Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmte2m11
(736 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI00015B5B2E Cluster: PREDICTED: similar to ENSANGP000... 256 3e-67
UniRef50_P36957 Cluster: Dihydrolipoyllysine-residue succinyltra... 241 2e-62
UniRef50_Q4RLV1 Cluster: Chromosome 10 SCAF15019, whole genome s... 239 7e-62
UniRef50_P19262 Cluster: Dihydrolipoyllysine-residue succinyltra... 221 2e-56
UniRef50_Q9FLQ4 Cluster: 2-oxoglutarate dehydrogenase E2 subunit... 219 8e-56
UniRef50_Q1E5N3 Cluster: Dihydrolipoyllysine-residue succinyltra... 216 5e-55
UniRef50_A6SDP7 Cluster: Putative uncharacterized protein; n=1; ... 216 5e-55
UniRef50_O94681 Cluster: Probable dihydrolipoyllysine-residue su... 211 2e-53
UniRef50_Q234F3 Cluster: 2-oxoglutarate dehydrogenase, E2 compon... 210 3e-53
UniRef50_Q553V8 Cluster: Dihydrolipoamide S-succinyltransferase;... 208 8e-53
UniRef50_P0AFG7 Cluster: Dihydrolipoyllysine-residue succinyltra... 200 2e-50
UniRef50_Q63TQ8 Cluster: Dihydrolipoamide succinyltransferase co... 200 3e-50
UniRef50_Q82SG4 Cluster: SucB; dihydrolipoamide succinyltransfer... 200 4e-50
UniRef50_A5EW59 Cluster: 2-oxoglutarate dehydrogenase, E2 compon... 198 9e-50
UniRef50_Q0E0X4 Cluster: Os02g0514700 protein; n=2; Oryza sativa... 197 2e-49
UniRef50_Q7RIU5 Cluster: 2-oxoglutarate dehydrogenase, E2 compon... 197 3e-49
UniRef50_Q2UQN3 Cluster: Dihydrolipoamide succinyltransferase; n... 197 3e-49
UniRef50_Q39RZ0 Cluster: Dihydrolipoamide succinyltransferase; n... 196 4e-49
UniRef50_A5CEI9 Cluster: 2-oxoglutarate dehydrogenase, E2 compon... 196 6e-49
UniRef50_A0M5Y1 Cluster: Dihydrolipoyllysine-residue succinyltra... 195 8e-49
UniRef50_Q8DFQ0 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 194 1e-48
UniRef50_Q5P9T5 Cluster: Dihydrolipoamide acetyltransferase comp... 193 4e-48
UniRef50_Q5FS04 Cluster: Dihydrolipoamide succinyl transferase (... 193 4e-48
UniRef50_Q4Q822 Cluster: 2-oxoglutarate dehydrogenase, E2 compon... 193 4e-48
UniRef50_UPI000023F136 Cluster: hypothetical protein FG10947.1; ... 192 6e-48
UniRef50_Q98ED1 Cluster: Dihydrolipoamide succinyl transferase; ... 192 6e-48
UniRef50_A0LAA3 Cluster: 2-oxoglutarate dehydrogenase, E2 subuni... 191 1e-47
UniRef50_Q4UGK1 Cluster: Dihydrolipoamide succinyltransferase co... 191 1e-47
UniRef50_Q7ULX6 Cluster: Dihydrolipoamide succinyltransferase co... 191 2e-47
UniRef50_A6DL93 Cluster: Dihydrolipoamide acetyltransferase; n=1... 190 2e-47
UniRef50_Q1QQR6 Cluster: 2-oxoglutarate dehydrogenase, E2 compon... 190 4e-47
UniRef50_A0H458 Cluster: 2-oxoglutarate dehydrogenase, E2 compon... 189 5e-47
UniRef50_Q3SEX1 Cluster: Dihydrolipoamide succinyltransferase; n... 189 7e-47
UniRef50_Q3A0D1 Cluster: 2-oxoglutarate dehydrogenase, E2 compon... 189 7e-47
UniRef50_Q89AJ6 Cluster: Dihydrolipoyllysine-residue succinyltra... 189 7e-47
UniRef50_Q4UKI7 Cluster: Dihydrolipoyllysine-residue succinyltra... 188 9e-47
UniRef50_Q6FYD4 Cluster: Dihydrolipoyllysine-residue succinyltra... 188 1e-46
UniRef50_A0LP66 Cluster: 2-oxoglutarate dehydrogenase, E2 subuni... 188 2e-46
UniRef50_O84058 Cluster: Dihydrolipoamide Succinyltransferase; n... 187 2e-46
UniRef50_A4BP63 Cluster: 2-oxoglutarate dehydrogenase, E2 compon... 186 4e-46
UniRef50_A7AQM6 Cluster: Dihydrolipoamide succinyltransferase, p... 186 5e-46
UniRef50_Q6MC86 Cluster: Probable dihydrolipoamide S-succinyltra... 182 1e-44
UniRef50_P57389 Cluster: Dihydrolipoyllysine-residue succinyltra... 179 8e-44
UniRef50_Q057P2 Cluster: 2-oxoglutarate dehydrogenase E2 compone... 176 5e-43
UniRef50_P16263 Cluster: Dihydrolipoyllysine-residue succinyltra... 168 1e-40
UniRef50_Q49XM4 Cluster: Dihydrolipoyllysine-residue succinyltra... 165 1e-39
UniRef50_Q8R9E5 Cluster: Dihydrolipoamide acyltransferases; n=3;... 137 2e-31
UniRef50_A6WD54 Cluster: 2-oxoglutarate dehydrogenase E2 compone... 134 3e-30
UniRef50_Q9YBC6 Cluster: Pyruvate dehydrogenase complex, E2 comp... 133 5e-30
UniRef50_A4AGT3 Cluster: Putative dihydrolipoamide acyltransfera... 132 9e-30
UniRef50_Q0W153 Cluster: Pyruvate dehydrogenase complex E2, dihy... 132 9e-30
UniRef50_Q9KES1 Cluster: Dihydrolipoamide S-acetyltransferase; n... 132 1e-29
UniRef50_Q8RD59 Cluster: Dihydrolipoamide acyltransferases; n=1;... 132 1e-29
UniRef50_Q67ME8 Cluster: Branched-chain alpha-keto acid dehydrog... 130 3e-29
UniRef50_Q5KUY3 Cluster: Pyruvate dehydrogenase E2; n=2; Geobaci... 130 3e-29
UniRef50_A4A156 Cluster: Pyruvate dehydrogenase, E2 component, d... 129 6e-29
UniRef50_Q5UYG4 Cluster: Dihydrolipoamide acetyltransferase comp... 129 8e-29
UniRef50_Q749T6 Cluster: Pyruvate dehydrogenase complex E2 compo... 128 1e-28
UniRef50_A0M206 Cluster: Dihydrolipoyllysine-residue acetyltrans... 127 2e-28
UniRef50_Q3CI28 Cluster: Biotin/lipoyl attachment:Catalytic doma... 127 3e-28
UniRef50_A1SJ23 Cluster: Catalytic domain of components of vario... 126 4e-28
UniRef50_Q088Y7 Cluster: Dihydrolipoyllysine-residue succinyltra... 126 7e-28
UniRef50_A1SQB9 Cluster: Catalytic domain of components of vario... 126 7e-28
UniRef50_Q3JBP0 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 125 1e-27
UniRef50_Q1IMV8 Cluster: Dihydrolipoamide acetyltransferase; n=1... 125 1e-27
UniRef50_P37942 Cluster: Lipoamide acyltransferase component of ... 125 1e-27
UniRef50_Q3VZH8 Cluster: Biotin/lipoyl attachment:Catalytic doma... 124 2e-27
UniRef50_Q9RYB8 Cluster: 2-oxo acid dehydrogenase, E2 component;... 124 3e-27
UniRef50_Q2JA39 Cluster: Dehydrogenase subunit; n=4; Actinomycet... 124 3e-27
UniRef50_Q1Q664 Cluster: Similar to 2-oxoglutarate dehydrogenase... 124 3e-27
UniRef50_A0JUQ7 Cluster: Catalytic domain of components of vario... 124 3e-27
UniRef50_Q9KG97 Cluster: Pyruvate dehydrogenase E2; n=1; Bacillu... 123 4e-27
UniRef50_A5UTW4 Cluster: Catalytic domain of components of vario... 123 4e-27
UniRef50_Q83G30 Cluster: Dihydrolipoamide succinyltransferase co... 123 5e-27
UniRef50_Q18CC2 Cluster: E2 component of acetoin dehydrogenase e... 123 5e-27
UniRef50_Q0SJA7 Cluster: Dihydrolipoyllysine-residue succinyltra... 123 5e-27
UniRef50_Q9RXQ3 Cluster: Pyruvate dehydrogenase complex, dihydro... 122 9e-27
UniRef50_Q6MPR6 Cluster: Pyruvate dehydrogenase E2; n=1; Bdellov... 122 9e-27
UniRef50_Q48TW1 Cluster: Dihydrolipoamide acetyltransferase comp... 122 1e-26
UniRef50_Q97Y19 Cluster: Dihydrolipoamide S-acetyltransferase, c... 122 1e-26
UniRef50_A5MZI5 Cluster: PdhC; n=6; Clostridium|Rep: PdhC - Clos... 121 2e-26
UniRef50_Q49110 Cluster: Dihydrolipoyllysine-residue acetyltrans... 121 2e-26
UniRef50_A0LLM2 Cluster: Catalytic domain of components of vario... 120 3e-26
UniRef50_Q9I1M0 Cluster: Lipoamide acyltransferase component of ... 120 4e-26
UniRef50_Q5EIH5 Cluster: Dihydrolipoamide succinyltransferase co... 120 5e-26
UniRef50_A7HBV2 Cluster: Dehydrogenase complex catalytic domain;... 120 5e-26
UniRef50_Q9HN75 Cluster: Dihydrolipoamide S-acetyltransferase; n... 120 5e-26
UniRef50_Q9X6X2 Cluster: Lipoamide acyltransferase; n=3; Cystoba... 119 6e-26
UniRef50_A1UIB1 Cluster: Catalytic domain of components of vario... 119 9e-26
UniRef50_P21883 Cluster: Dihydrolipoyllysine-residue acetyltrans... 118 1e-25
UniRef50_Q67RX4 Cluster: Putative uncharacterized protein; n=1; ... 118 1e-25
UniRef50_Q65MC9 Cluster: AcoC; n=1; Bacillus licheniformis ATCC ... 118 1e-25
UniRef50_Q0SGE5 Cluster: Dihydrolipoyllysine-residue succinyltra... 118 1e-25
UniRef50_O32959 Cluster: Dihydrolipoamide succinyltransferase; n... 117 3e-25
UniRef50_Q1AZ52 Cluster: Catalytic domain of components of vario... 117 3e-25
UniRef50_Q14PD7 Cluster: Putative dihydrolipoyllysine-residue ac... 117 3e-25
UniRef50_Q9PKE7 Cluster: Pyruvate dehydrogenase, E2 component, d... 117 3e-25
UniRef50_Q67SE5 Cluster: Pyruvate dehydrogenase E2; n=1; Symbiob... 117 3e-25
UniRef50_P65634 Cluster: Dihydrolipoyllysine-residue succinyltra... 117 3e-25
UniRef50_O31550 Cluster: Dihydrolipoyllysine-residue acetyltrans... 117 3e-25
UniRef50_O84249 Cluster: Dihydrolipoamide Acetyltransferase; n=7... 116 8e-25
UniRef50_A4XEQ9 Cluster: Catalytic domain of components of vario... 116 8e-25
UniRef50_Q5ZVD7 Cluster: Pyruvate dehydrogenase E2 component; n=... 115 1e-24
UniRef50_A6DTS5 Cluster: Pyruvate dehydrogenase complex , E2 com... 115 1e-24
UniRef50_A0JZU9 Cluster: Catalytic domain of components of vario... 115 1e-24
UniRef50_A0LQU7 Cluster: Catalytic domain of components of vario... 115 1e-24
UniRef50_Q92HK7 Cluster: Dihydrolipoyllysine-residue acetyltrans... 115 1e-24
UniRef50_Q92BY1 Cluster: Lin1411 protein; n=15; Bacillales|Rep: ... 114 2e-24
UniRef50_Q8YDW4 Cluster: DIHYDROLIPOAMIDE ACETYLTRANSFERASE COMP... 114 2e-24
UniRef50_Q73FZ4 Cluster: Pyruvate dehydrogenase complex, E2 comp... 114 2e-24
UniRef50_Q47KD8 Cluster: Pyruvate dehydrogenase complex, E2 comp... 114 2e-24
UniRef50_A6GB59 Cluster: Alpha keto acid dehydrogenase complex, ... 114 2e-24
UniRef50_A3U7C0 Cluster: Lipoamide acyltransferase component of ... 114 2e-24
UniRef50_Q98PG1 Cluster: DIHYDROLIPOAMIDE ACETYLTRANSFERASE COMP... 113 3e-24
UniRef50_A6C4P4 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 113 3e-24
UniRef50_Q2S4D4 Cluster: 2-oxo acid dehydrogenases acyltransfera... 113 4e-24
UniRef50_Q7D716 Cluster: 2-oxoisovalerate dehydrogenase E2 compo... 113 4e-24
UniRef50_A3WJV9 Cluster: Apha keto acid dehydrogenase complex, E... 113 4e-24
UniRef50_A1ZE93 Cluster: Pyruvate dehydrogenase complex dihydrol... 113 4e-24
UniRef50_A0LSF1 Cluster: Catalytic domain of components of vario... 113 4e-24
UniRef50_Q6FDE9 Cluster: Dihydrolipoamide acetyltransferase; n=3... 112 1e-23
UniRef50_A4WK39 Cluster: Catalytic domain of components of vario... 112 1e-23
UniRef50_Q19749 Cluster: Dihydrolipoyllysine-residue acetyltrans... 112 1e-23
UniRef50_P09062 Cluster: Lipoamide acyltransferase component of ... 112 1e-23
UniRef50_Q4L6L6 Cluster: Branched-chain alpha-keto acid dehydrog... 111 1e-23
UniRef50_A3HTS0 Cluster: 2-oxo acid dehydrogenases acyltransfera... 111 1e-23
UniRef50_Q8CX89 Cluster: Pyruvate dehydrogenase E2; n=4; Bacilla... 111 2e-23
UniRef50_Q74AE1 Cluster: Dehydrogenase complex E2 component, dih... 111 2e-23
UniRef50_Q1IIF0 Cluster: Dihydrolipoamide S-succinyltransferase;... 111 2e-23
UniRef50_Q0RVL0 Cluster: Dihydrolipoyllysine-residue succinyltra... 111 2e-23
UniRef50_A6TMP1 Cluster: Catalytic domain of components of vario... 111 2e-23
UniRef50_A0K281 Cluster: Catalytic domain of components of vario... 111 2e-23
UniRef50_Q5Z123 Cluster: Putative branched-chain alpha-keto acid... 111 2e-23
UniRef50_Q1VYW1 Cluster: Dihydrolipoyllysine-residue acetyltrans... 111 2e-23
UniRef50_A2TU26 Cluster: Lipoamide acyltransferase component of ... 111 2e-23
UniRef50_Q8AB01 Cluster: Lipoamide acyltransferase component of ... 110 3e-23
UniRef50_Q1YS54 Cluster: Dihydrolipoamide acetyltransferase; n=1... 110 3e-23
UniRef50_Q03Y73 Cluster: Acetoin/pyruvate dehydrogenase complex,... 110 3e-23
UniRef50_A1SQ65 Cluster: Catalytic domain of components of vario... 110 3e-23
UniRef50_A1R9E2 Cluster: Pyruvate dehydrogenase E2; n=2; Actinom... 110 3e-23
UniRef50_Q6A613 Cluster: Dihydrolipoamide acetyltransferase comp... 110 4e-23
UniRef50_Q2GCH9 Cluster: Pyruvate dehydrogenase complex, E2 comp... 110 4e-23
UniRef50_Q14Q97 Cluster: Putative uncharacterized protein; n=1; ... 110 4e-23
UniRef50_A6EAZ4 Cluster: Dihydrolipoyllysine-residue acetyltrans... 110 4e-23
UniRef50_Q5UWH1 Cluster: Dihydrolipoamide S-acetyltransferase co... 110 4e-23
UniRef50_Q6ABX9 Cluster: Dihydrolipoyllysine-residue acetyltrans... 109 5e-23
UniRef50_Q2S152 Cluster: Dihydrolipoyllysine-residue acetyltrans... 109 7e-23
UniRef50_Q8ZUR6 Cluster: Pyruvate dehydrogenase E2; n=1; Pyrobac... 109 7e-23
UniRef50_Q2J8A0 Cluster: Dehydrogenase subunit; n=9; Actinobacte... 108 1e-22
UniRef50_A1ZHD0 Cluster: Dihydrolipoyllysine-residue succinyltra... 108 1e-22
UniRef50_Q1GTH9 Cluster: Catalytic domain of components of vario... 107 2e-22
UniRef50_A0YCP9 Cluster: Pyruvate dehydrogenase complex dihydrol... 107 2e-22
UniRef50_Q2JGZ2 Cluster: Dehydrogenase subunit; n=1; Frankia sp.... 107 3e-22
UniRef50_Q9RPS3 Cluster: Dihydrolipoamide acyltransferase; n=3; ... 107 3e-22
UniRef50_A6UGY8 Cluster: Dihydrolipoyllysine-residue succinyltra... 107 3e-22
UniRef50_P35489 Cluster: Dihydrolipoyllysine-residue acetyltrans... 107 3e-22
UniRef50_Q9FC63 Cluster: Putative acyltransferase; n=1; Streptom... 107 4e-22
UniRef50_Q8F4N2 Cluster: Dihydrolipoamide acetyltransferase comp... 107 4e-22
UniRef50_Q97CK2 Cluster: Pyruvate dehydrogenase E2 / dihydrolipo... 107 4e-22
UniRef50_Q1AT73 Cluster: Catalytic domain of components of vario... 106 5e-22
UniRef50_Q0LND0 Cluster: Dihydrolipoamide S-succinyltransferase;... 106 5e-22
UniRef50_A3UGB6 Cluster: Dihydrolipoamide acetyltransferase; n=2... 106 5e-22
UniRef50_Q0WQF7 Cluster: Dihydrolipoyllysine-residue acetyltrans... 106 6e-22
UniRef50_Q5L233 Cluster: Pyruvate dehydrogenase E2; n=2; Geobaci... 105 9e-22
UniRef50_UPI0000DB7177 Cluster: PREDICTED: similar to Pyruvate d... 105 1e-21
UniRef50_Q63HZ8 Cluster: Lipoamide acyltransferase component of ... 105 1e-21
UniRef50_Q1NYU2 Cluster: Dihydrolipoamide acyltransferase E2 com... 105 1e-21
UniRef50_A7HHV9 Cluster: Pyruvate dehydrogenase complex dihydrol... 105 1e-21
UniRef50_A0PU60 Cluster: Dihydrolipoamide S-acetyltransferase E2... 105 1e-21
UniRef50_A0CWR1 Cluster: Chromosome undetermined scaffold_3, who... 105 1e-21
UniRef50_P06959 Cluster: Dihydrolipoyllysine-residue acetyltrans... 105 1e-21
UniRef50_Q2GI07 Cluster: Pyruvate dehydrogenase complex, E2 comp... 104 3e-21
UniRef50_Q0LRZ3 Cluster: Dihydrolipoamide acetyltransferase, lon... 104 3e-21
UniRef50_A5IXN4 Cluster: Dihydrolipoamide acetyltransferase comp... 104 3e-21
UniRef50_Q7WED2 Cluster: Probable 2-oxo acid dehydrogenases acyl... 103 3e-21
UniRef50_Q39ET0 Cluster: Dihydrolipoamide acetyltransferase; n=4... 103 3e-21
UniRef50_Q2B858 Cluster: Pyruvate dehydrogenase E2; n=1; Bacillu... 103 5e-21
UniRef50_Q1V1J3 Cluster: Dihydrolipoamide S-acetyltransferase; n... 103 6e-21
UniRef50_A3VK82 Cluster: Putative uncharacterized protein; n=1; ... 103 6e-21
UniRef50_Q6PLQ2 Cluster: Dihydrolipoamide S-acetyltransferase; n... 103 6e-21
UniRef50_P45118 Cluster: Dihydrolipoyllysine-residue acetyltrans... 102 8e-21
UniRef50_Q820A3 Cluster: AceF; dihydrolipoamide acetyltransferas... 102 1e-20
UniRef50_P10802 Cluster: Dihydrolipoyllysine-residue acetyltrans... 102 1e-20
UniRef50_Q6KH63 Cluster: Pyruvate dehydrogenase E2 component dih... 101 1e-20
UniRef50_Q4FS31 Cluster: Dihydrolipoyllysine acetyltransferase c... 101 1e-20
UniRef50_A6W003 Cluster: Catalytic domain of components of vario... 101 1e-20
UniRef50_A6GG26 Cluster: Dihydrolipoyllysine-residue acetyltrans... 101 1e-20
UniRef50_O45279 Cluster: Putative uncharacterized protein; n=2; ... 101 1e-20
UniRef50_Q59638 Cluster: Dihydrolipoyllysine-residue acetyltrans... 101 1e-20
UniRef50_Q9PJZ6 Cluster: 2-oxo acid dehydrogenase, E2 component,... 101 2e-20
UniRef50_Q8D2N2 Cluster: AceF protein; n=1; Wigglesworthia gloss... 101 2e-20
UniRef50_Q3WAF9 Cluster: Biotin/lipoyl attachment:Catalytic doma... 101 2e-20
UniRef50_O59816 Cluster: Dihydrolipoyllysine-residue acetyltrans... 101 2e-20
UniRef50_Q1LSX2 Cluster: Pyruvate dehydrogenase complex, E2 comp... 101 2e-20
UniRef50_Q4QJI5 Cluster: Dihydrolipoamide branched chain transac... 101 2e-20
UniRef50_Q98FT5 Cluster: Dihydrolipoamide acetyltransferase homo... 100 3e-20
UniRef50_Q08V09 Cluster: Pyruvate dehydrogenase complex dihydrol... 100 3e-20
UniRef50_A5V4B2 Cluster: Catalytic domain of components of vario... 100 3e-20
UniRef50_A3WC78 Cluster: Pyruvate dehydrogenase E2 component; n=... 100 3e-20
UniRef50_Q6L1M0 Cluster: Dihydrolipoamide acetyltransferase comp... 100 3e-20
UniRef50_Q8EVQ0 Cluster: Dihydrolipoamide acetyltransferase of p... 100 4e-20
UniRef50_Q6F713 Cluster: Dihydrolipoamide S-acetyltransferase, E... 100 4e-20
UniRef50_A7BC27 Cluster: Putative uncharacterized protein; n=1; ... 100 4e-20
UniRef50_A3CMZ5 Cluster: Dihydrolipoamide acetyl transferase, E2... 100 4e-20
UniRef50_A0H5V3 Cluster: Dihydrolipoamide S-succinyltransferase;... 100 4e-20
UniRef50_A4RXN8 Cluster: Predicted protein; n=3; cellular organi... 100 4e-20
UniRef50_P10515 Cluster: Dihydrolipoyllysine-residue acetyltrans... 100 4e-20
UniRef50_Q8RBW8 Cluster: Dihydrolipoamide acyltransferases; n=1;... 100 7e-20
UniRef50_Q5P915 Cluster: Pyruvate dehydrogenase multienzyme comp... 100 7e-20
UniRef50_Q0VRX7 Cluster: Pyruvate dehydrogenase, E2 component; n... 100 7e-20
UniRef50_A5UU13 Cluster: Dihydrolipoyllysine-residue succinyltra... 100 7e-20
UniRef50_A1KCD0 Cluster: Putative uncharacterized protein; n=1; ... 100 7e-20
UniRef50_A7THD4 Cluster: Putative uncharacterized protein; n=1; ... 100 7e-20
UniRef50_A4XHV3 Cluster: Catalytic domain of components of vario... 99 1e-19
UniRef50_Q57Z16 Cluster: Dihydrolipoamide branched chain transac... 98 2e-19
UniRef50_A1SYC2 Cluster: Dihydrolipoamide dehydrogenase E3 compo... 98 2e-19
UniRef50_O66119 Cluster: Dihydrolipoyllysine-residue acetyltrans... 98 2e-19
UniRef50_A4CQ51 Cluster: Lipoamide acyltransferase component of ... 97 3e-19
UniRef50_Q54TR7 Cluster: Dihydrolipoyl transacylase; n=1; Dictyo... 97 3e-19
UniRef50_Q5KIM3 Cluster: Dihydrolipoyllysine-residue acetyltrans... 97 3e-19
UniRef50_Q6KCM0 Cluster: Dihydrolipoyl transacetylase; n=1; Eugl... 97 4e-19
UniRef50_Q1EGH6 Cluster: Pyruvate dehydrogenase E2 subunit; n=1;... 97 5e-19
UniRef50_O00330 Cluster: Pyruvate dehydrogenase protein X compon... 97 5e-19
UniRef50_Q4L1A5 Cluster: Dihydrolipoamide acetyltransferase; n=2... 96 9e-19
UniRef50_Q13GQ6 Cluster: Dihydrolipoamide acyltransferase (E2) c... 96 9e-19
UniRef50_Q9M724 Cluster: Branched chain alpha-keto acid dehydrog... 96 9e-19
UniRef50_P75392 Cluster: Dihydrolipoyllysine-residue acetyltrans... 96 9e-19
UniRef50_Q68FJ5 Cluster: MGC86218 protein; n=3; Tetrapoda|Rep: M... 95 1e-18
UniRef50_Q7NB00 Cluster: AceF; n=1; Mycoplasma gallisepticum|Rep... 95 1e-18
UniRef50_A2WZU5 Cluster: Putative uncharacterized protein; n=2; ... 95 1e-18
UniRef50_Q9XYS5 Cluster: Dihydrolipoyl dehydrogenase-binding pro... 95 1e-18
UniRef50_P12695 Cluster: Dihydrolipoyllysine-residue acetyltrans... 95 1e-18
UniRef50_A3SYT7 Cluster: Acetoin dehydrogenase E2 component; n=2... 95 2e-18
UniRef50_Q1EGH5 Cluster: Pyruvate dehydrogenase E2 subunit; n=3;... 95 2e-18
UniRef50_UPI00015A4520 Cluster: UPI00015A4520 related cluster; n... 94 3e-18
UniRef50_Q8EJN8 Cluster: Pyruvate dehydrogenase complex, E2 comp... 94 3e-18
UniRef50_P36413 Cluster: Dihydrolipoyllysine-residue acetyltrans... 94 3e-18
UniRef50_UPI0000E4A22B Cluster: PREDICTED: similar to pyruvate d... 93 5e-18
UniRef50_Q5WE92 Cluster: Acetoin dehydrogenase E2 component; n=1... 93 5e-18
UniRef50_P20285 Cluster: Dihydrolipoyllysine-residue acetyltrans... 93 5e-18
UniRef50_Q057U1 Cluster: Pyruvate dehydrogenase E2 component; n=... 93 8e-18
UniRef50_A4SZ52 Cluster: Catalytic domain of components of vario... 93 8e-18
UniRef50_Q15U82 Cluster: Catalytic domain of components of vario... 92 1e-17
UniRef50_A5CVP1 Cluster: Pyruvate dehydrogenase complex E2 compo... 92 1e-17
UniRef50_Q6C806 Cluster: Similar to tr|Q9VXY3 Drosophila melanog... 91 2e-17
UniRef50_Q4WQ92 Cluster: 2-oxo acid dehydrogenases acyltransfera... 91 2e-17
UniRef50_UPI000038D51F Cluster: COG0508: Pyruvate/2-oxoglutarate... 91 3e-17
UniRef50_A0NRH8 Cluster: Branched-chain alpha-keto acid dehydrog... 91 3e-17
UniRef50_Q8RWN9 Cluster: Dihydrolipoyllysine-residue acetyltrans... 91 3e-17
UniRef50_A0Z3Y6 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 90 6e-17
UniRef50_Q0UN70 Cluster: Putative uncharacterized protein; n=1; ... 90 6e-17
UniRef50_UPI000150A9DD Cluster: pyruvate dehydrogenase complex d... 89 1e-16
UniRef50_UPI0000ECB9E1 Cluster: Apoptosis inhibitor 5 (API-5).; ... 89 1e-16
UniRef50_A6PJ30 Cluster: Catalytic domain of components of vario... 89 1e-16
UniRef50_A7SJI4 Cluster: Predicted protein; n=2; Nematostella ve... 89 1e-16
UniRef50_A4S3G1 Cluster: Predicted protein; n=2; Ostreococcus|Re... 89 1e-16
UniRef50_Q9R9N3 Cluster: Dihydrolipoyllysine-residue acetyltrans... 89 1e-16
UniRef50_Q89AQ9 Cluster: Dihydrolipoyllysine-residue acetyltrans... 89 1e-16
UniRef50_Q23VX7 Cluster: 2-oxo acid dehydrogenases acyltransfera... 88 2e-16
UniRef50_Q4Q1F5 Cluster: Dihydrolipoamide acetyltransferase, put... 87 3e-16
UniRef50_UPI0000D56122 Cluster: PREDICTED: similar to Lipoamide ... 87 4e-16
UniRef50_A1RJV4 Cluster: Catalytic domain of components of vario... 87 4e-16
UniRef50_Q2UJZ9 Cluster: Dihydrolipoamide transacylase; n=9; Eur... 87 4e-16
UniRef50_Q9VXY3 Cluster: CG5599-PA; n=4; Diptera|Rep: CG5599-PA ... 86 1e-15
UniRef50_P11182 Cluster: Lipoamide acyltransferase component of ... 85 1e-15
UniRef50_Q8D6Q5 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 85 2e-15
UniRef50_A0D1R4 Cluster: Chromosome undetermined scaffold_34, wh... 84 4e-15
UniRef50_A0G738 Cluster: Catalytic domain of components of vario... 83 5e-15
UniRef50_A4BTC4 Cluster: Dihydrolipoamide acetyltransferase; n=2... 83 7e-15
UniRef50_Q7RS62 Cluster: Plasmodium vivax PV1H14105_P; n=8; Plas... 83 9e-15
UniRef50_Q59658 Cluster: Dihydrolipoamide acetyltransferase; n=3... 81 2e-14
UniRef50_Q5DAR0 Cluster: SJCHGC04873 protein; n=1; Schistosoma j... 81 2e-14
UniRef50_A6RRC1 Cluster: Putative uncharacterized protein; n=2; ... 81 3e-14
UniRef50_A4RMY6 Cluster: Putative uncharacterized protein; n=1; ... 79 1e-13
UniRef50_Q5HKM0 Cluster: Acetoin dehydrogenase, E2 component, di... 79 1e-13
UniRef50_Q7SH25 Cluster: Putative uncharacterized protein NCU027... 78 2e-13
UniRef50_A4AIF6 Cluster: Dihydrolipoamide acetyltransferase; n=1... 78 3e-13
UniRef50_A7AT28 Cluster: Lipoamide acyltransferase component of ... 77 5e-13
UniRef50_A1FTV4 Cluster: Catalytic domain of components of vario... 77 6e-13
UniRef50_A0J2S5 Cluster: Catalytic domain of components of vario... 77 6e-13
UniRef50_A7Q7E8 Cluster: Chromosome chr18 scaffold_59, whole gen... 76 8e-13
UniRef50_Q83DQ8 Cluster: Dehydrogenase, E2 component, acyltransf... 76 1e-12
UniRef50_Q8PQ85 Cluster: Dihydrolipoamide acyltransferase; n=7; ... 75 2e-12
UniRef50_P96104 Cluster: Dihydrolipoyl transacetylase and lipoam... 75 2e-12
UniRef50_A6PBA2 Cluster: Catalytic domain of components of vario... 75 2e-12
UniRef50_A1T0M1 Cluster: Pyruvate dehydrogenase complex, E2 comp... 75 2e-12
UniRef50_A0JS87 Cluster: Catalytic domain of components of vario... 75 2e-12
UniRef50_Q55AS9 Cluster: Pyruvate dehydrogenase complex, compone... 75 2e-12
UniRef50_A6Q8W6 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 74 3e-12
UniRef50_Q5ZV80 Cluster: Dihydrolipoamide acetyltransferase; n=5... 74 4e-12
UniRef50_Q7VDH5 Cluster: Dihydrolipoamide S-acetyltransferase; n... 73 6e-12
UniRef50_UPI0000DB75B7 Cluster: PREDICTED: similar to Lipoamide ... 73 1e-11
UniRef50_Q0A5F2 Cluster: Catalytic domain of components of vario... 72 1e-11
UniRef50_Q12FH2 Cluster: Catalytic domain of components of vario... 71 2e-11
UniRef50_A1UBW5 Cluster: Catalytic domain of components of vario... 71 2e-11
UniRef50_Q9SQI8 Cluster: Dihydrolipoamide S-acetyltransferase; n... 71 2e-11
UniRef50_Q7NHG8 Cluster: Dihydrolipoamide S-acetyltransferase; n... 71 4e-11
UniRef50_Q6AIE3 Cluster: Probable pyruvate dehydrogenase, E2 com... 69 9e-11
UniRef50_Q9K3H2 Cluster: Putative acyltransferase; n=1; Streptom... 69 1e-10
UniRef50_A3BC27 Cluster: Putative uncharacterized protein; n=2; ... 69 2e-10
UniRef50_Q7MB23 Cluster: Similar to peptide synthetase. Putative... 66 6e-10
UniRef50_Q3SL16 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 66 6e-10
UniRef50_A2WKX8 Cluster: Putative uncharacterized protein; n=1; ... 66 8e-10
UniRef50_A5V538 Cluster: Catalytic domain of components of vario... 64 3e-09
UniRef50_A6FIQ1 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 64 3e-09
UniRef50_Q4U9K9 Cluster: 2-oxoglutarate dehydrogenase complex su... 62 1e-08
UniRef50_Q7RFX9 Cluster: Putative dihydrolipoamide S-acetyltrans... 62 1e-08
UniRef50_Q01VQ8 Cluster: 2-oxoglutarate dehydrogenase, E1 subuni... 61 3e-08
UniRef50_Q8NRC3 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 60 4e-08
UniRef50_Q5VGY2 Cluster: Dihydrolipoamide S-acetyltransferase; n... 59 1e-07
UniRef50_Q2S3D2 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 59 1e-07
UniRef50_A7BE99 Cluster: Putative uncharacterized protein; n=1; ... 57 5e-07
UniRef50_A6Q9K5 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 56 1e-06
UniRef50_A0Z5N6 Cluster: Pyruvate dehydrogenase complex, E2 comp... 56 1e-06
UniRef50_Q9KBS7 Cluster: BH1847 protein; n=1; Bacillus haloduran... 55 2e-06
UniRef50_Q4P9L5 Cluster: Putative uncharacterized protein; n=1; ... 53 8e-06
UniRef50_A6Q3I4 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 51 3e-05
UniRef50_UPI0000E48C7F Cluster: PREDICTED: similar to transacyla... 51 3e-05
UniRef50_A3CFJ5 Cluster: Putative uncharacterized protein; n=2; ... 50 6e-05
UniRef50_Q7TQ85 Cluster: Ac1164; n=1; Rattus norvegicus|Rep: Ac1... 44 0.003
UniRef50_Q3W1D8 Cluster: Catalytic domain of components of vario... 44 0.005
UniRef50_Q7NLM9 Cluster: Gll1092 protein; n=1; Gloeobacter viola... 43 0.007
UniRef50_UPI00006CB607 Cluster: hypothetical protein TTHERM_0044... 42 0.012
UniRef50_A6TN70 Cluster: Catalytic domain of components of vario... 42 0.021
UniRef50_A4F1Y4 Cluster: Dihydrolopoamide acyltransferase; n=1; ... 42 0.021
UniRef50_A3TFL4 Cluster: Putative uncharacterized protein; n=1; ... 41 0.027
UniRef50_Q1QQR8 Cluster: Putative uncharacterized protein; n=1; ... 40 0.063
UniRef50_UPI000038CE95 Cluster: COG0508: Pyruvate/2-oxoglutarate... 39 0.15
UniRef50_Q1D6S2 Cluster: 2-oxo acid dehydrogenase acyltransferas... 38 0.26
UniRef50_O61646 Cluster: Splicing factor SRp54; n=8; Endopterygo... 37 0.59
UniRef50_A7MGN4 Cluster: Putative uncharacterized protein; n=2; ... 36 0.78
UniRef50_P09269 Cluster: Transcriptional transactivator IE4; n=3... 36 1.4
UniRef50_Q3LVF5 Cluster: TO119-1rc; n=1; Taraxacum officinale|Re... 35 1.8
UniRef50_Q2NXC9 Cluster: Putative uncharacterized protein XOO429... 35 2.4
UniRef50_A0C618 Cluster: Chromosome undetermined scaffold_151, w... 35 2.4
UniRef50_A3DKD8 Cluster: Putative uncharacterized protein; n=1; ... 34 4.2
UniRef50_Q86YZ3 Cluster: Hornerin; n=8; Theria|Rep: Hornerin - H... 34 4.2
UniRef50_UPI0000DB78AB Cluster: PREDICTED: hypothetical protein;... 33 5.5
UniRef50_Q1D4C4 Cluster: Putative uncharacterized protein; n=1; ... 33 5.5
UniRef50_A6FUH5 Cluster: Putative uncharacterized protein; n=1; ... 33 5.5
UniRef50_Q9SIT8 Cluster: Putative uncharacterized protein At2g13... 33 7.3
UniRef50_A6SI95 Cluster: Predicted protein; n=1; Botryotinia fuc... 33 7.3
UniRef50_A4R9H3 Cluster: Predicted protein; n=1; Magnaporthe gri... 33 7.3
UniRef50_Q3JRC8 Cluster: Putative uncharacterized protein; n=5; ... 33 9.6
UniRef50_A4RTA5 Cluster: Predicted protein; n=1; Ostreococcus lu... 33 9.6
UniRef50_Q9YA80 Cluster: Putative uncharacterized protein; n=1; ... 33 9.6
UniRef50_P40376 Cluster: cAMP-dependent protein kinase catalytic... 33 9.6
>UniRef50_UPI00015B5B2E Cluster: PREDICTED: similar to
ENSANGP00000010144; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ENSANGP00000010144 - Nasonia
vitripennis
Length = 483
Score = 256 bits (628), Expect = 3e-67
Identities = 116/151 (76%), Positives = 139/151 (92%)
Frame = +3
Query: 3 VIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIE 182
VI+ +I+YRDYVDISVAVATPKGLVVPV+R+V+N +A+IE+ +A + +KAR GK+++E
Sbjct: 333 VIDGTDIVYRDYVDISVAVATPKGLVVPVLRSVENKNFAEIEIAMAAVGDKARKGKISVE 392
Query: 183 EMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTY 362
+MDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHG+F+RPIA+ GQVVIRPMMY+ALTY
Sbjct: 393 DMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGVFDRPIAVKGQVVIRPMMYVALTY 452
Query: 363 DHRLIDGREAVLFLRKIKEGVEDPATIVAGL 455
DHRLIDGREAV+FLRKIK+ VEDP I+AGL
Sbjct: 453 DHRLIDGREAVMFLRKIKDAVEDPRIILAGL 483
>UniRef50_P36957 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex, mitochondrial precursor; n=48;
Fungi/Metazoa group|Rep: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex, mitochondrial precursor - Homo
