Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmte29l11
(657 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X93209-2|CAA63698.1| 1151|Homo sapiens NRD1 convertase protein. 123 6e-28
X93207-2|CAA63694.1| 1219|Homo sapiens NRD2 convertase protein. 123 6e-28
U64898-1|AAC39597.1| 1147|Homo sapiens NRD convertase protein. 123 6e-28
BC008775-1|AAH08775.1| 1150|Homo sapiens NRD1 protein protein. 123 6e-28
AY360265-1|AAQ63406.1| 1086|Homo sapiens nardilysin isoform prot... 123 6e-28
AL589663-4|CAH74099.1| 1219|Homo sapiens nardilysin (N-arginine ... 123 6e-28
AL589663-3|CAH74100.1| 1151|Homo sapiens nardilysin (N-arginine ... 123 6e-28
AL050343-3|CAI22215.1| 1219|Homo sapiens nardilysin (N-arginine ... 123 6e-28
AL050343-2|CAI22216.1| 1151|Homo sapiens nardilysin (N-arginine ... 123 6e-28
AL050343-1|CAI22214.1| 537|Homo sapiens nardilysin (N-arginine ... 82 1e-15
AY049784-1|AAL15441.1| 948|Homo sapiens nardilysin protein. 71 3e-12
BC096339-1|AAH96339.1| 1019|Homo sapiens insulin-degrading enzym... 65 2e-10
BC096337-1|AAH96337.1| 1019|Homo sapiens insulin-degrading enzym... 65 2e-10
BC096336-1|AAH96336.1| 1019|Homo sapiens insulin-degrading enzym... 65 2e-10
AL356128-2|CAI13670.1| 1019|Homo sapiens insulin-degrading enzym... 65 2e-10
AB209204-1|BAD92441.1| 594|Homo sapiens insulysin variant protein. 65 2e-10
M21188-1|AAA52712.1| 1019|Homo sapiens insulin-degrading enzyme ... 62 1e-09
>X93209-2|CAA63698.1| 1151|Homo sapiens NRD1 convertase protein.
Length = 1151
Score = 123 bits (296), Expect = 6e-28
Identities = 73/220 (33%), Positives = 116/220 (52%), Gaps = 2/220 (0%)
Frame = +2
Query: 2 FEAVREVRARSYHNVLLKPNRLAKDLRMQVLLEPYISPRDK-AFVIHNITXXXXXXXXXX 178
F + E ++Y N+L+KP LAKD+R+ +L S DK ++ ++
Sbjct: 791 FTMITEQLKKTYFNILIKPETLAKDVRLLILEYARWSMIDKYQALMDGLSLESLLSFVKE 850
Query: 179 XXSKLYMQVLVQGNLAWYDAINISQNVFSNMQWESLSESEIP-QLQVHELPLGERKLRVM 355
S+L+++ LVQGN+ ++++ + V + ++ L E E+P Q QV ELP G +V
Sbjct: 851 FKSQLFVEGLVQGNVTSTESMDFLKYVVDKLNFKPL-EQEMPVQFQVVELPSGHHLCKVK 909
Query: 356 SLNEASTNSIITNYYQAEVTTPSDLAXXXXXXXXXXXXXFDMLRTKEQLGYSVFSMMRYT 535
+LN+ NS +T YYQ+ + + FD LRTK+ LGY V+ R T
Sbjct: 910 ALNKGDANSEVTVYYQSGTRSLREYTLMELLVMHMEEPCFDFLRTKQTLGYHVYPTCRNT 969
Query: 536 FGVLGFSVSVNTQVDKFSVSYVDGRVEAFLRKFYRDMKRL 655
G+LGFSV+V TQ K++ VD ++E FL F ++ L
Sbjct: 970 SGILGFSVTVGTQATKYNSEVVDKKIEEFLSSFEEKIENL 1009
>X93207-2|CAA63694.1| 1219|Homo sapiens NRD2 convertase protein.
