Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmte26h24
(685 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxystero... 150 4e-36
U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol dehyd... 147 4e-35
U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase... 147 4e-35
M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase... 147 4e-35
BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase fam... 147 4e-35
BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase fam... 147 4e-35
BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase fam... 147 4e-35
BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase fam... 147 4e-35
AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase fam... 147 4e-35
AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid ... 147 4e-35
AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid d... 147 4e-35
AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid ... 147 4e-35
AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid... 147 4e-35
S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase pro... 146 5e-35
D26125-1|BAA05122.1| 321|Homo sapiens 3 alpha-hydroxysteroid/di... 146 5e-35
AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase fam... 146 5e-35
AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogena... 146 5e-35
AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogena... 146 5e-35
D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein. 146 6e-35
BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase fam... 146 6e-35
AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthas... 146 6e-35
AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein. 146 6e-35
BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase fam... 146 8e-35
BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase fam... 146 8e-35
BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase fam... 146 8e-35
AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase fam... 146 8e-35
S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase hom... 145 1e-34
S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase hom... 145 1e-34
L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid de... 145 1e-34
U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase... 144 3e-34
S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase hom... 144 3e-34
L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol dehydrogenase... 144 3e-34
BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase fam... 144 3e-34
BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase fam... 144 3e-34
BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase fam... 144 3e-34
AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase fam... 144 3e-34
AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase fam... 144 3e-34
AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase fam... 144 3e-34
AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding prote... 144 3e-34
AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding prote... 144 3e-34
AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding p... 144 3e-34
CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein. 143 5e-34
J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein. 143 6e-34
X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for ... 142 1e-33
M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein. 142 1e-33
M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose re... 142 1e-33
J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein. 142 1e-33
J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein. 142 1e-33
CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein. 142 1e-33
BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase fam... 142 1e-33
BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase fam... 142 1e-33
BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase fam... 142 1e-33
AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen HD-C... 142 1e-33
AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein. 142 1e-33
J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein. 140 3e-33
CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein. 140 3e-33
BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase fam... 140 3e-33
BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase fam... 140 3e-33
BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase fam... 140 3e-33
AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase fam... 140 3e-33
AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase prot... 140 3e-33
AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase prot... 140 3e-33
AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase fam... 139 1e-32
D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase... 138 2e-32
BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase fam... 136 5e-32
M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordeco... 135 1e-31
Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5 be... 126 1e-28
BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase fam... 126 1e-28
BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase fam... 126 1e-28
AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductas... 126 1e-28
U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like pep... 122 2e-27
CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein. 122 2e-27
BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase fam... 122 2e-27
BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase fam... 122 2e-27
AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase pro... 122 2e-27
AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase prot... 117 3e-26
AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase loo... 72 6e-25
BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein. 72 6e-25
AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase rel... 72 6e-25
AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase fam... 105 1e-22
AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase rel... 72 2e-21
AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase rel... 72 2e-21
AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase fam... 88 2e-17
AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto red... 84 5e-16
AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase fam... 75 3e-13
AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase fam... 75 3e-13
AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase rel... 72 2e-12
BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase fam... 67 5e-11
BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase fam... 67 5e-11
AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens ... 67 5e-11
AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens ... 59 2e-08
AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthas... 57 7e-08
U16953-1|AAC50122.1| 408|Homo sapiens potassium channel beta3 s... 46 9e-05
L39833-1|AAC37573.1| 408|Homo sapiens K+ channel beta-subunit p... 46 9e-05
X83127-1|CAA58208.1| 401|Homo sapiens voltage gated potassium c... 46 2e-04
U33428-1|AAC50953.1| 401|Homo sapiens K+ channel beta 1a subuni... 46 2e-04
L47665-1|AAC41926.1| 419|Homo sapiens K+ channel beta-subunit p... 46 2e-04
BC043166-1|AAH43166.1| 401|Homo sapiens potassium voltage-gated... 46 2e-04
AF026947-1|AAC52104.1| 330|Homo sapiens aflatoxin aldehyde redu... 40 0.011
Y16675-1|CAA76347.1| 330|Homo sapiens aflatoxin B1-aldehyde red... 39 0.019
BT007347-1|AAP36011.1| 330|Homo sapiens aldo-keto reductase fam... 39 0.019
BC013996-1|AAH13996.1| 330|Homo sapiens AKR7A2 protein protein. 39 0.019
BC012171-1|AAH12171.1| 330|Homo sapiens AKR7A2 protein protein. 39 0.019
BC011586-1|AAH11586.1| 330|Homo sapiens AKR7A2 protein protein. 39 0.019
BC010852-1|AAH10852.1| 330|Homo sapiens AKR7A2 protein protein. 39 0.019
BC007352-1|AAH07352.2| 358|Homo sapiens AKR7A2 protein protein. 39 0.019
BC004111-1|AAH04111.3| 330|Homo sapiens AKR7A2 protein protein. 39 0.019
AL035413-8|CAB72321.1| 330|Homo sapiens aldo-keto reductase fam... 39 0.019
AB037905-2|BAA92890.1| 45|Homo sapiens truncated aldo-keto red... 39 0.019
AY780786-1|AAV98356.1| 372|Homo sapiens potassium voltage-gated... 37 0.077
BC042420-1|AAH42420.2| 331|Homo sapiens aldo-keto reductase fam... 35 0.31
BC031562-1|AAH31562.1| 331|Homo sapiens aldo-keto reductase fam... 35 0.31
AJ271799-1|CAC81076.1| 331|Homo sapiens aflatoxin B1 aldehyde r... 35 0.31
AF040639-1|AAD02195.1| 331|Homo sapiens aflatoxin B1-aldehyde r... 35 0.31
BC025709-1|AAH25709.1| 331|Homo sapiens aldo-keto reductase fam... 34 0.41
AL035413-11|CAI22232.1| 331|Homo sapiens aldo-keto reductase fa... 34 0.41
BX537840-1|CAD97851.1| 2150|Homo sapiens hypothetical protein pr... 32 1.7
BC040523-1|AAH40523.1| 1551|Homo sapiens CCR4-NOT transcription ... 32 1.7
BC024317-1|AAH24317.1| 1620|Homo sapiens CNOT1 protein protein. 32 1.7
AB023224-1|BAA76851.2| 1835|Homo sapiens KIAA1007 protein protein. 32 1.7
AM079206-1|CAL03352.1| 101|Homo sapiens immunoglobulin heavy ch... 32 2.2
AJ278012-1|CAC79668.1| 259|Homo sapiens aflatoxin B1 aldehyde r... 30 6.7
AF471315-1|AAQ05490.1| 128|Homo sapiens Ig heavy chain variable... 30 6.7
Y13790-1|CAA74116.1| 123|Homo sapiens immunoglobulin heavy chai... 30 8.8
U17968-1|AAC50113.1| 133|Homo sapiens voltage-gated potassium c... 30 8.8
AM082400-1|CAL06546.1| 101|Homo sapiens immunoglobulin heavy ch... 30 8.8
AM079381-1|CAL03527.1| 100|Homo sapiens immunoglobulin heavy ch... 30 8.8
AB066933-1|BAC01971.1| 129|Homo sapiens immunoglobulin heavy ch... 30 8.8
>DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 150 bits (364), Expect = 4e-36
Identities = 90/213 (42%), Positives = 130/213 (61%), Gaps = 18/213 (8%)
Frame = +2
Query: 101 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 280
+ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY NE+Q+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQV 61
Query: 281 GAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHNPVA 442
G AVR+ + REDIF +KL ++ R ++V+ LE+SL + + YVDLYLIH+P++
Sbjct: 62 GLAVRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKKAQLDYVDLYLIHSPMS 121
Query: 443 FNPGFK-------G---FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG- 589
PG + G FDIVD TW+ ME+ K+ GLAKSIG+SNFN Q++ IL
Sbjct: 122 LKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
Query: 590 -QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVM 685
+ KP QVE + + + KL+D+CK IV++
Sbjct: 182 LKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLV 214
>U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol
dehydrogenase protein.
Length = 323
Score = 147 bits (356), Expect = 4e-35
Identities = 89/213 (41%), Positives = 127/213 (59%), Gaps = 18/213 (8%)
Frame = +2
Query: 101 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 280
+ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY NE+Q+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQV 61
Query: 281 GAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHNPVA 442
G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH PV+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 443 FNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG- 589
PG + FD VD TW+ +E+ K+ GLAKSIG+SNFN Q++ IL
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
Query: 590 -QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVM 685
+ KP QVE + + Q KL+D+CK IV++
Sbjct: 182 LKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLV 214
>U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 147 bits (356), Expect = 4e-35
Identities = 89/213 (41%), Positives = 127/213 (59%), Gaps = 18/213 (8%)
Frame = +2
Query: 101 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 280
+ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY NE+Q+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQV 61
Query: 281 GAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHNPVA 442
G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH PV+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 443 FNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG- 589
PG + FD VD TW+ +E+ K+ GLAKSIG+SNFN Q++ IL
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
Query: 590 -QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVM 685
+ KP QVE + + Q KL+D+CK IV++
Sbjct: 182 LKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLV 214
>M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 147 bits (356), Expect = 4e-35
Identities = 89/213 (41%), Positives = 127/213 (59%), Gaps = 18/213 (8%)
Frame = +2
Query: 101 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 280
+ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY NE+Q+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQV 61
Query: 281 GAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHNPVA 442
G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH PV+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 443 FNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG- 589
PG + FD VD TW+ +E+ K+ GLAKSIG+SNFN Q++ IL
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
Query: 590 -QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVM 685
+ KP QVE + + Q KL+D+CK IV++
Sbjct: 182 LKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLV 214
>BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 147 bits (356), Expect = 4e-35
Identities = 89/213 (41%), Positives = 127/213 (59%), Gaps = 18/213 (8%)
Frame = +2
Query: 101 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 280
+ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY NE+Q+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQV 61
Query: 281 GAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHNPVA 442
G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH PV+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 443 FNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG- 589
PG + FD VD TW+ +E+ K+ GLAKSIG+SNFN Q++ IL
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
Query: 590 -QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVM 685
+ KP QVE + + Q KL+D+CK IV++
Sbjct: 182 LKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLV 214
>BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 147 bits (356), Expect = 4e-35
Identities = 89/213 (41%), Positives = 127/213 (59%), Gaps = 18/213 (8%)
Frame = +2
Query: 101 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 280
+ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY NE+Q+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQV 61
Query: 281 GAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHNPVA 442
G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH PV+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 443 FNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG- 589
PG + FD VD TW+ +E+ K+ GLAKSIG+SNFN Q++ IL
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
Query: 590 -QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVM 685
+ KP QVE + + Q KL+D+CK IV++
Sbjct: 182 LKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLV 214
>BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 147 bits (356), Expect = 4e-35
Identities = 89/213 (41%), Positives = 127/213 (59%), Gaps = 18/213 (8%)
Frame = +2
Query: 101 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 280
+ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY NE+Q+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQV 61
Query: 281 GAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHNPVA 442
G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH PV+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 443 FNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG- 589
PG + FD VD TW+ +E+ K+ GLAKSIG+SNFN Q++ IL
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
Query: 590 -QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVM 685
+ KP QVE + + Q KL+D+CK IV++
Sbjct: 182 LKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLV 214
>BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 147 bits (356), Expect = 4e-35
Identities = 89/213 (41%), Positives = 127/213 (59%), Gaps = 18/213 (8%)
Frame = +2
Query: 101 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 280
+ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY NE+Q+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQV 61
Query: 281 GAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHNPVA 442
G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH PV+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 443 FNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG- 589
PG + FD VD TW+ +E+ K+ GLAKSIG+SNFN Q++ IL
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
Query: 590 -QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVM 685
+ KP QVE + + Q KL+D+CK IV++
Sbjct: 182 LKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLV 214
>AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 147 bits (356), Expect = 4e-35
Identities = 89/213 (41%), Positives = 127/213 (59%), Gaps = 18/213 (8%)
Frame = +2
Query: 101 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 280
+ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY NE+Q+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQV 61
Query: 281 GAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHNPVA 442
G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH PV+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 443 FNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG- 589
PG + FD VD TW+ +E+ K+ GLAKSIG+SNFN Q++ IL
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
Query: 590 -QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVM 685
+ KP QVE + + Q KL+D+CK IV++
Sbjct: 182 LKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLV 214
>AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid
dehydrogenase type IIb protein.
Length = 323
Score = 147 bits (356), Expect = 4e-35
Identities = 90/217 (41%), Positives = 129/217 (59%), Gaps = 18/217 (8%)
Frame = +2
Query: 89 KASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN 268
K + LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY N
Sbjct: 4 KQQCVKLNDGHFMPVLGFGTY------APPEVPRSKALEVSKLAIEAGFRHIDSAHLYNN 57
Query: 269 EDQIGAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIH 430
E+Q+G A+R+ + REDIF +KL + R ++V+ LE SL + + YVDLYLIH
Sbjct: 58 EEQVGLAIRSKIADGSVKREDIFYTSKLWSTSHRPELVRPALENSLKKAQLDYVDLYLIH 117
Query: 431 NPVAFNPGFK-------G---FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL 580
+P++ PG + G FDIVD TW+ ME+ K+ GLAKSIG+SNFN Q++ IL
Sbjct: 118 SPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMIL 177
Query: 581 ENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVM 685
+ KP QVE + + + KL+D+CK IV++
Sbjct: 178 NKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLV 214
>AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 147 bits (356), Expect = 4e-35
Identities = 90/217 (41%), Positives = 124/217 (57%), Gaps = 18/217 (8%)
Frame = +2
Query: 89 KASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN 268
K ++ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY N
Sbjct: 4 KYQRVELNDGHFMPVLGFGTY------APPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNN 57
Query: 269 EDQIGAAVRAS----GIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIH 430
E+Q+G A+R+ + REDIF +KL + V LE SL +L + YVDLYL+H
Sbjct: 58 EEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLH 117
Query: 431 NPVAFNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL 580
P+A PG FD VD TW+ ME+ K+ GLAKSIG+SNFN Q++ IL
Sbjct: 118 FPMALKPGETPLPKDENGKVIFDTVDLCATWEVMEKCKDAGLAKSIGVSNFNCRQLEMIL 177
Query: 581 ENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVM 685
+ KP QVE + +L Q KL+D+CK IV++
Sbjct: 178 NKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLV 214
>AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 147 bits (356), Expect = 4e-35
Identities = 89/213 (41%), Positives = 127/213 (59%), Gaps = 18/213 (8%)
Frame = +2
Query: 101 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 280
+ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY NE+Q+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQV 61
Query: 281 GAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHNPVA 442
G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH PV+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 443 FNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG- 589
PG + FD VD TW+ +E+ K+ GLAKSIG+SNFN Q++ IL
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
Query: 590 -QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVM 685
+ KP QVE + + Q KL+D+CK IV++
Sbjct: 182 LKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLV 214
>AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 147 bits (356), Expect = 4e-35
Identities = 89/213 (41%), Positives = 127/213 (59%), Gaps = 18/213 (8%)
Frame = +2
Query: 101 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 280
+ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY NE+Q+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQV 61
Query: 281 GAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHNPVA 442
G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH PV+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 443 FNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG- 589
PG + FD VD TW+ +E+ K+ GLAKSIG+SNFN Q++ IL
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
Query: 590 -QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVM 685
+ KP QVE + + Q KL+D+CK IV++
Sbjct: 182 LKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLV 214
>S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase
protein.
