Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmte1e10
(658 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
CR533552-1|CAG38583.1| 509|Homo sapiens SPAG6 protein. 179 7e-45
BC030585-1|AAH30585.1| 458|Homo sapiens sperm associated antige... 179 7e-45
AL513128-4|CAH72210.1| 509|Homo sapiens sperm associated antige... 179 7e-45
AL513128-3|CAH72209.1| 458|Homo sapiens sperm associated antige... 179 7e-45
AL158211-15|CAI15963.1| 509|Homo sapiens sperm associated antig... 179 7e-45
AL158211-14|CAI15962.1| 458|Homo sapiens sperm associated antig... 179 7e-45
AF079363-1|AAC32590.1| 509|Homo sapiens sperm flagellar protein... 179 7e-45
AL513128-1|CAH72207.1| 246|Homo sapiens sperm associated antige... 123 6e-28
AL158211-12|CAI15960.1| 246|Homo sapiens sperm associated antig... 123 6e-28
AL513128-2|CAH72208.1| 191|Homo sapiens sperm associated antige... 79 2e-14
AL158211-13|CAI15961.1| 191|Homo sapiens sperm associated antig... 79 2e-14
Y12394-1|CAA73026.1| 521|Homo sapiens SRP1-like protein protein. 42 0.002
D89618-1|BAA20378.1| 521|Homo sapiens karyopherin alhph 3 protein. 42 0.002
BC035090-1|AAH35090.1| 521|Homo sapiens karyopherin alpha 3 (im... 42 0.002
BC024202-1|AAH24202.1| 521|Homo sapiens karyopherin alpha 3 (im... 42 0.002
BC017355-1|AAH17355.1| 521|Homo sapiens karyopherin alpha 3 (im... 42 0.002
AL136301-1|CAH71145.1| 521|Homo sapiens karyopherin alpha 3 (im... 42 0.002
AL135901-3|CAI40716.1| 521|Homo sapiens karyopherin alpha 3 (im... 42 0.002
AK223480-1|BAD97200.1| 521|Homo sapiens karyopherin alpha 3 var... 42 0.002
AF034756-1|AAB87693.1| 521|Homo sapiens importin-alpha homolog ... 42 0.002
AF005263-1|AAQ13404.1| 521|Homo sapiens importin alpha-3 subuni... 42 0.002
Y12393-1|CAA73025.1| 281|Homo sapiens SRP1-like protein protein. 40 0.010
U93240-1|AAC25605.1| 521|Homo sapiens importin alpha 3 protein. 40 0.010
BC034493-1|AAH34493.1| 521|Homo sapiens karyopherin alpha 4 (im... 40 0.010
BC028691-1|AAH28691.1| 521|Homo sapiens karyopherin alpha 4 (im... 40 0.010
AB002533-1|BAA19546.1| 521|Homo sapiens Qip1 protein. 40 0.010
U28386-1|AAA69957.1| 529|Homo sapiens hSRP1alpha protein. 36 0.096
U09559-1|AAA65700.1| 529|Homo sapiens Rch1 protein. 36 0.096
BC053343-1|AAH53343.1| 529|Homo sapiens karyopherin alpha 2 (RA... 36 0.096
AJ303086-1|CAC83080.1| 529|Homo sapiens karyopherin alpha 2 pro... 36 0.096
BT006665-1|AAP35311.1| 529|Homo sapiens karyopherin alpha 2 (RA... 36 0.17
BC005978-1|AAH05978.1| 529|Homo sapiens karyopherin alpha 2 (RA... 36 0.17
S75295-1|AAC60648.1| 538|Homo sapiens nucleoprotein interactor ... 35 0.22
CR456743-1|CAG33024.1| 538|Homo sapiens KPNA1 protein. 35 0.22
BT006959-1|AAP35605.1| 538|Homo sapiens karyopherin alpha 1 (im... 35 0.22
BC090864-1|AAH90864.1| 538|Homo sapiens karyopherin alpha 1 (im... 35 0.22
BC003009-1|AAH03009.1| 538|Homo sapiens karyopherin alpha 1 (im... 35 0.22
BC002374-1|AAH02374.1| 538|Homo sapiens karyopherin alpha 1 (im... 35 0.22
BT009843-1|AAP88845.1| 536|Homo sapiens karyopherin alpha 6 (im... 34 0.39
BC067848-1|AAH67848.1| 529|Homo sapiens karyopherin alpha 2 (RA... 34 0.39
BC020520-1|AAH20520.1| 536|Homo sapiens karyopherin alpha 6 (im... 34 0.39
AL445248-5|CAH71948.1| 536|Homo sapiens karyopherin alpha 6 (im... 34 0.39
AL049795-3|CAI22056.1| 536|Homo sapiens karyopherin alpha 6 (im... 34 0.39
AL049795-1|CAI22054.1| 321|Homo sapiens karyopherin alpha 6 (im... 34 0.39
AF060543-1|AAC15233.1| 536|Homo sapiens importin alpha 7 subuni... 34 0.39
BC047409-1|AAH47409.1| 539|Homo sapiens karyopherin alpha 5 (im... 33 0.90
AL132795-5|CAI20500.1| 539|Homo sapiens karyopherin alpha 5 (im... 33 0.90
AF005361-1|AAC51868.1| 536|Homo sapiens importin alpha 6 protein. 33 0.90
AK126073-1|BAC86425.1| 1080|Homo sapiens protein ( Homo sapiens ... 32 2.1
AK058144-1|BAB71684.1| 237|Homo sapiens protein ( Homo sapiens ... 32 2.1
AJ549812-1|CAD71147.1| 1363|Homo sapiens hypothetical protein pr... 32 2.1
AL390866-5|CAI12711.1| 1044|Homo sapiens novel protein protein. 31 2.7
AL355372-1|CAI16402.1| 1044|Homo sapiens novel protein protein. 31 2.7
>CR533552-1|CAG38583.1| 509|Homo sapiens SPAG6 protein.
Length = 509
Score = 179 bits (436), Expect = 7e-45
Identities = 89/177 (50%), Positives = 125/177 (70%)
Frame = +3
Query: 126 RNIQLVFETYQKARLVFVQTMAELATRSSNVKCLESAGVLELLKPLLSDACSTIRQCAVV 305
R + VFE YQKAR FVQ +AELATR N++ L++AGV+ LL+ LL D TI+Q A +
Sbjct: 4 RQVLQVFEQYQKARTQFVQMVAELATRPQNIETLQNAGVMSLLRTLLLDVVPTIQQTAAL 63
Query: 306 AIAKLAEHDLDIARQLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELASAIVR 485
A+ +LA ++ D+A ++ I+ + +L + N +YK++A ++LRAV KH+ +LA AIV
Sbjct: 64 ALGRLANYNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQLAQAIVD 123
Query: 486 LGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQLAGLVVDAGTLPLLVLAFQEPE 656
GAL+ +V CLEDFD VKE AAWA+ YI +H+ +L+ VVDAG +PLLVL QEPE
Sbjct: 124 CGALDTLVICLEDFDPGVKEAAAWALRYIARHNAELSRAVVDAGAVPLLVLCIQEPE 180
Score = 74.9 bits (176), Expect = 2e-13
Identities = 40/168 (23%), Positives = 88/168 (52%)
Frame = +3
Query: 153 YQKARLVFVQTMAELATRSSNVKCLESAGVLELLKPLLSDACSTIRQCAVVAIAKLAEHD 332
Y+KA ++ + + + + + + + G L+ L L D +++ A A+ +A H+
Sbjct: 99 YKKAAAFVLRAVGKHSPQLA--QAIVDCGALDTLVICLEDFDPGVKEAAAWALRYIARHN 156
Query: 333 LDIARQLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELASAIVRLGALEHIVS 512
+++R +++ G + + + + + + KR A L +AKH+ ELA +V GA+ H+
Sbjct: 157 AELSRAVVDAGAVPLLVLCIQEPEIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQ 216
Query: 513 CLEDFDTQVKENAAWAVGYIGKHSEQLAGLVVDAGTLPLLVLAFQEPE 656
+ + D ++K A+ + KHS LA +VV+A P+++ ++ +
Sbjct: 217 MILNPDAKLKHQILSALSQVSKHSVDLAEMVVEAEIFPVVLTCLKDKD 264
Score = 73.7 bits (173), Expect = 5e-13
Identities = 38/164 (23%), Positives = 83/164 (50%), Gaps = 2/164 (1%)
Frame = +3
Query: 171 VFVQTMAELATRSSNV-KCLESAGVLELLKPLLSDACSTIRQCAVVAIAKLAEHDLDIAR 347
+ ++++A S + + + AG + L ++ + + ++ + A++++++H +D+A
Sbjct: 186 IAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSKHSVDLAE 245
Query: 348 QLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELASAIVRLGALEHIVSCLEDF 527
++ I + L L + Y K++A L+R +AKH EL+ +V G + ++ C+
Sbjct: 246 MVVEAEIFPVVLTCLKDKDEYVKKNASTLIREIAKHTPELSQLVVNAGGVAAVIDCIGSC 305
Query: 528 DTQVKENAAWAVGYIGKHSEQLA-GLVVDAGTLPLLVLAFQEPE 656
+ +GY+ HSE LA +++ G L V +EPE
Sbjct: 306 KGNTRLPGIMMLGYVAAHSENLAMAVIISKGVPQLSVCLSEEPE 349
Score = 69.7 bits (163), Expect = 8e-12
Identities = 36/139 (25%), Positives = 76/139 (54%)
Frame = +3
Query: 219 KCLESAGVLELLKPLLSDACSTIRQCAVVAIAKLAEHDLDIARQLLNGGIITITLENLNK 398
+ + AG + LL + + +++ A A++ +A+H ++A+ +++ G + + +
Sbjct: 161 RAVVDAGAVPLLVLCIQEPEIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILN 220
Query: 399 YNVYYKRSALYLLRAVAKHNEELASAIVRLGALEHIVSCLEDFDTQVKENAAWAVGYIGK 578
+ K L L V+KH+ +LA +V +++CL+D D VK+NA+ + I K
Sbjct: 221 PDAKLKHQILSALSQVSKHSVDLAEMVVEAEIFPVVLTCLKDKDEYVKKNASTLIREIAK 280
Query: 579 HSEQLAGLVVDAGTLPLLV 635
H+ +L+ LVV+AG + ++
Sbjct: 281 HTPELSQLVVNAGGVAAVI 299
Score = 67.7 bits (158), Expect = 3e-11
Identities = 39/176 (22%), Positives = 89/176 (50%), Gaps = 2/176 (1%)
Frame = +3
Query: 135 QLVFETYQKARLVFVQTMAELATRSSNV-KCLESAGVLELLKPLLSDACSTIRQCAVVAI 311
Q++ K + + +++++ S ++ + + A + ++ L D +++ A I
Sbjct: 216 QMILNPDAKLKHQILSALSQVSKHSVDLAEMVVEAEIFPVVLTCLKDKDEYVKKNASTLI 275
Query: 312 AKLAEHDLDIARQLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELASAIVRLG 491
++A+H ++++ ++N G + ++ + + + +L VA H+E LA A++
Sbjct: 276 REIAKHTPELSQLVVNAGGVAAVIDCIGSCKGNTRLPGIMMLGYVAAHSENLAMAVIISK 335
Query: 492 ALEHIVSCL-EDFDTQVKENAAWAVGYIGKHSEQLAGLVVDAGTLPLLVLAFQEPE 656
+ + CL E+ + +K AAWA+G IG+H+ + A V TLP+L+ + E
Sbjct: 336 GVPQLSVCLSEEPEDHIKAAAAWALGQIGRHTPEHARAVAVTNTLPVLLSLYMSTE 391
>BC030585-1|AAH30585.1| 458|Homo sapiens sperm associated antigen 6
protein.
Length = 458
Score = 179 bits (436), Expect = 7e-45
Identities = 89/177 (50%), Positives = 125/177 (70%)
Frame = +3
Query: 126 RNIQLVFETYQKARLVFVQTMAELATRSSNVKCLESAGVLELLKPLLSDACSTIRQCAVV 305
R + VFE YQKAR FVQ +AELATR N++ L++AGV+ LL+ LL D TI+Q A +
Sbjct: 4 RQVLQVFEQYQKARTQFVQMVAELATRPQNIETLQNAGVMSLLRTLLLDVVPTIQQIAAL 63
Query: 306 AIAKLAEHDLDIARQLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELASAIVR 485
A+ +LA ++ D+A ++ I+ + +L + N +YK++A ++LRAV KH+ +LA AIV
Sbjct: 64 ALGRLANYNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQLAQAIVD 123
Query: 486 LGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQLAGLVVDAGTLPLLVLAFQEPE 656
GAL+ +V CLEDFD VKE AAWA+ YI +H+ +L+ VVDAG +PLLVL QEPE
Sbjct: 124 CGALDTLVICLEDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEPE 180
Score = 72.5 bits (170), Expect = 1e-12
Identities = 36/142 (25%), Positives = 73/142 (51%), Gaps = 1/142 (0%)
Frame = +3
Query: 234 AGVLELLKPLLSDACSTIRQCAVVAIAKLAEHDLDIARQLLNGGIITITLENLNKYNVYY 413
AG + L ++ + + ++ + A++++++H +D+A ++ I + L L + Y
Sbjct: 208 AGAVAHLAQMILNPDAKLKHQILSALSQVSKHSVDLAEMVVEAEIFPVVLTCLKDKDEYV 267
Query: 414 KRSALYLLRAVAKHNEELASAIVRLGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQL 593
K++A L+R +AKH EL+ +V G + ++ C+ + +GY+ HSE L
Sbjct: 268 KKNASTLIREIAKHTPELSQLVVNAGGVAAVIDCIGSCKGNTRLPGIMMLGYVAAHSENL 327
Query: 594 A-GLVVDAGTLPLLVLAFQEPE 656
A +++ G L V +EPE
Sbjct: 328 AMAVIISKGVPQLSVCLSEEPE 349
Score = 68.9 bits (161), Expect = 1e-11
Identities = 37/168 (22%), Positives = 86/168 (51%)
Frame = +3
Query: 153 YQKARLVFVQTMAELATRSSNVKCLESAGVLELLKPLLSDACSTIRQCAVVAIAKLAEHD 332
Y+KA ++ + + + + + + + G L+ L L D +++ A A+ +A H+
Sbjct: 99 YKKAAAFVLRAVGKHSPQLA--QAIVDCGALDTLVICLEDFDPGVKEAAAWALRYIARHN 156
Query: 333 LDIARQLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELASAIVRLGALEHIVS 512
++++ +++ G + + + + + + K A L + KH+ ELA +V GA+ H+
Sbjct: 157 AELSQAVVDAGAVPLLVLCIQEPEIALKGIAASALSDIVKHSPELAQTVVDAGAVAHLAQ 216
Query: 513 CLEDFDTQVKENAAWAVGYIGKHSEQLAGLVVDAGTLPLLVLAFQEPE 656
+ + D ++K A+ + KHS LA +VV+A P+++ ++ +
Sbjct: 217 MILNPDAKLKHQILSALSQVSKHSVDLAEMVVEAEIFPVVLTCLKDKD 264
Score = 67.7 bits (158), Expect = 3e-11
Identities = 39/176 (22%), Positives = 89/176 (50%), Gaps = 2/176 (1%)
Frame = +3
Query: 135 QLVFETYQKARLVFVQTMAELATRSSNV-KCLESAGVLELLKPLLSDACSTIRQCAVVAI 311
Q++ K + + +++++ S ++ + + A + ++ L D +++ A I
Sbjct: 216 QMILNPDAKLKHQILSALSQVSKHSVDLAEMVVEAEIFPVVLTCLKDKDEYVKKNASTLI 275
Query: 312 AKLAEHDLDIARQLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELASAIVRLG 491
++A+H ++++ ++N G + ++ + + + +L VA H+E LA A++
Sbjct: 276 REIAKHTPELSQLVVNAGGVAAVIDCIGSCKGNTRLPGIMMLGYVAAHSENLAMAVIISK 335
Query: 492 ALEHIVSCL-EDFDTQVKENAAWAVGYIGKHSEQLAGLVVDAGTLPLLVLAFQEPE 656
+ + CL E+ + +K AAWA+G IG+H+ + A V TLP+L+ + E
Sbjct: 336 GVPQLSVCLSEEPEDHIKAAAAWALGQIGRHTPEHARAVAVTNTLPVLLSLYMSTE 391
Score = 66.5 bits (155), Expect = 8e-11
Identities = 35/134 (26%), Positives = 72/134 (53%)
Frame = +3
Query: 234 AGVLELLKPLLSDACSTIRQCAVVAIAKLAEHDLDIARQLLNGGIITITLENLNKYNVYY 413
AG + LL + + ++ A A++ + +H ++A+ +++ G + + + +
Sbjct: 166 AGAVPLLVLCIQEPEIALKGIAASALSDIVKHSPELAQTVVDAGAVAHLAQMILNPDAKL 225
Query: 414 KRSALYLLRAVAKHNEELASAIVRLGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQL 593
K L L V+KH+ +LA +V +++CL+D D VK+NA+ + I KH+ +L
Sbjct: 226 KHQILSALSQVSKHSVDLAEMVVEAEIFPVVLTCLKDKDEYVKKNASTLIREIAKHTPEL 285
Query: 594 AGLVVDAGTLPLLV 635
+ LVV+AG + ++
Sbjct: 286 SQLVVNAGGVAAVI 299
>AL513128-4|CAH72210.1| 509|Homo sapiens sperm associated antigen 6
protein.
