct: 530 LHAQGVVHRDLKPSNIL 546
>BC096301-1|AAH96301.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 77.0 bits (181), Expect = 7e-14
Identities = 43/141 (30%), Positives = 75/141 (53%), Gaps = 1/141 (0%)
Frame = +1
Query: 310 KKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAP-RDFLEKFFPRELEILTKIENP 486
K +GQGS+ V L + GS ++++ A K+ K RD + R+ IL ++ +P
Sbjct: 72 KVLGQGSFGKVFLVKKISGSDARQLY-AMKVLKKATLKVRDRVRTKMERD--ILVEVNHP 128
Query: 487 HIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKN 666
I+++H Q ++++ + + GDL + + + E K + ++A L +LHS
Sbjct: 129 FIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLG 188
Query: 667 IAHRDLKCENILLSRRFNVKL 729
I +RDLK ENILL ++KL
Sbjct: 189 IIYRDLKPENILLDEEGHIKL 209
Score = 64.9 bits (151), Expect = 3e-10
Identities = 46/137 (33%), Positives = 69/137 (50%), Gaps = 1/137 (0%)
Frame = +1
Query: 295 GYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTK 474
GY + + IG GSY+ + + C + M A KI DK K RD E E+EIL +
Sbjct: 421 GYEVKEDIGVGSYS---VCKRCIHKATN-MEFAVKIIDKSK--RDPTE-----EIEILLR 469
Query: 475 I-ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQY 651
++P+II + + G V++ G+LLD I R E +A + ++Y
Sbjct: 470 YGQHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEY 529
Query: 652 LHSKNIAHRDLKCENIL 702
LH++ + HRDLK NIL
Sbjct: 530 LHAQGVVHRDLKPSNIL 546
>BC035576-1|AAH35576.1| 947|Homo sapiens mitogen-activated protein
kinase kinase kinase 14 protein.
Length = 947
Score = 77.0 bits (181), Expect = 7e-14
Identities = 45/132 (34%), Positives = 69/132 (52%)
Frame = +1
Query: 313 KIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKIENPHI 492
++G+GS+ VH E K+ C + K R LE F EL + +P I
Sbjct: 405 RLGRGSFGEVHRME------DKQTGFQCAV----KKVR--LEVFRAEELMACAGLTSPRI 452
Query: 493 IQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKNIA 672
+ ++ ++ GP V IFM + G L +K G +PE++A + Q GL+YLHS+ I
Sbjct: 453 VPLYGAVREGPWVNIFMELLEGGSLGQLVKEQGCLPEDRALYYLGQALEGLEYLHSRRIL 512
Query: 673 HRDLKCENILLS 708
H D+K +N+LLS
Sbjct: 513 HGDVKADNVLLS 524
>AL807772-3|CAI39687.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 77.0 bits (181), Expect = 7e-14
Identities = 43/141 (30%), Positives = 75/141 (53%), Gaps = 1/141 (0%)
Frame = +1
Query: 310 KKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAP-RDFLEKFFPRELEILTKIENP 486
K +GQGS+ V L + GS ++++ A K+ K RD + R+ IL ++ +P
Sbjct: 72 KVLGQGSFGKVFLVKKISGSDARQLY-AMKVLKKATLKVRDRVRTKMERD--ILVEVNHP 128
Query: 487 HIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKN 666
I+++H Q ++++ + + GDL + + + E K + ++A L +LHS
Sbjct: 129 FIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLG 188
Query: 667 IAHRDLKCENILLSRRFNVKL 729
I +RDLK ENILL ++KL
Sbjct: 189 IIYRDLKPENILLDEEGHIKL 209
Score = 64.9 bits (151), Expect = 3e-10
Identities = 46/137 (33%), Positives = 69/137 (50%), Gaps = 1/137 (0%)
Frame = +1
Query: 295 GYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTK 474
GY + + IG GSY+ + + C + M A KI DK K RD E E+EIL +
Sbjct: 421 GYEVKEDIGVGSYS---VCKRCIHKATN-MEFAVKIIDKSK--RDPTE-----EIEILLR 469
Query: 475 I-ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQY 651
++P+II + + G V++ G+LLD I R E +A + ++Y
Sbjct: 470 YGQHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEY 529
Query: 652 LHSKNIAHRDLKCENIL 702
LH++ + HRDLK NIL
Sbjct: 530 LHAQGVVHRDLKPSNIL 546
>AL807772-1|CAI39684.1| 227|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 227
Score = 77.0 bits (181), Expect = 7e-14
Identities = 43/141 (30%), Positives = 75/141 (53%), Gaps = 1/141 (0%)
Frame = +1
Query: 310 KKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAP-RDFLEKFFPRELEILTKIENP 486
K +GQGS+ V L + GS ++++ A K+ K RD + R+ IL ++ +P
Sbjct: 43 KVLGQGSFGKVFLVKKISGSDARQLY-AMKVLKKATLKVRDRVRTKMERD--ILVEVNHP 99
Query: 487 HIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKN 666
I+++H Q ++++ + + GDL + + + E K + ++A L +LHS
Sbjct: 100 FIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLG 159
Query: 667 IAHRDLKCENILLSRRFNVKL 729
I +RDLK ENILL ++KL
Sbjct: 160 IIYRDLKPENILLDEEGHIKL 180
>AL732366-2|CAI40548.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 77.0 bits (181), Expect = 7e-14
Identities = 43/141 (30%), Positives = 75/141 (53%), Gaps = 1/141 (0%)
Frame = +1
Query: 310 KKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAP-RDFLEKFFPRELEILTKIENP 486
K +GQGS+ V L + GS ++++ A K+ K RD + R+ IL ++ +P
Sbjct: 72 KVLGQGSFGKVFLVKKISGSDARQLY-AMKVLKKATLKVRDRVRTKMERD--ILVEVNHP 128
Query: 487 HIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKN 666
I+++H Q ++++ + + GDL + + + E K + ++A L +LHS
Sbjct: 129 FIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLG 188
Query: 667 IAHRDLKCENILLSRRFNVKL 729
I +RDLK ENILL ++KL
Sbjct: 189 IIYRDLKPENILLDEEGHIKL 209
Score = 64.9 bits (151), Expect = 3e-10
Identities = 46/137 (33%), Positives = 69/137 (50%), Gaps = 1/137 (0%)
Frame = +1
Query: 295 GYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTK 474
GY + + IG GSY+ + + C + M A KI DK K RD E E+EIL +
Sbjct: 421 GYEVKEDIGVGSYS---VCKRCIHKATN-MEFAVKIIDKSK--RDPTE-----EIEILLR 469
Query: 475 I-ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQY 651
++P+II + + G V++ G+LLD I R E +A + ++Y
Sbjct: 470 YGQHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEY 529
Query: 652 LHSKNIAHRDLKCENIL 702
LH++ + HRDLK NIL
Sbjct: 530 LHAQGVVHRDLKPSNIL 546
>AB208933-1|BAD92170.1| 806|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 variant protein.
Length = 806
Score = 77.0 bits (181), Expect = 7e-14
Identities = 43/141 (30%), Positives = 75/141 (53%), Gaps = 1/141 (0%)
Frame = +1
Query: 310 KKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAP-RDFLEKFFPRELEILTKIENP 486
K +GQGS+ V L + GS ++++ A K+ K RD + R+ IL ++ +P
Sbjct: 139 KVLGQGSFGKVFLVKKISGSDARQLY-AMKVLKKATLKVRDRVRTKMERD--ILVEVNHP 195
Query: 487 HIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKN 666
I+++H Q ++++ + + GDL + + + E K + ++A L +LHS
Sbjct: 196 FIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLG 255
Query: 667 IAHRDLKCENILLSRRFNVKL 729
I +RDLK ENILL ++KL
Sbjct: 256 IIYRDLKPENILLDEEGHIKL 276
Score = 64.9 bits (151), Expect = 3e-10
Identities = 46/137 (33%), Positives = 69/137 (50%), Gaps = 1/137 (0%)
Frame = +1
Query: 295 GYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTK 474
GY + + IG GSY+ + + C + M A KI DK K RD E E+EIL +
Sbjct: 487 GYEVKEDIGVGSYS---VCKRCIHKATN-MEFAVKIIDKSK--RDPTE-----EIEILLR 535
Query: 475 I-ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQY 651
++P+II + + G V++ G+LLD I R E +A + ++Y
Sbjct: 536 YGQHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEY 595
Query: 652 LHSKNIAHRDLKCENIL 702
LH++ + HRDLK NIL
Sbjct: 596 LHAQGVVHRDLKPSNIL 612
>AB102662-1|BAC81131.1| 726|Homo sapiens RPS6KA3 protein.
Length = 726
Score = 77.0 bits (181), Expect = 7e-14
Identities = 43/141 (30%), Positives = 75/141 (53%), Gaps = 1/141 (0%)
Frame = +1
Query: 310 KKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAP-RDFLEKFFPRELEILTKIENP 486
K +GQGS+ V L + GS ++++ A K+ K RD + R+ IL ++ +P
Sbjct: 58 KVLGQGSFGKVFLVKKISGSDARQLY-AMKVLKKATLKVRDRVRTKMERD--ILVEVNHP 114
Query: 487 HIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKN 666
I+++H Q ++++ + + GDL + + + E K + ++A L +LHS
Sbjct: 115 FIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLG 174
Query: 667 IAHRDLKCENILLSRRFNVKL 729
I +RDLK ENILL ++KL
Sbjct: 175 IIYRDLKPENILLDEEGHIKL 195
Score = 64.9 bits (151), Expect = 3e-10
Identities = 46/137 (33%), Positives = 69/137 (50%), Gaps = 1/137 (0%)
Frame = +1
Query: 295 GYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTK 474
GY + + IG GSY+ + + C + M A KI DK K RD E E+EIL +
Sbjct: 407 GYEVKEDIGVGSYS---VCKRCIHKATN-MEFAVKIIDKSK--RDPTE-----EIEILLR 455
Query: 475 I-ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQY 651
++P+II + + G V++ G+LLD I R E +A + ++Y
Sbjct: 456 YGQHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEY 515
Query: 652 LHSKNIAHRDLKCENIL 702
LH++ + HRDLK NIL
Sbjct: 516 LHAQGVVHRDLKPSNIL 532
>AL121914-5|CAI19324.1| 271|Homo sapiens aurora kinase A protein.
Length = 271
Score = 76.6 bits (180), Expect = 9e-14
Identities = 39/141 (27%), Positives = 74/141 (52%)
Frame = +1
Query: 304 IGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKIEN 483
IG+ +G+G + V+LA + LA K+ K + + +E RE+EI + + +
Sbjct: 135 IGRPLGKGKFGNVYLAR----EKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRH 190
Query: 484 PHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSK 663
P+I++++ RV++ + YA G + +++ E + + ++A+ L Y HSK
Sbjct: 191 PNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSK 250
Query: 664 NIAHRDLKCENILLSRRFNVK 726
+ HRD+K EN+LL +K
Sbjct: 251 RVIHRDIKPENLLLGSAGELK 271
>AD000092-1|AAB51171.1| 1237|Homo sapiens hypothetical human
serine-threonine protein kinase R31240_1 protein.
Length = 1237
Score = 76.2 bits (179), Expect = 1e-13
Identities = 43/141 (30%), Positives = 74/141 (52%), Gaps = 1/141 (0%)
Frame = +1
Query: 310 KKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAP-RDFLEKFFPRELEILTKIENP 486
K I G+Y V+L + D R A K +K+ R+ +++ F E +ILT ENP
Sbjct: 19 KLISNGAYGAVYLVRHRD----TRQRFAMKKINKQNLILRNQIQQAFV-ERDILTFAENP 73
Query: 487 HIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKN 666
++ + + + + M Y + GD +K G +P A+++F + L+YLH+
Sbjct: 74 FVVGMFCSFETRRHLCMVMEYVEGGDCATLLKNIGALPVEMARMYFAETVLALEYLHNYG 133
Query: 667 IAHRDLKCENILLSRRFNVKL 729
I HRDLK +N+L++ ++KL
Sbjct: 134 IVHRDLKPDNLLITSMGHIKL 154
>AB023190-1|BAA76817.1| 1583|Homo sapiens KIAA0973 protein protein.
Length = 1583
Score = 76.2 bits (179), Expect = 1e-13
Identities = 43/141 (30%), Positives = 74/141 (52%), Gaps = 1/141 (0%)
Frame = +1
Query: 310 KKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAP-RDFLEKFFPRELEILTKIENP 486
K I G+Y V+L + D R A K +K+ R+ +++ F E +ILT ENP
Sbjct: 391 KLISNGAYGAVYLVRHRD----TRQRFAMKKINKQNLILRNQIQQAFV-ERDILTFAENP 445
Query: 487 HIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKN 666
++ + + + + M Y + GD +K G +P A+++F + L+YLH+
Sbjct: 446 FVVGMFCSFETRRHLCMVMEYVEGGDCATLLKNIGALPVEMARMYFAETVLALEYLHNYG 505
Query: 667 IAHRDLKCENILLSRRFNVKL 729
I HRDLK +N+L++ ++KL
Sbjct: 506 IVHRDLKPDNLLITSMGHIKL 526
>Z98049-1|CAI20579.1| 733|Homo sapiens ribosomal protein S6 kinase,
90kDa, polypeptide 2 protein.