Length = 323
Score = 146 bits (355), Expect = 5e-35
Identities = 90/217 (41%), Positives = 124/217 (57%), Gaps = 18/217 (8%)
Frame = +2
Query: 89 KASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN 268
K ++ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY N
Sbjct: 4 KYQRVELNDGHFMPVLGFGTY------APPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNN 57
Query: 269 EDQIGAAVRAS----GIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIH 430
E+Q+G A+R+ + REDIF +KL + V LE SL +L + YVDLYL+H
Sbjct: 58 EEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLH 117
Query: 431 NPVAFNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL 580
P+A PG FD VD TW+ ME+ K+ GLAKSIG+SNFN Q++ IL
Sbjct: 118 FPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMIL 177
Query: 581 ENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVM 685
+ KP QVE + +L Q KL+D+CK IV++
Sbjct: 178 NKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLV 214
>D26125-1|BAA05122.1| 321|Homo sapiens 3
alpha-hydroxysteroid/dihydrodiol dehydrogenase DD4
protein.
Length = 321
Score = 146 bits (355), Expect = 5e-35
Identities = 90/217 (41%), Positives = 124/217 (57%), Gaps = 18/217 (8%)
Frame = +2
Query: 89 KASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN 268
K ++ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY N
Sbjct: 2 KYQRVELNDGHFMPVLGFGTY------APPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNN 55
Query: 269 EDQIGAAVRAS----GIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIH 430
E+Q+G A+R+ + REDIF +KL + V LE SL +L + YVDLYL+H
Sbjct: 56 EEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLH 115
Query: 431 NPVAFNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL 580
P+A PG FD VD TW+ ME+ K+ GLAKSIG+SNFN Q++ IL
Sbjct: 116 FPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMIL 175
Query: 581 ENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVM 685
+ KP QVE + +L Q KL+D+CK IV++
Sbjct: 176 NKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLV 212
>AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 146 bits (355), Expect = 5e-35
Identities = 90/217 (41%), Positives = 124/217 (57%), Gaps = 18/217 (8%)
Frame = +2
Query: 89 KASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN 268
K ++ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY N
Sbjct: 4 KYQRVELNDGHFMPVLGFGTY------APPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNN 57
Query: 269 EDQIGAAVRAS----GIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIH 430
E+Q+G A+R+ + REDIF +KL + V LE SL +L + YVDLYL+H
Sbjct: 58 EEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLH 117
Query: 431 NPVAFNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL 580
P+A PG FD VD TW+ ME+ K+ GLAKSIG+SNFN Q++ IL
Sbjct: 118 FPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMIL 177
Query: 581 ENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVM 685
+ KP QVE + +L Q KL+D+CK IV++
Sbjct: 178 NKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLV 214
>AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 146 bits (355), Expect = 5e-35
Identities = 90/217 (41%), Positives = 124/217 (57%), Gaps = 18/217 (8%)
Frame = +2
Query: 89 KASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN 268
K ++ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY N
Sbjct: 4 KYQRVELNDGHFMPVLGFGTY------APPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNN 57
Query: 269 EDQIGAAVRAS----GIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIH 430
E+Q+G A+R+ + REDIF +KL + V LE SL +L + YVDLYL+H
Sbjct: 58 EEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLH 117
Query: 431 NPVAFNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL 580
P+A PG FD VD TW+ ME+ K+ GLAKSIG+SNFN Q++ IL
Sbjct: 118 FPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMIL 177
Query: 581 ENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVM 685
+ KP QVE + +L Q KL+D+CK IV++
Sbjct: 178 NKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLV 214
>AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 146 bits (355), Expect = 5e-35
Identities = 90/217 (41%), Positives = 124/217 (57%), Gaps = 18/217 (8%)
Frame = +2
Query: 89 KASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN 268
K ++ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY N
Sbjct: 4 KYQRVELNDGHFMPVLGFGTY------APPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNN 57
Query: 269 EDQIGAAVRAS----GIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIH 430
E+Q+G A+R+ + REDIF +KL + V LE SL +L + YVDLYL+H
Sbjct: 58 EEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLH 117
Query: 431 NPVAFNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL 580
P+A PG FD VD TW+ ME+ K+ GLAKSIG+SNFN Q++ IL
Sbjct: 118 FPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMIL 177
Query: 581 ENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVM 685
+ KP QVE + +L Q KL+D+CK IV++
Sbjct: 178 NKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLV 214
>D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein.
Length = 325
Score = 146 bits (354), Expect = 6e-35
Identities = 90/217 (41%), Positives = 128/217 (58%), Gaps = 18/217 (8%)
Frame = +2
Query: 89 KASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN 268
K + LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY N
Sbjct: 6 KQQCVKLNDGHFMPVLGFGTY------APPEVPRSKALEVTKLAIEAGFRHIDSAHLYNN 59
Query: 269 EDQIGAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIH 430
E+Q+G A+R+ + REDIF +KL R ++V+ LE SL + + YVDLYLIH
Sbjct: 60 EEQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIH 119
Query: 431 NPVAFNPGFK-------G---FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL 580
+P++ PG + G FDIVD TW+ ME+ K+ GLAKSIG+SNFN Q++ IL
Sbjct: 120 SPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMIL 179
Query: 581 ENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVM 685
+ KP QVE + + + KL+D+CK IV++
Sbjct: 180 NKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLV 216
>BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 146 bits (354), Expect = 6e-35
Identities = 90/217 (41%), Positives = 124/217 (57%), Gaps = 18/217 (8%)
Frame = +2
Query: 89 KASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN 268
K ++ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY N
Sbjct: 4 KYQRVELNDGHFMPVLGFGTY------APPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNN 57
Query: 269 EDQIGAAVRAS----GIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIH 430
E+Q+G A+R+ + REDIF +KL + V LE SL +L + YVDLYL+H
Sbjct: 58 EEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLH 117
Query: 431 NPVAFNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL 580
P+A PG FD VD TW+ ME+ K+ GLAKSIG+SNFN Q++ IL
Sbjct: 118 FPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNYRQLEMIL 177
Query: 581 ENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVM 685
+ KP QVE + +L Q KL+D+CK IV++
Sbjct: 178 NKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLV 214
>AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthase
protein.
Length = 323
Score = 146 bits (354), Expect = 6e-35
Identities = 90/217 (41%), Positives = 128/217 (58%), Gaps = 18/217 (8%)
Frame = +2
Query: 89 KASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN 268
K + LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY N
Sbjct: 4 KQQCVKLNDGHFMPVLGFGTY------APPEVPRSKALEVTKLAIEAGFRHIDSAHLYNN 57
Query: 269 EDQIGAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIH 430
E+Q+G A+R+ + REDIF +KL R ++V+ LE SL + + YVDLYLIH
Sbjct: 58 EEQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIH 117
Query: 431 NPVAFNPGFK-------G---FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL 580
+P++ PG + G FDIVD TW+ ME+ K+ GLAKSIG+SNFN Q++ IL
Sbjct: 118 SPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMIL 177
Query: 581 ENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVM 685
+ KP QVE + + + KL+D+CK IV++
Sbjct: 178 NKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLV 214
>AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein.
Length = 323
Score = 146 bits (354), Expect = 6e-35
Identities = 90/217 (41%), Positives = 128/217 (58%), Gaps = 18/217 (8%)
Frame = +2
Query: 89 KASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN 268
K + LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY N
Sbjct: 4 KQQCVKLNDGHFMPVLGFGTY------APPEVPRSKALEVTKLAIEAGFRHIDSAHLYNN 57
Query: 269 EDQIGAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIH 430
E+Q+G A+R+ + REDIF +KL R ++V+ LE SL + + YVDLYLIH
Sbjct: 58 EEQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIH 117
Query: 431 NPVAFNPGFK-------G---FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL 580
+P++ PG + G FDIVD TW+ ME+ K+ GLAKSIG+SNFN Q++ IL
Sbjct: 118 SPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMIL 177
Query: 581 ENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVM 685
+ KP QVE + + + KL+D+CK IV++
Sbjct: 178 NKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLV 214
>BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 146 bits (353), Expect = 8e-35
Identities = 89/213 (41%), Positives = 127/213 (59%), Gaps = 18/213 (8%)
Frame = +2
Query: 101 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 280
+ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY NE+Q+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQV 61
Query: 281 GAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHNPVA 442
G A+R+ + REDIF +KL R ++V+ LE SL + + YVDLYLIH+P++
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMS 121
Query: 443 FNPGFK-------G---FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG- 589
PG + G FDIVD TW+ ME+ K+ GLAKSIG+SNFN Q++ IL
Sbjct: 122 LKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
Query: 590 -QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVM 685
+ KP QVE + + + KL+D+CK IV++
Sbjct: 182 LKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLV 214
>BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 146 bits (353), Expect = 8e-35
Identities = 89/213 (41%), Positives = 127/213 (59%), Gaps = 18/213 (8%)
Frame = +2
Query: 101 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 280
+ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY NE+Q+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQV 61
Query: 281 GAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHNPVA 442
G A+R+ + REDIF +KL R ++V+ LE SL + + YVDLYLIH+P++
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMS 121
Query: 443 FNPGFK-------G---FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG- 589
PG + G FDIVD TW+ ME+ K+ GLAKSIG+SNFN Q++ IL
Sbjct: 122 LKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
Query: 590 -QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVM 685
+ KP QVE + + + KL+D+CK IV++
Sbjct: 182 LKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLV 214
>BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 146 bits (353), Expect = 8e-35
Identities = 89/213 (41%), Positives = 127/213 (59%), Gaps = 18/213 (8%)
Frame = +2
Query: 101 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 280
+ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY NE+Q+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQV 61
Query: 281 GAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHNPVA 442
G A+R+ + REDIF +KL R ++V+ LE SL + + YVDLYLIH+P++
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMS 121
Query: 443 FNPGFK-------G---FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG- 589
PG + G FDIVD TW+ ME+ K+ GLAKSIG+SNFN Q++ IL
Sbjct: 122 LKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
Query: 590 -QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVM 685
+ KP QVE + + + KL+D+CK IV++
Sbjct: 182 LKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLV 214
>AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 146 bits (353), Expect = 8e-35
Identities = 89/213 (41%), Positives = 127/213 (59%), Gaps = 18/213 (8%)
Frame = +2
Query: 101 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 280
+ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY NE+Q+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQV 61
Query: 281 GAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHNPVA 442
G A+R+ + REDIF +KL R ++V+ LE SL + + YVDLYLIH+P++
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMS 121
Query: 443 FNPGFK-------G---FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG- 589
PG + G FDIVD TW+ ME+ K+ GLAKSIG+SNFN Q++ IL
Sbjct: 122 LKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
Query: 590 -QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVM 685
+ KP QVE + + + KL+D+CK IV++
Sbjct: 182 LKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLV 214
>S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 145 bits (352), Expect = 1e-34
Identities = 90/217 (41%), Positives = 128/217 (58%), Gaps = 18/217 (8%)
Frame = +2
Query: 89 KASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN 268
K + LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY N
Sbjct: 4 KQQCVKLNDGHFMPVLGFGTY------APPEVPRSKALEVTKLAIEAGFRHIDSAHLYNN 57
Query: 269 EDQIGAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIH 430
E+Q+G A+R+ + REDIF +KL R ++V+ LE SL + + YVDLYLIH
Sbjct: 58 EEQVGLAIRSKIADGSVEREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIH 117
Query: 431 NPVAFNPGFK-------G---FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL 580
+P++ PG + G FDIVD TW+ ME+ K+ GLAKSIG+SNFN Q++ IL
Sbjct: 118 SPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEIIL 177
Query: 581 ENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVM 685
+ KP QVE + + + KL+D+CK IV++
Sbjct: 178 NKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLV 214
>S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase
homolog protein.
Length = 320
Score = 145 bits (351), Expect = 1e-34
Identities = 87/213 (40%), Positives = 125/213 (58%), Gaps = 18/213 (8%)
Frame = +2
Query: 101 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 280
+ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY NE+Q+
Sbjct: 5 VKLNDGHFMPVLGFGTY------APAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQV 58
Query: 281 GAAVRAS----GIPREDIFIVTKLPMDNQRDVVKQ--LEKSLARLNMSYVDLYLIHNPVA 442
G A+R+ + REDIF +KL ++ R + + LE+SL L + YVDLYLIH PV+
Sbjct: 59 GLAIRSKIADGSVKREDIFYTSKLWCNSHRPELDRPALERSLKNLQLDYVDLYLIHFPVS 118
Query: 443 FNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG- 589
PG + FD VD TW+ +E+ K+ LAKSIG+SNFN + ++ IL
Sbjct: 119 VKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAELAKSIGVSNFNRSTLEMILNKPG 178
Query: 590 -QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVM 685
Q+KP QVE + + Q KL+D+CK IV++
Sbjct: 179 LQVKPVCNQVECHPYFNQRKLLDFCKSKDIVLV 211
>L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 145 bits (351), Expect = 1e-34
Identities = 90/217 (41%), Positives = 128/217 (58%), Gaps = 18/217 (8%)
Frame = +2
Query: 89 KASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN 268
K + LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY N
Sbjct: 4 KQQCVKLNDGHFMPVLGFGTY------APPEVPRSKALEVTKLAIEAGFRHIDSAHLYNN 57
Query: 269 EDQIGAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIH 430
E+Q+G A+R+ + REDIF +KL R ++V+ LE SL + + YVDLYLIH
Sbjct: 58 EEQVGLAIRSKIADGSVMREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIH 117
Query: 431 NPVAFNPGFK-------G---FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL 580
+P++ PG + G FDIVD TW+ ME+ K+ GLAKSIG+SNFN Q++ IL
Sbjct: 118 SPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEIIL 177
Query: 581 ENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVM 685
+ KP QVE + + + KL+D+CK IV++
Sbjct: 178 NKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLV 214
>U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 144 bits (348), Expect = 3e-34
Identities = 88/213 (41%), Positives = 126/213 (59%), Gaps = 18/213 (8%)
Frame = +2
Query: 101 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 280
+ LNDG+ +P LG GT+ EV + + VK A+EAG+ ID+A +Y NE+Q+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQV 61
Query: 281 GAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHNPVA 442
G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH PV+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 443 FNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG- 589
PG + FD VD TW+ ME+ K+ GLAKSIG+SNFN ++ IL
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPG 181
Query: 590 -QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVM 685
+ KP QVE + + Q KL+D+CK IV++
Sbjct: 182 LKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLV 214
>S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 144 bits (348), Expect = 3e-34
Identities = 88/213 (41%), Positives = 126/213 (59%), Gaps = 18/213 (8%)
Frame = +2
Query: 101 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 280
+ LNDG+ +P LG GT+ EV + + VK A+EAG+ ID+A +Y NE+Q+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQV 61
Query: 281 GAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHNPVA 442
G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH PV+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 443 FNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQ 592
PG + FD VD TW+ ME+ K+ GLAKSIG+SNFN ++ IL
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNEPG 181
Query: 593 IK--PSVLQVEVNLHLGQDKLIDYCKRNGIVVM 685
+K P QVE + + Q KL+D+CK IV++
Sbjct: 182 LKYEPVCNQVECHPYFNQRKLLDFCKSKDIVLV 214
>L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol
dehydrogenase/bile acid-binding protein protein.
