Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmte22f04
(621 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q4RFE2 Cluster: Chromosome 8 SCAF15119, whole genome sh... 128 1e-28
UniRef50_Q28BZ2 Cluster: Histidine triad nucleotide binding prot... 118 9e-26
UniRef50_UPI0000D55AC3 Cluster: PREDICTED: similar to histidine ... 116 5e-25
UniRef50_Q16YN6 Cluster: Protein kinase C inhibitor, putative; n... 112 6e-24
UniRef50_UPI00015B4104 Cluster: PREDICTED: hypothetical protein;... 110 2e-23
UniRef50_Q9NQE9 Cluster: Histidine triad nucleotide binding prot... 109 5e-23
UniRef50_A7SFV5 Cluster: Predicted protein; n=1; Nematostella ve... 109 7e-23
UniRef50_UPI0000E47ACB Cluster: PREDICTED: hypothetical protein,... 107 2e-22
UniRef50_Q6IIA4 Cluster: HDC19222; n=1; Drosophila melanogaster|... 98 1e-19
UniRef50_UPI0000DB7407 Cluster: PREDICTED: similar to histidine ... 97 3e-19
UniRef50_Q4RR26 Cluster: Chromosome 14 SCAF15003, whole genome s... 93 4e-18
UniRef50_Q9VQ59 Cluster: CG15362-PA; n=3; Sophophora|Rep: CG1536... 88 2e-16
UniRef50_Q0V966 Cluster: Zgc:136256; n=4; Danio rerio|Rep: Zgc:1... 82 1e-14
UniRef50_Q01IH1 Cluster: OSIGBa0159I10.14 protein; n=6; Magnolio... 79 6e-14
UniRef50_Q84VV6 Cluster: At4g16566; n=2; Arabidopsis thaliana|Re... 76 8e-13
UniRef50_Q18227 Cluster: Putative uncharacterized protein; n=2; ... 73 7e-12
UniRef50_Q4PA08 Cluster: Putative uncharacterized protein; n=1; ... 70 5e-11
UniRef50_UPI00006CEB92 Cluster: HIT domain containing protein; n... 69 9e-11
UniRef50_Q54DF5 Cluster: Putative uncharacterized protein; n=1; ... 68 2e-10
UniRef50_UPI0000D55BA8 Cluster: PREDICTED: similar to aprataxin;... 60 3e-08
UniRef50_Q55V28 Cluster: Putative uncharacterized protein; n=1; ... 59 7e-08
UniRef50_Q5TVU2 Cluster: ENSANGP00000027488; n=1; Anopheles gamb... 59 1e-07
UniRef50_UPI00006CC86C Cluster: HIT domain containing protein; n... 58 1e-07
UniRef50_Q83DE2 Cluster: HIT family protein; n=24; Bacteria|Rep:... 53 5e-06
UniRef50_Q7PTZ0 Cluster: ENSANGP00000012901; n=2; Anopheles gamb... 53 6e-06
UniRef50_UPI00015B4880 Cluster: PREDICTED: similar to FHA-HIT; n... 51 3e-05
UniRef50_P61802 Cluster: Aprataxin; n=1; Ciona intestinalis|Rep:... 51 3e-05
UniRef50_P61799 Cluster: Aprataxin; n=21; Deuterostomia|Rep: Apr... 49 1e-04
UniRef50_O66536 Cluster: Uncharacterized HIT-like protein aq_141... 48 2e-04
UniRef50_Q1CY35 Cluster: HIT domain protein; n=3; Bacteria|Rep: ... 47 3e-04
UniRef50_Q16F08 Cluster: Putative uncharacterized protein; n=2; ... 47 3e-04
UniRef50_A6VZM3 Cluster: Histidine triad (HIT) protein; n=4; Pro... 46 6e-04
UniRef50_A1G4L9 Cluster: Histidine triad (HIT) protein; n=3; Bac... 46 6e-04
UniRef50_A5K5T5 Cluster: Protein kinase C inhibitor, putative; n... 46 6e-04
UniRef50_A0W3X6 Cluster: Histidine triad (HIT) protein; n=3; Bac... 46 7e-04
UniRef50_Q2F5W9 Cluster: Protein kinase C inhibitor; n=3; Endopt... 46 7e-04
UniRef50_UPI000155CE00 Cluster: PREDICTED: similar to aprataxin;... 46 0.001
UniRef50_Q8KGB0 Cluster: HIT family protein; n=10; Bacteria|Rep:... 46 0.001
UniRef50_Q5R0G3 Cluster: HIT family hydrolase; n=20; Proteobacte... 45 0.001
UniRef50_Q7K6B1 Cluster: Protein kinase c inhibitor-like protein... 45 0.001
UniRef50_A5GQU3 Cluster: HIT family hydrolase; n=10; Bacteria|Re... 45 0.002
UniRef50_Q7Z2E3 Cluster: Aprataxin; n=44; Euteleostomi|Rep: Apra... 45 0.002
UniRef50_Q892R5 Cluster: Hit family protein; n=16; Bacteria|Rep:... 44 0.002
UniRef50_A4F9S9 Cluster: Protein kinase C inhibitor; n=3; Actino... 44 0.002
UniRef50_Q9BX68 Cluster: Histidine triad nucleotide-binding prot... 44 0.003
UniRef50_Q7W2X6 Cluster: MttA/Hcf106 family protein; n=30; Burkh... 44 0.004
UniRef50_Q558W0 Cluster: Putative uncharacterized protein; n=3; ... 43 0.007
UniRef50_Q727L0 Cluster: HIT family protein; n=2; Deltaproteobac... 42 0.009
UniRef50_Q02WI9 Cluster: Diadenosine tetraphosphate (Ap4A) hydro... 42 0.012
UniRef50_A7AQA5 Cluster: HIT domain containing protein; n=1; Bab... 42 0.012
UniRef50_A0BUI5 Cluster: Chromosome undetermined scaffold_129, w... 42 0.012
UniRef50_P32084 Cluster: Uncharacterized HIT-like protein Synpcc... 42 0.012
UniRef50_Q5Z134 Cluster: Putative uncharacterized protein; n=1; ... 42 0.016
UniRef50_A7A616 Cluster: Putative uncharacterized protein; n=2; ... 42 0.016
UniRef50_Q5K261 Cluster: Putative uncharacterized protein pkci; ... 41 0.021
UniRef50_Q3J6P8 Cluster: Histidine triad (HIT) protein; n=5; Pro... 41 0.027
UniRef50_A7HMY4 Cluster: Histidine triad (HIT) protein; n=2; The... 41 0.027
UniRef50_Q1YR93 Cluster: Protein kinase C inhibitor; n=2; Gammap... 40 0.036
UniRef50_Q11066 Cluster: Uncharacterized HIT-like protein Rv1262... 40 0.036
UniRef50_P0ACE9 Cluster: HIT-like protein ycfF; n=109; Bacteria|... 40 0.036
UniRef50_A1SHY4 Cluster: Histidine triad (HIT) protein precursor... 40 0.048
UniRef50_P49773 Cluster: Histidine triad nucleotide-binding prot... 40 0.048
UniRef50_Q8DK69 Cluster: Histidine triad nucleotide-binding prot... 40 0.063
UniRef50_A6T373 Cluster: HIT family protein; n=20; Betaproteobac... 40 0.063
UniRef50_Q8MSG8 Cluster: Aprataxin-like protein; n=6; Sophophora... 40 0.063
UniRef50_UPI0000D555E3 Cluster: PREDICTED: similar to Hypothetic... 39 0.084
UniRef50_Q8F673 Cluster: HIT family hydrolase; n=6; cellular org... 39 0.084
UniRef50_Q4FMD8 Cluster: Diadenosine tetraphosphate (Ap4A) hydro... 39 0.084
UniRef50_Q182D4 Cluster: Histidine triad nucleotide-binding prot... 39 0.084
UniRef50_Q6MTB0 Cluster: Histidine triad protein; n=2; Mycoplasm... 39 0.11
UniRef50_Q6AEC2 Cluster: Putative uncharacterized protein; n=3; ... 39 0.11
UniRef50_A3DF72 Cluster: Histidine triad (HIT) protein; n=2; Clo... 39 0.11
UniRef50_UPI000050FB45 Cluster: COG0537: Diadenosine tetraphosph... 38 0.15
UniRef50_A7H3E9 Cluster: HIT family protein; n=11; Campylobacter... 38 0.15
UniRef50_A1VWA8 Cluster: Histidine triad (HIT) protein; n=5; cel... 38 0.15
UniRef50_Q4N9V7 Cluster: Protein kinase C interacting protein 1,... 38 0.15
UniRef50_Q9V017 Cluster: Histidine triad (HIT) protein; n=4; The... 38 0.15
UniRef50_Q8PVK5 Cluster: Hit-like protein; n=4; Methanosarcinace... 38 0.15
UniRef50_O07817 Cluster: Protein hitA; n=7; Betaproteobacteria|R... 38 0.15
UniRef50_UPI000038E073 Cluster: hypothetical protein Faci_030002... 38 0.19
UniRef50_A7H6R9 Cluster: Histidine triad (HIT) protein; n=14; Ba... 38 0.19
UniRef50_Q5TX49 Cluster: ENSANGP00000029056; n=1; Anopheles gamb... 38 0.19
UniRef50_A1AWF6 Cluster: Histidine triad (HIT) protein; n=1; Can... 38 0.26
UniRef50_P73481 Cluster: Uncharacterized HIT-like protein slr123... 38 0.26
UniRef50_A6WDH4 Cluster: Histidine triad (HIT) protein; n=2; Act... 37 0.34
UniRef50_A6FN65 Cluster: HIT family protein; n=1; Roseobacter sp... 37 0.34
UniRef50_Q5WBH5 Cluster: Histidine triad protein involved in cel... 37 0.45
UniRef50_P64382 Cluster: Uncharacterized HIT-like protein HP_040... 37 0.45
UniRef50_Q9PK09 Cluster: Uncharacterized HIT-like protein TC_066... 37 0.45
UniRef50_Q5KLA4 Cluster: Hydrolase, putative; n=2; Dikarya|Rep: ... 36 0.78
UniRef50_Q67LQ3 Cluster: HIT family protein; n=1; Symbiobacteriu... 35 1.4
UniRef50_Q2LVF0 Cluster: Hit family hydrolase; n=1; Syntrophus a... 35 1.4
UniRef50_A5KT99 Cluster: Histidine triad (HIT) protein; n=2; can... 35 1.4
UniRef50_Q8K9I9 Cluster: Uncharacterized HIT-like protein BUsg_3... 35 1.4
UniRef50_Q65J74 Cluster: Putative uncharacterized protein; n=1; ... 35 1.8
UniRef50_Q970Y2 Cluster: 141aa long hypothetical histidine triad... 35 1.8
UniRef50_A1RXN8 Cluster: Histidine triad (HIT) protein; n=1; The... 35 1.8
UniRef50_Q88TZ2 Cluster: Cell-cycle regulation histidine triad p... 34 2.4
UniRef50_A7BYS1 Cluster: HIT family protein; n=2; Proteobacteria... 34 2.4
UniRef50_A7BDL4 Cluster: Putative uncharacterized protein; n=1; ... 34 2.4
UniRef50_Q4DJ40 Cluster: Adenosine 5'-monophosphoramidase, putat... 34 2.4
UniRef50_Q58276 Cluster: Uncharacterized HIT-like protein MJ0866... 34 2.4
UniRef50_A0LCF6 Cluster: Histidine triad (HIT) protein; n=3; Bac... 34 3.1
UniRef50_Q10MW4 Cluster: Basic helix-loop-helix, putative, expre... 34 3.1
UniRef50_Q74MW7 Cluster: NEQ519; n=1; Nanoarchaeum equitans|Rep:... 34 3.1
UniRef50_O07513 Cluster: Protein hit; n=16; Bacillaceae|Rep: Pro... 34 3.1
UniRef50_Q9PQL9 Cluster: Probable HIT protein; n=1; Ureaplasma p... 33 4.2
UniRef50_Q6A7Y9 Cluster: Putative cell-cycle regulation histidin... 33 4.2
UniRef50_Q4K6N7 Cluster: HIT family protein; n=1; Pseudomonas fl... 33 4.2
UniRef50_Q023M8 Cluster: Histidine triad (HIT) protein; n=2; Bac... 33 4.2
UniRef50_Q5CSR7 Cluster: Histidine triad (HIT) family zinc bindi... 33 4.2
UniRef50_A2E0S0 Cluster: HIT domain containing protein; n=1; Tri... 33 4.2
UniRef50_Q0LZX4 Cluster: Histidine triad (HIT) protein precursor... 33 5.5
UniRef50_A7FTJ1 Cluster: HIT family protein; n=4; Clostridium bo... 33 5.5
UniRef50_A5UUJ2 Cluster: Putative uncharacterized protein precur... 33 5.5
UniRef50_A3EUM2 Cluster: Histidine triad protein; n=1; Leptospir... 33 5.5
UniRef50_Q8YU88 Cluster: All2466 protein; n=5; Cyanobacteria|Rep... 33 7.3
UniRef50_Q7M8Z0 Cluster: HIT-FAMILY PROTEIN; n=12; Epsilonproteo... 33 7.3
UniRef50_Q6NFF8 Cluster: HIT family protein; n=4; Corynebacteriu... 33 7.3
UniRef50_Q03D63 Cluster: Diadenosine tetraphosphate (Ap4A) hydro... 33 7.3
UniRef50_Q4P3W7 Cluster: Putative uncharacterized protein; n=1; ... 33 7.3
UniRef50_Q4LEG8 Cluster: Histidine triad protein; n=1; unculture... 33 7.3
UniRef50_P42856 Cluster: 14 kDa zinc-binding protein; n=11; Euka... 33 7.3
UniRef50_UPI0000E46DB2 Cluster: PREDICTED: similar to RE33408p; ... 32 9.6
UniRef50_Q74I95 Cluster: Hit protein; n=5; Lactobacillus|Rep: Hi... 32 9.6
UniRef50_Q2BQP2 Cluster: HIT domain protein; n=1; Neptuniibacter... 32 9.6
UniRef50_A0LM74 Cluster: Histidine triad (HIT) protein; n=1; Syn... 32 9.6
UniRef50_A7QKZ8 Cluster: Chromosome chr8 scaffold_115, whole gen... 32 9.6
UniRef50_A3HAI2 Cluster: Histidine triad (HIT) protein; n=2; The... 32 9.6
UniRef50_O76463 Cluster: Nitrilase and fragile histidine triad f... 32 9.6
>UniRef50_Q4RFE2 Cluster: Chromosome 8 SCAF15119, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 8
SCAF15119, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 166
Score = 128 bits (308), Expect = 1e-28
Identities = 51/111 (45%), Positives = 80/111 (72%), Gaps = 1/111 (0%)
Frame = +2
Query: 2 EVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLS-IEDA 178
E+ FRDI+P + H L +P +H+ + KSL+ L+ RM+ + +E+L KN+++ + DA
Sbjct: 49 EISCFRDIRPGAPHHYLVVPTKHVGNCKSLSKEHVPLVQRMVELGKEILQKNDVTDLSDA 108
Query: 179 RFGYHWPPFRSVKHLHLHTIAPESEMGFIGRVIFKKNSYWFVSPEYVASIL 331