Length = 509
Score = 179 bits (436), Expect = 7e-45
Identities = 89/177 (50%), Positives = 125/177 (70%)
Frame = +3
Query: 126 RNIQLVFETYQKARLVFVQTMAELATRSSNVKCLESAGVLELLKPLLSDACSTIRQCAVV 305
R + VFE YQKAR FVQ +AELATR N++ L++AGV+ LL+ LL D TI+Q A +
Sbjct: 4 RQVLQVFEQYQKARTQFVQMVAELATRPQNIETLQNAGVMSLLRTLLLDVVPTIQQTAAL 63
Query: 306 AIAKLAEHDLDIARQLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELASAIVR 485
A+ +LA ++ D+A ++ I+ + +L + N +YK++A ++LRAV KH+ +LA AIV
Sbjct: 64 ALGRLANYNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQLAQAIVD 123
Query: 486 LGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQLAGLVVDAGTLPLLVLAFQEPE 656
GAL+ +V CLEDFD VKE AAWA+ YI +H+ +L+ VVDAG +PLLVL QEPE
Sbjct: 124 CGALDTLVICLEDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEPE 180
Score = 73.7 bits (173), Expect = 5e-13
Identities = 38/164 (23%), Positives = 83/164 (50%), Gaps = 2/164 (1%)
Frame = +3
Query: 171 VFVQTMAELATRSSNV-KCLESAGVLELLKPLLSDACSTIRQCAVVAIAKLAEHDLDIAR 347
+ ++++A S + + + AG + L ++ + + ++ + A++++++H +D+A
Sbjct: 186 IAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSKHSVDLAE 245
Query: 348 QLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELASAIVRLGALEHIVSCLEDF 527
++ I + L L + Y K++A L+R +AKH EL+ +V G + ++ C+
Sbjct: 246 MVVEAEIFPVVLTCLKDKDEYVKKNASTLIREIAKHTPELSQLVVNAGGVAAVIDCIGSC 305
Query: 528 DTQVKENAAWAVGYIGKHSEQLA-GLVVDAGTLPLLVLAFQEPE 656
+ +GY+ HSE LA +++ G L V +EPE
Sbjct: 306 KGNTRLPGIMMLGYVAAHSENLAMAVIISKGVPQLSVCLSEEPE 349
Score = 73.3 bits (172), Expect = 7e-13
Identities = 39/168 (23%), Positives = 88/168 (52%)
Frame = +3
Query: 153 YQKARLVFVQTMAELATRSSNVKCLESAGVLELLKPLLSDACSTIRQCAVVAIAKLAEHD 332
Y+KA ++ + + + + + + + G L+ L L D +++ A A+ +A H+
Sbjct: 99 YKKAAAFVLRAVGKHSPQLA--QAIVDCGALDTLVICLEDFDPGVKEAAAWALRYIARHN 156
Query: 333 LDIARQLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELASAIVRLGALEHIVS 512
++++ +++ G + + + + + + KR A L +AKH+ ELA +V GA+ H+
Sbjct: 157 AELSQAVVDAGAVPLLVLCIQEPEIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQ 216
Query: 513 CLEDFDTQVKENAAWAVGYIGKHSEQLAGLVVDAGTLPLLVLAFQEPE 656
+ + D ++K A+ + KHS LA +VV+A P+++ ++ +
Sbjct: 217 MILNPDAKLKHQILSALSQVSKHSVDLAEMVVEAEIFPVVLTCLKDKD 264
Score = 69.3 bits (162), Expect = 1e-11
Identities = 36/134 (26%), Positives = 74/134 (55%)
Frame = +3
Query: 234 AGVLELLKPLLSDACSTIRQCAVVAIAKLAEHDLDIARQLLNGGIITITLENLNKYNVYY 413
AG + LL + + +++ A A++ +A+H ++A+ +++ G + + + +
Sbjct: 166 AGAVPLLVLCIQEPEIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKL 225
Query: 414 KRSALYLLRAVAKHNEELASAIVRLGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQL 593
K L L V+KH+ +LA +V +++CL+D D VK+NA+ + I KH+ +L
Sbjct: 226 KHQILSALSQVSKHSVDLAEMVVEAEIFPVVLTCLKDKDEYVKKNASTLIREIAKHTPEL 285
Query: 594 AGLVVDAGTLPLLV 635
+ LVV+AG + ++
Sbjct: 286 SQLVVNAGGVAAVI 299
Score = 67.7 bits (158), Expect = 3e-11
Identities = 39/176 (22%), Positives = 89/176 (50%), Gaps = 2/176 (1%)
Frame = +3
Query: 135 QLVFETYQKARLVFVQTMAELATRSSNV-KCLESAGVLELLKPLLSDACSTIRQCAVVAI 311
Q++ K + + +++++ S ++ + + A + ++ L D +++ A I
Sbjct: 216 QMILNPDAKLKHQILSALSQVSKHSVDLAEMVVEAEIFPVVLTCLKDKDEYVKKNASTLI 275
Query: 312 AKLAEHDLDIARQLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELASAIVRLG 491
++A+H ++++ ++N G + ++ + + + +L VA H+E LA A++
Sbjct: 276 REIAKHTPELSQLVVNAGGVAAVIDCIGSCKGNTRLPGIMMLGYVAAHSENLAMAVIISK 335
Query: 492 ALEHIVSCL-EDFDTQVKENAAWAVGYIGKHSEQLAGLVVDAGTLPLLVLAFQEPE 656
+ + CL E+ + +K AAWA+G IG+H+ + A V TLP+L+ + E
Sbjct: 336 GVPQLSVCLSEEPEDHIKAAAAWALGQIGRHTPEHARAVAVTNTLPVLLSLYMSTE 391
>AL513128-3|CAH72209.1| 458|Homo sapiens sperm associated antigen 6
protein.
Length = 458
Score = 179 bits (436), Expect = 7e-45
Identities = 89/177 (50%), Positives = 125/177 (70%)
Frame = +3
Query: 126 RNIQLVFETYQKARLVFVQTMAELATRSSNVKCLESAGVLELLKPLLSDACSTIRQCAVV 305
R + VFE YQKAR FVQ +AELATR N++ L++AGV+ LL+ LL D TI+Q A +
Sbjct: 4 RQVLQVFEQYQKARTQFVQMVAELATRPQNIETLQNAGVMSLLRTLLLDVVPTIQQTAAL 63
Query: 306 AIAKLAEHDLDIARQLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELASAIVR 485
A+ +LA ++ D+A ++ I+ + +L + N +YK++A ++LRAV KH+ +LA AIV
Sbjct: 64 ALGRLANYNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQLAQAIVD 123
Query: 486 LGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQLAGLVVDAGTLPLLVLAFQEPE 656
GAL+ +V CLEDFD VKE AAWA+ YI +H+ +L+ VVDAG +PLLVL QEPE
Sbjct: 124 CGALDTLVICLEDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEPE 180
Score = 73.7 bits (173), Expect = 5e-13
Identities = 38/164 (23%), Positives = 83/164 (50%), Gaps = 2/164 (1%)
Frame = +3
Query: 171 VFVQTMAELATRSSNV-KCLESAGVLELLKPLLSDACSTIRQCAVVAIAKLAEHDLDIAR 347
+ ++++A S + + + AG + L ++ + + ++ + A++++++H +D+A
Sbjct: 186 IAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSKHSVDLAE 245
Query: 348 QLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELASAIVRLGALEHIVSCLEDF 527
++ I + L L + Y K++A L+R +AKH EL+ +V G + ++ C+
Sbjct: 246 MVVEAEIFPVVLTCLKDKDEYVKKNASTLIREIAKHTPELSQLVVNAGGVAAVIDCIGSC 305
Query: 528 DTQVKENAAWAVGYIGKHSEQLA-GLVVDAGTLPLLVLAFQEPE 656
+ +GY+ HSE LA +++ G L V +EPE
Sbjct: 306 KGNTRLPGIMMLGYVAAHSENLAMAVIISKGVPQLSVCLSEEPE 349
Score = 73.3 bits (172), Expect = 7e-13
Identities = 39/168 (23%), Positives = 88/168 (52%)
Frame = +3
Query: 153 YQKARLVFVQTMAELATRSSNVKCLESAGVLELLKPLLSDACSTIRQCAVVAIAKLAEHD 332
Y+KA ++ + + + + + + + G L+ L L D +++ A A+ +A H+
Sbjct: 99 YKKAAAFVLRAVGKHSPQLA--QAIVDCGALDTLVICLEDFDPGVKEAAAWALRYIARHN 156
Query: 333 LDIARQLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELASAIVRLGALEHIVS 512
++++ +++ G + + + + + + KR A L +AKH+ ELA +V GA+ H+
Sbjct: 157 AELSQAVVDAGAVPLLVLCIQEPEIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQ 216
Query: 513 CLEDFDTQVKENAAWAVGYIGKHSEQLAGLVVDAGTLPLLVLAFQEPE 656
+ + D ++K A+ + KHS LA +VV+A P+++ ++ +
Sbjct: 217 MILNPDAKLKHQILSALSQVSKHSVDLAEMVVEAEIFPVVLTCLKDKD 264
Score = 69.3 bits (162), Expect = 1e-11
Identities = 36/134 (26%), Positives = 74/134 (55%)
Frame = +3
Query: 234 AGVLELLKPLLSDACSTIRQCAVVAIAKLAEHDLDIARQLLNGGIITITLENLNKYNVYY 413
AG + LL + + +++ A A++ +A+H ++A+ +++ G + + + +
Sbjct: 166 AGAVPLLVLCIQEPEIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKL 225
Query: 414 KRSALYLLRAVAKHNEELASAIVRLGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQL 593
K L L V+KH+ +LA +V +++CL+D D VK+NA+ + I KH+ +L
Sbjct: 226 KHQILSALSQVSKHSVDLAEMVVEAEIFPVVLTCLKDKDEYVKKNASTLIREIAKHTPEL 285
Query: 594 AGLVVDAGTLPLLV 635
+ LVV+AG + ++
Sbjct: 286 SQLVVNAGGVAAVI 299
Score = 67.7 bits (158), Expect = 3e-11
Identities = 39/176 (22%), Positives = 89/176 (50%), Gaps = 2/176 (1%)
Frame = +3
Query: 135 QLVFETYQKARLVFVQTMAELATRSSNV-KCLESAGVLELLKPLLSDACSTIRQCAVVAI 311
Q++ K + + +++++ S ++ + + A + ++ L D +++ A I
Sbjct: 216 QMILNPDAKLKHQILSALSQVSKHSVDLAEMVVEAEIFPVVLTCLKDKDEYVKKNASTLI 275
Query: 312 AKLAEHDLDIARQLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELASAIVRLG 491
++A+H ++++ ++N G + ++ + + + +L VA H+E LA A++
Sbjct: 276 REIAKHTPELSQLVVNAGGVAAVIDCIGSCKGNTRLPGIMMLGYVAAHSENLAMAVIISK 335
Query: 492 ALEHIVSCL-EDFDTQVKENAAWAVGYIGKHSEQLAGLVVDAGTLPLLVLAFQEPE 656
+ + CL E+ + +K AAWA+G IG+H+ + A V TLP+L+ + E
Sbjct: 336 GVPQLSVCLSEEPEDHIKAAAAWALGQIGRHTPEHARAVAVTNTLPVLLSLYMSTE 391
>AL158211-15|CAI15963.1| 509|Homo sapiens sperm associated antigen
6 protein.
