Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmte22b22
(656 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC003547-1|AAH03547.1| 352|Homo sapiens sirtuin (silent mating ... 230 3e-60
BC003012-1|AAH03012.1| 352|Homo sapiens sirtuin (silent mating ... 230 3e-60
AY030277-1|AAK51133.1| 352|Homo sapiens SIRT2 protein. 230 3e-60
AJ505014-1|CAD43717.1| 369|Homo sapiens sirtuin type 2 protein. 230 3e-60
AF131800-1|AAD20046.1| 254|Homo sapiens Similar to rat 5E5 anti... 230 3e-60
AF095714-1|AAD45971.1| 352|Homo sapiens silencing information r... 230 3e-60
AF083107-1|AAD40850.2| 389|Homo sapiens sirtuin type 2 protein. 230 3e-60
BC001042-1|AAH01042.1| 399|Homo sapiens sirtuin (silent mating ... 198 2e-50
AF083108-1|AAD40851.1| 399|Homo sapiens sirtuin type 3 protein. 198 2e-50
DQ278604-1|ABB72675.1| 747|Homo sapiens sirtuin (silent mating ... 148 2e-35
BC012499-1|AAH12499.1| 555|Homo sapiens SIRT1 protein protein. 148 2e-35
AL133551-8|CAI16036.1| 747|Homo sapiens sirtuin (silent mating ... 148 2e-35
AF235040-1|AAG38486.1| 747|Homo sapiens SIR2alpha protein protein. 148 2e-35
AF083106-1|AAD40849.2| 747|Homo sapiens sirtuin type 1 protein. 148 2e-35
AF160214-1|AAF67015.1| 373|Homo sapiens silent information regu... 141 2e-33
AK131390-1|BAD18541.1| 127|Homo sapiens protein ( Homo sapiens ... 93 6e-19
BC109320-1|AAI09321.1| 314|Homo sapiens sirtuin (silent mating ... 64 6e-10
BC109319-1|AAI09320.1| 314|Homo sapiens sirtuin (silent mating ... 64 6e-10
AF083109-1|AAD40852.1| 314|Homo sapiens sirtuin type 4 protein. 64 6e-10
AC003982-1|AAB95634.1| 326|Homo sapiens WUGSC:H_166H1.1 protein. 59 1e-08
BC000126-1|AAH00126.1| 310|Homo sapiens sirtuin (silent mating ... 58 4e-08
AL441883-2|CAI19838.1| 310|Homo sapiens sirtuin (silent mating ... 58 4e-08
AL441883-1|CAI19837.1| 299|Homo sapiens sirtuin (silent mating ... 58 4e-08
AK000355-1|BAA91107.1| 299|Homo sapiens protein ( Homo sapiens ... 58 4e-08
AF083110-1|AAD40853.1| 310|Homo sapiens sirtuin type 5 protein. 58 4e-08
CR457200-1|CAG33481.1| 355|Homo sapiens SIRT6 protein. 57 5e-08
BC028220-1|AAH28220.1| 328|Homo sapiens SIRT6 protein protein. 57 5e-08
AK074810-1|BAC11222.1| 355|Homo sapiens protein ( Homo sapiens ... 57 5e-08
BC005026-1|AAH05026.1| 355|Homo sapiens sirtuin (silent mating ... 57 6e-08
AF233396-1|AAF43432.1| 355|Homo sapiens sir2-related protein ty... 57 6e-08
AC006930-1|AAD15478.1| 377|Homo sapiens R33423_1 protein. 57 6e-08
BC101793-1|AAI01794.1| 400|Homo sapiens sirtuin (silent mating ... 56 8e-08
BC101791-1|AAI01792.1| 400|Homo sapiens sirtuin (silent mating ... 56 8e-08
BC017305-1|AAH17305.1| 400|Homo sapiens sirtuin (silent mating ... 56 8e-08
AF233395-1|AAF43431.1| 400|Homo sapiens sir2-related protein ty... 56 8e-08
BC004218-1|AAH04218.1| 256|Homo sapiens SIRT6 protein protein. 46 2e-04
AK002027-1|BAA92044.1| 183|Homo sapiens protein ( Homo sapiens ... 39 0.018
BC000090-1|AAH00090.1| 191|Homo sapiens Unknown (protein for IM... 35 0.22
AK131484-1|BAD18629.1| 162|Homo sapiens protein ( Homo sapiens ... 32 1.6
X63071-1|CAA44793.1| 1179|Homo sapiens DBP-5 protein protein. 31 3.6
AK127947-1|BAC87202.1| 454|Homo sapiens protein ( Homo sapiens ... 31 3.6
AF380184-1|AAL34502.1| 2426|Homo sapiens SON DNA binding protein... 31 3.6
AF380181-1|AAL34499.1| 2325|Homo sapiens SON DNA binding protein... 31 3.6
AF380180-1|AAL34498.1| 2303|Homo sapiens SON DNA binding protein... 31 3.6
AF380179-1|AAL34497.1| 2140|Homo sapiens SON DNA binding protein... 31 3.6
AF139897-1|AAD50078.1| 344|Homo sapiens BASS1 protein. 31 3.6
AB028942-1|BAA82971.2| 2309|Homo sapiens KIAA1019 protein protein. 31 3.6
BC146792-1|AAI46793.1| 2624|Homo sapiens B double prime 1, subun... 31 4.8
AJ279120-1|CAC21448.1| 2187|Homo sapiens TFNR protein. 31 4.8
AJ238520-1|CAC04245.1| 2254|Homo sapiens putative transcription ... 31 4.8
AB051476-1|BAB21780.3| 2627|Homo sapiens KIAA1689 protein protein. 31 4.8
U57057-1|AAB47807.1| 525|Homo sapiens WD protein IR10 protein. 30 6.3
BC011690-1|AAH11690.1| 525|Homo sapiens coronin, actin binding ... 30 6.3
BC000010-1|AAH00010.1| 525|Homo sapiens coronin, actin binding ... 30 6.3
AL137073-9|CAI13893.1| 525|Homo sapiens coronin, actin binding ... 30 6.3
M36428-1|AAA36624.1| 483|Homo sapiens protein ( Human son3 prot... 30 8.3
AK128809-1|BAC87616.1| 404|Homo sapiens protein ( Homo sapiens ... 30 8.3
AK096209-1|BAC04725.1| 446|Homo sapiens protein ( Homo sapiens ... 30 8.3
AK091762-1|BAC03741.1| 446|Homo sapiens P86 mRNA. protein. 30 8.3
>BC003547-1|AAH03547.1| 352|Homo sapiens sirtuin (silent mating
type information regulation 2 homolog) 2 (S. cerevisiae)
protein.
Length = 352
Score = 230 bits (563), Expect = 3e-60
Identities = 104/154 (67%), Positives = 131/154 (85%)
Frame = +3
Query: 189 LFSPQDLEPAEPPEKVLDEVSLDGIVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETG 368
LFS Q L E++LDE++L+G+ R+++S+RC+++I L GAGISTSAGIPDFRSP TG
Sbjct: 7 LFS-QTLSLGSQKERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRSPSTG 65
Query: 369 LYHNLQKYELPQPQAIFEINFFRQNPKPFFTLAKELFPGSFKPTISHYFIRLLHEKGLLL 548
LY NL+KY LP P+AIFEI++F+++P+PFF LAKEL+PG FKPTI HYF+RLL +KGLLL
Sbjct: 66 LYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLL 125
Query: 549 RHYTQNIDTLERGAGIPEEKLVEAHGTFYTSHCL 650
R YTQNIDTLER AG+ +E LVEAHGTFYTSHC+
Sbjct: 126 RCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCV 159
>BC003012-1|AAH03012.1| 352|Homo sapiens sirtuin (silent mating
type information regulation 2 homolog) 2 (S. cerevisiae)
protein.
