Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmte2i16
(730 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AF045458-1|AAC32326.1| 1050|Homo sapiens serine/threonine kinase... 232 8e-61
AB018265-1|BAA34442.2| 1066|Homo sapiens KIAA0722 protein protein. 232 8e-61
BC034988-1|AAH34988.1| 1036|Homo sapiens ULK2 protein protein. 232 1e-60
AB014523-1|BAA31598.2| 1100|Homo sapiens KIAA0623 protein protein. 232 1e-60
BC056423-1|AAH56423.1| 214|Homo sapiens ULK3 protein protein. 136 1e-31
BC036117-1|AAH36117.1| 214|Homo sapiens ULK3 protein protein. 136 1e-31
BC117183-1|AAI17184.1| 926|Homo sapiens SNF1-like kinase 2 prot... 113 6e-25
BC113459-1|AAI13460.1| 926|Homo sapiens SNF1-like kinase 2 prot... 113 6e-25
AB084424-1|BAB91442.1| 346|Homo sapiens KIAA0781 protein protein. 113 6e-25
AB018324-1|BAA34501.3| 950|Homo sapiens KIAA0781 protein protein. 113 6e-25
X97630-1|CAA66229.1| 745|Homo sapiens serine/threonine protein ... 110 6e-24
BT007342-1|AAP36006.1| 755|Homo sapiens MAP/microtubule affinit... 110 6e-24
BC084540-1|AAH84540.1| 724|Homo sapiens MAP/microtubule affinit... 110 6e-24
BC026158-1|AAH26158.1| 1315|Homo sapiens serine/threonine kinase... 110 6e-24
BC008771-1|AAH08771.2| 778|Homo sapiens MARK2 protein protein. 110 6e-24
AF387638-1|AAK82368.1| 691|Homo sapiens Ser/Thr protein kinase ... 110 6e-24
AF200815-1|AAF97028.1| 1315|Homo sapiens FUSED serine/threonine ... 110 6e-24
AB188493-1|BAD37141.1| 719|Homo sapiens serine/threonine kinase... 110 6e-24
AB051552-1|BAB21856.1| 608|Homo sapiens KIAA1765 protein protein. 110 6e-24
AB033104-1|BAA86592.1| 1311|Homo sapiens KIAA1278 protein protein. 110 6e-24
BC114478-1|AAI14479.1| 795|Homo sapiens MARK1 protein protein. 109 1e-23
BC113869-1|AAI13870.1| 795|Homo sapiens MARK1 protein protein. 109 1e-23
AL592406-3|CAH72463.1| 795|Homo sapiens MAP/microtubule affinit... 109 1e-23
AF154845-1|AAF72103.1| 795|Homo sapiens MARK protein. 109 1e-23
CR456418-1|CAG30304.1| 586|Homo sapiens CHEK2 protein. 108 2e-23
BC035745-1|AAH35745.1| 385|Homo sapiens calcium/calmodulin-depe... 108 2e-23
BC004207-1|AAH04207.1| 543|Homo sapiens CHK2 checkpoint homolog... 108 2e-23
AY800241-1|AAV41895.1| 543|Homo sapiens CHK2 checkpoint homolog... 108 2e-23
AY551303-1|AAS58464.1| 452|Homo sapiens protein kinase Chk2 tra... 108 2e-23
AY551297-1|AAS58458.1| 586|Homo sapiens protein kinase Chk2 tra... 108 2e-23
AL731559-2|CAI14675.1| 385|Homo sapiens calcium/calmodulin-depe... 108 2e-23
AL731559-1|CAI14674.1| 357|Homo sapiens calcium/calmodulin-depe... 108 2e-23
AL512783-2|CAH74036.1| 385|Homo sapiens calcium/calmodulin-depe... 108 2e-23
AL512783-1|CAH74035.1| 357|Homo sapiens calcium/calmodulin-depe... 108 2e-23
AL512284-2|CAH71694.1| 385|Homo sapiens calcium/calmodulin-depe... 108 2e-23
AL512284-1|CAH71693.1| 357|Homo sapiens calcium/calmodulin-depe... 108 2e-23
AL391314-2|CAI14410.1| 385|Homo sapiens calcium/calmodulin-depe... 108 2e-23
AL391314-1|CAI14409.1| 357|Homo sapiens calcium/calmodulin-depe... 108 2e-23
AL121825-1|CAH73823.1| 543|Homo sapiens CHK2 checkpoint homolog... 108 2e-23
AL117330-1|CAH73875.1| 543|Homo sapiens CHK2 checkpoint homolog... 108 2e-23
AJ131197-1|CAA10319.1| 543|Homo sapiens protein kinase protein. 108 2e-23
AF286366-1|AAG00534.1| 357|Homo sapiens CamKI-like protein kina... 108 2e-23
AF174135-1|AAD48504.1| 543|Homo sapiens protein kinase CHK2 pro... 108 2e-23
AF096279-1|AAD11784.1| 543|Homo sapiens HuCds1 kinase protein. 108 2e-23
AF086904-1|AAC83693.1| 543|Homo sapiens protein kinase Chk2 pro... 108 2e-23
AB081726-1|BAC19846.1| 385|Homo sapiens CaM-kinase I delta prot... 108 2e-23
BC017306-1|AAH17306.1| 628|Homo sapiens NUAK family, SNF1-like ... 108 2e-23
AK074830-1|BAC11234.1| 628|Homo sapiens protein ( Homo sapiens ... 108 2e-23
L41816-1|AAA99458.1| 370|Homo sapiens cam kinase I protein. 107 3e-23
BC106755-1|AAI06756.1| 370|Homo sapiens calcium/calmodulin-depe... 107 3e-23
BC106754-1|AAI06755.1| 370|Homo sapiens calcium/calmodulin-depe... 107 3e-23
AF217975-1|AAG17218.1| 322|Homo sapiens unknown protein. 107 5e-23
L24959-1|AAA18251.1| 473|Homo sapiens calcium/calmodulin depend... 106 7e-23
L17000-1|AAA35639.1| 473|Homo sapiens calcium/calmodulin-depend... 106 7e-23
D30742-1|BAA06403.1| 473|Homo sapiens calmodulin-dependent prot... 106 7e-23
BC126432-1|AAI26433.1| 454|Homo sapiens death-associated protei... 106 7e-23
BC126430-1|AAI26431.1| 454|Homo sapiens death-associated protei... 106 7e-23
BC037303-1|AAH37303.1| 550|Homo sapiens PRKAA1 protein protein. 106 7e-23
BC025687-1|AAH25687.1| 473|Homo sapiens calcium/calmodulin-depe... 106 7e-23
BC016695-1|AAH16695.2| 503|Homo sapiens CAMK4 protein protein. 106 7e-23
BC012622-1|AAH12622.1| 207|Homo sapiens PRKAA1 protein protein. 106 7e-23
AB022341-1|BAA81746.1| 454|Homo sapiens ZIP kinase protein. 106 7e-23
AB022017-1|BAA36547.1| 550|Homo sapiens AMP-activated protein k... 106 7e-23
AB007144-1|BAA24955.1| 454|Homo sapiens ZIP-kinase protein. 106 7e-23
U64205-1|AAC15093.1| 729|Homo sapiens Cdc25C associated protein... 106 9e-23
BC038504-1|AAH38504.1| 783|Homo sapiens SNF1-like kinase protein. 106 9e-23
BC024773-1|AAH24773.1| 729|Homo sapiens MAP/microtubule affinit... 106 9e-23
AK131076-1|BAC85126.1| 764|Homo sapiens FLJ00263 protein protein. 106 9e-23
AF387637-1|AAK82367.1| 744|Homo sapiens Ser/Thr protein kinase ... 106 9e-23
AB047786-1|BAD74070.1| 783|Homo sapiens serine/threonine protei... 106 9e-23
M80359-1|AAA59991.1| 713|Homo sapiens protein p78 protein. 105 2e-22
AF465413-1|AAL69982.1| 753|Homo sapiens MAP/microtubule affinit... 105 2e-22
BC015472-1|AAH15472.1| 363|Homo sapiens PRKD2 protein protein. 104 3e-22
AK075266-1|BAC11508.1| 721|Homo sapiens protein ( Homo sapiens ... 104 3e-22
AK074673-1|BAC11127.1| 721|Homo sapiens protein ( Homo sapiens ... 104 3e-22
AF309082-1|AAK01149.1| 878|Homo sapiens protein kinase D2 protein. 104 3e-22
BC031231-1|AAH31231.1| 514|Homo sapiens serine/threonine kinase... 104 4e-22
AK093251-1|BAC04109.1| 514|Homo sapiens protein ( Homo sapiens ... 104 4e-22
AJ303380-1|CAC29064.1| 514|Homo sapiens serine/threonine kinase... 104 4e-22
U22456-1|AAA64850.1| 174|Homo sapiens AMP-activated protein kin... 103 5e-22
AB011109-1|BAA25463.2| 698|Homo sapiens KIAA0537 protein protein. 103 5e-22
AC007390-1|AAY14817.1| 890|Homo sapiens unknown protein. 103 7e-22
AB015982-1|BAA36514.1| 890|Homo sapiens serine/threonine kinase... 103 7e-22
AY120867-1|AAM55491.1| 752|Homo sapiens MAP/microtubule affinit... 103 9e-22
AY057448-1|AAL23683.1| 752|Homo sapiens MARK4 serine/threonine ... 103 9e-22
AK075272-1|BAC11510.1| 752|Homo sapiens protein ( Homo sapiens ... 103 9e-22
AB058763-1|BAB47489.1| 689|Homo sapiens KIAA1860 protein protein. 103 9e-22
BC114506-1|AAI14507.1| 370|Homo sapiens death-associated protei... 102 2e-21
AF052941-1|AAC35001.1| 370|Homo sapiens DAP-kinase related prot... 102 2e-21
AB018001-1|BAA88063.1| 370|Homo sapiens Death-associated protei... 102 2e-21
U06454-1|AAA64745.1| 552|Homo sapiens AMP-activated protein kin... 101 2e-21
EF056019-1|ABK30810.1| 552|Homo sapiens AMP-activated alpha 2 s... 101 2e-21
BC069823-1|AAH69823.1| 552|Homo sapiens AMP-activated protein k... 101 2e-21
BC069740-1|AAH69740.1| 552|Homo sapiens AMP-activated protein k... 101 2e-21
BC069680-1|AAH69680.1| 552|Homo sapiens protein kinase, AMP-act... 101 2e-21
BC036422-1|AAH36422.1| 436|Homo sapiens hypothetical protein MG... 101 2e-21
AP001751-1|BAA95536.1| 786|Homo sapiens SNF1LK protein. 101 2e-21
AL035705-2|CAC17574.2| 552|Homo sapiens protein kinase, AMP-act... 101 2e-21
BC032787-1|AAH32787.1| 476|Homo sapiens calcium/calmodulin-depe... 101 3e-21
AY212935-1|AAP29964.1| 460|Homo sapiens CLICK III protein. 101 3e-21
AL049688-1|CAB41259.1| 481|Homo sapiens hypothetical protein pr... 101 3e-21
AL023754-3|CAI19991.1| 476|Homo sapiens calcium/calmodulin-depe... 101 3e-21
AF428261-1|AAL28100.1| 476|Homo sapiens calcium/calmodulin-depe... 101 3e-21
X75756-1|CAA53384.1| 912|Homo sapiens protein kinase C mu protein. 101 3e-21
DQ485452-1|ABE96833.1| 914|Homo sapiens protein kinase D1 protein. 101 3e-21
AL390029-2|CAI15721.1| 740|Homo sapiens doublecortin and CaM ki... 100 5e-21
AL390029-1|CAI15720.1| 729|Homo sapiens doublecortin and CaM ki... 100 5e-21
AL160392-2|CAH70261.1| 740|Homo sapiens doublecortin and CaM ki... 100 5e-21
AL160392-1|CAH70262.1| 729|Homo sapiens doublecortin and CaM ki... 100 5e-21
AL157760-4|CAH70170.1| 433|Homo sapiens doublecortin and CaM ki... 100 5e-21
AL157760-2|CAH70167.1| 740|Homo sapiens doublecortin and CaM ki... 100 5e-21
AL157760-1|CAH70168.1| 729|Homo sapiens doublecortin and CaM ki... 100 5e-21
AL157694-2|CAH70656.1| 740|Homo sapiens doublecortin and CaM ki... 100 5e-21
AL157694-1|CAH70657.1| 729|Homo sapiens doublecortin and CaM ki... 100 5e-21
AB002367-1|BAA20824.2| 794|Homo sapiens KIAA0369 protein. 100 5e-21
X80590-1|CAA56681.1| 387|Homo sapiens phosphorylase kinase prot... 100 6e-21
BC128510-1|AAI28511.1| 1203|Homo sapiens KIAA0999 protein protein. 100 6e-21
BC074753-1|AAH74753.1| 387|Homo sapiens phosphorylase kinase, g... 100 6e-21
BC069754-1|AAH69754.1| 387|Homo sapiens phosphorylase kinase, g... 100 6e-21
BC069738-1|AAH69738.1| 387|Homo sapiens phosphorylase kinase, g... 100 6e-21
BC069679-1|AAH69679.1| 387|Homo sapiens phosphorylase kinase, g... 100 6e-21
BC051327-1|AAH51327.1| 387|Homo sapiens phosphorylase kinase, g... 100 6e-21
AF254253-1|AAL36972.1| 387|Homo sapiens phosphorylase kinase ga... 100 6e-21
AC092101-3|AAS07453.1| 387|Homo sapiens unknown protein. 100 6e-21
AB023216-1|BAA76843.2| 1371|Homo sapiens KIAA0999 protein protein. 100 6e-21
Z15108-1|CAA78813.1| 584|Homo sapiens protein kinase C zeta pro... 99 8e-21
BT007082-1|AAP35745.1| 592|Homo sapiens protein kinase C, zeta ... 99 8e-21
BC014270-1|AAH14270.1| 592|Homo sapiens protein kinase C, zeta ... 99 8e-21
BC008058-1|AAH08058.1| 592|Homo sapiens protein kinase C, zeta ... 99 8e-21
AL645703-1|CAI21535.1| 592|Homo sapiens protein kinase C, zeta ... 99 8e-21
AL590822-9|CAI12484.1| 592|Homo sapiens protein kinase C, zeta ... 99 8e-21
AL391845-5|CAI15438.1| 592|Homo sapiens protein kinase C, zeta ... 99 8e-21
AB088047-1|BAC03375.1| 752|Homo sapiens microtubule affinity-re... 99 8e-21
AB049127-1|BAB39380.1| 688|Homo sapiens MAP/microtubule affinit... 99 8e-21
L14283-1|AAA36488.1| 592|Homo sapiens protein kinase C zeta pro... 100 1e-20
Y11950-1|CAA72694.1| 406|Homo sapiens phosphorylase kinase gamm... 99 1e-20
M31606-1|AAA36442.1| 406|Homo sapiens phosphorylase kinase prot... 99 1e-20
BC002541-1|AAH02541.1| 406|Homo sapiens phosphorylase kinase, g... 99 1e-20
AY505124-1|AAS86442.1| 778|Homo sapiens protein kinase SAD-B pr... 99 1e-20
AY458602-1|AAS10354.1| 778|Homo sapiens SAD1 kinase protein. 99 1e-20
AK131198-1|BAD18393.1| 706|Homo sapiens protein ( Homo sapiens ... 99 1e-20
AF479827-1|AAL87698.1| 778|Homo sapiens protein kinase-like pro... 99 1e-20
AF479826-1|AAL87697.1| 794|Homo sapiens putative serine/threoni... 99 1e-20
Z84486-1|CAI21678.1| 526|Homo sapiens serum/glucocorticoid regu... 99 2e-20
Y10032-1|CAA71138.1| 431|Homo sapiens serine/threonine protein ... 99 2e-20
L33881-1|AAB17011.1| 587|Homo sapiens protein kinase C iota pro... 99 2e-20
L18964-1|AAA60171.1| 587|Homo sapiens protein kinase C iota pro... 99 2e-20
BC022016-1|AAH22016.3| 587|Homo sapiens protein kinase C, iota ... 99 2e-20
BC001263-1|AAH01263.1| 431|Homo sapiens serum/glucocorticoid re... 99 2e-20
AY505125-1|AAS86443.1| 696|Homo sapiens protein kinase SAD-A pr... 99 2e-20
AY166857-1|AAN87839.1| 668|Homo sapiens serine/threonine protei... 99 2e-20
AL355881-2|CAH72579.1| 526|Homo sapiens serum/glucocorticoid re... 99 2e-20
AL135839-4|CAI19721.1| 526|Homo sapiens serum/glucocorticoid re... 99 2e-20
AL135839-3|CAI19720.1| 445|Homo sapiens serum/glucocorticoid re... 99 2e-20
AL135839-2|CAI19719.1| 431|Homo sapiens serum/glucocorticoid re... 99 2e-20
AL135839-1|CAI19718.1| 421|Homo sapiens serum/glucocorticoid re... 99 2e-20
AJ000512-1|CAA04146.1| 431|Homo sapiens serine/threonine protei... 99 2e-20
AF533880-1|AAP97727.1| 674|Homo sapiens putative serine/threoni... 99 2e-20
AF533879-1|AAP97726.1| 736|Homo sapiens putative serine/threoni... 99 2e-20
AF533878-1|AAP97725.1| 674|Homo sapiens putative serine/threoni... 99 2e-20
AF533877-1|AAP97724.1| 674|Homo sapiens putative serine/threoni... 99 2e-20
AF533876-1|AAP97723.1| 668|Homo sapiens putative serine/threoni... 99 2e-20
AF153609-1|AAD41091.1| 431|Homo sapiens serine/threonine protei... 99 2e-20
X76104-1|CAA53712.1| 1431|Homo sapiens DAP-kinase protein. 98 3e-20
DQ436495-1|ABD96827.1| 1430|Homo sapiens death-associated protei... 98 3e-20
BT006935-1|AAP35581.1| 367|Homo sapiens death-associated protei... 98 3e-20
BC113660-1|AAI13661.1| 1430|Homo sapiens death-associated protei... 98 3e-20
AL591852-1|CAH71696.1| 1455|Homo sapiens death-associated protei... 98 3e-20
AL161787-1|CAH73544.1| 1455|Homo sapiens death-associated protei... 98 3e-20
AL160279-1|CAI16306.1| 1455|Homo sapiens death-associated protei... 98 3e-20
AB208871-1|BAD92108.1| 1433|Homo sapiens Hypothetical protein DK... 98 3e-20
Z92868-1|CAB07437.1| 686|Homo sapiens cGMP-dependent protein ki... 97 4e-20
Z92867-1|CAB07436.1| 671|Homo sapiens cGMP-dependent protein ki... 97 4e-20
Y13115-1|CAA73575.1| 970|Homo sapiens serine/threonine protein ... 97 4e-20
Y07512-1|CAA68810.1| 686|Homo sapiens protein ( Human mRNA for ... 97 4e-20
D45864-1|BAA08297.1| 671|Homo sapiens cGMP-dependent protein ki... 97 4e-20
BC127090-1|AAI27091.1| 686|Homo sapiens protein kinase, cGMP-de... 97 4e-20
BC036023-1|AAH36023.1| 970|Homo sapiens polo-like kinase 4 (Dro... 97 4e-20
AL928686-2|CAI40743.1| 686|Homo sapiens protein kinase, cGMP-de... 97 4e-20
AL928686-1|CAI40742.1| 659|Homo sapiens protein kinase, cGMP-de... 97 4e-20
AL731537-3|CAI17115.1| 686|Homo sapiens protein kinase, cGMP-de... 97 4e-20
AL731537-2|CAI17114.1| 659|Homo sapiens protein kinase, cGMP-de... 97 4e-20
AL391378-2|CAI39626.1| 686|Homo sapiens protein kinase, cGMP-de... 97 4e-20
AL391378-1|CAI39625.1| 659|Homo sapiens protein kinase, cGMP-de... 97 4e-20
AL157399-2|CAI41305.1| 686|Homo sapiens protein kinase, cGMP-de... 97 4e-20
AL157399-1|CAI41304.1| 659|Homo sapiens protein kinase, cGMP-de... 97 4e-20
AK131534-1|BAD18671.1| 766|Homo sapiens protein ( Homo sapiens ... 97 4e-20
AB006972-1|BAB69958.1| 970|Homo sapiens Sak protein. 97 4e-20
Z98752-7|CAI42315.1| 366|Homo sapiens serum/glucocorticoid regu... 97 6e-20
D43636-1|BAA07744.2| 766|Homo sapiens KIAA0096 protein. 96 1e-19
CR536566-1|CAG38803.1| 745|Homo sapiens RPS6KA6 protein. 96 1e-19
BC071567-1|AAH71567.1| 765|Homo sapiens SNRK protein protein. 96 1e-19
AL389887-1|CAC16111.2| 745|Homo sapiens ribosomal protein S6 ki... 96 1e-19
AL354653-1|CAD13486.2| 745|Homo sapiens ribosomal protein S6 ki... 96 1e-19
AK000231-1|BAA91023.1| 244|Homo sapiens protein ( Homo sapiens ... 96 1e-19
AF184965-1|AAF13190.1| 745|Homo sapiens ribosomal S6 kinase pro... 96 1e-19
Z98752-8|CAC18509.1| 367|Homo sapiens serum/glucocorticoid regu... 96 1e-19
Z98752-5|CAI42312.1| 427|Homo sapiens serum/glucocorticoid regu... 96 1e-19
Z98049-1|CAI20579.1| 733|Homo sapiens ribosomal protein S6 kina... 96 1e-19
X85106-1|CAA59427.1| 733|Homo sapiens ribosomal S6 kinase protein. 96 1e-19
BT020098-1|AAV38901.1| 367|Homo sapiens serum/glucocorticoid re... 96 1e-19
BC065511-1|AAH65511.1| 367|Homo sapiens SGK2 protein protein. 96 1e-19
BC014037-1|AAH14037.3| 367|Homo sapiens serum/glucocorticoid re... 96 1e-19
BC002363-1|AAH02363.1| 733|Homo sapiens ribosomal protein S6 ki... 96 1e-19
AY987010-1|AAX88805.1| 393|Homo sapiens serum/glucocorticoid re... 96 1e-19
AL022069-2|CAI19651.1| 733|Homo sapiens ribosomal protein S6 ki... 96 1e-19
AF186470-1|AAG17012.1| 427|Homo sapiens protein kinase protein. 96 1e-19
AF169034-1|AAF12757.2| 367|Homo sapiens protein kinase protein. 96 1e-19
AB209116-1|BAD92353.1| 806|Homo sapiens ribosomal protein S6 ki... 96 1e-19
EF560730-1|ABQ59040.1| 686|Homo sapiens PRKG1 protein protein. 95 2e-19
BC112101-1|AAI12102.1| 979|Homo sapiens NIMA related kinase 9 p... 95 2e-19
BC093881-1|AAH93881.1| 979|Homo sapiens NIMA (never in mitosis ... 95 2e-19
BC069655-1|AAH69655.1| 390|Homo sapiens PHKG1 protein protein. 95 2e-19
BC062616-1|AAH62616.1| 424|Homo sapiens protein serine kinase H... 95 2e-19
BC037268-1|AAH37268.1| 683|Homo sapiens protein kinase C, eta p... 95 2e-19
AY080896-1|AAL87410.1| 979|Homo sapiens NIMA-family kinase NERC... 95 2e-19
AY048580-1|AAL05428.1| 979|Homo sapiens NIMA-related kinase Nek... 95 2e-19
AJ272212-1|CAB91984.1| 424|Homo sapiens protein serine kinase p... 95 2e-19
AC007055-5|AAD31940.1| 312|Homo sapiens protein ( Homo sapiens ... 95 2e-19
AB082526-1|BAC02704.1| 1011|Homo sapiens KIAA1995 protein protein. 95 2e-19
Y16106-1|CAA76073.1| 734|Homo sapiens cGMP-dependant protein ki... 95 3e-19
X94612-1|CAA64318.1| 762|Homo sapiens Type II cGMP-dependent pr... 95 3e-19
U08316-1|AAA81952.1| 740|Homo sapiens insulin-stimulated protei... 95 3e-19
BC096303-1|AAH96303.1| 740|Homo sapiens ribosomal protein S6 ki... 95 3e-19
BC096302-1|AAH96302.1| 740|Homo sapiens ribosomal protein S6 ki... 95 3e-19
BC096301-1|AAH96301.1| 740|Homo sapiens ribosomal protein S6 ki... 95 3e-19
AL807772-3|CAI39687.1| 740|Homo sapiens ribosomal protein S6 ki... 95 3e-19
AL732366-2|CAI40548.1| 740|Homo sapiens ribosomal protein S6 ki... 95 3e-19
AF080000-1|AAD23915.1| 802|Homo sapiens RSK-like protein kinase... 95 3e-19
AF074393-1|AAC31171.1| 802|Homo sapiens nuclear mitogen- and st... 95 3e-19
AB208933-1|BAD92170.1| 806|Homo sapiens ribosomal protein S6 ki... 95 3e-19
AB102662-1|BAC81131.1| 726|Homo sapiens RPS6KA3 protein. 95 3e-19
BC109097-1|AAI09098.2| 795|Homo sapiens MLCK protein protein. 94 4e-19
AJ247087-1|CAC42766.1| 795|Homo sapiens myosin light chain kina... 94 4e-19
M55284-1|AAA60100.1| 682|Homo sapiens protein kinase C-L protein. 94 5e-19
BC034044-1|AAH34044.1| 527|Homo sapiens calcium/calmodulin-depe... 94 5e-19
AL834498-1|CAD39156.1| 716|Homo sapiens hypothetical protein pr... 94 5e-19
AC093748-1|AAY40983.1| 443|Homo sapiens unknown protein. 94 5e-19
AB209181-1|BAD92418.1| 796|Homo sapiens Hypothetical protein DK... 94 5e-19
D70899-1|BAA18934.1| 762|Homo sapiens cGMP-dependent protein ki... 93 7e-19
CR536581-1|CAG38818.1| 429|Homo sapiens SGKL protein. 93 7e-19
BC015326-1|AAH15326.1| 496|Homo sapiens serum/glucocorticoid re... 93 7e-19
AK223523-1|BAD97243.1| 496|Homo sapiens serum/glucocorticoid re... 93 7e-19
AF169035-1|AAF12758.1| 429|Homo sapiens protein kinase protein. 93 7e-19
L07598-1|AAC82496.1| 540|Homo sapiens ribosomal protein S6 kina... 93 9e-19
AL023754-2|CAI19990.1| 245|Homo sapiens calcium/calmodulin-depe... 93 1e-18
BC048980-1|AAH48980.1| 574|Homo sapiens protein kinase, AMP-act... 92 2e-18
AF226044-1|AAF86944.1| 765|Homo sapiens HSNFRK protein. 92 2e-18
AF085233-1|AAF27051.2| 496|Homo sapiens SGK-like protein SGKL p... 92 2e-18
X85545-1|CAA59733.1| 358|Homo sapiens protein kinase protein. 91 3e-18
BC041073-1|AAH41073.1| 358|Homo sapiens protein kinase, X-linke... 91 3e-18
BC035354-1|AAH35354.1| 268|Homo sapiens testis-specific serine ... 91 3e-18
AY048701-1|AAL02128.1| 268|Homo sapiens TSSK3 protein. 91 3e-18
AL109945-4|CAI22888.1| 268|Homo sapiens testis-specific serine ... 91 3e-18
AF296450-1|AAK97141.1| 268|Homo sapiens testis-specific serine/... 91 3e-18
Y15801-1|CAA75792.1| 277|Homo sapiens protein kinase protein. 91 4e-18
Y13927-1|CAA74244.1| 277|Homo sapiens protein kinase protein. 91 4e-18
M60725-1|AAA36411.1| 502|Homo sapiens p70 ribosomal S6 kinase a... 91 4e-18
M60724-1|AAA36410.1| 525|Homo sapiens p70 ribosomal S6 kinase a... 91 4e-18
L20321-1|AAA36658.1| 841|Homo sapiens protein serine/threonine ... 91 4e-18
BC074852-1|AAH74852.1| 277|Homo sapiens protein kinase, Y-linke... 91 4e-18
BC074851-1|AAH74851.1| 277|Homo sapiens protein kinase, Y-linke... 91 4e-18
BC063044-1|AAH63044.1| 781|Homo sapiens NEK4 protein protein. 91 4e-18
BC053365-1|AAH53365.1| 451|Homo sapiens RPS6KB1 protein protein. 91 4e-18
BC015515-1|AAH15515.1| 451|Homo sapiens Unknown (protein for IM... 91 4e-18
AB058714-1|BAB47440.1| 715|Homo sapiens KIAA1811 protein protein. 91 4e-18
U66064-1|AAB80848.1| 315|Homo sapiens calcium/calmodulin-depend... 91 5e-18
L07599-1|AAC82495.1| 580|Homo sapiens ribosomal protein S6 kina... 91 5e-18
BC132833-1|AAI32834.1| 388|Homo sapiens hypothetical protein LO... 91 5e-18
BC132831-1|AAI32832.1| 388|Homo sapiens hypothetical protein LO... 91 5e-18
BC063885-1|AAH63885.1| 708|Homo sapiens NIMA (never in mitosis ... 91 5e-18
AL807772-1|CAI39684.1| 227|Homo sapiens ribosomal protein S6 ki... 91 5e-18
AL713896-5|CAI13790.1| 529|Homo sapiens calcium/calmodulin-depe... 91 5e-18
AL713896-4|CAI13789.1| 495|Homo sapiens calcium/calmodulin-depe... 91 5e-18
AL713896-3|CAI13791.1| 527|Homo sapiens calcium/calmodulin-depe... 91 5e-18
AL713896-2|CAI13788.1| 516|Homo sapiens calcium/calmodulin-depe... 91 5e-18
AL596247-5|CAI13965.1| 529|Homo sapiens calcium/calmodulin-depe... 91 5e-18
AL596247-4|CAI13966.1| 495|Homo sapiens calcium/calmodulin-depe... 91 5e-18
AL596247-3|CAI13968.1| 527|Homo sapiens calcium/calmodulin-depe... 91 5e-18
AL596247-2|CAI13967.1| 516|Homo sapiens calcium/calmodulin-depe... 91 5e-18
AL139092-1|CAH73662.1| 388|Homo sapiens protein ( Human DNA seq... 91 5e-18
AL139082-5|CAI12892.2| 708|Homo sapiens NIMA (never in mitosis ... 91 5e-18
AL138876-2|CAI12221.2| 388|Homo sapiens protein ( Human DNA seq... 91 5e-18
AF090421-1|AAC69577.1| 809|Homo sapiens ribosome S6 protein kin... 91 5e-18
U56998-1|AAC50637.1| 607|Homo sapiens putative serine/threonine... 90 7e-18
BC034511-1|AAH34511.1| 501|Homo sapiens PAK4 protein protein. 90 7e-18
BC025282-1|AAH25282.1| 591|Homo sapiens p21(CDKN1A)-activated k... 90 7e-18
BC013899-1|AAH13899.1| 646|Homo sapiens polo-like kinase 3 (Dro... 90 7e-18
BC011368-1|AAH11368.1| 591|Homo sapiens p21(CDKN1A)-activated k... 90 7e-18
BC002921-1|AAH02921.1| 426|Homo sapiens p21(CDKN1A)-activated k... 90 7e-18
AY764184-1|AAU88146.1| 646|Homo sapiens polo-like kinase 3 (Dro... 90 7e-18
AL592166-11|CAI13006.1| 646|Homo sapiens polo-like kinase 3 (Dr... 90 7e-18
AJ271722-1|CAB71146.1| 714|Homo sapiens putative serine/threoni... 90 7e-18
AJ011855-1|CAA09820.1| 591|Homo sapiens PAK4 protein protein. 90 7e-18
AF005046-1|AAD01210.1| 591|Homo sapiens serine/threonine kinase... 90 7e-18
AB209875-1|BAD93112.1| 621|Homo sapiens polo-like kinase 3 vari... 90 7e-18
AB032968-1|BAA86456.1| 467|Homo sapiens KIAA1142 protein protein. 90 7e-18
L07597-1|AAC82497.1| 735|Homo sapiens ribosomal protein S6 kina... 90 9e-18
BC014966-1|AAH14966.1| 735|Homo sapiens ribosomal protein S6 ki... 90 9e-18
BC006106-1|AAH06106.3| 482|Homo sapiens ribosomal protein S6 ki... 90 9e-18
AL627313-6|CAI14649.1| 735|Homo sapiens ribosomal protein S6 ki... 90 9e-18
AJ293866-1|CAC10659.1| 646|Homo sapiens FNK serine/threonine pr... 90 9e-18
X65293-1|CAA46388.1| 737|Homo sapiens protein kinase C epsilon... 89 1e-17
BC109034-1|AAI09035.1| 737|Homo sapiens protein kinase C, epsil... 89 1e-17
BC109033-1|AAI09034.1| 737|Homo sapiens protein kinase C, epsil... 89 1e-17
AB019245-1|BAA37145.1| 481|Homo sapiens S6 kinase b protein. 89 1e-17
EF560744-1|ABQ59054.1| 841|Homo sapiens NEK4 protein protein. 89 2e-17
BC032784-1|AAH32784.1| 478|Homo sapiens calcium/calmodulin-depe... 89 2e-17
AY987011-1|AAX88806.1| 489|Homo sapiens calcium/calmodulin-depe... 89 2e-17
AJ252239-1|CAB65123.1| 243|Homo sapiens calcium/calmodulin depe... 89 2e-17
AF071569-1|AAD20442.1| 499|Homo sapiens multifunctional calcium... 89 2e-17
AB209288-1|BAD92525.1| 522|Homo sapiens calcium/calmodulin-depe... 89 2e-17
U23460-1|AAC99802.1| 664|Homo sapiens proline rich calmodulin-d... 89 2e-17
BC019070-1|AAH19070.1| 503|Homo sapiens calcium/calmodulin-depe... 89 2e-17
AK222703-1|BAD96423.1| 542|Homo sapiens calcium/calmodulin-depe... 89 2e-17
AJ252238-1|CAB65122.1| 518|Homo sapiens calcium/calmodulin depe... 89 2e-17
AJ252237-1|CAB65121.1| 479|Homo sapiens calcium/calmodulin depe... 89 2e-17
AJ252236-1|CAB65120.1| 503|Homo sapiens calcium/calmodulin depe... 89 2e-17
AF140350-1|AAD42070.1| 449|Homo sapiens calcium/calmodulin-depe... 89 2e-17
AF083419-1|AAD42038.1| 517|Homo sapiens calcium/calmodulin-depe... 89 2e-17
AF081924-1|AAD42037.1| 492|Homo sapiens calcium/calmodulin-depe... 89 2e-17
AF081572-1|AAD42036.1| 503|Homo sapiens calcium/calmodulin-depe... 89 2e-17
AF078803-1|AAD42035.1| 542|Homo sapiens calcium/calmodulin-depe... 89 2e-17
BC028713-1|AAH28713.1| 341|Homo sapiens PDLIM1 interacting kina... 78 2e-17
AL391650-6|CAI17135.1| 341|Homo sapiens PDLIM1 interacting kina... 78 2e-17
BC022558-1|AAH22558.1| 344|Homo sapiens CAMK2D protein protein. 88 3e-17
BC000094-1|AAH00094.3| 482|Homo sapiens ribosomal protein S6 ki... 88 3e-17
AF099739-1|AAD20990.1| 482|Homo sapiens S6 kinase-related kinas... 88 3e-17
AF076931-1|AAD46063.1| 482|Homo sapiens serine/threonine kinase... 88 3e-17
AB016869-1|BAA34402.1| 495|Homo sapiens p70 ribosomal S6 kinase... 88 3e-17
M34182-1|AAC41690.1| 360|Homo sapiens protein kinase A gamma-su... 88 3e-17
M34181-1|AAA60170.1| 351|Homo sapiens cAMP-dependent protein ki... 88 3e-17
D63485-1|BAA09772.2| 723|Homo sapiens KIAA0151 protein. 88 3e-17
DQ667175-1|ABG25920.1| 351|Homo sapiens protein kinase, cAMP-de... 88 3e-17
DQ667174-1|ABG25919.1| 398|Homo sapiens protein kinase, cAMP-de... 88 3e-17
BC040457-1|AAH40457.1| 478|Homo sapiens calcium/calmodulin-depe... 88 3e-17
BC039888-1|AAH39888.1| 351|Homo sapiens protein kinase, cAMP-de... 88 3e-17
BC016285-1|AAH16285.1| 257|Homo sapiens protein kinase, cAMP-de... 88 3e-17
AL627313-4|CAI14647.1| 578|Homo sapiens ribosomal protein S6 ki... 88 3e-17
AL450063-11|CAI16854.1| 264|Homo sapiens protein kinase, cAMP-d... 88 3e-17
AL450063-10|CAI16853.1| 209|Homo sapiens protein kinase, cAMP-d... 88 3e-17
AL450063-7|CAI16850.1| 245|Homo sapiens protein kinase, cAMP-de... 88 3e-17
AL450063-6|CAI16849.1| 214|Homo sapiens protein kinase, cAMP-de... 88 3e-17
AL450063-3|CAI16846.1| 398|Homo sapiens protein kinase, cAMP-de... 88 3e-17
AL450063-2|CAI16845.1| 351|Homo sapiens protein kinase, cAMP-de... 88 3e-17
AL450063-1|CAI16844.1| 257|Homo sapiens protein kinase, cAMP-de... 88 3e-17
AL359504-2|CAI14541.1| 351|Homo sapiens protein kinase, cAMP-de... 88 3e-17
AL359504-1|CAI14540.1| 257|Homo sapiens protein kinase, cAMP-de... 88 3e-17
AL162730-1|CAH71828.1| 351|Homo sapiens protein kinase, cAMP-de... 88 3e-17
AK223561-1|BAD97281.1| 765|Homo sapiens ribosomal protein S6 ki... 88 3e-17
AJ010119-1|CAA09009.1| 772|Homo sapiens Ribosomal protein kinas... 88 3e-17
AJ001597-1|CAA04863.1| 351|Homo sapiens cAMP-dependent protein ... 88 3e-17
AF145711-1|AAD30559.1| 489|Homo sapiens calcium/calmodulin-depe... 88 3e-17
AF145710-1|AAD30558.1| 478|Homo sapiens calcium/calmodulin-depe... 88 3e-17
AF091486-1|AAD55815.1| 478|Homo sapiens calmodulin-dependent pr... 88 3e-17
AF074715-1|AAC67395.1| 705|Homo sapiens mitogen- and stress-act... 88 3e-17
AB209189-1|BAD92426.1| 365|Homo sapiens cAMP-dependent protein ... 88 3e-17
AB023185-1|BAA76812.1| 527|Homo sapiens KIAA0968 protein protein. 88 3e-17
BC113705-1|AAI13706.1| 692|Homo sapiens NIMA (never in mitosis ... 87 5e-17
BC112240-1|AAI12241.1| 692|Homo sapiens NIMA-related kinase 8 p... 87 5e-17
AY267371-1|AAP04006.1| 692|Homo sapiens NIMA-family kinase NEK8... 87 5e-17
AY242354-1|AAO88243.1| 692|Homo sapiens NIMA-related kinase 12a... 87 5e-17
AB209475-1|BAD92712.1| 461|Homo sapiens protein kinase C, alpha... 87 5e-17
BC047696-1|AAH47696.1| 414|Homo sapiens serine/threonine kinase... 87 6e-17
BC023508-1|AAH23508.2| 414|Homo sapiens serine/threonine kinase... 87 6e-17
BC013879-1|AAH13879.1| 685|Homo sapiens polo-like kinase 2 (Dro... 87 6e-17
AY461663-1|AAS17971.1| 328|Homo sapiens testis-specific serine ... 87 6e-17
AK098163-1|BAC05247.1| 372|Homo sapiens protein ( Homo sapiens ... 87 6e-17
AK074728-1|BAC11166.1| 240|Homo sapiens protein ( Homo sapiens ... 87 6e-17
AF223574-1|AAF62897.1| 685|Homo sapiens serum-inducible kinase ... 87 6e-17
AF059617-1|AAC14573.1| 685|Homo sapiens serum-inducible kinase ... 87 6e-17
AB011420-1|BAA34126.1| 414|Homo sapiens DRAK1 protein. 87 6e-17
X52479-1|CAA36718.1| 672|Homo sapiens protein ( Human PKC alpha... 87 8e-17
DQ667176-1|ABG25921.1| 716|Homo sapiens inhibitor of kappa ligh... 87 8e-17
BC109274-1|AAI09275.1| 672|Homo sapiens protein kinase C, alpha... 87 8e-17
BC109273-1|AAI09274.1| 672|Homo sapiens protein kinase C, alpha... 87 8e-17
BC105924-1|AAI05925.1| 716|Homo sapiens IKK-related kinase epsi... 87 8e-17
BC105923-1|AAI05924.1| 716|Homo sapiens inhibitor of kappa ligh... 87 8e-17
BC063585-1|AAH63585.1| 1323|Homo sapiens PAS domain containing s... 87 8e-17
BC043495-1|AAH43495.1| 953|Homo sapiens PASK protein protein. 87 8e-17
AY633609-1|AAV33302.1| 672|Homo sapiens aging-associated gene 6... 87 8e-17
AL354681-1|CAI15250.1| 716|Homo sapiens inhibitor of kappa ligh... 87 8e-17
AJ006701-1|CAA07196.1| 603|Homo sapiens putative serine/threoni... 87 8e-17
AF415197-1|AAM33514.1| 566|Homo sapiens calcium/calmodulin-depe... 87 8e-17
AF387103-1|AAK69752.1| 1323|Homo sapiens PAS-kinase protein. 87 8e-17
AF241789-1|AAF45307.1| 716|Homo sapiens IKK epsilon protein. 87 8e-17
AB016590-1|BAA85155.1| 716|Homo sapiens inducible IkappaB kinas... 87 8e-17
Z98752-6|CAI42313.1| 198|Homo sapiens serum/glucocorticoid regu... 86 1e-16
AF159295-1|AAD48007.1| 752|Homo sapiens serine/threonine protei... 86 1e-16
U79240-1|AAB50198.1| 458|Homo sapiens serine/threonine protein ... 86 1e-16
BC070077-1|AAH70077.1| 968|Homo sapiens serine/threonine kinase... 86 1e-16
BC035058-1|AAH35058.1| 351|Homo sapiens protein kinase, cAMP-de... 86 1e-16
AB015718-1|BAA35073.1| 968|Homo sapiens protein kinase protein. 86 1e-16
X07109-1|CAA30130.1| 673|Homo sapiens protein ( Human mRNA for ... 85 2e-16
X06318-1|CAA29634.1| 671|Homo sapiens protein ( Human mRNA for ... 85 2e-16
U42390-1|AAC34245.1| 2861|Homo sapiens Trio protein. 85 2e-16
U24153-1|AAA65442.1| 525|Homo sapiens p21-activated protein kin... 85 2e-16
M13975-1|AAA60095.1| 673|Homo sapiens protein kinase C beta-II ... 85 2e-16
BC036472-1|AAH36472.1| 673|Homo sapiens protein kinase C, beta ... 85 2e-16
BC017268-1|AAH17268.1| 383|Homo sapiens TRIO protein protein. 85 2e-16
AK131423-1|BAD18570.1| 596|Homo sapiens protein ( Homo sapiens ... 85 2e-16
AF091395-1|AAC43042.1| 3038|Homo sapiens Trio isoform protein. 85 2e-16
AC002299-2|AAB97934.1| 496|Homo sapiens Protein kinase C beta (... 85 2e-16
AC002299-1|AAB97933.1| 494|Homo sapiens Protein kinase C beta (... 85 2e-16
D86959-1|BAA13195.2| 1164|Homo sapiens KIAA0204 protein protein. 85 2e-16
BC126182-1|AAI26183.1| 385|Homo sapiens protein serine kinase H... 85 2e-16
BC126180-1|AAI26181.1| 385|Homo sapiens protein serine kinase H... 85 2e-16
BC114491-1|AAI14492.1| 1189|Homo sapiens NEK1 protein protein. 85 2e-16
BC111565-1|AAI11566.1| 1204|Homo sapiens SLK protein protein. 85 2e-16
BC064804-1|AAH64804.1| 617|Homo sapiens SLK protein protein. 85 2e-16
BC047885-1|AAH47885.1| 426|Homo sapiens SLK protein protein. 85 2e-16
BC047762-1|AAH47762.1| 614|Homo sapiens SLK protein protein. 85 2e-16
BC015147-1|AAH15147.1| 403|Homo sapiens Unknown (protein for IM... 85 2e-16
AY681966-1|AAV87216.1| 2069|Homo sapiens citron protein. 85 2e-16
AY257469-1|AAP13528.1| 2027|Homo sapiens rho/rac-interacting cit... 85 2e-16
AY037806-1|AAK59985.1| 385|Homo sapiens serine/threonine kinase... 85 2e-16
AL360170-2|CAH70404.1| 1235|Homo sapiens Ste20-related serine\/t... 85 2e-16
AL360170-1|CAH70403.1| 1204|Homo sapiens Ste20-related serine\/t... 85 2e-16
AL138761-2|CAI12395.1| 1235|Homo sapiens Ste20-related serine\/t... 85 2e-16
AL138761-1|CAI12396.1| 1204|Homo sapiens Ste20-related serine\/t... 85 2e-16
AF273048-1|AAG34908.1| 1235|Homo sapiens CTCL tumor antigen se20... 85 2e-16
AF112472-1|AAD03744.1| 542|Homo sapiens calcium/calmodulin-depe... 85 2e-16
AF112471-1|AAD03743.1| 517|Homo sapiens calcium/calmodulin-depe... 85 2e-16
AB067488-1|BAB67794.1| 1265|Homo sapiens KIAA1901 protein protein. 85 2e-16
AB002804-1|BAA19655.1| 1204|Homo sapiens hSLK protein. 85 2e-16
D79997-1|BAA11492.2| 656|Homo sapiens KIAA0175 protein. 85 3e-16
BC108694-1|AAI08695.1| 420|Homo sapiens IKBKB protein protein. 85 3e-16
BC038807-1|AAH38807.1| 349|Homo sapiens ALS2CR7 protein protein. 85 3e-16
BC035596-1|AAH35596.1| 681|Homo sapiens PAK6 protein protein. 85 3e-16
BC014039-1|AAH14039.1| 651|Homo sapiens maternal embryonic leuc... 85 3e-16
BC006231-1|AAH06231.1| 256|Homo sapiens IKBKB protein protein. 85 3e-16
AY663108-1|AAT65965.1| 756|Homo sapiens inhibitor of kappa ligh... 85 3e-16
AL442063-1|CAI16995.2| 651|Homo sapiens maternal embryonic leuc... 85 3e-16
AL354932-1|CAI11034.2| 651|Homo sapiens maternal embryonic leuc... 85 3e-16
AK222811-1|BAD96531.1| 651|Homo sapiens maternal embryonic leuc... 85 3e-16
AJ236915-1|CAC18720.1| 681|Homo sapiens pak5 protein protein. 85 3e-16
AF276893-1|AAF82800.1| 681|Homo sapiens p21-activated protein k... 85 3e-16
AF080158-1|AAD08997.1| 756|Homo sapiens IkB kinase-b protein. 85 3e-16
AF031416-1|AAC64675.1| 756|Homo sapiens IkB kinase beta subunit... 85 3e-16
AF029684-1|AAC51860.1| 756|Homo sapiens IkB kinase-beta protein. 85 3e-16
AC007242-1|AAX93182.1| 301|Homo sapiens unknown protein. 85 3e-16
AB053308-1|BAB69017.1| 384|Homo sapiens ALS2CR7 protein. 85 3e-16
Z48615-1|CAA88531.1| 953|Homo sapiens serine/threonine kinase w... 84 4e-16
X90846-1|CAA62351.1| 954|Homo sapiens mixed lineage kinase 2 pr... 84 4e-16
X66363-1|CAA47006.1| 496|Homo sapiens serine/threonine protein ... 84 4e-16
U51120-1|AAC50590.1| 545|Homo sapiens PAK1 protein. 84 4e-16
M95936-1|AAA58364.1| 481|Homo sapiens protein serine/threonine ... 84 4e-16
M77198-1|AAA36585.1| 520|Homo sapiens rac protein kinase-beta p... 84 4e-16
BT006827-1|AAP35473.1| 496|Homo sapiens PCTAIRE protein kinase ... 84 4e-16
BC120994-1|AAI20995.1| 481|Homo sapiens v-akt murine thymoma vi... 84 4e-16
BC032709-1|AAH32709.1| 344|Homo sapiens AKT2 protein protein. 84 4e-16
BC017575-1|AAH17575.1| 476|Homo sapiens CHK1 checkpoint homolog... 84 4e-16
BC015607-1|AAH15607.1| 496|Homo sapiens PCTAIRE protein kinase ... 84 4e-16
BC009852-1|AAH09852.2| 395|Homo sapiens PCTK1 protein protein. 84 4e-16
BC006190-1|AAH06190.1| 448|Homo sapiens PCTK1 protein protein. 84 4e-16
BC004202-1|AAH04202.1| 476|Homo sapiens CHEK1 protein protein. 84 4e-16
BC001048-1|AAH01048.1| 496|Homo sapiens PCTAIRE protein kinase ... 84 4e-16
AL670729-4|CAH71670.2| 2582|Homo sapiens obscurin, cytoskeletal ... 84 4e-16
AL353593-4|CAM27610.1| 2582|Homo sapiens obscurin, cytoskeletal ... 84 4e-16
AL096791-1|CAD20055.1| 496|Homo sapiens PCTAIRE protein kinase ... 84 4e-16
AF527555-1|AAM78553.1| 476|Homo sapiens CHK1 checkpoint homolog... 84 4e-16
AF032874-1|AAB88852.1| 476|Homo sapiens protein kinase protein. 84 4e-16
AF016582-1|AAC51736.1| 476|Homo sapiens Chk1 protein. 84 4e-16
AB046859-1|BAB13465.2| 2584|Homo sapiens KIAA1639 protein protein. 84 4e-16
AB032387-1|BAA84577.1| 476|Homo sapiens checkpoint kinase protein. 84 4e-16
X66362-1|CAA47005.1| 380|Homo sapiens serine/threonine protein ... 84 6e-16
BC075064-1|AAH75064.2| 275|Homo sapiens AURKC protein protein. 84 6e-16
BC041799-1|AAH41799.1| 592|Homo sapiens CDKL3 protein protein. 84 6e-16
AY714054-1|AAU04399.1| 306|Homo sapiens aurora-C protein. 84 6e-16
AY661554-1|AAT64422.1| 290|Homo sapiens aurora/Ipl1-related kin... 84 6e-16
AY209000-1|AAP43922.1| 482|Homo sapiens citron Rho-interacting ... 84 6e-16
AL450063-9|CAI16852.1| 197|Homo sapiens protein kinase, cAMP-de... 84 6e-16
AF130372-1|AAF36509.1| 455|Homo sapiens serine-threonine protei... 84 6e-16
AB020641-1|BAA74857.2| 453|Homo sapiens KIAA0834 protein protein. 84 6e-16
AB017332-1|BAA76292.1| 309|Homo sapiens Aurora/Ipl1-related kin... 84 6e-16
AF054621-1|AAC25955.1| 309|Homo sapiens serine/threonine kinase... 83 7e-16
AB011422-1|BAA76314.1| 1289|Homo sapiens Trad protein. 83 7e-16
Y15056-1|CAA75341.1| 556|Homo sapiens PkB kinase protein. 83 1e-15
U24152-1|AAA65441.1| 545|Homo sapiens p21-activated protein kin... 83 1e-15
CR536517-1|CAG38755.1| 556|Homo sapiens PDPK1 protein. 83 1e-15
BT007185-1|AAP35849.1| 898|Homo sapiens STE20-like kinase protein. 83 1e-15
BC127622-1|AAI27623.1| 596|Homo sapiens myosin light chain kina... 83 1e-15
BC109299-1|AAI09300.1| 545|Homo sapiens p21/Cdc42/Rac1-activate... 83 1e-15
BC092413-1|AAH92413.1| 596|Homo sapiens myosin light chain kina... 83 1e-15
BC069627-1|AAH69627.1| 596|Homo sapiens skeletal myosin light c... 83 1e-15
BC024179-1|AAH24179.1| 719|Homo sapiens p21(CDKN1A)-activated k... 83 1e-15
BC012103-1|AAH12103.1| 556|Homo sapiens 3-phosphoinositide depe... 83 1e-15
BC002756-1|AAH02756.1| 898|Homo sapiens TAO kinase 3 protein. 83 1e-15
AY353238-1|AAR13066.1| 504|Homo sapiens PCTAIRE protein kinase ... 83 1e-15
AY353237-1|AAR13065.1| 474|Homo sapiens PCTAIRE protein kinase ... 83 1e-15
AM231061-1|CAJ76912.1| 1960|Homo sapiens obscurin isoform B prot... 83 1e-15
AL357131-4|CAH72012.1| 472|Homo sapiens PCTAIRE protein kinase ... 83 1e-15
AL353612-1|CAI23529.1| 719|Homo sapiens p21(CDKN1A)-activated k... 83 1e-15
AL160175-10|CAC10006.1| 596|Homo sapiens myosin light chain kin... 83 1e-15
AL135935-1|CAH71126.1| 719|Homo sapiens p21(CDKN1A)-activated k... 83 1e-15
AL031652-1|CAI42211.1| 719|Homo sapiens p21(CDKN1A)-activated k... 83 1e-15
AJ785968-1|CAH05056.1| 396|Homo sapiens PDPK2 protein protein. 83 1e-15
AJ272502-1|CAC81354.1| 596|Homo sapiens skeletal muscle-specifi... 83 1e-15
AF325549-1|AAK15494.1| 596|Homo sapiens skeletal myosin light c... 83 1e-15
AF179867-1|AAF14559.1| 898|Homo sapiens STE20-like kinase protein. 83 1e-15
>AF045458-1|AAC32326.1| 1050|Homo sapiens serine/threonine kinase
ULK1 protein.