Length = 323
Score = 144 bits (348), Expect = 3e-34
Identities = 88/213 (41%), Positives = 125/213 (58%), Gaps = 18/213 (8%)
Frame = +2
Query: 101 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 280
+ LNDG+ +P LG GT+ EV + + VK A+EAGY ID+A +Y NE+Q+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEAVKLAIEAGYHHIDSAHVYNNEEQV 61
Query: 281 GAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHNPVA 442
G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + Y DLYLIH PV+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYADLYLIHFPVS 121
Query: 443 FNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQ 592
PG + FD VD TW+ ME+ K+ GLAKSIG+SNFN ++ IL
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNEPG 181
Query: 593 IK--PSVLQVEVNLHLGQDKLIDYCKRNGIVVM 685
+K P QVE + + Q KL+D+CK IV++
Sbjct: 182 LKYEPVCNQVECHPYFNQRKLLDFCKSKDIVLV 214
>BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 144 bits (348), Expect = 3e-34
Identities = 88/213 (41%), Positives = 126/213 (59%), Gaps = 18/213 (8%)
Frame = +2
Query: 101 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 280
+ LNDG+ +P LG GT+ EV + + VK A+EAG+ ID+A +Y NE+Q+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQV 61
Query: 281 GAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHNPVA 442
G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH PV+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 443 FNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG- 589
PG + FD VD TW+ ME+ K+ GLAKSIG+SNFN ++ IL
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPG 181
Query: 590 -QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVM 685
+ KP QVE + + Q KL+D+CK IV++
Sbjct: 182 LKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLV 214
>BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 144 bits (348), Expect = 3e-34
Identities = 88/213 (41%), Positives = 126/213 (59%), Gaps = 18/213 (8%)
Frame = +2
Query: 101 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 280
+ LNDG+ +P LG GT+ EV + + VK A+EAG+ ID+A +Y NE+Q+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQV 61
Query: 281 GAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHNPVA 442
G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH PV+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 443 FNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG- 589
PG + FD VD TW+ ME+ K+ GLAKSIG+SNFN ++ IL
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPG 181
Query: 590 -QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVM 685
+ KP QVE + + Q KL+D+CK IV++
Sbjct: 182 LKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLV 214
>BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 144 bits (348), Expect = 3e-34
Identities = 88/213 (41%), Positives = 126/213 (59%), Gaps = 18/213 (8%)
Frame = +2
Query: 101 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 280
+ LNDG+ +P LG GT+ EV + + VK A+EAG+ ID+A +Y NE+Q+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQV 61
Query: 281 GAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHNPVA 442
G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH PV+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 443 FNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG- 589
PG + FD VD TW+ ME+ K+ GLAKSIG+SNFN ++ IL
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPG 181
Query: 590 -QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVM 685
+ KP QVE + + Q KL+D+CK IV++
Sbjct: 182 LKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLV 214
>AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 144 bits (348), Expect = 3e-34
Identities = 88/213 (41%), Positives = 126/213 (59%), Gaps = 18/213 (8%)
Frame = +2
Query: 101 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 280
+ LNDG+ +P LG GT+ EV + + VK A+EAG+ ID+A +Y NE+Q+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQV 61
Query: 281 GAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHNPVA 442
G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH PV+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 443 FNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG- 589
PG + FD VD TW+ ME+ K+ GLAKSIG+SNFN ++ IL
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPG 181
Query: 590 -QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVM 685
+ KP QVE + + Q KL+D+CK IV++
Sbjct: 182 LKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLV 214
>AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 144 bits (348), Expect = 3e-34
Identities = 88/213 (41%), Positives = 126/213 (59%), Gaps = 18/213 (8%)
Frame = +2
Query: 101 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 280
+ LNDG+ +P LG GT+ EV + + VK A+EAG+ ID+A +Y NE+Q+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQV 61
Query: 281 GAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHNPVA 442
G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH PV+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 443 FNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG- 589
PG + FD VD TW+ ME+ K+ GLAKSIG+SNFN ++ IL
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPG 181
Query: 590 -QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVM 685
+ KP QVE + + Q KL+D+CK IV++
Sbjct: 182 LKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLV 214
>AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase family
1, member C2 variant protein.
Length = 286
Score = 144 bits (348), Expect = 3e-34
Identities = 88/213 (41%), Positives = 126/213 (59%), Gaps = 18/213 (8%)
Frame = +2
Query: 101 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 280
+ LNDG+ +P LG GT+ EV + + VK A+EAG+ ID+A +Y NE+Q+
Sbjct: 21 VKLNDGHFMPVLGFGTY------APAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQV 74
Query: 281 GAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHNPVA 442
G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH PV+
Sbjct: 75 GLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 134
Query: 443 FNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG- 589
PG + FD VD TW+ ME+ K+ GLAKSIG+SNFN ++ IL
Sbjct: 135 VKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPG 194
Query: 590 -QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVM 685
+ KP QVE + + Q KL+D+CK IV++
Sbjct: 195 LKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLV 227
>AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 144 bits (348), Expect = 3e-34
Identities = 88/213 (41%), Positives = 126/213 (59%), Gaps = 18/213 (8%)
Frame = +2
Query: 101 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 280
+ LNDG+ +P LG GT+ EV + + VK A+EAG+ ID+A +Y NE+Q+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQV 61
Query: 281 GAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHNPVA 442
G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH PV+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 443 FNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG- 589
PG + FD VD TW+ ME+ K+ GLAKSIG+SNFN ++ IL
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPG 181
Query: 590 -QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVM 685
+ KP QVE + + Q KL+D+CK IV++
Sbjct: 182 LKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLV 214
>AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 144 bits (348), Expect = 3e-34
Identities = 88/213 (41%), Positives = 126/213 (59%), Gaps = 18/213 (8%)
Frame = +2
Query: 101 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 280
+ LNDG+ +P LG GT+ EV + + VK A+EAG+ ID+A +Y NE+Q+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQV 61
Query: 281 GAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHNPVA 442
G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH PV+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 443 FNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG- 589
PG + FD VD TW+ ME+ K+ GLAKSIG+SNFN ++ IL
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPG 181
Query: 590 -QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVM 685
+ KP QVE + + Q KL+D+CK IV++
Sbjct: 182 LKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLV 214
>AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding
protein/AKR1C2/3alpha-hydroxysteroid dehydrogenase type
3 protein.
Length = 323
Score = 144 bits (348), Expect = 3e-34
Identities = 88/213 (41%), Positives = 126/213 (59%), Gaps = 18/213 (8%)
Frame = +2
Query: 101 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 280
+ LNDG+ +P LG GT+ EV + + VK A+EAG+ ID+A +Y NE+Q+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQV 61
Query: 281 GAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHNPVA 442
G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH PV+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 443 FNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG- 589
PG + FD VD TW+ ME+ K+ GLAKSIG+SNFN ++ IL
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPG 181
Query: 590 -QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVM 685
+ KP QVE + + Q KL+D+CK IV++
Sbjct: 182 LKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLV 214
>CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 143 bits (347), Expect = 5e-34
Identities = 88/215 (40%), Positives = 130/215 (60%), Gaps = 18/215 (8%)
Frame = +2
Query: 92 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 271
AS++ LN+G +P LGLGT+ + PG + VK A++ GYR ID A +Y NE
Sbjct: 2 ASRLLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNE 52
Query: 272 DQIGAAV----RASGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHN 433
+++G A+ R + RE++FIV+KL +++ +VK +K+L+ L + Y+DLYLIH
Sbjct: 53 NEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHW 112
Query: 434 PVAFNPGFKGFDI----------VDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILE 583
P+ F PG + F + + LDTW MEE + GL K+IGISNFN Q++ IL
Sbjct: 113 PIGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILN 172
Query: 584 NG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVV 682
+ KP+V Q+E + +L Q+KLI YC+ GIVV
Sbjct: 173 KPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVV 207
>J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 143 bits (346), Expect = 6e-34
Identities = 89/215 (41%), Positives = 129/215 (60%), Gaps = 18/215 (8%)
Frame = +2
Query: 92 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 271
AS+I LN+G +P LGLGT+ + PG + VK A++ GYR ID A +Y NE
Sbjct: 2 ASRILLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNE 52
Query: 272 DQIGAAV----RASGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHN 433
+++G A+ R + RE++FIV+KL +++ +VK +K+L+ L + Y+DLYLIH
Sbjct: 53 NEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHW 112
Query: 434 PVAFNPGFKGFDI----------VDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILE 583
P F PG + F + + LDTW MEE + GL K+IGISNFN Q++ IL
Sbjct: 113 PTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILN 172
Query: 584 NG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVV 682
+ KP+V Q+E + +L Q+KLI YC+ GIVV
Sbjct: 173 KPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVV 207
>X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for
aldose reductase (EC 1.1.1.2). ).
Length = 316
Score = 142 bits (344), Expect = 1e-33
Identities = 88/215 (40%), Positives = 129/215 (60%), Gaps = 18/215 (8%)
Frame = +2
Query: 92 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 271
AS++ LN+G +P LGLGT+ + PG + VK A++ GYR ID A +Y NE
Sbjct: 2 ASRLLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNE 52
Query: 272 DQIGAAV----RASGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHN 433
+++G A+ R + RE++FIV+KL +++ +VK +K+L+ L + Y+DLYLIH
Sbjct: 53 NEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHW 112
Query: 434 PVAFNPGFKGFDI----------VDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILE 583
P F PG + F + + LDTW MEE + GL K+IGISNFN Q++ IL
Sbjct: 113 PTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILN 172
Query: 584 NG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVV 682
+ KP+V Q+E + +L Q+KLI YC+ GIVV
Sbjct: 173 KPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVV 207
>M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 142 bits (344), Expect = 1e-33
Identities = 88/215 (40%), Positives = 129/215 (60%), Gaps = 18/215 (8%)
Frame = +2
Query: 92 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 271
AS++ LN+G +P LGLGT+ + PG + VK A++ GYR ID A +Y NE
Sbjct: 2 ASRLLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNE 52
Query: 272 DQIGAAV----RASGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHN 433
+++G A+ R + RE++FIV+KL +++ +VK +K+L+ L + Y+DLYLIH
Sbjct: 53 NEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHW 112
Query: 434 PVAFNPGFKGFDI----------VDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILE 583
P F PG + F + + LDTW MEE + GL K+IGISNFN Q++ IL
Sbjct: 113 PTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILN 172
Query: 584 NG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVV 682
+ KP+V Q+E + +L Q+KLI YC+ GIVV
Sbjct: 173 KPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVV 207
>M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose
reductase mRNA, complete cds. ).
Length = 316
Score = 142 bits (344), Expect = 1e-33
Identities = 88/215 (40%), Positives = 129/215 (60%), Gaps = 18/215 (8%)
Frame = +2
Query: 92 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 271
AS++ LN+G +P LGLGT+ + PG + VK A++ GYR ID A +Y NE
Sbjct: 2 ASRLLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNE 52
Query: 272 DQIGAAV----RASGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHN 433
+++G A+ R + RE++FIV+KL +++ +VK +K+L+ L + Y+DLYLIH
Sbjct: 53 NEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHW 112
Query: 434 PVAFNPGFKGFDI----------VDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILE 583
P F PG + F + + LDTW MEE + GL K+IGISNFN Q++ IL
Sbjct: 113 PTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILN 172
Query: 584 NG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVV 682
+ KP+V Q+E + +L Q+KLI YC+ GIVV
Sbjct: 173 KPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVV 207
>J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 142 bits (344), Expect = 1e-33
Identities = 88/215 (40%), Positives = 129/215 (60%), Gaps = 18/215 (8%)
Frame = +2
Query: 92 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 271
AS++ LN+G +P LGLGT+ + PG + VK A++ GYR ID A +Y NE
Sbjct: 2 ASRLLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNE 52
Query: 272 DQIGAAV----RASGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHN 433
+++G A+ R + RE++FIV+KL +++ +VK +K+L+ L + Y+DLYLIH
Sbjct: 53 NEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHW 112
Query: 434 PVAFNPGFKGFDI----------VDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILE 583
P F PG + F + + LDTW MEE + GL K+IGISNFN Q++ IL
Sbjct: 113 PTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILN 172
Query: 584 NG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVV 682
+ KP+V Q+E + +L Q+KLI YC+ GIVV
Sbjct: 173 KPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVV 207
>J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 142 bits (344), Expect = 1e-33
Identities = 88/215 (40%), Positives = 129/215 (60%), Gaps = 18/215 (8%)
Frame = +2
Query: 92 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 271
AS++ LN+G +P LGLGT+ + PG + VK A++ GYR ID A +Y NE
Sbjct: 2 ASRLLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNE 52
Query: 272 DQIGAAV----RASGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHN 433
+++G A+ R + RE++FIV+KL +++ +VK +K+L+ L + Y+DLYLIH
Sbjct: 53 NEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHW 112
Query: 434 PVAFNPGFKGFDI----------VDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILE 583
P F PG + F + + LDTW MEE + GL K+IGISNFN Q++ IL
Sbjct: 113 PTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILN 172
Query: 584 NG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVV 682
+ KP+V Q+E + +L Q+KLI YC+ GIVV
Sbjct: 173 KPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVV 207
>CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 142 bits (344), Expect = 1e-33
Identities = 88/215 (40%), Positives = 129/215 (60%), Gaps = 18/215 (8%)
Frame = +2
Query: 92 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 271
AS++ LN+G +P LGLGT+ + PG + VK A++ GYR ID A +Y NE
Sbjct: 2 ASRLLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNE 52
Query: 272 DQIGAAV----RASGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHN 433
+++G A+ R + RE++FIV+KL +++ +VK +K+L+ L + Y+DLYLIH
Sbjct: 53 NEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHW 112
Query: 434 PVAFNPGFKGFDI----------VDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILE 583
P F PG + F + + LDTW MEE + GL K+IGISNFN Q++ IL
Sbjct: 113 PTGFRPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILS 172
Query: 584 NG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVV 682
+ KP+V Q+E + +L Q+KLI YC+ GIVV
Sbjct: 173 KPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVV 207
>BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 142 bits (344), Expect = 1e-33
Identities = 88/215 (40%), Positives = 129/215 (60%), Gaps = 18/215 (8%)
Frame = +2
Query: 92 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 271
AS++ LN+G +P LGLGT+ + PG + VK A++ GYR ID A +Y NE
Sbjct: 2 ASRLLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNE 52
Query: 272 DQIGAAV----RASGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHN 433
+++G A+ R + RE++FIV+KL +++ +VK +K+L+ L + Y+DLYLIH
Sbjct: 53 NEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHW 112
Query: 434 PVAFNPGFKGFDI----------VDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILE 583
P F PG + F + + LDTW MEE + GL K+IGISNFN Q++ IL
Sbjct: 113 PTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILN 172
Query: 584 NG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVV 682
+ KP+V Q+E + +L Q+KLI YC+ GIVV
Sbjct: 173 KPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVV 207
>BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 142 bits (344), Expect = 1e-33
Identities = 88/215 (40%), Positives = 129/215 (60%), Gaps = 18/215 (8%)
Frame = +2
Query: 92 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 271
AS++ LN+G +P LGLGT+ + PG + VK A++ GYR ID A +Y NE
Sbjct: 2 ASRLLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNE 52
Query: 272 DQIGAAV----RASGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHN 433
+++G A+ R + RE++FIV+KL +++ +VK +K+L+ L + Y+DLYLIH
Sbjct: 53 NEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHW 112
Query: 434 PVAFNPGFKGFDI----------VDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILE 583
P F PG + F + + LDTW MEE + GL K+IGISNFN Q++ IL
Sbjct: 113 PTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILN 172
Query: 584 NG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVV 682
+ KP+V Q+E + +L Q+KLI YC+ GIVV
Sbjct: 173 KPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVV 207
>BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 142 bits (344), Expect = 1e-33
Identities = 88/215 (40%), Positives = 129/215 (60%), Gaps = 18/215 (8%)
Frame = +2
Query: 92 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 271
AS++ LN+G +P LGLGT+ + PG + VK A++ GYR ID A +Y NE
Sbjct: 2 ASRLLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNE 52
Query: 272 DQIGAAV----RASGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHN 433
+++G A+ R + RE++FIV+KL +++ +VK +K+L+ L + Y+DLYLIH
Sbjct: 53 NEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHW 112
Query: 434 PVAFNPGFKGFDI----------VDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILE 583
P F PG + F + + LDTW MEE + GL K+IGISNFN Q++ IL
Sbjct: 113 PTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILN 172
Query: 584 NG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVV 682
+ KP+V Q+E + +L Q+KLI YC+ GIVV
Sbjct: 173 KPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVV 207
>AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen
HD-CL-07 protein.