Length = 352
Score = 230 bits (563), Expect = 3e-60
Identities = 104/154 (67%), Positives = 131/154 (85%)
Frame = +3
Query: 189 LFSPQDLEPAEPPEKVLDEVSLDGIVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETG 368
LFS Q L E++LDE++L+G+ R+++S+RC+++I L GAGISTSAGIPDFRSP TG
Sbjct: 7 LFS-QTLSLGSQKERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRSPSTG 65
Query: 369 LYHNLQKYELPQPQAIFEINFFRQNPKPFFTLAKELFPGSFKPTISHYFIRLLHEKGLLL 548
LY NL+KY LP P+AIFEI++F+++P+PFF LAKEL+PG FKPTI HYF+RLL +KGLLL
Sbjct: 66 LYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLL 125
Query: 549 RHYTQNIDTLERGAGIPEEKLVEAHGTFYTSHCL 650
R YTQNIDTLER AG+ +E LVEAHGTFYTSHC+
Sbjct: 126 RCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCV 159
>AY030277-1|AAK51133.1| 352|Homo sapiens SIRT2 protein.
Length = 352
Score = 230 bits (563), Expect = 3e-60
Identities = 104/154 (67%), Positives = 131/154 (85%)
Frame = +3
Query: 189 LFSPQDLEPAEPPEKVLDEVSLDGIVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETG 368
LFS Q L E++LDE++L+G+ R+++S+RC+++I L GAGISTSAGIPDFRSP TG
Sbjct: 7 LFS-QTLSLGSQKERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRSPSTG 65
Query: 369 LYHNLQKYELPQPQAIFEINFFRQNPKPFFTLAKELFPGSFKPTISHYFIRLLHEKGLLL 548
LY NL+KY LP P+AIFEI++F+++P+PFF LAKEL+PG FKPTI HYF+RLL +KGLLL
Sbjct: 66 LYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLL 125
Query: 549 RHYTQNIDTLERGAGIPEEKLVEAHGTFYTSHCL 650
R YTQNIDTLER AG+ +E LVEAHGTFYTSHC+
Sbjct: 126 RCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCV 159
>AJ505014-1|CAD43717.1| 369|Homo sapiens sirtuin type 2 protein.
Length = 369
Score = 230 bits (563), Expect = 3e-60
Identities = 104/154 (67%), Positives = 131/154 (85%)
Frame = +3
Query: 189 LFSPQDLEPAEPPEKVLDEVSLDGIVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETG 368
LFS Q L E++LDE++L+G+ R+++S+RC+++I L GAGISTSAGIPDFRSP TG
Sbjct: 24 LFS-QTLSLGSQKERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRSPSTG 82
Query: 369 LYHNLQKYELPQPQAIFEINFFRQNPKPFFTLAKELFPGSFKPTISHYFIRLLHEKGLLL 548
LY NL+KY LP P+AIFEI++F+++P+PFF LAKEL+PG FKPTI HYF+RLL +KGLLL
Sbjct: 83 LYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLL 142
Query: 549 RHYTQNIDTLERGAGIPEEKLVEAHGTFYTSHCL 650
R YTQNIDTLER AG+ +E LVEAHGTFYTSHC+
Sbjct: 143 RCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCV 176
>AF131800-1|AAD20046.1| 254|Homo sapiens Similar to rat 5E5 antigen
protein.
Length = 254
Score = 230 bits (563), Expect = 3e-60
Identities = 104/154 (67%), Positives = 131/154 (85%)
Frame = +3
Query: 189 LFSPQDLEPAEPPEKVLDEVSLDGIVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETG 368
LFS Q L E++LDE++L+G+ R+++S+RC+++I L GAGISTSAGIPDFRSP TG
Sbjct: 27 LFS-QTLSLGSQKERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRSPSTG 85
Query: 369 LYHNLQKYELPQPQAIFEINFFRQNPKPFFTLAKELFPGSFKPTISHYFIRLLHEKGLLL 548
LY NL+KY LP P+AIFEI++F+++P+PFF LAKEL+PG FKPTI HYF+RLL +KGLLL
Sbjct: 86 LYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLL 145
Query: 549 RHYTQNIDTLERGAGIPEEKLVEAHGTFYTSHCL 650
R YTQNIDTLER AG+ +E LVEAHGTFYTSHC+
Sbjct: 146 RCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCV 179
>AF095714-1|AAD45971.1| 352|Homo sapiens silencing information
regulator 2-like protein protein.
Length = 352
Score = 230 bits (563), Expect = 3e-60
Identities = 104/154 (67%), Positives = 131/154 (85%)
Frame = +3
Query: 189 LFSPQDLEPAEPPEKVLDEVSLDGIVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETG 368
LFS Q L E++LDE++L+G+ R+++S+RC+++I L GAGISTSAGIPDFRSP TG
Sbjct: 7 LFS-QTLSLGSQKERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRSPSTG 65
Query: 369 LYHNLQKYELPQPQAIFEINFFRQNPKPFFTLAKELFPGSFKPTISHYFIRLLHEKGLLL 548
LY NL+KY LP P+AIFEI++F+++P+PFF LAKEL+PG FKPTI HYF+RLL +KGLLL
Sbjct: 66 LYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLL 125
Query: 549 RHYTQNIDTLERGAGIPEEKLVEAHGTFYTSHCL 650
R YTQNIDTLER AG+ +E LVEAHGTFYTSHC+
Sbjct: 126 RCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCV 159
>AF083107-1|AAD40850.2| 389|Homo sapiens sirtuin type 2 protein.
Length = 389
Score = 230 bits (563), Expect = 3e-60
Identities = 104/154 (67%), Positives = 131/154 (85%)
Frame = +3
Query: 189 LFSPQDLEPAEPPEKVLDEVSLDGIVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETG 368
LFS Q L E++LDE++L+G+ R+++S+RC+++I L GAGISTSAGIPDFRSP TG
Sbjct: 44 LFS-QTLSLGSQKERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRSPSTG 102
Query: 369 LYHNLQKYELPQPQAIFEINFFRQNPKPFFTLAKELFPGSFKPTISHYFIRLLHEKGLLL 548
LY NL+KY LP P+AIFEI++F+++P+PFF LAKEL+PG FKPTI HYF+RLL +KGLLL
Sbjct: 103 LYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLL 162
Query: 549 RHYTQNIDTLERGAGIPEEKLVEAHGTFYTSHCL 650
R YTQNIDTLER AG+ +E LVEAHGTFYTSHC+
Sbjct: 163 RCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCV 196
>BC001042-1|AAH01042.1| 399|Homo sapiens sirtuin (silent mating
type information regulation 2 homolog) 3 (S. cerevisiae)
protein.
Length = 399
Score = 198 bits (482), Expect = 2e-50
Identities = 86/138 (62%), Positives = 112/138 (81%)
Frame = +3
Query: 243 EVSLDGIVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFE 422
++SL + I++ C++++ + GAGIST +GIPDFRSP +GLY NLQ+Y+LP P+AIFE
Sbjct: 122 KLSLQDVAELIRARACQRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIFE 181
Query: 423 INFFRQNPKPFFTLAKELFPGSFKPTISHYFIRLLHEKGLLLRHYTQNIDTLERGAGIPE 602
+ FF NPKPFFTLAKEL+PG++KP ++HYF+RLLH+KGLLLR YTQNID LER +GIP
Sbjct: 182 LPFFFHNPKPFFTLAKELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPA 241
Query: 603 EKLVEAHGTFYTSHCLDC 656
KLVEAHGTF ++ C C
Sbjct: 242 SKLVEAHGTFASATCTVC 259
>AF083108-1|AAD40851.1| 399|Homo sapiens sirtuin type 3 protein.
Length = 399
Score = 198 bits (482), Expect = 2e-50
Identities = 86/138 (62%), Positives = 112/138 (81%)
Frame = +3
Query: 243 EVSLDGIVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFE 422
++SL + I++ C++++ + GAGIST +GIPDFRSP +GLY NLQ+Y+LP P+AIFE
Sbjct: 122 KLSLQDVAELIRARACQRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIFE 181
Query: 423 INFFRQNPKPFFTLAKELFPGSFKPTISHYFIRLLHEKGLLLRHYTQNIDTLERGAGIPE 602
+ FF NPKPFFTLAKEL+PG++KP ++HYF+RLLH+KGLLLR YTQNID LER +GIP
Sbjct: 182 LPFFFHNPKPFFTLAKELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPA 241
Query: 603 EKLVEAHGTFYTSHCLDC 656
KLVEAHGTF ++ C C
Sbjct: 242 SKLVEAHGTFASATCTVC 259
>DQ278604-1|ABB72675.1| 747|Homo sapiens sirtuin (silent mating
type information regulation 2 homolog) 1 (S. cerevisiae)
protein.