Length = 1050
Score = 232 bits (568), Expect = 8e-61
Identities = 113/190 (59%), Positives = 145/190 (76%)
Frame = +3
Query: 156 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILREL 335
VG +EF+++D+IGHGAFA+V+KGR R+ VAVK + KK + K+ +L KEIKIL+EL
Sbjct: 11 VGKFEFSRKDLIGHGAFAVVFKGRHREKHDLEVAVKCINKKNLAKSQTLLGKEIKILKEL 70
Query: 336 TALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMS 515
+H+N+VA++D + VY+VMEYCNGGDLADYL R LSE TI+LFL Q+A AM
Sbjct: 71 ---KHENIVALYDFQEMANSVYLVMEYCNGGDLADYLHAMRTLSEDTIRLFLQQIAGAMR 127
Query: 516 AIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSP 695
+H+KGI+HRDLKPQNILL++ R +P+ I +KIADFGFAR+L+ MA TLCGSP
Sbjct: 128 LLHSKGIIHRDLKPQNILLSNP--AGRRANPNSIRVKIADFGFARYLQSNMMAATLCGSP 185
Query: 696 MYMAPEVIMS 725
MYMAPEVIMS
Sbjct: 186 MYMAPEVIMS 195
>AB018265-1|BAA34442.2| 1066|Homo sapiens KIAA0722 protein protein.
Length = 1066
Score = 232 bits (568), Expect = 8e-61
Identities = 113/190 (59%), Positives = 145/190 (76%)
Frame = +3
Query: 156 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILREL 335
VG +EF+++D+IGHGAFA+V+KGR R+ VAVK + KK + K+ +L KEIKIL+EL
Sbjct: 27 VGKFEFSRKDLIGHGAFAVVFKGRHREKHDLEVAVKCINKKNLAKSQTLLGKEIKILKEL 86
Query: 336 TALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMS 515
+H+N+VA++D + VY+VMEYCNGGDLADYL R LSE TI+LFL Q+A AM
Sbjct: 87 ---KHENIVALYDFQEMANSVYLVMEYCNGGDLADYLHAMRTLSEDTIRLFLQQIAGAMR 143
Query: 516 AIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSP 695
+H+KGI+HRDLKPQNILL++ R +P+ I +KIADFGFAR+L+ MA TLCGSP
Sbjct: 144 LLHSKGIIHRDLKPQNILLSNP--AGRRANPNSIRVKIADFGFARYLQSNMMAATLCGSP 201
Query: 696 MYMAPEVIMS 725
MYMAPEVIMS
Sbjct: 202 MYMAPEVIMS 211
>BC034988-1|AAH34988.1| 1036|Homo sapiens ULK2 protein protein.
Length = 1036
Score = 232 bits (567), Expect = 1e-60
Identities = 114/195 (58%), Positives = 148/195 (75%)
Frame = +3
Query: 141 MEVIQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIK 320
MEV VGD+E++K+D++GHGAFA+V++GR R+ VA+K + KK + K+ +L KEIK
Sbjct: 1 MEV--VGDFEYSKRDLVGHGAFAVVFRGRHRQKTDWEVAIKSINKKNLSKSQILLGKEIK 58
Query: 321 ILRELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQL 500
IL+EL QH+N+VA++D + P V++VMEYCNGGDLADYLQ LSE TI++FL Q+
Sbjct: 59 ILKEL---QHENIVALYDVQELPNSVFLVMEYCNGGDLADYLQAKGTLSEDTIRVFLHQI 115
Query: 501 AEAMSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVT 680
A AM +H+KGI+HRDLKPQNILL+++ R S I +KIADFGFAR+L MA T
Sbjct: 116 AAAMRILHSKGIIHRDLKPQNILLSYA--NRRKSSVSGIRIKIADFGFARYLHSNMMAAT 173
Query: 681 LCGSPMYMAPEVIMS 725
LCGSPMYMAPEVIMS
Sbjct: 174 LCGSPMYMAPEVIMS 188
>AB014523-1|BAA31598.2| 1100|Homo sapiens KIAA0623 protein protein.
Length = 1100
Score = 232 bits (567), Expect = 1e-60
Identities = 114/195 (58%), Positives = 148/195 (75%)
Frame = +3
Query: 141 MEVIQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIK 320
MEV VGD+E++K+D++GHGAFA+V++GR R+ VA+K + KK + K+ +L KEIK
Sbjct: 65 MEV--VGDFEYSKRDLVGHGAFAVVFRGRHRQKTDWEVAIKSINKKNLSKSQILLGKEIK 122
Query: 321 ILRELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQL 500
IL+EL QH+N+VA++D + P V++VMEYCNGGDLADYLQ LSE TI++FL Q+
Sbjct: 123 ILKEL---QHENIVALYDVQELPNSVFLVMEYCNGGDLADYLQAKGTLSEDTIRVFLHQI 179
Query: 501 AEAMSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVT 680
A AM +H+KGI+HRDLKPQNILL+++ R S I +KIADFGFAR+L MA T
Sbjct: 180 AAAMRILHSKGIIHRDLKPQNILLSYA--NRRKSSVSGIRIKIADFGFARYLHSNMMAAT 237
Query: 681 LCGSPMYMAPEVIMS 725
LCGSPMYMAPEVIMS
Sbjct: 238 LCGSPMYMAPEVIMS 252
>BC056423-1|AAH56423.1| 214|Homo sapiens ULK3 protein protein.
Length = 214
Score = 136 bits (328), Expect = 1e-31
Identities = 74/184 (40%), Positives = 112/184 (60%), Gaps = 1/184 (0%)
Frame = +3
Query: 171 FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKILRELTALQ 347
F + +G G +A VYK +K+ + VA+K V KK + KAS E L+ EI+IL+ ++
Sbjct: 14 FILTERLGSGTYATVYKAYAKKDTREVVAIKCVAKKSLNKASVENLLTEIEILK---GIR 70
Query: 348 HKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHA 527
H ++V + D +Y++ME+C GGDL+ ++ T R+L E ++F+ QLA A+ +H
Sbjct: 71 HPHIVQLKDFQWDSDNIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQQLASALQFLHE 130
Query: 528 KGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYMA 707
+ I H DLKPQNILL+ PH LK+ADFGFA+ + + L GSP+YMA
Sbjct: 131 RNISHLDLKPQNILLSSL----EKPH-----LKLADFGFAQHMSPWDEKHVLRGSPLYMA 181
Query: 708 PEVI 719
PE++
Sbjct: 182 PEMV 185
>BC036117-1|AAH36117.1| 214|Homo sapiens ULK3 protein protein.
Length = 214
Score = 136 bits (328), Expect = 1e-31
Identities = 74/184 (40%), Positives = 112/184 (60%), Gaps = 1/184 (0%)
Frame = +3
Query: 171 FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKILRELTALQ 347
F + +G G +A VYK +K+ + VA+K V KK + KAS E L+ EI+IL+ ++
Sbjct: 14 FILTERLGSGTYATVYKAYAKKDTREVVAIKCVAKKSLNKASVENLLTEIEILK---GIR 70
Query: 348 HKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHA 527
H ++V + D +Y++ME+C GGDL+ ++ T R+L E ++F+ QLA A+ +H
Sbjct: 71 HPHIVQLKDFQWDSDNIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQQLASALQFLHE 130
Query: 528 KGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYMA 707
+ I H DLKPQNILL+ PH LK+ADFGFA+ + + L GSP+YMA
Sbjct: 131 RNISHLDLKPQNILLSSL----EKPH-----LKLADFGFAQHMSPWDEKHVLRGSPLYMA 181
Query: 708 PEVI 719
PE++
Sbjct: 182 PEMV 185
>BC117183-1|AAI17184.1| 926|Homo sapiens SNF1-like kinase 2
protein.
Length = 926
Score = 113 bits (272), Expect = 6e-25
Identities = 63/190 (33%), Positives = 109/190 (57%), Gaps = 1/190 (0%)
Frame = +3
Query: 150 IQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKIL 326
++VG Y+ + +G G FA+V GR R ++ VA+K++ K + + E + +E++I+
Sbjct: 15 VRVGFYDI--EGTLGKGNFAVVKLGRHRITKTE-VAIKIIDKSQLDAVNLEKIYREVQIM 71
Query: 327 RELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAE 506
+ L H +++ ++ M++ + +Y+V EY G++ DYL + L+E+ + Q+
Sbjct: 72 K---MLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILS 128
Query: 507 AMSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLC 686
A+ H + IVHRDLK +N+LL +++ +KIADFGF F + G + T C
Sbjct: 129 AVDYCHGRKIVHRDLKAENLLL-----------DNNMNIKIADFGFGNFFKSGELLATWC 177
Query: 687 GSPMYMAPEV 716
GSP Y APEV
Sbjct: 178 GSPPYAAPEV 187
>BC113459-1|AAI13460.1| 926|Homo sapiens SNF1-like kinase 2
protein.
Length = 926
Score = 113 bits (272), Expect = 6e-25
Identities = 63/190 (33%), Positives = 109/190 (57%), Gaps = 1/190 (0%)
Frame = +3
Query: 150 IQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKIL 326
++VG Y+ + +G G FA+V GR R ++ VA+K++ K + + E + +E++I+
Sbjct: 15 VRVGFYDI--EGTLGKGNFAVVKLGRHRITKTE-VAIKIIDKSQLDAVNLEKIYREVQIM 71
Query: 327 RELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAE 506
+ L H +++ ++ M++ + +Y+V EY G++ DYL + L+E+ + Q+
Sbjct: 72 K---MLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILS 128
Query: 507 AMSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLC 686
A+ H + IVHRDLK +N+LL +++ +KIADFGF F + G + T C
Sbjct: 129 AVDYCHGRKIVHRDLKAENLLL-----------DNNMNIKIADFGFGNFFKSGELLATWC 177
Query: 687 GSPMYMAPEV 716
GSP Y APEV
Sbjct: 178 GSPPYAAPEV 187
>AB084424-1|BAB91442.1| 346|Homo sapiens KIAA0781 protein protein.
Length = 346
Score = 113 bits (272), Expect = 6e-25
Identities = 63/190 (33%), Positives = 109/190 (57%), Gaps = 1/190 (0%)
Frame = +3
Query: 150 IQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKIL 326
++VG Y+ + +G G FA+V GR R ++ VA+K++ K + + E + +E++I+
Sbjct: 13 VRVGFYDI--EGTLGKGNFAVVKLGRHRITKTE-VAIKIIDKSQLDAVNLEKIYREVQIM 69
Query: 327 RELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAE 506
+ L H +++ ++ M++ + +Y+V EY G++ DYL + L+E+ + Q+
Sbjct: 70 K---MLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILS 126
Query: 507 AMSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLC 686
A+ H + IVHRDLK +N+LL +++ +KIADFGF F + G + T C
Sbjct: 127 AVDYCHGRKIVHRDLKAENLLL-----------DNNMNIKIADFGFGNFFKSGELLATWC 175
Query: 687 GSPMYMAPEV 716
GSP Y APEV
Sbjct: 176 GSPPYAAPEV 185
>AB018324-1|BAA34501.3| 950|Homo sapiens KIAA0781 protein protein.
Length = 950
Score = 113 bits (272), Expect = 6e-25
Identities = 63/190 (33%), Positives = 109/190 (57%), Gaps = 1/190 (0%)
Frame = +3
Query: 150 IQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKIL 326
++VG Y+ + +G G FA+V GR R ++ VA+K++ K + + E + +E++I+
Sbjct: 39 VRVGFYDI--EGTLGKGNFAVVKLGRHRITKTE-VAIKIIDKSQLDAVNLEKIYREVQIM 95
Query: 327 RELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAE 506
+ L H +++ ++ M++ + +Y+V EY G++ DYL + L+E+ + Q+
Sbjct: 96 K---MLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILS 152
Query: 507 AMSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLC 686
A+ H + IVHRDLK +N+LL +++ +KIADFGF F + G + T C
Sbjct: 153 AVDYCHGRKIVHRDLKAENLLL-----------DNNMNIKIADFGFGNFFKSGELLATWC 201
Query: 687 GSPMYMAPEV 716
GSP Y APEV
Sbjct: 202 GSPPYAAPEV 211
>X97630-1|CAA66229.1| 745|Homo sapiens serine/threonine protein
kinase protein.
Length = 745
Score = 110 bits (264), Expect = 6e-24
Identities = 67/188 (35%), Positives = 103/188 (54%), Gaps = 1/188 (0%)
Frame = +3
Query: 156 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKILRE 332
+G+Y K IG G FA V R + VAVK++ K + +S + L +E++I++
Sbjct: 17 IGNYRLLKT--IGKGNFAKVKLARHILT-GKEVAVKIIDKTQLNSSSLQKLFREVRIMK- 72
Query: 333 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 512
L H N+V + + +++ +Y+VMEY +GG++ DYL + + E + Q+ A+
Sbjct: 73 --VLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAV 130
Query: 513 SAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGS 692
H K IVHRDLK +N+LL +D+ +KIADFGF+ GN T CGS
Sbjct: 131 QYCHQKFIVHRDLKAENLLL-----------DADMNIKIADFGFSNEFTFGNKLDTFCGS 179
Query: 693 PMYMAPEV 716
P Y APE+
Sbjct: 180 PPYAAPEL 187
>BT007342-1|AAP36006.1| 755|Homo sapiens MAP/microtubule
affinity-regulating kinase 2 protein.
Length = 755
Score = 110 bits (264), Expect = 6e-24
Identities = 67/188 (35%), Positives = 103/188 (54%), Gaps = 1/188 (0%)
Frame = +3
Query: 156 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKILRE 332
+G+Y K IG G FA V R + VAVK++ K + +S + L +E++I++
Sbjct: 17 IGNYRLLKT--IGKGNFAKVKLARHILT-GKEVAVKIIDKTQLNSSSLQKLFREVRIMK- 72
Query: 333 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 512
L H N+V + + +++ +Y+VMEY +GG++ DYL + + E + Q+ A+
Sbjct: 73 --VLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAV 130
Query: 513 SAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGS 692
H K IVHRDLK +N+LL +D+ +KIADFGF+ GN T CGS
Sbjct: 131 QYCHQKFIVHRDLKAENLLL-----------DADMNIKIADFGFSNEFTFGNKLDTFCGS 179
Query: 693 PMYMAPEV 716
P Y APE+
Sbjct: 180 PPYAAPEL 187
>BC084540-1|AAH84540.1| 724|Homo sapiens MAP/microtubule
affinity-regulating kinase 2 protein.
Length = 724
Score = 110 bits (264), Expect = 6e-24
Identities = 67/188 (35%), Positives = 103/188 (54%), Gaps = 1/188 (0%)
Frame = +3
Query: 156 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKILRE 332
+G+Y K IG G FA V R + VAVK++ K + +S + L +E++I++
Sbjct: 50 IGNYRLLKT--IGKGNFAKVKLARHILT-GKEVAVKIIDKTQLNSSSLQKLFREVRIMK- 105
Query: 333 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 512
L H N+V + + +++ +Y+VMEY +GG++ DYL + + E + Q+ A+
Sbjct: 106 --VLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAV 163
Query: 513 SAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGS 692
H K IVHRDLK +N+LL +D+ +KIADFGF+ GN T CGS
Sbjct: 164 QYCHQKFIVHRDLKAENLLL-----------DADMNIKIADFGFSNEFTFGNKLDTFCGS 212
Query: 693 PMYMAPEV 716
P Y APE+
Sbjct: 213 PPYAAPEL 220
>BC026158-1|AAH26158.1| 1315|Homo sapiens serine/threonine kinase
36, fused homolog (Drosophila) protein.
Length = 1315
Score = 110 bits (264), Expect = 6e-24
Identities = 70/181 (38%), Positives = 104/181 (57%), Gaps = 2/181 (1%)
Frame = +3
Query: 183 DIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKG-IQKASEILVKEIKILRELTALQHKNL 359
++IG G+F VYKGR RK +Q VA+K + K G +K L +EI+I+R L+H N+
Sbjct: 8 EMIGEGSFGRVYKGR-RKYSAQVVALKFIPKLGRSEKELRNLQREIEIMR---GLRHPNI 63
Query: 360 VAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIV 539
V M D ++ V VV +Y G +L L+ + L E +Q AQL A+ +H+ I+
Sbjct: 64 VHMLDSFETDKEVVVVTDYAEG-ELFQILEDDGKLPEDQVQAIAAQLVSALYYLHSHRIL 122
Query: 540 HRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVT-LCGSPMYMAPEV 716
HRD+KPQNILL +K+ DFGFAR + M +T + G+P+YM+PE+
Sbjct: 123 HRDMKPQNILLA-----------KGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPEL 171
Query: 717 I 719
+
Sbjct: 172 V 172
>BC008771-1|AAH08771.2| 778|Homo sapiens MARK2 protein protein.
Length = 778
Score = 110 bits (264), Expect = 6e-24
Identities = 67/188 (35%), Positives = 103/188 (54%), Gaps = 1/188 (0%)
Frame = +3
Query: 156 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKILRE 332
+G+Y K IG G FA V R + VAVK++ K + +S + L +E++I++
Sbjct: 40 IGNYRLLKT--IGKGNFAKVKLARHILT-GKEVAVKIIDKTQLNSSSLQKLFREVRIMK- 95
Query: 333 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 512
L H N+V + + +++ +Y+VMEY +GG++ DYL + + E + Q+ A+
Sbjct: 96 --VLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAV 153
Query: 513 SAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGS 692
H K IVHRDLK +N+LL +D+ +KIADFGF+ GN T CGS
Sbjct: 154 QYCHQKFIVHRDLKAENLLL-----------DADMNIKIADFGFSNEFTFGNKLDTFCGS 202
Query: 693 PMYMAPEV 716
P Y APE+
Sbjct: 203 PPYAAPEL 210
>AF387638-1|AAK82368.1| 691|Homo sapiens Ser/Thr protein kinase
PAR-1Balpha protein.
Length = 691
Score = 110 bits (264), Expect = 6e-24
Identities = 67/188 (35%), Positives = 103/188 (54%), Gaps = 1/188 (0%)
Frame = +3
Query: 156 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKILRE 332
+G+Y K IG G FA V R + VAVK++ K + +S + L +E++I++
Sbjct: 17 IGNYRLLKT--IGKGNFAKVKLARHILT-GKEVAVKIIDKTQLNSSSLQKLFREVRIMK- 72
Query: 333 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 512
L H N+V + + +++ +Y+VMEY +GG++ DYL + + E + Q+ A+
Sbjct: 73 --VLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAV 130
Query: 513 SAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGS 692
H K IVHRDLK +N+LL +D+ +KIADFGF+ GN T CGS
Sbjct: 131 QYCHQKFIVHRDLKAENLLL-----------DADMNIKIADFGFSNEFTFGNKLDTFCGS 179
Query: 693 PMYMAPEV 716
P Y APE+
Sbjct: 180 PPYAAPEL 187
>AF200815-1|AAF97028.1| 1315|Homo sapiens FUSED serine/threonine
kinase protein.
Length = 1315
Score = 110 bits (264), Expect = 6e-24
Identities = 70/181 (38%), Positives = 104/181 (57%), Gaps = 2/181 (1%)
Frame = +3
Query: 183 DIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKG-IQKASEILVKEIKILRELTALQHKNL 359
++IG G+F VYKGR RK +Q VA+K + K G +K L +EI+I+R L+H N+
Sbjct: 8 EMIGEGSFGRVYKGR-RKYSAQVVALKFIPKLGRSEKELRNLQREIEIMR---GLRHPNI 63
Query: 360 VAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIV 539
V M D ++ V VV +Y G +L L+ + L E +Q AQL A+ +H+ I+
Sbjct: 64 VHMLDSFETDKEVVVVTDYAEG-ELFQILEDDGKLPEDQVQAIAAQLVSALYYLHSHRIL 122
Query: 540 HRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVT-LCGSPMYMAPEV 716
HRD+KPQNILL +K+ DFGFAR + M +T + G+P+YM+PE+
Sbjct: 123 HRDMKPQNILLA-----------KGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPEL 171
Query: 717 I 719
+
Sbjct: 172 V 172
>AB188493-1|BAD37141.1| 719|Homo sapiens serine/threonine kinase
protein.
Length = 719
Score = 110 bits (264), Expect = 6e-24
Identities = 67/188 (35%), Positives = 103/188 (54%), Gaps = 1/188 (0%)
Frame = +3
Query: 156 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKILRE 332
+G+Y K IG G FA V R + VAVK++ K + +S + L +E++I++
Sbjct: 50 IGNYRLLKT--IGKGNFAKVKLARHILT-GKEVAVKIIDKTQLNSSSLQKLFREVRIMK- 105
Query: 333 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 512
L H N+V + + +++ +Y+VMEY +GG++ DYL + + E + Q+ A+
Sbjct: 106 --VLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAV 163
Query: 513 SAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGS 692
H K IVHRDLK +N+LL +D+ +KIADFGF+ GN T CGS
Sbjct: 164 QYCHQKFIVHRDLKAENLLL-----------DADMNIKIADFGFSNEFTFGNKLDTFCGS 212
Query: 693 PMYMAPEV 716
P Y APE+
Sbjct: 213 PPYAAPEL 220
>AB051552-1|BAB21856.1| 608|Homo sapiens KIAA1765 protein protein.
Length = 608
Score = 110 bits (264), Expect = 6e-24
Identities = 60/178 (33%), Positives = 103/178 (57%)
Frame = +3
Query: 186 IIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQHKNLVA 365
+IG G FA+V + R R+ Q+ A+K++ K ++ +++ EI I++ L+ H N+V
Sbjct: 321 VIGDGNFAVVKECRHRET-RQAYAMKIIDKSRLKGKEDMVDSEILIIQSLS---HPNIVK 376
Query: 366 MHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIVHR 545
+H+ ++ +Y+++EY GGDL D + + E L + L +A+ +H K IVHR
Sbjct: 377 LHEVYETDMEIYLILEYVQGGDLFDAIIESVKFPEPDAALMIMDLCKALVHMHDKSIVHR 436
Query: 546 DLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYMAPEVI 719
DLKP+N+L+ + TLK+ADFG A+ + T+CG+P Y+APE++
Sbjct: 437 DLKPENLLVQRN-------EDKSTTLKLADFGLAKHVV--RPIFTVCGTPTYVAPEIL 485
>AB033104-1|BAA86592.1| 1311|Homo sapiens KIAA1278 protein protein.
Length = 1311
Score = 110 bits (264), Expect = 6e-24
Identities = 70/181 (38%), Positives = 104/181 (57%), Gaps = 2/181 (1%)
Frame = +3
Query: 183 DIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKG-IQKASEILVKEIKILRELTALQHKNL 359
++IG G+F VYKGR RK +Q VA+K + K G +K L +EI+I+R L+H N+
Sbjct: 25 EMIGEGSFGRVYKGR-RKYSAQVVALKFIPKLGRSEKELRNLQREIEIMR---GLRHPNI 80
Query: 360 VAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIV 539
V M D ++ V VV +Y G +L L+ + L E +Q AQL A+ +H+ I+
Sbjct: 81 VHMLDSFETDKEVVVVTDYAEG-ELFQILEDDGKLPEDQVQAIAAQLVSALYYLHSHRIL 139
Query: 540 HRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVT-LCGSPMYMAPEV 716
HRD+KPQNILL +K+ DFGFAR + M +T + G+P+YM+PE+
Sbjct: 140 HRDMKPQNILLA-----------KGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPEL 188
Query: 717 I 719
+
Sbjct: 189 V 189
>BC114478-1|AAI14479.1| 795|Homo sapiens MARK1 protein protein.
Length = 795
Score = 109 bits (262), Expect = 1e-23
Identities = 67/188 (35%), Positives = 102/188 (54%), Gaps = 1/188 (0%)
Frame = +3
Query: 156 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKILRE 332
+G+Y K IG G FA V K + + VAVK++ K + S + L +E++I++
Sbjct: 57 IGNYRLQKT--IGKGNFAKV-KLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMK- 112
Query: 333 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 512
L H N+V + + +++ +Y+VMEY +GG++ DYL + + E + Q+ A+
Sbjct: 113 --ILNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAV 170
Query: 513 SAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGS 692
H K IVHRDLK +N+LL D+ +KIADFGF+ GN T CGS
Sbjct: 171 QYCHQKYIVHRDLKAENLLL-----------DGDMNIKIADFGFSNEFTVGNKLDTFCGS 219
Query: 693 PMYMAPEV 716
P Y APE+
Sbjct: 220 PPYAAPEL 227
>BC113869-1|AAI13870.1| 795|Homo sapiens MARK1 protein protein.
Length = 795
Score = 109 bits (262), Expect = 1e-23
Identities = 67/188 (35%), Positives = 102/188 (54%), Gaps = 1/188 (0%)
Frame = +3
Query: 156 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKILRE 332
+G+Y K IG G FA V K + + VAVK++ K + S + L +E++I++
Sbjct: 57 IGNYRLQKT--IGKGNFAKV-KLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMK- 112
Query: 333 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 512
L H N+V + + +++ +Y+VMEY +GG++ DYL + + E + Q+ A+
Sbjct: 113 --ILNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAV 170
Query: 513 SAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGS 692
H K IVHRDLK +N+LL D+ +KIADFGF+ GN T CGS
Sbjct: 171 QYCHQKYIVHRDLKAENLLL-----------DGDMNIKIADFGFSNEFTVGNKLDTFCGS 219
Query: 693 PMYMAPEV 716
P Y APE+
Sbjct: 220 PPYAAPEL 227
>AL592406-3|CAH72463.1| 795|Homo sapiens MAP/microtubule
affinity-regulating kinase 1 protein.
Length = 795
Score = 109 bits (262), Expect = 1e-23
Identities = 67/188 (35%), Positives = 102/188 (54%), Gaps = 1/188 (0%)
Frame = +3
Query: 156 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKILRE 332
+G+Y K IG G FA V K + + VAVK++ K + S + L +E++I++
Sbjct: 57 IGNYRLQKT--IGKGNFAKV-KLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMK- 112
Query: 333 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 512
L H N+V + + +++ +Y+VMEY +GG++ DYL + + E + Q+ A+
Sbjct: 113 --ILNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAV 170
Query: 513 SAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGS 692
H K IVHRDLK +N+LL D+ +KIADFGF+ GN T CGS
Sbjct: 171 QYCHQKYIVHRDLKAENLLL-----------DGDMNIKIADFGFSNEFTVGNKLDTFCGS 219
Query: 693 PMYMAPEV 716
P Y APE+
Sbjct: 220 PPYAAPEL 227
>AF154845-1|AAF72103.1| 795|Homo sapiens MARK protein.
Length = 795
Score = 109 bits (262), Expect = 1e-23
Identities = 67/188 (35%), Positives = 102/188 (54%), Gaps = 1/188 (0%)
Frame = +3
Query: 156 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKILRE 332
+G+Y K IG G FA V K + + VAVK++ K + S + L +E++I++
Sbjct: 57 IGNYRLQKT--IGKGNFAKV-KLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMK- 112
Query: 333 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 512
L H N+V + + +++ +Y+VMEY +GG++ DYL + + E + Q+ A+
Sbjct: 113 --ILNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAV 170
Query: 513 SAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGS 692
H K IVHRDLK +N+LL D+ +KIADFGF+ GN T CGS
Sbjct: 171 QYCHQKYIVHRDLKAENLLL-----------DGDMNIKIADFGFSNEFTVGNKLDTFCGS 219
Query: 693 PMYMAPEV 716
P Y APE+
Sbjct: 220 PPYAAPEL 227
>CR456418-1|CAG30304.1| 586|Homo sapiens CHEK2 protein.
Length = 586
Score = 108 bits (260), Expect = 2e-23
Identities = 67/194 (34%), Positives = 109/194 (56%), Gaps = 7/194 (3%)
Frame = +3
Query: 168 EFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKK--GIQKASEI-----LVKEIKIL 326
E+ +G GA V +RK + VA+K+++K+ I A E + EI+IL
Sbjct: 262 EYIMSKTLGSGACGEVKLAFERKT-CKKVAIKIISKRKFAIGSAREADPALNVETEIEIL 320
Query: 327 RELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAE 506
++L H ++ + + D+ Y Y+V+E GG+L D + N+ L E T +L+ Q+
Sbjct: 321 KKLN---HPCIIKIKNFFDAEDY-YIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLL 376
Query: 507 AMSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLC 686
A+ +H GI+HRDLKP+N+LL + D +KI DFG ++ L E ++ TLC
Sbjct: 377 AVQYLHENGIIHRDLKPENVLL--------SSQEEDCLIKITDFGHSKILGETSLMRTLC 428
Query: 687 GSPMYMAPEVIMSL 728
G+P Y+APEV++S+
Sbjct: 429 GTPTYLAPEVLVSV 442
>BC035745-1|AAH35745.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 108 bits (260), Expect = 2e-23
Identities = 61/183 (33%), Positives = 105/183 (57%)
Frame = +3
Query: 171 FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQH 350
F ++ +G GAF+ V + K + AVK + KK ++ + EI +LR++ +H
Sbjct: 23 FEFKETLGTGAFSEVVLAEE-KATGKLFAVKCIPKKALKGKESSIENEIAVLRKI---KH 78
Query: 351 KNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAK 530
+N+VA+ D +SP ++Y+VM+ +GG+L D + +E + Q+ +A+ +H
Sbjct: 79 ENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRM 138
Query: 531 GIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYMAP 710
GIVHRDLKP+N LL +S + + I+DFG ++ +G++ T CG+P Y+AP
Sbjct: 139 GIVHRDLKPEN-LLYYS-------QDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAP 190
Query: 711 EVI 719
EV+
Sbjct: 191 EVL 193
>BC004207-1|AAH04207.1| 543|Homo sapiens CHK2 checkpoint homolog
(S. pombe) protein.
Length = 543
Score = 108 bits (260), Expect = 2e-23
Identities = 67/194 (34%), Positives = 109/194 (56%), Gaps = 7/194 (3%)
Frame = +3
Query: 168 EFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKK--GIQKASEI-----LVKEIKIL 326
E+ +G GA V +RK + VA+K+++K+ I A E + EI+IL
Sbjct: 219 EYIMSKTLGSGACGEVKLAFERKT-CKKVAIKIISKRKFAIGSAREADPALNVETEIEIL 277
Query: 327 RELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAE 506
++L H ++ + + D+ Y Y+V+E GG+L D + N+ L E T +L+ Q+
Sbjct: 278 KKLN---HPCIIKIKNFFDAEDY-YIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLL 333
Query: 507 AMSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLC 686
A+ +H GI+HRDLKP+N+LL + D +KI DFG ++ L E ++ TLC
Sbjct: 334 AVQYLHENGIIHRDLKPENVLL--------SSQEEDCLIKITDFGHSKILGETSLMRTLC 385
Query: 687 GSPMYMAPEVIMSL 728
G+P Y+APEV++S+
Sbjct: 386 GTPTYLAPEVLVSV 399
>AY800241-1|AAV41895.1| 543|Homo sapiens CHK2 checkpoint homolog
(S. pombe) protein.
Length = 543
Score = 108 bits (260), Expect = 2e-23
Identities = 67/194 (34%), Positives = 109/194 (56%), Gaps = 7/194 (3%)
Frame = +3
Query: 168 EFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKK--GIQKASEI-----LVKEIKIL 326
E+ +G GA V +RK + VA+K+++K+ I A E + EI+IL
Sbjct: 219 EYIMSKTLGSGACGEVKLAFERKT-CKKVAIKIISKRKFAIGSAREADPALNVETEIEIL 277
Query: 327 RELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAE 506
++L H ++ + + D+ Y Y+V+E GG+L D + N+ L E T +L+ Q+
Sbjct: 278 KKLN---HPCIIKIKNFFDAEDY-YIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLL 333
Query: 507 AMSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLC 686
A+ +H GI+HRDLKP+N+LL + D +KI DFG ++ L E ++ TLC
Sbjct: 334 AVQYLHENGIIHRDLKPENVLL--------SSQEEDCLIKITDFGHSKILGETSLMRTLC 385
Query: 687 GSPMYMAPEVIMSL 728
G+P Y+APEV++S+
Sbjct: 386 GTPTYLAPEVLVSV 399
>AY551303-1|AAS58464.1| 452|Homo sapiens protein kinase Chk2
transcript variant del2-3 protein.
Length = 452
Score = 108 bits (260), Expect = 2e-23
Identities = 67/194 (34%), Positives = 109/194 (56%), Gaps = 7/194 (3%)
Frame = +3
Query: 168 EFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKK--GIQKASEI-----LVKEIKIL 326
E+ +G GA V +RK + VA+K+++K+ I A E + EI+IL
Sbjct: 128 EYIMSKTLGSGACGEVKLAFERKT-CKKVAIKIISKRKFAIGSAREADPALNVETEIEIL 186
Query: 327 RELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAE 506
++L H ++ + + D+ Y Y+V+E GG+L D + N+ L E T +L+ Q+
Sbjct: 187 KKLN---HPCIIKIKNFFDAEDY-YIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLL 242
Query: 507 AMSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLC 686
A+ +H GI+HRDLKP+N+LL + D +KI DFG ++ L E ++ TLC
Sbjct: 243 AVQYLHENGIIHRDLKPENVLL--------SSQEEDCLIKITDFGHSKILGETSLMRTLC 294
Query: 687 GSPMYMAPEVIMSL 728
G+P Y+APEV++S+
Sbjct: 295 GTPTYLAPEVLVSV 308
>AY551297-1|AAS58458.1| 586|Homo sapiens protein kinase Chk2
transcript variant insX protein.