Length = 316
Score = 142 bits (344), Expect = 1e-33
Identities = 88/215 (40%), Positives = 129/215 (60%), Gaps = 18/215 (8%)
Frame = +2
Query: 92 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 271
AS++ LN+G +P LGLGT+ + PG + VK A++ GYR ID A +Y NE
Sbjct: 2 ASRLLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNE 52
Query: 272 DQIGAAV----RASGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHN 433
+++G A+ R + RE++FIV+KL +++ +VK +K+L+ L + Y+DLYLIH
Sbjct: 53 NEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHW 112
Query: 434 PVAFNPGFKGFDI----------VDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILE 583
P F PG + F + + LDTW MEE + GL K+IGISNFN Q++ IL
Sbjct: 113 PTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILN 172
Query: 584 NG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVV 682
+ KP+V Q+E + +L Q+KLI YC+ GIVV
Sbjct: 173 KPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVV 207
>AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 142 bits (344), Expect = 1e-33
Identities = 88/215 (40%), Positives = 129/215 (60%), Gaps = 18/215 (8%)
Frame = +2
Query: 92 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 271
AS++ LN+G +P LGLGT+ + PG + VK A++ GYR ID A +Y NE
Sbjct: 2 ASRLLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNE 52
Query: 272 DQIGAAV----RASGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHN 433
+++G A+ R + RE++FIV+KL +++ +VK +K+L+ L + Y+DLYLIH
Sbjct: 53 NEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHW 112
Query: 434 PVAFNPGFKGFDI----------VDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILE 583
P F PG + F + + LDTW MEE + GL K+IGISNFN Q++ IL
Sbjct: 113 PTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILN 172
Query: 584 NG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVV 682
+ KP+V Q+E + +L Q+KLI YC+ GIVV
Sbjct: 173 KPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVV 207
>J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein.
Length = 325
Score = 140 bits (340), Expect = 3e-33
Identities = 83/214 (38%), Positives = 123/214 (57%), Gaps = 17/214 (7%)
Frame = +2
Query: 92 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 271
AS + L+ G +P +GLGT+ + +PG + VK+AL GYR ID AA+Y NE
Sbjct: 3 ASCVLLHTGQKMPLIGLGTW---------KSEPGQVKAAVKYALSVGYRHIDCAAIYGNE 53
Query: 272 DQIGAAVR-----ASGIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIH 430
+IG A++ +PRE++F+ +KL + DV L K+LA L + Y+DLYL+H
Sbjct: 54 PEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMH 113
Query: 431 NPVAFNPGFKGF----------DIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL 580
P AF G F D Y +TWK +E GL +++G+SNFN+ QID IL
Sbjct: 114 WPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDIL 173
Query: 581 ENGQIKPSVLQVEVNLHLGQDKLIDYCKRNGIVV 682
++P+VLQVE + +L Q++LI +C+ G+ V
Sbjct: 174 SVASVRPAVLQVECHPYLAQNELIAHCQARGLEV 207
>CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein.
Length = 325
Score = 140 bits (340), Expect = 3e-33
Identities = 83/214 (38%), Positives = 123/214 (57%), Gaps = 17/214 (7%)
Frame = +2
Query: 92 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 271
AS + L+ G +P +GLGT+ + +PG + VK+AL GYR ID AA+Y NE
Sbjct: 3 ASCVLLHTGQKMPLIGLGTW---------KSEPGQVKAAVKYALSVGYRHIDCAAIYGNE 53
Query: 272 DQIGAAVR-----ASGIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIH 430
+IG A++ +PRE++F+ +KL + DV L K+LA L + Y+DLYL+H
Sbjct: 54 PEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMH 113
Query: 431 NPVAFNPGFKGF----------DIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL 580
P AF G F D Y +TWK +E GL +++G+SNFN+ QID IL
Sbjct: 114 WPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDIL 173
Query: 581 ENGQIKPSVLQVEVNLHLGQDKLIDYCKRNGIVV 682
++P+VLQVE + +L Q++LI +C+ G+ V
Sbjct: 174 SVASVRPAVLQVECHPYLAQNELIAHCQARGLEV 207
>BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 140 bits (340), Expect = 3e-33
Identities = 83/214 (38%), Positives = 123/214 (57%), Gaps = 17/214 (7%)
Frame = +2
Query: 92 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 271
AS + L+ G +P +GLGT+ + +PG + VK+AL GYR ID AA+Y NE
Sbjct: 3 ASCVLLHTGQKMPLIGLGTW---------KSEPGQVKAAVKYALSVGYRHIDCAAIYGNE 53
Query: 272 DQIGAAVR-----ASGIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIH 430
+IG A++ +PRE++F+ +KL + DV L K+LA L + Y+DLYL+H
Sbjct: 54 PEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMH 113
Query: 431 NPVAFNPGFKGF----------DIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL 580
P AF G F D Y +TWK +E GL +++G+SNFN+ QID IL
Sbjct: 114 WPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDIL 173
Query: 581 ENGQIKPSVLQVEVNLHLGQDKLIDYCKRNGIVV 682
++P+VLQVE + +L Q++LI +C+ G+ V
Sbjct: 174 SVASVRPAVLQVECHPYLAQNELIAHCQARGLEV 207
>BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 140 bits (340), Expect = 3e-33
Identities = 83/214 (38%), Positives = 123/214 (57%), Gaps = 17/214 (7%)
Frame = +2
Query: 92 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 271
AS + L+ G +P +GLGT+ + +PG + VK+AL GYR ID AA+Y NE
Sbjct: 3 ASCVLLHTGQKMPLIGLGTW---------KSEPGQVKAAVKYALSVGYRHIDCAAIYGNE 53
Query: 272 DQIGAAVR-----ASGIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIH 430
+IG A++ +PRE++F+ +KL + DV L K+LA L + Y+DLYL+H
Sbjct: 54 PEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMH 113
Query: 431 NPVAFNPGFKGF----------DIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL 580
P AF G F D Y +TWK +E GL +++G+SNFN+ QID IL
Sbjct: 114 WPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDIL 173
Query: 581 ENGQIKPSVLQVEVNLHLGQDKLIDYCKRNGIVV 682
++P+VLQVE + +L Q++LI +C+ G+ V
Sbjct: 174 SVASVRPAVLQVECHPYLAQNELIAHCQARGLEV 207
>BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 140 bits (340), Expect = 3e-33
Identities = 83/214 (38%), Positives = 123/214 (57%), Gaps = 17/214 (7%)
Frame = +2
Query: 92 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 271
AS + L+ G +P +GLGT+ + +PG + VK+AL GYR ID AA+Y NE
Sbjct: 3 ASCVLLHTGQKMPLIGLGTW---------KSEPGQVKAAVKYALSVGYRHIDCAAIYGNE 53
Query: 272 DQIGAAVR-----ASGIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIH 430
+IG A++ +PRE++F+ +KL + DV L K+LA L + Y+DLYL+H
Sbjct: 54 PEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMH 113
Query: 431 NPVAFNPGFKGF----------DIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL 580
P AF G F D Y +TWK +E GL +++G+SNFN+ QID IL
Sbjct: 114 WPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDIL 173
Query: 581 ENGQIKPSVLQVEVNLHLGQDKLIDYCKRNGIVV 682
++P+VLQVE + +L Q++LI +C+ G+ V
Sbjct: 174 SVASVRPAVLQVECHPYLAQNELIAHCQARGLEV 207
>AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydetase, 1 protein.
Length = 325
Score = 140 bits (340), Expect = 3e-33
Identities = 83/214 (38%), Positives = 123/214 (57%), Gaps = 17/214 (7%)
Frame = +2
Query: 92 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 271
AS + L+ G +P +GLGT+ + +PG + VK+AL GYR ID AA+Y NE
Sbjct: 3 ASCVLLHTGQKMPLIGLGTW---------KSEPGQVKAAVKYALSVGYRHIDCAAIYGNE 53
Query: 272 DQIGAAVR-----ASGIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIH 430
+IG A++ +PRE++F+ +KL + DV L K+LA L + Y+DLYL+H
Sbjct: 54 PEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMH 113
Query: 431 NPVAFNPGFKGF----------DIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL 580
P AF G F D Y +TWK +E GL +++G+SNFN+ QID IL
Sbjct: 114 WPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDIL 173
Query: 581 ENGQIKPSVLQVEVNLHLGQDKLIDYCKRNGIVV 682
++P+VLQVE + +L Q++LI +C+ G+ V
Sbjct: 174 SVASVRPAVLQVECHPYLAQNELIAHCQARGLEV 207
>AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 140 bits (340), Expect = 3e-33
Identities = 83/214 (38%), Positives = 123/214 (57%), Gaps = 17/214 (7%)
Frame = +2
Query: 92 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 271
AS + L+ G +P +GLGT+ + +PG + VK+AL GYR ID AA+Y NE
Sbjct: 3 ASCVLLHTGQKMPLIGLGTW---------KSEPGQVKAAVKYALSVGYRHIDCAAIYGNE 53
Query: 272 DQIGAAVR-----ASGIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIH 430
+IG A++ +PRE++F+ +KL + DV L K+LA L + Y+DLYL+H
Sbjct: 54 PEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMH 113
Query: 431 NPVAFNPGFKGF----------DIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL 580
P AF G F D Y +TWK +E GL +++G+SNFN+ QID IL
Sbjct: 114 WPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDIL 173
Query: 581 ENGQIKPSVLQVEVNLHLGQDKLIDYCKRNGIVV 682
++P+VLQVE + +L Q++LI +C+ G+ V
Sbjct: 174 SVASVRPAVLQVECHPYLAQNELIAHCQARGLEV 207
>AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 140 bits (340), Expect = 3e-33
Identities = 83/214 (38%), Positives = 123/214 (57%), Gaps = 17/214 (7%)
Frame = +2
Query: 92 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 271
AS + L+ G +P +GLGT+ + +PG + VK+AL GYR ID AA+Y NE
Sbjct: 3 ASCVLLHTGQKMPLIGLGTW---------KSEPGQVKAAVKYALSVGYRHIDCAAIYGNE 53
Query: 272 DQIGAAVR-----ASGIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIH 430
+IG A++ +PRE++F+ +KL + DV L K+LA L + Y+DLYL+H
Sbjct: 54 PEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMH 113
Query: 431 NPVAFNPGFKGF----------DIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL 580
P AF G F D Y +TWK +E GL +++G+SNFN+ QID IL
Sbjct: 114 WPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDIL 173
Query: 581 ENGQIKPSVLQVEVNLHLGQDKLIDYCKRNGIVV 682
++P+VLQVE + +L Q++LI +C+ G+ V
Sbjct: 174 SVASVRPAVLQVECHPYLAQNELIAHCQARGLEV 207
>AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase family
1, member B1 variant protein.
Length = 260
Score = 139 bits (336), Expect = 1e-32
Identities = 86/213 (40%), Positives = 127/213 (59%), Gaps = 18/213 (8%)
Frame = +2
Query: 98 KISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQ 277
++ LN+G +P LGLGT+ + PG + VK A++ GYR ID A +Y NE++
Sbjct: 1 RLLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENE 51
Query: 278 IGAAV----RASGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHNPV 439
+G A+ R + RE++FIV+KL +++ +VK +K+L+ L + Y+DLYLIH P
Sbjct: 52 VGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPT 111
Query: 440 AFNPGFKGFDI----------VDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG 589
F PG + F + + LDTW MEE + GL K+IGISNFN Q++ IL
Sbjct: 112 GFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKP 171
Query: 590 --QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVV 682
+ KP+V Q+E + +L Q+KLI YC+ GIVV
Sbjct: 172 GLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVV 204
>D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase
isoform DD1 protein.
Length = 306
Score = 138 bits (333), Expect = 2e-32
Identities = 83/196 (42%), Positives = 117/196 (59%), Gaps = 18/196 (9%)
Frame = +2
Query: 152 LGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGAAVRAS----GIPRED 319
LGF EV + + K A+EAG+R ID+A LY NE+Q+G A+R+ + RED
Sbjct: 2 LGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKRED 61
Query: 320 IFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHNPVAFNPGFKG---------- 463
IF +KL ++ R ++V+ LE+SL L + YVDLYLIH PV+ PG +
Sbjct: 62 IFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKIL 121
Query: 464 FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLG 637
FD VD TW+ +E+ K+ GLAKSIG+SNFN Q++ IL + KP QVE + +
Sbjct: 122 FDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFN 181
Query: 638 QDKLIDYCKRNGIVVM 685
Q KL+D+CK IV++
Sbjct: 182 QRKLLDFCKSKDIVLV 197
>BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 136 bits (330), Expect = 5e-32
Identities = 87/215 (40%), Positives = 128/215 (59%), Gaps = 18/215 (8%)
Frame = +2
Query: 92 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 271
AS++ LN+G +P LGLGT+ + PG + VK A++ GYR ID A +Y NE
Sbjct: 2 ASRLLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNE 52
Query: 272 DQIGAAV----RASGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHN 433
+++G A+ R + RE++FIV+KL +++ +VK +K+L+ L + Y+DLYLIH
Sbjct: 53 NEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHW 112
Query: 434 PVAFNPGFKGFDI----------VDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILE 583
P F PG + F + + LDT MEE + GL K+IGISNFN Q++ IL
Sbjct: 113 PTGFKPGKEFFPLDESGNVVPSDTNILDTRAAMEELVDEGLVKAIGISNFNHLQVEMILN 172
Query: 584 NG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVV 682
+ KP+V Q+E + +L Q+KLI YC+ GIVV
Sbjct: 173 KPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVV 207
>M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordecone
reductase mRNA, complete cds. ).