Length = 733
Score = 75.8 bits (178), Expect = 2e-13
Identities = 43/141 (30%), Positives = 73/141 (51%), Gaps = 1/141 (0%)
Frame = +1
Query: 310 KKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAP-RDFLEKFFPRELEILTKIENP 486
K +GQGSY V L GS +++ A K+ K RD + R+ IL ++ +P
Sbjct: 63 KVLGQGSYGKVFLVRKVKGSDAGQLY-AMKVLKKATLKVRDRVRSKMERD--ILAEVNHP 119
Query: 487 HIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKN 666
I+++H Q ++++ + + GDL + + + E K + ++A L +LHS
Sbjct: 120 FIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLG 179
Query: 667 IAHRDLKCENILLSRRFNVKL 729
I +RDLK ENILL ++K+
Sbjct: 180 IIYRDLKPENILLDEEGHIKI 200
Score = 62.9 bits (146), Expect = 1e-09
Identities = 48/137 (35%), Positives = 69/137 (50%), Gaps = 1/137 (0%)
Frame = +1
Query: 295 GYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTK 474
GY I + IG GSY+ + + C + + A KI DK K RD E E+EIL +
Sbjct: 414 GYEIKEDIGVGSYS---VCKRCVHKATDTEY-AVKIIDKSK--RDPSE-----EIEILLR 462
Query: 475 I-ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQY 651
++P+II + + G V++ M G+LLD I R E +A + + Y
Sbjct: 463 YGQHPNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDY 522
Query: 652 LHSKNIAHRDLKCENIL 702
LHS+ + HRDLK NIL
Sbjct: 523 LHSQGVVHRDLKPSNIL 539
>X85106-1|CAA59427.1| 733|Homo sapiens ribosomal S6 kinase protein.
Length = 733
Score = 75.8 bits (178), Expect = 2e-13
Identities = 43/141 (30%), Positives = 73/141 (51%), Gaps = 1/141 (0%)
Frame = +1
Query: 310 KKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAP-RDFLEKFFPRELEILTKIENP 486
K +GQGSY V L GS +++ A K+ K RD + R+ IL ++ +P
Sbjct: 63 KVLGQGSYGKVFLVRKVKGSDAGQLY-AMKVLKKATLKVRDRVRSKMERD--ILAEVNHP 119
Query: 487 HIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKN 666
I+++H Q ++++ + + GDL + + + E K + ++A L +LHS
Sbjct: 120 FIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLG 179
Query: 667 IAHRDLKCENILLSRRFNVKL 729
I +RDLK ENILL ++K+
Sbjct: 180 IIYRDLKPENILLDEEGHIKI 200
Score = 62.9 bits (146), Expect = 1e-09
Identities = 48/137 (35%), Positives = 69/137 (50%), Gaps = 1/137 (0%)
Frame = +1
Query: 295 GYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTK 474
GY I + IG GSY+ + + C + + A KI DK K RD E E+EIL +
Sbjct: 414 GYEIKEDIGVGSYS---VCKRCVHKATDTEY-AVKIIDKSK--RDPSE-----EIEILLR 462
Query: 475 I-ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQY 651
++P+II + + G V++ M G+LLD I R E +A + + Y
Sbjct: 463 YGQHPNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDY 522
Query: 652 LHSKNIAHRDLKCENIL 702
LHS+ + HRDLK NIL
Sbjct: 523 LHSQGVVHRDLKPSNIL 539
>L33881-1|AAB17011.1| 587|Homo sapiens protein kinase C iota
protein.
Length = 587
Score = 75.8 bits (178), Expect = 2e-13
Identities = 50/165 (30%), Positives = 83/165 (50%), Gaps = 1/165 (0%)
Frame = +1
Query: 238 SMADRLSPRSSEVNALEQRGYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEK 417
+M R S ++S L+ L + IG+GSYA V L R++ A K+ KE
Sbjct: 227 AMNTRESGKASSSLGLQDFDLL--RVIGRGSYAKVLLVRL---KKTDRIY-AMKVVKKEL 280
Query: 418 APRDFLEKFFPRELEILTKIEN-PHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGV 594
D + E + + N P ++ +HS Q R+F + Y + GDL+ ++R
Sbjct: 281 VNDDEDIDWVQTEKHVFEQASNHPFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQRK 340
Query: 595 VPENQAKLWFRQMASGLQYLHSKNIAHRDLKCENILLSRRFNVKL 729
+PE A+ + +++ L YLH + I +RDLK +N+LL ++KL
Sbjct: 341 LPEEHARFYSAEISLALNYLHERGIIYRDLKLDNVLLDSEGHIKL 385
>L20321-1|AAA36658.1| 841|Homo sapiens protein serine/threonine
kinase protein.
Length = 841
Score = 75.8 bits (178), Expect = 2e-13
Identities = 46/148 (31%), Positives = 85/148 (57%), Gaps = 4/148 (2%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYC-DGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTK 474
Y + +G+GSY V L ++ DG + ++ K+ + + R+ + +E ++L++
Sbjct: 6 YCYLRVVGKGSYGEVTLVKHRRDG----KQYVIKKLNLRNASSRE--RRAAEQEAQLLSQ 59
Query: 475 IENPHIIQVHSILQRGPRV-FIFMRYADNGDLLDFIK--RNGVVPENQAKLWFRQMASGL 645
+++P+I+ + G + +I M + + GDL +K + ++PENQ WF Q+A L
Sbjct: 60 LKHPNIVTYKESWEGGDGLLYIVMGFCEGGDLYRKLKEQKGQLLPENQVVEWFVQIAMAL 119
Query: 646 QYLHSKNIAHRDLKCENILLSRRFNVKL 729
QYLH K+I HRDLK +N+ L+R +K+
Sbjct: 120 QYLHEKHILHRDLKTQNVFLTRTNIIKV 147
>L18964-1|AAA60171.1| 587|Homo sapiens protein kinase C iota
protein.
Length = 587
Score = 75.8 bits (178), Expect = 2e-13
Identities = 50/165 (30%), Positives = 83/165 (50%), Gaps = 1/165 (0%)
Frame = +1
Query: 238 SMADRLSPRSSEVNALEQRGYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEK 417
+M R S ++S L+ L + IG+GSYA V L R++ A K+ KE
Sbjct: 227 AMNTRESGKASSSLGLQDFDLL--RVIGRGSYAKVLLVRL---KKTDRIY-AMKVVKKEL 280
Query: 418 APRDFLEKFFPRELEILTKIEN-PHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGV 594
D + E + + N P ++ +HS Q R+F + Y + GDL+ ++R
Sbjct: 281 VNDDEDIDWVQTEKHVFEQASNHPFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQRK 340
Query: 595 VPENQAKLWFRQMASGLQYLHSKNIAHRDLKCENILLSRRFNVKL 729
+PE A+ + +++ L YLH + I +RDLK +N+LL ++KL
Sbjct: 341 LPEEHARFYSAEISLALNYLHERGIIYRDLKLDNVLLDSEGHIKL 385
>L07598-1|AAC82496.1| 540|Homo sapiens ribosomal protein S6 kinase
2 protein.
Length = 540
Score = 75.8 bits (178), Expect = 2e-13
Identities = 43/141 (30%), Positives = 73/141 (51%), Gaps = 1/141 (0%)
Frame = +1
Query: 310 KKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAP-RDFLEKFFPRELEILTKIENP 486
K +GQGSY V L GS +++ A K+ K RD + R+ IL ++ +P
Sbjct: 64 KVLGQGSYGKVFLVRKVKGSDAGQLY-AMKVLKKATLKVRDRVRSKMERD--ILAEVNHP 120
Query: 487 HIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKN 666
I+++H Q ++++ + + GDL + + + E K + ++A L +LHS
Sbjct: 121 FIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLG 180
Query: 667 IAHRDLKCENILLSRRFNVKL 729
I +RDLK ENILL ++K+
Sbjct: 181 IIYRDLKPENILLDEEGHIKI 201
Score = 60.1 bits (139), Expect = 8e-09
Identities = 47/137 (34%), Positives = 68/137 (49%), Gaps = 1/137 (0%)
Frame = +1
Query: 295 GYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTK 474
GY I + IG GSY+ + + C + + A KI K K RD E E+EIL +
Sbjct: 415 GYEIKEDIGVGSYS---VCKRCVHKATDTEY-AVKIIGKSK--RDPSE-----EIEILLR 463
Query: 475 I-ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQY 651
++P+II + + G V++ M G+LLD I R E +A + + Y
Sbjct: 464 YGQHPNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDY 523
Query: 652 LHSKNIAHRDLKCENIL 702
LHS+ + HRDLK NIL
Sbjct: 524 LHSQGVVHRDLKPSNIL 540
>BC063044-1|AAH63044.1| 781|Homo sapiens NEK4 protein protein.
Length = 781
Score = 75.8 bits (178), Expect = 2e-13
Identities = 46/148 (31%), Positives = 85/148 (57%), Gaps = 4/148 (2%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYC-DGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTK 474
Y + +G+GSY V L ++ DG + ++ K+ + + R+ + +E ++L++
Sbjct: 6 YCYLRVVGKGSYGEVTLVKHRRDG----KQYVIKKLNLRNASSRE--RRAAEQEAQLLSQ 59
Query: 475 IENPHIIQVHSILQRGPRV-FIFMRYADNGDLLDFIK--RNGVVPENQAKLWFRQMASGL 645
+++P+I+ + G + +I M + + GDL +K + ++PENQ WF Q+A L
Sbjct: 60 LKHPNIVTYKESWEGGDGLLYIVMGFCEGGDLYRKLKEQKGQLLPENQVVEWFVQIAMAL 119
Query: 646 QYLHSKNIAHRDLKCENILLSRRFNVKL 729
QYLH K+I HRDLK +N+ L+R +K+
Sbjct: 120 QYLHEKHILHRDLKTQNVFLTRTNIIKV 147
>BC048980-1|AAH48980.1| 574|Homo sapiens protein kinase,
AMP-activated, alpha 1 catalytic subunit protein.
Length = 574
Score = 75.8 bits (178), Expect = 2e-13
Identities = 47/160 (29%), Positives = 84/160 (52%), Gaps = 15/160 (9%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKI 477
Y++G +G G++ V + ++ + + K +A KI +++K + RE++ L
Sbjct: 27 YILGDTLGVGTFGKVKVGKH-ELTGHK---VAVKILNRQKIRSLDVVGKIRREIQNLKLF 82
Query: 478 ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGV---VP------------ENQA 612
+PHII+++ ++ +F+ M Y G+L D+I +NG VP E ++
Sbjct: 83 RHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRKSDVPGVVKTGSTKELDEKES 142
Query: 613 KLWFRQMASGLQYLHSKNIAHRDLKCENILLSRRFNVKLA 732
+ F+Q+ SG+ Y H + HRDLK EN+LL N K+A
Sbjct: 143 RRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIA 182
>BC022016-1|AAH22016.3| 587|Homo sapiens protein kinase C, iota
protein.
Length = 587
Score = 75.8 bits (178), Expect = 2e-13
Identities = 50/165 (30%), Positives = 83/165 (50%), Gaps = 1/165 (0%)
Frame = +1
Query: 238 SMADRLSPRSSEVNALEQRGYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEK 417
+M R S ++S L+ L + IG+GSYA V L R++ A K+ KE
Sbjct: 227 AMNTRESGKASSSLGLQDFDLL--RVIGRGSYAKVLLVRL---KKTDRIY-AMKVVKKEL 280
Query: 418 APRDFLEKFFPRELEILTKIEN-PHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGV 594
D + E + + N P ++ +HS Q R+F + Y + GDL+ ++R
Sbjct: 281 VNDDEDIDWVQTEKHVFEQASNHPFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQRK 340
Query: 595 VPENQAKLWFRQMASGLQYLHSKNIAHRDLKCENILLSRRFNVKL 729
+PE A+ + +++ L YLH + I +RDLK +N+LL ++KL
Sbjct: 341 LPEEHARFYSAEISLALNYLHERGIIYRDLKLDNVLLDSEGHIKL 385
>BC015515-1|AAH15515.1| 451|Homo sapiens Unknown (protein for
IMAGE:3913546) protein.
Length = 451
Score = 75.8 bits (178), Expect = 2e-13
Identities = 46/148 (31%), Positives = 85/148 (57%), Gaps = 4/148 (2%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYC-DGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTK 474
Y + +G+GSY V L ++ DG + ++ K+ + + R+ + +E ++L++
Sbjct: 6 YCYLRVVGKGSYGEVTLVKHRRDG----KQYVIKKLNLRNASSRE--RRAAEQEAQLLSQ 59
Query: 475 IENPHIIQVHSILQRGPRV-FIFMRYADNGDLLDFIK--RNGVVPENQAKLWFRQMASGL 645
+++P+I+ + G + +I M + + GDL +K + ++PENQ WF Q+A L
Sbjct: 60 LKHPNIVTYKESWEGGDGLLYIVMGFCEGGDLYRKLKEQKGQLLPENQVVEWFVQIAMAL 119
Query: 646 QYLHSKNIAHRDLKCENILLSRRFNVKL 729
QYLH K+I HRDLK +N+ L+R +K+
Sbjct: 120 QYLHEKHILHRDLKTQNVFLTRTNIIKV 147
>BC002363-1|AAH02363.1| 733|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 2 protein.