Length = 586
Score = 108 bits (260), Expect = 2e-23
Identities = 67/194 (34%), Positives = 109/194 (56%), Gaps = 7/194 (3%)
Frame = +3
Query: 168 EFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKK--GIQKASEI-----LVKEIKIL 326
E+ +G GA V +RK + VA+K+++K+ I A E + EI+IL
Sbjct: 262 EYIMSKTLGSGACGEVKLAFERKT-CKKVAIKIISKRKFAIGSAREADPALNVETEIEIL 320
Query: 327 RELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAE 506
++L H ++ + + D+ Y Y+V+E GG+L D + N+ L E T +L+ Q+
Sbjct: 321 KKLN---HPCIIKIKNFFDAEDY-YIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLL 376
Query: 507 AMSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLC 686
A+ +H GI+HRDLKP+N+LL + D +KI DFG ++ L E ++ TLC
Sbjct: 377 AVQYLHENGIIHRDLKPENVLL--------SSQEEDCLIKITDFGHSKILGETSLMRTLC 428
Query: 687 GSPMYMAPEVIMSL 728
G+P Y+APEV++S+
Sbjct: 429 GTPTYLAPEVLVSV 442
>AL731559-2|CAI14675.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 108 bits (260), Expect = 2e-23
Identities = 61/183 (33%), Positives = 105/183 (57%)
Frame = +3
Query: 171 FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQH 350
F ++ +G GAF+ V + K + AVK + KK ++ + EI +LR++ +H
Sbjct: 23 FEFKETLGTGAFSEVVLAEE-KATGKLFAVKCIPKKALKGKESSIENEIAVLRKI---KH 78
Query: 351 KNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAK 530
+N+VA+ D +SP ++Y+VM+ +GG+L D + +E + Q+ +A+ +H
Sbjct: 79 ENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRM 138
Query: 531 GIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYMAP 710
GIVHRDLKP+N LL +S + + I+DFG ++ +G++ T CG+P Y+AP
Sbjct: 139 GIVHRDLKPEN-LLYYS-------QDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAP 190
Query: 711 EVI 719
EV+
Sbjct: 191 EVL 193
>AL731559-1|CAI14674.1| 357|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 357
Score = 108 bits (260), Expect = 2e-23
Identities = 61/183 (33%), Positives = 105/183 (57%)
Frame = +3
Query: 171 FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQH 350
F ++ +G GAF+ V + K + AVK + KK ++ + EI +LR++ +H
Sbjct: 23 FEFKETLGTGAFSEVVLAEE-KATGKLFAVKCIPKKALKGKESSIENEIAVLRKI---KH 78
Query: 351 KNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAK 530
+N+VA+ D +SP ++Y+VM+ +GG+L D + +E + Q+ +A+ +H
Sbjct: 79 ENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRM 138
Query: 531 GIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYMAP 710
GIVHRDLKP+N LL +S + + I+DFG ++ +G++ T CG+P Y+AP
Sbjct: 139 GIVHRDLKPEN-LLYYS-------QDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAP 190
Query: 711 EVI 719
EV+
Sbjct: 191 EVL 193
>AL512783-2|CAH74036.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 108 bits (260), Expect = 2e-23
Identities = 61/183 (33%), Positives = 105/183 (57%)
Frame = +3
Query: 171 FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQH 350
F ++ +G GAF+ V + K + AVK + KK ++ + EI +LR++ +H
Sbjct: 23 FEFKETLGTGAFSEVVLAEE-KATGKLFAVKCIPKKALKGKESSIENEIAVLRKI---KH 78
Query: 351 KNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAK 530
+N+VA+ D +SP ++Y+VM+ +GG+L D + +E + Q+ +A+ +H
Sbjct: 79 ENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRM 138
Query: 531 GIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYMAP 710
GIVHRDLKP+N LL +S + + I+DFG ++ +G++ T CG+P Y+AP
Sbjct: 139 GIVHRDLKPEN-LLYYS-------QDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAP 190
Query: 711 EVI 719
EV+
Sbjct: 191 EVL 193
>AL512783-1|CAH74035.1| 357|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 357
Score = 108 bits (260), Expect = 2e-23
Identities = 61/183 (33%), Positives = 105/183 (57%)
Frame = +3
Query: 171 FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQH 350
F ++ +G GAF+ V + K + AVK + KK ++ + EI +LR++ +H
Sbjct: 23 FEFKETLGTGAFSEVVLAEE-KATGKLFAVKCIPKKALKGKESSIENEIAVLRKI---KH 78
Query: 351 KNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAK 530
+N+VA+ D +SP ++Y+VM+ +GG+L D + +E + Q+ +A+ +H
Sbjct: 79 ENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRM 138
Query: 531 GIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYMAP 710
GIVHRDLKP+N LL +S + + I+DFG ++ +G++ T CG+P Y+AP
Sbjct: 139 GIVHRDLKPEN-LLYYS-------QDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAP 190
Query: 711 EVI 719
EV+
Sbjct: 191 EVL 193
>AL512284-2|CAH71694.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 108 bits (260), Expect = 2e-23
Identities = 61/183 (33%), Positives = 105/183 (57%)
Frame = +3
Query: 171 FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQH 350
F ++ +G GAF+ V + K + AVK + KK ++ + EI +LR++ +H
Sbjct: 23 FEFKETLGTGAFSEVVLAEE-KATGKLFAVKCIPKKALKGKESSIENEIAVLRKI---KH 78
Query: 351 KNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAK 530
+N+VA+ D +SP ++Y+VM+ +GG+L D + +E + Q+ +A+ +H
Sbjct: 79 ENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRM 138
Query: 531 GIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYMAP 710
GIVHRDLKP+N LL +S + + I+DFG ++ +G++ T CG+P Y+AP
Sbjct: 139 GIVHRDLKPEN-LLYYS-------QDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAP 190
Query: 711 EVI 719
EV+
Sbjct: 191 EVL 193
>AL512284-1|CAH71693.1| 357|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 357
Score = 108 bits (260), Expect = 2e-23
Identities = 61/183 (33%), Positives = 105/183 (57%)
Frame = +3
Query: 171 FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQH 350
F ++ +G GAF+ V + K + AVK + KK ++ + EI +LR++ +H
Sbjct: 23 FEFKETLGTGAFSEVVLAEE-KATGKLFAVKCIPKKALKGKESSIENEIAVLRKI---KH 78
Query: 351 KNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAK 530
+N+VA+ D +SP ++Y+VM+ +GG+L D + +E + Q+ +A+ +H
Sbjct: 79 ENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRM 138
Query: 531 GIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYMAP 710
GIVHRDLKP+N LL +S + + I+DFG ++ +G++ T CG+P Y+AP
Sbjct: 139 GIVHRDLKPEN-LLYYS-------QDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAP 190
Query: 711 EVI 719
EV+
Sbjct: 191 EVL 193
>AL391314-2|CAI14410.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 108 bits (260), Expect = 2e-23
Identities = 61/183 (33%), Positives = 105/183 (57%)
Frame = +3
Query: 171 FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQH 350
F ++ +G GAF+ V + K + AVK + KK ++ + EI +LR++ +H
Sbjct: 23 FEFKETLGTGAFSEVVLAEE-KATGKLFAVKCIPKKALKGKESSIENEIAVLRKI---KH 78
Query: 351 KNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAK 530
+N+VA+ D +SP ++Y+VM+ +GG+L D + +E + Q+ +A+ +H
Sbjct: 79 ENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRM 138
Query: 531 GIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYMAP 710
GIVHRDLKP+N LL +S + + I+DFG ++ +G++ T CG+P Y+AP
Sbjct: 139 GIVHRDLKPEN-LLYYS-------QDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAP 190
Query: 711 EVI 719
EV+
Sbjct: 191 EVL 193
>AL391314-1|CAI14409.1| 357|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 357
Score = 108 bits (260), Expect = 2e-23
Identities = 61/183 (33%), Positives = 105/183 (57%)
Frame = +3
Query: 171 FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQH 350
F ++ +G GAF+ V + K + AVK + KK ++ + EI +LR++ +H
Sbjct: 23 FEFKETLGTGAFSEVVLAEE-KATGKLFAVKCIPKKALKGKESSIENEIAVLRKI---KH 78
Query: 351 KNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAK 530
+N+VA+ D +SP ++Y+VM+ +GG+L D + +E + Q+ +A+ +H
Sbjct: 79 ENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRM 138
Query: 531 GIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYMAP 710
GIVHRDLKP+N LL +S + + I+DFG ++ +G++ T CG+P Y+AP
Sbjct: 139 GIVHRDLKPEN-LLYYS-------QDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAP 190
Query: 711 EVI 719
EV+
Sbjct: 191 EVL 193
>AL121825-1|CAH73823.1| 543|Homo sapiens CHK2 checkpoint homolog
(S. pombe) protein.
Length = 543
Score = 108 bits (260), Expect = 2e-23
Identities = 67/194 (34%), Positives = 109/194 (56%), Gaps = 7/194 (3%)
Frame = +3
Query: 168 EFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKK--GIQKASEI-----LVKEIKIL 326
E+ +G GA V +RK + VA+K+++K+ I A E + EI+IL
Sbjct: 219 EYIMSKTLGSGACGEVKLAFERKT-CKKVAIKIISKRKFAIGSAREADPALNVETEIEIL 277
Query: 327 RELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAE 506
++L H ++ + + D+ Y Y+V+E GG+L D + N+ L E T +L+ Q+
Sbjct: 278 KKLN---HPCIIKIKNFFDAEDY-YIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLL 333
Query: 507 AMSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLC 686
A+ +H GI+HRDLKP+N+LL + D +KI DFG ++ L E ++ TLC
Sbjct: 334 AVQYLHENGIIHRDLKPENVLL--------SSQEEDCLIKITDFGHSKILGETSLMRTLC 385
Query: 687 GSPMYMAPEVIMSL 728
G+P Y+APEV++S+
Sbjct: 386 GTPTYLAPEVLVSV 399
>AL117330-1|CAH73875.1| 543|Homo sapiens CHK2 checkpoint homolog
(S. pombe) protein.
Length = 543
Score = 108 bits (260), Expect = 2e-23
Identities = 67/194 (34%), Positives = 109/194 (56%), Gaps = 7/194 (3%)
Frame = +3
Query: 168 EFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKK--GIQKASEI-----LVKEIKIL 326
E+ +G GA V +RK + VA+K+++K+ I A E + EI+IL
Sbjct: 219 EYIMSKTLGSGACGEVKLAFERKT-CKKVAIKIISKRKFAIGSAREADPALNVETEIEIL 277
Query: 327 RELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAE 506
++L H ++ + + D+ Y Y+V+E GG+L D + N+ L E T +L+ Q+
Sbjct: 278 KKLN---HPCIIKIKNFFDAEDY-YIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLL 333
Query: 507 AMSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLC 686
A+ +H GI+HRDLKP+N+LL + D +KI DFG ++ L E ++ TLC
Sbjct: 334 AVQYLHENGIIHRDLKPENVLL--------SSQEEDCLIKITDFGHSKILGETSLMRTLC 385
Query: 687 GSPMYMAPEVIMSL 728
G+P Y+APEV++S+
Sbjct: 386 GTPTYLAPEVLVSV 399
>AJ131197-1|CAA10319.1| 543|Homo sapiens protein kinase protein.
Length = 543
Score = 108 bits (260), Expect = 2e-23
Identities = 67/194 (34%), Positives = 109/194 (56%), Gaps = 7/194 (3%)
Frame = +3
Query: 168 EFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKK--GIQKASEI-----LVKEIKIL 326
E+ +G GA V +RK + VA+K+++K+ I A E + EI+IL
Sbjct: 219 EYIMSKTLGSGACGEVKLAFERKT-CKKVAIKIISKRKFAIGSAREADPALNVETEIEIL 277
Query: 327 RELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAE 506
++L H ++ + + D+ Y Y+V+E GG+L D + N+ L E T +L+ Q+
Sbjct: 278 KKLN---HPCIIKIKNFFDAEDY-YIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLL 333
Query: 507 AMSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLC 686
A+ +H GI+HRDLKP+N+LL + D +KI DFG ++ L E ++ TLC
Sbjct: 334 AVQYLHENGIIHRDLKPENVLL--------SSQEEDCLIKITDFGHSKILGETSLMRTLC 385
Query: 687 GSPMYMAPEVIMSL 728
G+P Y+APEV++S+
Sbjct: 386 GTPTYLAPEVLVSV 399
>AF286366-1|AAG00534.1| 357|Homo sapiens CamKI-like protein kinase
protein.
Length = 357
Score = 108 bits (260), Expect = 2e-23
Identities = 61/183 (33%), Positives = 105/183 (57%)
Frame = +3
Query: 171 FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQH 350
F ++ +G GAF+ V + K + AVK + KK ++ + EI +LR++ +H
Sbjct: 23 FEFKETLGTGAFSEVVLAEE-KATGKLFAVKCIPKKALKGKESSIENEIAVLRKI---KH 78
Query: 351 KNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAK 530
+N+VA+ D +SP ++Y+VM+ +GG+L D + +E + Q+ +A+ +H
Sbjct: 79 ENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRM 138
Query: 531 GIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYMAP 710
GIVHRDLKP+N LL +S + + I+DFG ++ +G++ T CG+P Y+AP
Sbjct: 139 GIVHRDLKPEN-LLYYS-------QDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAP 190
Query: 711 EVI 719
EV+
Sbjct: 191 EVL 193
>AF174135-1|AAD48504.1| 543|Homo sapiens protein kinase CHK2
protein.
Length = 543
Score = 108 bits (260), Expect = 2e-23
Identities = 67/194 (34%), Positives = 109/194 (56%), Gaps = 7/194 (3%)
Frame = +3
Query: 168 EFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKK--GIQKASEI-----LVKEIKIL 326
E+ +G GA V +RK + VA+K+++K+ I A E + EI+IL
Sbjct: 219 EYIMSKTLGSGACGEVKLAFERKT-CKKVAIKIISKRKFAIGSAREADPALNVETEIEIL 277
Query: 327 RELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAE 506
++L H ++ + + D+ Y Y+V+E GG+L D + N+ L E T +L+ Q+
Sbjct: 278 KKLN---HPCIIKIKNFFDAEDY-YIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLL 333
Query: 507 AMSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLC 686
A+ +H GI+HRDLKP+N+LL + D +KI DFG ++ L E ++ TLC
Sbjct: 334 AVQYLHENGIIHRDLKPENVLL--------SSQEEDCLIKITDFGHSKILGETSLMRTLC 385
Query: 687 GSPMYMAPEVIMSL 728
G+P Y+APEV++S+
Sbjct: 386 GTPTYLAPEVLVSV 399
>AF096279-1|AAD11784.1| 543|Homo sapiens HuCds1 kinase protein.
Length = 543
Score = 108 bits (260), Expect = 2e-23
Identities = 67/194 (34%), Positives = 109/194 (56%), Gaps = 7/194 (3%)
Frame = +3
Query: 168 EFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKK--GIQKASEI-----LVKEIKIL 326
E+ +G GA V +RK + VA+K+++K+ I A E + EI+IL
Sbjct: 219 EYIMSKTLGSGACGEVKLAFERKT-CKKVAIKIISKRKFAIGSAREADPALNVETEIEIL 277
Query: 327 RELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAE 506
++L H ++ + + D+ Y Y+V+E GG+L D + N+ L E T +L+ Q+
Sbjct: 278 KKLN---HPCIIKIKNFFDAEDY-YIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLL 333
Query: 507 AMSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLC 686
A+ +H GI+HRDLKP+N+LL + D +KI DFG ++ L E ++ TLC
Sbjct: 334 AVQYLHENGIIHRDLKPENVLL--------SSQEEDCLIKITDFGHSKILGETSLMRTLC 385
Query: 687 GSPMYMAPEVIMSL 728
G+P Y+APEV++S+
Sbjct: 386 GTPTYLAPEVLVSV 399
>AF086904-1|AAC83693.1| 543|Homo sapiens protein kinase Chk2
protein.
Length = 543
Score = 108 bits (260), Expect = 2e-23
Identities = 67/194 (34%), Positives = 109/194 (56%), Gaps = 7/194 (3%)
Frame = +3
Query: 168 EFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKK--GIQKASEI-----LVKEIKIL 326
E+ +G GA V +RK + VA+K+++K+ I A E + EI+IL
Sbjct: 219 EYIMSKTLGSGACGEVKLAFERKT-CKKVAIKIISKRKFAIGSAREADPALNVETEIEIL 277
Query: 327 RELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAE 506
++L H ++ + + D+ Y Y+V+E GG+L D + N+ L E T +L+ Q+
Sbjct: 278 KKLN---HPCIIKIKNFFDAEDY-YIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLL 333
Query: 507 AMSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLC 686
A+ +H GI+HRDLKP+N+LL + D +KI DFG ++ L E ++ TLC
Sbjct: 334 AVQYLHENGIIHRDLKPENVLL--------SSQEEDCLIKITDFGHSKILGETSLMRTLC 385
Query: 687 GSPMYMAPEVIMSL 728
G+P Y+APEV++S+
Sbjct: 386 GTPTYLAPEVLVSV 399
>AB081726-1|BAC19846.1| 385|Homo sapiens CaM-kinase I delta
protein.
Length = 385
Score = 108 bits (260), Expect = 2e-23
Identities = 61/183 (33%), Positives = 105/183 (57%)
Frame = +3
Query: 171 FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQH 350
F ++ +G GAF+ V + K + AVK + KK ++ + EI +LR++ +H
Sbjct: 23 FEFKETLGTGAFSEVVLAEE-KATGKLFAVKCIPKKALKGKESSIENEIAVLRKI---KH 78
Query: 351 KNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAK 530
+N+VA+ D +SP ++Y+VM+ +GG+L D + +E + Q+ +A+ +H
Sbjct: 79 ENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRM 138
Query: 531 GIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYMAP 710
GIVHRDLKP+N LL +S + + I+DFG ++ +G++ T CG+P Y+AP
Sbjct: 139 GIVHRDLKPEN-LLYYS-------QDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAP 190
Query: 711 EVI 719
EV+
Sbjct: 191 EVL 193
>BC017306-1|AAH17306.1| 628|Homo sapiens NUAK family, SNF1-like
kinase, 2 protein.
Length = 628
Score = 108 bits (259), Expect = 2e-23
Identities = 61/187 (32%), Positives = 105/187 (56%), Gaps = 2/187 (1%)
Frame = +3
Query: 165 YEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILV--KEIKILRELT 338
YEF + +G G + V K R+ + + VA+K + K I+ +++ +EI+I+ +
Sbjct: 53 YEFL--ETLGKGTYGKVKKARE--SSGRLVAIKSIRKDKIKDEQDLMHIRREIEIM---S 105
Query: 339 ALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSA 518
+L H +++A+H+ ++ + + +VMEY + GDL DY+ + LSE + F Q+ A+
Sbjct: 106 SLNHPHIIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHY 165
Query: 519 IHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPM 698
H +VHRDLK +NILL ++ +KIADFG + +G T CGSP+
Sbjct: 166 CHQNRVVHRDLKLENILL-----------DANGNIKIADFGLSNLYHQGKFLQTFCGSPL 214
Query: 699 YMAPEVI 719
Y +PE++
Sbjct: 215 YASPEIV 221
>AK074830-1|BAC11234.1| 628|Homo sapiens protein ( Homo sapiens
cDNA FLJ90349 fis, clone NT2RP2003179, weakly similar to
PUTATIVE SERINE/THREONINE-PROTEIN KINASE EMK (EC
2.7.1.-). ).
Length = 628
Score = 108 bits (259), Expect = 2e-23
Identities = 61/187 (32%), Positives = 105/187 (56%), Gaps = 2/187 (1%)
Frame = +3
Query: 165 YEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILV--KEIKILRELT 338
YEF + +G G + V K R+ + + VA+K + K I+ +++ +EI+I+ +
Sbjct: 53 YEFL--ETLGKGTYGKVKKARE--SSGRLVAIKSIRKDKIKDEQDLMHIRREIEIM---S 105
Query: 339 ALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSA 518
+L H +++A+H+ ++ + + +VMEY + GDL DY+ + LSE + F Q+ A+
Sbjct: 106 SLNHPHIIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHY 165
Query: 519 IHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPM 698
H +VHRDLK +NILL ++ +KIADFG + +G T CGSP+
Sbjct: 166 CHQNRVVHRDLKLENILL-----------DANGNIKIADFGLSNLYHQGKFLQTFCGSPL 214
Query: 699 YMAPEVI 719
Y +PE++
Sbjct: 215 YASPEIV 221
>L41816-1|AAA99458.1| 370|Homo sapiens cam kinase I protein.
Length = 370
Score = 107 bits (258), Expect = 3e-23
Identities = 59/185 (31%), Positives = 107/185 (57%)
Frame = +3
Query: 165 YEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTAL 344
Y+F +D++G GAF+ V ++ + VA+K + K+ ++ + EI +L ++
Sbjct: 20 YDF--RDVLGTGAFSEVILAEDKRT-QKLVAIKCIAKEALEGKEGSMENEIAVLHKI--- 73
Query: 345 QHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIH 524
+H N+VA+ D +S ++Y++M+ +GG+L D + +E + Q+ +A+ +H
Sbjct: 74 KHPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLH 133
Query: 525 AKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYM 704
GIVHRDLKP+N LL +S+ D + I+DFG ++ + G++ T CG+P Y+
Sbjct: 134 DLGIVHRDLKPEN-LLYYSL-------DEDSKIMISDFGLSKMEDPGSVLSTACGTPGYV 185
Query: 705 APEVI 719
APEV+
Sbjct: 186 APEVL 190
>BC106755-1|AAI06756.1| 370|Homo sapiens
calcium/calmodulin-dependent protein kinase I protein.
Length = 370
Score = 107 bits (258), Expect = 3e-23
Identities = 59/185 (31%), Positives = 107/185 (57%)
Frame = +3
Query: 165 YEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTAL 344
Y+F +D++G GAF+ V ++ + VA+K + K+ ++ + EI +L ++
Sbjct: 20 YDF--RDVLGTGAFSEVILAEDKRT-QKLVAIKCIAKEALEGKEGSMENEIAVLHKI--- 73
Query: 345 QHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIH 524
+H N+VA+ D +S ++Y++M+ +GG+L D + +E + Q+ +A+ +H
Sbjct: 74 KHPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLH 133
Query: 525 AKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYM 704
GIVHRDLKP+N LL +S+ D + I+DFG ++ + G++ T CG+P Y+
Sbjct: 134 DLGIVHRDLKPEN-LLYYSL-------DEDSKIMISDFGLSKMEDPGSVLSTACGTPGYV 185
Query: 705 APEVI 719
APEV+
Sbjct: 186 APEVL 190
>BC106754-1|AAI06755.1| 370|Homo sapiens
calcium/calmodulin-dependent protein kinase I protein.
Length = 370
Score = 107 bits (258), Expect = 3e-23
Identities = 59/185 (31%), Positives = 107/185 (57%)
Frame = +3
Query: 165 YEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTAL 344
Y+F +D++G GAF+ V ++ + VA+K + K+ ++ + EI +L ++
Sbjct: 20 YDF--RDVLGTGAFSEVILAEDKRT-QKLVAIKCIAKEALEGKEGSMENEIAVLHKI--- 73
Query: 345 QHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIH 524
+H N+VA+ D +S ++Y++M+ +GG+L D + +E + Q+ +A+ +H
Sbjct: 74 KHPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLH 133
Query: 525 AKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYM 704
GIVHRDLKP+N LL +S+ D + I+DFG ++ + G++ T CG+P Y+
Sbjct: 134 DLGIVHRDLKPEN-LLYYSL-------DEDSKIMISDFGLSKMEDPGSVLSTACGTPGYV 185
Query: 705 APEVI 719
APEV+
Sbjct: 186 APEVL 190
>AF217975-1|AAG17218.1| 322|Homo sapiens unknown protein.
Length = 322
Score = 107 bits (256), Expect = 5e-23
Identities = 66/187 (35%), Positives = 107/187 (57%), Gaps = 7/187 (3%)
Frame = +3
Query: 189 IGHGAFAMVYKGRKRKNPSQSVAVKVVTKK--GIQKASEI-----LVKEIKILRELTALQ 347
+G GA V +RK + VA+K+++K+ I A E + EI+IL++L
Sbjct: 5 LGSGACGEVKLAFERKT-CKKVAIKIISKRKFAIGSAREADPALNVETEIEILKKLN--- 60
Query: 348 HKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHA 527
H ++ + + D+ Y Y+V+E GG+L D + N+ L E T +L+ Q+ A+ +H
Sbjct: 61 HPCIIKIKNFFDAEDY-YIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLLAVQYLHE 119
Query: 528 KGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYMA 707
GI+HRDLKP+N+LL + D +KI DFG ++ L E ++ TLCG+P Y+A
Sbjct: 120 NGIIHRDLKPENVLL--------SSQEEDCLIKITDFGHSKILGETSLMRTLCGTPTYLA 171
Query: 708 PEVIMSL 728
PEV++S+
Sbjct: 172 PEVLVSV 178
>L24959-1|AAA18251.1| 473|Homo sapiens calcium/calmodulin dependent
protein kinase protein.
Length = 473
Score = 106 bits (255), Expect = 7e-23
Identities = 65/183 (35%), Positives = 105/183 (57%)
Frame = +3
Query: 171 FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQH 350
F + +G GA ++VY+ K+K + A+KV+ KK + K +I+ EI +L L+ H
Sbjct: 46 FEVESELGRGATSIVYRC-KQKGTQKPYALKVL-KKTVDK--KIVRTEIGVLLRLS---H 98
Query: 351 KNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAK 530
N++ + + ++P + +V+E GG+L D + SE + Q+ EA++ +H
Sbjct: 99 PNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHEN 158
Query: 531 GIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYMAP 710
GIVHRDLKP+N+L TP P D LKIADFG ++ +E + T+CG+P Y AP
Sbjct: 159 GIVHRDLKPENLLYA-------TPAP-DAPLKIADFGLSKIVEHQVLMKTVCGTPGYCAP 210
Query: 711 EVI 719
E++
Sbjct: 211 EIL 213
>L17000-1|AAA35639.1| 473|Homo sapiens calcium/calmodulin-dependent
protein kinase protein.
Length = 473
Score = 106 bits (255), Expect = 7e-23
Identities = 65/183 (35%), Positives = 105/183 (57%)
Frame = +3
Query: 171 FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQH 350
F + +G GA ++VY+ K+K + A+KV+ KK + K +I+ EI +L L+ H
Sbjct: 46 FEVESELGRGATSIVYRC-KQKGTQKPYALKVL-KKTVDK--KIVRTEIGVLLRLS---H 98
Query: 351 KNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAK 530
N++ + + ++P + +V+E GG+L D + SE + Q+ EA++ +H
Sbjct: 99 PNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHEN 158
Query: 531 GIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYMAP 710
GIVHRDLKP+N+L TP P D LKIADFG ++ +E + T+CG+P Y AP
Sbjct: 159 GIVHRDLKPENLLYA-------TPAP-DAPLKIADFGLSKIVEHQVLMKTVCGTPGYCAP 210
Query: 711 EVI 719
E++
Sbjct: 211 EIL 213
>D30742-1|BAA06403.1| 473|Homo sapiens calmodulin-dependent protein
kinase IV protein.
Length = 473
Score = 106 bits (255), Expect = 7e-23
Identities = 65/183 (35%), Positives = 105/183 (57%)
Frame = +3
Query: 171 FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQH 350
F + +G GA ++VY+ K+K + A+KV+ KK + K +I+ EI +L L+ H
Sbjct: 46 FEVESELGRGATSIVYRC-KQKGTQKPYALKVL-KKTVDK--KIVRTEIGVLLRLS---H 98
Query: 351 KNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAK 530
N++ + + ++P + +V+E GG+L D + SE + Q+ EA++ +H
Sbjct: 99 PNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHEN 158
Query: 531 GIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYMAP 710
GIVHRDLKP+N+L TP P D LKIADFG ++ +E + T+CG+P Y AP
Sbjct: 159 GIVHRDLKPENLLYA-------TPAP-DAPLKIADFGLSKIVEHQVLMKTVCGTPGYCAP 210
Query: 711 EVI 719
E++
Sbjct: 211 EIL 213
>BC126432-1|AAI26433.1| 454|Homo sapiens death-associated protein
kinase 3 protein.
Length = 454
Score = 106 bits (255), Expect = 7e-23
Identities = 60/182 (32%), Positives = 102/182 (56%), Gaps = 5/182 (2%)
Frame = +3
Query: 189 IGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-----EILVKEIKILRELTALQHK 353
+G G FA+V K R+ K + A K + K+ + + E + +E+ ILRE+ +H
Sbjct: 19 LGSGQFAIVRKCRQ-KGTGKEYAAKFIKKRRLSSSRRGVSREEIEREVNILREI---RHP 74
Query: 354 NLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKG 533
N++ +HD ++ V +++E +GG+L D+L L+E FL Q+ + + +H+K
Sbjct: 75 NIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLHSKR 134
Query: 534 IVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYMAPE 713
I H DLKP+NI+L L P+P +K+ DFG A +E GN + G+P ++APE
Sbjct: 135 IAHFDLKPENIML----LDKNVPNP---RIKLIDFGIAHKIEAGNEFKNIFGTPEFVAPE 187
Query: 714 VI 719
++
Sbjct: 188 IV 189
>BC126430-1|AAI26431.1| 454|Homo sapiens death-associated protein
kinase 3 protein.
Length = 454
Score = 106 bits (255), Expect = 7e-23
Identities = 60/182 (32%), Positives = 102/182 (56%), Gaps = 5/182 (2%)
Frame = +3
Query: 189 IGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-----EILVKEIKILRELTALQHK 353
+G G FA+V K R+ K + A K + K+ + + E + +E+ ILRE+ +H
Sbjct: 19 LGSGQFAIVRKCRQ-KGTGKEYAAKFIKKRRLSSSRRGVSREEIEREVNILREI---RHP 74
Query: 354 NLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKG 533
N++ +HD ++ V +++E +GG+L D+L L+E FL Q+ + + +H+K
Sbjct: 75 NIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLHSKR 134
Query: 534 IVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYMAPE 713
I H DLKP+NI+L L P+P +K+ DFG A +E GN + G+P ++APE
Sbjct: 135 IAHFDLKPENIML----LDKNVPNP---RIKLIDFGIAHKIEAGNEFKNIFGTPEFVAPE 187
Query: 714 VI 719
++
Sbjct: 188 IV 189
>BC037303-1|AAH37303.1| 550|Homo sapiens PRKAA1 protein protein.
Length = 550
Score = 106 bits (255), Expect = 7e-23
Identities = 60/190 (31%), Positives = 103/190 (54%)
Frame = +3
Query: 150 IQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILR 329
+++G Y D +G G F V G K + VAVK++ ++ I ++ +++ K + ++
Sbjct: 13 VKIGHYILG--DTLGVGTFGKVKVG-KHELTGHKVAVKILNRQKI-RSLDVVGKIRREIQ 68
Query: 330 ELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEA 509
L +H +++ ++ + +P+ +++VMEY +GG+L DY+ N L E + Q+
Sbjct: 69 NLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSG 128
Query: 510 MSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCG 689
+ H +VHRDLKP+N+LL + + KIADFG + + +G T CG
Sbjct: 129 VDYCHRHMVVHRDLKPENVLL-----------DAHMNAKIADFGLSNMMSDGEFLRTSCG 177
Query: 690 SPMYMAPEVI 719
SP Y APEVI
Sbjct: 178 SPNYAAPEVI 187
>BC025687-1|AAH25687.1| 473|Homo sapiens
calcium/calmodulin-dependent protein kinase IV protein.
Length = 473
Score = 106 bits (255), Expect = 7e-23
Identities = 65/183 (35%), Positives = 105/183 (57%)
Frame = +3
Query: 171 FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQH 350
F + +G GA ++VY+ K+K + A+KV+ KK + K +I+ EI +L L+ H
Sbjct: 46 FEVESELGRGATSIVYRC-KQKGTQKPYALKVL-KKTVDK--KIVRTEIGVLLRLS---H 98
Query: 351 KNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAK 530
N++ + + ++P + +V+E GG+L D + SE + Q+ EA++ +H
Sbjct: 99 PNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHEN 158
Query: 531 GIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYMAP 710
GIVHRDLKP+N+L TP P D LKIADFG ++ +E + T+CG+P Y AP
Sbjct: 159 GIVHRDLKPENLLYA-------TPAP-DAPLKIADFGLSKIVEHQVLMKTVCGTPGYCAP 210
Query: 711 EVI 719
E++
Sbjct: 211 EIL 213
>BC016695-1|AAH16695.2| 503|Homo sapiens CAMK4 protein protein.
Length = 503
Score = 106 bits (255), Expect = 7e-23
Identities = 65/183 (35%), Positives = 105/183 (57%)
Frame = +3
Query: 171 FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQH 350
F + +G GA ++VY+ K+K + A+KV+ KK + K +I+ EI +L L+ H
Sbjct: 76 FEVESELGRGATSIVYRC-KQKGTQKPYALKVL-KKTVDK--KIVRTEIGVLLRLS---H 128
Query: 351 KNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAK 530
N++ + + ++P + +V+E GG+L D + SE + Q+ EA++ +H
Sbjct: 129 PNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHEN 188
Query: 531 GIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYMAP 710
GIVHRDLKP+N+L TP P D LKIADFG ++ +E + T+CG+P Y AP
Sbjct: 189 GIVHRDLKPENLLYA-------TPAP-DAPLKIADFGLSKIVEHQVLMKTVCGTPGYCAP 240
Query: 711 EVI 719
E++
Sbjct: 241 EIL 243
>BC012622-1|AAH12622.1| 207|Homo sapiens PRKAA1 protein protein.
Length = 207
Score = 106 bits (255), Expect = 7e-23
Identities = 60/190 (31%), Positives = 103/190 (54%)
Frame = +3
Query: 150 IQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILR 329
+++G Y D +G G F V G K + VAVK++ ++ I ++ +++ K + ++
Sbjct: 13 VKIGHYILG--DTLGVGTFGKVKVG-KHELTGHKVAVKILNRQKI-RSLDVVGKIRREIQ 68
Query: 330 ELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEA 509
L +H +++ ++ + +P+ +++VMEY +GG+L DY+ N L E + Q+
Sbjct: 69 NLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSG 128
Query: 510 MSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCG 689
+ H +VHRDLKP+N+LL + + KIADFG + + +G T CG
Sbjct: 129 VDYCHRHMVVHRDLKPENVLL-----------DAHMNAKIADFGLSNMMSDGEFLRTSCG 177
Query: 690 SPMYMAPEVI 719
SP Y APEVI
Sbjct: 178 SPNYAAPEVI 187
>AB022341-1|BAA81746.1| 454|Homo sapiens ZIP kinase protein.
Length = 454
Score = 106 bits (255), Expect = 7e-23
Identities = 60/182 (32%), Positives = 102/182 (56%), Gaps = 5/182 (2%)
Frame = +3
Query: 189 IGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-----EILVKEIKILRELTALQHK 353
+G G FA+V K R+ K + A K + K+ + + E + +E+ ILRE+ +H
Sbjct: 19 LGSGQFAIVRKCRQ-KGTGKEYAAKFIKKRRLSSSRRGVSREEIEREVNILREI---RHP 74
Query: 354 NLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKG 533
N++ +HD ++ V +++E +GG+L D+L L+E FL Q+ + + +H+K
Sbjct: 75 NIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLHSKR 134
Query: 534 IVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYMAPE 713
I H DLKP+NI+L L P+P +K+ DFG A +E GN + G+P ++APE
Sbjct: 135 IAHFDLKPENIML----LDKNVPNP---RIKLIDFGIAHKIEAGNEFKNIFGTPEFVAPE 187
Query: 714 VI 719
++
Sbjct: 188 IV 189
>AB022017-1|BAA36547.1| 550|Homo sapiens AMP-activated protein
kinase alpha-1 protein.
Length = 550
Score = 106 bits (255), Expect = 7e-23
Identities = 60/190 (31%), Positives = 103/190 (54%)
Frame = +3
Query: 150 IQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILR 329
+++G Y D +G G F V G K + VAVK++ ++ I ++ +++ K + ++
Sbjct: 13 VKIGHYILG--DTLGVGTFGKVKVG-KHELTGHKVAVKILNRQKI-RSLDVVGKIRREIQ 68
Query: 330 ELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEA 509
L +H +++ ++ + +P+ +++VMEY +GG+L DY+ N L E + Q+
Sbjct: 69 NLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSG 128
Query: 510 MSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCG 689
+ H +VHRDLKP+N+LL + + KIADFG + + +G T CG
Sbjct: 129 VDYCHRHMVVHRDLKPENVLL-----------DAHMNAKIADFGLSNMMSDGEFLRTSCG 177
Query: 690 SPMYMAPEVI 719
SP Y APEVI
Sbjct: 178 SPNYAAPEVI 187
>AB007144-1|BAA24955.1| 454|Homo sapiens ZIP-kinase protein.
Length = 454
Score = 106 bits (255), Expect = 7e-23
Identities = 60/182 (32%), Positives = 102/182 (56%), Gaps = 5/182 (2%)
Frame = +3
Query: 189 IGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-----EILVKEIKILRELTALQHK 353
+G G FA+V K R+ K + A K + K+ + + E + +E+ ILRE+ +H
Sbjct: 19 LGSGQFAIVRKCRQ-KGTGKEYAAKFIKKRRLSSSRRGVSREEIEREVNILREI---RHP 74
Query: 354 NLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKG 533
N++ +HD ++ V +++E +GG+L D+L L+E FL Q+ + + +H+K
Sbjct: 75 NIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLHSKR 134
Query: 534 IVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYMAPE 713
I H DLKP+NI+L L P+P +K+ DFG A +E GN + G+P ++APE
Sbjct: 135 IAHFDLKPENIML----LDKNVPNP---RIKLIDFGIAHKIEAGNEFKNIFGTPEFVAPE 187
Query: 714 VI 719
++
Sbjct: 188 IV 189
>U64205-1|AAC15093.1| 729|Homo sapiens Cdc25C associated protein
kinase C-TAK1 protein.
Length = 729
Score = 106 bits (254), Expect = 9e-23
Identities = 64/188 (34%), Positives = 101/188 (53%), Gaps = 1/188 (0%)
Frame = +3
Query: 156 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKILRE 332
+G+Y K IG G FA V R + VA+K++ K + S + L +E++I++
Sbjct: 53 IGNYRLLKT--IGKGNFAKVKLARHILT-GREVAIKIIDKTQLNPTSLQKLFREVRIMK- 108
Query: 333 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 512
L H N+V + + +++ +Y++MEY +GG++ DYL + + E + Q+ A+
Sbjct: 109 --ILNHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAV 166
Query: 513 SAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGS 692
H K IVHRDLK +N+LL +D+ +KIADFGF+ G T CGS
Sbjct: 167 QYCHQKRIVHRDLKAENLLL-----------DADMNIKIADFGFSNEFTVGGKLDTFCGS 215
Query: 693 PMYMAPEV 716
P Y APE+
Sbjct: 216 PPYAAPEL 223
>BC038504-1|AAH38504.1| 783|Homo sapiens SNF1-like kinase protein.
Length = 783
Score = 106 bits (254), Expect = 9e-23
Identities = 62/190 (32%), Positives = 105/190 (55%), Gaps = 1/190 (0%)
Frame = +3
Query: 150 IQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKIL 326
++VG Y+ + +G G FA+V R R +Q VA+K++ K + ++ E + +E++++
Sbjct: 22 LRVGFYDIERT--LGKGNFAVVKLARHRVTKTQ-VAIKIIDKTRLDSSNLEKIYREVQLM 78
Query: 327 RELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAE 506
+ L H +++ ++ M++ +Y+V E+ G++ DYL +N LSE + Q+
Sbjct: 79 K---LLNHPHIIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILS 135
Query: 507 AMSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLC 686
A+ H IVHRDLK +N+LL ++ +K+ADFGF F + G T C
Sbjct: 136 AVEYCHDHHIVHRDLKTENLLL-----------DGNMDIKLADFGFGNFYKSGEPLSTWC 184
Query: 687 GSPMYMAPEV 716
GSP Y APEV
Sbjct: 185 GSPPYAAPEV 194
>BC024773-1|AAH24773.1| 729|Homo sapiens MAP/microtubule
affinity-regulating kinase 3 protein.
Length = 729
Score = 106 bits (254), Expect = 9e-23
Identities = 64/188 (34%), Positives = 101/188 (53%), Gaps = 1/188 (0%)
Frame = +3
Query: 156 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKILRE 332
+G+Y K IG G FA V R + VA+K++ K + S + L +E++I++
Sbjct: 53 IGNYRLLKT--IGKGNFAKVKLARHILT-GREVAIKIIDKTQLNPTSLQKLFREVRIMK- 108
Query: 333 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 512
L H N+V + + +++ +Y++MEY +GG++ DYL + + E + Q+ A+
Sbjct: 109 --ILNHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAV 166
Query: 513 SAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGS 692
H K IVHRDLK +N+LL +D+ +KIADFGF+ G T CGS
Sbjct: 167 QYCHQKRIVHRDLKAENLLL-----------DADMNIKIADFGFSNEFTVGGKLDTFCGS 215
Query: 693 PMYMAPEV 716
P Y APE+
Sbjct: 216 PPYAAPEL 223
>AK131076-1|BAC85126.1| 764|Homo sapiens FLJ00263 protein protein.
Length = 764
Score = 106 bits (254), Expect = 9e-23
Identities = 62/190 (32%), Positives = 105/190 (55%), Gaps = 1/190 (0%)
Frame = +3
Query: 150 IQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKIL 326
++VG Y+ + +G G FA+V R R +Q VA+K++ K + ++ E + +E++++
Sbjct: 3 LRVGFYDIERT--LGKGNFAVVKLARHRVTKTQ-VAIKIIDKTRLDSSNLEKIYREVQLM 59
Query: 327 RELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAE 506
+ L H +++ ++ M++ +Y+V E+ G++ DYL +N LSE + Q+
Sbjct: 60 K---LLNHPHIIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILS 116
Query: 507 AMSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLC 686
A+ H IVHRDLK +N+LL ++ +K+ADFGF F + G T C
Sbjct: 117 AVEYCHDHHIVHRDLKTENLLL-----------DGNMDIKLADFGFGNFYKSGEPLSTWC 165
Query: 687 GSPMYMAPEV 716
GSP Y APEV
Sbjct: 166 GSPPYAAPEV 175
>AF387637-1|AAK82367.1| 744|Homo sapiens Ser/Thr protein kinase
PAR-1A protein.
Length = 744
Score = 106 bits (254), Expect = 9e-23
Identities = 64/188 (34%), Positives = 101/188 (53%), Gaps = 1/188 (0%)
Frame = +3
Query: 156 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKILRE 332
+G+Y K IG G FA V R + VA+K++ K + S + L +E++I++
Sbjct: 53 IGNYRLLKT--IGKGNFAKVKLARHILT-GREVAIKIIDKTQLNPTSLQKLFREVRIMK- 108
Query: 333 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 512
L H N+V + + +++ +Y++MEY +GG++ DYL + + E + Q+ A+
Sbjct: 109 --ILNHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAV 166
Query: 513 SAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGS 692
H K IVHRDLK +N+LL +D+ +KIADFGF+ G T CGS
Sbjct: 167 QYCHQKRIVHRDLKAENLLL-----------DADMNIKIADFGFSNEFTVGGKLDTFCGS 215
Query: 693 PMYMAPEV 716
P Y APE+
Sbjct: 216 PPYAAPEL 223
>AB047786-1|BAD74070.1| 783|Homo sapiens serine/threonine protein
kinase protein.
Length = 783
Score = 106 bits (254), Expect = 9e-23
Identities = 62/190 (32%), Positives = 105/190 (55%), Gaps = 1/190 (0%)
Frame = +3
Query: 150 IQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKIL 326
++VG Y+ + +G G FA+V R R +Q VA+K++ K + ++ E + +E++++
Sbjct: 22 LRVGFYDIERT--LGKGNFAVVKLARHRVTKTQ-VAIKIIDKTRLDSSNLEKIYREVQLM 78
Query: 327 RELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAE 506
+ L H +++ ++ M++ +Y+V E+ G++ DYL +N LSE + Q+
Sbjct: 79 K---LLNHPHIIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILS 135
Query: 507 AMSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLC 686
A+ H IVHRDLK +N+LL ++ +K+ADFGF F + G T C
Sbjct: 136 AVEYCHDHHIVHRDLKTENLLL-----------DGNMDIKLADFGFGNFYKSGEPLSTWC 184
Query: 687 GSPMYMAPEV 716
GSP Y APEV
Sbjct: 185 GSPPYAAPEV 194
>M80359-1|AAA59991.1| 713|Homo sapiens protein p78 protein.