sapiens (Human)
Length = 453
Score = 241 bits (589), Expect = 2e-62
Identities = 111/146 (76%), Positives = 127/146 (86%)
Frame = +3
Query: 18 EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGG 197
E++YRDY+DISVAVATP+GLVVPVIRNV+ M +ADIE TI L EKAR +L IE+MDGG
Sbjct: 308 EVVYRDYIDISVAVATPRGLVVPVIRNVEAMNFADIERTITELGEKARKNELAIEDMDGG 367
Query: 198 TFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLI 377
TFTISNGGVFGSL GTPIINPPQSAILGMHGIF+RP+A+ G+V +RPMMY+ALTYDHRLI
Sbjct: 368 TFTISNGGVFGSLFGTPIINPPQSAILGMHGIFDRPVAIGGKVEVRPMMYVALTYDHRLI 427
Query: 378 DGREAVLFLRKIKEGVEDPATIVAGL 455
DGREAV FLRKIK VEDP ++ L
Sbjct: 428 DGREAVTFLRKIKAAVEDPRVLLLDL 453
>UniRef50_Q4RLV1 Cluster: Chromosome 10 SCAF15019, whole genome
shotgun sequence; n=5; Bilateria|Rep: Chromosome 10
SCAF15019, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 461
Score = 239 bits (584), Expect = 7e-62
Identities = 112/143 (78%), Positives = 125/143 (87%)
Frame = +3
Query: 18 EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGG 197
EI+YRDYVDISVAVATPKGLVVPVIRNV+ M +ADIE I L EKAR +L +E+MDGG
Sbjct: 316 EIVYRDYVDISVAVATPKGLVVPVIRNVEGMNFADIEKAINLLGEKARKNELAVEDMDGG 375
Query: 198 TFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLI 377
TFTISNGGVFGS+ GTPIINPPQSAILGMHGIFERP+A+ G+V IRPMMY+ALTYDHRLI
Sbjct: 376 TFTISNGGVFGSMFGTPIINPPQSAILGMHGIFERPVAIGGKVEIRPMMYVALTYDHRLI 435
Query: 378 DGREAVLFLRKIKEGVEDPATIV 446
DGREAV FLRKIK VEDP ++
Sbjct: 436 DGREAVTFLRKIKSVVEDPRVLL 458
>UniRef50_P19262 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex, mitochondrial precursor; n=21;
Ascomycota|Rep: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex, mitochondrial precursor -
Saccharomyces cerevisiae (Baker's yeast)
Length = 463
Score = 221 bits (539), Expect = 2e-56
Identities = 99/143 (69%), Positives = 122/143 (85%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEE 185
IE ++I+YRDY DISVAVATPKGLV PV+RN ++++ DIE I L+ KAR GKLT+E+
Sbjct: 315 IEGDQIVYRDYTDISVAVATPKGLVTPVVRNAESLSVLDIENEIVRLSHKARDGKLTLED 374
Query: 186 MDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYD 365
M GGTFTISNGGVFGSL GTPIIN PQ+A+LG+HG+ ERP+ +NGQ+V RPMMY+ALTYD
Sbjct: 375 MTGGTFTISNGGVFGSLYGTPIINSPQTAVLGLHGVKERPVTVNGQIVSRPMMYLALTYD 434
Query: 366 HRLIDGREAVLFLRKIKEGVEDP 434
HRL+DGREAV FL+ +KE +EDP
Sbjct: 435 HRLLDGREAVTFLKTVKELIEDP 457
>UniRef50_Q9FLQ4 Cluster: 2-oxoglutarate dehydrogenase E2 subunit;
n=15; Magnoliophyta|Rep: 2-oxoglutarate dehydrogenase E2
subunit - Arabidopsis thaliana (Mouse-ear cress)
Length = 464
Score = 219 bits (534), Expect = 8e-56
Identities = 102/148 (68%), Positives = 124/148 (83%)
Frame = +3
Query: 3 VIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIE 182
VI+ ++IIYRDYVDIS+AV T KGLVVPVIR+ M +ADIE TI GLA+KA G ++I+
Sbjct: 314 VIDGDDIIYRDYVDISIAVGTSKGLVVPVIRDADKMNFADIEKTINGLAKKATEGTISID 373
Query: 183 EMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTY 362
EM GG+FT+SNGGV+GSL+ TPIINPPQSAILGMH I +RP+ + G VV RPMMY+ALTY
Sbjct: 374 EMAGGSFTVSNGGVYGSLISTPIINPPQSAILGMHSIVQRPMVVGGSVVPRPMMYVALTY 433
Query: 363 DHRLIDGREAVLFLRKIKEGVEDPATIV 446
DHRLIDGREAV FLR+IK+ VEDP ++
Sbjct: 434 DHRLIDGREAVYFLRRIKDVVEDPQRLL 461
>UniRef50_Q1E5N3 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex, mitochondrial; n=8; Dikarya|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex,
mitochondrial - Coccidioides immitis
Length = 484
Score = 216 bits (527), Expect = 5e-55
Identities = 101/144 (70%), Positives = 119/144 (82%)
Frame = +3
Query: 21 IIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGT 200
I+YRDYVDISVAVAT KGLV PV+RNV+NM IE IA L +KAR KLTIE+M GGT
Sbjct: 341 IVYRDYVDISVAVATEKGLVTPVVRNVENMDLTTIEKAIADLGQKARDNKLTIEDMAGGT 400
Query: 201 FTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLID 380
FTISNGGVFGSLMGTPIIN PQ+ +LG+H I RP+A+NG+V IRPMMY+ALTYDHRL+D
Sbjct: 401 FTISNGGVFGSLMGTPIINLPQTGVLGLHAIKNRPVAVNGKVEIRPMMYLALTYDHRLLD 460
Query: 381 GREAVLFLRKIKEGVEDPATIVAG 452
GREAV FL ++KE +EDP ++ G
Sbjct: 461 GREAVTFLVRVKEFIEDPRRMLLG 484
>UniRef50_A6SDP7 Cluster: Putative uncharacterized protein; n=1;
Botryotinia fuckeliana B05.10|Rep: Putative
uncharacterized protein - Botryotinia fuckeliana B05.10
Length = 370
Score = 216 bits (527), Expect = 5e-55
Identities = 100/138 (72%), Positives = 118/138 (85%)
Frame = +3
Query: 21 IIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGT 200
I+YRDYVDISVAVAT KGLV PV+RN ++M IE TIA L +KAR KLTIE+M GGT
Sbjct: 228 IVYRDYVDISVAVATEKGLVTPVVRNTESMDLVGIEKTIADLGKKARDNKLTIEDMAGGT 287
Query: 201 FTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLID 380
FTISNGGVFGSLMGTPIIN PQ+A+LG+H I ++P+ +NGQ+VIRPMMY+ALTYDHRL+D
Sbjct: 288 FTISNGGVFGSLMGTPIINLPQTAVLGLHAIKDKPVVVNGQIVIRPMMYLALTYDHRLLD 347
Query: 381 GREAVLFLRKIKEGVEDP 434
GREAV FL K+KE +EDP
Sbjct: 348 GREAVQFLVKVKEYIEDP 365
>UniRef50_O94681 Cluster: Probable dihydrolipoyllysine-residue
succinyltransferase component of 2-oxoglutarate
dehydrogenase complex, mitochondrial precursor; n=1;
Schizosaccharomyces pombe|Rep: Probable
dihydrolipoyllysine-residue succinyltransferase
component of 2-oxoglutarate dehydrogenase complex,
mitochondrial precursor - Schizosaccharomyces pombe
(Fission yeast)
Length = 452
Score = 211 bits (515), Expect = 2e-53
Identities = 95/142 (66%), Positives = 118/142 (83%)
Frame = +3
Query: 21 IIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGT 200
++YRD+ D+S+AVATPKGLV PVIRN ++M+ +IE IA L KAR GKL IE+M GT
Sbjct: 309 LVYRDFCDLSIAVATPKGLVTPVIRNAESMSLLEIESAIATLGSKARAGKLAIEDMASGT 368
Query: 201 FTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLID 380
FTISNGG+FGSL GTPIIN PQ+A+LG+H I ERP+ +NGQVV RPMMY+ALTYDHR++D
Sbjct: 369 FTISNGGIFGSLYGTPIINLPQTAVLGLHAIKERPVVINGQVVPRPMMYLALTYDHRMVD 428
Query: 381 GREAVLFLRKIKEGVEDPATIV 446
GREAV FLR +KE +EDPA ++
Sbjct: 429 GREAVTFLRLVKEYIEDPAKML 450
>UniRef50_Q234F3 Cluster: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase family
protein; n=1; Tetrahymena thermophila SB210|Rep:
2-oxoglutarate dehydrogenase, E2 component,
dihydrolipoamide succinyltransferase family protein -
Tetrahymena thermophila SB210
Length = 564
Score = 210 bits (513), Expect = 3e-53
Identities = 95/148 (64%), Positives = 119/148 (80%)
Frame = +3
Query: 3 VIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIE 182
VI+ EI+YR+YVDISVAVATP GL+VPV+RN +NM++AD+E I L K + G +T+E
Sbjct: 414 VIDGKEIVYRNYVDISVAVATPTGLMVPVLRNTENMSFADVEREIIRLGNKGKEGSITVE 473
Query: 183 EMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTY 362
+M GGTFTISNGG +GSL G PI+NPPQSAILGMH + RP+ Q+V RPMMY+ALTY
Sbjct: 474 DMVGGTFTISNGGTYGSLFGMPILNPPQSAILGMHAVQNRPVVRGDQIVARPMMYLALTY 533
Query: 363 DHRLIDGREAVLFLRKIKEGVEDPATIV 446
DHRLIDGREAV FL+ IKE VE+P+ ++
Sbjct: 534 DHRLIDGREAVTFLKTIKEIVEEPSKLL 561
>UniRef50_Q553V8 Cluster: Dihydrolipoamide S-succinyltransferase;
n=2; Dictyostelium discoideum|Rep: Dihydrolipoamide
S-succinyltransferase - Dictyostelium discoideum AX4
Length = 439
Score = 208 bits (509), Expect = 8e-53
Identities = 97/150 (64%), Positives = 123/150 (82%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEE 185
+EEN+I+Y + V+I+VAV+ P+GLVVPVIRN +N+++ADIE I L+ AR L IE+
Sbjct: 290 VEENDIVYHNNVNINVAVSAPRGLVVPVIRNCENLSFADIEKEIGRLSGLARNDALAIED 349
Query: 186 MDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYD 365
GGTFTISNGGVFGS+ GTPIINPPQSAILGMH I +RP +NGQVV+RP+MY+ALTYD
Sbjct: 350 SIGGTFTISNGGVFGSMFGTPIINPPQSAILGMHAIKDRPYVVNGQVVVRPIMYLALTYD 409
Query: 366 HRLIDGREAVLFLRKIKEGVEDPATIVAGL 455
HR+IDGREAV FL+KIK+ +E+P I+ L
Sbjct: 410 HRIIDGREAVTFLKKIKDVLENPERILLEL 439
>UniRef50_P0AFG7 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=24; Enterobacteriaceae|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Escherichia coli O157:H7
Length = 405
Score = 200 bits (489), Expect = 2e-50
Identities = 93/147 (63%), Positives = 119/147 (80%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEE 185
I+ ++++Y +Y D+S+AV+TP+GLV PV+R+V + ADIE I LA K R GKLT+E+
Sbjct: 256 IDGDDVVYHNYFDVSMAVSTPRGLVTPVLRDVDTLGMADIEKKIKELAVKGRDGKLTVED 315
Query: 186 MDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYD 365
+ GG FTI+NGGVFGSLM TPIINPPQSAILGMH I +RP+A+NGQV I PMMY+AL+YD
Sbjct: 316 LTGGNFTITNGGVFGSLMSTPIINPPQSAILGMHAIKDRPMAVNGQVEILPMMYLALSYD 375
Query: 366 HRLIDGREAVLFLRKIKEGVEDPATIV 446
HRLIDGRE+V FL IKE +EDP ++
Sbjct: 376 HRLIDGRESVGFLVTIKELLEDPTRLL 402
>UniRef50_Q63TQ8 Cluster: Dihydrolipoamide succinyltransferase
component of 2-oxoglutarate dehydrogenase complex; n=42;
Proteobacteria|Rep: Dihydrolipoamide succinyltransferase
component of 2-oxoglutarate dehydrogenase complex -
Burkholderia pseudomallei (Pseudomonas pseudomallei)
Length = 425
Score = 200 bits (488), Expect = 3e-50
Identities = 90/150 (60%), Positives = 119/150 (79%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEE 185
I+ N+I+Y Y DI +AV +P+GLVVP++RN ++ A+IE IA +KA+ GKL+IEE
Sbjct: 276 IDGNDIVYHGYFDIGIAVGSPRGLVVPILRNADQLSLAEIEKKIAEFGQKAKDGKLSIEE 335
Query: 186 MDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYD 365
M GGTF+ISNGGVFGS++ TPIINPPQSAILG+H ERP+ NGQ+VIRP+ Y+AL+YD
Sbjct: 336 MTGGTFSISNGGVFGSMLSTPIINPPQSAILGVHATKERPVVENGQIVIRPINYLALSYD 395
Query: 366 HRLIDGREAVLFLRKIKEGVEDPATIVAGL 455
HR+IDGREAVL L +K+ +EDPA ++ L
Sbjct: 396 HRIIDGREAVLSLVAMKDALEDPARLLLDL 425
>UniRef50_Q82SG4 Cluster: SucB; dihydrolipoamide succinyltransferase
(Component of 2- oxoglutarate dehydrogenase complex)
protein; n=4; Bacteria|Rep: SucB; dihydrolipoamide
succinyltransferase (Component of 2- oxoglutarate
dehydrogenase complex) protein - Nitrosomonas europaea
Length = 425
Score = 200 bits (487), Expect = 4e-50
Identities = 90/145 (62%), Positives = 118/145 (81%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEE 185
++ N+IIY DY DI +AVA+P+GLVVP+IR+ +T+A IE IA LA +A+ GKLT+EE
Sbjct: 276 VDGNDIIYHDYYDIGIAVASPRGLVVPIIRDADKLTFAGIEKQIADLARRAQEGKLTLEE 335
Query: 186 MDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYD 365
+ GGTF+I+NGGVFGS++ TPIINPPQSAILG+H +RP+ NGQ+VIRP+ Y+AL+YD
Sbjct: 336 LTGGTFSITNGGVFGSMLSTPIINPPQSAILGIHATKQRPVVENGQIVIRPINYLALSYD 395
Query: 366 HRLIDGREAVLFLRKIKEGVEDPAT 440
HR+IDGREAVL L IKE +E P +
Sbjct: 396 HRIIDGREAVLSLVAIKEALEYPVS 420
>UniRef50_A5EW59 Cluster: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase; n=1;
Dichelobacter nodosus VCS1703A|Rep: 2-oxoglutarate
dehydrogenase, E2 component, dihydrolipoamide
succinyltransferase - Dichelobacter nodosus (strain
VCS1703A)
Length = 341
Score = 198 bits (484), Expect = 9e-50
Identities = 88/151 (58%), Positives = 121/151 (80%)
Frame = +3
Query: 3 VIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIE 182
+I+ ++++YR Y +I +AVA+P+GLVVP++RN + +++ADIE I AEKA G L++E
Sbjct: 191 MIDGDDVVYRRYCNIGIAVASPRGLVVPILRNAETLSFADIERQIKIFAEKAADGSLSLE 250
Query: 183 EMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTY 362
E+ GTFTI+NGG FGS++ TPI+NPPQSAILGMH I +RP+ NG +VIRP+MY+AL+Y
Sbjct: 251 EISDGTFTITNGGTFGSMLSTPILNPPQSAILGMHAIVDRPMVENGAIVIRPVMYVALSY 310
Query: 363 DHRLIDGREAVLFLRKIKEGVEDPATIVAGL 455
DHRLIDGREAVLFL+ IK +E PA ++ L
Sbjct: 311 DHRLIDGREAVLFLKTIKNMLEAPARLLLDL 341
>UniRef50_Q0E0X4 Cluster: Os02g0514700 protein; n=2; Oryza
sativa|Rep: Os02g0514700 protein - Oryza sativa subsp.
japonica (Rice)
Length = 497
Score = 197 bits (481), Expect = 2e-49
Identities = 95/148 (64%), Positives = 117/148 (79%)
Frame = +3
Query: 3 VIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIE 182
VI+ ++IIYR+Y+DISVAV T KGLVV VI ++ M +ADIE I LA+KA G +I
Sbjct: 347 VIDGDDIIYREYIDISVAVGTSKGLVVLVIHDIDAMNFADIEKGINNLAKKATEGAQSIN 406
Query: 183 EMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTY 362
M GGTFTISNGGV+GSL+ TPIIN PQS+ILGMH I +R + +NG V+ RPMMY+AL Y
Sbjct: 407 NMAGGTFTISNGGVYGSLISTPIINSPQSSILGMHSIVQRLVVVNGSVLARPMMYLALMY 466
Query: 363 DHRLIDGREAVLFLRKIKEGVEDPATIV 446
DHRLIDGREAVLFLR+IK+ VEDP ++
Sbjct: 467 DHRLIDGREAVLFLRRIKDVVEDPRRLL 494
>UniRef50_Q7RIU5 Cluster: 2-oxoglutarate dehydrogenase, E2 component,
dihydrolipoamide succinyltransferase, putative; n=12;
cellular organisms|Rep: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase, putative
- Plasmodium yoelii yoelii
Length = 1632
Score = 197 bits (480), Expect = 3e-49
Identities = 88/143 (61%), Positives = 116/143 (81%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEE 185
I+ +EI+Y++Y+DISVAVATP GL VPVIR+ QN +EL ++ +A KA+ KL++++
Sbjct: 1483 IDNDEIVYKNYIDISVAVATPNGLTVPVIRDCQNKNLPQLELALSDIAAKAKNNKLSLDD 1542
Query: 186 MDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYD 365
GGTFTISNGGVFGS++ TPIIN PQSAILGMH I RP+ +N ++VIRP+MY+ALTYD
Sbjct: 1543 FTGGTFTISNGGVFGSMLSTPIINMPQSAILGMHTIKNRPVVVNNEIVIRPVMYLALTYD 1602
Query: 366 HRLIDGREAVLFLRKIKEGVEDP 434
HRL+DGREAV FL IK+ +E+P
Sbjct: 1603 HRLLDGREAVQFLCAIKDYIENP 1625
>UniRef50_Q2UQN3 Cluster: Dihydrolipoamide succinyltransferase; n=3;
Trichocomaceae|Rep: Dihydrolipoamide succinyltransferase
- Aspergillus oryzae
Length = 448
Score = 197 bits (480), Expect = 3e-49
Identities = 88/145 (60%), Positives = 121/145 (83%)
Frame = +3
Query: 12 ENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMD 191
++ I++ DY+D+SVAVATPKGLV PV+RN++ +IE IA L +KAR GKLT++++
Sbjct: 302 DDTIVFHDYIDLSVAVATPKGLVTPVLRNMERQGIVEIEQGIAELGKKARDGKLTMDDLV 361
Query: 192 GGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHR 371
GG+FTISN G++GSL GTPIIN PQ+A+LG++GI +RP+A++GQV IRPMMY ALTYDHR
Sbjct: 362 GGSFTISNSGIWGSLFGTPIINIPQTAVLGIYGIQQRPVAIDGQVEIRPMMYTALTYDHR 421
Query: 372 LIDGREAVLFLRKIKEGVEDPATIV 446
L+DGREAV FL +K+ +EDPA+++
Sbjct: 422 LVDGREAVTFLTLVKKYLEDPASML 446
>UniRef50_Q39RZ0 Cluster: Dihydrolipoamide succinyltransferase; n=3;
Geobacter|Rep: Dihydrolipoamide succinyltransferase -
Geobacter metallireducens (strain GS-15 / ATCC 53774 /
DSM 7210)
Length = 418
Score = 196 bits (479), Expect = 4e-49
Identities = 84/143 (58%), Positives = 115/143 (80%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEE 185
IE ++I++ Y I +A+ KGLVVPV+R+ +++A+IE TIAG AEK + +L + +
Sbjct: 269 IEGDDIVFHHYYHIGIAIGAEKGLVVPVLRDADRLSFAEIETTIAGFAEKTKANRLELSD 328
Query: 186 MDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYD 365
+ GGTFTISNGGV+GSL+ TPI+NPPQS +LGMH + ERP+ +GQ+VIRPMMY+AL+YD
Sbjct: 329 LQGGTFTISNGGVYGSLLSTPILNPPQSGVLGMHAVQERPVVRDGQIVIRPMMYLALSYD 388
Query: 366 HRLIDGREAVLFLRKIKEGVEDP 434
HR+IDGREAV FL+K+KE VE+P
Sbjct: 389 HRIIDGREAVGFLKKVKEYVEEP 411
>UniRef50_A5CEI9 Cluster: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase; n=1;
Orientia tsutsugamushi Boryong|Rep: 2-oxoglutarate
dehydrogenase, E2 component, dihydrolipoamide
succinyltransferase - Orientia tsutsugamushi (strain
Boryong) (Rickettsia tsutsugamushi)
Length = 425
Score = 196 bits (477), Expect = 6e-49
Identities = 85/150 (56%), Positives = 119/150 (79%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEE 185
++ +I+Y +Y DI VAV+T GLVVP+IRN +++++A+IE+ I+ L +KAR G L+I E
Sbjct: 276 VDGYDILYHNYCDIGVAVSTNSGLVVPIIRNAEHLSFAEIEMEISQLGKKAREGNLSINE 335
Query: 186 MDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYD 365
+ GGTF+I+NGGVFGSL+ TPIINPPQSAI+GMH I +RP+ +NG + IRPMMYI L+YD
Sbjct: 336 LSGGTFSITNGGVFGSLLSTPIINPPQSAIMGMHKIQDRPVVINGTIQIRPMMYIVLSYD 395
Query: 366 HRLIDGREAVLFLRKIKEGVEDPATIVAGL 455
HR+IDG+EAV FL K+K +E P ++ +
Sbjct: 396 HRIIDGKEAVTFLTKVKSYIESPERLLLNI 425
>UniRef50_A0M5Y1 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=7; Flavobacteria|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Gramella forsetii (strain KT0803)
Length = 438
Score = 195 bits (476), Expect = 8e-49
Identities = 89/148 (60%), Positives = 119/148 (80%)
Frame = +3
Query: 3 VIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIE 182
+I+ + I DY DIS+AV+ PKGL VPVIRN +N+++ +E + LA KAR GK+T++
Sbjct: 280 MIDGDYQISYDYKDISIAVSGPKGLTVPVIRNAENLSFRGVESEVKRLAIKARDGKITVD 339
Query: 183 EMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTY 362
EM GGTFTI+NGGVFGS++ TPIINPPQSAILGMH I ERP+A++G V IRP+MY+AL+Y
Sbjct: 340 EMTGGTFTITNGGVFGSMLSTPIINPPQSAILGMHNIVERPVAIDGHVEIRPIMYVALSY 399
Query: 363 DHRLIDGREAVLFLRKIKEGVEDPATIV 446
DHR+IDG+E+V FL IKE +E+P ++
Sbjct: 400 DHRIIDGKESVGFLVAIKEALENPEELL 427
>UniRef50_Q8DFQ0 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex, dihydrolipoamide acyltransferase component;
n=17; Bacteria|Rep: Pyruvate/2-oxoglutarate
dehydrogenase complex, dihydrolipoamide acyltransferase
component - Vibrio vulnificus
Length = 402
Score = 194 bits (474), Expect = 1e-48
Identities = 90/147 (61%), Positives = 120/147 (81%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEE 185
I+ ++I+Y +Y DIS+AV+TP+GLV PV+++ + +AD+E I LA K R GKLT++E
Sbjct: 253 IDGDDIVYHNYFDISMAVSTPRGLVTPVLKDCDTLGFADVEKGIKELAIKGRDGKLTVDE 312
Query: 186 MDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYD 365
+ GG FTI+NGGVFGSLM TPIINPPQSAILGMH I +RP+A++G+V I PMMY+AL+YD
Sbjct: 313 LIGGNFTITNGGVFGSLMSTPIINPPQSAILGMHKIQDRPMAVDGKVEILPMMYLALSYD 372
Query: 366 HRLIDGREAVLFLRKIKEGVEDPATIV 446
HRLIDGRE+V FL +KE +EDPA ++
Sbjct: 373 HRLIDGRESVGFLVTVKELLEDPARLL 399
>UniRef50_Q5P9T5 Cluster: Dihydrolipoamide acetyltransferase
component; n=6; Anaplasmataceae|Rep: Dihydrolipoamide
acetyltransferase component - Anaplasma marginale
(strain St. Maries)
Length = 437
Score = 193 bits (470), Expect = 4e-48
Identities = 87/143 (60%), Positives = 113/143 (79%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEE 185
I +EIIYRDY +I VAV T KGLVVPVIR + M++A +E + L++KAR G LT+ +
Sbjct: 288 ISGDEIIYRDYCNIGVAVGTDKGLVVPVIRGAETMSFAALEQELVMLSKKARGGTLTVAD 347
Query: 186 MDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYD 365
M G TFTI+NGGV+GSL+ TPIINPPQS ILGMH I ERP+ +NG + IRPMMY+AL+YD
Sbjct: 348 MSGATFTITNGGVYGSLLSTPIINPPQSGILGMHAIQERPVVVNGNIEIRPMMYLALSYD 407
Query: 366 HRLIDGREAVLFLRKIKEGVEDP 434
HR++DG+ AV FL ++K+ +EDP
Sbjct: 408 HRIVDGQGAVTFLVRVKQYIEDP 430
>UniRef50_Q5FS04 Cluster: Dihydrolipoamide succinyl transferase (E2)
of 2-oxoglutarate dehydrogenase; n=6; cellular
organisms|Rep: Dihydrolipoamide succinyl transferase
(E2) of 2-oxoglutarate dehydrogenase - Gluconobacter
oxydans (Gluconobacter suboxydans)
Length = 369
Score = 193 bits (470), Expect = 4e-48
Identities = 85/150 (56%), Positives = 119/150 (79%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEE 185
IE +EI+YRD+V++ +AV T +GLVVPV+ + M++A++E IA ++ARTG L +EE
Sbjct: 220 IEGDEIVYRDFVNLGIAVGTERGLVVPVLHDADQMSFAELERRIADYGKRARTGGLKLEE 279
Query: 186 MDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYD 365
+ GTF+I+NGG+FGSL+ TPI+N PQS ILGMH I +RP+ +GQ+VIRPMMY+AL+YD
Sbjct: 280 LSHGTFSITNGGIFGSLLSTPILNTPQSGILGMHAIQDRPVVRDGQIVIRPMMYVALSYD 339
Query: 366 HRLIDGREAVLFLRKIKEGVEDPATIVAGL 455
HR++DGREAV FL +IK+ VEDP ++ L
Sbjct: 340 HRIVDGREAVSFLVRIKQLVEDPRRLLLDL 369
>UniRef50_Q4Q822 Cluster: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase,
putative; n=5; Trypanosomatidae|Rep: 2-oxoglutarate
dehydrogenase, E2 component, dihydrolipoamide
succinyltransferase, putative - Leishmania major
Length = 389
Score = 193 bits (470), Expect = 4e-48
Identities = 93/148 (62%), Positives = 115/148 (77%)
Frame = +3
Query: 12 ENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMD 191
++ I Y ++VDI++AVATP+GLVVPVIR+VQNM A+IE IA A +AR KLT+ EM
Sbjct: 241 KDTIDYHEFVDIAIAVATPRGLVVPVIRDVQNMNLANIETAIADYAARARINKLTMAEMT 300
Query: 192 GGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHR 371
GGTFTISNGGVFGS MGTPIINPP SAILGMH I ++P + ++ IR +M +ALTYDHR
Sbjct: 301 GGTFTISNGGVFGSWMGTPIINPPHSAILGMHAIKKKPWVVGNEIKIRDIMAVALTYDHR 360
Query: 372 LIDGREAVLFLRKIKEGVEDPATIVAGL 455
LIDG +AV FL K+K +EDPA +V L
Sbjct: 361 LIDGSDAVTFLVKVKNLIEDPARMVLDL 388
>UniRef50_UPI000023F136 Cluster: hypothetical protein FG10947.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG10947.1 - Gibberella zeae PH-1
Length = 442
Score = 192 bits (469), Expect = 6e-48
Identities = 84/146 (57%), Positives = 119/146 (81%), Gaps = 1/146 (0%)
Frame = +3
Query: 12 ENEII-YRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEM 188
E EII Y DYVD+S+AV+ PKGLV PV+RN ++++ ++E +A A+KAR GKLT+E+M
Sbjct: 295 EKEIITYHDYVDVSIAVSAPKGLVTPVLRNTESLSIVELERAVAAAAKKARDGKLTMEDM 354
Query: 189 DGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDH 368
+GG+F+ISN G+FGS+ GTP+IN PQ+A+ M+GI + +A+NG+ VIRPMMYI+LTYDH
Sbjct: 355 EGGSFSISNPGIFGSMFGTPVINYPQAAVFNMNGIRQEVVAINGEAVIRPMMYISLTYDH 414
Query: 369 RLIDGREAVLFLRKIKEGVEDPATIV 446
RLIDGREA +FL +K+ +EDP+ ++
Sbjct: 415 RLIDGREASMFLNTVKKYIEDPSRML 440
>UniRef50_Q98ED1 Cluster: Dihydrolipoamide succinyl transferase;
n=8; Bacteria|Rep: Dihydrolipoamide succinyl transferase
- Rhizobium loti (Mesorhizobium loti)
Length = 424
Score = 192 bits (469), Expect = 6e-48
Identities = 87/150 (58%), Positives = 115/150 (76%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEE 185
I+ +IIY+++ + VAV T KGLVVPV+R+ M+ A+IE I L AR GKL++ +
Sbjct: 275 IDGTDIIYKNFAHVGVAVGTEKGLVVPVVRDADQMSIAEIEKEIGRLGIAARDGKLSVAD 334
Query: 186 MDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYD 365
M GGTFTISNGGV+GSLM TPI+N PQS ILGMH I +RP+ + GQ+VIRPMMY+AL+YD
Sbjct: 335 MQGGTFTISNGGVYGSLMSTPILNAPQSGILGMHKIQDRPVVVGGQIVIRPMMYLALSYD 394
Query: 366 HRLIDGREAVLFLRKIKEGVEDPATIVAGL 455
HR++DG+EAV FL ++KE +EDP +V L
Sbjct: 395 HRIVDGKEAVTFLVRVKESLEDPERLVLDL 424
>UniRef50_A0LAA3 Cluster: 2-oxoglutarate dehydrogenase, E2 subunit,
dihydrolipoamide succinyltransferase; n=11;
Proteobacteria|Rep: 2-oxoglutarate dehydrogenase, E2
subunit, dihydrolipoamide succinyltransferase -
Magnetococcus sp. (strain MC-1)
Length = 446
Score = 191 bits (466), Expect = 1e-47
Identities = 87/148 (58%), Positives = 120/148 (81%), Gaps = 1/148 (0%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEE 185
I+ NEI++++Y DI VAV +P+GLVVPV+R M+ A IE TIAG+ ++AR G+L++EE
Sbjct: 296 IQGNEIVFKNYYDIGVAVGSPQGLVVPVLRGADAMSLAGIESTIAGMGKRARDGQLSMEE 355
Query: 186 MDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIAL-NGQVVIRPMMYIALTY 362
M GGTFTI+NGG+FGSL+ TPI+N PQSAILGMH I +R + + +G + RPMMY+AL+Y
Sbjct: 356 MSGGTFTITNGGIFGSLLSTPILNTPQSAILGMHKIQQRAMVMPDGSIQARPMMYLALSY 415
Query: 363 DHRLIDGREAVLFLRKIKEGVEDPATIV 446
DHR++DG+EAV FL +IK+ +EDPA I+
Sbjct: 416 DHRIVDGKEAVSFLVRIKDCIEDPARIL 443
>UniRef50_Q4UGK1 Cluster: Dihydrolipoamide succinyltransferase
component of 2-oxoglutarate dehydrogenase complex,
mitochondrial, putative; n=2; Theileria|Rep:
Dihydrolipoamide succinyltransferase component of
2-oxoglutarate dehydrogenase complex, mitochondrial,
putative - Theileria annulata
Length = 457
Score = 191 bits (466), Expect = 1e-47
Identities = 87/147 (59%), Positives = 119/147 (80%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEE 185
I+ E++ ++YVDISVAVATP GL+VPVIRN + + ++EL++ +A+KAR G +TIE+
Sbjct: 309 IDGKEMVTKNYVDISVAVATPTGLLVPVIRNCEFKNWEELELSLLEMAKKARDGSITIED 368
Query: 186 MDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYD 365
M GGTFTISNGGV+GSL+ TPIINPPQS+ILGMH I +R + + +VIRP+M +ALTYD
Sbjct: 369 MTGGTFTISNGGVYGSLLSTPIINPPQSSILGMHAITKRAVVRDDNIVIRPVMNVALTYD 428
Query: 366 HRLIDGREAVLFLRKIKEGVEDPATIV 446
HRLIDGR+AV FL IK+ +E+P+ ++
Sbjct: 429 HRLIDGRDAVTFLNTIKKFIENPSLLL 455
>UniRef50_Q7ULX6 Cluster: Dihydrolipoamide succinyltransferase
component of 2-oxoglutarate dehydrogenase complex; n=10;
Bacteria|Rep: Dihydrolipoamide succinyltransferase
component of 2-oxoglutarate dehydrogenase complex -
Rhodopirellula baltica
Length = 435
Score = 191 bits (465), Expect = 2e-47
Identities = 87/146 (59%), Positives = 115/146 (78%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEE 185
I + ++YR+Y DI +A+ KGLVVPV+RNV+ M++A++E +IA A A +L +
Sbjct: 286 IRGDSMVYRNYQDIGIAIGGGKGLVVPVLRNVERMSFAEVEGSIAEYARLAGENRLQPSD 345
Query: 186 MDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYD 365
+ GGTFTISNGG++GSL+ TPI+NPPQS ILG+H I ERP+A +GQVVIRPMMY+ALTYD
Sbjct: 346 LMGGTFTISNGGIYGSLLSTPIVNPPQSGILGLHSIQERPVAEDGQVVIRPMMYVALTYD 405
Query: 366 HRLIDGREAVLFLRKIKEGVEDPATI 443
HR++DGREAV FL IKE +EDPA +
Sbjct: 406 HRIVDGREAVGFLVAIKETIEDPARL 431
>UniRef50_A6DL93 Cluster: Dihydrolipoamide acetyltransferase; n=1;
Lentisphaera araneosa HTCC2155|Rep: Dihydrolipoamide
acetyltransferase - Lentisphaera araneosa HTCC2155
Length = 415
Score = 190 bits (464), Expect = 2e-47
Identities = 89/150 (59%), Positives = 115/150 (76%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEE 185
++ N IIY D+VD+ +AV+TPKGLVVPVIR+ + ++ IE I LA K R LT EE
Sbjct: 266 VDGNSIIYHDFVDMGIAVSTPKGLVVPVIRDCDQLNFSGIERKIRELALKGRDMDLTPEE 325
Query: 186 MDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYD 365
M GGTFTI+NGG FGS++ TPI+N PQSAILGMH I ERP+A+NGQV +RP+MY+A++YD
Sbjct: 326 MTGGTFTITNGGTFGSMLSTPILNRPQSAILGMHNIVERPVAVNGQVEVRPIMYLAVSYD 385
Query: 366 HRLIDGREAVLFLRKIKEGVEDPATIVAGL 455
HR+IDG +AV FL KIK +EDP ++ L
Sbjct: 386 HRIIDGSDAVRFLVKIKTLLEDPTRMLLEL 415
>UniRef50_Q1QQR6 Cluster: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase; n=2;
Proteobacteria|Rep: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase -
Nitrobacter hamburgensis (strain X14 / DSM 10229)
Length = 413
Score = 190 bits (462), Expect = 4e-47
Identities = 86/150 (57%), Positives = 117/150 (78%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEE 185
I+ ++IY++Y I +AV T KGLVVPV+R+ + A+IE +IA +AR G+L I+E
Sbjct: 264 IDGTDLIYKNYYHIGIAVGTDKGLVVPVVRDCDRKSIAEIEKSIADYGRRARDGQLKIDE 323
Query: 186 MDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYD 365
M GGTFTI+NGG++GSLM TPI+N PQ+ ILGMH I ERP+A+ G+V IRPMMY+AL+YD
Sbjct: 324 MQGGTFTITNGGIYGSLMSTPILNAPQAGILGMHKIQERPMAIAGKVEIRPMMYLALSYD 383
Query: 366 HRLIDGREAVLFLRKIKEGVEDPATIVAGL 455
HR+IDG++AV FL ++KE +EDPA +V L
Sbjct: 384 HRVIDGKDAVTFLVRVKESLEDPARLVLDL 413
>UniRef50_A0H458 Cluster: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase; n=2;
Chloroflexus|Rep: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase -
Chloroflexus aggregans DSM 9485
Length = 469
Score = 189 bits (461), Expect = 5e-47
Identities = 87/147 (59%), Positives = 112/147 (76%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEE 185
I+ E++ + Y DI +AV +GLVVPV+R+ T+A IE IA LA+KAR G L++ E
Sbjct: 320 IQGEEVVIKYYYDIGIAVGVDEGLVVPVVRDADRKTFAQIEREIAQLAKKAREGTLSLAE 379
Query: 186 MDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYD 365
+ GGTFTI+NGGV+GSLM TPI+N PQ ILGMH I ERP+ +NGQ+VIRPMMY+AL+YD
Sbjct: 380 LQGGTFTITNGGVYGSLMSTPILNAPQVGILGMHKIEERPVVVNGQIVIRPMMYVALSYD 439
Query: 366 HRLIDGREAVLFLRKIKEGVEDPATIV 446
HRLIDG AV FL K+KE +EDP ++
Sbjct: 440 HRLIDGSTAVRFLVKVKELIEDPEALL 466
>UniRef50_Q3SEX1 Cluster: Dihydrolipoamide succinyltransferase; n=1;
Thiobacillus denitrificans ATCC 25259|Rep:
Dihydrolipoamide succinyltransferase - Thiobacillus
denitrificans (strain ATCC 25259)
Length = 379
Score = 189 bits (460), Expect = 7e-47
Identities = 86/143 (60%), Positives = 113/143 (79%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEE 185
I+ N+I++ DI +A+++P+GLVVP++R Q ++ +IE IA A +AR KL +EE
Sbjct: 228 IDGNDIVWHGDADIGIAISSPRGLVVPILRRAQQLSSDEIERAIADFARRARDSKLALEE 287
Query: 186 MDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYD 365
+ GGTF+I+NGGVFGSL+ TPI+NPPQSAILGMH I ERP+A +GQVVIRPMMY+ALTYD
Sbjct: 288 LAGGTFSITNGGVFGSLLSTPILNPPQSAILGMHTIQERPVAEHGQVVIRPMMYLALTYD 347
Query: 366 HRLIDGREAVLFLRKIKEGVEDP 434
HRLIDGR+AV FL +K +E P
Sbjct: 348 HRLIDGRDAVQFLVAVKAALEAP 370
>UniRef50_Q3A0D1 Cluster: 2-oxoglutarate dehydrogenase, E2
component/dihydrolipoamide succinyltransferase; n=2;
Desulfuromonadales|Rep: 2-oxoglutarate dehydrogenase, E2
component/dihydrolipoamide succinyltransferase -
Pelobacter carbinolicus (strain DSM 2380 / Gra Bd 1)
Length = 396
Score = 189 bits (460), Expect = 7e-47
Identities = 84/143 (58%), Positives = 113/143 (79%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEE 185
+EE I+Y+ + DI +AVAT +GLV PV+ N + +ADIE IA LAEKAR +L + +
Sbjct: 248 LEEEAIVYQHFYDIGIAVATDQGLVAPVLLNADRLNFADIEKQIAELAEKARKHRLALAD 307
Query: 186 MDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYD 365
+ GGTF+ISNGGV+GSL+ TP++NPPQSAILGMH I +RP+ + Q+V RPMMY+AL+YD
Sbjct: 308 LQGGTFSISNGGVYGSLLSTPLLNPPQSAILGMHSIQQRPVVRDDQIVARPMMYLALSYD 367
Query: 366 HRLIDGREAVLFLRKIKEGVEDP 434
HRLIDGR+AV FL+++ E VE+P
Sbjct: 368 HRLIDGRDAVNFLKRVVERVEEP 390
>UniRef50_Q89AJ6 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=15; Proteobacteria|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Buchnera aphidicola subsp. Baizongia pistaciae
Length = 410
Score = 189 bits (460), Expect = 7e-47
Identities = 85/150 (56%), Positives = 117/150 (78%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEE 185
I+ +EIIY +Y DIS+A++TP+GLV PV++N M+ A+IE+ I +EK + KLTI++