Length = 747
Score = 148 bits (358), Expect = 2e-35
Identities = 74/151 (49%), Positives = 109/151 (72%), Gaps = 4/151 (2%)
Frame = +3
Query: 216 AEPPE--KVLDEVSLDGIVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQK 389
+EPP+ K D +++ V+ ++ CKKII L+GAG+S S GIPDFRS + G+Y L
Sbjct: 229 SEPPKRKKRKDINTIEDAVKLLQE--CKKIIVLTGAGVSVSCGIPDFRSRD-GIYARLAV 285
Query: 390 Y--ELPQPQAIFEINFFRQNPKPFFTLAKELFPGSFKPTISHYFIRLLHEKGLLLRHYTQ 563
+LP PQA+F+I +FR++P+PFF AKE++PG F+P++ H FI L ++G LLR+YTQ
Sbjct: 286 DFPDLPDPQAMFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQ 345
Query: 564 NIDTLERGAGIPEEKLVEAHGTFYTSHCLDC 656
NIDTLE+ AGI +++++ HG+F T+ CL C
Sbjct: 346 NIDTLEQVAGI--QRIIQCHGSFATASCLIC 374
>BC012499-1|AAH12499.1| 555|Homo sapiens SIRT1 protein protein.
Length = 555
Score = 148 bits (358), Expect = 2e-35
Identities = 74/151 (49%), Positives = 109/151 (72%), Gaps = 4/151 (2%)
Frame = +3
Query: 216 AEPPE--KVLDEVSLDGIVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQK 389
+EPP+ K D +++ V+ ++ CKKII L+GAG+S S GIPDFRS + G+Y L
Sbjct: 37 SEPPKRKKRKDINTIEDAVKLLQE--CKKIIVLTGAGVSVSCGIPDFRSRD-GIYARLAV 93
Query: 390 Y--ELPQPQAIFEINFFRQNPKPFFTLAKELFPGSFKPTISHYFIRLLHEKGLLLRHYTQ 563
+LP PQA+F+I +FR++P+PFF AKE++PG F+P++ H FI L ++G LLR+YTQ
Sbjct: 94 DFPDLPDPQAMFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQ 153
Query: 564 NIDTLERGAGIPEEKLVEAHGTFYTSHCLDC 656
NIDTLE+ AGI +++++ HG+F T+ CL C
Sbjct: 154 NIDTLEQVAGI--QRIIQCHGSFATASCLIC 182
>AL133551-8|CAI16036.1| 747|Homo sapiens sirtuin (silent mating
type information regulation 2 homolog) 1 (S. cerevisiae)
protein.
Length = 747
Score = 148 bits (358), Expect = 2e-35
Identities = 74/151 (49%), Positives = 109/151 (72%), Gaps = 4/151 (2%)
Frame = +3
Query: 216 AEPPE--KVLDEVSLDGIVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQK 389
+EPP+ K D +++ V+ ++ CKKII L+GAG+S S GIPDFRS + G+Y L
Sbjct: 229 SEPPKRKKRKDINTIEDAVKLLQE--CKKIIVLTGAGVSVSCGIPDFRSRD-GIYARLAV 285
Query: 390 Y--ELPQPQAIFEINFFRQNPKPFFTLAKELFPGSFKPTISHYFIRLLHEKGLLLRHYTQ 563
+LP PQA+F+I +FR++P+PFF AKE++PG F+P++ H FI L ++G LLR+YTQ
Sbjct: 286 DFPDLPDPQAMFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQ 345
Query: 564 NIDTLERGAGIPEEKLVEAHGTFYTSHCLDC 656
NIDTLE+ AGI +++++ HG+F T+ CL C
Sbjct: 346 NIDTLEQVAGI--QRIIQCHGSFATASCLIC 374
>AF235040-1|AAG38486.1| 747|Homo sapiens SIR2alpha protein protein.
Length = 747
Score = 148 bits (358), Expect = 2e-35
Identities = 74/151 (49%), Positives = 109/151 (72%), Gaps = 4/151 (2%)
Frame = +3
Query: 216 AEPPE--KVLDEVSLDGIVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQK 389
+EPP+ K D +++ V+ ++ CKKII L+GAG+S S GIPDFRS + G+Y L
Sbjct: 229 SEPPKRKKRKDINTIEDAVKLLQE--CKKIIVLTGAGVSVSCGIPDFRSRD-GIYARLAV 285
Query: 390 Y--ELPQPQAIFEINFFRQNPKPFFTLAKELFPGSFKPTISHYFIRLLHEKGLLLRHYTQ 563
+LP PQA+F+I +FR++P+PFF AKE++PG F+P++ H FI L ++G LLR+YTQ
Sbjct: 286 DFPDLPDPQAMFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQ 345
Query: 564 NIDTLERGAGIPEEKLVEAHGTFYTSHCLDC 656
NIDTLE+ AGI +++++ HG+F T+ CL C
Sbjct: 346 NIDTLEQVAGI--QRIIQCHGSFATASCLIC 374
>AF083106-1|AAD40849.2| 747|Homo sapiens sirtuin type 1 protein.
Length = 747
Score = 148 bits (358), Expect = 2e-35
Identities = 74/151 (49%), Positives = 109/151 (72%), Gaps = 4/151 (2%)
Frame = +3
Query: 216 AEPPE--KVLDEVSLDGIVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQK 389
+EPP+ K D +++ V+ ++ CKKII L+GAG+S S GIPDFRS + G+Y L
Sbjct: 229 SEPPKRKKRKDINTIEDAVKLLQE--CKKIIVLTGAGVSVSCGIPDFRSRD-GIYARLAV 285
Query: 390 Y--ELPQPQAIFEINFFRQNPKPFFTLAKELFPGSFKPTISHYFIRLLHEKGLLLRHYTQ 563
+LP PQA+F+I +FR++P+PFF AKE++PG F+P++ H FI L ++G LLR+YTQ
Sbjct: 286 DFPDLPDPQAMFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQ 345
Query: 564 NIDTLERGAGIPEEKLVEAHGTFYTSHCLDC 656
NIDTLE+ AGI +++++ HG+F T+ CL C
Sbjct: 346 NIDTLEQVAGI--QRIIQCHGSFATASCLIC 374
>AF160214-1|AAF67015.1| 373|Homo sapiens silent information
regulator 2 homolog protein.
Length = 373
Score = 141 bits (342), Expect = 2e-33
Identities = 62/102 (60%), Positives = 85/102 (83%)
Frame = +3
Query: 189 LFSPQDLEPAEPPEKVLDEVSLDGIVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETG 368
LFS Q L E++LDE++L+G+ R+++S+RC+++I L GAGISTSAGIPDFRSP TG
Sbjct: 28 LFS-QTLSLGSQKERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRSPSTG 86
Query: 369 LYHNLQKYELPQPQAIFEINFFRQNPKPFFTLAKELFPGSFK 494
LY NL+KY LP P+AIFEI++F+++P+PFF LAKEL+PG F+
Sbjct: 87 LYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFQ 128
>AK131390-1|BAD18541.1| 127|Homo sapiens protein ( Homo sapiens
cDNA FLJ16468 fis, clone BRHIP3008314, moderately
similar to Homo sapiens sirtuin 2 (SIRT2). ).
Length = 127
Score = 93.5 bits (222), Expect = 6e-19
Identities = 42/55 (76%), Positives = 48/55 (87%)
Frame = +3
Query: 486 SFKPTISHYFIRLLHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHGTFYTSHCL 650
S +PTI HYF+RLL +KGLLLR YTQNIDTLER AG+ +E LVEAHGTFYTSHC+
Sbjct: 19 SLQPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCV 73
>BC109320-1|AAI09321.1| 314|Homo sapiens sirtuin (silent mating
type information regulation 2 homolog) 4 (S. cerevisiae)
protein.
