Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmte1c04
(727 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
L19559-1|AAA36659.1| 603|Homo sapiens protein kinase protein. 264 2e-70
X73458-1|CAA51837.1| 603|Homo sapiens protein kinase protein. 262 7e-70
BC014846-1|AAH14846.1| 603|Homo sapiens polo-like kinase 1 (Dro... 262 7e-70
BC003002-1|AAH03002.1| 603|Homo sapiens polo-like kinase 1 (Dro... 262 7e-70
BC002369-1|AAH02369.1| 603|Homo sapiens polo-like kinase 1 (Dro... 262 7e-70
X75932-1|CAA53536.1| 603|Homo sapiens Serine/Threonine protein ... 260 5e-69
U01038-1|AAA56634.1| 603|Homo sapiens pLK protein. 258 2e-68
AB084459-1|BAD93352.1| 247|Homo sapiens polo-like kinase 1 delt... 254 2e-67
BC013879-1|AAH13879.1| 685|Homo sapiens polo-like kinase 2 (Dro... 214 3e-55
AK098163-1|BAC05247.1| 372|Homo sapiens protein ( Homo sapiens ... 214 3e-55
AF223574-1|AAF62897.1| 685|Homo sapiens serum-inducible kinase ... 214 3e-55
AF059617-1|AAC14573.1| 685|Homo sapiens serum-inducible kinase ... 214 3e-55
U56998-1|AAC50637.1| 607|Homo sapiens putative serine/threonine... 203 4e-52
BC013899-1|AAH13899.1| 646|Homo sapiens polo-like kinase 3 (Dro... 203 4e-52
AY764184-1|AAU88146.1| 646|Homo sapiens polo-like kinase 3 (Dro... 203 4e-52
AL592166-11|CAI13006.1| 646|Homo sapiens polo-like kinase 3 (Dr... 203 4e-52
AJ293866-1|CAC10659.1| 646|Homo sapiens FNK serine/threonine pr... 203 4e-52
AB209875-1|BAD93112.1| 621|Homo sapiens polo-like kinase 3 vari... 198 2e-50
U85755-1|AAD00575.1| 299|Homo sapiens serum-inducible kinase pr... 175 2e-43
AK131198-1|BAD18393.1| 706|Homo sapiens protein ( Homo sapiens ... 174 2e-43
AB209179-1|BAD92416.1| 546|Homo sapiens polo-like kinase varian... 160 4e-39
AB006972-1|BAB69958.1| 970|Homo sapiens Sak protein. 140 6e-33
Y13115-1|CAA73575.1| 970|Homo sapiens serine/threonine protein ... 138 1e-32
BC036023-1|AAH36023.1| 970|Homo sapiens polo-like kinase 4 (Dro... 138 1e-32
BC017306-1|AAH17306.1| 628|Homo sapiens NUAK family, SNF1-like ... 116 9e-26
AK074830-1|BAC11234.1| 628|Homo sapiens protein ( Homo sapiens ... 116 9e-26
AB011109-1|BAA25463.2| 698|Homo sapiens KIAA0537 protein protein. 110 4e-24
L33881-1|AAB17011.1| 587|Homo sapiens protein kinase C iota pro... 109 7e-24
L18964-1|AAA60171.1| 587|Homo sapiens protein kinase C iota pro... 109 7e-24
BC022016-1|AAH22016.3| 587|Homo sapiens protein kinase C, iota ... 109 7e-24
U78073-1|AAB36946.1| 136|Homo sapiens polo like kinase protein. 108 2e-23
Z15108-1|CAA78813.1| 584|Homo sapiens protein kinase C zeta pro... 107 4e-23
BT007082-1|AAP35745.1| 592|Homo sapiens protein kinase C, zeta ... 107 4e-23
BC014270-1|AAH14270.1| 592|Homo sapiens protein kinase C, zeta ... 107 4e-23
BC008058-1|AAH08058.1| 592|Homo sapiens protein kinase C, zeta ... 107 4e-23
AL645703-1|CAI21535.1| 592|Homo sapiens protein kinase C, zeta ... 107 4e-23
AL590822-9|CAI12484.1| 592|Homo sapiens protein kinase C, zeta ... 107 4e-23
AL391845-5|CAI15438.1| 592|Homo sapiens protein kinase C, zeta ... 107 4e-23
X90725-1|CAA62260.1| 136|Homo sapiens polo-like kinase protein. 106 7e-23
L14283-1|AAA36488.1| 592|Homo sapiens protein kinase C zeta pro... 106 7e-23
BC020479-1|AAH20479.1| 466|Homo sapiens AKT3 protein protein. 104 4e-22
AY005799-1|AAF91073.1| 465|Homo sapiens protein kinase B gamma ... 104 4e-22
AL662889-3|CAH73073.1| 479|Homo sapiens v-akt murine thymoma vi... 104 4e-22
AL662889-2|CAH73072.1| 465|Homo sapiens v-akt murine thymoma vi... 104 4e-22
AL592151-2|CAH72892.1| 479|Homo sapiens v-akt murine thymoma vi... 104 4e-22
AL592151-1|CAH72891.1| 465|Homo sapiens v-akt murine thymoma vi... 104 4e-22
AL591721-2|CAH71867.1| 479|Homo sapiens v-akt murine thymoma vi... 104 4e-22
AL591721-1|CAH71866.1| 465|Homo sapiens v-akt murine thymoma vi... 104 4e-22
AJ245709-1|CAB53537.1| 479|Homo sapiens Akt-3 protein protein. 104 4e-22
AF135794-1|AAD24196.1| 479|Homo sapiens AKT3 protein kinase pro... 104 4e-22
AF124141-1|AAD29089.1| 479|Homo sapiens protein kinase B gamma ... 104 4e-22
AF085234-1|AAL40392.1| 479|Homo sapiens STK-2 protein. 104 4e-22
M34181-1|AAA60170.1| 351|Homo sapiens cAMP-dependent protein ki... 103 5e-22
DQ667174-1|ABG25919.1| 398|Homo sapiens protein kinase, cAMP-de... 103 5e-22
BC016285-1|AAH16285.1| 257|Homo sapiens protein kinase, cAMP-de... 103 5e-22
AL450063-11|CAI16854.1| 264|Homo sapiens protein kinase, cAMP-d... 103 5e-22
AL450063-10|CAI16853.1| 209|Homo sapiens protein kinase, cAMP-d... 103 5e-22
AL450063-7|CAI16850.1| 245|Homo sapiens protein kinase, cAMP-de... 103 5e-22
AL450063-6|CAI16849.1| 214|Homo sapiens protein kinase, cAMP-de... 103 5e-22
AL450063-3|CAI16846.1| 398|Homo sapiens protein kinase, cAMP-de... 103 5e-22
AL450063-2|CAI16845.1| 351|Homo sapiens protein kinase, cAMP-de... 103 5e-22
AL450063-1|CAI16844.1| 257|Homo sapiens protein kinase, cAMP-de... 103 5e-22
AL359504-2|CAI14541.1| 351|Homo sapiens protein kinase, cAMP-de... 103 5e-22
AL359504-1|CAI14540.1| 257|Homo sapiens protein kinase, cAMP-de... 103 5e-22
AB209189-1|BAD92426.1| 365|Homo sapiens cAMP-dependent protein ... 103 5e-22
M34182-1|AAC41690.1| 360|Homo sapiens protein kinase A gamma-su... 103 9e-22
DQ667175-1|ABG25920.1| 351|Homo sapiens protein kinase, cAMP-de... 103 9e-22
BC043487-1|AAH43487.1| 505|Homo sapiens calcium/calmodulin-depe... 103 9e-22
BC039888-1|AAH39888.1| 351|Homo sapiens protein kinase, cAMP-de... 103 9e-22
AL162730-1|CAH71828.1| 351|Homo sapiens protein kinase, cAMP-de... 103 9e-22
AJ001597-1|CAA04863.1| 351|Homo sapiens cAMP-dependent protein ... 103 9e-22
AF425301-1|AAN37387.1| 505|Homo sapiens CAMKK alpha protein pro... 103 9e-22
AF425232-1|AAN37386.1| 505|Homo sapiens CaMKK alpha protein pro... 103 9e-22
Y11950-1|CAA72694.1| 406|Homo sapiens phosphorylase kinase gamm... 102 2e-21
M95936-1|AAA58364.1| 481|Homo sapiens protein serine/threonine ... 102 2e-21
M77198-1|AAA36585.1| 520|Homo sapiens rac protein kinase-beta p... 102 2e-21
M31606-1|AAA36442.1| 406|Homo sapiens phosphorylase kinase prot... 102 2e-21
BC120994-1|AAI20995.1| 481|Homo sapiens v-akt murine thymoma vi... 102 2e-21
BC032709-1|AAH32709.1| 344|Homo sapiens AKT2 protein protein. 102 2e-21
BC002541-1|AAH02541.1| 406|Homo sapiens phosphorylase kinase, g... 102 2e-21
BC121154-1|AAI21155.1| 465|Homo sapiens v-akt murine thymoma vi... 101 2e-21
BC035058-1|AAH35058.1| 351|Homo sapiens protein kinase, cAMP-de... 101 2e-21
BC031231-1|AAH31231.1| 514|Homo sapiens serine/threonine kinase... 101 3e-21
AL450063-9|CAI16852.1| 197|Homo sapiens protein kinase, cAMP-de... 101 3e-21
AK093251-1|BAC04109.1| 514|Homo sapiens protein ( Homo sapiens ... 101 3e-21
AJ303380-1|CAC29064.1| 514|Homo sapiens serine/threonine kinase... 101 3e-21
X07767-1|CAA30597.1| 351|Homo sapiens protein ( Human mRNA for ... 101 3e-21
U64205-1|AAC15093.1| 729|Homo sapiens Cdc25C associated protein... 101 3e-21
M80359-1|AAA59991.1| 713|Homo sapiens protein p78 protein. 101 3e-21
M80335-1|AAA60094.1| 207|Homo sapiens protein kinase A-alpha pr... 101 3e-21
DQ667173-1|ABG25918.1| 351|Homo sapiens protein kinase, cAMP-de... 101 3e-21
BC108259-1|AAI08260.1| 351|Homo sapiens protein kinase, cAMP-de... 101 3e-21
BC039846-1|AAH39846.1| 351|Homo sapiens protein kinase, cAMP-de... 101 3e-21
BC024773-1|AAH24773.1| 729|Homo sapiens MAP/microtubule affinit... 101 3e-21
AF465413-1|AAL69982.1| 753|Homo sapiens MAP/microtubule affinit... 101 3e-21
AF387637-1|AAK82367.1| 744|Homo sapiens Ser/Thr protein kinase ... 101 3e-21
BC019916-1|AAH19916.2| 506|Homo sapiens NIMA (never in mitosis ... 100 6e-21
AL139082-7|CAI12895.1| 507|Homo sapiens NIMA (never in mitosis ... 100 6e-21
AK131359-1|BAD18511.1| 510|Homo sapiens protein ( Homo sapiens ... 100 6e-21
X97630-1|CAA66229.1| 745|Homo sapiens serine/threonine protein ... 99 8e-21
BT007342-1|AAP36006.1| 755|Homo sapiens MAP/microtubule affinit... 99 8e-21
BC084540-1|AAH84540.1| 724|Homo sapiens MAP/microtubule affinit... 99 8e-21
BC008771-1|AAH08771.2| 778|Homo sapiens MARK2 protein protein. 99 8e-21
AF387638-1|AAK82368.1| 691|Homo sapiens Ser/Thr protein kinase ... 99 8e-21
AB188493-1|BAD37141.1| 719|Homo sapiens serine/threonine kinase... 99 8e-21
AB072828-1|BAC15599.1| 489|Homo sapiens NIMA-related protein ki... 99 1e-20
Z84486-1|CAI21678.1| 526|Homo sapiens serum/glucocorticoid regu... 98 2e-20