Sbjct: 261 IDNDEIIYYNYFDISIAISTPRGLVTPVLKNADLMSMAEIEIKIKDFSEKGKNSKLTIDD 320
Query: 186 MDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYD 365
+ GG FTI+NGGVFGSL TP+INPPQSAILGMH I +RP+ ++ + + PMMY+AL+YD
Sbjct: 321 LIGGNFTITNGGVFGSLFSTPLINPPQSAILGMHAIHKRPVIVDENIEVHPMMYLALSYD 380
Query: 366 HRLIDGREAVLFLRKIKEGVEDPATIVAGL 455
HRLIDG+E+V FL KIKE +ED + IV +
Sbjct: 381 HRLIDGKESVGFLLKIKEFLEDFSRIVLNI 410
>UniRef50_Q4UKI7 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=135; root|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Rickettsia felis (Rickettsia azadi)
Length = 401
Score = 188 bits (459), Expect = 9e-47
Identities = 84/150 (56%), Positives = 118/150 (78%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEE 185
I+ ++++Y++Y DI VAV T +GLVVPV+R+ M +A++E I LA+KAR GKL++ +
Sbjct: 252 IDGDDLVYKNYYDIGVAVGTEQGLVVPVVRDADKMGFAEVEKAIGTLAKKAREGKLSMAD 311
Query: 186 MDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYD 365
+ GGTF+ISNGGV+GSL+ TPIINPPQS ILG+H ER + ++G++ IRPMMYIAL+YD
Sbjct: 312 LSGGTFSISNGGVYGSLLSTPIINPPQSGILGLHKTEERAVVIDGKIEIRPMMYIALSYD 371
Query: 366 HRLIDGREAVLFLRKIKEGVEDPATIVAGL 455
HR+IDG+E V FL KIKE +E+P ++ L
Sbjct: 372 HRIIDGKEGVSFLVKIKELIENPEKLLLNL 401
>UniRef50_Q6FYD4 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=79; Bacteria|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Bartonella quintana (Rochalimaea quintana)
Length = 410
Score = 188 bits (458), Expect = 1e-46
Identities = 84/150 (56%), Positives = 114/150 (76%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEE 185
I+ +I+Y++YV+ +AV T KGLVVPV+R+ M+ A+IE I+ L AR GKL + +
Sbjct: 261 IDGTDIVYKNYVNAGIAVGTDKGLVVPVVRDADQMSLAEIEKEISRLGRLARDGKLAVSD 320
Query: 186 MDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYD 365
M GGTFTI+NGGV+GSLM TPI+N PQS ILGMH I ER + + GQ++I PMMY+AL+YD
Sbjct: 321 MQGGTFTITNGGVYGSLMSTPILNAPQSGILGMHAIKERAMVVGGQIIICPMMYLALSYD 380
Query: 366 HRLIDGREAVLFLRKIKEGVEDPATIVAGL 455
HR++DG+EAV FL ++KE +EDP +V L
Sbjct: 381 HRIVDGQEAVTFLVRVKESLEDPERLVLDL 410
>UniRef50_A0LP66 Cluster: 2-oxoglutarate dehydrogenase, E2 subunit,
dihydrolipoamide succinyltransferase; n=1;
Syntrophobacter fumaroxidans MPOB|Rep: 2-oxoglutarate
dehydrogenase, E2 subunit, dihydrolipoamide
succinyltransferase - Syntrophobacter fumaroxidans
(strain DSM 10017 / MPOB)
Length = 444
Score = 188 bits (457), Expect = 2e-46
Identities = 82/147 (55%), Positives = 115/147 (78%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEE 185
IE +EI+Y +Y+ I VAV +GLVVPVIR+V + +AD+E I K R +L + +
Sbjct: 295 IEGHEIVYHNYIHIGVAVGAERGLVVPVIRDVDKLGFADLEKAILDHVRKIRENRLEMSD 354
Query: 186 MDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYD 365
++GGTFTISNGGV+GSLM TPI+N PQS ILG+H I +RP+ ++G++V+RPMMY+AL+YD
Sbjct: 355 LEGGTFTISNGGVYGSLMSTPILNSPQSGILGLHKIEDRPVVVDGRIVVRPMMYVALSYD 414
Query: 366 HRLIDGREAVLFLRKIKEGVEDPATIV 446
HR++DGREAV FL++IKE +E+P I+
Sbjct: 415 HRIVDGREAVTFLKRIKECIENPERIM 441
>UniRef50_O84058 Cluster: Dihydrolipoamide Succinyltransferase; n=7;
Chlamydiaceae|Rep: Dihydrolipoamide Succinyltransferase
- Chlamydia trachomatis
Length = 365
Score = 187 bits (456), Expect = 2e-46
Identities = 85/147 (57%), Positives = 112/147 (76%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEE 185
IE+NEI+YR Y DIS+A+ T +GLVVPVIRN ++ +IEL +A LA +AR GKL I E
Sbjct: 217 IEDNEIVYRHYYDISIAIGTDRGLVVPVIRNCDQLSSGEIELQLADLASRAREGKLAIHE 276
Query: 186 MDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYD 365
++GG FTI+NGGV+GSL+ TPIINPPQ ILGMH I +RP+ +VI MMY+A++YD
Sbjct: 277 LEGGGFTITNGGVYGSLLSTPIINPPQVGILGMHKIEKRPVVREDAIVIADMMYVAMSYD 336
Query: 366 HRLIDGREAVLFLRKIKEGVEDPATIV 446
HR+IDG+EAV FL +KE +E P ++
Sbjct: 337 HRIIDGKEAVGFLVNVKEQLEQPELLL 363
>UniRef50_A4BP63 Cluster: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase; n=4;
Bacteria|Rep: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase -
Nitrococcus mobilis Nb-231
Length = 443
Score = 186 bits (454), Expect = 4e-46
Identities = 84/147 (57%), Positives = 112/147 (76%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEE 185
I+ +IIY Y DI +AV+T +GL+VPV+R+ + +A+IE IA +AR K+ I+E
Sbjct: 294 IDGKDIIYHGYYDIGIAVSTERGLLVPVLRDADQLGFAEIEQAIADFGRRARESKIHIDE 353
Query: 186 MDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYD 365
+ GGTFTI+NGG+FGSLM TPI+NPPQS ILGMH I +RP+ N V +RPMMY+AL+YD
Sbjct: 354 LTGGTFTITNGGIFGSLMSTPILNPPQSGILGMHRIQDRPVVENAAVTVRPMMYLALSYD 413
Query: 366 HRLIDGREAVLFLRKIKEGVEDPATIV 446
HR+IDGREAV FL IKE +EDP+ ++
Sbjct: 414 HRIIDGREAVQFLVTIKELLEDPSRLL 440
>UniRef50_A7AQM6 Cluster: Dihydrolipoamide succinyltransferase,
putative; n=1; Babesia bovis|Rep: Dihydrolipoamide
succinyltransferase, putative - Babesia bovis
Length = 402
Score = 186 bits (453), Expect = 5e-46
Identities = 86/147 (58%), Positives = 115/147 (78%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEE 185
IE ++I+ + +VDISVAVATP GLVVPVIRN + ++ ++E + A K R G+LT+ +
Sbjct: 254 IEGDDIVTKHFVDISVAVATPTGLVVPVIRNCEGKSWIELEQQLVDAAAKGREGRLTVAD 313
Query: 186 MDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYD 365
M GGTFTISNGGV+GS++ TPIINPPQS+ILGMH I +R + + Q+VIRP+M +AL+YD
Sbjct: 314 MTGGTFTISNGGVYGSVLSTPIINPPQSSILGMHSIIKRCVVRDDQMVIRPIMNLALSYD 373
Query: 366 HRLIDGREAVLFLRKIKEGVEDPATIV 446
HRLIDGREAV FL IKE +E+P ++
Sbjct: 374 HRLIDGREAVQFLIAIKEAIENPKVLL 400
>UniRef50_Q6MC86 Cluster: Probable dihydrolipoamide
S-succinyltransferase, (2-oxogluturate dehydrogenase
complex E2 component), sucB; n=1; Candidatus
Protochlamydia amoebophila UWE25|Rep: Probable
dihydrolipoamide S-succinyltransferase, (2-oxogluturate
dehydrogenase complex E2 component), sucB -
Protochlamydia amoebophila (strain UWE25)
Length = 404
Score = 182 bits (442), Expect = 1e-44
Identities = 80/150 (53%), Positives = 112/150 (74%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEE 185
+++ +I+ R Y DI +AV T +G VPV+R ++A IEL I A+KAR GK+ +++
Sbjct: 255 LDQQDIVERHYYDIGIAVGTERGTFVPVVRQCDQQSFAQIELAIDLFAKKARDGKIAMDD 314
Query: 186 MDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYD 365
+ GG FTI+NGGV+GSL+ TPI+NPPQ AILGMH I +RP+ + Q+VIRPMMY+AL+YD
Sbjct: 315 LQGGGFTITNGGVYGSLLSTPILNPPQCAILGMHKIEKRPVVMEDQIVIRPMMYLALSYD 374
Query: 366 HRLIDGREAVLFLRKIKEGVEDPATIVAGL 455
HRLIDG+E+V FL IK +EDP+ ++ L
Sbjct: 375 HRLIDGKESVAFLVHIKNALEDPSRLLLNL 404
>UniRef50_P57389 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=2; Enterobacteriaceae|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Buchnera aphidicola subsp. Acyrthosiphon pisum
(Acyrthosiphon pisumsymbiotic bacterium)
Length = 420
Score = 179 bits (435), Expect = 8e-44
Identities = 83/142 (58%), Positives = 108/142 (76%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEE 185
I++ +I++ DIS+A++TP+GL+ PVIRN MT A+IE I + K K+ I+E
Sbjct: 271 IDQTDIVFYKNFDISIAISTPRGLITPVIRNADTMTMAEIEKKIKDFSIKGLQNKINIKE 330
Query: 186 MDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYD 365
+ GG FTI+NGGVFGSLM TPIINPPQ+AILGMH I ERP+ +NGQ+ I PMMY+AL+YD
Sbjct: 331 LMGGNFTITNGGVFGSLMSTPIINPPQTAILGMHVIQERPVVVNGQIKILPMMYLALSYD 390
Query: 366 HRLIDGREAVLFLRKIKEGVED 431
HRLIDG+E+V FL IK +ED
Sbjct: 391 HRLIDGKESVGFLINIKNILED 412
>UniRef50_Q057P2 Cluster: 2-oxoglutarate dehydrogenase E2 component;
n=1; Buchnera aphidicola str. Cc (Cinara cedri)|Rep:
2-oxoglutarate dehydrogenase E2 component - Buchnera
aphidicola subsp. Cinara cedri
Length = 398
Score = 176 bits (428), Expect = 5e-43
Identities = 78/142 (54%), Positives = 107/142 (75%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEE 185
IE+ IIY DY DI++A++TP+GL+ P+++N N++ +IE I GKL E+
Sbjct: 249 IEKKNIIYHDYYDINIAISTPRGLITPILKNTDNLSIYEIEKKIKSFVLLGEQGKLKFED 308
Query: 186 MDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYD 365
++ GTFTI+NGGVFGSLM TPIINPPQ AILGMH I +RPI +N ++ I PMMY+AL+YD
Sbjct: 309 LEAGTFTITNGGVFGSLMSTPIINPPQVAILGMHHIKKRPIVVNKKIKILPMMYLALSYD 368
Query: 366 HRLIDGREAVLFLRKIKEGVED 431
H+LIDG++A+ FL IK+ +ED
Sbjct: 369 HQLIDGKQAIQFLNYIKDILED 390
>UniRef50_P16263 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=95; Bacteria|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Bacillus subtilis
Length = 417
Score = 168 bits (409), Expect = 1e-40
Identities = 81/148 (54%), Positives = 110/148 (74%), Gaps = 1/148 (0%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEE 185
I+ +E+I + + DI +AVA +GLVVPV+R+ +T+A IE I LA+KAR KLT+ E
Sbjct: 267 IQGDELIVKKFYDIGIAVAAVEGLVVPVVRDADRLTFAGIEKEIGELAKKARNNKLTLSE 326
Query: 186 MDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQ-VVIRPMMYIALTY 362
++GG+FTI+NGG FGSLM TPI+N PQ ILGMH I RP+A++ + RPMMYIAL+Y
Sbjct: 327 LEGGSFTITNGGTFGSLMSTPILNSPQVGILGMHKIQLRPVAIDEERFENRPMMYIALSY 386
Query: 363 DHRLIDGREAVLFLRKIKEGVEDPATIV 446
DHR++DG+EAV FL IK +EDP ++
Sbjct: 387 DHRIVDGKEAVGFLVTIKNLLEDPEQLL 414
>UniRef50_Q49XM4 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=35; Bacillales|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Staphylococcus saprophyticus subsp. saprophyticus
(strain ATCC 15305 /DSM 20229)
Length = 424
Score = 165 bits (401), Expect = 1e-39
Identities = 79/148 (53%), Positives = 110/148 (74%), Gaps = 1/148 (0%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEE 185
I+ +++I + Y DI VAV+T GL+VP +R+ +A+IE I LA+KAR KL +++
Sbjct: 274 IDGDDMITKQYYDIGVAVSTEDGLLVPFVRDCDKKNFAEIEDEIGNLAKKARDKKLGLDD 333
Query: 186 MDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVV-IRPMMYIALTY 362
M G+FTI+NGG+FGS+M TPIIN Q+AILGMH I RPIA++ + RPMMYIAL+Y
Sbjct: 334 MVNGSFTITNGGIFGSMMSTPIINGSQAAILGMHSIITRPIAIDADTIENRPMMYIALSY 393
Query: 363 DHRLIDGREAVLFLRKIKEGVEDPATIV 446
DHR+IDG+EAV FL+ IKE +E+P ++
Sbjct: 394 DHRIIDGKEAVGFLKTIKELIENPEDLL 421
>UniRef50_Q8R9E5 Cluster: Dihydrolipoamide acyltransferases; n=3;
Bacteria|Rep: Dihydrolipoamide acyltransferases -
Thermoanaerobacter tengcongensis
Length = 219
Score = 137 bits (332), Expect = 2e-31
Identities = 65/147 (44%), Positives = 102/147 (69%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEE 185
IE +EII +++ +AVA GL+VPV++N +N + ++ I L+EKAR KLT +E
Sbjct: 72 IEGDEIIKNPNINLGIAVALEDGLIVPVVKNAENKSLLELSKEIKELSEKARENKLTPDE 131
Query: 186 MDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYD 365
+ GGTFTI+N G++ TPIINPP+SAILG++ I++ P+ + +VIR M ++L++D
Sbjct: 132 ITGGTFTITNLGMYEIDSFTPIINPPESAILGVNKIYKEPVVIEDNIVIRHTMKLSLSFD 191
Query: 366 HRLIDGREAVLFLRKIKEGVEDPATIV 446
HRLIDG A FL +K+ +E+P +++
Sbjct: 192 HRLIDGATAAKFLLDLKKILENPVSML 218
>UniRef50_A6WD54 Cluster: 2-oxoglutarate dehydrogenase E2 component;
n=5; Actinomycetales|Rep: 2-oxoglutarate dehydrogenase
E2 component - Kineococcus radiotolerans SRS30216
Length = 618
Score = 134 bits (323), Expect = 3e-30
Identities = 64/145 (44%), Positives = 97/145 (66%), Gaps = 4/145 (2%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEE 185
I+ I+Y ++S+AV TPKGL+ PVI++ ++ + IA LA + R K+T ++
Sbjct: 464 IDGENIVYHGSENVSMAVDTPKGLITPVIKDAGDLNLGGLARKIADLAARTRASKITPDD 523
Query: 186 MDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIAL--NGQ--VVIRPMMYIA 353
+ GGTFTI+N G G+L TPI+N PQ AILG I +RP+ L +GQ + IR MMY+A
Sbjct: 524 LSGGTFTITNTGSIGALFDTPILNAPQVAILGTGAIVKRPVVLEVDGQETIAIRSMMYLA 583
Query: 354 LTYDHRLIDGREAVLFLRKIKEGVE 428
L+YDH+++DG +A FL+ +K+ +E
Sbjct: 584 LSYDHQIVDGADAARFLQTVKKRIE 608
>UniRef50_Q9YBC6 Cluster: Pyruvate dehydrogenase complex, E2
component; n=1; Aeropyrum pernix|Rep: Pyruvate
dehydrogenase complex, E2 component - Aeropyrum pernix
Length = 412
Score = 133 bits (321), Expect = 5e-30
Identities = 64/147 (43%), Positives = 99/147 (67%)
Frame = +3
Query: 9 EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEM 188
E+ EI+ + V+I AV TP GLVVPV++NV+ I IA L KAR +L++EE+
Sbjct: 260 EKMEIVVKKAVNIGFAVDTPHGLVVPVVKNVEKKGLFAIAREIADLTAKAREMRLSLEEV 319
Query: 189 DGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDH 368
G TFTI+N G GS++G P+I PP AILG+H + ERP+ ++G++ R + +++L++DH
Sbjct: 320 SGATFTITNVGSIGSVIGFPVIYPPNVAILGVHRLVERPVYVDGELKPRKIGFVSLSFDH 379
Query: 369 RLIDGREAVLFLRKIKEGVEDPATIVA 449
R ++G A FL ++K +E+PA + A
Sbjct: 380 RALEGAYATRFLMEVKRLLENPALLFA 406
>UniRef50_A4AGT3 Cluster: Putative dihydrolipoamide acyltransferase
component; n=1; marine actinobacterium PHSC20C1|Rep:
Putative dihydrolipoamide acyltransferase component -
marine actinobacterium PHSC20C1
Length = 480
Score = 132 bits (319), Expect = 9e-30
Identities = 62/146 (42%), Positives = 95/146 (65%)
Frame = +3
Query: 9 EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEM 188
E NEI+ YV++ +AVATP+GL+VP +++ MT A++ I LA AR K T +
Sbjct: 332 EANEIVEFGYVNLGIAVATPRGLMVPNLKDADMMTLAELTEAIGTLARNARASKATPASL 391
Query: 189 DGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDH 368
+GGT +I+N GVFG GTPI+NP ++AIL M + + P NG+V +R +M ++L++DH
Sbjct: 392 NGGTISITNVGVFGIDAGTPILNPGEAAILAMGAVRKMPWEHNGEVALRDVMTLSLSFDH 451
Query: 369 RLIDGREAVLFLRKIKEGVEDPATIV 446
RL+DG + FL + + DP T++
Sbjct: 452 RLVDGEQGARFLTDVGAILNDPGTVL 477
>UniRef50_Q0W153 Cluster: Pyruvate dehydrogenase complex E2,
dihydrolipoamide acetyltransferase; n=1; uncultured
methanogenic archaeon RC-I|Rep: Pyruvate dehydrogenase
complex E2, dihydrolipoamide acetyltransferase -
Uncultured methanogenic archaeon RC-I
Length = 428
Score = 132 bits (319), Expect = 9e-30
Identities = 62/149 (41%), Positives = 94/149 (63%)
Frame = +3
Query: 9 EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEM 188
E+ EI+ + Y +I +A+ TP+GL+V +++ + I I L E A +GK+ +E++
Sbjct: 279 EKGEIVLKKYYNIGLAIDTPRGLMVAPVKDADRKSIVQISREIKELVELAESGKIGVEQL 338
Query: 189 DGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDH 368
G TFTI+N G G L TPIINPP+SAIL M I + P +G V +R +M ++LT DH
Sbjct: 339 RGSTFTIANIGSIGGLFATPIINPPESAILEMQQIRDMPRVCDGNVCVRKVMNLSLTIDH 398
Query: 369 RLIDGREAVLFLRKIKEGVEDPATIVAGL 455
R+IDG E FL ++K +EDPA ++ +
Sbjct: 399 RIIDGAEGQRFLNEVKGYLEDPAALLVNM 427
>UniRef50_Q9KES1 Cluster: Dihydrolipoamide S-acetyltransferase; n=1;
Bacillus halodurans|Rep: Dihydrolipoamide
S-acetyltransferase - Bacillus halodurans
Length = 436
Score = 132 bits (318), Expect = 1e-29
Identities = 65/141 (46%), Positives = 93/141 (65%)
Frame = +3
Query: 12 ENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMD 191
ENEI+Y + V I +AVA GLVVPV+++V A + +A AR +L+ E M
Sbjct: 291 ENEIVYHEDVHIGLAVAVEGGLVVPVVKHVDKKGLAQLTNECKTVAMAARDNRLSQEMMS 350
Query: 192 GGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHR 371
GGTFTISN G++ + TP+IN P+SAILG+ I E+P+ ++GQ+ +RPMM +L++DHR
Sbjct: 351 GGTFTISNLGMYAIDVFTPVINQPESAILGVGRIQEKPVGIDGQIELRPMMTASLSFDHR 410
Query: 372 LIDGREAVLFLRKIKEGVEDP 434
+IDG A FL +K +E P
Sbjct: 411 VIDGAPAAAFLTDVKSMLEQP 431
>UniRef50_Q8RD59 Cluster: Dihydrolipoamide acyltransferases; n=1;
Thermoanaerobacter tengcongensis|Rep: Dihydrolipoamide
acyltransferases - Thermoanaerobacter tengcongensis
Length = 414
Score = 132 bits (318), Expect = 1e-29
Identities = 69/143 (48%), Positives = 93/143 (65%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEE 185
+EE +II R+ ++I +AVA +GL+VPVIR V +I L +KAR GKLT +E
Sbjct: 267 VEEGQIILRNEINIGLAVALDEGLIVPVIREVDKKGLKEIAREEKALIQKAREGKLTPDE 326
Query: 186 MDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYD 365
GG+FTISN G+F + IINPP+ AIL + I E P+ GQ+ I P+M + L+ D
Sbjct: 327 YTGGSFTISNLGMFDVVRFAAIINPPEVAILAVGKIREIPVVEEGQIEIEPIMEMTLSSD 386
Query: 366 HRLIDGREAVLFLRKIKEGVEDP 434
HR+IDG A FLR+IKE +EDP
Sbjct: 387 HRVIDGALAAKFLRRIKEILEDP 409
>UniRef50_Q67ME8 Cluster: Branched-chain alpha-keto acid
dehydrogenase E2; n=2; Bacilli|Rep: Branched-chain
alpha-keto acid dehydrogenase E2 - Symbiobacterium
thermophilum
Length = 459
Score = 130 bits (315), Expect = 3e-29
Identities = 65/146 (44%), Positives = 95/146 (65%), Gaps = 3/146 (2%)
Frame = +3
Query: 15 NEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDG 194
+EI+ R ++ISVAVAT L VPVI++ ++ A + +A LAE+AR G+LT++++ G
Sbjct: 311 DEIVIRQDINISVAVATEDALAVPVIKHADRLSIAGLNEAVADLAERARAGRLTLDDVTG 370
Query: 195 GTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIAL-NGQVVIRPMMYIALTYDHR 371
GTFT++N G FGS + PIIN PQ+AIL I + P+ L N + IR MM I L+ DHR
Sbjct: 371 GTFTVNNTGAFGSFLSAPIINYPQAAILSFEKITKMPVVLENDAIAIRSMMNICLSLDHR 430
Query: 372 LIDGREAVLFLRKIKEGVED--PATI 443
++DG FL+ +K +E P T+
Sbjct: 431 ILDGLVCGRFLQAVKRRLESYGPGTV 456
>UniRef50_Q5KUY3 Cluster: Pyruvate dehydrogenase E2; n=2;
Geobacillus|Rep: Pyruvate dehydrogenase E2 - Geobacillus
kaustophilus
Length = 431
Score = 130 bits (314), Expect = 3e-29
Identities = 63/146 (43%), Positives = 91/146 (62%)
Frame = +3
Query: 9 EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEM 188
E NEI+ + I +A AT GLVVPVIR+ + ++ + IA L+EKA L +EE+
Sbjct: 282 ETNEIVLKKRYHIGIATATKAGLVVPVIRDADQKSIRELAIEIAELSEKAHRQALRLEEL 341
Query: 189 DGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDH 368
G TFTI++ G G TPIIN P+ AI G H I RP+ + ++VIR MM ++LT+DH
Sbjct: 342 QGSTFTITSTGAGGGWFATPIINYPEVAIFGAHAIKRRPVVVGDEIVIRDMMGMSLTFDH 401
Query: 369 RLIDGREAVLFLRKIKEGVEDPATIV 446
R+IDG A F+R + +E+P ++
Sbjct: 402 RVIDGEPAGRFMRTVAHYLENPEVLL 427
>UniRef50_A4A156 Cluster: Pyruvate dehydrogenase, E2 component,
dihydrolipoamideacetyltransferase; n=2;
Planctomycetaceae|Rep: Pyruvate dehydrogenase, E2
component, dihydrolipoamideacetyltransferase -
Blastopirellula marina DSM 3645
Length = 472
Score = 129 bits (312), Expect = 6e-29
Identities = 61/147 (41%), Positives = 95/147 (64%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEE 185
+E N+++Y++YV++ +AV + +GLVVP IRN + +I + LA R G ++++
Sbjct: 323 MENNQVVYKEYVNVGIAVDSERGLVVPNIRNADRLAIPEIARDVQKLAADVRGGTFSMDQ 382
Query: 186 MDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYD 365
+ GGTFTISN G G TPIIN P+ AIL + + P+ +N Q+V R MM ++L+YD
Sbjct: 383 IRGGTFTISNLGAIGGTYSTPIINVPEVAILLVGRSRKLPVVVNDQIVPRMMMPLSLSYD 442
Query: 366 HRLIDGREAVLFLRKIKEGVEDPATIV 446
HRL+DG A FL +IK +E P+ ++
Sbjct: 443 HRLVDGATAARFLNEIKSYLEAPSRLL 469
>UniRef50_Q5UYG4 Cluster: Dihydrolipoamide acetyltransferase
component of pyruvate dehydrogenase complex; n=2;
Halobacteriaceae|Rep: Dihydrolipoamide acetyltransferase
component of pyruvate dehydrogenase complex - Haloarcula
marismortui (Halobacterium marismortui)
Length = 545
Score = 129 bits (311), Expect = 8e-29
Identities = 62/146 (42%), Positives = 92/146 (63%)
Frame = +3
Query: 9 EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEM 188
E EI+YRD +I VA AT GLVVPV+ +V ++ + L +AR + EM
Sbjct: 398 ENEEIVYRDAHNIGVAAATDHGLVVPVVNDVDGKGLVELAGEVNDLVGRARERDIERSEM 457
Query: 189 DGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDH 368
GGTFT++N GV G +PIIN P++AILG+ + ERP+A +G+VV +P + ++L DH
Sbjct: 458 QGGTFTVTNFGVIGGEYASPIINVPETAILGIGALKERPVAEDGEVVAKPTLPLSLAIDH 517
Query: 369 RLIDGREAVLFLRKIKEGVEDPATIV 446
R+IDG +A F+ +KE + DP ++
Sbjct: 518 RVIDGADAARFVNTLKEYLSDPTRLL 543
>UniRef50_Q749T6 Cluster: Pyruvate dehydrogenase complex E2
component, dihydrolipoamide acetyltransferase; n=4;
Geobacter|Rep: Pyruvate dehydrogenase complex E2
component, dihydrolipoamide acetyltransferase -
Geobacter sulfurreducens
Length = 392
Score = 128 bits (309), Expect = 1e-28
Identities = 62/142 (43%), Positives = 90/142 (63%)
Frame = +3
Query: 18 EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGG 197
EII + + +AV TP GL+VPVIRNV + ++ + L KAR +T++EM G
Sbjct: 246 EIILKKHYHFGIAVETPDGLMVPVIRNVDAKSIIELASELQELGRKARERTITLDEMRGS 305
Query: 198 TFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLI 377
TFT++N G FG + TP+IN P AILG I +RP GQ+V+R ++ ++LT+DHR+
Sbjct: 306 TFTLTNFGHFGGVFATPVINWPDVAILGFGRIADRPWVHAGQIVVRTILPLSLTFDHRVT 365
Query: 378 DGREAVLFLRKIKEGVEDPATI 443
DG +A FL K+ +EDPA +
Sbjct: 366 DGADAAQFLSKVVRYLEDPALL 387
>UniRef50_A0M206 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=1; Gramella forsetii KT0803|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex - Gramella forsetii
(strain KT0803)
Length = 507
Score = 127 bits (307), Expect = 2e-28
Identities = 68/150 (45%), Positives = 91/150 (60%), Gaps = 1/150 (0%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEE 185
+E E+I + YV+I +AV T KGL+VPV+RN T +I I LAEKAR KL+ EE
Sbjct: 357 MENEEMILKKYVNIGIAVDTEKGLLVPVVRNADQKTIIEISTEITELAEKARNVKLSAEE 416
Query: 186 MDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVV-IRPMMYIALTY 362
M GG FTISN G G TPI+ PQ AILG+ ++P+ + R ++ ++L+Y
Sbjct: 417 MKGGNFTISNLGGIGGTNFTPIVYHPQVAILGVSRAKKQPVYKDDDTFEARDILPLSLSY 476
Query: 363 DHRLIDGREAVLFLRKIKEGVEDPATIVAG 452
DHR+IDG E V FL I +EDP + G
Sbjct: 477 DHRIIDGAEGVRFLHWISRALEDPYEALLG 506
>UniRef50_Q3CI28 Cluster: Biotin/lipoyl attachment:Catalytic domain
of components of various dehydrogenase complexes:E3
binding; n=2; Thermoanaerobacter ethanolicus|Rep:
Biotin/lipoyl attachment:Catalytic domain of components
of various dehydrogenase complexes:E3 binding -
Thermoanaerobacter ethanolicus ATCC 33223
Length = 382
Score = 127 bits (306), Expect = 3e-28
Identities = 60/147 (40%), Positives = 98/147 (66%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEE 185
IE II +++ +AVA GL+VPV++ + ++ I L+E+AR KLT +E
Sbjct: 235 IEGEYIIKNSSINLGIAVALDNGLIVPVVKEADKKSLLELSKNIKELSERARNNKLTPDE 294
Query: 186 MDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYD 365
+ G TFTI+N G++ TPIINPP+SAILG++ I++ P+ L+ +VIR ++ ++L++D
Sbjct: 295 IIGSTFTITNLGMYEIDSFTPIINPPESAILGVNKIYKEPVVLDDNIVIRHIIKLSLSFD 354
Query: 366 HRLIDGREAVLFLRKIKEGVEDPATIV 446
HRLIDG A FL +K+ +E+P +++
Sbjct: 355 HRLIDGATAAKFLLDLKKTLENPLSLL 381
>UniRef50_A1SJ23 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=18; Actinomycetales|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Nocardioides sp. (strain BAA-499 / JS614)
Length = 597
Score = 126 bits (305), Expect = 4e-28
Identities = 61/145 (42%), Positives = 98/145 (67%), Gaps = 5/145 (3%)
Frame = +3
Query: 9 EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEM 188
E E+ Y D ++++AV T KGL+ PVI++ +++ A + IA +A++ RT K+ +E+
Sbjct: 447 EAGEVTYYDRENLAIAVDTEKGLITPVIKDAGDLSIAGLAKKIADVAQRTRTNKIGPDEL 506
Query: 189 DGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALN----GQ-VVIRPMMYIA 353
GGTFTI+N G G+L TPI+N PQ AILG + +RP+ ++ G+ + +R M+Y+A
Sbjct: 507 SGGTFTITNLGSVGALWDTPIVNKPQVAILGPGAVVKRPVVIDDPNLGETIAVRYMVYLA 566
Query: 354 LTYDHRLIDGREAVLFLRKIKEGVE 428
LTYDH+L+DG +A FL +K+ +E
Sbjct: 567 LTYDHQLVDGADAGRFLTDVKQRLE 591
>UniRef50_Q088Y7 Cluster: Dihydrolipoyllysine-residue
succinyltransferase; n=1; Shewanella frigidimarina NCIMB
400|Rep: Dihydrolipoyllysine-residue succinyltransferase
- Shewanella frigidimarina (strain NCIMB 400)
Length = 252
Score = 126 bits (303), Expect = 7e-28
Identities = 58/140 (41%), Positives = 92/140 (65%)
Frame = +3
Query: 21 IIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGT 200
++ + Y ++ +AV T GL+VPVI+NV +T ++ + LAE+ R GKLT + +GG+
Sbjct: 111 LMLKHYYNLGIAVDTSNGLLVPVIKNVDALTLEELAIASQQLAERTRAGKLTFADTEGGS 170
Query: 201 FTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLID 380
FT+++ G G TPIIN P+ AILG+ + +A NGQ+VIRPM+ ++L+YDHR+ID
Sbjct: 171 FTVTSLGPMGGTSFTPIINMPEVAILGVSREITKVVAQNGQIVIRPMLPLSLSYDHRVID 230
Query: 381 GREAVLFLRKIKEGVEDPAT 440
G A F+ ++K+ + T
Sbjct: 231 GAMATRFMVQLKQNLSQAET 250
>UniRef50_A1SQB9 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=3; Actinomycetales|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Nocardioides sp. (strain BAA-499 / JS614)
Length = 474
Score = 126 bits (303), Expect = 7e-28
Identities = 64/146 (43%), Positives = 94/146 (64%), Gaps = 4/146 (2%)
Frame = +3
Query: 15 NEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDG 194
+E++Y+ YV++ +A ATP+GLVVP +++ ++MT ++ I + AR GK EM G
Sbjct: 325 HEVVYKRYVNLGIAAATPRGLVVPNVKDAESMTLLELAQAINAVTATAREGKTQPAEMSG 384
Query: 195 GTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERP--IALNGQ--VVIRPMMYIALTY 362
GTFTI+N GVFG GTPIINP +SAIL + ++P + +GQ +V R + +AL +
Sbjct: 385 GTFTITNVGVFGVDSGTPIINPGESAILAFGAVRKQPWVVETDGQDTIVPRQICTLALAF 444
Query: 363 DHRLIDGREAVLFLRKIKEGVEDPAT 440
DHR IDG + FL + E + DPAT
Sbjct: 445 DHRHIDGEKGSRFLADVAEIMADPAT 470
>UniRef50_Q3JBP0 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex dihydrolipoamide acyltransferase (E2) component
and related enzymes; n=1; Nitrosococcus oceani ATCC
19707|Rep: Pyruvate/2-oxoglutarate dehydrogenase complex
dihydrolipoamide acyltransferase (E2) component and
related enzymes - Nitrosococcus oceani (strain ATCC
19707 / NCIMB 11848)
Length = 447
Score = 125 bits (302), Expect = 1e-27
Identities = 64/143 (44%), Positives = 90/143 (62%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEE 185
++ E++Y+ Y I VAV GL+VPVIR A + + + LAEKAR+ K+ EE
Sbjct: 298 VDAKELVYKQYCHIGVAVDAEHGLLVPVIREADQKNIAQLAVELTELAEKARSRKIGPEE 357
Query: 186 MDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYD 365
M GG+FTI+N G G TPIIN P+ AILG+ P+ + G+ R ++ ++L+YD
Sbjct: 358 MAGGSFTITNLGGLGGSYFTPIINWPEVAILGLSRAKMAPLYIEGEFQPRLLLPLSLSYD 417
Query: 366 HRLIDGREAVLFLRKIKEGVEDP 434
HR+IDG +AV FLR I E +EDP
Sbjct: 418 HRVIDGADAVRFLRWIVEALEDP 440
>UniRef50_Q1IMV8 Cluster: Dihydrolipoamide acetyltransferase; n=1;
Acidobacteria bacterium Ellin345|Rep: Dihydrolipoamide
acetyltransferase - Acidobacteria bacterium (strain
Ellin345)
Length = 615
Score = 125 bits (302), Expect = 1e-27
Identities = 64/147 (43%), Positives = 91/147 (61%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEE 185
I+ EIIY+ YV I VAV T GL+VPV+RNV I + L+++AR KL EE
Sbjct: 466 IDREEIIYKKYVHIGVAVDTEAGLLVPVLRNVDQKNVYQIAAEMNELSKRARERKLKPEE 525
Query: 186 MDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYD 365
M+GGTFTI+N G G TPI+N P+ AILG+ P+ +N R M+ ++L+YD
Sbjct: 526 MEGGTFTITNLGGIGGTSFTPIVNLPEVAILGLSRGRTEPVWVNDHFEPRTMLPLSLSYD 585
Query: 366 HRLIDGREAVLFLRKIKEGVEDPATIV 446
HR+IDG +A +LR + + +E P ++
Sbjct: 586 HRIIDGADAARYLRWVADALEQPVLLL 612
>UniRef50_P37942 Cluster: Lipoamide acyltransferase component of
branched-chain alpha-keto acid dehydrogenase complex (EC
2.3.1.168) (Dihydrolipoyllysine-residue (2-
methylpropanoyl)transferase); n=37; Bacillales|Rep:
Lipoamide acyltransferase component of branched-chain
alpha-keto acid dehydrogenase complex (EC 2.3.1.168)
(Dihydrolipoyllysine-residue (2-
methylpropanoyl)transferase) - Bacillus subtilis
Length = 424
Score = 125 bits (302), Expect = 1e-27
Identities = 62/139 (44%), Positives = 91/139 (65%), Gaps = 1/139 (0%)
Frame = +3
Query: 15 NEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDG 194
++II + ++IS+AVAT L VPVI+N T I I GLA+K R GKLT ++M G
Sbjct: 277 DKIIQKKDINISIAVATEDSLFVPVIKNADEKTIKGIAKDITGLAKKVRDGKLTADDMQG 336
Query: 195 GTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIAL-NGQVVIRPMMYIALTYDHR 371
GTFT++N G FGS+ IIN PQ+AIL + I +RP+ + NG + +R M+ + L+ DHR
Sbjct: 337 GTFTVNNTGSFGSVQSMGIINYPQAAILQVESIVKRPVVMDNGMIAVRDMVNLCLSLDHR 396
Query: 372 LIDGREAVLFLRKIKEGVE 428
++DG FL ++K+ +E
Sbjct: 397 VLDGLVCGRFLGRVKQILE 415
>UniRef50_Q3VZH8 Cluster: Biotin/lipoyl attachment:Catalytic domain
of components of various dehydrogenase complexes:E3
binding; n=2; Frankia|Rep: Biotin/lipoyl
attachment:Catalytic domain of components of various
dehydrogenase complexes:E3 binding - Frankia sp. EAN1pec
Length = 475
Score = 124 bits (299), Expect = 2e-27
Identities = 58/136 (42%), Positives = 88/136 (64%)
Frame = +3
Query: 39 VDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNG 218
V + A TP+GLVVPV+R+ Q T A + + L AR G+LT E+ GGTFT++N
Sbjct: 337 VHLGFAAQTPRGLVVPVVRDAQGHTTASLAAEVTRLTAAARAGRLTPAELTGGTFTLNNY 396
Query: 219 GVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLIDGREAVL 398
GVFG TPI+N P+ A++G+ I RP A++G++ +R + ++ T+DHR+ DG A
Sbjct: 397 GVFGVDGATPIVNHPEVAMIGIGRILPRPWAVDGELAVRRITQLSFTFDHRVCDGATAGA 456
Query: 399 FLRKIKEGVEDPATIV 446
FLR + + VE+P T++
Sbjct: 457 FLRFVADAVENPTTLL 472
>UniRef50_Q9RYB8 Cluster: 2-oxo acid dehydrogenase, E2 component;
n=2; Deinococcus|Rep: 2-oxo acid dehydrogenase, E2
component - Deinococcus radiodurans
Length = 525
Score = 124 bits (298), Expect = 3e-27
Identities = 58/140 (41%), Positives = 92/140 (65%), Gaps = 1/140 (0%)
Frame = +3
Query: 18 EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGG 197
EI+ + Y ++ +AVAT GL VPVIR+V + D+ + LA +A GKL+ +E+ G
Sbjct: 378 EIVQKSYYNLGMAVATEAGLTVPVIRDVDRKSIFDLARDVVDLAGRANAGKLSPDELTGS 437
Query: 198 TFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIA-LNGQVVIRPMMYIALTYDHRL 374
+F+++N G G+L PIIN P +AI+G+H I +RPI + + + MMY++L++DHRL
Sbjct: 438 SFSVTNIGSIGALFSFPIINVPDAAIMGVHSIVKRPIVDEHDNITVAHMMYLSLSFDHRL 497
Query: 375 IDGREAVLFLRKIKEGVEDP 434
IDG EA F +++ +E+P
Sbjct: 498 IDGAEAARFCKEVIRLLENP 517
>UniRef50_Q2JA39 Cluster: Dehydrogenase subunit; n=4;
Actinomycetales|Rep: Dehydrogenase subunit - Frankia sp.