Length = 713
Score = 105 bits (251), Expect = 2e-22
Identities = 64/188 (34%), Positives = 100/188 (53%), Gaps = 1/188 (0%)
Frame = +3
Query: 156 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKILRE 332
+G+Y K IG G FA V R + VA+K++ K + S + L +E++I++
Sbjct: 53 IGNYRLLKT--IGKGNFAKVKLARHILT-GREVAIKIIDKTQLNPTSLQKLFREVRIMK- 108
Query: 333 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 512
L H N+V + + +++ +Y++MEY +GG + DYL + + E + Q+ A+
Sbjct: 109 --ILNHPNIVKLFEVIETQKTLYLIMEYASGGKVFDYLVAHGRMKEKEARSKFRQIVSAV 166
Query: 513 SAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGS 692
H K IVHRDLK +N+LL +D+ +KIADFGF+ G T CGS
Sbjct: 167 QYCHQKRIVHRDLKAENLLL-----------DADMNIKIADFGFSNEFTVGGKLDTFCGS 215
Query: 693 PMYMAPEV 716
P Y APE+
Sbjct: 216 PPYAAPEL 223
>AF465413-1|AAL69982.1| 753|Homo sapiens MAP/microtubule
affinity-regulating kinase 3 long isoform protein.
Length = 753
Score = 105 bits (251), Expect = 2e-22
Identities = 64/188 (34%), Positives = 100/188 (53%), Gaps = 1/188 (0%)
Frame = +3
Query: 156 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKILRE 332
+G+Y K IG G FA V R + VA+K++ K + S + L +E++I++
Sbjct: 53 IGNYRLLKT--IGKGNFAKVKLARHILT-GREVAIKIIDKTQLNPTSLQKLFREVRIMK- 108
Query: 333 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 512
L H N+V + + +++ +Y++MEY +GG + DYL + + E + Q+ A+
Sbjct: 109 --ILNHPNIVKLFEVIETEKTLYLIMEYASGGKVFDYLVAHGRMKEKEARSKFRQIVSAV 166
Query: 513 SAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGS 692
H K IVHRDLK +N+LL +D+ +KIADFGF+ G T CGS
Sbjct: 167 QYCHQKRIVHRDLKAENLLL-----------DADMNIKIADFGFSNEFTVGGKLDTFCGS 215
Query: 693 PMYMAPEV 716
P Y APE+
Sbjct: 216 PPYAAPEL 223
>BC015472-1|AAH15472.1| 363|Homo sapiens PRKD2 protein protein.
Length = 363
Score = 104 bits (250), Expect = 3e-22
Identities = 64/189 (33%), Positives = 105/189 (55%), Gaps = 2/189 (1%)
Frame = +3
Query: 165 YEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVK-EIKILRELTA 341
Y+ +++G G F +VY G+ RK + VAVKV+ K E ++ E+ IL+ +
Sbjct: 34 YQIFPDEVLGSGQFGVVYGGKHRKT-GRDVAVKVIDKLRFPTKQESQLRNEVAILQ---S 89
Query: 342 LQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNR-LLSETTIQLFLAQLAEAMSA 518
L+H +V + ++P V+VVME +G L L + + L E + + Q+ A+
Sbjct: 90 LRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGRLPERLTKFLITQILVALRH 149
Query: 519 IHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPM 698
+H K IVH DLKP+N+LL + P P +K+ DFGFAR + E + ++ G+P
Sbjct: 150 LHFKNIVHCDLKPENVLLASA-----DPFPQ---VKLCDFGFARIIGEKSFRRSVVGTPA 201
Query: 699 YMAPEVIMS 725
Y+APEV+++
Sbjct: 202 YLAPEVLLN 210
>AK075266-1|BAC11508.1| 721|Homo sapiens protein ( Homo sapiens
cDNA FLJ90785 fis, clone THYRO1001457, moderately
similar to H.sapiens mRNA for protein kinase C mu. ).
Length = 721
Score = 104 bits (250), Expect = 3e-22
Identities = 64/189 (33%), Positives = 105/189 (55%), Gaps = 2/189 (1%)
Frame = +3
Query: 165 YEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVK-EIKILRELTA 341
Y+ +++G G F +VY G+ RK + VAVKV+ K E ++ E+ IL+ +
Sbjct: 392 YQIFPDEVLGSGQFGVVYGGKHRKT-GRDVAVKVIDKLRFPTKQESQLRNEVAILQ---S 447
Query: 342 LQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNR-LLSETTIQLFLAQLAEAMSA 518
L+H +V + ++P V+VVME +G L L + + L E + + Q+ A+
Sbjct: 448 LRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGRLPERLTKFLITQILVALRH 507
Query: 519 IHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPM 698
+H K IVH DLKP+N+LL + P P +K+ DFGFAR + E + ++ G+P
Sbjct: 508 LHFKNIVHCDLKPENVLLASA-----DPFPQ---VKLCDFGFARIIGEKSFRRSVVGTPA 559
Query: 699 YMAPEVIMS 725
Y+APEV+++
Sbjct: 560 YLAPEVLLN 568
>AK074673-1|BAC11127.1| 721|Homo sapiens protein ( Homo sapiens
cDNA FLJ90192 fis, clone MAMMA1001150, moderately
similar to PROTEIN KINASE C, MU TYPE (EC 2.7.1.-). ).
Length = 721
Score = 104 bits (250), Expect = 3e-22
Identities = 64/189 (33%), Positives = 105/189 (55%), Gaps = 2/189 (1%)
Frame = +3
Query: 165 YEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVK-EIKILRELTA 341
Y+ +++G G F +VY G+ RK + VAVKV+ K E ++ E+ IL+ +
Sbjct: 392 YQIFPDEVLGSGQFGVVYGGKHRKT-GRDVAVKVIDKLRFPTKQESQLRNEVAILQ---S 447
Query: 342 LQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNR-LLSETTIQLFLAQLAEAMSA 518
L+H +V + ++P V+VVME +G L L + + L E + + Q+ A+
Sbjct: 448 LRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGRLPERLTKFLITQILVALRH 507
Query: 519 IHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPM 698
+H K IVH DLKP+N+LL + P P +K+ DFGFAR + E + ++ G+P
Sbjct: 508 LHFKNIVHCDLKPENVLLASA-----DPFPQ---VKLCDFGFARIIGEKSFRRSVVGTPA 559
Query: 699 YMAPEVIMS 725
Y+APEV+++
Sbjct: 560 YLAPEVLLN 568
>AF309082-1|AAK01149.1| 878|Homo sapiens protein kinase D2 protein.
Length = 878
Score = 104 bits (250), Expect = 3e-22
Identities = 64/189 (33%), Positives = 105/189 (55%), Gaps = 2/189 (1%)
Frame = +3
Query: 165 YEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVK-EIKILRELTA 341
Y+ +++G G F +VY G+ RK + VAVKV+ K E ++ E+ IL+ +
Sbjct: 549 YQIFPDEVLGSGQFGVVYGGKHRKT-GRDVAVKVIDKLRFPTKQESQLRNEVAILQ---S 604
Query: 342 LQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNR-LLSETTIQLFLAQLAEAMSA 518
L+H +V + ++P V+VVME +G L L + + L E + + Q+ A+
Sbjct: 605 LRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGRLPERLTKFLITQILVALRH 664
Query: 519 IHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPM 698
+H K IVH DLKP+N+LL + P P +K+ DFGFAR + E + ++ G+P
Sbjct: 665 LHFKNIVHCDLKPENVLLASA-----DPFPQ---VKLCDFGFARIIGEKSFRRSVVGTPA 716
Query: 699 YMAPEVIMS 725
Y+APEV+++
Sbjct: 717 YLAPEVLLN 725
>BC031231-1|AAH31231.1| 514|Homo sapiens serine/threonine kinase 33
protein.
Length = 514
Score = 104 bits (249), Expect = 4e-22
Identities = 56/185 (30%), Positives = 105/185 (56%), Gaps = 2/185 (1%)
Frame = +3
Query: 171 FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQH 350
+T I+G G+F +V + ++ ++ KV +K A ++L +E+ IL+ +++H
Sbjct: 116 YTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILK---SVKH 172
Query: 351 KNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAK 530
++++ + ++P +Y+VME C G+L + L SE + + LA A++ +H
Sbjct: 173 EHIIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNN 232
Query: 531 GIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAV--TLCGSPMYM 704
IVHRDLK +NI++ S++ + ++ +K+ DFG A + + A+ CG+P+YM
Sbjct: 233 DIVHRDLKLENIMVKSSLIDDN--NEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYM 290
Query: 705 APEVI 719
APEVI
Sbjct: 291 APEVI 295
>AK093251-1|BAC04109.1| 514|Homo sapiens protein ( Homo sapiens
cDNA FLJ35932 fis, clone TESTI2011286, weakly similar to
MYOSIN LIGHT CHAIN KINASE (EC 2.7.1.117). ).
Length = 514
Score = 104 bits (249), Expect = 4e-22
Identities = 56/185 (30%), Positives = 105/185 (56%), Gaps = 2/185 (1%)
Frame = +3
Query: 171 FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQH 350
+T I+G G+F +V + ++ ++ KV +K A ++L +E+ IL+ +++H
Sbjct: 116 YTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILK---SVKH 172
Query: 351 KNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAK 530
++++ + ++P +Y+VME C G+L + L SE + + LA A++ +H
Sbjct: 173 EHIIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNN 232
Query: 531 GIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAV--TLCGSPMYM 704
IVHRDLK +NI++ S++ + ++ +K+ DFG A + + A+ CG+P+YM
Sbjct: 233 DIVHRDLKLENIMVKSSLIDDN--NEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYM 290
Query: 705 APEVI 719
APEVI
Sbjct: 291 APEVI 295
>AJ303380-1|CAC29064.1| 514|Homo sapiens serine/threonine kinase 33
protein.
Length = 514
Score = 104 bits (249), Expect = 4e-22
Identities = 56/185 (30%), Positives = 105/185 (56%), Gaps = 2/185 (1%)
Frame = +3
Query: 171 FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQH 350
+T I+G G+F +V + ++ ++ KV +K A ++L +E+ IL+ +++H
Sbjct: 116 YTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILK---SVKH 172
Query: 351 KNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAK 530
++++ + ++P +Y+VME C G+L + L SE + + LA A++ +H
Sbjct: 173 EHIIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNN 232
Query: 531 GIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAV--TLCGSPMYM 704
IVHRDLK +NI++ S++ + ++ +K+ DFG A + + A+ CG+P+YM
Sbjct: 233 DIVHRDLKLENIMVKSSLIDDN--NEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYM 290
Query: 705 APEVI 719
APEVI
Sbjct: 291 APEVI 295
>U22456-1|AAA64850.1| 174|Homo sapiens AMP-activated protein kinase
homolog protein.
Length = 174
Score = 103 bits (248), Expect = 5e-22
Identities = 57/174 (32%), Positives = 96/174 (55%)
Frame = +3
Query: 198 GAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQHKNLVAMHDC 377
GAF V G K + VAVK++ ++ I ++ +++ K + ++ L +H +++ ++
Sbjct: 1 GAFGKVKVG-KHELTGHKVAVKILNRQKI-RSLDVVGKIRREIQNLKLFRHPHIIKLYQV 58
Query: 378 MDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIVHRDLKP 557
+ +P+ +++VMEY +GG+L DY+ N L E + Q+ + H +VHRDLKP
Sbjct: 59 ISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKP 118
Query: 558 QNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYMAPEVI 719
+N+LL + + KIADFG + + +G T CGSP Y APEVI
Sbjct: 119 ENVLL-----------DAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVI 161
>AB011109-1|BAA25463.2| 698|Homo sapiens KIAA0537 protein protein.
Length = 698
Score = 103 bits (248), Expect = 5e-22
Identities = 55/187 (29%), Positives = 104/187 (55%), Gaps = 2/187 (1%)
Frame = +3
Query: 165 YEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI--LVKEIKILRELT 338
+ + Q+ +G G + V + +R + + VA+K + K I+ ++ + +EI+I+ +
Sbjct: 90 HRYELQETLGKGTYGKVKRATERFS-GRVVAIKSIRKDKIKDEQDMVHIRREIEIM---S 145
Query: 339 ALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSA 518
+L H +++++++ ++ + ++MEY + G+L DY+ R LSE + F Q+ A+
Sbjct: 146 SLNHPHIISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHY 205
Query: 519 IHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPM 698
H G+VHRDLK +NILL + +KIADFG + ++ T CGSP+
Sbjct: 206 CHKNGVVHRDLKLENILL-----------DDNCNIKIADFGLSNLYQKDKFLQTFCGSPL 254
Query: 699 YMAPEVI 719
Y +PE++
Sbjct: 255 YASPEIV 261
>AC007390-1|AAY14817.1| 890|Homo sapiens unknown protein.
Length = 890
Score = 103 bits (247), Expect = 7e-22
Identities = 64/189 (33%), Positives = 102/189 (53%), Gaps = 2/189 (1%)
Frame = +3
Query: 165 YEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVK-EIKILRELTA 341
Y+ +++G G F +VY G+ RK + VA+KV+ K E ++ E+ IL+ L
Sbjct: 574 YQIFADEVLGSGQFGIVYGGKHRKT-GRDVAIKVIDKMRFPTKQESQLRNEVAILQNL-- 630
Query: 342 LQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRL-LSETTIQLFLAQLAEAMSA 518
H +V + ++P V+VVME +G L L + + L E + + Q+ A+
Sbjct: 631 -HHPGIVNLECMFETPERVFVVMEKLHGDMLEMILSSEKSRLPERITKFMVTQILVALRN 689
Query: 519 IHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPM 698
+H K IVH DLKP+N+LL + P P +K+ DFGFAR + E + ++ G+P
Sbjct: 690 LHFKNIVHCDLKPENVLLASA-----EPFPQ---VKLCDFGFARIIGEKSFRRSVVGTPA 741
Query: 699 YMAPEVIMS 725
Y+APEV+ S
Sbjct: 742 YLAPEVLRS 750
>AB015982-1|BAA36514.1| 890|Homo sapiens serine/threonine kinase
protein.
Length = 890
Score = 103 bits (247), Expect = 7e-22
Identities = 64/189 (33%), Positives = 102/189 (53%), Gaps = 2/189 (1%)
Frame = +3
Query: 165 YEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVK-EIKILRELTA 341
Y+ +++G G F +VY G+ RK + VA+KV+ K E ++ E+ IL+ L
Sbjct: 574 YQIFADEVLGSGQFGIVYGGKHRKT-GRDVAIKVIDKMRFPTKQESQLRNEVAILQNL-- 630
Query: 342 LQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRL-LSETTIQLFLAQLAEAMSA 518
H +V + ++P V+VVME +G L L + + L E + + Q+ A+
Sbjct: 631 -HHPGIVNLECMFETPERVFVVMEKLHGDMLEMILSSEKSRLPERITKFMVTQILVALRN 689
Query: 519 IHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPM 698
+H K IVH DLKP+N+LL + P P +K+ DFGFAR + E + ++ G+P
Sbjct: 690 LHFKNIVHCDLKPENVLLASA-----EPFPQ---VKLCDFGFARIIGEKSFRRSVVGTPA 741
Query: 699 YMAPEVIMS 725
Y+APEV+ S
Sbjct: 742 YLAPEVLRS 750
>AY120867-1|AAM55491.1| 752|Homo sapiens MAP/microtubule
affinity-regulating kinase-like 1 protein.
Length = 752
Score = 103 bits (246), Expect = 9e-22
Identities = 63/188 (33%), Positives = 102/188 (54%), Gaps = 1/188 (0%)
Frame = +3
Query: 156 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKILRE 332
VG+Y + IG G FA V R + VA+K++ K + +S + L +E++I++
Sbjct: 56 VGNYRLLRT--IGKGNFAKVKLARHILT-GREVAIKIIDKTQLNPSSLQKLFREVRIMK- 111
Query: 333 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 512
L H N+V + + +++ +Y+VMEY + G++ DYL ++ + E + Q+ A+
Sbjct: 112 --GLNHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAV 169
Query: 513 SAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGS 692
H K IVHRDLK +N+LL ++ +KIADFGF+ G+ T CGS
Sbjct: 170 HYCHQKNIVHRDLKAENLLL-----------DAEANIKIADFGFSNEFTLGSKLDTFCGS 218
Query: 693 PMYMAPEV 716
P Y APE+
Sbjct: 219 PPYAAPEL 226
>AY057448-1|AAL23683.1| 752|Homo sapiens MARK4 serine/threonine
protein kinase protein.
Length = 752
Score = 103 bits (246), Expect = 9e-22
Identities = 63/188 (33%), Positives = 102/188 (54%), Gaps = 1/188 (0%)
Frame = +3
Query: 156 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKILRE 332
VG+Y + IG G FA V R + VA+K++ K + +S + L +E++I++
Sbjct: 56 VGNYRLLRT--IGKGNFAKVKLARHILT-GREVAIKIIDKTQLNPSSLQKLFREVRIMK- 111
Query: 333 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 512
L H N+V + + +++ +Y+VMEY + G++ DYL ++ + E + Q+ A+
Sbjct: 112 --GLNHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAV 169
Query: 513 SAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGS 692
H K IVHRDLK +N+LL ++ +KIADFGF+ G+ T CGS
Sbjct: 170 HYCHQKNIVHRDLKAENLLL-----------DAEANIKIADFGFSNEFTLGSKLDTFCGS 218
Query: 693 PMYMAPEV 716
P Y APE+
Sbjct: 219 PPYAAPEL 226
>AK075272-1|BAC11510.1| 752|Homo sapiens protein ( Homo sapiens
cDNA FLJ90791 fis, clone THYRO1001593, moderately
similar to PUTATIVE SERINE/THREONINE-PROTEIN KINASE P78
(EC 2.7.1.-). ).
Length = 752
Score = 103 bits (246), Expect = 9e-22
Identities = 63/188 (33%), Positives = 102/188 (54%), Gaps = 1/188 (0%)
Frame = +3
Query: 156 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKILRE 332
VG+Y + IG G FA V R + VA+K++ K + +S + L +E++I++
Sbjct: 56 VGNYRLLRT--IGKGNFAKVKLARHILT-GREVAIKIIDKTQLNPSSLQKLFREVRIMK- 111
Query: 333 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 512
L H N+V + + +++ +Y+VMEY + G++ DYL ++ + E + Q+ A+
Sbjct: 112 --GLNHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAV 169
Query: 513 SAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGS 692
H K IVHRDLK +N+LL ++ +KIADFGF+ G+ T CGS
Sbjct: 170 HYCHQKNIVHRDLKAENLLL-----------DAEANIKIADFGFSNEFTLGSKLDTFCGS 218
Query: 693 PMYMAPEV 716
P Y APE+
Sbjct: 219 PPYAAPEL 226
>AB058763-1|BAB47489.1| 689|Homo sapiens KIAA1860 protein protein.
Length = 689
Score = 103 bits (246), Expect = 9e-22
Identities = 63/188 (33%), Positives = 102/188 (54%), Gaps = 1/188 (0%)
Frame = +3
Query: 156 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKILRE 332
VG+Y + IG G FA V R + VA+K++ K + +S + L +E++I++
Sbjct: 57 VGNYRLLRT--IGKGNFAKVKLARHILT-GREVAIKIIDKTQLNPSSLQKLFREVRIMK- 112
Query: 333 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 512
L H N+V + + +++ +Y+VMEY + G++ DYL ++ + E + Q+ A+
Sbjct: 113 --GLNHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAV 170
Query: 513 SAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGS 692
H K IVHRDLK +N+LL ++ +KIADFGF+ G+ T CGS
Sbjct: 171 HYCHQKNIVHRDLKAENLLL-----------DAEANIKIADFGFSNEFTLGSKLDTFCGS 219
Query: 693 PMYMAPEV 716
P Y APE+
Sbjct: 220 PPYAAPEL 227
>BC114506-1|AAI14507.1| 370|Homo sapiens death-associated protein
kinase 2 protein.
Length = 370
Score = 102 bits (244), Expect = 2e-21
Identities = 61/180 (33%), Positives = 101/180 (56%), Gaps = 3/180 (1%)
Frame = +3
Query: 189 IGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQ---HKNL 359
+G G FA+V K R+ K+ A K + KK +AS V +I RE++ L+ H N+
Sbjct: 29 LGSGQFAIVKKCRE-KSTGLEYAAKFI-KKRQSRASRRGVSREEIEREVSILRQVLHHNV 86
Query: 360 VAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIV 539
+ +HD ++ V +++E +GG+L D+L LSE F+ Q+ + ++ +H K I
Sbjct: 87 ITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDGVNYLHTKKIA 146
Query: 540 HRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYMAPEVI 719
H DLKP+NI+L +P PH +K+ DFG A +E+G + G+P ++APE++
Sbjct: 147 HFDLKPENIMLLDKNIP--IPH-----IKLIDFGLAHEIEDGVEFKNIFGTPEFVAPEIV 199
>AF052941-1|AAC35001.1| 370|Homo sapiens DAP-kinase related protein
1 protein.
Length = 370
Score = 102 bits (244), Expect = 2e-21
Identities = 61/180 (33%), Positives = 101/180 (56%), Gaps = 3/180 (1%)
Frame = +3
Query: 189 IGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQ---HKNL 359
+G G FA+V K R+ K+ A K + KK +AS V +I RE++ L+ H N+
Sbjct: 29 LGSGQFAIVKKCRE-KSTGLEYAAKFI-KKRQSRASRRGVSREEIEREVSILRQVLHHNV 86
Query: 360 VAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIV 539
+ +HD ++ V +++E +GG+L D+L LSE F+ Q+ + ++ +H K I
Sbjct: 87 ITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDGVNYLHTKKIA 146
Query: 540 HRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYMAPEVI 719
H DLKP+NI+L +P PH +K+ DFG A +E+G + G+P ++APE++
Sbjct: 147 HFDLKPENIMLLDKNIP--IPH-----IKLIDFGLAHEIEDGVEFKNIFGTPEFVAPEIV 199
>AB018001-1|BAA88063.1| 370|Homo sapiens Death-associated protein
kinase 2 protein.
Length = 370
Score = 102 bits (244), Expect = 2e-21
Identities = 61/180 (33%), Positives = 101/180 (56%), Gaps = 3/180 (1%)
Frame = +3
Query: 189 IGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQ---HKNL 359
+G G FA+V K R+ K+ A K + KK +AS V +I RE++ L+ H N+
Sbjct: 29 LGSGQFAIVKKCRE-KSTGLEYAAKFI-KKRQSRASRRGVSREEIEREVSILRQVLHHNV 86
Query: 360 VAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIV 539
+ +HD ++ V +++E +GG+L D+L LSE F+ Q+ + ++ +H K I
Sbjct: 87 ITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDGVNYLHTKKIA 146
Query: 540 HRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYMAPEVI 719
H DLKP+NI+L +P PH +K+ DFG A +E+G + G+P ++APE++
Sbjct: 147 HFDLKPENIMLLDKNIP--IPH-----IKLIDFGLAHEIEDGVEFKNIFGTPEFVAPEIV 199
>U06454-1|AAA64745.1| 552|Homo sapiens AMP-activated protein kinase
protein.
Length = 552
Score = 101 bits (243), Expect = 2e-21
Identities = 58/190 (30%), Positives = 101/190 (53%)
Frame = +3
Query: 150 IQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILR 329
+++G Y D +G G F V G + VAVK++ ++ I ++ +++ K + ++
Sbjct: 11 VKIGHYVLG--DTLGVGTFGKVKIGEHQLT-GHKVAVKILNRQKI-RSLDVVGKIKREIQ 66
Query: 330 ELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEA 509
L +H +++ ++ + +P ++VMEY +GG+L DY+ + + E + Q+ A
Sbjct: 67 NLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSA 126
Query: 510 MSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCG 689
+ H +VHRDLKP+N+LL + + KIADFG + + +G T CG
Sbjct: 127 VDYCHRHMVVHRDLKPENVLL-----------DAHMNAKIADFGLSNMMSDGEFLRTSCG 175
Query: 690 SPMYMAPEVI 719
SP Y APEVI
Sbjct: 176 SPNYTAPEVI 185
>EF056019-1|ABK30810.1| 552|Homo sapiens AMP-activated alpha 2
subunit protein.
Length = 552
Score = 101 bits (243), Expect = 2e-21
Identities = 58/190 (30%), Positives = 101/190 (53%)
Frame = +3
Query: 150 IQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILR 329
+++G Y D +G G F V G + VAVK++ ++ I ++ +++ K + ++
Sbjct: 11 VKIGHYVLG--DTLGVGTFGKVNIGEHQLT-GHKVAVKILNRQKI-RSLDVVGKIKREIQ 66
Query: 330 ELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEA 509
L +H +++ ++ + +P ++VMEY +GG+L DY+ + + E + Q+ A
Sbjct: 67 NLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSA 126
Query: 510 MSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCG 689
+ H +VHRDLKP+N+LL + + KIADFG + + +G T CG
Sbjct: 127 VDYCHRHMVVHRDLKPENVLL-----------DAHMNAKIADFGLSNMMSDGEFLRTSCG 175
Query: 690 SPMYMAPEVI 719
SP Y APEVI
Sbjct: 176 SPNYAAPEVI 185
>BC069823-1|AAH69823.1| 552|Homo sapiens AMP-activated protein
kinase alpha 2 catalytic subunit protein.
Length = 552
Score = 101 bits (243), Expect = 2e-21
Identities = 58/190 (30%), Positives = 101/190 (53%)
Frame = +3
Query: 150 IQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILR 329
+++G Y D +G G F V G + VAVK++ ++ I ++ +++ K + ++
Sbjct: 11 VKIGHYVLG--DTLGVGTFGKVKIGEHQLT-GHKVAVKILNRQKI-RSLDVVGKIKREIQ 66
Query: 330 ELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEA 509
L +H +++ ++ + +P ++VMEY +GG+L DY+ + + E + Q+ A
Sbjct: 67 NLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSA 126
Query: 510 MSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCG 689
+ H +VHRDLKP+N+LL + + KIADFG + + +G T CG
Sbjct: 127 VDYCHRHMVVHRDLKPENVLL-----------DAHMNAKIADFGLSNMMSDGEFLRTSCG 175
Query: 690 SPMYMAPEVI 719
SP Y APEVI
Sbjct: 176 SPNYAAPEVI 185
>BC069740-1|AAH69740.1| 552|Homo sapiens AMP-activated protein
kinase alpha 2 catalytic subunit protein.
Length = 552
Score = 101 bits (243), Expect = 2e-21
Identities = 58/190 (30%), Positives = 101/190 (53%)
Frame = +3
Query: 150 IQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILR 329
+++G Y D +G G F V G + VAVK++ ++ I ++ +++ K + ++
Sbjct: 11 VKIGHYVLG--DTLGVGTFGKVKIGEHQLT-GHKVAVKILNRQKI-RSLDVVGKIKREIQ 66
Query: 330 ELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEA 509
L +H +++ ++ + +P ++VMEY +GG+L DY+ + + E + Q+ A
Sbjct: 67 NLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSA 126
Query: 510 MSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCG 689
+ H +VHRDLKP+N+LL + + KIADFG + + +G T CG
Sbjct: 127 VDYCHRHMVVHRDLKPENVLL-----------DAHMNAKIADFGLSNMMSDGEFLRTSCG 175
Query: 690 SPMYMAPEVI 719
SP Y APEVI
Sbjct: 176 SPNYAAPEVI 185
>BC069680-1|AAH69680.1| 552|Homo sapiens protein kinase,
AMP-activated, alpha 2 catalytic subunit protein.
Length = 552
Score = 101 bits (243), Expect = 2e-21
Identities = 58/190 (30%), Positives = 101/190 (53%)
Frame = +3
Query: 150 IQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILR 329
+++G Y D +G G F V G + VAVK++ ++ I ++ +++ K + ++
Sbjct: 11 VKIGHYVLG--DTLGVGTFGKVKIGEHQLT-GHKVAVKILNRQKI-RSLDVVGKIKREIQ 66
Query: 330 ELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEA 509
L +H +++ ++ + +P ++VMEY +GG+L DY+ + + E + Q+ A
Sbjct: 67 NLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSA 126
Query: 510 MSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCG 689
+ H +VHRDLKP+N+LL + + KIADFG + + +G T CG
Sbjct: 127 VDYCHRHMVVHRDLKPENVLL-----------DAHMNAKIADFGLSNMMSDGEFLRTSCG 175
Query: 690 SPMYMAPEVI 719
SP Y APEVI
Sbjct: 176 SPNYAAPEVI 185
>BC036422-1|AAH36422.1| 436|Homo sapiens hypothetical protein
MGC42105 protein.
Length = 436
Score = 101 bits (243), Expect = 2e-21
Identities = 58/177 (32%), Positives = 97/177 (54%), Gaps = 1/177 (0%)
Frame = +3
Query: 189 IGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGI-QKASEILVKEIKILRELTALQHKNLVA 365
IG G F+ V G + VA+K++ K + QK +L +EI + +L H N++
Sbjct: 80 IGSGNFSQVKLGIHSLT-KEKVAIKILDKTKLDQKTQRLLSREISSMEKL---HHPNIIR 135
Query: 366 MHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIVHR 545
+++ +++ + +++VMEY GG+L + T LSE +L +Q+ A+ +H I+HR
Sbjct: 136 LYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQIVSAVKHMHENQIIHR 195
Query: 546 DLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYMAPEV 716
DLK +N+ T S+ +K+ DFGF+ ++G M T CGSP Y APE+
Sbjct: 196 DLKAENVFYT-----------SNTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPEL 241
>AP001751-1|BAA95536.1| 786|Homo sapiens SNF1LK protein.
Length = 786
Score = 101 bits (243), Expect = 2e-21
Identities = 63/191 (32%), Positives = 104/191 (54%), Gaps = 2/191 (1%)
Frame = +3
Query: 150 IQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKIL 326
++VG Y+ + +G G FA+V R R +Q VA+K++ K + ++ E + +E++++
Sbjct: 22 LRVGFYDIERT--LGKGNFAVVKLARHRVTKTQ-VAIKIIDKTRLDSSNLEKIYREVQLM 78
Query: 327 RELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAE 506
+ L H +++ ++ M++ +Y+V E+ G++ DYL +N LSE + Q+
Sbjct: 79 K---LLNHPHIIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILS 135
Query: 507 AMSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLK-IADFGFARFLEEGNMAVTL 683
A+ H IVHRDLK +N+LL ++ DI L DFGF F + G T
Sbjct: 136 AVEYCHDHHIVHRDLKTENLLLDGNM---------DIKLAGTEDFGFGNFYKSGEPLSTW 186
Query: 684 CGSPMYMAPEV 716
CGSP Y APEV
Sbjct: 187 CGSPPYAAPEV 197
>AL035705-2|CAC17574.2| 552|Homo sapiens protein kinase,
AMP-activated, alpha 2 catalytic subunit protein.
Length = 552
Score = 101 bits (243), Expect = 2e-21
Identities = 58/190 (30%), Positives = 101/190 (53%)
Frame = +3
Query: 150 IQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILR 329
+++G Y D +G G F V G + VAVK++ ++ I ++ +++ K + ++
Sbjct: 11 VKIGHYVLG--DTLGVGTFGKVKIGEHQLT-GHKVAVKILNRQKI-RSLDVVGKIKREIQ 66
Query: 330 ELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEA 509
L +H +++ ++ + +P ++VMEY +GG+L DY+ + + E + Q+ A
Sbjct: 67 NLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSA 126
Query: 510 MSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCG 689
+ H +VHRDLKP+N+LL + + KIADFG + + +G T CG
Sbjct: 127 VDYCHRHMVVHRDLKPENVLL-----------DAHMNAKIADFGLSNMMSDGEFLRTSCG 175
Query: 690 SPMYMAPEVI 719
SP Y APEVI
Sbjct: 176 SPNYAAPEVI 185
>BC032787-1|AAH32787.1| 476|Homo sapiens
calcium/calmodulin-dependent protein kinase IG protein.
Length = 476
Score = 101 bits (242), Expect = 3e-21
Identities = 60/183 (32%), Positives = 103/183 (56%)
Frame = +3
Query: 171 FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQH 350
F +++G GAF+ V+ ++R + A+K + K + S L EI +L+++ +H
Sbjct: 23 FIFMEVLGSGAFSEVFLVKQRLT-GKLFALKCIKKSPAFRDSS-LENEIAVLKKI---KH 77
Query: 351 KNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAK 530
+N+V + D +S + Y+VM+ +GG+L D + + +E L + Q+ A+ +H
Sbjct: 78 ENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLHEN 137
Query: 531 GIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYMAP 710
GIVHRDLKP+N+L TP + + I DFG ++ + G M+ T CG+P Y+AP
Sbjct: 138 GIVHRDLKPENLLYL-------TPEENS-KIMITDFGLSKMEQNGIMS-TACGTPGYVAP 188
Query: 711 EVI 719
EV+
Sbjct: 189 EVL 191
>AY212935-1|AAP29964.1| 460|Homo sapiens CLICK III protein.
Length = 460
Score = 101 bits (242), Expect = 3e-21
Identities = 60/183 (32%), Positives = 103/183 (56%)
Frame = +3
Query: 171 FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQH 350
F +++G GAF+ V+ ++R + A+K + K + S L EI +L+++ +H
Sbjct: 23 FIFMEVLGSGAFSEVFLVKQRLT-GKLFALKCIKKSPAFRDSS-LENEIAVLKKI---KH 77
Query: 351 KNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAK 530
+N+V + D +S + Y+VM+ +GG+L D + + +E L + Q+ A+ +H
Sbjct: 78 ENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLHEN 137
Query: 531 GIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYMAP 710
GIVHRDLKP+N+L TP + + I DFG ++ + G M+ T CG+P Y+AP
Sbjct: 138 GIVHRDLKPENLLYL-------TPEENS-KIMITDFGLSKMEQNGIMS-TACGTPGYVAP 188
Query: 711 EVI 719
EV+
Sbjct: 189 EVL 191
>AL049688-1|CAB41259.1| 481|Homo sapiens hypothetical protein
protein.
Length = 481
Score = 101 bits (242), Expect = 3e-21
Identities = 60/183 (32%), Positives = 103/183 (56%)
Frame = +3
Query: 171 FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQH 350
F +++G GAF+ V+ ++R + A+K + K + S L EI +L+++ +H
Sbjct: 28 FIFMEVLGSGAFSEVFLVKQRLT-GKLFALKCIKKSPAFRDSS-LENEIAVLKKI---KH 82
Query: 351 KNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAK 530
+N+V + D +S + Y+VM+ +GG+L D + + +E L + Q+ A+ +H
Sbjct: 83 ENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLHEN 142
Query: 531 GIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYMAP 710
GIVHRDLKP+N+L TP + + I DFG ++ + G M+ T CG+P Y+AP
Sbjct: 143 GIVHRDLKPENLLYL-------TPEENS-KIMITDFGLSKMEQNGIMS-TACGTPGYVAP 193
Query: 711 EVI 719
EV+
Sbjct: 194 EVL 196
>AL023754-3|CAI19991.1| 476|Homo sapiens
calcium/calmodulin-dependent protein kinase IG protein.
Length = 476
Score = 101 bits (242), Expect = 3e-21
Identities = 60/183 (32%), Positives = 103/183 (56%)
Frame = +3
Query: 171 FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQH 350
F +++G GAF+ V+ ++R + A+K + K + S L EI +L+++ +H
Sbjct: 23 FIFMEVLGSGAFSEVFLVKQRLT-GKLFALKCIKKSPAFRDSS-LENEIAVLKKI---KH 77
Query: 351 KNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAK 530
+N+V + D +S + Y+VM+ +GG+L D + + +E L + Q+ A+ +H
Sbjct: 78 ENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLHEN 137
Query: 531 GIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYMAP 710
GIVHRDLKP+N+L TP + + I DFG ++ + G M+ T CG+P Y+AP
Sbjct: 138 GIVHRDLKPENLLYL-------TPEENS-KIMITDFGLSKMEQNGIMS-TACGTPGYVAP 188
Query: 711 EVI 719
EV+
Sbjct: 189 EVL 191
>AF428261-1|AAL28100.1| 476|Homo sapiens
calcium/calmodulin-dependent protein kinase I gamma
protein.
Length = 476
Score = 101 bits (242), Expect = 3e-21
Identities = 60/183 (32%), Positives = 103/183 (56%)
Frame = +3
Query: 171 FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQH 350
F +++G GAF+ V+ ++R + A+K + K + S L EI +L+++ +H
Sbjct: 23 FIFMEVLGSGAFSEVFLVKQRLT-GKLFALKCIKKSPAFRDSS-LENEIAVLKKI---KH 77
Query: 351 KNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAK 530
+N+V + D +S + Y+VM+ +GG+L D + + +E L + Q+ A+ +H
Sbjct: 78 ENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLHEN 137
Query: 531 GIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYMAP 710
GIVHRDLKP+N+L TP + + I DFG ++ + G M+ T CG+P Y+AP
Sbjct: 138 GIVHRDLKPENLLYL-------TPEENS-KIMITDFGLSKMEQNGIMS-TACGTPGYVAP 188
Query: 711 EVI 719
EV+
Sbjct: 189 EVL 191
>X75756-1|CAA53384.1| 912|Homo sapiens protein kinase C mu protein.
Length = 912
Score = 101 bits (241), Expect = 3e-21
Identities = 62/187 (33%), Positives = 101/187 (54%), Gaps = 2/187 (1%)
Frame = +3
Query: 165 YEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVK-EIKILRELTA 341
Y+ +++G G F +VY G+ RK + VA+K++ K E ++ E+ IL+ L
Sbjct: 581 YQIFPDEVLGSGQFGIVYGGKHRKT-GRDVAIKIIDKLRFPTKQESQLRNEVAILQNL-- 637
Query: 342 LQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNR-LLSETTIQLFLAQLAEAMSA 518
H +V + ++P V+VVME +G L L + + L E + + Q+ A+
Sbjct: 638 -HHPGVVNLECMFETPERVFVVMEKLHGDMLEMILSSEKGRLPEHITKFLITQILVALRH 696
Query: 519 IHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPM 698
+H K IVH DLKP+N+LL + P P +K+ DFGFAR + E + ++ G+P
Sbjct: 697 LHFKNIVHCDLKPENVLLASA-----DPFPQ---VKLCDFGFARIIGEKSFRRSVVGTPA 748
Query: 699 YMAPEVI 719
Y+APEV+
Sbjct: 749 YLAPEVL 755
>DQ485452-1|ABE96833.1| 914|Homo sapiens protein kinase D1 protein.
Length = 914
Score = 101 bits (241), Expect = 3e-21
Identities = 62/187 (33%), Positives = 101/187 (54%), Gaps = 2/187 (1%)
Frame = +3
Query: 165 YEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVK-EIKILRELTA 341
Y+ +++G G F +VY G+ RK + VA+K++ K E ++ E+ IL+ L
Sbjct: 583 YQIFPDEVLGSGQFGIVYGGKHRKT-GRDVAIKIIDKLRFPTKQESQLRNEVAILQNL-- 639
Query: 342 LQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNR-LLSETTIQLFLAQLAEAMSA 518
H +V + ++P V+VVME +G L L + + L E + + Q+ A+
Sbjct: 640 -HHPGVVNLECMFETPERVFVVMEKLHGDMLEMILSSEKGRLPEHITKFLITQILVALRH 698
Query: 519 IHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPM 698
+H K IVH DLKP+N+LL + P P +K+ DFGFAR + E + ++ G+P
Sbjct: 699 LHFKNIVHCDLKPENVLLASA-----DPFPQ---VKLCDFGFARIIGEKSFRRSVVGTPA 750
Query: 699 YMAPEVI 719
Y+APEV+
Sbjct: 751 YLAPEVL 757
>AL390029-2|CAI15721.1| 740|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 740
Score = 100 bits (240), Expect = 5e-21
Identities = 59/177 (33%), Positives = 96/177 (54%)
Frame = +3
Query: 189 IGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQHKNLVAM 368
IG G FA+V K ++ ++ A+K++ K + ++ E+ ILR + +H N+V +
Sbjct: 396 IGDGNFAVV-KECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRV---KHPNIVLL 451
Query: 369 HDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIVHRD 548
+ MD P +Y+VME GGDL D + + +E L LA A+ +H+ IVHRD
Sbjct: 452 IEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRD 511
Query: 549 LKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYMAPEVI 719
+KP+N+L+ +LK+ DFG A ++ T+CG+P Y+APE+I
Sbjct: 512 IKPENLLVYEH-------QDGSKSLKLGDFGLATIVD--GPLYTVCGTPTYVAPEII 559
>AL390029-1|CAI15720.1| 729|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 729
Score = 100 bits (240), Expect = 5e-21
Identities = 59/177 (33%), Positives = 96/177 (54%)
Frame = +3
Query: 189 IGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQHKNLVAM 368
IG G FA+V K ++ ++ A+K++ K + ++ E+ ILR + +H N+V +
Sbjct: 396 IGDGNFAVV-KECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRV---KHPNIVLL 451
Query: 369 HDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIVHRD 548
+ MD P +Y+VME GGDL D + + +E L LA A+ +H+ IVHRD
Sbjct: 452 IEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRD 511
Query: 549 LKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYMAPEVI 719
+KP+N+L+ +LK+ DFG A ++ T+CG+P Y+APE+I
Sbjct: 512 IKPENLLVYEH-------QDGSKSLKLGDFGLATIVD--GPLYTVCGTPTYVAPEII 559
>AL160392-2|CAH70261.1| 740|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 740
Score = 100 bits (240), Expect = 5e-21
Identities = 59/177 (33%), Positives = 96/177 (54%)
Frame = +3
Query: 189 IGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQHKNLVAM 368
IG G FA+V K ++ ++ A+K++ K + ++ E+ ILR + +H N+V +
Sbjct: 396 IGDGNFAVV-KECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRV---KHPNIVLL 451
Query: 369 HDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIVHRD 548
+ MD P +Y+VME GGDL D + + +E L LA A+ +H+ IVHRD
Sbjct: 452 IEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRD 511
Query: 549 LKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYMAPEVI 719
+KP+N+L+ +LK+ DFG A ++ T+CG+P Y+APE+I
Sbjct: 512 IKPENLLVYEH-------QDGSKSLKLGDFGLATIVD--GPLYTVCGTPTYVAPEII 559
>AL160392-1|CAH70262.1| 729|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 729
Score = 100 bits (240), Expect = 5e-21
Identities = 59/177 (33%), Positives = 96/177 (54%)
Frame = +3
Query: 189 IGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQHKNLVAM 368
IG G FA+V K ++ ++ A+K++ K + ++ E+ ILR + +H N+V +
Sbjct: 396 IGDGNFAVV-KECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRV---KHPNIVLL 451
Query: 369 HDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIVHRD 548
+ MD P +Y+VME GGDL D + + +E L LA A+ +H+ IVHRD
Sbjct: 452 IEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRD 511
Query: 549 LKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYMAPEVI 719
+KP+N+L+ +LK+ DFG A ++ T+CG+P Y+APE+I
Sbjct: 512 IKPENLLVYEH-------QDGSKSLKLGDFGLATIVD--GPLYTVCGTPTYVAPEII 559
>AL157760-4|CAH70170.1| 433|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 433
Score = 100 bits (240), Expect = 5e-21
Identities = 59/177 (33%), Positives = 96/177 (54%)
Frame = +3
Query: 189 IGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQHKNLVAM 368
IG G FA+V K ++ ++ A+K++ K + ++ E+ ILR + +H N+V +
Sbjct: 89 IGDGNFAVV-KECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRV---KHPNIVLL 144
Query: 369 HDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIVHRD 548
+ MD P +Y+VME GGDL D + + +E L LA A+ +H+ IVHRD
Sbjct: 145 IEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRD 204
Query: 549 LKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYMAPEVI 719
+KP+N+L+ +LK+ DFG A ++ T+CG+P Y+APE+I
Sbjct: 205 IKPENLLVYEH-------QDGSKSLKLGDFGLATIVD--GPLYTVCGTPTYVAPEII 252
>AL157760-2|CAH70167.1| 740|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 740
Score = 100 bits (240), Expect = 5e-21
Identities = 59/177 (33%), Positives = 96/177 (54%)
Frame = +3
Query: 189 IGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQHKNLVAM 368
IG G FA+V K ++ ++ A+K++ K + ++ E+ ILR + +H N+V +
Sbjct: 396 IGDGNFAVV-KECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRV---KHPNIVLL 451
Query: 369 HDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIVHRD 548
+ MD P +Y+VME GGDL D + + +E L LA A+ +H+ IVHRD
Sbjct: 452 IEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRD 511
Query: 549 LKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYMAPEVI 719
+KP+N+L+ +LK+ DFG A ++ T+CG+P Y+APE+I
Sbjct: 512 IKPENLLVYEH-------QDGSKSLKLGDFGLATIVD--GPLYTVCGTPTYVAPEII 559
>AL157760-1|CAH70168.1| 729|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 729
Score = 100 bits (240), Expect = 5e-21
Identities = 59/177 (33%), Positives = 96/177 (54%)
Frame = +3
Query: 189 IGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQHKNLVAM 368
IG G FA+V K ++ ++ A+K++ K + ++ E+ ILR + +H N+V +
Sbjct: 396 IGDGNFAVV-KECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRV---KHPNIVLL 451
Query: 369 HDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIVHRD 548
+ MD P +Y+VME GGDL D + + +E L LA A+ +H+ IVHRD
Sbjct: 452 IEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRD 511
Query: 549 LKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYMAPEVI 719
+KP+N+L+ +LK+ DFG A ++ T+CG+P Y+APE+I
Sbjct: 512 IKPENLLVYEH-------QDGSKSLKLGDFGLATIVD--GPLYTVCGTPTYVAPEII 559
>AL157694-2|CAH70656.1| 740|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 740
Score = 100 bits (240), Expect = 5e-21
Identities = 59/177 (33%), Positives = 96/177 (54%)
Frame = +3
Query: 189 IGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQHKNLVAM 368
IG G FA+V K ++ ++ A+K++ K + ++ E+ ILR + +H N+V +
Sbjct: 396 IGDGNFAVV-KECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRV---KHPNIVLL 451
Query: 369 HDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIVHRD 548
+ MD P +Y+VME GGDL D + + +E L LA A+ +H+ IVHRD
Sbjct: 452 IEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRD 511
Query: 549 LKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYMAPEVI 719
+KP+N+L+ +LK+ DFG A ++ T+CG+P Y+APE+I
Sbjct: 512 IKPENLLVYEH-------QDGSKSLKLGDFGLATIVD--GPLYTVCGTPTYVAPEII 559
>AL157694-1|CAH70657.1| 729|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 729
Score = 100 bits (240), Expect = 5e-21
Identities = 59/177 (33%), Positives = 96/177 (54%)
Frame = +3
Query: 189 IGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQHKNLVAM 368
IG G FA+V K ++ ++ A+K++ K + ++ E+ ILR + +H N+V +
Sbjct: 396 IGDGNFAVV-KECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRV---KHPNIVLL 451
Query: 369 HDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIVHRD 548
+ MD P +Y+VME GGDL D + + +E L LA A+ +H+ IVHRD
Sbjct: 452 IEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRD 511
Query: 549 LKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYMAPEVI 719
+KP+N+L+ +LK+ DFG A ++ T+CG+P Y+APE+I
Sbjct: 512 IKPENLLVYEH-------QDGSKSLKLGDFGLATIVD--GPLYTVCGTPTYVAPEII 559
>AB002367-1|BAA20824.2| 794|Homo sapiens KIAA0369 protein.