Y10032-1|CAA71138.1| 431|Homo sapiens serine/threonine protein ... 98 2e-20
BC126432-1|AAI26433.1| 454|Homo sapiens death-associated protei... 98 2e-20
BC126430-1|AAI26431.1| 454|Homo sapiens death-associated protei... 98 2e-20
BC001263-1|AAH01263.1| 431|Homo sapiens serum/glucocorticoid re... 98 2e-20
AL355881-2|CAH72579.1| 526|Homo sapiens serum/glucocorticoid re... 98 2e-20
AL135839-4|CAI19721.1| 526|Homo sapiens serum/glucocorticoid re... 98 2e-20
AL135839-3|CAI19720.1| 445|Homo sapiens serum/glucocorticoid re... 98 2e-20
AL135839-2|CAI19719.1| 431|Homo sapiens serum/glucocorticoid re... 98 2e-20
AL135839-1|CAI19718.1| 421|Homo sapiens serum/glucocorticoid re... 98 2e-20
AJ000512-1|CAA04146.1| 431|Homo sapiens serine/threonine protei... 98 2e-20
AF153609-1|AAD41091.1| 431|Homo sapiens serine/threonine protei... 98 2e-20
AB022341-1|BAA81746.1| 454|Homo sapiens ZIP kinase protein. 98 2e-20
AB007144-1|BAA24955.1| 454|Homo sapiens ZIP-kinase protein. 98 2e-20
M63167-1|AAA36539.1| 480|Homo sapiens rac protein kinase-alpha ... 98 3e-20
L07032-1|AAA60101.1| 706|Homo sapiens protein kinase C-theta pr... 98 3e-20
L01087-1|AAA75571.1| 706|Homo sapiens protein kinase C-theta pr... 98 3e-20
BC113359-1|AAI13360.1| 706|Homo sapiens protein kinase C, theta... 98 3e-20
BC101465-1|AAI01466.1| 706|Homo sapiens protein kinase C, theta... 98 3e-20
BC084538-1|AAH84538.1| 480|Homo sapiens v-akt murine thymoma vi... 98 3e-20
BC000479-1|AAH00479.1| 480|Homo sapiens v-akt murine thymoma vi... 98 3e-20
AL158043-2|CAC12904.2| 706|Homo sapiens protein kinase C, theta... 98 3e-20
AL158043-1|CAI16127.1| 478|Homo sapiens protein kinase C, theta... 98 3e-20
AL137145-2|CAC10200.2| 706|Homo sapiens protein kinase C, theta... 98 3e-20
AL137145-1|CAI15756.1| 478|Homo sapiens protein kinase C, theta... 98 3e-20
AF283830-1|AAL55732.1| 480|Homo sapiens AKT1 protein. 98 3e-20
AB019245-1|BAA37145.1| 481|Homo sapiens S6 kinase b protein. 98 3e-20
U33053-1|AAC50209.1| 942|Homo sapiens PRK1 protein. 97 4e-20
U33052-1|AAC50208.1| 984|Homo sapiens PRK2 protein. 97 4e-20
S75548-1|AAB33346.1| 984|Homo sapiens protein kinase PRK2 protein. 97 4e-20
S75546-1|AAB33345.1| 942|Homo sapiens protein kinase PRK1 protein. 97 4e-20
D26181-1|BAA05169.1| 942|Homo sapiens PKN protein. 97 4e-20
BC040061-1|AAH40061.1| 942|Homo sapiens protein kinase N1 protein. 97 4e-20
AL136381-3|CAI23271.1| 984|Homo sapiens protein kinase N2 protein. 97 4e-20
AJ271722-1|CAB71146.1| 714|Homo sapiens putative serine/threoni... 97 4e-20
U08316-1|AAA81952.1| 740|Homo sapiens insulin-stimulated protei... 97 6e-20
L07599-1|AAC82495.1| 580|Homo sapiens ribosomal protein S6 kina... 97 6e-20
BC096302-1|AAH96302.1| 740|Homo sapiens ribosomal protein S6 ki... 97 6e-20
BC096301-1|AAH96301.1| 740|Homo sapiens ribosomal protein S6 ki... 97 6e-20
AY120867-1|AAM55491.1| 752|Homo sapiens MAP/microtubule affinit... 97 6e-20
AY057448-1|AAL23683.1| 752|Homo sapiens MARK4 serine/threonine ... 97 6e-20
AL807772-3|CAI39687.1| 740|Homo sapiens ribosomal protein S6 ki... 97 6e-20
AL807772-1|CAI39684.1| 227|Homo sapiens ribosomal protein S6 ki... 97 6e-20
AL732366-2|CAI40548.1| 740|Homo sapiens ribosomal protein S6 ki... 97 6e-20
AK075272-1|BAC11510.1| 752|Homo sapiens protein ( Homo sapiens ... 97 6e-20
AB208933-1|BAD92170.1| 806|Homo sapiens ribosomal protein S6 ki... 97 6e-20
AB102662-1|BAC81131.1| 726|Homo sapiens RPS6KA3 protein. 97 6e-20
AB058763-1|BAB47489.1| 689|Homo sapiens KIAA1860 protein protein. 97 6e-20
Z93016-2|CAI19815.1| 487|Homo sapiens serine/threonine kinase 4... 97 7e-20
Z93016-1|CAB07508.2| 462|Homo sapiens serine/threonine kinase 4... 97 7e-20
U60207-1|AAB17262.1| 487|Homo sapiens serine/threonine protein ... 97 7e-20
U18297-1|AAA83254.1| 487|Homo sapiens MST1 protein. 97 7e-20
BC125199-1|AAI25200.1| 936|Homo sapiens PKN2 protein protein. 97 7e-20
BC093768-1|AAH93768.1| 487|Homo sapiens serine/threonine kinase... 97 7e-20
BC058916-1|AAH58916.1| 405|Homo sapiens STK4 protein protein. 97 7e-20
BC015332-1|AAH15332.1| 405|Homo sapiens Unknown (protein for IM... 97 7e-20
AY702977-1|AAU29340.1| 643|Homo sapiens protein kinase C theta ... 97 7e-20
AL109839-4|CAI95634.1| 487|Homo sapiens serine/threonine kinase... 97 7e-20
AL109839-3|CAI95633.1| 462|Homo sapiens serine/threonine kinase... 97 7e-20
AB209315-1|BAD92552.1| 511|Homo sapiens serine/threonine kinase... 97 7e-20
Y15056-1|CAA75341.1| 556|Homo sapiens PkB kinase protein. 96 1e-19
CR536517-1|CAG38755.1| 556|Homo sapiens PDPK1 protein. 96 1e-19
BC117183-1|AAI17184.1| 926|Homo sapiens SNF1-like kinase 2 prot... 96 1e-19
BC114478-1|AAI14479.1| 795|Homo sapiens MARK1 protein protein. 96 1e-19
BC113869-1|AAI13870.1| 795|Homo sapiens MARK1 protein protein. 96 1e-19
BC113459-1|AAI13460.1| 926|Homo sapiens SNF1-like kinase 2 prot... 96 1e-19
BC096303-1|AAH96303.1| 740|Homo sapiens ribosomal protein S6 ki... 96 1e-19
BC062558-1|AAH62558.1| 889|Homo sapiens protein kinase N3 protein. 96 1e-19
BC012103-1|AAH12103.1| 556|Homo sapiens 3-phosphoinositide depe... 96 1e-19
AL592406-3|CAH72463.1| 795|Homo sapiens MAP/microtubule affinit... 96 1e-19
AL441992-1|CAI15401.1| 889|Homo sapiens protein kinase N3 protein. 96 1e-19
AF154845-1|AAF72103.1| 795|Homo sapiens MARK protein. 96 1e-19
AF017995-1|AAC51825.1| 556|Homo sapiens 3-phosphoinositide depe... 96 1e-19
AC005591-1|AAC33797.1| 367|Homo sapiens PkB-like protein. 96 1e-19
AB209835-1|BAD93072.1| 492|Homo sapiens 3-phosphoinositide depe... 96 1e-19
AB084424-1|BAB91442.1| 346|Homo sapiens KIAA0781 protein protein. 96 1e-19
AB018324-1|BAA34501.3| 950|Homo sapiens KIAA0781 protein protein. 96 1e-19
X80229-1|CAA56515.1| 479|Homo sapiens serine/threonine protein ... 96 1e-19
BC114506-1|AAI14507.1| 370|Homo sapiens death-associated protei... 96 1e-19
AF052941-1|AAC35001.1| 370|Homo sapiens DAP-kinase related prot... 96 1e-19
AB018001-1|BAA88063.1| 370|Homo sapiens Death-associated protei... 96 1e-19
BC029511-1|AAH29511.1| 405|Homo sapiens STK4 protein protein. 95 2e-19
BC022515-1|AAH22515.1| 367|Homo sapiens testis-specific serine ... 95 2e-19
AY028964-1|AAK27734.1| 367|Homo sapiens testis-specific serine/... 95 2e-19
AB284522-1|BAF41973.1| 367|Homo sapiens testis-specific serine ... 95 2e-19
Z98752-7|CAI42315.1| 366|Homo sapiens serum/glucocorticoid regu... 95 2e-19
L07597-1|AAC82497.1| 735|Homo sapiens ribosomal protein S6 kina... 95 2e-19
BC114491-1|AAI14492.1| 1189|Homo sapiens NEK1 protein protein. 95 2e-19
BC017575-1|AAH17575.1| 476|Homo sapiens CHK1 checkpoint homolog... 95 2e-19
BC015147-1|AAH15147.1| 403|Homo sapiens Unknown (protein for IM... 95 2e-19
BC014966-1|AAH14966.1| 735|Homo sapiens ribosomal protein S6 ki... 95 2e-19
BC006106-1|AAH06106.3| 482|Homo sapiens ribosomal protein S6 ki... 95 2e-19
BC004202-1|AAH04202.1| 476|Homo sapiens CHEK1 protein protein. 95 2e-19
AL627313-6|CAI14649.1| 735|Homo sapiens ribosomal protein S6 ki... 95 2e-19
AK222581-1|BAD96301.1| 556|Homo sapiens 3-phosphoinositide depe... 95 2e-19
AF527555-1|AAM78553.1| 476|Homo sapiens CHK1 checkpoint homolog... 95 2e-19
AF032874-1|AAB88852.1| 476|Homo sapiens protein kinase protein. 95 2e-19
AF016582-1|AAC51736.1| 476|Homo sapiens Chk1 protein. 95 2e-19
AB067488-1|BAB67794.1| 1265|Homo sapiens KIAA1901 protein protein. 95 2e-19
AB032387-1|BAA84577.1| 476|Homo sapiens checkpoint kinase protein. 95 2e-19
AB019692-1|BAA85625.1| 889|Homo sapiens protein kinase PKNbeta ... 95 2e-19
Z92868-1|CAB07437.1| 686|Homo sapiens cGMP-dependent protein ki... 95 3e-19
Z92867-1|CAB07436.1| 671|Homo sapiens cGMP-dependent protein ki... 95 3e-19
Y07512-1|CAA68810.1| 686|Homo sapiens protein ( Human mRNA for ... 95 3e-19
X76104-1|CAA53712.1| 1431|Homo sapiens DAP-kinase protein. 95 3e-19
D45864-1|BAA08297.1| 671|Homo sapiens cGMP-dependent protein ki... 95 3e-19
DQ436495-1|ABD96827.1| 1430|Homo sapiens death-associated protei... 95 3e-19
BT006935-1|AAP35581.1| 367|Homo sapiens death-associated protei... 95 3e-19
BC127090-1|AAI27091.1| 686|Homo sapiens protein kinase, cGMP-de... 95 3e-19
BC113660-1|AAI13661.1| 1430|Homo sapiens death-associated protei... 95 3e-19
BC000094-1|AAH00094.3| 482|Homo sapiens ribosomal protein S6 ki... 95 3e-19
AL928686-2|CAI40743.1| 686|Homo sapiens protein kinase, cGMP-de... 95 3e-19