Length = 1219
Score = 123 bits (296), Expect = 6e-28
Identities = 73/220 (33%), Positives = 116/220 (52%), Gaps = 2/220 (0%)
Frame = +2
Query: 2 FEAVREVRARSYHNVLLKPNRLAKDLRMQVLLEPYISPRDK-AFVIHNITXXXXXXXXXX 178
F + E ++Y N+L+KP LAKD+R+ +L S DK ++ ++
Sbjct: 859 FTMITEQLKKTYFNILIKPETLAKDVRLLILEYARWSMIDKYQALMDGLSLESLLSFVKE 918
Query: 179 XXSKLYMQVLVQGNLAWYDAINISQNVFSNMQWESLSESEIP-QLQVHELPLGERKLRVM 355
S+L+++ LVQGN+ ++++ + V + ++ L E E+P Q QV ELP G +V
Sbjct: 919 FKSQLFVEGLVQGNVTSTESMDFLKYVVDKLNFKPL-EQEMPVQFQVVELPSGHHLCKVK 977
Query: 356 SLNEASTNSIITNYYQAEVTTPSDLAXXXXXXXXXXXXXFDMLRTKEQLGYSVFSMMRYT 535
+LN+ NS +T YYQ+ + + FD LRTK+ LGY V+ R T
Sbjct: 978 ALNKGDANSEVTVYYQSGTRSLREYTLMELLVMHMEEPCFDFLRTKQTLGYHVYPTCRNT 1037
Query: 536 FGVLGFSVSVNTQVDKFSVSYVDGRVEAFLRKFYRDMKRL 655
G+LGFSV+V TQ K++ VD ++E FL F ++ L
Sbjct: 1038 SGILGFSVTVGTQATKYNSEVVDKKIEEFLSSFEEKIENL 1077
>U64898-1|AAC39597.1| 1147|Homo sapiens NRD convertase protein.
Length = 1147
Score = 123 bits (296), Expect = 6e-28
Identities = 73/220 (33%), Positives = 116/220 (52%), Gaps = 2/220 (0%)
Frame = +2
Query: 2 FEAVREVRARSYHNVLLKPNRLAKDLRMQVLLEPYISPRDK-AFVIHNITXXXXXXXXXX 178
F + E ++Y N+L+KP LAKD+R+ +L S DK ++ ++
Sbjct: 790 FTMITEQLKKTYFNILIKPETLAKDVRLLILEYARWSMIDKYQALMDGLSLESLLSFVKE 849
Query: 179 XXSKLYMQVLVQGNLAWYDAINISQNVFSNMQWESLSESEIP-QLQVHELPLGERKLRVM 355
S+L+++ LVQGN+ ++++ + V + ++ L E E+P Q QV ELP G +V
Sbjct: 850 FKSQLFVEGLVQGNVTSTESMDFLKYVVDKLNFKPL-EQEMPVQFQVVELPSGHHLCKVK 908
Query: 356 SLNEASTNSIITNYYQAEVTTPSDLAXXXXXXXXXXXXXFDMLRTKEQLGYSVFSMMRYT 535
+LN+ NS +T YYQ+ + + FD LRTK+ LGY V+ R T
Sbjct: 909 ALNKGDANSEVTVYYQSGTRSLREYTLMELLVMHMEEPCFDFLRTKQTLGYHVYPTCRNT 968
Query: 536 FGVLGFSVSVNTQVDKFSVSYVDGRVEAFLRKFYRDMKRL 655
G+LGFSV+V TQ K++ VD ++E FL F ++ L
Sbjct: 969 SGILGFSVTVGTQATKYNSEVVDKKIEEFLSSFEEKIENL 1008
>BC008775-1|AAH08775.1| 1150|Homo sapiens NRD1 protein protein.