RFG+HWPPF SV HLHLH +AP S+MGF+ R+I++ NSYWF++ + + +L
Sbjct: 109 RFGFHWPPFCSVTHLHLHVLAPASQMGFMSRLIYRLNSYWFITADQLIQLL 159
>UniRef50_Q28BZ2 Cluster: Histidine triad nucleotide binding protein
3; n=2; Tetrapoda|Rep: Histidine triad nucleotide
binding protein 3 - Xenopus tropicalis (Western clawed
frog) (Silurana tropicalis)
Length = 153
Score = 118 bits (285), Expect = 9e-26
Identities = 48/104 (46%), Positives = 74/104 (71%), Gaps = 1/104 (0%)
Frame = +2
Query: 5 VCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLS-IEDAR 181
VC F+DI+PA H L +PK+H+ K+LT +L+ MM + + L KNN++ +ED R
Sbjct: 42 VC-FKDIRPAVTHHYLVVPKKHVGTCKTLTKDHVQLIKTMMEVGKSTLQKNNVTDLEDIR 100
Query: 182 FGYHWPPFRSVKHLHLHTIAPESEMGFIGRVIFKKNSYWFVSPE 313
G+H+PPF S+ HLHLH +AP S++GF+ R+I++ NSYWF++ +
Sbjct: 101 LGFHYPPFCSISHLHLHVLAPASQLGFLSRMIYRVNSYWFITAD 144
>UniRef50_UPI0000D55AC3 Cluster: PREDICTED: similar to histidine
triad protein 4; n=1; Tribolium castaneum|Rep:
PREDICTED: similar to histidine triad protein 4 -
Tribolium castaneum
Length = 138
Score = 116 bits (279), Expect = 5e-25
Identities = 48/106 (45%), Positives = 73/106 (68%)
Frame = +2
Query: 2 EVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDAR 181
++ +F+DIKPAS+ H L +PK HI +V SL+ L+N +++ S+++L+ +++D R
Sbjct: 24 KMIIFKDIKPASKHHFLAVPKEHIPNVNSLSKNQIPLINDLIAKSKQVLADKGGNLDDTR 83
Query: 182 FGYHWPPFRSVKHLHLHTIAPESEMGFIGRVIFKKNSYWFVSPEYV 319
G+H PPF SV HLHLH I+P SEM FI +FK NS+WF S + +
Sbjct: 84 LGFHLPPFNSVSHLHLHIISPVSEMSFISSFVFKPNSWWFTSVDQI 129
>UniRef50_Q16YN6 Cluster: Protein kinase C inhibitor, putative; n=2;
Culicidae|Rep: Protein kinase C inhibitor, putative -
Aedes aegypti (Yellowfever mosquito)
Length = 154
Score = 112 bits (270), Expect = 6e-24
Identities = 45/106 (42%), Positives = 72/106 (67%), Gaps = 1/106 (0%)
Frame = +2
Query: 5 VCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRM-MSISRELLSKNNLSIEDAR 181
+C+F+DI+PA+ H+L +PK H++DV+SLT A++ LL+ M + L + + + +
Sbjct: 34 ICIFKDIRPAAEHHLLAVPKYHLDDVRSLTEAERPLLDEMRQELGNVLKDQFQVDLAEVL 93
Query: 182 FGYHWPPFRSVKHLHLHTIAPESEMGFIGRVIFKKNSYWFVSPEYV 319
FG+H PPF +VKHLH+H + P MGFI R+IF+ NS WF + + +
Sbjct: 94 FGFHVPPFTTVKHLHMHGMGPVGSMGFISRMIFRPNSMWFKTDQTI 139
>UniRef50_UPI00015B4104 Cluster: PREDICTED: hypothetical protein;
n=1; Nasonia vitripennis|Rep: PREDICTED: hypothetical
protein - Nasonia vitripennis
Length = 144
Score = 110 bits (265), Expect = 2e-23
Identities = 50/107 (46%), Positives = 67/107 (62%)
Frame = +2
Query: 5 VCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDARF 184
V +DI PAS H L IPK HI + K L +EL ++M++ ++ K L R
Sbjct: 32 VACIKDINPASDHHYLIIPKNHIVNAKVLNKEHEELYDKMVATVDTIVDKLGLVKNSTRT 91
Query: 185 GYHWPPFRSVKHLHLHTIAPESEMGFIGRVIFKKNSYWFVSPEYVAS 325
G+HWPPF +V HLHLH I+P +MGFI ++FK NS+WFVS +YV S
Sbjct: 92 GFHWPPFTTVGHLHLHVISPVEKMGFIKNMMFKPNSHWFVSTDYVKS 138
>UniRef50_Q9NQE9 Cluster: Histidine triad nucleotide binding protein
3; n=22; Euteleostomi|Rep: Histidine triad nucleotide
binding protein 3 - Homo sapiens (Human)
Length = 182
Score = 109 bits (262), Expect = 5e-23
Identities = 41/106 (38%), Positives = 74/106 (69%), Gaps = 1/106 (0%)
Frame = +2
Query: 5 VCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLS-IEDAR 181
+C F+DIKPA+ H L +PK+HI + ++L EL+ M+++ + +L +NN + + R
Sbjct: 72 IC-FKDIKPAATHHYLVVPKKHIGNCRTLRKDQVELVENMVTVGKTILERNNFTDFTNVR 130
Query: 182 FGYHWPPFRSVKHLHLHTIAPESEMGFIGRVIFKKNSYWFVSPEYV 319
G+H PPF S+ HLHLH +AP ++GF+ +++++ NSYWF++ +++
Sbjct: 131 MGFHMPPFCSISHLHLHVLAPVDQLGFLSKLVYRVNSYWFITADHL 176
>UniRef50_A7SFV5 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 163
Score = 109 bits (261), Expect = 7e-23
Identities = 43/106 (40%), Positives = 70/106 (66%)
Frame = +2
Query: 2 EVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDAR 181
E F+D++PA+ H L IPK+H + KSLT D L+ ++M + +++L + N + ED
Sbjct: 31 ETLTFKDLRPATDHHYLVIPKQHYGNPKSLTGDDLPLVEKLMDVGKKVLVQQNANTEDTV 90
Query: 182 FGYHWPPFRSVKHLHLHTIAPESEMGFIGRVIFKKNSYWFVSPEYV 319
G+HWPPF S++HLHLH I+ S+M F R I++ S+WF + +++
Sbjct: 91 IGFHWPPFNSIQHLHLHVISDASQMRFASRHIYRPGSWWFATVDWM 136
>UniRef50_UPI0000E47ACB Cluster: PREDICTED: hypothetical protein,
partial; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: hypothetical protein, partial -
Strongylocentrotus purpuratus
Length = 104
Score = 107 bits (258), Expect = 2e-22
Identities = 43/100 (43%), Positives = 65/100 (65%)
Frame = +2
Query: 8 CVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDARFG 187
CVF DI+P+++ H+L IPK H +VKSL L+ + + +L +I DAR G
Sbjct: 5 CVFHDIRPSTKEHLLIIPKSHHGNVKSLDKCQIPLVQYLYQVGEAVLEARGGNIADARVG 64
Query: 188 YHWPPFRSVKHLHLHTIAPESEMGFIGRVIFKKNSYWFVS 307
+HWPPF ++ HLHLH + P SEM +G+++ + NS+WFV+
Sbjct: 65 FHWPPFNTIDHLHLHVVYPTSEMNLLGKIMNRPNSFWFVT 104
>UniRef50_Q6IIA4 Cluster: HDC19222; n=1; Drosophila
melanogaster|Rep: HDC19222 - Drosophila melanogaster
(Fruit fly)
Length = 139
Score = 98.3 bits (234), Expect = 1e-19
Identities = 41/97 (42%), Positives = 65/97 (67%)
Frame = +2
Query: 11 VFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDARFGY 190
+F+DIKPAS+ H L + K+H +K L + L+ M + ++LL +S++DA FG+
Sbjct: 30 IFQDIKPASQHHYLAVTKKHYASLKDLNKSHDSLVQLMENALKDLLVSKGVSVDDALFGF 89
Query: 191 HWPPFRSVKHLHLHTIAPESEMGFIGRVIFKKNSYWF 301
H PPF +VKHLH+H I+P ++M F+ ++IF+ S WF
Sbjct: 90 HLPPFITVKHLHMHAISPRTQMTFLSKMIFRP-SVWF 125
>UniRef50_UPI0000DB7407 Cluster: PREDICTED: similar to histidine
triad protein 4; n=2; Apis mellifera|Rep: PREDICTED:
similar to histidine triad protein 4 - Apis mellifera
Length = 140
Score = 97.1 bits (231), Expect = 3e-19
Identities = 45/109 (41%), Positives = 61/109 (55%)
Frame = +2
Query: 5 VCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDARF 184
V +DI P S H L +PK HI + K L EL ++M++ + K L R
Sbjct: 28 VTCIKDIHPVSTHHYLILPKEHIRNAKQLKPEHSELYDKMLAAIDIISQKQGLDRAVTRT 87
Query: 185 GYHWPPFRSVKHLHLHTIAPESEMGFIGRVIFKKNSYWFVSPEYVASIL 331
G+HWPPF +V HLHLH I+P S + F R +++ S WFVS +YV S L
Sbjct: 88 GFHWPPFNTVSHLHLHVISPISNIKFYKRYMYEPGSCWFVSTDYVKSRL 136
>UniRef50_Q4RR26 Cluster: Chromosome 14 SCAF15003, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 14
SCAF15003, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 277
Score = 93.5 bits (222), Expect = 4e-18
Identities = 39/103 (37%), Positives = 65/103 (63%), Gaps = 1/103 (0%)
Frame = +2
Query: 2 EVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNL-SIEDA 178
E+ FRD+KP + H L + +RHI++ + L + L+ RM+ ++R +L +N + + ED
Sbjct: 175 ELLCFRDVKPGAETHFLVVTRRHIDNCRMLQTQHIPLVERMVEVARSVLEENKVHNSEDN 234
Query: 179 RFGYHWPPFRSVKHLHLHTIAPESEMGFIGRVIFKKNSYWFVS 307
R G+H PPF SV HLHLH + P S+M ++ + S+WF++
Sbjct: 235 RMGFHLPPFTSVPHLHLHVLCPASKMNVRAQLRYGPQSHWFIT 277
Score = 73.3 bits (172), Expect = 4e-12
Identities = 36/85 (42%), Positives = 50/85 (58%), Gaps = 1/85 (1%)
Frame = +2
Query: 5 VCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLS-IEDAR 181
VC F+DI PA+ H L +P HI SL +L+ RM + R +L ++ + D R
Sbjct: 6 VC-FKDIYPAAPHHYLVVPVPHIISCHSLQRRHVKLVERMAEMGRAVLRDQGITDLSDIR 64
Query: 182 FGYHWPPFRSVKHLHLHTIAPESEM 256
G+H PPF SV HLHLH +AP S++
Sbjct: 65 LGFHQPPFTSVHHLHLHVLAPASQI 89
>UniRef50_Q9VQ59 Cluster: CG15362-PA; n=3; Sophophora|Rep:
CG15362-PA - Drosophila melanogaster (Fruit fly)
Length = 168
Score = 87.8 bits (208), Expect = 2e-16
Identities = 41/100 (41%), Positives = 59/100 (59%)
Frame = +2
Query: 2 EVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDAR 181
E +F+D PA+R H L IPK H + +K+L + L+ RM E L N+ ++A
Sbjct: 55 EYVIFKDKYPAARLHYLAIPKEHFDSLKALNKSHVGLVRRMEQGMMEFLRSQNVDPKEAI 114
Query: 182 FGYHWPPFRSVKHLHLHTIAPESEMGFIGRVIFKKNSYWF 301
G+H PPF SV+HLHLH I P ++M F ++ F S+WF
Sbjct: 115 VGFHLPPFISVRHLHLHGIFPPADMSFGNKISFMP-SFWF 153
>UniRef50_Q0V966 Cluster: Zgc:136256; n=4; Danio rerio|Rep:
Zgc:136256 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 160
Score = 81.8 bits (193), Expect = 1e-14
Identities = 43/111 (38%), Positives = 64/111 (57%), Gaps = 1/111 (0%)
Frame = +2
Query: 5 VCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLS-IEDAR 181
VC FRDI P + H L IPK+HI SL + D L+ M + R +L NN++ ++D
Sbjct: 46 VC-FRDINPGAPHHYLVIPKKHIYSCLSLYADDISLVRAMAEMGRNVLKANNVTDLKDIS 104
Query: 182 FGYHWPPFRSVKHLHLHTIAPESEMGFIGRVIFKKNSYWFVSPEYVASILM 334
G+H PP+ +V HLHL+ +AP S++ I K + W+++ E ILM
Sbjct: 105 LGFHVPPYITVPHLHLYVLAPYSQL--YKWAINKFRTNWYINEEKTVEILM 153
>UniRef50_Q01IH1 Cluster: OSIGBa0159I10.14 protein; n=6;
Magnoliophyta|Rep: OSIGBa0159I10.14 protein - Oryza
sativa (Rice)
Length = 141
Score = 79.4 bits (187), Expect = 6e-14
Identities = 36/81 (44%), Positives = 55/81 (67%), Gaps = 2/81 (2%)
Frame = +2
Query: 5 VCVFRDIKPASRFHILTIPKRHIEDVKSL--TSADKELLNRMMSISRELLSKNNLSIEDA 178
V F+DI P++ H L IP HI V +L T+ D +L++ M+++ R+LL+++ + E+
Sbjct: 28 VMAFKDINPSAFRHYLVIPIEHIPTVNNLQRTTEDHQLVSHMLAVGRDLLNRDAPNSEEQ 87
Query: 179 RFGYHWPPFRSVKHLHLHTIA 241
RFG+H PPF SV HLHLH +A
Sbjct: 88 RFGFHQPPFNSVDHLHLHCLA 108
>UniRef50_Q84VV6 Cluster: At4g16566; n=2; Arabidopsis thaliana|Rep:
At4g16566 - Arabidopsis thaliana (Mouse-ear cress)
Length = 146
Score = 75.8 bits (178), Expect = 8e-13
Identities = 40/83 (48%), Positives = 53/83 (63%), Gaps = 3/83 (3%)
Frame = +2
Query: 2 EVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKE--LLNRMMSISRELLSKNN-LSIE 172
+V F+DIKPA++ H L IPK HI V L D++ L+ M+S+ ++LL K+ SI
Sbjct: 28 KVIAFQDIKPAAQRHYLVIPKEHIPTVNDLQRRDEDYSLVRHMLSVGQQLLQKDAPQSIH 87
Query: 173 DARFGYHWPPFRSVKHLHLHTIA 241
RFG+H PPF SV HLHLH A
Sbjct: 88 --RFGFHQPPFNSVDHLHLHCFA 108
>UniRef50_Q18227 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 175
Score = 72.5 bits (170), Expect = 7e-12
Identities = 41/94 (43%), Positives = 52/94 (55%), Gaps = 7/94 (7%)
Frame = +2
Query: 11 VFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNL------SIE 172
V DIKP ++ H L + K+HI LT AD LL M RELL ++ ++E
Sbjct: 33 VINDIKPKAKNHYLVLSKQHIAKPTDLTVADVPLLEEMEKTGRELLREHLKKKGEADTVE 92
Query: 173 DA-RFGYHWPPFRSVKHLHLHTIAPESEMGFIGR 271
D R G+H PP SV HLH+H I P S+MG I R
Sbjct: 93 DMLRIGFHLPPLLSVHHLHMHIIYPISDMGLISR 126
>UniRef50_Q4PA08 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 196
Score = 69.7 bits (163), Expect = 5e-11
Identities = 35/81 (43%), Positives = 51/81 (62%), Gaps = 3/81 (3%)
Frame = +2
Query: 5 VCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISR---ELLSKNNLSIED 175
+C F D P + H+L IP+ HI +V+SLT EL+ +M ++ +L+S +N + E
Sbjct: 67 IC-FTDRSPGAAIHLLVIPRNHIANVQSLTHNHTELVRQMQALGNKALDLVSTSNCAPE- 124
Query: 176 ARFGYHWPPFRSVKHLHLHTI 238
RFG+H PP RSV HLHLH +
Sbjct: 125 RRFGFHIPPIRSVDHLHLHCL 145
>UniRef50_UPI00006CEB92 Cluster: HIT domain containing protein; n=1;
Tetrahymena thermophila SB210|Rep: HIT domain containing
protein - Tetrahymena thermophila SB210
Length = 142
Score = 68.9 bits (161), Expect = 9e-11