Length = 794
Score = 100 bits (240), Expect = 5e-21
Identities = 59/177 (33%), Positives = 96/177 (54%)
Frame = +3
Query: 189 IGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQHKNLVAM 368
IG G FA+V K ++ ++ A+K++ K + ++ E+ ILR + +H N+V +
Sbjct: 461 IGDGNFAVV-KECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRV---KHPNIVLL 516
Query: 369 HDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIVHRD 548
+ MD P +Y+VME GGDL D + + +E L LA A+ +H+ IVHRD
Sbjct: 517 IEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRD 576
Query: 549 LKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYMAPEVI 719
+KP+N+L+ +LK+ DFG A ++ T+CG+P Y+APE+I
Sbjct: 577 IKPENLLVYEH-------QDGSKSLKLGDFGLATIVD--GPLYTVCGTPTYVAPEII 624
>X80590-1|CAA56681.1| 387|Homo sapiens phosphorylase kinase
protein.
Length = 387
Score = 100 bits (239), Expect = 6e-21
Identities = 63/194 (32%), Positives = 103/194 (53%), Gaps = 9/194 (4%)
Frame = +3
Query: 165 YE-FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKG--------IQKASEILVKEI 317
YE + ++I+G G ++V + K SQ AVKV+ G +++ E +KE+
Sbjct: 17 YENYEPKEILGRGVSSVVRRCI-HKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEV 75
Query: 318 KILRELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQ 497
ILR+++ H N++ + D ++ + ++V + G+L DYL LSE + +
Sbjct: 76 DILRKVSG--HPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRA 133
Query: 498 LAEAMSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAV 677
L E + +H IVHRDLKP+NILL ++ +K+ DFGF+ LE G
Sbjct: 134 LLEVICTLHKLNIVHRDLKPENILL-----------DDNMNIKLTDFGFSCQLEPGERLR 182
Query: 678 TLCGSPMYMAPEVI 719
+CG+P Y+APE+I
Sbjct: 183 EVCGTPSYLAPEII 196
>BC128510-1|AAI28511.1| 1203|Homo sapiens KIAA0999 protein protein.
Length = 1203
Score = 100 bits (239), Expect = 6e-21
Identities = 57/189 (30%), Positives = 106/189 (56%), Gaps = 1/189 (0%)
Frame = +3
Query: 153 QVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKILR 329
++G YE + IG G FA+V + ++ VA+K++ K + + + + + +E++I++
Sbjct: 4 RIGYYEIDRT--IGKGNFAVVKRATHLVTKAK-VAIKIIDKTQLDEENLKKIFREVQIMK 60
Query: 330 ELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEA 509
L H +++ ++ M++ +Y+V EY +GG++ D+L + ++E + Q+ A
Sbjct: 61 MLC---HPHIIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVTA 117
Query: 510 MSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCG 689
+ H + IVHRDLK +N+LL +++ +KIADFGF+ G + T CG
Sbjct: 118 VYFCHCRNIVHRDLKAENLLL-----------DANLNIKIADFGFSNLFTPGQLLKTWCG 166
Query: 690 SPMYMAPEV 716
SP Y APE+
Sbjct: 167 SPPYAAPEL 175
>BC074753-1|AAH74753.1| 387|Homo sapiens phosphorylase kinase,
gamma 1 (muscle) protein.
Length = 387
Score = 100 bits (239), Expect = 6e-21
Identities = 63/194 (32%), Positives = 103/194 (53%), Gaps = 9/194 (4%)
Frame = +3
Query: 165 YE-FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKG--------IQKASEILVKEI 317
YE + ++I+G G ++V + K SQ AVKV+ G +++ E +KE+
Sbjct: 17 YENYEPKEILGRGVSSVVRRCI-HKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEV 75
Query: 318 KILRELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQ 497
ILR+++ H N++ + D ++ + ++V + G+L DYL LSE + +
Sbjct: 76 DILRKVSG--HPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRA 133
Query: 498 LAEAMSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAV 677
L E + +H IVHRDLKP+NILL ++ +K+ DFGF+ LE G
Sbjct: 134 LLEVICTLHKLNIVHRDLKPENILL-----------DDNMNIKLTDFGFSCQLEPGERLR 182
Query: 678 TLCGSPMYMAPEVI 719
+CG+P Y+APE+I
Sbjct: 183 EVCGTPSYLAPEII 196
>BC069754-1|AAH69754.1| 387|Homo sapiens phosphorylase kinase,
gamma 1 (muscle) protein.
Length = 387
Score = 100 bits (239), Expect = 6e-21
Identities = 63/194 (32%), Positives = 103/194 (53%), Gaps = 9/194 (4%)
Frame = +3
Query: 165 YE-FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKG--------IQKASEILVKEI 317
YE + ++I+G G ++V + K SQ AVKV+ G +++ E +KE+
Sbjct: 17 YENYEPKEILGRGVSSVVRRCI-HKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEV 75
Query: 318 KILRELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQ 497
ILR+++ H N++ + D ++ + ++V + G+L DYL LSE + +
Sbjct: 76 DILRKVSG--HPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRA 133
Query: 498 LAEAMSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAV 677
L E + +H IVHRDLKP+NILL ++ +K+ DFGF+ LE G
Sbjct: 134 LLEVICTLHKLNIVHRDLKPENILL-----------DDNMNIKLTDFGFSCQLEPGERLR 182
Query: 678 TLCGSPMYMAPEVI 719
+CG+P Y+APE+I
Sbjct: 183 EVCGTPSYLAPEII 196
>BC069738-1|AAH69738.1| 387|Homo sapiens phosphorylase kinase,
gamma 1 (muscle) protein.
Length = 387
Score = 100 bits (239), Expect = 6e-21
Identities = 63/194 (32%), Positives = 103/194 (53%), Gaps = 9/194 (4%)
Frame = +3
Query: 165 YE-FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKG--------IQKASEILVKEI 317
YE + ++I+G G ++V + K SQ AVKV+ G +++ E +KE+
Sbjct: 17 YENYEPKEILGRGVSSVVRRCI-HKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEV 75
Query: 318 KILRELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQ 497
ILR+++ H N++ + D ++ + ++V + G+L DYL LSE + +
Sbjct: 76 DILRKVSG--HPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRA 133
Query: 498 LAEAMSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAV 677
L E + +H IVHRDLKP+NILL ++ +K+ DFGF+ LE G
Sbjct: 134 LLEVICTLHKLNIVHRDLKPENILL-----------DDNMNIKLTDFGFSCQLEPGERLR 182
Query: 678 TLCGSPMYMAPEVI 719
+CG+P Y+APE+I
Sbjct: 183 EVCGTPSYLAPEII 196
>BC069679-1|AAH69679.1| 387|Homo sapiens phosphorylase kinase,
gamma 1 (muscle) protein.
Length = 387
Score = 100 bits (239), Expect = 6e-21
Identities = 63/194 (32%), Positives = 103/194 (53%), Gaps = 9/194 (4%)
Frame = +3
Query: 165 YE-FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKG--------IQKASEILVKEI 317
YE + ++I+G G ++V + K SQ AVKV+ G +++ E +KE+
Sbjct: 17 YENYEPKEILGRGVSSVVRRCI-HKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEV 75
Query: 318 KILRELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQ 497
ILR+++ H N++ + D ++ + ++V + G+L DYL LSE + +
Sbjct: 76 DILRKVSG--HPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRA 133
Query: 498 LAEAMSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAV 677
L E + +H IVHRDLKP+NILL ++ +K+ DFGF+ LE G
Sbjct: 134 LLEVICTLHKLNIVHRDLKPENILL-----------DDNMNIKLTDFGFSCQLEPGERLR 182
Query: 678 TLCGSPMYMAPEVI 719
+CG+P Y+APE+I
Sbjct: 183 EVCGTPSYLAPEII 196
>BC051327-1|AAH51327.1| 387|Homo sapiens phosphorylase kinase,
gamma 1 (muscle) protein.
Length = 387
Score = 100 bits (239), Expect = 6e-21
Identities = 63/194 (32%), Positives = 103/194 (53%), Gaps = 9/194 (4%)
Frame = +3
Query: 165 YE-FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKG--------IQKASEILVKEI 317
YE + ++I+G G ++V + K SQ AVKV+ G +++ E +KE+
Sbjct: 17 YENYEPKEILGRGVSSVVRRCI-HKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEV 75
Query: 318 KILRELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQ 497
ILR+++ H N++ + D ++ + ++V + G+L DYL LSE + +
Sbjct: 76 DILRKVSG--HPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRA 133
Query: 498 LAEAMSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAV 677
L E + +H IVHRDLKP+NILL ++ +K+ DFGF+ LE G
Sbjct: 134 LLEVICTLHKLNIVHRDLKPENILL-----------DDNMNIKLTDFGFSCQLEPGERLR 182
Query: 678 TLCGSPMYMAPEVI 719
+CG+P Y+APE+I
Sbjct: 183 EVCGTPSYLAPEII 196
>AF254253-1|AAL36972.1| 387|Homo sapiens phosphorylase kinase gamma
protein.
Length = 387
Score = 100 bits (239), Expect = 6e-21
Identities = 63/194 (32%), Positives = 103/194 (53%), Gaps = 9/194 (4%)
Frame = +3
Query: 165 YE-FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKG--------IQKASEILVKEI 317
YE + ++I+G G ++V + K SQ AVKV+ G +++ E +KE+
Sbjct: 17 YENYEPKEILGRGVSSVVRRCI-HKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEV 75
Query: 318 KILRELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQ 497
ILR+++ H N++ + D ++ + ++V + G+L DYL LSE + +
Sbjct: 76 DILRKVSG--HPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRA 133
Query: 498 LAEAMSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAV 677
L E + +H IVHRDLKP+NILL ++ +K+ DFGF+ LE G
Sbjct: 134 LLEVICTLHKLNIVHRDLKPENILL-----------DDNMNIKLTDFGFSCQLEPGERLR 182
Query: 678 TLCGSPMYMAPEVI 719
+CG+P Y+APE+I
Sbjct: 183 EVCGTPSYLAPEII 196
>AC092101-3|AAS07453.1| 387|Homo sapiens unknown protein.
Length = 387
Score = 100 bits (239), Expect = 6e-21
Identities = 63/194 (32%), Positives = 103/194 (53%), Gaps = 9/194 (4%)
Frame = +3
Query: 165 YE-FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKG--------IQKASEILVKEI 317
YE + ++I+G G ++V + K SQ AVKV+ G +++ E +KE+
Sbjct: 17 YENYEPKEILGRGVSSVVRRCI-HKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEV 75
Query: 318 KILRELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQ 497
ILR+++ H N++ + D ++ + ++V + G+L DYL LSE + +
Sbjct: 76 DILRKVSG--HPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRA 133
Query: 498 LAEAMSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAV 677
L E + +H IVHRDLKP+NILL ++ +K+ DFGF+ LE G
Sbjct: 134 LLEVICTLHKLNIVHRDLKPENILL-----------DDNMNIKLTDFGFSCQLEPGERLR 182
Query: 678 TLCGSPMYMAPEVI 719
+CG+P Y+APE+I
Sbjct: 183 EVCGTPSYLAPEII 196
>AB023216-1|BAA76843.2| 1371|Homo sapiens KIAA0999 protein protein.
Length = 1371
Score = 100 bits (239), Expect = 6e-21
Identities = 57/189 (30%), Positives = 106/189 (56%), Gaps = 1/189 (0%)
Frame = +3
Query: 153 QVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKILR 329
++G YE + IG G FA+V + ++ VA+K++ K + + + + + +E++I++
Sbjct: 112 RIGYYEIDRT--IGKGNFAVVKRATHLVTKAK-VAIKIIDKTQLDEENLKKIFREVQIMK 168
Query: 330 ELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEA 509
L H +++ ++ M++ +Y+V EY +GG++ D+L + ++E + Q+ A
Sbjct: 169 MLC---HPHIIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVTA 225
Query: 510 MSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCG 689
+ H + IVHRDLK +N+LL +++ +KIADFGF+ G + T CG
Sbjct: 226 VYFCHCRNIVHRDLKAENLLL-----------DANLNIKIADFGFSNLFTPGQLLKTWCG 274
Query: 690 SPMYMAPEV 716
SP Y APE+
Sbjct: 275 SPPYAAPEL 283
>Z15108-1|CAA78813.1| 584|Homo sapiens protein kinase C zeta
protein.
Length = 584
Score = 99 bits (238), Expect = 8e-21
Identities = 63/190 (33%), Positives = 106/190 (55%), Gaps = 2/190 (1%)
Frame = +3
Query: 156 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI-LVKEIKILRE 332
+G +F +IG G++A V R +KN Q A+KVV K+ + +I V+ K + E
Sbjct: 239 LGLQDFDLIRVIGRGSYAKVLLVRLKKN-DQIYAMKVVKKELVHDDEDIDWVQTEKHVFE 297
Query: 333 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 512
A + LV +H C + + +++V+EY NGGDL ++Q R L E + + A++ A+
Sbjct: 298 -QASSNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIAL 356
Query: 513 SAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFAR-FLEEGNMAVTLCG 689
+ +H +GI++RDLK N+LL +D +K+ D+G + L G+ T CG
Sbjct: 357 NFLHERGIIYRDLKLDNVLL-----------DADGHIKLTDYGMCKEGLGPGDTTSTFCG 405
Query: 690 SPMYMAPEVI 719
+P Y+APE++
Sbjct: 406 TPNYIAPEIL 415
>BT007082-1|AAP35745.1| 592|Homo sapiens protein kinase C, zeta
protein.
Length = 592
Score = 99 bits (238), Expect = 8e-21
Identities = 63/190 (33%), Positives = 106/190 (55%), Gaps = 2/190 (1%)
Frame = +3
Query: 156 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI-LVKEIKILRE 332
+G +F +IG G++A V R +KN Q A+KVV K+ + +I V+ K + E
Sbjct: 247 LGLQDFDLIRVIGRGSYAKVLLVRLKKN-DQIYAMKVVKKELVHDDEDIDWVQTEKHVFE 305
Query: 333 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 512
A + LV +H C + + +++V+EY NGGDL ++Q R L E + + A++ A+
Sbjct: 306 -QASSNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIAL 364
Query: 513 SAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFAR-FLEEGNMAVTLCG 689
+ +H +GI++RDLK N+LL +D +K+ D+G + L G+ T CG
Sbjct: 365 NFLHERGIIYRDLKLDNVLL-----------DADGHIKLTDYGMCKEGLGPGDTTSTFCG 413
Query: 690 SPMYMAPEVI 719
+P Y+APE++
Sbjct: 414 TPNYIAPEIL 423
>BC014270-1|AAH14270.1| 592|Homo sapiens protein kinase C, zeta
protein.
Length = 592
Score = 99 bits (238), Expect = 8e-21
Identities = 63/190 (33%), Positives = 106/190 (55%), Gaps = 2/190 (1%)
Frame = +3
Query: 156 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI-LVKEIKILRE 332
+G +F +IG G++A V R +KN Q A+KVV K+ + +I V+ K + E
Sbjct: 247 LGLQDFDLIRVIGRGSYAKVLLVRLKKN-DQIYAMKVVKKELVHDDEDIDWVQTEKHVFE 305
Query: 333 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 512
A + LV +H C + + +++V+EY NGGDL ++Q R L E + + A++ A+
Sbjct: 306 -QASSNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIAL 364
Query: 513 SAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFAR-FLEEGNMAVTLCG 689
+ +H +GI++RDLK N+LL +D +K+ D+G + L G+ T CG
Sbjct: 365 NFLHERGIIYRDLKLDNVLL-----------DADGHIKLTDYGMCKEGLGPGDTTSTFCG 413
Query: 690 SPMYMAPEVI 719
+P Y+APE++
Sbjct: 414 TPNYIAPEIL 423
>BC008058-1|AAH08058.1| 592|Homo sapiens protein kinase C, zeta
protein.
Length = 592
Score = 99 bits (238), Expect = 8e-21
Identities = 63/190 (33%), Positives = 106/190 (55%), Gaps = 2/190 (1%)
Frame = +3
Query: 156 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI-LVKEIKILRE 332
+G +F +IG G++A V R +KN Q A+KVV K+ + +I V+ K + E
Sbjct: 247 LGLQDFDLIRVIGRGSYAKVLLVRLKKN-DQIYAMKVVKKELVHDDEDIDWVQTEKHVFE 305
Query: 333 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 512
A + LV +H C + + +++V+EY NGGDL ++Q R L E + + A++ A+
Sbjct: 306 -QASSNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIAL 364
Query: 513 SAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFAR-FLEEGNMAVTLCG 689
+ +H +GI++RDLK N+LL +D +K+ D+G + L G+ T CG
Sbjct: 365 NFLHERGIIYRDLKLDNVLL-----------DADGHIKLTDYGMCKEGLGPGDTTSTFCG 413
Query: 690 SPMYMAPEVI 719
+P Y+APE++
Sbjct: 414 TPNYIAPEIL 423
>AL645703-1|CAI21535.1| 592|Homo sapiens protein kinase C, zeta
protein.
Length = 592
Score = 99 bits (238), Expect = 8e-21
Identities = 63/190 (33%), Positives = 106/190 (55%), Gaps = 2/190 (1%)
Frame = +3
Query: 156 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI-LVKEIKILRE 332
+G +F +IG G++A V R +KN Q A+KVV K+ + +I V+ K + E
Sbjct: 247 LGLQDFDLIRVIGRGSYAKVLLVRLKKN-DQIYAMKVVKKELVHDDEDIDWVQTEKHVFE 305
Query: 333 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 512
A + LV +H C + + +++V+EY NGGDL ++Q R L E + + A++ A+
Sbjct: 306 -QASSNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIAL 364
Query: 513 SAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFAR-FLEEGNMAVTLCG 689
+ +H +GI++RDLK N+LL +D +K+ D+G + L G+ T CG
Sbjct: 365 NFLHERGIIYRDLKLDNVLL-----------DADGHIKLTDYGMCKEGLGPGDTTSTFCG 413
Query: 690 SPMYMAPEVI 719
+P Y+APE++
Sbjct: 414 TPNYIAPEIL 423
>AL590822-9|CAI12484.1| 592|Homo sapiens protein kinase C, zeta
protein.
Length = 592
Score = 99 bits (238), Expect = 8e-21
Identities = 63/190 (33%), Positives = 106/190 (55%), Gaps = 2/190 (1%)
Frame = +3
Query: 156 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI-LVKEIKILRE 332
+G +F +IG G++A V R +KN Q A+KVV K+ + +I V+ K + E
Sbjct: 247 LGLQDFDLIRVIGRGSYAKVLLVRLKKN-DQIYAMKVVKKELVHDDEDIDWVQTEKHVFE 305
Query: 333 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 512
A + LV +H C + + +++V+EY NGGDL ++Q R L E + + A++ A+
Sbjct: 306 -QASSNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIAL 364
Query: 513 SAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFAR-FLEEGNMAVTLCG 689
+ +H +GI++RDLK N+LL +D +K+ D+G + L G+ T CG
Sbjct: 365 NFLHERGIIYRDLKLDNVLL-----------DADGHIKLTDYGMCKEGLGPGDTTSTFCG 413
Query: 690 SPMYMAPEVI 719
+P Y+APE++
Sbjct: 414 TPNYIAPEIL 423
>AL391845-5|CAI15438.1| 592|Homo sapiens protein kinase C, zeta
protein.
Length = 592
Score = 99 bits (238), Expect = 8e-21
Identities = 63/190 (33%), Positives = 106/190 (55%), Gaps = 2/190 (1%)
Frame = +3
Query: 156 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI-LVKEIKILRE 332
+G +F +IG G++A V R +KN Q A+KVV K+ + +I V+ K + E
Sbjct: 247 LGLQDFDLIRVIGRGSYAKVLLVRLKKN-DQIYAMKVVKKELVHDDEDIDWVQTEKHVFE 305
Query: 333 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 512
A + LV +H C + + +++V+EY NGGDL ++Q R L E + + A++ A+
Sbjct: 306 -QASSNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIAL 364
Query: 513 SAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFAR-FLEEGNMAVTLCG 689
+ +H +GI++RDLK N+LL +D +K+ D+G + L G+ T CG
Sbjct: 365 NFLHERGIIYRDLKLDNVLL-----------DADGHIKLTDYGMCKEGLGPGDTTSTFCG 413
Query: 690 SPMYMAPEVI 719
+P Y+APE++
Sbjct: 414 TPNYIAPEIL 423
>AB088047-1|BAC03375.1| 752|Homo sapiens microtubule
affinity-regulating kinase-like1 protein.
Length = 752
Score = 99 bits (238), Expect = 8e-21
Identities = 62/188 (32%), Positives = 101/188 (53%), Gaps = 1/188 (0%)
Frame = +3
Query: 156 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKILRE 332
VG+Y + IG G A V R + VA+K++ K + +S + L +E++I++
Sbjct: 56 VGNYRLLRT--IGKGNSAKVKLARHILT-GREVAIKIIDKTQLNPSSLQKLFREVRIMK- 111
Query: 333 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 512
L H N+V + + +++ +Y+VMEY + G++ DYL ++ + E + Q+ A+
Sbjct: 112 --GLNHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAV 169
Query: 513 SAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGS 692
H K IVHRDLK +N+LL ++ +KIADFGF+ G+ T CGS
Sbjct: 170 HYCHQKNIVHRDLKAENLLL-----------DAEANIKIADFGFSNEFTLGSKLDTFCGS 218
Query: 693 PMYMAPEV 716
P Y APE+
Sbjct: 219 PPYAAPEL 226
>AB049127-1|BAB39380.1| 688|Homo sapiens MAP/microtubule
affinity-regulating kinase like 1 protein.
Length = 688
Score = 99 bits (238), Expect = 8e-21
Identities = 62/188 (32%), Positives = 101/188 (53%), Gaps = 1/188 (0%)
Frame = +3
Query: 156 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-EILVKEIKILRE 332
VG+Y + IG G A V R + VA+K++ K + +S + L +E++I++
Sbjct: 56 VGNYRLLRT--IGKGNSAKVKLARHILT-GREVAIKIIDKTQLNPSSLQKLFREVRIMK- 111
Query: 333 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 512
L H N+V + + +++ +Y+VMEY + G++ DYL ++ + E + Q+ A+
Sbjct: 112 --GLNHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAV 169
Query: 513 SAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGS 692
H K IVHRDLK +N+LL ++ +KIADFGF+ G+ T CGS
Sbjct: 170 HYCHQKNIVHRDLKAENLLL-----------DAEANIKIADFGFSNEFTLGSKLDTFCGS 218
Query: 693 PMYMAPEV 716
P Y APE+
Sbjct: 219 PPYAAPEL 226
>L14283-1|AAA36488.1| 592|Homo sapiens protein kinase C zeta
protein.
Length = 592
Score = 99.5 bits (237), Expect = 1e-20
Identities = 63/190 (33%), Positives = 105/190 (55%), Gaps = 2/190 (1%)
Frame = +3
Query: 156 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI-LVKEIKILRE 332
+G +F +IG G +A V R +KN Q A+KVV K+ + +I V+ K + E
Sbjct: 247 LGLQDFDLIRVIGRGTYAKVLLVRLKKN-DQIYAMKVVKKELVHDDEDIDWVQTEKHVFE 305
Query: 333 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 512
A + LV +H C + + +++V+EY NGGDL ++Q R L E + + A++ A+
Sbjct: 306 -QASSNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIAL 364
Query: 513 SAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFAR-FLEEGNMAVTLCG 689
+ +H +GI++RDLK N+LL +D +K+ D+G + L G+ T CG
Sbjct: 365 NFLHERGIIYRDLKLDNVLL-----------DADGHIKLTDYGMCKEGLGPGDTTSTFCG 413
Query: 690 SPMYMAPEVI 719
+P Y+APE++
Sbjct: 414 TPNYIAPEIL 423
>Y11950-1|CAA72694.1| 406|Homo sapiens phosphorylase kinase gamma
subunit protein.
Length = 406
Score = 99.1 bits (236), Expect = 1e-20
Identities = 59/191 (30%), Positives = 104/191 (54%), Gaps = 7/191 (3%)
Frame = +3
Query: 168 EFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVV-------TKKGIQKASEILVKEIKIL 326
++ +D+IG G ++V + R AVK++ + + +++ E +E IL
Sbjct: 23 KYDPKDVIGRGVSSVVRRCVHRAT-GHEFAVKIMEVTAERLSPEQLEEVREATRRETHIL 81
Query: 327 RELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAE 506
R++ H +++ + D +S +++++V + G+L DYL LSE + + L E
Sbjct: 82 RQVAG--HPHIITLIDSYESSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMRSLLE 139
Query: 507 AMSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLC 686
A+S +HA IVHRDLKP+NILL ++ ++++DFGF+ LE G LC
Sbjct: 140 AVSFLHANNIVHRDLKPENILL-----------DDNMQIRLSDFGFSCHLEPGEKLRELC 188
Query: 687 GSPMYMAPEVI 719
G+P Y+APE++
Sbjct: 189 GTPGYLAPEIL 199
>M31606-1|AAA36442.1| 406|Homo sapiens phosphorylase kinase
protein.
Length = 406
Score = 99.1 bits (236), Expect = 1e-20
Identities = 59/191 (30%), Positives = 104/191 (54%), Gaps = 7/191 (3%)
Frame = +3
Query: 168 EFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVV-------TKKGIQKASEILVKEIKIL 326
++ +D+IG G ++V + R AVK++ + + +++ E +E IL
Sbjct: 23 KYDPKDVIGRGVSSVVRRCVHRAT-GHEFAVKIMEVTAERLSPEQLEEVREATRRETHIL 81
Query: 327 RELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAE 506
R++ H +++ + D +S +++++V + G+L DYL LSE + + L E
Sbjct: 82 RQVAG--HPHIITLIDSYESSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMRSLLE 139
Query: 507 AMSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLC 686
A+S +HA IVHRDLKP+NILL ++ ++++DFGF+ LE G LC
Sbjct: 140 AVSFLHANNIVHRDLKPENILL-----------DDNMQIRLSDFGFSCHLEPGEKLRELC 188
Query: 687 GSPMYMAPEVI 719
G+P Y+APE++
Sbjct: 189 GTPGYLAPEIL 199
>BC002541-1|AAH02541.1| 406|Homo sapiens phosphorylase kinase,
gamma 2 (testis) protein.
Length = 406
Score = 99.1 bits (236), Expect = 1e-20
Identities = 59/191 (30%), Positives = 104/191 (54%), Gaps = 7/191 (3%)
Frame = +3
Query: 168 EFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVV-------TKKGIQKASEILVKEIKIL 326
++ +D+IG G ++V + R AVK++ + + +++ E +E IL
Sbjct: 23 KYDPKDVIGRGVSSVVRRCVHRAT-GHEFAVKIMEVTAERLSPEQLEEVREATRRETHIL 81
Query: 327 RELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAE 506
R++ H +++ + D +S +++++V + G+L DYL LSE + + L E
Sbjct: 82 RQVAG--HPHIITLIDSYESSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMRSLLE 139
Query: 507 AMSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLC 686
A+S +HA IVHRDLKP+NILL ++ ++++DFGF+ LE G LC
Sbjct: 140 AVSFLHANNIVHRDLKPENILL-----------DDNMQIRLSDFGFSCHLEPGEKLRELC 188
Query: 687 GSPMYMAPEVI 719
G+P Y+APE++
Sbjct: 189 GTPGYLAPEIL 199
>AY505124-1|AAS86442.1| 778|Homo sapiens protein kinase SAD-B
protein.
Length = 778
Score = 99.1 bits (236), Expect = 1e-20
Identities = 60/188 (31%), Positives = 98/188 (52%)
Frame = +3
Query: 156 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILREL 335
VG Y K +G G +V G Q VA+K+V ++ + ++ +L+K + + L
Sbjct: 31 VGPYRLEKT--LGKGQTGLVKLG-VHCITGQKVAIKIVNREKLSES--VLMKVEREIAIL 85
Query: 336 TALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMS 515
++H +++ +HD ++ Y+Y+V+E+ +GG+L DYL L+ + F Q+ A+
Sbjct: 86 KLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALD 145
Query: 516 AIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSP 695
H+ I HRDLKP+N+LL ++IADFG A ++ T CGSP
Sbjct: 146 FCHSYSICHRDLKPENLLLDEK-----------NNIRIADFGMASLQVGDSLLETSCGSP 194
Query: 696 MYMAPEVI 719
Y PEVI
Sbjct: 195 HYACPEVI 202
>AY458602-1|AAS10354.1| 778|Homo sapiens SAD1 kinase protein.
Length = 778
Score = 99.1 bits (236), Expect = 1e-20
Identities = 60/188 (31%), Positives = 98/188 (52%)
Frame = +3
Query: 156 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILREL 335
VG Y K +G G +V G Q VA+K+V ++ + ++ +L+K + + L
Sbjct: 31 VGPYRLEKT--LGKGQTGLVKLG-VHCITGQKVAIKIVNREKLSES--VLMKVEREIAIL 85
Query: 336 TALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMS 515
++H +++ +HD ++ Y+Y+V+E+ +GG+L DYL L+ + F Q+ A+
Sbjct: 86 KLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALD 145
Query: 516 AIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSP 695
H+ I HRDLKP+N+LL ++IADFG A ++ T CGSP
Sbjct: 146 FCHSYSICHRDLKPENLLLDEK-----------NNIRIADFGMASLQVGDSLLETSCGSP 194
Query: 696 MYMAPEVI 719
Y PEVI
Sbjct: 195 HYACPEVI 202
>AK131198-1|BAD18393.1| 706|Homo sapiens protein ( Homo sapiens
cDNA FLJ16039 fis, clone ADRGL2001554, weakly similar
to SERINE/THREONINE-PROTEIN KINASE PLK (EC 2.7.1.-). ).
Length = 706
Score = 99.1 bits (236), Expect = 1e-20
Identities = 65/191 (34%), Positives = 100/191 (52%), Gaps = 1/191 (0%)
Frame = +3
Query: 156 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILREL 335
V Y KQ IG G FA+VY+ + + A KVV K G+ K + L K + +R
Sbjct: 36 VDRYRVGKQ--IGKGGFAIVYELTSIRT-GKKYAGKVVEKAGLTKP-KYLEKFMSEIRIH 91
Query: 336 TALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMS 515
+L H ++ M+ + Y Y+++E C+ LA L+ L+E +Q FL Q+ +A+S
Sbjct: 92 QSLDHPHICKMYKHFEDNRYHYLILELCSNETLAHLLRVRECLTEPEVQYFLLQIIDAVS 151
Query: 516 AIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGN-MAVTLCGS 692
+H + I+HRDLK NI L ++ +K+ D G A L E N T+CG+
Sbjct: 152 YLHKRCIIHRDLKLGNIFL-----------DENLEVKVGDLGLAAQLNEPNERKKTMCGT 200
Query: 693 PMYMAPEVIMS 725
P Y+APE++ S
Sbjct: 201 PNYIAPEILQS 211
>AF479827-1|AAL87698.1| 778|Homo sapiens protein kinase-like
protein protein.
Length = 778
Score = 99.1 bits (236), Expect = 1e-20
Identities = 60/188 (31%), Positives = 98/188 (52%)
Frame = +3
Query: 156 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILREL 335
VG Y K +G G +V G Q VA+K+V ++ + ++ +L+K + + L
Sbjct: 31 VGPYRLEKT--LGKGQTGLVKLG-VHCITGQKVAIKIVNREKLSES--VLMKVEREIAIL 85
Query: 336 TALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMS 515
++H +++ +HD ++ Y+Y+V+E+ +GG+L DYL L+ + F Q+ A+
Sbjct: 86 KLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALD 145
Query: 516 AIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSP 695
H+ I HRDLKP+N+LL ++IADFG A ++ T CGSP
Sbjct: 146 FCHSYSICHRDLKPENLLLDEK-----------NNIRIADFGMASLQVGDSLLETSCGSP 194
Query: 696 MYMAPEVI 719
Y PEVI
Sbjct: 195 HYACPEVI 202
>AF479826-1|AAL87697.1| 794|Homo sapiens putative serine/threonine
protein kinase protein.
Length = 794
Score = 99.1 bits (236), Expect = 1e-20
Identities = 60/188 (31%), Positives = 98/188 (52%)
Frame = +3
Query: 156 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILREL 335
VG Y K +G G +V G Q VA+K+V ++ + ++ +L+K + + L
Sbjct: 47 VGPYRLEKT--LGKGQTGLVKLG-VHCITGQKVAIKIVNREKLSES--VLMKVEREIAIL 101
Query: 336 TALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMS 515
++H +++ +HD ++ Y+Y+V+E+ +GG+L DYL L+ + F Q+ A+
Sbjct: 102 KLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALD 161
Query: 516 AIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSP 695
H+ I HRDLKP+N+LL ++IADFG A ++ T CGSP
Sbjct: 162 FCHSYSICHRDLKPENLLLDEK-----------NNIRIADFGMASLQVGDSLLETSCGSP 210
Query: 696 MYMAPEVI 719
Y PEVI
Sbjct: 211 HYACPEVI 218
>Z84486-1|CAI21678.1| 526|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 526
Score = 98.7 bits (235), Expect = 2e-20
Identities = 66/189 (34%), Positives = 99/189 (52%), Gaps = 3/189 (1%)
Frame = +3
Query: 162 DYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI--LVKEIKILREL 335
D+ F K +IG G+F V R K AVKV+ KK I K E ++ E +L L
Sbjct: 192 DFHFLK--VIGKGSFGKVLLAR-HKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVL--L 246
Query: 336 TALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMS 515
++H LV +H + +Y V++Y NGG+L +LQ R E + + A++A A+
Sbjct: 247 KNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALG 306
Query: 516 AIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFAR-FLEEGNMAVTLCGS 692
+H+ IV+RDLKP+NILL S + + DFG + +E + T CG+
Sbjct: 307 YLHSLNIVYRDLKPENILL-----------DSQGHIVLTDFGLCKENIEHNSTTSTFCGT 355
Query: 693 PMYMAPEVI 719
P Y+APEV+
Sbjct: 356 PEYLAPEVL 364
>Y10032-1|CAA71138.1| 431|Homo sapiens serine/threonine protein
kinase protein.
Length = 431
Score = 98.7 bits (235), Expect = 2e-20
Identities = 66/189 (34%), Positives = 99/189 (52%), Gaps = 3/189 (1%)
Frame = +3
Query: 162 DYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI--LVKEIKILREL 335
D+ F K +IG G+F V R K AVKV+ KK I K E ++ E +L L
Sbjct: 97 DFHFLK--VIGKGSFGKVLLAR-HKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVL--L 151
Query: 336 TALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMS 515
++H LV +H + +Y V++Y NGG+L +LQ R E + + A++A A+
Sbjct: 152 KNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALG 211
Query: 516 AIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFAR-FLEEGNMAVTLCGS 692
+H+ IV+RDLKP+NILL S + + DFG + +E + T CG+
Sbjct: 212 YLHSLNIVYRDLKPENILL-----------DSQGHIVLTDFGLCKENIEHNSTTSTFCGT 260
Query: 693 PMYMAPEVI 719
P Y+APEV+
Sbjct: 261 PEYLAPEVL 269
>L33881-1|AAB17011.1| 587|Homo sapiens protein kinase C iota
protein.
Length = 587
Score = 98.7 bits (235), Expect = 2e-20
Identities = 62/190 (32%), Positives = 105/190 (55%), Gaps = 2/190 (1%)
Frame = +3
Query: 156 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI-LVKEIKILRE 332
+G +F +IG G++A V R +K + A+KVV K+ + +I V+ K + E
Sbjct: 240 LGLQDFDLLRVIGRGSYAKVLLVRLKKT-DRIYAMKVVKKELVNDDEDIDWVQTEKHVFE 298
Query: 333 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 512
A H LV +H C + + ++ V+EY NGGDL ++Q R L E + + A+++ A+
Sbjct: 299 -QASNHPFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQRKLPEEHARFYSAEISLAL 357
Query: 513 SAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFAR-FLEEGNMAVTLCG 689
+ +H +GI++RDLK N+LL S+ +K+ D+G + L G+ T CG
Sbjct: 358 NYLHERGIIYRDLKLDNVLL-----------DSEGHIKLTDYGMCKEGLRPGDTTSTFCG 406
Query: 690 SPMYMAPEVI 719
+P Y+APE++
Sbjct: 407 TPNYIAPEIL 416
>L18964-1|AAA60171.1| 587|Homo sapiens protein kinase C iota
protein.
Length = 587
Score = 98.7 bits (235), Expect = 2e-20
Identities = 62/190 (32%), Positives = 105/190 (55%), Gaps = 2/190 (1%)
Frame = +3
Query: 156 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI-LVKEIKILRE 332
+G +F +IG G++A V R +K + A+KVV K+ + +I V+ K + E
Sbjct: 240 LGLQDFDLLRVIGRGSYAKVLLVRLKKT-DRIYAMKVVKKELVNDDEDIDWVQTEKHVFE 298
Query: 333 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 512
A H LV +H C + + ++ V+EY NGGDL ++Q R L E + + A+++ A+
Sbjct: 299 -QASNHPFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQRKLPEEHARFYSAEISLAL 357
Query: 513 SAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFAR-FLEEGNMAVTLCG 689
+ +H +GI++RDLK N+LL S+ +K+ D+G + L G+ T CG
Sbjct: 358 NYLHERGIIYRDLKLDNVLL-----------DSEGHIKLTDYGMCKEGLRPGDTTSTFCG 406
Query: 690 SPMYMAPEVI 719
+P Y+APE++
Sbjct: 407 TPNYIAPEIL 416
>BC022016-1|AAH22016.3| 587|Homo sapiens protein kinase C, iota
protein.
Length = 587
Score = 98.7 bits (235), Expect = 2e-20
Identities = 62/190 (32%), Positives = 105/190 (55%), Gaps = 2/190 (1%)
Frame = +3
Query: 156 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI-LVKEIKILRE 332
+G +F +IG G++A V R +K + A+KVV K+ + +I V+ K + E
Sbjct: 240 LGLQDFDLLRVIGRGSYAKVLLVRLKKT-DRIYAMKVVKKELVNDDEDIDWVQTEKHVFE 298
Query: 333 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 512
A H LV +H C + + ++ V+EY NGGDL ++Q R L E + + A+++ A+
Sbjct: 299 -QASNHPFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQRKLPEEHARFYSAEISLAL 357
Query: 513 SAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFAR-FLEEGNMAVTLCG 689
+ +H +GI++RDLK N+LL S+ +K+ D+G + L G+ T CG
Sbjct: 358 NYLHERGIIYRDLKLDNVLL-----------DSEGHIKLTDYGMCKEGLRPGDTTSTFCG 406
Query: 690 SPMYMAPEVI 719
+P Y+APE++
Sbjct: 407 TPNYIAPEIL 416
>BC001263-1|AAH01263.1| 431|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 431
Score = 98.7 bits (235), Expect = 2e-20
Identities = 66/189 (34%), Positives = 99/189 (52%), Gaps = 3/189 (1%)
Frame = +3
Query: 162 DYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI--LVKEIKILREL 335
D+ F K +IG G+F V R K AVKV+ KK I K E ++ E +L L
Sbjct: 97 DFHFLK--VIGKGSFGKVLLAR-HKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVL--L 151
Query: 336 TALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMS 515
++H LV +H + +Y V++Y NGG+L +LQ R E + + A++A A+
Sbjct: 152 KNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALG 211
Query: 516 AIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFAR-FLEEGNMAVTLCGS 692
+H+ IV+RDLKP+NILL S + + DFG + +E + T CG+
Sbjct: 212 YLHSLNIVYRDLKPENILL-----------DSQGHIVLTDFGLCKENIEHNSTTSTFCGT 260
Query: 693 PMYMAPEVI 719
P Y+APEV+
Sbjct: 261 PEYLAPEVL 269
>AY505125-1|AAS86443.1| 696|Homo sapiens protein kinase SAD-A
protein.
Length = 696
Score = 98.7 bits (235), Expect = 2e-20
Identities = 60/188 (31%), Positives = 98/188 (52%)
Frame = +3
Query: 156 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILREL 335
VG Y K +G G +V G Q VA+K+V ++ + ++ +L+K + + L
Sbjct: 16 VGPYRLEKT--LGKGQTGLVKLGVHCVT-CQKVAIKIVNREKLSES--VLMKVEREIAIL 70
Query: 336 TALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMS 515
++H +++ +HD ++ Y+Y+V+E+ +GG+L DYL L+ + F Q+ A+
Sbjct: 71 KLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALD 130
Query: 516 AIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSP 695
H+ I HRDLKP+N+LL ++IADFG A ++ T CGSP
Sbjct: 131 FCHSHSICHRDLKPENLLLDEK-----------NNIRIADFGMASLQVGDSLLETSCGSP 179
Query: 696 MYMAPEVI 719
Y PEVI
Sbjct: 180 HYACPEVI 187
>AY166857-1|AAN87839.1| 668|Homo sapiens serine/threonine protein
kinase isoform protein.