AL928686-1|CAI40742.1| 659|Homo sapiens protein kinase, cGMP-de... 95 3e-19
AL731537-3|CAI17115.1| 686|Homo sapiens protein kinase, cGMP-de... 95 3e-19
AL731537-2|CAI17114.1| 659|Homo sapiens protein kinase, cGMP-de... 95 3e-19
AL591852-1|CAH71696.1| 1455|Homo sapiens death-associated protei... 95 3e-19
AL391378-2|CAI39626.1| 686|Homo sapiens protein kinase, cGMP-de... 95 3e-19
AL391378-1|CAI39625.1| 659|Homo sapiens protein kinase, cGMP-de... 95 3e-19
AL161787-1|CAH73544.1| 1455|Homo sapiens death-associated protei... 95 3e-19
AL160279-1|CAI16306.1| 1455|Homo sapiens death-associated protei... 95 3e-19
AL157399-2|CAI41305.1| 686|Homo sapiens protein kinase, cGMP-de... 95 3e-19
AL157399-1|CAI41304.1| 659|Homo sapiens protein kinase, cGMP-de... 95 3e-19
AF099739-1|AAD20990.1| 482|Homo sapiens S6 kinase-related kinas... 95 3e-19
AF076931-1|AAD46063.1| 482|Homo sapiens serine/threonine kinase... 95 3e-19
AB208871-1|BAD92108.1| 1433|Homo sapiens Hypothetical protein DK... 95 3e-19
AB016869-1|BAA34402.1| 495|Homo sapiens p70 ribosomal S6 kinase... 95 3e-19
Z98049-1|CAI20579.1| 733|Homo sapiens ribosomal protein S6 kina... 94 4e-19
X85106-1|CAA59427.1| 733|Homo sapiens ribosomal S6 kinase protein. 94 4e-19
L07598-1|AAC82496.1| 540|Homo sapiens ribosomal protein S6 kina... 94 4e-19
BC002363-1|AAH02363.1| 733|Homo sapiens ribosomal protein S6 ki... 94 4e-19
AL022069-2|CAI19651.1| 733|Homo sapiens ribosomal protein S6 ki... 94 4e-19
AB209116-1|BAD92353.1| 806|Homo sapiens ribosomal protein S6 ki... 94 4e-19
CR456418-1|CAG30304.1| 586|Homo sapiens CHEK2 protein. 94 5e-19
BC038504-1|AAH38504.1| 783|Homo sapiens SNF1-like kinase protein. 94 5e-19
BC004207-1|AAH04207.1| 543|Homo sapiens CHK2 checkpoint homolog... 94 5e-19
AY800241-1|AAV41895.1| 543|Homo sapiens CHK2 checkpoint homolog... 94 5e-19
AY551303-1|AAS58464.1| 452|Homo sapiens protein kinase Chk2 tra... 94 5e-19
AY551297-1|AAS58458.1| 586|Homo sapiens protein kinase Chk2 tra... 94 5e-19
AL121825-1|CAH73823.1| 543|Homo sapiens CHK2 checkpoint homolog... 94 5e-19
AL117330-1|CAH73875.1| 543|Homo sapiens CHK2 checkpoint homolog... 94 5e-19
AK131076-1|BAC85126.1| 764|Homo sapiens FLJ00263 protein protein. 94 5e-19
AJ785968-1|CAH05056.1| 396|Homo sapiens PDPK2 protein protein. 94 5e-19
AJ131197-1|CAA10319.1| 543|Homo sapiens protein kinase protein. 94 5e-19
AF217975-1|AAG17218.1| 322|Homo sapiens unknown protein. 94 5e-19
AF174135-1|AAD48504.1| 543|Homo sapiens protein kinase CHK2 pro... 94 5e-19
AF096279-1|AAD11784.1| 543|Homo sapiens HuCds1 kinase protein. 94 5e-19
AF086904-1|AAC83693.1| 543|Homo sapiens protein kinase Chk2 pro... 94 5e-19
AB088047-1|BAC03375.1| 752|Homo sapiens microtubule affinity-re... 94 5e-19
AB049127-1|BAB39380.1| 688|Homo sapiens MAP/microtubule affinit... 94 5e-19
AB047786-1|BAD74070.1| 783|Homo sapiens serine/threonine protei... 94 5e-19
X85545-1|CAA59733.1| 358|Homo sapiens protein kinase protein. 93 7e-19
X80590-1|CAA56681.1| 387|Homo sapiens phosphorylase kinase prot... 93 7e-19
X07109-1|CAA30130.1| 673|Homo sapiens protein ( Human mRNA for ... 93 7e-19
X06318-1|CAA29634.1| 671|Homo sapiens protein ( Human mRNA for ... 93 7e-19
M13975-1|AAA60095.1| 673|Homo sapiens protein kinase C beta-II ... 93 7e-19
BC074753-1|AAH74753.1| 387|Homo sapiens phosphorylase kinase, g... 93 7e-19
BC069754-1|AAH69754.1| 387|Homo sapiens phosphorylase kinase, g... 93 7e-19
BC069738-1|AAH69738.1| 387|Homo sapiens phosphorylase kinase, g... 93 7e-19
BC069679-1|AAH69679.1| 387|Homo sapiens phosphorylase kinase, g... 93 7e-19
BC051327-1|AAH51327.1| 387|Homo sapiens phosphorylase kinase, g... 93 7e-19
BC041073-1|AAH41073.1| 358|Homo sapiens protein kinase, X-linke... 93 7e-19
BC036472-1|AAH36472.1| 673|Homo sapiens protein kinase C, beta ... 93 7e-19
BC026060-1|AAH26060.1| 541|Homo sapiens calcium/calmodulin-depe... 93 7e-19
AL928686-3|CAI40744.1| 283|Homo sapiens protein kinase, cGMP-de... 93 7e-19
AF321402-1|AAK91829.1| 588|Homo sapiens Ca2+/calmodulin-depende... 93 7e-19
AF321401-1|AAK91830.1| 533|Homo sapiens Ca2+/calmodulin-depende... 93 7e-19
AF321388-1|AAL37218.1| 498|Homo sapiens CaMKK beta 1 isoform pr... 93 7e-19
AF321387-1|AAL37217.1| 541|Homo sapiens CaMKK beta 1 isoform pr... 93 7e-19
AF321386-1|AAL37216.1| 545|Homo sapiens CaMKK beta 1 isoform pr... 93 7e-19
AF321385-1|AAL37215.1| 490|Homo sapiens CaMKK beta 2 isoform pr... 93 7e-19
AF287631-1|AAK64601.1| 533|Homo sapiens calcium/calmodulin-depe... 93 7e-19
AF287630-1|AAK64600.1| 588|Homo sapiens calcium/calmodulin-depe... 93 7e-19
AF254253-1|AAL36972.1| 387|Homo sapiens phosphorylase kinase ga... 93 7e-19
AF140507-1|AAD31507.1| 588|Homo sapiens Ca2+/calmodulin-depende... 93 7e-19
AF101264-1|AAD04566.1| 417|Homo sapiens Ca2+/calmodulin-depende... 93 7e-19
AC092101-3|AAS07453.1| 387|Homo sapiens unknown protein. 93 7e-19
AC002299-2|AAB97934.1| 496|Homo sapiens Protein kinase C beta (... 93 7e-19
AC002299-1|AAB97933.1| 494|Homo sapiens Protein kinase C beta (... 93 7e-19
AB081337-1|BAC19841.1| 498|Homo sapiens Ca2+/calmodulin-depende... 93 7e-19
AB081336-1|BAC19840.1| 541|Homo sapiens Ca2+/calmodulin-depende... 93 7e-19
AB018330-1|BAA34507.2| 557|Homo sapiens KIAA0787 protein protein. 93 7e-19
AY461663-1|AAS17971.1| 328|Homo sapiens testis-specific serine ... 93 9e-19
X61037-1|CAA43372.1| 417|Homo sapiens human protein kinase B p... 93 1e-18
U78876-1|AAB41729.1| 626|Homo sapiens MEK kinase 3 protein. 93 1e-18
EF560730-1|ABQ59040.1| 686|Homo sapiens PRKG1 protein protein. 93 1e-18
DQ454151-1|ABE11554.1| 622|Homo sapiens mitogen-activated prote... 93 1e-18
BC093674-1|AAH93674.1| 626|Homo sapiens mitogen-activated prote... 93 1e-18
BC093672-1|AAH93672.1| 626|Homo sapiens mitogen-activated prote... 93 1e-18
BC090859-1|AAH90859.1| 626|Homo sapiens mitogen-activated prote... 93 1e-18
BC008336-1|AAH08336.1| 594|Homo sapiens Unknown (protein for IM... 93 1e-18
AB209475-1|BAD92712.1| 461|Homo sapiens protein kinase C, alpha... 93 1e-18
CR536581-1|CAG38818.1| 429|Homo sapiens SGKL protein. 92 2e-18
BT020098-1|AAV38901.1| 367|Homo sapiens serum/glucocorticoid re... 92 2e-18
BC063885-1|AAH63885.1| 708|Homo sapiens NIMA (never in mitosis ... 92 2e-18
BC015326-1|AAH15326.1| 496|Homo sapiens serum/glucocorticoid re... 92 2e-18
AL139082-5|CAI12892.2| 708|Homo sapiens NIMA (never in mitosis ... 92 2e-18
AK223523-1|BAD97243.1| 496|Homo sapiens serum/glucocorticoid re... 92 2e-18
AF169035-1|AAF12758.1| 429|Homo sapiens protein kinase protein. 92 2e-18
AF085233-1|AAF27051.2| 496|Homo sapiens SGK-like protein SGKL p... 92 2e-18
X52479-1|CAA36718.1| 672|Homo sapiens protein ( Human PKC alpha... 92 2e-18
BC125272-1|AAI25273.1| 625|Homo sapiens MYO3A protein protein. 92 2e-18
BC119811-1|AAI19812.1| 664|Homo sapiens MYO3A protein protein. 92 2e-18
BC109274-1|AAI09275.1| 672|Homo sapiens protein kinase C, alpha... 92 2e-18
BC109273-1|AAI09274.1| 672|Homo sapiens protein kinase C, alpha... 92 2e-18
BC062616-1|AAH62616.1| 424|Homo sapiens protein serine kinase H... 92 2e-18
BC036079-1|AAH36079.1| 247|Homo sapiens MYO3A protein protein. 92 2e-18
AY633609-1|AAV33302.1| 672|Homo sapiens aging-associated gene 6... 92 2e-18
AY505125-1|AAS86443.1| 696|Homo sapiens protein kinase SAD-A pr... 92 2e-18
AY166857-1|AAN87839.1| 668|Homo sapiens serine/threonine protei... 92 2e-18
AY101367-1|AAM34500.1| 1616|Homo sapiens myosin IIIA protein. 92 2e-18
AL391812-1|CAI17380.1| 1616|Homo sapiens myosin IIIA protein. 92 2e-18
AL360217-1|CAD13206.2| 1616|Homo sapiens myosin IIIA protein. 92 2e-18
AL358612-3|CAH73816.1| 247|Homo sapiens myosin IIIA protein. 92 2e-18
AL358612-1|CAH73814.1| 1616|Homo sapiens myosin IIIA protein. 92 2e-18
AL162503-4|CAH73661.1| 1616|Homo sapiens myosin IIIA protein. 92 2e-18
AK131534-1|BAD18671.1| 766|Homo sapiens protein ( Homo sapiens ... 92 2e-18
AJ272212-1|CAB91984.1| 424|Homo sapiens protein serine kinase p... 92 2e-18
AF533880-1|AAP97727.1| 674|Homo sapiens putative serine/threoni... 92 2e-18
AF533879-1|AAP97726.1| 736|Homo sapiens putative serine/threoni... 92 2e-18
AF533878-1|AAP97725.1| 674|Homo sapiens putative serine/threoni... 92 2e-18
AF533877-1|AAP97724.1| 674|Homo sapiens putative serine/threoni... 92 2e-18
AF533876-1|AAP97723.1| 668|Homo sapiens putative serine/threoni... 92 2e-18
