Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmte26c23
(677 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BT007047-1|AAP35696.1| 360|Homo sapiens deoxyribonuclease II, l... 72 2e-12
BC065209-1|AAH65209.1| 360|Homo sapiens deoxyribonuclease II, l... 72 2e-12
BC010419-1|AAH10419.3| 360|Homo sapiens DNASE2 protein protein. 72 2e-12
AF060222-1|AAC39852.1| 360|Homo sapiens deoxyribonuclease II pr... 72 2e-12
AF047016-1|AAC77366.1| 360|Homo sapiens deoxyribonuclease II al... 72 2e-12
AF045937-1|AAC35751.1| 360|Homo sapiens deoxyribonuclease II pr... 72 2e-12
AD000092-2|AAB51172.1| 348|Homo sapiens hypothetical human prot... 72 2e-12
AB008564-1|BAB55598.1| 360|Homo sapiens deoxyribonuclease II pr... 72 2e-12
AB004574-1|BAA28623.1| 360|Homo sapiens deoxyribonuclease II pr... 72 2e-12
AL359273-6|CAH73126.1| 361|Homo sapiens deoxyribonuclease II be... 64 6e-10
AF334602-1|AAL34449.1| 361|Homo sapiens endonuclease DLAD protein. 64 6e-10
BC126138-1|AAI26139.2| 357|Homo sapiens deoxyribonuclease II be... 63 1e-09
BC126136-1|AAI26137.2| 357|Homo sapiens deoxyribonuclease II be... 63 1e-09
AF274571-1|AAF76893.1| 357|Homo sapiens deoxyribonuclease II be... 62 1e-09
BC080621-1|AAH80621.1| 251|Homo sapiens DNASE2B protein protein. 56 9e-08
>BT007047-1|AAP35696.1| 360|Homo sapiens deoxyribonuclease II,
lysosomal protein.
Length = 360
Score = 71.7 bits (168), Expect = 2e-12
Identities = 41/105 (39%), Positives = 55/105 (52%), Gaps = 2/105 (1%)
Frame = +3
Query: 39 LLKLFLFAFFINDSLCLTPQCRNEKGEPIDWFYVYKLPRERNHLNPLVRRGVAYMHLTPS 218
++ L L A + LT C + G+P+DWF VYKLP R +RG+ Y +L S
Sbjct: 1 MIPLLLAALLCVPAGALT--CYGDSGQPVDWFVVYKLPALRGS-GEAAQRGLQYKYLDES 57
Query: 219 KLRGGWIMSDLAISDPRSMVGRTLAPLYQD--KNIISLVYNDQPP 347
GGW I+ P VGR+L PLY+ + L+YNDQPP
Sbjct: 58 S--GGWRDGRALINSPEGAVGRSLQPLYRSNTSQLAFLLYNDQPP 100
Score = 43.6 bits (98), Expect = 7e-04
Identities = 18/26 (69%), Positives = 19/26 (73%)
Frame = +3
Query: 540 GHTKGVILGDKFTSLWLVHSVPRFPP 617
GHTKGV+L D WLVHSVP FPP
Sbjct: 112 GHTKGVLLLDHDGGFWLVHSVPNFPP 137
>BC065209-1|AAH65209.1| 360|Homo sapiens deoxyribonuclease II,
lysosomal protein.