Length = 733
Score = 75.8 bits (178), Expect = 2e-13
Identities = 43/141 (30%), Positives = 73/141 (51%), Gaps = 1/141 (0%)
Frame = +1
Query: 310 KKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAP-RDFLEKFFPRELEILTKIENP 486
K +GQGSY V L GS +++ A K+ K RD + R+ IL ++ +P
Sbjct: 63 KVLGQGSYGKVFLVRKVKGSDAGQLY-AMKVLKKATLKVRDRVRSKMERD--ILAEVNHP 119
Query: 487 HIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKN 666
I+++H Q ++++ + + GDL + + + E K + ++A L +LHS
Sbjct: 120 FIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLG 179
Query: 667 IAHRDLKCENILLSRRFNVKL 729
I +RDLK ENILL ++K+
Sbjct: 180 IIYRDLKPENILLDEEGHIKI 200
Score = 62.9 bits (146), Expect = 1e-09
Identities = 48/137 (35%), Positives = 69/137 (50%), Gaps = 1/137 (0%)
Frame = +1
Query: 295 GYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTK 474
GY I + IG GSY+ + + C + + A KI DK K RD E E+EIL +
Sbjct: 414 GYEIKEDIGVGSYS---VCKRCVHKATDTEY-AVKIIDKSK--RDPSE-----EIEILLR 462
Query: 475 I-ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQY 651
++P+II + + G V++ M G+LLD I R E +A + + Y
Sbjct: 463 YGQHPNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDY 522
Query: 652 LHSKNIAHRDLKCENIL 702
LHS+ + HRDLK NIL
Sbjct: 523 LHSQGVVHRDLKPSNIL 539
>AL022069-2|CAI19651.1| 733|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 2 protein.
Length = 733
Score = 75.8 bits (178), Expect = 2e-13
Identities = 43/141 (30%), Positives = 73/141 (51%), Gaps = 1/141 (0%)
Frame = +1
Query: 310 KKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAP-RDFLEKFFPRELEILTKIENP 486
K +GQGSY V L GS +++ A K+ K RD + R+ IL ++ +P
Sbjct: 63 KVLGQGSYGKVFLVRKVKGSDAGQLY-AMKVLKKATLKVRDRVRSKMERD--ILAEVNHP 119
Query: 487 HIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKN 666
I+++H Q ++++ + + GDL + + + E K + ++A L +LHS
Sbjct: 120 FIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLG 179
Query: 667 IAHRDLKCENILLSRRFNVKL 729
I +RDLK ENILL ++K+
Sbjct: 180 IIYRDLKPENILLDEEGHIKI 200
Score = 62.9 bits (146), Expect = 1e-09
Identities = 48/137 (35%), Positives = 69/137 (50%), Gaps = 1/137 (0%)
Frame = +1
Query: 295 GYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTK 474
GY I + IG GSY+ + + C + + A KI DK K RD E E+EIL +
Sbjct: 414 GYEIKEDIGVGSYS---VCKRCVHKATDTEY-AVKIIDKSK--RDPSE-----EIEILLR 462
Query: 475 I-ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQY 651
++P+II + + G V++ M G+LLD I R E +A + + Y
Sbjct: 463 YGQHPNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDY 522
Query: 652 LHSKNIAHRDLKCENIL 702
LHS+ + HRDLK NIL
Sbjct: 523 LHSQGVVHRDLKPSNIL 539
>AB209116-1|BAD92353.1| 806|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 2 isoform b variant protein.
Length = 806
Score = 75.8 bits (178), Expect = 2e-13
Identities = 43/141 (30%), Positives = 73/141 (51%), Gaps = 1/141 (0%)
Frame = +1
Query: 310 KKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAP-RDFLEKFFPRELEILTKIENP 486
K +GQGSY V L GS +++ A K+ K RD + R+ IL ++ +P
Sbjct: 136 KVLGQGSYGKVFLVRKVKGSDAGQLY-AMKVLKKATLKVRDRVRSKMERD--ILAEVNHP 192
Query: 487 HIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKN 666
I+++H Q ++++ + + GDL + + + E K + ++A L +LHS
Sbjct: 193 FIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLG 252
Query: 667 IAHRDLKCENILLSRRFNVKL 729
I +RDLK ENILL ++K+
Sbjct: 253 IIYRDLKPENILLDEEGHIKI 273
Score = 62.9 bits (146), Expect = 1e-09
Identities = 48/137 (35%), Positives = 69/137 (50%), Gaps = 1/137 (0%)
Frame = +1
Query: 295 GYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTK 474
GY I + IG GSY+ + + C + + A KI DK K RD E E+EIL +
Sbjct: 487 GYEIKEDIGVGSYS---VCKRCVHKATDTEY-AVKIIDKSK--RDPSE-----EIEILLR 535
Query: 475 I-ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQY 651
++P+II + + G V++ M G+LLD I R E +A + + Y
Sbjct: 536 YGQHPNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDY 595
Query: 652 LHSKNIAHRDLKCENIL 702
LHS+ + HRDLK NIL
Sbjct: 596 LHSQGVVHRDLKPSNIL 612
>CR542227-1|CAG47023.1| 431|Homo sapiens STK24 protein.
Length = 431
Score = 75.4 bits (177), Expect = 2e-13
Identities = 47/141 (33%), Positives = 77/141 (54%)
Frame = +1
Query: 310 KKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKIENPH 489
+KIG+GS+ V D + K + A KI D E+A D +E +E+ +L++ ++P+
Sbjct: 28 EKIGKGSFGEVFKG--IDNRTQKVV--AIKIIDLEEA-EDEIEDI-QQEITVLSQCDSPY 81
Query: 490 IIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKNI 669
+ + + + +++I M Y G LD ++ G + E Q R++ GL YLHS+
Sbjct: 82 VTKYYGSYLKDTKLWIIMEYLGGGSALDLLEP-GPLDETQIATILREILKGLDYLHSEKK 140
Query: 670 AHRDLKCENILLSRRFNVKLA 732
HRD+K N+LLS VKLA
Sbjct: 141 IHRDIKAANVLLSEHGEVKLA 161
>BT019619-1|AAV38425.1| 431|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 431
Score = 75.4 bits (177), Expect = 2e-13
Identities = 47/141 (33%), Positives = 77/141 (54%)
Frame = +1
Query: 310 KKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKIENPH 489
+KIG+GS+ V D + K + A KI D E+A D +E +E+ +L++ ++P+
Sbjct: 28 EKIGKGSFGEVFKG--IDNRTQKVV--AIKIIDLEEA-EDEIEDI-QQEITVLSQCDSPY 81
Query: 490 IIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKNI 669
+ + + + +++I M Y G LD ++ G + E Q R++ GL YLHS+
Sbjct: 82 VTKYYGSYLKDTKLWIIMEYLGGGSALDLLEP-GPLDETQIATILREILKGLDYLHSEKK 140
Query: 670 AHRDLKCENILLSRRFNVKLA 732
HRD+K N+LLS VKLA
Sbjct: 141 IHRDIKAANVLLSEHGEVKLA 161
>BC096303-1|AAH96303.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 75.4 bits (177), Expect = 2e-13
Identities = 43/141 (30%), Positives = 75/141 (53%), Gaps = 1/141 (0%)
Frame = +1
Query: 310 KKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAP-RDFLEKFFPRELEILTKIENP 486
K +GQGS+ V L + GS ++++ A K+ K RD + R+ IL ++ +P
Sbjct: 72 KVLGQGSFGKVFLVKKILGSDARQLY-AMKVLKKATLKVRDRVRTKMERD--ILVEVNHP 128
Query: 487 HIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKN 666
I+++H Q ++++ + + GDL + + + E K + ++A L +LHS
Sbjct: 129 FIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLG 188
Query: 667 IAHRDLKCENILLSRRFNVKL 729
I +RDLK ENILL ++KL
Sbjct: 189 IIYRDLKPENILLDEEGHIKL 209
Score = 64.9 bits (151), Expect = 3e-10
Identities = 46/137 (33%), Positives = 69/137 (50%), Gaps = 1/137 (0%)
Frame = +1
Query: 295 GYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTK 474
GY + + IG GSY+ + + C + M A KI DK K RD E E+EIL +
Sbjct: 421 GYEVKEDIGVGSYS---VCKRCIHKATN-MEFAVKIIDKSK--RDPTE-----EIEILLR 469
Query: 475 I-ENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQY 651
++P+II + + G V++ G+LLD I R E +A + ++Y
Sbjct: 470 YGQHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEY 529
Query: 652 LHSKNIAHRDLKCENIL 702
LH++ + HRDLK NIL
Sbjct: 530 LHAQGVVHRDLKPSNIL 546
>BC065378-1|AAH65378.1| 431|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 431
Score = 75.4 bits (177), Expect = 2e-13
Identities = 47/141 (33%), Positives = 77/141 (54%)
Frame = +1
Query: 310 KKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKIENPH 489
+KIG+GS+ V D + K + A KI D E+A D +E +E+ +L++ ++P+
Sbjct: 28 EKIGKGSFGEVFKG--IDNRTQKVV--AIKIIDLEEA-EDEIEDI-QQEITVLSQCDSPY 81
Query: 490 IIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKNI 669
+ + + + +++I M Y G LD ++ G + E Q R++ GL YLHS+
Sbjct: 82 VTKYYGSYLKDTKLWIIMEYLGGGSALDLLEP-GPLDETQIATILREILKGLDYLHSEKK 140
Query: 670 AHRDLKCENILLSRRFNVKLA 732
HRD+K N+LLS VKLA
Sbjct: 141 IHRDIKAANVLLSEHGEVKLA 161
>BC035578-1|AAH35578.1| 431|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 431
Score = 75.4 bits (177), Expect = 2e-13
Identities = 47/141 (33%), Positives = 77/141 (54%)
Frame = +1
Query: 310 KKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKIENPH 489
+KIG+GS+ V D + K + A KI D E+A D +E +E+ +L++ ++P+
Sbjct: 28 EKIGKGSFGEVFKG--IDNRTQKVV--AIKIIDLEEA-EDEIEDI-QQEITVLSQCDSPY 81
Query: 490 IIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKNI 669
+ + + + +++I M Y G LD ++ G + E Q R++ GL YLHS+
Sbjct: 82 VTKYYGSYLKDTKLWIIMEYLGGGSALDLLEP-GPLDETQIATILREILKGLDYLHSEKK 140
Query: 670 AHRDLKCENILLSRRFNVKLA 732
HRD+K N+LLS VKLA
Sbjct: 141 IHRDIKAANVLLSEHGEVKLA 161
>AL356423-3|CAI13115.1| 431|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 431
Score = 75.4 bits (177), Expect = 2e-13
Identities = 47/141 (33%), Positives = 77/141 (54%)
Frame = +1
Query: 310 KKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKIENPH 489
+KIG+GS+ V D + K + A KI D E+A D +E +E+ +L++ ++P+
Sbjct: 28 EKIGKGSFGEVFKG--IDNRTQKVV--AIKIIDLEEA-EDEIEDI-QQEITVLSQCDSPY 81
Query: 490 IIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKNI 669
+ + + + +++I M Y G LD ++ G + E Q R++ GL YLHS+
Sbjct: 82 VTKYYGSYLKDTKLWIIMEYLGGGSALDLLEP-GPLDETQIATILREILKGLDYLHSEKK 140
Query: 670 AHRDLKCENILLSRRFNVKLA 732
HRD+K N+LLS VKLA
Sbjct: 141 IHRDIKAANVLLSEHGEVKLA 161
>AL356423-2|CAI13114.1| 443|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 443
Score = 75.4 bits (177), Expect = 2e-13
Identities = 47/141 (33%), Positives = 77/141 (54%)
Frame = +1
Query: 310 KKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKIENPH 489
+KIG+GS+ V D + K + A KI D E+A D +E +E+ +L++ ++P+
Sbjct: 40 EKIGKGSFGEVFKG--IDNRTQKVV--AIKIIDLEEA-EDEIEDI-QQEITVLSQCDSPY 93
Query: 490 IIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKNI 669
+ + + + +++I M Y G LD ++ G + E Q R++ GL YLHS+
Sbjct: 94 VTKYYGSYLKDTKLWIIMEYLGGGSALDLLEP-GPLDETQIATILREILKGLDYLHSEKK 152
Query: 670 AHRDLKCENILLSRRFNVKLA 732
HRD+K N+LLS VKLA
Sbjct: 153 IHRDIKAANVLLSEHGEVKLA 173
>AL137249-7|CAI39457.1| 431|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 431
Score = 75.4 bits (177), Expect = 2e-13
Identities = 47/141 (33%), Positives = 77/141 (54%)
Frame = +1
Query: 310 KKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKIENPH 489
+KIG+GS+ V D + K + A KI D E+A D +E +E+ +L++ ++P+
Sbjct: 28 EKIGKGSFGEVFKG--IDNRTQKVV--AIKIIDLEEA-EDEIEDI-QQEITVLSQCDSPY 81
Query: 490 IIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKNI 669
+ + + + +++I M Y G LD ++ G + E Q R++ GL YLHS+
Sbjct: 82 VTKYYGSYLKDTKLWIIMEYLGGGSALDLLEP-GPLDETQIATILREILKGLDYLHSEKK 140
Query: 670 AHRDLKCENILLSRRFNVKLA 732
HRD+K N+LLS VKLA
Sbjct: 141 IHRDIKAANVLLSEHGEVKLA 161
>AL137249-3|CAI39453.1| 443|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 443
Score = 75.4 bits (177), Expect = 2e-13
Identities = 47/141 (33%), Positives = 77/141 (54%)
Frame = +1
Query: 310 KKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKIENPH 489
+KIG+GS+ V D + K + A KI D E+A D +E +E+ +L++ ++P+
Sbjct: 40 EKIGKGSFGEVFKG--IDNRTQKVV--AIKIIDLEEA-EDEIEDI-QQEITVLSQCDSPY 93
Query: 490 IIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKNI 669
+ + + + +++I M Y G LD ++ G + E Q R++ GL YLHS+
Sbjct: 94 VTKYYGSYLKDTKLWIIMEYLGGGSALDLLEP-GPLDETQIATILREILKGLDYLHSEKK 152
Query: 670 AHRDLKCENILLSRRFNVKLA 732
HRD+K N+LLS VKLA
Sbjct: 153 IHRDIKAANVLLSEHGEVKLA 173
>AF083420-1|AAD42039.1| 443|Homo sapiens brain-specific STE20-like
protein kinase 3 protein.