AF229172-1|AAF70861.1| 1615|Homo sapiens class III myosin protein. 92 2e-18
Z98752-8|CAC18509.1| 367|Homo sapiens serum/glucocorticoid regu... 91 3e-18
Z98752-5|CAI42312.1| 427|Homo sapiens serum/glucocorticoid regu... 91 3e-18
X65293-1|CAA46388.1| 737|Homo sapiens protein kinase C epsilon... 91 3e-18
BC109034-1|AAI09035.1| 737|Homo sapiens protein kinase C, epsil... 91 3e-18
BC109033-1|AAI09034.1| 737|Homo sapiens protein kinase C, epsil... 91 3e-18
BC065511-1|AAH65511.1| 367|Homo sapiens SGK2 protein protein. 91 3e-18
BC035745-1|AAH35745.1| 385|Homo sapiens calcium/calmodulin-depe... 91 3e-18
BC027464-1|AAH27464.1| 403|Homo sapiens aurora kinase A protein. 91 3e-18
BC014037-1|AAH14037.3| 367|Homo sapiens serum/glucocorticoid re... 91 3e-18
BC006423-1|AAH06423.1| 403|Homo sapiens aurora kinase A protein. 91 3e-18
BC002499-1|AAH02499.1| 403|Homo sapiens AURKA protein protein. 91 3e-18
BC001280-1|AAH01280.1| 403|Homo sapiens aurora kinase A protein. 91 3e-18
BC000318-1|AAH00318.2| 266|Homo sapiens CAMKK2 protein protein. 91 3e-18
AY987010-1|AAX88805.1| 393|Homo sapiens serum/glucocorticoid re... 91 3e-18
AL731559-2|CAI14675.1| 385|Homo sapiens calcium/calmodulin-depe... 91 3e-18
AL731559-1|CAI14674.1| 357|Homo sapiens calcium/calmodulin-depe... 91 3e-18
AL512783-2|CAH74036.1| 385|Homo sapiens calcium/calmodulin-depe... 91 3e-18
AL512783-1|CAH74035.1| 357|Homo sapiens calcium/calmodulin-depe... 91 3e-18
AL512284-2|CAH71694.1| 385|Homo sapiens calcium/calmodulin-depe... 91 3e-18
AL512284-1|CAH71693.1| 357|Homo sapiens calcium/calmodulin-depe... 91 3e-18
AL391314-2|CAI14410.1| 385|Homo sapiens calcium/calmodulin-depe... 91 3e-18
AL391314-1|CAI14409.1| 357|Homo sapiens calcium/calmodulin-depe... 91 3e-18
AL121914-4|CAM45838.1| 347|Homo sapiens aurora kinase A protein. 91 3e-18
AL121914-3|CAC12717.1| 403|Homo sapiens aurora kinase A protein. 91 3e-18
AF286366-1|AAG00534.1| 357|Homo sapiens CamKI-like protein kina... 91 3e-18
AF195947-1|AAF29508.1| 403|Homo sapiens STK15 serine/threonine ... 91 3e-18
AF186470-1|AAG17012.1| 427|Homo sapiens protein kinase protein. 91 3e-18
AF169034-1|AAF12757.2| 367|Homo sapiens protein kinase protein. 91 3e-18
AF011468-1|AAC63902.1| 403|Homo sapiens serine/threonine kinase... 91 3e-18
AF008551-1|AAC12708.1| 403|Homo sapiens aurora-related kinase 1... 91 3e-18
AB081726-1|BAC19846.1| 385|Homo sapiens CaM-kinase I delta prot... 91 3e-18
Z15114-1|CAA78820.1| 536|Homo sapiens protein kinase C gamma pr... 91 4e-18
BC047876-1|AAH47876.1| 697|Homo sapiens protein kinase C, gamma... 91 4e-18
AY505124-1|AAS86442.1| 778|Homo sapiens protein kinase SAD-B pr... 91 4e-18
AY458602-1|AAS10354.1| 778|Homo sapiens SAD1 kinase protein. 91 4e-18
AL450063-12|CAI16855.1| 321|Homo sapiens protein kinase, cAMP-d... 91 4e-18
AL358612-2|CAH73815.1| 197|Homo sapiens myosin IIIA protein. 91 4e-18
AF479827-1|AAL87698.1| 778|Homo sapiens protein kinase-like pro... 91 4e-18
AF479826-1|AAL87697.1| 794|Homo sapiens putative serine/threoni... 91 4e-18
AF345987-1|AAK13533.1| 697|Homo sapiens protein kinase C gamma ... 91 4e-18
AB058714-1|BAB47440.1| 715|Homo sapiens KIAA1811 protein protein. 91 4e-18
Y16106-1|CAA76073.1| 734|Homo sapiens cGMP-dependant protein ki... 91 5e-18
Y15801-1|CAA75792.1| 277|Homo sapiens protein kinase protein. 91 5e-18
Y13927-1|CAA74244.1| 277|Homo sapiens protein kinase protein. 91 5e-18
X94612-1|CAA64318.1| 762|Homo sapiens Type II cGMP-dependent pr... 91 5e-18
U60206-1|AAB17261.1| 491|Homo sapiens serine/threonine protein ... 91 5e-18
U26424-1|AAC50386.1| 491|Homo sapiens MST2 protein. 91 5e-18
BC074852-1|AAH74852.1| 277|Homo sapiens protein kinase, Y-linke... 91 5e-18
BC074851-1|AAH74851.1| 277|Homo sapiens protein kinase, Y-linke... 91 5e-18
BC010640-1|AAH10640.1| 491|Homo sapiens serine/threonine kinase... 91 5e-18
X85337-1|CAA59685.1| 991|Homo sapiens myosin light chain kinase... 90 6e-18
L41816-1|AAA99458.1| 370|Homo sapiens cam kinase I protein. 90 6e-18
BC106755-1|AAI06756.1| 370|Homo sapiens calcium/calmodulin-depe... 90 6e-18
BC106754-1|AAI06755.1| 370|Homo sapiens calcium/calmodulin-depe... 90 6e-18
U22456-1|AAA64850.1| 174|Homo sapiens AMP-activated protein kin... 90 9e-18
BC037303-1|AAH37303.1| 550|Homo sapiens PRKAA1 protein protein. 90 9e-18
BC012622-1|AAH12622.1| 207|Homo sapiens PRKAA1 protein protein. 90 9e-18
AL450063-8|CAI16851.1| 206|Homo sapiens protein kinase, cAMP-de... 90 9e-18
AB022017-1|BAA36547.1| 550|Homo sapiens AMP-activated protein k... 90 9e-18
U66464-1|AAB97983.1| 833|Homo sapiens hematopoietic progenitor ... 89 1e-17
M55284-1|AAA60100.1| 682|Homo sapiens protein kinase C-L protein. 89 1e-17
BC037268-1|AAH37268.1| 683|Homo sapiens protein kinase C, eta p... 89 1e-17
BC045538-1|AAH45538.1| 247|Homo sapiens MYO3A protein protein. 89 1e-17
BC032787-1|AAH32787.1| 476|Homo sapiens calcium/calmodulin-depe... 89 1e-17
BC028587-1|AAH28587.1| 482|Homo sapiens NEK11 protein protein. 89 1e-17
AY212935-1|AAP29964.1| 460|Homo sapiens CLICK III protein. 89 1e-17
AL049688-1|CAB41259.1| 481|Homo sapiens hypothetical protein pr... 89 1e-17
AL023754-3|CAI19991.1| 476|Homo sapiens calcium/calmodulin-depe... 89 1e-17
AF428261-1|AAL28100.1| 476|Homo sapiens calcium/calmodulin-depe... 89 1e-17
AB071997-1|BAC06351.1| 470|Homo sapiens NIMA-related kinase 11S... 89 1e-17
AB071996-1|BAC06350.1| 645|Homo sapiens NIMA-related kinase 11L... 89 1e-17
BC031647-1|AAH31647.1| 520|Homo sapiens calcium/calmodulin-depe... 84 2e-17
D84212-1|BAA23592.1| 402|Homo sapiens aurora/IPL1-related kinas... 89 2e-17
D70899-1|BAA18934.1| 762|Homo sapiens cGMP-dependent protein ki... 89 2e-17
AY098866-1|AAM21719.1| 486|Homo sapiens PKE protein kinase prot... 89 2e-17
AL590105-1|CAI13011.1| 486|Homo sapiens protein kinase (PKE) pr... 89 2e-17
AL512622-1|CAI12181.1| 486|Homo sapiens protein kinase (PKE) pr... 89 2e-17
Z29067-1|CAA82310.1| 459|Homo sapiens protein kinase protein. 88 3e-17
M60725-1|AAA36411.1| 502|Homo sapiens p70 ribosomal S6 kinase a... 88 3e-17
M60724-1|AAA36410.1| 525|Homo sapiens p70 ribosomal S6 kinase a... 88 3e-17
BC056423-1|AAH56423.1| 214|Homo sapiens ULK3 protein protein. 88 3e-17
BC053365-1|AAH53365.1| 451|Homo sapiens RPS6KB1 protein protein. 88 3e-17
BC036117-1|AAH36117.1| 214|Homo sapiens ULK3 protein protein. 88 3e-17
AK075004-1|BAC11348.1| 423|Homo sapiens protein ( Homo sapiens ... 88 3e-17
AF239798-1|AAF63496.1| 619|Homo sapiens protein kinase MEKK2b p... 88 3e-17
AC110926-2|AAY15070.1| 270|Homo sapiens unknown protein. 88 3e-17
AB208963-1|BAD92200.1| 621|Homo sapiens Protein kinase MEKK2b v... 88 3e-17
AB051552-1|BAB21856.1| 608|Homo sapiens KIAA1765 protein protein. 88 3e-17
L07861-1|AAA03175.1| 676|Homo sapiens protein kinase C-delta 13... 88 3e-17
L07860-1|AAA03176.1| 676|Homo sapiens protein kinase C-delta 13... 88 3e-17
D10495-1|BAA01381.1| 626|Homo sapiens protein kinase C delta-ty... 88 3e-17
BC111088-1|AAI11089.1| 252|Homo sapiens TSSK4 protein protein. 88 3e-17
BC075064-1|AAH75064.2| 275|Homo sapiens AURKC protein protein. 88 3e-17
BC069655-1|AAH69655.1| 390|Homo sapiens PHKG1 protein protein. 88 3e-17
BC043350-1|AAH43350.1| 676|Homo sapiens protein kinase C, delta... 88 3e-17
BC038238-1|AAH38238.1| 414|Homo sapiens serine/threonine kinase... 88 3e-17
AY714054-1|AAU04399.1| 306|Homo sapiens aurora-C protein. 88 3e-17
AY661554-1|AAT64422.1| 290|Homo sapiens aurora/Ipl1-related kin... 88 3e-17
AP001751-1|BAA95536.1| 786|Homo sapiens SNF1LK protein. 88 3e-17
AJ250839-1|CAB76471.1| 414|Homo sapiens serine/threonine protei... 88 3e-17
AB017332-1|BAA76292.1| 309|Homo sapiens Aurora/Ipl1-related kin... 88 3e-17
X90870-1|CAA62378.1| 458|Homo sapiens myosin-light-chain kinase... 87 5e-17
U48959-1|AAC18423.2| 1914|Homo sapiens myosin light chain kinase... 87 5e-17
AY339601-1|AAQ02673.1| 1914|Homo sapiens long myosin light chain... 87 5e-17
AF069601-1|AAD15921.2| 1845|Homo sapiens myosin light chain kina... 87 5e-17
AB037663-1|BAB21504.1| 992|Homo sapiens myosin light chain kina... 87 5e-17
CR536566-1|CAG38803.1| 745|Homo sapiens RPS6KA6 protein. 87 6e-17
BC126182-1|AAI26183.1| 385|Homo sapiens protein serine kinase H... 87 6e-17
BC126180-1|AAI26181.1| 385|Homo sapiens protein serine kinase H... 87 6e-17