Identities = 36/94 (38%), Positives = 53/94 (56%), Gaps = 1/94 (1%)
Frame = +2
Query: 2 EVCVFRDIKPAS-RFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDA 178
E+ F DI AS + HIL PKRHI++V L D EL+ R+ + + L +++ + +
Sbjct: 29 EIFAFEDINIASSKRHILICPKRHIKNVNELNYLDIELVKRLEQVGIQTLQESHPN-QQY 87
Query: 179 RFGYHWPPFRSVKHLHLHTIAPESEMGFIGRVIF 280
RFGYH PP S+ HLHLH F ++I+
Sbjct: 88 RFGYHSPPLNSIDHLHLHGFVLPISNCFNNKIIY 121
>UniRef50_Q54DF5 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 166
Score = 67.7 bits (158), Expect = 2e-10
Identities = 37/97 (38%), Positives = 52/97 (53%)
Frame = +2
Query: 5 VCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDARF 184
V VF D P + H L P+ HI +K+LT D +L M ++ +L+++
Sbjct: 52 VIVFNDRTPKATVHYLICPREHIVSIKTLTQKDIPVLVEMKQVADQLIAEKFPGQSGIVL 111
Query: 185 GYHWPPFRSVKHLHLHTIAPESEMGFIGRVIFKKNSY 295
G+H PPF SVKHLHLH + P F + FKK+SY
Sbjct: 112 GFHSPPFYSVKHLHLHLLVPP----FTPK--FKKHSY 142
>UniRef50_UPI0000D55BA8 Cluster: PREDICTED: similar to aprataxin;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
aprataxin - Tribolium castaneum
Length = 199
Score = 60.5 bits (140), Expect = 3e-08
Identities = 29/79 (36%), Positives = 44/79 (55%)
Frame = +2
Query: 11 VFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDARFGY 190
+ RD P ++FH L +PK I +KS+TS LL M ++ EL+S++ + GY
Sbjct: 46 IIRDKYPKAKFHYLVLPKEDITSIKSVTSTHLSLLKHMEQVALELISRDKHKESTFKIGY 105
Query: 191 HWPPFRSVKHLHLHTIAPE 247
H P S+ LHLH I+ +
Sbjct: 106 HAEP--SMSRLHLHVISDD 122
>UniRef50_Q55V28 Cluster: Putative uncharacterized protein; n=1;
Filobasidiella neoformans|Rep: Putative uncharacterized
protein - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 127
Score = 59.3 bits (137), Expect = 7e-08
Identities = 39/118 (33%), Positives = 58/118 (49%), Gaps = 8/118 (6%)
Frame = +2
Query: 2 EVCVFRDIKPASRFHILTIPKRHI-EDVKSLTSADKELLNRMMSISRELLSKNNLSIEDA 178
E+ F D P + H+L IP+ H+ V+ LT LL+ M ++SR L+ S
Sbjct: 5 ELIAFHDRTPRAVTHLLIIPRSHVASSVRQLTHEHLPLLDSMAALSRTLVP----SKPTP 60
Query: 179 RFGYHWPPFRSVKHLHLHTIAPESEMGFIGRVIFKKNSY-------WFVSPEYVASIL 331
+ G+H PPF SV H+HLH + FIG+ + +Y WFV+ E + L
Sbjct: 61 KLGFHIPPFSSVPHIHLHVFS--GPHTFIGKFKYPVTTYAAGKGLGWFVTIEQARNTL 116
>UniRef50_Q5TVU2 Cluster: ENSANGP00000027488; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000027488 - Anopheles gambiae
str. PEST
Length = 121
Score = 58.8 bits (136), Expect = 1e-07
Identities = 26/77 (33%), Positives = 44/77 (57%)
Frame = +2
Query: 17 RDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDARFGYHW 196
RD+ P +R+H L +P+++I + LT D LL M +++ ++ + L + FGYH
Sbjct: 27 RDLYPKARYHFLVLPRKNINTLHELTIDDVALLKDMYGLAQSVIKEGGLDTKQFNFGYHL 86
Query: 197 PPFRSVKHLHLHTIAPE 247
P +K LHLH I+ +
Sbjct: 87 KP--HMKRLHLHVISKD 101
>UniRef50_UPI00006CC86C Cluster: HIT domain containing protein; n=1;
Tetrahymena thermophila SB210|Rep: HIT domain containing
protein - Tetrahymena thermophila SB210
Length = 181
Score = 58.4 bits (135), Expect = 1e-07
Identities = 27/69 (39%), Positives = 44/69 (63%)
Frame = +2
Query: 32 ASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDARFGYHWPPFRS 211
+S+ HIL P +HIE+ LTS D +LL+ + + ++L K++ ++ ++GYH PP S
Sbjct: 37 SSQRHILVCPIKHIENSSYLTSNDLQLLDEIHKVCEQILQKSHPG-KEYKYGYHIPPHVS 95
Query: 212 VKHLHLHTI 238
+ HLH H I
Sbjct: 96 IDHLHYHGI 104
>UniRef50_Q83DE2 Cluster: HIT family protein; n=24; Bacteria|Rep:
HIT family protein - Coxiella burnetii
Length = 113
Score = 53.2 bits (122), Expect = 5e-06
Identities = 26/81 (32%), Positives = 43/81 (53%), Gaps = 2/81 (2%)
Frame = +2
Query: 2 EVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDAR 181
+V F D P + HIL IP RHIE + +T D++LL M+ ++ L N++ + R
Sbjct: 23 QVVAFNDAAPQAPIHILVIPHRHIETINDVTPGDEDLLGHMVVVATRLAHDKNMAADGYR 82
Query: 182 --FGYHWPPFRSVKHLHLHTI 238
+ ++V H+HLH +
Sbjct: 83 LVMNCNRNGGQAVFHIHLHLL 103
>UniRef50_Q7PTZ0 Cluster: ENSANGP00000012901; n=2; Anopheles gambiae
str. PEST|Rep: ENSANGP00000012901 - Anopheles gambiae
str. PEST
Length = 130
Score = 52.8 bits (121), Expect = 6e-06
Identities = 26/79 (32%), Positives = 42/79 (53%)
Frame = +2
Query: 11 VFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDARFGY 190
V +D P + H L +P + I+ V L+S D LL M + + + L+++ FGY
Sbjct: 29 VIKDKYPKALHHFLVLPWKDIDSVYDLSSDDDGLLQNMYELGLKAIGTTGLTVDRFDFGY 88
Query: 191 HWPPFRSVKHLHLHTIAPE 247
H P S++ LHLH I+ +
Sbjct: 89 HMKP--SMRRLHLHVISKD 105
>UniRef50_UPI00015B4880 Cluster: PREDICTED: similar to FHA-HIT; n=1;
Nasonia vitripennis|Rep: PREDICTED: similar to FHA-HIT -
Nasonia vitripennis
Length = 205
Score = 50.8 bits (116), Expect = 3e-05
Identities = 36/111 (32%), Positives = 57/111 (51%), Gaps = 4/111 (3%)
Frame = +2
Query: 5 VCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDARF 184
+ V +D P +RFH L +PK+ I + +T D ELL M +I+ + + + +D F
Sbjct: 52 IAVIKDKYPKARFHYLVLPKKDISTISEVTRDDIELLQHMENIANKFVDIH----KDYEF 107
Query: 185 --GYHWPPFRSVKHLHLHTIAPESEMGFIGRVIFKKNSYW--FVSPEYVAS 325
GYH P S+ LHLH I+ + F R + K +W F +P ++ S
Sbjct: 108 LVGYHAIP--SMHRLHLHVISTD----FDSRCL-KTKQHWNSFTTPYFLPS 151
>UniRef50_P61802 Cluster: Aprataxin; n=1; Ciona intestinalis|Rep:
Aprataxin - Ciona intestinalis (Transparent sea squirt)
Length = 380
Score = 50.8 bits (116), Expect = 3e-05
Identities = 28/101 (27%), Positives = 53/101 (52%), Gaps = 2/101 (1%)
Frame = +2
Query: 2 EVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLS--KNNLSIED 175
++ V +D P +++H L +PK I K+L++ + ELL ++ + +EL + K+ +
Sbjct: 225 QIVVIKDKYPKAKYHWLILPKDSISSTKNLSTDNIELLKHILKVGQELAAEVKDKQPDVE 284
Query: 176 ARFGYHWPPFRSVKHLHLHTIAPESEMGFIGRVIFKKNSYW 298
RFGYH S+ +H+H I+ + + FK +W
Sbjct: 285 FRFGYH--AVASMSQMHMHVISQDFQSS-----SFKTKKHW 318
>UniRef50_P61799 Cluster: Aprataxin; n=21; Deuterostomia|Rep:
Aprataxin - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 324
Score = 48.8 bits (111), Expect = 1e-04
Identities = 27/82 (32%), Positives = 45/82 (54%), Gaps = 1/82 (1%)
Frame = +2
Query: 5 VCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSK-NNLSIEDAR 181
V V +D P +R+H L +P + I +K+L S ELL M ++ +++ + + R
Sbjct: 170 VVVIKDKYPKARYHWLVLPWQSISSLKALRSEHVELLKHMQRVADQMVEQCPDAHKLSFR 229
Query: 182 FGYHWPPFRSVKHLHLHTIAPE 247
GYH P S+ H+HLH I+ +
Sbjct: 230 LGYHAIP--SMSHVHLHVISQD 249
>UniRef50_O66536 Cluster: Uncharacterized HIT-like protein aq_141;
n=9; Bacteria|Rep: Uncharacterized HIT-like protein
aq_141 - Aquifex aeolicus
Length = 121
Score = 47.6 bits (108), Expect = 2e-04
Identities = 29/86 (33%), Positives = 45/86 (52%), Gaps = 7/86 (8%)
Frame = +2
Query: 2 EVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLS-IEDA 178
+V F DI P + HIL IPK+HI +++L D+ L+ M ++R++ ++ E+
Sbjct: 26 KVLAFHDINPVAPVHILIIPKKHIMGIQTLEPEDECLVGHMFYVARKIAEDLGIAPDENL 85
Query: 179 RFGYHW------PPFRSVKHLHLHTI 238
GY +SV HLHLH I
Sbjct: 86 NKGYRLVFNVGKDAGQSVFHLHLHLI 111
>UniRef50_Q1CY35 Cluster: HIT domain protein; n=3; Bacteria|Rep: HIT
domain protein - Myxococcus xanthus (strain DK 1622)
Length = 116
Score = 47.2 bits (107), Expect = 3e-04
Identities = 28/87 (32%), Positives = 46/87 (52%), Gaps = 7/87 (8%)
Frame = +2
Query: 2 EVCV-FRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDA 178
+VCV F DI P + H+L IP +HI V +T+ D+EL+ + + ++ + + D
Sbjct: 23 DVCVAFEDINPQAPTHVLFIPHKHIPTVNDITTEDRELVGHLFIAAAKVAQERGHA--DP 80
Query: 179 RFGY------HWPPFRSVKHLHLHTIA 241
GY H ++V H+HLH +A
Sbjct: 81 SDGYRVVMNTHAHAGQTVFHIHLHLLA 107
>UniRef50_Q16F08 Cluster: Putative uncharacterized protein; n=2;
Aedes aegypti|Rep: Putative uncharacterized protein -
Aedes aegypti (Yellowfever mosquito)
Length = 188
Score = 47.2 bits (107), Expect = 3e-04
Identities = 24/79 (30%), Positives = 40/79 (50%)
Frame = +2
Query: 11 VFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDARFGY 190
V RD P +R H L +P +I++V L LL M ++++ + N ++ G+
Sbjct: 30 VIRDKYPKARHHFLVLPWANIDNVYELIPVHIPLLKEMFQLAKQAIELNRCHQKEFAMGF 89
Query: 191 HWPPFRSVKHLHLHTIAPE 247
H P S+ LHLH I+ +
Sbjct: 90 HMRP--SMHRLHLHVISKD 106
>UniRef50_A6VZM3 Cluster: Histidine triad (HIT) protein; n=4;
Proteobacteria|Rep: Histidine triad (HIT) protein -
Marinomonas sp. MWYL1
Length = 113
Score = 46.4 bits (105), Expect = 6e-04
Identities = 22/81 (27%), Positives = 41/81 (50%), Gaps = 2/81 (2%)
Frame = +2
Query: 2 EVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDAR 181
+V F DI P + H L IPKRHI + LT D ++ ++ + + ++ + +S R
Sbjct: 23 DVIAFEDIMPKAPTHFLVIPKRHISTLNDLTDEDAPVVGKLQTTAAKIAKQKGISNAGYR 82
Query: 182 FGYHWPPF--RSVKHLHLHTI 238
+ ++V H+H+H +
Sbjct: 83 VVMNCNEMGGQTVYHIHMHVL 103
>UniRef50_A1G4L9 Cluster: Histidine triad (HIT) protein; n=3;
Bacteria|Rep: Histidine triad (HIT) protein -
Salinispora arenicola CNS205
Length = 113
Score = 46.4 bits (105), Expect = 6e-04
Identities = 21/77 (27%), Positives = 40/77 (51%)
Frame = +2
Query: 2 EVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDAR 181
+V F +P HI+ +PKRH+ + L A ++LL+R++ + R++ ++ R
Sbjct: 25 DVLAFEHTRPFWPVHIVVVPKRHVPSLVDLGDASRDLLHRVIEVVRQVAARVEREQGACR 84
Query: 182 FGYHWPPFRSVKHLHLH 232
+ ++ KHLH H
Sbjct: 85 VLTNLGRYQDSKHLHFH 101
>UniRef50_A5K5T5 Cluster: Protein kinase C inhibitor, putative; n=5;
cellular organisms|Rep: Protein kinase C inhibitor,
putative - Plasmodium vivax
Length = 185
Score = 46.4 bits (105), Expect = 6e-04
Identities = 33/85 (38%), Positives = 46/85 (54%), Gaps = 5/85 (5%)
Frame = +2
Query: 2 EVCVFRDIKPASRFHILTIPKRHIEDVKSLTSAD---KELLNRMMSISRELLSKNNLSIE 172
+V F DI P + HIL IPK + + L+ A+ KE+L MM E++ KNNL
Sbjct: 95 KVLAFNDINPQAPVHILVIPKMR-DGLTRLSKAEERHKEILGHMMWAVSEIVKKNNLG-- 151
Query: 173 DARFGYHWPP--FRSVKHLHLHTIA 241
D R + P +SV +LHLH +A
Sbjct: 152 DFRLVVNNGPEACQSVYYLHLHILA 176
>UniRef50_A0W3X6 Cluster: Histidine triad (HIT) protein; n=3;
Bacteria|Rep: Histidine triad (HIT) protein - Geobacter
lovleyi SZ
Length = 114
Score = 46.0 bits (104), Expect = 7e-04
Identities = 26/81 (32%), Positives = 39/81 (48%)
Frame = +2
Query: 5 VCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDARF 184
V F P H++ +PKRHIE + SL +D ELL +M ++ + + R
Sbjct: 29 VFAFYHTNPLWEHHVVLLPKRHIESLISLEESDNELLLELMRTAKLIAADFMARFGACRV 88
Query: 185 GYHWPPFRSVKHLHLHTIAPE 247
+ ++S KHLH H A E
Sbjct: 89 YTNLGTYQSSKHLHWHIGAGE 109
>UniRef50_Q2F5W9 Cluster: Protein kinase C inhibitor; n=3;
Endopterygota|Rep: Protein kinase C inhibitor - Bombyx
mori (Silk moth)
Length = 162
Score = 46.0 bits (104), Expect = 7e-04
Identities = 29/88 (32%), Positives = 45/88 (51%), Gaps = 1/88 (1%)
Frame = +2
Query: 2 EVCV-FRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDA 178
++C+ F DI P + H L IPKR I ++ + D ELL +M ++R L ++ S
Sbjct: 73 DLCLAFNDIAPQAPVHFLVIPKRRIARLQDAENNDNELLGHLMLVARSLGAQRAPSGWRL 132
Query: 179 RFGYHWPPFRSVKHLHLHTIAPESEMGF 262
+SV HLHLH + +MG+
Sbjct: 133 VVNNGKDGAQSVYHLHLHVLGGR-QMGW 159
>UniRef50_UPI000155CE00 Cluster: PREDICTED: similar to aprataxin;