Length = 443
Score = 75.4 bits (177), Expect = 2e-13
Identities = 47/141 (33%), Positives = 77/141 (54%)
Frame = +1
Query: 310 KKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKIENPH 489
+KIG+GS+ V D + K + A KI D E+A D +E +E+ +L++ ++P+
Sbjct: 40 EKIGKGSFGEVFKG--IDNRTQKVV--AIKIIDLEEA-EDEIEDI-QQEITVLSQCDSPY 93
Query: 490 IIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKNI 669
+ + + + +++I M Y G LD ++ G + E Q R++ GL YLHS+
Sbjct: 94 VTKYYGSYLKDTKLWIIMEYLGGGSALDLLEP-GPLDETQIATILREILKGLDYLHSEKK 152
Query: 670 AHRDLKCENILLSRRFNVKLA 732
HRD+K N+LLS VKLA
Sbjct: 153 IHRDIKAANVLLSEHGEVKLA 173
>AF024636-1|AAB82560.1| 431|Homo sapiens STE20-like kinase 3
protein.
Length = 431
Score = 75.4 bits (177), Expect = 2e-13
Identities = 47/141 (33%), Positives = 77/141 (54%)
Frame = +1
Query: 310 KKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKIENPH 489
+KIG+GS+ V D + K + A KI D E+A D +E +E+ +L++ ++P+
Sbjct: 28 EKIGKGSFGEVFKG--IDNRTQKVV--AIKIIDLEEA-EDEIEDI-QQEITVLSQCDSPY 81
Query: 490 IIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKNI 669
+ + + + +++I M Y G LD ++ G + E Q R++ GL YLHS+
Sbjct: 82 VTKYYGSYLKDTKLWIIMEYLGGGSALDLLEP-GPLDETQIATILREILKGLDYLHSEKK 140
Query: 670 AHRDLKCENILLSRRFNVKLA 732
HRD+K N+LLS VKLA
Sbjct: 141 IHRDIKAANVLLSEHGEVKLA 161
>AB183427-1|BAF73615.1| 619|Homo sapiens maternal embryonic leucine
zipper kinase v2 protein.
Length = 619
Score = 75.4 bits (177), Expect = 2e-13
Identities = 32/92 (34%), Positives = 55/92 (59%)
Frame = +1
Query: 454 ELEILTKIENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQM 633
E+E L + + HI Q++ +L+ ++F+ + Y G+L D+I + E + ++ FRQ+
Sbjct: 25 EIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQI 84
Query: 634 ASGLQYLHSKNIAHRDLKCENILLSRRFNVKL 729
S + Y+HS+ AHRDLK EN+L +KL
Sbjct: 85 VSAVAYVHSQGYAHRDLKPENLLFDEYHKLKL 116
>Z84486-1|CAI21678.1| 526|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 526
Score = 74.9 bits (176), Expect = 3e-13
Identities = 44/141 (31%), Positives = 76/141 (53%), Gaps = 1/141 (0%)
Frame = +1
Query: 310 KKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTK-IENP 486
K IG+GS+ V LA + + + A K+ K+ + EK E +L K +++P
Sbjct: 197 KVIGKGSFGKVLLARH----KAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHP 252
Query: 487 HIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKN 666
++ +H Q +++ + Y + G+L ++R E +A+ + ++AS L YLHS N
Sbjct: 253 FLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLN 312
Query: 667 IAHRDLKCENILLSRRFNVKL 729
I +RDLK ENILL + ++ L
Sbjct: 313 IVYRDLKPENILLDSQGHIVL 333
>Y10032-1|CAA71138.1| 431|Homo sapiens serine/threonine protein
kinase protein.
Length = 431
Score = 74.9 bits (176), Expect = 3e-13
Identities = 44/141 (31%), Positives = 76/141 (53%), Gaps = 1/141 (0%)
Frame = +1
Query: 310 KKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTK-IENP 486
K IG+GS+ V LA + + + A K+ K+ + EK E +L K +++P
Sbjct: 102 KVIGKGSFGKVLLARH----KAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHP 157
Query: 487 HIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKN 666
++ +H Q +++ + Y + G+L ++R E +A+ + ++AS L YLHS N
Sbjct: 158 FLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLN 217
Query: 667 IAHRDLKCENILLSRRFNVKL 729
I +RDLK ENILL + ++ L
Sbjct: 218 IVYRDLKPENILLDSQGHIVL 238
>X76104-1|CAA53712.1| 1431|Homo sapiens DAP-kinase protein.
Length = 1431
Score = 74.9 bits (176), Expect = 3e-13
Identities = 44/142 (30%), Positives = 73/142 (51%), Gaps = 3/142 (2%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAP---RDFLEKFFPRELEIL 468
Y G+++G G +A V + C S + A K K + R + RE+ IL
Sbjct: 13 YDTGEELGSGQFAVV---KKCREKSTG-LQYAAKFIKKRRTKSSRRGVSREDIEREVSIL 68
Query: 469 TKIENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQ 648
+I++P++I +H + + V + + G+L DF+ + E +A + +Q+ +G+
Sbjct: 69 KEIQHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQILNGVY 128
Query: 649 YLHSKNIAHRDLKCENILLSRR 714
YLHS IAH DLK ENI+L R
Sbjct: 129 YLHSLQIAHFDLKPENIMLLDR 150
>EF560744-1|ABQ59054.1| 841|Homo sapiens NEK4 protein protein.
Length = 841
Score = 74.9 bits (176), Expect = 3e-13
Identities = 46/148 (31%), Positives = 84/148 (56%), Gaps = 4/148 (2%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYC-DGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTK 474
Y + +G+GSY V L ++ DG + ++ K+ + + R+ + +E ++L++
Sbjct: 6 YCYLRVVGKGSYGEVTLVKHRRDG----KQYVIKKLNLRNASSRE--RRAAEQEAQLLSQ 59
Query: 475 IENPHIIQVHSILQRGPRV-FIFMRYADNGDLLDFIK--RNGVVPENQAKLWFRQMASGL 645
+++P I+ + G + +I M + + GDL +K + ++PENQ WF Q+A L
Sbjct: 60 LKHPDIVTYKESWEGGDGLLYIVMGFCEGGDLYRKLKEQKGQLLPENQVVEWFVQIAMAL 119
Query: 646 QYLHSKNIAHRDLKCENILLSRRFNVKL 729
QYLH K+I HRDLK +N+ L+R +K+
Sbjct: 120 QYLHEKHILHRDLKTQNVFLTRTNIIKV 147
>DQ436495-1|ABD96827.1| 1430|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1430
Score = 74.9 bits (176), Expect = 3e-13
Identities = 44/142 (30%), Positives = 73/142 (51%), Gaps = 3/142 (2%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAP---RDFLEKFFPRELEIL 468
Y G+++G G +A V + C S + A K K + R + RE+ IL
Sbjct: 13 YDTGEELGSGQFAVV---KKCREKSTG-LQYAAKFIKKRRTKSSRRGVSREDIEREVSIL 68
Query: 469 TKIENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQ 648
+I++P++I +H + + V + + G+L DF+ + E +A + +Q+ +G+
Sbjct: 69 KEIQHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQILNGVY 128
Query: 649 YLHSKNIAHRDLKCENILLSRR 714
YLHS IAH DLK ENI+L R
Sbjct: 129 YLHSLQIAHFDLKPENIMLLDR 150
>BT006935-1|AAP35581.1| 367|Homo sapiens death-associated protein
kinase 1 protein.
Length = 367
Score = 74.9 bits (176), Expect = 3e-13
Identities = 44/142 (30%), Positives = 73/142 (51%), Gaps = 3/142 (2%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAP---RDFLEKFFPRELEIL 468
Y G+++G G +A V + C S + A K K + R + RE+ IL
Sbjct: 13 YDTGEELGSGQFAVV---KKCREKSTG-LQYAAKFIKKRRTKSSRRGVSREDIEREVSIL 68
Query: 469 TKIENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQ 648
+I++P++I +H + + V + + G+L DF+ + E +A + +Q+ +G+
Sbjct: 69 KEIQHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQILNGVY 128
Query: 649 YLHSKNIAHRDLKCENILLSRR 714
YLHS IAH DLK ENI+L R
Sbjct: 129 YLHSLQIAHFDLKPENIMLLDR 150
>BC113660-1|AAI13661.1| 1430|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1430
Score = 74.9 bits (176), Expect = 3e-13
Identities = 44/142 (30%), Positives = 73/142 (51%), Gaps = 3/142 (2%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAP---RDFLEKFFPRELEIL 468
Y G+++G G +A V + C S + A K K + R + RE+ IL
Sbjct: 13 YDTGEELGSGQFAVV---KKCREKSTG-LQYAAKFIKKRRTKSSRRGVSREDIEREVSIL 68
Query: 469 TKIENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQ 648
+I++P++I +H + + V + + G+L DF+ + E +A + +Q+ +G+
Sbjct: 69 KEIQHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQILNGVY 128
Query: 649 YLHSKNIAHRDLKCENILLSRR 714
YLHS IAH DLK ENI+L R
Sbjct: 129 YLHSLQIAHFDLKPENIMLLDR 150
>BC001263-1|AAH01263.1| 431|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 431
Score = 74.9 bits (176), Expect = 3e-13
Identities = 44/141 (31%), Positives = 76/141 (53%), Gaps = 1/141 (0%)
Frame = +1
Query: 310 KKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTK-IENP 486
K IG+GS+ V LA + + + A K+ K+ + EK E +L K +++P
Sbjct: 102 KVIGKGSFGKVLLARH----KAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHP 157
Query: 487 HIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKN 666
++ +H Q +++ + Y + G+L ++R E +A+ + ++AS L YLHS N
Sbjct: 158 FLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLN 217
Query: 667 IAHRDLKCENILLSRRFNVKL 729
I +RDLK ENILL + ++ L
Sbjct: 218 IVYRDLKPENILLDSQGHIVL 238
>AL591852-1|CAH71696.1| 1455|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1455
Score = 74.9 bits (176), Expect = 3e-13
Identities = 44/142 (30%), Positives = 73/142 (51%), Gaps = 3/142 (2%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAP---RDFLEKFFPRELEIL 468
Y G+++G G +A V + C S + A K K + R + RE+ IL
Sbjct: 13 YDTGEELGSGQFAVV---KKCREKSTG-LQYAAKFIKKRRTKSSRRGVSREDIEREVSIL 68
Query: 469 TKIENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQ 648
+I++P++I +H + + V + + G+L DF+ + E +A + +Q+ +G+
Sbjct: 69 KEIQHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQILNGVY 128
Query: 649 YLHSKNIAHRDLKCENILLSRR 714
YLHS IAH DLK ENI+L R
Sbjct: 129 YLHSLQIAHFDLKPENIMLLDR 150
>AL355881-2|CAH72579.1| 526|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 526
Score = 74.9 bits (176), Expect = 3e-13
Identities = 44/141 (31%), Positives = 76/141 (53%), Gaps = 1/141 (0%)
Frame = +1
Query: 310 KKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTK-IENP 486
K IG+GS+ V LA + + + A K+ K+ + EK E +L K +++P
Sbjct: 197 KVIGKGSFGKVLLARH----KAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHP 252
Query: 487 HIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKN 666
++ +H Q +++ + Y + G+L ++R E +A+ + ++AS L YLHS N
Sbjct: 253 FLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLN 312
Query: 667 IAHRDLKCENILLSRRFNVKL 729
I +RDLK ENILL + ++ L
Sbjct: 313 IVYRDLKPENILLDSQGHIVL 333
>AL161787-1|CAH73544.1| 1455|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1455
Score = 74.9 bits (176), Expect = 3e-13
Identities = 44/142 (30%), Positives = 73/142 (51%), Gaps = 3/142 (2%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAP---RDFLEKFFPRELEIL 468
Y G+++G G +A V + C S + A K K + R + RE+ IL
Sbjct: 13 YDTGEELGSGQFAVV---KKCREKSTG-LQYAAKFIKKRRTKSSRRGVSREDIEREVSIL 68
Query: 469 TKIENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQ 648
+I++P++I +H + + V + + G+L DF+ + E +A + +Q+ +G+
Sbjct: 69 KEIQHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQILNGVY 128
Query: 649 YLHSKNIAHRDLKCENILLSRR 714
YLHS IAH DLK ENI+L R
Sbjct: 129 YLHSLQIAHFDLKPENIMLLDR 150
>AL160279-1|CAI16306.1| 1455|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1455
Score = 74.9 bits (176), Expect = 3e-13
Identities = 44/142 (30%), Positives = 73/142 (51%), Gaps = 3/142 (2%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAP---RDFLEKFFPRELEIL 468
Y G+++G G +A V + C S + A K K + R + RE+ IL
Sbjct: 13 YDTGEELGSGQFAVV---KKCREKSTG-LQYAAKFIKKRRTKSSRRGVSREDIEREVSIL 68
Query: 469 TKIENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQ 648
+I++P++I +H + + V + + G+L DF+ + E +A + +Q+ +G+
Sbjct: 69 KEIQHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQILNGVY 128
Query: 649 YLHSKNIAHRDLKCENILLSRR 714
YLHS IAH DLK ENI+L R
Sbjct: 129 YLHSLQIAHFDLKPENIMLLDR 150
>AL135839-4|CAI19721.1| 526|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 526
Score = 74.9 bits (176), Expect = 3e-13
Identities = 44/141 (31%), Positives = 76/141 (53%), Gaps = 1/141 (0%)
Frame = +1
Query: 310 KKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTK-IENP 486
K IG+GS+ V LA + + + A K+ K+ + EK E +L K +++P
Sbjct: 197 KVIGKGSFGKVLLARH----KAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHP 252
Query: 487 HIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKN 666
++ +H Q +++ + Y + G+L ++R E +A+ + ++AS L YLHS N
Sbjct: 253 FLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLN 312
Query: 667 IAHRDLKCENILLSRRFNVKL 729
I +RDLK ENILL + ++ L
Sbjct: 313 IVYRDLKPENILLDSQGHIVL 333
>AL135839-3|CAI19720.1| 445|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 445
Score = 74.9 bits (176), Expect = 3e-13
Identities = 44/141 (31%), Positives = 76/141 (53%), Gaps = 1/141 (0%)
Frame = +1
Query: 310 KKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTK-IENP 486
K IG+GS+ V LA + + + A K+ K+ + EK E +L K +++P
Sbjct: 116 KVIGKGSFGKVLLARH----KAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHP 171
Query: 487 HIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKN 666
++ +H Q +++ + Y + G+L ++R E +A+ + ++AS L YLHS N
Sbjct: 172 FLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLN 231
Query: 667 IAHRDLKCENILLSRRFNVKL 729
I +RDLK ENILL + ++ L
Sbjct: 232 IVYRDLKPENILLDSQGHIVL 252
>AL135839-2|CAI19719.1| 431|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 431
Score = 74.9 bits (176), Expect = 3e-13
Identities = 44/141 (31%), Positives = 76/141 (53%), Gaps = 1/141 (0%)
Frame = +1
Query: 310 KKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTK-IENP 486
K IG+GS+ V LA + + + A K+ K+ + EK E +L K +++P
Sbjct: 102 KVIGKGSFGKVLLARH----KAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHP 157
Query: 487 HIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKN 666
++ +H Q +++ + Y + G+L ++R E +A+ + ++AS L YLHS N
Sbjct: 158 FLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLN 217
Query: 667 IAHRDLKCENILLSRRFNVKL 729
I +RDLK ENILL + ++ L
Sbjct: 218 IVYRDLKPENILLDSQGHIVL 238
>AL135839-1|CAI19718.1| 421|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 421
Score = 74.9 bits (176), Expect = 3e-13
Identities = 44/141 (31%), Positives = 76/141 (53%), Gaps = 1/141 (0%)
Frame = +1
Query: 310 KKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTK-IENP 486
K IG+GS+ V LA + + + A K+ K+ + EK E +L K +++P
Sbjct: 92 KVIGKGSFGKVLLARH----KAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHP 147
Query: 487 HIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKN 666
++ +H Q +++ + Y + G+L ++R E +A+ + ++AS L YLHS N
Sbjct: 148 FLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLN 207
Query: 667 IAHRDLKCENILLSRRFNVKL 729
I +RDLK ENILL + ++ L
Sbjct: 208 IVYRDLKPENILLDSQGHIVL 228
>AJ000512-1|CAA04146.1| 431|Homo sapiens serine/threonine protein
kinase protein.