Length = 308
Score = 135 bits (327), Expect = 1e-31
Identities = 83/196 (42%), Positives = 112/196 (57%), Gaps = 18/196 (9%)
Frame = +2
Query: 152 LGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGAAVRAS----GIPRED 319
LGF EV + + K A+EAG+R ID+A LY NE+Q+G A+R+ + RED
Sbjct: 4 LGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGSVKRED 63
Query: 320 IFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVAFNPGFKG---------- 463
IF +KL + V LE SL +L + YVDLYL+H P+A PG
Sbjct: 64 IFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETPLPKDENGKVI 123
Query: 464 FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLG 637
FD VD TW+ ME+ K+ GLAKSIG+SNFN Q++ IL + KP QVE + +L
Sbjct: 124 FDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLN 183
Query: 638 QDKLIDYCKRNGIVVM 685
Q KL+D+CK IV++
Sbjct: 184 QSKLLDFCKSKDIVLV 199
>Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5
beta-reductase protein.
Length = 326
Score = 126 bits (303), Expect = 1e-28
Identities = 84/213 (39%), Positives = 121/213 (56%), Gaps = 18/213 (8%)
Frame = +2
Query: 98 KISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQ 277
+I L+DGNSIP +GLGT+ K G VK A++ GYR ID A +Y NE +
Sbjct: 9 RIPLSDGNSIPIIGLGTY-----SEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHE 63
Query: 278 IGAAVR---ASG-IPREDIFIVTKLPMDNQ-RDVVK-QLEKSLARLNMSYVDLYLIHNPV 439
+G A+R A G + REDIF KL N ++V+ LE++L L + YVDLY+I P+
Sbjct: 64 VGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPM 123
Query: 440 AFNPGFK-------G---FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG 589
AF PG + G + + TW+ ME K+ GL KS+G+SNFN Q++ IL
Sbjct: 124 AFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKP 183
Query: 590 QI--KPSVLQVEVNLHLGQDKLIDYCKRNGIVV 682
+ KP QVE + + Q KL+ +C+++ IV+
Sbjct: 184 GLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVI 216
>BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 126 bits (303), Expect = 1e-28
Identities = 84/213 (39%), Positives = 121/213 (56%), Gaps = 18/213 (8%)
Frame = +2
Query: 98 KISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQ 277
+I L+DGNSIP +GLGT+ K G VK A++ GYR ID A +Y NE +
Sbjct: 9 RIPLSDGNSIPIIGLGTY-----SEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHE 63
Query: 278 IGAAVR---ASG-IPREDIFIVTKLPMDNQ-RDVVK-QLEKSLARLNMSYVDLYLIHNPV 439
+G A+R A G + REDIF KL N ++V+ LE++L L + YVDLY+I P+
Sbjct: 64 VGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPM 123
Query: 440 AFNPGFK-------G---FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG 589
AF PG + G + + TW+ ME K+ GL KS+G+SNFN Q++ IL
Sbjct: 124 AFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKP 183
Query: 590 QI--KPSVLQVEVNLHLGQDKLIDYCKRNGIVV 682
+ KP QVE + + Q KL+ +C+++ IV+
Sbjct: 184 GLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVI 216
>BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 126 bits (303), Expect = 1e-28
Identities = 84/213 (39%), Positives = 121/213 (56%), Gaps = 18/213 (8%)
Frame = +2
Query: 98 KISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQ 277
+I L+DGNSIP +GLGT+ K G VK A++ GYR ID A +Y NE +
Sbjct: 9 RIPLSDGNSIPIIGLGTY-----SEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHE 63
Query: 278 IGAAVR---ASG-IPREDIFIVTKLPMDNQ-RDVVK-QLEKSLARLNMSYVDLYLIHNPV 439
+G A+R A G + REDIF KL N ++V+ LE++L L + YVDLY+I P+
Sbjct: 64 VGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPM 123
Query: 440 AFNPGFK-------G---FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG 589
AF PG + G + + TW+ ME K+ GL KS+G+SNFN Q++ IL
Sbjct: 124 AFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKP 183
Query: 590 QI--KPSVLQVEVNLHLGQDKLIDYCKRNGIVV 682
+ KP QVE + + Q KL+ +C+++ IV+
Sbjct: 184 GLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVI 216
>AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductase
protein.
Length = 326
Score = 126 bits (303), Expect = 1e-28
Identities = 84/213 (39%), Positives = 121/213 (56%), Gaps = 18/213 (8%)
Frame = +2
Query: 98 KISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQ 277
+I L+DGNSIP +GLGT+ K G VK A++ GYR ID A +Y NE +
Sbjct: 9 RIPLSDGNSIPIIGLGTY-----SEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHE 63
Query: 278 IGAAVR---ASG-IPREDIFIVTKLPMDNQ-RDVVK-QLEKSLARLNMSYVDLYLIHNPV 439
+G A+R A G + REDIF KL N ++V+ LE++L L + YVDLY+I P+
Sbjct: 64 VGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPM 123
Query: 440 AFNPGFK-------G---FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG 589
AF PG + G + + TW+ ME K+ GL KS+G+SNFN Q++ IL
Sbjct: 124 AFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKP 183
Query: 590 QI--KPSVLQVEVNLHLGQDKLIDYCKRNGIVV 682
+ KP QVE + + Q KL+ +C+++ IV+
Sbjct: 184 GLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVI 216
>U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like
peptide protein.
Length = 316
Score = 122 bits (293), Expect = 2e-27
Identities = 82/215 (38%), Positives = 121/215 (56%), Gaps = 18/215 (8%)
Frame = +2
Query: 92 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 271
A+ + L+ +P +GLGT+ + G ++ VK A++AGYR ID A +Y NE
Sbjct: 2 ATFVELSTKAKMPIVGLGTW---------KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNE 52
Query: 272 DQIGAAVRAS----GIPREDIFIVTKL-PMDNQRDVV-KQLEKSLARLNMSYVDLYLIHN 433
++G A++ + RED+FIV+KL P +R +V K EK+L L +SY+D+YLIH
Sbjct: 53 HEVGEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHW 112
Query: 434 PVAFNPGFKGFDIVD----------YLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILE 583
P F G F D +LD W+ MEE + GL K++G+SNF+ QI+++L
Sbjct: 113 PQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLN 172
Query: 584 NG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVV 682
+ KP QVE + +L Q+KLI YC GI V
Sbjct: 173 KPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITV 207
>CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein.
Length = 316
Score = 122 bits (293), Expect = 2e-27
Identities = 82/215 (38%), Positives = 121/215 (56%), Gaps = 18/215 (8%)
Frame = +2
Query: 92 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 271
A+ + L+ +P +GLGT+ + G ++ VK A++AGYR ID A +Y NE
Sbjct: 2 ATFVELSTKAKMPIVGLGTW---------KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNE 52
Query: 272 DQIGAAVRAS----GIPREDIFIVTKL-PMDNQRDVV-KQLEKSLARLNMSYVDLYLIHN 433
++G A++ + RED+FIV+KL P +R +V K EK+L L +SY+D+YLIH
Sbjct: 53 HEVGEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHW 112
Query: 434 PVAFNPGFKGFDIVD----------YLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILE 583
P F G F D +LD W+ MEE + GL K++G+SNF+ QI+++L
Sbjct: 113 PQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLN 172
Query: 584 NG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVV 682
+ KP QVE + +L Q+KLI YC GI V
Sbjct: 173 KPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITV 207
>BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 122 bits (293), Expect = 2e-27
Identities = 82/215 (38%), Positives = 121/215 (56%), Gaps = 18/215 (8%)
Frame = +2
Query: 92 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 271
A+ + L+ +P +GLGT+ + G ++ VK A++AGYR ID A +Y NE
Sbjct: 2 ATFVELSTKAKMPIVGLGTW---------KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNE 52
Query: 272 DQIGAAVRAS----GIPREDIFIVTKL-PMDNQRDVV-KQLEKSLARLNMSYVDLYLIHN 433
++G A++ + RED+FIV+KL P +R +V K EK+L L +SY+D+YLIH
Sbjct: 53 HEVGEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHW 112
Query: 434 PVAFNPGFKGFDIVD----------YLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILE 583
P F G F D +LD W+ MEE + GL K++G+SNF+ QI+++L
Sbjct: 113 PQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLN 172
Query: 584 NG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVV 682
+ KP QVE + +L Q+KLI YC GI V
Sbjct: 173 KPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITV 207
>BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 122 bits (293), Expect = 2e-27
Identities = 82/215 (38%), Positives = 121/215 (56%), Gaps = 18/215 (8%)
Frame = +2
Query: 92 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 271
A+ + L+ +P +GLGT+ + G ++ VK A++AGYR ID A +Y NE
Sbjct: 2 ATFVELSTKAKMPIVGLGTW---------KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNE 52
Query: 272 DQIGAAVRAS----GIPREDIFIVTKL-PMDNQRDVV-KQLEKSLARLNMSYVDLYLIHN 433
++G A++ + RED+FIV+KL P +R +V K EK+L L +SY+D+YLIH
Sbjct: 53 HEVGEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHW 112
Query: 434 PVAFNPGFKGFDIVD----------YLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILE 583
P F G F D +LD W+ MEE + GL K++G+SNF+ QI+++L
Sbjct: 113 PQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLN 172
Query: 584 NG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVV 682
+ KP QVE + +L Q+KLI YC GI V
Sbjct: 173 KPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITV 207
>AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase
protein.
Length = 316
Score = 122 bits (293), Expect = 2e-27
Identities = 82/215 (38%), Positives = 121/215 (56%), Gaps = 18/215 (8%)
Frame = +2
Query: 92 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 271
A+ + L+ +P +GLGT+ + G ++ VK A++AGYR ID A +Y NE
Sbjct: 2 ATFVELSTKAKMPIVGLGTW---------KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNE 52
Query: 272 DQIGAAVRAS----GIPREDIFIVTKL-PMDNQRDVV-KQLEKSLARLNMSYVDLYLIHN 433
++G A++ + RED+FIV+KL P +R +V K EK+L L +SY+D+YLIH
Sbjct: 53 HEVGEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHW 112
Query: 434 PVAFNPGFKGFDIVD----------YLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILE 583
P F G F D +LD W+ MEE + GL K++G+SNF+ QI+++L
Sbjct: 113 PQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLN 172
Query: 584 NG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVV 682
+ KP QVE + +L Q+KLI YC GI V
Sbjct: 173 KPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITV 207
>AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase
protein.
Length = 316
Score = 117 bits (282), Expect = 3e-26
Identities = 80/215 (37%), Positives = 119/215 (55%), Gaps = 18/215 (8%)
Frame = +2
Query: 92 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 271
A+ + L+ +P +GLGT+ + G ++ VK A++AGYR ID A +Y NE
Sbjct: 2 ATFVELSTKAKMPIVGLGTW---------KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNE 52
Query: 272 DQIGAAVRAS----GIPREDIFIVTKL-PMDNQRDVV-KQLEKSLARLNMSYVDLYLIHN 433
++G A++ + RED+FI +KL P +R +V K EK+L +SY+D+YLIH
Sbjct: 53 HEVGEAIQEKIQEKAVKREDLFIASKLWPTFFERPLVRKAFEKTLKDPKLSYLDVYLIHW 112
Query: 434 PVAFNPGFKGFDIVD----------YLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILE 583
P F G F D +LD W+ MEE + GL K++G+SNF+ QI+++L
Sbjct: 113 PQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLN 172
Query: 584 NG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVV 682
+ KP QVE + +L Q+KLI YC GI V
Sbjct: 173 KPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITV 207
>AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase
loopADR protein.
Length = 320
Score = 72.1 bits (169), Expect(2) = 6e-25
Identities = 45/115 (39%), Positives = 66/115 (57%), Gaps = 6/115 (5%)
Frame = +2
Query: 125 IPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGAAVRA-- 298
IPA+GL ++ + PG + VK A++AGYR D A Y NE ++GA +R
Sbjct: 4 IPAVGLSSW---------KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKI 54
Query: 299 --SGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHNPVAFNP 451
+ RED+FI TKL +++ +V+ KSL L ++Y+DLYLIH P+ F P
Sbjct: 55 KEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKP 109
Score = 62.1 bits (144), Expect(2) = 6e-25
Identities = 29/71 (40%), Positives = 44/71 (61%), Gaps = 2/71 (2%)
Frame = +2
Query: 476 DYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLGQDKL 649
D+LDTW+ ME+ GL K+IG+SNFN Q++R+L + KP Q+E + +L Q L
Sbjct: 147 DFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYLTQKNL 206
Query: 650 IDYCKRNGIVV 682
I +C+ + V
Sbjct: 207 ISFCQSRDVSV 217
>BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein.
Length = 307
Score = 72.1 bits (169), Expect(2) = 6e-25
Identities = 45/115 (39%), Positives = 66/115 (57%), Gaps = 6/115 (5%)
Frame = +2
Query: 125 IPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGAAVRA-- 298
IPA+GL ++ + PG + VK A++AGYR D A Y NE ++GA +R
Sbjct: 4 IPAVGLSSW---------KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKI 54
Query: 299 --SGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHNPVAFNP 451
+ RED+FI TKL +++ +V+ KSL L ++Y+DLYLIH P+ F P
Sbjct: 55 KEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKP 109
Score = 62.1 bits (144), Expect(2) = 6e-25
Identities = 29/71 (40%), Positives = 44/71 (61%), Gaps = 2/71 (2%)
Frame = +2
Query: 476 DYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLGQDKL 649
D+LDTW+ ME+ GL K+IG+SNFN Q++R+L + KP Q+E + +L Q L
Sbjct: 147 DFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYLTQKNL 206
Query: 650 IDYCKRNGIVV 682
I +C+ + V
Sbjct: 207 ISFCQSRDVSV 217
>AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase
related protein 4 protein.
Length = 307
Score = 72.1 bits (169), Expect(2) = 6e-25
Identities = 45/115 (39%), Positives = 66/115 (57%), Gaps = 6/115 (5%)
Frame = +2
Query: 125 IPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGAAVRA-- 298
IPA+GL ++ + PG + VK A++AGYR D A Y NE ++GA +R
Sbjct: 4 IPAVGLSSW---------KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKI 54
Query: 299 --SGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHNPVAFNP 451
+ RED+FI TKL +++ +V+ KSL L ++Y+DLYLIH P+ F P
Sbjct: 55 KEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKP 109
Score = 62.1 bits (144), Expect(2) = 6e-25
Identities = 29/71 (40%), Positives = 44/71 (61%), Gaps = 2/71 (2%)
Frame = +2
Query: 476 DYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLGQDKL 649
D+LDTW+ ME+ GL K+IG+SNFN Q++R+L + KP Q+E + +L Q L
Sbjct: 147 DFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYLTQKNL 206
Query: 650 IDYCKRNGIVV 682
I +C+ + V
Sbjct: 207 ISFCQSRDVSV 217
>AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 247
Score = 105 bits (253), Expect = 1e-22
Identities = 64/155 (41%), Positives = 93/155 (60%), Gaps = 18/155 (11%)
Frame = +2
Query: 275 QIGAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHNP 436
++G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH P
Sbjct: 26 EVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFP 85
Query: 437 VAFNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILEN 586
V+ PG + FD VD TW+ +E+ K+ GLAKSIG+SNFN Q++ IL
Sbjct: 86 VSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNK 145
Query: 587 G--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVM 685
+ KP QVE + + Q KL+D+CK IV++
Sbjct: 146 PGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLV 180
>AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase
related protein 2 protein.