n=1; Ornithorhynchus anatinus|Rep: PREDICTED: similar to
aprataxin - Ornithorhynchus anatinus
Length = 408
Score = 45.6 bits (103), Expect = 0.001
Identities = 26/84 (30%), Positives = 48/84 (57%), Gaps = 2/84 (2%)
Frame = +2
Query: 2 EVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDAR 181
+V V +D P +R H L +P I ++++T ELL M ++ ++L +++ + + +
Sbjct: 199 KVVVIKDKYPKARNHWLVLPWESIASLRAVTREHLELLKHMQAVGKKL-TQDCIDSDRLQ 257
Query: 182 F--GYHWPPFRSVKHLHLHTIAPE 247
F GYH P S+ H+HLH I+ +
Sbjct: 258 FRMGYHAIP--SMSHIHLHVISQD 279
>UniRef50_Q8KGB0 Cluster: HIT family protein; n=10; Bacteria|Rep:
HIT family protein - Chlorobium tepidum
Length = 128
Score = 45.6 bits (103), Expect = 0.001
Identities = 29/96 (30%), Positives = 44/96 (45%), Gaps = 5/96 (5%)
Frame = +2
Query: 5 VCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDAR- 181
V F DI P + H+L IP HI + L D E+ +++ +R + K + R
Sbjct: 29 VAAFHDINPVAPIHVLIIPLEHIRSLSDLKDGDSEIAAQILLAARIVAEKTGVLESGYRL 88
Query: 182 -FGYHWPPFRSVKHLHLHTIAPESEMG---FIGRVI 277
F +SV H+H H I ++ MG F GR +
Sbjct: 89 VFNNGEDALQSVGHIHAHLIGGKT-MGWPPFAGREV 123
>UniRef50_Q5R0G3 Cluster: HIT family hydrolase; n=20;
Proteobacteria|Rep: HIT family hydrolase - Idiomarina
loihiensis
Length = 122
Score = 45.2 bits (102), Expect = 0.001
Identities = 24/85 (28%), Positives = 47/85 (55%), Gaps = 2/85 (2%)
Frame = +2
Query: 14 FRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDARFGYH 193
F+DI P + FH L IPK+ I + + L+ + ++ +L +++N S + R +
Sbjct: 29 FKDINPQAPFHCLIIPKQPIATANDINEDNAGLVGHLYVVAAKLAAEHNFSQDGYRLVMN 88
Query: 194 WPPF--RSVKHLHLHTIAPESEMGF 262
+ ++V H+HLH +A + +MG+
Sbjct: 89 CNEYGGQTVYHIHLHMLAGK-QMGW 112
>UniRef50_Q7K6B1 Cluster: Protein kinase c inhibitor-like protein,
putative; n=3; Plasmodium|Rep: Protein kinase c
inhibitor-like protein, putative - Plasmodium falciparum
(isolate 3D7)
Length = 130
Score = 45.2 bits (102), Expect = 0.001
Identities = 31/85 (36%), Positives = 47/85 (55%), Gaps = 5/85 (5%)
Frame = +2
Query: 2 EVCVFRDIKPASRFHILTIPKRHIEDVKSLTSAD---KELLNRMMSISRELLSKNNLSIE 172
+V F DI P + HI+ IPKR + + L+ A+ KE+L +M E++ KNNL
Sbjct: 40 KVIAFNDIYPQAPVHIIVIPKRR-DGLTRLSKAEEKHKEILGHLMWAVAEIVRKNNLG-- 96
Query: 173 DARFGYHWPP--FRSVKHLHLHTIA 241
D R + P +S+ +LHLH +A
Sbjct: 97 DFRLVVNNGPEACQSIYYLHLHILA 121
>UniRef50_A5GQU3 Cluster: HIT family hydrolase; n=10; Bacteria|Rep:
HIT family hydrolase - Synechococcus sp. (strain RCC307)
Length = 234
Score = 44.8 bits (101), Expect = 0.002
Identities = 23/80 (28%), Positives = 41/80 (51%), Gaps = 1/80 (1%)
Frame = +2
Query: 2 EVCV-FRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDA 178
E C+ F DI+P + H+L IP++HI +K +D LL ++ ++ ++ + L
Sbjct: 145 EHCIAFADIQPQAPVHLLVIPRQHIPSLKEAQPSDSALLGHLLLVAAKVAKEAGLQDWRT 204
Query: 179 RFGYHWPPFRSVKHLHLHTI 238
++V HLH+H I
Sbjct: 205 VINTGAEAGQTVFHLHVHVI 224
>UniRef50_Q7Z2E3 Cluster: Aprataxin; n=44; Euteleostomi|Rep:
Aprataxin - Homo sapiens (Human)
Length = 356
Score = 44.8 bits (101), Expect = 0.002
Identities = 26/83 (31%), Positives = 43/83 (51%), Gaps = 1/83 (1%)
Frame = +2
Query: 2 EVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRE-LLSKNNLSIEDA 178
+V V +D P +R+H L +P I +K++ ELL M ++ + ++ S
Sbjct: 201 QVVVIKDKYPKARYHWLVLPWTSISSLKAVAREHLELLKHMHTVGEKVIVDFAGSSKLRF 260
Query: 179 RFGYHWPPFRSVKHLHLHTIAPE 247
R GYH P S+ H+HLH I+ +
Sbjct: 261 RLGYHAIP--SMSHVHLHVISQD 281
>UniRef50_Q892R5 Cluster: Hit family protein; n=16; Bacteria|Rep:
Hit family protein - Clostridium tetani
Length = 114
Score = 44.4 bits (100), Expect = 0.002
Identities = 20/80 (25%), Positives = 47/80 (58%), Gaps = 2/80 (2%)
Frame = +2
Query: 5 VCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDARF 184
+ F+DI P++ H+L IPK+HI+++ L+ D ++++ + +EL + +++ + R
Sbjct: 25 ILAFKDISPSAPTHVLVIPKKHIKNLNELSDNDAKIISHIYIKIKELAQQLDINEKGYRV 84
Query: 185 GYHW--PPFRSVKHLHLHTI 238
+ ++V+H+H H +
Sbjct: 85 VTNCGEQGGQTVEHIHFHLL 104
>UniRef50_A4F9S9 Cluster: Protein kinase C inhibitor; n=3;
Actinomycetales|Rep: Protein kinase C inhibitor -
Saccharopolyspora erythraea (strain NRRL 23338)
Length = 123
Score = 44.4 bits (100), Expect = 0.002
Identities = 23/90 (25%), Positives = 42/90 (46%), Gaps = 2/90 (2%)
Frame = +2
Query: 5 VCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDAR- 181
V RDI P + H+L +PK + L + D +LL ++ ++ E+ ++ R
Sbjct: 29 VIAIRDINPQAPTHVLVVPKTRYRNAAELAAKDPDLLAEVVRVAGEVAESEGIAESGYRL 88
Query: 182 -FGYHWPPFRSVKHLHLHTIAPESEMGFIG 268
F + +++ H+HLH + E G G
Sbjct: 89 LFNTNSDAGQTIFHVHLHLLGGERMGGLTG 118
>UniRef50_Q9BX68 Cluster: Histidine triad nucleotide-binding protein
2; n=61; cellular organisms|Rep: Histidine triad
nucleotide-binding protein 2 - Homo sapiens (Human)
Length = 163
Score = 44.0 bits (99), Expect = 0.003
Identities = 24/82 (29%), Positives = 40/82 (48%), Gaps = 6/82 (7%)
Frame = +2
Query: 11 VFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLS------IE 172
VFRD+ P + H L IPK+ I + D++LL ++ ++++ L I
Sbjct: 77 VFRDVAPQAPVHFLVIPKKPIPRISQAEEEDQQLLGHLLLVAKQTAKAEGLGDGYRLVIN 136
Query: 173 DARFGYHWPPFRSVKHLHLHTI 238
D + G +SV HLH+H +
Sbjct: 137 DGKLG-----AQSVYHLHIHVL 153
>UniRef50_Q7W2X6 Cluster: MttA/Hcf106 family protein; n=30;
Burkholderiales|Rep: MttA/Hcf106 family protein -
Bordetella parapertussis
Length = 122
Score = 43.6 bits (98), Expect = 0.004
Identities = 18/52 (34%), Positives = 29/52 (55%)
Frame = +2
Query: 2 EVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKN 157
E F DI PA+ H+L IP+RH+ ++ + D + L RM ++ L + N
Sbjct: 25 EFVAFHDINPAAPVHLLLIPRRHVVSLQDIAEGDADWLGRMTVLASRLAAGN 76
>UniRef50_Q558W0 Cluster: Putative uncharacterized protein; n=3;
Dictyostelium discoideum|Rep: Putative uncharacterized
protein - Dictyostelium discoideum AX4
Length = 390
Score = 42.7 bits (96), Expect = 0.007
Identities = 30/101 (29%), Positives = 50/101 (49%), Gaps = 8/101 (7%)
Frame = +2
Query: 20 DIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSIS----RELLSKNN----LSIED 175
D P ++ H L IP+ I + LT + +L M +++ E++SK+N L D
Sbjct: 256 DKYPKAKHHYLVIPRVEINTLDELTPSFIPMLEHMYNVADAIINEIISKDNDDDNLKKSD 315
Query: 176 ARFGYHWPPFRSVKHLHLHTIAPESEMGFIGRVIFKKNSYW 298
+ G+H P S+K LHLH I+ + ++ K N +W
Sbjct: 316 FKLGFHAIP--SMKRLHLHIISNDYNTKYL-----KNNKHW 349
>UniRef50_Q727L0 Cluster: HIT family protein; n=2;
Deltaproteobacteria|Rep: HIT family protein -
Desulfovibrio vulgaris (strain Hildenborough / ATCC
29579 / NCIMB8303)
Length = 142
Score = 42.3 bits (95), Expect = 0.009
Identities = 25/76 (32%), Positives = 39/76 (51%), Gaps = 2/76 (2%)
Frame = +2
Query: 17 RDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDARFGYHW 196
RD + H+L IPKRH ED SLT A+K + ++ R+ L+ + SI G +
Sbjct: 32 RDKYAVTEGHLLIIPKRHTEDYFSLTQAEKRDADALLRELRDELASADASISGFNVGVNC 91
Query: 197 --PPFRSVKHLHLHTI 238
+++ H H+H I
Sbjct: 92 GEDAGQTIFHAHIHLI 107
>UniRef50_Q02WI9 Cluster: Diadenosine tetraphosphate (Ap4A)
hydrolase related HIT family hydrolase; n=5;
Firmicutes|Rep: Diadenosine tetraphosphate (Ap4A)
hydrolase related HIT family hydrolase - Lactococcus
lactis subsp. cremoris (strain SK11)
Length = 122
Score = 41.9 bits (94), Expect = 0.012
Identities = 22/76 (28%), Positives = 37/76 (48%), Gaps = 1/76 (1%)
Frame = +2
Query: 14 FRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKN-NLSIEDARFGY 190
F D P S HIL PKRH+ LT ++E + ++ +S+ L +N + + +
Sbjct: 22 FYDAYPVSEGHILITPKRHVASYFELTKYEREAIEELLELSKSHLDENFHANAYNIGINV 81
Query: 191 HWPPFRSVKHLHLHTI 238
++V H H+H I
Sbjct: 82 GHAAGQTVFHCHVHLI 97
>UniRef50_A7AQA5 Cluster: HIT domain containing protein; n=1;
Babesia bovis|Rep: HIT domain containing protein -
Babesia bovis
Length = 180
Score = 41.9 bits (94), Expect = 0.012
Identities = 25/81 (30%), Positives = 37/81 (45%), Gaps = 2/81 (2%)
Frame = +2
Query: 5 VCVFRDIKPASRFHILTIPKRH--IEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDA 178
+ F DIKP + H L IPKRH + + + T A ++L MM E+ N+
Sbjct: 91 ILAFHDIKPVAPVHFLVIPKRHAGLTRLSNATDAHAKILGYMMVKVAEITRSLNIGDYRL 150
Query: 179 RFGYHWPPFRSVKHLHLHTIA 241
+ + HLH+H IA
Sbjct: 151 VINDGAGAGQQIFHLHMHVIA 171
>UniRef50_A0BUI5 Cluster: Chromosome undetermined scaffold_129,
whole genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_129,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 117
Score = 41.9 bits (94), Expect = 0.012
Identities = 26/88 (29%), Positives = 45/88 (51%), Gaps = 5/88 (5%)
Frame = +2
Query: 14 FRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMM----SISREL-LSKNNLSIEDA 178
F DI P ++ H+L IPK H++ + + + LL +M + ++L L + I D
Sbjct: 34 FEDINPKAKVHVLVIPKEHLDRLSNASEQHINLLGNLMYAVNRVGKQLQLEGYRVIINDG 93
Query: 179 RFGYHWPPFRSVKHLHLHTIAPESEMGF 262
+ G ++V HLH H ++ E+ GF
Sbjct: 94 QKG-----GQTVFHLHAHILSGENLTGF 116
>UniRef50_P32084 Cluster: Uncharacterized HIT-like protein
Synpcc7942_1390; n=22; cellular organisms|Rep:
Uncharacterized HIT-like protein Synpcc7942_1390 -
Synechococcus sp. (strain PCC 7942) (Anacystis nidulans
R2)
Length = 114
Score = 41.9 bits (94), Expect = 0.012
Identities = 25/86 (29%), Positives = 47/86 (54%), Gaps = 3/86 (3%)
Frame = +2
Query: 2 EVCV-FRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDA 178
++C+ FRD+ P + HIL IPK+ I ++ T+ + LL ++ + + ++ L+ E
Sbjct: 24 DLCLAFRDVAPQAPVHILVIPKQPIANLLEATAEHQALLGHLLLTVKAIAAQEGLT-EGY 82
Query: 179 RFGYHWPPF--RSVKHLHLHTIAPES 250
R + P ++V HLH+H + S
Sbjct: 83 RTVINTGPAGGQTVYHLHIHLLGGRS 108
>UniRef50_Q5Z134 Cluster: Putative uncharacterized protein; n=1;
Nocardia farcinica|Rep: Putative uncharacterized protein
- Nocardia farcinica
Length = 150
Score = 41.5 bits (93), Expect = 0.016
Identities = 27/83 (32%), Positives = 40/83 (48%), Gaps = 5/83 (6%)
Frame = +2
Query: 5 VCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISREL---LSKNNLSIED 175
+C F DI+P +R H L IPKRH L D EL M + + + + L+ +
Sbjct: 29 LCAFLDIRPIARGHTLVIPKRH---AAGLPDLDPELGAAMFRAAHRIALAMRRGGLAADG 85
Query: 176 ARFGYH--WPPFRSVKHLHLHTI 238
A + F++V H+HLH I
Sbjct: 86 ANLVLNDGRAAFQTVGHVHLHVI 108
>UniRef50_A7A616 Cluster: Putative uncharacterized protein; n=2;
Bifidobacterium adolescentis|Rep: Putative
uncharacterized protein - Bifidobacterium adolescentis
L2-32
Length = 124
Score = 41.5 bits (93), Expect = 0.016
Identities = 19/78 (24%), Positives = 37/78 (47%)
Frame = +2
Query: 14 FRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDARFGYH 193
F+DI P ++ H+L +P++H +V L D L M +++++ + F
Sbjct: 43 FKDINPKAKVHVLIVPRKHYANVAELAKEDPAQLAHMAEVAQKIADQEFHGAFRLIFNTG 102
Query: 194 WPPFRSVKHLHLHTIAPE 247
++V H+H H + E
Sbjct: 103 IDAGQTVFHVHAHVLTGE 120
>UniRef50_Q5K261 Cluster: Putative uncharacterized protein pkci;
n=3; cellular organisms|Rep: Putative uncharacterized
protein pkci - Guillardia theta (Cryptomonas phi)
Length = 181
Score = 41.1 bits (92), Expect = 0.021