Length = 1150
Score = 123 bits (296), Expect = 6e-28
Identities = 73/220 (33%), Positives = 116/220 (52%), Gaps = 2/220 (0%)
Frame = +2
Query: 2 FEAVREVRARSYHNVLLKPNRLAKDLRMQVLLEPYISPRDK-AFVIHNITXXXXXXXXXX 178
F + E ++Y N+L+KP LAKD+R+ +L S DK ++ ++
Sbjct: 790 FTMITEQLKKTYFNILIKPETLAKDVRLLILEYARWSMIDKYQALMDGLSLESLLSFVKE 849
Query: 179 XXSKLYMQVLVQGNLAWYDAINISQNVFSNMQWESLSESEIP-QLQVHELPLGERKLRVM 355
S+L+++ LVQGN+ ++++ + V + ++ L E E+P Q QV ELP G +V
Sbjct: 850 FKSQLFVEGLVQGNVTSTESMDFLKYVVDKLNFKPL-EQEMPVQFQVVELPSGHHLCKVK 908
Query: 356 SLNEASTNSIITNYYQAEVTTPSDLAXXXXXXXXXXXXXFDMLRTKEQLGYSVFSMMRYT 535
+LN+ NS +T YYQ+ + + FD LRTK+ LGY V+ R T
Sbjct: 909 ALNKGDANSEVTVYYQSGTRSLREYTLMELLVMHMEEPCFDFLRTKQTLGYHVYPTCRNT 968
Query: 536 FGVLGFSVSVNTQVDKFSVSYVDGRVEAFLRKFYRDMKRL 655
G+LGFSV+V TQ K++ VD ++E FL F ++ L
Sbjct: 969 SGILGFSVTVGTQATKYNSEVVDKKIEEFLSSFEEKIENL 1008
>AY360265-1|AAQ63406.1| 1086|Homo sapiens nardilysin isoform protein.
Length = 1086
Score = 123 bits (296), Expect = 6e-28
Identities = 73/220 (33%), Positives = 116/220 (52%), Gaps = 2/220 (0%)
Frame = +2
Query: 2 FEAVREVRARSYHNVLLKPNRLAKDLRMQVLLEPYISPRDK-AFVIHNITXXXXXXXXXX 178
F + E ++Y N+L+KP LAKD+R+ +L S DK ++ ++
Sbjct: 726 FTMITEQLKKTYFNILIKPETLAKDVRLLILEYARWSMIDKYQALMDGLSLESLLSFVKE 785
Query: 179 XXSKLYMQVLVQGNLAWYDAINISQNVFSNMQWESLSESEIP-QLQVHELPLGERKLRVM 355
S+L+++ LVQGN+ ++++ + V + ++ L E E+P Q QV ELP G +V
Sbjct: 786 FKSQLFVEGLVQGNVTSTESMDFLKYVVDKLNFKPL-EQEMPVQFQVVELPSGHHLCKVK 844
Query: 356 SLNEASTNSIITNYYQAEVTTPSDLAXXXXXXXXXXXXXFDMLRTKEQLGYSVFSMMRYT 535
+LN+ NS +T YYQ+ + + FD LRTK+ LGY V+ R T
Sbjct: 845 ALNKGDANSEVTVYYQSGTRSLREYTLMELLVMHMEEPCFDFLRTKQTLGYHVYPTCRNT 904
Query: 536 FGVLGFSVSVNTQVDKFSVSYVDGRVEAFLRKFYRDMKRL 655
G+LGFSV+V TQ K++ VD ++E FL F ++ L
Sbjct: 905 SGILGFSVTVGTQATKYNSEVVDKKIEEFLSSFEEKIENL 944
>AL589663-4|CAH74099.1| 1219|Homo sapiens nardilysin (N-arginine
dibasic convertase) protein.