Length = 360
Score = 71.7 bits (168), Expect = 2e-12
Identities = 41/105 (39%), Positives = 55/105 (52%), Gaps = 2/105 (1%)
Frame = +3
Query: 39 LLKLFLFAFFINDSLCLTPQCRNEKGEPIDWFYVYKLPRERNHLNPLVRRGVAYMHLTPS 218
++ L L A + LT C + G+P+DWF VYKLP R +RG+ Y +L S
Sbjct: 1 MIPLLLAALLCVPAGALT--CYGDSGQPVDWFVVYKLPALRGS-GEAAQRGLQYKYLDES 57
Query: 219 KLRGGWIMSDLAISDPRSMVGRTLAPLYQD--KNIISLVYNDQPP 347
GGW I+ P VGR+L PLY+ + L+YNDQPP
Sbjct: 58 S--GGWRDGRALINSPEGAVGRSLQPLYRSNTSQLAFLLYNDQPP 100
Score = 43.6 bits (98), Expect = 7e-04
Identities = 18/26 (69%), Positives = 19/26 (73%)
Frame = +3
Query: 540 GHTKGVILGDKFTSLWLVHSVPRFPP 617
GHTKGV+L D WLVHSVP FPP
Sbjct: 112 GHTKGVLLLDHDGGFWLVHSVPNFPP 137
>BC010419-1|AAH10419.3| 360|Homo sapiens DNASE2 protein protein.
Length = 360
Score = 71.7 bits (168), Expect = 2e-12
Identities = 41/105 (39%), Positives = 55/105 (52%), Gaps = 2/105 (1%)
Frame = +3
Query: 39 LLKLFLFAFFINDSLCLTPQCRNEKGEPIDWFYVYKLPRERNHLNPLVRRGVAYMHLTPS 218
++ L L A + LT C + G+P+DWF VYKLP R +RG+ Y +L S
Sbjct: 1 MIPLLLAALLCVPAGALT--CYGDSGQPVDWFVVYKLPALRGS-GEAAQRGLQYKYLDES 57
Query: 219 KLRGGWIMSDLAISDPRSMVGRTLAPLYQD--KNIISLVYNDQPP 347
GGW I+ P VGR+L PLY+ + L+YNDQPP
Sbjct: 58 S--GGWRDGRALINSPEGAVGRSLQPLYRSNTSQLAFLLYNDQPP 100
Score = 43.6 bits (98), Expect = 7e-04
Identities = 18/26 (69%), Positives = 19/26 (73%)
Frame = +3
Query: 540 GHTKGVILGDKFTSLWLVHSVPRFPP 617
GHTKGV+L D WLVHSVP FPP
Sbjct: 112 GHTKGVLLLDHDGGFWLVHSVPNFPP 137
>AF060222-1|AAC39852.1| 360|Homo sapiens deoxyribonuclease II
protein.
Length = 360
Score = 71.7 bits (168), Expect = 2e-12
Identities = 41/105 (39%), Positives = 55/105 (52%), Gaps = 2/105 (1%)
Frame = +3
Query: 39 LLKLFLFAFFINDSLCLTPQCRNEKGEPIDWFYVYKLPRERNHLNPLVRRGVAYMHLTPS 218
++ L L A + LT C + G+P+DWF VYKLP R +RG+ Y +L S
Sbjct: 1 MIPLLLAALLCVPAGALT--CYGDSGQPVDWFVVYKLPALRGS-GEAAQRGLQYKYLDES 57
Query: 219 KLRGGWIMSDLAISDPRSMVGRTLAPLYQD--KNIISLVYNDQPP 347
GGW I+ P VGR+L PLY+ + L+YNDQPP
Sbjct: 58 S--GGWRDGRALINSPEGAVGRSLQPLYRSNTSQLAFLLYNDQPP 100
Score = 43.6 bits (98), Expect = 7e-04
Identities = 18/26 (69%), Positives = 19/26 (73%)
Frame = +3
Query: 540 GHTKGVILGDKFTSLWLVHSVPRFPP 617
GHTKGV+L D WLVHSVP FPP
Sbjct: 112 GHTKGVLLLDHDGGFWLVHSVPNFPP 137
>AF047016-1|AAC77366.1| 360|Homo sapiens deoxyribonuclease II alpha
protein.