Identities = 23/82 (28%), Positives = 42/82 (51%), Gaps = 2/82 (2%)
Frame = +2
Query: 2 EVCVFRDIKPASRFHILTIPKRH--IEDVKSLTSADKELLNRMMSISRELLSKNNLSIED 175
+V VF+DI P + H+L IPKR + ++ T+ + +L M+++ ++ S+ L
Sbjct: 91 KVLVFKDINPQAPTHLLVIPKRRETLSQLRFATAEHEGILGHMLAVVAKVASEEGLGDYR 150
Query: 176 ARFGYHWPPFRSVKHLHLHTIA 241
+ V HLH+H +A
Sbjct: 151 LVVNDGRGAGQEVFHLHMHVLA 172
>UniRef50_Q3J6P8 Cluster: Histidine triad (HIT) protein; n=5;
Proteobacteria|Rep: Histidine triad (HIT) protein -
Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848)
Length = 115
Score = 40.7 bits (91), Expect = 0.027
Identities = 24/93 (25%), Positives = 43/93 (46%), Gaps = 6/93 (6%)
Frame = +2
Query: 2 EVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLS----- 166
+V F DI P ++ H+L +P+ HI ++ L + L++ ++ + +L + L
Sbjct: 28 QVIAFEDIHPKAKIHLLLVPRSHISSLEQLEVKHEALISHLLLLLPDLARRQGLQDGFRT 87
Query: 167 -IEDARFGYHWPPFRSVKHLHLHTIAPESEMGF 262
I R G + V HLH+H + GF
Sbjct: 88 IINTGRGG-----GQEVDHLHIHLLGGSQLPGF 115
>UniRef50_A7HMY4 Cluster: Histidine triad (HIT) protein; n=2;
Thermotogaceae|Rep: Histidine triad (HIT) protein -
Fervidobacterium nodosum Rt17-B1
Length = 111
Score = 40.7 bits (91), Expect = 0.027
Identities = 21/86 (24%), Positives = 41/86 (47%)
Frame = +2
Query: 11 VFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDARFGY 190
V +DI+P + H+L I K+HI + L+ D + + ++ + +++ NL
Sbjct: 27 VIKDIRPVAPVHLLAIYKKHIATINDLSEEDSKNMWKLFEVIKKVTKDQNLESYRIVQNN 86
Query: 191 HWPPFRSVKHLHLHTIAPESEMGFIG 268
+ V H+H H I ++G +G
Sbjct: 87 GKDAGQEVHHIHFHIIGGR-KLGALG 111
>UniRef50_Q1YR93 Cluster: Protein kinase C inhibitor; n=2;
Gammaproteobacteria|Rep: Protein kinase C inhibitor -
gamma proteobacterium HTCC2207
Length = 120
Score = 40.3 bits (90), Expect = 0.036
Identities = 26/82 (31%), Positives = 41/82 (50%), Gaps = 2/82 (2%)
Frame = +2
Query: 11 VFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDARFGY 190
V DI P + H+L IP++ I + ADK LL +M ++ E+ + + E R
Sbjct: 30 VINDISPQAPIHMLVIPRQPIAKLADAIEADKALLGHLMWVAGEVARQAGVE-EAFRLVV 88
Query: 191 H--WPPFRSVKHLHLHTIAPES 250
+ ++V HLHLH +A S
Sbjct: 89 NNGRAAGQTVFHLHLHVLADPS 110
>UniRef50_Q11066 Cluster: Uncharacterized HIT-like protein
Rv1262c/MT1300; n=17; Mycobacterium|Rep: Uncharacterized
HIT-like protein Rv1262c/MT1300 - Mycobacterium
tuberculosis
Length = 144
Score = 40.3 bits (90), Expect = 0.036
Identities = 28/86 (32%), Positives = 43/86 (50%), Gaps = 9/86 (10%)
Frame = +2
Query: 20 DIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISR---------ELLSKNNLSIE 172
DI+P +R H L +PKRH D LT E L M++I + +L +++I
Sbjct: 29 DIRPFTRGHTLVLPKRHTVD---LTDTPPEALADMVAIGQRIARAARATKLADATHIAIN 85
Query: 173 DARFGYHWPPFRSVKHLHLHTIAPES 250
D R F++V H+HLH + P +
Sbjct: 86 DGR-----AAFQTVFHVHLHVLPPRN 106
>UniRef50_P0ACE9 Cluster: HIT-like protein ycfF; n=109;
Bacteria|Rep: HIT-like protein ycfF - Shigella flexneri
Length = 119
Score = 40.3 bits (90), Expect = 0.036
Identities = 21/80 (26%), Positives = 42/80 (52%), Gaps = 2/80 (2%)
Frame = +2
Query: 5 VCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDAR- 181
V FRDI P + HIL IP I V +++ ++ L RM++++ ++ + ++ + R
Sbjct: 26 VTAFRDISPQAPTHILIIPNILIPTVNDVSAEHEQALGRMITVAAKIAEQEGIAEDGYRL 85
Query: 182 -FGYHWPPFRSVKHLHLHTI 238
+ + V H+H+H +
Sbjct: 86 IMNTNRHGGQEVYHIHMHLL 105
>UniRef50_A1SHY4 Cluster: Histidine triad (HIT) protein precursor;
n=4; Actinobacteridae|Rep: Histidine triad (HIT) protein
precursor - Nocardioides sp. (strain BAA-499 / JS614)
Length = 112
Score = 39.9 bits (89), Expect = 0.048
Identities = 20/76 (26%), Positives = 36/76 (47%)
Frame = +2
Query: 14 FRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDARFGYH 193
FRDI P + H+L +P+ H + L +AD + +++ + + + + F
Sbjct: 28 FRDIDPKAPTHVLVVPRDHYTNAAELAAADPQATAELVTTAAAVAAAEGYADYRIVFNTG 87
Query: 194 WPPFRSVKHLHLHTIA 241
+SV H HLH +A
Sbjct: 88 AEAGQSVFHTHLHLLA 103
>UniRef50_P49773 Cluster: Histidine triad nucleotide-binding protein
1; n=46; cellular organisms|Rep: Histidine triad
nucleotide-binding protein 1 - Homo sapiens (Human)
Length = 126
Score = 39.9 bits (89), Expect = 0.048
Identities = 23/77 (29%), Positives = 38/77 (49%), Gaps = 2/77 (2%)
Frame = +2
Query: 14 FRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDARFGYH 193
F DI P + H L IPK+HI + D+ LL +M + ++ + L+ + R +
Sbjct: 41 FHDISPQAPTHFLVIPKKHISQISVAEDDDESLLGHLMIVGKKCAADLGLN-KGYRMVVN 99
Query: 194 --WPPFRSVKHLHLHTI 238
+SV H+HLH +
Sbjct: 100 EGSDGGQSVYHVHLHVL 116
>UniRef50_Q8DK69 Cluster: Histidine triad nucleotide-binding
protein; n=15; Bacteria|Rep: Histidine triad
nucleotide-binding protein - Synechococcus elongatus
(Thermosynechococcus elongatus)
Length = 114
Score = 39.5 bits (88), Expect = 0.063
Identities = 25/82 (30%), Positives = 41/82 (50%), Gaps = 3/82 (3%)
Frame = +2
Query: 2 EVCV-FRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDA 178
E+C+ FRDI P + HIL IPK+ I + D +L ++ ++ + L+
Sbjct: 24 ELCLAFRDINPQAPVHILVIPKKPIPQLSLAEPEDHRVLGHLLLTAKRIAEAEGLT-NGY 82
Query: 179 RFGYHWPP--FRSVKHLHLHTI 238
R + P ++V HLHLH +
Sbjct: 83 RVVINNGPDGGQTVYHLHLHLL 104
>UniRef50_A6T373 Cluster: HIT family protein; n=20;
Betaproteobacteria|Rep: HIT family protein -
Janthinobacterium sp. (strain Marseille) (Minibacterium
massiliensis)
Length = 128
Score = 39.5 bits (88), Expect = 0.063
Identities = 16/54 (29%), Positives = 30/54 (55%)
Frame = +2
Query: 2 EVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNL 163
++ F DI PA+ H L IPK+H+ + T+ D LL ++ ++ +L + +
Sbjct: 28 DLLAFNDINPAAPVHFLIIPKKHVATLADCTTEDAALLGKISLLAPKLAQEQGV 81
>UniRef50_Q8MSG8 Cluster: Aprataxin-like protein; n=6;
Sophophora|Rep: Aprataxin-like protein - Drosophila
melanogaster (Fruit fly)
Length = 662
Score = 39.5 bits (88), Expect = 0.063
Identities = 21/79 (26%), Positives = 38/79 (48%)
Frame = +2
Query: 11 VFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDARFGY 190
V D P ++ H L +P I + L + LL + ++R ++ + +D G+
Sbjct: 26 VIADKFPKAQHHYLVLPLADIPSIFHLNRSHLSLLEELHLLARNVVEVKGVRWQDFNVGF 85
Query: 191 HWPPFRSVKHLHLHTIAPE 247
H P S++ LHLH I+ +
Sbjct: 86 HAEP--SMQRLHLHVISKD 102
>UniRef50_UPI0000D555E3 Cluster: PREDICTED: similar to Hypothetical
HIT-like protein F21C3.3; n=3; Coelomata|Rep: PREDICTED:
similar to Hypothetical HIT-like protein F21C3.3 -
Tribolium castaneum
Length = 156
Score = 39.1 bits (87), Expect = 0.084
Identities = 26/80 (32%), Positives = 41/80 (51%), Gaps = 5/80 (6%)
Frame = +2
Query: 14 FRDIKPASRFHILTIPKRHIEDVKSLTSADK----ELLNRMMSISRELLSKN-NLSIEDA 178
F D+ P + H L IPK+ I + S+ +DK EL+ R +++E L L I +
Sbjct: 72 FNDVNPQAPVHFLVIPKQRIPMLDSVKDSDKDIMAELVLRAQKLAKERLPNGYRLVINNG 131
Query: 179 RFGYHWPPFRSVKHLHLHTI 238
+ G +SV HLH+H +
Sbjct: 132 KQG-----CQSVYHLHIHIL 146
>UniRef50_Q8F673 Cluster: HIT family hydrolase; n=6; cellular
organisms|Rep: HIT family hydrolase - Leptospira
interrogans
Length = 122
Score = 39.1 bits (87), Expect = 0.084
Identities = 22/82 (26%), Positives = 38/82 (46%), Gaps = 2/82 (2%)
Frame = +2
Query: 2 EVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDAR 181
E+ F DI P + HI+ IPK+HI + + + D LL ++ R+ + R
Sbjct: 32 EILAFYDISPQAPVHIVFIPKKHIPSLSEIENEDSHLLGNILLQIRDTAKNLGFAENGYR 91
Query: 182 FGYHWPP--FRSVKHLHLHTIA 241
+ ++V H+H H +A
Sbjct: 92 VVNNTGKNGGQTVFHIHFHLLA 113
>UniRef50_Q4FMD8 Cluster: Diadenosine tetraphosphate (Ap4A)
hydrolase and other HIT family hydrolases; n=3;
Bacteria|Rep: Diadenosine tetraphosphate (Ap4A)
hydrolase and other HIT family hydrolases - Pelagibacter
ubique
Length = 144
Score = 39.1 bits (87), Expect = 0.084
Identities = 27/99 (27%), Positives = 44/99 (44%), Gaps = 7/99 (7%)
Frame = +2
Query: 20 DIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDARFGYHWP 199
D P S FH L IPKRH+ D L + N ++ +E + + +++ G +
Sbjct: 42 DTYPVSEFHCLIIPKRHVVDYFDLNDDEVIACNNLIKQIKEEILLKDPAVKGFNIGTNAG 101
Query: 200 PF--RSVKHLHLHTIA-----PESEMGFIGRVIFKKNSY 295
+S+ H H+H I ++ G + VI KK Y
Sbjct: 102 VIAGQSILHCHIHLIPRREGDVDNPQGGVRSVIPKKQHY 140
>UniRef50_Q182D4 Cluster: Histidine triad nucleotide-binding
protein; n=7; Bacteria|Rep: Histidine triad
nucleotide-binding protein - Clostridium difficile
(strain 630)
Length = 116
Score = 39.1 bits (87), Expect = 0.084
Identities = 18/81 (22%), Positives = 38/81 (46%), Gaps = 2/81 (2%)
Frame = +2
Query: 5 VCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDARF 184
V F D+ P + +HIL +PK+H + + + + ++++ + + ++ + R
Sbjct: 24 VLAFNDLNPVAPYHILVVPKKHYDSLIDIPDKEMDIVSHIHVVINKIAKEKGFDQTGFRV 83
Query: 185 --GYHWPPFRSVKHLHLHTIA 241
+ VKHLH H +A
Sbjct: 84 INNCGSDGGQEVKHLHYHILA 104
>UniRef50_Q6MTB0 Cluster: Histidine triad protein; n=2;
Mycoplasma|Rep: Histidine triad protein - Mycoplasma
mycoides subsp. mycoides SC
Length = 132
Score = 38.7 bits (86), Expect = 0.11
Identities = 25/89 (28%), Positives = 43/89 (48%), Gaps = 5/89 (5%)
Frame = +2
Query: 14 FRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDARFGY- 190
F D++P S H+L IPK+H E + ++ D + L ++ + L++ + A F Y
Sbjct: 27 FLDVRPVSNGHLLIIPKKHFE---NFSACDDKYLQEVILAKKHLVNLLKEKLNPAGFNYL 83
Query: 191 ---HWPPFRSVKHLHLHTIAP-ESEMGFI 265
++V H H H + E E GF+
Sbjct: 84 SNEQAISGQTVLHYHEHIMPKYEKEKGFL 112
>UniRef50_Q6AEC2 Cluster: Putative uncharacterized protein; n=3;
Actinobacteria (class)|Rep: Putative uncharacterized
protein - Leifsonia xyli subsp. xyli
Length = 132
Score = 38.7 bits (86), Expect = 0.11
Identities = 22/77 (28%), Positives = 39/77 (50%), Gaps = 1/77 (1%)
Frame = +2
Query: 14 FRDIKPASRFHILTIPKR-HIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDARFGY 190
F+DI P + H+L +PK DV L + D ELL +++ +R L +++ F
Sbjct: 42 FKDIAPQAPVHLLVVPKTDQYRDVVELAAGDPELLAELVATARSLAAEHADGDFRLIFNT 101
Query: 191 HWPPFRSVKHLHLHTIA 241
++V H+H H ++
Sbjct: 102 GANAGQTVFHVHAHVLS 118
>UniRef50_A3DF72 Cluster: Histidine triad (HIT) protein; n=2;
Clostridium thermocellum|Rep: Histidine triad (HIT)
protein - Clostridium thermocellum (strain ATCC 27405 /
DSM 1237)
Length = 114
Score = 38.7 bits (86), Expect = 0.11
Identities = 15/37 (40%), Positives = 24/37 (64%)
Frame = +2
Query: 5 VCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELL 115
V +DI PA+ H+L IPK HI +VK + ++ ++L
Sbjct: 25 VIAIKDINPAAPVHVLIIPKEHIANVKEINESNAQIL 61
>UniRef50_UPI000050FB45 Cluster: COG0537: Diadenosine tetraphosphate
(Ap4A) hydrolase and other HIT family hydrolases; n=1;
Brevibacterium linens BL2|Rep: COG0537: Diadenosine
tetraphosphate (Ap4A) hydrolase and other HIT family
hydrolases - Brevibacterium linens BL2
Length = 144
Score = 38.3 bits (85), Expect = 0.15
Identities = 15/30 (50%), Positives = 21/30 (70%)
Frame = +2
Query: 14 FRDIKPASRFHILTIPKRHIEDVKSLTSAD 103
F DI+P S H+L +PKRH D++ + SAD
Sbjct: 29 FMDIQPGSDGHLLVVPKRHSTDLRDIPSAD 58
>UniRef50_A7H3E9 Cluster: HIT family protein; n=11;
Campylobacter|Rep: HIT family protein - Campylobacter