Length = 1219
Score = 123 bits (296), Expect = 6e-28
Identities = 73/220 (33%), Positives = 116/220 (52%), Gaps = 2/220 (0%)
Frame = +2
Query: 2 FEAVREVRARSYHNVLLKPNRLAKDLRMQVLLEPYISPRDK-AFVIHNITXXXXXXXXXX 178
F + E ++Y N+L+KP LAKD+R+ +L S DK ++ ++
Sbjct: 859 FTMITEQLKKTYFNILIKPETLAKDVRLLILEYARWSMIDKYQALMDGLSLESLLSFVKE 918
Query: 179 XXSKLYMQVLVQGNLAWYDAINISQNVFSNMQWESLSESEIP-QLQVHELPLGERKLRVM 355
S+L+++ LVQGN+ ++++ + V + ++ L E E+P Q QV ELP G +V
Sbjct: 919 FKSQLFVEGLVQGNVTSTESMDFLKYVVDKLNFKPL-EQEMPVQFQVVELPSGHHLCKVK 977
Query: 356 SLNEASTNSIITNYYQAEVTTPSDLAXXXXXXXXXXXXXFDMLRTKEQLGYSVFSMMRYT 535
+LN+ NS +T YYQ+ + + FD LRTK+ LGY V+ R T
Sbjct: 978 ALNKGDANSEVTVYYQSGTRSLREYTLMELLVMHMEEPCFDFLRTKQTLGYHVYPTCRNT 1037
Query: 536 FGVLGFSVSVNTQVDKFSVSYVDGRVEAFLRKFYRDMKRL 655
G+LGFSV+V TQ K++ VD ++E FL F ++ L
Sbjct: 1038 SGILGFSVTVGTQATKYNSEVVDKKIEEFLSSFEEKIENL 1077
>AL589663-3|CAH74100.1| 1151|Homo sapiens nardilysin (N-arginine
dibasic convertase) protein.
Length = 1151
Score = 123 bits (296), Expect = 6e-28
Identities = 73/220 (33%), Positives = 116/220 (52%), Gaps = 2/220 (0%)
Frame = +2
Query: 2 FEAVREVRARSYHNVLLKPNRLAKDLRMQVLLEPYISPRDK-AFVIHNITXXXXXXXXXX 178
F + E ++Y N+L+KP LAKD+R+ +L S DK ++ ++
Sbjct: 791 FTMITEQLKKTYFNILIKPETLAKDVRLLILEYARWSMIDKYQALMDGLSLESLLSFVKE 850
Query: 179 XXSKLYMQVLVQGNLAWYDAINISQNVFSNMQWESLSESEIP-QLQVHELPLGERKLRVM 355
S+L+++ LVQGN+ ++++ + V + ++ L E E+P Q QV ELP G +V
Sbjct: 851 FKSQLFVEGLVQGNVTSTESMDFLKYVVDKLNFKPL-EQEMPVQFQVVELPSGHHLCKVK 909
Query: 356 SLNEASTNSIITNYYQAEVTTPSDLAXXXXXXXXXXXXXFDMLRTKEQLGYSVFSMMRYT 535
+LN+ NS +T YYQ+ + + FD LRTK+ LGY V+ R T
Sbjct: 910 ALNKGDANSEVTVYYQSGTRSLREYTLMELLVMHMEEPCFDFLRTKQTLGYHVYPTCRNT 969
Query: 536 FGVLGFSVSVNTQVDKFSVSYVDGRVEAFLRKFYRDMKRL 655
G+LGFSV+V TQ K++ VD ++E FL F ++ L
Sbjct: 970 SGILGFSVTVGTQATKYNSEVVDKKIEEFLSSFEEKIENL 1009
>AL050343-3|CAI22215.1| 1219|Homo sapiens nardilysin (N-arginine
dibasic convertase) protein.