Length = 263
Score = 72.1 bits (169), Expect(2) = 2e-21
Identities = 45/115 (39%), Positives = 66/115 (57%), Gaps = 6/115 (5%)
Frame = +2
Query: 125 IPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGAAVRA-- 298
IPA+GL ++ + PG + VK A++AGYR D A Y NE ++GA +R
Sbjct: 4 IPAVGLSSW---------KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKI 54
Query: 299 --SGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHNPVAFNP 451
+ RED+FI TKL +++ +V+ KSL L ++Y+DLYLIH P+ F P
Sbjct: 55 KEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKP 109
Score = 50.4 bits (115), Expect(2) = 2e-21
Identities = 22/61 (36%), Positives = 38/61 (62%), Gaps = 2/61 (3%)
Frame = +2
Query: 476 DYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLGQDKL 649
D+LDTW+ ME+ GL K+IG+SNFN Q++R+L + KP Q+ + + ++ +
Sbjct: 147 DFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQILIRFQIQRNVI 206
Query: 650 I 652
+
Sbjct: 207 V 207
>AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase
related protein 1 protein.
Length = 250
Score = 72.1 bits (169), Expect(2) = 2e-21
Identities = 45/115 (39%), Positives = 66/115 (57%), Gaps = 6/115 (5%)
Frame = +2
Query: 125 IPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGAAVRA-- 298
IPA+GL ++ + PG + VK A++AGYR D A Y NE ++GA +R
Sbjct: 4 IPAVGLSSW---------KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKI 54
Query: 299 --SGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHNPVAFNP 451
+ RED+FI TKL +++ +V+ KSL L ++Y+DLYLIH P+ F P
Sbjct: 55 KEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKP 109
Score = 50.4 bits (115), Expect(2) = 2e-21
Identities = 22/61 (36%), Positives = 38/61 (62%), Gaps = 2/61 (3%)
Frame = +2
Query: 476 DYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLGQDKL 649
D+LDTW+ ME+ GL K+IG+SNFN Q++R+L + KP Q+ + + ++ +
Sbjct: 147 DFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQILIRFQIQRNVI 206
Query: 650 I 652
+
Sbjct: 207 V 207
>AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydela) protein.
Length = 147
Score = 88.2 bits (209), Expect = 2e-17
Identities = 58/154 (37%), Positives = 84/154 (54%), Gaps = 17/154 (11%)
Frame = +2
Query: 92 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 271
AS + L+ G +P +GLGT+ + +PG + VK+AL GYR ID AA+Y NE
Sbjct: 3 ASCVLLHTGQKMPLIGLGTW---------KSEPGQVKAAVKYALSVGYRHIDCAAIYGNE 53
Query: 272 DQIGAAVR-----ASGIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIH 430
+IG A++ +PRE++F+ +KL + DV L K+LA L + Y+DLYL+H
Sbjct: 54 PEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMH 113
Query: 431 NPVAF----NP------GFKGFDIVDYLDTWKGM 502
P AF NP G +D Y +TWK +
Sbjct: 114 WPYAFERGDNPFPKNADGTICYDSTHYKETWKAL 147
>AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto
reductase protein.
Length = 130
Score = 83.8 bits (198), Expect = 5e-16
Identities = 51/124 (41%), Positives = 73/124 (58%), Gaps = 6/124 (4%)
Frame = +2
Query: 101 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 280
+ LNDG +P LG GT + ++V + E+ V+ A++ GYR ID+A +LNE+ I
Sbjct: 9 VKLNDGKFMPILGFGTSVA------RKVAMSNVEEAVQVAIDVGYRHIDSAYTHLNEEGI 62
Query: 281 GAAVR---ASG-IPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVA 442
G A+R A+G + R+DIF TK+ V + LE SL +L +SY+DLYL H PV
Sbjct: 63 GQAIRKKIANGTVKRKDIFYTTKVWGTFSRPELVQRGLEMSLKKLQLSYMDLYLFHFPVP 122
Query: 443 FNPG 454
PG
Sbjct: 123 LQPG 126
>AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 74.5 bits (175), Expect = 3e-13
Identities = 62/208 (29%), Positives = 106/208 (50%), Gaps = 9/208 (4%)
Frame = +2
Query: 89 KASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN 268
++ + LNDG +P LG GT+ + + K A++ G+R ID+A LY N
Sbjct: 7 QSHSVRLNDGPFMPVLGFGTY------APDHTPKSQAAEATKVAIDVGFRHIDSAYLYQN 60
Query: 269 EDQIGAAV---RASG-IPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIH 430
E+++G A+ A G + RE+IF KL V LE+SL +L YVDL++IH
Sbjct: 61 EEEVGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIH 120
Query: 431 NPVAFNPGFKGFDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG--QIKPS 604
P A G +++ ++A + +++ + +T +++ IL + KP+
Sbjct: 121 VPFAMKQ--PGKELLP--------KDASGEIILETVELC--DTWELELILNKPGLRYKPT 168
Query: 605 VLQ-VEVNLHLGQDKLIDYCKRNGIVVM 685
Q VE + +L Q KL+++CK IV++
Sbjct: 169 CNQVVECHPYLNQSKLLEFCKSKDIVLV 196
>AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 74.5 bits (175), Expect = 3e-13
Identities = 62/208 (29%), Positives = 106/208 (50%), Gaps = 9/208 (4%)
Frame = +2
Query: 89 KASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN 268
++ + LNDG +P LG GT+ + + K A++ G+R ID+A LY N
Sbjct: 7 QSHSVRLNDGPFMPVLGFGTY------APDHTPKSQAAEATKVAIDVGFRHIDSAYLYQN 60
Query: 269 EDQIGAAV---RASG-IPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIH 430
E+++G A+ A G + RE+IF KL V LE+SL +L YVDL++IH
Sbjct: 61 EEEVGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIH 120
Query: 431 NPVAFNPGFKGFDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG--QIKPS 604
P A G +++ ++A + +++ + +T +++ IL + KP+
Sbjct: 121 VPFAMKQ--PGKELLP--------KDASGEIILETVELC--DTWELELILNKPGLRYKPT 168
Query: 605 VLQ-VEVNLHLGQDKLIDYCKRNGIVVM 685
Q VE + +L Q KL+++CK IV++
Sbjct: 169 CNQVVECHPYLNQSKLLEFCKSKDIVLV 196
>AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase
related protein 3 protein.
Length = 222
Score = 72.1 bits (169), Expect = 2e-12
Identities = 45/115 (39%), Positives = 66/115 (57%), Gaps = 6/115 (5%)
Frame = +2
Query: 125 IPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGAAVRA-- 298
IPA+GL ++ + PG + VK A++AGYR D A Y NE ++GA +R
Sbjct: 4 IPAVGLSSW---------KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKI 54
Query: 299 --SGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHNPVAFNP 451
+ RED+FI TKL +++ +V+ KSL L ++Y+DLYLIH P+ F P
Sbjct: 55 KEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKP 109
>BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 67.3 bits (157), Expect = 5e-11
Identities = 44/124 (35%), Positives = 65/124 (52%), Gaps = 6/124 (4%)
Frame = +2
Query: 89 KASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN 268
++ + LNDG +P LG GT+ + + K A++ G+R ID+A LY N
Sbjct: 7 QSHSVRLNDGPFMPVLGFGTY------APDHTPKSQAAEATKVAIDVGFRHIDSAYLYQN 60
Query: 269 EDQIGAAV---RASG-IPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIH 430
E+++G A+ A G + RE+IF KL V LE+SL +L YVDL++IH
Sbjct: 61 EEEVGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIH 120
Query: 431 NPVA 442
P A
Sbjct: 121 VPFA 124
>BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 67.3 bits (157), Expect = 5e-11
Identities = 44/124 (35%), Positives = 65/124 (52%), Gaps = 6/124 (4%)
Frame = +2
Query: 89 KASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN 268
++ + LNDG +P LG GT+ + + K A++ G+R ID+A LY N
Sbjct: 7 QSHSVRLNDGPFMPVLGFGTY------APDHTPKSQAAEATKVAIDVGFRHIDSAYLYQN 60
Query: 269 EDQIGAAV---RASG-IPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIH 430
E+++G A+ A G + RE+IF KL V LE+SL +L YVDL++IH
Sbjct: 61 EEEVGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIH 120
Query: 431 NPVA 442
P A
Sbjct: 121 VPFA 124
>AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens
cDNA FLJ16347 fis, clone TESTI2036288, moderately
similar to PROSTAGLANDIN-F SYNTHASE 1 (EC 1.1.1.188). ).
Length = 129
Score = 67.3 bits (157), Expect = 5e-11
Identities = 44/124 (35%), Positives = 65/124 (52%), Gaps = 6/124 (4%)
Frame = +2
Query: 89 KASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN 268
++ + LNDG +P LG GT+ + + K A++ G+R ID+A LY N
Sbjct: 7 QSHSVRLNDGPFMPVLGFGTY------APDHTPKSQAAEATKVAIDVGFRHIDSAYLYQN 60
Query: 269 EDQIGAAV---RASG-IPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIH 430
E+++G A+ A G + RE+IF KL V LE+SL +L YVDL++IH
Sbjct: 61 EEEVGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIH 120
Query: 431 NPVA 442
P A
Sbjct: 121 VPFA 124
>AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens
cDNA FLJ25413 fis, clone TST03402, highly similar to
3-OXO-5-BETA-STEROID 4-DEHYDROGENASE (EC 1.3.99.6). ).
Length = 146
Score = 58.8 bits (136), Expect = 2e-08
Identities = 28/67 (41%), Positives = 43/67 (64%), Gaps = 2/67 (2%)
Frame = +2
Query: 488 TWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQI--KPSVLQVEVNLHLGQDKLIDYC 661
TW+ ME K+ GL KS+G+SNFN Q++ IL + KP QVE + + Q KL+ +C
Sbjct: 28 TWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFC 87
Query: 662 KRNGIVV 682
+++ IV+
Sbjct: 88 QQHDIVI 94
>AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthase
protein.
Length = 67
Score = 56.8 bits (131), Expect = 7e-08
Identities = 25/45 (55%), Positives = 32/45 (71%)
Frame = +2
Query: 464 FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIK 598
FDIVD TW+ ME+ K+ GLAKSIG+SNFN Q++ IL +K
Sbjct: 16 FDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLK 60
>U16953-1|AAC50122.1| 408|Homo sapiens potassium channel beta3
subunit protein.
Length = 408
Score = 46.4 bits (105), Expect = 9e-05
Identities = 41/145 (28%), Positives = 68/145 (46%), Gaps = 13/145 (8%)
Frame = +2
Query: 56 VHLSEATTGG-GKASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAG 232
+ L E T G A + G + LGLGT++ F + EV +E+ + A E+G
Sbjct: 66 ISLQETTRAETGMAYRNLGKSGLRVSCLGLGTWVTFGGQISDEV----AERLMTIAYESG 121
Query: 233 YRLIDTAALYL---NEDQIGAAVRASGIPREDIFIVTKLPMD---------NQRDVVKQL 376
L DTA +Y E +G+ ++ G R + I TKL +++ +++ L
Sbjct: 122 VNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGL 181
Query: 377 EKSLARLNMSYVDLYLIHNPVAFNP 451
+ SL RL + YVD+ + P + P
Sbjct: 182 KGSLQRLQLEYVDVVFANRPDSNTP 206
>L39833-1|AAC37573.1| 408|Homo sapiens K+ channel beta-subunit
protein.
Length = 408
Score = 46.4 bits (105), Expect = 9e-05
Identities = 41/145 (28%), Positives = 68/145 (46%), Gaps = 13/145 (8%)
Frame = +2
Query: 56 VHLSEATTGG-GKASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAG 232
+ L E T G A + G + LGLGT++ F + EV +E+ + A E+G
Sbjct: 66 ISLQETTRAETGMAYRNLGKSGLRVSCLGLGTWVTFGGQISDEV----AERLMTIAYESG 121
Query: 233 YRLIDTAALYL---NEDQIGAAVRASGIPREDIFIVTKLPMD---------NQRDVVKQL 376
L DTA +Y E +G+ ++ G R + I TKL +++ +++ L
Sbjct: 122 VNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGL 181
Query: 377 EKSLARLNMSYVDLYLIHNPVAFNP 451
+ SL RL + YVD+ + P + P
Sbjct: 182 KGSLQRLQLEYVDVVFANRPDSNTP 206
>X83127-1|CAA58208.1| 401|Homo sapiens voltage gated potassium
channels, beta subunit protein.
Length = 401
Score = 45.6 bits (103), Expect = 2e-04
Identities = 36/124 (29%), Positives = 61/124 (49%), Gaps = 12/124 (9%)
Frame = +2
Query: 116 GNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYL---NEDQIGA 286
G + LGLGT++ F + EV +E+ + A E+G L DTA +Y E +G+
Sbjct: 80 GLRVSCLGLGTWVTFGGQISDEV----AERLMTIAYESGVNLFDTAEVYAAGKAEVILGS 135
Query: 287 AVRASGIPREDIFIVTKLPMD---------NQRDVVKQLEKSLARLNMSYVDLYLIHNPV 439
++ G R + I TKL +++ +++ L+ SL RL + YVD+ + P
Sbjct: 136 IIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPD 195
Query: 440 AFNP 451
+ P
Sbjct: 196 SNTP 199
>U33428-1|AAC50953.1| 401|Homo sapiens K+ channel beta 1a subunit
protein.
Length = 401
Score = 45.6 bits (103), Expect = 2e-04
Identities = 36/124 (29%), Positives = 61/124 (49%), Gaps = 12/124 (9%)
Frame = +2
Query: 116 GNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYL---NEDQIGA 286
G + LGLGT++ F + EV +E+ + A E+G L DTA +Y E +G+
Sbjct: 80 GLRVSCLGLGTWVTFGGQISDEV----AERLMTIAYESGVNLFDTAEVYAAGKAEVILGS 135
Query: 287 AVRASGIPREDIFIVTKLPMD---------NQRDVVKQLEKSLARLNMSYVDLYLIHNPV 439
++ G R + I TKL +++ +++ L+ SL RL + YVD+ + P
Sbjct: 136 IIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPD 195
Query: 440 AFNP 451
+ P
Sbjct: 196 SNTP 199
>L47665-1|AAC41926.1| 419|Homo sapiens K+ channel beta-subunit
protein.