jejuni subsp. doylei 269.97
Length = 121
Score = 38.3 bits (85), Expect = 0.15
Identities = 19/44 (43%), Positives = 26/44 (59%)
Frame = +2
Query: 14 FRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISREL 145
F DI P + HIL IPK+H +D + D EL+ +M S +EL
Sbjct: 29 FHDIAPKAPIHILIIPKKHFKDFQEF---DPELMAKMTSFIQEL 69
>UniRef50_A1VWA8 Cluster: Histidine triad (HIT) protein; n=5;
cellular organisms|Rep: Histidine triad (HIT) protein -
Polaromonas naphthalenivorans (strain CJ2)
Length = 133
Score = 38.3 bits (85), Expect = 0.15
Identities = 29/101 (28%), Positives = 47/101 (46%), Gaps = 11/101 (10%)
Frame = +2
Query: 29 PASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKN------NLSIEDARFGY 190
P S H L IPKRH+ +T+ ++E L ++ ++EL+++ N+ I D
Sbjct: 35 PVSPGHSLVIPKRHVRSFFEVTAPEREALFALLDRAKELVAEQHRPDGYNIGINDGA--- 91
Query: 191 HWPPFRSVKHLHLHTIA-----PESEMGFIGRVIFKKNSYW 298
++V HLH+H I G + VI +K YW
Sbjct: 92 --AAGQTVPHLHIHLIPRYDGDQLDPRGGVRWVIPEKADYW 130
>UniRef50_Q4N9V7 Cluster: Protein kinase C interacting protein 1,
putative; n=2; Theileria|Rep: Protein kinase C
interacting protein 1, putative - Theileria parva
Length = 180
Score = 38.3 bits (85), Expect = 0.15
Identities = 26/83 (31%), Positives = 43/83 (51%), Gaps = 4/83 (4%)
Frame = +2
Query: 5 VCVFRDIKPASRFHILTIPKR--HIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDA 178
V F DI+PAS HIL IPK + + T +++L M+ + + +NNL D
Sbjct: 91 VLAFYDIQPASPSHILIIPKEMDGLASLSDATERHEKVLGHMLVKAAHIAKENNLG--DF 148
Query: 179 RFGYHWPP--FRSVKHLHLHTIA 241
R + P ++V +LH+H ++
Sbjct: 149 RVVINSGPGALQTVFYLHMHLMS 171
>UniRef50_Q9V017 Cluster: Histidine triad (HIT) protein; n=4;
Thermococcaceae|Rep: Histidine triad (HIT) protein -
Pyrococcus abyssi
Length = 147
Score = 38.3 bits (85), Expect = 0.15
Identities = 22/78 (28%), Positives = 41/78 (52%), Gaps = 2/78 (2%)
Frame = +2
Query: 11 VFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDARFGY 190
+ D PA+ H+L +PKRH+ + +LT +K L + + ++ + L K L + G
Sbjct: 22 ILLDNYPANPGHLLVVPKRHVTSIGNLTEDEKLALLKGIELAVKAL-KRALKADGFNVGI 80
Query: 191 H--WPPFRSVKHLHLHTI 238
+ ++V H+H+H I
Sbjct: 81 NIGKAAGQTVDHIHIHVI 98
>UniRef50_Q8PVK5 Cluster: Hit-like protein; n=4;
Methanosarcinaceae|Rep: Hit-like protein -
Methanosarcina mazei (Methanosarcina frisia)
Length = 155
Score = 38.3 bits (85), Expect = 0.15
Identities = 26/82 (31%), Positives = 38/82 (46%), Gaps = 4/82 (4%)
Frame = +2
Query: 5 VCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLS--KNNLSIEDA 178
VC F DI PAS H L PK+H S T E R+ +R++ + + S E +
Sbjct: 30 VCAFLDIYPASEGHTLIAPKKHF---NSFTDMGAEDTARLFEAARKITAAVEKAFSAEGS 86
Query: 179 RFGYHWPPF--RSVKHLHLHTI 238
G + + V H+H+H I
Sbjct: 87 NIGINNGEVAGQEVPHVHVHVI 108
>UniRef50_O07817 Cluster: Protein hitA; n=7; Betaproteobacteria|Rep:
Protein hitA - Neisseria gonorrhoeae
Length = 107
Score = 38.3 bits (85), Expect = 0.15
Identities = 18/55 (32%), Positives = 29/55 (52%)
Frame = +2
Query: 2 EVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLS 166
E+ F+DI PA+ H+L IPK H + + + LL +MM E+ + L+
Sbjct: 24 EMVCFKDINPAAPLHLLLIPKVHFDSLAHAAPEHQPLLGKMMLKVPEIAKASGLT 78
>UniRef50_UPI000038E073 Cluster: hypothetical protein Faci_03000287;
n=1; Ferroplasma acidarmanus fer1|Rep: hypothetical
protein Faci_03000287 - Ferroplasma acidarmanus fer1
Length = 137
Score = 37.9 bits (84), Expect = 0.19
Identities = 24/76 (31%), Positives = 37/76 (48%), Gaps = 1/76 (1%)
Frame = +2
Query: 14 FRDIKPASRFHILTIPKRHIEDVKSLTSADK-ELLNRMMSISRELLSKNNLSIEDARFGY 190
F DI P S HIL IPK H +D+ + S E + + +I+ L K N++ +
Sbjct: 26 FLDIHPISNGHILVIPKEHYKDIYEMDSNILIETIKTVKAITGILKDKLNINAVNIMNSN 85
Query: 191 HWPPFRSVKHLHLHTI 238
++V H H+H I
Sbjct: 86 GEIANQTVFHYHIHVI 101
>UniRef50_A7H6R9 Cluster: Histidine triad (HIT) protein; n=14;
Bacteria|Rep: Histidine triad (HIT) protein -
Anaeromyxobacter sp. Fw109-5
Length = 114
Score = 37.9 bits (84), Expect = 0.19
Identities = 17/81 (20%), Positives = 36/81 (44%), Gaps = 2/81 (2%)
Frame = +2
Query: 2 EVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDAR 181
+ F D+ P + H+L +P++H+ + L D L+ ++ + + R
Sbjct: 24 DTVAFEDLNPQAPTHVLIVPRKHVATMVDLAPEDDALVGKLFRAGAAIAKARGIDGPGYR 83
Query: 182 --FGYHWPPFRSVKHLHLHTI 238
++ +SV H+HLH +
Sbjct: 84 VVMNHNRDAGQSVFHIHLHVL 104
>UniRef50_Q5TX49 Cluster: ENSANGP00000029056; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000029056 - Anopheles gambiae
str. PEST
Length = 153
Score = 37.9 bits (84), Expect = 0.19
Identities = 26/82 (31%), Positives = 41/82 (50%), Gaps = 3/82 (3%)
Frame = +2
Query: 2 EVCV-FRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISREL-LSKNNLSIE- 172
E C+ F D+ P + H L IPK I+ +++ T ELL ++ ++ +L SK
Sbjct: 64 EKCIAFNDVAPQAPVHFLVIPKNKIDKLENSTPNQTELLGHLLHVAGQLGKSKAPKGFRL 123
Query: 173 DARFGYHWPPFRSVKHLHLHTI 238
G H ++V H+HLH I
Sbjct: 124 VINNGDH--GCQTVYHIHLHVI 143
>UniRef50_A1AWF6 Cluster: Histidine triad (HIT) protein; n=1;
Candidatus Ruthia magnifica str. Cm (Calyptogena
magnifica)|Rep: Histidine triad (HIT) protein - Ruthia
magnifica subsp. Calyptogena magnifica
Length = 130
Score = 37.5 bits (83), Expect = 0.26
Identities = 27/102 (26%), Positives = 46/102 (45%), Gaps = 7/102 (6%)
Frame = +2
Query: 14 FRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDARFGYH 193
F D P S H L +PKRH+ +T ++ + + + S+ +L + S + G +
Sbjct: 25 FLDSYPVSPGHTLIVPKRHVATYFDITEQEQNAIAKAIQKSKLILDE-EFSPDGFNIGMN 83
Query: 194 WPPF--RSVKHLHLHTIA-----PESEMGFIGRVIFKKNSYW 298
+S+ HLH+H I ++ G + VI K YW
Sbjct: 84 NGEVAGQSIMHLHVHMIPRYKNDVKNPKGGVRWVISNKADYW 125
>UniRef50_P73481 Cluster: Uncharacterized HIT-like protein slr1234;
n=8; cellular organisms|Rep: Uncharacterized HIT-like
protein slr1234 - Synechocystis sp. (strain PCC 6803)
Length = 114
Score = 37.5 bits (83), Expect = 0.26
Identities = 20/81 (24%), Positives = 43/81 (53%), Gaps = 2/81 (2%)
Frame = +2
Query: 2 EVCV-FRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDA 178
++C+ F+D+ P + H+L IPK+ + + + T D LL ++ ++E+ + + +
Sbjct: 24 DLCLAFKDVNPQAPVHVLLIPKKPLPQLSAATPEDHALLGHLLLKAKEVAADLGIGDQFR 83
Query: 179 RFGYHWPPF-RSVKHLHLHTI 238
+ ++V HLHLH +
Sbjct: 84 LVINNGAEVGQTVFHLHLHIL 104
>UniRef50_A6WDH4 Cluster: Histidine triad (HIT) protein; n=2;
Actinomycetales|Rep: Histidine triad (HIT) protein -
Kineococcus radiotolerans SRS30216
Length = 121
Score = 37.1 bits (82), Expect = 0.34
Identities = 20/78 (25%), Positives = 36/78 (46%)
Frame = +2
Query: 5 VCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDARF 184
V F D+ P + H+L IP+ E+V L +A L R++ +++ + + F
Sbjct: 34 VVAFEDVNPQAPVHVLVIPRERHENVAQLAAAAPATLARLVEVAQRIADERCGGEYRLVF 93
Query: 185 GYHWPPFRSVKHLHLHTI 238
+SV H+H H +
Sbjct: 94 NTGTAVGQSVFHVHGHVL 111
>UniRef50_A6FN65 Cluster: HIT family protein; n=1; Roseobacter sp.
AzwK-3b|Rep: HIT family protein - Roseobacter sp.
AzwK-3b
Length = 332
Score = 37.1 bits (82), Expect = 0.34
Identities = 29/106 (27%), Positives = 48/106 (45%), Gaps = 8/106 (7%)
Frame = +2
Query: 2 EVCV-FRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDA 178
E+CV RD P + H L IPKRH+ D L + + M+ R ++ + +++
Sbjct: 227 ELCVAIRDGFPVTPMHTLIIPKRHVADYFDLYQPELNAIQTMLVEQRRQITAADDTVKGF 286
Query: 179 RFGYH--WPPFRSVKHLHLHTIA-----PESEMGFIGRVIFKKNSY 295
G + +++ H+H+H I E G + VI K SY
Sbjct: 287 NVGVNAGSDAGQTIFHVHVHLIPRRAGDVERPRGGVRGVIPDKQSY 332
>UniRef50_Q5WBH5 Cluster: Histidine triad protein involved in
cell-cycle regulation; n=1; Bacillus clausii
KSM-K16|Rep: Histidine triad protein involved in
cell-cycle regulation - Bacillus clausii (strain
KSM-K16)
Length = 134
Score = 36.7 bits (81), Expect = 0.45
Identities = 23/79 (29%), Positives = 42/79 (53%)
Frame = +2
Query: 2 EVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDAR 181
+ F DI+P + H+L IPKRH E + +L ++E ++ M ++ R L + + ++ +
Sbjct: 23 QAIAFLDIQPINPGHMLVIPKRHQEALHTL--GEQEYIDVMKAV-RRLSKQVDDTLRPKK 79
Query: 182 FGYHWPPFRSVKHLHLHTI 238
G F HLH+H +
Sbjct: 80 VGVAIAGFDQA-HLHVHIV 97
>UniRef50_P64382 Cluster: Uncharacterized HIT-like protein HP_0404;
n=4; Helicobacter|Rep: Uncharacterized HIT-like protein
HP_0404 - Helicobacter pylori (Campylobacter pylori)
Length = 104
Score = 36.7 bits (81), Expect = 0.45
Identities = 23/78 (29%), Positives = 38/78 (48%), Gaps = 2/78 (2%)
Frame = +2
Query: 14 FRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDARF--G 187
F DI P ++ H L IPK+ I+D +T EL+ +M S E++ K + + +
Sbjct: 26 FYDINPKAKVHALVIPKQSIQDFNGIT---PELMAQMTSFIFEVVEKLGIKEKGYKLLTN 82
Query: 188 YHWPPFRSVKHLHLHTIA 241
+ V HLH H ++
Sbjct: 83 VGKNAGQEVMHLHFHILS 100
>UniRef50_Q9PK09 Cluster: Uncharacterized HIT-like protein TC_0664;
n=9; Chlamydiales|Rep: Uncharacterized HIT-like protein
TC_0664 - Chlamydia muridarum
Length = 126
Score = 36.7 bits (81), Expect = 0.45
Identities = 25/79 (31%), Positives = 39/79 (49%), Gaps = 3/79 (3%)
Frame = +2
Query: 11 VFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDAR--- 181
V +D P + H+L IPK+HIE ++ + S D LL+ I + L + IE+
Sbjct: 41 VIKDKFPQAPVHLLIIPKKHIEKLQDMQSDDFSLLSEAGKIIQ--LMARDFGIENGYRVV 98
Query: 182 FGYHWPPFRSVKHLHLHTI 238
+SV HLH+H +
Sbjct: 99 INNGLEGGQSVFHLHIHLL 117
>UniRef50_Q5KLA4 Cluster: Hydrolase, putative; n=2; Dikarya|Rep:
Hydrolase, putative - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 140
Score = 35.9 bits (79), Expect = 0.78
Identities = 22/85 (25%), Positives = 36/85 (42%)
Frame = +2
Query: 5 VCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDARF 184
V F D+ P +R H L IPK+H + T E + ++ ++L + +
Sbjct: 28 VFAFMDVGPIARGHCLVIPKQH---AATFTELPDEAMVDILPTCKKLAAATGAENYNILQ 84
Query: 185 GYHWPPFRSVKHLHLHTIAPESEMG 259
P + V H+H H I +E G
Sbjct: 85 NNGRPAHQVVDHVHFHVIPKPAEAG 109
>UniRef50_Q67LQ3 Cluster: HIT family protein; n=1; Symbiobacterium
thermophilum|Rep: HIT family protein - Symbiobacterium
thermophilum
Length = 339
Score = 35.1 bits (77), Expect = 1.4
Identities = 17/38 (44%), Positives = 24/38 (63%), Gaps = 1/38 (2%)
Frame = +2
Query: 14 FRDIKPASRFHILTIPKRHIEDVKSLTS-ADKELLNRM 124
F +I+ A+ H+L IPKRH+E V L S D +L R+
Sbjct: 224 FMNIRQANPGHVLVIPKRHVEQVFDLDSDLDSDLAGRL 261
>UniRef50_Q2LVF0 Cluster: Hit family hydrolase; n=1; Syntrophus
aciditrophicus SB|Rep: Hit family hydrolase - Syntrophus
aciditrophicus (strain SB)
Length = 116
Score = 35.1 bits (77), Expect = 1.4
Identities = 19/80 (23%), Positives = 36/80 (45%), Gaps = 2/80 (2%)
Frame = +2
Query: 5 VCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDAR- 181
V F DI P + H++ +PKRHI ++ L MM+ ++++ + + R
Sbjct: 26 VLAFEDIHPMAPVHVVVVPKRHISTFMDVSDDTMAYLMSMMTAAQKIAKLKAIDEKGFRT 85
Query: 182 -FGYHWPPFRSVKHLHLHTI 238
+ + HLH+H +
Sbjct: 86 VINCKEEGGQVIFHLHMHLL 105
>UniRef50_A5KT99 Cluster: Histidine triad (HIT) protein; n=2;
candidate division TM7 genomosp. GTL1|Rep: Histidine
triad (HIT) protein - candidate division TM7 genomosp.