BC112101-1|AAI12102.1| 979|Homo sapiens NIMA related kinase 9 p... 87 6e-17
BC093881-1|AAH93881.1| 979|Homo sapiens NIMA (never in mitosis ... 87 6e-17
AY080896-1|AAL87410.1| 979|Homo sapiens NIMA-family kinase NERC... 87 6e-17
AY048580-1|AAL05428.1| 979|Homo sapiens NIMA-related kinase Nek... 87 6e-17
AY037806-1|AAK59985.1| 385|Homo sapiens serine/threonine kinase... 87 6e-17
AL389887-1|CAC16111.2| 745|Homo sapiens ribosomal protein S6 ki... 87 6e-17
AL354653-1|CAD13486.2| 745|Homo sapiens ribosomal protein S6 ki... 87 6e-17
AF184965-1|AAF13190.1| 745|Homo sapiens ribosomal S6 kinase pro... 87 6e-17
AF059681-1|AAC77369.1| 275|Homo sapiens serine/threonine kinase... 87 6e-17
AC007055-5|AAD31940.1| 312|Homo sapiens protein ( Homo sapiens ... 87 6e-17
AB082526-1|BAC02704.1| 1011|Homo sapiens KIAA1995 protein protein. 87 6e-17
AC005581-1|AAC33487.1| 462|Homo sapiens R31237_1, partial CDS p... 73 7e-17
BC128510-1|AAI28511.1| 1203|Homo sapiens KIAA0999 protein protein. 86 1e-16
BC034988-1|AAH34988.1| 1036|Homo sapiens ULK2 protein protein. 86 1e-16
AF111105-1|AAD28547.1| 618|Homo sapiens mitogen-activated prote... 86 1e-16
AF069603-1|AAD15923.1| 1793|Homo sapiens myosin light chain kina... 86 1e-16
AF069602-1|AAD15922.1| 1862|Homo sapiens myosin light chain kina... 86 1e-16
AF054621-1|AAC25955.1| 309|Homo sapiens serine/threonine kinase... 86 1e-16
AF045458-1|AAC32326.1| 1050|Homo sapiens serine/threonine kinase... 86 1e-16
AB023216-1|BAA76843.2| 1371|Homo sapiens KIAA0999 protein protein. 86 1e-16
AB018265-1|BAA34442.2| 1066|Homo sapiens KIAA0722 protein protein. 86 1e-16
AB014523-1|BAA31598.2| 1100|Homo sapiens KIAA0623 protein protein. 86 1e-16
U06454-1|AAA64745.1| 552|Homo sapiens AMP-activated protein kin... 86 1e-16
EF056019-1|ABK30810.1| 552|Homo sapiens AMP-activated alpha 2 s... 86 1e-16
BT019534-1|AAV38341.1| 344|Homo sapiens serine/threonine kinase... 86 1e-16
BC080581-1|AAH80581.1| 344|Homo sapiens aurora kinase B protein. 86 1e-16
BC069823-1|AAH69823.1| 552|Homo sapiens AMP-activated protein k... 86 1e-16
BC069740-1|AAH69740.1| 552|Homo sapiens AMP-activated protein k... 86 1e-16
BC069680-1|AAH69680.1| 552|Homo sapiens protein kinase, AMP-act... 86 1e-16
BC036422-1|AAH36422.1| 436|Homo sapiens hypothetical protein MG... 86 1e-16
BC013300-1|AAH13300.2| 371|Homo sapiens AURKB protein protein. 86 1e-16
BC009751-1|AAH09751.1| 344|Homo sapiens aurora kinase B protein. 86 1e-16
BC000442-1|AAH00442.3| 344|Homo sapiens aurora kinase B protein. 86 1e-16
AL035705-2|CAC17574.2| 552|Homo sapiens protein kinase, AMP-act... 86 1e-16
AF008552-1|AAC12709.1| 344|Homo sapiens aurora-related kinase 2... 86 1e-16
AB011450-1|BAA32136.1| 344|Homo sapiens aurora and IPL1-like mi... 86 1e-16
AB011446-1|BAA82709.1| 343|Homo sapiens Aik2 protein. 86 1e-16
U63973-1|AAB05929.1| 563|Homo sapiens rhodopsin kinase protein. 85 2e-16
L77503-1|AAG50439.1| 563|Homo sapiens rhodopsin kinase protein. 85 2e-16
L77502-1|AAT00534.2| 563|Homo sapiens rhodopsin kinase protein. 85 2e-16
L20321-1|AAA36658.1| 841|Homo sapiens protein serine/threonine ... 85 2e-16
BC063044-1|AAH63044.1| 781|Homo sapiens NEK4 protein protein. 85 2e-16
BC015515-1|AAH15515.1| 451|Homo sapiens Unknown (protein for IM... 85 2e-16
D79997-1|BAA11492.2| 656|Homo sapiens KIAA0175 protein. 85 2e-16
BC040457-1|AAH40457.1| 478|Homo sapiens calcium/calmodulin-depe... 85 2e-16
BC014039-1|AAH14039.1| 651|Homo sapiens maternal embryonic leuc... 85 2e-16
AL442063-1|CAI16995.2| 651|Homo sapiens maternal embryonic leuc... 85 2e-16
AL354932-1|CAI11034.2| 651|Homo sapiens maternal embryonic leuc... 85 2e-16
AK222811-1|BAD96531.1| 651|Homo sapiens maternal embryonic leuc... 85 2e-16
AJ006701-1|CAA07196.1| 603|Homo sapiens putative serine/threoni... 85 2e-16
AF145711-1|AAD30559.1| 489|Homo sapiens calcium/calmodulin-depe... 85 2e-16
AF145710-1|AAD30558.1| 478|Homo sapiens calcium/calmodulin-depe... 85 2e-16
AF091486-1|AAD55815.1| 478|Homo sapiens calmodulin-dependent pr... 85 2e-16
AB023185-1|BAA76812.1| 527|Homo sapiens KIAA0968 protein protein. 85 2e-16
U66064-1|AAB80848.1| 315|Homo sapiens calcium/calmodulin-depend... 85 3e-16
EF560744-1|ABQ59054.1| 841|Homo sapiens NEK4 protein protein. 85 3e-16
BC071579-1|AAH71579.1| 873|Homo sapiens MAP4K3 protein protein. 85 3e-16
AL713896-5|CAI13790.1| 529|Homo sapiens calcium/calmodulin-depe... 85 3e-16
AL713896-4|CAI13789.1| 495|Homo sapiens calcium/calmodulin-depe... 85 3e-16
AL713896-3|CAI13791.1| 527|Homo sapiens calcium/calmodulin-depe... 85 3e-16
AL713896-2|CAI13788.1| 516|Homo sapiens calcium/calmodulin-depe... 85 3e-16
AL596247-5|CAI13965.1| 529|Homo sapiens calcium/calmodulin-depe... 85 3e-16
>L19559-1|AAA36659.1| 603|Homo sapiens protein kinase protein.
Length = 603
Score = 264 bits (647), Expect = 2e-70
Identities = 114/181 (62%), Positives = 146/181 (80%)
Frame = +1
Query: 184 DPQTNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIH 363
DP++ Y R RF GKGGFAKC+EI D+ + +++AG EKM+ EISIH
Sbjct: 46 DPRSRRRYVRGRFLGKGGFAKCFEISDVDTKEVFAGKIVPKSLLLKPHQREKMSMEISIH 105
Query: 364 RSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQ 543
RSL H+HVVGFH FFED+ ++++LELC++RS++ELHKRRKA+TEPE R+Y+ QI+LG Q
Sbjct: 106 RSLAHQHVVGFHGFFEDNDFVFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIVLGCQ 165
Query: 544 YLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTK 723
YLH R+IHRDLKLGNLFL++DL VKIGDFGLA ++EY+GERK+TLCGTPNYIAPE+L+K
Sbjct: 166 YLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEYDGERKKTLCGTPNYIAPEVLSK 225
Query: 724 K 726
K
Sbjct: 226 K 226
>X73458-1|CAA51837.1| 603|Homo sapiens protein kinase protein.
Length = 603
Score = 262 bits (643), Expect = 7e-70
Identities = 114/181 (62%), Positives = 145/181 (80%)
Frame = +1
Query: 184 DPQTNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIH 363
DP++ Y R RF GKGGFAKC+EI D + +++AG EKM+ EISIH
Sbjct: 46 DPRSRRRYVRGRFLGKGGFAKCFEISDADTKEVFAGKIVPKSLLLKPHQREKMSMEISIH 105
Query: 364 RSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQ 543
RSL H+HVVGFH FFED+ ++++LELC++RS++ELHKRRKA+TEPE R+Y+ QI+LG Q
Sbjct: 106 RSLAHQHVVGFHGFFEDNDFVFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIVLGCQ 165
Query: 544 YLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTK 723
YLH R+IHRDLKLGNLFL++DL VKIGDFGLA ++EY+GERK+TLCGTPNYIAPE+L+K
Sbjct: 166 YLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEYDGERKKTLCGTPNYIAPEVLSK 225
Query: 724 K 726
K
Sbjct: 226 K 226
>BC014846-1|AAH14846.1| 603|Homo sapiens polo-like kinase 1
(Drosophila) protein.
Length = 603
Score = 262 bits (643), Expect = 7e-70
Identities = 114/181 (62%), Positives = 145/181 (80%)
Frame = +1
Query: 184 DPQTNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIH 363
DP++ Y R RF GKGGFAKC+EI D + +++AG EKM+ EISIH
Sbjct: 46 DPRSRRRYVRGRFLGKGGFAKCFEISDADTKEVFAGKIVPKSLLLKPHQREKMSMEISIH 105
Query: 364 RSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQ 543
RSL H+HVVGFH FFED+ ++++LELC++RS++ELHKRRKA+TEPE R+Y+ QI+LG Q
Sbjct: 106 RSLAHQHVVGFHGFFEDNDFVFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIVLGCQ 165
Query: 544 YLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTK 723
YLH R+IHRDLKLGNLFL++DL VKIGDFGLA ++EY+GERK+TLCGTPNYIAPE+L+K
Sbjct: 166 YLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEYDGERKKTLCGTPNYIAPEVLSK 225
Query: 724 K 726
K
Sbjct: 226 K 226
>BC003002-1|AAH03002.1| 603|Homo sapiens polo-like kinase 1
(Drosophila) protein.
Length = 603
Score = 262 bits (643), Expect = 7e-70
Identities = 114/181 (62%), Positives = 145/181 (80%)
Frame = +1
Query: 184 DPQTNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIH 363
DP++ Y R RF GKGGFAKC+EI D + +++AG EKM+ EISIH
Sbjct: 46 DPRSRRRYVRGRFLGKGGFAKCFEISDADTKEVFAGKIVPKSLLLKPHQREKMSMEISIH 105
Query: 364 RSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQ 543
RSL H+HVVGFH FFED+ ++++LELC++RS++ELHKRRKA+TEPE R+Y+ QI+LG Q
Sbjct: 106 RSLAHQHVVGFHGFFEDNDFVFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIVLGCQ 165
Query: 544 YLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTK 723
YLH R+IHRDLKLGNLFL++DL VKIGDFGLA ++EY+GERK+TLCGTPNYIAPE+L+K
Sbjct: 166 YLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEYDGERKKTLCGTPNYIAPEVLSK 225
Query: 724 K 726
K
Sbjct: 226 K 226
>BC002369-1|AAH02369.1| 603|Homo sapiens polo-like kinase 1
(Drosophila) protein.