Length = 314
Score = 63.7 bits (148), Expect = 6e-10
Identities = 45/148 (30%), Positives = 69/148 (46%)
Frame = +3
Query: 213 PAEPPEKVLDEVSLDGIVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKY 392
PA PP LD + + R+I K+++ ++GAGIST +GIPD+RS + GLY +
Sbjct: 34 PASPP---LDPEKVKELQRFITLS--KRLLVMTGAGISTESGIPDYRSEKVGLYARTDRR 88
Query: 393 ELPQPQAIFEINFFRQNPKPFFTLAKELFPGSFKPTISHYFIRLLHEKGLLLRHYTQNID 572
+ + ++ F + S +P +H+ + + G L TQN+D
Sbjct: 89 PIQHGDFVRSAPIRQRYWARNFVGWPQF--SSHQPNPAHWALSTWEKLGKLYWLVTQNVD 146
Query: 573 TLERGAGIPEEKLVEAHGTFYTSHCLDC 656
L AG +L E HG CLDC
Sbjct: 147 ALHTKAG--SRRLTELHGCMDRVLCLDC 172
>BC109319-1|AAI09320.1| 314|Homo sapiens sirtuin (silent mating
type information regulation 2 homolog) 4 (S. cerevisiae)
protein.
Length = 314
Score = 63.7 bits (148), Expect = 6e-10
Identities = 45/148 (30%), Positives = 69/148 (46%)
Frame = +3
Query: 213 PAEPPEKVLDEVSLDGIVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKY 392
PA PP LD + + R+I K+++ ++GAGIST +GIPD+RS + GLY +
Sbjct: 34 PASPP---LDPEKVKELQRFITLS--KRLLVMTGAGISTESGIPDYRSEKVGLYARTDRR 88
Query: 393 ELPQPQAIFEINFFRQNPKPFFTLAKELFPGSFKPTISHYFIRLLHEKGLLLRHYTQNID 572
+ + ++ F + S +P +H+ + + G L TQN+D
Sbjct: 89 PIQHGDFVRSAPIRQRYWARNFVGWPQF--SSHQPNPAHWALSTWEKLGKLYWLVTQNVD 146
Query: 573 TLERGAGIPEEKLVEAHGTFYTSHCLDC 656
L AG +L E HG CLDC
Sbjct: 147 ALHTKAG--SRRLTELHGCMDRVLCLDC 172
>AF083109-1|AAD40852.1| 314|Homo sapiens sirtuin type 4 protein.
Length = 314
Score = 63.7 bits (148), Expect = 6e-10
Identities = 45/148 (30%), Positives = 69/148 (46%)
Frame = +3
Query: 213 PAEPPEKVLDEVSLDGIVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKY 392
PA PP LD + + R+I K+++ ++GAGIST +GIPD+RS + GLY +
Sbjct: 34 PASPP---LDPEKVKELQRFITLS--KRLLVMTGAGISTESGIPDYRSEKVGLYARTDRR 88
Query: 393 ELPQPQAIFEINFFRQNPKPFFTLAKELFPGSFKPTISHYFIRLLHEKGLLLRHYTQNID 572
+ + ++ F + S +P +H+ + + G L TQN+D
Sbjct: 89 PIQHGDFVRSAPIRQRYWARNFVGWPQF--SSHQPNPAHWALSTWEKLGKLYWLVTQNVD 146
Query: 573 TLERGAGIPEEKLVEAHGTFYTSHCLDC 656
L AG +L E HG CLDC
Sbjct: 147 ALHTKAG--SRRLTELHGCMDRVLCLDC 172
>AC003982-1|AAB95634.1| 326|Homo sapiens WUGSC:H_166H1.1 protein.
Length = 326
Score = 59.3 bits (137), Expect = 1e-08
Identities = 42/145 (28%), Positives = 68/145 (46%)
Frame = +3
Query: 213 PAEPPEKVLDEVSLDGIVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKY 392
PA PP LD + + R+I K+++ ++GAGIST +GIPD+RS + GLY +
Sbjct: 34 PASPP---LDPEKVKELQRFITLS--KRLLVMTGAGISTESGIPDYRSEKVGLYARTDRR 88
Query: 393 ELPQPQAIFEINFFRQNPKPFFTLAKELFPGSFKPTISHYFIRLLHEKGLLLRHYTQNID 572
+ + ++ F + S +P +H+ + + G L TQN+D
Sbjct: 89 PIQHGDFVRSAPIRQRYWARNFVGWPQF--SSHQPNPAHWALSTWEKLGKLYWLVTQNVD 146
Query: 573 TLERGAGIPEEKLVEAHGTFYTSHC 647
L AG +L E HG ++C
Sbjct: 147 ALHTKAG--SRRLTELHGCMDRAYC 169
>BC000126-1|AAH00126.1| 310|Homo sapiens sirtuin (silent mating
type information regulation 2 homolog) 5 (S. cerevisiae)
protein.
Length = 310
Score = 57.6 bits (133), Expect = 4e-08
Identities = 43/131 (32%), Positives = 63/131 (48%), Gaps = 7/131 (5%)
Frame = +3
Query: 285 RCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPK---PF 455
+ K I+ +SGAG+S +G+P FR G + Q +L P A F NP F
Sbjct: 49 KAKHIVIISGAGVSAESGVPTFRG-AGGYWRKWQAQDLATPLA------FAHNPSRVWEF 101
Query: 456 FTLAKELFPGSFKPTISHYFI----RLLHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAH 623
+ +E+ GS +P H I L ++G + TQNID L R AG + L+E H
Sbjct: 102 YHYRREVM-GSKEPNAGHRAIAECETRLGKQGRRVVVITQNIDELHRKAG--TKNLLEIH 158
Query: 624 GTFYTSHCLDC 656
G+ + + C C
Sbjct: 159 GSLFKTRCTSC 169
>AL441883-2|CAI19838.1| 310|Homo sapiens sirtuin (silent mating
type information regulation 2 homolog) 5 (S. cerevisiae)
protein.
Length = 310
Score = 57.6 bits (133), Expect = 4e-08
Identities = 43/131 (32%), Positives = 63/131 (48%), Gaps = 7/131 (5%)
Frame = +3
Query: 285 RCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPK---PF 455
+ K I+ +SGAG+S +G+P FR G + Q +L P A F NP F
Sbjct: 49 KAKHIVIISGAGVSAESGVPTFRG-AGGYWRKWQAQDLATPLA------FAHNPSRVWEF 101
Query: 456 FTLAKELFPGSFKPTISHYFI----RLLHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAH 623
+ +E+ GS +P H I L ++G + TQNID L R AG + L+E H
Sbjct: 102 YHYRREVM-GSKEPNAGHRAIAECETRLGKQGRRVVVITQNIDELHRKAG--TKNLLEIH 158
Query: 624 GTFYTSHCLDC 656
G+ + + C C
Sbjct: 159 GSLFKTRCTSC 169
>AL441883-1|CAI19837.1| 299|Homo sapiens sirtuin (silent mating
type information regulation 2 homolog) 5 (S. cerevisiae)
protein.
Length = 299
Score = 57.6 bits (133), Expect = 4e-08
Identities = 43/131 (32%), Positives = 63/131 (48%), Gaps = 7/131 (5%)
Frame = +3
Query: 285 RCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPK---PF 455
+ K I+ +SGAG+S +G+P FR G + Q +L P A F NP F
Sbjct: 49 KAKHIVIISGAGVSAESGVPTFRG-AGGYWRKWQAQDLATPLA------FAHNPSRVWEF 101
Query: 456 FTLAKELFPGSFKPTISHYFI----RLLHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAH 623
+ +E+ GS +P H I L ++G + TQNID L R AG + L+E H
Sbjct: 102 YHYRREVM-GSKEPNAGHRAIAECETRLGKQGRRVVVITQNIDELHRKAG--TKNLLEIH 158
Query: 624 GTFYTSHCLDC 656
G+ + + C C
Sbjct: 159 GSLFKTRCTSC 169
>AK000355-1|BAA91107.1| 299|Homo sapiens protein ( Homo sapiens
cDNA FLJ20348 fis, clone HEP13915. ).
Length = 299
Score = 57.6 bits (133), Expect = 4e-08
Identities = 43/131 (32%), Positives = 63/131 (48%), Gaps = 7/131 (5%)
Frame = +3
Query: 285 RCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPK---PF 455
+ K I+ +SGAG+S +G+P FR G + Q +L P A F NP F
Sbjct: 49 KAKHIVIISGAGVSAESGVPTFRG-AGGYWRKWQAQDLATPLA------FAHNPSRVWEF 101
Query: 456 FTLAKELFPGSFKPTISHYFI----RLLHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAH 623
+ +E+ GS +P H I L ++G + TQNID L R AG + L+E H
Sbjct: 102 YHYRREVM-GSKEPNAGHRAIAECETRLGKQGRRVVVITQNIDELHRKAG--TKNLLEIH 158
Query: 624 GTFYTSHCLDC 656
G+ + + C C
Sbjct: 159 GSLFKTRCTSC 169
>AF083110-1|AAD40853.1| 310|Homo sapiens sirtuin type 5 protein.