Length = 509
Score = 179 bits (436), Expect = 7e-45
Identities = 89/177 (50%), Positives = 125/177 (70%)
Frame = +3
Query: 126 RNIQLVFETYQKARLVFVQTMAELATRSSNVKCLESAGVLELLKPLLSDACSTIRQCAVV 305
R + VFE YQKAR FVQ +AELATR N++ L++AGV+ LL+ LL D TI+Q A +
Sbjct: 4 RQVLQVFEQYQKARTQFVQMVAELATRPQNIETLQNAGVMSLLRTLLLDVVPTIQQTAAL 63
Query: 306 AIAKLAEHDLDIARQLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELASAIVR 485
A+ +LA ++ D+A ++ I+ + +L + N +YK++A ++LRAV KH+ +LA AIV
Sbjct: 64 ALGRLANYNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQLAQAIVD 123
Query: 486 LGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQLAGLVVDAGTLPLLVLAFQEPE 656
GAL+ +V CLEDFD VKE AAWA+ YI +H+ +L+ VVDAG +PLLVL QEPE
Sbjct: 124 CGALDTLVICLEDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEPE 180
Score = 73.7 bits (173), Expect = 5e-13
Identities = 38/164 (23%), Positives = 83/164 (50%), Gaps = 2/164 (1%)
Frame = +3
Query: 171 VFVQTMAELATRSSNV-KCLESAGVLELLKPLLSDACSTIRQCAVVAIAKLAEHDLDIAR 347
+ ++++A S + + + AG + L ++ + + ++ + A++++++H +D+A
Sbjct: 186 IAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSKHSVDLAE 245
Query: 348 QLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELASAIVRLGALEHIVSCLEDF 527
++ I + L L + Y K++A L+R +AKH EL+ +V G + ++ C+
Sbjct: 246 MVVEAEIFPVVLTCLKDKDEYVKKNASTLIREIAKHTPELSQLVVNAGGVAAVIDCIGSC 305
Query: 528 DTQVKENAAWAVGYIGKHSEQLA-GLVVDAGTLPLLVLAFQEPE 656
+ +GY+ HSE LA +++ G L V +EPE
Sbjct: 306 KGNTRLPGIMMLGYVAAHSENLAMAVIISKGVPQLSVCLSEEPE 349
Score = 73.3 bits (172), Expect = 7e-13
Identities = 39/168 (23%), Positives = 88/168 (52%)
Frame = +3
Query: 153 YQKARLVFVQTMAELATRSSNVKCLESAGVLELLKPLLSDACSTIRQCAVVAIAKLAEHD 332
Y+KA ++ + + + + + + + G L+ L L D +++ A A+ +A H+
Sbjct: 99 YKKAAAFVLRAVGKHSPQLA--QAIVDCGALDTLVICLEDFDPGVKEAAAWALRYIARHN 156
Query: 333 LDIARQLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELASAIVRLGALEHIVS 512
++++ +++ G + + + + + + KR A L +AKH+ ELA +V GA+ H+
Sbjct: 157 AELSQAVVDAGAVPLLVLCIQEPEIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQ 216
Query: 513 CLEDFDTQVKENAAWAVGYIGKHSEQLAGLVVDAGTLPLLVLAFQEPE 656
+ + D ++K A+ + KHS LA +VV+A P+++ ++ +
Sbjct: 217 MILNPDAKLKHQILSALSQVSKHSVDLAEMVVEAEIFPVVLTCLKDKD 264
Score = 69.3 bits (162), Expect = 1e-11
Identities = 36/134 (26%), Positives = 74/134 (55%)
Frame = +3
Query: 234 AGVLELLKPLLSDACSTIRQCAVVAIAKLAEHDLDIARQLLNGGIITITLENLNKYNVYY 413
AG + LL + + +++ A A++ +A+H ++A+ +++ G + + + +
Sbjct: 166 AGAVPLLVLCIQEPEIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKL 225
Query: 414 KRSALYLLRAVAKHNEELASAIVRLGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQL 593
K L L V+KH+ +LA +V +++CL+D D VK+NA+ + I KH+ +L
Sbjct: 226 KHQILSALSQVSKHSVDLAEMVVEAEIFPVVLTCLKDKDEYVKKNASTLIREIAKHTPEL 285
Query: 594 AGLVVDAGTLPLLV 635
+ LVV+AG + ++
Sbjct: 286 SQLVVNAGGVAAVI 299
Score = 67.7 bits (158), Expect = 3e-11
Identities = 39/176 (22%), Positives = 89/176 (50%), Gaps = 2/176 (1%)
Frame = +3
Query: 135 QLVFETYQKARLVFVQTMAELATRSSNV-KCLESAGVLELLKPLLSDACSTIRQCAVVAI 311
Q++ K + + +++++ S ++ + + A + ++ L D +++ A I
Sbjct: 216 QMILNPDAKLKHQILSALSQVSKHSVDLAEMVVEAEIFPVVLTCLKDKDEYVKKNASTLI 275
Query: 312 AKLAEHDLDIARQLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELASAIVRLG 491
++A+H ++++ ++N G + ++ + + + +L VA H+E LA A++
Sbjct: 276 REIAKHTPELSQLVVNAGGVAAVIDCIGSCKGNTRLPGIMMLGYVAAHSENLAMAVIISK 335
Query: 492 ALEHIVSCL-EDFDTQVKENAAWAVGYIGKHSEQLAGLVVDAGTLPLLVLAFQEPE 656
+ + CL E+ + +K AAWA+G IG+H+ + A V TLP+L+ + E
Sbjct: 336 GVPQLSVCLSEEPEDHIKAAAAWALGQIGRHTPEHARAVAVTNTLPVLLSLYMSTE 391
>AL158211-14|CAI15962.1| 458|Homo sapiens sperm associated antigen
6 protein.
Length = 458
Score = 179 bits (436), Expect = 7e-45
Identities = 89/177 (50%), Positives = 125/177 (70%)
Frame = +3
Query: 126 RNIQLVFETYQKARLVFVQTMAELATRSSNVKCLESAGVLELLKPLLSDACSTIRQCAVV 305
R + VFE YQKAR FVQ +AELATR N++ L++AGV+ LL+ LL D TI+Q A +
Sbjct: 4 RQVLQVFEQYQKARTQFVQMVAELATRPQNIETLQNAGVMSLLRTLLLDVVPTIQQTAAL 63
Query: 306 AIAKLAEHDLDIARQLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELASAIVR 485
A+ +LA ++ D+A ++ I+ + +L + N +YK++A ++LRAV KH+ +LA AIV
Sbjct: 64 ALGRLANYNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQLAQAIVD 123
Query: 486 LGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQLAGLVVDAGTLPLLVLAFQEPE 656
GAL+ +V CLEDFD VKE AAWA+ YI +H+ +L+ VVDAG +PLLVL QEPE
Sbjct: 124 CGALDTLVICLEDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEPE 180
Score = 73.7 bits (173), Expect = 5e-13
Identities = 38/164 (23%), Positives = 83/164 (50%), Gaps = 2/164 (1%)
Frame = +3
Query: 171 VFVQTMAELATRSSNV-KCLESAGVLELLKPLLSDACSTIRQCAVVAIAKLAEHDLDIAR 347
+ ++++A S + + + AG + L ++ + + ++ + A++++++H +D+A
Sbjct: 186 IAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSKHSVDLAE 245
Query: 348 QLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELASAIVRLGALEHIVSCLEDF 527
++ I + L L + Y K++A L+R +AKH EL+ +V G + ++ C+
Sbjct: 246 MVVEAEIFPVVLTCLKDKDEYVKKNASTLIREIAKHTPELSQLVVNAGGVAAVIDCIGSC 305
Query: 528 DTQVKENAAWAVGYIGKHSEQLA-GLVVDAGTLPLLVLAFQEPE 656
+ +GY+ HSE LA +++ G L V +EPE
Sbjct: 306 KGNTRLPGIMMLGYVAAHSENLAMAVIISKGVPQLSVCLSEEPE 349
Score = 73.3 bits (172), Expect = 7e-13
Identities = 39/168 (23%), Positives = 88/168 (52%)
Frame = +3
Query: 153 YQKARLVFVQTMAELATRSSNVKCLESAGVLELLKPLLSDACSTIRQCAVVAIAKLAEHD 332
Y+KA ++ + + + + + + + G L+ L L D +++ A A+ +A H+
Sbjct: 99 YKKAAAFVLRAVGKHSPQLA--QAIVDCGALDTLVICLEDFDPGVKEAAAWALRYIARHN 156
Query: 333 LDIARQLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELASAIVRLGALEHIVS 512
++++ +++ G + + + + + + KR A L +AKH+ ELA +V GA+ H+
Sbjct: 157 AELSQAVVDAGAVPLLVLCIQEPEIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQ 216
Query: 513 CLEDFDTQVKENAAWAVGYIGKHSEQLAGLVVDAGTLPLLVLAFQEPE 656
+ + D ++K A+ + KHS LA +VV+A P+++ ++ +
Sbjct: 217 MILNPDAKLKHQILSALSQVSKHSVDLAEMVVEAEIFPVVLTCLKDKD 264
Score = 69.3 bits (162), Expect = 1e-11
Identities = 36/134 (26%), Positives = 74/134 (55%)
Frame = +3
Query: 234 AGVLELLKPLLSDACSTIRQCAVVAIAKLAEHDLDIARQLLNGGIITITLENLNKYNVYY 413
AG + LL + + +++ A A++ +A+H ++A+ +++ G + + + +
Sbjct: 166 AGAVPLLVLCIQEPEIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKL 225
Query: 414 KRSALYLLRAVAKHNEELASAIVRLGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQL 593
K L L V+KH+ +LA +V +++CL+D D VK+NA+ + I KH+ +L
Sbjct: 226 KHQILSALSQVSKHSVDLAEMVVEAEIFPVVLTCLKDKDEYVKKNASTLIREIAKHTPEL 285
Query: 594 AGLVVDAGTLPLLV 635
+ LVV+AG + ++
Sbjct: 286 SQLVVNAGGVAAVI 299
Score = 67.7 bits (158), Expect = 3e-11
Identities = 39/176 (22%), Positives = 89/176 (50%), Gaps = 2/176 (1%)
Frame = +3
Query: 135 QLVFETYQKARLVFVQTMAELATRSSNV-KCLESAGVLELLKPLLSDACSTIRQCAVVAI 311
Q++ K + + +++++ S ++ + + A + ++ L D +++ A I
Sbjct: 216 QMILNPDAKLKHQILSALSQVSKHSVDLAEMVVEAEIFPVVLTCLKDKDEYVKKNASTLI 275
Query: 312 AKLAEHDLDIARQLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELASAIVRLG 491
++A+H ++++ ++N G + ++ + + + +L VA H+E LA A++
Sbjct: 276 REIAKHTPELSQLVVNAGGVAAVIDCIGSCKGNTRLPGIMMLGYVAAHSENLAMAVIISK 335
Query: 492 ALEHIVSCL-EDFDTQVKENAAWAVGYIGKHSEQLAGLVVDAGTLPLLVLAFQEPE 656
+ + CL E+ + +K AAWA+G IG+H+ + A V TLP+L+ + E
Sbjct: 336 GVPQLSVCLSEEPEDHIKAAAAWALGQIGRHTPEHARAVAVTNTLPVLLSLYMSTE 391
>AF079363-1|AAC32590.1| 509|Homo sapiens sperm flagellar protein
Repro-SA-1 protein.
Length = 509
Score = 179 bits (436), Expect = 7e-45
Identities = 89/177 (50%), Positives = 125/177 (70%)
Frame = +3
Query: 126 RNIQLVFETYQKARLVFVQTMAELATRSSNVKCLESAGVLELLKPLLSDACSTIRQCAVV 305
R + VFE YQKAR FVQ +AELATR N++ L++AGV+ LL+ LL D TI+Q A +
Sbjct: 4 RQVLQVFEQYQKARTQFVQMVAELATRPQNIETLQNAGVMSLLRTLLLDVVPTIQQTAAL 63
Query: 306 AIAKLAEHDLDIARQLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELASAIVR 485
A+ +LA ++ D+A ++ I+ + +L + N +YK++A ++LRAV KH+ +LA AIV
Sbjct: 64 ALGRLANYNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQLAQAIVD 123
Query: 486 LGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQLAGLVVDAGTLPLLVLAFQEPE 656
GAL+ +V CLEDFD VKE AAWA+ YI +H+ +L+ VVDAG +PLLVL QEPE
Sbjct: 124 CGALDTLVICLEDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEPE 180
Score = 73.7 bits (173), Expect = 5e-13
Identities = 38/164 (23%), Positives = 83/164 (50%), Gaps = 2/164 (1%)
Frame = +3
Query: 171 VFVQTMAELATRSSNV-KCLESAGVLELLKPLLSDACSTIRQCAVVAIAKLAEHDLDIAR 347
+ ++++A S + + + AG + L ++ + + ++ + A++++++H +D+A
Sbjct: 186 IAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSKHSVDLAE 245
Query: 348 QLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELASAIVRLGALEHIVSCLEDF 527
++ I + L L + Y K++A L+R +AKH EL+ +V G + ++ C+
Sbjct: 246 MVVEAEIFPVVLTCLKDKDEYVKKNASTLIREIAKHTPELSQLVVNAGGVAAVIDCIGSC 305
Query: 528 DTQVKENAAWAVGYIGKHSEQLA-GLVVDAGTLPLLVLAFQEPE 656
+ +GY+ HSE LA +++ G L V +EPE
Sbjct: 306 KGNTRLPGIMMLGYVAAHSENLAMAVIISKGVPQLSVCLSEEPE 349
Score = 73.3 bits (172), Expect = 7e-13
Identities = 39/168 (23%), Positives = 88/168 (52%)
Frame = +3
Query: 153 YQKARLVFVQTMAELATRSSNVKCLESAGVLELLKPLLSDACSTIRQCAVVAIAKLAEHD 332
Y+KA ++ + + + + + + + G L+ L L D +++ A A+ +A H+
Sbjct: 99 YKKAAAFVLRAVGKHSPQLA--QAIVDCGALDTLVICLEDFDPGVKEAAAWALRYIARHN 156
Query: 333 LDIARQLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELASAIVRLGALEHIVS 512
++++ +++ G + + + + + + KR A L +AKH+ ELA +V GA+ H+
Sbjct: 157 AELSQAVVDAGAVPLLVLCIQEPEIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQ 216
Query: 513 CLEDFDTQVKENAAWAVGYIGKHSEQLAGLVVDAGTLPLLVLAFQEPE 656
+ + D ++K A+ + KHS LA +VV+A P+++ ++ +
Sbjct: 217 MILNPDAKLKHQILSALSQVSKHSVDLAEMVVEAEIFPVVLTCLKDKD 264
Score = 69.3 bits (162), Expect = 1e-11
Identities = 36/134 (26%), Positives = 74/134 (55%)
Frame = +3
Query: 234 AGVLELLKPLLSDACSTIRQCAVVAIAKLAEHDLDIARQLLNGGIITITLENLNKYNVYY 413
AG + LL + + +++ A A++ +A+H ++A+ +++ G + + + +
Sbjct: 166 AGAVPLLVLCIQEPEIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKL 225
Query: 414 KRSALYLLRAVAKHNEELASAIVRLGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQL 593
K L L V+KH+ +LA +V +++CL+D D VK+NA+ + I KH+ +L
Sbjct: 226 KHQILSALSQVSKHSVDLAEMVVEAEIFPVVLTCLKDKDEYVKKNASTLIREIAKHTPEL 285
Query: 594 AGLVVDAGTLPLLV 635
+ LVV+AG + ++
Sbjct: 286 SQLVVNAGGVAAVI 299
Score = 67.7 bits (158), Expect = 3e-11
Identities = 39/176 (22%), Positives = 89/176 (50%), Gaps = 2/176 (1%)
Frame = +3
Query: 135 QLVFETYQKARLVFVQTMAELATRSSNV-KCLESAGVLELLKPLLSDACSTIRQCAVVAI 311
Q++ K + + +++++ S ++ + + A + ++ L D +++ A I
Sbjct: 216 QMILNPDAKLKHQILSALSQVSKHSVDLAEMVVEAEIFPVVLTCLKDKDEYVKKNASTLI 275
Query: 312 AKLAEHDLDIARQLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELASAIVRLG 491
++A+H ++++ ++N G + ++ + + + +L VA H+E LA A++
Sbjct: 276 REIAKHTPELSQLVVNAGGVAAVIDCIGSCKGNTRLPGIMMLGYVAAHSENLAMAVIISK 335
Query: 492 ALEHIVSCL-EDFDTQVKENAAWAVGYIGKHSEQLAGLVVDAGTLPLLVLAFQEPE 656
+ + CL E+ + +K AAWA+G IG+H+ + A V TLP+L+ + E
Sbjct: 336 GVPQLSVCLSEEPEDHIKAAAAWALGQIGRHTPEHARAVAVTNTLPVLLSLYMSTE 391
>AL513128-1|CAH72207.1| 246|Homo sapiens sperm associated antigen 6
protein.