GTL1
Length = 497
Score = 35.1 bits (77), Expect = 1.4
Identities = 20/67 (29%), Positives = 36/67 (53%), Gaps = 2/67 (2%)
Frame = +2
Query: 44 HILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDARFGYH--WPPFRSVK 217
H++ IP+RH+ K LTS + E + + M I+++++ K I+ +F +V
Sbjct: 61 HLMIIPRRHVVSPKELTSLEWETIRKFMYIAKKII-KQVHGIKGVQFVQKDGLDAQSTVG 119
Query: 218 HLHLHTI 238
H+H H I
Sbjct: 120 HVHYHGI 126
>UniRef50_Q8K9I9 Cluster: Uncharacterized HIT-like protein BUsg_345;
n=4; Enterobacteriaceae|Rep: Uncharacterized HIT-like
protein BUsg_345 - Buchnera aphidicola subsp. Schizaphis
graminum
Length = 115
Score = 35.1 bits (77), Expect = 1.4
Identities = 18/83 (21%), Positives = 38/83 (45%), Gaps = 2/83 (2%)
Frame = +2
Query: 5 VCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDAR- 181
V F DI P + HI+ IP I+ + + +K + M+ I+ ++ +S + +
Sbjct: 27 VTAFEDIAPKAPIHIIVIPNIFIKTLNDINQKNKNIFAHMLYIAVKIAKNKKISEDGYKI 86
Query: 182 -FGYHWPPFRSVKHLHLHTIAPE 247
+ + + +LH+H + E
Sbjct: 87 VMNCNKNGGQEINYLHMHLLGGE 109
>UniRef50_Q65J74 Cluster: Putative uncharacterized protein; n=1;
Bacillus licheniformis ATCC 14580|Rep: Putative
uncharacterized protein - Bacillus licheniformis (strain
DSM 13 / ATCC 14580)
Length = 142
Score = 34.7 bits (76), Expect = 1.8
Identities = 20/80 (25%), Positives = 34/80 (42%), Gaps = 2/80 (2%)
Frame = +2
Query: 5 VCVFRDIKPASRFHILTIPKRHIEDVKSLTSA--DKELLNRMMSISRELLSKNNLSIEDA 178
V F DI P + H L IP +HIE + + E+++ ++ + + L+
Sbjct: 29 VTAFLDINPVTNGHTLIIPNKHIERLDHINDPHLSNEIMDSLIKVPQLLIQSGICDDYTI 88
Query: 179 RFGYHWPPFRSVKHLHLHTI 238
+ +KHLH H I
Sbjct: 89 LSDNGHFAQQDIKHLHFHVI 108
>UniRef50_Q970Y2 Cluster: 141aa long hypothetical histidine triad
nucleotide-binding protein; n=1; Sulfolobus
tokodaii|Rep: 141aa long hypothetical histidine triad
nucleotide-binding protein - Sulfolobus tokodaii
Length = 141
Score = 34.7 bits (76), Expect = 1.8
Identities = 22/82 (26%), Positives = 39/82 (47%), Gaps = 3/82 (3%)
Frame = +2
Query: 2 EVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISREL---LSKNNLSIE 172
E+ F DI P ++ H+L IPK H E++ KE L +++ + +++ L K
Sbjct: 26 EIMAFLDINPVNKGHVLVIPKDHYENI---FDVPKEKLGKVIEVVQKVAIALRKMGADGV 82
Query: 173 DARFGYHWPPFRSVKHLHLHTI 238
+ + + HLH+H I
Sbjct: 83 NIVSNNGKAAEQHIFHLHIHVI 104
>UniRef50_A1RXN8 Cluster: Histidine triad (HIT) protein; n=1;
Thermofilum pendens Hrk 5|Rep: Histidine triad (HIT)
protein - Thermofilum pendens (strain Hrk 5)
Length = 167
Score = 34.7 bits (76), Expect = 1.8
Identities = 23/82 (28%), Positives = 38/82 (46%), Gaps = 3/82 (3%)
Frame = +2
Query: 2 EVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDAR 181
++ V + P + H+L P RH+ D L+ + L + +S+S ELL K LS +
Sbjct: 46 KIIVMLNRYPYNTGHLLVAPTRHVADFSQLSDEELFSLAKAVSLSLELL-KKALSPDGFN 104
Query: 182 FGYHWPPFRSV---KHLHLHTI 238
G + HLH+H +
Sbjct: 105 VGVNLGRVAGAGLESHLHVHVV 126
>UniRef50_Q88TZ2 Cluster: Cell-cycle regulation histidine triad
protein; n=4; Lactobacillales|Rep: Cell-cycle regulation
histidine triad protein - Lactobacillus plantarum
Length = 122
Score = 34.3 bits (75), Expect = 2.4
Identities = 22/77 (28%), Positives = 37/77 (48%), Gaps = 2/77 (2%)
Frame = +2
Query: 14 FRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDARFGYH 193
F D KP S H+L IPK H + +A + + +++ ++ L +N + G +
Sbjct: 21 FFDKKPVSPGHLLIIPKAHYATYFDVPTATRNAMLALLTQAKAYLDAHN-HPDGYNIGIN 79
Query: 194 WPPF--RSVKHLHLHTI 238
P ++V H HLH I
Sbjct: 80 VDPAAGQTVMHCHLHLI 96
>UniRef50_A7BYS1 Cluster: HIT family protein; n=2;
Proteobacteria|Rep: HIT family protein - Beggiatoa sp.
PS
Length = 125
Score = 34.3 bits (75), Expect = 2.4
Identities = 25/79 (31%), Positives = 34/79 (43%), Gaps = 1/79 (1%)
Frame = +2
Query: 5 VCVFRDIKPASRFHILTIPKRHIEDVKSLTSAD-KELLNRMMSISRELLSKNNLSIEDAR 181
V RD P S H L IPKRHI + T+ + + LLN + EL +
Sbjct: 22 VFTIRDGFPISSAHTLIIPKRHIASLFDATNKEQRALLNALQFTKTELDQIYKPDGYNIG 81
Query: 182 FGYHWPPFRSVKHLHLHTI 238
++V HLH+H I
Sbjct: 82 LNDGLAAGQTVMHLHIHLI 100
>UniRef50_A7BDL4 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 148
Score = 34.3 bits (75), Expect = 2.4
Identities = 24/85 (28%), Positives = 39/85 (45%), Gaps = 1/85 (1%)
Frame = +2
Query: 2 EVCV-FRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDA 178
+VCV F I+P S H+L +P+ + + T A ++ +M+++R + +
Sbjct: 22 DVCVAFATIEPTSPGHVLVVPRTAYD---AWTDAPSDVAAHLMTVARTIGLAQKAAFGVP 78
Query: 179 RFGYHWPPFRSVKHLHLHTIAPESE 253
R G F V H HLH I E
Sbjct: 79 RAGLAIAGF-EVPHTHLHVIPLRDE 102
>UniRef50_Q4DJ40 Cluster: Adenosine 5'-monophosphoramidase,
putative; n=6; Trypanosomatidae|Rep: Adenosine
5'-monophosphoramidase, putative - Trypanosoma cruzi
Length = 141
Score = 34.3 bits (75), Expect = 2.4
Identities = 26/87 (29%), Positives = 40/87 (45%), Gaps = 4/87 (4%)
Frame = +2
Query: 5 VCVFRDIKPASRFHILTIPKRHIE---DVKSLTSADKELLNRMMSISRELLSKNNLSIE- 172
V F DI P SR H+L +PK H E V+ T+AD ++ M I+R + + +
Sbjct: 25 VLAFVDINPLSRGHLLIVPKAHAEFLHQVEPETAADLGVM--MAKIARVVAGEGEPKTQY 82
Query: 173 DARFGYHWPPFRSVKHLHLHTIAPESE 253
+ + V H+H H I +E
Sbjct: 83 NVLQNNGKLAHQEVPHVHFHIIPKRNE 109
>UniRef50_Q58276 Cluster: Uncharacterized HIT-like protein MJ0866;
n=1; Methanocaldococcus jannaschii|Rep: Uncharacterized
HIT-like protein MJ0866 - Methanococcus jannaschii
Length = 129
Score = 34.3 bits (75), Expect = 2.4
Identities = 23/80 (28%), Positives = 35/80 (43%), Gaps = 2/80 (2%)
Frame = +2
Query: 5 VCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISR--ELLSKNNLSIEDA 178
V F DI P ++ H L +PK+H E + D EL N + + + E+L K +
Sbjct: 23 VLAFLDINPRNKGHTLVVPKKHYERFDEM--PDDELCNFIKGVKKTVEVLKKLGFDGYNI 80
Query: 179 RFGYHWPPFRSVKHLHLHTI 238
+ V H+H H I
Sbjct: 81 VNNNGRVAGQEVNHVHFHII 100
>UniRef50_A0LCF6 Cluster: Histidine triad (HIT) protein; n=3;
Bacteria|Rep: Histidine triad (HIT) protein -
Magnetococcus sp. (strain MC-1)
Length = 117
Score = 33.9 bits (74), Expect = 3.1
Identities = 19/80 (23%), Positives = 37/80 (46%), Gaps = 2/80 (2%)
Frame = +2
Query: 5 VCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDAR- 181
V FRDI P + H+L IPK+HI + + + ++ +M + + ++ + R
Sbjct: 26 VLAFRDIHPQAPEHVLVIPKQHIATLDDVQVQARAVMGHLMERTAHVARLIGVAEKGYRT 85
Query: 182 -FGYHWPPFRSVKHLHLHTI 238
+ V H+H+H +
Sbjct: 86 LINTRGDGGQEVYHIHVHIL 105
>UniRef50_Q10MW4 Cluster: Basic helix-loop-helix, putative,
expressed; n=4; Oryza sativa|Rep: Basic
helix-loop-helix, putative, expressed - Oryza sativa
subsp. japonica (Rice)
Length = 572
Score = 33.9 bits (74), Expect = 3.1
Identities = 28/86 (32%), Positives = 43/86 (50%), Gaps = 7/86 (8%)
Frame = +2
Query: 11 VFRDIKPASRFHILTIPKRHIEDVKSLTSADKE---LLNRMMSISRELLSKNNLSIEDA- 178
V D+ P ++ H+L + ++ + + SL KE LL RM S + K ED+
Sbjct: 397 VLNDLYPKAKRHVLVVSRK--DGLDSLADVKKEHLPLLRRMHSAGVKWAQK--FLEEDSS 452
Query: 179 ---RFGYHWPPFRSVKHLHLHTIAPE 247
R GYH P S++ LHLH I+ +
Sbjct: 453 LVFRLGYHSVP--SMRQLHLHIISQD 476
>UniRef50_Q74MW7 Cluster: NEQ519; n=1; Nanoarchaeum equitans|Rep:
NEQ519 - Nanoarchaeum equitans
Length = 129
Score = 33.9 bits (74), Expect = 3.1
Identities = 22/85 (25%), Positives = 40/85 (47%), Gaps = 2/85 (2%)
Frame = +2
Query: 5 VCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDARF 184
V DI P ++ H L IPK+H+ +K L+ +E ++ + ++++ K D
Sbjct: 23 VIAILDIYPMAKGHTLVIPKKHVTRLKELS---EEEAKKLFAGLKKVIEKIEKISPDYNI 79
Query: 185 GYHWPP--FRSVKHLHLHTIAPESE 253
+ P + + HLH+H I E
Sbjct: 80 IINQGPKAGQEIDHLHIHIIPRTGE 104
>UniRef50_O07513 Cluster: Protein hit; n=16; Bacillaceae|Rep:
Protein hit - Bacillus subtilis
Length = 145
Score = 33.9 bits (74), Expect = 3.1
Identities = 27/85 (31%), Positives = 39/85 (45%), Gaps = 7/85 (8%)
Frame = +2
Query: 5 VCVFRDIKPASRFHILTIPKRHIEDVKSLT-SADKELLNRMMSISR------ELLSKNNL 163
V F DI ++ H L IPK HIE+V T K+ + + I+R E + N L
Sbjct: 28 VLAFLDISQVTKGHTLVIPKTHIENVYEFTDELAKQYFHAVPKIARAIRDEFEPIGLNTL 87
Query: 164 SIEDARFGYHWPPFRSVKHLHLHTI 238
+ + G +SV H H+H I
Sbjct: 88 NNNGEKAG------QSVFHYHMHII 106
>UniRef50_Q9PQL9 Cluster: Probable HIT protein; n=1; Ureaplasma
parvum|Rep: Probable HIT protein - Ureaplasma parvum
(Ureaplasma urealyticum biotype 1)
Length = 152
Score = 33.5 bits (73), Expect = 4.2
Identities = 30/92 (32%), Positives = 44/92 (47%), Gaps = 6/92 (6%)
Frame = +2
Query: 20 DIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISREL-LSKNNLSIEDARFGYHW 196
DI+PAS H+L IPK+H + SLT D L+ MM +++ + + F Y
Sbjct: 30 DIQPASDGHMLIIPKKHYRNF-SLT--DPIYLDGMMRLAKNMTFVLEEVFPNVLGFNYLM 86
Query: 197 PPFRS----VKHLHLHTIAPESE-MGFIGRVI 277
S + H HLH I +S GF+ + I
Sbjct: 87 NSNSSAGQVIMHTHLHIIPKQSNGRGFVFKAI 118
>UniRef50_Q6A7Y9 Cluster: Putative cell-cycle regulation histidine
triad protein; n=1; Propionibacterium acnes|Rep:
Putative cell-cycle regulation histidine triad protein -
Propionibacterium acnes
Length = 136
Score = 33.5 bits (73), Expect = 4.2
Identities = 21/75 (28%), Positives = 32/75 (42%)
Frame = +2
Query: 14 FRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDARFGYH 193
F DI+P H L IP+RH+ V + + ++R L+ S +
Sbjct: 27 FLDIEPFQDGHTLVIPRRHVTSVLDDDGELGRISPMVTKVARRLVDSLGASGVNVVSNAG 86
Query: 194 WPPFRSVKHLHLHTI 238
+SV HLH+H I
Sbjct: 87 EVAGQSVHHLHVHVI 101
>UniRef50_Q4K6N7 Cluster: HIT family protein; n=1; Pseudomonas
fluorescens Pf-5|Rep: HIT family protein - Pseudomonas
fluorescens (strain Pf-5 / ATCC BAA-477)
Length = 158
Score = 33.5 bits (73), Expect = 4.2
Identities = 23/97 (23%), Positives = 44/97 (45%), Gaps = 5/97 (5%)
Frame = +2
Query: 2 EVCV-FRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDA 178
E C+ F D+ P H+L IP++H+E ++ L ++ L ++ + +E
Sbjct: 22 EHCMAFMDVHPLGEGHLLLIPQQHVEKLEQLPGFIRQHLYQVFDGLLAAQRRAGYGVEGT 81
Query: 179 RFGYH--WPPFRSVKHLHLHTIAPE--SEMGFIGRVI 277
+ + + H HLH I + +GF GR++
Sbjct: 82 HLLVNDGRATNQHIPHAHLHLIPRKRGDGLGFAGRLL 118
>UniRef50_Q023M8 Cluster: Histidine triad (HIT) protein; n=2;
Bacteria|Rep: Histidine triad (HIT) protein - Solibacter
usitatus (strain Ellin6076)
Length = 146
Score = 33.5 bits (73), Expect = 4.2
Identities = 24/91 (26%), Positives = 41/91 (45%), Gaps = 2/91 (2%)
Frame = +2
Query: 2 EVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLS--KNNLSIED 175
E+ F D +P H L IP+ H E +LT ++ + + + +R L S + E
Sbjct: 30 ELVAFLDTRPLFPGHCLLIPRPHFE---TLTELPEDRVTPLFAAARMLTSAVETAFDAEG 86
Query: 176 ARFGYHWPPFRSVKHLHLHTIAPESEMGFIG 268
+ + +SV HLH+H + + G G
Sbjct: 87 SFVAINNRVSQSVPHLHVHIVPRRRKDGLKG 117
>UniRef50_Q5CSR7 Cluster: Histidine triad (HIT) family zinc binding
protein; n=3; Alveolata|Rep: Histidine triad (HIT)
family zinc binding protein - Cryptosporidium parvum
Iowa II
Length = 130
Score = 33.5 bits (73), Expect = 4.2
Identities = 22/84 (26%), Positives = 42/84 (50%), Gaps = 5/84 (5%)
Frame = +2
Query: 2 EVCV-FRDIKPASRFHILTIPKRH--IEDVKSLTSADKELLNRMMSISRELLSKNNLSIE 172
++C+ F DI P + H L +PK+ + + T KE+L +M ++ + L ++
Sbjct: 39 DLCISFHDINPVAPVHALLVPKKRSGLTRLSKATETHKEILGHLM--TKVPVVAKLLDLD 96
Query: 173 DARFGYH--WPPFRSVKHLHLHTI 238
D R + ++V HLH+H +
Sbjct: 97 DFRIVINDGESSCQTVFHLHIHIL 120
>UniRef50_A2E0S0 Cluster: HIT domain containing protein; n=1;
Trichomonas vaginalis G3|Rep: HIT domain containing
protein - Trichomonas vaginalis G3
Length = 135
Score = 33.5 bits (73), Expect = 4.2