Length = 310
Score = 57.6 bits (133), Expect = 4e-08
Identities = 43/131 (32%), Positives = 63/131 (48%), Gaps = 7/131 (5%)
Frame = +3
Query: 285 RCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPK---PF 455
+ K I+ +SGAG+S +G+P FR G + Q +L P A F NP F
Sbjct: 49 KAKHIVIISGAGVSAESGVPTFRG-AGGYWRKWQAQDLATPLA------FAHNPSRVWEF 101
Query: 456 FTLAKELFPGSFKPTISHYFI----RLLHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAH 623
+ +E+ GS +P H I L ++G + TQNID L R AG + L+E H
Sbjct: 102 YHYRREVM-GSKEPNAGHRAIAECETRLGKQGRRVVVITQNIDELHRKAG--TKNLLEIH 158
Query: 624 GTFYTSHCLDC 656
G+ + + C C
Sbjct: 159 GSLFKTRCTSC 169
>CR457200-1|CAG33481.1| 355|Homo sapiens SIRT6 protein.
Length = 355
Score = 57.2 bits (132), Expect = 5e-08
Identities = 46/147 (31%), Positives = 69/147 (46%), Gaps = 1/147 (0%)
Frame = +3
Query: 219 EPPEKVLDEV-SLDGIVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYE 395
+PPE++ +V L +VR S ++ +GAGIST++GIPDFR P G++ ++
Sbjct: 25 DPPEELERKVWELARLVRQSSS-----VVFHTGAGISTASGIPDFRGPH-GVWTMEERGL 78
Query: 396 LPQPQAIFEINFFRQNPKPFFTLAKELFPGSFKPTISHYFIRLLHEKGLLLRHYTQNIDT 575
P+ FE S +PT +H + L GLL +QN+D
Sbjct: 79 APKFDTTFE---------------------SARPTQTHMALVQLERVGLLRFLVSQNVDG 117
Query: 576 LERGAGIPEEKLVEAHGTFYTSHCLDC 656
L +G P +KL E HG + C C
Sbjct: 118 LHVRSGFPRDKLAELHGNMFVEECAKC 144
>BC028220-1|AAH28220.1| 328|Homo sapiens SIRT6 protein protein.
Length = 328
Score = 57.2 bits (132), Expect = 5e-08
Identities = 44/146 (30%), Positives = 68/146 (46%)
Frame = +3
Query: 219 EPPEKVLDEVSLDGIVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYEL 398
+PPE++ +V + W S+ ++ +GAGIST++GIPDFR P G++ ++
Sbjct: 25 DPPEELERKVWELARLVWQSSN----VVFHTGAGISTASGIPDFRGPH-GVWTMEERGLA 79
Query: 399 PQPQAIFEINFFRQNPKPFFTLAKELFPGSFKPTISHYFIRLLHEKGLLLRHYTQNIDTL 578
P+ FE S +PT +H + L GLL +QN+D L
Sbjct: 80 PKFDTTFE---------------------SARPTQTHMALVQLERVGLLRFLVSQNVDGL 118
Query: 579 ERGAGIPEEKLVEAHGTFYTSHCLDC 656
+G P +KL E HG + C C
Sbjct: 119 HVRSGFPRDKLAELHGNMFVEECAKC 144
>AK074810-1|BAC11222.1| 355|Homo sapiens protein ( Homo sapiens
cDNA FLJ90329 fis, clone NT2RP2001948, weakly similar to
HST2 PROTEIN. ).
Length = 355
Score = 57.2 bits (132), Expect = 5e-08
Identities = 44/146 (30%), Positives = 68/146 (46%)
Frame = +3
Query: 219 EPPEKVLDEVSLDGIVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYEL 398
+PPE++ +V + W S+ ++ +GAGIST++GIPDFR P G++ ++
Sbjct: 25 DPPEELERKVWELARLVWQSSN----VVFHTGAGISTASGIPDFRGPH-GVWTMEERGLA 79
Query: 399 PQPQAIFEINFFRQNPKPFFTLAKELFPGSFKPTISHYFIRLLHEKGLLLRHYTQNIDTL 578
P+ FE S +PT +H + L GLL +QN+D L
Sbjct: 80 PKFDTTFE---------------------SARPTQTHMALVQLERVGLLRFLVSQNVDGL 118
Query: 579 ERGAGIPEEKLVEAHGTFYTSHCLDC 656
+G P +KL E HG + C C
Sbjct: 119 HVRSGFPRDKLAELHGNMFVEECAKC 144
>BC005026-1|AAH05026.1| 355|Homo sapiens sirtuin (silent mating
type information regulation 2 homolog) 6 (S. cerevisiae)
protein.
Length = 355
Score = 56.8 bits (131), Expect = 6e-08
Identities = 44/146 (30%), Positives = 67/146 (45%)
Frame = +3
Query: 219 EPPEKVLDEVSLDGIVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYEL 398
+PPE++ +V + W S ++ +GAGIST++GIPDFR P G++ ++
Sbjct: 25 DPPEELERKVWELARLVWQSSS----VVFHTGAGISTASGIPDFRGPH-GVWTMEERGLA 79
Query: 399 PQPQAIFEINFFRQNPKPFFTLAKELFPGSFKPTISHYFIRLLHEKGLLLRHYTQNIDTL 578
P+ FE S +PT +H + L GLL +QN+D L
Sbjct: 80 PKFDTTFE---------------------SARPTQTHMALVQLERVGLLRFLVSQNVDGL 118
Query: 579 ERGAGIPEEKLVEAHGTFYTSHCLDC 656
+G P +KL E HG + C C
Sbjct: 119 HVRSGFPRDKLAELHGNMFVEECAKC 144
>AF233396-1|AAF43432.1| 355|Homo sapiens sir2-related protein type
6 protein.
Length = 355
Score = 56.8 bits (131), Expect = 6e-08
Identities = 44/146 (30%), Positives = 67/146 (45%)
Frame = +3
Query: 219 EPPEKVLDEVSLDGIVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYEL 398
+PPE++ +V + W S ++ +GAGIST++GIPDFR P G++ ++
Sbjct: 25 DPPEELERKVWELARLVWQSSS----VVFHTGAGISTASGIPDFRGPH-GVWTMEERGLA 79
Query: 399 PQPQAIFEINFFRQNPKPFFTLAKELFPGSFKPTISHYFIRLLHEKGLLLRHYTQNIDTL 578
P+ FE S +PT +H + L GLL +QN+D L
Sbjct: 80 PKFDTTFE---------------------SARPTQTHMALVQLERVGLLRFLVSQNVDGL 118
Query: 579 ERGAGIPEEKLVEAHGTFYTSHCLDC 656
+G P +KL E HG + C C
Sbjct: 119 HVRSGFPRDKLAELHGNMFVEECAKC 144
>AC006930-1|AAD15478.1| 377|Homo sapiens R33423_1 protein.
Length = 377
Score = 56.8 bits (131), Expect = 6e-08
Identities = 44/146 (30%), Positives = 67/146 (45%)
Frame = +3
Query: 219 EPPEKVLDEVSLDGIVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYEL 398
+PPE++ +V + W S ++ +GAGIST++GIPDFR P G++ ++
Sbjct: 25 DPPEELERKVWELARLVWQSSS----VVFHTGAGISTASGIPDFRGPH-GVWTMEERGLA 79
Query: 399 PQPQAIFEINFFRQNPKPFFTLAKELFPGSFKPTISHYFIRLLHEKGLLLRHYTQNIDTL 578
P+ FE S +PT +H + L GLL +QN+D L
Sbjct: 80 PKFDTTFE---------------------SARPTQTHMALVQLERVGLLRFLVSQNVDGL 118
Query: 579 ERGAGIPEEKLVEAHGTFYTSHCLDC 656
+G P +KL E HG + C C
Sbjct: 119 HVRSGFPRDKLAELHGNMFVEECAKC 144
>BC101793-1|AAI01794.1| 400|Homo sapiens sirtuin (silent mating
type information regulation 2 homolog) 7 (S. cerevisiae)
protein.