Length = 360
Score = 71.7 bits (168), Expect = 2e-12
Identities = 41/105 (39%), Positives = 55/105 (52%), Gaps = 2/105 (1%)
Frame = +3
Query: 39 LLKLFLFAFFINDSLCLTPQCRNEKGEPIDWFYVYKLPRERNHLNPLVRRGVAYMHLTPS 218
++ L L A + LT C + G+P+DWF VYKLP R +RG+ Y +L S
Sbjct: 1 MIPLLLAALLCVPAGALT--CYGDSGQPVDWFVVYKLPALRGS-GEAAQRGLQYKYLDES 57
Query: 219 KLRGGWIMSDLAISDPRSMVGRTLAPLYQD--KNIISLVYNDQPP 347
GGW I+ P VGR+L PLY+ + L+YNDQPP
Sbjct: 58 S--GGWRDGRALINSPEGAVGRSLQPLYRSNTSQLAFLLYNDQPP 100
Score = 43.6 bits (98), Expect = 7e-04
Identities = 18/26 (69%), Positives = 19/26 (73%)
Frame = +3
Query: 540 GHTKGVILGDKFTSLWLVHSVPRFPP 617
GHTKGV+L D WLVHSVP FPP
Sbjct: 112 GHTKGVLLLDHDGGFWLVHSVPNFPP 137
>AF045937-1|AAC35751.1| 360|Homo sapiens deoxyribonuclease II
precursor protein.
Length = 360
Score = 71.7 bits (168), Expect = 2e-12
Identities = 41/105 (39%), Positives = 55/105 (52%), Gaps = 2/105 (1%)
Frame = +3
Query: 39 LLKLFLFAFFINDSLCLTPQCRNEKGEPIDWFYVYKLPRERNHLNPLVRRGVAYMHLTPS 218
++ L L A + LT C + G+P+DWF VYKLP R +RG+ Y +L S
Sbjct: 1 MIPLLLAALLCVPAGALT--CYGDSGQPVDWFVVYKLPALRGS-GEAAQRGLQYKYLDES 57
Query: 219 KLRGGWIMSDLAISDPRSMVGRTLAPLYQD--KNIISLVYNDQPP 347
GGW I+ P VGR+L PLY+ + L+YNDQPP
Sbjct: 58 S--GGWRDGRALINSPEGAVGRSLQPLYRSNTSQLAFLLYNDQPP 100
Score = 43.6 bits (98), Expect = 7e-04
Identities = 18/26 (69%), Positives = 19/26 (73%)
Frame = +3
Query: 540 GHTKGVILGDKFTSLWLVHSVPRFPP 617
GHTKGV+L D WLVHSVP FPP
Sbjct: 112 GHTKGVLLLDHDGGFWLVHSVPNFPP 137
>AD000092-2|AAB51172.1| 348|Homo sapiens hypothetical human protein
R31240_2 protein.
Length = 348
Score = 71.7 bits (168), Expect = 2e-12
Identities = 41/105 (39%), Positives = 55/105 (52%), Gaps = 2/105 (1%)
Frame = +3
Query: 39 LLKLFLFAFFINDSLCLTPQCRNEKGEPIDWFYVYKLPRERNHLNPLVRRGVAYMHLTPS 218
++ L L A + LT C + G+P+DWF VYKLP R +RG+ Y +L S
Sbjct: 1 MIPLLLAALLCVPAGALT--CYGDSGQPVDWFVVYKLPALRGS-GEAAQRGLQYKYLDES 57
Query: 219 KLRGGWIMSDLAISDPRSMVGRTLAPLYQD--KNIISLVYNDQPP 347
GGW I+ P VGR+L PLY+ + L+YNDQPP
Sbjct: 58 S--GGWRDGRALINSPEGAVGRSLQPLYRSNTSQLAFLLYNDQPP 100
Score = 43.6 bits (98), Expect = 7e-04
Identities = 18/26 (69%), Positives = 19/26 (73%)
Frame = +3
Query: 540 GHTKGVILGDKFTSLWLVHSVPRFPP 617
GHTKGV+L D WLVHSVP FPP
Sbjct: 112 GHTKGVLLLDHDGGFWLVHSVPNFPP 137
>AB008564-1|BAB55598.1| 360|Homo sapiens deoxyribonuclease II
protein.