Identities = 24/78 (30%), Positives = 40/78 (51%), Gaps = 3/78 (3%)
Frame = +2
Query: 14 FRDIKPASRFHILTIPKRHIEDVKSLTSADK-ELLNRMMSISRELLSKNNLSIEDARFGY 190
F +++PA H+L PKR ++ LT A+K +LLN + R+ + K ++ E
Sbjct: 28 FVNLRPACEGHVLISPKRVVQFFDLLTDAEKLDLLNTATHV-RDTM-KASMHTEGCAMTI 85
Query: 191 HWPPF--RSVKHLHLHTI 238
P ++V H+H H I
Sbjct: 86 QDGPAAGQTVPHVHFHVI 103
>UniRef50_Q0LZX4 Cluster: Histidine triad (HIT) protein precursor;
n=2; Alphaproteobacteria|Rep: Histidine triad (HIT)
protein precursor - Caulobacter sp. K31
Length = 455
Score = 33.1 bits (72), Expect = 5.5
Identities = 22/81 (27%), Positives = 38/81 (46%), Gaps = 2/81 (2%)
Frame = +2
Query: 2 EVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISREL--LSKNNLSIED 175
+V F D PA H+L I K ++L + L+R+M+++ + + L +E
Sbjct: 341 QVLAFMDYAPAEPGHVLVISKT--SKARNLLEISPQDLSRIMAVAARVGQAQVDGLGVEG 398
Query: 176 ARFGYHWPPFRSVKHLHLHTI 238
+ +SV HLH+H I
Sbjct: 399 FTIVQNNGVGQSVPHLHIHVI 419
>UniRef50_A7FTJ1 Cluster: HIT family protein; n=4; Clostridium
botulinum|Rep: HIT family protein - Clostridium
botulinum (strain ATCC 19397 / Type A)
Length = 142
Score = 33.1 bits (72), Expect = 5.5
Identities = 21/78 (26%), Positives = 35/78 (44%), Gaps = 2/78 (2%)
Frame = +2
Query: 5 VCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLS--KNNLSIEDA 178
VC F +P + H+L PK+H D L D E +M +S+ ++ K+ +
Sbjct: 29 VCCFLAEEPINEGHMLIAPKKHYLD---LDQMDDETAIEIMKVSKIMVKVLKDTYKSDGY 85
Query: 179 RFGYHWPPFRSVKHLHLH 232
+ F +V H H+H
Sbjct: 86 SIMQNGGSFNNVGHYHMH 103
>UniRef50_A5UUJ2 Cluster: Putative uncharacterized protein
precursor; n=4; Chloroflexaceae|Rep: Putative
uncharacterized protein precursor - Roseiflexus sp. RS-1
Length = 113
Score = 33.1 bits (72), Expect = 5.5
Identities = 15/48 (31%), Positives = 27/48 (56%)
Frame = +2
Query: 20 DIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNL 163
+I+P ILT+PK H + +T + L + S+ REL+ +++L
Sbjct: 56 EIEPGDTLEILTVPKTHGQTNGEITYPSRIRLTKASSLRRELVRRSSL 103
>UniRef50_A3EUM2 Cluster: Histidine triad protein; n=1;
Leptospirillum sp. Group II UBA|Rep: Histidine triad
protein - Leptospirillum sp. Group II UBA
Length = 118
Score = 33.1 bits (72), Expect = 5.5
Identities = 21/77 (27%), Positives = 40/77 (51%), Gaps = 4/77 (5%)
Frame = +2
Query: 20 DIKPASRFHILTIPKRHIEDVKSLTSAD-KELL-NRMMSISRELLSKNNLSIEDARFGYH 193
D+ P + FH L + +RH+ D+ +L D EL+ ++M ++ + LS + R +
Sbjct: 32 DVNPQAPFHALVLSRRHVGDMATLLKVDGGELVAGKLMRMAVNVARDAGLSPDGYRVVIN 91
Query: 194 W--PPFRSVKHLHLHTI 238
++V HLH+H +
Sbjct: 92 TGNNGGQTVAHLHVHVL 108
>UniRef50_Q8YU88 Cluster: All2466 protein; n=5; Cyanobacteria|Rep:
All2466 protein - Anabaena sp. (strain PCC 7120)
Length = 284
Score = 32.7 bits (71), Expect = 7.3
Identities = 15/40 (37%), Positives = 23/40 (57%)
Frame = +2
Query: 29 PASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELL 148
P S+ HIL IPKRH+ D L ++ M++ ++E L
Sbjct: 192 PISKGHILVIPKRHVSDYFELPQKEQSACWLMVNKAQEFL 231
>UniRef50_Q7M8Z0 Cluster: HIT-FAMILY PROTEIN; n=12;
Epsilonproteobacteria|Rep: HIT-FAMILY PROTEIN -
Wolinella succinogenes
Length = 120
Score = 32.7 bits (71), Expect = 7.3
Identities = 22/79 (27%), Positives = 36/79 (45%), Gaps = 4/79 (5%)
Frame = +2
Query: 14 FRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDARF--- 184
F DI P + H+L IPK+ +S D + M S +E+ K L +++A +
Sbjct: 26 FHDINPKAPIHVLAIPKK---CARSFQEVDPSWMGGMTSFIQEVARK--LGLDEAGYRVI 80
Query: 185 -GYHWPPFRSVKHLHLHTI 238
+ + V HLH H +
Sbjct: 81 TNIGYDGGQEVPHLHFHIL 99
>UniRef50_Q6NFF8 Cluster: HIT family protein; n=4;
Corynebacterium|Rep: HIT family protein -
Corynebacterium diphtheriae
Length = 141
Score = 32.7 bits (71), Expect = 7.3
Identities = 21/85 (24%), Positives = 41/85 (48%)
Frame = +2
Query: 5 VCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDARF 184
+ F I+P + H+L +P +++V T + EL + +++ ++ + + R
Sbjct: 24 IVAFLTIEPLAYGHVLVVP---VKEVDKWTDLEPELWTELNAVALKVGQAVVSAFDAPRA 80
Query: 185 GYHWPPFRSVKHLHLHTIAPESEMG 259
GY F V H H+H + P +MG
Sbjct: 81 GYIIAGF-DVPHTHIH-VFPAGKMG 103
>UniRef50_Q03D63 Cluster: Diadenosine tetraphosphate (Ap4A)
hydrolase related HIT family hydrolase; n=1; Pediococcus
pentosaceus ATCC 25745|Rep: Diadenosine tetraphosphate
(Ap4A) hydrolase related HIT family hydrolase -
Pediococcus pentosaceus (strain ATCC 25745 / 183-1w)
Length = 132
Score = 32.7 bits (71), Expect = 7.3
Identities = 19/76 (25%), Positives = 34/76 (44%), Gaps = 1/76 (1%)
Frame = +2
Query: 14 FRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELL-SKNNLSIEDARFGY 190
F D P S+ H L +PKRH+ + L ++ + ++ ++ +L K +
Sbjct: 27 FLDFYPVSKGHTLIVPKRHVRQLWELNEEERHAIFTLVEKNKAILDQKYQPDGYNVVVNS 86
Query: 191 HWPPFRSVKHLHLHTI 238
+SV H H+H I
Sbjct: 87 GAAAGQSVFHCHIHLI 102
>UniRef50_Q4P3W7 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 240
Score = 32.7 bits (71), Expect = 7.3
Identities = 15/52 (28%), Positives = 23/52 (44%)
Frame = +2
Query: 14 FRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSI 169
F DI P R H L +PK+H+E V L L+ + + + K +
Sbjct: 78 FLDILPLRRGHTLVVPKKHVEQVSHLDQQTAAWLSNALVQTTRAVGKGEFHV 129
>UniRef50_Q4LEG8 Cluster: Histidine triad protein; n=1; uncultured
crenarchaeote 45-H-12|Rep: Histidine triad protein -
uncultured crenarchaeote 45-H-12
Length = 161
Score = 32.7 bits (71), Expect = 7.3
Identities = 20/77 (25%), Positives = 35/77 (45%), Gaps = 1/77 (1%)
Frame = +2
Query: 11 VFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMM-SISRELLSKNNLSIEDARFG 187
VF D P S H L IPKRH + + S D +L ++ +++ +++ N
Sbjct: 38 VFMDKYPISNGHTLVIPKRHYTTILDMESRDVGMLFALVHKVAKAVVNALNAQGFSIAQN 97
Query: 188 YHWPPFRSVKHLHLHTI 238
+ V H+H+H +
Sbjct: 98 NGKVAHQVVPHVHVHIV 114
>UniRef50_P42856 Cluster: 14 kDa zinc-binding protein; n=11;
Eukaryota|Rep: 14 kDa zinc-binding protein - Zea mays
(Maize)
Length = 128
Score = 32.7 bits (71), Expect = 7.3
Identities = 24/84 (28%), Positives = 44/84 (52%), Gaps = 5/84 (5%)
Frame = +2
Query: 2 EVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADK---ELLNRMMSISRELLSKNNLSIE 172
+V FRDI P + HIL IPK + + L A++ E+L ++ +++ + + L +
Sbjct: 37 KVLAFRDINPQAPTHILIIPKVK-DGLTGLAKAEERHIEILGYLLYVAKVVAKQEGLE-D 94
Query: 173 DARFGYHWPP--FRSVKHLHLHTI 238
R + P +SV H+H+H +
Sbjct: 95 GYRVVINDGPSGCQSVYHIHVHLL 118
>UniRef50_UPI0000E46DB2 Cluster: PREDICTED: similar to RE33408p;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
similar to RE33408p - Strongylocentrotus purpuratus
Length = 579
Score = 32.3 bits (70), Expect = 9.6
Identities = 18/59 (30%), Positives = 33/59 (55%), Gaps = 2/59 (3%)
Frame = +2
Query: 2 EVCVFR-DIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSK-NNLSIE 172
EV FR DI+PA + P+R+ DV S + +E + R++S ++ + NN+ ++
Sbjct: 88 EVKFFRKDIEPAPQLSQFNDPERYFTDVSSFSGVPREAVGRIISAILQITTMLNNIRLQ 146
>UniRef50_Q74I95 Cluster: Hit protein; n=5; Lactobacillus|Rep: Hit
protein - Lactobacillus johnsonii
Length = 144
Score = 32.3 bits (70), Expect = 9.6
Identities = 20/86 (23%), Positives = 39/86 (45%), Gaps = 2/86 (2%)
Frame = +2
Query: 2 EVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDAR 181
+V F DI ++ H L IPK+H+ + + D + + + + + K++ +I+
Sbjct: 28 DVKAFLDISQVTKGHTLIIPKKHLVNFFDYSQEDAARFLQYIPVIAQAIKKSDPTIKGLN 87
Query: 182 FGYHWPPF--RSVKHLHLHTIAPESE 253
+ + V H H+H I SE
Sbjct: 88 VEVNNGEIAGQVVMHSHIHLIPRRSE 113
>UniRef50_Q2BQP2 Cluster: HIT domain protein; n=1; Neptuniibacter
caesariensis|Rep: HIT domain protein - Neptuniibacter
caesariensis
Length = 84
Score = 32.3 bits (70), Expect = 9.6
Identities = 15/44 (34%), Positives = 25/44 (56%)
Frame = +2
Query: 14 FRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISREL 145
F+D P + H+L IP +HI ++ L A L+ ++ SR+L
Sbjct: 24 FKDRAPKAPVHLLVIPCQHIRNLNDLREAGAALVAHLVLKSRKL 67
>UniRef50_A0LM74 Cluster: Histidine triad (HIT) protein; n=1;
Syntrophobacter fumaroxidans MPOB|Rep: Histidine triad
(HIT) protein - Syntrophobacter fumaroxidans (strain DSM
10017 / MPOB)
Length = 136
Score = 32.3 bits (70), Expect = 9.6
Identities = 22/87 (25%), Positives = 34/87 (39%), Gaps = 1/87 (1%)
Frame = +2
Query: 5 VCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKE-LLNRMMSISRELLSKNNLSIEDAR 181
V F DI P +R H L +PKRH + + D E + + + S +
Sbjct: 25 VLSFLDINPVARGHALVVPKRHYSTLFHIPPEDLEACIVAAKRVGAAVFKGVGASGLNVL 84
Query: 182 FGYHWPPFRSVKHLHLHTIAPESEMGF 262
+ + + H HLH I + GF
Sbjct: 85 QNNYRAAGQLIDHFHLHLIPRHAHDGF 111
>UniRef50_A7QKZ8 Cluster: Chromosome chr8 scaffold_115, whole genome
shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome
chr8 scaffold_115, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 738
Score = 32.3 bits (70), Expect = 9.6
Identities = 22/87 (25%), Positives = 45/87 (51%), Gaps = 5/87 (5%)
Frame = +2
Query: 2 EVCVFRDIKPASRFHILTIPKRH-IEDVKSLTSADKELLNRMMSI----SRELLSKNNLS 166
+V V D+ P ++ H+L + + ++ + + +LL M ++ + + L ++ L
Sbjct: 560 DVVVLNDLYPKAQRHLLVLARSEGLDCLADVGGEHLQLLRTMHAVGLKWAEKFLCEDELL 619
Query: 167 IEDARFGYHWPPFRSVKHLHLHTIAPE 247
+ R GYH P S++ LHLH I+ +
Sbjct: 620 V--FRIGYHSAP--SMRQLHLHVISQD 642
>UniRef50_A3HAI2 Cluster: Histidine triad (HIT) protein; n=2;
Thermoprotei|Rep: Histidine triad (HIT) protein -
Caldivirga maquilingensis IC-167
Length = 151
Score = 32.3 bits (70), Expect = 9.6
Identities = 24/84 (28%), Positives = 42/84 (50%), Gaps = 5/84 (5%)
Frame = +2
Query: 2 EVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSK---NNLSIE 172
+V D P ++ HIL +PKRH D+ + E L ++M +++ L+++ N L +
Sbjct: 24 DVIAILDKYPINKGHILVMPKRHYRDIFEI---PPEALCKVMKVAK-LMARAVVNGLKAD 79
Query: 173 DARFGYHWPPF--RSVKHLHLHTI 238
R + P + V H H+H I
Sbjct: 80 GVRLIQNNGPSAGQVVFHFHVHVI 103
>UniRef50_O76463 Cluster: Nitrilase and fragile histidine triad
fusion protein NitFhit [Includes:
Bis(5'-adenosyl)-triphosphatase (EC 3.6.1.29)
(Diadenosine 5',5'''-P1,P3-triphosphate hydrolase)
(Dinucleosidetriphosphatase) (AP3A hydrolase) (AP3Aase);
Nitrilase homolog (EC 3.5.-.-)]; n=4; Bilateria|Rep:
Nitrilase and fragile histidine triad fusion protein
NitFhit [Includes: Bis(5'-adenosyl)-triphosphatase (EC
3.6.1.29) (Diadenosine 5',5'''-P1,P3-triphosphate
hydrolase) (Dinucleosidetriphosphatase) (AP3A hydrolase)
(AP3Aase); Nitrilase homolog (EC 3.5.-.-)] -
Caenorhabditis elegans
Length = 440
Score = 32.3 bits (70), Expect = 9.6
Identities = 27/102 (26%), Positives = 47/102 (46%), Gaps = 1/102 (0%)
Frame = +2
Query: 11 VFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSK-NNLSIEDARFG 187
VF ++KP + H+L PKR + + LT A+ L + + +L K +N++
Sbjct: 320 VFVNLKPVTDGHVLVSPKRVVPRLTDLTDAETADLFIVAKKVQAMLEKHHNVTSTTICVQ 379
Query: 188 YHWPPFRSVKHLHLHTIAPESEMGFIGRVIFKKNSYWFVSPE 313
++V H+H+H I P F I++K + PE
Sbjct: 380 DGKDAGQTVPHVHIH-ILPRRAGDFGDNEIYQKLASHDKEPE 420
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 575,712,637
Number of Sequences: 1657284
Number of extensions: 10757298
Number of successful extensions: 20064
Number of sequences better than 10.0: 130
Number of HSP's better than 10.0 without gapping: 19605
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 20035
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 45221970467
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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