Length = 603
Score = 262 bits (643), Expect = 7e-70
Identities = 114/181 (62%), Positives = 145/181 (80%)
Frame = +1
Query: 184 DPQTNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIH 363
DP++ Y R RF GKGGFAKC+EI D + +++AG EKM+ EISIH
Sbjct: 46 DPRSRRRYVRGRFLGKGGFAKCFEISDADTKEVFAGKIVPKSLLLKPHQREKMSMEISIH 105
Query: 364 RSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQ 543
RSL H+HVVGFH FFED+ ++++LELC++RS++ELHKRRKA+TEPE R+Y+ QI+LG Q
Sbjct: 106 RSLAHQHVVGFHGFFEDNDFVFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIVLGCQ 165
Query: 544 YLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTK 723
YLH R+IHRDLKLGNLFL++DL VKIGDFGLA ++EY+GERK+TLCGTPNYIAPE+L+K
Sbjct: 166 YLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEYDGERKKTLCGTPNYIAPEVLSK 225
Query: 724 K 726
K
Sbjct: 226 K 226
>X75932-1|CAA53536.1| 603|Homo sapiens Serine/Threonine protein
kinase protein.
Length = 603
Score = 260 bits (636), Expect = 5e-69
Identities = 113/181 (62%), Positives = 144/181 (79%)
Frame = +1
Query: 184 DPQTNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIH 363
DP++ Y R RF GKGGFAKC+EI D + +++AG EKM+ EISIH
Sbjct: 46 DPRSRRRYVRGRFLGKGGFAKCFEISDADTKEVFAGKIVPKSLLLKPHQREKMSMEISIH 105
Query: 364 RSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQ 543
RSL H+HVVGFH FFED+ ++++LELC++RS++E HKRRKA+TEPE R+Y+ QI+LG Q
Sbjct: 106 RSLAHQHVVGFHGFFEDNDFVFVVLELCRRRSLLEPHKRRKALTEPEARYYLRQIVLGCQ 165
Query: 544 YLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTK 723
YLH R+IHRDLKLGNLFL++DL VKIGDFGLA ++EY+GERK+TLCGTPNYIAPE+L+K
Sbjct: 166 YLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEYDGERKKTLCGTPNYIAPEVLSK 225
Query: 724 K 726
K
Sbjct: 226 K 226
>U01038-1|AAA56634.1| 603|Homo sapiens pLK protein.
Length = 603
Score = 258 bits (631), Expect = 2e-68
Identities = 112/181 (61%), Positives = 143/181 (79%)
Frame = +1
Query: 184 DPQTNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIH 363
DP++ Y R R KGGFAKC+EI D + +++AG EKM+ EISIH
Sbjct: 46 DPRSRRRYVRGRLLSKGGFAKCFEISDADTKEVFAGKIVPKSLLLKPHQREKMSMEISIH 105
Query: 364 RSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQ 543
RSL H+HVVGFH FFED+ ++++LELC++RS++ELHKRRKA+TEPE R+Y+ QI+LG Q
Sbjct: 106 RSLAHQHVVGFHGFFEDNDFVFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIVLGCQ 165
Query: 544 YLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTK 723
YLH R+IHRDLKLGNLFL++DL VKIGDFGLA ++EY+GERK+TLCGTPNYIAPE+L+K
Sbjct: 166 YLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEYDGERKKTLCGTPNYIAPEVLSK 225
Query: 724 K 726
K
Sbjct: 226 K 226
>AB084459-1|BAD93352.1| 247|Homo sapiens polo-like kinase 1 delta
protein.
Length = 247
Score = 254 bits (622), Expect = 2e-67
Identities = 110/177 (62%), Positives = 140/177 (79%)
Frame = +1
Query: 184 DPQTNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIH 363
DP++ Y R RF GKGGFAKC+EI D + +++AG EKM+ EISIH
Sbjct: 46 DPRSRRRYVRGRFLGKGGFAKCFEISDADTKEVFAGKIVPKSLLLKPHQREKMSMEISIH 105
Query: 364 RSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQ 543
RSL H+HVVGFH FFED+ ++++LELC++RS++ELHKRRKA+TEPE R+Y+ QI+LG Q
Sbjct: 106 RSLAHQHVVGFHGFFEDNDFVFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIVLGCQ 165
Query: 544 YLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEI 714
YLH R+IHRDLKLGNLFL++DL VKIGDFGLA ++EY+GERK+TLCGTPNYIAP +
Sbjct: 166 YLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEYDGERKKTLCGTPNYIAPAV 222
>BC013879-1|AAH13879.1| 685|Homo sapiens polo-like kinase 2
(Drosophila) protein.
Length = 685
Score = 214 bits (522), Expect = 3e-55
Identities = 92/181 (50%), Positives = 128/181 (70%)
Frame = +1
Query: 184 DPQTNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIH 363
DP T Y R + GKGGFAKCYE+ D+ +N++YA EK+ +EI +H
Sbjct: 75 DPTTGKRYCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELH 134
Query: 364 RSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQ 543
R L HKHVV F+ +FED NIYI+LE C +RSM + K RK +TEPE R+Y+ QI+ G++
Sbjct: 135 RILHHKHVVQFYHYFEDKENIYILLEYCSRRSMAHILKARKVLTEPEVRYYLRQIVSGLK 194
Query: 544 YLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTK 723
YLH + I+HRDLKLGN F+++ + +K+GDFGLAAR+E R++T+CGTPNY++PE+L K
Sbjct: 195 YLHEQEILHRDLKLGNFFINEAMELKVGDFGLAARLEPLEHRRRTICGTPNYLSPEVLNK 254
Query: 724 K 726
+
Sbjct: 255 Q 255
>AK098163-1|BAC05247.1| 372|Homo sapiens protein ( Homo sapiens
cDNA FLJ40844 fis, clone TRACH2014356, highly similar to
SERINE/THREONINE-PROTEIN KINASE SNK (EC 2.7.1.-). ).
Length = 372
Score = 214 bits (522), Expect = 3e-55
Identities = 92/181 (50%), Positives = 128/181 (70%)
Frame = +1
Query: 184 DPQTNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIH 363
DP T Y R + GKGGFAKCYE+ D+ +N++YA EK+ +EI +H
Sbjct: 68 DPTTGKRYCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELH 127
Query: 364 RSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQ 543
R L HKHVV F+ +FED NIYI+LE C +RSM + K RK +TEPE R+Y+ QI+ G++
Sbjct: 128 RILHHKHVVQFYHYFEDKENIYILLEYCSRRSMAHILKARKVLTEPEVRYYLRQIVSGLK 187
Query: 544 YLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTK 723
YLH + I+HRDLKLGN F+++ + +K+GDFGLAAR+E R++T+CGTPNY++PE+L K
Sbjct: 188 YLHEQEILHRDLKLGNFFINEAMELKVGDFGLAARLEPLEHRRRTICGTPNYLSPEVLNK 247
Query: 724 K 726
+
Sbjct: 248 Q 248
>AF223574-1|AAF62897.1| 685|Homo sapiens serum-inducible kinase
protein.
Length = 685
Score = 214 bits (522), Expect = 3e-55
Identities = 92/181 (50%), Positives = 128/181 (70%)
Frame = +1
Query: 184 DPQTNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIH 363
DP T Y R + GKGGFAKCYE+ D+ +N++YA EK+ +EI +H
Sbjct: 75 DPTTGKRYCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELH 134
Query: 364 RSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQ 543
R L HKHVV F+ +FED NIYI+LE C +RSM + K RK +TEPE R+Y+ QI+ G++
Sbjct: 135 RILHHKHVVQFYHYFEDKENIYILLEYCSRRSMAHILKARKVLTEPEVRYYLRQIVSGLK 194
Query: 544 YLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTK 723
YLH + I+HRDLKLGN F+++ + +K+GDFGLAAR+E R++T+CGTPNY++PE+L K
Sbjct: 195 YLHEQEILHRDLKLGNFFINEAMELKVGDFGLAARLEPLEHRRRTICGTPNYLSPEVLNK 254
Query: 724 K 726
+
Sbjct: 255 Q 255
>AF059617-1|AAC14573.1| 685|Homo sapiens serum-inducible kinase
protein.
Length = 685
Score = 214 bits (522), Expect = 3e-55
Identities = 92/181 (50%), Positives = 128/181 (70%)
Frame = +1
Query: 184 DPQTNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIH 363
DP T Y R + GKGGFAKCYE+ D+ +N++YA EK+ +EI +H
Sbjct: 75 DPTTGKRYCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELH 134
Query: 364 RSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQ 543
R L HKHVV F+ +FED NIYI+LE C +RSM + K RK +TEPE R+Y+ QI+ G++
Sbjct: 135 RILHHKHVVQFYHYFEDKENIYILLEYCSRRSMAHILKARKVLTEPEVRYYLRQIVSGLK 194
Query: 544 YLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTK 723
YLH + I+HRDLKLGN F+++ + +K+GDFGLAAR+E R++T+CGTPNY++PE+L K
Sbjct: 195 YLHEQEILHRDLKLGNFFINEAMELKVGDFGLAARLEPLEHRRRTICGTPNYLSPEVLNK 254
Query: 724 K 726
+
Sbjct: 255 Q 255
>U56998-1|AAC50637.1| 607|Homo sapiens putative serine/threonine
protein kinase PRK protein.
Length = 607
Score = 203 bits (496), Expect = 4e-52
Identities = 88/181 (48%), Positives = 123/181 (67%)
Frame = +1
Query: 184 DPQTNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIH 363
DP++ TY + R GKGGFA+CYE D + YA EK+ EI +H
Sbjct: 16 DPRSGRTYLKGRLLGKGGFARCYEATDTETGSAYAVKVIPQSRVAKPHQREKILNEIELH 75
Query: 364 RSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQ 543
R LQH+H+V F FED+ NIYI LELC ++S+ + K R + EPE R+Y+ QIL G++
Sbjct: 76 RDLQHRHIVRFSHHFEDADNIYIFLELCSRKSLAHIWKARHTLLEPEVRYYLRQILSGLK 135
Query: 544 YLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTK 723
YLH + I+HRDLKLGN F+ +++ +K+GDFGLAAR+E +RK+T+CGTPNY+APE+L +
Sbjct: 136 YLHQRGILHRDLKLGNFFITENMELKVGDFGLAARLEPPEQRKKTICGTPNYVAPEVLLR 195
Query: 724 K 726
+
Sbjct: 196 Q 196
>BC013899-1|AAH13899.1| 646|Homo sapiens polo-like kinase 3
(Drosophila) protein.
Length = 646
Score = 203 bits (496), Expect = 4e-52
Identities = 88/181 (48%), Positives = 123/181 (67%)
Frame = +1
Query: 184 DPQTNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIH 363
DP++ TY + R GKGGFA+CYE D + YA EK+ EI +H
Sbjct: 55 DPRSGRTYLKGRLLGKGGFARCYEATDTETGSAYAVKVIPQSRVAKPHQREKILNEIELH 114
Query: 364 RSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQ 543
R LQH+H+V F FED+ NIYI LELC ++S+ + K R + EPE R+Y+ QIL G++
Sbjct: 115 RDLQHRHIVRFSHHFEDADNIYIFLELCSRKSLAHIWKARHTLLEPEVRYYLRQILSGLK 174
Query: 544 YLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTK 723
YLH + I+HRDLKLGN F+ +++ +K+GDFGLAAR+E +RK+T+CGTPNY+APE+L +
Sbjct: 175 YLHQRGILHRDLKLGNFFITENMELKVGDFGLAARLEPPEQRKKTICGTPNYVAPEVLLR 234
Query: 724 K 726
+
Sbjct: 235 Q 235
>AY764184-1|AAU88146.1| 646|Homo sapiens polo-like kinase 3
(Drosophila) protein.