Length = 360
Score = 71.7 bits (168), Expect = 2e-12
Identities = 41/105 (39%), Positives = 55/105 (52%), Gaps = 2/105 (1%)
Frame = +3
Query: 39 LLKLFLFAFFINDSLCLTPQCRNEKGEPIDWFYVYKLPRERNHLNPLVRRGVAYMHLTPS 218
++ L L A + LT C + G+P+DWF VYKLP R +RG+ Y +L S
Sbjct: 1 MIPLLLAALLCVPAGALT--CYGDSGQPVDWFVVYKLPALRGS-GEAAQRGLQYKYLDES 57
Query: 219 KLRGGWIMSDLAISDPRSMVGRTLAPLYQD--KNIISLVYNDQPP 347
GGW I+ P VGR+L PLY+ + L+YNDQPP
Sbjct: 58 S--GGWRDGRALINSPEGAVGRSLQPLYRSNTSQLAFLLYNDQPP 100
Score = 43.6 bits (98), Expect = 7e-04
Identities = 18/26 (69%), Positives = 19/26 (73%)
Frame = +3
Query: 540 GHTKGVILGDKFTSLWLVHSVPRFPP 617
GHTKGV+L D WLVHSVP FPP
Sbjct: 112 GHTKGVLLLDHDGGFWLVHSVPNFPP 137
>AB004574-1|BAA28623.1| 360|Homo sapiens deoxyribonuclease II
protein.
Length = 360
Score = 71.7 bits (168), Expect = 2e-12
Identities = 41/105 (39%), Positives = 55/105 (52%), Gaps = 2/105 (1%)
Frame = +3
Query: 39 LLKLFLFAFFINDSLCLTPQCRNEKGEPIDWFYVYKLPRERNHLNPLVRRGVAYMHLTPS 218
++ L L A + LT C + G+P+DWF VYKLP R +RG+ Y +L S
Sbjct: 1 MIPLLLAALLCVPAGALT--CYGDSGQPVDWFVVYKLPALRGS-GEAAQRGLQYKYLDES 57
Query: 219 KLRGGWIMSDLAISDPRSMVGRTLAPLYQD--KNIISLVYNDQPP 347
GGW I+ P VGR+L PLY+ + L+YNDQPP
Sbjct: 58 S--GGWRDGRALINSPEGAVGRSLQPLYRSNTSQLAFLLYNDQPP 100
Score = 43.6 bits (98), Expect = 7e-04
Identities = 18/26 (69%), Positives = 19/26 (73%)
Frame = +3
Query: 540 GHTKGVILGDKFTSLWLVHSVPRFPP 617
GHTKGV+L D WLVHSVP FPP
Sbjct: 112 GHTKGVLLLDHDGGFWLVHSVPNFPP 137
>AL359273-6|CAH73126.1| 361|Homo sapiens deoxyribonuclease II beta
protein.
Length = 361
Score = 63.7 bits (148), Expect = 6e-10
Identities = 40/119 (33%), Positives = 66/119 (55%), Gaps = 5/119 (4%)
Frame = +3
Query: 6 ERLDSKTLVMSLLKLFLFAFFINDSLCLTPQCRNEKGEPIDWFYVYKLPRERNHLNPLVR 185
+++ ++ L S LFL F + + ++ CRNE+G+ +DWF YKLP+ +N +
Sbjct: 3 QKMMARLLRTSFALLFLGLFGVLGAATIS--CRNEEGKAVDWFTFYKLPKRQNKESG--E 58
Query: 186 RGVAYMHLTPSKLRGGWIMSDLAISDPRSMVGRTLAPLYQ-----DKNIISLVYNDQPP 347
G+ Y++L S R W S+ ++D +S++GRTL LY+ N L+YND P
Sbjct: 59 TGLEYLYL-DSTTR-SWRKSEQLMNDTKSVLGRTLQQLYEAYASKSNNTAYLIYNDGVP 115
Score = 56.4 bits (130), Expect = 9e-08
Identities = 23/45 (51%), Positives = 31/45 (68%)
Frame = +3
Query: 540 GHTKGVILGDKFTSLWLVHSVPRFPPIPDLIHGLNVSGYDYPTTG 674
GHTKG++L ++ WL+HS+P+FPPIP+ GYDYP TG
Sbjct: 125 GHTKGLLLWNRVQGFWLIHSIPQFPPIPE-------EGYDYPPTG 162
>AF334602-1|AAL34449.1| 361|Homo sapiens endonuclease DLAD protein.