Length = 1219
Score = 123 bits (296), Expect = 6e-28
Identities = 73/220 (33%), Positives = 116/220 (52%), Gaps = 2/220 (0%)
Frame = +2
Query: 2 FEAVREVRARSYHNVLLKPNRLAKDLRMQVLLEPYISPRDK-AFVIHNITXXXXXXXXXX 178
F + E ++Y N+L+KP LAKD+R+ +L S DK ++ ++
Sbjct: 859 FTMITEQLKKTYFNILIKPETLAKDVRLLILEYARWSMIDKYQALMDGLSLESLLSFVKE 918
Query: 179 XXSKLYMQVLVQGNLAWYDAINISQNVFSNMQWESLSESEIP-QLQVHELPLGERKLRVM 355
S+L+++ LVQGN+ ++++ + V + ++ L E E+P Q QV ELP G +V
Sbjct: 919 FKSQLFVEGLVQGNVTSTESMDFLKYVVDKLNFKPL-EQEMPVQFQVVELPSGHHLCKVK 977
Query: 356 SLNEASTNSIITNYYQAEVTTPSDLAXXXXXXXXXXXXXFDMLRTKEQLGYSVFSMMRYT 535
+LN+ NS +T YYQ+ + + FD LRTK+ LGY V+ R T
Sbjct: 978 ALNKGDANSEVTVYYQSGTRSLREYTLMELLVMHMEEPCFDFLRTKQTLGYHVYPTCRNT 1037
Query: 536 FGVLGFSVSVNTQVDKFSVSYVDGRVEAFLRKFYRDMKRL 655
G+LGFSV+V TQ K++ VD ++E FL F ++ L
Sbjct: 1038 SGILGFSVTVGTQATKYNSEVVDKKIEEFLSSFEEKIENL 1077
>AL050343-2|CAI22216.1| 1151|Homo sapiens nardilysin (N-arginine
dibasic convertase) protein.
Length = 1151
Score = 123 bits (296), Expect = 6e-28
Identities = 73/220 (33%), Positives = 116/220 (52%), Gaps = 2/220 (0%)
Frame = +2
Query: 2 FEAVREVRARSYHNVLLKPNRLAKDLRMQVLLEPYISPRDK-AFVIHNITXXXXXXXXXX 178
F + E ++Y N+L+KP LAKD+R+ +L S DK ++ ++
Sbjct: 791 FTMITEQLKKTYFNILIKPETLAKDVRLLILEYARWSMIDKYQALMDGLSLESLLSFVKE 850
Query: 179 XXSKLYMQVLVQGNLAWYDAINISQNVFSNMQWESLSESEIP-QLQVHELPLGERKLRVM 355
S+L+++ LVQGN+ ++++ + V + ++ L E E+P Q QV ELP G +V
Sbjct: 851 FKSQLFVEGLVQGNVTSTESMDFLKYVVDKLNFKPL-EQEMPVQFQVVELPSGHHLCKVK 909
Query: 356 SLNEASTNSIITNYYQAEVTTPSDLAXXXXXXXXXXXXXFDMLRTKEQLGYSVFSMMRYT 535
+LN+ NS +T YYQ+ + + FD LRTK+ LGY V+ R T
Sbjct: 910 ALNKGDANSEVTVYYQSGTRSLREYTLMELLVMHMEEPCFDFLRTKQTLGYHVYPTCRNT 969
Query: 536 FGVLGFSVSVNTQVDKFSVSYVDGRVEAFLRKFYRDMKRL 655
G+LGFSV+V TQ K++ VD ++E FL F ++ L
Sbjct: 970 SGILGFSVTVGTQATKYNSEVVDKKIEEFLSSFEEKIENL 1009
>AL050343-1|CAI22214.1| 537|Homo sapiens nardilysin (N-arginine
dibasic convertase) protein.