(strain CcI3)
Length = 430
Score = 124 bits (298), Expect = 3e-27
Identities = 60/139 (43%), Positives = 90/139 (64%)
Frame = +3
Query: 39 VDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNG 218
V + A TP+GLVVPV+ + Q +T A + IA L AR G LT E+ GGTFT++N
Sbjct: 292 VHLGFAAQTPRGLVVPVVHHAQGLTTARLAAEIARLTAAARAGTLTPAELTGGTFTLNNY 351
Query: 219 GVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLIDGREAVL 398
GVFG TPII+ P++A++G+ I RP A++G++ +R ++ ++ T+DHR+ DG A
Sbjct: 352 GVFGVDGSTPIIHHPEAAMIGIGRIVPRPWAVDGELAVRRIVQLSFTFDHRVCDGATAGS 411
Query: 399 FLRKIKEGVEDPATIVAGL 455
FLR + + VEDP ++ L
Sbjct: 412 FLRFVADAVEDPTVLLRHL 430
>UniRef50_Q1Q664 Cluster: Similar to 2-oxoglutarate dehydrogenase
complex E2 component; n=1; Candidatus Kuenenia
stuttgartiensis|Rep: Similar to 2-oxoglutarate
dehydrogenase complex E2 component - Candidatus Kuenenia
stuttgartiensis
Length = 416
Score = 124 bits (298), Expect = 3e-27
Identities = 60/141 (42%), Positives = 94/141 (66%), Gaps = 2/141 (1%)
Frame = +3
Query: 12 ENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMD 191
+N I+ ++Y+++ +AVA GLVVPVI++ + I +A AR+ KL +++
Sbjct: 254 DNGILQKNYINLGIAVALEDGLVVPVIKDADKKDMFQLAREIQEIAVNARSKKLKPDDVR 313
Query: 192 GGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALN--GQVVIRPMMYIALTYD 365
GGTFTI+N GV GSL GTP+I PQSAILG+ + +RP+ L + +R M+Y++L++D
Sbjct: 314 GGTFTITNYGVNGSLFGTPLILQPQSAILGVGAVVKRPVILGDADAIAVRSMVYLSLSFD 373
Query: 366 HRLIDGREAVLFLRKIKEGVE 428
HR++DG A FL K+K+ +E
Sbjct: 374 HRVMDGAHADAFLHKVKDILE 394
>UniRef50_A0JUQ7 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=9; Actinobacteria
(class)|Rep: Catalytic domain of components of various
dehydrogenase complexes - Arthrobacter sp. (strain FB24)
Length = 462
Score = 124 bits (298), Expect = 3e-27
Identities = 57/144 (39%), Positives = 91/144 (63%)
Frame = +3
Query: 18 EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGG 197
EI+ +YV++ +A ATP+GL VP I++ +M+ ++ + L E AR GK + E+ GG
Sbjct: 317 EIVQYNYVNLGIAAATPRGLTVPNIKDAHSMSLTELSTALTALTETARAGKTSPAELTGG 376
Query: 198 TFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLI 377
T +I+N GVFG GTPI+NP ++AIL M + + P +V +R +M ++L++DHRL+
Sbjct: 377 TISITNIGVFGIDAGTPILNPGEAAILAMGAVRKMPWEYRDEVALRQVMTLSLSFDHRLV 436
Query: 378 DGREAVLFLRKIKEGVEDPATIVA 449
DG + FL I + DP ++A
Sbjct: 437 DGEQGSRFLADIGAVLADPGMVLA 460
>UniRef50_Q9KG97 Cluster: Pyruvate dehydrogenase E2; n=1; Bacillus
halodurans|Rep: Pyruvate dehydrogenase E2 - Bacillus
halodurans
Length = 414
Score = 123 bits (297), Expect = 4e-27
Identities = 62/149 (41%), Positives = 92/149 (61%)
Frame = +3
Query: 9 EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEM 188
E NEI+ + I +A T KGL+VPVI+N + ++ I L+ +AR G L +++M
Sbjct: 265 ETNEIVLKKDYHIGIATDTEKGLIVPVIQNADQKSLLELAGEITQLSTQARKGTLNVQQM 324
Query: 189 DGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDH 368
G TFTISN G G L TPIIN P+ AIL +H + R + + VI+ MM ++L++DH
Sbjct: 325 TGSTFTISNVGPIGGLHATPIINYPEVAILALHKMEPRNVVREWESVIKLMMNMSLSFDH 384
Query: 369 RLIDGREAVLFLRKIKEGVEDPATIVAGL 455
RL+DG AV F ++KE +E+P ++ L
Sbjct: 385 RLVDGATAVRFTNRMKELIENPNLLLMEL 413
>UniRef50_A5UTW4 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=5; Chloroflexi (class)|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Roseiflexus sp. RS-1
Length = 434
Score = 123 bits (297), Expect = 4e-27
Identities = 66/144 (45%), Positives = 90/144 (62%), Gaps = 4/144 (2%)
Frame = +3
Query: 9 EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEM 188
++ I YR + I +AVA GL+VPV+R+ + A I + L E+AR +L +E
Sbjct: 287 DDGIITYRR-IHIGIAVALDDGLIVPVLRDADEKSLAGIARALNDLTERARMRRLQPDET 345
Query: 189 DGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQ----VVIRPMMYIAL 356
+GGTFTISN GV GSL TPI+N QS ILG+ I +RP+ + Q +VIRPM Y++L
Sbjct: 346 EGGTFTISNHGVGGSLFATPILNRGQSGILGVGAIVKRPVVITHQGSDAIVIRPMCYLSL 405
Query: 357 TYDHRLIDGREAVLFLRKIKEGVE 428
T+DHR DG A FL +KE +E
Sbjct: 406 TFDHRACDGATADAFLAAVKETLE 429
>UniRef50_Q83G30 Cluster: Dihydrolipoamide succinyltransferase
component E2; n=2; Tropheryma whipplei|Rep:
Dihydrolipoamide succinyltransferase component E2 -
Tropheryma whipplei (strain Twist) (Whipple's bacillus)
Length = 461
Score = 123 bits (296), Expect = 5e-27
Identities = 65/146 (44%), Positives = 96/146 (65%), Gaps = 5/146 (3%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEE 185
I +++I++ DY +IS+AV T +GL+ PVI+N +MT A ++ LA +AR KL+ +E
Sbjct: 310 IVDDQIVFPDYENISLAVDTERGLLTPVIKNAGDMTVAQFAKSVFDLARRARNNKLSPDE 369
Query: 186 MDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERP-IALNGQ----VVIRPMMYI 350
+ GGTFT++N G G+L TP++ PQ AILG+ I RP I L+ Q + IR + +
Sbjct: 370 LTGGTFTVTNTGSRGALFDTPVVFLPQLAILGIGAIARRPVIVLDAQGNECISIRSVAFF 429
Query: 351 ALTYDHRLIDGREAVLFLRKIKEGVE 428
AL+YDHR+IDG +A FL IK +E
Sbjct: 430 ALSYDHRVIDGADAARFLGYIKSLLE 455
>UniRef50_Q18CC2 Cluster: E2 component of acetoin dehydrogenase
enzyme system; n=2; Clostridium difficile|Rep: E2
component of acetoin dehydrogenase enzyme system -
Clostridium difficile (strain 630)
Length = 348
Score = 123 bits (296), Expect = 5e-27
Identities = 62/146 (42%), Positives = 95/146 (65%)
Frame = +3
Query: 9 EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEM 188
+E Y+D V+I++AV +GL VPV++N + +I LAEK +TGKL +
Sbjct: 203 DEGIFRYKD-VNIAIAVGLDEGLYVPVVKNANKKSLKEIAKESKELAEKVKTGKLMPADQ 261
Query: 189 DGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDH 368
+G TFTISN G++G TPIIN P SAILG+ ++ + +NG+ I+P+M ++LT DH
Sbjct: 262 EGNTFTISNVGMYGITTFTPIINMPSSAILGVGATQDKFVPVNGEAKIKPIMNLSLTSDH 321
Query: 369 RLIDGREAVLFLRKIKEGVEDPATIV 446
R+IDG A FL+ +KE +E+P +++
Sbjct: 322 RVIDGTVAAKFLKDLKELLENPLSML 347
>UniRef50_Q0SJA7 Cluster: Dihydrolipoyllysine-residue
succinyltransferase; n=1; Rhodococcus sp. RHA1|Rep:
Dihydrolipoyllysine-residue succinyltransferase -
Rhodococcus sp. (strain RHA1)
Length = 367
Score = 123 bits (296), Expect = 5e-27
Identities = 60/145 (41%), Positives = 94/145 (64%), Gaps = 4/145 (2%)
Frame = +3
Query: 18 EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGG 197
E+ Y D+ + +AV + KGL+VPVIR+ Q + + IA A+K RTG +T +++ GG
Sbjct: 219 EVTYYDHCHLGMAVDSAKGLMVPVIRDAQQLGIEGLAQAIADKADKVRTGTITADDLTGG 278
Query: 198 TFTISNGGVFGSLMGTPIINPPQSAILGMHGIFER--PIALNGQ--VVIRPMMYIALTYD 365
TFT++N G G+L TPIIN PQ+ ILG+ + ER P +G+ + +R M Y++++YD
Sbjct: 279 TFTLTNTGSRGALFDTPIINQPQTGILGVGAVVERLVPSRQDGELRIDVRSMAYLSISYD 338
Query: 366 HRLIDGREAVLFLRKIKEGVEDPAT 440
HR++DG +A FL +K +E+ T
Sbjct: 339 HRIVDGADAARFLTTVKARLENGFT 363
>UniRef50_Q9RXQ3 Cluster: Pyruvate dehydrogenase complex,
dihydrolipoamide acetyltransferase E2 component; n=4;
Deinococci|Rep: Pyruvate dehydrogenase complex,
dihydrolipoamide acetyltransferase E2 component -
Deinococcus radiodurans
Length = 617
Score = 122 bits (294), Expect = 9e-27
Identities = 68/145 (46%), Positives = 94/145 (64%), Gaps = 3/145 (2%)
Frame = +3
Query: 18 EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGG 197
++IY+++V+I VAV TP GL+VPV+++ ++ L ++ LA +AR KL +EM G
Sbjct: 472 QVIYKEFVNIGVAVDTPVGLLVPVVKDADRKGITELVLDLSELAGRARERKLKPDEMQGA 531
Query: 198 TFTISNGGVFGSLMGTPIINPPQSAILGM-HGIFERPI--ALNGQVVIRPMMYIALTYDH 368
TFTISN G G TPI+N P+ AILG+ G FE P+ G+ R M+ ++LTYDH
Sbjct: 532 TFTISNLGGIGGNAFTPIVNSPEVAILGVSRGGFE-PVWNKEKGEFEPRNMLPLSLTYDH 590
Query: 369 RLIDGREAVLFLRKIKEGVEDPATI 443
RLIDG +A FLR I E +EDP I
Sbjct: 591 RLIDGADAARFLRYICESLEDPFLI 615
>UniRef50_Q6MPR6 Cluster: Pyruvate dehydrogenase E2; n=1;
Bdellovibrio bacteriovorus|Rep: Pyruvate dehydrogenase
E2 - Bdellovibrio bacteriovorus
Length = 543
Score = 122 bits (294), Expect = 9e-27
Identities = 62/146 (42%), Positives = 86/146 (58%)
Frame = +3
Query: 18 EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGG 197
EI+Y+ Y ++ A TP GLVVPVI+N + +I I L+++AR GKL +EM G
Sbjct: 397 EIVYKKYFNLGFAADTPNGLVVPVIKNADQKSILEISKEILDLSKRARDGKLKPDEMKGA 456
Query: 198 TFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLI 377
T T++N G G TP+IN P+ AILGM+ I E+ + NGQV +M +T DHRLI
Sbjct: 457 TITVTNIGSIGGTYATPVINHPEVAILGMYKIDEKVVLKNGQVSAIKVMNYTMTADHRLI 516
Query: 378 DGREAVLFLRKIKEGVEDPATIVAGL 455
DG A FL +E+P ++ L
Sbjct: 517 DGAVAARFLAAFIGRIENPGKLLVEL 542
>UniRef50_Q48TW1 Cluster: Dihydrolipoamide acetyltransferase
component of pyruvate dehydrogenase complex; n=41;
Streptococcus|Rep: Dihydrolipoamide acetyltransferase
component of pyruvate dehydrogenase complex -
Streptococcus pyogenes serotype M28
Length = 469
Score = 122 bits (293), Expect = 1e-26
Identities = 58/142 (40%), Positives = 87/142 (61%)
Frame = +3
Query: 9 EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEM 188
+ N+I +V++ +AV GL+VPVI M+ +D L + +KA+TGKL EM
Sbjct: 323 DANDIELHRFVNLGIAVGLDDGLIVPVIHGADKMSLSDFVLASKDVIKKAQTGKLKAAEM 382
Query: 189 DGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDH 368
G TF+I+N G+FG+ PIIN P SAILG+ P ++G++V RP+M + LT DH
Sbjct: 383 SGSTFSITNLGMFGTKTFNPIINQPNSAILGVGATIPTPTVVDGEIVARPIMAMCLTIDH 442
Query: 369 RLIDGREAVLFLRKIKEGVEDP 434
RL+DG F+ +K+ +E+P
Sbjct: 443 RLVDGMNGAKFMVDLKKLMENP 464
>UniRef50_Q97Y19 Cluster: Dihydrolipoamide S-acetyltransferase,
carboxy-end; n=2; cellular organisms|Rep:
Dihydrolipoamide S-acetyltransferase, carboxy-end -
Sulfolobus solfataricus
Length = 177
Score = 122 bits (293), Expect = 1e-26
Identities = 62/142 (43%), Positives = 92/142 (64%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEE 185
+E ++I + V+I +AVA +GL+VPVIRN +I LA+KAR KL +E
Sbjct: 27 LEGDQIKIIEEVNIGIAVALDQGLIVPVIRNADTKPITEIAKESHELADKARENKLNPDE 86
Query: 186 MDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYD 365
+ GGTFTISN G++ TPIINPPQ+AILG+ I P+ + + I +M+++LT+D
Sbjct: 87 VSGGTFTISNLGMYDIDSFTPIINPPQTAILGVGRIRRAPVVVGDNISIGYIMWLSLTFD 146
Query: 366 HRLIDGREAVLFLRKIKEGVED 431
HR++DG A FL+++ E +ED
Sbjct: 147 HRVMDGHTAAKFLKELTEILED 168
>UniRef50_A5MZI5 Cluster: PdhC; n=6; Clostridium|Rep: PdhC -
Clostridium kluyveri DSM 555
Length = 444
Score = 121 bits (292), Expect = 2e-26
Identities = 59/147 (40%), Positives = 94/147 (63%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEE 185
I + I +DYV++ VAVA +GL+VPV+++ I + +KA++ L+ ++
Sbjct: 297 ISGGKFILKDYVNMGVAVALDEGLIVPVVKDTDIKGLKQIAEEFKEIVKKAKSNSLSPDD 356
Query: 186 MDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYD 365
M GGTFTI+N G+ G +PIIN P+ AILG++ I + P+ ++V++P+M ++LT D
Sbjct: 357 MTGGTFTITNLGMLGIDSFSPIINQPEVAILGVNTIVDTPVVEGEKIVVKPLMKLSLTAD 416
Query: 366 HRLIDGREAVLFLRKIKEGVEDPATIV 446
HR IDG A FL+KIKE +E P ++
Sbjct: 417 HRAIDGAYAAKFLQKIKEYIEKPELLL 443
>UniRef50_Q49110 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=3; Mollicutes|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex - Mycoplasma
capricolum subsp. capricolum (strain California kid /
ATCC27343 / NCTC 10154)
Length = 438
Score = 121 bits (291), Expect = 2e-26
Identities = 60/143 (41%), Positives = 94/143 (65%)
Frame = +3
Query: 15 NEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDG 194
N+I + ++I +AV TP GL+VPVI+ +++ +I + I+ LA KA+ GKLT EM
Sbjct: 294 NKIQFMHNINIGIAVDTPNGLMVPVIKGADHLSVFEIAIKISELANKAKDGKLTRAEMTE 353
Query: 195 GTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRL 374
TFT+SN G G TPIIN P+SAILG+ + + P+ +NG++ R +M +++T DHR+
Sbjct: 354 ATFTVSNFGSVGLDYATPIINSPESAILGVGTMSQTPLYINGELQKRFIMPLSMTCDHRI 413
Query: 375 IDGREAVLFLRKIKEGVEDPATI 443
IDG +A FL K+++ + P +
Sbjct: 414 IDGADAGRFLIKVQDYLSKPVLL 436
>UniRef50_A0LLM2 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Syntrophobacter
fumaroxidans MPOB|Rep: Catalytic domain of components of
various dehydrogenase complexes - Syntrophobacter
fumaroxidans (strain DSM 10017 / MPOB)
Length = 443
Score = 120 bits (290), Expect = 3e-26
Identities = 61/150 (40%), Positives = 93/150 (62%), Gaps = 4/150 (2%)
Frame = +3
Query: 9 EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEM 188
E EI+++ Y +I VAV T +GL+VPVIR+V + ++ + + +AE+ R GK EEM
Sbjct: 291 EREEIVFKRYYNIGVAVDTDRGLIVPVIRDVDRKSVRELAVELLDVAERTRRGKAEREEM 350
Query: 189 DGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNG----QVVIRPMMYIAL 356
GGTFT++N G G TPIIN PQSAILGM +P+ ++V R ++ + +
Sbjct: 351 TGGTFTLTNIGALGGTAFTPIINHPQSAILGMGQARLQPVVRGDLERHEIVPRLLLPLIV 410
Query: 357 TYDHRLIDGREAVLFLRKIKEGVEDPATIV 446
+DHR++DG +A FL I E +E+P ++
Sbjct: 411 AFDHRIVDGADAARFLGMIIEALENPEELL 440
>UniRef50_Q9I1M0 Cluster: Lipoamide acyltransferase component of
branched-chain alpha-keto acid dehydrogenase complex (EC
2.3.1.168) (Dihydrolipoyllysine-residue (2-
methylpropanoyl)transferase); n=22; Proteobacteria|Rep:
Lipoamide acyltransferase component of branched-chain
alpha-keto acid dehydrogenase complex (EC 2.3.1.168)
(Dihydrolipoyllysine-residue (2-
methylpropanoyl)transferase) - Pseudomonas aeruginosa
Length = 428
Score = 120 bits (289), Expect = 4e-26
Identities = 55/146 (37%), Positives = 96/146 (65%), Gaps = 1/146 (0%)
Frame = +3
Query: 9 EENEIIYR-DYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEE 185
+E E++ R V + +A + GL+VPV+R+ ++ +A LAE AR+GK +E
Sbjct: 280 DEAEVVTRYGAVHVGIATQSDNGLMVPVLRHAESRDLWGNASEVARLAEAARSGKAQRQE 339
Query: 186 MDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYD 365
+ G T T+S+ GV G ++ TP+IN P+ AI+G++ I ERP+ + G +V+R MM ++ ++D
Sbjct: 340 LSGSTITLSSLGVLGGIVSTPVINHPEVAIVGVNRIVERPMVVGGNIVVRKMMNLSSSFD 399
Query: 366 HRLIDGREAVLFLRKIKEGVEDPATI 443
HR++DG +A F++ ++ +E PAT+
Sbjct: 400 HRVVDGMDAAAFIQAVRGLLEHPATL 425
>UniRef50_Q5EIH5 Cluster: Dihydrolipoamide succinyltransferase
component E2; n=2; Novosphingobium aromaticivorans|Rep:
Dihydrolipoamide succinyltransferase component E2 -
Sphingomonas aromaticivorans
Length = 406
Score = 120 bits (288), Expect = 5e-26
Identities = 58/146 (39%), Positives = 93/146 (63%), Gaps = 5/146 (3%)
Frame = +3
Query: 12 ENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMD 191
E+ ++ V + +AV TP+GLVVPV+RN +++ + IA LA+KAR G L ++M+
Sbjct: 261 EDAMVQFGAVHLGIAVDTPEGLVVPVVRNAESLNARGLTDAIAALADKARAGTLRPQDME 320
Query: 192 GGTFTISNGGVFGSLM-GTPIINPPQSAILGMHGIFERPIALNG----QVVIRPMMYIAL 356
GGTFTISN G G ++ ++NPPQ A+LG+ GI P+A+ + +RP++ ++L
Sbjct: 321 GGTFTISNPGSMGPVVRAEALLNPPQVALLGLPGIVRAPVAIKDGDAWAMAVRPLLRLSL 380
Query: 357 TYDHRLIDGREAVLFLRKIKEGVEDP 434
++DHR +DG + FL +K +E P
Sbjct: 381 SFDHRALDGGPVIAFLNTLKATLERP 406
>UniRef50_A7HBV2 Cluster: Dehydrogenase complex catalytic domain;
n=2; Anaeromyxobacter|Rep: Dehydrogenase complex
catalytic domain - Anaeromyxobacter sp. Fw109-5
Length = 454
Score = 120 bits (288), Expect = 5e-26
Identities = 54/142 (38%), Positives = 86/142 (60%)
Frame = +3
Query: 9 EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEM 188
E E++ D+ +A AT GLVVPV+R + ++ I LA+ A+ G+ E+M
Sbjct: 305 ERGELVLHRRYDVGIASATDAGLVVPVVRGADRRSLVELAREIERLAQDAKAGRARPEDM 364
Query: 189 DGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDH 368
TFTI++ G G + TP++N P+ ILG+H I P+ +GQVV+R +M++++T DH
Sbjct: 365 GRSTFTITSLGALGGMFATPVLNYPEVGILGVHRIRPTPVVRDGQVVVRDVMHVSVTSDH 424
Query: 369 RLIDGREAVLFLRKIKEGVEDP 434
R++DG EA F ++ +EDP
Sbjct: 425 RVVDGHEAAAFCYEVIRTLEDP 446
>UniRef50_Q9HN75 Cluster: Dihydrolipoamide S-acetyltransferase; n=1;
Halobacterium salinarum|Rep: Dihydrolipoamide
S-acetyltransferase - Halobacterium salinarium
(Halobacterium halobium)
Length = 478
Score = 120 bits (288), Expect = 5e-26
Identities = 60/146 (41%), Positives = 89/146 (60%)
Frame = +3
Query: 9 EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEM 188
++ EI + +I VAVAT GL+VPV+ +V + +I + L E+AR + +M
Sbjct: 331 DDEEIALKQDYNIGVAVATDAGLMVPVVEHVDQKSMLEISTEMNDLVEQARERSIAPADM 390
Query: 189 DGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDH 368
DGGTFTI+N G G TPIIN P++AILG+ I ERP+A +G V + ++L+ DH
Sbjct: 391 DGGTFTITNFGAIGGEYATPIINYPETAILGLGAIDERPVAEDGDVRAAQTLPLSLSIDH 450
Query: 369 RLIDGREAVLFLRKIKEGVEDPATIV 446
R+IDG EA F ++ E + DP ++
Sbjct: 451 RVIDGAEAAQFTNRVMEYLTDPELLL 476
>UniRef50_Q9X6X2 Cluster: Lipoamide acyltransferase; n=3;
Cystobacterineae|Rep: Lipoamide acyltransferase -
Myxococcus xanthus
Length = 416
Score = 119 bits (287), Expect = 6e-26
Identities = 61/139 (43%), Positives = 87/139 (62%)
Frame = +3
Query: 18 EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGG 197
E++ R +I +A ATP GL V V+++ +T A++ A L AR KL +EE+ GG
Sbjct: 270 ELVVRGEFNIGMAAATPDGLTVAVVKSADRLTLAELARETARLGAAARDRKLKMEELTGG 329
Query: 198 TFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLI 377
TFTIS+ G G L TPIIN P+ ILG+H + +RP + QVV+R MM ++L+ DHR+I
Sbjct: 330 TFTISSLGQSGGLFATPIINHPEVGILGVHRLKKRPAVVGDQVVVRDMMNLSLSCDHRVI 389
Query: 378 DGREAVLFLRKIKEGVEDP 434
DG A F +I + +E P
Sbjct: 390 DGSVAADFTYEIIKYLEKP 408
>UniRef50_A1UIB1 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=4; Actinomycetales|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Mycobacterium sp. (strain KMS)
Length = 629
Score = 119 bits (286), Expect = 9e-26
Identities = 63/146 (43%), Positives = 91/146 (62%), Gaps = 5/146 (3%)
Frame = +3
Query: 9 EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEM 188
+ EI Y D + AV T +GL+ PVI+N +++ A + IA +A +AR+G L +E+
Sbjct: 475 DTKEITYYDAEHLGFAVDTDQGLLSPVIKNAGDLSLAGLARAIADIAARARSGDLKPDEL 534
Query: 189 DGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIAL-----NGQVVIRPMMYIA 353
GGTFTI+N G G+L TPI+ PPQ+A+LG I +RP + N + +R + Y+
Sbjct: 535 SGGTFTITNIGSQGALFDTPILVPPQAAMLGTGAIVKRPRVIVDEFGNESIGVRSICYLP 594
Query: 354 LTYDHRLIDGREAVLFLRKIKEGVED 431
LTYDHRLIDG +A FL IK +E+
Sbjct: 595 LTYDHRLIDGADAGRFLTTIKRRLEE 620
>UniRef50_P21883 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=80; Bacilli|Rep: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex - Bacillus subtilis
Length = 442
Score = 118 bits (285), Expect = 1e-25
Identities = 61/144 (42%), Positives = 89/144 (61%)
Frame = +3
Query: 15 NEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDG 194
+E+I + Y +I +A T KGL+VPV++N + +I I GLA KAR GKL EM G
Sbjct: 296 DEVIQKHYFNIGIAADTEKGLLVPVVKNADRKSVFEISDEINGLATKAREGKLAPAEMKG 355
Query: 195 GTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRL 374
+ TI+N G G TP+IN P+ AILG+ I E+ I +G++V P++ ++L++DHR+
Sbjct: 356 ASCTITNIGSAGGQWFTPVINHPEVAILGIGRIAEKAIVRDGEIVAAPVLALSLSFDHRM 415
Query: 375 IDGREAVLFLRKIKEGVEDPATIV 446
IDG A L IK + DP I+
Sbjct: 416 IDGATAQNALNHIKRLLNDPQLIL 439
>UniRef50_Q67RX4 Cluster: Putative uncharacterized protein; n=1;
Symbiobacterium thermophilum|Rep: Putative
uncharacterized protein - Symbiobacterium thermophilum
Length = 262
Score = 118 bits (284), Expect = 1e-25
Identities = 58/136 (42%), Positives = 85/136 (62%), Gaps = 2/136 (1%)
Frame = +3
Query: 36 YVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISN 215
Y+++ +A A P G+++PV+ + M + D+ I +KAR G L+ E+ G TF I+N
Sbjct: 126 YINLGIATAVPGGVLLPVVPGAERMGFWDLARAIHLQTQKARAGLLSPHELSGHTFVITN 185
Query: 216 GGVFG-SLMGTPIINPPQSAILGMHGIFERPIAL-NGQVVIRPMMYIALTYDHRLIDGRE 389
G +G +L GTPII PP IL I +RP+ + + Q+ IRPMMY+ALT DHR +DG E
Sbjct: 186 TGRYGATLFGTPIIQPPNVGILAFEAIQKRPVVVGDDQLAIRPMMYLALTADHRAVDGAE 245
Query: 390 AVLFLRKIKEGVEDPA 437
+ FL +KE +E A
Sbjct: 246 MIGFLATVKEALEQVA 261
>UniRef50_Q65MC9 Cluster: AcoC; n=1; Bacillus licheniformis ATCC
14580|Rep: AcoC - Bacillus licheniformis (strain DSM 13
/ ATCC 14580)
Length = 377
Score = 118 bits (284), Expect = 1e-25
Identities = 55/148 (37%), Positives = 94/148 (63%)
Frame = +3
Query: 3 VIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIE 182
V ++ + ++V + VA A +GL VPVIR+ + + ++ I A+KAR G+L +
Sbjct: 229 VYQDGRLATFEHVHLGVAAALDEGLAVPVIRHAERLPLIELAKKIKWYAKKAREGRLLHD 288
Query: 183 EMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTY 362
E++G TFTI+N G +G TPI+NPP++ ILG+ ++ P+ +G++ ++ ++LT+
Sbjct: 289 EIEGSTFTITNLGAYGVEHFTPILNPPETGILGVGQMYSAPVYQDGELTKGAILPLSLTF 348
Query: 363 DHRLIDGREAVLFLRKIKEGVEDPATIV 446
DHR +DG A FL +K +EDPA+I+
Sbjct: 349 DHRALDGAPAAAFLSDVKNYLEDPASIL 376
>UniRef50_Q0SGE5 Cluster: Dihydrolipoyllysine-residue
succinyltransferase; n=3; Actinomycetales|Rep:
Dihydrolipoyllysine-residue succinyltransferase -
Rhodococcus sp. (strain RHA1)
Length = 417
Score = 118 bits (284), Expect = 1e-25
Identities = 55/149 (36%), Positives = 94/149 (63%)
Frame = +3
Query: 9 EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEM 188
E EI+ + YV++ +A ATP+GLVVP I+ Q+++ ++ I L AR+G+ ++
Sbjct: 269 ENQEIVTKHYVNLGIAAATPRGLVVPNIKEAQSLSLLELCRAITELTATARSGRAEPAQL 328
Query: 189 DGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDH 368
GGT +I+N GVFG GTPI+NP +SAIL + + RP ++ +R + +++++DH
Sbjct: 329 TGGTVSITNVGVFGVDAGTPILNPGESAILCLGSVTRRPWVHEDELAVRWVTTLSVSFDH 388
Query: 369 RLIDGREAVLFLRKIKEGVEDPATIVAGL 455
R++DG + FL + + DPA+++A L
Sbjct: 389 RVVDGEQGSRFLSSVAAMLHDPASLLAHL 417
>UniRef50_O32959 Cluster: Dihydrolipoamide succinyltransferase; n=1;
Mycobacterium leprae|Rep: Dihydrolipoamide
succinyltransferase - Mycobacterium leprae
Length = 530
Score = 117 bits (282), Expect = 3e-25
Identities = 63/148 (42%), Positives = 90/148 (60%), Gaps = 5/148 (3%)
Frame = +3
Query: 9 EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEM 188
+ EI Y D + A+ T KGL+ PVI +++ A + I +A +AR+G L EE+
Sbjct: 376 DTKEITYYDAEHLGFAIDTDKGLLSPVIHYAGDLSLAGLARAIVDIAARARSGNLKPEEL 435
Query: 189 DGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIAL-----NGQVVIRPMMYIA 353
GGTFTI+N G G+L TPI+ PPQ+A+LG+ I +RP + N + +R + Y+
Sbjct: 436 SGGTFTITNIGSQGALFDTPILVPPQAAMLGIGAIVKRPRVVIDASGNESIGVRAICYLP 495
Query: 354 LTYDHRLIDGREAVLFLRKIKEGVEDPA 437
LTYDHRLIDG +A FL IK +E+ A
Sbjct: 496 LTYDHRLIDGADAGRFLTTIKHRLEEGA 523
>UniRef50_Q1AZ52 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Rubrobacter xylanophilus
DSM 9941|Rep: Catalytic domain of components of various
dehydrogenase complexes - Rubrobacter xylanophilus
(strain DSM 9941 / NBRC 16129)
Length = 396
Score = 117 bits (282), Expect = 3e-25
Identities = 54/141 (38%), Positives = 93/141 (65%)
Frame = +3
Query: 12 ENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMD 191
+ EI+ + V++SVAVAT GL+VPV+R Q + ++ + + E+AR+G+L+ E+
Sbjct: 252 DGEILLYEDVNVSVAVATGSGLLVPVVRWAQALELGELAARLREVLERARSGRLSAEDTA 311
Query: 192 GGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHR 371
GGT T+SN G++G GTP++ PQ+A++ I ERP A++G+V +RP + +++ +DHR
Sbjct: 312 GGTITLSNLGMYGIEGGTPLVTHPQAAVVFAGAIVERPWAVSGRVEVRPTLTLSVGFDHR 371
Query: 372 LIDGREAVLFLRKIKEGVEDP 434
++DG A F ++ +E P
Sbjct: 372 ILDGVAAARFTTALRRRLESP 392
>UniRef50_Q14PD7 Cluster: Putative dihydrolipoyllysine-residue
acetyltransferase component e2 of pyruvate dehydrogenase
protein; n=1; Spiroplasma citri|Rep: Putative
dihydrolipoyllysine-residue acetyltransferase component
e2 of pyruvate dehydrogenase protein - Spiroplasma citri
Length = 427
Score = 117 bits (282), Expect = 3e-25
Identities = 63/147 (42%), Positives = 90/147 (61%), Gaps = 1/147 (0%)
Frame = +3
Query: 9 EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEM 188
E+ EII++DY +I +A TP GL+VPV++ V + I I LA K R KL +EM
Sbjct: 280 EQQEIIFKDYYNIGMATDTPTGLMVPVVKGVDQLNIMQIAKMINDLATKTRERKLKPDEM 339
Query: 189 DGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERP-IALNGQVVIRPMMYIALTYD 365
GTFTI+N G G TP+IN P+ AILG+ I + P I N ++ I ++ ++LT D
Sbjct: 340 KDGTFTITNFGSAGIEFATPVINFPEVAILGVGIIKKAPVINKNNEIEISSILPLSLTID 399
Query: 366 HRLIDGREAVLFLRKIKEGVEDPATIV 446
HRLIDG + FL ++ E +E PA ++
Sbjct: 400 HRLIDGADGGRFLARVTELLESPALLL 426
>UniRef50_Q9PKE7 Cluster: Pyruvate dehydrogenase, E2 component,
dihydrolipoamide acetyltransferase, putative; n=2;
Chlamydiales|Rep: Pyruvate dehydrogenase, E2 component,
dihydrolipoamide acetyltransferase, putative - Chlamydia
muridarum
Length = 428
Score = 117 bits (281), Expect = 3e-25
Identities = 57/145 (39%), Positives = 89/145 (61%)
Frame = +3
Query: 12 ENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMD 191
+N II +DIS+AVA P G++ P+IR I I GLA +AR L EE
Sbjct: 282 DNTIIRFSTIDISIAVAIPDGVITPIIRCADRKNVGTISAEIKGLAARARQFSLKEEEYK 341
Query: 192 GGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHR 371
GG+F ISN G+ G T I+NPPQ+AIL + + E+P+ LNG++ + + L+ DHR
Sbjct: 342 GGSFCISNLGMTGISDFTAILNPPQAAILAVGSVEEQPVVLNGELAVGSTCMLTLSVDHR 401
Query: 372 LIDGREAVLFLRKIKEGVEDPATIV 446
+IDG A +F++++++ +E P+ ++
Sbjct: 402 VIDGYPAAMFMKRLQKLLEAPSVLL 426
>UniRef50_Q67SE5 Cluster: Pyruvate dehydrogenase E2; n=1;
Symbiobacterium thermophilum|Rep: Pyruvate dehydrogenase
E2 - Symbiobacterium thermophilum
Length = 450
Score = 117 bits (281), Expect = 3e-25
Identities = 61/146 (41%), Positives = 85/146 (58%)
Frame = +3
Query: 9 EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEM 188
E EI+ I A+ T GL+VPVI++ I + L + R GKL +EM
Sbjct: 301 EAQEIVLHKRYHIGFALDTDAGLLVPVIKDADRKPVFAIAQEMNDLIARGREGKLAPDEM 360
Query: 189 DGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDH 368
G TFTISN G G L TP+IN P+ AILG+ RP+ +G++VIR M ++AL++DH
Sbjct: 361 RGSTFTISNQGSIGGLFFTPVINYPEVAILGIGKTQPRPVVRDGEIVIRQMAHLALSFDH 420
Query: 369 RLIDGREAVLFLRKIKEGVEDPATIV 446
RLIDG A FL ++ E + DP ++
Sbjct: 421 RLIDGGMATRFLNRLAELLSDPTLLM 446
>UniRef50_P65634 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=12; Bacteria|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Mycobacterium bovis
Length = 553
Score = 117 bits (281), Expect = 3e-25
Identities = 63/148 (42%), Positives = 91/148 (61%), Gaps = 5/148 (3%)
Frame = +3
Query: 9 EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEM 188
+ EI Y D + AV T +GL+ PVI + +++ A + IA +A +AR+G L +E+
Sbjct: 399 DTKEITYYDAEHLGFAVDTEQGLLSPVIHDAGDLSLAGLARAIADIAARARSGNLKPDEL 458
Query: 189 DGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIAL-----NGQVVIRPMMYIA 353
GGTFTI+N G G+L TPI+ PPQ+A+LG I +RP + N + +R + Y+
Sbjct: 459 SGGTFTITNIGSQGALFDTPILVPPQAAMLGTGAIVKRPRVVVDASGNESIGVRSVCYLP 518
Query: 354 LTYDHRLIDGREAVLFLRKIKEGVEDPA 437
LTYDHRLIDG +A FL IK +E+ A
Sbjct: 519 LTYDHRLIDGADAGRFLTTIKHRLEEGA 546
>UniRef50_O31550 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of acetoin cleaving system;
n=13; Bacillus|Rep: Dihydrolipoyllysine-residue
acetyltransferase component of acetoin cleaving system -
Bacillus subtilis
Length = 398
Score = 117 bits (281), Expect = 3e-25
Identities = 57/146 (39%), Positives = 94/146 (64%), Gaps = 1/146 (0%)
Frame = +3
Query: 12 ENE-IIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEM 188
+NE II +V + +AVA GLVVPVIR+ + ++ ++ +I+ A+KAR G+ EE+
Sbjct: 252 QNERIITHPHVHLGMAVALENGLVVPVIRHAEKLSLIELAQSISENAKKAREGRAGSEEL 311
Query: 189 DGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDH 368
G TF+I+N G FG TPI+NPP++ ILG+ ++ P+ ++V ++ ++LT+DH
Sbjct: 312 QGSTFSITNLGAFGVEHFTPILNPPETGILGIGASYDTPVYQGEEIVRSTILPLSLTFDH 371
Query: 369 RLIDGREAVLFLRKIKEGVEDPATIV 446
R DG A FL+ +K +E+PA ++
Sbjct: 372 RACDGAPAAAFLKAMKTYLEEPAALI 397
>UniRef50_O84249 Cluster: Dihydrolipoamide Acetyltransferase; n=7;
Chlamydiaceae|Rep: Dihydrolipoamide Acetyltransferase -
Chlamydia trachomatis
Length = 429
Score = 116 bits (278), Expect = 8e-25
Identities = 55/145 (37%), Positives = 89/145 (61%)
Frame = +3
Query: 12 ENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMD 191
+N+II +DIS+AVA P G++ P++R I I GLA KA+ L EE
Sbjct: 283 DNKIIRFSTIDISIAVAIPDGVIAPIVRCADRKNIGMISAEIKGLATKAKQQSLAEEEYK 342
Query: 192 GGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHR 371
GG+F +SN G+ G T I+NPPQ+AIL + + E+P+ LNG++ + + L+ DHR
Sbjct: 343 GGSFCVSNLGMTGISDFTAILNPPQAAILAVGSVEEQPVVLNGELAVGLTCMLTLSVDHR 402
Query: 372 LIDGREAVLFLRKIKEGVEDPATIV 446
+IDG A +F+++++ +E P+ ++
Sbjct: 403 VIDGYPAAMFMKRLQRLLEAPSVLL 427
>UniRef50_A4XEQ9 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=2; Sphingomonadaceae|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Novosphingobium aromaticivorans (strain DSM
12444)
Length = 480
Score = 116 bits (278), Expect = 8e-25
Identities = 57/139 (41%), Positives = 83/139 (59%), Gaps = 1/139 (0%)
Frame = +3
Query: 36 YVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISN 215
+ D+++AVA+PKGLV P++R M A I T L +KA+ G+L E+MDGGTF++SN
Sbjct: 342 HADVAIAVASPKGLVTPIVRQADRMHIAQIAATTRALIDKAQAGRLGYEDMDGGTFSVSN 401
Query: 216 GGVFGSLMGTPIINPPQSAILGMHGIFERPI-ALNGQVVIRPMMYIALTYDHRLIDGREA 392
G+FG IINPPQ AIL + G+ + A NG + + + ++ DHR IDG
Sbjct: 402 LGMFGIEQFDAIINPPQGAILAVGGVNRVAVEAANGDIAFENRIQLTMSVDHRAIDGAAG 461
Query: 393 VLFLRKIKEGVEDPATIVA 449
FL+ +K +E P + A
Sbjct: 462 AKFLQTLKGLLEAPEGLFA 480
>UniRef50_Q5ZVD7 Cluster: Pyruvate dehydrogenase E2 component; n=5;
Legionellales|Rep: Pyruvate dehydrogenase E2 component -
Legionella pneumophila subsp. pneumophila (strain
Philadelphia 1 /ATCC 33152 / DSM 7513)
Length = 550
Score = 115 bits (277), Expect = 1e-24
Identities = 61/129 (47%), Positives = 82/129 (63%)
Frame = +3
Query: 21 IIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGT 200
+IY+ Y +I +AV TP GLVVPVI+NV ++ DI ++ L+ KAR LT +M GG
Sbjct: 408 LIYKKYYNIGIAVDTPNGLVVPVIKNVDKLSVIDIAKEMSRLSTKAREKGLTPIDMSGGC 467
Query: 201 FTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLID 380
FTIS+ G G TPI+N P+ AILG+ +PI N + R M+ I+L+YDHR+ID
Sbjct: 468 FTISSLGGIGGTAFTPIVNSPEVAILGLSRSIIKPIYDNKEFKPRLMLPISLSYDHRVID 527
Query: 381 GREAVLFLR 407
G EA F R
Sbjct: 528 GAEAARFTR 536
>UniRef50_A6DTS5 Cluster: Pyruvate dehydrogenase complex , E2
component, dihydrolipoamide acetyltransferase; n=1;
Lentisphaera araneosa HTCC2155|Rep: Pyruvate
dehydrogenase complex , E2 component, dihydrolipoamide
acetyltransferase - Lentisphaera araneosa HTCC2155
Length = 442
Score = 115 bits (277), Expect = 1e-24
Identities = 60/145 (41%), Positives = 91/145 (62%), Gaps = 1/145 (0%)
Frame = +3
Query: 15 NEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDG 194
++I+ + VDISVAV+ P GL+ P++R+ + A I + L KAR+ L+ EE G
Sbjct: 297 DKIVQFNDVDISVAVSIPDGLITPIVRSADSKGLASISKDVKSLVGKARSNSLSPEEYQG 356
Query: 195 GTFTISNGGVFGSLMG-TPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHR 371
G+FTISN G+FG++ T I+NPPQSAIL + G E +NG+V + + +T DHR