Length = 668
Score = 98.7 bits (235), Expect = 2e-20
Identities = 60/188 (31%), Positives = 98/188 (52%)
Frame = +3
Query: 156 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILREL 335
VG Y K +G G +V G Q VA+K+V ++ + ++ +L+K + + L
Sbjct: 16 VGPYRLEKT--LGKGQTGLVKLGVHCVT-CQKVAIKIVNREKLSES--VLMKVEREIAIL 70
Query: 336 TALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMS 515
++H +++ +HD ++ Y+Y+V+E+ +GG+L DYL L+ + F Q+ A+
Sbjct: 71 KLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALD 130
Query: 516 AIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSP 695
H+ I HRDLKP+N+LL ++IADFG A ++ T CGSP
Sbjct: 131 FCHSHSICHRDLKPENLLLDEK-----------NNIRIADFGMASLQVGDSLLETSCGSP 179
Query: 696 MYMAPEVI 719
Y PEVI
Sbjct: 180 HYACPEVI 187
>AL355881-2|CAH72579.1| 526|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 526
Score = 98.7 bits (235), Expect = 2e-20
Identities = 66/189 (34%), Positives = 99/189 (52%), Gaps = 3/189 (1%)
Frame = +3
Query: 162 DYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI--LVKEIKILREL 335
D+ F K +IG G+F V R K AVKV+ KK I K E ++ E +L L
Sbjct: 192 DFHFLK--VIGKGSFGKVLLAR-HKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVL--L 246
Query: 336 TALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMS 515
++H LV +H + +Y V++Y NGG+L +LQ R E + + A++A A+
Sbjct: 247 KNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALG 306
Query: 516 AIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFAR-FLEEGNMAVTLCGS 692
+H+ IV+RDLKP+NILL S + + DFG + +E + T CG+
Sbjct: 307 YLHSLNIVYRDLKPENILL-----------DSQGHIVLTDFGLCKENIEHNSTTSTFCGT 355
Query: 693 PMYMAPEVI 719
P Y+APEV+
Sbjct: 356 PEYLAPEVL 364
>AL135839-4|CAI19721.1| 526|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 526
Score = 98.7 bits (235), Expect = 2e-20
Identities = 66/189 (34%), Positives = 99/189 (52%), Gaps = 3/189 (1%)
Frame = +3
Query: 162 DYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI--LVKEIKILREL 335
D+ F K +IG G+F V R K AVKV+ KK I K E ++ E +L L
Sbjct: 192 DFHFLK--VIGKGSFGKVLLAR-HKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVL--L 246
Query: 336 TALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMS 515
++H LV +H + +Y V++Y NGG+L +LQ R E + + A++A A+
Sbjct: 247 KNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALG 306
Query: 516 AIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFAR-FLEEGNMAVTLCGS 692
+H+ IV+RDLKP+NILL S + + DFG + +E + T CG+
Sbjct: 307 YLHSLNIVYRDLKPENILL-----------DSQGHIVLTDFGLCKENIEHNSTTSTFCGT 355
Query: 693 PMYMAPEVI 719
P Y+APEV+
Sbjct: 356 PEYLAPEVL 364
>AL135839-3|CAI19720.1| 445|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 445
Score = 98.7 bits (235), Expect = 2e-20
Identities = 66/189 (34%), Positives = 99/189 (52%), Gaps = 3/189 (1%)
Frame = +3
Query: 162 DYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI--LVKEIKILREL 335
D+ F K +IG G+F V R K AVKV+ KK I K E ++ E +L L
Sbjct: 111 DFHFLK--VIGKGSFGKVLLAR-HKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVL--L 165
Query: 336 TALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMS 515
++H LV +H + +Y V++Y NGG+L +LQ R E + + A++A A+
Sbjct: 166 KNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALG 225
Query: 516 AIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFAR-FLEEGNMAVTLCGS 692
+H+ IV+RDLKP+NILL S + + DFG + +E + T CG+
Sbjct: 226 YLHSLNIVYRDLKPENILL-----------DSQGHIVLTDFGLCKENIEHNSTTSTFCGT 274
Query: 693 PMYMAPEVI 719
P Y+APEV+
Sbjct: 275 PEYLAPEVL 283
>AL135839-2|CAI19719.1| 431|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 431
Score = 98.7 bits (235), Expect = 2e-20
Identities = 66/189 (34%), Positives = 99/189 (52%), Gaps = 3/189 (1%)
Frame = +3
Query: 162 DYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI--LVKEIKILREL 335
D+ F K +IG G+F V R K AVKV+ KK I K E ++ E +L L
Sbjct: 97 DFHFLK--VIGKGSFGKVLLAR-HKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVL--L 151
Query: 336 TALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMS 515
++H LV +H + +Y V++Y NGG+L +LQ R E + + A++A A+
Sbjct: 152 KNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALG 211
Query: 516 AIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFAR-FLEEGNMAVTLCGS 692
+H+ IV+RDLKP+NILL S + + DFG + +E + T CG+
Sbjct: 212 YLHSLNIVYRDLKPENILL-----------DSQGHIVLTDFGLCKENIEHNSTTSTFCGT 260
Query: 693 PMYMAPEVI 719
P Y+APEV+
Sbjct: 261 PEYLAPEVL 269
>AL135839-1|CAI19718.1| 421|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 421
Score = 98.7 bits (235), Expect = 2e-20
Identities = 66/189 (34%), Positives = 99/189 (52%), Gaps = 3/189 (1%)
Frame = +3
Query: 162 DYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI--LVKEIKILREL 335
D+ F K +IG G+F V R K AVKV+ KK I K E ++ E +L L
Sbjct: 87 DFHFLK--VIGKGSFGKVLLAR-HKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVL--L 141
Query: 336 TALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMS 515
++H LV +H + +Y V++Y NGG+L +LQ R E + + A++A A+
Sbjct: 142 KNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALG 201
Query: 516 AIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFAR-FLEEGNMAVTLCGS 692
+H+ IV+RDLKP+NILL S + + DFG + +E + T CG+
Sbjct: 202 YLHSLNIVYRDLKPENILL-----------DSQGHIVLTDFGLCKENIEHNSTTSTFCGT 250
Query: 693 PMYMAPEVI 719
P Y+APEV+
Sbjct: 251 PEYLAPEVL 259
>AJ000512-1|CAA04146.1| 431|Homo sapiens serine/threonine protein
kinase protein.
Length = 431
Score = 98.7 bits (235), Expect = 2e-20
Identities = 66/189 (34%), Positives = 99/189 (52%), Gaps = 3/189 (1%)
Frame = +3
Query: 162 DYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI--LVKEIKILREL 335
D+ F K +IG G+F V R K AVKV+ KK I K E ++ E +L L
Sbjct: 97 DFHFLK--VIGKGSFGKVLLAR-HKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVL--L 151
Query: 336 TALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMS 515
++H LV +H + +Y V++Y NGG+L +LQ R E + + A++A A+
Sbjct: 152 KNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALG 211
Query: 516 AIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFAR-FLEEGNMAVTLCGS 692
+H+ IV+RDLKP+NILL S + + DFG + +E + T CG+
Sbjct: 212 YLHSLNIVYRDLKPENILL-----------DSQGHIVLTDFGLCKENIEHNSTTSTFCGT 260
Query: 693 PMYMAPEVI 719
P Y+APEV+
Sbjct: 261 PEYLAPEVL 269
>AF533880-1|AAP97727.1| 674|Homo sapiens putative serine/threonine
protein kinase variant B3 protein.
Length = 674
Score = 98.7 bits (235), Expect = 2e-20
Identities = 60/188 (31%), Positives = 98/188 (52%)
Frame = +3
Query: 156 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILREL 335
VG Y K +G G +V G Q VA+K+V ++ + ++ +L+K + + L
Sbjct: 16 VGPYRLEKT--LGKGQTGLVKLGVHCVT-CQKVAIKIVNREKLSES--VLMKVEREIAIL 70
Query: 336 TALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMS 515
++H +++ +HD ++ Y+Y+V+E+ +GG+L DYL L+ + F Q+ A+
Sbjct: 71 KLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALD 130
Query: 516 AIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSP 695
H+ I HRDLKP+N+LL ++IADFG A ++ T CGSP
Sbjct: 131 FCHSHSICHRDLKPENLLLDEK-----------NNIRIADFGMASLQVGDSLLETSCGSP 179
Query: 696 MYMAPEVI 719
Y PEVI
Sbjct: 180 HYACPEVI 187
>AF533879-1|AAP97726.1| 736|Homo sapiens putative serine/threonine
protein kinase variant C protein.
Length = 736
Score = 98.7 bits (235), Expect = 2e-20
Identities = 60/188 (31%), Positives = 98/188 (52%)
Frame = +3
Query: 156 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILREL 335
VG Y K +G G +V G Q VA+K+V ++ + ++ +L+K + + L
Sbjct: 16 VGPYRLEKT--LGKGQTGLVKLGVHCVT-CQKVAIKIVNREKLSES--VLMKVEREIAIL 70
Query: 336 TALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMS 515
++H +++ +HD ++ Y+Y+V+E+ +GG+L DYL L+ + F Q+ A+
Sbjct: 71 KLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALD 130
Query: 516 AIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSP 695
H+ I HRDLKP+N+LL ++IADFG A ++ T CGSP
Sbjct: 131 FCHSHSICHRDLKPENLLLDEK-----------NNIRIADFGMASLQVGDSLLETSCGSP 179
Query: 696 MYMAPEVI 719
Y PEVI
Sbjct: 180 HYACPEVI 187
>AF533878-1|AAP97725.1| 674|Homo sapiens putative serine/threonine
protein kinase variant B2 protein.
Length = 674
Score = 98.7 bits (235), Expect = 2e-20
Identities = 60/188 (31%), Positives = 98/188 (52%)
Frame = +3
Query: 156 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILREL 335
VG Y K +G G +V G Q VA+K+V ++ + ++ +L+K + + L
Sbjct: 16 VGPYRLEKT--LGKGQTGLVKLGVHCVT-CQKVAIKIVNREKLSES--VLMKVEREIAIL 70
Query: 336 TALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMS 515
++H +++ +HD ++ Y+Y+V+E+ +GG+L DYL L+ + F Q+ A+
Sbjct: 71 KLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALD 130
Query: 516 AIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSP 695
H+ I HRDLKP+N+LL ++IADFG A ++ T CGSP
Sbjct: 131 FCHSHSICHRDLKPENLLLDEK-----------NNIRIADFGMASLQVGDSLLETSCGSP 179
Query: 696 MYMAPEVI 719
Y PEVI
Sbjct: 180 HYACPEVI 187
>AF533877-1|AAP97724.1| 674|Homo sapiens putative serine/threonine
protein kinase variant B1 protein.
Length = 674
Score = 98.7 bits (235), Expect = 2e-20
Identities = 60/188 (31%), Positives = 98/188 (52%)
Frame = +3
Query: 156 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILREL 335
VG Y K +G G +V G Q VA+K+V ++ + ++ +L+K + + L
Sbjct: 16 VGPYRLEKT--LGKGQTGLVKLGVHCVT-CQKVAIKIVNREKLSES--VLMKVEREIAIL 70
Query: 336 TALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMS 515
++H +++ +HD ++ Y+Y+V+E+ +GG+L DYL L+ + F Q+ A+
Sbjct: 71 KLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALD 130
Query: 516 AIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSP 695
H+ I HRDLKP+N+LL ++IADFG A ++ T CGSP
Sbjct: 131 FCHSHSICHRDLKPENLLLDEK-----------NNIRIADFGMASLQVGDSLLETSCGSP 179
Query: 696 MYMAPEVI 719
Y PEVI
Sbjct: 180 HYACPEVI 187
>AF533876-1|AAP97723.1| 668|Homo sapiens putative serine/threonine
protein kinase variant A protein.
Length = 668
Score = 98.7 bits (235), Expect = 2e-20
Identities = 60/188 (31%), Positives = 98/188 (52%)
Frame = +3
Query: 156 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILREL 335
VG Y K +G G +V G Q VA+K+V ++ + ++ +L+K + + L
Sbjct: 16 VGPYRLEKT--LGKGQTGLVKLGVHCVT-CQKVAIKIVNREKLSES--VLMKVEREIAIL 70
Query: 336 TALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMS 515
++H +++ +HD ++ Y+Y+V+E+ +GG+L DYL L+ + F Q+ A+
Sbjct: 71 KLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALD 130
Query: 516 AIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSP 695
H+ I HRDLKP+N+LL ++IADFG A ++ T CGSP
Sbjct: 131 FCHSHSICHRDLKPENLLLDEK-----------NNIRIADFGMASLQVGDSLLETSCGSP 179
Query: 696 MYMAPEVI 719
Y PEVI
Sbjct: 180 HYACPEVI 187
>AF153609-1|AAD41091.1| 431|Homo sapiens serine/threonine protein
kinase sgk protein.
Length = 431
Score = 98.7 bits (235), Expect = 2e-20
Identities = 66/189 (34%), Positives = 99/189 (52%), Gaps = 3/189 (1%)
Frame = +3
Query: 162 DYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI--LVKEIKILREL 335
D+ F K +IG G+F V R K AVKV+ KK I K E ++ E +L L
Sbjct: 97 DFHFLK--VIGKGSFGKVLLAR-HKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVL--L 151
Query: 336 TALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMS 515
++H LV +H + +Y V++Y NGG+L +LQ R E + + A++A A+
Sbjct: 152 KNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALG 211
Query: 516 AIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFAR-FLEEGNMAVTLCGS 692
+H+ IV+RDLKP+NILL S + + DFG + +E + T CG+
Sbjct: 212 YLHSLNIVYRDLKPENILL-----------DSQGHIVLTDFGLCKENIEHNSTTSTFCGT 260
Query: 693 PMYMAPEVI 719
P Y+APEV+
Sbjct: 261 PEYLAPEVL 269
>X76104-1|CAA53712.1| 1431|Homo sapiens DAP-kinase protein.
Length = 1431
Score = 97.9 bits (233), Expect = 3e-20
Identities = 62/193 (32%), Positives = 104/193 (53%), Gaps = 5/193 (2%)
Frame = +3
Query: 156 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-----EILVKEIK 320
V DY T +++ G G FA+V K R++ Q A K + K+ + + E + +E+
Sbjct: 9 VDDYYDTGEEL-GSGQFAVVKKCREKSTGLQ-YAAKFIKKRRTKSSRRGVSREDIEREVS 66
Query: 321 ILRELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQL 500
IL+E+ QH N++ +H+ ++ V +++E GG+L D+L L+E FL Q+
Sbjct: 67 ILKEI---QHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQI 123
Query: 501 AEAMSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVT 680
+ +H+ I H DLKP+NI+L L P P +KI DFG A ++ GN
Sbjct: 124 LNGVYYLHSLQIAHFDLKPENIML----LDRNVPKP---RIKIIDFGLAHKIDFGNEFKN 176
Query: 681 LCGSPMYMAPEVI 719
+ G+P ++APE++
Sbjct: 177 IFGTPEFVAPEIV 189
>DQ436495-1|ABD96827.1| 1430|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1430
Score = 97.9 bits (233), Expect = 3e-20
Identities = 62/193 (32%), Positives = 104/193 (53%), Gaps = 5/193 (2%)
Frame = +3
Query: 156 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-----EILVKEIK 320
V DY T +++ G G FA+V K R++ Q A K + K+ + + E + +E+
Sbjct: 9 VDDYYDTGEEL-GSGQFAVVKKCREKSTGLQ-YAAKFIKKRRTKSSRRGVSREDIEREVS 66
Query: 321 ILRELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQL 500
IL+E+ QH N++ +H+ ++ V +++E GG+L D+L L+E FL Q+
Sbjct: 67 ILKEI---QHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQI 123
Query: 501 AEAMSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVT 680
+ +H+ I H DLKP+NI+L L P P +KI DFG A ++ GN
Sbjct: 124 LNGVYYLHSLQIAHFDLKPENIML----LDRNVPKP---RIKIIDFGLAHKIDFGNEFKN 176
Query: 681 LCGSPMYMAPEVI 719
+ G+P ++APE++
Sbjct: 177 IFGTPEFVAPEIV 189
>BT006935-1|AAP35581.1| 367|Homo sapiens death-associated protein
kinase 1 protein.
Length = 367
Score = 97.9 bits (233), Expect = 3e-20
Identities = 62/193 (32%), Positives = 104/193 (53%), Gaps = 5/193 (2%)
Frame = +3
Query: 156 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-----EILVKEIK 320
V DY T +++ G G FA+V K R++ Q A K + K+ + + E + +E+
Sbjct: 9 VDDYYDTGEEL-GSGQFAVVKKCREKSTGLQ-YAAKFIKKRRTKSSRRGVSREDIEREVS 66
Query: 321 ILRELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQL 500
IL+E+ QH N++ +H+ ++ V +++E GG+L D+L L+E FL Q+
Sbjct: 67 ILKEI---QHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQI 123
Query: 501 AEAMSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVT 680
+ +H+ I H DLKP+NI+L L P P +KI DFG A ++ GN
Sbjct: 124 LNGVYYLHSLQIAHFDLKPENIML----LDRNVPKP---RIKIIDFGLAHKIDFGNEFKN 176
Query: 681 LCGSPMYMAPEVI 719
+ G+P ++APE++
Sbjct: 177 IFGTPEFVAPEIV 189
>BC113660-1|AAI13661.1| 1430|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1430
Score = 97.9 bits (233), Expect = 3e-20
Identities = 62/193 (32%), Positives = 104/193 (53%), Gaps = 5/193 (2%)
Frame = +3
Query: 156 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-----EILVKEIK 320
V DY T +++ G G FA+V K R++ Q A K + K+ + + E + +E+
Sbjct: 9 VDDYYDTGEEL-GSGQFAVVKKCREKSTGLQ-YAAKFIKKRRTKSSRRGVSREDIEREVS 66
Query: 321 ILRELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQL 500
IL+E+ QH N++ +H+ ++ V +++E GG+L D+L L+E FL Q+
Sbjct: 67 ILKEI---QHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQI 123
Query: 501 AEAMSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVT 680
+ +H+ I H DLKP+NI+L L P P +KI DFG A ++ GN
Sbjct: 124 LNGVYYLHSLQIAHFDLKPENIML----LDRNVPKP---RIKIIDFGLAHKIDFGNEFKN 176
Query: 681 LCGSPMYMAPEVI 719
+ G+P ++APE++
Sbjct: 177 IFGTPEFVAPEIV 189
>AL591852-1|CAH71696.1| 1455|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1455
Score = 97.9 bits (233), Expect = 3e-20
Identities = 62/193 (32%), Positives = 104/193 (53%), Gaps = 5/193 (2%)
Frame = +3
Query: 156 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-----EILVKEIK 320
V DY T +++ G G FA+V K R++ Q A K + K+ + + E + +E+
Sbjct: 9 VDDYYDTGEEL-GSGQFAVVKKCREKSTGLQ-YAAKFIKKRRTKSSRRGVSREDIEREVS 66
Query: 321 ILRELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQL 500
IL+E+ QH N++ +H+ ++ V +++E GG+L D+L L+E FL Q+
Sbjct: 67 ILKEI---QHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQI 123
Query: 501 AEAMSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVT 680
+ +H+ I H DLKP+NI+L L P P +KI DFG A ++ GN
Sbjct: 124 LNGVYYLHSLQIAHFDLKPENIML----LDRNVPKP---RIKIIDFGLAHKIDFGNEFKN 176
Query: 681 LCGSPMYMAPEVI 719
+ G+P ++APE++
Sbjct: 177 IFGTPEFVAPEIV 189
>AL161787-1|CAH73544.1| 1455|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1455
Score = 97.9 bits (233), Expect = 3e-20
Identities = 62/193 (32%), Positives = 104/193 (53%), Gaps = 5/193 (2%)
Frame = +3
Query: 156 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-----EILVKEIK 320
V DY T +++ G G FA+V K R++ Q A K + K+ + + E + +E+
Sbjct: 9 VDDYYDTGEEL-GSGQFAVVKKCREKSTGLQ-YAAKFIKKRRTKSSRRGVSREDIEREVS 66
Query: 321 ILRELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQL 500
IL+E+ QH N++ +H+ ++ V +++E GG+L D+L L+E FL Q+
Sbjct: 67 ILKEI---QHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQI 123
Query: 501 AEAMSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVT 680
+ +H+ I H DLKP+NI+L L P P +KI DFG A ++ GN
Sbjct: 124 LNGVYYLHSLQIAHFDLKPENIML----LDRNVPKP---RIKIIDFGLAHKIDFGNEFKN 176
Query: 681 LCGSPMYMAPEVI 719
+ G+P ++APE++
Sbjct: 177 IFGTPEFVAPEIV 189
>AL160279-1|CAI16306.1| 1455|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1455
Score = 97.9 bits (233), Expect = 3e-20
Identities = 62/193 (32%), Positives = 104/193 (53%), Gaps = 5/193 (2%)
Frame = +3
Query: 156 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-----EILVKEIK 320
V DY T +++ G G FA+V K R++ Q A K + K+ + + E + +E+
Sbjct: 9 VDDYYDTGEEL-GSGQFAVVKKCREKSTGLQ-YAAKFIKKRRTKSSRRGVSREDIEREVS 66
Query: 321 ILRELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQL 500
IL+E+ QH N++ +H+ ++ V +++E GG+L D+L L+E FL Q+
Sbjct: 67 ILKEI---QHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQI 123
Query: 501 AEAMSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVT 680
+ +H+ I H DLKP+NI+L L P P +KI DFG A ++ GN
Sbjct: 124 LNGVYYLHSLQIAHFDLKPENIML----LDRNVPKP---RIKIIDFGLAHKIDFGNEFKN 176
Query: 681 LCGSPMYMAPEVI 719
+ G+P ++APE++
Sbjct: 177 IFGTPEFVAPEIV 189
>AB208871-1|BAD92108.1| 1433|Homo sapiens Hypothetical protein
DKFZp781I035 variant protein.
Length = 1433
Score = 97.9 bits (233), Expect = 3e-20
Identities = 62/193 (32%), Positives = 104/193 (53%), Gaps = 5/193 (2%)
Frame = +3
Query: 156 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKAS-----EILVKEIK 320
V DY T +++ G G FA+V K R++ Q A K + K+ + + E + +E+
Sbjct: 12 VDDYYDTGEEL-GSGQFAVVKKCREKSTGLQ-YAAKFIKKRRTKSSRRGVSREDIEREVS 69
Query: 321 ILRELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQL 500
IL+E+ QH N++ +H+ ++ V +++E GG+L D+L L+E FL Q+
Sbjct: 70 ILKEI---QHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQI 126
Query: 501 AEAMSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVT 680
+ +H+ I H DLKP+NI+L L P P +KI DFG A ++ GN
Sbjct: 127 LNGVYYLHSLQIAHFDLKPENIML----LDRNVPKP---RIKIIDFGLAHKIDFGNEFKN 179
Query: 681 LCGSPMYMAPEVI 719
+ G+P ++APE++
Sbjct: 180 IFGTPEFVAPEIV 192
>Z92868-1|CAB07437.1| 686|Homo sapiens cGMP-dependent protein
kinase type I beta protein.
Length = 686
Score = 97.5 bits (232), Expect = 4e-20
Identities = 55/187 (29%), Positives = 101/187 (54%), Gaps = 1/187 (0%)
Frame = +3
Query: 168 EFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQ 347
+F D +G G F V + + S++ A+K++ K+ I + + I+ +++
Sbjct: 374 DFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQ--QEHIRSEKQIMQGA 431
Query: 348 HKN-LVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIH 524
H + +V ++ Y+Y++ME C GG+L L+ ++T + + A + EA + +H
Sbjct: 432 HSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLH 491
Query: 525 AKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYM 704
+KGI++RDLKP+N++L H K+ DFGFA+ + G T CG+P Y+
Sbjct: 492 SKGIIYRDLKPENLILDHRGYA-----------KLVDFGFAKKIGFGKKTWTFCGTPEYV 540
Query: 705 APEVIMS 725
APE+I++
Sbjct: 541 APEIILN 547
>Z92867-1|CAB07436.1| 671|Homo sapiens cGMP-dependent protein
kinase type I alpha protein.
Length = 671
Score = 97.5 bits (232), Expect = 4e-20
Identities = 55/187 (29%), Positives = 101/187 (54%), Gaps = 1/187 (0%)
Frame = +3
Query: 168 EFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQ 347
+F D +G G F V + + S++ A+K++ K+ I + + I+ +++
Sbjct: 359 DFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQ--QEHIRSEKQIMQGA 416
Query: 348 HKN-LVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIH 524
H + +V ++ Y+Y++ME C GG+L L+ ++T + + A + EA + +H
Sbjct: 417 HSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLH 476
Query: 525 AKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYM 704
+KGI++RDLKP+N++L H K+ DFGFA+ + G T CG+P Y+
Sbjct: 477 SKGIIYRDLKPENLILDHRGYA-----------KLVDFGFAKKIGFGKKTWTFCGTPEYV 525
Query: 705 APEVIMS 725
APE+I++
Sbjct: 526 APEIILN 532
>Y13115-1|CAA73575.1| 970|Homo sapiens serine/threonine protein
kinase protein.
Length = 970
Score = 97.5 bits (232), Expect = 4e-20
Identities = 60/187 (32%), Positives = 105/187 (56%), Gaps = 4/187 (2%)
Frame = +3
Query: 168 EFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI--LVKEIKILRELTA 341
+F +++G G+FA VY+ + VA+K++ KK + KA + + E+KI +L
Sbjct: 11 DFKVGNLLGKGSFAGVYRAESI-HTGLEVAIKMIDKKAMYKAGMVQRVKNEVKIHCQL-- 67
Query: 342 LQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTN-RLLSETTIQLFLAQLAEAMSA 518
+H +++ +++ + YVY+V+E C+ G++ YL+ + SE + F+ Q+ M
Sbjct: 68 -KHPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLY 126
Query: 519 IHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLE-EGNMAVTLCGSP 695
+H+ GI+HRDL N+LLT ++ +KIADFG A L+ TLCG+P
Sbjct: 127 LHSHGILHRDLTLSNLLLTR-----------NMNIKIADFGLATQLKMPHEKHYTLCGTP 175
Query: 696 MYMAPEV 716
Y++PE+
Sbjct: 176 NYISPEI 182
>Y07512-1|CAA68810.1| 686|Homo sapiens protein ( Human mRNA for
type I beta cGMP-dependent protein kinase (EC
2.7.1.37). ).
Length = 686
Score = 97.5 bits (232), Expect = 4e-20
Identities = 55/187 (29%), Positives = 101/187 (54%), Gaps = 1/187 (0%)
Frame = +3
Query: 168 EFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQ 347
+F D +G G F V + + S++ A+K++ K+ I + + I+ +++
Sbjct: 374 DFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQ--QEHIRSEKQIMQGA 431
Query: 348 HKN-LVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIH 524
H + +V ++ Y+Y++ME C GG+L L+ ++T + + A + EA + +H
Sbjct: 432 HSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLH 491
Query: 525 AKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYM 704
+KGI++RDLKP+N++L H K+ DFGFA+ + G T CG+P Y+
Sbjct: 492 SKGIIYRDLKPENLILDHRGYA-----------KLVDFGFAKKIGFGKKTWTFCGTPEYV 540
Query: 705 APEVIMS 725
APE+I++
Sbjct: 541 APEIILN 547
>D45864-1|BAA08297.1| 671|Homo sapiens cGMP-dependent protein
kinase type I alpha protein.
Length = 671
Score = 97.5 bits (232), Expect = 4e-20
Identities = 55/187 (29%), Positives = 101/187 (54%), Gaps = 1/187 (0%)
Frame = +3
Query: 168 EFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQ 347
+F D +G G F V + + S++ A+K++ K+ I + + I+ +++
Sbjct: 359 DFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQ--QEHIRSEKQIMQGA 416
Query: 348 HKN-LVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIH 524
H + +V ++ Y+Y++ME C GG+L L+ ++T + + A + EA + +H
Sbjct: 417 HSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLH 476
Query: 525 AKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYM 704
+KGI++RDLKP+N++L H K+ DFGFA+ + G T CG+P Y+
Sbjct: 477 SKGIIYRDLKPENLILDHRGYA-----------KLVDFGFAKKIGFGKKTWTFCGTPEYV 525
Query: 705 APEVIMS 725
APE+I++
Sbjct: 526 APEIILN 532
>BC127090-1|AAI27091.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 97.5 bits (232), Expect = 4e-20
Identities = 55/187 (29%), Positives = 101/187 (54%), Gaps = 1/187 (0%)
Frame = +3
Query: 168 EFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQ 347
+F D +G G F V + + S++ A+K++ K+ I + + I+ +++
Sbjct: 374 DFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQ--QEHIRSEKQIMQGA 431
Query: 348 HKN-LVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIH 524
H + +V ++ Y+Y++ME C GG+L L+ ++T + + A + EA + +H
Sbjct: 432 HSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLH 491
Query: 525 AKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYM 704
+KGI++RDLKP+N++L H K+ DFGFA+ + G T CG+P Y+
Sbjct: 492 SKGIIYRDLKPENLILDHRGYA-----------KLVDFGFAKKIGFGKKTWTFCGTPEYV 540
Query: 705 APEVIMS 725
APE+I++
Sbjct: 541 APEIILN 547
>BC036023-1|AAH36023.1| 970|Homo sapiens polo-like kinase 4
(Drosophila) protein.
Length = 970
Score = 97.5 bits (232), Expect = 4e-20
Identities = 60/187 (32%), Positives = 105/187 (56%), Gaps = 4/187 (2%)
Frame = +3
Query: 168 EFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI--LVKEIKILRELTA 341
+F +++G G+FA VY+ + VA+K++ KK + KA + + E+KI +L
Sbjct: 11 DFKVGNLLGKGSFAGVYRAESI-HTGLEVAIKMIDKKAMYKAGMVQRVQNEVKIHCQL-- 67
Query: 342 LQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTN-RLLSETTIQLFLAQLAEAMSA 518
+H +++ +++ + YVY+V+E C+ G++ YL+ + SE + F+ Q+ M
Sbjct: 68 -KHPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLY 126
Query: 519 IHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLE-EGNMAVTLCGSP 695
+H+ GI+HRDL N+LLT ++ +KIADFG A L+ TLCG+P
Sbjct: 127 LHSHGILHRDLTLSNLLLTR-----------NMNIKIADFGLATQLKMPHEKHYTLCGTP 175
Query: 696 MYMAPEV 716
Y++PE+
Sbjct: 176 NYISPEI 182
>AL928686-2|CAI40743.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 97.5 bits (232), Expect = 4e-20
Identities = 55/187 (29%), Positives = 101/187 (54%), Gaps = 1/187 (0%)
Frame = +3
Query: 168 EFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQ 347
+F D +G G F V + + S++ A+K++ K+ I + + I+ +++
Sbjct: 374 DFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQ--QEHIRSEKQIMQGA 431
Query: 348 HKN-LVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIH 524
H + +V ++ Y+Y++ME C GG+L L+ ++T + + A + EA + +H
Sbjct: 432 HSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLH 491
Query: 525 AKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYM 704
+KGI++RDLKP+N++L H K+ DFGFA+ + G T CG+P Y+
Sbjct: 492 SKGIIYRDLKPENLILDHRGYA-----------KLVDFGFAKKIGFGKKTWTFCGTPEYV 540
Query: 705 APEVIMS 725
APE+I++
Sbjct: 541 APEIILN 547
>AL928686-1|CAI40742.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 97.5 bits (232), Expect = 4e-20
Identities = 55/187 (29%), Positives = 101/187 (54%), Gaps = 1/187 (0%)
Frame = +3
Query: 168 EFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQ 347
+F D +G G F V + + S++ A+K++ K+ I + + I+ +++
Sbjct: 347 DFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQ--QEHIRSEKQIMQGA 404
Query: 348 HKN-LVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIH 524
H + +V ++ Y+Y++ME C GG+L L+ ++T + + A + EA + +H
Sbjct: 405 HSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLH 464
Query: 525 AKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYM 704
+KGI++RDLKP+N++L H K+ DFGFA+ + G T CG+P Y+
Sbjct: 465 SKGIIYRDLKPENLILDHRGYA-----------KLVDFGFAKKIGFGKKTWTFCGTPEYV 513
Query: 705 APEVIMS 725
APE+I++
Sbjct: 514 APEIILN 520
>AL731537-3|CAI17115.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 97.5 bits (232), Expect = 4e-20
Identities = 55/187 (29%), Positives = 101/187 (54%), Gaps = 1/187 (0%)
Frame = +3
Query: 168 EFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQ 347
+F D +G G F V + + S++ A+K++ K+ I + + I+ +++
Sbjct: 374 DFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQ--QEHIRSEKQIMQGA 431
Query: 348 HKN-LVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIH 524
H + +V ++ Y+Y++ME C GG+L L+ ++T + + A + EA + +H
Sbjct: 432 HSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLH 491
Query: 525 AKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYM 704
+KGI++RDLKP+N++L H K+ DFGFA+ + G T CG+P Y+
Sbjct: 492 SKGIIYRDLKPENLILDHRGYA-----------KLVDFGFAKKIGFGKKTWTFCGTPEYV 540
Query: 705 APEVIMS 725
APE+I++
Sbjct: 541 APEIILN 547
>AL731537-2|CAI17114.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 97.5 bits (232), Expect = 4e-20
Identities = 55/187 (29%), Positives = 101/187 (54%), Gaps = 1/187 (0%)
Frame = +3
Query: 168 EFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQ 347
+F D +G G F V + + S++ A+K++ K+ I + + I+ +++
Sbjct: 347 DFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQ--QEHIRSEKQIMQGA 404
Query: 348 HKN-LVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIH 524
H + +V ++ Y+Y++ME C GG+L L+ ++T + + A + EA + +H
Sbjct: 405 HSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLH 464
Query: 525 AKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYM 704
+KGI++RDLKP+N++L H K+ DFGFA+ + G T CG+P Y+
Sbjct: 465 SKGIIYRDLKPENLILDHRGYA-----------KLVDFGFAKKIGFGKKTWTFCGTPEYV 513
Query: 705 APEVIMS 725
APE+I++
Sbjct: 514 APEIILN 520
>AL391378-2|CAI39626.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 97.5 bits (232), Expect = 4e-20
Identities = 55/187 (29%), Positives = 101/187 (54%), Gaps = 1/187 (0%)
Frame = +3
Query: 168 EFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQ 347
+F D +G G F V + + S++ A+K++ K+ I + + I+ +++
Sbjct: 374 DFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQ--QEHIRSEKQIMQGA 431
Query: 348 HKN-LVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIH 524
H + +V ++ Y+Y++ME C GG+L L+ ++T + + A + EA + +H
Sbjct: 432 HSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLH 491
Query: 525 AKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYM 704
+KGI++RDLKP+N++L H K+ DFGFA+ + G T CG+P Y+
Sbjct: 492 SKGIIYRDLKPENLILDHRGYA-----------KLVDFGFAKKIGFGKKTWTFCGTPEYV 540
Query: 705 APEVIMS 725
APE+I++
Sbjct: 541 APEIILN 547
>AL391378-1|CAI39625.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 97.5 bits (232), Expect = 4e-20
Identities = 55/187 (29%), Positives = 101/187 (54%), Gaps = 1/187 (0%)
Frame = +3
Query: 168 EFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQ 347
+F D +G G F V + + S++ A+K++ K+ I + + I+ +++
Sbjct: 347 DFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQ--QEHIRSEKQIMQGA 404
Query: 348 HKN-LVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIH 524
H + +V ++ Y+Y++ME C GG+L L+ ++T + + A + EA + +H
Sbjct: 405 HSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLH 464
Query: 525 AKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYM 704
+KGI++RDLKP+N++L H K+ DFGFA+ + G T CG+P Y+
Sbjct: 465 SKGIIYRDLKPENLILDHRGYA-----------KLVDFGFAKKIGFGKKTWTFCGTPEYV 513
Query: 705 APEVIMS 725
APE+I++
Sbjct: 514 APEIILN 520
>AL157399-2|CAI41305.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 97.5 bits (232), Expect = 4e-20
Identities = 55/187 (29%), Positives = 101/187 (54%), Gaps = 1/187 (0%)
Frame = +3
Query: 168 EFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQ 347
+F D +G G F V + + S++ A+K++ K+ I + + I+ +++
Sbjct: 374 DFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQ--QEHIRSEKQIMQGA 431
Query: 348 HKN-LVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIH 524
H + +V ++ Y+Y++ME C GG+L L+ ++T + + A + EA + +H
Sbjct: 432 HSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLH 491
Query: 525 AKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYM 704
+KGI++RDLKP+N++L H K+ DFGFA+ + G T CG+P Y+
Sbjct: 492 SKGIIYRDLKPENLILDHRGYA-----------KLVDFGFAKKIGFGKKTWTFCGTPEYV 540
Query: 705 APEVIMS 725
APE+I++
Sbjct: 541 APEIILN 547
>AL157399-1|CAI41304.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 97.5 bits (232), Expect = 4e-20
Identities = 55/187 (29%), Positives = 101/187 (54%), Gaps = 1/187 (0%)
Frame = +3
Query: 168 EFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQ 347
+F D +G G F V + + S++ A+K++ K+ I + + I+ +++
Sbjct: 347 DFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQ--QEHIRSEKQIMQGA 404
Query: 348 HKN-LVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIH 524
H + +V ++ Y+Y++ME C GG+L L+ ++T + + A + EA + +H
Sbjct: 405 HSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLH 464
Query: 525 AKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYM 704
+KGI++RDLKP+N++L H K+ DFGFA+ + G T CG+P Y+
Sbjct: 465 SKGIIYRDLKPENLILDHRGYA-----------KLVDFGFAKKIGFGKKTWTFCGTPEYV 513
Query: 705 APEVIMS 725
APE+I++
Sbjct: 514 APEIILN 520
>AK131534-1|BAD18671.1| 766|Homo sapiens protein ( Homo sapiens
cDNA FLJ16763 fis, clone BRAMY3018357, weakly similar
to SNF1-related protein kinase KIN10 (EC 2.7.1.-). ).
Length = 766
Score = 97.5 bits (232), Expect = 4e-20
Identities = 52/158 (32%), Positives = 88/158 (55%)
Frame = +3
Query: 246 QSVAVKVVTKKGIQKASEILVKEIKILRELTALQHKNLVAMHDCMDSPAYVYVVMEYCNG 425
Q VA+K+V ++ + ++ +L+K + + L ++H +++ +HD ++ Y+Y+V+E+ +G
Sbjct: 89 QKVAIKIVNREKLSES--VLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSG 146
Query: 426 GDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIVHRDLKPQNILLTHSILPPRTPH 605
G+L DYL L+ + F Q+ A+ H+ I HRDLKP+N+LL
Sbjct: 147 GELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEK-------- 198
Query: 606 PSDITLKIADFGFARFLEEGNMAVTLCGSPMYMAPEVI 719
++IADFG A ++ T CGSP Y PEVI
Sbjct: 199 ---NNIRIADFGMASLQVGDSLLETSCGSPHYACPEVI 233
>AB006972-1|BAB69958.1| 970|Homo sapiens Sak protein.
Length = 970
Score = 97.5 bits (232), Expect = 4e-20
Identities = 60/187 (32%), Positives = 106/187 (56%), Gaps = 4/187 (2%)
Frame = +3
Query: 168 EFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI--LVKEIKILRELTA 341
+F +++G G+FA VY+ + + VA+K++ KK + KA + + E+KI +L
Sbjct: 11 DFKVGNLLGKGSFAGVYRAESIHSGLE-VAIKMIDKKAMYKAGMVQRVQNEVKIHCQL-- 67
Query: 342 LQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTN-RLLSETTIQLFLAQLAEAMSA 518
+H +++ +++ + YVY+V+E C+ G++ YL+ + SE + F+ Q+ M
Sbjct: 68 -KHPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLY 126
Query: 519 IHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLE-EGNMAVTLCGSP 695
+H+ GI+HRDL N+LLT ++ +KIADFG A L+ TLCG+P
Sbjct: 127 LHSHGILHRDLTLSNLLLTR-----------NMNIKIADFGLATQLKMPHEKHYTLCGTP 175
Query: 696 MYMAPEV 716
Y++PE+
Sbjct: 176 NYISPEI 182
>Z98752-7|CAI42315.1| 366|Homo sapiens serum/glucocorticoid
regulated kinase 2 protein.
Length = 366
Score = 97.1 bits (231), Expect = 6e-20
Identities = 66/191 (34%), Positives = 102/191 (53%), Gaps = 2/191 (1%)
Frame = +3
Query: 153 QVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI-LVKEIKILR 329
Q D++F K +IG G + V KRK+ AVKV+ KK I K E ++ E +L
Sbjct: 31 QPTDFDFLK--VIGKGNYGKVLLA-KRKSDGAFYAVKVLQKKSILKKKESHIMAERSVL- 86
Query: 330 ELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEA 509
L ++H LV + +P +Y V++Y NGG+L +LQ R E + + A++A A
Sbjct: 87 -LKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASA 145
Query: 510 MSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARF-LEEGNMAVTLC 686
+ +H+ I++RDLKP+NILL H + + DFG + +E + T C
Sbjct: 146 IGYLHSLNIIYRDLKPENILLDCQ------GH-----VVLTDFGLCKEGVEPEDTTSTFC 194
Query: 687 GSPMYMAPEVI 719
G+P Y+APEV+
Sbjct: 195 GTPEYLAPEVL 205
>D43636-1|BAA07744.2| 766|Homo sapiens KIAA0096 protein.
Length = 766
Score = 96.3 bits (229), Expect = 1e-19
Identities = 59/190 (31%), Positives = 103/190 (54%), Gaps = 2/190 (1%)
Frame = +3
Query: 159 GDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQK-ASEILVKEIKILREL 335
G Y+ K +G G FA+V K + + VAVKV+ K + A+ L +E++ ++
Sbjct: 15 GLYDLDKT--LGRGHFAVV-KLARHVFTGEKVAVKVIDKTKLDTLATGHLFQEVRCMK-- 69
Query: 336 TALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRL-LSETTIQLFLAQLAEAM 512
+QH N+V +++ +D+ +Y+++E +GGD+ DY+ + L+E + + AQ+ A+
Sbjct: 70 -LVQHPNIVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAI 128
Query: 513 SAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGS 692
S H +VHRDLKP+N++ +K+ DFGF+ + G T CGS
Sbjct: 129 SYCHKLHVVHRDLKPENVVF----------FEKQGLVKLTDFGFSNKFQPGKKLTTSCGS 178
Query: 693 PMYMAPEVIM 722
Y APE+++
Sbjct: 179 LAYSAPEILL 188
>CR536566-1|CAG38803.1| 745|Homo sapiens RPS6KA6 protein.
Length = 745
Score = 96.3 bits (229), Expect = 1e-19
Identities = 57/187 (30%), Positives = 100/187 (53%), Gaps = 3/187 (1%)
Frame = +3
Query: 168 EFTKQDIIGHGAFAMVYKGRKRKNPS--QSVAVKVVTKKGIQKASEILVKEIKILRELTA 341
+F ++G G+F V+ RK+ P Q A+KV+ K ++ + K + + L
Sbjct: 72 QFELLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASLKVRGRVRTKMERDI--LVE 129
Query: 342 LQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAI 521
+ H +V +H + +Y+++++ GGD+ L L +E ++ +LA+LA A+ +
Sbjct: 130 VNHPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLAELALALDHL 189
Query: 522 HAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFAR-FLEEGNMAVTLCGSPM 698
H GIV+RDLKP+NILL H +K+ DFG ++ +++ A + CG+
Sbjct: 190 HQLGIVYRDLKPENILL------DEIGH-----IKLTDFGLSKESVDQEKKAYSFCGTVE 238
Query: 699 YMAPEVI 719
YMAPEV+
Sbjct: 239 YMAPEVV 245
Score = 88.6 bits (210), Expect = 2e-17
Identities = 63/191 (32%), Positives = 98/191 (51%), Gaps = 1/191 (0%)
Frame = +3
Query: 153 QVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRE 332
Q G+ K+DI G G+++ V K + AVK++ K + SE EI+IL
Sbjct: 421 QFGEVYELKEDI-GVGSYS-VCKRCIHATTNMEFAVKIIDKSK-RDPSE----EIEILMR 473
Query: 333 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 512
QH N++ + D D YVY+V + GG+L D + + SE L +++ +
Sbjct: 474 YG--QHPNIITLKDVFDDGRYVYLVTDLMKGGELLDRILKQKCFSEREASDILYVISKTV 531
Query: 513 SAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLE-EGNMAVTLCG 689
+H +G+VHRDLKP NIL S +++I DFGFA+ L E + +T C
Sbjct: 532 DYLHCQGVVHRDLKPSNILYMDE-------SASADSIRICDFGFAKQLRGENGLLLTPCY 584
Query: 690 SPMYMAPEVIM 722
+ ++APEV+M
Sbjct: 585 TANFVAPEVLM 595
>BC071567-1|AAH71567.1| 765|Homo sapiens SNRK protein protein.