Length = 431
Score = 74.9 bits (176), Expect = 3e-13
Identities = 44/141 (31%), Positives = 76/141 (53%), Gaps = 1/141 (0%)
Frame = +1
Query: 310 KKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTK-IENP 486
K IG+GS+ V LA + + + A K+ K+ + EK E +L K +++P
Sbjct: 102 KVIGKGSFGKVLLARH----KAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHP 157
Query: 487 HIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKN 666
++ +H Q +++ + Y + G+L ++R E +A+ + ++AS L YLHS N
Sbjct: 158 FLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLN 217
Query: 667 IAHRDLKCENILLSRRFNVKL 729
I +RDLK ENILL + ++ L
Sbjct: 218 IVYRDLKPENILLDSQGHIVL 238
>AF153609-1|AAD41091.1| 431|Homo sapiens serine/threonine protein
kinase sgk protein.
Length = 431
Score = 74.9 bits (176), Expect = 3e-13
Identities = 44/141 (31%), Positives = 76/141 (53%), Gaps = 1/141 (0%)
Frame = +1
Query: 310 KKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTK-IENP 486
K IG+GS+ V LA + + + A K+ K+ + EK E +L K +++P
Sbjct: 102 KVIGKGSFGKVLLARH----KAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHP 157
Query: 487 HIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKN 666
++ +H Q +++ + Y + G+L ++R E +A+ + ++AS L YLHS N
Sbjct: 158 FLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLN 217
Query: 667 IAHRDLKCENILLSRRFNVKL 729
I +RDLK ENILL + ++ L
Sbjct: 218 IVYRDLKPENILLDSQGHIVL 238
>AF045458-1|AAC32326.1| 1050|Homo sapiens serine/threonine kinase
ULK1 protein.
Length = 1050
Score = 74.9 bits (176), Expect = 3e-13
Identities = 38/131 (29%), Positives = 74/131 (56%)
Frame = +1
Query: 316 IGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKIENPHII 495
IG G++A V + + + +A K +K+ + + +E++IL ++++ +I+
Sbjct: 22 IGHGAFAVVFKGRHREKHD---LEVAVKCINKKNLAKS--QTLLGKEIKILKELKHENIV 76
Query: 496 QVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKNIAH 675
++ + V++ M Y + GDL D++ + E+ +L+ +Q+A ++ LHSK I H
Sbjct: 77 ALYDFQEMANSVYLVMEYCNGGDLADYLHAMRTLSEDTIRLFLQQIAGAMRLLHSKGIIH 136
Query: 676 RDLKCENILLS 708
RDLK +NILLS
Sbjct: 137 RDLKPQNILLS 147
>AB208871-1|BAD92108.1| 1433|Homo sapiens Hypothetical protein
DKFZp781I035 variant protein.
Length = 1433
Score = 74.9 bits (176), Expect = 3e-13
Identities = 44/142 (30%), Positives = 73/142 (51%), Gaps = 3/142 (2%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAP---RDFLEKFFPRELEIL 468
Y G+++G G +A V + C S + A K K + R + RE+ IL
Sbjct: 16 YDTGEELGSGQFAVV---KKCREKSTG-LQYAAKFIKKRRTKSSRRGVSREDIEREVSIL 71
Query: 469 TKIENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQ 648
+I++P++I +H + + V + + G+L DF+ + E +A + +Q+ +G+
Sbjct: 72 KEIQHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQILNGVY 131
Query: 649 YLHSKNIAHRDLKCENILLSRR 714
YLHS IAH DLK ENI+L R
Sbjct: 132 YLHSLQIAHFDLKPENIMLLDR 153
>AB072828-1|BAC15599.1| 489|Homo sapiens NIMA-related protein
kinase 3 protein.
Length = 489
Score = 74.9 bits (176), Expect = 3e-13
Identities = 44/147 (29%), Positives = 76/147 (51%), Gaps = 3/147 (2%)
Frame = +1
Query: 298 YLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPR-ELEILTK 474
Y++ + IG+G + L ++ S +M +I + P+ F R E +L K
Sbjct: 4 YMVLRMIGEGFFGRALLVQH---ESSNQMFAMKEI----RLPKSFSNTQNSRKEAVLLAK 56
Query: 475 IENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIK--RNGVVPENQAKLWFRQMASGLQ 648
+++P+I+ + ++I M Y D GDL+ IK + + PE+ WF QM G+
Sbjct: 57 MKHPNIVAFKESFEAEGHLYIVMEYCDGGDLMQKIKQQKGKLFPEDMILNWFTQMCLGVN 116
Query: 649 YLHSKNIAHRDLKCENILLSRRFNVKL 729
++H K + HRD+K +NI L++ VKL
Sbjct: 117 HIHKKRVLHRDIKSKNIFLTQNGKVKL 143
>AB018265-1|BAA34442.2| 1066|Homo sapiens KIAA0722 protein protein.
Length = 1066
Score = 74.9 bits (176), Expect = 3e-13
Identities = 38/131 (29%), Positives = 74/131 (56%)
Frame = +1
Query: 316 IGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKIENPHII 495
IG G++A V + + + +A K +K+ + + +E++IL ++++ +I+
Sbjct: 38 IGHGAFAVVFKGRHREKHD---LEVAVKCINKKNLAKS--QTLLGKEIKILKELKHENIV 92
Query: 496 QVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKNIAH 675
++ + V++ M Y + GDL D++ + E+ +L+ +Q+A ++ LHSK I H
Sbjct: 93 ALYDFQEMANSVYLVMEYCNGGDLADYLHAMRTLSEDTIRLFLQQIAGAMRLLHSKGIIH 152
Query: 676 RDLKCENILLS 708
RDLK +NILLS
Sbjct: 153 RDLKPQNILLS 163
>AY830839-1|AAW52510.1| 2434|Homo sapiens serine/threonine protein
kinase protein.
Length = 2434
Score = 74.5 bits (175), Expect = 4e-13
Identities = 41/141 (29%), Positives = 75/141 (53%), Gaps = 1/141 (0%)
Frame = +1
Query: 310 KKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAP-RDFLEKFFPRELEILTKIENP 486
K I G+Y V+ + + R A K +K+ R+ +++ F E +ILT ENP
Sbjct: 385 KLISNGAYGAVYFVRHKES----RQRFAMKKINKQNLILRNQIQQAFV-ERDILTFAENP 439
Query: 487 HIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKN 666
++ ++ + + + M Y + GD +K G +P + A+++F + L+YLH+
Sbjct: 440 FVVSMYCSFETRRHLCMVMEYVEGGDCATLMKNMGPLPVDMARMYFAETVLALEYLHNYG 499
Query: 667 IAHRDLKCENILLSRRFNVKL 729
I HRDLK +N+L++ ++KL
Sbjct: 500 IVHRDLKPDNLLVTSMGHIKL 520
>AB033104-1|BAA86592.1| 1311|Homo sapiens KIAA1278 protein protein.
Length = 1311
Score = 74.5 bits (175), Expect = 4e-13
Identities = 46/156 (29%), Positives = 81/156 (51%)
Frame = +1
Query: 262 RSSEVNALEQRGYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEK 441
R E + +E+ Y + + IG+GS+ V+ + + K+ EK R+
Sbjct: 11 RDPETSVMEK--YHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNL--- 65
Query: 442 FFPRELEILTKIENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLW 621
RE+EI+ + +P+I+ + + V + YA+ G+L ++ +G +PE+Q +
Sbjct: 66 --QREIEIMRGLRHPNIVHMLDSFETDKEVVVVTDYAE-GELFQILEDDGKLPEDQVQAI 122
Query: 622 FRQMASGLQYLHSKNIAHRDLKCENILLSRRFNVKL 729
Q+ S L YLHS I HRD+K +NILL++ +KL
Sbjct: 123 AAQLVSALYYLHSHRILHRDMKPQNILLAKGGGIKL 158
>AB002301-1|BAA20762.1| 2137|Homo sapiens KIAA0303 protein.
Length = 2137
Score = 74.5 bits (175), Expect = 4e-13
Identities = 41/141 (29%), Positives = 75/141 (53%), Gaps = 1/141 (0%)
Frame = +1
Query: 310 KKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAP-RDFLEKFFPRELEILTKIENP 486
K I G+Y V+ + + R A K +K+ R+ +++ F E +ILT ENP
Sbjct: 88 KLISNGAYGAVYFVRHKES----RQRFAMKKINKQNLILRNQIQQAFV-ERDILTFAENP 142
Query: 487 HIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKN 666
++ ++ + + + M Y + GD +K G +P + A+++F + L+YLH+
Sbjct: 143 FVVSMYCSFETRRHLCMVMEYVEGGDCATLMKNMGPLPVDMARMYFAETVLALEYLHNYG 202
Query: 667 IAHRDLKCENILLSRRFNVKL 729
I HRDLK +N+L++ ++KL
Sbjct: 203 IVHRDLKPDNLLVTSMGHIKL 223
>BC006106-1|AAH06106.3| 482|Homo sapiens ribosomal protein S6
kinase, 70kDa, polypeptide 2 protein.
Length = 482
Score = 74.1 bits (174), Expect = 5e-13
Identities = 40/139 (28%), Positives = 76/139 (54%), Gaps = 1/139 (0%)
Frame = +1
Query: 316 IGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPR-ELEILTKIENPHI 492
+G+G Y V G++ +++ A K+ K K R+ + R E IL +++P I
Sbjct: 73 LGKGGYGKVFQVRKVQGTNLGKIY-AMKVLRKAKIVRNAKDTAHTRAERNILESVKHPFI 131
Query: 493 IQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKNIA 672
+++ Q G ++++ + G+L ++R G+ E+ A + ++ L +LHS+ I
Sbjct: 132 VELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGHLHSQGII 191
Query: 673 HRDLKCENILLSRRFNVKL 729
+RDLK ENI+LS + ++KL
Sbjct: 192 YRDLKPENIMLSSQGHIKL 210
>BC000094-1|AAH00094.3| 482|Homo sapiens ribosomal protein S6
kinase, 70kDa, polypeptide 2 protein.