Sbjct: 357 GSFTISNLGMFGAVDSFTAILNPPQSAILAVAGTQEELKLVNGEVKSAKVCKMTITCDHR 416
Query: 372 LIDGREAVLFLRKIKEGVEDPATIV 446
+IDG A F+ +K+ +E PA ++
Sbjct: 417 VIDGALAAEFMNALKDYLETPAKLI 441
>UniRef50_A0JZU9 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=2; Micrococcineae|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Arthrobacter sp. (strain FB24)
Length = 518
Score = 115 bits (277), Expect = 1e-24
Identities = 55/149 (36%), Positives = 89/149 (59%)
Frame = +3
Query: 9 EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEM 188
E EI+ D +++ A T +GL+VP +RN M+ +++ I L R GK T E+
Sbjct: 370 ESQEIVAFDGINLGFAAQTDRGLMVPSVRNAGKMSARELDAEIRRLTAVVREGKATPSEL 429
Query: 189 DGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDH 368
GTFT++N GVFG IIN P+ ILG+ I ++P +NG++ +R + + LT+DH
Sbjct: 430 GSGTFTLNNYGVFGVDGSAAIINHPEVGILGVGRIIDKPWVVNGELAVRKVTELTLTFDH 489
Query: 369 RLIDGREAVLFLRKIKEGVEDPATIVAGL 455
R+ DG A FLR + + +E+P +++A +
Sbjct: 490 RVCDGGTAGGFLRYVADAIENPGSVLADM 518
>UniRef50_A0LQU7 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Acidothermus
cellulolyticus 11B|Rep: Catalytic domain of components
of various dehydrogenase complexes - Acidothermus
cellulolyticus (strain ATCC 43068 / 11B)
Length = 546
Score = 115 bits (276), Expect = 1e-24
Identities = 60/148 (40%), Positives = 91/148 (61%), Gaps = 1/148 (0%)
Frame = +3
Query: 15 NEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDG 194
+EI+ R YV++ +A ATP+GLVVP I++ ++ D+ I LA AR G+ + ++
Sbjct: 399 DEIVVRHYVNLGIATATPRGLVVPNIKDADRLSLIDLARAINELAATAREGRTPLAQLRN 458
Query: 195 GTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRL 374
GTFTI+N GVFG GTPIINP ++AIL + + P + V R + + L++DHR+
Sbjct: 459 GTFTITNVGVFGVDTGTPIINPGEAAILALGTVRRAPWLYHDAVQPRWVTTLGLSFDHRI 518
Query: 375 IDGREAVLFLRKIKEGVEDP-ATIVAGL 455
IDG FLR + +EDP A ++A +
Sbjct: 519 IDGDLGSRFLRDVAAFLEDPGAALLAAV 546
>UniRef50_Q92HK7 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=10; Rickettsia|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex - Rickettsia conorii
Length = 412
Score = 115 bits (276), Expect = 1e-24
Identities = 59/145 (40%), Positives = 84/145 (57%)
Frame = +3
Query: 12 ENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMD 191
E+ I Y + VDISVAVA GLV P+++N ++ + L +KA+ KLT EE
Sbjct: 267 EDAIRYYNNVDISVAVAIENGLVTPIVKNANQKNILELSREMKALIKKAKDNKLTPEEFQ 326
Query: 192 GGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHR 371
GG FTISN G++G IINPPQS I+G+ +R I N Q+ I +M + L+ DHR
Sbjct: 327 GGGFTISNLGMYGIKNFNAIINPPQSCIMGVGASAKRAIVKNDQITIATIMDVTLSADHR 386
Query: 372 LIDGREAVLFLRKIKEGVEDPATIV 446
++DG FL K+ +E P ++
Sbjct: 387 VVDGAVGAEFLVAFKKFIESPVLML 411
>UniRef50_Q92BY1 Cluster: Lin1411 protein; n=15; Bacillales|Rep:
Lin1411 protein - Listeria innocua
Length = 416
Score = 114 bits (275), Expect = 2e-24
Identities = 58/138 (42%), Positives = 88/138 (63%)
Frame = +3
Query: 15 NEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDG 194
++II ++IS+A+A L VPVI+N + I I+ LA KAR GKL+ +M+G
Sbjct: 269 DKIIEHANINISIAIAAGDLLYVPVIKNADEKSIKGIAREISELAGKARNGKLSQADMEG 328
Query: 195 GTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRL 374
GTFT+++ G FGS+ IIN PQ+AIL + I +RP+ ++ + +R M+ + L+ DHR+
Sbjct: 329 GTFTVNSTGSFGSVQSMGIINHPQAAILQVESIVKRPVIIDDMIAVRDMVNLCLSIDHRI 388
Query: 375 IDGREAVLFLRKIKEGVE 428
+DG A FL+ IK VE
Sbjct: 389 LDGLLAGKFLQAIKANVE 406
>UniRef50_Q8YDW4 Cluster: DIHYDROLIPOAMIDE ACETYLTRANSFERASE
COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX; n=11;
Proteobacteria|Rep: DIHYDROLIPOAMIDE ACETYLTRANSFERASE
COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX - Brucella
melitensis
Length = 421
Score = 114 bits (274), Expect = 2e-24
Identities = 58/136 (42%), Positives = 80/136 (58%)
Frame = +3
Query: 39 VDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNG 218
VDI+VAVAT GL+ P+IR+ M+ I + LA +AR +L EE GG F+ISN
Sbjct: 285 VDIAVAVATEGGLITPIIRSADQMSLGAISAQMKSLAARARENRLKPEEFQGGGFSISNL 344
Query: 219 GVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLIDGREAVL 398
++G + IINPPQSAIL + RPI NG++ MM + L+ DHR +DG
Sbjct: 345 SMYGVKSFSAIINPPQSAILAVGAGERRPIERNGELAFATMMSVTLSVDHRAVDGALGAQ 404
Query: 399 FLRKIKEGVEDPATIV 446
L K G+EDP +++
Sbjct: 405 LLAAFKAGIEDPMSLL 420
>UniRef50_Q73FZ4 Cluster: Pyruvate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase; n=9;
Rickettsiales|Rep: Pyruvate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase -
Wolbachia pipientis wMel
Length = 454
Score = 114 bits (274), Expect = 2e-24
Identities = 55/145 (37%), Positives = 84/145 (57%)
Frame = +3
Query: 12 ENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMD 191
+N+I+ +DIS+AVA GL+ P+++N I + L +AR+GKL EE
Sbjct: 303 DNKILRYSNIDISIAVALEDGLITPIVKNADKKGILSISKEVKDLVSRARSGKLKPEEFQ 362
Query: 192 GGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHR 371
GG FTISN G+FG + IINPPQS I+ + ++PI +N ++ I +M + L+ DHR
Sbjct: 363 GGGFTISNLGMFGIKAFSAIINPPQSCIMAVGASKKQPIVMNEKIEIAEIMTVTLSVDHR 422
Query: 372 LIDGREAVLFLRKIKEGVEDPATIV 446
+DG FL K +E+P ++
Sbjct: 423 AVDGALGAKFLNAFKHYIENPLVML 447
>UniRef50_Q47KD8 Cluster: Pyruvate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase; n=1;
Thermobifida fusca YX|Rep: Pyruvate dehydrogenase
complex, E2 component, dihydrolipoamide
acetyltransferase - Thermobifida fusca (strain YX)
Length = 431
Score = 114 bits (274), Expect = 2e-24
Identities = 51/145 (35%), Positives = 90/145 (62%)
Frame = +3
Query: 12 ENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMD 191
+++++ +++ +AVA GLVVPV+ + + +++ L EKAR GKL+ ++M
Sbjct: 286 DDKLLRHKRINVGIAVAVDTGLVVPVLHDADTLALSEVARRSRALVEKARDGKLSPQDMS 345
Query: 192 GGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHR 371
GGTF++SN G+FG + +INPP++AIL + + + P+ +G++V R + + L+ DHR
Sbjct: 346 GGTFSVSNLGMFGVESFSAVINPPEAAILAVGAMQQEPVVRDGEIVARHTIALELSVDHR 405
Query: 372 LIDGREAVLFLRKIKEGVEDPATIV 446
+DG FL+ + E +E P IV
Sbjct: 406 AVDGAVGAAFLKDLAEVLESPMRIV 430
>UniRef50_A6GB59 Cluster: Alpha keto acid dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase; n=1;
Plesiocystis pacifica SIR-1|Rep: Alpha keto acid
dehydrogenase complex, E2 component, dihydrolipoamide
acetyltransferase - Plesiocystis pacifica SIR-1
Length = 435
Score = 114 bits (274), Expect = 2e-24
Identities = 55/150 (36%), Positives = 95/150 (63%), Gaps = 2/150 (1%)
Frame = +3
Query: 12 ENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMD 191
+ I+ + I VA AT +GL+VPVI + ++ D+ + L E A+TG+L +E+
Sbjct: 286 QKRIVLKKRYSIGVAAATDQGLMVPVIHDADMLSLLDLAREVKRLGEGAKTGRLARDELT 345
Query: 192 GGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIAL-NGQVVIRPMMYIALTYDH 368
G TFTI++ G G ++ TPI+N P+ ILG+H I + P+ N ++VI +M ++++ DH
Sbjct: 346 GSTFTITSLGTIGGVLATPILNYPEVGILGVHAIRKVPVVNDNDEIVIGHIMNLSVSLDH 405
Query: 369 RLIDGREAVLFLRKIKEGVEDPA-TIVAGL 455
R++DG E FL++++ +EDP ++AG+
Sbjct: 406 RVVDGFEGASFLQEVRRYLEDPTLLLLAGI 435
>UniRef50_A3U7C0 Cluster: Lipoamide acyltransferase component of
branched-chain alpha-ketoacid dehydrogenase complex;
n=1; Croceibacter atlanticus HTCC2559|Rep: Lipoamide
acyltransferase component of branched-chain
alpha-ketoacid dehydrogenase complex - Croceibacter
atlanticus HTCC2559
Length = 480
Score = 114 bits (274), Expect = 2e-24
Identities = 57/146 (39%), Positives = 92/146 (63%), Gaps = 5/146 (3%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPKG-LVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIE 182
++ II ++++++ +A A P G L+VPV+++ ++ + +A AR KL +
Sbjct: 327 VDGRNIIVKEHINVGMATALPSGNLIVPVVKDADKKNLQELATDVNRMANLARENKLGGD 386
Query: 183 EMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIAL----NGQVVIRPMMYI 350
++ G TFTISN G FGS+MGTPIIN P++AIL I +RP + N + IR MMY+
Sbjct: 387 DIKGSTFTISNVGTFGSVMGTPIINQPEAAILATGIIKKRPEVITKDGNDTIEIRSMMYL 446
Query: 351 ALTYDHRLIDGREAVLFLRKIKEGVE 428
+L++DHR++DG FL+KI + +E
Sbjct: 447 SLSFDHRIVDGFLGGSFLKKIADNLE 472
>UniRef50_Q98PG1 Cluster: DIHYDROLIPOAMIDE ACETYLTRANSFERASE
COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX; n=1;
Mycoplasma pulmonis|Rep: DIHYDROLIPOAMIDE
ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE
COMPLEX - Mycoplasma pulmonis
Length = 315
Score = 113 bits (273), Expect = 3e-24
Identities = 59/139 (42%), Positives = 82/139 (58%)
Frame = +3
Query: 18 EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGG 197
E++Y D V++ VAV T GL+VPVI+N Q++ + I LA ART + +M G
Sbjct: 171 ELVYPDTVNLGVAVDTDHGLMVPVIKNAQSLNLVEFSQEIIRLANLARTKTIKPADMSGA 230
Query: 198 TFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLI 377
TFTI+N G GSL GTP+IN P+ AI G+ I ++ NG V +M+I + DHR I
Sbjct: 231 TFTITNYGSVGSLFGTPVINYPELAIAGVGAIVDKVYWKNGAAVPGKVMWITIAADHRWI 290
Query: 378 DGREAVLFLRKIKEGVEDP 434
DG F+ K+K +E P
Sbjct: 291 DGATMGKFISKVKSLLEQP 309
>UniRef50_A6C4P4 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex dihydrolipoamide acyltransferase (E2) component
and related enzyme; n=1; Planctomyces maris DSM
8797|Rep: Pyruvate/2-oxoglutarate dehydrogenase complex
dihydrolipoamide acyltransferase (E2) component and
related enzyme - Planctomyces maris DSM 8797
Length = 449
Score = 113 bits (273), Expect = 3e-24
Identities = 59/146 (40%), Positives = 89/146 (60%)
Frame = +3
Query: 9 EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEM 188
+ +EI+Y++Y++I VAV T GLVVPV+++V I + LA KAR +L + +M
Sbjct: 301 QTDEIVYKNYINIGVAVDTENGLVVPVVKDVDKKNIITIANEMNALAIKARDRRLEMNDM 360
Query: 189 DGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDH 368
GGTFTI+N G G TPI+N P+ AILGM LN V R M+ ++L+YDH
Sbjct: 361 QGGTFTITNLGGLGGTSFTPIVNYPEVAILGMSRSRHEFQLLNDSPVPRLMLPLSLSYDH 420
Query: 369 RLIDGREAVLFLRKIKEGVEDPATIV 446
R+I+G +A F+ ++ + DP ++
Sbjct: 421 RVINGADAARFIVRLSSLLSDPFNLL 446
>UniRef50_Q2S4D4 Cluster: 2-oxo acid dehydrogenases acyltransferase
(Catalytic domain) protein; n=1; Salinibacter ruber DSM
13855|Rep: 2-oxo acid dehydrogenases acyltransferase
(Catalytic domain) protein - Salinibacter ruber (strain
DSM 13855)
Length = 639
Score = 113 bits (272), Expect = 4e-24
Identities = 60/147 (40%), Positives = 90/147 (61%), Gaps = 6/147 (4%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATP-KGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIE 182
+E ++I+ + + +AVA KGL+ PVIRN + + + A +AE+AR +L +
Sbjct: 484 VEGDKIVIKHDFHVGIAVAIGNKGLLAPVIRNAGDYNVSGLARKAANVAERARNKELQPD 543
Query: 183 EMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPI-----ALNGQVVIRPMMY 347
E+ GGTFT++N G GSLMGTPIIN PQ IL I +RP+ L + +R MMY
Sbjct: 544 ELQGGTFTVTNIGSLGSLMGTPIINQPQVGILATGAIQKRPVVVENDGLGDAISVRHMMY 603
Query: 348 IALTYDHRLIDGREAVLFLRKIKEGVE 428
++L+YDHR+IDG FL+++ +E
Sbjct: 604 LSLSYDHRIIDGAMGSSFLQRVVTELE 630
>UniRef50_Q7D716 Cluster: 2-oxoisovalerate dehydrogenase E2
component, dihydrolipoamide acetyltransferase, putative;
n=13; Mycobacterium|Rep: 2-oxoisovalerate dehydrogenase
E2 component, dihydrolipoamide acetyltransferase,
putative - Mycobacterium tuberculosis
Length = 393
Score = 113 bits (272), Expect = 4e-24
Identities = 53/139 (38%), Positives = 83/139 (59%)
Frame = +3
Query: 39 VDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNG 218
V + AT +GL+VPV+ + Q+ ++ +A L AR G LT E+ G TFT+SN
Sbjct: 255 VHLGFGAATERGLLVPVVTDAQDKNTRELASRVAELITGAREGTLTPAELRGSTFTVSNF 314
Query: 219 GVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLIDGREAVL 398
G G G P+IN P++AILG+ I RP+ + G+VV RP M + +DHR++DG +
Sbjct: 315 GALGVDDGVPVINHPEAAILGLGAIKPRPVVVGGEVVARPTMTLTCVFDHRVVDGAQVAQ 374
Query: 399 FLRKIKEGVEDPATIVAGL 455
F+ ++++ +E P T + L
Sbjct: 375 FMCELRDLIESPETALLDL 393
>UniRef50_A3WJV9 Cluster: Apha keto acid dehydrogenase complex, E2
component; n=2; Alteromonadales|Rep: Apha keto acid
dehydrogenase complex, E2 component - Idiomarina baltica
OS145
Length = 515
Score = 113 bits (272), Expect = 4e-24
Identities = 59/147 (40%), Positives = 90/147 (61%), Gaps = 1/147 (0%)
Frame = +3
Query: 18 EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGG 197
E+ Y D +I +AV T GL+VP ++ VQN + D+ + L + AR GK+ +M GG
Sbjct: 368 EVTYFDDHNIGMAVDTKIGLLVPNVKQVQNKSIIDVANEVTRLTQAAREGKVPQADMKGG 427
Query: 198 TFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERP-IALNGQVVIRPMMYIALTYDHRL 374
T +ISN GV G + TPIIN P++AI+ + + E P NGQVV R MM ++ + DHR+
Sbjct: 428 TISISNIGVIGGTVATPIINKPEAAIVALGKVQELPRFDANGQVVARKMMTVSWSGDHRI 487
Query: 375 IDGREAVLFLRKIKEGVEDPATIVAGL 455
IDG F ++ +E +EDP +++ +
Sbjct: 488 IDGGTIARFNKRWQEFLEDPTSMLVNM 514
>UniRef50_A1ZE93 Cluster: Pyruvate dehydrogenase complex
dihydrolipoamide acetyltransferase; n=7; Bacteria|Rep:
Pyruvate dehydrogenase complex dihydrolipoamide
acetyltransferase - Microscilla marina ATCC 23134
Length = 547
Score = 113 bits (272), Expect = 4e-24
Identities = 55/142 (38%), Positives = 89/142 (62%), Gaps = 1/142 (0%)
Frame = +3
Query: 12 ENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMD 191
E++I Y +++ + +AVA GL VPV+R N+T++ + T L KA+ KL + +
Sbjct: 401 EDKIRYNNHIHVGMAVAVKDGLFVPVVRFADNLTFSQVATTTKDLVSKAKDKKLQPADWE 460
Query: 192 GGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALN-GQVVIRPMMYIALTYDH 368
G TF++SN G+FG T IINPP S IL + GI + P+ + GQ+ + +M + L+ DH
Sbjct: 461 GSTFSVSNLGMFGVEDFTAIINPPDSCILAVGGIKQTPVVNDEGQIEVGNIMKVTLSSDH 520
Query: 369 RLIDGREAVLFLRKIKEGVEDP 434
R++DG A FL+ +K+ +E+P
Sbjct: 521 RVVDGALAASFLKTLKQMIENP 542
>UniRef50_A0LSF1 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Acidothermus
cellulolyticus 11B|Rep: Catalytic domain of components
of various dehydrogenase complexes - Acidothermus
cellulolyticus (strain ATCC 43068 / 11B)
Length = 449
Score = 113 bits (272), Expect = 4e-24
Identities = 57/144 (39%), Positives = 87/144 (60%)
Frame = +3
Query: 18 EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGG 197
+++ ++ I VAVA P GL+VPVIR+ + +I LA +AR GKL +++ G
Sbjct: 306 KLLQHKHIHIGVAVAIPDGLIVPVIRDADTLGIREISQRTRDLATRARQGKLKPDDIGGS 365
Query: 198 TFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLI 377
TFTISN G+FG T +INPP++AIL + + E P+ +GQ+ + +M I L+ DHR +
Sbjct: 366 TFTISNLGMFGVDQFTAVINPPEAAILAVGAVREVPVVRDGQLAVGKVMTITLSIDHRAL 425
Query: 378 DGREAVLFLRKIKEGVEDPATIVA 449
DG A FL + +E+P +A
Sbjct: 426 DGATAAGFLADLVTLLENPLAALA 449
>UniRef50_Q6FDE9 Cluster: Dihydrolipoamide acetyltransferase; n=3;
Gammaproteobacteria|Rep: Dihydrolipoamide
acetyltransferase - Acinetobacter sp. (strain ADP1)
Length = 513
Score = 112 bits (269), Expect = 1e-23
Identities = 59/146 (40%), Positives = 86/146 (58%)
Frame = +3
Query: 9 EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEM 188
++ +I+ DISVAVA GL+ P+++ + A I T+ LA +A+TGKL +E
Sbjct: 367 QKQQILQFKDADISVAVAIENGLITPIVKAANQKSLATISSTMRDLATRAKTGKLQPDEF 426
Query: 189 DGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDH 368
GG+F+ISN G+ G IINPPQ AI+ + R + + +VIR MM + L+ DH
Sbjct: 427 QGGSFSISNLGMLGIKNFDAIINPPQGAIMALGRSEARAVVEHDLIVIRQMMTVTLSCDH 486
Query: 369 RLIDGREAVLFLRKIKEGVEDPATIV 446
R+IDG FL K+ VE+PA I+
Sbjct: 487 RVIDGALGAKFLASFKQFVENPALIL 512
>UniRef50_A4WK39 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=2; Pyrobaculum|Rep: Catalytic
domain of components of various dehydrogenase complexes
- Pyrobaculum arsenaticum (strain DSM 13514 / JCM 11321)
Length = 408
Score = 112 bits (269), Expect = 1e-23
Identities = 54/141 (38%), Positives = 87/141 (61%)
Frame = +3
Query: 9 EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEM 188
E EI+ + + + AV T +GL+V V+R+ + +I + LAE+AR GK +++E+
Sbjct: 260 ERGEIVVKRRIHLGFAVDTEQGLMVVVVRDADKKSVLEIARELNALAERARAGKASVDEV 319
Query: 189 DGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDH 368
G TFTI+N G G + G PIIN P++AI+ + I + P +NG VV R +M + + +DH
Sbjct: 320 RGSTFTITNIGAIGGVGGLPIINYPEAAIMALGKIRKIPRVVNGAVVPRDVMNVVVGFDH 379
Query: 369 RLIDGREAVLFLRKIKEGVED 431
R++DG F ++KE +ED
Sbjct: 380 RVVDGAYVARFTNRVKELLED 400
>UniRef50_Q19749 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex, mitochondrial precursor; n=6; Bilateria|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex, mitochondrial
precursor - Caenorhabditis elegans
Length = 507
Score = 112 bits (269), Expect = 1e-23
Identities = 63/140 (45%), Positives = 85/140 (60%), Gaps = 3/140 (2%)
Frame = +3
Query: 36 YVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISN 215
+VD+SVAV+TP GL+ P+I N A I I LA++AR GKL E GGTFT+SN
Sbjct: 368 HVDVSVAVSTPAGLITPIIFNAHAKGLATIASEIVELAQRAREGKLQPHEFQGGTFTVSN 427
Query: 216 GGVFGSLMG-TPIINPPQSAILGMHGIFER--PIALNGQVVIRPMMYIALTYDHRLIDGR 386
G+FGS+ T IINPPQS IL + G ++ P G I+ M + L+ DHR +DG
Sbjct: 428 LGMFGSVSDFTAIINPPQSCILAIGGASDKLVPDEAEGYKKIKTMK-VTLSCDHRTVDGA 486
Query: 387 EAVLFLRKIKEGVEDPATIV 446
++LR KE +E P T++
Sbjct: 487 VGAVWLRHFKEFLEKPHTML 506
>UniRef50_P09062 Cluster: Lipoamide acyltransferase component of
branched-chain alpha-keto acid dehydrogenase complex (EC
2.3.1.168) (Dihydrolipoyllysine-residue (2-
methylpropanoyl)transferase); n=27; Proteobacteria|Rep:
Lipoamide acyltransferase component of branched-chain
alpha-keto acid dehydrogenase complex (EC 2.3.1.168)
(Dihydrolipoyllysine-residue (2-
methylpropanoyl)transferase) - Pseudomonas putida
Length = 423
Score = 112 bits (269), Expect = 1e-23
Identities = 52/146 (35%), Positives = 94/146 (64%), Gaps = 1/146 (0%)
Frame = +3
Query: 9 EENEIIYRD-YVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEE 185
+E +II R V + +A GL+VPV+R+ + + I+ LA AR K + EE
Sbjct: 275 DEAQIITRHGAVHVGIATQGDNGLMVPVLRHAEAGSLWANAGEISRLANAARNNKASREE 334
Query: 186 MDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYD 365
+ G T T+++ G G ++ TP++N P+ AI+G++ + ERP+ ++GQ+V+R MM ++ ++D
Sbjct: 335 LSGSTITLTSLGALGGIVSTPVVNTPEVAIVGVNRMVERPVVIDGQIVVRKMMNLSSSFD 394
Query: 366 HRLIDGREAVLFLRKIKEGVEDPATI 443
HR++DG +A LF++ ++ +E PA +
Sbjct: 395 HRVVDGMDAALFIQAVRGLLEQPACL 420
>UniRef50_Q4L6L6 Cluster: Branched-chain alpha-keto acid
dehydrogenase E2; n=3; Staphylococcus|Rep:
Branched-chain alpha-keto acid dehydrogenase E2 -
Staphylococcus haemolyticus (strain JCSC1435)
Length = 442
Score = 111 bits (268), Expect = 1e-23
Identities = 55/137 (40%), Positives = 86/137 (62%)
Frame = +3
Query: 18 EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGG 197
EII ++IS+AVA L VPVI++ + I I LA KAR +L+ E+M GG
Sbjct: 296 EIILHKDINISIAVADEDKLYVPVIKHADEKSIKGIAREINELALKARNKQLSQEDMSGG 355
Query: 198 TFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLI 377
TFT++N G FGS+ IIN PQ+AIL + I ++P+ ++ + IR M+ + ++ DHR++
Sbjct: 356 TFTVNNTGTFGSVSSMGIINHPQAAILQVESIVKKPVVIDDMIAIRSMVNLCISIDHRIL 415
Query: 378 DGREAVLFLRKIKEGVE 428
DG + F+ ++KE +E
Sbjct: 416 DGVQTGRFMSQVKERIE 432
>UniRef50_A3HTS0 Cluster: 2-oxo acid dehydrogenases acyltransferase
(Catalytic domain) protein; n=2; Bacteroidetes|Rep:
2-oxo acid dehydrogenases acyltransferase (Catalytic
domain) protein - Algoriphagus sp. PR1
Length = 432
Score = 111 bits (268), Expect = 1e-23
Identities = 55/147 (37%), Positives = 94/147 (63%), Gaps = 5/147 (3%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPKG-LVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIE 182
I+ ++II + ++I +AVA P G L+VPVIR + I + LA +AR KL +
Sbjct: 279 IDGDKIIKKKDINIGMAVALPSGNLIVPVIRKADQLNLVGISKQVNDLANRARNNKLNAD 338
Query: 183 EMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIAL---NGQVV-IRPMMYI 350
++ GGT+T+SN G FG++MGTPII PQ AI+ + I ++P + G V+ +R M++
Sbjct: 339 DLSGGTYTVSNVGSFGNVMGTPIIMQPQVAIMAVGAIVKKPAVVETPTGDVIAVRHKMFL 398
Query: 351 ALTYDHRLIDGREAVLFLRKIKEGVED 431
+ +YDHR++DG +F++++ + +E+
Sbjct: 399 SHSYDHRVVDGSLGGMFVKRVADYLEE 425
>UniRef50_Q8CX89 Cluster: Pyruvate dehydrogenase E2; n=4;
Bacillaceae|Rep: Pyruvate dehydrogenase E2 -
Oceanobacillus iheyensis
Length = 420
Score = 111 bits (267), Expect = 2e-23
Identities = 57/150 (38%), Positives = 88/150 (58%), Gaps = 1/150 (0%)
Frame = +3
Query: 9 EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEM 188
E+ EI + + +A T +GL+VPVI++ + I + L +KA+ L+++EM
Sbjct: 270 EKEEIRLEKGIHMGIATDTEEGLIVPVIQSADIKSIRTIHREMKELMKKAKENTLSLKEM 329
Query: 189 DGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIAL-NGQVVIRPMMYIALTYD 365
G TFTISN G GS+ TPIIN P+ A++ H + P+ N ++VIR MM + LT+D
Sbjct: 330 TGSTFTISNVGPMGSIGATPIINYPEVALMAFHKTKKAPVVNDNDEIVIRSMMNVTLTFD 389
Query: 366 HRLIDGREAVLFLRKIKEGVEDPATIVAGL 455
HR+ DG A+ F K K +E+P ++ L
Sbjct: 390 HRVTDGGNAIAFTNKFKALIENPRLLLIEL 419
>UniRef50_Q74AE1 Cluster: Dehydrogenase complex E2 component,
dihydrolipamide acetyltransferase; n=4; Geobacter|Rep:
Dehydrogenase complex E2 component, dihydrolipamide
acetyltransferase - Geobacter sulfurreducens
Length = 418
Score = 111 bits (267), Expect = 2e-23
Identities = 53/136 (38%), Positives = 87/136 (63%)
Frame = +3
Query: 39 VDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNG 218
V+I AVA +GL VPV++ Q++ +I L LAE+AR+G +T EE+ GGTF++SN
Sbjct: 282 VNIGFAVAMEEGLQVPVVKGCQSLALKEIALQTVRLAERARSGAITQEEISGGTFSVSNL 341
Query: 219 GVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLIDGREAVL 398
G++G +I PPQ+AIL + + +RP+ +GQ+ + M L+ DHR++DG A
Sbjct: 342 GMYGIDEFAAVIMPPQAAILAVGAVADRPVVRDGQLAVARTMRATLSCDHRVVDGAYAAQ 401
Query: 399 FLRKIKEGVEDPATIV 446
FL +++ +E+P ++
Sbjct: 402 FLGELRRVLENPVLML 417
>UniRef50_Q1IIF0 Cluster: Dihydrolipoamide S-succinyltransferase;
n=2; Acidobacteria|Rep: Dihydrolipoamide
S-succinyltransferase - Acidobacteria bacterium (strain
Ellin345)
Length = 555
Score = 111 bits (267), Expect = 2e-23
Identities = 54/147 (36%), Positives = 91/147 (61%), Gaps = 5/147 (3%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEE 185
+E I Y+ +++ +AVA GL+VPV++ +++ ++ I L E+AR KL E+
Sbjct: 403 VEGENIHYKKDINLGIAVALDWGLIVPVVKQADGLSFVGLQRAITDLGERARAKKLKPED 462
Query: 186 MDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIAL-----NGQVVIRPMMYI 350
+ GGTFTI+N G+FG+ G PII+ PQ AILG+ I + P+ + N + IR +I
Sbjct: 463 VQGGTFTITNPGIFGAKFGMPIISQPQLAILGIGAITKVPMVVTDKDGNDSIAIRSRCHI 522
Query: 351 ALTYDHRLIDGREAVLFLRKIKEGVED 431
++ YDHR+IDG A F+ +++ +++
Sbjct: 523 SIGYDHRVIDGAVADQFMVVVRDYLQN 549
>UniRef50_Q0RVL0 Cluster: Dihydrolipoyllysine-residue
succinyltransferase; n=1; Rhodococcus sp. RHA1|Rep:
Dihydrolipoyllysine-residue succinyltransferase -
Rhodococcus sp. (strain RHA1)
Length = 422
Score = 111 bits (267), Expect = 2e-23
Identities = 54/149 (36%), Positives = 89/149 (59%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEE 185
++ + II D+V + +AV+ P GL+VPV+R+ ++ I A AR K+T +
Sbjct: 274 VQADRIIEHDHVHLGMAVSVPDGLIVPVVRDADQLSLRAIHQRSEEAALAARERKVTAAD 333
Query: 186 MDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYD 365
+ GGTFT++N G +GS GTP++N PQ AIL I +RP+ +G+V +++++LT D
Sbjct: 334 LTGGTFTVTNIGSYGSHFGTPVLNLPQVAILATGAILDRPVVRDGEVRAGKVVHLSLTVD 393
Query: 366 HRLIDGREAVLFLRKIKEGVEDPATIVAG 452
HR+IDG A F + + +P ++ G
Sbjct: 394 HRIIDGELAGRFHNTMAALLAEPDRLLVG 422
>UniRef50_A6TMP1 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Alkaliphilus
metalliredigens QYMF|Rep: Catalytic domain of components
of various dehydrogenase complexes - Alkaliphilus
metalliredigens QYMF
Length = 438
Score = 111 bits (267), Expect = 2e-23
Identities = 55/142 (38%), Positives = 91/142 (64%), Gaps = 1/142 (0%)
Frame = +3
Query: 9 EENE-IIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEE 185
EEN+ +I + Y +I +AV TP+GL VPVI++V + L++ A+ L + +
Sbjct: 290 EENQMLILKKYYNIGIAVDTPEGLTVPVIKDVDQKGLMSLMEESVRLSQSAKDKSLKLNQ 349
Query: 186 MDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYD 365
+ G TFTI+N G G G PIIN P+ AI+G+ I ++P+ ++ +VVIR MM ++L++D
Sbjct: 350 LKGSTFTITNLGSLGVKSGMPIINYPEVAIIGIGQIEQKPVVVDNEVVIRWMMPLSLSFD 409
Query: 366 HRLIDGREAVLFLRKIKEGVED 431
HR++DG + FL + K+ ++D
Sbjct: 410 HRVLDGGDVGRFLNQFKKYIKD 431
>UniRef50_A0K281 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=2; Arthrobacter|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Arthrobacter sp. (strain FB24)
Length = 527
Score = 111 bits (267), Expect = 2e-23
Identities = 53/143 (37%), Positives = 90/143 (62%)
Frame = +3
Query: 18 EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGG 197
EI + ++++ +A ATP+GL+VP I+N Q+++ ++ L + LA AR GK EM GG
Sbjct: 384 EIHVKHFMNLGIAAATPRGLMVPNIKNAQDLSLKELALALNDLATTARAGKTRPAEMQGG 443
Query: 198 TFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLI 377
T T++N G G GTPIINP + AI+ I ++P L+G+V+ R + + ++DHR++
Sbjct: 444 TLTVTNIGALGIDTGTPIINPGEVAIVAFGTIKQKPWVLDGEVIPRWITTLGGSFDHRVV 503
Query: 378 DGREAVLFLRKIKEGVEDPATIV 446
DG + F+ + +E+PA ++
Sbjct: 504 DGDLSARFMADVAAILEEPALLL 526
>UniRef50_Q5Z123 Cluster: Putative branched-chain alpha-keto acid
dehydrogenase component; n=1; Nocardia farcinica|Rep:
Putative branched-chain alpha-keto acid dehydrogenase
component - Nocardia farcinica
Length = 510
Score = 111 bits (266), Expect = 2e-23
Identities = 54/149 (36%), Positives = 88/149 (59%)
Frame = +3
Query: 9 EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEM 188
E +I+ + YV + +A AT +GL+VP ++ ++ ++ I E AR G T ++
Sbjct: 362 ERQQIVTKRYVHLGIAAATDRGLLVPSVKEAHRLSLRELCAEIGRTIEAARAGTATPADL 421
Query: 189 DGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDH 368
GGTFTI+N GVFG G P++NP ++AIL + I RP + ++ +R + + L++DH
Sbjct: 422 TGGTFTITNVGVFGVDSGVPLVNPGEAAILCLGAIGRRPWVVADELAVRWVTTLGLSFDH 481
Query: 369 RLIDGREAVLFLRKIKEGVEDPATIVAGL 455
RLIDG A FL + + DP T+++ L
Sbjct: 482 RLIDGELAARFLATVAGLLTDPLTLLSRL 510
>UniRef50_Q1VYW1 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvatedehydrogenase
complex; n=11; Bacteroidetes|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvatedehydrogenase complex - Psychroflexus torquis
ATCC 700755
Length = 572
Score = 111 bits (266), Expect = 2e-23
Identities = 55/139 (39%), Positives = 82/139 (58%)
Frame = +3
Query: 33 DYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTIS 212
+++ + VAVA +GL+VPV+ + I + LA KA+ KL EM+G TFT+S
Sbjct: 434 NHIHVGVAVAVDEGLLVPVLEFADQQSLTQIGSNVKNLAGKAKNKKLQPNEMEGSTFTVS 493
Query: 213 NGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLIDGREA 392
N G+FG T IIN P SAIL + I E+P+ G++V+ M + L DHR +DG
Sbjct: 494 NLGMFGITEFTSIINQPNSAILSVGTIVEKPVVKKGEIVVGHTMILTLACDHRTVDGATG 553
Query: 393 VLFLRKIKEGVEDPATIVA 449
FL+ +K +E+P T++A
Sbjct: 554 AKFLQTLKIYLENPVTMLA 572
>UniRef50_A2TU26 Cluster: Lipoamide acyltransferase component of
branched-chain alpha-ketoacid dehydrogenase complex;
n=4; Bacteroidetes|Rep: Lipoamide acyltransferase
component of branched-chain alpha-ketoacid dehydrogenase
complex - Dokdonia donghaensis MED134
Length = 439
Score = 111 bits (266), Expect = 2e-23
Identities = 60/146 (41%), Positives = 90/146 (61%), Gaps = 5/146 (3%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPKG-LVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIE 182
++ II ++ ++I +A A P G L+VPV++N +I + L+ AR KL +
Sbjct: 286 VDGKNIIVKEDINIGMATALPSGNLIVPVVKNANQRNLVEIAAEVNRLSSLARENKLGGD 345
Query: 183 EMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIAL---NGQVV-IRPMMYI 350
++ G TFTISN G FGS+MGTPIIN P++AIL I +R + G + IR MMY+
Sbjct: 346 DVKGSTFTISNVGTFGSVMGTPIINQPEAAILATGIIKKRAEVMERPEGDTIEIRQMMYL 405
Query: 351 ALTYDHRLIDGREAVLFLRKIKEGVE 428
+L++DHR++DG FLRKI + +E
Sbjct: 406 SLSFDHRIVDGYLGGSFLRKIADHLE 431
>UniRef50_Q8AB01 Cluster: Lipoamide acyltransferase component of
branched-chain alpha-keto acid dehydrogenase complex;
n=8; Bacteroidetes|Rep: Lipoamide acyltransferase
component of branched-chain alpha-keto acid
dehydrogenase complex - Bacteroides thetaiotaomicron
Length = 456
Score = 110 bits (265), Expect = 3e-23
Identities = 57/147 (38%), Positives = 92/147 (62%), Gaps = 5/147 (3%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPKG-LVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIE 182
++ I+++ +++I +AV+ G L+VPV+ + ++ + + I LA KAR KL +
Sbjct: 307 VDGYNILFKKHINIGIAVSLNDGNLIVPVVHDADHLNLNGLAVAIDSLALKARDNKLMPD 366
Query: 183 EMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIAL----NGQVVIRPMMYI 350
++DGGTFTI+N G F SL GTP+IN PQ AILG+ I ++P + + IR MY+
Sbjct: 367 DIDGGTFTITNFGTFKSLFGTPVINQPQVAILGVGYIEKKPAVIETPEGDTIAIRHKMYL 426
Query: 351 ALTYDHRLIDGREAVLFLRKIKEGVED 431
+L+YDHR++DG FL I + +E+
Sbjct: 427 SLSYDHRVVDGMLGGNFLHFIADYLEN 453
>UniRef50_Q1YS54 Cluster: Dihydrolipoamide acetyltransferase; n=1;
gamma proteobacterium HTCC2207|Rep: Dihydrolipoamide
acetyltransferase - gamma proteobacterium HTCC2207
Length = 496
Score = 110 bits (265), Expect = 3e-23
Identities = 55/143 (38%), Positives = 85/143 (59%)
Frame = +3
Query: 18 EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGG 197
++ Y DISVAVA GL+ P++ + + +I T LA +A+ G+L EE GG
Sbjct: 353 QLSYFSNADISVAVAIDDGLITPIVSDANHKGLVEISNTTRDLATRAKLGRLKPEEFQGG 412
Query: 198 TFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLI 377
+F ISN G++G IINPPQ AIL + +RP+ +G++ + +M + L+ DHR+I
Sbjct: 413 SFCISNLGMYGIKQFDAIINPPQGAILAVGAGEQRPVVKDGELAVATVMSLTLSSDHRII 472
Query: 378 DGREAVLFLRKIKEGVEDPATIV 446
DG A F+ +K +E PAT++
Sbjct: 473 DGAVAAQFMSVLKGYLEQPATML 495
>UniRef50_Q03Y73 Cluster: Acetoin/pyruvate dehydrogenase complex, E2
component, dihydrolipoamide succinyltransferase; n=2;
Lactobacillales|Rep: Acetoin/pyruvate dehydrogenase
complex, E2 component, dihydrolipoamide
succinyltransferase - Leuconostoc mesenteroides subsp.
mesenteroides (strain ATCC 8293 /NCDO 523)
Length = 431
Score = 110 bits (265), Expect = 3e-23
Identities = 61/145 (42%), Positives = 83/145 (57%), Gaps = 1/145 (0%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEE 185
++ EI+Y D V++ +AV P GL VPVI+N + I I LAE R G +T +
Sbjct: 281 MKAQEIVYHDDVNMGIAVDAPTGLFVPVIKNADRKSIFTIAQEITDLAEAVRDGSITPAQ 340
Query: 186 MDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIAL-NGQVVIRPMMYIALTY 362
M GGT TISN G TPIIN + AILG+ I + PI +G++ + M ++LTY
Sbjct: 341 MQGGTITISNLGSARGTWFTPIINGKEVAILGLGSILKEPIVNDDGELAVGQNMKLSLTY 400
Query: 363 DHRLIDGREAVLFLRKIKEGVEDPA 437
DHRLIDG L +K+ + DPA
Sbjct: 401 DHRLIDGMLGQSALNYLKQLLSDPA 425
>UniRef50_A1SQ65 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Nocardioides sp.