Length = 400
Score = 56.4 bits (130), Expect = 8e-08
Identities = 46/146 (31%), Positives = 66/146 (45%), Gaps = 3/146 (2%)
Frame = +3
Query: 228 EKVLDEVS-LDGIVRWIKSD--RCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYEL 398
E+V D+ L G VR + S K ++ +GAGIST+A IPD+R P G++ LQK
Sbjct: 76 EEVCDDPEELRGKVRELASAVRNAKYLVVYTGAGISTAASIPDYRGPN-GVWTLLQKGRS 134
Query: 399 PQPQAIFEINFFRQNPKPFFTLAKELFPGSFKPTISHYFIRLLHEKGLLLRHYTQNIDTL 578
+ E +PT++H I LHE+ L+ +QN D L
Sbjct: 135 VSAADLSEA----------------------EPTLTHMSITRLHEQKLVQHVVSQNCDGL 172
Query: 579 ERGAGIPEEKLVEAHGTFYTSHCLDC 656
+G+P + E HG Y C C
Sbjct: 173 HLRSGLPRTAISELHGNMYIEVCTSC 198
>BC101791-1|AAI01792.1| 400|Homo sapiens sirtuin (silent mating
type information regulation 2 homolog) 7 (S. cerevisiae)
protein.
Length = 400
Score = 56.4 bits (130), Expect = 8e-08
Identities = 46/146 (31%), Positives = 66/146 (45%), Gaps = 3/146 (2%)
Frame = +3
Query: 228 EKVLDEVS-LDGIVRWIKSD--RCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYEL 398
E+V D+ L G VR + S K ++ +GAGIST+A IPD+R P G++ LQK
Sbjct: 76 EEVCDDPEELRGKVRELASAVRNAKYLVVYTGAGISTAASIPDYRGPN-GVWTLLQKGRS 134
Query: 399 PQPQAIFEINFFRQNPKPFFTLAKELFPGSFKPTISHYFIRLLHEKGLLLRHYTQNIDTL 578
+ E +PT++H I LHE+ L+ +QN D L
Sbjct: 135 VSAADLSEA----------------------EPTLTHMSITRLHEQKLVQHVVSQNCDGL 172
Query: 579 ERGAGIPEEKLVEAHGTFYTSHCLDC 656
+G+P + E HG Y C C
Sbjct: 173 HLRSGLPRTAISELHGNMYIEVCTSC 198
>BC017305-1|AAH17305.1| 400|Homo sapiens sirtuin (silent mating
type information regulation 2 homolog) 7 (S. cerevisiae)
protein.
Length = 400
Score = 56.4 bits (130), Expect = 8e-08
Identities = 46/146 (31%), Positives = 66/146 (45%), Gaps = 3/146 (2%)
Frame = +3
Query: 228 EKVLDEVS-LDGIVRWIKSD--RCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYEL 398
E+V D+ L G VR + S K ++ +GAGIST+A IPD+R P G++ LQK
Sbjct: 76 EEVCDDPEELRGKVRELASAVRNAKYLVVYTGAGISTAASIPDYRGPN-GVWTLLQKGRS 134
Query: 399 PQPQAIFEINFFRQNPKPFFTLAKELFPGSFKPTISHYFIRLLHEKGLLLRHYTQNIDTL 578
+ E +PT++H I LHE+ L+ +QN D L
Sbjct: 135 VSAADLSEA----------------------EPTLTHMSITRLHEQKLVQHVVSQNCDGL 172
Query: 579 ERGAGIPEEKLVEAHGTFYTSHCLDC 656
+G+P + E HG Y C C
Sbjct: 173 HLRSGLPRTAISELHGNMYIEVCTSC 198
>AF233395-1|AAF43431.1| 400|Homo sapiens sir2-related protein type
7 protein.
Length = 400
Score = 56.4 bits (130), Expect = 8e-08
Identities = 46/146 (31%), Positives = 66/146 (45%), Gaps = 3/146 (2%)
Frame = +3
Query: 228 EKVLDEVS-LDGIVRWIKSD--RCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYEL 398
E+V D+ L G VR + S K ++ +GAGIST+A IPD+R P G++ LQK
Sbjct: 76 EEVCDDPEELRGKVRELASAVRNAKYLVVYTGAGISTAASIPDYRGPN-GVWTLLQKGRS 134
Query: 399 PQPQAIFEINFFRQNPKPFFTLAKELFPGSFKPTISHYFIRLLHEKGLLLRHYTQNIDTL 578
+ E +PT++H I LHE+ L+ +QN D L
Sbjct: 135 VSAADLSEA----------------------EPTLTHMSITRLHEQKLVQHVVSQNCDGL 172
Query: 579 ERGAGIPEEKLVEAHGTFYTSHCLDC 656
+G+P + E HG Y C C
Sbjct: 173 HLRSGLPRTAISELHGNMYIEVCTSC 198
>BC004218-1|AAH04218.1| 256|Homo sapiens SIRT6 protein protein.
Length = 256
Score = 45.6 bits (103), Expect = 2e-04
Identities = 21/57 (36%), Positives = 29/57 (50%)
Frame = +3
Query: 486 SFKPTISHYFIRLLHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHGTFYTSHCLDC 656
S +PT +H + L GLL +QN+D L +G P +KL E HG + C C
Sbjct: 16 SARPTQTHMALVQLERVGLLRFLVSQNVDGLHVRSGFPRDKLAELHGNMFVEECAKC 72
>AK002027-1|BAA92044.1| 183|Homo sapiens protein ( Homo sapiens
cDNA FLJ11165 fis, clone PLACE1007238. ).
Length = 183
Score = 38.7 bits (86), Expect = 0.018
Identities = 25/57 (43%), Positives = 35/57 (61%), Gaps = 3/57 (5%)
Frame = +3
Query: 228 EKVLDEVS-LDGIVRWIKSD--RCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQK 389
E+V D+ L G VR + S K ++ +GAGIST+A IPD+R P G++ LQK
Sbjct: 76 EEVCDDPEELRGKVRELASAVRNAKYLVVYTGAGISTAASIPDYRGP-NGVWTLLQK 131
>BC000090-1|AAH00090.1| 191|Homo sapiens Unknown (protein for
IMAGE:3504121) protein.
Length = 191
Score = 35.1 bits (77), Expect = 0.22
Identities = 20/55 (36%), Positives = 33/55 (60%)
Frame = +3
Query: 219 EPPEKVLDEVSLDGIVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNL 383
+PPE++ +V + W S+ ++ +GAGIST++GIPDFR L+ N+
Sbjct: 29 DPPEELERKVWELARLVWQSSN----VVFHTGAGISTASGIPDFRDKLAELHGNM 79
>AK131484-1|BAD18629.1| 162|Homo sapiens protein ( Homo sapiens
cDNA FLJ16662 fis, clone TESTI4046240, highly similar
to Homo sapiens sirtuin 7 (SIRT7). ).
Length = 162
Score = 32.3 bits (70), Expect = 1.6
Identities = 15/40 (37%), Positives = 21/40 (52%)
Frame = +3
Query: 516 IRLLHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHGTFY 635
I LHE+ L+ +QN D L +G+P + E HG Y
Sbjct: 3 ITRLHEQKLVQHVVSQNCDGLHLRSGLPRTAISELHGNMY 42
>X63071-1|CAA44793.1| 1179|Homo sapiens DBP-5 protein protein.
Length = 1179
Score = 31.1 bits (67), Expect = 3.6
Identities = 32/113 (28%), Positives = 49/113 (43%), Gaps = 7/113 (6%)
Frame = +3
Query: 171 LALKLGLFSPQDLEPAEPP--EKVLDEVSLDGIVRWIKSDRCKKIITLSGAG--ISTSAG 338
+ K G+ P +L+PA PP E+ + + S + + +++CK+I I
Sbjct: 925 MCAKAGVPLPPNLKPAPPPTIEEKVAKKSGGATIEEL-TEKCKQIAQSKEDDDVIVNKPH 983
Query: 339 IPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKP---FFTLAKELFPGS 488
+ D E YH+ K P+P F +N P P TL KE FP S
Sbjct: 984 VSDEEEEEPPFYHHPFKLSEPKP-IFFNLNIAAAKPTPPKSQVTLTKE-FPVS 1034
>AK127947-1|BAC87202.1| 454|Homo sapiens protein ( Homo sapiens
cDNA FLJ46057 fis, clone T1ESE2000609, highly similar
to SON protein. ).