Length = 537
Score = 82.2 bits (194), Expect = 1e-15
Identities = 53/173 (30%), Positives = 87/173 (50%), Gaps = 2/173 (1%)
Frame = +2
Query: 2 FEAVREVRARSYHNVLLKPNRLAKDLRMQVLLEPYISPRDK-AFVIHNITXXXXXXXXXX 178
F + E ++Y N+L+KP LAKD+R+ +L S DK ++ ++
Sbjct: 205 FTMITEQLKKTYFNILIKPETLAKDVRLLILEYARWSMIDKYQALMDGLSLESLLSFVKE 264
Query: 179 XXSKLYMQVLVQGNLAWYDAINISQNVFSNMQWESLSESEIP-QLQVHELPLGERKLRVM 355
S+L+++ LVQGN+ ++++ + V + ++ L E E+P Q QV ELP G +V
Sbjct: 265 FKSQLFVEGLVQGNVTSTESMDFLKYVVDKLNFKPL-EQEMPVQFQVVELPSGHHLCKVK 323
Query: 356 SLNEASTNSIITNYYQAEVTTPSDLAXXXXXXXXXXXXXFDMLRTKEQLGYSV 514
+LN+ NS +T YYQ+ + + FD LRTK+ LG V
Sbjct: 324 ALNKGDANSEVTVYYQSGTRSLREYTLMELLVMHMEEPCFDFLRTKQTLGSEV 376
>AY049784-1|AAL15441.1| 948|Homo sapiens nardilysin protein.
Length = 948
Score = 71.3 bits (167), Expect = 3e-12
Identities = 44/136 (32%), Positives = 74/136 (54%), Gaps = 2/136 (1%)
Frame = +2
Query: 2 FEAVREVRARSYHNVLLKPNRLAKDLRMQVLLEPYISPRDK-AFVIHNITXXXXXXXXXX 178
F + E ++Y N+L+KP LAKD+R+ +L S DK ++ ++
Sbjct: 790 FTMITEQLKKTYFNILIKPETLAKDVRLLILEYARWSMIDKYQALMDGLSLESLLSFVKE 849
Query: 179 XXSKLYMQVLVQGNLAWYDAINISQNVFSNMQWESLSESEIP-QLQVHELPLGERKLRVM 355
S+L+++ LVQGN+ ++++ + V + ++ L E E+P Q QV ELP G +V
Sbjct: 850 FKSQLFVEGLVQGNVTSTESMDFLKYVVDKLNFKPL-EQEMPVQFQVVELPSGHHLCKVK 908
Query: 356 SLNEASTNSIITNYYQ 403
+LN+ NS +T YYQ
Sbjct: 909 ALNKGDANSEVTVYYQ 924
>BC096339-1|AAH96339.1| 1019|Homo sapiens insulin-degrading enzyme
protein.
Length = 1019
Score = 64.9 bits (151), Expect = 2e-10
Identities = 55/212 (25%), Positives = 95/212 (44%), Gaps = 4/212 (1%)
Frame = +2
Query: 2 FEAVREVRARSYHNVLLK-PNRLAKDLRMQVLLEPYISPRDKAFVIHNITXXXXXXXXXX 178
FE ++E RS +N + P++ A ++ E + + + ++T
Sbjct: 659 FEIIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQ 718
Query: 179 XXSKLYMQVLVQGNLAWYDAINISQNVFSNMQWESLSESEIPQ--LQVHELPLGERKLRV 352
S+L+++ L+ GN+ A+ I Q V + + ++ +P ++ E+ L +R V
Sbjct: 719 LLSRLHIEALLHGNITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFV 778
Query: 353 -MSLNEASTNSIITNYYQAEVTTPSDLAXXXXXXXXXXXXXFDMLRTKEQLGYSVFSMMR 529
NE N I YYQ ++ + S+ F+ LRTKEQLGY VFS R
Sbjct: 779 YQQRNEVHNNCGIEIYYQTDMQSTSENMFLELFCQIISEPCFNTLRTKEQLGYIVFSGPR 838
Query: 530 YTFGVLGFSVSVNTQVDKFSVSYVDGRVEAFL 625
G+ G + ++ Y++ RVEAFL
Sbjct: 839 RANGIQGLRFIIQSEKPP---HYLESRVEAFL 867
>BC096337-1|AAH96337.1| 1019|Homo sapiens insulin-degrading enzyme
protein.