JS614|Rep: Catalytic domain of components of various
dehydrogenase complexes - Nocardioides sp. (strain
BAA-499 / JS614)
Length = 427
Score = 110 bits (265), Expect = 3e-23
Identities = 55/137 (40%), Positives = 87/137 (63%)
Frame = +3
Query: 39 VDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNG 218
VD++VAVAT +GLV PV+R+V ++T + + LA +AR G+L +E++GGT +++N
Sbjct: 291 VDVAVAVATDRGLVTPVLRDVTSLTVTAVAAKVQDLAARAREGRLKQDELEGGTISVTNL 350
Query: 219 GVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLIDGREAVL 398
G++G IINPP +AIL + + E P+ +G VV ++ + L+ DHR +DG A
Sbjct: 351 GMYGVEEFAAIINPPHAAILAVGAVREEPVVEDGAVVPGKVLTVTLSVDHRPVDGVVAAR 410
Query: 399 FLRKIKEGVEDPATIVA 449
+L + VE PA I+A
Sbjct: 411 WLAAFVDLVEHPARILA 427
>UniRef50_A1R9E2 Cluster: Pyruvate dehydrogenase E2; n=2;
Actinomycetales|Rep: Pyruvate dehydrogenase E2 -
Arthrobacter aurescens (strain TC1)
Length = 493
Score = 110 bits (265), Expect = 3e-23
Identities = 53/146 (36%), Positives = 87/146 (59%)
Frame = +3
Query: 18 EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGG 197
EI+ + +++ A T +GLVVP +RN ++ +++ I L AR GK T E+ G
Sbjct: 348 EIVGFEGINLGFAAQTDRGLVVPSVRNAHELSARELDAEIRRLTAVARDGKATPTELGSG 407
Query: 198 TFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLI 377
TFT++N GVFG IIN P+ A+LG+ I ++P +NG++ +R + + L +DHR+
Sbjct: 408 TFTLNNYGVFGVDGSAAIINYPEVAMLGVGRIIDKPWVVNGELAVRKVTELTLAFDHRVC 467
Query: 378 DGREAVLFLRKIKEGVEDPATIVAGL 455
DG A FLR + + +E+P +A +
Sbjct: 468 DGETAAGFLRYVADAIENPGGALADM 493
>UniRef50_Q6A613 Cluster: Dihydrolipoamide acetyltransferase
component of pyruvate dehydrogenase complex; n=1;
Propionibacterium acnes|Rep: Dihydrolipoamide
acetyltransferase component of pyruvate dehydrogenase
complex - Propionibacterium acnes
Length = 469
Score = 110 bits (264), Expect = 4e-23
Identities = 55/146 (37%), Positives = 92/146 (63%), Gaps = 4/146 (2%)
Frame = +3
Query: 15 NEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDG 194
++I++RD++++ +A ATP+GL+VPV+R+ Q+M ++ I + A+ KL +
Sbjct: 320 DQIVFRDHINLGIAAATPRGLMVPVVRDAQDMAMLELATEITRIVAIAKEDKLQPPDYAD 379
Query: 195 GTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIAL----NGQVVIRPMMYIALTY 362
GTF+I+N GVFG GTP++N +SAIL + + RP + + +VV R + ++L +
Sbjct: 380 GTFSITNVGVFGLDAGTPVVNRTESAILVLGALARRPWVVGTGDDERVVPRWVTTMSLGF 439
Query: 363 DHRLIDGREAVLFLRKIKEGVEDPAT 440
DHRLIDG + FL + E + DPA+
Sbjct: 440 DHRLIDGEQGSTFLHDVAEILSDPAS 465
>UniRef50_Q2GCH9 Cluster: Pyruvate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase; n=1;
Neorickettsia sennetsu str. Miyayama|Rep: Pyruvate
dehydrogenase complex, E2 component, dihydrolipoamide
acetyltransferase - Neorickettsia sennetsu (strain
Miyayama)
Length = 403
Score = 110 bits (264), Expect = 4e-23
Identities = 55/146 (37%), Positives = 89/146 (60%), Gaps = 1/146 (0%)
Frame = +3
Query: 12 ENEIIYRDY-VDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEM 188
E E I ++ +DISVAVA P GL+ P++ + ++ + I + L +KA+ G+L E
Sbjct: 258 EGEFIRQNQTIDISVAVAIPDGLITPIVFSADKLSLSSISDEVRELVDKAKAGRLQPREF 317
Query: 189 DGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDH 368
GG+FT+SN G++G T IINPPQ+AIL + + P VV+ ++ + L+ DH
Sbjct: 318 QGGSFTVSNLGMYGIDEFTAIINPPQAAILAVGAARKVPTVSADAVVVSDVVTLTLSCDH 377
Query: 369 RLIDGREAVLFLRKIKEGVEDPATIV 446
R+IDG A F++ +K+ +EDP ++
Sbjct: 378 RVIDGALAARFMQSLKKAIEDPVIML 403
>UniRef50_Q14Q97 Cluster: Putative uncharacterized protein; n=1;
Spiroplasma citri|Rep: Putative uncharacterized protein -
Spiroplasma citri
Length = 992
Score = 110 bits (264), Expect = 4e-23
Identities = 57/144 (39%), Positives = 89/144 (61%), Gaps = 1/144 (0%)
Frame = +3
Query: 15 NEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDG 194
N+I+ ++ I +A T +GLV+PVI+ + M+ I + I E+ R G+L E+ G
Sbjct: 846 NQIVIKNSQHIGLATETSEGLVIPVIKFAERMSLKQIAINIQETIERLRQGELYDYELKG 905
Query: 195 GTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNG-QVVIRPMMYIALTYDHR 371
T TI+N G+ G++ TP I P SA++G+ I +PI + G ++VIR +M +ALT D R
Sbjct: 906 STITIANYGMVGAVNATPTIFYPNSAVIGVGRIVRKPIVIKGDKLVIRSIMNLALTIDQR 965
Query: 372 LIDGREAVLFLRKIKEGVEDPATI 443
+ID EA +FL ++KE +E P I
Sbjct: 966 IIDAAEAGIFLTRVKEILESPELI 989
>UniRef50_A6EAZ4 Cluster: Dihydrolipoyllysine-residue
acetyltransferase; n=2; Bacteroidetes|Rep:
Dihydrolipoyllysine-residue acetyltransferase -
Pedobacter sp. BAL39
Length = 549
Score = 110 bits (264), Expect = 4e-23
Identities = 56/144 (38%), Positives = 86/144 (59%)
Frame = +3
Query: 15 NEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDG 194
++I Y ++V+I VAVA GL+VPV+R + + I + A++A+ KL + +G
Sbjct: 405 DKIRYNEHVNIGVAVAVEDGLLVPVVRFADGKSLSHISAEVKDFAQRAKAKKLQPADWEG 464
Query: 195 GTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRL 374
TFTISN G+FG T IINPP + IL + GI + P+ NG VV +M + L+ DHR+
Sbjct: 465 STFTISNLGMFGIDEFTAIINPPDACILAIGGISQVPVVKNGAVVPGNVMKVTLSCDHRV 524
Query: 375 IDGREAVLFLRKIKEGVEDPATIV 446
+DG FL+ K +E+P ++
Sbjct: 525 VDGATGSAFLQTFKSLLEEPVRLL 548
>UniRef50_Q5UWH1 Cluster: Dihydrolipoamide S-acetyltransferase
component of pyruvate dehydrogenase complex E2; n=3;
Halobacteriaceae|Rep: Dihydrolipoamide
S-acetyltransferase component of pyruvate dehydrogenase
complex E2 - Haloarcula marismortui (Halobacterium
marismortui)
Length = 540
Score = 110 bits (264), Expect = 4e-23
Identities = 59/143 (41%), Positives = 88/143 (61%), Gaps = 4/143 (2%)
Frame = +3
Query: 18 EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGG 197
EI+ + Y +I VA AT GL+VPV+ NV ++ +KAR L+ EEM GG
Sbjct: 392 EIVEKQYYNIGVATATDDGLLVPVVENVDAKGLLEVASETNEKTQKARERSLSPEEMRGG 451
Query: 198 TFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERP--IALNGQVVIRP--MMYIALTYD 365
TFTISN G G GTPIIN P+SAIL + I ++P + +G+ I P +M ++L++D
Sbjct: 452 TFTISNIGGIGGEYGTPIINQPESAILALGEIKKKPRVVEADGEETIEPRHIMTLSLSFD 511
Query: 366 HRLIDGREAVLFLRKIKEGVEDP 434
HR++DG +A F I++ +++P
Sbjct: 512 HRVLDGADAAQFTNSIQKYLQNP 534
>UniRef50_Q6ABX9 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=5; Actinomycetales|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex - Leifsonia xyli
subsp. xyli
Length = 452
Score = 109 bits (263), Expect = 5e-23
Identities = 54/145 (37%), Positives = 88/145 (60%)
Frame = +3
Query: 12 ENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMD 191
+ EII R YV++ +A ATP+GL+VP ++ Q M+ ++ + L AR GK +M
Sbjct: 307 DEEIIVRHYVNLGIAAATPRGLIVPNVKEAQGMSLLELAGALEELTLTAREGKTQPADMA 366
Query: 192 GGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHR 371
GT TI+N GVFG GTPI+NP + I+ + I ++P ++G+V R + + ++DHR
Sbjct: 367 NGTITITNIGVFGMDTGTPILNPGEVGIVALGTIKQKPWVVDGEVRPRFVTTLGGSFDHR 426
Query: 372 LIDGREAVLFLRKIKEGVEDPATIV 446
++DG A FL + +E+PA ++
Sbjct: 427 VVDGDVASRFLADVASIIEEPALLL 451
>UniRef50_Q2S152 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvatedehydrogenase
complex; n=1; Salinibacter ruber DSM 13855|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvatedehydrogenase complex - Salinibacter ruber
(strain DSM 13855)
Length = 465
Score = 109 bits (262), Expect = 7e-23
Identities = 58/146 (39%), Positives = 85/146 (58%)
Frame = +3
Query: 9 EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEM 188
+E EI + V I +AVA +GL+ PVIR+ +++ LAE+AR L EE
Sbjct: 319 DEGEIHKHNRVHIGIAVAIDEGLITPVIRDADRKGLSELARETRALAERARDRDLEPEEF 378
Query: 189 DGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDH 368
+G TFT SN G+FG T IINPP SAIL + I + P+ +G+VV M + L+ DH
Sbjct: 379 EGATFTTSNLGMFGIEEFTAIINPPNSAILAIGEIRDTPVVEDGEVVPGKRMKVTLSCDH 438
Query: 369 RLIDGREAVLFLRKIKEGVEDPATIV 446
R++DG + FL +K +E+P ++
Sbjct: 439 RVVDGAKGAHFLDTVKSYLEEPMNLL 464
>UniRef50_Q8ZUR6 Cluster: Pyruvate dehydrogenase E2; n=1;
Pyrobaculum aerophilum|Rep: Pyruvate dehydrogenase E2 -
Pyrobaculum aerophilum
Length = 383
Score = 109 bits (262), Expect = 7e-23
Identities = 52/142 (36%), Positives = 89/142 (62%)
Frame = +3
Query: 9 EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEM 188
E+N I+ + V++ + V T +GLVV V++N ++ I LA+KAR GKL ++++
Sbjct: 237 EKNAIVVKKEVNLGIGVDTEQGLVVVVVKNADKKGLLEMAKEINELAQKAREGKLELQDV 296
Query: 189 DGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDH 368
G TFTISN G G L G I+N P++ IL + ++P A+ ++ IR + +A+++DH
Sbjct: 297 RGSTFTISNIGAVGGLGGLSILNYPEAGILAVGQARKKPWAVGDRIEIRDIALLAVSFDH 356
Query: 369 RLIDGREAVLFLRKIKEGVEDP 434
R++DG F+ ++KE +E+P
Sbjct: 357 RVVDGAYVARFMNRVKELLENP 378
>UniRef50_Q2J8A0 Cluster: Dehydrogenase subunit; n=9; Actinobacteria
(class)|Rep: Dehydrogenase subunit - Frankia sp. (strain
CcI3)
Length = 487
Score = 108 bits (260), Expect = 1e-22
Identities = 54/149 (36%), Positives = 90/149 (60%), Gaps = 5/149 (3%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEE 185
+E + Y ++ +AV + +GLVVPVI N ++ + I LA + R +++ +E
Sbjct: 332 VEAGTVTYHGEENLGIAVDSERGLVVPVIHNAGDLNLIGLARKIDDLASRTRANRISPDE 391
Query: 186 MDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALN----GQVV-IRPMMYI 350
+ GGTFT++N G G+L TPIIN PQ ILG + ++P ++ G+++ +R +Y+
Sbjct: 392 LGGGTFTLTNTGSRGALFDTPIINQPQVGILGTGIVTKKPAVVDDPELGEIIAVRSTVYL 451
Query: 351 ALTYDHRLIDGREAVLFLRKIKEGVEDPA 437
+LTYDHR++DG +A FL K +E+ A
Sbjct: 452 SLTYDHRIVDGADAARFLAFTKHRLENGA 480
>UniRef50_A1ZHD0 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=2; Bacteroidetes|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Microscilla marina ATCC 23134
Length = 454
Score = 108 bits (260), Expect = 1e-22
Identities = 58/146 (39%), Positives = 89/146 (60%), Gaps = 5/146 (3%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPKG-LVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIE 182
IE II + ++I +A A P G L+VPVI+N M + + LA +AR KL +
Sbjct: 301 IEGENIIVKKDINIGMATALPSGNLIVPVIKNADQMNLLGLAKRVNDLANRARNNKLNPD 360
Query: 183 EMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIAL---NGQVV-IRPMMYI 350
E+ GGT+T+SN G FG+ MGTPI+ PQ IL + I ++P+ + G V+ IR MM++
Sbjct: 361 ELSGGTYTMSNIGGFGNEMGTPILVQPQVGILAIGAIKKKPVVIETPTGDVIGIRHMMFM 420
Query: 351 ALTYDHRLIDGREAVLFLRKIKEGVE 428
+ YDHR++DG F+R++ + +E
Sbjct: 421 SHAYDHRIVDGALGGGFVRRVADYLE 446
>UniRef50_Q1GTH9 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=5; Alphaproteobacteria|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Sphingopyxis alaskensis (Sphingomonas
alaskensis)
Length = 441
Score = 107 bits (258), Expect = 2e-22
Identities = 52/137 (37%), Positives = 85/137 (62%)
Frame = +3
Query: 39 VDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNG 218
V + +A T GL+VPVIR+ Q+ + I LAE ARTGK+ +EE+ GGT T+++
Sbjct: 304 VHLGMATQTDAGLMVPVIRDAQDKNVWQLASEITRLAEAARTGKVKVEELTGGTLTVTSL 363
Query: 219 GVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLIDGREAVL 398
G G + TP+IN P+ AI+G + I ERPI + +M ++++ DHR++DG +A
Sbjct: 364 GPLGGIATTPVINRPEVAIIGPNKIVERPIFDGDDIRRAKLMNLSISCDHRVVDGWDAAS 423
Query: 399 FLRKIKEGVEDPATIVA 449
+++ +K+ +E P + A
Sbjct: 424 YVQALKKLIETPVLLFA 440
>UniRef50_A0YCP9 Cluster: Pyruvate dehydrogenase complex
dihydrolipoamide acetyltransferase; n=2; unclassified
Gammaproteobacteria|Rep: Pyruvate dehydrogenase complex
dihydrolipoamide acetyltransferase - marine gamma
proteobacterium HTCC2143
Length = 568
Score = 107 bits (258), Expect = 2e-22
Identities = 54/130 (41%), Positives = 84/130 (64%)
Frame = +3
Query: 15 NEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDG 194
++++Y+ YV+I +AV TP GLVVPVIR+V + ++ +A+KA+ KL I++M G
Sbjct: 424 HQLVYKQYVNIGIAVDTPLGLVVPVIRDVDKKSIWELAAETVEMAQKAKDRKLKIDDMQG 483
Query: 195 GTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRL 374
G FT+S+ G G TPIIN P+ AILG+ + +P+ + V M+ ++L+YDHR
Sbjct: 484 GCFTVSSLGNIGGQGFTPIINVPEVAILGVSKLSVKPLWNGTEFVPAKMLPLSLSYDHRA 543
Query: 375 IDGREAVLFL 404
I+G +A FL
Sbjct: 544 INGGDAGRFL 553
>UniRef50_Q2JGZ2 Cluster: Dehydrogenase subunit; n=1; Frankia sp.
CcI3|Rep: Dehydrogenase subunit - Frankia sp. (strain
CcI3)
Length = 524
Score = 107 bits (257), Expect = 3e-22
Identities = 54/144 (37%), Positives = 84/144 (58%)
Frame = +3
Query: 18 EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGG 197
EI D V++ +AVA P+GLVVP I + + + +AGL AR +L+ ++ GG
Sbjct: 379 EIHVYDRVNLGIAVAGPRGLVVPTIPDAGRLDVVGLAHALAGLTTAARADRLSPADLRGG 438
Query: 198 TFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLI 377
T TI+N GV G +GTPI+NP ++AIL + I P GQ+ +R ++ +AL++DHR++
Sbjct: 439 TITITNVGVLGVDIGTPILNPGEAAILALGSIRPMPWVHEGQLTVRTVVQLALSFDHRIV 498
Query: 378 DGREAVLFLRKIKEGVEDPATIVA 449
DG L + + DP +A
Sbjct: 499 DGALGSAVLADVGAVITDPTVALA 522
>UniRef50_Q9RPS3 Cluster: Dihydrolipoamide acyltransferase; n=3;
Lactobacillales|Rep: Dihydrolipoamide acyltransferase -
Enterococcus faecalis (Streptococcus faecalis)
Length = 432
Score = 107 bits (257), Expect = 3e-22
Identities = 55/140 (39%), Positives = 86/140 (61%), Gaps = 1/140 (0%)
Frame = +3
Query: 9 EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEM 188
++ IIY V++S+AV T + L VPVI+ N + A + I LA++ R G L +EM
Sbjct: 283 DDGSIIYHKDVNLSIAVTTDEHLYVPVIQQADNYSIAGLAKEINRLAQEVRQGTLASKEM 342
Query: 189 DGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPI-ALNGQVVIRPMMYIALTYD 365
GGTFT++N G GS+ IIN PQ+AIL + I +R + +G + M+ + L+ D
Sbjct: 343 QGGTFTLNNTGTLGSVQSMGIINHPQAAILQVESINKRLVPTADGGFKVADMVNLCLSID 402
Query: 366 HRLIDGREAVLFLRKIKEGV 425
HR++DG++A FLR +K+ +
Sbjct: 403 HRILDGQQAGKFLRDVKDNL 422
>UniRef50_A6UGY8 Cluster: Dihydrolipoyllysine-residue
succinyltransferase; n=3; Alphaproteobacteria|Rep:
Dihydrolipoyllysine-residue succinyltransferase -
Sinorhizobium medicae WSM419
Length = 386
Score = 107 bits (257), Expect = 3e-22
Identities = 62/138 (44%), Positives = 88/138 (63%), Gaps = 6/138 (4%)
Frame = +3
Query: 33 DYVDISVAVATP-KGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTI 209
D ++I V ++ KGLVVPVIR QN++ A+I I L +AR+ L+ ++ GGTFTI
Sbjct: 237 DDINIGVGISLGGKGLVVPVIRRAQNLSLAEIAARIQDLTTRARSNALSPADVTGGTFTI 296
Query: 210 SNGGVFGSLMGTP-IINPPQSAILGMHGIFERPIA--LNG--QVVIRPMMYIALTYDHRL 374
SN GV GSL+ TP IIN PQSAILG+ + +R + ++G + IRPM Y++LT DHR
Sbjct: 297 SNHGVSGSLLATPIIINQPQSAILGVGKLDKRVVVREVDGIDTIQIRPMAYVSLTIDHRA 356
Query: 375 IDGREAVLFLRKIKEGVE 428
+DG +L + +E
Sbjct: 357 LDGHHTNAWLTEFVRVLE 374
>UniRef50_P35489 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=4; Acholeplasmataceae|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex - Acholeplasma
laidlawii
Length = 544
Score = 107 bits (257), Expect = 3e-22
Identities = 48/146 (32%), Positives = 89/146 (60%)
Frame = +3
Query: 9 EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEM 188
+ +E+ + ++++ +AV TP GL+VP I+N ++ ++ + LA+ K+++++
Sbjct: 397 DTDEVYIKKFINLGMAVDTPDGLIVPNIKNADRLSVFELASQVRSLADDTIARKISMDQQ 456
Query: 189 DGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDH 368
GGTFTI+N G G GTP+IN P+ AILG+ I +P + ++ I + ++L DH
Sbjct: 457 TGGTFTITNFGSAGIAFGTPVINYPELAILGIGKIDRKPWVVGNEIKIAHTLPLSLAVDH 516
Query: 369 RLIDGREAVLFLRKIKEGVEDPATIV 446
R+IDG + FL ++KE + +P ++
Sbjct: 517 RIIDGADGGRFLMRVKELLTNPTLLL 542
>UniRef50_Q9FC63 Cluster: Putative acyltransferase; n=1;
Streptomyces coelicolor|Rep: Putative acyltransferase -
Streptomyces coelicolor
Length = 417
Score = 107 bits (256), Expect = 4e-22
Identities = 57/147 (38%), Positives = 90/147 (61%), Gaps = 4/147 (2%)
Frame = +3
Query: 9 EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEM 188
+E I Y D +I +AV T GL+ PV++ ++T A + + LA++AR G LT +++
Sbjct: 260 DEGTITYFDSENIGIAVDTEAGLMTPVVKAAGDLTVAGLARAVHDLADRARGGHLTPDDV 319
Query: 189 DGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERP--IALNGQVVI--RPMMYIAL 356
G TFTISN G G+L T I+ P Q+AILG+ RP + + + VI R +++++L
Sbjct: 320 SGATFTISNTGSRGALFDTVIVPPNQAAILGVGATVRRPGVVRVGDEEVIGVRDLVHLSL 379
Query: 357 TYDHRLIDGREAVLFLRKIKEGVEDPA 437
+YDHRL+DG +A +L +K +E A
Sbjct: 380 SYDHRLVDGADAARYLTAVKALLESAA 406
>UniRef50_Q8F4N2 Cluster: Dihydrolipoamide acetyltransferase
component of pyruvate dehydrogenase complex E2; n=3;
Leptospira|Rep: Dihydrolipoamide acetyltransferase
component of pyruvate dehydrogenase complex E2 -
Leptospira interrogans
Length = 458
Score = 107 bits (256), Expect = 4e-22
Identities = 53/147 (36%), Positives = 82/147 (55%)
Frame = +3
Query: 12 ENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMD 191
E+ I+ +DI VAV+ GL+ P IRN + ++I I LA +AR KL E
Sbjct: 312 EDHILEHGRIDIGVAVSIEGGLITPYIRNADQKSVSEIGREIKELASRARERKLKPAEYT 371
Query: 192 GGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHR 371
GTFT+SN G+FG T +IN P++AIL + + E+P+ G +V+ + + L+ DHR
Sbjct: 372 DGTFTVSNLGMFGISSFTAVINEPEAAILAVGALVEKPVLKEGSIVVGKTLNVTLSCDHR 431
Query: 372 LIDGREAVLFLRKIKEGVEDPATIVAG 452
++DG FL ++ E P ++ G
Sbjct: 432 VVDGATGARFLSSFRDYTEYPLRLLTG 458
>UniRef50_Q97CK2 Cluster: Pyruvate dehydrogenase E2 /
dihydrolipoamide acetyltransferase; n=3;
Thermoplasma|Rep: Pyruvate dehydrogenase E2 /
dihydrolipoamide acetyltransferase - Thermoplasma
volcanium
Length = 400
Score = 107 bits (256), Expect = 4e-22
Identities = 55/141 (39%), Positives = 87/141 (61%)
Frame = +3
Query: 24 IYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTF 203
+ + Y +I +AV TP GL V V+++ + +I I AE+AR +L I+E+ TF
Sbjct: 265 LIKKYYNIGIAVDTPDGLNVFVVKDADRKSMYEITAEITDKAERARNNQLKIDEVQDSTF 324
Query: 204 TISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLIDG 383
TI+N G G ++ TPIIN P+ AILG+H + + NG + +MY++L+ DHRLIDG
Sbjct: 325 TITNVGTIGGVLSTPIINYPEVAILGVHRVMDE----NG----KKIMYLSLSCDHRLIDG 376
Query: 384 REAVLFLRKIKEGVEDPATIV 446
A F+ +K+ +EDP +++
Sbjct: 377 AVATRFIMDLKKIIEDPNSLI 397
>UniRef50_Q1AT73 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Rubrobacter xylanophilus
DSM 9941|Rep: Catalytic domain of components of various
dehydrogenase complexes - Rubrobacter xylanophilus
(strain DSM 9941 / NBRC 16129)
Length = 441
Score = 106 bits (255), Expect = 5e-22
Identities = 52/144 (36%), Positives = 90/144 (62%), Gaps = 2/144 (1%)
Frame = +3
Query: 3 VIEENEIIYRDYVDISVAVATPKG-LVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTI 179
V + + I+ R ++I +AV +G L+VPVI++ + + I + +AR +L+
Sbjct: 289 VWDGDRIVLRKRINIGIAVDLEEGALIVPVIKDADDYGIVGLARRIDEVVRRARQRRLSP 348
Query: 180 EEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIAL-NGQVVIRPMMYIAL 356
+++ GGTFT++N G GS++ TPIIN PQ+AIL I +RP+ L + + +R MM + +
Sbjct: 349 DDVSGGTFTVNNPGALGSVVSTPIINHPQAAILSAEAIVKRPVVLEDDAIAVRSMMNLEV 408
Query: 357 TYDHRLIDGREAVLFLRKIKEGVE 428
++DHR++DG A+ FL +K +E
Sbjct: 409 SFDHRILDGGAALRFLNAVKRRLE 432
>UniRef50_Q0LND0 Cluster: Dihydrolipoamide S-succinyltransferase;
n=1; Herpetosiphon aurantiacus ATCC 23779|Rep:
Dihydrolipoamide S-succinyltransferase - Herpetosiphon
aurantiacus ATCC 23779
Length = 442
Score = 106 bits (255), Expect = 5e-22
Identities = 52/138 (37%), Positives = 84/138 (60%)
Frame = +3
Query: 21 IIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGT 200
++++D V ISVAVAT GL+ PV+RN +++ I + + + R GK ++++ GGT
Sbjct: 301 LVHKD-VHISVAVATDAGLLAPVVRNCDSLSLGAISNQMRDVIGRTRDGKAGLDDLQGGT 359
Query: 201 FTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLID 380
FT+SN G+F II PPQSAIL + P+ +G++VIR +M + ++ DHR D
Sbjct: 360 FTVSNLGMFDVTNFIAIITPPQSAILAVGSTIATPVVRDGEIVIRQLMNVTVSADHRATD 419
Query: 381 GREAVLFLRKIKEGVEDP 434
G FL ++K +++P
Sbjct: 420 GASVAQFLVELKNLLQNP 437
>UniRef50_A3UGB6 Cluster: Dihydrolipoamide acetyltransferase; n=2;
Alphaproteobacteria|Rep: Dihydrolipoamide
acetyltransferase - Oceanicaulis alexandrii HTCC2633
Length = 437
Score = 106 bits (255), Expect = 5e-22
Identities = 50/138 (36%), Positives = 91/138 (65%), Gaps = 1/138 (0%)
Frame = +3
Query: 33 DYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTIS 212
D V +A ATP GL+VPVI++ +++ ++ + L + A+ GK T +E+ G T TI+
Sbjct: 297 DGVHCGIAAATPNGLMVPVIKHAESLDIWEVAAEVKRLGDAAKAGKATKDELTGSTITIT 356
Query: 213 NGGVFGSLMGTPIINPPQSAILGMHGIFERP-IALNGQVVIRPMMYIALTYDHRLIDGRE 389
+ G G ++ TP+IN P++AI+G++ + P G+VV + +M ++ ++DHR++DG E
Sbjct: 357 SLGAIGGIVTTPVINHPETAIIGVNKMQTLPRYDEAGRVVPKKIMNLSSSFDHRIVDGYE 416
Query: 390 AVLFLRKIKEGVEDPATI 443
A L ++++K +E+PAT+
Sbjct: 417 AALLVQEMKGYLENPATL 434
>UniRef50_Q0WQF7 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component 1 of pyruvate dehydrogenase
complex, mitochondrial precursor; n=4;
Magnoliophyta|Rep: Dihydrolipoyllysine-residue
acetyltransferase component 1 of pyruvate dehydrogenase
complex, mitochondrial precursor - Arabidopsis thaliana
(Mouse-ear cress)
Length = 637
Score = 106 bits (254), Expect = 6e-22
Identities = 58/146 (39%), Positives = 88/146 (60%), Gaps = 5/146 (3%)
Frame = +3
Query: 9 EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEM 188
E+ +I+ D VDIS+AVAT KGL+ P+I+N + + I L + LA+KAR+GKL E
Sbjct: 486 EKGDIVMCDSVDISIAVATEKGLMTPIIKNADQKSISAISLEVKELAQKARSGKLAPHEF 545
Query: 189 DGGTFTISNGGVFGSLMGTPIINPPQSAILGM---HGIFERPIALNG--QVVIRPMMYIA 353
GGTF+ISN G++ IINPPQ+ IL + + + E I L+G + + M +
Sbjct: 546 QGGTFSISNLGMYPVDNFCAIINPPQAGILAVGRGNKVVEPVIGLDGIEKPSVVTKMNVT 605
Query: 354 LTYDHRLIDGREAVLFLRKIKEGVED 431
L+ DHR+ DG+ F+ +++ ED
Sbjct: 606 LSADHRIFDGQVGASFMSELRSNFED 631
>UniRef50_Q5L233 Cluster: Pyruvate dehydrogenase E2; n=2;
Geobacillus|Rep: Pyruvate dehydrogenase E2 - Geobacillus
kaustophilus
Length = 436
Score = 105 bits (253), Expect = 9e-22
Identities = 55/142 (38%), Positives = 82/142 (57%)
Frame = +3
Query: 9 EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEM 188
E EI+ +++ I AV T +GL+VPVIR+ + I I L KAR G + EM
Sbjct: 289 EREEIVIHEFIHIGFAVDTDRGLLVPVIRDADQKSLFQIAKEIEELTAKARAGTIQAVEM 348
Query: 189 DGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDH 368
GGT T+SN G TPII+ PQS +LG+ + ++P+ ++ + I +M ++LTYDH
Sbjct: 349 SGGTCTVSNIGSANGSWFTPIIHYPQSCLLGIGKVEKKPVVVDDSIEIASVMPLSLTYDH 408
Query: 369 RLIDGREAVLFLRKIKEGVEDP 434
RLIDG A L + + + +P
Sbjct: 409 RLIDGMMAQHALNECQTYLSEP 430
>UniRef50_UPI0000DB7177 Cluster: PREDICTED: similar to Pyruvate
dehydrogenase protein X component, mitochondrial
precursor (Dihydrolipoamide dehydrogenase-binding
protein of pyruvate dehydrogenase complex)
(Lipoyl-containing pyruvate dehydrogenase complex
component X) (E3-binding protein) (E...; n=1; Apis
mellifera|Rep: PREDICTED: similar to Pyruvate
dehydrogenase protein X component, mitochondrial
precursor (Dihydrolipoamide dehydrogenase-binding
protein of pyruvate dehydrogenase complex)
(Lipoyl-containing pyruvate dehydrogenase complex
component X) (E3-binding protein) (E... - Apis mellifera
Length = 598
Score = 105 bits (252), Expect = 1e-21
Identities = 63/148 (42%), Positives = 86/148 (58%)
Frame = +3
Query: 9 EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEM 188
+ ++II VDIS+AVA GL+ P++ + + DI I LAEKA+TG+L EE
Sbjct: 444 KNDQIIQMPRVDISIAVAIESGLITPIVFDATAKSILDISKNIKELAEKAKTGQLKPEEF 503
Query: 189 DGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDH 368
GGTFTISN G+FG IIN PQ+AIL + E LN + M +L+YD
Sbjct: 504 QGGTFTISNLGMFGIKHFRAIINLPQTAILAVGSGREE---LNAALQKVTKMSTSLSYDR 560
Query: 369 RLIDGREAVLFLRKIKEGVEDPATIVAG 452
R ID +A FL +K +EDP+ ++AG
Sbjct: 561 RAIDEDQAADFLAVLKAMLEDPSFLIAG 588
>UniRef50_Q63HZ8 Cluster: Lipoamide acyltransferase component of
branched-chain alpha-keto acid dehydrogenase complex;
n=14; Burkholderia|Rep: Lipoamide acyltransferase
component of branched-chain alpha-keto acid
dehydrogenase complex - Burkholderia pseudomallei
(Pseudomonas pseudomallei)
Length = 483
Score = 105 bits (252), Expect = 1e-21
Identities = 49/135 (36%), Positives = 83/135 (61%)
Frame = +3
Query: 39 VDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNG 218
V + +A + GL+VPV+R+ + I +A LA+ AR G+ +E+ G T TI++
Sbjct: 346 VHLGIATQSKAGLMVPVVRHAEARDPWSIAAEVARLADAARAGRAERDELSGSTITITSL 405
Query: 219 GVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLIDGREAVL 398
G G + TP+IN P+ I+G++ I ERP+ G VV R +M ++ ++DHR+IDG +A
Sbjct: 406 GALGGIASTPVINSPEVGIVGVNRIVERPMFRGGAVVARKLMNLSSSFDHRVIDGMDAAE 465
Query: 399 FLRKIKEGVEDPATI 443
F++ ++ +E PA +
Sbjct: 466 FIQAVRGLLEQPALL 480
>UniRef50_Q1NYU2 Cluster: Dihydrolipoamide acyltransferase E2
component; n=1; Candidatus Sulcia muelleri str. Hc
(Homalodisca coagulata)|Rep: Dihydrolipoamide
acyltransferase E2 component - Candidatus Sulcia
muelleri str. Hc (Homalodisca coagulata)
Length = 371
Score = 105 bits (252), Expect = 1e-21
Identities = 55/145 (37%), Positives = 82/145 (56%)
Frame = +3
Query: 12 ENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMD 191
E I+Y + ++I +AVA GL+VPVI V + I I KA+ K+ E++
Sbjct: 226 EKSILYHNNINIGIAVALEDGLIVPVINQVNEKSLRQISFEIKEKVIKAKEKKIQSNELE 285
Query: 192 GGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHR 371
G TFT+SN G+FG T IIN P S IL + I ++PI N ++VI LT DHR
Sbjct: 286 GSTFTVSNLGMFGIDSFTSIINQPNSCILSVGSIKKKPIINNDKIVIGHTTKFTLTCDHR 345
Query: 372 LIDGREAVLFLRKIKEGVEDPATIV 446
+IDG +L+ +K+ +++P I+
Sbjct: 346 IIDGAVGSDYLKSLKKLLQEPLNII 370
>UniRef50_A7HHV9 Cluster: Pyruvate dehydrogenase complex
dihydrolipoamide acetyltransferase; n=4;
Proteobacteria|Rep: Pyruvate dehydrogenase complex
dihydrolipoamide acetyltransferase - Anaeromyxobacter
sp. Fw109-5
Length = 574
Score = 105 bits (252), Expect = 1e-21
Identities = 53/142 (37%), Positives = 84/142 (59%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEE 185
+E ++++ + Y I A TP GLVVPV+++ +I +A LA+KAR GKL + +
Sbjct: 427 LEGDQLVLKRYFHIGFAADTPGGLVVPVVKDADRKGVLEIARELAELAQKARDGKLQLAD 486
Query: 186 MDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYD 365
M GGTF++S+ G G TPIIN P+ AILG+ +P+ + R M+ ++L+YD
Sbjct: 487 MQGGTFSVSSLGGIGGTAFTPIINAPEVAILGVSRSATKPVWDGERFAPRLMLPLSLSYD 546
Query: 366 HRLIDGREAVLFLRKIKEGVED 431
HR++DG A F + + + D
Sbjct: 547 HRVVDGAAAARFTSHLAQLLAD 568
>UniRef50_A0PU60 Cluster: Dihydrolipoamide S-acetyltransferase E2
component PdhC; n=3; Mycobacterium|Rep: Dihydrolipoamide
S-acetyltransferase E2 component PdhC - Mycobacterium
ulcerans (strain Agy99)
Length = 389
Score = 105 bits (252), Expect = 1e-21
Identities = 54/139 (38%), Positives = 78/139 (56%)
Frame = +3
Query: 39 VDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNG 218
V + VAT +GL+VPVI + MT ++ A L AR G L ++ G TFT+SN
Sbjct: 251 VHLGFGVATERGLLVPVIADAHRMTTRELVCRAAELITGAREGTLAPGQLRGWTFTVSNY 310
Query: 219 GVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLIDGREAVL 398
G G G P+IN P +AILGM I RP+ +VV+RP M + +DHR+ DG +
Sbjct: 311 GALGVDDGVPVINHPDAAILGMGSIKPRPVVRGDEVVVRPTMSLTCVFDHRVADGAQVAR 370
Query: 399 FLRKIKEGVEDPATIVAGL 455
F+ +++ +E P T + L
Sbjct: 371 FICELRGLIEAPETALLDL 389
>UniRef50_A0CWR1 Cluster: Chromosome undetermined scaffold_3, whole
genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_3,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 628
Score = 105 bits (252), Expect = 1e-21
Identities = 56/136 (41%), Positives = 82/136 (60%), Gaps = 1/136 (0%)
Frame = +3
Query: 42 DISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNGG 221
DIS+AVAT GL+ P++ N + I T+ LA+KA+ KL +E GGTFTISN G
Sbjct: 492 DISIAVATDAGLITPIVFNAGSKGLGTIASTVKELADKAKANKLKPQEFIGGTFTISNLG 551
Query: 222 VFGSLMGTPIINPPQSAILGMHGIFERPIA-LNGQVVIRPMMYIALTYDHRLIDGREAVL 398
+FG +INPPQSAIL + +R + +GQ + M + L+ DHR++DG
Sbjct: 552 MFGIDQFIAVINPPQSAILAVGKTSKRFVPDEHGQPKVESQMDVTLSCDHRVVDGAVGAQ 611
Query: 399 FLRKIKEGVEDPATIV 446
+L++ K +EDP T++
Sbjct: 612 WLQRFKYYIEDPNTLL 627
>UniRef50_P06959 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=62; Proteobacteria|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex - Escherichia coli
(strain K12)
Length = 630
Score = 105 bits (252), Expect = 1e-21
Identities = 55/139 (39%), Positives = 82/139 (58%)
Frame = +3
Query: 30 RDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTI 209
+ Y++I VAV TP GLVVPV ++V ++ + +++KAR GKLT EM GG FTI
Sbjct: 491 KKYINIGVAVDTPNGLVVPVFKDVNKKGIIELSRELMTISKKARDGKLTAGEMQGGCFTI 550
Query: 210 SNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLIDGRE 389
S+ G G+ PI+N P+ AILG+ P+ + V R M+ I+L++DHR+IDG +
Sbjct: 551 SSIGGLGTTHFAPIVNAPEVAILGVSKSAMEPVWNGKEFVPRLMLPISLSFDHRVIDGAD 610
Query: 390 AVLFLRKIKEGVEDPATIV 446
F+ I + D +V
Sbjct: 611 GARFITIINNTLSDIRRLV 629
>UniRef50_Q2GI07 Cluster: Pyruvate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase; n=6;
Anaplasmataceae|Rep: Pyruvate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase -
Ehrlichia chaffeensis (strain Arkansas)
Length = 416
Score = 104 bits (249), Expect = 3e-21
Identities = 54/141 (38%), Positives = 82/141 (58%)
Frame = +3
Query: 12 ENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMD 191
+++I+ +DISVAV+ GL+ P+I + +I + LA KA++GKL EE
Sbjct: 271 DDKIVVFPSIDISVAVSIDNGLITPIIFGADKKSLLEISREVKALASKAKSGKLKPEEFQ 330
Query: 192 GGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHR 371
GG FT+SN G+FG I+NPPQS I+ + +R + +N Q+ I ++ + L+ DHR
Sbjct: 331 GGGFTVSNLGMFGIKEFYAIVNPPQSCIMSVGCSEKRAMVVNEQICISNVVTVTLSVDHR 390
Query: 372 LIDGREAVLFLRKIKEGVEDP 434
+IDG A FL K +E P
Sbjct: 391 VIDGVLAAKFLNCFKSYLEKP 411
>UniRef50_Q0LRZ3 Cluster: Dihydrolipoamide acetyltransferase, long
form; n=1; Caulobacter sp. K31|Rep: Dihydrolipoamide
acetyltransferase, long form - Caulobacter sp. K31
Length = 415
Score = 104 bits (249), Expect = 3e-21
Identities = 57/145 (39%), Positives = 77/145 (53%)
Frame = +3
Query: 12 ENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMD 191
++ II VDISVAVAT GL+ P++R A I + LA +AR G+L E
Sbjct: 270 DDAIIQFQDVDISVAVATDGGLITPIVRQADRRGLASISAEVRTLAARAREGRLEPAEFQ 329
Query: 192 GGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHR 371
GG+FTISN G+FG + IINPPQS IL + RP+ V +M L+ DHR
Sbjct: 330 GGSFTISNLGMFGVRAFSAIINPPQSCILAVGAAERRPVVRGEACVPATVMTCTLSVDHR 389
Query: 372 LIDGREAVLFLRKIKEGVEDPATIV 446
+DG +L K +E P ++
Sbjct: 390 AVDGVVGARYLAAFKSLIEQPLRLM 414
>UniRef50_A5IXN4 Cluster: Dihydrolipoamide acetyltransferase
component ofpyruvate deshydrogenase complex; n=1;
Mycoplasma agalactiae|Rep: Dihydrolipoamide
acetyltransferase component ofpyruvate deshydrogenase
complex - Mycoplasma agalactiae
Length = 244
Score = 104 bits (249), Expect = 3e-21
Identities = 56/142 (39%), Positives = 83/142 (58%), Gaps = 1/142 (0%)
Frame = +3
Query: 12 ENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMD 191
E ++ Y ++I +AV TP GL VPVIR V+N++ DI+ I L+ AR KL + +M
Sbjct: 97 EGKVYYPGTLNIGIAVDTPFGLFVPVIRGVENLSIIDIQKEIVRLSTLARDKKLKMSDMS 156
Query: 192 GGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIF-ERPIALNGQVVIRPMMYIALTYDH 368
GG F I+N G G L G+PI+N +AI I E + G V R +MY+++ DH
Sbjct: 157 GGCFAITNVGSAGVLFGSPIMNKGNTAISATGAIIDELKLNKEGAVENRKVMYLSIAADH 216
Query: 369 RLIDGREAVLFLRKIKEGVEDP 434
+ +DG + F +IKE +E+P
Sbjct: 217 QWVDGADMARFQGRIKELIENP 238
>UniRef50_Q7WED2 Cluster: Probable 2-oxo acid dehydrogenases
acyltransferase; n=2; Bacteria|Rep: Probable 2-oxo acid
dehydrogenases acyltransferase - Bordetella
bronchiseptica (Alcaligenes bronchisepticus)
Length = 416
Score = 103 bits (248), Expect = 3e-21
Identities = 57/143 (39%), Positives = 81/143 (56%), Gaps = 2/143 (1%)
Frame = +3
Query: 12 ENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMD 191
++ I+ +D+ VAV+T +GL+ PV+ + + + DI L + R GK T E+M
Sbjct: 263 DDHIVQFQGIDVGVAVSTERGLMAPVLHGLDHASLDDIAAQSGALLGRVRAGKATREDMS 322
Query: 192 GGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFE--RPIALNGQVVIRPMMYIALTYD 365
GG +ISN G+F PIINPPQSAILG+ I E RP G +R M + L D
Sbjct: 323 GGAISISNAGMFNVTYMAPIINPPQSAILGVGSIRELFRPDE-QGAPALRREMGLVLAAD 381
Query: 366 HRLIDGREAVLFLRKIKEGVEDP 434
HRL DG A+ FL + + ++DP
Sbjct: 382 HRLHDGASALAFLNHVIDLLQDP 404