Length = 454
Score = 31.1 bits (67), Expect = 3.6
Identities = 32/113 (28%), Positives = 49/113 (43%), Gaps = 7/113 (6%)
Frame = +3
Query: 171 LALKLGLFSPQDLEPAEPP--EKVLDEVSLDGIVRWIKSDRCKKIITLSGAG--ISTSAG 338
+ K G+ P +L+PA PP E+ + + S + + +++CK+I I
Sbjct: 97 MCAKAGVPLPPNLKPAPPPTIEEKVAKKSGGATIEEL-TEKCKQIAQSKEDDDVIVNKPH 155
Query: 339 IPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKP---FFTLAKELFPGS 488
+ D E YH+ K P+P F +N P P TL KE FP S
Sbjct: 156 VSDEEEEEPPFYHHPFKLSEPKP-IFFNLNIAAAKPTPPKSQVTLTKE-FPVS 206
>AF380184-1|AAL34502.1| 2426|Homo sapiens SON DNA binding protein
isoform F protein.
Length = 2426
Score = 31.1 bits (67), Expect = 3.6
Identities = 32/113 (28%), Positives = 49/113 (43%), Gaps = 7/113 (6%)
Frame = +3
Query: 171 LALKLGLFSPQDLEPAEPP--EKVLDEVSLDGIVRWIKSDRCKKIITLSGAG--ISTSAG 338
+ K G+ P +L+PA PP E+ + + S + + +++CK+I I
Sbjct: 2069 MCAKAGVPLPPNLKPAPPPTIEEKVAKKSGGATIEEL-TEKCKQIAQSKEDDDVIVNKPH 2127
Query: 339 IPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKP---FFTLAKELFPGS 488
+ D E YH+ K P+P F +N P P TL KE FP S
Sbjct: 2128 VSDEEEEEPPFYHHPFKLSEPKP-IFFNLNIAAAKPTPPKSQVTLTKE-FPVS 2178
>AF380181-1|AAL34499.1| 2325|Homo sapiens SON DNA binding protein
isoform C protein.
Length = 2325
Score = 31.1 bits (67), Expect = 3.6
Identities = 32/113 (28%), Positives = 49/113 (43%), Gaps = 7/113 (6%)
Frame = +3
Query: 171 LALKLGLFSPQDLEPAEPP--EKVLDEVSLDGIVRWIKSDRCKKIITLSGAG--ISTSAG 338
+ K G+ P +L+PA PP E+ + + S + + +++CK+I I
Sbjct: 2069 MCAKAGVPLPPNLKPAPPPTIEEKVAKKSGGATIEEL-TEKCKQIAQSKEDDDVIVNKPH 2127
Query: 339 IPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKP---FFTLAKELFPGS 488
+ D E YH+ K P+P F +N P P TL KE FP S
Sbjct: 2128 VSDEEEEEPPFYHHPFKLSEPKP-IFFNLNIAAAKPTPPKSQVTLTKE-FPVS 2178
>AF380180-1|AAL34498.1| 2303|Homo sapiens SON DNA binding protein
isoform B protein.
Length = 2303
Score = 31.1 bits (67), Expect = 3.6
Identities = 32/113 (28%), Positives = 49/113 (43%), Gaps = 7/113 (6%)
Frame = +3
Query: 171 LALKLGLFSPQDLEPAEPP--EKVLDEVSLDGIVRWIKSDRCKKIITLSGAG--ISTSAG 338
+ K G+ P +L+PA PP E+ + + S + + +++CK+I I
Sbjct: 2069 MCAKAGVPLPPNLKPAPPPTIEEKVAKKSGGATIEEL-TEKCKQIAQSKEDDDVIVNKPH 2127
Query: 339 IPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKP---FFTLAKELFPGS 488
+ D E YH+ K P+P F +N P P TL KE FP S
Sbjct: 2128 VSDEEEEEPPFYHHPFKLSEPKP-IFFNLNIAAAKPTPPKSQVTLTKE-FPVS 2178
>AF380179-1|AAL34497.1| 2140|Homo sapiens SON DNA binding protein
isoform A protein.
Length = 2140
Score = 31.1 bits (67), Expect = 3.6
Identities = 32/113 (28%), Positives = 49/113 (43%), Gaps = 7/113 (6%)
Frame = +3
Query: 171 LALKLGLFSPQDLEPAEPP--EKVLDEVSLDGIVRWIKSDRCKKIITLSGAG--ISTSAG 338
+ K G+ P +L+PA PP E+ + + S + + +++CK+I I
Sbjct: 1750 MCAKAGVPLPPNLKPAPPPTIEEKVAKKSGGATIEEL-TEKCKQIAQSKEDDDVIVNKPH 1808
Query: 339 IPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKP---FFTLAKELFPGS 488
+ D E YH+ K P+P F +N P P TL KE FP S
Sbjct: 1809 VSDEEEEEPPFYHHPFKLSEPKP-IFFNLNIAAAKPTPPKSQVTLTKE-FPVS 1859
>AF139897-1|AAD50078.1| 344|Homo sapiens BASS1 protein.
Length = 344
Score = 31.1 bits (67), Expect = 3.6
Identities = 32/113 (28%), Positives = 49/113 (43%), Gaps = 7/113 (6%)
Frame = +3
Query: 171 LALKLGLFSPQDLEPAEPP--EKVLDEVSLDGIVRWIKSDRCKKIITLSGAG--ISTSAG 338
+ K G+ P +L+PA PP E+ + + S + + +++CK+I I
Sbjct: 131 MCAKAGVPLPPNLKPAPPPTIEEKVAKKSGGATIEEL-TEKCKQIAQSKEDDDVIVNKPH 189
Query: 339 IPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKP---FFTLAKELFPGS 488
+ D E YH+ K P+P F +N P P TL KE FP S
Sbjct: 190 VSDEEEEEPPFYHHPFKLSEPKP-IFFNLNIAAAKPTPPKSQVTLTKE-FPVS 240
>AB028942-1|BAA82971.2| 2309|Homo sapiens KIAA1019 protein protein.
Length = 2309
Score = 31.1 bits (67), Expect = 3.6
Identities = 32/113 (28%), Positives = 49/113 (43%), Gaps = 7/113 (6%)
Frame = +3
Query: 171 LALKLGLFSPQDLEPAEPP--EKVLDEVSLDGIVRWIKSDRCKKIITLSGAG--ISTSAG 338
+ K G+ P +L+PA PP E+ + + S + + +++CK+I I
Sbjct: 2075 MCAKAGVPLPPNLKPAPPPTIEEKVAKKSGGATIEEL-TEKCKQIAQSKEDDDVIVNKPH 2133
Query: 339 IPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKP---FFTLAKELFPGS 488
+ D E YH+ K P+P F +N P P TL KE FP S
Sbjct: 2134 VSDEEEEEPPFYHHPFKLSEPKP-IFFNLNIAAAKPTPPKSQVTLTKE-FPVS 2184
>BC146792-1|AAI46793.1| 2624|Homo sapiens B double prime 1, subunit of
RNA polymerase III transcription initiation factor
protein.
Length = 2624
Score = 30.7 bits (66), Expect = 4.8
Identities = 18/74 (24%), Positives = 34/74 (45%), Gaps = 1/74 (1%)
Frame = +3
Query: 276 KSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEIN-FFRQNPKP 452
K + KK++T+S + I T +P PE +Y N + L + + + N R KP
Sbjct: 1610 KDETEKKVLTVSNSQIETEIEVPSSAVPEHRMYENQSQVVLVENLHVNKTNETIRHENKP 1669
Query: 453 FFTLAKELFPGSFK 494
+ + ++ F+
Sbjct: 1670 YVPSSAQMTRRKFQ 1683
>AJ279120-1|CAC21448.1| 2187|Homo sapiens TFNR protein.