Length = 419
Score = 45.6 bits (103), Expect = 2e-04
Identities = 36/124 (29%), Positives = 61/124 (49%), Gaps = 12/124 (9%)
Frame = +2
Query: 116 GNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYL---NEDQIGA 286
G + LGLGT++ F + EV +E+ + A E+G L DTA +Y E +G+
Sbjct: 98 GLRVSCLGLGTWVTFGGQISDEV----AERLMTIAYESGVNLFDTAEVYAAGKAEVILGS 153
Query: 287 AVRASGIPREDIFIVTKLPMD---------NQRDVVKQLEKSLARLNMSYVDLYLIHNPV 439
++ G R + I TKL +++ +++ L+ SL RL + YVD+ + P
Sbjct: 154 IIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPD 213
Query: 440 AFNP 451
+ P
Sbjct: 214 SNTP 217
>BC043166-1|AAH43166.1| 401|Homo sapiens potassium voltage-gated
channel, shaker-related subfamily, beta member 1
protein.
Length = 401
Score = 45.6 bits (103), Expect = 2e-04
Identities = 36/124 (29%), Positives = 61/124 (49%), Gaps = 12/124 (9%)
Frame = +2
Query: 116 GNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYL---NEDQIGA 286
G + LGLGT++ F + EV +E+ + A E+G L DTA +Y E +G+
Sbjct: 80 GLRVSCLGLGTWVTFGGQISDEV----AERLMTIAYESGVNLFDTAEVYAAGKAEVILGS 135
Query: 287 AVRASGIPREDIFIVTKLPMD---------NQRDVVKQLEKSLARLNMSYVDLYLIHNPV 439
++ G R + I TKL +++ +++ L+ SL RL + YVD+ + P
Sbjct: 136 IIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPD 195
Query: 440 AFNP 451
+ P
Sbjct: 196 SNTP 199
>AF026947-1|AAC52104.1| 330|Homo sapiens aflatoxin aldehyde
reductase AFAR protein.
Length = 330
Score = 39.5 bits (88), Expect = 0.011
Identities = 50/174 (28%), Positives = 74/174 (42%), Gaps = 12/174 (6%)
Frame = +2
Query: 128 PALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN---EDQIGAAVRA 298
P + + LG E G++ P S V+ LE G+ +DTA +Y + E +G
Sbjct: 5 PPPRVASVLGTMEMGRRMDAPA-SAAAVRAFLERGHTELDTAFMYSDGQSETILGGLGLG 63
Query: 299 SGIPREDIFIVTKL-PMDNQR----DVVKQLEKSLARLNMSYVDLYLIHNPVAFNPGFKG 463
G + I TK P D + V QLE SL RL VDL+ +H P P
Sbjct: 64 LGGGDCRVKIATKANPWDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHTPDHGTP---- 119
Query: 464 FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL----ENGQIKPSVLQ 613
V+ +T + G +G+SN+ + ++ I NG I P+V Q
Sbjct: 120 ---VE--ETLHACQRLHQEGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQ 168
>Y16675-1|CAA76347.1| 330|Homo sapiens aflatoxin B1-aldehyde
reductase protein.
Length = 330
Score = 38.7 bits (86), Expect = 0.019
Identities = 50/174 (28%), Positives = 74/174 (42%), Gaps = 12/174 (6%)
Frame = +2
Query: 128 PALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN---EDQIGAAVRA 298
P + + LG E G++ P S V+ LE G+ +DTA +Y + E +G
Sbjct: 5 PPPRVASVLGTMEMGRRMDAPA-SAAAVRAFLERGHTELDTAFMYSDGQSETILGGLGLG 63
Query: 299 SGIPREDIFIVTKL-PMDNQR----DVVKQLEKSLARLNMSYVDLYLIHNPVAFNPGFKG 463
G + I TK P D + V QLE SL RL VDL+ +H P P
Sbjct: 64 LGGGDCRVKIATKANPWDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHAPDHGTP---- 119
Query: 464 FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL----ENGQIKPSVLQ 613
V+ +T + G +G+SN+ + ++ I NG I P+V Q
Sbjct: 120 ---VE--ETLHACQRLHQEGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQ 168
>BT007347-1|AAP36011.1| 330|Homo sapiens aldo-keto reductase family
7, member A2 (aflatoxin aldehyde reductase) protein.
Length = 330
Score = 38.7 bits (86), Expect = 0.019
Identities = 50/174 (28%), Positives = 74/174 (42%), Gaps = 12/174 (6%)
Frame = +2
Query: 128 PALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN---EDQIGAAVRA 298
P + + LG E G++ P S V+ LE G+ +DTA +Y + E +G
Sbjct: 5 PPPRVASVLGTMEMGRRMDAPA-SAAAVRAFLERGHTELDTAFMYSDGQSETILGGLGLG 63
Query: 299 SGIPREDIFIVTKL-PMDNQR----DVVKQLEKSLARLNMSYVDLYLIHNPVAFNPGFKG 463
G + I TK P D + V QLE SL RL VDL+ +H P P
Sbjct: 64 LGGGDCRVKIATKANPWDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHAPDHGTP---- 119
Query: 464 FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL----ENGQIKPSVLQ 613
V+ +T + G +G+SN+ + ++ I NG I P+V Q
Sbjct: 120 ---VE--ETLHACQRLHQEGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQ 168
>BC013996-1|AAH13996.1| 330|Homo sapiens AKR7A2 protein protein.
Length = 330
Score = 38.7 bits (86), Expect = 0.019
Identities = 50/174 (28%), Positives = 74/174 (42%), Gaps = 12/174 (6%)
Frame = +2
Query: 128 PALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN---EDQIGAAVRA 298
P + + LG E G++ P S V+ LE G+ +DTA +Y + E +G
Sbjct: 5 PPPRVASVLGTMEMGRRMDAPA-SAAAVRAFLERGHTELDTAFMYSDGQSETILGGLGLG 63
Query: 299 SGIPREDIFIVTKL-PMDNQR----DVVKQLEKSLARLNMSYVDLYLIHNPVAFNPGFKG 463
G + I TK P D + V QLE SL RL VDL+ +H P P
Sbjct: 64 LGGGDCRVKIATKANPWDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHAPDHGTP---- 119
Query: 464 FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL----ENGQIKPSVLQ 613
V+ +T + G +G+SN+ + ++ I NG I P+V Q
Sbjct: 120 ---VE--ETLHACQRLHQEGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQ 168
>BC012171-1|AAH12171.1| 330|Homo sapiens AKR7A2 protein protein.
Length = 330
Score = 38.7 bits (86), Expect = 0.019
Identities = 50/174 (28%), Positives = 74/174 (42%), Gaps = 12/174 (6%)
Frame = +2
Query: 128 PALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN---EDQIGAAVRA 298
P + + LG E G++ P S V+ LE G+ +DTA +Y + E +G
Sbjct: 5 PPPRVASVLGTMEMGRRMDAPA-SAAAVRAFLERGHTELDTAFMYSDGQSETILGGLGLG 63
Query: 299 SGIPREDIFIVTKL-PMDNQR----DVVKQLEKSLARLNMSYVDLYLIHNPVAFNPGFKG 463
G + I TK P D + V QLE SL RL VDL+ +H P P
Sbjct: 64 LGGGDCRVKIATKANPWDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHAPDHGTP---- 119
Query: 464 FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL----ENGQIKPSVLQ 613
V+ +T + G +G+SN+ + ++ I NG I P+V Q
Sbjct: 120 ---VE--ETLHACQRLHQEGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQ 168
>BC011586-1|AAH11586.1| 330|Homo sapiens AKR7A2 protein protein.
Length = 330
Score = 38.7 bits (86), Expect = 0.019
Identities = 50/174 (28%), Positives = 74/174 (42%), Gaps = 12/174 (6%)
Frame = +2
Query: 128 PALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN---EDQIGAAVRA 298
P + + LG E G++ P S V+ LE G+ +DTA +Y + E +G
Sbjct: 5 PPPRVASVLGTMEMGRRMDAPA-SAAAVRAFLERGHTELDTAFMYSDGQSETILGGLGLG 63
Query: 299 SGIPREDIFIVTKL-PMDNQR----DVVKQLEKSLARLNMSYVDLYLIHNPVAFNPGFKG 463
G + I TK P D + V QLE SL RL VDL+ +H P P
Sbjct: 64 LGGGDCRVKIATKANPWDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHAPDHGTP---- 119
Query: 464 FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL----ENGQIKPSVLQ 613
V+ +T + G +G+SN+ + ++ I NG I P+V Q
Sbjct: 120 ---VE--ETLHACQRLHQEGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQ 168
>BC010852-1|AAH10852.1| 330|Homo sapiens AKR7A2 protein protein.
Length = 330
Score = 38.7 bits (86), Expect = 0.019
Identities = 50/174 (28%), Positives = 74/174 (42%), Gaps = 12/174 (6%)
Frame = +2
Query: 128 PALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN---EDQIGAAVRA 298
P + + LG E G++ P S V+ LE G+ +DTA +Y + E +G
Sbjct: 5 PPPRVASVLGTMEMGRRMDAPA-SAAAVRAFLERGHTELDTAFMYSDGQSETILGGLGLG 63
Query: 299 SGIPREDIFIVTKL-PMDNQR----DVVKQLEKSLARLNMSYVDLYLIHNPVAFNPGFKG 463
G + I TK P D + V QLE SL RL VDL+ +H P P
Sbjct: 64 LGGGDCRVKIATKANPWDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHAPDHGTP---- 119
Query: 464 FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL----ENGQIKPSVLQ 613
V+ +T + G +G+SN+ + ++ I NG I P+V Q
Sbjct: 120 ---VE--ETLHACQRLHQEGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQ 168
>BC007352-1|AAH07352.2| 358|Homo sapiens AKR7A2 protein protein.
Length = 358
Score = 38.7 bits (86), Expect = 0.019
Identities = 50/174 (28%), Positives = 74/174 (42%), Gaps = 12/174 (6%)
Frame = +2
Query: 128 PALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN---EDQIGAAVRA 298
P + + LG E G++ P S V+ LE G+ +DTA +Y + E +G
Sbjct: 33 PPPRVASVLGTMEMGRRMDAPA-SAAAVRAFLERGHTELDTAFMYSDGQSETILGGLGLG 91
Query: 299 SGIPREDIFIVTKL-PMDNQR----DVVKQLEKSLARLNMSYVDLYLIHNPVAFNPGFKG 463
G + I TK P D + V QLE SL RL VDL+ +H P P
Sbjct: 92 LGGGDCRVKIATKANPWDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHAPDHGTP---- 147
Query: 464 FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL----ENGQIKPSVLQ 613
V+ +T + G +G+SN+ + ++ I NG I P+V Q
Sbjct: 148 ---VE--ETLHACQRLHQEGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQ 196
>BC004111-1|AAH04111.3| 330|Homo sapiens AKR7A2 protein protein.
Length = 330
Score = 38.7 bits (86), Expect = 0.019
Identities = 50/174 (28%), Positives = 74/174 (42%), Gaps = 12/174 (6%)
Frame = +2
Query: 128 PALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN---EDQIGAAVRA 298
P + + LG E G++ P S V+ LE G+ +DTA +Y + E +G
Sbjct: 5 PPPRVASVLGTMEMGRRMDAPA-SAAAVRAFLERGHTELDTAFMYSDGQSETILGGLGLG 63
Query: 299 SGIPREDIFIVTKL-PMDNQR----DVVKQLEKSLARLNMSYVDLYLIHNPVAFNPGFKG 463
G + I TK P D + V QLE SL RL VDL+ +H P P
Sbjct: 64 LGGGDCRVKIATKANPWDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHAPDHGTP---- 119
Query: 464 FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL----ENGQIKPSVLQ 613
V+ +T + G +G+SN+ + ++ I NG I P+V Q
Sbjct: 120 ---VE--ETLHACQRLHQEGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQ 168
>AL035413-8|CAB72321.1| 330|Homo sapiens aldo-keto reductase family
7, member A2 (aflatoxin aldehyde reductase) protein.
Length = 330
Score = 38.7 bits (86), Expect = 0.019
Identities = 50/174 (28%), Positives = 74/174 (42%), Gaps = 12/174 (6%)
Frame = +2
Query: 128 PALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN---EDQIGAAVRA 298
P + + LG E G++ P S V+ LE G+ +DTA +Y + E +G
Sbjct: 5 PPPRVASVLGTMEMGRRMDAPA-SAAAVRAFLERGHTELDTAFMYSDGQSETILGGLGLG 63
Query: 299 SGIPREDIFIVTKL-PMDNQR----DVVKQLEKSLARLNMSYVDLYLIHNPVAFNPGFKG 463
G + I TK P D + V QLE SL RL VDL+ +H P P
Sbjct: 64 LGGGDCRVKIATKANPWDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHAPDHGTP---- 119
Query: 464 FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL----ENGQIKPSVLQ 613
V+ +T + G +G+SN+ + ++ I NG I P+V Q
Sbjct: 120 ---VE--ETLHACQRLHQEGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQ 168
>AB037905-2|BAA92890.1| 45|Homo sapiens truncated aldo-keto
reductase protein.
Length = 45
Score = 38.7 bits (86), Expect = 0.019
Identities = 17/31 (54%), Positives = 21/31 (67%)
Frame = +2
Query: 362 VVKQLEKSLARLNMSYVDLYLIHNPVAFNPG 454
V + LE SL +L +SY+DLYL H PV PG
Sbjct: 11 VQRGLEMSLKKLQLSYMDLYLFHFPVPLQPG 41
>AY780786-1|AAV98356.1| 372|Homo sapiens potassium voltage-gated
channel beta subunit protein.
Length = 372
Score = 36.7 bits (81), Expect = 0.077
Identities = 27/92 (29%), Positives = 45/92 (48%), Gaps = 3/92 (3%)
Frame = +2
Query: 116 GNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYL---NEDQIGA 286
G + LGLGT++ F + EV +E+ + A E+G L DTA +Y E +G+
Sbjct: 80 GLRVSCLGLGTWVTFGGQISDEV----AERLMTIAYESGVNLFDTAEVYAAGKAEVILGS 135
Query: 287 AVRASGIPREDIFIVTKLPMDNQRDVVKQLEK 382
++ G R + I TKL + + + L +
Sbjct: 136 IIKKKGWRRSSLVITTKLYWGGKAETERGLSR 167
>BC042420-1|AAH42420.2| 331|Homo sapiens aldo-keto reductase family
7, member A3 (aflatoxin aldehyde reductase) protein.
Length = 331
Score = 34.7 bits (76), Expect = 0.31
Identities = 49/168 (29%), Positives = 73/168 (43%), Gaps = 12/168 (7%)
Frame = +2
Query: 146 TFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYL---NEDQIGAAVRASGIPRE 316
T LG E G++ P S + LE G+ IDTA +Y +E +G G
Sbjct: 12 TVLGAMEMGRRMDAP-TSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDC 70
Query: 317 DIFIVTK-LPMDNQR---DVVK-QLEKSLARLNMSYVDLYLIHNPVAFNPGFKGFDIVDY 481
+ I TK +P+ D ++ QLE SL RL VDL+ +H P P V+
Sbjct: 71 RVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTP-------VE- 122
Query: 482 LDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL----ENGQIKPSVLQ 613
+T + + G +G+SN+ ++ I NG I P+V Q
Sbjct: 123 -ETLRACHQLHQEGKFMELGLSNYAAWEVAEICTLCKSNGWILPTVYQ 169
>BC031562-1|AAH31562.1| 331|Homo sapiens aldo-keto reductase family
7, member A3 (aflatoxin aldehyde reductase) protein.