Length = 246
Score = 123 bits (296), Expect = 6e-28
Identities = 60/130 (46%), Positives = 90/130 (69%)
Frame = +3
Query: 237 GVLELLKPLLSDACSTIRQCAVVAIAKLAEHDLDIARQLLNGGIITITLENLNKYNVYYK 416
GV+ LL+ LL D TI+Q A +A+ +LA ++ D+A ++ I+ + +L + N +YK
Sbjct: 117 GVMSLLRTLLLDVVPTIQQTAALALGRLANYNDDLAEAVVKCDILPQLVYSLAEQNRFYK 176
Query: 417 RSALYLLRAVAKHNEELASAIVRLGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQLA 596
++A ++LRAV KH+ +LA AIV GAL+ +V CLEDFD VKE AAWA+ YI +H+ +L+
Sbjct: 177 KAAAFVLRAVGKHSPQLAQAIVDCGALDTLVICLEDFDPGVKEAAAWALRYIARHNAELS 236
Query: 597 GLVVDAGTLP 626
VVDAG +P
Sbjct: 237 QAVVDAGAVP 246
Score = 54.0 bits (124), Expect = 4e-07
Identities = 27/79 (34%), Positives = 47/79 (59%)
Frame = +3
Query: 414 KRSALYLLRAVAKHNEELASAIVRLGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQL 593
+++A L +A +N++LA A+V+ L +V L + + K+ AA+ + +GKHS QL
Sbjct: 134 QQTAALALGRLANYNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQL 193
Query: 594 AGLVVDAGTLPLLVLAFQE 650
A +VD G L LV+ ++
Sbjct: 194 AQAIVDCGALDTLVICLED 212
Score = 52.8 bits (121), Expect = 1e-06
Identities = 48/177 (27%), Positives = 80/177 (45%), Gaps = 2/177 (1%)
Frame = +3
Query: 126 RNIQLVFETYQKARLVFVQTMAELATRSSNVKCLESAGVLELLKPLLSDACSTIRQCAVV 305
R + VFE YQKAR FVQ +AELATR N++ L++AG P+ A S R
Sbjct: 4 RQVLQVFEQYQKARTQFVQMVAELATRPQNIETLQNAGEPGARTPVAPRALSPRRLRPAA 63
Query: 306 AIAKLAEHDLDIARQLLNGGIITITLENLNKYNVYYKRSA--LYLLRAVAKHNEELASAI 479
+L L + + T ++++ + + A + L + L +
Sbjct: 64 LPVEL----------LGSRSVGTGVRKSIHSFQRVFGGQAERVKLPDGCGRCALSLFPSS 113
Query: 480 VRLGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQLAGLVVDAGTLPLLVLAFQE 650
+ G + + + L D +++ AA A+G + +++ LA VV LP LV + E
Sbjct: 114 LHTGVMSLLRTLLLDVVPTIQQTAALALGRLANYNDDLAEAVVKCDILPQLVYSLAE 170
>AL158211-12|CAI15960.1| 246|Homo sapiens sperm associated antigen
6 protein.
Length = 246
Score = 123 bits (296), Expect = 6e-28
Identities = 60/130 (46%), Positives = 90/130 (69%)
Frame = +3
Query: 237 GVLELLKPLLSDACSTIRQCAVVAIAKLAEHDLDIARQLLNGGIITITLENLNKYNVYYK 416
GV+ LL+ LL D TI+Q A +A+ +LA ++ D+A ++ I+ + +L + N +YK
Sbjct: 117 GVMSLLRTLLLDVVPTIQQTAALALGRLANYNDDLAEAVVKCDILPQLVYSLAEQNRFYK 176
Query: 417 RSALYLLRAVAKHNEELASAIVRLGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQLA 596
++A ++LRAV KH+ +LA AIV GAL+ +V CLEDFD VKE AAWA+ YI +H+ +L+
Sbjct: 177 KAAAFVLRAVGKHSPQLAQAIVDCGALDTLVICLEDFDPGVKEAAAWALRYIARHNAELS 236
Query: 597 GLVVDAGTLP 626
VVDAG +P
Sbjct: 237 QAVVDAGAVP 246
Score = 54.0 bits (124), Expect = 4e-07
Identities = 27/79 (34%), Positives = 47/79 (59%)
Frame = +3
Query: 414 KRSALYLLRAVAKHNEELASAIVRLGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQL 593
+++A L +A +N++LA A+V+ L +V L + + K+ AA+ + +GKHS QL
Sbjct: 134 QQTAALALGRLANYNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQL 193
Query: 594 AGLVVDAGTLPLLVLAFQE 650
A +VD G L LV+ ++
Sbjct: 194 AQAIVDCGALDTLVICLED 212
Score = 52.8 bits (121), Expect = 1e-06
Identities = 48/177 (27%), Positives = 80/177 (45%), Gaps = 2/177 (1%)
Frame = +3
Query: 126 RNIQLVFETYQKARLVFVQTMAELATRSSNVKCLESAGVLELLKPLLSDACSTIRQCAVV 305
R + VFE YQKAR FVQ +AELATR N++ L++AG P+ A S R
Sbjct: 4 RQVLQVFEQYQKARTQFVQMVAELATRPQNIETLQNAGEPGARTPVAPRALSPRRLRPAA 63
Query: 306 AIAKLAEHDLDIARQLLNGGIITITLENLNKYNVYYKRSA--LYLLRAVAKHNEELASAI 479
+L L + + T ++++ + + A + L + L +
Sbjct: 64 LPVEL----------LGSRSVGTGVRKSIHSFQRVFGGQAERVKLPDGCGRCALSLFPSS 113
Query: 480 VRLGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQLAGLVVDAGTLPLLVLAFQE 650
+ G + + + L D +++ AA A+G + +++ LA VV LP LV + E
Sbjct: 114 LHTGVMSLLRTLLLDVVPTIQQTAALALGRLANYNDDLAEAVVKCDILPQLVYSLAE 170
>AL513128-2|CAH72208.1| 191|Homo sapiens sperm associated antigen 6
protein.
Length = 191
Score = 78.6 bits (185), Expect = 2e-14
Identities = 40/93 (43%), Positives = 61/93 (65%)
Frame = +3
Query: 126 RNIQLVFETYQKARLVFVQTMAELATRSSNVKCLESAGVLELLKPLLSDACSTIRQCAVV 305
R + VFE YQKAR FVQ +AELATR N++ L++AGV+ LL+ LL D TI+Q A +
Sbjct: 4 RQVLQVFEQYQKARTQFVQMVAELATRPQNIETLQNAGVMSLLRTLLLDVVPTIQQTAAL 63
Query: 306 AIAKLAEHDLDIARQLLNGGIITITLENLNKYN 404
A+ +LA ++ D+A ++ I+ + +L + N
Sbjct: 64 ALGRLANYNDDLAEAVVKCDILPQLVYSLAEQN 96
Score = 48.4 bits (110), Expect = 2e-05
Identities = 38/133 (28%), Positives = 65/133 (48%), Gaps = 14/133 (10%)
Frame = +3
Query: 300 VVAIAKLAEHDLDIARQLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELASAI 479
V +A+LA +I L N G++++ L +++A L +A +N++LA A+
Sbjct: 21 VQMVAELATRPQNI-ETLQNAGVMSLLRTLLLDVVPTIQQTAALALGRLANYNDDLAEAV 79
Query: 480 VRLGALEHIVS-------------CL-EDFDTQVKENAAWAVGYIGKHSEQLAGLVVDAG 617
V+ L +V CL E+ + +K AAWA+G IG+H+ + A V
Sbjct: 80 VKCDILPQLVYSLAEQNGVPQLSVCLSEEPEDHIKAAAAWALGQIGRHTPEHARAVAVTN 139
Query: 618 TLPLLVLAFQEPE 656
TLP+L+ + E
Sbjct: 140 TLPVLLSLYMSTE 152
>AL158211-13|CAI15961.1| 191|Homo sapiens sperm associated antigen
6 protein.
Length = 191
Score = 78.6 bits (185), Expect = 2e-14
Identities = 40/93 (43%), Positives = 61/93 (65%)
Frame = +3
Query: 126 RNIQLVFETYQKARLVFVQTMAELATRSSNVKCLESAGVLELLKPLLSDACSTIRQCAVV 305
R + VFE YQKAR FVQ +AELATR N++ L++AGV+ LL+ LL D TI+Q A +
Sbjct: 4 RQVLQVFEQYQKARTQFVQMVAELATRPQNIETLQNAGVMSLLRTLLLDVVPTIQQTAAL 63
Query: 306 AIAKLAEHDLDIARQLLNGGIITITLENLNKYN 404
A+ +LA ++ D+A ++ I+ + +L + N
Sbjct: 64 ALGRLANYNDDLAEAVVKCDILPQLVYSLAEQN 96
Score = 48.4 bits (110), Expect = 2e-05
Identities = 38/133 (28%), Positives = 65/133 (48%), Gaps = 14/133 (10%)
Frame = +3
Query: 300 VVAIAKLAEHDLDIARQLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELASAI 479
V +A+LA +I L N G++++ L +++A L +A +N++LA A+
Sbjct: 21 VQMVAELATRPQNI-ETLQNAGVMSLLRTLLLDVVPTIQQTAALALGRLANYNDDLAEAV 79
Query: 480 VRLGALEHIVS-------------CL-EDFDTQVKENAAWAVGYIGKHSEQLAGLVVDAG 617
V+ L +V CL E+ + +K AAWA+G IG+H+ + A V
Sbjct: 80 VKCDILPQLVYSLAEQNGVPQLSVCLSEEPEDHIKAAAAWALGQIGRHTPEHARAVAVTN 139
Query: 618 TLPLLVLAFQEPE 656
TLP+L+ + E
Sbjct: 140 TLPVLLSLYMSTE 152
>Y12394-1|CAA73026.1| 521|Homo sapiens SRP1-like protein protein.
Length = 521
Score = 41.9 bits (94), Expect = 0.002
Identities = 21/112 (18%), Positives = 52/112 (46%)
Frame = +3
Query: 300 VVAIAKLAEHDLDIARQLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELASAI 479
V A++ L + + + +++ G++ + L+ V + +AL + + +E +
Sbjct: 263 VWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVV 322
Query: 480 VRLGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQLAGLVVDAGTLPLLV 635
+ L H + L ++ + A W + I ++Q V+DAG +P+++
Sbjct: 323 LNCDVLSHFPNLLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMII 374
Score = 33.5 bits (73), Expect = 0.68
Identities = 28/114 (24%), Positives = 50/114 (43%), Gaps = 2/114 (1%)
Frame = +3
Query: 318 LAEHDLDIARQLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELA-SAIVRLGA 494
L + D+D + N + I L+N N + SA+ R + + +++ G
Sbjct: 57 LEDSDVDADFKAQNVTLEAI-LQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGI 115
Query: 495 LEHIVSCLE-DFDTQVKENAAWAVGYIGKHSEQLAGLVVDAGTLPLLVLAFQEP 653
L +V CLE D + ++ AAWA+ I + VV + +PL + + P
Sbjct: 116 LPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSP 169
>D89618-1|BAA20378.1| 521|Homo sapiens karyopherin alhph 3 protein.
Length = 521
Score = 41.9 bits (94), Expect = 0.002
Identities = 21/112 (18%), Positives = 52/112 (46%)
Frame = +3
Query: 300 VVAIAKLAEHDLDIARQLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELASAI 479
V A++ L + + + +++ G++ + L+ V + +AL + + +E +
Sbjct: 263 VWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVV 322
Query: 480 VRLGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQLAGLVVDAGTLPLLV 635
+ L H + L ++ + A W + I ++Q V+DAG +P+++
Sbjct: 323 LNCDVLSHFPNLLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMII 374
Score = 34.3 bits (75), Expect = 0.39
Identities = 28/114 (24%), Positives = 51/114 (44%), Gaps = 2/114 (1%)
Frame = +3
Query: 318 LAEHDLDIARQLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELA-SAIVRLGA 494
L + D+D + N + I L+N N + SA+ R + ++ +++ G
Sbjct: 57 LEDSDVDADFKAQNVTLEAI-LQNATSDNPVVQLSAVQAARKLLSSDQNPPIDDLIKSGI 115
Query: 495 LEHIVSCLE-DFDTQVKENAAWAVGYIGKHSEQLAGLVVDAGTLPLLVLAFQEP 653
L +V CLE D + ++ AAWA+ I + VV + +PL + + P
Sbjct: 116 LPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSP 169
>BC035090-1|AAH35090.1| 521|Homo sapiens karyopherin alpha 3
(importin alpha 4) protein.
Length = 521
Score = 41.9 bits (94), Expect = 0.002
Identities = 21/112 (18%), Positives = 52/112 (46%)
Frame = +3
Query: 300 VVAIAKLAEHDLDIARQLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELASAI 479
V A++ L + + + +++ G++ + L+ V + +AL + + +E +
Sbjct: 263 VWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVV 322
Query: 480 VRLGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQLAGLVVDAGTLPLLV 635
+ L H + L ++ + A W + I ++Q V+DAG +P+++
Sbjct: 323 LNCDVLSHFQNLLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMII 374
Score = 31.9 bits (69), Expect = 2.1
Identities = 27/114 (23%), Positives = 50/114 (43%), Gaps = 2/114 (1%)
Frame = +3
Query: 318 LAEHDLDIARQLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELA-SAIVRLGA 494
L + D+D + N + I L+N N + SA+ R + + +++ G
Sbjct: 57 LEDSDVDADFKAQNVTLEAI-LQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGI 115
Query: 495 LEHIVSCLE-DFDTQVKENAAWAVGYIGKHSEQLAGLVVDAGTLPLLVLAFQEP 653
L +V CLE D + ++ AAWA+ I + +V + +PL + + P
Sbjct: 116 LPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQDIVQSNAVPLFLRLLRSP 169
>BC024202-1|AAH24202.1| 521|Homo sapiens karyopherin alpha 3
(importin alpha 4) protein.
Length = 521
Score = 41.9 bits (94), Expect = 0.002
Identities = 21/112 (18%), Positives = 52/112 (46%)
Frame = +3
Query: 300 VVAIAKLAEHDLDIARQLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELASAI 479
V A++ L + + + +++ G++ + L+ V + +AL + + +E +
Sbjct: 263 VWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVV 322
Query: 480 VRLGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQLAGLVVDAGTLPLLV 635
+ L H + L ++ + A W + I ++Q V+DAG +P+++
Sbjct: 323 LNCDVLSHFPNLLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMII 374
Score = 33.5 bits (73), Expect = 0.68
Identities = 28/114 (24%), Positives = 50/114 (43%), Gaps = 2/114 (1%)
Frame = +3
Query: 318 LAEHDLDIARQLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELA-SAIVRLGA 494
L + D+D + N + I L+N N + SA+ R + + +++ G
Sbjct: 57 LEDSDVDADFKAQNVTLEAI-LQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGI 115
Query: 495 LEHIVSCLE-DFDTQVKENAAWAVGYIGKHSEQLAGLVVDAGTLPLLVLAFQEP 653
L +V CLE D + ++ AAWA+ I + VV + +PL + + P
Sbjct: 116 LPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSP 169
>BC017355-1|AAH17355.1| 521|Homo sapiens karyopherin alpha 3
(importin alpha 4) protein.