Length = 1019
Score = 64.9 bits (151), Expect = 2e-10
Identities = 55/212 (25%), Positives = 95/212 (44%), Gaps = 4/212 (1%)
Frame = +2
Query: 2 FEAVREVRARSYHNVLLK-PNRLAKDLRMQVLLEPYISPRDKAFVIHNITXXXXXXXXXX 178
FE ++E RS +N + P++ A ++ E + + + ++T
Sbjct: 659 FEIIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQ 718
Query: 179 XXSKLYMQVLVQGNLAWYDAINISQNVFSNMQWESLSESEIPQ--LQVHELPLGERKLRV 352
S+L+++ L+ GN+ A+ I Q V + + ++ +P ++ E+ L +R V
Sbjct: 719 LLSRLHIEALLHGNITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFV 778
Query: 353 -MSLNEASTNSIITNYYQAEVTTPSDLAXXXXXXXXXXXXXFDMLRTKEQLGYSVFSMMR 529
NE N I YYQ ++ + S+ F+ LRTKEQLGY VFS R
Sbjct: 779 YQQRNEVHNNCGIEIYYQTDMQSTSENMFLELFCQIISEPCFNTLRTKEQLGYIVFSGPR 838
Query: 530 YTFGVLGFSVSVNTQVDKFSVSYVDGRVEAFL 625
G+ G + ++ Y++ RVEAFL
Sbjct: 839 RANGIQGLRFIIQSEKPP---HYLESRVEAFL 867
>BC096336-1|AAH96336.1| 1019|Homo sapiens insulin-degrading enzyme
protein.
Length = 1019
Score = 64.9 bits (151), Expect = 2e-10
Identities = 55/212 (25%), Positives = 95/212 (44%), Gaps = 4/212 (1%)
Frame = +2
Query: 2 FEAVREVRARSYHNVLLK-PNRLAKDLRMQVLLEPYISPRDKAFVIHNITXXXXXXXXXX 178
FE ++E RS +N + P++ A ++ E + + + ++T
Sbjct: 659 FEIIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQ 718
Query: 179 XXSKLYMQVLVQGNLAWYDAINISQNVFSNMQWESLSESEIPQ--LQVHELPLGERKLRV 352
S+L+++ L+ GN+ A+ I Q V + + ++ +P ++ E+ L +R V
Sbjct: 719 LLSRLHIEALLHGNITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFV 778
Query: 353 -MSLNEASTNSIITNYYQAEVTTPSDLAXXXXXXXXXXXXXFDMLRTKEQLGYSVFSMMR 529
NE N I YYQ ++ + S+ F+ LRTKEQLGY VFS R
Sbjct: 779 YQQRNEVHNNCGIEIYYQTDMQSTSENMFLELFCQIISEPCFNTLRTKEQLGYIVFSGPR 838
Query: 530 YTFGVLGFSVSVNTQVDKFSVSYVDGRVEAFL 625
G+ G + ++ Y++ RVEAFL
Sbjct: 839 RANGIQGLRFIIQSEKPP---HYLESRVEAFL 867
>AL356128-2|CAI13670.1| 1019|Homo sapiens insulin-degrading enzyme
protein.
Length = 1019
Score = 64.9 bits (151), Expect = 2e-10
Identities = 55/212 (25%), Positives = 95/212 (44%), Gaps = 4/212 (1%)
Frame = +2
Query: 2 FEAVREVRARSYHNVLLK-PNRLAKDLRMQVLLEPYISPRDKAFVIHNITXXXXXXXXXX 178
FE ++E RS +N + P++ A ++ E + + + ++T
Sbjct: 659 FEIIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQ 718
Query: 179 XXSKLYMQVLVQGNLAWYDAINISQNVFSNMQWESLSESEIPQ--LQVHELPLGERKLRV 352
S+L+++ L+ GN+ A+ I Q V + + ++ +P ++ E+ L +R V
Sbjct: 719 LLSRLHIEALLHGNITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFV 778
Query: 353 -MSLNEASTNSIITNYYQAEVTTPSDLAXXXXXXXXXXXXXFDMLRTKEQLGYSVFSMMR 529
NE N I YYQ ++ + S+ F+ LRTKEQLGY VFS R
Sbjct: 779 YQQRNEVHNNCGIEIYYQTDMQSTSENMFLELFCQIISEPCFNTLRTKEQLGYIVFSGPR 838
Query: 530 YTFGVLGFSVSVNTQVDKFSVSYVDGRVEAFL 625
G+ G + ++ Y++ RVEAFL
Sbjct: 839 RANGIQGLRFIIQSEKPP---HYLESRVEAFL 867
>AB209204-1|BAD92441.1| 594|Homo sapiens insulysin variant protein.