Length = 646
Score = 203 bits (496), Expect = 4e-52
Identities = 88/181 (48%), Positives = 123/181 (67%)
Frame = +1
Query: 184 DPQTNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIH 363
DP++ TY + R GKGGFA+CYE D + YA EK+ EI +H
Sbjct: 55 DPRSGRTYLKGRLLGKGGFARCYEATDTETGSAYAVKVIPQSRVAKPHQREKILNEIELH 114
Query: 364 RSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQ 543
R LQH+H+V F FED+ NIYI LELC ++S+ + K R + EPE R+Y+ QIL G++
Sbjct: 115 RDLQHRHIVRFSHHFEDADNIYIFLELCSRKSLAHIWKARHTLLEPEVRYYLRQILSGLK 174
Query: 544 YLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTK 723
YLH + I+HRDLKLGN F+ +++ +K+GDFGLAAR+E +RK+T+CGTPNY+APE+L +
Sbjct: 175 YLHQRGILHRDLKLGNFFITENMELKVGDFGLAARLEPPEQRKKTICGTPNYVAPEVLLR 234
Query: 724 K 726
+
Sbjct: 235 Q 235
>AL592166-11|CAI13006.1| 646|Homo sapiens polo-like kinase 3
(Drosophila) protein.
Length = 646
Score = 203 bits (496), Expect = 4e-52
Identities = 88/181 (48%), Positives = 123/181 (67%)
Frame = +1
Query: 184 DPQTNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIH 363
DP++ TY + R GKGGFA+CYE D + YA EK+ EI +H
Sbjct: 55 DPRSGRTYLKGRLLGKGGFARCYEATDTETGSAYAVKVIPQSRVAKPHQREKILNEIELH 114
Query: 364 RSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQ 543
R LQH+H+V F FED+ NIYI LELC ++S+ + K R + EPE R+Y+ QIL G++
Sbjct: 115 RDLQHRHIVRFSHHFEDADNIYIFLELCSRKSLAHIWKARHTLLEPEVRYYLRQILSGLK 174
Query: 544 YLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTK 723
YLH + I+HRDLKLGN F+ +++ +K+GDFGLAAR+E +RK+T+CGTPNY+APE+L +
Sbjct: 175 YLHQRGILHRDLKLGNFFITENMELKVGDFGLAARLEPPEQRKKTICGTPNYVAPEVLLR 234
Query: 724 K 726
+
Sbjct: 235 Q 235
>AJ293866-1|CAC10659.1| 646|Homo sapiens FNK serine/threonine
protein kinase protein.
Length = 646
Score = 203 bits (496), Expect = 4e-52
Identities = 88/181 (48%), Positives = 123/181 (67%)
Frame = +1
Query: 184 DPQTNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIH 363
DP++ TY + R GKGGFA+CYE D + YA EK+ EI +H
Sbjct: 55 DPRSGRTYLKGRLLGKGGFARCYEATDTETGSAYAVKVIPQSRVVKPHQREKILNEIELH 114
Query: 364 RSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQ 543
R LQH+H+V F FED+ NIYI LELC ++S+ + K R + EPE R+Y+ QIL G++
Sbjct: 115 RDLQHRHIVRFSHHFEDADNIYIFLELCSRKSLAHIWKARHTLLEPEVRYYLRQILSGLK 174
Query: 544 YLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTK 723
YLH + I+HRDLKLGN F+ +++ +K+GDFGLAAR+E +RK+T+CGTPNY+APE+L +
Sbjct: 175 YLHQRGILHRDLKLGNFFITENMELKVGDFGLAARLEPPEQRKKTICGTPNYVAPEVLLR 234
Query: 724 K 726
+
Sbjct: 235 Q 235
>AB209875-1|BAD93112.1| 621|Homo sapiens polo-like kinase 3 variant
protein.
Length = 621
Score = 198 bits (482), Expect = 2e-50
Identities = 86/175 (49%), Positives = 119/175 (68%)
Frame = +1
Query: 202 TYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHK 381
TY + R GKGGFA+CYE D + YA EK+ EI +HR LQH+
Sbjct: 36 TYLKGRLLGKGGFARCYEATDTETGSAYAVKVIPQSRVAKPHQREKILNEIELHRDLQHR 95
Query: 382 HVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKR 561
H+V F FED+ NIYI LELC ++S+ + K R + EPE R+Y+ QIL G++YLH +
Sbjct: 96 HIVRFSHHFEDADNIYIFLELCSRKSLAHIWKARHTLLEPEVRYYLRQILSGLKYLHQRG 155
Query: 562 IIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
I+HRDLKLGN F+ +++ +K+GDFGLAAR+E +RK+T+CGTPNY+APE+L ++
Sbjct: 156 ILHRDLKLGNFFITENMELKVGDFGLAARLEPPEQRKKTICGTPNYVAPEVLLRQ 210
>U85755-1|AAD00575.1| 299|Homo sapiens serum-inducible kinase
protein.
Length = 299
Score = 175 bits (425), Expect = 2e-43
Identities = 73/131 (55%), Positives = 103/131 (78%)
Frame = +1
Query: 334 EKMAQEISIHRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRF 513
EK+ +EI +HR L HKHVV F+ +FED NIYI+LE C +RSM + K RK +TEPE R+
Sbjct: 16 EKIDKEIELHRILHHKHVVQFYHYFEDKENIYILLEYCSRRSMAHILKARKVLTEPEVRY 75
Query: 514 YMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTP 693
Y+ QI+ G++YLH + I+HRDLKLGN F+++ + +K+GDFGLAAR+E R++T+CGTP
Sbjct: 76 YLRQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGDFGLAARLEPLEHRRRTICGTP 135
Query: 694 NYIAPEILTKK 726
NY++PE+L K+
Sbjct: 136 NYLSPEVLNKQ 146
>AK131198-1|BAD18393.1| 706|Homo sapiens protein ( Homo sapiens
cDNA FLJ16039 fis, clone ADRGL2001554, weakly similar
to SERINE/THREONINE-PROTEIN KINASE PLK (EC 2.7.1.-). ).
Length = 706
Score = 174 bits (424), Expect = 2e-43
Identities = 81/164 (49%), Positives = 108/164 (65%)
Frame = +1
Query: 226 GKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKHVVGFHSF 405
GKGGFA YE+ I + + YAG EK EI IH+SL H H+ +
Sbjct: 46 GKGGFAIVYELTSIRTGKKYAGKVVEKAGLTKPKYLEKFMSEIRIHQSLDHPHICKMYKH 105
Query: 406 FEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKL 585
FED+ Y+ILELC ++ L + R+ +TEPE ++++ QI+ V YLH + IIHRDLKL
Sbjct: 106 FEDNRYHYLILELCSNETLAHLLRVRECLTEPEVQYFLLQIIDAVSYLHKRCIIHRDLKL 165
Query: 586 GNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEIL 717
GN+FLD++L VK+GD GLAA++ ERK+T+CGTPNYIAPEIL
Sbjct: 166 GNIFLDENLEVKVGDLGLAAQLNEPNERKKTMCGTPNYIAPEIL 209
>AB209179-1|BAD92416.1| 546|Homo sapiens polo-like kinase variant
protein.
Length = 546
Score = 160 bits (389), Expect = 4e-39
Identities = 68/91 (74%), Positives = 84/91 (92%)
Frame = +1
Query: 454 RSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDF 633
+S++ELHKRRKA+TEPE R+Y+ QI+LG QYLH R+IHRDLKLGNLFL++DL VKIGDF
Sbjct: 79 QSLLELHKRRKALTEPEARYYLRQIVLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDF 138
Query: 634 GLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
GLA ++EY+GERK+TLCGTPNYIAPE+L+KK
Sbjct: 139 GLATKVEYDGERKKTLCGTPNYIAPEVLSKK 169
>AB006972-1|BAB69958.1| 970|Homo sapiens Sak protein.
Length = 970
Score = 140 bits (338), Expect = 6e-33
Identities = 68/167 (40%), Positives = 98/167 (58%), Gaps = 1/167 (0%)
Frame = +1
Query: 226 GKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKHVVGFHSF 405
GKG FA Y + I S A +++ E+ IH L+H ++ +++
Sbjct: 19 GKGSFAGVYRAESIHSGLEVAIKMIDKKAMYKAGMVQRVQNEVKIHCQLKHPSILELYNY 78
Query: 406 FEDSLNIYIILELCKKRSMMELHKRR-KAITEPETRFYMHQILLGVQYLHSKRIIHRDLK 582
FEDS +Y++LE+C M K R K +E E R +MHQI+ G+ YLHS I+HRDL
Sbjct: 79 FEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLHSHGILHRDLT 138
Query: 583 LGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTK 723
L NL L ++++KI DFGLA +++ E+ TLCGTPNYI+PEI T+
Sbjct: 139 LSNLLLTRNMNIKIADFGLATQLKMPHEKHYTLCGTPNYISPEIATR 185
>Y13115-1|CAA73575.1| 970|Homo sapiens serine/threonine protein
kinase protein.
Length = 970
Score = 138 bits (335), Expect = 1e-32
Identities = 67/167 (40%), Positives = 98/167 (58%), Gaps = 1/167 (0%)
Frame = +1
Query: 226 GKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKHVVGFHSF 405
GKG FA Y + I + A +++ E+ IH L+H ++ +++
Sbjct: 19 GKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVKNEVKIHCQLKHPSILELYNY 78
Query: 406 FEDSLNIYIILELCKKRSMMELHKRR-KAITEPETRFYMHQILLGVQYLHSKRIIHRDLK 582
FEDS +Y++LE+C M K R K +E E R +MHQI+ G+ YLHS I+HRDL
Sbjct: 79 FEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLHSHGILHRDLT 138
Query: 583 LGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTK 723
L NL L ++++KI DFGLA +++ E+ TLCGTPNYI+PEI T+
Sbjct: 139 LSNLLLTRNMNIKIADFGLATQLKMPHEKHYTLCGTPNYISPEIATR 185
>BC036023-1|AAH36023.1| 970|Homo sapiens polo-like kinase 4
(Drosophila) protein.
Length = 970
Score = 138 bits (335), Expect = 1e-32
Identities = 67/167 (40%), Positives = 98/167 (58%), Gaps = 1/167 (0%)
Frame = +1
Query: 226 GKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKHVVGFHSF 405
GKG FA Y + I + A +++ E+ IH L+H ++ +++
Sbjct: 19 GKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVQNEVKIHCQLKHPSILELYNY 78
Query: 406 FEDSLNIYIILELCKKRSMMELHKRR-KAITEPETRFYMHQILLGVQYLHSKRIIHRDLK 582
FEDS +Y++LE+C M K R K +E E R +MHQI+ G+ YLHS I+HRDL
Sbjct: 79 FEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLHSHGILHRDLT 138
Query: 583 LGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTK 723
L NL L ++++KI DFGLA +++ E+ TLCGTPNYI+PEI T+
Sbjct: 139 LSNLLLTRNMNIKIADFGLATQLKMPHEKHYTLCGTPNYISPEIATR 185
>BC017306-1|AAH17306.1| 628|Homo sapiens NUAK family, SNF1-like
kinase, 2 protein.