Length = 521
Score = 41.9 bits (94), Expect = 0.002
Identities = 21/112 (18%), Positives = 52/112 (46%)
Frame = +3
Query: 300 VVAIAKLAEHDLDIARQLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELASAI 479
V A++ L + + + +++ G++ + L+ V + +AL + + +E +
Sbjct: 263 VWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVV 322
Query: 480 VRLGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQLAGLVVDAGTLPLLV 635
+ L H + L ++ + A W + I ++Q V+DAG +P+++
Sbjct: 323 LNCDVLSHFPNLLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMII 374
Score = 33.5 bits (73), Expect = 0.68
Identities = 28/114 (24%), Positives = 50/114 (43%), Gaps = 2/114 (1%)
Frame = +3
Query: 318 LAEHDLDIARQLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELA-SAIVRLGA 494
L + D+D + N + I L+N N + SA+ R + + +++ G
Sbjct: 57 LEDSDVDADFKAQNVTLEAI-LQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGI 115
Query: 495 LEHIVSCLE-DFDTQVKENAAWAVGYIGKHSEQLAGLVVDAGTLPLLVLAFQEP 653
L +V CLE D + ++ AAWA+ I + VV + +PL + + P
Sbjct: 116 LPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSP 169
>AL136301-1|CAH71145.1| 521|Homo sapiens karyopherin alpha 3
(importin alpha 4) protein.
Length = 521
Score = 41.9 bits (94), Expect = 0.002
Identities = 21/112 (18%), Positives = 52/112 (46%)
Frame = +3
Query: 300 VVAIAKLAEHDLDIARQLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELASAI 479
V A++ L + + + +++ G++ + L+ V + +AL + + +E +
Sbjct: 263 VWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVV 322
Query: 480 VRLGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQLAGLVVDAGTLPLLV 635
+ L H + L ++ + A W + I ++Q V+DAG +P+++
Sbjct: 323 LNCDVLSHFPNLLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMII 374
Score = 33.5 bits (73), Expect = 0.68
Identities = 28/114 (24%), Positives = 50/114 (43%), Gaps = 2/114 (1%)
Frame = +3
Query: 318 LAEHDLDIARQLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELA-SAIVRLGA 494
L + D+D + N + I L+N N + SA+ R + + +++ G
Sbjct: 57 LEDSDVDADFKAQNVTLEAI-LQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGI 115
Query: 495 LEHIVSCLE-DFDTQVKENAAWAVGYIGKHSEQLAGLVVDAGTLPLLVLAFQEP 653
L +V CLE D + ++ AAWA+ I + VV + +PL + + P
Sbjct: 116 LPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSP 169
>AL135901-3|CAI40716.1| 521|Homo sapiens karyopherin alpha 3
(importin alpha 4) protein.
Length = 521
Score = 41.9 bits (94), Expect = 0.002
Identities = 21/112 (18%), Positives = 52/112 (46%)
Frame = +3
Query: 300 VVAIAKLAEHDLDIARQLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELASAI 479
V A++ L + + + +++ G++ + L+ V + +AL + + +E +
Sbjct: 263 VWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVV 322
Query: 480 VRLGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQLAGLVVDAGTLPLLV 635
+ L H + L ++ + A W + I ++Q V+DAG +P+++
Sbjct: 323 LNCDVLSHFPNLLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMII 374
Score = 33.5 bits (73), Expect = 0.68
Identities = 28/114 (24%), Positives = 50/114 (43%), Gaps = 2/114 (1%)
Frame = +3
Query: 318 LAEHDLDIARQLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELA-SAIVRLGA 494
L + D+D + N + I L+N N + SA+ R + + +++ G
Sbjct: 57 LEDSDVDADFKAQNVTLEAI-LQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGI 115
Query: 495 LEHIVSCLE-DFDTQVKENAAWAVGYIGKHSEQLAGLVVDAGTLPLLVLAFQEP 653
L +V CLE D + ++ AAWA+ I + VV + +PL + + P
Sbjct: 116 LPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSP 169
>AK223480-1|BAD97200.1| 521|Homo sapiens karyopherin alpha 3
variant protein.
Length = 521
Score = 41.9 bits (94), Expect = 0.002
Identities = 21/112 (18%), Positives = 52/112 (46%)
Frame = +3
Query: 300 VVAIAKLAEHDLDIARQLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELASAI 479
V A++ L + + + +++ G++ + L+ V + +AL + + +E +
Sbjct: 263 VWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVV 322
Query: 480 VRLGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQLAGLVVDAGTLPLLV 635
+ L H + L ++ + A W + I ++Q V+DAG +P+++
Sbjct: 323 LNCDVLSHFPNLLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMII 374
Score = 33.5 bits (73), Expect = 0.68
Identities = 28/114 (24%), Positives = 50/114 (43%), Gaps = 2/114 (1%)
Frame = +3
Query: 318 LAEHDLDIARQLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELA-SAIVRLGA 494
L + D+D + N + I L+N N + SA+ R + + +++ G
Sbjct: 57 LEDSDVDADFKAQNVTLEAI-LQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGI 115
Query: 495 LEHIVSCLE-DFDTQVKENAAWAVGYIGKHSEQLAGLVVDAGTLPLLVLAFQEP 653
L +V CLE D + ++ AAWA+ I + VV + +PL + + P
Sbjct: 116 LPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSP 169
>AF034756-1|AAB87693.1| 521|Homo sapiens importin-alpha homolog
protein.
Length = 521
Score = 41.9 bits (94), Expect = 0.002
Identities = 21/112 (18%), Positives = 52/112 (46%)
Frame = +3
Query: 300 VVAIAKLAEHDLDIARQLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELASAI 479
V A++ L + + + +++ G++ + L+ V + +AL + + +E +
Sbjct: 263 VWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVV 322
Query: 480 VRLGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQLAGLVVDAGTLPLLV 635
+ L H + L ++ + A W + I ++Q V+DAG +P+++
Sbjct: 323 LNCDVLSHFPNLLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMII 374
>AF005263-1|AAQ13404.1| 521|Homo sapiens importin alpha-3 subunit
protein.
Length = 521
Score = 41.9 bits (94), Expect = 0.002
Identities = 21/112 (18%), Positives = 52/112 (46%)
Frame = +3
Query: 300 VVAIAKLAEHDLDIARQLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELASAI 479
V A++ L + + + +++ G++ + L+ V + +AL + + +E +
Sbjct: 263 VWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVV 322
Query: 480 VRLGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQLAGLVVDAGTLPLLV 635
+ L H + L ++ + A W + I ++Q V+DAG +P+++
Sbjct: 323 LNCDVLSHFPNLLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMII 374
Score = 33.5 bits (73), Expect = 0.68
Identities = 28/114 (24%), Positives = 50/114 (43%), Gaps = 2/114 (1%)
Frame = +3
Query: 318 LAEHDLDIARQLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELA-SAIVRLGA 494
L + D+D + N + I L+N N + SA+ R + + +++ G
Sbjct: 57 LEDSDVDADFKAQNVTLEAI-LQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGI 115
Query: 495 LEHIVSCLE-DFDTQVKENAAWAVGYIGKHSEQLAGLVVDAGTLPLLVLAFQEP 653
L +V CLE D + ++ AAWA+ I + VV + +PL + + P
Sbjct: 116 LPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSP 169
>Y12393-1|CAA73025.1| 281|Homo sapiens SRP1-like protein protein.
Length = 281
Score = 39.5 bits (88), Expect = 0.010
Identities = 22/112 (19%), Positives = 52/112 (46%)
Frame = +3
Query: 300 VVAIAKLAEHDLDIARQLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELASAI 479
V A++ L + + + +++ GI+ + L+ V + +AL + + +E +
Sbjct: 23 VWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVV 82
Query: 480 VRLGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQLAGLVVDAGTLPLLV 635
+ AL H + L ++ + A W + I ++Q V+DA +P+++
Sbjct: 83 LNCDALSHFPALLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMII 134
>U93240-1|AAC25605.1| 521|Homo sapiens importin alpha 3 protein.
Length = 521
Score = 39.5 bits (88), Expect = 0.010
Identities = 22/112 (19%), Positives = 52/112 (46%)
Frame = +3
Query: 300 VVAIAKLAEHDLDIARQLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELASAI 479
V A++ L + + + +++ GI+ + L+ V + +AL + + +E +
Sbjct: 263 VWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVV 322
Query: 480 VRLGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQLAGLVVDAGTLPLLV 635
+ AL H + L ++ + A W + I ++Q V+DA +P+++
Sbjct: 323 LNCDALSHFPALLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMII 374
Score = 32.7 bits (71), Expect = 1.2
Identities = 26/112 (23%), Positives = 51/112 (45%), Gaps = 2/112 (1%)
Frame = +3
Query: 324 EHDLDIARQLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELA-SAIVRLGALE 500
+ D+D ++ N + I ++N + N + SA+ R + + +++ G L
Sbjct: 59 DSDIDGDYRVQNTSLEAI-VQNASSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILP 117
Query: 501 HIVSCLE-DFDTQVKENAAWAVGYIGKHSEQLAGLVVDAGTLPLLVLAFQEP 653
+V CLE D + ++ AAWA+ I + + VV + +PL + P
Sbjct: 118 ILVHCLERDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSP 169
>BC034493-1|AAH34493.1| 521|Homo sapiens karyopherin alpha 4
(importin alpha 3) protein.
Length = 521
Score = 39.5 bits (88), Expect = 0.010
Identities = 22/112 (19%), Positives = 52/112 (46%)
Frame = +3
Query: 300 VVAIAKLAEHDLDIARQLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELASAI 479
V A++ L + + + +++ GI+ + L+ V + +AL + + +E +
Sbjct: 263 VWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVV 322
Query: 480 VRLGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQLAGLVVDAGTLPLLV 635
+ AL H + L ++ + A W + I ++Q V+DA +P+++
Sbjct: 323 LNCDALSHFPALLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMII 374
Score = 32.7 bits (71), Expect = 1.2
Identities = 26/112 (23%), Positives = 51/112 (45%), Gaps = 2/112 (1%)
Frame = +3
Query: 324 EHDLDIARQLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELA-SAIVRLGALE 500
+ D+D ++ N + I ++N + N + SA+ R + + +++ G L
Sbjct: 59 DSDIDGDYRVQNTSLEAI-VQNASSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILP 117
Query: 501 HIVSCLE-DFDTQVKENAAWAVGYIGKHSEQLAGLVVDAGTLPLLVLAFQEP 653
+V CLE D + ++ AAWA+ I + + VV + +PL + P
Sbjct: 118 ILVHCLERDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSP 169
>BC028691-1|AAH28691.1| 521|Homo sapiens karyopherin alpha 4
(importin alpha 3) protein.
Length = 521
Score = 39.5 bits (88), Expect = 0.010
Identities = 22/112 (19%), Positives = 52/112 (46%)
Frame = +3
Query: 300 VVAIAKLAEHDLDIARQLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELASAI 479
V A++ L + + + +++ GI+ + L+ V + +AL + + +E +
Sbjct: 263 VWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVV 322
Query: 480 VRLGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQLAGLVVDAGTLPLLV 635
+ AL H + L ++ + A W + I ++Q V+DA +P+++
Sbjct: 323 LNCDALSHFPALLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMII 374
Score = 32.7 bits (71), Expect = 1.2
Identities = 26/112 (23%), Positives = 51/112 (45%), Gaps = 2/112 (1%)
Frame = +3
Query: 324 EHDLDIARQLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELA-SAIVRLGALE 500
+ D+D ++ N + I ++N + N + SA+ R + + +++ G L
Sbjct: 59 DSDIDGDYRVQNTSLEAI-VQNASSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILP 117
Query: 501 HIVSCLE-DFDTQVKENAAWAVGYIGKHSEQLAGLVVDAGTLPLLVLAFQEP 653
+V CLE D + ++ AAWA+ I + + VV + +PL + P
Sbjct: 118 ILVHCLERDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSP 169
>AB002533-1|BAA19546.1| 521|Homo sapiens Qip1 protein.
Length = 521
Score = 39.5 bits (88), Expect = 0.010
Identities = 22/112 (19%), Positives = 52/112 (46%)
Frame = +3
Query: 300 VVAIAKLAEHDLDIARQLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELASAI 479
V A++ L + + + +++ GI+ + L+ V + +AL + + +E +
Sbjct: 263 VWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVV 322
Query: 480 VRLGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQLAGLVVDAGTLPLLV 635
+ AL H + L ++ + A W + I ++Q V+DA +P+++
Sbjct: 323 LNCDALSHFPALLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMII 374
Score = 32.7 bits (71), Expect = 1.2
Identities = 26/112 (23%), Positives = 51/112 (45%), Gaps = 2/112 (1%)
Frame = +3
Query: 324 EHDLDIARQLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELA-SAIVRLGALE 500
+ D+D ++ N + I ++N + N + SA+ R + + +++ G L
Sbjct: 59 DSDIDGDYRVQNTSLEAI-VQNASSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILP 117
Query: 501 HIVSCLE-DFDTQVKENAAWAVGYIGKHSEQLAGLVVDAGTLPLLVLAFQEP 653
+V CLE D + ++ AAWA+ I + + VV + +PL + P
Sbjct: 118 ILVHCLERDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSP 169
>U28386-1|AAA69957.1| 529|Homo sapiens hSRP1alpha protein.
Length = 529
Score = 36.3 bits (80), Expect = 0.096
Identities = 22/71 (30%), Positives = 31/71 (43%), Gaps = 1/71 (1%)
Frame = +3
Query: 429 YLLRAVAKHNEELASAIVRLGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQLAGLVV 608
+ L +A E A+V GA+ +S L + E A WA+G I LV+
Sbjct: 142 WALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSVFRDLVI 201
Query: 609 DAGTL-PLLVL 638
G + PLL L
Sbjct: 202 KYGAVDPLLAL 212
Score = 35.9 bits (79), Expect = 0.13
Identities = 31/148 (20%), Positives = 59/148 (39%), Gaps = 5/148 (3%)
Frame = +3
Query: 207 SSNVKCLESAGVLELLKPLLSDACSTIRQCAVVAIAKLAE-----HDLDIARQLLNGGII 371
S K + G + LL+ + I + AV A+ +A DL I ++ +
Sbjct: 152 SEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSVFRDLVIKYGAVDPLLA 211
Query: 372 TITLENLNKYNVYYKRSALYLLRAVAKHNEELASAIVRLGALEHIVSCLEDFDTQVKENA 551
+ + +++ Y R+ + L + ++ L +V L D +V +
Sbjct: 212 LLAVPDMSSLACGYLRNLTWTLSNLCRNKNPAPPIDAVEQILPTLVRLLHHDDPEVLADT 271
Query: 552 AWAVGYIGKHSEQLAGLVVDAGTLPLLV 635
WA+ Y+ + G+VV G +P LV
Sbjct: 272 CWAISYLTDGPNERIGMVVKTGVVPQLV 299
Score = 33.1 bits (72), Expect = 0.90
Identities = 22/93 (23%), Positives = 41/93 (44%), Gaps = 2/93 (2%)
Frame = +3
Query: 381 LENLNKYNVYYKRSALYLLRAV-AKHNEELASAIVRLGALEHIVSCLEDFD-TQVKENAA 554
++ +N NV + A R + ++ + I+R G + VS L D + ++ +A
Sbjct: 82 VKGINSSNVENQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGRTDCSPIQFESA 141
Query: 555 WAVGYIGKHSEQLAGLVVDAGTLPLLVLAFQEP 653
WA+ I + + VVD G +P + P
Sbjct: 142 WALTNIASGTSEQTKAVVDGGAIPAFISLLASP 174
Score = 31.9 bits (69), Expect = 2.1
Identities = 23/110 (20%), Positives = 46/110 (41%)
Frame = +3
Query: 306 AIAKLAEHDLDIARQLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELASAIVR 485
AI+ L + + ++ G++ ++ L + AL + + +E ++
Sbjct: 274 AISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVTPALRAIGNIVTGTDEQTQVVID 333
Query: 486 LGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQLAGLVVDAGTLPLLV 635
GAL S L + T +++ A W + I + VV+ G +P LV
Sbjct: 334 AGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLV 383
>U09559-1|AAA65700.1| 529|Homo sapiens Rch1 protein.