Length = 482
Score = 74.1 bits (174), Expect = 5e-13
Identities = 40/139 (28%), Positives = 76/139 (54%), Gaps = 1/139 (0%)
Frame = +1
Query: 316 IGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPR-ELEILTKIENPHI 492
+G+G Y V G++ +++ A K+ K K R+ + R E IL +++P I
Sbjct: 73 LGKGGYGKVFQVRKVQGTNLGKIY-AMKVLRKAKIVRNAKDTAHTRAERNILESVKHPFI 131
Query: 493 IQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKNIA 672
+++ Q G ++++ + G+L ++R G+ E+ A + ++ L +LHS+ I
Sbjct: 132 VELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGHLHSQGII 191
Query: 673 HRDLKCENILLSRRFNVKL 729
+RDLK ENI+LS + ++KL
Sbjct: 192 YRDLKPENIMLSSQGHIKL 210
>AF099739-1|AAD20990.1| 482|Homo sapiens S6 kinase-related kinase
protein.
Length = 482
Score = 74.1 bits (174), Expect = 5e-13
Identities = 40/139 (28%), Positives = 76/139 (54%), Gaps = 1/139 (0%)
Frame = +1
Query: 316 IGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPR-ELEILTKIENPHI 492
+G+G Y V G++ +++ A K+ K K R+ + R E IL +++P I
Sbjct: 73 LGKGGYGKVFQVRKVQGTNLGKIY-AMKVLRKAKIVRNAKDTAHTRAERNILESVKHPFI 131
Query: 493 IQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKNIA 672
+++ Q G ++++ + G+L ++R G+ E+ A + ++ L +LHS+ I
Sbjct: 132 VELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGHLHSQGII 191
Query: 673 HRDLKCENILLSRRFNVKL 729
+RDLK ENI+LS + ++KL
Sbjct: 192 YRDLKPENIMLSSQGHIKL 210
>AF076931-1|AAD46063.1| 482|Homo sapiens serine/threonine kinase 14
beta protein.
Length = 482
Score = 74.1 bits (174), Expect = 5e-13
Identities = 40/139 (28%), Positives = 76/139 (54%), Gaps = 1/139 (0%)
Frame = +1
Query: 316 IGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPR-ELEILTKIENPHI 492
+G+G Y V G++ +++ A K+ K K R+ + R E IL +++P I
Sbjct: 73 LGKGGYGKVFQVRKVQGTNLGKIY-AMKVLRKAKIVRNAKDTAHTRAERNILESVKHPFI 131
Query: 493 IQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKNIA 672
+++ Q G ++++ + G+L ++R G+ E+ A + ++ L +LHS+ I
Sbjct: 132 VELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGHLHSQGII 191
Query: 673 HRDLKCENILLSRRFNVKL 729
+RDLK ENI+LS + ++KL
Sbjct: 192 YRDLKPENIMLSSQGHIKL 210
>AB016869-1|BAA34402.1| 495|Homo sapiens p70 ribosomal S6 kinase
beta protein.
Length = 495
Score = 74.1 bits (174), Expect = 5e-13
Identities = 40/139 (28%), Positives = 76/139 (54%), Gaps = 1/139 (0%)
Frame = +1
Query: 316 IGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPR-ELEILTKIENPHI 492
+G+G Y V G++ +++ A K+ K K R+ + R E IL +++P I
Sbjct: 86 LGKGGYGKVFQVRKVQGTNLGKIY-AMKVLRKAKIVRNAKDTAHTRAERNILESVKHPFI 144
Query: 493 IQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKNIA 672
+++ Q G ++++ + G+L ++R G+ E+ A + ++ L +LHS+ I
Sbjct: 145 VELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGHLHSQGII 204
Query: 673 HRDLKCENILLSRRFNVKL 729
+RDLK ENI+LS + ++KL
Sbjct: 205 YRDLKPENIMLSSQGHIKL 223
>AL390029-2|CAI15721.1| 740|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 740
Score = 73.7 bits (173), Expect = 6e-13
Identities = 46/153 (30%), Positives = 74/153 (48%)
Frame = +1
Query: 247 DRLSPRSSEVNALEQRGYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPR 426
+ +S ++ A Y +G+ IG G++A V + C S R + A KI K K
Sbjct: 373 EEVSEEGFQIPATITERYKVGRTIGDGNFAVV---KECVERSTAREY-ALKIIKKSKCRG 428
Query: 427 DFLEKFFPRELEILTKIENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPEN 606
E E+ IL ++++P+I+ + + +++ M GDL D I E
Sbjct: 429 K--EHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTER 486
Query: 607 QAKLWFRQMASGLQYLHSKNIAHRDLKCENILL 705
A +AS ++YLHS NI HRD+K EN+L+
Sbjct: 487 DASGMLYNLASAIKYLHSLNIVHRDIKPENLLV 519
>AL390029-1|CAI15720.1| 729|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 729
Score = 73.7 bits (173), Expect = 6e-13
Identities = 46/153 (30%), Positives = 74/153 (48%)
Frame = +1
Query: 247 DRLSPRSSEVNALEQRGYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPR 426
+ +S ++ A Y +G+ IG G++A V + C S R + A KI K K
Sbjct: 373 EEVSEEGFQIPATITERYKVGRTIGDGNFAVV---KECVERSTAREY-ALKIIKKSKCRG 428
Query: 427 DFLEKFFPRELEILTKIENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPEN 606
E E+ IL ++++P+I+ + + +++ M GDL D I E
Sbjct: 429 K--EHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTER 486
Query: 607 QAKLWFRQMASGLQYLHSKNIAHRDLKCENILL 705
A +AS ++YLHS NI HRD+K EN+L+
Sbjct: 487 DASGMLYNLASAIKYLHSLNIVHRDIKPENLLV 519
>AL160392-2|CAH70261.1| 740|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 740
Score = 73.7 bits (173), Expect = 6e-13
Identities = 46/153 (30%), Positives = 74/153 (48%)
Frame = +1
Query: 247 DRLSPRSSEVNALEQRGYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPR 426
+ +S ++ A Y +G+ IG G++A V + C S R + A KI K K
Sbjct: 373 EEVSEEGFQIPATITERYKVGRTIGDGNFAVV---KECVERSTAREY-ALKIIKKSKCRG 428
Query: 427 DFLEKFFPRELEILTKIENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPEN 606
E E+ IL ++++P+I+ + + +++ M GDL D I E
Sbjct: 429 K--EHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTER 486
Query: 607 QAKLWFRQMASGLQYLHSKNIAHRDLKCENILL 705
A +AS ++YLHS NI HRD+K EN+L+
Sbjct: 487 DASGMLYNLASAIKYLHSLNIVHRDIKPENLLV 519
>AL160392-1|CAH70262.1| 729|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 729
Score = 73.7 bits (173), Expect = 6e-13
Identities = 46/153 (30%), Positives = 74/153 (48%)
Frame = +1
Query: 247 DRLSPRSSEVNALEQRGYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPR 426
+ +S ++ A Y +G+ IG G++A V + C S R + A KI K K
Sbjct: 373 EEVSEEGFQIPATITERYKVGRTIGDGNFAVV---KECVERSTAREY-ALKIIKKSKCRG 428
Query: 427 DFLEKFFPRELEILTKIENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPEN 606
E E+ IL ++++P+I+ + + +++ M GDL D I E
Sbjct: 429 K--EHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTER 486
Query: 607 QAKLWFRQMASGLQYLHSKNIAHRDLKCENILL 705
A +AS ++YLHS NI HRD+K EN+L+
Sbjct: 487 DASGMLYNLASAIKYLHSLNIVHRDIKPENLLV 519
>AL157760-4|CAH70170.1| 433|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 433
Score = 73.7 bits (173), Expect = 6e-13
Identities = 46/153 (30%), Positives = 74/153 (48%)
Frame = +1
Query: 247 DRLSPRSSEVNALEQRGYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPR 426
+ +S ++ A Y +G+ IG G++A V + C S R + A KI K K
Sbjct: 66 EEVSEEGFQIPATITERYKVGRTIGDGNFAVV---KECVERSTAREY-ALKIIKKSKCRG 121
Query: 427 DFLEKFFPRELEILTKIENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPEN 606
E E+ IL ++++P+I+ + + +++ M GDL D I E
Sbjct: 122 K--EHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTER 179
Query: 607 QAKLWFRQMASGLQYLHSKNIAHRDLKCENILL 705
A +AS ++YLHS NI HRD+K EN+L+
Sbjct: 180 DASGMLYNLASAIKYLHSLNIVHRDIKPENLLV 212
>AL157760-2|CAH70167.1| 740|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 740
Score = 73.7 bits (173), Expect = 6e-13
Identities = 46/153 (30%), Positives = 74/153 (48%)
Frame = +1
Query: 247 DRLSPRSSEVNALEQRGYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPR 426
+ +S ++ A Y +G+ IG G++A V + C S R + A KI K K
Sbjct: 373 EEVSEEGFQIPATITERYKVGRTIGDGNFAVV---KECVERSTAREY-ALKIIKKSKCRG 428
Query: 427 DFLEKFFPRELEILTKIENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPEN 606
E E+ IL ++++P+I+ + + +++ M GDL D I E
Sbjct: 429 K--EHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTER 486
Query: 607 QAKLWFRQMASGLQYLHSKNIAHRDLKCENILL 705
A +AS ++YLHS NI HRD+K EN+L+
Sbjct: 487 DASGMLYNLASAIKYLHSLNIVHRDIKPENLLV 519
>AL157760-1|CAH70168.1| 729|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 729
Score = 73.7 bits (173), Expect = 6e-13
Identities = 46/153 (30%), Positives = 74/153 (48%)
Frame = +1
Query: 247 DRLSPRSSEVNALEQRGYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPR 426
+ +S ++ A Y +G+ IG G++A V + C S R + A KI K K
Sbjct: 373 EEVSEEGFQIPATITERYKVGRTIGDGNFAVV---KECVERSTAREY-ALKIIKKSKCRG 428
Query: 427 DFLEKFFPRELEILTKIENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPEN 606
E E+ IL ++++P+I+ + + +++ M GDL D I E
Sbjct: 429 K--EHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTER 486
Query: 607 QAKLWFRQMASGLQYLHSKNIAHRDLKCENILL 705
A +AS ++YLHS NI HRD+K EN+L+
Sbjct: 487 DASGMLYNLASAIKYLHSLNIVHRDIKPENLLV 519
>AL157694-2|CAH70656.1| 740|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 740
Score = 73.7 bits (173), Expect = 6e-13
Identities = 46/153 (30%), Positives = 74/153 (48%)
Frame = +1
Query: 247 DRLSPRSSEVNALEQRGYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPR 426
+ +S ++ A Y +G+ IG G++A V + C S R + A KI K K
Sbjct: 373 EEVSEEGFQIPATITERYKVGRTIGDGNFAVV---KECVERSTAREY-ALKIIKKSKCRG 428
Query: 427 DFLEKFFPRELEILTKIENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPEN 606
E E+ IL ++++P+I+ + + +++ M GDL D I E
Sbjct: 429 K--EHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTER 486
Query: 607 QAKLWFRQMASGLQYLHSKNIAHRDLKCENILL 705
A +AS ++YLHS NI HRD+K EN+L+
Sbjct: 487 DASGMLYNLASAIKYLHSLNIVHRDIKPENLLV 519
>AL157694-1|CAH70657.1| 729|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 729
Score = 73.7 bits (173), Expect = 6e-13
Identities = 46/153 (30%), Positives = 74/153 (48%)
Frame = +1
Query: 247 DRLSPRSSEVNALEQRGYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPR 426
+ +S ++ A Y +G+ IG G++A V + C S R + A KI K K
Sbjct: 373 EEVSEEGFQIPATITERYKVGRTIGDGNFAVV---KECVERSTAREY-ALKIIKKSKCRG 428
Query: 427 DFLEKFFPRELEILTKIENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPEN 606
E E+ IL ++++P+I+ + + +++ M GDL D I E
Sbjct: 429 K--EHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTER 486
Query: 607 QAKLWFRQMASGLQYLHSKNIAHRDLKCENILL 705
A +AS ++YLHS NI HRD+K EN+L+
Sbjct: 487 DASGMLYNLASAIKYLHSLNIVHRDIKPENLLV 519
>AK075004-1|BAC11348.1| 423|Homo sapiens protein ( Homo sapiens
cDNA FLJ90523 fis, clone NT2RP4000634, highly similar to
Homo sapiens mitogen-activated protein kinase kinase
kinase ).