>UniRef50_Q39ET0 Cluster: Dihydrolipoamide acetyltransferase; n=42;
Bacteria|Rep: Dihydrolipoamide acetyltransferase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 548
Score = 103 bits (248), Expect = 3e-21
Identities = 54/132 (40%), Positives = 79/132 (59%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEE 185
++ + ++++ Y + A TP GLVVPVIR+ DI +A L++ AR GKL ++
Sbjct: 401 LDGDNLVFKQYYHVGFAADTPNGLVVPVIRDADKKGLVDIAKEMAELSKAARDGKLKPDQ 460
Query: 186 MDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYD 365
M GG F+IS+ G G TPIIN P+ AILG+ +P+ Q V R + ++L+YD
Sbjct: 461 MQGGCFSISSLGGIGGTNFTPIINAPEVAILGLSRGQMKPVWDGKQFVPRLTLPLSLSYD 520
Query: 366 HRLIDGREAVLF 401
HR+IDG EA F
Sbjct: 521 HRVIDGAEAARF 532
>UniRef50_Q2B858 Cluster: Pyruvate dehydrogenase E2; n=1; Bacillus
sp. NRRL B-14911|Rep: Pyruvate dehydrogenase E2 -
Bacillus sp. NRRL B-14911
Length = 391
Score = 103 bits (247), Expect = 5e-21
Identities = 56/139 (40%), Positives = 84/139 (60%), Gaps = 2/139 (1%)
Frame = +3
Query: 45 ISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISN-GG 221
I VAV GL+VPVI N + T A+I + L KA G+L +E GGTFT+SN G
Sbjct: 252 IGVAVNAEDGLIVPVIGNAEEKTIAEIAEDLQNLTRKALDGRLLAKETAGGTFTVSNVGP 311
Query: 222 VFGSLMGTPIINPPQSAILGMHGIFERPIA-LNGQVVIRPMMYIALTYDHRLIDGREAVL 398
+ GS TPII PQ++I+ +H + P+ + Q+VIR +M +++++DHR+ DG AV
Sbjct: 312 LNGSTGATPIILHPQTSIISLHKTKKMPVVDKDDQIVIRSIMKLSMSFDHRIADGAAAVG 371
Query: 399 FLRKIKEGVEDPATIVAGL 455
F + E +E+P ++ L
Sbjct: 372 FTNRFAELIENPKLMLLEL 390
>UniRef50_Q1V1J3 Cluster: Dihydrolipoamide S-acetyltransferase; n=3;
Bacteria|Rep: Dihydrolipoamide S-acetyltransferase -
Candidatus Pelagibacter ubique HTCC1002
Length = 434
Score = 103 bits (246), Expect = 6e-21
Identities = 53/140 (37%), Positives = 84/140 (60%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEE 185
IE +I + Y + +AV TP GL+VP IR+ N + + I + ++++ R K+ +E
Sbjct: 285 IENGKITIKKYFHVGIAVDTPHGLMVPKIRSADNKSISYISNELKTVSDQCRNLKIDKKE 344
Query: 186 MDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYD 365
GG+ TI++ G G TPIIN P+ AILG+ ++ I +NG+ R M+ ++L+YD
Sbjct: 345 FFGGSMTITSLGGIGGSFFTPIINYPEVAILGVGKAQKKQIFINGKFETRTMLPLSLSYD 404
Query: 366 HRLIDGREAVLFLRKIKEGV 425
HR+IDG EA F +KE +
Sbjct: 405 HRIIDGAEAARFNNDLKENL 424
>UniRef50_A3VK82 Cluster: Putative uncharacterized protein; n=1;
Rhodobacterales bacterium HTCC2654|Rep: Putative
uncharacterized protein - Rhodobacterales bacterium
HTCC2654
Length = 472
Score = 103 bits (246), Expect = 6e-21
Identities = 58/139 (41%), Positives = 80/139 (57%)
Frame = +3
Query: 33 DYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTIS 212
+ DI++AVA GL+ PV+RNV DI LA KAR L+ +EM GGTFT+S
Sbjct: 334 EQADIAMAVAIDGGLITPVVRNVGGRGLRDIAADAKALAGKARDRALSGDEMTGGTFTLS 393
Query: 213 NGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLIDGREA 392
N G+FG IINPPQ+AIL + G ++G V +M + L+ DHR +DG A
Sbjct: 394 NLGMFGVREFDAIINPPQAAILAVGGPRREAREVDGGVGFVSVMSVTLSADHRAVDGALA 453
Query: 393 VLFLRKIKEGVEDPATIVA 449
FLR ++ +E P +V+
Sbjct: 454 AEFLRTLRGLIEAPLRLVS 472
>UniRef50_Q6PLQ2 Cluster: Dihydrolipoamide S-acetyltransferase; n=1;
Chlamydomonas reinhardtii|Rep: Dihydrolipoamide
S-acetyltransferase - Chlamydomonas reinhardtii
Length = 643
Score = 103 bits (246), Expect = 6e-21
Identities = 54/132 (40%), Positives = 76/132 (57%)
Frame = +3
Query: 39 VDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNG 218
VDISVAVAT +GL+ P++R + + LA KA+ KL EE GG+FT+SN
Sbjct: 503 VDISVAVATERGLITPIVRAADVKGLLAVSREVRALALKAKDNKLKPEEFTGGSFTVSNL 562
Query: 219 GVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLIDGREAVL 398
G++G + IINPPQ+AIL + G ER + + GQ +R M + L+ D R+ DG A
Sbjct: 563 GMYGLTHFSAIINPPQAAILAVGGATERVVLVGGQPAVRSAMSVTLSADGRVYDGELAGA 622
Query: 399 FLRKIKEGVEDP 434
L + +E P
Sbjct: 623 VLAAFRRHMEQP 634
>UniRef50_P45118 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=11; Proteobacteria|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex - Haemophilus
influenzae
Length = 567
Score = 102 bits (245), Expect = 8e-21
Identities = 52/146 (35%), Positives = 84/146 (57%)
Frame = +3
Query: 9 EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEM 188
+ +I + Y++I VAV TP GLVVPV +NV ++ + +++KAR GKLT +M
Sbjct: 421 DAQRLILKKYINIGVAVDTPNGLVVPVFKNVNKKGIIELSRELMEVSKKAREGKLTASDM 480
Query: 189 DGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDH 368
GG FTIS+ G G+ PI+N P+ AILG+ P+ + R ++ ++L++DH
Sbjct: 481 QGGCFTISSLGGIGTTHFAPIVNAPEVAILGVSKSSMEPVWNGKEFAPRLILPMSLSFDH 540
Query: 369 RLIDGREAVLFLRKIKEGVEDPATIV 446
R+IDG + F+ + + D +V
Sbjct: 541 RVIDGADGARFISYLGSVLADLRRLV 566
>UniRef50_Q820A3 Cluster: AceF; dihydrolipoamide acetyltransferase
component of pyruvate dehydrogenase complex (E2)
protein; n=1; Nitrosomonas europaea|Rep: AceF;
dihydrolipoamide acetyltransferase component of pyruvate
dehydrogenase complex (E2) protein - Nitrosomonas
europaea
Length = 453
Score = 102 bits (244), Expect = 1e-20
Identities = 55/130 (42%), Positives = 76/130 (58%)
Frame = +3
Query: 12 ENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMD 191
E+++I + Y + A TP GLVVPVIR+ I + L+ AR GKL +M
Sbjct: 308 ESQLIIKRYYHLGFAADTPNGLVVPVIRDADQKGVIGIAEELTRLSSLAREGKLKPGDMQ 367
Query: 192 GGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHR 371
G +FTIS+ G G TPIIN P+ AILG+ +P+ NGQ V R ++ ++L+YDHR
Sbjct: 368 GASFTISSLGGIGGTGFTPIINAPEVAILGVSRASLKPVYQNGQFVPRLVLPLSLSYDHR 427
Query: 372 LIDGREAVLF 401
+IDG A F
Sbjct: 428 VIDGASAARF 437
>UniRef50_P10802 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=47; Bacteria|Rep: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex - Azotobacter vinelandii
Length = 638
Score = 102 bits (244), Expect = 1e-20
Identities = 57/142 (40%), Positives = 82/142 (57%)
Frame = +3
Query: 21 IIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGT 200
+I + YV I AV TP GL+VPVIRNV + + A LAEKAR+ KL + M G
Sbjct: 496 LIRKKYVHIGFAVDTPDGLLVPVIRNVDQKSLLQLAAEAAELAEKARSKKLGADAMQGAC 555
Query: 201 FTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLID 380
FTIS+ G G TPI+N P+ AILG+ +P+ R M+ ++L+YDHR+I+
Sbjct: 556 FTISSLGHIGGTAFTPIVNAPEVAILGVSKASMQPVWDGKAFQPRLMLPLSLSYDHRVIN 615
Query: 381 GREAVLFLRKIKEGVEDPATIV 446
G A F +++ + + D I+
Sbjct: 616 GAAAARFTKRLGDLLADIRAIL 637
>UniRef50_Q6KH63 Cluster: Pyruvate dehydrogenase E2 component
dihydrolipoamide acetyltransferase; n=6; Mycoplasma|Rep:
Pyruvate dehydrogenase E2 component dihydrolipoamide
acetyltransferase - Mycoplasma mobile
Length = 453
Score = 101 bits (243), Expect = 1e-20
Identities = 51/142 (35%), Positives = 79/142 (55%)
Frame = +3
Query: 9 EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEM 188
+ +E++Y ++I +AV T GL+VPVI+N + +I I LA AR K+ +E+
Sbjct: 306 QASELVYSGTLNIGIAVDTEAGLMVPVIKNADKLNIIEIAKEITRLAVAARDKKIKADEL 365
Query: 189 DGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDH 368
G FT++N GSL G P+IN P AI G+ I + PI +V +M + + DH
Sbjct: 366 KGSDFTVTNYASVGSLFGIPVINYPDMAIAGIGVIKDEPIVTKNGIVAGKIMNLTVAADH 425
Query: 369 RLIDGREAVLFLRKIKEGVEDP 434
R +DG F +K+K +E+P
Sbjct: 426 RWVDGATIGRFAQKVKHFLENP 447
>UniRef50_Q4FS31 Cluster: Dihydrolipoyllysine acetyltransferase
component of pyruvate dehydrogenase complex; n=2;
Psychrobacter|Rep: Dihydrolipoyllysine acetyltransferase
component of pyruvate dehydrogenase complex -
Psychrobacter arcticum
Length = 578
Score = 101 bits (243), Expect = 1e-20
Identities = 54/148 (36%), Positives = 85/148 (57%), Gaps = 2/148 (1%)
Frame = +3
Query: 9 EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEM 188
+ ++I R V++ +AVAT GL+VPVI+N I + I LA KAR KL+ +++
Sbjct: 430 DNTQVILRKSVNMGIAVATDDGLIVPVIKNAHEKGIKQIAIEIGELAIKARDKKLSTKDL 489
Query: 189 DGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRP--MMYIALTY 362
G +FTIS+ G+ G TP++N PQ ILG +P + P M+ ++L+Y
Sbjct: 490 QGASFTISSQGILGGTAFTPLVNWPQVGILGASEATMQPKWNAAKQAFEPRLMLPLSLSY 549
Query: 363 DHRLIDGREAVLFLRKIKEGVEDPATIV 446
DHR+I+G +A +F R + + DP I+
Sbjct: 550 DHRVINGADAAVFTRYVATLLADPRRIL 577
>UniRef50_A6W003 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=2; Marinomonas|Rep: Catalytic
domain of components of various dehydrogenase complexes
- Marinomonas sp. MWYL1
Length = 414
Score = 101 bits (243), Expect = 1e-20
Identities = 59/140 (42%), Positives = 84/140 (60%), Gaps = 8/140 (5%)
Frame = +3
Query: 36 YVDISVAVATP---KGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFT 206
+ DI++ V T GL+VPV++ VQ +I + +KAR GKL +M GTFT
Sbjct: 272 FEDINIGVGTALGDDGLIVPVVKQVQEKNLFEIASALQQQTDKARQGKLAAADMRDGTFT 331
Query: 207 ISNGGVFGSLMGTP-IINPPQSAILGMHGIFERPIA--LNGQ--VVIRPMMYIALTYDHR 371
ISN GV GSL TP IIN PQ AILG+ + +R + ++G+ +VIRP Y++L+ DHR
Sbjct: 332 ISNHGVSGSLFATPIIINQPQVAILGIGKLEKRAVVEEVDGEDTIVIRPKCYVSLSIDHR 391
Query: 372 LIDGREAVLFLRKIKEGVED 431
+D + LFL E +E+
Sbjct: 392 ALDAYQTNLFLSHFVEVIEN 411
>UniRef50_A6GG26 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvatedehydrogenase
complex; n=1; Plesiocystis pacifica SIR-1|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvatedehydrogenase complex - Plesiocystis pacifica
SIR-1
Length = 436
Score = 101 bits (243), Expect = 1e-20
Identities = 53/140 (37%), Positives = 80/140 (57%)
Frame = +3
Query: 15 NEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDG 194
++ I R V++ +AVA GLVVPV+R + I L + AR L E+M G
Sbjct: 288 DKAIIRGDVNVGIAVAVEDGLVVPVVRYADQKSLEAISRESKALGKSARDKHLRPEDMSG 347
Query: 195 GTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRL 374
GTFT+SN G+FG +INP ++ IL + I RP+ G++VIR M + ++ DHR+
Sbjct: 348 GTFTVSNLGMFGIESFAAVINPGEAGILAVGAIESRPVVQGGELVIRKRMKMTISADHRV 407
Query: 375 IDGREAVLFLRKIKEGVEDP 434
DG A +L K++ +E+P
Sbjct: 408 TDGAVAAKWLTKVRGYLENP 427
>UniRef50_O45279 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 337
Score = 101 bits (243), Expect = 1e-20
Identities = 56/138 (40%), Positives = 80/138 (57%), Gaps = 1/138 (0%)
Frame = +3
Query: 39 VDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNG 218
VDISVAVATP GL+ P++ N + I + L+ AR KL ++ GG+FTISN
Sbjct: 185 VDISVAVATPTGLITPIVENSDILGVLAISSKVKELSGLARESKLKPQQFQGGSFTISNL 244
Query: 219 GVFGSLMG-TPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLIDGREAV 395
G+FGS+ T IINPPQ AIL + G ++++GQ+ + +M + L +D R I A
Sbjct: 245 GMFGSVTNFTAIINPPQCAILTIGGTRSEVVSVDGQLETQKLMGVNLCFDGRAISEECAK 304
Query: 396 LFLRKIKEGVEDPATIVA 449
FL E + DP ++A
Sbjct: 305 RFLLHFSESLSDPELLIA 322
>UniRef50_Q59638 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=7; Proteobacteria|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex - Pseudomonas
aeruginosa
Length = 547
Score = 101 bits (243), Expect = 1e-20
Identities = 56/142 (39%), Positives = 83/142 (58%)
Frame = +3
Query: 21 IIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGT 200
+I + YV I AV TP GL+VPVIR+V + + A LA+KAR KL+ + M G
Sbjct: 405 LIRKKYVHIGFAVDTPDGLLVPVIRDVDRKSLLQLAAEAADLADKARNKKLSADAMQGAC 464
Query: 201 FTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLID 380
FTIS+ G G TPI+N P+ AILG+ +P+ R M+ ++L+YDHR+I+
Sbjct: 465 FTISSLGHIGGTGFTPIVNAPEVAILGVSKATMQPVWDGKAFQPRLMLPLSLSYDHRVIN 524
Query: 381 GREAVLFLRKIKEGVEDPATIV 446
G A F +++ E + D T++
Sbjct: 525 GAAAARFTKRLGELLADIRTLL 546
>UniRef50_Q9PJZ6 Cluster: 2-oxo acid dehydrogenase, E2 component,
lipoamide acyltransferase; n=9; Chlamydiaceae|Rep: 2-oxo
acid dehydrogenase, E2 component, lipoamide
acyltransferase - Chlamydia muridarum
Length = 410
Score = 101 bits (242), Expect = 2e-20
Identities = 56/143 (39%), Positives = 86/143 (60%), Gaps = 2/143 (1%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPK-GLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIE 182
++ + I+ + V++ VAV K G+VVPVI N Q+ I +A L+ +AR KL
Sbjct: 263 LDGDTIVLKKAVNVGVAVNLNKEGVVVPVIHNCQDRGLVSIAKALADLSSRARASKLDAS 322
Query: 183 EMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIAL-NGQVVIRPMMYIALT 359
E GG+ T++N G+ G+L+G PII P+ AILG+ I +R + + + IR MMY+ LT
Sbjct: 323 EAKGGSVTLTNFGMTGALIGMPIIRYPEVAILGIGTIQKRVVVREDDSLAIRKMMYVTLT 382
Query: 360 YDHRLIDGREAVLFLRKIKEGVE 428
+DHR++DG FL +K +E
Sbjct: 383 FDHRVLDGIYGGEFLTALKNRLE 405
>UniRef50_Q8D2N2 Cluster: AceF protein; n=1; Wigglesworthia
glossinidia endosymbiont of Glossina brevipalpis|Rep:
AceF protein - Wigglesworthia glossinidia brevipalpis
Length = 496
Score = 101 bits (242), Expect = 2e-20
Identities = 55/141 (39%), Positives = 83/141 (58%)
Frame = +3
Query: 9 EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEM 188
++N++I + Y +I +AV+T GLVVPVI +V +I + ++ KAR KL +M
Sbjct: 350 DKNKLILKKYFNIGIAVSTDYGLVVPVIFDVDKKGIIEISHELFNISNKARNKKLISRDM 409
Query: 189 DGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDH 368
GG FTISN G G TPIIN P+ AILG+ +P+ + M+ ++L+YDH
Sbjct: 410 TGGCFTISNLGGIGGREFTPIINYPEVAILGVSQASIQPMWNGSSFSPKLMLPLSLSYDH 469
Query: 369 RLIDGREAVLFLRKIKEGVED 431
R+IDG E F+ +K+ + D
Sbjct: 470 RVIDGSEGAKFIIFLKKIISD 490
>UniRef50_Q3WAF9 Cluster: Biotin/lipoyl attachment:Catalytic domain
of components of various dehydrogenase complexes:E3
binding; n=2; Frankia|Rep: Biotin/lipoyl
attachment:Catalytic domain of components of various
dehydrogenase complexes:E3 binding - Frankia sp. EAN1pec
Length = 585
Score = 101 bits (242), Expect = 2e-20
Identities = 50/147 (34%), Positives = 83/147 (56%)
Frame = +3
Query: 9 EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEM 188
E EI + +++ +AVA P+GLVVP I + + D+ ++ L E AR +L ++
Sbjct: 437 ENAEIQVHERINLGIAVAGPRGLVVPNIPDAGSRGLVDLARSLHSLTEAARADRLRPADL 496
Query: 189 DGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDH 368
GGT TI+N GV G G P++NP ++AIL + I P G++ +R + ++AL++DH
Sbjct: 497 SGGTITITNVGVLGVDTGAPVLNPGEAAILALGAIRPAPWVHEGELAVRTVAHLALSFDH 556
Query: 369 RLIDGREAVLFLRKIKEGVEDPATIVA 449
R++DG L + + DP +A
Sbjct: 557 RVVDGELGSAVLADVAAVLADPVIALA 583
>UniRef50_O59816 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex, mitochondrial precursor; n=1;
Schizosaccharomyces pombe|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex, mitochondrial
precursor - Schizosaccharomyces pombe (Fission yeast)
Length = 483
Score = 101 bits (242), Expect = 2e-20
Identities = 57/139 (41%), Positives = 78/139 (56%), Gaps = 3/139 (2%)
Frame = +3
Query: 39 VDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNG 218
VDIS+AVATP GL+ PVIRN + A+I ++AR KL EE GGTFTISN
Sbjct: 344 VDISMAVATPSGLITPVIRNTHALGLAEISTLAKDYGQRARNNKLKPEEYQGGTFTISNL 403
Query: 219 GVFGSLMGTPIINPPQSAILGMHGIFERPI---ALNGQVVIRPMMYIALTYDHRLIDGRE 389
G+F T IINPPQ+ IL + + + + P+M L+ DHR++DG
Sbjct: 404 GMFPVDQFTAIINPPQACILAVGTTVDTVVPDSTSEKGFKVAPIMKCTLSSDHRVVDGAM 463
Query: 390 AVLFLRKIKEGVEDPATIV 446
A F +K+ +E+P I+
Sbjct: 464 AARFTTALKKILENPLEIM 482
>UniRef50_Q1LSX2 Cluster: Pyruvate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase; n=1;
Baumannia cicadellinicola str. Hc (Homalodisca
coagulata)|Rep: Pyruvate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase -
Baumannia cicadellinicola subsp. Homalodisca coagulata
Length = 358
Score = 101 bits (241), Expect = 2e-20
Identities = 51/138 (36%), Positives = 80/138 (57%)
Frame = +3
Query: 18 EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGG 197
++I + Y++I +AV TP GL+VPV NV + + LA+KA TGKL +M
Sbjct: 215 KLICKKYINIGIAVDTPSGLLVPVCHNVNKKGIITLSQEVINLAQKAHTGKLIPSDMQDS 274
Query: 198 TFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLI 377
FTISN G G + TPIIN P+ AILG+ + +P+ + + ++ ++L+YDHR+I
Sbjct: 275 CFTISNLGNIGGMHFTPIINAPEVAILGVSKTYFKPVWNGEKFIPLQVLPLSLSYDHRVI 334
Query: 378 DGREAVLFLRKIKEGVED 431
+G + F+ I + D
Sbjct: 335 NGGDGARFINFIGHIMSD 352
>UniRef50_Q4QJI5 Cluster: Dihydrolipoamide branched chain
transacylase, putative; n=2; Leishmania|Rep:
Dihydrolipoamide branched chain transacylase, putative -
Leishmania major
Length = 477
Score = 101 bits (241), Expect = 2e-20
Identities = 51/139 (36%), Positives = 83/139 (59%), Gaps = 1/139 (0%)
Frame = +3
Query: 42 DISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNGG 221
+I A+ TP GL+VPV+++V+ + DI + L E+ ++ KLT ++M GGTFT+SN G
Sbjct: 338 NIGFAMDTPNGLIVPVVKHVERKSILDIANDMQVLIERGKSNKLTTQDMTGGTFTLSNIG 397
Query: 222 VFGSLMGTPIINPPQSAILGMHGIFERP-IALNGQVVIRPMMYIALTYDHRLIDGREAVL 398
V G+ + TP++ PPQ AI + + + P NG + ++ ++ T DHR+IDG V
Sbjct: 398 VIGATVTTPVLLPPQVAIGAIGRLQKLPRFDANGSLYAANLICVSFTADHRVIDGASMVR 457
Query: 399 FLRKIKEGVEDPATIVAGL 455
F K+ +E P ++ L
Sbjct: 458 FANTYKQLLEHPENMLVDL 476
>UniRef50_Q98FT5 Cluster: Dihydrolipoamide acetyltransferase
homoserine dehydrogenase; n=23; Alphaproteobacteria|Rep:
Dihydrolipoamide acetyltransferase homoserine
dehydrogenase - Rhizobium loti (Mesorhizobium loti)
Length = 454
Score = 100 bits (240), Expect = 3e-20
Identities = 51/141 (36%), Positives = 77/141 (54%)
Frame = +3
Query: 12 ENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMD 191
E ++ + D+ VAV+ P GL+ P+IR+ T + I + LA +AR+ KL EE
Sbjct: 309 ETAMVKHKHADVGVAVSIPGGLITPIIRHADEKTLSTISNEMKDLASRARSRKLKPEEYQ 368
Query: 192 GGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHR 371
GGT +SN G+FG +INPP + IL + ER + NG++ I +M + L+ DHR
Sbjct: 369 GGTTAVSNLGMFGIKDFAAVINPPHATILAVGAGEERAVVKNGEIKIATVMSVTLSTDHR 428
Query: 372 LIDGREAVLFLRKIKEGVEDP 434
+DG L K +E+P
Sbjct: 429 AVDGALGAELLVAFKRLIENP 449
>UniRef50_Q08V09 Cluster: Pyruvate dehydrogenase complex
dihydrolipoamide acetyltransferase; n=2;
Cystobacterineae|Rep: Pyruvate dehydrogenase complex
dihydrolipoamide acetyltransferase - Stigmatella
aurantiaca DW4/3-1
Length = 533
Score = 100 bits (240), Expect = 3e-20
Identities = 47/147 (31%), Positives = 84/147 (57%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEE 185
++ N I+ D+ +AVA GL+ P+I++ I LAE+AR L +E
Sbjct: 386 LQGNTILQFATADVGIAVAIEDGLITPIIKDADQKGLQAISTEARELAERARKKALKPDE 445
Query: 186 MDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYD 365
GG+ T+SN G++G +INPPQ+AI+ + + ++ + +GQ+ +R ++ + L+ D
Sbjct: 446 YTGGSITVSNLGMYGIDQFVAVINPPQAAIIAVGAVADKAVVRDGQITVRKILTVTLSGD 505
Query: 366 HRLIDGREAVLFLRKIKEGVEDPATIV 446
HR+IDG +LR++K +E P ++
Sbjct: 506 HRVIDGATGAEYLRELKNLLEHPMRLL 532
>UniRef50_A5V4B2 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Sphingomonas wittichii
RW1|Rep: Catalytic domain of components of various
dehydrogenase complexes - Sphingomonas wittichii RW1
Length = 420
Score = 100 bits (240), Expect = 3e-20
Identities = 60/139 (43%), Positives = 84/139 (60%), Gaps = 6/139 (4%)
Frame = +3
Query: 33 DYVDISVAVAT-PKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTI 209
D V+I + A KGLVVPV+ Q ++ I + + E+AR KLT +M GGTFTI
Sbjct: 279 DDVNIGIGTALGDKGLVVPVVSKCQELSLLGIAKRLTEMVERARANKLTPADMRGGTFTI 338
Query: 210 SNGGVFGSLMGTP-IINPPQSAILGMHGIFERPIA--LNG--QVVIRPMMYIALTYDHRL 374
SN GV GSL TP IIN PQSAILG+ +R + ++G + IR + Y++LT DHR+
Sbjct: 339 SNHGVSGSLFATPIIINQPQSAILGIGKTEKRVVVREVDGVDTIQIRSLAYVSLTIDHRV 398
Query: 375 IDGREAVLFLRKIKEGVED 431
+DG + +L E +E+
Sbjct: 399 VDGHQTNGWLSAFVETLEN 417
>UniRef50_A3WC78 Cluster: Pyruvate dehydrogenase E2 component; n=2;
Alphaproteobacteria|Rep: Pyruvate dehydrogenase E2
component - Erythrobacter sp. NAP1
Length = 463
Score = 100 bits (240), Expect = 3e-20
Identities = 53/131 (40%), Positives = 74/131 (56%)
Frame = +3
Query: 42 DISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNGG 221
DISVAVA P GL+ PVI A I + LA KAR GKL E GGT ++SN G
Sbjct: 328 DISVAVAAPSGLITPVITEADTKGLAQISKEMKELAGKARDGKLQPHEYQGGTASLSNLG 387
Query: 222 VFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLIDGREAVLF 401
+FG +INPPQ IL + + P ++G++ +++ + ++DHR IDG E
Sbjct: 388 MFGIKQFDAVINPPQGMILAVGAGQQVPYVIDGEIKPATVLHASGSFDHRAIDGAEGAQL 447
Query: 402 LRKIKEGVEDP 434
+ IK+ VE+P
Sbjct: 448 MEAIKQLVENP 458
>UniRef50_Q6L1M0 Cluster: Dihydrolipoamide acetyltransferase
component of pyruvate dehydrogenase complex; n=2;
Thermoplasmatales|Rep: Dihydrolipoamide
acetyltransferase component of pyruvate dehydrogenase
complex - Picrophilus torridus
Length = 386
Score = 100 bits (240), Expect = 3e-20
Identities = 53/131 (40%), Positives = 82/131 (62%)
Frame = +3
Query: 42 DISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNGG 221
+I +AV +P GL V V+++V + +I + I LAEKAR+ KL ++++ TF+++N G
Sbjct: 254 NIGIAVDSPYGLTVVVVKDVDKKSIFEISMEIRELAEKARSNKLEMDDVRDSTFSVTNIG 313
Query: 222 VFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLIDGREAVLF 401
G + TPIIN P+ AIL ++ ++G +R +Y+ L DHRLIDG EA F
Sbjct: 314 AIGGIYSTPIINYPEVAILAVN--TRTNAFIDGS--MRSGVYVTLACDHRLIDGAEAARF 369
Query: 402 LRKIKEGVEDP 434
++KIKE +E P
Sbjct: 370 IKKIKEIIEQP 380
>UniRef50_Q8EVQ0 Cluster: Dihydrolipoamide acetyltransferase of
pyruvate dehydrogenase E2 component; n=1; Mycoplasma
penetrans|Rep: Dihydrolipoamide acetyltransferase of
pyruvate dehydrogenase E2 component - Mycoplasma
penetrans
Length = 478
Score = 100 bits (239), Expect = 4e-20
Identities = 50/139 (35%), Positives = 84/139 (60%)
Frame = +3
Query: 21 IIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGT 200
+I R+ V+I +AV T GL+VP I+N ++ +I +IA +A +ART K+T+ ++ GT
Sbjct: 336 LILRNEVNIGIAVDTKDGLIVPNIKNADKLSIIEIAKSIADIAARARTKKITMADLQKGT 395
Query: 201 FTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLID 380
F++SN G G G P+IN P+ AI G+ + + Q+V R +M + + DHR +D
Sbjct: 396 FSVSNYGSLGIEFGVPVINYPEVAIAGLGTASNKIKKVGIQMVERKVMVLTIAADHRWVD 455
Query: 381 GREAVLFLRKIKEGVEDPA 437
G + F ++K+ +E+ A
Sbjct: 456 GGDIARFANQVKQYLENIA 474
>UniRef50_Q6F713 Cluster: Dihydrolipoamide S-acetyltransferase, E2
component of the pyruvate dehydrogenase complex; n=2;
Moraxellaceae|Rep: Dihydrolipoamide S-acetyltransferase,
E2 component of the pyruvate dehydrogenase complex -
Acinetobacter sp. (strain ADP1)
Length = 661
Score = 100 bits (239), Expect = 4e-20
Identities = 50/137 (36%), Positives = 81/137 (59%)
Frame = +3
Query: 21 IIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGT 200
++ R + + +AVATP GL VPV+RN T I + + + +KAR KL+ +++ G
Sbjct: 519 VLLRKEIHMGIAVATPDGLTVPVLRNPDQKTIKQIAVELGVIGQKARDKKLSPKDLQGAN 578
Query: 201 FTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLID 380
FTIS+ G G TP++N PQ AILG+ +P+ R M+ ++L+YDHR+I+
Sbjct: 579 FTISSLGAIGGTAFTPLVNWPQVAILGISPATMQPVWNGKDFDPRLMLPLSLSYDHRVIN 638
Query: 381 GREAVLFLRKIKEGVED 431
G +A F K+ + ++D
Sbjct: 639 GADAARFTNKLTKLLQD 655
>UniRef50_A7BC27 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 448
Score = 100 bits (239), Expect = 4e-20
Identities = 56/150 (37%), Positives = 87/150 (58%), Gaps = 2/150 (1%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEE 185
+E+ + + V + A TP+GL+VPVIR+ Q + LA A G L+ +
Sbjct: 299 LEDGVLTEFEQVHLGFACDTPRGLLVPVIRSAQALGLKAFSDEAKRLAGGAIDGSLSPDF 358
Query: 186 MDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERP-IALNGQVVIRPMMYIALTY 362
+ GGTFT+SN G FG TP+IN PQ+AILG+ I RP +A +G + + + ++LT
Sbjct: 359 LSGGTFTVSNIGSFGIETFTPVINLPQTAILGVGAITPRPTVAADGSIGVEQRLNLSLTI 418
Query: 363 DHRLIDGREAVLFLRKIKEGVED-PATIVA 449
DH++IDG + FLR + +E+ T++A
Sbjct: 419 DHQVIDGADGARFLRDLVAAIENIDVTVLA 448
>UniRef50_A3CMZ5 Cluster: Dihydrolipoamide acetyl transferase, E2
component, putative; n=2; Streptococcus|Rep:
Dihydrolipoamide acetyl transferase, E2 component,
putative - Streptococcus sanguinis (strain SK36)
Length = 419
Score = 100 bits (239), Expect = 4e-20
Identities = 58/144 (40%), Positives = 88/144 (61%), Gaps = 4/144 (2%)
Frame = +3
Query: 27 YRDYVDISVAVATP--KGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGT 200
Y++ DI + +AT GLVVPVIR+V +T AD+ L I A +AR G L G T
Sbjct: 276 YQEVEDIHIGIATALSDGLVVPVIRHVDKLTLADLGLAIKTEANQARKGTLDPALYSGST 335
Query: 201 FTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALN--GQVVIRPMMYIALTYDHRL 374
F+I+N G G TPI+N P+ AILG+ G + +AL+ GQV + ++ ++LT+DH++
Sbjct: 336 FSITNLGGAGIEYFTPILNTPEVAILGV-GALQTSLALDSQGQVYEQKLLPLSLTFDHQV 394
Query: 375 IDGREAVLFLRKIKEGVEDPATIV 446
+DG+ A FL + + +E P +V
Sbjct: 395 VDGQPAAEFLASLADKLESPYDLV 418
>UniRef50_A0H5V3 Cluster: Dihydrolipoamide S-succinyltransferase;
n=1; Chloroflexus aggregans DSM 9485|Rep:
Dihydrolipoamide S-succinyltransferase - Chloroflexus
aggregans DSM 9485
Length = 435
Score = 100 bits (239), Expect = 4e-20
Identities = 49/142 (34%), Positives = 86/142 (60%)
Frame = +3
Query: 21 IIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGT 200
I+ ++I VAVA GLV PV+R+ + + I I +A +AR GK+ E++G T
Sbjct: 293 IVRHSQINIGVAVALDDGLVAPVVRDADKKSVSTISAEIRDMALRAREGKIKQNELEGAT 352
Query: 201 FTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLID 380
F ++N G+FG + II+ PQ+A L + + + P+ + Q+VI +M + L+ DHR+ID
Sbjct: 353 FQVTNLGMFGIIEFGSIISVPQAASLAVGTVRKVPVVRDDQIVIGQVMNLTLSADHRVID 412
Query: 381 GREAVLFLRKIKEGVEDPATIV 446
G +L+++++ +E P +I+
Sbjct: 413 GAVGAQYLQELRKLLESPVSII 434
>UniRef50_A4RXN8 Cluster: Predicted protein; n=3; cellular
organisms|Rep: Predicted protein - Ostreococcus
lucimarinus CCE9901
Length = 421
Score = 100 bits (239), Expect = 4e-20
Identities = 54/137 (39%), Positives = 84/137 (61%), Gaps = 2/137 (1%)
Frame = +3
Query: 42 DISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNGG 221
DISVAV T +GL+VP++R+ + I + LA +AR+G LT ++M GGTFTISN G
Sbjct: 285 DISVAVQTERGLMVPIVRSACCLGLKSISAEVKSLAGRARSGSLTPQDMTGGTFTISNLG 344
Query: 222 VFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIA--LTYDHRLIDGREAV 395
+FG I+NPPQ+AIL + G + + N + ++ ++ L+ DHR++DG
Sbjct: 345 MFGVKNFAAIVNPPQAAILAVGGA-RKEVVKNAEGGYEEVLVMSATLSCDHRVVDGAVGA 403
Query: 396 LFLRKIKEGVEDPATIV 446
+L+ K +EDP T++
Sbjct: 404 QWLQSFKCYLEDPMTML 420
>UniRef50_P10515 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex, mitochondrial precursor; n=46; cellular
organisms|Rep: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex, mitochondrial precursor - Homo sapiens (Human)
Length = 614
Score = 100 bits (239), Expect = 4e-20
Identities = 53/138 (38%), Positives = 80/138 (57%), Gaps = 2/138 (1%)
Frame = +3
Query: 39 VDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNG 218
VD+SVAV+TP GL+ P++ N I + LA KAR GKL E GGTFTISN
Sbjct: 476 VDVSVAVSTPAGLITPIVFNAHIKGVETIANDVVSLATKAREGKLQPHEFQGGTFTISNL 535
Query: 219 GVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQ--VVIRPMMYIALTYDHRLIDGREA 392
G+FG + IINPPQ+ IL + ++ + + + + MM + L+ DHR++DG
Sbjct: 536 GMFGIKNFSAIINPPQACILAIGASEDKLVPADNEKGFDVASMMSVTLSCDHRVVDGAVG 595
Query: 393 VLFLRKIKEGVEDPATIV 446
+L + ++ +E P T++
Sbjct: 596 AQWLAEFRKYLEKPITML 613
>UniRef50_Q8RBW8 Cluster: Dihydrolipoamide acyltransferases; n=1;
Thermoanaerobacter tengcongensis|Rep: Dihydrolipoamide
acyltransferases - Thermoanaerobacter tengcongensis
Length = 399
Score = 99.5 bits (237), Expect = 7e-20
Identities = 51/148 (34%), Positives = 84/148 (56%)
Frame = +3
Query: 3 VIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIE 182
VI+ ++++ V + AVA L+VPVI+N + ++ + L + G + E
Sbjct: 250 VIDGDDMVVPAEVHLGFAVARGDELLVPVIKNAHRLNLNEMAVERRRLTDAVLQGIIKPE 309
Query: 183 EMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTY 362
E+ GGTFT++N G +G TP++ P QSAILG+ I ERP+ NG + M ++LT
Sbjct: 310 ELQGGTFTVTNLGTYGVDFFTPVLYPKQSAILGIGRIVERPVLENGNIRSAQFMTLSLTV 369
Query: 363 DHRLIDGREAVLFLRKIKEGVEDPATIV 446
DH++I+G A FL ++ E + P ++
Sbjct: 370 DHQVINGAPAARFLNRLAELLSQPEVLL 397
>UniRef50_Q5P915 Cluster: Pyruvate dehydrogenase multienzyme
complex, dihydrolipoamide acetyltransferase component;
n=16; Proteobacteria|Rep: Pyruvate dehydrogenase
multienzyme complex, dihydrolipoamide acetyltransferase
component - Azoarcus sp. (strain EbN1) (Aromatoleum
aromaticum (strain EbN1))
Length = 583
Score = 99.5 bits (237), Expect = 7e-20
Identities = 55/130 (42%), Positives = 75/130 (57%)
Frame = +3
Query: 12 ENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMD 191
E ++Y+ Y +I+ A TP GLVVPVI+N + +I LA+KAR GKL +M
Sbjct: 438 EMSLVYKKYFNIAFAADTPNGLVVPVIKNADRKSVFEIAAESGELAKKARDGKLGPADMS 497
Query: 192 GGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHR 371
G FTIS+ G G PI+N P+ AILG++ +PI Q V R + ++LT DHR
Sbjct: 498 GACFTISSLGGIGGTYFAPIVNAPEVAILGVNKSAMKPIWDGKQFVPRLTLPMSLTADHR 557
Query: 372 LIDGREAVLF 401
+IDG A F
Sbjct: 558 VIDGALATRF 567
>UniRef50_Q0VRX7 Cluster: Pyruvate dehydrogenase, E2 component; n=4;
Proteobacteria|Rep: Pyruvate dehydrogenase, E2 component
- Alcanivorax borkumensis (strain SK2 / ATCC 700651 /
DSM 11573)
Length = 564
Score = 99.5 bits (237), Expect = 7e-20
Identities = 55/137 (40%), Positives = 81/137 (59%)
Frame = +3
Query: 21 IIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGT 200
+I + Y++I +AV TP GLVVPVI++ I + LAEKAR KLT +M GGT
Sbjct: 422 LIEKRYINIGIAVDTPNGLVVPVIKDADKKGLKAIAQEMDELAEKARNRKLTPADMKGGT 481
Query: 201 FTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLID 380
F+IS+ G G TPI+N P+ AILG+ +P+ + R ++ ++L+YDHR+ID
Sbjct: 482 FSISSLGGIGGTAFTPIVNWPEVAILGVSRSDMQPVWDGSEFQPRLILPMSLSYDHRVID 541
Query: 381 GREAVLFLRKIKEGVED 431
G A F + + + D
Sbjct: 542 GAAAARFTTYLSQLLTD 558
>UniRef50_A5UU13 Cluster: Dihydrolipoyllysine-residue
succinyltransferase; n=4; Bacteria|Rep:
Dihydrolipoyllysine-residue succinyltransferase -
Roseiflexus sp. RS-1
Length = 459
Score = 99.5 bits (237), Expect = 7e-20
Identities = 54/149 (36%), Positives = 83/149 (55%), Gaps = 2/149 (1%)
Frame = +3
Query: 12 ENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMD 191
++ II V+I++AVA GL+ PV+ N Q+ + I + AR GK+T + +
Sbjct: 311 DDGIILHPTVNIAIAVALESGLMAPVVANCQDRSLGSIARETKRIVALAREGKITPDLLQ 370
Query: 192 GGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIAL--NGQVVIRPMMYIALTYD 365
GGTFT+SN G++G T II PPQ+A L + I P + +VV + +M + L+ D
Sbjct: 371 GGTFTVSNLGMYGIPEFTSIITPPQAASLAVGAIRRTPAFKDDSDEVVAKHLMMLTLSAD 430
Query: 366 HRLIDGREAVLFLRKIKEGVEDPATIVAG 452
HR+ DG E FL +K +E P ++ G
Sbjct: 431 HRVTDGAEVARFLNDVKRLLEQPLALLVG 459
>UniRef50_A1KCD0 Cluster: Putative uncharacterized protein; n=1;
Azoarcus sp. BH72|Rep: Putative uncharacterized protein
- Azoarcus sp. (strain BH72)
Length = 237
Score = 99.5 bits (237), Expect = 7e-20
Identities = 56/142 (39%), Positives = 79/142 (55%)
Frame = +3
Query: 3 VIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIE 182
++ E E+ D ++I VAVA GL+VPVIR A + LAE AR G LT
Sbjct: 91 LMREKEVELVDDINIGVAVALDDGLMVPVIRQADTKPVAALAAETRQLAEGARAGALTGG 150
Query: 183 EMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTY 362
GTFT++N G +PIINPPQ AILG+ ++ + +G +V P++ + L +
Sbjct: 151 AYQRGTFTVTNLGSTPVDRFSPIINPPQVAILGVGRTRQQAVVKDGAIVAAPVVNLTLVF 210
Query: 363 DHRLIDGREAVLFLRKIKEGVE 428
DHR +DG A LFL +I +E
Sbjct: 211 DHRAVDGYPAALFLGEIARRLE 232
>UniRef50_A7THD4 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 484
Score = 99.5 bits (237), Expect = 7e-20
Identities = 59/151 (39%), Positives = 86/151 (56%), Gaps = 5/151 (3%)
Frame = +3
Query: 9 EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEM 188
+EN I + VD+SVAVATP GL+ P+++NV + I + L ++AR KL EE
Sbjct: 334 KENVIRQFENVDVSVAVATPTGLITPIVKNVNSKGLVSISNEVKDLVKRARINKLNPEEF 393
Query: 189 DGGTFTISNGGVFGSL-MGTPIINPPQSAILGMHGIFERPI----ALNGQVVIRPMMYIA 353
GGT ISN G+ ++ M T IINPPQSAIL + P+ + NG ++ I
Sbjct: 394 QGGTICISNLGMNNAVSMFTSIINPPQSAILAVGTTKRIPVEDVTSKNG-FTFNDVITIT 452
Query: 354 LTYDHRLIDGREAVLFLRKIKEGVEDPATIV 446
T+DHR IDG + F+ +K +E+P ++
Sbjct: 453 GTFDHRTIDGAKGGEFMHALKTIIENPLQLL 483
>UniRef50_A4XHV3 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Caldicellulosiruptor
saccharolyticus DSM 8903|Rep: Catalytic domain of
components of various dehydrogenase complexes -
Caldicellulosiruptor saccharolyticus (strain ATCC 43494
/ DSM 8903)
Length = 460
Score = 98.7 bits (235), Expect = 1e-19