Length = 529
Score = 36.3 bits (80), Expect = 0.096
Identities = 22/71 (30%), Positives = 31/71 (43%), Gaps = 1/71 (1%)
Frame = +3
Query: 429 YLLRAVAKHNEELASAIVRLGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQLAGLVV 608
+ L +A E A+V GA+ +S L + E A WA+G I LV+
Sbjct: 142 WALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSVFRDLVI 201
Query: 609 DAGTL-PLLVL 638
G + PLL L
Sbjct: 202 KYGAVDPLLAL 212
Score = 35.9 bits (79), Expect = 0.13
Identities = 31/148 (20%), Positives = 59/148 (39%), Gaps = 5/148 (3%)
Frame = +3
Query: 207 SSNVKCLESAGVLELLKPLLSDACSTIRQCAVVAIAKLAE-----HDLDIARQLLNGGII 371
S K + G + LL+ + I + AV A+ +A DL I ++ +
Sbjct: 152 SEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSVFRDLVIKYGAVDPLLA 211
Query: 372 TITLENLNKYNVYYKRSALYLLRAVAKHNEELASAIVRLGALEHIVSCLEDFDTQVKENA 551
+ + +++ Y R+ + L + ++ L +V L D +V +
Sbjct: 212 LLAVPDMSSLACGYLRNLTWTLSNLCRNKNPAPPIDAVEQILPTLVRLLHHDDPEVLADT 271
Query: 552 AWAVGYIGKHSEQLAGLVVDAGTLPLLV 635
WA+ Y+ + G+VV G +P LV
Sbjct: 272 CWAISYLTDGPNERIGMVVKTGVVPQLV 299
Score = 33.1 bits (72), Expect = 0.90
Identities = 22/93 (23%), Positives = 41/93 (44%), Gaps = 2/93 (2%)
Frame = +3
Query: 381 LENLNKYNVYYKRSALYLLRAV-AKHNEELASAIVRLGALEHIVSCLEDFD-TQVKENAA 554
++ +N NV + A R + ++ + I+R G + VS L D + ++ +A
Sbjct: 82 VKGINSSNVENQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGRTDCSPIQFESA 141
Query: 555 WAVGYIGKHSEQLAGLVVDAGTLPLLVLAFQEP 653
WA+ I + + VVD G +P + P
Sbjct: 142 WALTNIASGTSEQTKAVVDGGAIPAFISLLASP 174
Score = 31.9 bits (69), Expect = 2.1
Identities = 23/110 (20%), Positives = 46/110 (41%)
Frame = +3
Query: 306 AIAKLAEHDLDIARQLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELASAIVR 485
AI+ L + + ++ G++ ++ L + AL + + +E ++
Sbjct: 274 AISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVTPALRAIGNIVTGTDEQTQVVID 333
Query: 486 LGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQLAGLVVDAGTLPLLV 635
GAL S L + T +++ A W + I + VV+ G +P LV
Sbjct: 334 AGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLV 383
>BC053343-1|AAH53343.1| 529|Homo sapiens karyopherin alpha 2 (RAG
cohort 1, importin alpha 1) protein.
Length = 529
Score = 36.3 bits (80), Expect = 0.096
Identities = 22/71 (30%), Positives = 31/71 (43%), Gaps = 1/71 (1%)
Frame = +3
Query: 429 YLLRAVAKHNEELASAIVRLGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQLAGLVV 608
+ L +A E A+V GA+ +S L + E A WA+G I LV+
Sbjct: 142 WALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSVFRDLVI 201
Query: 609 DAGTL-PLLVL 638
G + PLL L
Sbjct: 202 KYGAVDPLLAL 212
Score = 35.5 bits (78), Expect = 0.17
Identities = 31/148 (20%), Positives = 58/148 (39%), Gaps = 5/148 (3%)
Frame = +3
Query: 207 SSNVKCLESAGVLELLKPLLSDACSTIRQCAVVAIAKLAE-----HDLDIARQLLNGGII 371
S K + G + LL+ + I + AV A+ +A DL I ++ +
Sbjct: 152 SEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSVFRDLVIKYGAVDPLLA 211
Query: 372 TITLENLNKYNVYYKRSALYLLRAVAKHNEELASAIVRLGALEHIVSCLEDFDTQVKENA 551
+ + ++ Y R+ + L + ++ L +V L D +V +
Sbjct: 212 LLAVPEMSSLACGYLRNLTWTLSNLCRNKNPAPPIDAVEQILPTLVRLLHHDDPEVLADT 271
Query: 552 AWAVGYIGKHSEQLAGLVVDAGTLPLLV 635
WA+ Y+ + G+VV G +P LV
Sbjct: 272 CWAISYLTDGPNERIGMVVKTGVVPQLV 299
Score = 33.1 bits (72), Expect = 0.90
Identities = 22/93 (23%), Positives = 41/93 (44%), Gaps = 2/93 (2%)
Frame = +3
Query: 381 LENLNKYNVYYKRSALYLLRAV-AKHNEELASAIVRLGALEHIVSCLEDFD-TQVKENAA 554
++ +N NV + A R + ++ + I+R G + VS L D + ++ +A
Sbjct: 82 VKGINSSNVENQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGRTDCSPIQFESA 141
Query: 555 WAVGYIGKHSEQLAGLVVDAGTLPLLVLAFQEP 653
WA+ I + + VVD G +P + P
Sbjct: 142 WALTNIASGTSEQTKAVVDGGAIPAFISLLASP 174
Score = 31.9 bits (69), Expect = 2.1
Identities = 23/110 (20%), Positives = 46/110 (41%)
Frame = +3
Query: 306 AIAKLAEHDLDIARQLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELASAIVR 485
AI+ L + + ++ G++ ++ L + AL + + +E ++
Sbjct: 274 AISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVTPALRAIGNIVTGTDEQTQVVID 333
Query: 486 LGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQLAGLVVDAGTLPLLV 635
GAL S L + T +++ A W + I + VV+ G +P LV
Sbjct: 334 AGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLV 383
Score = 30.7 bits (66), Expect = 4.8
Identities = 23/117 (19%), Positives = 52/117 (44%)
Frame = +3
Query: 276 CSTIRQCAVVAIAKLAEHDLDIARQLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKH 455
CS I+ + A+ +A + + +++GG I + L + + A++ L +A
Sbjct: 133 CSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGD 192
Query: 456 NEELASAIVRLGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQLAGLVVDAGTLP 626
+++ GA++ +++ L V E ++ A GY+ + L+ L + P
Sbjct: 193 GSVFRDLVIKYGAVDPLLALL-----AVPEMSSLACGYLRNLTWTLSNLCRNKNPAP 244
>AJ303086-1|CAC83080.1| 529|Homo sapiens karyopherin alpha 2
protein.
Length = 529
Score = 36.3 bits (80), Expect = 0.096
Identities = 22/71 (30%), Positives = 31/71 (43%), Gaps = 1/71 (1%)
Frame = +3
Query: 429 YLLRAVAKHNEELASAIVRLGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQLAGLVV 608
+ L +A E A+V GA+ +S L + E A WA+G I LV+
Sbjct: 142 WALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSVFRDLVI 201
Query: 609 DAGTL-PLLVL 638
G + PLL L
Sbjct: 202 KYGAVDPLLAL 212
Score = 35.9 bits (79), Expect = 0.13
Identities = 31/148 (20%), Positives = 59/148 (39%), Gaps = 5/148 (3%)
Frame = +3
Query: 207 SSNVKCLESAGVLELLKPLLSDACSTIRQCAVVAIAKLAE-----HDLDIARQLLNGGII 371
S K + G + LL+ + I + AV A+ +A DL I ++ +
Sbjct: 152 SEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSVFRDLVIKYGAVDPLLA 211
Query: 372 TITLENLNKYNVYYKRSALYLLRAVAKHNEELASAIVRLGALEHIVSCLEDFDTQVKENA 551
+ + +++ Y R+ + L + ++ L +V L D +V +
Sbjct: 212 LLAVPDMSSLACGYLRNLTWTLSNLCRNKNPAPPIDAVEQILPTLVRLLHHDDPEVLADT 271
Query: 552 AWAVGYIGKHSEQLAGLVVDAGTLPLLV 635
WA+ Y+ + G+VV G +P LV
Sbjct: 272 CWAISYLTDGPNERIGMVVKTGVVPQLV 299
Score = 33.1 bits (72), Expect = 0.90
Identities = 22/93 (23%), Positives = 41/93 (44%), Gaps = 2/93 (2%)
Frame = +3
Query: 381 LENLNKYNVYYKRSALYLLRAV-AKHNEELASAIVRLGALEHIVSCLEDFD-TQVKENAA 554
++ +N NV + A R + ++ + I+R G + VS L D + ++ +A
Sbjct: 82 VKGINSSNVENQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGRTDCSPIQFESA 141
Query: 555 WAVGYIGKHSEQLAGLVVDAGTLPLLVLAFQEP 653
WA+ I + + VVD G +P + P
Sbjct: 142 WALTNIASGTSEQTKAVVDGGAIPAFISLLASP 174
Score = 31.9 bits (69), Expect = 2.1
Identities = 23/110 (20%), Positives = 46/110 (41%)
Frame = +3
Query: 306 AIAKLAEHDLDIARQLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELASAIVR 485
AI+ L + + ++ G++ ++ L + AL + + +E ++
Sbjct: 274 AISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVTPALRAIGNIVTGTDEQTQVVID 333
Query: 486 LGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQLAGLVVDAGTLPLLV 635
GAL S L + T +++ A W + I + VV+ G +P LV
Sbjct: 334 AGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLV 383
>BT006665-1|AAP35311.1| 529|Homo sapiens karyopherin alpha 2 (RAG
cohort 1, importin alpha 1) protein.
Length = 529
Score = 35.5 bits (78), Expect = 0.17
Identities = 31/148 (20%), Positives = 59/148 (39%), Gaps = 5/148 (3%)
Frame = +3
Query: 207 SSNVKCLESAGVLELLKPLLSDACSTIRQCAVVAIAKLAE-----HDLDIARQLLNGGII 371
S K + G + LL+ + I + AV A+ +A DL I ++ +
Sbjct: 152 SEQTKVVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSVFRDLVIKYGAVDPLLA 211
Query: 372 TITLENLNKYNVYYKRSALYLLRAVAKHNEELASAIVRLGALEHIVSCLEDFDTQVKENA 551
+ + +++ Y R+ + L + ++ L +V L D +V +
Sbjct: 212 LLAVPDMSSLACGYLRNLTWTLSNLCRNKNPAPPIDAVEQILPTLVRLLHHDDPEVLADT 271
Query: 552 AWAVGYIGKHSEQLAGLVVDAGTLPLLV 635
WA+ Y+ + G+VV G +P LV
Sbjct: 272 CWAISYLTDGPNERIGMVVKTGVVPQLV 299
Score = 34.7 bits (76), Expect = 0.29
Identities = 21/71 (29%), Positives = 30/71 (42%), Gaps = 1/71 (1%)
Frame = +3
Query: 429 YLLRAVAKHNEELASAIVRLGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQLAGLVV 608
+ L +A E +V GA+ +S L + E A WA+G I LV+
Sbjct: 142 WALTNIASGTSEQTKVVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSVFRDLVI 201
Query: 609 DAGTL-PLLVL 638
G + PLL L
Sbjct: 202 KYGAVDPLLAL 212
Score = 33.9 bits (74), Expect = 0.51
Identities = 22/93 (23%), Positives = 42/93 (45%), Gaps = 2/93 (2%)
Frame = +3
Query: 381 LENLNKYNVYYKRSALYLLRAV-AKHNEELASAIVRLGALEHIVSCLEDFD-TQVKENAA 554
++ +N NV + A R + ++ + I+R G + VS L D + ++ +A
Sbjct: 82 VKGINSSNVENQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGRTDCSPIQFESA 141
Query: 555 WAVGYIGKHSEQLAGLVVDAGTLPLLVLAFQEP 653
WA+ I + + +VVD G +P + P
Sbjct: 142 WALTNIASGTSEQTKVVVDGGAIPAFISLLASP 174
Score = 31.9 bits (69), Expect = 2.1
Identities = 23/110 (20%), Positives = 46/110 (41%)
Frame = +3
Query: 306 AIAKLAEHDLDIARQLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELASAIVR 485
AI+ L + + ++ G++ ++ L + AL + + +E ++
Sbjct: 274 AISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVTPALRAIGNIVTGTDEQTQVVID 333
Query: 486 LGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQLAGLVVDAGTLPLLV 635
GAL S L + T +++ A W + I + VV+ G +P LV
Sbjct: 334 AGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLV 383
>BC005978-1|AAH05978.1| 529|Homo sapiens karyopherin alpha 2 (RAG
cohort 1, importin alpha 1) protein.
Length = 529
Score = 35.5 bits (78), Expect = 0.17
Identities = 31/148 (20%), Positives = 59/148 (39%), Gaps = 5/148 (3%)
Frame = +3
Query: 207 SSNVKCLESAGVLELLKPLLSDACSTIRQCAVVAIAKLAE-----HDLDIARQLLNGGII 371
S K + G + LL+ + I + AV A+ +A DL I ++ +
Sbjct: 152 SEQTKVVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSVFRDLVIKYGAVDPLLA 211
Query: 372 TITLENLNKYNVYYKRSALYLLRAVAKHNEELASAIVRLGALEHIVSCLEDFDTQVKENA 551
+ + +++ Y R+ + L + ++ L +V L D +V +
Sbjct: 212 LLAVPDMSSLACGYLRNLTWTLSNLCRNKNPAPPIDAVEQILPTLVRLLHHDDPEVLADT 271
Query: 552 AWAVGYIGKHSEQLAGLVVDAGTLPLLV 635
WA+ Y+ + G+VV G +P LV
Sbjct: 272 CWAISYLTDGPNERIGMVVKTGVVPQLV 299
Score = 34.7 bits (76), Expect = 0.29
Identities = 21/71 (29%), Positives = 30/71 (42%), Gaps = 1/71 (1%)
Frame = +3
Query: 429 YLLRAVAKHNEELASAIVRLGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQLAGLVV 608
+ L +A E +V GA+ +S L + E A WA+G I LV+
Sbjct: 142 WALTNIASGTSEQTKVVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSVFRDLVI 201
Query: 609 DAGTL-PLLVL 638
G + PLL L
Sbjct: 202 KYGAVDPLLAL 212
Score = 33.9 bits (74), Expect = 0.51
Identities = 22/93 (23%), Positives = 42/93 (45%), Gaps = 2/93 (2%)
Frame = +3
Query: 381 LENLNKYNVYYKRSALYLLRAV-AKHNEELASAIVRLGALEHIVSCLEDFD-TQVKENAA 554
++ +N NV + A R + ++ + I+R G + VS L D + ++ +A
Sbjct: 82 VKGINSSNVENQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGRTDCSPIQFESA 141
Query: 555 WAVGYIGKHSEQLAGLVVDAGTLPLLVLAFQEP 653
WA+ I + + +VVD G +P + P
Sbjct: 142 WALTNIASGTSEQTKVVVDGGAIPAFISLLASP 174
Score = 31.9 bits (69), Expect = 2.1
Identities = 23/110 (20%), Positives = 46/110 (41%)
Frame = +3
Query: 306 AIAKLAEHDLDIARQLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELASAIVR 485
AI+ L + + ++ G++ ++ L + AL + + +E ++
Sbjct: 274 AISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVTPALRAIGNIVTGTDEQTQVVID 333
Query: 486 LGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQLAGLVVDAGTLPLLV 635
GAL S L + T +++ A W + I + VV+ G +P LV
Sbjct: 334 AGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLV 383
>S75295-1|AAC60648.1| 538|Homo sapiens nucleoprotein interactor 1
protein.