Length = 361
Score = 63.7 bits (148), Expect = 6e-10
Identities = 40/119 (33%), Positives = 66/119 (55%), Gaps = 5/119 (4%)
Frame = +3
Query: 6 ERLDSKTLVMSLLKLFLFAFFINDSLCLTPQCRNEKGEPIDWFYVYKLPRERNHLNPLVR 185
+++ ++ L S LFL F + + ++ CRNE+G+ +DWF YKLP+ +N +
Sbjct: 3 QKMMARLLRTSFALLFLGLFGVLGAATIS--CRNEEGKAVDWFTFYKLPKRQNKESG--E 58
Query: 186 RGVAYMHLTPSKLRGGWIMSDLAISDPRSMVGRTLAPLYQ-----DKNIISLVYNDQPP 347
G+ Y++L S R W S+ ++D +S++GRTL LY+ N L+YND P
Sbjct: 59 TGLEYLYL-DSTTR-SWRKSEQLMNDTKSVLGRTLQQLYEAYASKSNNTAYLIYNDGVP 115
Score = 56.4 bits (130), Expect = 9e-08
Identities = 23/45 (51%), Positives = 31/45 (68%)
Frame = +3
Query: 540 GHTKGVILGDKFTSLWLVHSVPRFPPIPDLIHGLNVSGYDYPTTG 674
GHTKG++L ++ WL+HS+P+FPPIP+ GYDYP TG
Sbjct: 125 GHTKGLLLWNRVQGFWLIHSIPQFPPIPE-------EGYDYPPTG 162
>BC126138-1|AAI26139.2| 357|Homo sapiens deoxyribonuclease II beta
protein.
Length = 357
Score = 62.9 bits (146), Expect = 1e-09
Identities = 40/115 (34%), Positives = 64/115 (55%), Gaps = 5/115 (4%)
Frame = +3
Query: 18 SKTLVMSLLKLFLFAFFINDSLCLTPQCRNEKGEPIDWFYVYKLPRERNHLNPLVRRGVA 197
++ L S LFL F + + ++ CRNE+G+ +DWF YKLP+++N + G+
Sbjct: 3 ARLLRTSFALLFLGLFGVLGAATIS--CRNEEGKAVDWFTFYKLPKKQNKESG--ETGLE 58
Query: 198 YMHLTPSKLRGGWIMSDLAISDPRSMVGRTLAPLYQ-----DKNIISLVYNDQPP 347
Y++L S R W S+ ++D +S++GRTL LY+ N L+YND P
Sbjct: 59 YLYL-DSTTR-SWRKSEQLMNDTKSVLGRTLQQLYEAYASKSNNTAYLIYNDGVP 111
Score = 56.4 bits (130), Expect = 9e-08
Identities = 23/45 (51%), Positives = 31/45 (68%)
Frame = +3
Query: 540 GHTKGVILGDKFTSLWLVHSVPRFPPIPDLIHGLNVSGYDYPTTG 674
GHTKG++L ++ WL+HS+P+FPPIP+ GYDYP TG
Sbjct: 121 GHTKGLLLWNRVQGFWLIHSIPQFPPIPE-------EGYDYPPTG 158
>BC126136-1|AAI26137.2| 357|Homo sapiens deoxyribonuclease II beta
protein.