Identities = 51/146 (34%), Positives = 84/146 (57%)
Frame = +3
Query: 12 ENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMD 191
++++ Y V + AV T +GL+VP I N + I L + R G + + +
Sbjct: 314 DDKMRYFKNVHLGFAVDTERGLMVPTIFNSNKKSLNQISKEAKELIQLCRKGTINPDLLK 373
Query: 192 GGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHR 371
G TFT++N G FG TP++NPPQ+ ILG++ I R NGQ+ P + ++LT+DHR
Sbjct: 374 GATFTVTNLGSFGIEGFTPVLNPPQTGILGVNTIVMRAKEQNGQITYYPAIGLSLTFDHR 433
Query: 372 LIDGREAVLFLRKIKEGVEDPATIVA 449
+DG +A FL+ +K+ +E+ ++A
Sbjct: 434 ALDGADAARFLQDLKKWLENFELLLA 459
>UniRef50_Q57Z16 Cluster: Dihydrolipoamide branched chain
transacylase, putative; n=3; Trypanosoma|Rep:
Dihydrolipoamide branched chain transacylase, putative -
Trypanosoma brucei
Length = 439
Score = 98.3 bits (234), Expect = 2e-19
Identities = 53/137 (38%), Positives = 79/137 (57%), Gaps = 1/137 (0%)
Frame = +3
Query: 45 ISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNGGV 224
I A+ TPKGLVVPV+R+VQ + A++ + L R ++ + M GTFT+SN G
Sbjct: 300 IGFAMDTPKGLVVPVVRDVQQKSVAELVHEVNELVTLGRKSQIPPDRMKDGTFTLSNIGP 359
Query: 225 FGSLMGTPIINPPQSAILGMHGIFERP-IALNGQVVIRPMMYIALTYDHRLIDGREAVLF 401
G++ TP++NPPQ AI + I + P +G VV ++ ++ T DHR+IDG V F
Sbjct: 360 IGAIYATPMLNPPQVAIGAIGRIQQLPRFDASGNVVRANILAMSWTADHRVIDGATLVRF 419
Query: 402 LRKIKEGVEDPATIVAG 452
K +E P ++AG
Sbjct: 420 SNAFKRCLESPGLLIAG 436
>UniRef50_A1SYC2 Cluster: Dihydrolipoamide dehydrogenase E3
component of 3 enzyme complexes; n=1; Psychromonas
ingrahamii 37|Rep: Dihydrolipoamide dehydrogenase E3
component of 3 enzyme complexes - Psychromonas
ingrahamii (strain 37)
Length = 431
Score = 97.9 bits (233), Expect = 2e-19
Identities = 52/132 (39%), Positives = 74/132 (56%)
Frame = +3
Query: 39 VDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNG 218
+DISVAV+T GL+ P++ N + + L K R+GKL E GG FTISN
Sbjct: 291 IDISVAVSTDDGLMTPIVFNADRKGLITLSQNMKSLVSKTRSGKLQPNEYQGGGFTISNL 350
Query: 219 GVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLIDGREAVL 398
G++ IINPPQS IL + + P+ + Q++I +M L+ DHR+IDG A
Sbjct: 351 GMYDIDSFNAIINPPQSCILAVGRAKKIPVVKDDQILIANVMNCTLSVDHRVIDGSVAAE 410
Query: 399 FLRKIKEGVEDP 434
FL+ K +E+P
Sbjct: 411 FLQTFKFYIENP 422
>UniRef50_O66119 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=31; Bacteria|Rep: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex - Zymomonas mobilis
Length = 440
Score = 97.9 bits (233), Expect = 2e-19
Identities = 49/145 (33%), Positives = 82/145 (56%)
Frame = +3
Query: 15 NEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDG 194
++++ DISVAV+ GL+ P+++ + + + + + L +AR G+L +E G
Sbjct: 295 DQMLQFSQADISVAVSVEGGLITPILKQADTKSLSALSVEMKELIARAREGRLQPQEYQG 354
Query: 195 GTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRL 374
GT +ISN G+FG +INPPQ++IL + RP ++ + I + I ++DHR+
Sbjct: 355 GTSSISNMGMFGIKQFNAVINPPQASILAIGSGERRPWVIDDAITIATVATITGSFDHRV 414
Query: 375 IDGREAVLFLRKIKEGVEDPATIVA 449
IDG +A F+ K VE P I+A
Sbjct: 415 IDGADAAAFMSAFKHLVEKPLGILA 439
>UniRef50_A4CQ51 Cluster: Lipoamide acyltransferase component of
branched-chain alpha-keto acid dehydrogenase complex;
n=13; Bacteroidetes|Rep: Lipoamide acyltransferase
component of branched-chain alpha-keto acid
dehydrogenase complex - Robiginitalea biformata HTCC2501
Length = 476
Score = 97.5 bits (232), Expect = 3e-19
Identities = 50/146 (34%), Positives = 87/146 (59%), Gaps = 5/146 (3%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPKG-LVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIE 182
++ + +I + +++ +A A P G L+VPVIRN + + + LA +AR L +
Sbjct: 323 VDGDRVIKKKQINLGMAAALPDGNLIVPVIRNADQLNLVGMARAVNDLATRARNNALKPD 382
Query: 183 EMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIAL---NGQVV-IRPMMYI 350
E+ GT+T++N G FGS+ GTPIIN PQ IL + I + P + +G + IR M++
Sbjct: 383 EVRDGTYTVTNVGSFGSVFGTPIINQPQVGILALGAIRKVPAVIETPSGDFIGIRSKMFL 442
Query: 351 ALTYDHRLIDGREAVLFLRKIKEGVE 428
+ +YDHR+++G LF++ + + +E
Sbjct: 443 SHSYDHRVVNGALGGLFVKAVADYLE 468
>UniRef50_Q54TR7 Cluster: Dihydrolipoyl transacylase; n=1;
Dictyostelium discoideum AX4|Rep: Dihydrolipoyl
transacylase - Dictyostelium discoideum AX4
Length = 517
Score = 97.5 bits (232), Expect = 3e-19
Identities = 51/147 (34%), Positives = 89/147 (60%), Gaps = 1/147 (0%)
Frame = +3
Query: 9 EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEM 188
++ EIIY++Y +I +A+ +P+GL+VP I+NV++ + +I + L E + G LT +M
Sbjct: 367 DQTEIIYKNYHNIGIAMDSPQGLLVPNIKNVESKSIFEIAKELNRLQELSGKGLLTPNDM 426
Query: 189 DGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERP-IALNGQVVIRPMMYIALTYD 365
GGTFT+SN G G L +P++ P+ I + I P + V+ + +M I+ + D
Sbjct: 427 SGGTFTLSNIGTIGGLHSSPVLLLPEVCIGAIGKIQSLPRFNKHHAVITQSIMNISWSGD 486
Query: 366 HRLIDGREAVLFLRKIKEGVEDPATIV 446
HR+IDG F +K+ +E+P+T++
Sbjct: 487 HRVIDGATMARFSNALKDYLENPSTMI 513
>UniRef50_Q5KIM3 Cluster: Dihydrolipoyllysine-residue
acetyltransferase, putative; n=2; Basidiomycota|Rep:
Dihydrolipoyllysine-residue acetyltransferase, putative
- Cryptococcus neoformans (Filobasidiella neoformans)
Length = 479
Score = 97.5 bits (232), Expect = 3e-19
Identities = 58/139 (41%), Positives = 78/139 (56%), Gaps = 4/139 (2%)
Frame = +3
Query: 42 DISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNGG 221
DI VAVATP GL+ P+I++V A I LA +AR GKL EE GG+FTISN G
Sbjct: 341 DICVAVATPNGLITPIIKDVGAKGLATISAETKALASRARDGKLKPEEYQGGSFTISNLG 400
Query: 222 VFGSLMGTPIINPPQSAILGMHGIFER----PIALNGQVVIRPMMYIALTYDHRLIDGRE 389
+FG T IINPPQS IL + + P G ++ +M + L+ DHR +DG
Sbjct: 401 MFGVDEFTAIINPPQSCILAVGKTTTKLELAPEDPKGFKAVQ-VMKVTLSADHRTVDGAV 459
Query: 390 AVLFLRKIKEGVEDPATIV 446
+L+ +E +E P T +
Sbjct: 460 GARWLKAFREYMEQPLTFM 478
>UniRef50_Q6KCM0 Cluster: Dihydrolipoyl transacetylase; n=1; Euglena
gracilis|Rep: Dihydrolipoyl transacetylase - Euglena
gracilis
Length = 434
Score = 97.1 bits (231), Expect = 4e-19
Identities = 60/136 (44%), Positives = 78/136 (57%)
Frame = +3
Query: 39 VDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNG 218
VDISVAVATP GL+ PV+ N +I I LA AR GKLT E+ GGTFTISN
Sbjct: 309 VDISVAVATPTGLITPVVYNADLKGLKEISNDIRTLAALAREGKLTPEQYIGGTFTISNL 368
Query: 219 GVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLIDGREAVL 398
G +G T IINPPQ+ IL + E NG +M + L+ DHR++DG
Sbjct: 369 GSYGVKHFTAIINPPQACILAVGAAQE-----NG------LMSVTLSCDHRVVDGAVGAT 417
Query: 399 FLRKIKEGVEDPATIV 446
+L+ K VE P++++
Sbjct: 418 WLQAFKGYVETPSSLL 433
>UniRef50_Q1EGH6 Cluster: Pyruvate dehydrogenase E2 subunit; n=1;
Euplotes sp. BB-2004|Rep: Pyruvate dehydrogenase E2
subunit - Euplotes sp. BB-2004
Length = 459
Score = 96.7 bits (230), Expect = 5e-19
Identities = 51/134 (38%), Positives = 79/134 (58%), Gaps = 2/134 (1%)
Frame = +3
Query: 39 VDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNG 218
VD+SVAV+TP GL+ P+I+ I + LA +AR KL ++E GGT ++SN
Sbjct: 321 VDVSVAVSTPTGLITPIIKEANLKGLETISAEMKDLAARARENKLKLDEFQGGTISVSNL 380
Query: 219 GVFGSLMGTPIINPPQSAILGMHGIFER--PIALNGQVVIRPMMYIALTYDHRLIDGREA 392
G+FG + IINPPQ+ IL + G +R P G+ ++ L+ DHR++DG EA
Sbjct: 381 GMFGVSHFSAIINPPQACILAIGGSQQRVLPGDEEGKYRTANVISFTLSSDHRVVDGAEA 440
Query: 393 VLFLRKIKEGVEDP 434
++ + K+ +E+P
Sbjct: 441 AIWGQHFKKYIENP 454
>UniRef50_O00330 Cluster: Pyruvate dehydrogenase protein X
component, mitochondrial precursor; n=26; Amniota|Rep:
Pyruvate dehydrogenase protein X component,
mitochondrial precursor - Homo sapiens (Human)
Length = 501
Score = 96.7 bits (230), Expect = 5e-19
Identities = 54/139 (38%), Positives = 84/139 (60%), Gaps = 6/139 (4%)
Frame = +3
Query: 36 YVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISN 215
++DISVAVAT KGL+ P+I++ +I ++ L++KAR GKL EE GG+F+ISN
Sbjct: 360 FIDISVAVATDKGLLTPIIKDAAAKGIQEIADSVKALSKKARDGKLLPEEYQGGSFSISN 419
Query: 216 GGVFGSLMGTPIINPPQSAILGMHGIFERPIAL------NGQVVIRPMMYIALTYDHRLI 377
G+FG T +INPPQ+ IL + G F + L N ++ R ++ + ++ D R++
Sbjct: 420 LGMFGIDEFTAVINPPQACILAV-GRFRPVLKLTEDEEGNAKLQQRQLITVTMSSDSRVV 478
Query: 378 DGREAVLFLRKIKEGVEDP 434
D A FL+ K +E+P
Sbjct: 479 DDELATRFLKSFKANLENP 497
>UniRef50_Q4L1A5 Cluster: Dihydrolipoamide acetyltransferase; n=2;
Mycoplasma synoviae|Rep: Dihydrolipoamide
acetyltransferase - Mycoplasma synoviae
Length = 309
Score = 95.9 bits (228), Expect = 9e-19
Identities = 47/132 (35%), Positives = 75/132 (56%)
Frame = +3
Query: 39 VDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNG 218
+++ AV T GL+VPVI+N ++ D+ ++ LA AR + ++M FT++N
Sbjct: 172 INLGFAVDTEAGLMVPVIKNANALSVLDLAREVSRLASAARNKTIKPDDMKNAGFTVTNY 231
Query: 219 GVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLIDGREAVL 398
G GSL G P+IN P+ AILG+ I + G +V +MY+ + DHR IDG +
Sbjct: 232 GSVGSLWGVPVINYPELAILGVGAIQDEAFVEKGTLVAGKVMYLTVAADHRWIDGADVGR 291
Query: 399 FLRKIKEGVEDP 434
F ++K+ +E P
Sbjct: 292 FASRVKQLLESP 303
>UniRef50_Q13GQ6 Cluster: Dihydrolipoamide acyltransferase (E2)
component of 2-oxoacid dehydrogenase complexes; n=1;
Burkholderia xenovorans LB400|Rep: Dihydrolipoamide
acyltransferase (E2) component of 2-oxoacid
dehydrogenase complexes - Burkholderia xenovorans
(strain LB400)
Length = 428
Score = 95.9 bits (228), Expect = 9e-19
Identities = 51/137 (37%), Positives = 83/137 (60%), Gaps = 2/137 (1%)
Frame = +3
Query: 42 DISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNGG 221
D+ VAV T +GL+VPV+R+V ++ + +A+ G+L EM GG T+SN G
Sbjct: 291 DVGVAVHTERGLLVPVLRDVGRQALGEVARHASEAIGRAQAGQLNAAEMAGGAITVSNAG 350
Query: 222 VFGSLMGTPIINPPQSAILGMHGIFE--RPIALNGQVVIRPMMYIALTYDHRLIDGREAV 395
+ + T IINP QS ILG+ + + RP A +GQ ++ + + L+ DHR++DG A+
Sbjct: 351 MHDVTLMTSIINPGQSMILGVGSVRQVFRPDA-HGQPALKNEVGLVLSVDHRVLDGVTAL 409
Query: 396 LFLRKIKEGVEDPATIV 446
FLR++ +E PA+++
Sbjct: 410 KFLRQVVAAIERPASLL 426
>UniRef50_Q9M724 Cluster: Branched chain alpha-keto acid
dehydrogenase E2 subunit; n=9; Magnoliophyta|Rep:
Branched chain alpha-keto acid dehydrogenase E2 subunit
- Arabidopsis thaliana (Mouse-ear cress)
Length = 483
Score = 95.9 bits (228), Expect = 9e-19
Identities = 54/147 (36%), Positives = 83/147 (56%), Gaps = 1/147 (0%)
Frame = +3
Query: 9 EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEM 188
E EII + +I VA+AT GLVVP I+NVQ+++ +I ++ L A KL E++
Sbjct: 333 ESLEIILKGSHNIGVAMATEHGLVVPNIKNVQSLSLLEITKELSRLQHLAANNKLNPEDV 392
Query: 189 DGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERP-IALNGQVVIRPMMYIALTYD 365
GGT T+SN G G G+P++N P+ AI+ + I + P + G V +M + + D
Sbjct: 393 TGGTITLSNIGAIGGKFGSPLLNLPEVAIIALGRIEKVPKFSKEGTVYPASIMMVNIAAD 452
Query: 366 HRLIDGREAVLFLRKIKEGVEDPATIV 446
HR++DG F + KE VE P ++
Sbjct: 453 HRVLDGATVARFCCQWKEYVEKPELLM 479
>UniRef50_P75392 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=2; Mycoplasma|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex - Mycoplasma
pneumoniae
Length = 402
Score = 95.9 bits (228), Expect = 9e-19
Identities = 45/141 (31%), Positives = 79/141 (56%)
Frame = +3
Query: 9 EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEM 188
E N I+ V++ +AV TP GL+VP I+ Q + DI I LA +AR+ ++ + ++
Sbjct: 255 ERNLIVLNKDVNVGIAVDTPDGLIVPNIKQAQTKSVVDIAKDIVDLANRARSKQIKLPDL 314
Query: 189 DGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDH 368
GT +++N G G+ GTPII P+ I+ + ER + G V + ++ + + DH
Sbjct: 315 SKGTISVTNFGSLGAAFGTPIIKHPEMCIVATGNMEERVVRAEGGVAVHTILPLTIAADH 374
Query: 369 RLIDGREAVLFLRKIKEGVED 431
R +DG + F ++I + +E+
Sbjct: 375 RWVDGADVGRFGKEIAKQIEE 395
>UniRef50_Q68FJ5 Cluster: MGC86218 protein; n=3; Tetrapoda|Rep:
MGC86218 protein - Xenopus laevis (African clawed frog)
Length = 478
Score = 95.5 bits (227), Expect = 1e-18
Identities = 55/137 (40%), Positives = 80/137 (58%), Gaps = 5/137 (3%)
Frame = +3
Query: 39 VDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNG 218
+DIS+AVAT +GL+ P+I+ + +I T LA+KAR GKL EE GG+F+ISN
Sbjct: 336 IDISIAVATDRGLITPIIKQAASKGIQEIAATAKVLAQKARDGKLLPEEYQGGSFSISNL 395
Query: 219 GVFGSLMGTPIINPPQSAIL--GMHGI---FERPIALNGQVVIRPMMYIALTYDHRLIDG 383
G+FG + +INPPQS IL G + F N Q+ + +M + L+ D RL+D
Sbjct: 396 GMFGITGFSAVINPPQSCILAVGRSRVELGFSEGEEGNPQLCQKQVMNVTLSSDGRLVDD 455
Query: 384 REAVLFLRKIKEGVEDP 434
A FL ++ +E+P
Sbjct: 456 ELATKFLECFRKNLENP 472
>UniRef50_Q7NB00 Cluster: AceF; n=1; Mycoplasma gallisepticum|Rep:
AceF - Mycoplasma gallisepticum
Length = 440
Score = 95.5 bits (227), Expect = 1e-18
Identities = 50/141 (35%), Positives = 85/141 (60%), Gaps = 2/141 (1%)
Frame = +3
Query: 15 NEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDG 194
N ++ + +++ +AV T GL+VP I++ Q+ + ++ + LAEKAR+ K+ + ++
Sbjct: 295 NRLVLKKKINLGIAVDTADGLMVPNIKSAQDKSVIELAREVNNLAEKARSKKIGLADLAD 354
Query: 195 GTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIAL--NGQVVIRPMMYIALTYDH 368
GT +++N G G+L GTPII P+ AI+ G E +A Q+VI+ +M I + DH
Sbjct: 355 GTISVTNFGSIGALFGTPIIKFPEVAIIAT-GTVEEKLARTPENQIVIKQIMPITIAADH 413
Query: 369 RLIDGREAVLFLRKIKEGVED 431
R IDG + F + +KE VE+
Sbjct: 414 RWIDGADIGRFAKTLKEIVEN 434
>UniRef50_A2WZU5 Cluster: Putative uncharacterized protein; n=2; Oryza
sativa|Rep: Putative uncharacterized protein - Oryza
sativa subsp. indica (Rice)
Length = 1812
Score = 95.5 bits (227), Expect = 1e-18
Identities = 57/139 (41%), Positives = 80/139 (57%), Gaps = 3/139 (2%)
Frame = +3
Query: 39 VDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISN- 215
V+I+VAV T GL VPVIR+ I + +A++AR L E+ +GGTFTISN
Sbjct: 1673 VNINVAVQTEHGLFVPVIRDADKKGLGTIAEEVKQVAQRARDNSLKPEDYEGGTFTISNL 1732
Query: 216 GGVFGSLMGTPIINPPQSAILGMHGIFER--PIALNGQVVIRPMMYIALTYDHRLIDGRE 389
GG FG IINPPQSAIL + +R P +++GQ M ++ DHR+IDG
Sbjct: 1733 GGPFGIKQFCAIINPPQSAILAIGTAEKRVIPGSVDGQYEFGSFMSATMSCDHRVIDGAI 1792
Query: 390 AVLFLRKIKEGVEDPATIV 446
FL+ K +E+P +++
Sbjct: 1793 GAEFLKAFKGYIENPNSML 1811
>UniRef50_Q9XYS5 Cluster: Dihydrolipoyl dehydrogenase-binding
protein; n=2; Ascaris suum|Rep: Dihydrolipoyl
dehydrogenase-binding protein - Ascaris suum (Pig
roundworm) (Ascaris lumbricoides)
Length = 368
Score = 95.5 bits (227), Expect = 1e-18
Identities = 55/138 (39%), Positives = 78/138 (56%), Gaps = 1/138 (0%)
Frame = +3
Query: 39 VDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNG 218
VDISVAVATP GL+ P++ + + I + LA+KAR KLT+EE GGTFT+SN
Sbjct: 222 VDISVAVATPAGLITPIVFKADTLGVSQIGAKVRELAKKARANKLTLEEFQGGTFTVSNL 281
Query: 219 GVFGSLMG-TPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLIDGREAV 395
G++GS+ T IINPPQ+AI+ + G + L + + L +D R I +A
Sbjct: 282 GMYGSISHFTAIINPPQAAIMAIGGGIDE---LETDLSSTNRFQVTLCFDGRAITVPDAH 338
Query: 396 LFLRKIKEGVEDPATIVA 449
FL ++P +VA
Sbjct: 339 RFLEHFAMTFKEPDLMVA 356
>UniRef50_P12695 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex, mitochondrial precursor; n=3;
Saccharomycetales|Rep: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex, mitochondrial precursor - Saccharomyces
cerevisiae (Baker's yeast)
Length = 482
Score = 95.5 bits (227), Expect = 1e-18
Identities = 59/147 (40%), Positives = 84/147 (57%), Gaps = 7/147 (4%)
Frame = +3
Query: 15 NEIIYRDY--VDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEM 188
NE + R + VD+SVAVATP GL+ P+++N + + I I L ++AR KL EE
Sbjct: 332 NENVIRKFKNVDVSVAVATPTGLLTPIVKNCEAKGLSQISNEIKELVKRARINKLAPEEF 391
Query: 189 DGGTFTISNGGVFGSL-MGTPIINPPQSAILGMHGI----FERPIALNGQVVIRPMMYIA 353
GGT ISN G+ ++ M T IINPPQS IL + + E A NG + I
Sbjct: 392 QGGTICISNMGMNNAVNMFTSIINPPQSTILAIATVERVAVEDAAAENG-FSFDNQVTIT 450
Query: 354 LTYDHRLIDGREAVLFLRKIKEGVEDP 434
T+DHR IDG + F++++K +E+P
Sbjct: 451 GTFDHRTIDGAKGAEFMKELKTVIENP 477
>UniRef50_A3SYT7 Cluster: Acetoin dehydrogenase E2 component; n=2;
Sulfitobacter|Rep: Acetoin dehydrogenase E2 component -
Sulfitobacter sp. NAS-14.1
Length = 223
Score = 95.1 bits (226), Expect = 2e-18
Identities = 55/143 (38%), Positives = 81/143 (56%), Gaps = 2/143 (1%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPKGLVV-PVIRNVQNMTYADIELTIAGLAEKARTGKLTIE 182
+E E+ D VD+SVA+A P L+V P + M ++ LA +A+ KLT+
Sbjct: 77 VEGREVHLSDAVDLSVAIALPGNLLVAPAMFGADAMDVTELRAARQDLAARAKVNKLTVT 136
Query: 183 EMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPI-ALNGQVVIRPMMYIALT 359
EM GGTFT+SN G+ TPIIN Q ILG+ + +R + +G + +RP + ++LT
Sbjct: 137 EMTGGTFTVSNLGLTRVEHFTPIINAGQICILGIGRMTDRAVRGADGGIELRPHVGLSLT 196
Query: 360 YDHRLIDGREAVLFLRKIKEGVE 428
+DHR +DG A L I E +E
Sbjct: 197 FDHRALDGAPAGDLLTSICEEIE 219
>UniRef50_Q1EGH5 Cluster: Pyruvate dehydrogenase E2 subunit; n=3;
Nyctotherus ovalis|Rep: Pyruvate dehydrogenase E2
subunit - Nyctotherus ovalis
Length = 485
Score = 94.7 bits (225), Expect = 2e-18
Identities = 51/147 (34%), Positives = 83/147 (56%), Gaps = 7/147 (4%)
Frame = +3
Query: 27 YRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFT 206
Y+D VD+SVAV TP GL+ P++ + I L KA+ G L E+ GGTFT
Sbjct: 339 YKD-VDMSVAVQTPNGLITPIVPRANLKGFEQIAKITKELIAKAKDGTLKPEQFIGGTFT 397
Query: 207 ISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIA-------LNGQVVIRPMMYIALTYD 365
ISN G++G PI+NPPQ+ ILG+ + ++ + + + I M ++L+ D
Sbjct: 398 ISNAGMYGISQLIPIVNPPQACILGVSAVEKKVVVDEAKNEHMPAPLRIASKMTVSLSCD 457
Query: 366 HRLIDGREAVLFLRKIKEGVEDPATIV 446
HR++DG + ++ K+ +E+PA ++
Sbjct: 458 HRVVDGAGGAEWTQEFKKLIENPALMM 484
>UniRef50_UPI00015A4520 Cluster: UPI00015A4520 related cluster; n=3;
Danio rerio|Rep: UPI00015A4520 UniRef100 entry - Danio
rerio
Length = 494
Score = 94.3 bits (224), Expect = 3e-18
Identities = 50/134 (37%), Positives = 78/134 (58%), Gaps = 1/134 (0%)
Frame = +3
Query: 36 YVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISN 215
++ IS+AVAT +GL+ P+IR+ + +I T LA+KAR GKL EE GG+F++SN
Sbjct: 354 FIHISMAVATDRGLITPIIRDAADKGLQEISSTAKALAQKARDGKLLPEEYQGGSFSVSN 413
Query: 216 GGVFGSLMGTPIINPPQSAILGMHGI-FERPIALNGQVVIRPMMYIALTYDHRLIDGREA 392
G+FG + +INPPQ+ IL + G E ++ + + + + L+ D RL+D A
Sbjct: 414 LGMFGISEFSAVINPPQACILAVGGSRTELSLSAEDTLQTQHTLTVTLSSDARLVDDELA 473
Query: 393 VLFLRKIKEGVEDP 434
FL + +E P
Sbjct: 474 SRFLETFRSNLERP 487
>UniRef50_Q8EJN8 Cluster: Pyruvate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase; n=103;
Proteobacteria|Rep: Pyruvate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase -
Shewanella oneidensis
Length = 677
Score = 94.3 bits (224), Expect = 3e-18
Identities = 53/142 (37%), Positives = 79/142 (55%)
Frame = +3
Query: 21 IIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGT 200
+I + Y I VAV TP GLVVPV+R+V ++ +A ++ +AR GKL +M G
Sbjct: 535 LIQKKYFHIGVAVDTPNGLVVPVVRDVDKKGIIELSRELADISIRARDGKLKSADMQGSC 594
Query: 201 FTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLID 380
FTIS+ G G TPI+N P AILG+ +P + + M+ ++L+YDHR+ID
Sbjct: 595 FTISSLGGIGGTAFTPIVNYPDVAILGVSKSEIKPKWNGKEFEPKLMLPLSLSYDHRVID 654
Query: 381 GREAVLFLRKIKEGVEDPATIV 446
G A F + + D T++
Sbjct: 655 GAMAARFSVTLSGILSDIRTLI 676
>UniRef50_P36413 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex, mitochondrial precursor; n=2; Dictyostelium
discoideum|Rep: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex, mitochondrial precursor - Dictyostelium
discoideum (Slime mold)
Length = 592
Score = 94.3 bits (224), Expect = 3e-18
Identities = 52/141 (36%), Positives = 81/141 (57%), Gaps = 5/141 (3%)
Frame = +3
Query: 39 VDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNG 218
+DI+VAV TP+GL P++R V I ++ LAEKA+ GKL E + GTFTISN
Sbjct: 453 IDINVAVNTPQGLFTPIVRGVDMKGLNSISTSVKQLAEKAQNGKLHPSEFESGTFTISNL 512
Query: 219 GVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRP-----MMYIALTYDHRLIDG 383
G+ G +INPPQ+AIL + + ++ ++ P ++ + L+ DHR+IDG
Sbjct: 513 GMLGIKQFAAVINPPQAAILAL--VPQKLVSFLSNKPDSPYETATILSVTLSCDHRVIDG 570
Query: 384 REAVLFLRKIKEGVEDPATIV 446
+L+ K+ VE+P ++
Sbjct: 571 AVGAEWLKSFKDYVENPIKLI 591
>UniRef50_UPI0000E4A22B Cluster: PREDICTED: similar to pyruvate
dehydrogenase complex, component X; n=4;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
pyruvate dehydrogenase complex, component X -
Strongylocentrotus purpuratus
Length = 482
Score = 93.5 bits (222), Expect = 5e-18
Identities = 48/132 (36%), Positives = 75/132 (56%)
Frame = +3
Query: 39 VDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNG 218
+DISVAVAT GL+ P+++ +I + LA +AR KL ++E GG+F+ISN
Sbjct: 348 IDISVAVATDGGLITPIVKGADAKGLMEISANVRDLATRARANKLKLDEFQGGSFSISNL 407
Query: 219 GVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLIDGREAVL 398
G+FG + +INPPQS I+ + G +A+ M + ++ D R++DG A
Sbjct: 408 GMFGISEFSAVINPPQSCIMAIGG---SQLAIGKDRKPLTYMTVTMSSDARVVDGALASR 464
Query: 399 FLRKIKEGVEDP 434
FL+ K+ +E P
Sbjct: 465 FLKTFKQNIESP 476
>UniRef50_Q5WE92 Cluster: Acetoin dehydrogenase E2 component; n=1;
Bacillus clausii KSM-K16|Rep: Acetoin dehydrogenase E2
component - Bacillus clausii (strain KSM-K16)
Length = 410
Score = 93.5 bits (222), Expect = 5e-18
Identities = 52/148 (35%), Positives = 86/148 (58%), Gaps = 2/148 (1%)
Frame = +3
Query: 9 EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEM 188
E ++ + V + +A + GLVVPVIRN +++ + I +A AR+G+ +E+
Sbjct: 263 ENGQLKEFENVHLGIATSLDDGLVVPVIRNADHLSIGQLATKIEKIAANARSGQSNPDEL 322
Query: 189 DGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIAL--NGQVVIRPMMYIALTY 362
G TFTI+N G TPI+NP ++ ILG+ G ++ +AL +GQV M +LT+
Sbjct: 323 SGSTFTITNLGASSIEYFTPILNPAETGILGV-GSLQQELALSEDGQVEPVQKMPFSLTF 381
Query: 363 DHRLIDGREAVLFLRKIKEGVEDPATIV 446
DH+++DG A FL + + VE+P ++
Sbjct: 382 DHQIVDGVLAAQFLDAVVKYVENPHLLI 409
>UniRef50_P20285 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex, mitochondrial precursor; n=40; Eukaryota|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex, mitochondrial
precursor - Neurospora crassa
Length = 458
Score = 93.5 bits (222), Expect = 5e-18
Identities = 49/142 (34%), Positives = 84/142 (59%), Gaps = 6/142 (4%)
Frame = +3
Query: 39 VDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNG 218
VD+SVAVATP GL+ P+++ V+ I + LA+KAR GKL EE GG+ +ISN
Sbjct: 316 VDVSVAVATPNGLITPIVKGVEGKGLESISAAVKELAKKARDGKLKPEEYQGGSISISNM 375
Query: 219 GVFGSLMG-TPIINPPQSAILGMHGIFERPIALNGQ-----VVIRPMMYIALTYDHRLID 380
G+ ++ T IINPPQ+AIL + + + + + V + + ++DH+++D
Sbjct: 376 GMNPAVQSFTAIINPPQAAILAVGAPQKVAVPVENEDGTTGVSWDEQIIVTASFDHKVVD 435
Query: 381 GREAVLFLRKIKEGVEDPATIV 446
G ++R++K+ +E+P ++
Sbjct: 436 GAVGAEWIRELKKVIENPLELL 457
>UniRef50_Q057U1 Cluster: Pyruvate dehydrogenase E2 component; n=1;
Buchnera aphidicola str. Cc (Cinara cedri)|Rep: Pyruvate
dehydrogenase E2 component - Buchnera aphidicola subsp.
Cinara cedri
Length = 417
Score = 92.7 bits (220), Expect = 8e-18
Identities = 50/141 (35%), Positives = 84/141 (59%)
Frame = +3
Query: 9 EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEM 188
++N II +D ++I +AV T GL+VPV+++++N T +I I + K + +L EM
Sbjct: 272 KKNIIIKKD-INIGIAVDTHDGLLVPVLKSLKNKTIYEISNNIFNVVTKTKNNQLCTSEM 330
Query: 189 DGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDH 368
G+FTIS+ G G + TPIIN P+ ILG+ +P+ + R ++ +++YDH
Sbjct: 331 TDGSFTISSLGGIGGIGFTPIINAPEVCILGISKADIKPVWNKKKFYPRLILPFSISYDH 390
Query: 369 RLIDGREAVLFLRKIKEGVED 431
R+IDG + V F +K+ + D
Sbjct: 391 RVIDGADGVRFTTFLKDILSD 411
>UniRef50_A4SZ52 Cluster: Catalytic domain of components of various
dehydrogenase complexes precursor; n=1; Polynucleobacter
sp. QLW-P1DMWA-1|Rep: Catalytic domain of components of
various dehydrogenase complexes precursor -
Polynucleobacter sp. QLW-P1DMWA-1
Length = 472
Score = 92.7 bits (220), Expect = 8e-18
Identities = 54/142 (38%), Positives = 78/142 (54%)
Frame = +3
Query: 6 IEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEE 185
++ E+I + Y I AV T GLVVPVIRN +I A LA+ AR GKL E+
Sbjct: 325 LDGEELILKKYCHIGFAVDTNIGLVVPVIRNADQKGILEIAKETAELAQLARDGKLKPEQ 384
Query: 186 MDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYD 365
M G +FTIS+ G G PIIN P+ AIL ++ +P+ + + R + +++T D
Sbjct: 385 MQGASFTISSLGGIGGTYCAPIINAPEVAILAVNKSAIKPVWDGAEFIPRLICPLSMTAD 444
Query: 366 HRLIDGREAVLFLRKIKEGVED 431
HR+IDG A F + + + D
Sbjct: 445 HRVIDGALATHFTTYLAQLLAD 466
>UniRef50_Q15U82 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=3; Gammaproteobacteria|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Pseudoalteromonas atlantica (strain T6c /
BAA-1087)
Length = 555
Score = 92.3 bits (219), Expect = 1e-17
Identities = 54/147 (36%), Positives = 83/147 (56%), Gaps = 1/147 (0%)
Frame = +3
Query: 18 EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGG 197
++ Y + +I AV GL+VP I+ VQ+M+ DI + L E+AR G+L ++ GG
Sbjct: 408 QLTYFNEHNIGFAVDGKLGLMVPNIKGVQDMSIFDIAKRASELIEQAREGRLRTADISGG 467
Query: 198 TFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERP-IALNGQVVIRPMMYIALTYDHRL 374
T +ISN GV G + TP+IN P++AI+ + I P N QV +M+++ + DHR+
Sbjct: 468 TISISNIGVLGGTVATPVINHPEAAIVALGKIQRLPRFDENDQVRAVNIMHVSWSGDHRI 527
Query: 375 IDGREAVLFLRKIKEGVEDPATIVAGL 455
IDG V F K +E P ++ L
Sbjct: 528 IDGATMVRFNNLWKSYIEQPIKMLGTL 554
>UniRef50_A5CVP1 Cluster: Pyruvate dehydrogenase complex E2
component; n=3; Bacteria|Rep: Pyruvate dehydrogenase
complex E2 component - Vesicomyosocius okutanii subsp.
Calyptogena okutanii (strain HA)
Length = 507
Score = 92.3 bits (219), Expect = 1e-17
Identities = 46/131 (35%), Positives = 76/131 (58%)
Frame = +3
Query: 21 IIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGT 200
+I + Y ++ +A+ TPKGL+VPVIR+V+ + D+ + ++ AR KL +M G
Sbjct: 367 LIIKKYFNLGIAMDTPKGLIVPVIRDVEKKSLTDLAKELFETSKNARENKLKPADMQGSG 426
Query: 201 FTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLID 380
TIS+ G G TPI+N P+ AILG+ + +P + + +AL+YDHR+ID
Sbjct: 427 LTISSLGGIGGTQFTPIVNAPEVAILGISRSYFKPTWDGENFIPTLTLPLALSYDHRVID 486
Query: 381 GREAVLFLRKI 413
G + F+ ++
Sbjct: 487 GAQGGRFMAEL 497
>UniRef50_Q6C806 Cluster: Similar to tr|Q9VXY3 Drosophila
melanogaster CG5599 protein; n=1; Yarrowia
lipolytica|Rep: Similar to tr|Q9VXY3 Drosophila
melanogaster CG5599 protein - Yarrowia lipolytica
(Candida lipolytica)
Length = 466
Score = 91.5 bits (217), Expect = 2e-17
Identities = 52/146 (35%), Positives = 81/146 (55%), Gaps = 1/146 (0%)
Frame = +3
Query: 21 IIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGT 200
++ RDY +IS+A+ TP GL+VP I+NVQ+ T +I + L E GKL+ +++ GGT
Sbjct: 320 VLMRDYHNISIAMDTPNGLLVPTIKNVQDKTIVEIAADLQRLQELGMAGKLSRDDLTGGT 379
Query: 201 FTISNGGVFGSLMGTPIINPPQSAILGMHGIFERP-IALNGQVVIRPMMYIALTYDHRLI 377
+ISN G G +P+I Q AI+G+ + P G +V ++ + + DHR++
Sbjct: 380 ISISNIGNVGGTYLSPVIVSEQVAIVGLGKARKLPRYNSQGDIVPEQIINASWSGDHRVL 439
Query: 378 DGREAVLFLRKIKEGVEDPATIVAGL 455
DG L K K V DP ++ L
Sbjct: 440 DGMTMALMADKWKAYVVDPKAMLLQL 465
>UniRef50_Q4WQ92 Cluster: 2-oxo acid dehydrogenases acyltransferase,
putative; n=1; Aspergillus fumigatus|Rep: 2-oxo acid
dehydrogenases acyltransferase, putative - Aspergillus
fumigatus (Sartorya fumigata)
Length = 460
Score = 91.5 bits (217), Expect = 2e-17
Identities = 52/150 (34%), Positives = 83/150 (55%), Gaps = 1/150 (0%)
Frame = +3
Query: 9 EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEM 188
E+ ++I R +I VA+ TP+GL+VP I++V N T +I I L+ + GKLT ++
Sbjct: 310 EKPKLIMRPKHNIGVALDTPQGLIVPNIKDVANRTIMEIAAEIKRLSALGKEGKLTPADL 369
Query: 189 DGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALN-GQVVIRPMMYIALTYD 365
GGT T+SN G G P+I P + AILG+ P+ + GQV ++ + + D
Sbjct: 370 SGGTITVSNIGNIGGTYVGPVIVPTEVAILGVGKSRTVPVFDDAGQVTKGELVNFSWSAD 429
Query: 366 HRLIDGREAVLFLRKIKEGVEDPATIVAGL 455
HR++DG K++E +E P ++ L
Sbjct: 430 HRVVDGATMARMANKVREFIESPELMLLNL 459
>UniRef50_UPI000038D51F Cluster: COG0508: Pyruvate/2-oxoglutarate
dehydrogenase complex, dihydrolipoamide acyltransferase
(E2) component, and related enzymes; n=1; Nostoc
punctiforme PCC 73102|Rep: COG0508:
Pyruvate/2-oxoglutarate dehydrogenase complex,
dihydrolipoamide acyltransferase (E2) component, and
related enzymes - Nostoc punctiforme PCC 73102
Length = 367
Score = 91.1 bits (216), Expect = 3e-17
Identities = 55/147 (37%), Positives = 82/147 (55%), Gaps = 2/147 (1%)
Frame = +3
Query: 3 VIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIE 182
+I++N + + +I V + KGL +PVI+NV ++ ADI + KA G+ E
Sbjct: 221 LIDDNRFMPGEVANIGVTLDLGKGLFIPVIKNVGEISLADIANKLMEFRLKAMRGQFNEE 280
Query: 183 EMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYI--AL 356
E++ G ++S SL+ PII P QS +L + GI E + L + ++ YI L
Sbjct: 281 ELNQGNISLSINMDKDSLVTIPIILPSQSCMLSLGGIQEE-LYLGSEQNVKNRSYINLGL 339
Query: 357 TYDHRLIDGREAVLFLRKIKEGVEDPA 437
YDHR+I+GREA FL KIK VE P+
Sbjct: 340 AYDHRVINGREAAQFLTKIKTKVEQPS 366
>UniRef50_A0NRH8 Cluster: Branched-chain alpha-keto acid
dehydrogenase E2 subunit; n=1; Stappia aggregata IAM
12614|Rep: Branched-chain alpha-keto acid dehydrogenase
E2 subunit - Stappia aggregata IAM 12614
Length = 301
Score = 90.6 bits (215), Expect = 3e-17
Identities = 52/128 (40%), Positives = 72/128 (56%)
Frame = +3
Query: 21 IIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGT 200
+ +DYV + VAV T GL+VPVIR+V I IA LA +A K+ +EM G +
Sbjct: 159 LFLKDYVHLGVAVDTAHGLMVPVIRDVDRKGLWQIAAEIADLASRALERKVRPDEMGGAS 218
Query: 201 FTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLID 380
TI+N G G TPI+NPP+ AILG+ P+ M+ + L+YDHR+I+
Sbjct: 219 MTITNLGGIGGTAFTPIVNPPEVAILGITRTELAPVWDGETFQPVQMVPLDLSYDHRVIN 278
Query: 381 GREAVLFL 404
G +A FL
Sbjct: 279 GADAARFL 286
>UniRef50_Q8RWN9 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component 2 of pyruvate dehydrogenase
complex, mitochondrial precursor; n=14; cellular
organisms|Rep: Dihydrolipoyllysine-residue
acetyltransferase component 2 of pyruvate dehydrogenase
complex, mitochondrial precursor - Arabidopsis thaliana
(Mouse-ear cress)
Length = 539
Score = 90.6 bits (215), Expect = 3e-17
Identities = 52/139 (37%), Positives = 79/139 (56%), Gaps = 3/139 (2%)
Frame = +3
Query: 39 VDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISN- 215
V+I+VAV T GL VPV+++ + I + LA+KA+ L E+ +GGTFT+SN
Sbjct: 400 VNINVAVQTENGLYVPVVKDADKKGLSTIGEEVRFLAQKAKENSLKPEDYEGGTFTVSNL 459
Query: 216 GGVFGSLMGTPIINPPQSAILGMHGIFERPIALNG--QVVIRPMMYIALTYDHRLIDGRE 389
GG FG +INPPQ+AIL + +R + G Q + M + L+ DHR+IDG
Sbjct: 460 GGPFGIKQFCAVINPPQAAILAIGSAEKRVVPGTGPDQYNVASYMSVTLSCDHRVIDGAI 519
Query: 390 AVLFLRKIKEGVEDPATIV 446
+L+ K +E P +++
Sbjct: 520 GAEWLKAFKGYIETPESML 538
>UniRef50_A0Z3Y6 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex, dihydrolipoamide acyltransferase (E2)
component, and related enzyme; n=1; marine gamma
proteobacterium HTCC2080|Rep: Pyruvate/2-oxoglutarate
dehydrogenase complex, dihydrolipoamide acyltransferase
(E2) component, and related enzyme - marine gamma
proteobacterium HTCC2080
Length = 388
Score = 89.8 bits (213), Expect = 6e-17
Identities = 46/129 (35%), Positives = 75/129 (58%)
Frame = +3
Query: 42 DISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNGG 221
+I+VA+AT GL I V+ + A++ LAEKAR+ LT E++ GG+FT+SN G
Sbjct: 258 NIAVAIATDDGLYPATIPGVEAKSPAEVAQATGALAEKARSNSLTKEDISGGSFTVSNLG 317
Query: 222 VFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLIDGREAVLF 401
++G T IINPP AIL + + + +G+ I ++ L+ DHR+IDG F
Sbjct: 318 MYGISEFTAIINPPMGAILALGKAEPKVVVKDGEQSIATVLTATLSCDHRVIDGAVGAQF 377
Query: 402 LRKIKEGVE 428
+ +++ ++
Sbjct: 378 MAALRDVID 386
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 680,304,276
Number of Sequences: 1657284
Number of extensions: 13720982
Number of successful extensions: 37650
Number of sequences better than 10.0: 347
Number of HSP's better than 10.0 without gapping: 36029
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 37457
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 59677054775
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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