Length = 538
Score = 35.1 bits (77), Expect = 0.22
Identities = 28/138 (20%), Positives = 57/138 (41%)
Frame = +3
Query: 243 LELLKPLLSDACSTIRQCAVVAIAKLAEHDLDIARQLLNGGIITITLENLNKYNVYYKRS 422
L +L LL + + + A A++ L++ D + +++ G+ +E L +
Sbjct: 256 LNVLSWLLFVSDTDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHNDYKVVSP 315
Query: 423 ALYLLRAVAKHNEELASAIVRLGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQLAGL 602
AL + + ++ I+ AL+ ++ L +K+ A W + I +
Sbjct: 316 ALRAVGNIVTGDDIQTQVILNCSALQSLLHLLSSPKESIKKEACWTISNITAGNRAQIQT 375
Query: 603 VVDAGTLPLLVLAFQEPE 656
V+DA P L+ Q E
Sbjct: 376 VIDANIFPALISILQTAE 393
Score = 33.9 bits (74), Expect = 0.51
Identities = 30/136 (22%), Positives = 57/136 (41%), Gaps = 3/136 (2%)
Frame = +3
Query: 207 SSNVKCLESAGVLELLKPLLSDACSTIRQCAVVAIAKLAEHDLDIARQ-LLNGGIITITL 383
+ ++ + AGV L LL + A+ A+ + D DI Q +LN + L
Sbjct: 286 NDKIQAVIDAGVCRRLVELLMHNDYKVVSPALRAVGNIVTGD-DIQTQVILNCSALQSLL 344
Query: 384 ENLNKYNVYYKRSALYLLRAVAKHNEELASAIVRLGALEHIVSCLEDFDTQVKENAAWAV 563
L+ K+ A + + + N ++ ++S L+ + + ++ AAWA+
Sbjct: 345 HLLSSPKESIKKEACWTISNITAGNRAQIQTVIDANIFPALISILQTAEFRTRKEAAWAI 404
Query: 564 --GYIGKHSEQLAGLV 605
G +EQ+ LV
Sbjct: 405 TNATSGGSAEQIKYLV 420
>CR456743-1|CAG33024.1| 538|Homo sapiens KPNA1 protein.
Length = 538
Score = 35.1 bits (77), Expect = 0.22
Identities = 28/138 (20%), Positives = 57/138 (41%)
Frame = +3
Query: 243 LELLKPLLSDACSTIRQCAVVAIAKLAEHDLDIARQLLNGGIITITLENLNKYNVYYKRS 422
L +L LL + + + A A++ L++ D + +++ G+ +E L +
Sbjct: 256 LNVLSWLLFVSDTDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHNDYKVVSP 315
Query: 423 ALYLLRAVAKHNEELASAIVRLGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQLAGL 602
AL + + ++ I+ AL+ ++ L +K+ A W + I +
Sbjct: 316 ALRAVGNIVTGDDIQTQVILNCSALQSLLHLLSSPKESIKKEACWTISNITAGNRAQIQT 375
Query: 603 VVDAGTLPLLVLAFQEPE 656
V+DA P L+ Q E
Sbjct: 376 VIDANIFPALISILQTAE 393
Score = 33.9 bits (74), Expect = 0.51
Identities = 30/136 (22%), Positives = 57/136 (41%), Gaps = 3/136 (2%)
Frame = +3
Query: 207 SSNVKCLESAGVLELLKPLLSDACSTIRQCAVVAIAKLAEHDLDIARQ-LLNGGIITITL 383
+ ++ + AGV L LL + A+ A+ + D DI Q +LN + L
Sbjct: 286 NDKIQAVIDAGVCRRLVELLMHNDYKVVSPALRAVGNIVTGD-DIQTQVILNCSALQSLL 344
Query: 384 ENLNKYNVYYKRSALYLLRAVAKHNEELASAIVRLGALEHIVSCLEDFDTQVKENAAWAV 563
L+ K+ A + + + N ++ ++S L+ + + ++ AAWA+
Sbjct: 345 HLLSSPKESIKKEACWTISNITAGNRAQIQTVIDANIFPALISILQTAEFRTRKEAAWAI 404
Query: 564 --GYIGKHSEQLAGLV 605
G +EQ+ LV
Sbjct: 405 TNATSGGSAEQIKYLV 420
>BT006959-1|AAP35605.1| 538|Homo sapiens karyopherin alpha 1
(importin alpha 5) protein.
Length = 538
Score = 35.1 bits (77), Expect = 0.22
Identities = 28/138 (20%), Positives = 57/138 (41%)
Frame = +3
Query: 243 LELLKPLLSDACSTIRQCAVVAIAKLAEHDLDIARQLLNGGIITITLENLNKYNVYYKRS 422
L +L LL + + + A A++ L++ D + +++ G+ +E L +
Sbjct: 256 LNVLSWLLFVSDTDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHNDYKVVSP 315
Query: 423 ALYLLRAVAKHNEELASAIVRLGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQLAGL 602
AL + + ++ I+ AL+ ++ L +K+ A W + I +
Sbjct: 316 ALRAVGNIVTGDDIQTQVILNCSALQSLLHLLSSPKESIKKEACWTISNITAGNRAQIQT 375
Query: 603 VVDAGTLPLLVLAFQEPE 656
V+DA P L+ Q E
Sbjct: 376 VIDANIFPALISILQTAE 393
Score = 33.9 bits (74), Expect = 0.51
Identities = 30/136 (22%), Positives = 57/136 (41%), Gaps = 3/136 (2%)
Frame = +3
Query: 207 SSNVKCLESAGVLELLKPLLSDACSTIRQCAVVAIAKLAEHDLDIARQ-LLNGGIITITL 383
+ ++ + AGV L LL + A+ A+ + D DI Q +LN + L
Sbjct: 286 NDKIQAVIDAGVCRRLVELLMHNDYKVVSPALRAVGNIVTGD-DIQTQVILNCSALQSLL 344
Query: 384 ENLNKYNVYYKRSALYLLRAVAKHNEELASAIVRLGALEHIVSCLEDFDTQVKENAAWAV 563
L+ K+ A + + + N ++ ++S L+ + + ++ AAWA+
Sbjct: 345 HLLSSPKESIKKEACWTISNITAGNRAQIQTVIDANIFPALISILQTAEFRTRKEAAWAI 404
Query: 564 --GYIGKHSEQLAGLV 605
G +EQ+ LV
Sbjct: 405 TNATSGGSAEQIKYLV 420
>BC090864-1|AAH90864.1| 538|Homo sapiens karyopherin alpha 1
(importin alpha 5) protein.
Length = 538
Score = 35.1 bits (77), Expect = 0.22
Identities = 28/138 (20%), Positives = 57/138 (41%)
Frame = +3
Query: 243 LELLKPLLSDACSTIRQCAVVAIAKLAEHDLDIARQLLNGGIITITLENLNKYNVYYKRS 422
L +L LL + + + A A++ L++ D + +++ G+ +E L +
Sbjct: 256 LNVLSWLLFVSDTDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHNDYKVVSP 315
Query: 423 ALYLLRAVAKHNEELASAIVRLGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQLAGL 602
AL + + ++ I+ AL+ ++ L +K+ A W + I +
Sbjct: 316 ALRAVGNIVTGDDIQTQVILNCSALQSLLHLLSSPKESIKKEACWTISNITAGNRAQIQT 375
Query: 603 VVDAGTLPLLVLAFQEPE 656
V+DA P L+ Q E
Sbjct: 376 VIDANIFPALISILQTAE 393
Score = 33.9 bits (74), Expect = 0.51
Identities = 30/136 (22%), Positives = 57/136 (41%), Gaps = 3/136 (2%)
Frame = +3
Query: 207 SSNVKCLESAGVLELLKPLLSDACSTIRQCAVVAIAKLAEHDLDIARQ-LLNGGIITITL 383
+ ++ + AGV L LL + A+ A+ + D DI Q +LN + L
Sbjct: 286 NDKIQAVIDAGVCRRLVELLMHNDYKVVSPALRAVGNIVTGD-DIQTQVILNCSALQSLL 344
Query: 384 ENLNKYNVYYKRSALYLLRAVAKHNEELASAIVRLGALEHIVSCLEDFDTQVKENAAWAV 563
L+ K+ A + + + N ++ ++S L+ + + ++ AAWA+
Sbjct: 345 HLLSSPKESIKKEACWTISNITAGNRAQIQTVIDANIFPALISILQTAEFRTRKEAAWAI 404
Query: 564 --GYIGKHSEQLAGLV 605
G +EQ+ LV
Sbjct: 405 TNATSGGSAEQIKYLV 420
>BC003009-1|AAH03009.1| 538|Homo sapiens karyopherin alpha 1
(importin alpha 5) protein.
Length = 538
Score = 35.1 bits (77), Expect = 0.22
Identities = 28/138 (20%), Positives = 57/138 (41%)
Frame = +3
Query: 243 LELLKPLLSDACSTIRQCAVVAIAKLAEHDLDIARQLLNGGIITITLENLNKYNVYYKRS 422
L +L LL + + + A A++ L++ D + +++ G+ +E L +
Sbjct: 256 LNVLSWLLFVSDTDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHNDYKVVSP 315
Query: 423 ALYLLRAVAKHNEELASAIVRLGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQLAGL 602
AL + + ++ I+ AL+ ++ L +K+ A W + I +
Sbjct: 316 ALRAVGNIVTGDDIQTQVILNCSALQSLLHLLSSPKESIKKEACWTISNITAGNRAQIQT 375
Query: 603 VVDAGTLPLLVLAFQEPE 656
V+DA P L+ Q E
Sbjct: 376 VIDANIFPALISILQTAE 393
Score = 33.9 bits (74), Expect = 0.51
Identities = 30/136 (22%), Positives = 57/136 (41%), Gaps = 3/136 (2%)
Frame = +3
Query: 207 SSNVKCLESAGVLELLKPLLSDACSTIRQCAVVAIAKLAEHDLDIARQ-LLNGGIITITL 383
+ ++ + AGV L LL + A+ A+ + D DI Q +LN + L
Sbjct: 286 NDKIQAVIDAGVCRRLVELLMHNDYKVVSPALRAVGNIVTGD-DIQTQVILNCSALQSLL 344
Query: 384 ENLNKYNVYYKRSALYLLRAVAKHNEELASAIVRLGALEHIVSCLEDFDTQVKENAAWAV 563
L+ K+ A + + + N ++ ++S L+ + + ++ AAWA+
Sbjct: 345 HLLSSPKESIKKEACWTISNITAGNRAQIQTVIDANIFPALISILQTAEFRTRKEAAWAI 404
Query: 564 --GYIGKHSEQLAGLV 605
G +EQ+ LV
Sbjct: 405 TNATSGGSAEQIKYLV 420
>BC002374-1|AAH02374.1| 538|Homo sapiens karyopherin alpha 1
(importin alpha 5) protein.
Length = 538
Score = 35.1 bits (77), Expect = 0.22
Identities = 28/138 (20%), Positives = 57/138 (41%)
Frame = +3
Query: 243 LELLKPLLSDACSTIRQCAVVAIAKLAEHDLDIARQLLNGGIITITLENLNKYNVYYKRS 422
L +L LL + + + A A++ L++ D + +++ G+ +E L +
Sbjct: 256 LNVLSWLLFVSDTDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHNDYKVVSP 315
Query: 423 ALYLLRAVAKHNEELASAIVRLGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQLAGL 602
AL + + ++ I+ AL+ ++ L +K+ A W + I +
Sbjct: 316 ALRAVGNIVTGDDIQTQVILNCSALQSLLHLLSSPKESIKKEACWTISNITAGNRAQIQT 375
Query: 603 VVDAGTLPLLVLAFQEPE 656
V+DA P L+ Q E
Sbjct: 376 VIDANIFPALISILQTAE 393
Score = 33.9 bits (74), Expect = 0.51
Identities = 30/136 (22%), Positives = 57/136 (41%), Gaps = 3/136 (2%)
Frame = +3
Query: 207 SSNVKCLESAGVLELLKPLLSDACSTIRQCAVVAIAKLAEHDLDIARQ-LLNGGIITITL 383
+ ++ + AGV L LL + A+ A+ + D DI Q +LN + L
Sbjct: 286 NDKIQAVIDAGVCRRLVELLMHNDYKVVSPALRAVGNIVTGD-DIQTQVILNCSALQSLL 344
Query: 384 ENLNKYNVYYKRSALYLLRAVAKHNEELASAIVRLGALEHIVSCLEDFDTQVKENAAWAV 563
L+ K+ A + + + N ++ ++S L+ + + ++ AAWA+
Sbjct: 345 HLLSSPKESIKKEACWTISNITAGNRAQIQTVIDANIFPALISILQTAEFRTRKEAAWAI 404
Query: 564 --GYIGKHSEQLAGLV 605
G +EQ+ LV
Sbjct: 405 TNATSGGSAEQIKYLV 420
>BT009843-1|AAP88845.1| 536|Homo sapiens karyopherin alpha 6
(importin alpha 7) protein.
Length = 536
Score = 34.3 bits (75), Expect = 0.39
Identities = 27/138 (19%), Positives = 58/138 (42%)
Frame = +3
Query: 243 LELLKPLLSDACSTIRQCAVVAIAKLAEHDLDIARQLLNGGIITITLENLNKYNVYYKRS 422
L +L LL + S + A A++ L++ + + +++ G+ +E L +
Sbjct: 254 LPVLSRLLFSSDSDLLADACWALSYLSDGPNEKIQAVIDSGVCRRLVELLMHNDYKVASP 313
Query: 423 ALYLLRAVAKHNEELASAIVRLGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQLAGL 602
AL + + ++ I+ AL ++ L +++ A W + I +
Sbjct: 314 ALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTISNITAGNRAQIQA 373
Query: 603 VVDAGTLPLLVLAFQEPE 656
V+DA P+L+ Q+ E
Sbjct: 374 VIDANIFPVLIEILQKAE 391
>BC067848-1|AAH67848.1| 529|Homo sapiens karyopherin alpha 2 (RAG
cohort 1, importin alpha 1) protein.