Length = 357
Score = 62.9 bits (146), Expect = 1e-09
Identities = 40/115 (34%), Positives = 64/115 (55%), Gaps = 5/115 (4%)
Frame = +3
Query: 18 SKTLVMSLLKLFLFAFFINDSLCLTPQCRNEKGEPIDWFYVYKLPRERNHLNPLVRRGVA 197
++ L S LFL F + + ++ CRNE+G+ +DWF YKLP+++N + G+
Sbjct: 3 ARLLRTSFALLFLGLFGVLGAATIS--CRNEEGKAVDWFTFYKLPKKQNKESG--ETGLE 58
Query: 198 YMHLTPSKLRGGWIMSDLAISDPRSMVGRTLAPLYQ-----DKNIISLVYNDQPP 347
Y++L S R W S+ ++D +S++GRTL LY+ N L+YND P
Sbjct: 59 YLYL-DSTTR-SWRKSEQLMNDTKSVLGRTLQQLYEAYASKSNNTAYLIYNDGVP 111
Score = 56.4 bits (130), Expect = 9e-08
Identities = 23/45 (51%), Positives = 31/45 (68%)
Frame = +3
Query: 540 GHTKGVILGDKFTSLWLVHSVPRFPPIPDLIHGLNVSGYDYPTTG 674
GHTKG++L ++ WL+HS+P+FPPIP+ GYDYP TG
Sbjct: 121 GHTKGLLLWNRVQGFWLIHSIPQFPPIPE-------EGYDYPPTG 158
>AF274571-1|AAF76893.1| 357|Homo sapiens deoxyribonuclease II beta
protein.
Length = 357
Score = 62.5 bits (145), Expect = 1e-09
Identities = 40/115 (34%), Positives = 63/115 (54%), Gaps = 5/115 (4%)
Frame = +3
Query: 18 SKTLVMSLLKLFLFAFFINDSLCLTPQCRNEKGEPIDWFYVYKLPRERNHLNPLVRRGVA 197
++ L S LFL F + + ++ CRNE+G+ +DWF YKLP+ +N + G+
Sbjct: 3 ARLLRTSFALLFLGLFGVLGAATIS--CRNEEGKAVDWFTFYKLPKRQNKESG--ETGLE 58
Query: 198 YMHLTPSKLRGGWIMSDLAISDPRSMVGRTLAPLYQ-----DKNIISLVYNDQPP 347
Y++L S R W S+ ++D +S++GRTL LY+ N L+YND P
Sbjct: 59 YLYL-DSTTR-SWRKSEQLMNDTKSVLGRTLQQLYEAYASKSNNTAYLIYNDGVP 111
Score = 56.4 bits (130), Expect = 9e-08
Identities = 23/45 (51%), Positives = 31/45 (68%)
Frame = +3
Query: 540 GHTKGVILGDKFTSLWLVHSVPRFPPIPDLIHGLNVSGYDYPTTG 674
GHTKG++L ++ WL+HS+P+FPPIP+ GYDYP TG
Sbjct: 121 GHTKGLLLWNRVQGFWLIHSIPQFPPIPE-------EGYDYPPTG 158
>BC080621-1|AAH80621.1| 251|Homo sapiens DNASE2B protein protein.
Length = 251
Score = 56.4 bits (130), Expect = 9e-08
Identities = 23/45 (51%), Positives = 31/45 (68%)
Frame = +3
Query: 540 GHTKGVILGDKFTSLWLVHSVPRFPPIPDLIHGLNVSGYDYPTTG 674
GHTKG++L ++ WL+HS+P+FPPIP+ GYDYP TG
Sbjct: 15 GHTKGLLLWNRVQGFWLIHSIPQFPPIPE-------EGYDYPPTG 52
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 95,075,765
Number of Sequences: 237096
Number of extensions: 1964819
Number of successful extensions: 3411
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 3261
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3382
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 7671262118
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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