Length = 331
Score = 34.7 bits (76), Expect = 0.31
Identities = 49/168 (29%), Positives = 73/168 (43%), Gaps = 12/168 (7%)
Frame = +2
Query: 146 TFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYL---NEDQIGAAVRASGIPRE 316
T LG E G++ P S + LE G+ IDTA +Y +E +G G
Sbjct: 12 TVLGAMEMGRRMDAP-TSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDC 70
Query: 317 DIFIVTK-LPMDNQR---DVVK-QLEKSLARLNMSYVDLYLIHNPVAFNPGFKGFDIVDY 481
+ I TK +P+ D ++ QLE SL RL VDL+ +H P P V+
Sbjct: 71 RVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTP-------VE- 122
Query: 482 LDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL----ENGQIKPSVLQ 613
+T + + G +G+SN+ ++ I NG I P+V Q
Sbjct: 123 -ETLRACHQLHQEGKFMELGLSNYAAWEVAEICTLCKSNGWILPTVYQ 169
>AJ271799-1|CAC81076.1| 331|Homo sapiens aflatoxin B1 aldehyde
reductase 2 protein.
Length = 331
Score = 34.7 bits (76), Expect = 0.31
Identities = 49/168 (29%), Positives = 73/168 (43%), Gaps = 12/168 (7%)
Frame = +2
Query: 146 TFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYL---NEDQIGAAVRASGIPRE 316
T LG E G++ P S + LE G+ IDTA +Y +E +G G
Sbjct: 12 TVLGAMEMGRRMDAP-TSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDC 70
Query: 317 DIFIVTK-LPMDNQR---DVVK-QLEKSLARLNMSYVDLYLIHNPVAFNPGFKGFDIVDY 481
+ I TK +P+ D ++ QLE SL RL VDL+ +H P P V+
Sbjct: 71 RVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTP-------VE- 122
Query: 482 LDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL----ENGQIKPSVLQ 613
+T + + G +G+SN+ ++ I NG I P+V Q
Sbjct: 123 -ETLRACHQLHQEGKFMELGLSNYAAWEVAEICTLCKSNGWILPTVYQ 169
>AF040639-1|AAD02195.1| 331|Homo sapiens aflatoxin B1-aldehyde
reductase protein.
Length = 331
Score = 34.7 bits (76), Expect = 0.31
Identities = 49/168 (29%), Positives = 73/168 (43%), Gaps = 12/168 (7%)
Frame = +2
Query: 146 TFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN---EDQIGAAVRASGIPRE 316
T LG E G++ P S + LE G+ IDTA +Y + E +G G
Sbjct: 12 TVLGAMEMGRRMDAP-TSAAVTRAFLERGHTEIDTAFVYSDGQSETILGGLGLRLGGSDC 70
Query: 317 DIFIVTK-LPMDNQR---DVVK-QLEKSLARLNMSYVDLYLIHNPVAFNPGFKGFDIVDY 481
+ I TK +P+ D ++ QLE SL RL VDL+ +H P P V+
Sbjct: 71 RVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTP-------VE- 122
Query: 482 LDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL----ENGQIKPSVLQ 613
+T + + G +G+SN+ ++ I NG I P+V Q
Sbjct: 123 -ETLRACHQLHQEGKFMELGLSNYAAWEVAEICTLCKSNGWILPTVYQ 169
>BC025709-1|AAH25709.1| 331|Homo sapiens aldo-keto reductase family
7, member A3 (aflatoxin aldehyde reductase) protein.
Length = 331
Score = 34.3 bits (75), Expect = 0.41
Identities = 49/168 (29%), Positives = 73/168 (43%), Gaps = 12/168 (7%)
Frame = +2
Query: 146 TFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYL---NEDQIGAAVRASGIPRE 316
T LG E G++ P S + LE G+ IDTA +Y +E +G G
Sbjct: 12 TVLGAMEMGRRMDAP-TSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDC 70
Query: 317 DIFIVTK-LPMDNQR---DVVK-QLEKSLARLNMSYVDLYLIHNPVAFNPGFKGFDIVDY 481
+ I TK +P+ D ++ QLE SL RL VDL+ +H P P V+
Sbjct: 71 RVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTP-------VE- 122
Query: 482 LDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL----ENGQIKPSVLQ 613
+T + + G +G+SN+ ++ I NG I P+V Q
Sbjct: 123 -ETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQ 169
>AL035413-11|CAI22232.1| 331|Homo sapiens aldo-keto reductase
family 7, member A3 (aflatoxin aldehyde reductase)
protein.
Length = 331
Score = 34.3 bits (75), Expect = 0.41
Identities = 49/168 (29%), Positives = 73/168 (43%), Gaps = 12/168 (7%)
Frame = +2
Query: 146 TFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYL---NEDQIGAAVRASGIPRE 316
T LG E G++ P S + LE G+ IDTA +Y +E +G G
Sbjct: 12 TVLGAMEMGRRMDAP-TSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDC 70
Query: 317 DIFIVTK-LPMDNQR---DVVK-QLEKSLARLNMSYVDLYLIHNPVAFNPGFKGFDIVDY 481
+ I TK +P+ D ++ QLE SL RL VDL+ +H P P V+
Sbjct: 71 RVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTP-------VE- 122
Query: 482 LDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL----ENGQIKPSVLQ 613
+T + + G +G+SN+ ++ I NG I P+V Q
Sbjct: 123 -ETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQ 169
>BX537840-1|CAD97851.1| 2150|Homo sapiens hypothetical protein
protein.
Length = 2150
Score = 32.3 bits (70), Expect = 1.7
Identities = 27/89 (30%), Positives = 40/89 (44%), Gaps = 1/89 (1%)
Frame = +2
Query: 242 IDTAALYLNEDQIGAAVRASGIPREDI-FIVTKLPMDNQRDVVKQLEKSLARLNMSYVDL 418
IDT L + DQ V +E I FI L N V++L++++ M +V
Sbjct: 1070 IDT--LLVATDQTERIVEPPENIQEKIAFIFNNLSQSNMTQKVEELKETVKEEFMPWVSQ 1127
Query: 419 YLIHNPVAFNPGFKGFDIVDYLDTWKGME 505
YL+ V+ P F ++LDT K E
Sbjct: 1128 YLVMKRVSIEPNFHSL-YSNFLDTLKNPE 1155
>BC040523-1|AAH40523.1| 1551|Homo sapiens CCR4-NOT transcription
complex, subunit 1 protein.
Length = 1551
Score = 32.3 bits (70), Expect = 1.7
Identities = 27/89 (30%), Positives = 40/89 (44%), Gaps = 1/89 (1%)
Frame = +2
Query: 242 IDTAALYLNEDQIGAAVRASGIPREDI-FIVTKLPMDNQRDVVKQLEKSLARLNMSYVDL 418
IDT L + DQ V +E I FI L N V++L++++ M +V
Sbjct: 1075 IDT--LLVATDQTERIVEPPENIQEKIAFIFNNLSQSNMTQKVEELKETVKEEFMPWVSQ 1132
Query: 419 YLIHNPVAFNPGFKGFDIVDYLDTWKGME 505
YL+ V+ P F ++LDT K E
Sbjct: 1133 YLVMKRVSIEPNFHSL-YSNFLDTLKNPE 1160
>BC024317-1|AAH24317.1| 1620|Homo sapiens CNOT1 protein protein.
Length = 1620
Score = 32.3 bits (70), Expect = 1.7
Identities = 27/89 (30%), Positives = 40/89 (44%), Gaps = 1/89 (1%)
Frame = +2
Query: 242 IDTAALYLNEDQIGAAVRASGIPREDI-FIVTKLPMDNQRDVVKQLEKSLARLNMSYVDL 418
IDT L + DQ V +E I FI L N V++L++++ M +V
Sbjct: 319 IDT--LLVATDQTERIVEPPENIQEKIAFIFNNLSQSNMTQKVEELKETVKEEFMPWVSQ 376
Query: 419 YLIHNPVAFNPGFKGFDIVDYLDTWKGME 505
YL+ V+ P F ++LDT K E
Sbjct: 377 YLVMKRVSIEPNFHSL-YSNFLDTLKNPE 404
>AB023224-1|BAA76851.2| 1835|Homo sapiens KIAA1007 protein protein.
Length = 1835
Score = 32.3 bits (70), Expect = 1.7
Identities = 27/89 (30%), Positives = 40/89 (44%), Gaps = 1/89 (1%)
Frame = +2
Query: 242 IDTAALYLNEDQIGAAVRASGIPREDI-FIVTKLPMDNQRDVVKQLEKSLARLNMSYVDL 418
IDT L + DQ V +E I FI L N V++L++++ M +V
Sbjct: 534 IDT--LLVATDQTERIVEPPENIQEKIAFIFNNLSQSNMTQKVEELKETVKEEFMPWVSQ 591
Query: 419 YLIHNPVAFNPGFKGFDIVDYLDTWKGME 505
YL+ V+ P F ++LDT K E
Sbjct: 592 YLVMKRVSIEPNFHSL-YSNFLDTLKNPE 619
>AM079206-1|CAL03352.1| 101|Homo sapiens immunoglobulin heavy chain
variable region protein.
Length = 101
Score = 31.9 bits (69), Expect = 2.2
Identities = 21/73 (28%), Positives = 30/73 (41%), Gaps = 4/73 (5%)
Frame = +2
Query: 461 GFDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQID----RILENGQIKPSVLQVEVNL 628
GF + Y TW K L SIGI N T D R + I S L ++++
Sbjct: 29 GFTLSSYAMTWVRQAPGKGLEWVSSIGIRNSGTYYADSVKGRFAISRDISRSTLYLQMDS 88
Query: 629 HLGQDKLIDYCKR 667
+D + YC +
Sbjct: 89 LRAEDTALYYCAK 101
>AJ278012-1|CAC79668.1| 259|Homo sapiens aflatoxin B1 aldehyde
reductase 3 protein.
Length = 259
Score = 30.3 bits (65), Expect = 6.7
Identities = 27/88 (30%), Positives = 39/88 (44%), Gaps = 4/88 (4%)
Frame = +2
Query: 362 VVKQLEKSLARLNMSYVDLYLIHNPVAFNPGFKGFDIVDYLDTWKGMEEAKNLGLAKSIG 541
V QLE SL RL VDL+ +H P P V+ +T + + G +G
Sbjct: 19 VRSQLETSLKRLQCPUVDLFYLHAPDHSAP-------VE--ETLRACHQLHQEGKFVELG 69
Query: 542 ISNFNTTQIDRIL----ENGQIKPSVLQ 613
+SN+ ++ I NG I P+V Q
Sbjct: 70 LSNYAAWEVAEICTLCKSNGWILPTVYQ 97
>AF471315-1|AAQ05490.1| 128|Homo sapiens Ig heavy chain variable
region, VH3 family protein.
Length = 128
Score = 30.3 bits (65), Expect = 6.7
Identities = 21/74 (28%), Positives = 30/74 (40%), Gaps = 4/74 (5%)
Frame = +2
Query: 461 GFDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHL-- 634
GF DY+ +W K L SI S NT D + I + V+L +
Sbjct: 26 GFTFDDYVMSWVRQAPGKELEWVASISGSAVNTYYADSVKGRFSISRDSFKNTVHLQMNG 85
Query: 635 --GQDKLIDYCKRN 670
G+D + YC R+
Sbjct: 86 LRGEDTALYYCARD 99
>Y13790-1|CAA74116.1| 123|Homo sapiens immunoglobulin heavy chain
variable and joining regions protein.
Length = 123
Score = 29.9 bits (64), Expect = 8.8
Identities = 21/76 (27%), Positives = 31/76 (40%), Gaps = 4/76 (5%)
Frame = +2
Query: 461 GFDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQID----RILENGQIKPSVLQVEVNL 628
GF DY +W K LGL I S T D R + + + L +++N
Sbjct: 26 GFTFSDYYMSWIRQAPGKGLGLISYITSSGHITYYADSVEGRFIISRDNAKNSLYLQMNT 85
Query: 629 HLGQDKLIDYCKRNGI 676
+D + YC R G+
Sbjct: 86 LRAEDTAVYYCARVGL 101
>U17968-1|AAC50113.1| 133|Homo sapiens voltage-gated potassium
channel beta subunit protein.
Length = 133
Score = 29.9 bits (64), Expect = 8.8
Identities = 23/70 (32%), Positives = 34/70 (48%), Gaps = 1/70 (1%)
Frame = +2
Query: 56 VHLSEATTGG-GKASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAG 232
+ L E T G A + G + LGLGT++ F + EV +E+ + A E+G
Sbjct: 63 ISLQETTRAETGMAYRNLGKSGLRVSCLGLGTWVTFGGQISDEV----AERLMTIAYESG 118
Query: 233 YRLIDTAALY 262
L DTA +Y
Sbjct: 119 VNLFDTAEVY 128
>AM082400-1|CAL06546.1| 101|Homo sapiens immunoglobulin heavy chain
variable region protein.
Length = 101
Score = 29.9 bits (64), Expect = 8.8
Identities = 20/73 (27%), Positives = 29/73 (39%), Gaps = 4/73 (5%)
Frame = +2
Query: 461 GFDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQID----RILENGQIKPSVLQVEVNL 628
GF + Y TW K L SI I+ NT D R + + L +++N
Sbjct: 29 GFSLSSYAMTWVRQAPGKGLEWVSSISITGANTYFADSVKGRFTVSRDSSKNTLYLQMNS 88
Query: 629 HLGQDKLIDYCKR 667
+D I YC +
Sbjct: 89 LRAEDTAIYYCAK 101
>AM079381-1|CAL03527.1| 100|Homo sapiens immunoglobulin heavy chain
variable region protein.
Length = 100
Score = 29.9 bits (64), Expect = 8.8
Identities = 19/71 (26%), Positives = 29/71 (40%), Gaps = 4/71 (5%)
Frame = +2
Query: 461 GFDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQID----RILENGQIKPSVLQVEVNL 628
GF +Y TW K L ++G + FNT D R + + L +E+N
Sbjct: 29 GFSFSNYAMTWVRQAPGKGLEWVSAVGSTGFNTFYADSVKGRFIISRDNFRDTLFLEMNS 88
Query: 629 HLGQDKLIDYC 661
+D + YC
Sbjct: 89 LRAEDTAVYYC 99
>AB066933-1|BAC01971.1| 129|Homo sapiens immunoglobulin heavy chain
VHDJ region protein.
Length = 129
Score = 29.9 bits (64), Expect = 8.8
Identities = 22/79 (27%), Positives = 32/79 (40%), Gaps = 4/79 (5%)
Frame = +2
Query: 461 GFDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTT--QI--DRILENGQIKPSVLQVEVNL 628
G+ Y W + L +I S TT QI R+ G S + +E++
Sbjct: 26 GYSFTTYYIHWVRQAPGQGLEWMGTINPSGDTTTYAQIFQGRVTMTGDTSTSTVYMELSS 85
Query: 629 HLGQDKLIDYCKRNGIVVM 685
+D + YC R IVVM
Sbjct: 86 LRSEDTAVYYCAREAIVVM 104
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 99,978,390
Number of Sequences: 237096
Number of extensions: 2070137
Number of successful extensions: 9572
Number of sequences better than 10.0: 128
Number of HSP's better than 10.0 without gapping: 9079
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 9240
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 7783251346
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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