Length = 765
Score = 96.3 bits (229), Expect = 1e-19
Identities = 59/190 (31%), Positives = 103/190 (54%), Gaps = 2/190 (1%)
Frame = +3
Query: 159 GDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQK-ASEILVKEIKILREL 335
G Y+ K +G G FA+V K + + VAVKV+ K + A+ L +E++ ++
Sbjct: 14 GLYDLDKT--LGRGHFAVV-KLARHVFTGEKVAVKVIDKTKLDTLATGHLFQEVRCMK-- 68
Query: 336 TALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRL-LSETTIQLFLAQLAEAM 512
+QH N+V +++ +D+ +Y+++E +GGD+ DY+ + L+E + + AQ+ A+
Sbjct: 69 -LVQHPNIVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAI 127
Query: 513 SAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGS 692
S H +VHRDLKP+N++ +K+ DFGF+ + G T CGS
Sbjct: 128 SYCHKLHVVHRDLKPENVVF----------FEKQGLVKLTDFGFSNKFQPGKKLTTSCGS 177
Query: 693 PMYMAPEVIM 722
Y APE+++
Sbjct: 178 LAYSAPEILL 187
>AL389887-1|CAC16111.2| 745|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 6 protein.
Length = 745
Score = 96.3 bits (229), Expect = 1e-19
Identities = 57/187 (30%), Positives = 100/187 (53%), Gaps = 3/187 (1%)
Frame = +3
Query: 168 EFTKQDIIGHGAFAMVYKGRKRKNPS--QSVAVKVVTKKGIQKASEILVKEIKILRELTA 341
+F ++G G+F V+ RK+ P Q A+KV+ K ++ + K + + L
Sbjct: 72 QFELLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASLKVRDRVRTKMERDI--LVE 129
Query: 342 LQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAI 521
+ H +V +H + +Y+++++ GGD+ L L +E ++ +LA+LA A+ +
Sbjct: 130 VNHPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLAELALALDHL 189
Query: 522 HAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFAR-FLEEGNMAVTLCGSPM 698
H GIV+RDLKP+NILL H +K+ DFG ++ +++ A + CG+
Sbjct: 190 HQLGIVYRDLKPENILL------DEIGH-----IKLTDFGLSKESVDQEKKAYSFCGTVE 238
Query: 699 YMAPEVI 719
YMAPEV+
Sbjct: 239 YMAPEVV 245
Score = 88.6 bits (210), Expect = 2e-17
Identities = 63/191 (32%), Positives = 98/191 (51%), Gaps = 1/191 (0%)
Frame = +3
Query: 153 QVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRE 332
Q G+ K+DI G G+++ V K + AVK++ K + SE EI+IL
Sbjct: 421 QFGEVYELKEDI-GVGSYS-VCKRCIHATTNMEFAVKIIDKSK-RDPSE----EIEILMR 473
Query: 333 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 512
QH N++ + D D YVY+V + GG+L D + + SE L +++ +
Sbjct: 474 YG--QHPNIITLKDVFDDGRYVYLVTDLMKGGELLDRILKQKCFSEREASDILYVISKTV 531
Query: 513 SAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLE-EGNMAVTLCG 689
+H +G+VHRDLKP NIL S +++I DFGFA+ L E + +T C
Sbjct: 532 DYLHCQGVVHRDLKPSNILYMDE-------SASADSIRICDFGFAKQLRGENGLLLTPCY 584
Query: 690 SPMYMAPEVIM 722
+ ++APEV+M
Sbjct: 585 TANFVAPEVLM 595
>AL354653-1|CAD13486.2| 745|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 6 protein.
Length = 745
Score = 96.3 bits (229), Expect = 1e-19
Identities = 57/187 (30%), Positives = 100/187 (53%), Gaps = 3/187 (1%)
Frame = +3
Query: 168 EFTKQDIIGHGAFAMVYKGRKRKNPS--QSVAVKVVTKKGIQKASEILVKEIKILRELTA 341
+F ++G G+F V+ RK+ P Q A+KV+ K ++ + K + + L
Sbjct: 72 QFELLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASLKVRDRVRTKMERDI--LVE 129
Query: 342 LQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAI 521
+ H +V +H + +Y+++++ GGD+ L L +E ++ +LA+LA A+ +
Sbjct: 130 VNHPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLAELALALDHL 189
Query: 522 HAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFAR-FLEEGNMAVTLCGSPM 698
H GIV+RDLKP+NILL H +K+ DFG ++ +++ A + CG+
Sbjct: 190 HQLGIVYRDLKPENILL------DEIGH-----IKLTDFGLSKESVDQEKKAYSFCGTVE 238
Query: 699 YMAPEVI 719
YMAPEV+
Sbjct: 239 YMAPEVV 245
Score = 88.6 bits (210), Expect = 2e-17
Identities = 63/191 (32%), Positives = 98/191 (51%), Gaps = 1/191 (0%)
Frame = +3
Query: 153 QVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRE 332
Q G+ K+DI G G+++ V K + AVK++ K + SE EI+IL
Sbjct: 421 QFGEVYELKEDI-GVGSYS-VCKRCIHATTNMEFAVKIIDKSK-RDPSE----EIEILMR 473
Query: 333 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 512
QH N++ + D D YVY+V + GG+L D + + SE L +++ +
Sbjct: 474 YG--QHPNIITLKDVFDDGRYVYLVTDLMKGGELLDRILKQKCFSEREASDILYVISKTV 531
Query: 513 SAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLE-EGNMAVTLCG 689
+H +G+VHRDLKP NIL S +++I DFGFA+ L E + +T C
Sbjct: 532 DYLHCQGVVHRDLKPSNILYMDE-------SASADSIRICDFGFAKQLRGENGLLLTPCY 584
Query: 690 SPMYMAPEVIM 722
+ ++APEV+M
Sbjct: 585 TANFVAPEVLM 595
>AK000231-1|BAA91023.1| 244|Homo sapiens protein ( Homo sapiens
cDNA FLJ20224 fis, clone COLF5039. ).
Length = 244
Score = 96.3 bits (229), Expect = 1e-19
Identities = 59/190 (31%), Positives = 103/190 (54%), Gaps = 2/190 (1%)
Frame = +3
Query: 159 GDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQK-ASEILVKEIKILREL 335
G Y+ K +G G FA+V K + + VAVKV+ K + A+ L +E++ ++
Sbjct: 14 GLYDLDKT--LGRGHFAVV-KLARHVFTGEKVAVKVIDKTKLDTLATGHLFQEVRCMK-- 68
Query: 336 TALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRL-LSETTIQLFLAQLAEAM 512
+QH N+V +++ +D+ +Y+++E +GGD+ DY+ + L+E + + AQ+ A+
Sbjct: 69 -LVQHPNIVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAI 127
Query: 513 SAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGS 692
S H +VHRDLKP+N++ +K+ DFGF+ + G T CGS
Sbjct: 128 SYCHKLHVVHRDLKPENVVF----------FEKQGLVKLTDFGFSNKFQPGKKLTTSCGS 177
Query: 693 PMYMAPEVIM 722
Y APE+++
Sbjct: 178 LAYSAPEILL 187
>AF184965-1|AAF13190.1| 745|Homo sapiens ribosomal S6 kinase
protein.
Length = 745
Score = 96.3 bits (229), Expect = 1e-19
Identities = 57/187 (30%), Positives = 100/187 (53%), Gaps = 3/187 (1%)
Frame = +3
Query: 168 EFTKQDIIGHGAFAMVYKGRKRKNPS--QSVAVKVVTKKGIQKASEILVKEIKILRELTA 341
+F ++G G+F V+ RK+ P Q A+KV+ K ++ + K + + L
Sbjct: 72 QFELLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASLKVRDRVRTKMERDI--LVE 129
Query: 342 LQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAI 521
+ H +V +H + +Y+++++ GGD+ L L +E ++ +LA+LA A+ +
Sbjct: 130 VNHPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLAELALALDHL 189
Query: 522 HAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFAR-FLEEGNMAVTLCGSPM 698
H GIV+RDLKP+NILL H +K+ DFG ++ +++ A + CG+
Sbjct: 190 HQLGIVYRDLKPENILL------DEIGH-----IKLTDFGLSKESVDQEKKAYSFCGTVE 238
Query: 699 YMAPEVI 719
YMAPEV+
Sbjct: 239 YMAPEVV 245
Score = 88.6 bits (210), Expect = 2e-17
Identities = 63/191 (32%), Positives = 98/191 (51%), Gaps = 1/191 (0%)
Frame = +3
Query: 153 QVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRE 332
Q G+ K+DI G G+++ V K + AVK++ K + SE EI+IL
Sbjct: 421 QFGEVYELKEDI-GVGSYS-VCKRCIHATTNMEFAVKIIDKSK-RDPSE----EIEILMR 473
Query: 333 LTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAM 512
QH N++ + D D YVY+V + GG+L D + + SE L +++ +
Sbjct: 474 YG--QHPNIITLKDVFDDGRYVYLVTDLMKGGELLDRILKQKCFSEREASDILYVISKTV 531
Query: 513 SAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLE-EGNMAVTLCG 689
+H +G+VHRDLKP NIL S +++I DFGFA+ L E + +T C
Sbjct: 532 DYLHCQGVVHRDLKPSNILYMDE-------SASADSIRICDFGFAKQLRGENGLLLTPCY 584
Query: 690 SPMYMAPEVIM 722
+ ++APEV+M
Sbjct: 585 TANFVAPEVLM 595
>Z98752-8|CAC18509.1| 367|Homo sapiens serum/glucocorticoid
regulated kinase 2 protein.
Length = 367
Score = 95.9 bits (228), Expect = 1e-19
Identities = 66/192 (34%), Positives = 102/192 (53%), Gaps = 3/192 (1%)
Frame = +3
Query: 153 QVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI--LVKEIKIL 326
Q D++F K +IG G + V KRK+ AVKV+ KK I K E ++ E +L
Sbjct: 31 QPTDFDFLK--VIGKGNYGKVLLA-KRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVL 87
Query: 327 RELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAE 506
L ++H LV + +P +Y V++Y NGG+L +LQ R E + + A++A
Sbjct: 88 --LKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVAS 145
Query: 507 AMSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARF-LEEGNMAVTL 683
A+ +H+ I++RDLKP+NILL H + + DFG + +E + T
Sbjct: 146 AIGYLHSLNIIYRDLKPENILLDCQ------GH-----VVLTDFGLCKEGVEPEDTTSTF 194
Query: 684 CGSPMYMAPEVI 719
CG+P Y+APEV+
Sbjct: 195 CGTPEYLAPEVL 206
>Z98752-5|CAI42312.1| 427|Homo sapiens serum/glucocorticoid
regulated kinase 2 protein.
Length = 427
Score = 95.9 bits (228), Expect = 1e-19
Identities = 66/192 (34%), Positives = 102/192 (53%), Gaps = 3/192 (1%)
Frame = +3
Query: 153 QVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI--LVKEIKIL 326
Q D++F K +IG G + V KRK+ AVKV+ KK I K E ++ E +L
Sbjct: 91 QPTDFDFLK--VIGKGNYGKVLLA-KRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVL 147
Query: 327 RELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAE 506
L ++H LV + +P +Y V++Y NGG+L +LQ R E + + A++A
Sbjct: 148 --LKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVAS 205
Query: 507 AMSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARF-LEEGNMAVTL 683
A+ +H+ I++RDLKP+NILL H + + DFG + +E + T
Sbjct: 206 AIGYLHSLNIIYRDLKPENILLDCQ------GH-----VVLTDFGLCKEGVEPEDTTSTF 254
Query: 684 CGSPMYMAPEVI 719
CG+P Y+APEV+
Sbjct: 255 CGTPEYLAPEVL 266
>Z98049-1|CAI20579.1| 733|Homo sapiens ribosomal protein S6 kinase,
90kDa, polypeptide 2 protein.
Length = 733
Score = 95.9 bits (228), Expect = 1e-19
Identities = 68/186 (36%), Positives = 100/186 (53%), Gaps = 1/186 (0%)
Frame = +3
Query: 165 YEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTAL 344
YE K+DI G G+++ V K K AVK++ K + SE EI+IL L
Sbjct: 415 YEI-KEDI-GVGSYS-VCKRCVHKATDTEYAVKIIDKSK-RDPSE----EIEIL--LRYG 464
Query: 345 QHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIH 524
QH N++ + D D +VY+VME GG+L D + R SE L + + M +H
Sbjct: 465 QHPNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLH 524
Query: 525 AKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGN-MAVTLCGSPMY 701
++G+VHRDLKP NIL R S ++++ DFGFA+ L GN + +T C + +
Sbjct: 525 SQGVVHRDLKPSNILY-------RDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANF 577
Query: 702 MAPEVI 719
+APEV+
Sbjct: 578 VAPEVL 583
Score = 93.1 bits (221), Expect = 9e-19
Identities = 59/188 (31%), Positives = 101/188 (53%), Gaps = 4/188 (2%)
Frame = +3
Query: 168 EFTKQDIIGHGAFAMVYKGRKRK--NPSQSVAVKVVTKKGIQKASEILVK-EIKILRELT 338
+F ++G G++ V+ RK K + Q A+KV+ K ++ + K E IL E+
Sbjct: 58 QFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKMERDILAEVN 117
Query: 339 ALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSA 518
H +V +H + +Y+++++ GGDL L + +E ++ +LA+LA A+
Sbjct: 118 ---HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDH 174
Query: 519 IHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFAR-FLEEGNMAVTLCGSP 695
+H+ GI++RDLKP+NILL H +KI DFG ++ ++ A + CG+
Sbjct: 175 LHSLGIIYRDLKPENILLDEE------GH-----IKITDFGLSKEAIDHDKRAYSFCGTI 223
Query: 696 MYMAPEVI 719
YMAPEV+
Sbjct: 224 EYMAPEVV 231
>X85106-1|CAA59427.1| 733|Homo sapiens ribosomal S6 kinase protein.
Length = 733
Score = 95.9 bits (228), Expect = 1e-19
Identities = 68/186 (36%), Positives = 100/186 (53%), Gaps = 1/186 (0%)
Frame = +3
Query: 165 YEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTAL 344
YE K+DI G G+++ V K K AVK++ K + SE EI+IL L
Sbjct: 415 YEI-KEDI-GVGSYS-VCKRCVHKATDTEYAVKIIDKSK-RDPSE----EIEIL--LRYG 464
Query: 345 QHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIH 524
QH N++ + D D +VY+VME GG+L D + R SE L + + M +H
Sbjct: 465 QHPNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLH 524
Query: 525 AKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGN-MAVTLCGSPMY 701
++G+VHRDLKP NIL R S ++++ DFGFA+ L GN + +T C + +
Sbjct: 525 SQGVVHRDLKPSNILY-------RDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANF 577
Query: 702 MAPEVI 719
+APEV+
Sbjct: 578 VAPEVL 583
Score = 93.1 bits (221), Expect = 9e-19
Identities = 59/188 (31%), Positives = 101/188 (53%), Gaps = 4/188 (2%)
Frame = +3
Query: 168 EFTKQDIIGHGAFAMVYKGRKRK--NPSQSVAVKVVTKKGIQKASEILVK-EIKILRELT 338
+F ++G G++ V+ RK K + Q A+KV+ K ++ + K E IL E+
Sbjct: 58 QFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKMERDILAEVN 117
Query: 339 ALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSA 518
H +V +H + +Y+++++ GGDL L + +E ++ +LA+LA A+
Sbjct: 118 ---HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDH 174
Query: 519 IHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFAR-FLEEGNMAVTLCGSP 695
+H+ GI++RDLKP+NILL H +KI DFG ++ ++ A + CG+
Sbjct: 175 LHSLGIIYRDLKPENILLDEE------GH-----IKITDFGLSKEAIDHDKRAYSFCGTI 223
Query: 696 MYMAPEVI 719
YMAPEV+
Sbjct: 224 EYMAPEVV 231
>BT020098-1|AAV38901.1| 367|Homo sapiens serum/glucocorticoid
regulated kinase 2 protein.
Length = 367
Score = 95.9 bits (228), Expect = 1e-19
Identities = 66/192 (34%), Positives = 102/192 (53%), Gaps = 3/192 (1%)
Frame = +3
Query: 153 QVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI--LVKEIKIL 326
Q D++F K +IG G + V KRK+ AVKV+ KK I K E ++ E +L
Sbjct: 31 QPTDFDFLK--VIGKGNYGKVLLA-KRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVL 87
Query: 327 RELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAE 506
L ++H LV + +P +Y V++Y NGG+L +LQ R E + + A++A
Sbjct: 88 --LKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVAS 145
Query: 507 AMSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARF-LEEGNMAVTL 683
A+ +H+ I++RDLKP+NILL H + + DFG + +E + T
Sbjct: 146 AIDYLHSLNIIYRDLKPENILLDCQ------GH-----VVLTDFGLCKEGVEPEDTTSTF 194
Query: 684 CGSPMYMAPEVI 719
CG+P Y+APEV+
Sbjct: 195 CGTPEYLAPEVL 206
>BC065511-1|AAH65511.1| 367|Homo sapiens SGK2 protein protein.
Length = 367
Score = 95.9 bits (228), Expect = 1e-19
Identities = 66/192 (34%), Positives = 102/192 (53%), Gaps = 3/192 (1%)
Frame = +3
Query: 153 QVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI--LVKEIKIL 326
Q D++F K +IG G + V KRK+ AVKV+ KK I K E ++ E +L
Sbjct: 31 QPTDFDFLK--VIGKGNYGKVLLA-KRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVL 87
Query: 327 RELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAE 506
L ++H LV + +P +Y V++Y NGG+L +LQ R E + + A++A
Sbjct: 88 --LKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVAS 145
Query: 507 AMSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARF-LEEGNMAVTL 683
A+ +H+ I++RDLKP+NILL H + + DFG + +E + T
Sbjct: 146 AIGYLHSLNIIYRDLKPENILLDCQ------GH-----VVLTDFGLCKEGVEPEDTTSTF 194
Query: 684 CGSPMYMAPEVI 719
CG+P Y+APEV+
Sbjct: 195 CGTPEYLAPEVL 206
>BC014037-1|AAH14037.3| 367|Homo sapiens serum/glucocorticoid
regulated kinase 2 protein.
Length = 367
Score = 95.9 bits (228), Expect = 1e-19
Identities = 66/192 (34%), Positives = 102/192 (53%), Gaps = 3/192 (1%)
Frame = +3
Query: 153 QVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI--LVKEIKIL 326
Q D++F K +IG G + V KRK+ AVKV+ KK I K E ++ E +L
Sbjct: 31 QPTDFDFLK--VIGKGNYGKVLLA-KRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVL 87
Query: 327 RELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAE 506
L ++H LV + +P +Y V++Y NGG+L +LQ R E + + A++A
Sbjct: 88 --LKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVAS 145
Query: 507 AMSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARF-LEEGNMAVTL 683
A+ +H+ I++RDLKP+NILL H + + DFG + +E + T
Sbjct: 146 AIGYLHSLNIIYRDLKPENILLDCQ------GH-----VVLTDFGLCKEGVEPEDTTSTF 194
Query: 684 CGSPMYMAPEVI 719
CG+P Y+APEV+
Sbjct: 195 CGTPEYLAPEVL 206
>BC002363-1|AAH02363.1| 733|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 2 protein.
Length = 733
Score = 95.9 bits (228), Expect = 1e-19
Identities = 68/186 (36%), Positives = 100/186 (53%), Gaps = 1/186 (0%)
Frame = +3
Query: 165 YEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTAL 344
YE K+DI G G+++ V K K AVK++ K + SE EI+IL L
Sbjct: 415 YEI-KEDI-GVGSYS-VCKRCVHKATDTEYAVKIIDKSK-RDPSE----EIEIL--LRYG 464
Query: 345 QHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIH 524
QH N++ + D D +VY+VME GG+L D + R SE L + + M +H
Sbjct: 465 QHPNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLH 524
Query: 525 AKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGN-MAVTLCGSPMY 701
++G+VHRDLKP NIL R S ++++ DFGFA+ L GN + +T C + +
Sbjct: 525 SQGVVHRDLKPSNILY-------RDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANF 577
Query: 702 MAPEVI 719
+APEV+
Sbjct: 578 VAPEVL 583
Score = 93.1 bits (221), Expect = 9e-19
Identities = 59/188 (31%), Positives = 101/188 (53%), Gaps = 4/188 (2%)
Frame = +3
Query: 168 EFTKQDIIGHGAFAMVYKGRKRK--NPSQSVAVKVVTKKGIQKASEILVK-EIKILRELT 338
+F ++G G++ V+ RK K + Q A+KV+ K ++ + K E IL E+
Sbjct: 58 QFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKMERDILAEVN 117
Query: 339 ALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSA 518
H +V +H + +Y+++++ GGDL L + +E ++ +LA+LA A+
Sbjct: 118 ---HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDH 174
Query: 519 IHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFAR-FLEEGNMAVTLCGSP 695
+H+ GI++RDLKP+NILL H +KI DFG ++ ++ A + CG+
Sbjct: 175 LHSLGIIYRDLKPENILLDEE------GH-----IKITDFGLSKEAIDHDKRAYSFCGTI 223
Query: 696 MYMAPEVI 719
YMAPEV+
Sbjct: 224 EYMAPEVV 231
>AY987010-1|AAX88805.1| 393|Homo sapiens serum/glucocorticoid
regulated kinase 2 protein.
Length = 393
Score = 95.9 bits (228), Expect = 1e-19
Identities = 66/192 (34%), Positives = 102/192 (53%), Gaps = 3/192 (1%)
Frame = +3
Query: 153 QVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI--LVKEIKIL 326
Q D++F K +IG G + V KRK+ AVKV+ KK I K E ++ E +L
Sbjct: 57 QPTDFDFLK--VIGKGNYGKVLLA-KRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVL 113
Query: 327 RELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAE 506
L ++H LV + +P +Y V++Y NGG+L +LQ R E + + A++A
Sbjct: 114 --LKNVRHPFLVGLRYSFQTPEELYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVAS 171
Query: 507 AMSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARF-LEEGNMAVTL 683
A+ +H+ I++RDLKP+NILL H + + DFG + +E + T
Sbjct: 172 AIGYLHSLNIIYRDLKPENILLDCQ------GH-----VVLTDFGLCKEGVEPEDTTSTF 220
Query: 684 CGSPMYMAPEVI 719
CG+P Y+APEV+
Sbjct: 221 CGTPEYLAPEVL 232
>AL022069-2|CAI19651.1| 733|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 2 protein.
Length = 733
Score = 95.9 bits (228), Expect = 1e-19
Identities = 68/186 (36%), Positives = 100/186 (53%), Gaps = 1/186 (0%)
Frame = +3
Query: 165 YEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTAL 344
YE K+DI G G+++ V K K AVK++ K + SE EI+IL L
Sbjct: 415 YEI-KEDI-GVGSYS-VCKRCVHKATDTEYAVKIIDKSK-RDPSE----EIEIL--LRYG 464
Query: 345 QHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIH 524
QH N++ + D D +VY+VME GG+L D + R SE L + + M +H
Sbjct: 465 QHPNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLH 524
Query: 525 AKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGN-MAVTLCGSPMY 701
++G+VHRDLKP NIL R S ++++ DFGFA+ L GN + +T C + +
Sbjct: 525 SQGVVHRDLKPSNILY-------RDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANF 577
Query: 702 MAPEVI 719
+APEV+
Sbjct: 578 VAPEVL 583
Score = 93.1 bits (221), Expect = 9e-19
Identities = 59/188 (31%), Positives = 101/188 (53%), Gaps = 4/188 (2%)
Frame = +3
Query: 168 EFTKQDIIGHGAFAMVYKGRKRK--NPSQSVAVKVVTKKGIQKASEILVK-EIKILRELT 338
+F ++G G++ V+ RK K + Q A+KV+ K ++ + K E IL E+
Sbjct: 58 QFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKMERDILAEVN 117
Query: 339 ALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSA 518
H +V +H + +Y+++++ GGDL L + +E ++ +LA+LA A+
Sbjct: 118 ---HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDH 174
Query: 519 IHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFAR-FLEEGNMAVTLCGSP 695
+H+ GI++RDLKP+NILL H +KI DFG ++ ++ A + CG+
Sbjct: 175 LHSLGIIYRDLKPENILLDEE------GH-----IKITDFGLSKEAIDHDKRAYSFCGTI 223
Query: 696 MYMAPEVI 719
YMAPEV+
Sbjct: 224 EYMAPEVV 231
>AF186470-1|AAG17012.1| 427|Homo sapiens protein kinase protein.
Length = 427
Score = 95.9 bits (228), Expect = 1e-19
Identities = 66/192 (34%), Positives = 102/192 (53%), Gaps = 3/192 (1%)
Frame = +3
Query: 153 QVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI--LVKEIKIL 326
Q D++F K +IG G + V KRK+ AVKV+ KK I K E ++ E +L
Sbjct: 91 QPTDFDFLK--VIGKGNYGKVLLA-KRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVL 147
Query: 327 RELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAE 506
L ++H LV + +P +Y V++Y NGG+L +LQ R E + + A++A
Sbjct: 148 --LKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVAS 205
Query: 507 AMSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARF-LEEGNMAVTL 683
A+ +H+ I++RDLKP+NILL H + + DFG + +E + T
Sbjct: 206 AIGYLHSLNIIYRDLKPENILLDCQ------GH-----VVLTDFGLCKEGVEPEDTTSTF 254
Query: 684 CGSPMYMAPEVI 719
CG+P Y+APEV+
Sbjct: 255 CGTPEYLAPEVL 266
>AF169034-1|AAF12757.2| 367|Homo sapiens protein kinase protein.
Length = 367
Score = 95.9 bits (228), Expect = 1e-19
Identities = 66/192 (34%), Positives = 102/192 (53%), Gaps = 3/192 (1%)
Frame = +3
Query: 153 QVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI--LVKEIKIL 326
Q D++F K +IG G + V KRK+ AVKV+ KK I K E ++ E +L
Sbjct: 31 QPTDFDFLK--VIGKGNYGKVLLA-KRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVL 87
Query: 327 RELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAE 506
L ++H LV + +P +Y V++Y NGG+L +LQ R E + + A++A
Sbjct: 88 --LKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVAS 145
Query: 507 AMSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARF-LEEGNMAVTL 683
A+ +H+ I++RDLKP+NILL H + + DFG + +E + T
Sbjct: 146 AIGYLHSLNIIYRDLKPENILLDCQ------GH-----VVLTDFGLCKEGVEPEDTTSTF 194
Query: 684 CGSPMYMAPEVI 719
CG+P Y+APEV+
Sbjct: 195 CGTPEYLAPEVL 206
>AB209116-1|BAD92353.1| 806|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 2 isoform b variant protein.
Length = 806
Score = 95.9 bits (228), Expect = 1e-19
Identities = 68/186 (36%), Positives = 100/186 (53%), Gaps = 1/186 (0%)
Frame = +3
Query: 165 YEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTAL 344
YE K+DI G G+++ V K K AVK++ K + SE EI+IL L
Sbjct: 488 YEI-KEDI-GVGSYS-VCKRCVHKATDTEYAVKIIDKSK-RDPSE----EIEIL--LRYG 537
Query: 345 QHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIH 524
QH N++ + D D +VY+VME GG+L D + R SE L + + M +H
Sbjct: 538 QHPNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLH 597
Query: 525 AKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGN-MAVTLCGSPMY 701
++G+VHRDLKP NIL R S ++++ DFGFA+ L GN + +T C + +
Sbjct: 598 SQGVVHRDLKPSNILY-------RDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANF 650
Query: 702 MAPEVI 719
+APEV+
Sbjct: 651 VAPEVL 656
Score = 93.1 bits (221), Expect = 9e-19
Identities = 59/188 (31%), Positives = 101/188 (53%), Gaps = 4/188 (2%)
Frame = +3
Query: 168 EFTKQDIIGHGAFAMVYKGRKRK--NPSQSVAVKVVTKKGIQKASEILVK-EIKILRELT 338
+F ++G G++ V+ RK K + Q A+KV+ K ++ + K E IL E+
Sbjct: 131 QFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKMERDILAEVN 190
Query: 339 ALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSA 518
H +V +H + +Y+++++ GGDL L + +E ++ +LA+LA A+
Sbjct: 191 ---HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDH 247
Query: 519 IHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFAR-FLEEGNMAVTLCGSP 695
+H+ GI++RDLKP+NILL H +KI DFG ++ ++ A + CG+
Sbjct: 248 LHSLGIIYRDLKPENILLDEE------GH-----IKITDFGLSKEAIDHDKRAYSFCGTI 296
Query: 696 MYMAPEVI 719
YMAPEV+
Sbjct: 297 EYMAPEVV 304
>EF560730-1|ABQ59040.1| 686|Homo sapiens PRKG1 protein protein.
Length = 686
Score = 95.5 bits (227), Expect = 2e-19
Identities = 54/187 (28%), Positives = 100/187 (53%), Gaps = 1/187 (0%)
Frame = +3
Query: 168 EFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQ 347
+F D +G G F V + + S++ A+K++ K+ I + + I+ +++
Sbjct: 374 DFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQ--QEHIRSEKQIMQGA 431
Query: 348 HKN-LVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIH 524
H + +V ++ Y+Y++ME C GG+L L+ ++T + + A + EA + +H
Sbjct: 432 HSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLH 491
Query: 525 AKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYM 704
+ GI++RDLKP+N++L H K+ DFGFA+ + G T CG+P Y+
Sbjct: 492 SNGIIYRDLKPENLILDHRGYA-----------KLVDFGFAKKIGFGKKTWTFCGTPEYV 540
Query: 705 APEVIMS 725
APE+I++
Sbjct: 541 APEIILN 547
>BC112101-1|AAI12102.1| 979|Homo sapiens NIMA related kinase 9
protein.
Length = 979
Score = 95.1 bits (226), Expect = 2e-19
Identities = 62/180 (34%), Positives = 97/180 (53%), Gaps = 3/180 (1%)
Frame = +3
Query: 186 IIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQHKNLVA 365
++G GAF R+ ++ S V +V + +K + EI IL LQH N++A
Sbjct: 57 VLGRGAFGEATLYRRTEDDSLVVWKEVDLTRLSEKERRDALNEIVIL---ALLQHDNIIA 113
Query: 366 MHDCMDSPAYVYVVMEYCNGGDLADYL--QTNRLLSETTIQLFLAQLAEAMSAIHAKGIV 539
++ + + +EYCNGG+L D + Q ++L E + +L Q+ A+S IH GI+
Sbjct: 114 YYNHFMDNTTLLIELEYCNGGNLYDKILRQKDKLFEEEMVVWYLFQIVSAVSCIHKAGIL 173
Query: 540 HRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFL-EEGNMAVTLCGSPMYMAPEV 716
HRD+K NI LT + L +K+ D+G A+ L E +MA TL G+P YM+PE+
Sbjct: 174 HRDIKTLNIFLTKANL-----------IKLGDYGLAKKLNSEYSMAETLVGTPYYMSPEL 222
>BC093881-1|AAH93881.1| 979|Homo sapiens NIMA (never in mitosis
gene a)- related kinase 9 protein.
Length = 979
Score = 95.1 bits (226), Expect = 2e-19
Identities = 62/180 (34%), Positives = 97/180 (53%), Gaps = 3/180 (1%)
Frame = +3
Query: 186 IIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQHKNLVA 365
++G GAF R+ ++ S V +V + +K + EI IL LQH N++A
Sbjct: 57 VLGRGAFGEATLYRRTEDDSLVVWKEVDLTRLSEKERRDALNEIVIL---ALLQHDNIIA 113
Query: 366 MHDCMDSPAYVYVVMEYCNGGDLADYL--QTNRLLSETTIQLFLAQLAEAMSAIHAKGIV 539
++ + + +EYCNGG+L D + Q ++L E + +L Q+ A+S IH GI+
Sbjct: 114 YYNHFMDNTTLLIELEYCNGGNLYDKILRQKDKLFEEEMVVWYLFQIVSAVSCIHKAGIL 173
Query: 540 HRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFL-EEGNMAVTLCGSPMYMAPEV 716
HRD+K NI LT + L +K+ D+G A+ L E +MA TL G+P YM+PE+
Sbjct: 174 HRDIKTLNIFLTKANL-----------IKLGDYGLAKKLNSEYSMAETLVGTPYYMSPEL 222
>BC069655-1|AAH69655.1| 390|Homo sapiens PHKG1 protein protein.
Length = 390
Score = 95.1 bits (226), Expect = 2e-19
Identities = 63/197 (31%), Positives = 104/197 (52%), Gaps = 12/197 (6%)
Frame = +3
Query: 165 YE-FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKG--------IQKASEILVKEI 317
YE + ++I+G G ++V + K SQ AVKV+ G +++ E +KE+
Sbjct: 17 YENYEPKEILGRGVSSVVRRCI-HKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEV 75
Query: 318 KILRELTALQHKNLVAMHDCMDSPAYVYVVMEYCNG---GDLADYLQTNRLLSETTIQLF 488
ILR+++ H N++ + D ++ + ++V + + G+L DYL LSE +
Sbjct: 76 DILRKVSG--HPNIIQLKDTYETNTFFFLVFDLFHRMKRGELFDYLTEKATLSEKETRKI 133
Query: 489 LAQLAEAMSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGN 668
+ L E + +H IVHRDLKP+NILL ++ +K+ DFGF+ LE G
Sbjct: 134 MRALLEVICTLHKLNIVHRDLKPENILL-----------DDNMNIKLTDFGFSCQLEPGE 182
Query: 669 MAVTLCGSPMYMAPEVI 719
+CG+P Y+APE+I
Sbjct: 183 RLREVCGTPSYLAPEII 199
>BC062616-1|AAH62616.1| 424|Homo sapiens protein serine kinase H1
protein.
Length = 424
Score = 95.1 bits (226), Expect = 2e-19
Identities = 58/181 (32%), Positives = 98/181 (54%), Gaps = 2/181 (1%)
Frame = +3
Query: 186 IIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQHKNLVA 365
+IG G+F+ V + R Q A+K++ K ++ E+ E+++LR + +H N++
Sbjct: 103 LIGRGSFSRVVRVEHRAT-RQPYAIKMIETK-YREGREVCESELRVLRRV---RHANIIQ 157
Query: 366 MHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIVHR 545
+ + ++ VY+VME GG+L D + +E L + + + +HA GI HR
Sbjct: 158 LVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHALGITHR 217
Query: 546 DLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGN--MAVTLCGSPMYMAPEVI 719
DLKP+N+L H P T D + I DFG A ++G+ + T CG+P Y+APEV+
Sbjct: 218 DLKPENLLYYH----PGT----DSKIIITDFGLASARKKGDDCLMKTTCGTPEYIAPEVL 269
Query: 720 M 722
+
Sbjct: 270 V 270
>BC037268-1|AAH37268.1| 683|Homo sapiens protein kinase C, eta
protein.
Length = 683
Score = 95.1 bits (226), Expect = 2e-19
Identities = 62/194 (31%), Positives = 100/194 (51%), Gaps = 3/194 (1%)
Frame = +3
Query: 156 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI--LVKEIKILR 329
+ ++EF + ++G G+F V R K AVKV+ K I + ++ + E +IL
Sbjct: 352 IDNFEFIR--VLGKGSFGKVMLARV-KETGDLYAVKVLKKDVILQDDDVECTMTEKRILS 408
Query: 330 ELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEA 509
A H L + C +P ++ VME+ NGGDL ++Q +R E + + A++ A
Sbjct: 409 --LARNHPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISA 466
Query: 510 MSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFAR-FLEEGNMAVTLC 686
+ +H KGI++RDLK N+LL H H K+ADFG + + G T C
Sbjct: 467 LMFLHDKGIIYRDLKLDNVLLDHE------GH-----CKLADFGMCKEGICNGVTTATFC 515
Query: 687 GSPMYMAPEVIMSL 728
G+P Y+APE++ +
Sbjct: 516 GTPDYIAPEILQEM 529
>AY080896-1|AAL87410.1| 979|Homo sapiens NIMA-family kinase NERCC1
protein.
Length = 979
Score = 95.1 bits (226), Expect = 2e-19
Identities = 62/180 (34%), Positives = 97/180 (53%), Gaps = 3/180 (1%)
Frame = +3
Query: 186 IIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQHKNLVA 365
++G GAF R+ ++ S V +V + +K + EI IL LQH N++A
Sbjct: 57 VLGRGAFGEATLYRRTEDDSLVVWKEVDLTRLSEKERRDALNEIVIL---ALLQHDNIIA 113
Query: 366 MHDCMDSPAYVYVVMEYCNGGDLADYL--QTNRLLSETTIQLFLAQLAEAMSAIHAKGIV 539
++ + + +EYCNGG+L D + Q ++L E + +L Q+ A+S IH GI+
Sbjct: 114 YYNHFMDNTTLLIELEYCNGGNLYDKILRQKDKLFEEEMVVWYLFQIVSAVSCIHKAGIL 173
Query: 540 HRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFL-EEGNMAVTLCGSPMYMAPEV 716
HRD+K NI LT + L +K+ D+G A+ L E +MA TL G+P YM+PE+
Sbjct: 174 HRDIKTLNIFLTKANL-----------IKLGDYGLAKKLNSEYSMAETLVGTPYYMSPEL 222
>AY048580-1|AAL05428.1| 979|Homo sapiens NIMA-related kinase Nek8
protein.
Length = 979
Score = 95.1 bits (226), Expect = 2e-19
Identities = 62/180 (34%), Positives = 97/180 (53%), Gaps = 3/180 (1%)
Frame = +3
Query: 186 IIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQHKNLVA 365
++G GAF R+ ++ S V +V + +K + EI IL LQH N++A
Sbjct: 57 VLGRGAFGEATLYRRTEDDSLVVWKEVDLTRLSEKERRDALNEIVIL---ALLQHDNIIA 113
Query: 366 MHDCMDSPAYVYVVMEYCNGGDLADYL--QTNRLLSETTIQLFLAQLAEAMSAIHAKGIV 539
++ + + +EYCNGG+L D + Q ++L E + +L Q+ A+S IH GI+
Sbjct: 114 YYNHFMDNTTLLIELEYCNGGNLYDKILRQKDKLFEEEMVVWYLFQIVSAVSCIHKAGIL 173
Query: 540 HRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFL-EEGNMAVTLCGSPMYMAPEV 716
HRD+K NI LT + L +K+ D+G A+ L E +MA TL G+P YM+PE+
Sbjct: 174 HRDIKTLNIFLTKANL-----------IKLGDYGLAKKLNSEYSMAETLVGTPYYMSPEL 222
>AJ272212-1|CAB91984.1| 424|Homo sapiens protein serine kinase
protein.
Length = 424
Score = 95.1 bits (226), Expect = 2e-19
Identities = 58/181 (32%), Positives = 98/181 (54%), Gaps = 2/181 (1%)
Frame = +3
Query: 186 IIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQHKNLVA 365
+IG G+F+ V + R Q A+K++ K ++ E+ E+++LR + +H N++
Sbjct: 103 LIGRGSFSRVVRVEHRAT-RQPYAIKMIETK-YREGREVCESELRVLRRV---RHANIIQ 157
Query: 366 MHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIVHR 545
+ + ++ VY+VME GG+L D + +E L + + + +HA GI HR
Sbjct: 158 LVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHALGITHR 217
Query: 546 DLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGN--MAVTLCGSPMYMAPEVI 719
DLKP+N+L H P T D + I DFG A ++G+ + T CG+P Y+APEV+
Sbjct: 218 DLKPENLLYYH----PGT----DSKIIITDFGLASARKKGDDCLMKTTCGTPEYIAPEVL 269
Query: 720 M 722
+
Sbjct: 270 V 270
>AC007055-5|AAD31940.1| 312|Homo sapiens protein ( Homo sapiens
chromosome 14 clone BAC 201F1 map 14q24.3, complete
sequence. ).
Length = 312
Score = 95.1 bits (226), Expect = 2e-19
Identities = 62/180 (34%), Positives = 97/180 (53%), Gaps = 3/180 (1%)
Frame = +3
Query: 186 IIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQHKNLVA 365
++G GAF R+ ++ S V +V + +K + EI IL LQH N++A
Sbjct: 57 VLGRGAFGEATLYRRTEDDSLVVWKEVDLTRLSEKERRDALNEIVIL---ALLQHDNIIA 113
Query: 366 MHDCMDSPAYVYVVMEYCNGGDLADYL--QTNRLLSETTIQLFLAQLAEAMSAIHAKGIV 539
++ + + +EYCNGG+L D + Q ++L E + +L Q+ A+S IH GI+
Sbjct: 114 YYNHFMDNTTLLIELEYCNGGNLYDKILRQKDKLFEEEMVVWYLFQIVSAVSCIHKAGIL 173
Query: 540 HRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFL-EEGNMAVTLCGSPMYMAPEV 716
HRD+K NI LT + L +K+ D+G A+ L E +MA TL G+P YM+PE+
Sbjct: 174 HRDIKTLNIFLTKANL-----------IKLGDYGLAKKLNSEYSMAETLVGTPYYMSPEL 222
>AB082526-1|BAC02704.1| 1011|Homo sapiens KIAA1995 protein protein.
Length = 1011
Score = 95.1 bits (226), Expect = 2e-19
Identities = 62/180 (34%), Positives = 97/180 (53%), Gaps = 3/180 (1%)
Frame = +3
Query: 186 IIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQHKNLVA 365
++G GAF R+ ++ S V +V + +K + EI IL LQH N++A
Sbjct: 89 VLGRGAFGEATLYRRTEDDSLVVWKEVDLTRLSEKERRDALNEIVIL---ALLQHDNIIA 145
Query: 366 MHDCMDSPAYVYVVMEYCNGGDLADYL--QTNRLLSETTIQLFLAQLAEAMSAIHAKGIV 539
++ + + +EYCNGG+L D + Q ++L E + +L Q+ A+S IH GI+
Sbjct: 146 YYNHFMDNTTLLIELEYCNGGNLYDKILRQKDKLFEEEMVVWYLFQIVSAVSCIHKAGIL 205
Query: 540 HRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFL-EEGNMAVTLCGSPMYMAPEV 716
HRD+K NI LT + L +K+ D+G A+ L E +MA TL G+P YM+PE+
Sbjct: 206 HRDIKTLNIFLTKANL-----------IKLGDYGLAKKLNSEYSMAETLVGTPYYMSPEL 254
>Y16106-1|CAA76073.1| 734|Homo sapiens cGMP-dependant protein
kinase protein.
Length = 734
Score = 94.7 bits (225), Expect = 3e-19
Identities = 62/181 (34%), Positives = 97/181 (53%), Gaps = 2/181 (1%)
Frame = +3
Query: 189 IGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGI--QKASEILVKEIKILRELTALQHKNLV 362
+G G F V + K KN + + A+K + KK I K E + E +IL EL + +V
Sbjct: 459 LGVGGFGRV-ELVKVKNENVAFAMKCIRKKHIVDTKQQEHVYSEKRILEELCS---PFIV 514
Query: 363 AMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIVH 542
++ YVY+++E C GG+L L+ E T + +A + EA +H GI++
Sbjct: 515 KLYRTFKDNKYVYMLLEACLGGELWSILRDRGSFDEPTSKFCVACVTEAFDYLHRLGIIY 574
Query: 543 RDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYMAPEVIM 722
RDLKP+N++L ++ LK+ DFGFA+ + G T CG+P Y+APEVI+
Sbjct: 575 RDLKPENLIL-----------DAEGYLKLVDFGFAKKIGSGQKTWTFCGTPEYVAPEVIL 623
Query: 723 S 725
+
Sbjct: 624 N 624
>X94612-1|CAA64318.1| 762|Homo sapiens Type II cGMP-dependent
protein kinase protein.