Length = 529
Score = 34.3 bits (75), Expect = 0.39
Identities = 21/71 (29%), Positives = 30/71 (42%), Gaps = 1/71 (1%)
Frame = +3
Query: 429 YLLRAVAKHNEELASAIVRLGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQLAGLVV 608
+ L +A E A+V GA+ +S L + E WA+G I LV+
Sbjct: 142 WALTNIASGTSEQTKAVVDGGAIRAFISLLASPHAHISEQDVWALGNIAGDGSVFRDLVI 201
Query: 609 DAGTL-PLLVL 638
G + PLL L
Sbjct: 202 KYGAVDPLLAL 212
Score = 33.9 bits (74), Expect = 0.51
Identities = 30/148 (20%), Positives = 58/148 (39%), Gaps = 5/148 (3%)
Frame = +3
Query: 207 SSNVKCLESAGVLELLKPLLSDACSTIRQCAVVAIAKLAE-----HDLDIARQLLNGGII 371
S K + G + LL+ + I + V A+ +A DL I ++ +
Sbjct: 152 SEQTKAVVDGGAIRAFISLLASPHAHISEQDVWALGNIAGDGSVFRDLVIKYGAVDPLLA 211
Query: 372 TITLENLNKYNVYYKRSALYLLRAVAKHNEELASAIVRLGALEHIVSCLEDFDTQVKENA 551
+ + +++ Y R+ + L + ++ L +V L D +V +
Sbjct: 212 LLAVPDMSSLACGYLRNLTWTLSNLCRNKNPAPPIDAVEQILPTLVRLLHHDDPEVLADT 271
Query: 552 AWAVGYIGKHSEQLAGLVVDAGTLPLLV 635
WA+ Y+ + G+VV G +P LV
Sbjct: 272 CWAISYLTDGPNERIGMVVKTGVVPQLV 299
Score = 31.9 bits (69), Expect = 2.1
Identities = 23/110 (20%), Positives = 46/110 (41%)
Frame = +3
Query: 306 AIAKLAEHDLDIARQLLNGGIITITLENLNKYNVYYKRSALYLLRAVAKHNEELASAIVR 485
AI+ L + + ++ G++ ++ L + AL + + +E ++
Sbjct: 274 AISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVTPALRAIGNIVTGTDEQTQVVID 333
Query: 486 LGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQLAGLVVDAGTLPLLV 635
GAL S L + T +++ A W + I + VV+ G +P LV
Sbjct: 334 AGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLV 383
>BC020520-1|AAH20520.1| 536|Homo sapiens karyopherin alpha 6
(importin alpha 7) protein.
Length = 536
Score = 34.3 bits (75), Expect = 0.39
Identities = 27/138 (19%), Positives = 58/138 (42%)
Frame = +3
Query: 243 LELLKPLLSDACSTIRQCAVVAIAKLAEHDLDIARQLLNGGIITITLENLNKYNVYYKRS 422
L +L LL + S + A A++ L++ + + +++ G+ +E L +
Sbjct: 254 LPVLSRLLFSSDSDLLADACWALSYLSDGPNEKIQAVIDSGVCRRLVELLMHNDYKVASP 313
Query: 423 ALYLLRAVAKHNEELASAIVRLGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQLAGL 602
AL + + ++ I+ AL ++ L +++ A W + I +
Sbjct: 314 ALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTISNITAGNRAQIQA 373
Query: 603 VVDAGTLPLLVLAFQEPE 656
V+DA P+L+ Q+ E
Sbjct: 374 VIDANIFPVLIEILQKAE 391
>AL445248-5|CAH71948.1| 536|Homo sapiens karyopherin alpha 6
(importin alpha 7) protein.
Length = 536
Score = 34.3 bits (75), Expect = 0.39
Identities = 27/138 (19%), Positives = 58/138 (42%)
Frame = +3
Query: 243 LELLKPLLSDACSTIRQCAVVAIAKLAEHDLDIARQLLNGGIITITLENLNKYNVYYKRS 422
L +L LL + S + A A++ L++ + + +++ G+ +E L +
Sbjct: 254 LPVLSRLLFSSDSDLLADACWALSYLSDGPNEKIQAVIDSGVCRRLVELLMHNDYKVASP 313
Query: 423 ALYLLRAVAKHNEELASAIVRLGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQLAGL 602
AL + + ++ I+ AL ++ L +++ A W + I +
Sbjct: 314 ALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTISNITAGNRAQIQA 373
Query: 603 VVDAGTLPLLVLAFQEPE 656
V+DA P+L+ Q+ E
Sbjct: 374 VIDANIFPVLIEILQKAE 391
>AL049795-3|CAI22056.1| 536|Homo sapiens karyopherin alpha 6
(importin alpha 7) protein.
Length = 536
Score = 34.3 bits (75), Expect = 0.39
Identities = 27/138 (19%), Positives = 58/138 (42%)
Frame = +3
Query: 243 LELLKPLLSDACSTIRQCAVVAIAKLAEHDLDIARQLLNGGIITITLENLNKYNVYYKRS 422
L +L LL + S + A A++ L++ + + +++ G+ +E L +
Sbjct: 254 LPVLSRLLFSSDSDLLADACWALSYLSDGPNEKIQAVIDSGVCRRLVELLMHNDYKVASP 313
Query: 423 ALYLLRAVAKHNEELASAIVRLGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQLAGL 602
AL + + ++ I+ AL ++ L +++ A W + I +
Sbjct: 314 ALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTISNITAGNRAQIQA 373
Query: 603 VVDAGTLPLLVLAFQEPE 656
V+DA P+L+ Q+ E
Sbjct: 374 VIDANIFPVLIEILQKAE 391
>AL049795-1|CAI22054.1| 321|Homo sapiens karyopherin alpha 6
(importin alpha 7) protein.
Length = 321
Score = 34.3 bits (75), Expect = 0.39
Identities = 27/138 (19%), Positives = 58/138 (42%)
Frame = +3
Query: 243 LELLKPLLSDACSTIRQCAVVAIAKLAEHDLDIARQLLNGGIITITLENLNKYNVYYKRS 422
L +L LL + S + A A++ L++ + + +++ G+ +E L +
Sbjct: 161 LPVLSRLLFSSDSDLLADACWALSYLSDGPNEKIQAVIDSGVCRRLVELLMHNDYKVASP 220
Query: 423 ALYLLRAVAKHNEELASAIVRLGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQLAGL 602
AL + + ++ I+ AL ++ L +++ A W + I +
Sbjct: 221 ALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTISNITAGNRAQIQA 280
Query: 603 VVDAGTLPLLVLAFQEPE 656
V+DA P+L+ Q+ E
Sbjct: 281 VIDANIFPVLIEILQKAE 298
>AF060543-1|AAC15233.1| 536|Homo sapiens importin alpha 7 subunit
protein.
Length = 536
Score = 34.3 bits (75), Expect = 0.39
Identities = 27/138 (19%), Positives = 58/138 (42%)
Frame = +3
Query: 243 LELLKPLLSDACSTIRQCAVVAIAKLAEHDLDIARQLLNGGIITITLENLNKYNVYYKRS 422
L +L LL + S + A A++ L++ + + +++ G+ +E L +
Sbjct: 254 LPVLSRLLFSSDSDLLADACWALSYLSDGPNEKIQAVIDSGVCRRLVELLMHNDYKVASP 313
Query: 423 ALYLLRAVAKHNEELASAIVRLGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQLAGL 602
AL + + ++ I+ AL ++ L +++ A W + I +
Sbjct: 314 ALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTISNITAGNRAQIQA 373
Query: 603 VVDAGTLPLLVLAFQEPE 656
V+DA P+L+ Q+ E
Sbjct: 374 VIDANIFPVLIEILQKAE 391
>BC047409-1|AAH47409.1| 539|Homo sapiens karyopherin alpha 5
(importin alpha 6) protein.
Length = 539
Score = 33.1 bits (72), Expect = 0.90
Identities = 27/138 (19%), Positives = 56/138 (40%)
Frame = +3
Query: 243 LELLKPLLSDACSTIRQCAVVAIAKLAEHDLDIARQLLNGGIITITLENLNKYNVYYKRS 422
L +L LL + + A++ L++ D + +++ G+ +E L +
Sbjct: 257 LNVLSRLLFSSDPDVLADVCWALSYLSDGPNDKIQAVIDSGVCRRLVELLMHNDYKVVSP 316
Query: 423 ALYLLRAVAKHNEELASAIVRLGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQLAGL 602
AL + + ++ I+ AL ++ L +++ A W V I +
Sbjct: 317 ALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTVSNITAGNRAQIQA 376
Query: 603 VVDAGTLPLLVLAFQEPE 656
V+DA P+L+ Q+ E
Sbjct: 377 VIDANIFPVLIEILQKAE 394
>AL132795-5|CAI20500.1| 539|Homo sapiens karyopherin alpha 5
(importin alpha 6) protein.
Length = 539
Score = 33.1 bits (72), Expect = 0.90
Identities = 27/138 (19%), Positives = 56/138 (40%)
Frame = +3
Query: 243 LELLKPLLSDACSTIRQCAVVAIAKLAEHDLDIARQLLNGGIITITLENLNKYNVYYKRS 422
L +L LL + + A++ L++ D + +++ G+ +E L +
Sbjct: 257 LNVLSRLLFSSDPDVLADVCWALSYLSDGPNDKIQAVIDSGVCRRLVELLMHNDYKVVSP 316
Query: 423 ALYLLRAVAKHNEELASAIVRLGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQLAGL 602
AL + + ++ I+ AL ++ L +++ A W V I +
Sbjct: 317 ALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTVSNITAGNRAQIQA 376
Query: 603 VVDAGTLPLLVLAFQEPE 656
V+DA P+L+ Q+ E
Sbjct: 377 VIDANIFPVLIEILQKAE 394
>AF005361-1|AAC51868.1| 536|Homo sapiens importin alpha 6 protein.
Length = 536
Score = 33.1 bits (72), Expect = 0.90
Identities = 27/138 (19%), Positives = 56/138 (40%)
Frame = +3
Query: 243 LELLKPLLSDACSTIRQCAVVAIAKLAEHDLDIARQLLNGGIITITLENLNKYNVYYKRS 422
L +L LL + + A++ L++ D + +++ G+ +E L +
Sbjct: 254 LNVLSRLLFSSDPDVLADVCWALSYLSDGPNDKIQAVIDSGVCRRLVELLMHNDYKVVSP 313
Query: 423 ALYLLRAVAKHNEELASAIVRLGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQLAGL 602
AL + + ++ I+ AL ++ L +++ A W V I +
Sbjct: 314 ALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTVSNITAGNRAQIQA 373
Query: 603 VVDAGTLPLLVLAFQEPE 656
V+DA P+L+ Q+ E
Sbjct: 374 VIDANIFPVLIEILQKAE 391
>AK126073-1|BAC86425.1| 1080|Homo sapiens protein ( Homo sapiens cDNA
FLJ44085 fis, clone TESTI4041053. ).
Length = 1080
Score = 31.9 bits (69), Expect = 2.1
Identities = 23/112 (20%), Positives = 49/112 (43%)
Frame = +3
Query: 228 ESAGVLELLKPLLSDACSTIRQCAVVAIAKLAEHDLDIARQLLNGGIITITLENLNKYNV 407
E G+ L++ L SD+ ++ + AIA++ + +I + G I + +
Sbjct: 863 EHKGLPYLIRFLSSDS-DVLKAVSSAAIAEVGRDNKEIQDAIAMEGAIPPLVALFKGKQI 921
Query: 408 YYKRSALYLLRAVAKHNEELASAIVRLGALEHIVSCLEDFDTQVKENAAWAV 563
+ + ++A HN + A + ++++ L+ F VKE A A+
Sbjct: 922 SVQMKGAMAVESLASHNALIQKAFLEKSLTKYLLKLLKAFQIDVKEQGAVAL 973
>AK058144-1|BAB71684.1| 237|Homo sapiens protein ( Homo sapiens
cDNA FLJ25415 fis, clone TST03443. ).
Length = 237
Score = 31.9 bits (69), Expect = 2.1
Identities = 23/112 (20%), Positives = 49/112 (43%)
Frame = +3
Query: 228 ESAGVLELLKPLLSDACSTIRQCAVVAIAKLAEHDLDIARQLLNGGIITITLENLNKYNV 407
E G+ L++ L SD+ ++ + AIA++ + +I + G I + +
Sbjct: 20 EHKGLPYLIRFLSSDS-DVLKAVSSAAIAEVGRDNKEIQDAIAMEGAIPPLVALFKGKQI 78
Query: 408 YYKRSALYLLRAVAKHNEELASAIVRLGALEHIVSCLEDFDTQVKENAAWAV 563
+ + ++A HN + A + ++++ L+ F VKE A A+
Sbjct: 79 SVQMKGAMAVESLASHNALIQKAFLEKSLTKYLLKLLKAFQIDVKEQGAVAL 130
>AJ549812-1|CAD71147.1| 1363|Homo sapiens hypothetical protein
protein.
Length = 1363
Score = 31.9 bits (69), Expect = 2.1
Identities = 23/112 (20%), Positives = 49/112 (43%)
Frame = +3
Query: 228 ESAGVLELLKPLLSDACSTIRQCAVVAIAKLAEHDLDIARQLLNGGIITITLENLNKYNV 407
E G+ L++ L SD+ ++ + AIA++ + +I + G I + +
Sbjct: 792 EHKGLPYLIRFLSSDS-DVLKAVSSAAIAEVGRDNKEIQDAIAMEGAIPPLVALFKGKQI 850
Query: 408 YYKRSALYLLRAVAKHNEELASAIVRLGALEHIVSCLEDFDTQVKENAAWAV 563
+ + ++A HN + A + ++++ L+ F VKE A A+
Sbjct: 851 SVQMKGAMAVESLASHNALIQKAFLEKSLTKYLLKLLKAFQIDVKEQGAVAL 902
>AL390866-5|CAI12711.1| 1044|Homo sapiens novel protein protein.
Length = 1044
Score = 31.5 bits (68), Expect = 2.7
Identities = 22/77 (28%), Positives = 37/77 (48%)
Frame = +3
Query: 423 ALYLLRAVAKHNEELASAIVRLGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQLAGL 602
AL +R + E AI +G LE +++ LE + + K + + I H+ Q+
Sbjct: 472 ALCSMRDFSLAQETCQLAIRDVGGLEVLINLLETDEVKCKIGSLKILKEIS-HNPQIRQN 530
Query: 603 VVDAGTLPLLVLAFQEP 653
+VD G LP++V P
Sbjct: 531 IVDLGGLPIMVNILDSP 547
>AL355372-1|CAI16402.1| 1044|Homo sapiens novel protein protein.
Length = 1044
Score = 31.5 bits (68), Expect = 2.7
Identities = 22/77 (28%), Positives = 37/77 (48%)
Frame = +3
Query: 423 ALYLLRAVAKHNEELASAIVRLGALEHIVSCLEDFDTQVKENAAWAVGYIGKHSEQLAGL 602
AL +R + E AI +G LE +++ LE + + K + + I H+ Q+
Sbjct: 472 ALCSMRDFSLAQETCQLAIRDVGGLEVLINLLETDEVKCKIGSLKILKEIS-HNPQIRQN 530
Query: 603 VVDAGTLPLLVLAFQEP 653
+VD G LP++V P
Sbjct: 531 IVDLGGLPIMVNILDSP 547
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 91,701,772
Number of Sequences: 237096
Number of extensions: 1831495
Number of successful extensions: 3781
Number of sequences better than 10.0: 53
Number of HSP's better than 10.0 without gapping: 3552
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3741
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7366354010
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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