Length = 594
Score = 64.9 bits (151), Expect = 2e-10
Identities = 55/212 (25%), Positives = 95/212 (44%), Gaps = 4/212 (1%)
Frame = +2
Query: 2 FEAVREVRARSYHNVLLK-PNRLAKDLRMQVLLEPYISPRDKAFVIHNITXXXXXXXXXX 178
FE ++E RS +N + P++ A ++ E + + + ++T
Sbjct: 234 FEIIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQ 293
Query: 179 XXSKLYMQVLVQGNLAWYDAINISQNVFSNMQWESLSESEIPQ--LQVHELPLGERKLRV 352
S+L+++ L+ GN+ A+ I Q V + + ++ +P ++ E+ L +R V
Sbjct: 294 LLSRLHIEALLHGNITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFV 353
Query: 353 -MSLNEASTNSIITNYYQAEVTTPSDLAXXXXXXXXXXXXXFDMLRTKEQLGYSVFSMMR 529
NE N I YYQ ++ + S+ F+ LRTKEQLGY VFS R
Sbjct: 354 YQQRNEVHNNCGIEIYYQTDMQSTSENMFLELFCQIISEPCFNTLRTKEQLGYIVFSGPR 413
Query: 530 YTFGVLGFSVSVNTQVDKFSVSYVDGRVEAFL 625
G+ G + ++ Y++ RVEAFL
Sbjct: 414 RANGIQGLRFIIQSEKPP---HYLESRVEAFL 442
>M21188-1|AAA52712.1| 1019|Homo sapiens insulin-degrading enzyme
protein.
Length = 1019
Score = 62.5 bits (145), Expect = 1e-09
Identities = 54/212 (25%), Positives = 94/212 (44%), Gaps = 4/212 (1%)
Frame = +2
Query: 2 FEAVREVRARSYHNVLLK-PNRLAKDLRMQVLLEPYISPRDKAFVIHNITXXXXXXXXXX 178
FE ++E RS +N + P++ A ++ E + + + ++T
Sbjct: 659 FEIIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQ 718
Query: 179 XXSKLYMQVLVQGNLAWYDAINISQNVFSNMQWESLSESEIPQ--LQVHELPLGERKLRV 352
S+L+++ L+ GN+ A+ I Q V + + ++ +P ++ E+ L +R V
Sbjct: 719 LLSRLHIEALLHGNITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFV 778
Query: 353 -MSLNEASTNSIITNYYQAEVTTPSDLAXXXXXXXXXXXXXFDMLRTKEQLGYSVFSMMR 529
NE N I YYQ ++ + S+ F+ LRTKEQLGY VFS R
Sbjct: 779 YQQRNEVHNNCGIEIYYQTDMQSTSENMFLELFCQIISEPCFNTLRTKEQLGYIVFSGPR 838
Query: 530 YTFGVLGFSVSVNTQVDKFSVSYVDGRVEAFL 625
G+ + ++ Y++ RVEAFL
Sbjct: 839 RANGIQSLRFIIQSEKPP---HYLESRVEAFL 867
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 81,988,508
Number of Sequences: 237096
Number of extensions: 1478583
Number of successful extensions: 4015
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 3844
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3994
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7366354010
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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