Length = 423
Score = 73.7 bits (173), Expect = 6e-13
Identities = 50/162 (30%), Positives = 79/162 (48%), Gaps = 3/162 (1%)
Frame = +1
Query: 253 LSPRSSEVNALEQRGYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDF 432
+SP S A + +GK +GQG++ V+L D + + + + FD +
Sbjct: 147 ISPPSRSPRA--PTNWRLGKLLGQGAFGRVYLCY--DVDTGRELAVKQVQFDPDSPETSK 202
Query: 433 LEKFFPRELEILTKIENPHIIQVHSILQRGPR---VFIFMRYADNGDLLDFIKRNGVVPE 603
E+++L + + I+Q + L R P+ + IFM Y G + D +K G + E
Sbjct: 203 EVNALECEIQLLKNLLHERIVQYYGCL-RDPQEKTLSIFMEYMPGGSIKDQLKAYGALTE 261
Query: 604 NQAKLWFRQMASGLQYLHSKNIAHRDLKCENILLSRRFNVKL 729
N + + RQ+ G+ YLHS I HRD+K NIL NVKL
Sbjct: 262 NVTRKYTRQILEGVHYLHSNMIVHRDIKGANILRDSTGNVKL 303
>AF239798-1|AAF63496.1| 619|Homo sapiens protein kinase MEKK2b
protein.
Length = 619
Score = 73.7 bits (173), Expect = 6e-13
Identities = 50/162 (30%), Positives = 79/162 (48%), Gaps = 3/162 (1%)
Frame = +1
Query: 253 LSPRSSEVNALEQRGYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDF 432
+SP S A + +GK +GQG++ V+L D + + + + FD +
Sbjct: 343 ISPPSRSPRA--PTNWRLGKLLGQGAFGRVYLCY--DVDTGRELAVKQVQFDPDSPETSK 398
Query: 433 LEKFFPRELEILTKIENPHIIQVHSILQRGPR---VFIFMRYADNGDLLDFIKRNGVVPE 603
E+++L + + I+Q + L R P+ + IFM Y G + D +K G + E
Sbjct: 399 EVNALECEIQLLKNLLHERIVQYYGCL-RDPQEKTLSIFMEYMPGGSIKDQLKAYGALTE 457
Query: 604 NQAKLWFRQMASGLQYLHSKNIAHRDLKCENILLSRRFNVKL 729
N + + RQ+ G+ YLHS I HRD+K NIL NVKL
Sbjct: 458 NVTRKYTRQILEGVHYLHSNMIVHRDIKGANILRDSTGNVKL 499
>AB208963-1|BAD92200.1| 621|Homo sapiens Protein kinase MEKK2b
variant protein.
Length = 621
Score = 73.7 bits (173), Expect = 6e-13
Identities = 50/162 (30%), Positives = 79/162 (48%), Gaps = 3/162 (1%)
Frame = +1
Query: 253 LSPRSSEVNALEQRGYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDF 432
+SP S A + +GK +GQG++ V+L D + + + + FD +
Sbjct: 345 ISPPSRSPRA--PTNWRLGKLLGQGAFGRVYLCY--DVDTGRELAVKQVQFDPDSPETSK 400
Query: 433 LEKFFPRELEILTKIENPHIIQVHSILQRGPR---VFIFMRYADNGDLLDFIKRNGVVPE 603
E+++L + + I+Q + L R P+ + IFM Y G + D +K G + E
Sbjct: 401 EVNALECEIQLLKNLLHERIVQYYGCL-RDPQEKTLSIFMEYMPGGSIKDQLKAYGALTE 459
Query: 604 NQAKLWFRQMASGLQYLHSKNIAHRDLKCENILLSRRFNVKL 729
N + + RQ+ G+ YLHS I HRD+K NIL NVKL
Sbjct: 460 NVTRKYTRQILEGVHYLHSNMIVHRDIKGANILRDSTGNVKL 501
>AB002367-1|BAA20824.2| 794|Homo sapiens KIAA0369 protein.
Length = 794
Score = 73.7 bits (173), Expect = 6e-13
Identities = 46/153 (30%), Positives = 74/153 (48%)
Frame = +1
Query: 247 DRLSPRSSEVNALEQRGYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPR 426
+ +S ++ A Y +G+ IG G++A V + C S R + A KI K K
Sbjct: 438 EEVSEEGFQIPATITERYKVGRTIGDGNFAVV---KECVERSTAREY-ALKIIKKSKCRG 493
Query: 427 DFLEKFFPRELEILTKIENPHIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPEN 606
E E+ IL ++++P+I+ + + +++ M GDL D I E
Sbjct: 494 K--EHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTER 551
Query: 607 QAKLWFRQMASGLQYLHSKNIAHRDLKCENILL 705
A +AS ++YLHS NI HRD+K EN+L+
Sbjct: 552 DASGMLYNLASAIKYLHSLNIVHRDIKPENLLV 584
>X99325-1|CAA67700.1| 426|Homo sapiens Ste20-like kinase protein.
Length = 426
Score = 73.3 bits (172), Expect = 8e-13
Identities = 46/140 (32%), Positives = 76/140 (54%)
Frame = +1
Query: 313 KIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKIENPHI 492
+IG+GS+ V Y + + +A KI D E+A D +E +E+ +L++ ++P+I
Sbjct: 25 RIGKGSFGEV----YKGIDNHTKEVVAIKIIDLEEA-EDEIEDI-QQEITVLSQCDSPYI 78
Query: 493 IQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKNIA 672
+ + +++I M Y G LD +K G + E R++ GL YLHS+
Sbjct: 79 TRYFGSYLKSTKLWIIMEYLGGGSALDLLKP-GPLEETYIATILREILKGLDYLHSERKI 137
Query: 673 HRDLKCENILLSRRFNVKLA 732
HRD+K N+LLS + +VKLA
Sbjct: 138 HRDIKAANVLLSEQGDVKLA 157
>D63780-1|BAA20420.1| 426|Homo sapiens YSK1 protein.
Length = 426
Score = 73.3 bits (172), Expect = 8e-13
Identities = 46/140 (32%), Positives = 76/140 (54%)
Frame = +1
Query: 313 KIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKIENPHI 492
+IG+GS+ V Y + + +A KI D E+A D +E +E+ +L++ ++P+I
Sbjct: 25 RIGKGSFGEV----YKGIDNHTKEVVAIKIIDLEEA-EDEIEDI-QQEITVLSQCDSPYI 78
Query: 493 IQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKNIA 672
+ + +++I M Y G LD +K G + E R++ GL YLHS+
Sbjct: 79 TRYFGSYLKSTKLWIIMEYLGGGSALDLLKP-GPLEETYIATILREILKGLDYLHSERKI 137
Query: 673 HRDLKCENILLSRRFNVKLA 732
HRD+K N+LLS + +VKLA
Sbjct: 138 HRDIKAANVLLSEQGDVKLA 157
>DQ093965-1|AAY88740.1| 426|Homo sapiens serine/threonine kinase 25
(STE20 homolog, yeast) protein.
Length = 426
Score = 73.3 bits (172), Expect = 8e-13
Identities = 46/140 (32%), Positives = 76/140 (54%)
Frame = +1
Query: 313 KIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKIENPHI 492
+IG+GS+ V Y + + +A KI D E+A D +E +E+ +L++ ++P+I
Sbjct: 25 RIGKGSFGEV----YKGIDNHTKEVVAIKIIDLEEA-EDEIEDI-QQEITVLSQCDSPYI 78
Query: 493 IQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKNIA 672
+ + +++I M Y G LD +K G + E R++ GL YLHS+
Sbjct: 79 TRYFGSYLKSTKLWIIMEYLGGGSALDLLKP-GPLEETYIATILREILKGLDYLHSERKI 137
Query: 673 HRDLKCENILLSRRFNVKLA 732
HRD+K N+LLS + +VKLA
Sbjct: 138 HRDIKAANVLLSEQGDVKLA 157
>BT019961-1|AAV38764.1| 426|Homo sapiens serine/threonine kinase 25
(STE20 homolog, yeast) protein.
Length = 426
Score = 73.3 bits (172), Expect = 8e-13
Identities = 46/140 (32%), Positives = 76/140 (54%)
Frame = +1
Query: 313 KIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKIENPHI 492
+IG+GS+ V Y + + +A KI D E+A D +E +E+ +L++ ++P+I
Sbjct: 25 RIGKGSFGEV----YKGIDNHTKEVVAIKIIDLEEA-EDEIEDI-QQEITVLSQCDSPYI 78
Query: 493 IQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKNIA 672
+ + +++I M Y G LD +K G + E R++ GL YLHS+
Sbjct: 79 TRYFGSYLKSTKLWIIMEYLGGGSALDLLKP-GPLEETYIATILREILKGLDYLHSERKI 137
Query: 673 HRDLKCENILLSRRFNVKLA 732
HRD+K N+LLS + +VKLA
Sbjct: 138 HRDIKAANVLLSEQGDVKLA 157
>BC091505-1|AAH91505.1| 426|Homo sapiens STK25 protein protein.
Length = 426
Score = 73.3 bits (172), Expect = 8e-13
Identities = 46/140 (32%), Positives = 76/140 (54%)
Frame = +1
Query: 313 KIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKIENPHI 492
+IG+GS+ V Y + + +A KI D E+A D +E +E+ +L++ ++P+I
Sbjct: 25 RIGKGSFGEV----YKGIDNHTKEVVAIKIIDLEEA-EDEIEDI-QQEITVLSQCDSPYI 78
Query: 493 IQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKNIA 672
+ + +++I M Y G LD +K G + E R++ GL YLHS+
Sbjct: 79 TRYFGSYLKSTKLWIIMEYLGGGSALDLLKP-GPLEETYIATILREILKGLDYLHSERKI 137
Query: 673 HRDLKCENILLSRRFNVKLA 732
HRD+K N+LLS + +VKLA
Sbjct: 138 HRDIKAANVLLSEQGDVKLA 157
>BC015793-1|AAH15793.1| 426|Homo sapiens STK25 protein protein.
Length = 426
Score = 73.3 bits (172), Expect = 8e-13
Identities = 46/140 (32%), Positives = 76/140 (54%)
Frame = +1
Query: 313 KIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKIENPHI 492
+IG+GS+ V Y + + +A KI D E+A D +E +E+ +L++ ++P+I
Sbjct: 25 RIGKGSFGEV----YKGIDNHTKEVVAIKIIDLEEA-EDEIEDI-QQEITVLSQCDSPYI 78
Query: 493 IQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKNIA 672
+ + +++I M Y G LD +K G + E R++ GL YLHS+
Sbjct: 79 TRYFGSYLKSTKLWIIMEYLGGGSALDLLKP-GPLEETYIATILREILKGLDYLHSERKI 137
Query: 673 HRDLKCENILLSRRFNVKLA 732
HRD+K N+LLS + +VKLA
Sbjct: 138 HRDIKAANVLLSEQGDVKLA 157
>BC007852-1|AAH07852.1| 426|Homo sapiens serine/threonine kinase 25
(STE20 homolog, yeast) protein.
Length = 426
Score = 73.3 bits (172), Expect = 8e-13
Identities = 46/140 (32%), Positives = 76/140 (54%)
Frame = +1
Query: 313 KIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKIENPHI 492
+IG+GS+ V Y + + +A KI D E+A D +E +E+ +L++ ++P+I
Sbjct: 25 RIGKGSFGEV----YKGIDNHTKEVVAIKIIDLEEA-EDEIEDI-QQEITVLSQCDSPYI 78
Query: 493 IQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKNIA 672
+ + +++I M Y G LD +K G + E R++ GL YLHS+
Sbjct: 79 TRYFGSYLKSTKLWIIMEYLGGGSALDLLKP-GPLEETYIATILREILKGLDYLHSERKI 137
Query: 673 HRDLKCENILLSRRFNVKLA 732
HRD+K N+LLS + +VKLA
Sbjct: 138 HRDIKAANVLLSEQGDVKLA 157
>AC110926-2|AAY15070.1| 270|Homo sapiens unknown protein.
Length = 270
Score = 73.3 bits (172), Expect = 8e-13
Identities = 46/145 (31%), Positives = 73/145 (50%), Gaps = 3/145 (2%)
Frame = +1
Query: 304 IGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKIEN 483
+GK +GQG++ V+L D + + + + FD + E+++L + +
Sbjct: 9 LGKLLGQGAFGRVYLCY--DVDTGRELAVKQVQFDPDSPETSKEVNALECEIQLLKNLLH 66
Query: 484 PHIIQVHSILQRGPR---VFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYL 654
I+Q + L R P+ + IFM Y G + D +K G + EN + + RQ+ G+ YL
Sbjct: 67 ERIVQYYGCL-RDPQEKTLSIFMEYMPGGSIKDQLKAYGALTENVTRKYTRQILEGVHYL 125
Query: 655 HSKNIAHRDLKCENILLSRRFNVKL 729
HS I HRD+K NIL NVKL
Sbjct: 126 HSNMIVHRDIKGANILRDSTGNVKL 150
>AC110299-2|AAY14683.1| 426|Homo sapiens unknown protein.
Length = 426
Score = 73.3 bits (172), Expect = 8e-13
Identities = 46/140 (32%), Positives = 76/140 (54%)
Frame = +1
Query: 313 KIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAPRDFLEKFFPRELEILTKIENPHI 492
+IG+GS+ V Y + + +A KI D E+A D +E +E+ +L++ ++P+I
Sbjct: 25 RIGKGSFGEV----YKGIDNHTKEVVAIKIIDLEEA-EDEIEDI-QQEITVLSQCDSPYI 78
Query: 493 IQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKNIA 672
+ + +++I M Y G LD +K G + E R++ GL YLHS+
Sbjct: 79 TRYFGSYLKSTKLWIIMEYLGGGSALDLLKP-GPLEETYIATILREILKGLDYLHSERKI 137
Query: 673 HRDLKCENILLSRRFNVKLA 732
HRD+K N+LLS + +VKLA
Sbjct: 138 HRDIKAANVLLSEQGDVKLA 157
>AB209475-1|BAD92712.1| 461|Homo sapiens protein kinase C, alpha
variant protein.