Length = 762
Score = 94.7 bits (225), Expect = 3e-19
Identities = 62/181 (34%), Positives = 97/181 (53%), Gaps = 2/181 (1%)
Frame = +3
Query: 189 IGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGI--QKASEILVKEIKILRELTALQHKNLV 362
+G G F V + K KN + + A+K + KK I K E + E +IL EL + +V
Sbjct: 459 LGVGGFGRV-ELVKVKNENVAFAMKCIRKKHIVDTKQQEHVYSEKRILEELCS---PFIV 514
Query: 363 AMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIVH 542
++ YVY+++E C GG+L L+ E T + +A + EA +H GI++
Sbjct: 515 KLYRTFKDNKYVYMLLEACLGGELWSILRDRGSFDEPTSKFCVACVTEAFDYLHRLGIIY 574
Query: 543 RDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYMAPEVIM 722
RDLKP+N++L ++ LK+ DFGFA+ + G T CG+P Y+APEVI+
Sbjct: 575 RDLKPENLIL-----------DAEGYLKLVDFGFAKKIGSGQKTWTFCGTPEYVAPEVIL 623
Query: 723 S 725
+
Sbjct: 624 N 624
>U08316-1|AAA81952.1| 740|Homo sapiens insulin-stimulated protein
kinase 1 protein.
Length = 740
Score = 94.7 bits (225), Expect = 3e-19
Identities = 67/191 (35%), Positives = 98/191 (51%), Gaps = 1/191 (0%)
Frame = +3
Query: 150 IQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILR 329
IQ D K+DI G G+++ V K K + AVK+ I K+ +EI+IL
Sbjct: 416 IQFTDGYEVKEDI-GVGSYS-VCKRCIHKATNMEFAVKI-----IDKSKRDPTEEIEIL- 467
Query: 330 ELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEA 509
L QH N++ + D D YVYVV E GG+L D + + SE L + +
Sbjct: 468 -LRYGQHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKT 526
Query: 510 MSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLE-EGNMAVTLC 686
+ +HA+G+VHRDLKP NIL P +++I DFGFA+ L E + +T C
Sbjct: 527 VEYLHAQGVVHRDLKPSNILYVDESGNPE-------SIRICDFGFAKQLRAENGLLMTPC 579
Query: 687 GSPMYMAPEVI 719
+ ++APEV+
Sbjct: 580 YTANFVAPEVL 590
Score = 90.6 bits (215), Expect = 5e-18
Identities = 54/187 (28%), Positives = 99/187 (52%), Gaps = 3/187 (1%)
Frame = +3
Query: 168 EFTKQDIIGHGAFAMVYKGRK--RKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTA 341
+F ++G G+F V+ +K + Q A+KV+ K ++ + K + + L
Sbjct: 67 QFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERDI--LVE 124
Query: 342 LQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAI 521
+ H +V +H + +Y+++++ GGDL L + +E ++ +LA+LA A+ +
Sbjct: 125 VNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHL 184
Query: 522 HAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFAR-FLEEGNMAVTLCGSPM 698
H+ GI++RDLKP+NILL H +K+ DFG ++ ++ A + CG+
Sbjct: 185 HSLGIIYRDLKPENILLDEE------GH-----IKLTDFGLSKESIDHEKKAYSFCGTVE 233
Query: 699 YMAPEVI 719
YMAPEV+
Sbjct: 234 YMAPEVV 240
>BC096303-1|AAH96303.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 94.7 bits (225), Expect = 3e-19
Identities = 67/191 (35%), Positives = 98/191 (51%), Gaps = 1/191 (0%)
Frame = +3
Query: 150 IQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILR 329
IQ D K+DI G G+++ V K K + AVK+ I K+ +EI+IL
Sbjct: 416 IQFTDGYEVKEDI-GVGSYS-VCKRCIHKATNMEFAVKI-----IDKSKRDPTEEIEIL- 467
Query: 330 ELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEA 509
L QH N++ + D D YVYVV E GG+L D + + SE L + +
Sbjct: 468 -LRYGQHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKT 526
Query: 510 MSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLE-EGNMAVTLC 686
+ +HA+G+VHRDLKP NIL P +++I DFGFA+ L E + +T C
Sbjct: 527 VEYLHAQGVVHRDLKPSNILYVDESGNPE-------SIRICDFGFAKQLRAENGLLMTPC 579
Query: 687 GSPMYMAPEVI 719
+ ++APEV+
Sbjct: 580 YTANFVAPEVL 590
Score = 90.6 bits (215), Expect = 5e-18
Identities = 54/187 (28%), Positives = 99/187 (52%), Gaps = 3/187 (1%)
Frame = +3
Query: 168 EFTKQDIIGHGAFAMVYKGRK--RKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTA 341
+F ++G G+F V+ +K + Q A+KV+ K ++ + K + + L
Sbjct: 67 QFELLKVLGQGSFGKVFLVKKILGSDARQLYAMKVLKKATLKVRDRVRTKMERDI--LVE 124
Query: 342 LQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAI 521
+ H +V +H + +Y+++++ GGDL L + +E ++ +LA+LA A+ +
Sbjct: 125 VNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHL 184
Query: 522 HAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFAR-FLEEGNMAVTLCGSPM 698
H+ GI++RDLKP+NILL H +K+ DFG ++ ++ A + CG+
Sbjct: 185 HSLGIIYRDLKPENILLDEE------GH-----IKLTDFGLSKESIDHEKKAYSFCGTVE 233
Query: 699 YMAPEVI 719
YMAPEV+
Sbjct: 234 YMAPEVV 240
>BC096302-1|AAH96302.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 94.7 bits (225), Expect = 3e-19
Identities = 67/191 (35%), Positives = 98/191 (51%), Gaps = 1/191 (0%)
Frame = +3
Query: 150 IQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILR 329
IQ D K+DI G G+++ V K K + AVK+ I K+ +EI+IL
Sbjct: 416 IQFTDGYEVKEDI-GVGSYS-VCKRCIHKATNMEFAVKI-----IDKSKRDPTEEIEIL- 467
Query: 330 ELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEA 509
L QH N++ + D D YVYVV E GG+L D + + SE L + +
Sbjct: 468 -LRYGQHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKT 526
Query: 510 MSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLE-EGNMAVTLC 686
+ +HA+G+VHRDLKP NIL P +++I DFGFA+ L E + +T C
Sbjct: 527 VEYLHAQGVVHRDLKPSNILYVDESGNPE-------SIRICDFGFAKQLRAENGLLMTPC 579
Query: 687 GSPMYMAPEVI 719
+ ++APEV+
Sbjct: 580 YTANFVAPEVL 590
Score = 90.6 bits (215), Expect = 5e-18
Identities = 54/187 (28%), Positives = 99/187 (52%), Gaps = 3/187 (1%)
Frame = +3
Query: 168 EFTKQDIIGHGAFAMVYKGRK--RKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTA 341
+F ++G G+F V+ +K + Q A+KV+ K ++ + K + + L
Sbjct: 67 QFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERDI--LVE 124
Query: 342 LQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAI 521
+ H +V +H + +Y+++++ GGDL L + +E ++ +LA+LA A+ +
Sbjct: 125 VNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHL 184
Query: 522 HAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFAR-FLEEGNMAVTLCGSPM 698
H+ GI++RDLKP+NILL H +K+ DFG ++ ++ A + CG+
Sbjct: 185 HSLGIIYRDLKPENILLDEE------GH-----IKLTDFGLSKESIDHEKKAYSFCGTVE 233
Query: 699 YMAPEVI 719
YMAPEV+
Sbjct: 234 YMAPEVV 240
>BC096301-1|AAH96301.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 94.7 bits (225), Expect = 3e-19
Identities = 67/191 (35%), Positives = 98/191 (51%), Gaps = 1/191 (0%)
Frame = +3
Query: 150 IQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILR 329
IQ D K+DI G G+++ V K K + AVK+ I K+ +EI+IL
Sbjct: 416 IQFTDGYEVKEDI-GVGSYS-VCKRCIHKATNMEFAVKI-----IDKSKRDPTEEIEIL- 467
Query: 330 ELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEA 509
L QH N++ + D D YVYVV E GG+L D + + SE L + +
Sbjct: 468 -LRYGQHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKT 526
Query: 510 MSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLE-EGNMAVTLC 686
+ +HA+G+VHRDLKP NIL P +++I DFGFA+ L E + +T C
Sbjct: 527 VEYLHAQGVVHRDLKPSNILYVDESGNPE-------SIRICDFGFAKQLRAENGLLMTPC 579
Query: 687 GSPMYMAPEVI 719
+ ++APEV+
Sbjct: 580 YTANFVAPEVL 590
Score = 90.6 bits (215), Expect = 5e-18
Identities = 54/187 (28%), Positives = 99/187 (52%), Gaps = 3/187 (1%)
Frame = +3
Query: 168 EFTKQDIIGHGAFAMVYKGRK--RKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTA 341
+F ++G G+F V+ +K + Q A+KV+ K ++ + K + + L
Sbjct: 67 QFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERDI--LVE 124
Query: 342 LQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAI 521
+ H +V +H + +Y+++++ GGDL L + +E ++ +LA+LA A+ +
Sbjct: 125 VNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHL 184
Query: 522 HAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFAR-FLEEGNMAVTLCGSPM 698
H+ GI++RDLKP+NILL H +K+ DFG ++ ++ A + CG+
Sbjct: 185 HSLGIIYRDLKPENILLDEE------GH-----IKLTDFGLSKESIDHEKKAYSFCGTVE 233
Query: 699 YMAPEVI 719
YMAPEV+
Sbjct: 234 YMAPEVV 240
>AL807772-3|CAI39687.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 94.7 bits (225), Expect = 3e-19
Identities = 67/191 (35%), Positives = 98/191 (51%), Gaps = 1/191 (0%)
Frame = +3
Query: 150 IQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILR 329
IQ D K+DI G G+++ V K K + AVK+ I K+ +EI+IL
Sbjct: 416 IQFTDGYEVKEDI-GVGSYS-VCKRCIHKATNMEFAVKI-----IDKSKRDPTEEIEIL- 467
Query: 330 ELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEA 509
L QH N++ + D D YVYVV E GG+L D + + SE L + +
Sbjct: 468 -LRYGQHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKT 526
Query: 510 MSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLE-EGNMAVTLC 686
+ +HA+G+VHRDLKP NIL P +++I DFGFA+ L E + +T C
Sbjct: 527 VEYLHAQGVVHRDLKPSNILYVDESGNPE-------SIRICDFGFAKQLRAENGLLMTPC 579
Query: 687 GSPMYMAPEVI 719
+ ++APEV+
Sbjct: 580 YTANFVAPEVL 590
Score = 90.6 bits (215), Expect = 5e-18
Identities = 54/187 (28%), Positives = 99/187 (52%), Gaps = 3/187 (1%)
Frame = +3
Query: 168 EFTKQDIIGHGAFAMVYKGRK--RKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTA 341
+F ++G G+F V+ +K + Q A+KV+ K ++ + K + + L
Sbjct: 67 QFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERDI--LVE 124
Query: 342 LQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAI 521
+ H +V +H + +Y+++++ GGDL L + +E ++ +LA+LA A+ +
Sbjct: 125 VNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHL 184
Query: 522 HAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFAR-FLEEGNMAVTLCGSPM 698
H+ GI++RDLKP+NILL H +K+ DFG ++ ++ A + CG+
Sbjct: 185 HSLGIIYRDLKPENILLDEE------GH-----IKLTDFGLSKESIDHEKKAYSFCGTVE 233
Query: 699 YMAPEVI 719
YMAPEV+
Sbjct: 234 YMAPEVV 240
>AL732366-2|CAI40548.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 94.7 bits (225), Expect = 3e-19
Identities = 67/191 (35%), Positives = 98/191 (51%), Gaps = 1/191 (0%)
Frame = +3
Query: 150 IQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILR 329
IQ D K+DI G G+++ V K K + AVK+ I K+ +EI+IL
Sbjct: 416 IQFTDGYEVKEDI-GVGSYS-VCKRCIHKATNMEFAVKI-----IDKSKRDPTEEIEIL- 467
Query: 330 ELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEA 509
L QH N++ + D D YVYVV E GG+L D + + SE L + +
Sbjct: 468 -LRYGQHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKT 526
Query: 510 MSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLE-EGNMAVTLC 686
+ +HA+G+VHRDLKP NIL P +++I DFGFA+ L E + +T C
Sbjct: 527 VEYLHAQGVVHRDLKPSNILYVDESGNPE-------SIRICDFGFAKQLRAENGLLMTPC 579
Query: 687 GSPMYMAPEVI 719
+ ++APEV+
Sbjct: 580 YTANFVAPEVL 590
Score = 90.6 bits (215), Expect = 5e-18
Identities = 54/187 (28%), Positives = 99/187 (52%), Gaps = 3/187 (1%)
Frame = +3
Query: 168 EFTKQDIIGHGAFAMVYKGRK--RKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTA 341
+F ++G G+F V+ +K + Q A+KV+ K ++ + K + + L
Sbjct: 67 QFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERDI--LVE 124
Query: 342 LQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAI 521
+ H +V +H + +Y+++++ GGDL L + +E ++ +LA+LA A+ +
Sbjct: 125 VNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHL 184
Query: 522 HAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFAR-FLEEGNMAVTLCGSPM 698
H+ GI++RDLKP+NILL H +K+ DFG ++ ++ A + CG+
Sbjct: 185 HSLGIIYRDLKPENILLDEE------GH-----IKLTDFGLSKESIDHEKKAYSFCGTVE 233
Query: 699 YMAPEVI 719
YMAPEV+
Sbjct: 234 YMAPEVV 240
>AF080000-1|AAD23915.1| 802|Homo sapiens RSK-like protein kinase
RLPK protein.
Length = 802
Score = 94.7 bits (225), Expect = 3e-19
Identities = 60/186 (32%), Positives = 100/186 (53%), Gaps = 5/186 (2%)
Frame = +3
Query: 177 KQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQ--- 347
K +G G+F++ K +K+ +Q+ AVK+++K+ E +E+TAL+
Sbjct: 428 KDKPLGEGSFSICRKCVHKKS-NQAFAVKIISKR----------MEANTQKEITALKLCE 476
Query: 348 -HKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIH 524
H N+V +H+ + ++VME NGG+L + ++ + SET + +L A+S +H
Sbjct: 477 GHPNIVKLHEVFHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMH 536
Query: 525 AKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAV-TLCGSPMY 701
G+VHRDLKP+N+L T ++ +KI DFGFAR N + T C + Y
Sbjct: 537 DVGVVHRDLKPENLLF--------TDENDNLEIKIIDFGFARLKPPDNQPLKTPCFTLHY 588
Query: 702 MAPEVI 719
APE++
Sbjct: 589 AAPELL 594
Score = 78.2 bits (184), Expect = 3e-14
Identities = 55/196 (28%), Positives = 102/196 (52%), Gaps = 7/196 (3%)
Frame = +3
Query: 153 QVGDYEFTKQDIIGHGAFAMVYKGRKRK--NPSQSVAVKVVTKKGI-QKA--SEILVKEI 317
+VG F ++G GA+ V+ RK + + A+KV+ K I QKA +E E
Sbjct: 43 KVGIENFELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTER 102
Query: 318 KILRELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQ 497
++L + Q LV +H + ++++++Y NGG+L +L +E +Q+++ +
Sbjct: 103 QVLEHIR--QSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGE 160
Query: 498 LAEAMSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFAR--FLEEGNM 671
+ A+ +H GI++RD+K +NILL S+ + + DFG ++ +E
Sbjct: 161 IVLALEHLHKLGIIYRDIKLENILL-----------DSNGHVVLTDFGLSKEFVADETER 209
Query: 672 AVTLCGSPMYMAPEVI 719
A + CG+ YMAP+++
Sbjct: 210 AYSFCGTIEYMAPDIV 225
>AF074393-1|AAC31171.1| 802|Homo sapiens nuclear mitogen- and
stress-activated protein kinase-1 protein.
Length = 802
Score = 94.7 bits (225), Expect = 3e-19
Identities = 60/186 (32%), Positives = 100/186 (53%), Gaps = 5/186 (2%)
Frame = +3
Query: 177 KQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQ--- 347
K +G G+F++ K +K+ +Q+ AVK+++K+ E +E+TAL+
Sbjct: 428 KDKPLGEGSFSICRKCVHKKS-NQAFAVKIISKR----------MEANTQKEITALKLCE 476
Query: 348 -HKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIH 524
H N+V +H+ + ++VME NGG+L + ++ + SET + +L A+S +H
Sbjct: 477 GHPNIVKLHEVFHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMH 536
Query: 525 AKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAV-TLCGSPMY 701
G+VHRDLKP+N+L T ++ +KI DFGFAR N + T C + Y
Sbjct: 537 DVGVVHRDLKPENLLF--------TDENDNLEIKIIDFGFARLKPPDNQPLKTPCFTLHY 588
Query: 702 MAPEVI 719
APE++
Sbjct: 589 AAPELL 594
Score = 78.2 bits (184), Expect = 3e-14
Identities = 55/196 (28%), Positives = 102/196 (52%), Gaps = 7/196 (3%)
Frame = +3
Query: 153 QVGDYEFTKQDIIGHGAFAMVYKGRKRK--NPSQSVAVKVVTKKGI-QKA--SEILVKEI 317
+VG F ++G GA+ V+ RK + + A+KV+ K I QKA +E E
Sbjct: 43 KVGIENFELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTER 102
Query: 318 KILRELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQ 497
++L + Q LV +H + ++++++Y NGG+L +L +E +Q+++ +
Sbjct: 103 QVLEHIR--QSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGE 160
Query: 498 LAEAMSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFAR--FLEEGNM 671
+ A+ +H GI++RD+K +NILL S+ + + DFG ++ +E
Sbjct: 161 IVLALEHLHKLGIIYRDIKLENILL-----------DSNGHVVLTDFGLSKEFVADETER 209
Query: 672 AVTLCGSPMYMAPEVI 719
A + CG+ YMAP+++
Sbjct: 210 AYSFCGTIEYMAPDIV 225
>AB208933-1|BAD92170.1| 806|Homo sapiens ribosomal protein S6 kinase,
90kDa, polypeptide 3 variant protein.
Length = 806
Score = 94.7 bits (225), Expect = 3e-19
Identities = 67/191 (35%), Positives = 98/191 (51%), Gaps = 1/191 (0%)
Frame = +3
Query: 150 IQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILR 329
IQ D K+DI G G+++ V K K + AVK+ I K+ +EI+IL
Sbjct: 482 IQFTDGYEVKEDI-GVGSYS-VCKRCIHKATNMEFAVKI-----IDKSKRDPTEEIEIL- 533
Query: 330 ELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEA 509
L QH N++ + D D YVYVV E GG+L D + + SE L + +
Sbjct: 534 -LRYGQHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKT 592
Query: 510 MSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLE-EGNMAVTLC 686
+ +HA+G+VHRDLKP NIL P +++I DFGFA+ L E + +T C
Sbjct: 593 VEYLHAQGVVHRDLKPSNILYVDESGNPE-------SIRICDFGFAKQLRAENGLLMTPC 645
Query: 687 GSPMYMAPEVI 719
+ ++APEV+
Sbjct: 646 YTANFVAPEVL 656
Score = 90.6 bits (215), Expect = 5e-18
Identities = 54/187 (28%), Positives = 99/187 (52%), Gaps = 3/187 (1%)
Frame = +3
Query: 168 EFTKQDIIGHGAFAMVYKGRK--RKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTA 341
+F ++G G+F V+ +K + Q A+KV+ K ++ + K + + L
Sbjct: 134 QFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERDI--LVE 191
Query: 342 LQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAI 521
+ H +V +H + +Y+++++ GGDL L + +E ++ +LA+LA A+ +
Sbjct: 192 VNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHL 251
Query: 522 HAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFAR-FLEEGNMAVTLCGSPM 698
H+ GI++RDLKP+NILL H +K+ DFG ++ ++ A + CG+
Sbjct: 252 HSLGIIYRDLKPENILLDEE------GH-----IKLTDFGLSKESIDHEKKAYSFCGTVE 300
Query: 699 YMAPEVI 719
YMAPEV+
Sbjct: 301 YMAPEVV 307
>AB102662-1|BAC81131.1| 726|Homo sapiens RPS6KA3 protein.
Length = 726
Score = 94.7 bits (225), Expect = 3e-19
Identities = 67/191 (35%), Positives = 98/191 (51%), Gaps = 1/191 (0%)
Frame = +3
Query: 150 IQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILR 329
IQ D K+DI G G+++ V K K + AVK+ I K+ +EI+IL
Sbjct: 402 IQFTDGYEVKEDI-GVGSYS-VCKRCIHKATNMEFAVKI-----IDKSKRDPTEEIEIL- 453
Query: 330 ELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEA 509
L QH N++ + D D YVYVV E GG+L D + + SE L + +
Sbjct: 454 -LRYGQHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKT 512
Query: 510 MSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLE-EGNMAVTLC 686
+ +HA+G+VHRDLKP NIL P +++I DFGFA+ L E + +T C
Sbjct: 513 VEYLHAQGVVHRDLKPSNILYVDESGNPE-------SIRICDFGFAKQLRAENGLLMTPC 565
Query: 687 GSPMYMAPEVI 719
+ ++APEV+
Sbjct: 566 YTANFVAPEVL 576
Score = 90.6 bits (215), Expect = 5e-18
Identities = 54/187 (28%), Positives = 99/187 (52%), Gaps = 3/187 (1%)
Frame = +3
Query: 168 EFTKQDIIGHGAFAMVYKGRK--RKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTA 341
+F ++G G+F V+ +K + Q A+KV+ K ++ + K + + L
Sbjct: 53 QFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERDI--LVE 110
Query: 342 LQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAI 521
+ H +V +H + +Y+++++ GGDL L + +E ++ +LA+LA A+ +
Sbjct: 111 VNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHL 170
Query: 522 HAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFAR-FLEEGNMAVTLCGSPM 698
H+ GI++RDLKP+NILL H +K+ DFG ++ ++ A + CG+
Sbjct: 171 HSLGIIYRDLKPENILLDEE------GH-----IKLTDFGLSKESIDHEKKAYSFCGTVE 219
Query: 699 YMAPEVI 719
YMAPEV+
Sbjct: 220 YMAPEVV 226
>BC109097-1|AAI09098.2| 795|Homo sapiens MLCK protein protein.
Length = 795
Score = 94.3 bits (224), Expect = 4e-19
Identities = 64/196 (32%), Positives = 103/196 (52%), Gaps = 1/196 (0%)
Frame = +3
Query: 135 VKMEVIQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKE 314
VK I G YE + +++G G F V++ + K+ +A K++ K K E + E
Sbjct: 480 VKETSISAG-YEVCQHEVLGGGRFGQVHRCTE-KSTGLPLAAKIIKVKSA-KDREDVKNE 536
Query: 315 IKILRELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRL-LSETTIQLFL 491
I I+ +L+ H NL+ ++D +S +VMEY +GG+L D + + L+E + LF
Sbjct: 537 INIMNQLS---HVNLIQLYDAFESKHSCTLVMEYVDGGELFDRITDEKYHLTELDVVLFT 593
Query: 492 AQLAEAMSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNM 671
Q+ E + +H I+H DLKP+NIL + +T H +KI DFG AR +
Sbjct: 594 RQICEGVHYLHQHYILHLDLKPENILCVN-----QTGH----QIKIIDFGLARRYKPREK 644
Query: 672 AVTLCGSPMYMAPEVI 719
G+P ++APEV+
Sbjct: 645 LKVNFGTPEFLAPEVV 660
>AJ247087-1|CAC42766.1| 795|Homo sapiens myosin light chain kinase
(MLCK) protein.
Length = 795
Score = 94.3 bits (224), Expect = 4e-19
Identities = 64/196 (32%), Positives = 103/196 (52%), Gaps = 1/196 (0%)
Frame = +3
Query: 135 VKMEVIQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKE 314
VK I G YE + +++G G F V++ + K+ +A K++ K K E + E
Sbjct: 480 VKETSISAG-YEVCQHEVLGGGRFGQVHRCTE-KSTGLPLAAKIIKVKSA-KDREDVKNE 536
Query: 315 IKILRELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRL-LSETTIQLFL 491
I I+ +L+ H NL+ ++D +S +VMEY +GG+L D + + L+E + LF
Sbjct: 537 INIMNQLS---HVNLIQLYDAFESKHSCTLVMEYVDGGELFDRITDEKYHLTELDVVLFT 593
Query: 492 AQLAEAMSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNM 671
Q+ E + +H I+H DLKP+NIL + +T H +KI DFG AR +
Sbjct: 594 RQICEGVHYLHQHYILHLDLKPENILCVN-----QTGH----QIKIIDFGLARRYKPREK 644
Query: 672 AVTLCGSPMYMAPEVI 719
G+P ++APEV+
Sbjct: 645 LKVNFGTPEFLAPEVV 660
>M55284-1|AAA60100.1| 682|Homo sapiens protein kinase C-L protein.
Length = 682
Score = 93.9 bits (223), Expect = 5e-19
Identities = 62/194 (31%), Positives = 99/194 (51%), Gaps = 3/194 (1%)
Frame = +3
Query: 156 VGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEI--LVKEIKILR 329
+ ++EF + ++G G+F V R K AVKV+ K I ++ + E +IL
Sbjct: 351 IDNFEFIR--VLGKGSFGKVMLARV-KETGDLYAVKVLKKDVILLDDDVECTMTEKRILS 407
Query: 330 ELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEA 509
A H L + C +P ++ VME+ NGGDL ++Q +R E + + A++ A
Sbjct: 408 --LARNHPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISA 465
Query: 510 MSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFAR-FLEEGNMAVTLC 686
+ +H KGI++RDLK N+LL H H K+ADFG + + G T C
Sbjct: 466 LMFLHDKGIIYRDLKLDNVLLDHE------GH-----CKLADFGMCKEGICNGVTTATFC 514
Query: 687 GSPMYMAPEVIMSL 728
G+P Y+APE++ +
Sbjct: 515 GTPDYIAPEILQEM 528
>BC034044-1|AAH34044.1| 527|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 527
Score = 93.9 bits (223), Expect = 5e-19
Identities = 61/188 (32%), Positives = 100/188 (53%), Gaps = 2/188 (1%)
Frame = +3
Query: 162 DYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVV-TKKGIQKASEILVKEIKILRELT 338
DY+ ++ +G GAF++V + K K P+Q A K++ TKK + + L +E +I R
Sbjct: 13 DYQLFEE--LGKGAFSVVRRCVK-KTPTQEYAAKIINTKKLSARDHQKLEREARICR--- 66
Query: 339 ALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSA 518
L+H N+V +HD + + Y+V + GG+L + + SE + Q+ E+++
Sbjct: 67 LLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNH 126
Query: 519 IHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMA-VTLCGSP 695
IH IVHRDLKP+N+LL +K+ADFG A ++ A G+P
Sbjct: 127 IHQHDIVHRDLKPENLLLASKC--------KGAAVKLADFGLAIEVQGEQQAWFGFAGTP 178
Query: 696 MYMAPEVI 719
Y++PEV+
Sbjct: 179 GYLSPEVL 186
>AL834498-1|CAD39156.1| 716|Homo sapiens hypothetical protein
protein.
Length = 716
Score = 93.9 bits (223), Expect = 5e-19
Identities = 57/178 (32%), Positives = 96/178 (53%)
Frame = +3
Query: 186 IIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQHKNLVA 365
+IG G FA+V + R + A+K++ K ++ E+ ILR + +H N++
Sbjct: 349 VIGDGNFAVVKECIDRST-GKEFALKIIDKAKCCGKEHLIENEVSILRRV---KHPNIIM 404
Query: 366 MHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIVHR 545
+ + M++ +++VME GGDL D + ++ +E + LA A+ +H IVHR
Sbjct: 405 LVEEMETATELFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHGLSIVHR 464
Query: 546 DLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYMAPEVI 719
D+KP+N+L+ P T +LK+ DFG A +E T+CG+P Y+APE+I
Sbjct: 465 DIKPENLLVCE--YPDGTK-----SLKLGDFGLATVVE--GPLYTVCGTPTYVAPEII 513
>AC093748-1|AAY40983.1| 443|Homo sapiens unknown protein.
Length = 443
Score = 93.9 bits (223), Expect = 5e-19
Identities = 57/178 (32%), Positives = 96/178 (53%)
Frame = +3
Query: 186 IIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQHKNLVA 365
+IG G FA+V + R + A+K++ K ++ E+ ILR + +H N++
Sbjct: 146 VIGDGNFAVVKECIDRST-GKEFALKIIDKAKCCGKEHLIENEVSILRRV---KHPNIIM 201
Query: 366 MHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIVHR 545
+ + M++ +++VME GGDL D + ++ +E + LA A+ +H IVHR
Sbjct: 202 LVEEMETATELFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHGLSIVHR 261
Query: 546 DLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYMAPEVI 719
D+KP+N+L+ P T +LK+ DFG A +E T+CG+P Y+APE+I
Sbjct: 262 DIKPENLLVCE--YPDGTK-----SLKLGDFGLATVVE--GPLYTVCGTPTYVAPEII 310
>AB209181-1|BAD92418.1| 796|Homo sapiens Hypothetical protein
DKFZp761I032 variant protein.
Length = 796
Score = 93.9 bits (223), Expect = 5e-19
Identities = 57/178 (32%), Positives = 96/178 (53%)
Frame = +3
Query: 186 IIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQHKNLVA 365
+IG G FA+V + R + A+K++ K ++ E+ ILR + +H N++
Sbjct: 429 VIGDGNFAVVKECIDRST-GKEFALKIIDKAKCCGKEHLIENEVSILRRV---KHPNIIM 484
Query: 366 MHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIVHR 545
+ + M++ +++VME GGDL D + ++ +E + LA A+ +H IVHR
Sbjct: 485 LVEEMETATELFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHGLSIVHR 544
Query: 546 DLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYMAPEVI 719
D+KP+N+L+ P T +LK+ DFG A +E T+CG+P Y+APE+I
Sbjct: 545 DIKPENLLVCE--YPDGTK-----SLKLGDFGLATVVE--GPLYTVCGTPTYVAPEII 593
>D70899-1|BAA18934.1| 762|Homo sapiens cGMP-dependent protein
kinase II protein.
Length = 762
Score = 93.5 bits (222), Expect = 7e-19
Identities = 58/168 (34%), Positives = 91/168 (54%), Gaps = 2/168 (1%)
Frame = +3
Query: 228 KRKNPSQSVAVKVVTKKGI--QKASEILVKEIKILRELTALQHKNLVAMHDCMDSPAYVY 401
K KN + + A+K + KK I K E + E +IL EL + +V ++ YVY
Sbjct: 471 KVKNENVAFAMKCIRKKHIVDTKQQEHVYSEKRILEELCS---PFIVKLYRTFKDNKYVY 527
Query: 402 VVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAKGIVHRDLKPQNILLTHS 581
+++E C GG+L L+ E T + +A + EA +H GI++RDLKP+N++L
Sbjct: 528 MLLEACLGGELWSILRDRGSFDEPTSKFCVACVTEAFDYLHRLGIIYRDLKPENLIL--- 584
Query: 582 ILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYMAPEVIMS 725
++ LK+ DFGFA+ + G T CG+P Y+APEVI++
Sbjct: 585 --------DAEGYLKLVDFGFAKKIGSGQKTWTFCGTPEYVAPEVILN 624
>CR536581-1|CAG38818.1| 429|Homo sapiens SGKL protein.
Length = 429
Score = 93.5 bits (222), Expect = 7e-19
Identities = 64/189 (33%), Positives = 102/189 (53%), Gaps = 3/189 (1%)
Frame = +3
Query: 162 DYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGI--QKASEILVKEIKILREL 335
D++F K +IG G+F V KRK + AVKV+ KK + +K + ++ E +L L
Sbjct: 94 DFDFLK--VIGKGSFGKVLLA-KRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVL--L 148
Query: 336 TALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMS 515
++H LV +H + +Y V+++ NGG+L +LQ R E + + A++A A+
Sbjct: 149 KNVKHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALG 208
Query: 516 AIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFAR-FLEEGNMAVTLCGS 692
+H+ IV+RDLKP+NILL H + + DFG + + + T CG+
Sbjct: 209 YLHSIKIVYRDLKPENILL------DSVGH-----VVLTDFGLCKEGIAISDTTTTFCGT 257
Query: 693 PMYMAPEVI 719
P Y+APEVI
Sbjct: 258 PEYLAPEVI 266
>BC015326-1|AAH15326.1| 496|Homo sapiens serum/glucocorticoid
regulated kinase family, member 3 protein.
Length = 496
Score = 93.5 bits (222), Expect = 7e-19
Identities = 64/189 (33%), Positives = 102/189 (53%), Gaps = 3/189 (1%)
Frame = +3
Query: 162 DYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGI--QKASEILVKEIKILREL 335
D++F K +IG G+F V KRK + AVKV+ KK + +K + ++ E +L L
Sbjct: 161 DFDFLK--VIGKGSFGKVLLA-KRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVL--L 215
Query: 336 TALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMS 515
++H LV +H + +Y V+++ NGG+L +LQ R E + + A++A A+
Sbjct: 216 KNVKHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALG 275
Query: 516 AIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFAR-FLEEGNMAVTLCGS 692
+H+ IV+RDLKP+NILL H + + DFG + + + T CG+
Sbjct: 276 YLHSIKIVYRDLKPENILL------DSVGH-----VVLTDFGLCKEGIAISDTTTTFCGT 324
Query: 693 PMYMAPEVI 719
P Y+APEVI
Sbjct: 325 PEYLAPEVI 333
>AK223523-1|BAD97243.1| 496|Homo sapiens serum/glucocorticoid
regulated kinase-like isoform 1 variant protein.
Length = 496
Score = 93.5 bits (222), Expect = 7e-19
Identities = 64/189 (33%), Positives = 102/189 (53%), Gaps = 3/189 (1%)
Frame = +3
Query: 162 DYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGI--QKASEILVKEIKILREL 335
D++F K +IG G+F V KRK + AVKV+ KK + +K + ++ E +L L
Sbjct: 161 DFDFLK--VIGKGSFGKVLLA-KRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVL--L 215
Query: 336 TALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMS 515
++H LV +H + +Y V+++ NGG+L +LQ R E + + A++A A+
Sbjct: 216 KNVKHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALG 275
Query: 516 AIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFAR-FLEEGNMAVTLCGS 692
+H+ IV+RDLKP+NILL H + + DFG + + + T CG+
Sbjct: 276 YLHSIKIVYRDLKPENILL------DSVGH-----VVLTDFGLCKEGIAISDTTTTFCGT 324
Query: 693 PMYMAPEVI 719
P Y+APEVI
Sbjct: 325 PEYLAPEVI 333
>AF169035-1|AAF12758.1| 429|Homo sapiens protein kinase protein.
Length = 429
Score = 93.5 bits (222), Expect = 7e-19
Identities = 64/189 (33%), Positives = 102/189 (53%), Gaps = 3/189 (1%)
Frame = +3
Query: 162 DYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGI--QKASEILVKEIKILREL 335
D++F K +IG G+F V KRK + AVKV+ KK + +K + ++ E +L L
Sbjct: 94 DFDFLK--VIGKGSFGKVLLA-KRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVL--L 148
Query: 336 TALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMS 515
++H LV +H + +Y V+++ NGG+L +LQ R E + + A++A A+
Sbjct: 149 KNVKHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALG 208
Query: 516 AIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFAR-FLEEGNMAVTLCGS 692
+H+ IV+RDLKP+NILL H + + DFG + + + T CG+
Sbjct: 209 YLHSIKIVYRDLKPENILL------DSVGH-----VVLTDFGLCKEGIAISDTTTTFCGT 257
Query: 693 PMYMAPEVI 719
P Y+APEVI
Sbjct: 258 PEYLAPEVI 266
>L07598-1|AAC82496.1| 540|Homo sapiens ribosomal protein S6 kinase
2 protein.
Length = 540
Score = 93.1 bits (221), Expect = 9e-19
Identities = 59/188 (31%), Positives = 101/188 (53%), Gaps = 4/188 (2%)
Frame = +3
Query: 168 EFTKQDIIGHGAFAMVYKGRKRK--NPSQSVAVKVVTKKGIQKASEILVK-EIKILRELT 338
+F ++G G++ V+ RK K + Q A+KV+ K ++ + K E IL E+
Sbjct: 59 QFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKMERDILAEVN 118
Query: 339 ALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSA 518
H +V +H + +Y+++++ GGDL L + +E ++ +LA+LA A+
Sbjct: 119 ---HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDH 175
Query: 519 IHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFAR-FLEEGNMAVTLCGSP 695
+H+ GI++RDLKP+NILL H +KI DFG ++ ++ A + CG+
Sbjct: 176 LHSLGIIYRDLKPENILLDEE------GH-----IKITDFGLSKEAIDHDKRAYSFCGTI 224
Query: 696 MYMAPEVI 719
YMAPEV+
Sbjct: 225 EYMAPEVV 232
Score = 75.8 bits (178), Expect = 2e-13
Identities = 52/135 (38%), Positives = 73/135 (54%)
Frame = +3
Query: 165 YEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTAL 344
YE K+DI G G+++ V K K AVK++ K + SE EI+IL L
Sbjct: 416 YEI-KEDI-GVGSYS-VCKRCVHKATDTEYAVKIIGKSK-RDPSE----EIEIL--LRYG 465
Query: 345 QHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIH 524
QH N++ + D D +VY+VME GG+L D + R SE L + + M +H
Sbjct: 466 QHPNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLH 525
Query: 525 AKGIVHRDLKPQNIL 569
++G+VHRDLKP NIL
Sbjct: 526 SQGVVHRDLKPSNIL 540
>AL023754-2|CAI19990.1| 245|Homo sapiens
calcium/calmodulin-dependent protein kinase IG protein.
Length = 245
Score = 92.7 bits (220), Expect = 1e-18
Identities = 56/178 (31%), Positives = 98/178 (55%)
Frame = +3
Query: 171 FTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILRELTALQH 350
F +++G GAF+ V+ ++R + A+K + K + S L EI +L+++ +H
Sbjct: 23 FIFMEVLGSGAFSEVFLVKQRLT-GKLFALKCIKKSPAFRDSS-LENEIAVLKKI---KH 77
Query: 351 KNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAIHAK 530
+N+V + D +S + Y+VM+ +GG+L D + + +E L + Q+ A+ +H
Sbjct: 78 ENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLHEN 137
Query: 531 GIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMYM 704
GIVHRDLKP+N+L TP + + I DFG ++ + G M+ T CG+P Y+
Sbjct: 138 GIVHRDLKPENLLYL-------TPEENS-KIMITDFGLSKMEQNGIMS-TACGTPGYV 186
>BC048980-1|AAH48980.1| 574|Homo sapiens protein kinase,
AMP-activated, alpha 1 catalytic subunit protein.
Length = 574
Score = 92.3 bits (219), Expect = 2e-18
Identities = 60/205 (29%), Positives = 104/205 (50%), Gaps = 15/205 (7%)
Frame = +3
Query: 150 IQVGDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQKASEILVKEIKILR 329
+++G Y D +G G F V G K + VAVK++ ++ I ++ +++ K + ++
Sbjct: 22 VKIGHYILG--DTLGVGTFGKVKVG-KHELTGHKVAVKILNRQKI-RSLDVVGKIRREIQ 77
Query: 330 ELTALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTN---------------RLL 464
L +H +++ ++ + +P+ +++VMEY +GG+L DY+ N + L
Sbjct: 78 NLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRKSDVPGVVKTGSTKEL 137
Query: 465 SETTIQLFLAQLAEAMSAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGF 644
E + Q+ + H +VHRDLKP+N+LL + + KIADFG
Sbjct: 138 DEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLD-----------AHMNAKIADFGL 186
Query: 645 ARFLEEGNMAVTLCGSPMYMAPEVI 719
+ + +G T CGSP Y APEVI
Sbjct: 187 SNMMSDGEFLRTSCGSPNYAAPEVI 211
>AF226044-1|AAF86944.1| 765|Homo sapiens HSNFRK protein.
Length = 765
Score = 92.3 bits (219), Expect = 2e-18
Identities = 58/190 (30%), Positives = 102/190 (53%), Gaps = 2/190 (1%)
Frame = +3
Query: 159 GDYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGIQK-ASEILVKEIKILREL 335
G Y+ K +G G FA+V K + + VAVKV+ K + A+ L +E++ ++
Sbjct: 14 GLYDLDKT--LGRGHFAVV-KLARHVFTGEKVAVKVIDKTKLDTLATGHLFQEVRCMK-- 68
Query: 336 TALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRL-LSETTIQLFLAQLAEAM 512
+QH N+V +++ +D+ +Y+++E + GD+ DY+ + L+E + + AQ+ A+
Sbjct: 69 -LVQHPNIVRLYEVIDTQTKLYLILELGDEGDMFDYIMKHEEGLNEDLPKKYFAQIVHAI 127
Query: 513 SAIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGS 692
S H +VHRDLKP+N++ +K+ DFGF+ + G T CGS
Sbjct: 128 SYCHKLHVVHRDLKPENVVFFEK----------QGLVKLTDFGFSNKFQPGKKLTTSCGS 177
Query: 693 PMYMAPEVIM 722
Y APE+++
Sbjct: 178 LAYSAPEILL 187
>AF085233-1|AAF27051.2| 496|Homo sapiens SGK-like protein SGKL
protein.
Length = 496
Score = 92.3 bits (219), Expect = 2e-18
Identities = 63/189 (33%), Positives = 102/189 (53%), Gaps = 3/189 (1%)
Frame = +3
Query: 162 DYEFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGI--QKASEILVKEIKILREL 335
D++F K +IG G+F V KRK + AVKV+ KK + +K + ++ E +L L
Sbjct: 161 DFDFLK--VIGKGSFGKVLLA-KRKLDGKVYAVKVLQKKIVLNRKEQKHIMAERNVL--L 215
Query: 336 TALQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMS 515
++H LV +H + +Y V+++ NGG+L +LQ R E + + A++A A+
Sbjct: 216 KNVKHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALG 275
Query: 516 AIHAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFAR-FLEEGNMAVTLCGS 692
+H+ IV+RDLKP+NIL+ H + + DFG + + + T CG+
Sbjct: 276 YLHSIKIVYRDLKPENILV------DSVGH-----VVLTDFGLCKEGIAISDTTTTFCGT 324
Query: 693 PMYMAPEVI 719
P Y+APEVI
Sbjct: 325 PEYLAPEVI 333
>X85545-1|CAA59733.1| 358|Homo sapiens protein kinase protein.
Length = 358
Score = 91.5 bits (217), Expect = 3e-18
Identities = 64/188 (34%), Positives = 99/188 (52%), Gaps = 2/188 (1%)
Frame = +3
Query: 168 EFTKQDIIGHGAFAMVYKGRKRKNPSQSVAVKVVTKKGI--QKASEILVKEIKILRELTA 341
+F +G G F V+ K K A+KV++ + K + + E +L+E++
Sbjct: 48 DFDTLATVGTGTFGRVHLV-KEKTAKHFFALKVMSIPDVIRLKQEQHVHNEKSVLKEVS- 105
Query: 342 LQHKNLVAMHDCMDSPAYVYVVMEYCNGGDLADYLQTNRLLSETTIQLFLAQLAEAMSAI 521
H L+ + ++Y++MEY GG+L YL+ S TT + A++ A+ +
Sbjct: 106 --HPFLIRLFWTWHDERFLYMLMEYVPGGELFSYLRNRGRFSSTTGLFYSAEIICAIEYL 163
Query: 522 HAKGIVHRDLKPQNILLTHSILPPRTPHPSDITLKIADFGFARFLEEGNMAVTLCGSPMY 701
H+K IV+RDLKP+NILL R H +K+ DFGFA+ L + TLCG+P Y
Sbjct: 164 HSKEIVYRDLKPENILL------DRDGH-----IKLTDFGFAKKLVDRTW--TLCGTPEY 210
Query: 702 MAPEVIMS 725
+APEVI S
Sbjct: 211 LAPEVIQS 218
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 107,800,470
Number of Sequences: 237096
Number of extensions: 2310281
Number of successful extensions: 11622
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 7807
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 8616
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8623170556
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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