Length = 2187
Score = 30.7 bits (66), Expect = 4.8
Identities = 18/74 (24%), Positives = 34/74 (45%), Gaps = 1/74 (1%)
Frame = +3
Query: 276 KSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEIN-FFRQNPKP 452
K + KK++T+S + I T +P PE +Y N + L + + + N R KP
Sbjct: 1610 KDETEKKVLTVSNSQIETEIEVPSSAVPEHRMYENQSQVVLVENLHVNKTNETIRHENKP 1669
Query: 453 FFTLAKELFPGSFK 494
+ + ++ F+
Sbjct: 1670 YVPSSAQMTRRKFQ 1683
>AJ238520-1|CAC04245.1| 2254|Homo sapiens putative transcription
factor-like nuclear regulator protein.
Length = 2254
Score = 30.7 bits (66), Expect = 4.8
Identities = 18/74 (24%), Positives = 34/74 (45%), Gaps = 1/74 (1%)
Frame = +3
Query: 276 KSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEIN-FFRQNPKP 452
K + KK++T+S + I T +P PE +Y N + L + + + N R KP
Sbjct: 1610 KDETEKKVLTVSNSQIETEIEVPSSAVPEHRMYENQSQVVLVENLHVNKTNETIRHENKP 1669
Query: 453 FFTLAKELFPGSFK 494
+ + ++ F+
Sbjct: 1670 YVPSSAQMTRRKFQ 1683
>AB051476-1|BAB21780.3| 2627|Homo sapiens KIAA1689 protein protein.
Length = 2627
Score = 30.7 bits (66), Expect = 4.8
Identities = 18/74 (24%), Positives = 34/74 (45%), Gaps = 1/74 (1%)
Frame = +3
Query: 276 KSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEIN-FFRQNPKP 452
K + KK++T+S + I T +P PE +Y N + L + + + N R KP
Sbjct: 1613 KDETEKKVLTVSNSQIETEIEVPSSAVPEHRMYENQSQVVLVENLHVNKTNETIRHENKP 1672
Query: 453 FFTLAKELFPGSFK 494
+ + ++ F+
Sbjct: 1673 YVPSSAQMTRRKFQ 1686
>U57057-1|AAB47807.1| 525|Homo sapiens WD protein IR10 protein.
Length = 525
Score = 30.3 bits (65), Expect = 6.3
Identities = 19/70 (27%), Positives = 30/70 (42%), Gaps = 5/70 (7%)
Frame = +1
Query: 34 RQIRLPEKVAVTKPWMSHRRMSRQQLRWKASEICFAISTWMT-----FECTWP*NSDSSA 198
R + EK+A W S + + RW A TW+T FEC P +++
Sbjct: 425 RLLNQTEKLAAEDGWRSSSLLEEKMPRWAAEHRLEEKKTWLTNGFDVFECP-PPKTENEL 483
Query: 199 LRILNRQNHQ 228
L++ RQ +
Sbjct: 484 LQMFYRQQEE 493
>BC011690-1|AAH11690.1| 525|Homo sapiens coronin, actin binding
protein, 2A protein.
Length = 525
Score = 30.3 bits (65), Expect = 6.3
Identities = 19/70 (27%), Positives = 30/70 (42%), Gaps = 5/70 (7%)
Frame = +1
Query: 34 RQIRLPEKVAVTKPWMSHRRMSRQQLRWKASEICFAISTWMT-----FECTWP*NSDSSA 198
R + EK+A W S + + RW A TW+T FEC P +++
Sbjct: 425 RLLNQTEKLAAEDGWRSSSLLEEKMPRWAAEHRLEEKKTWLTNGFDVFECP-PPKTENEL 483
Query: 199 LRILNRQNHQ 228
L++ RQ +
Sbjct: 484 LQMFYRQQEE 493
>BC000010-1|AAH00010.1| 525|Homo sapiens coronin, actin binding
protein, 2A protein.
Length = 525
Score = 30.3 bits (65), Expect = 6.3
Identities = 19/70 (27%), Positives = 30/70 (42%), Gaps = 5/70 (7%)
Frame = +1
Query: 34 RQIRLPEKVAVTKPWMSHRRMSRQQLRWKASEICFAISTWMT-----FECTWP*NSDSSA 198
R + EK+A W S + + RW A TW+T FEC P +++
Sbjct: 425 RLLNQTEKLAAEDGWRSSSLLEEKMPRWAAEHRLEEKKTWLTNGFDVFECP-PPKTENEL 483
Query: 199 LRILNRQNHQ 228
L++ RQ +
Sbjct: 484 LQMFYRQQEE 493
>AL137073-9|CAI13893.1| 525|Homo sapiens coronin, actin binding
protein, 2A protein.
Length = 525
Score = 30.3 bits (65), Expect = 6.3
Identities = 19/70 (27%), Positives = 30/70 (42%), Gaps = 5/70 (7%)
Frame = +1
Query: 34 RQIRLPEKVAVTKPWMSHRRMSRQQLRWKASEICFAISTWMT-----FECTWP*NSDSSA 198
R + EK+A W S + + RW A TW+T FEC P +++
Sbjct: 425 RLLNQTEKLAAEDGWRSSSLLEEKMPRWAAEHRLEEKKTWLTNGFDVFECP-PPKTENEL 483
Query: 199 LRILNRQNHQ 228
L++ RQ +
Sbjct: 484 LQMFYRQQEE 493
>M36428-1|AAA36624.1| 483|Homo sapiens protein ( Human son3 protein
gene, partial cds. ).
Length = 483
Score = 29.9 bits (64), Expect = 8.3
Identities = 25/98 (25%), Positives = 42/98 (42%), Gaps = 4/98 (4%)
Frame = +3
Query: 171 LALKLGLFSPQDLEPAEPP--EKVLDEVSLDGIVRWIKSDRCKKIITLSGAG--ISTSAG 338
+ K G+ P +L+PA PP E+ + + S + + +++CK+I I
Sbjct: 377 MCAKAGVPLPPNLKPAPPPTIEEKVAKKSGGATIEEL-TEKCKQIAQSKEDDDVIVNKPH 435
Query: 339 IPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKP 452
+ D E YH+ K P+P F +N P P
Sbjct: 436 VSDEEEEEPPFYHHPFKLSEPKP-IFFNLNIAAAKPTP 472
>AK128809-1|BAC87616.1| 404|Homo sapiens protein ( Homo sapiens
cDNA FLJ45978 fis, clone PROST2007444. ).
Length = 404
Score = 29.9 bits (64), Expect = 8.3
Identities = 16/45 (35%), Positives = 22/45 (48%)
Frame = -1
Query: 227 WWFCRFKILRAEESEF*GQVHSNVIHVEIAKHISEAFHRSCWRDI 93
WWFCRF +L AE VHS I ++ + F+ S +I
Sbjct: 361 WWFCRFPVLPAESDAV--TVHSTHGGFLIRFYVKDPFYISLHLEI 403
>AK096209-1|BAC04725.1| 446|Homo sapiens protein ( Homo sapiens
cDNA FLJ38890 fis, clone NESOP1000108. ).
Length = 446
Score = 29.9 bits (64), Expect = 8.3
Identities = 16/45 (35%), Positives = 22/45 (48%)
Frame = -1
Query: 227 WWFCRFKILRAEESEF*GQVHSNVIHVEIAKHISEAFHRSCWRDI 93
WWFCRF +L AE VHS I ++ + F+ S +I
Sbjct: 403 WWFCRFPVLPAESDAV--TVHSTHGGFLIRFYVKDPFYISLHLEI 445
>AK091762-1|BAC03741.1| 446|Homo sapiens P86 mRNA. protein.
Length = 446
Score = 29.9 bits (64), Expect = 8.3
Identities = 16/45 (35%), Positives = 22/45 (48%)
Frame = -1
Query: 227 WWFCRFKILRAEESEF*GQVHSNVIHVEIAKHISEAFHRSCWRDI 93
WWFCRF +L AE VHS I ++ + F+ S +I
Sbjct: 403 WWFCRFPVLPAESDAV--TVHSTHGGFLIRFYVKDPFYISLHLEI 445
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 101,158,139
Number of Sequences: 237096
Number of extensions: 2326702
Number of successful extensions: 5297
Number of sequences better than 10.0: 59
Number of HSP's better than 10.0 without gapping: 5096
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5274
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7366354010
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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