Length = 461
Score = 73.3 bits (172), Expect = 8e-13
Identities = 48/167 (28%), Positives = 87/167 (52%), Gaps = 1/167 (0%)
Frame = +1
Query: 235 SSMADRLSPRSSEVNALEQRGYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKE 414
S DR P S+ ++ ++ + +G+GS+ V LA D + ++ A KI K+
Sbjct: 230 SPSEDRKQP-SNNLDRVKLTDFNFLMVLGKGSFGKVMLA---DRKGTEELY-AIKILKKD 284
Query: 415 KAPRDFLEKFFPRELEILTKIENPHII-QVHSILQRGPRVFIFMRYADNGDLLDFIKRNG 591
+D + E +L ++ P + Q+HS Q R++ M Y + GDL+ I++ G
Sbjct: 285 VVIQDDDVECTMVEKRVLALLDKPPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVG 344
Query: 592 VVPENQAKLWFRQMASGLQYLHSKNIAHRDLKCENILLSRRFNVKLA 732
E QA + +++ GL +LH + I +RDLK +N++L ++K+A
Sbjct: 345 KFKEPQAVFYVAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIA 391
>X52479-1|CAA36718.1| 672|Homo sapiens protein ( Human PKC alpha
mRNA for protein kinase C alpha. ).
Length = 672
Score = 72.9 bits (171), Expect = 1e-12
Identities = 48/167 (28%), Positives = 87/167 (52%), Gaps = 1/167 (0%)
Frame = +1
Query: 235 SSMADRLSPRSSEVNALEQRGYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKE 414
S DR P S+ ++ ++ + +G+GS+ V LA D + ++ A KI K+
Sbjct: 319 SPSEDRKQP-SNNLDRVKLTDFNFLMVLGKGSFGKVMLA---DRKGTEELY-AIKILKKD 373
Query: 415 KAPRDFLEKFFPRELEILTKIENPHII-QVHSILQRGPRVFIFMRYADNGDLLDFIKRNG 591
+D + E +L ++ P + Q+HS Q R++ M Y + GDL+ I++ G
Sbjct: 374 VVIQDDDVECTMVEKRVLALLDKPPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVG 433
Query: 592 VVPENQAKLWFRQMASGLQYLHSKNIAHRDLKCENILLSRRFNVKLA 732
E QA + +++ GL +LH + I +RDLK +N++L ++K+A
Sbjct: 434 KFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIA 480
>BC109274-1|AAI09275.1| 672|Homo sapiens protein kinase C, alpha
protein.
Length = 672
Score = 72.9 bits (171), Expect = 1e-12
Identities = 48/167 (28%), Positives = 87/167 (52%), Gaps = 1/167 (0%)
Frame = +1
Query: 235 SSMADRLSPRSSEVNALEQRGYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKE 414
S DR P S+ ++ ++ + +G+GS+ V LA D + ++ A KI K+
Sbjct: 319 SPSEDRKQP-SNNLDRVKLTDFNFLMVLGKGSFGKVMLA---DRKGTEELY-AIKILKKD 373
Query: 415 KAPRDFLEKFFPRELEILTKIENPHII-QVHSILQRGPRVFIFMRYADNGDLLDFIKRNG 591
+D + E +L ++ P + Q+HS Q R++ M Y + GDL+ I++ G
Sbjct: 374 VVIQDDDVECTMVEKRVLALLDKPPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVG 433
Query: 592 VVPENQAKLWFRQMASGLQYLHSKNIAHRDLKCENILLSRRFNVKLA 732
E QA + +++ GL +LH + I +RDLK +N++L ++K+A
Sbjct: 434 KFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIA 480
>BC109273-1|AAI09274.1| 672|Homo sapiens protein kinase C, alpha
protein.
Length = 672
Score = 72.9 bits (171), Expect = 1e-12
Identities = 48/167 (28%), Positives = 87/167 (52%), Gaps = 1/167 (0%)
Frame = +1
Query: 235 SSMADRLSPRSSEVNALEQRGYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKE 414
S DR P S+ ++ ++ + +G+GS+ V LA D + ++ A KI K+
Sbjct: 319 SPSEDRKQP-SNNLDRVKLTDFNFLMVLGKGSFGKVMLA---DRKGTEELY-AIKILKKD 373
Query: 415 KAPRDFLEKFFPRELEILTKIENPHII-QVHSILQRGPRVFIFMRYADNGDLLDFIKRNG 591
+D + E +L ++ P + Q+HS Q R++ M Y + GDL+ I++ G
Sbjct: 374 VVIQDDDVECTMVEKRVLALLDKPPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVG 433
Query: 592 VVPENQAKLWFRQMASGLQYLHSKNIAHRDLKCENILLSRRFNVKLA 732
E QA + +++ GL +LH + I +RDLK +N++L ++K+A
Sbjct: 434 KFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIA 480
>BC065499-1|AAH65499.1| 1797|Homo sapiens microtubule associated
serine/threonine kinase 2 protein.
Length = 1797
Score = 72.9 bits (171), Expect = 1e-12
Identities = 42/141 (29%), Positives = 71/141 (50%), Gaps = 1/141 (0%)
Frame = +1
Query: 310 KKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAP-RDFLEKFFPRELEILTKIENP 486
K I G+Y V L + R A K +K+ R+ +++ F E +ILT ENP
Sbjct: 516 KLISNGAYGAVFLVRH----KSTRQRFAMKKINKQNLILRNQIQQAFV-ERDILTFAENP 570
Query: 487 HIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKN 666
++ + + + M Y + GD +K G +P + +L+F + L+YLH+
Sbjct: 571 FVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETVLALEYLHNYG 630
Query: 667 IAHRDLKCENILLSRRFNVKL 729
I HRDLK +N+L++ ++KL
Sbjct: 631 IVHRDLKPDNLLITSMGHIKL 651
>BC015816-1|AAH15816.2| 792|Homo sapiens MAST2 protein protein.
Length = 792
Score = 72.9 bits (171), Expect = 1e-12
Identities = 42/141 (29%), Positives = 71/141 (50%), Gaps = 1/141 (0%)
Frame = +1
Query: 310 KKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAP-RDFLEKFFPRELEILTKIENP 486
K I G+Y V L + R A K +K+ R+ +++ F E +ILT ENP
Sbjct: 154 KLISNGAYGAVFLVRH----KSTRQRFAMKKINKQNLILRNQIQQAFV-ERDILTFAENP 208
Query: 487 HIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKN 666
++ + + + M Y + GD +K G +P + +L+F + L+YLH+
Sbjct: 209 FVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETVLALEYLHNYG 268
Query: 667 IAHRDLKCENILLSRRFNVKL 729
I HRDLK +N+L++ ++KL
Sbjct: 269 IVHRDLKPDNLLITSMGHIKL 289
>BC006166-1|AAH06166.1| 792|Homo sapiens MAST2 protein protein.
Length = 792
Score = 72.9 bits (171), Expect = 1e-12
Identities = 42/141 (29%), Positives = 71/141 (50%), Gaps = 1/141 (0%)
Frame = +1
Query: 310 KKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAP-RDFLEKFFPRELEILTKIENP 486
K I G+Y V L + R A K +K+ R+ +++ F E +ILT ENP
Sbjct: 154 KLISNGAYGAVFLVRH----KSTRQRFAMKKINKQNLILRNQIQQAFV-ERDILTFAENP 208
Query: 487 HIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKN 666
++ + + + M Y + GD +K G +P + +L+F + L+YLH+
Sbjct: 209 FVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETVLALEYLHNYG 268
Query: 667 IAHRDLKCENILLSRRFNVKL 729
I HRDLK +N+L++ ++KL
Sbjct: 269 IVHRDLKPDNLLITSMGHIKL 289
>AY633609-1|AAV33302.1| 672|Homo sapiens aging-associated gene 6
protein protein.
Length = 672
Score = 72.9 bits (171), Expect = 1e-12
Identities = 48/167 (28%), Positives = 87/167 (52%), Gaps = 1/167 (0%)
Frame = +1
Query: 235 SSMADRLSPRSSEVNALEQRGYLIGKKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKE 414
S DR P S+ ++ ++ + +G+GS+ V LA D + ++ A KI K+
Sbjct: 319 SPSEDRKQP-SNNLDRVKLTDFNFLMVLGKGSFGKVMLA---DRKGTEELY-AIKILKKD 373
Query: 415 KAPRDFLEKFFPRELEILTKIENPHII-QVHSILQRGPRVFIFMRYADNGDLLDFIKRNG 591
+D + E +L ++ P + Q+HS Q R++ M Y + GDL+ I++ G
Sbjct: 374 VVIQDDDVECTMVEKRVLALLDKPPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVG 433
Query: 592 VVPENQAKLWFRQMASGLQYLHSKNIAHRDLKCENILLSRRFNVKLA 732
E QA + +++ GL +LH + I +RDLK +N++L ++K+A
Sbjct: 434 KFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIA 480
>AL645480-2|CAH73245.1| 792|Homo sapiens microtubule associated
serine/threonine kinase 2 protein.
Length = 792
Score = 72.9 bits (171), Expect = 1e-12
Identities = 42/141 (29%), Positives = 71/141 (50%), Gaps = 1/141 (0%)
Frame = +1
Query: 310 KKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAP-RDFLEKFFPRELEILTKIENP 486
K I G+Y V L + R A K +K+ R+ +++ F E +ILT ENP
Sbjct: 401 KLISNGAYGAVFLVRH----KSTRQRFAMKKINKQNLILRNQIQQAFV-ERDILTFAENP 455
Query: 487 HIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKN 666
++ + + + M Y + GD +K G +P + +L+F + L+YLH+
Sbjct: 456 FVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETVLALEYLHNYG 515
Query: 667 IAHRDLKCENILLSRRFNVKL 729
I HRDLK +N+L++ ++KL
Sbjct: 516 IVHRDLKPDNLLITSMGHIKL 536
>AL645480-1|CAH73244.1| 1798|Homo sapiens microtubule associated
serine/threonine kinase 2 protein.
Length = 1798
Score = 72.9 bits (171), Expect = 1e-12
Identities = 42/141 (29%), Positives = 71/141 (50%), Gaps = 1/141 (0%)
Frame = +1
Query: 310 KKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAP-RDFLEKFFPRELEILTKIENP 486
K I G+Y V L + R A K +K+ R+ +++ F E +ILT ENP
Sbjct: 516 KLISNGAYGAVFLVRH----KSTRQRFAMKKINKQNLILRNQIQQAFV-ERDILTFAENP 570
Query: 487 HIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKN 666
++ + + + M Y + GD +K G +P + +L+F + L+YLH+
Sbjct: 571 FVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETVLALEYLHNYG 630
Query: 667 IAHRDLKCENILLSRRFNVKL 729
I HRDLK +N+L++ ++KL
Sbjct: 631 IVHRDLKPDNLLITSMGHIKL 651
>AL603888-3|CAI16563.1| 792|Homo sapiens microtubule associated
serine/threonine kinase 2 protein.
Length = 792
Score = 72.9 bits (171), Expect = 1e-12
Identities = 42/141 (29%), Positives = 71/141 (50%), Gaps = 1/141 (0%)
Frame = +1
Query: 310 KKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAP-RDFLEKFFPRELEILTKIENP 486
K I G+Y V L + R A K +K+ R+ +++ F E +ILT ENP
Sbjct: 401 KLISNGAYGAVFLVRH----KSTRQRFAMKKINKQNLILRNQIQQAFV-ERDILTFAENP 455
Query: 487 HIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKN 666
++ + + + M Y + GD +K G +P + +L+F + L+YLH+
Sbjct: 456 FVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETVLALEYLHNYG 515
Query: 667 IAHRDLKCENILLSRRFNVKL 729
I HRDLK +N+L++ ++KL
Sbjct: 516 IVHRDLKPDNLLITSMGHIKL 536
>AL603888-2|CAI16562.1| 1798|Homo sapiens microtubule associated
serine/threonine kinase 2 protein.
Length = 1798
Score = 72.9 bits (171), Expect = 1e-12
Identities = 42/141 (29%), Positives = 71/141 (50%), Gaps = 1/141 (0%)
Frame = +1
Query: 310 KKIGQGSYATVHLAEYCDGSSPKRMHLACKIFDKEKAP-RDFLEKFFPRELEILTKIENP 486
K I G+Y V L + R A K +K+ R+ +++ F E +ILT ENP
Sbjct: 516 KLISNGAYGAVFLVRH----KSTRQRFAMKKINKQNLILRNQIQQAFV-ERDILTFAENP 570
Query: 487 HIIQVHSILQRGPRVFIFMRYADNGDLLDFIKRNGVVPENQAKLWFRQMASGLQYLHSKN 666
++ + + + M Y + GD +K G +P + +L+F + L+YLH+
Sbjct: 571 FVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETVLALEYLHNYG 630
Query: 667 IAHRDLKCENILLSRRFNVKL 729
I HRDLK +N+L++ ++KL
Sbjct: 631 IVHRDLKPDNLLITSMGHIKL 651
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 102,136,454
Number of Sequences: 237096
Number of extensions: 2166424
Number of successful extensions: 11359
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 10280
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 10631
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8735159784
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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