Length = 628
Score = 116 bits (279), Expect = 9e-26
Identities = 59/182 (32%), Positives = 96/182 (52%)
Frame = +1
Query: 181 HDPQTNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISI 360
H Y+ L GKG + K + ++ +S ++ A + +EI I
Sbjct: 45 HKHNLRHRYEFLETLGKGTYGKVKKARE-SSGRLVAIKSIRKDKIKDEQDLMHIRREIEI 103
Query: 361 HRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGV 540
SL H H++ H FE+S I I++E + + + R+ ++E E R + QI+ V
Sbjct: 104 MSSLNHPHIIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAV 163
Query: 541 QYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILT 720
Y H R++HRDLKL N+ LD + ++KI DFGL + + ++G+ QT CG+P Y +PEI+
Sbjct: 164 HYCHQNRVVHRDLKLENILLDANGNIKIADFGL-SNLYHQGKFLQTFCGSPLYASPEIVN 222
Query: 721 KK 726
K
Sbjct: 223 GK 224
>AK074830-1|BAC11234.1| 628|Homo sapiens protein ( Homo sapiens
cDNA FLJ90349 fis, clone NT2RP2003179, weakly similar to
PUTATIVE SERINE/THREONINE-PROTEIN KINASE EMK (EC
2.7.1.-). ).
Length = 628
Score = 116 bits (279), Expect = 9e-26
Identities = 59/182 (32%), Positives = 96/182 (52%)
Frame = +1
Query: 181 HDPQTNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISI 360
H Y+ L GKG + K + ++ +S ++ A + +EI I
Sbjct: 45 HKHNLRHRYEFLETLGKGTYGKVKKARE-SSGRLVAIKSIRKDKIKDEQDLMHIRREIEI 103
Query: 361 HRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGV 540
SL H H++ H FE+S I I++E + + + R+ ++E E R + QI+ V
Sbjct: 104 MSSLNHPHIIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAV 163
Query: 541 QYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILT 720
Y H R++HRDLKL N+ LD + ++KI DFGL + + ++G+ QT CG+P Y +PEI+
Sbjct: 164 HYCHQNRVVHRDLKLENILLDANGNIKIADFGL-SNLYHQGKFLQTFCGSPLYASPEIVN 222
Query: 721 KK 726
K
Sbjct: 223 GK 224
>AB011109-1|BAA25463.2| 698|Homo sapiens KIAA0537 protein protein.
Length = 698
Score = 110 bits (265), Expect = 4e-24
Identities = 57/179 (31%), Positives = 89/179 (49%)
Frame = +1
Query: 181 HDPQTNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISI 360
H Y+ GKG + K + S ++ A + +EI I
Sbjct: 84 HKHNLKHRYELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDEQDMVHIRREIEI 143
Query: 361 HRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGV 540
SL H H++ + FE+ I II+E K + + R+ ++E ETR + QI+ V
Sbjct: 144 MSSLNHPHIISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAV 203
Query: 541 QYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEIL 717
Y H ++HRDLKL N+ LDD+ ++KI DFGL + + + + QT CG+P Y +PEI+
Sbjct: 204 HYCHKNGVVHRDLKLENILLDDNCNIKIADFGL-SNLYQKDKFLQTFCGSPLYASPEIV 261
>L33881-1|AAB17011.1| 587|Homo sapiens protein kinase C iota
protein.
Length = 587
Score = 109 bits (263), Expect = 7e-24
Identities = 56/172 (32%), Positives = 91/172 (52%), Gaps = 1/172 (0%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISI-HRSLQHK 381
+ LR G+G +AK ++ +++IYA + + E + ++ H
Sbjct: 245 FDLLRVIGRGSYAKVLLVRLKKTDRIYAMKVVKKELVNDDEDIDWVQTEKHVFEQASNHP 304
Query: 382 HVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKR 561
+VG HS F+ ++ ++E +M +R++ + E RFY +I L + YLH +
Sbjct: 305 FLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQRKLPEEHARFYSAEISLALNYLHERG 364
Query: 562 IIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEIL 717
II+RDLKL N+ LD + H+K+ D+G+ G+ T CGTPNYIAPEIL
Sbjct: 365 IIYRDLKLDNVLLDSEGHIKLTDYGMCKEGLRPGDTTSTFCGTPNYIAPEIL 416
>L18964-1|AAA60171.1| 587|Homo sapiens protein kinase C iota
protein.
Length = 587
Score = 109 bits (263), Expect = 7e-24
Identities = 56/172 (32%), Positives = 91/172 (52%), Gaps = 1/172 (0%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISI-HRSLQHK 381
+ LR G+G +AK ++ +++IYA + + E + ++ H
Sbjct: 245 FDLLRVIGRGSYAKVLLVRLKKTDRIYAMKVVKKELVNDDEDIDWVQTEKHVFEQASNHP 304
Query: 382 HVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKR 561
+VG HS F+ ++ ++E +M +R++ + E RFY +I L + YLH +
Sbjct: 305 FLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQRKLPEEHARFYSAEISLALNYLHERG 364
Query: 562 IIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEIL 717
II+RDLKL N+ LD + H+K+ D+G+ G+ T CGTPNYIAPEIL
Sbjct: 365 IIYRDLKLDNVLLDSEGHIKLTDYGMCKEGLRPGDTTSTFCGTPNYIAPEIL 416
>BC022016-1|AAH22016.3| 587|Homo sapiens protein kinase C, iota
protein.
Length = 587
Score = 109 bits (263), Expect = 7e-24
Identities = 56/172 (32%), Positives = 91/172 (52%), Gaps = 1/172 (0%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISI-HRSLQHK 381
+ LR G+G +AK ++ +++IYA + + E + ++ H
Sbjct: 245 FDLLRVIGRGSYAKVLLVRLKKTDRIYAMKVVKKELVNDDEDIDWVQTEKHVFEQASNHP 304
Query: 382 HVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKR 561
+VG HS F+ ++ ++E +M +R++ + E RFY +I L + YLH +
Sbjct: 305 FLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQRKLPEEHARFYSAEISLALNYLHERG 364
Query: 562 IIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEIL 717
II+RDLKL N+ LD + H+K+ D+G+ G+ T CGTPNYIAPEIL
Sbjct: 365 IIYRDLKLDNVLLDSEGHIKLTDYGMCKEGLRPGDTTSTFCGTPNYIAPEIL 416
>U78073-1|AAB36946.1| 136|Homo sapiens polo like kinase protein.
Length = 136
Score = 108 bits (259), Expect = 2e-23
Identities = 46/91 (50%), Positives = 63/91 (69%)
Frame = +1
Query: 184 DPQTNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIH 363
DP++ Y R RF GKGGFAKC+EI D+ + +++AG EKM+ EISIH
Sbjct: 46 DPRSRRRYVRGRFLGKGGFAKCFEISDVDTKEVFAGKIVPKSLLLKPHQREKMSMEISIH 105
Query: 364 RSLQHKHVVGFHSFFEDSLNIYIILELCKKR 456
RSL H+HVVGFH FFED+ ++++LELC++R
Sbjct: 106 RSLAHQHVVGFHGFFEDNDFVFVVLELCRRR 136
>Z15108-1|CAA78813.1| 584|Homo sapiens protein kinase C zeta
protein.
Length = 584
Score = 107 bits (257), Expect = 4e-23
Identities = 54/172 (31%), Positives = 93/172 (54%), Gaps = 1/172 (0%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISI-HRSLQHK 381
+ +R G+G +AK ++ ++QIYA + + E + ++ +
Sbjct: 244 FDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQASSNP 303
Query: 382 HVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKR 561
+VG HS F+ + +++++E +M +R++ + E RFY +I + + +LH +
Sbjct: 304 FLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLHERG 363
Query: 562 IIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEIL 717
II+RDLKL N+ LD D H+K+ D+G+ G+ T CGTPNYIAPEIL
Sbjct: 364 IIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEIL 415
>BT007082-1|AAP35745.1| 592|Homo sapiens protein kinase C, zeta
protein.
Length = 592
Score = 107 bits (257), Expect = 4e-23
Identities = 54/172 (31%), Positives = 93/172 (54%), Gaps = 1/172 (0%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISI-HRSLQHK 381
+ +R G+G +AK ++ ++QIYA + + E + ++ +
Sbjct: 252 FDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQASSNP 311
Query: 382 HVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKR 561
+VG HS F+ + +++++E +M +R++ + E RFY +I + + +LH +
Sbjct: 312 FLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLHERG 371
Query: 562 IIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEIL 717
II+RDLKL N+ LD D H+K+ D+G+ G+ T CGTPNYIAPEIL
Sbjct: 372 IIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEIL 423
>BC014270-1|AAH14270.1| 592|Homo sapiens protein kinase C, zeta
protein.
Length = 592
Score = 107 bits (257), Expect = 4e-23
Identities = 54/172 (31%), Positives = 93/172 (54%), Gaps = 1/172 (0%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISI-HRSLQHK 381
+ +R G+G +AK ++ ++QIYA + + E + ++ +
Sbjct: 252 FDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQASSNP 311
Query: 382 HVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKR 561
+VG HS F+ + +++++E +M +R++ + E RFY +I + + +LH +
Sbjct: 312 FLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLHERG 371
Query: 562 IIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEIL 717
II+RDLKL N+ LD D H+K+ D+G+ G+ T CGTPNYIAPEIL
Sbjct: 372 IIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEIL 423
>BC008058-1|AAH08058.1| 592|Homo sapiens protein kinase C, zeta
protein.
Length = 592
Score = 107 bits (257), Expect = 4e-23
Identities = 54/172 (31%), Positives = 93/172 (54%), Gaps = 1/172 (0%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISI-HRSLQHK 381
+ +R G+G +AK ++ ++QIYA + + E + ++ +
Sbjct: 252 FDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQASSNP 311
Query: 382 HVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKR 561
+VG HS F+ + +++++E +M +R++ + E RFY +I + + +LH +
Sbjct: 312 FLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLHERG 371
Query: 562 IIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEIL 717
II+RDLKL N+ LD D H+K+ D+G+ G+ T CGTPNYIAPEIL
Sbjct: 372 IIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEIL 423
>AL645703-1|CAI21535.1| 592|Homo sapiens protein kinase C, zeta
protein.
Length = 592
Score = 107 bits (257), Expect = 4e-23
Identities = 54/172 (31%), Positives = 93/172 (54%), Gaps = 1/172 (0%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISI-HRSLQHK 381
+ +R G+G +AK ++ ++QIYA + + E + ++ +
Sbjct: 252 FDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQASSNP 311
Query: 382 HVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKR 561
+VG HS F+ + +++++E +M +R++ + E RFY +I + + +LH +
Sbjct: 312 FLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLHERG 371
Query: 562 IIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEIL 717
II+RDLKL N+ LD D H+K+ D+G+ G+ T CGTPNYIAPEIL
Sbjct: 372 IIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEIL 423
>AL590822-9|CAI12484.1| 592|Homo sapiens protein kinase C, zeta
protein.
Length = 592
Score = 107 bits (257), Expect = 4e-23
Identities = 54/172 (31%), Positives = 93/172 (54%), Gaps = 1/172 (0%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISI-HRSLQHK 381
+ +R G+G +AK ++ ++QIYA + + E + ++ +
Sbjct: 252 FDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQASSNP 311
Query: 382 HVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKR 561
+VG HS F+ + +++++E +M +R++ + E RFY +I + + +LH +
Sbjct: 312 FLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLHERG 371
Query: 562 IIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEIL 717
II+RDLKL N+ LD D H+K+ D+G+ G+ T CGTPNYIAPEIL
Sbjct: 372 IIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEIL 423
>AL391845-5|CAI15438.1| 592|Homo sapiens protein kinase C, zeta
protein.
Length = 592
Score = 107 bits (257), Expect = 4e-23
Identities = 54/172 (31%), Positives = 93/172 (54%), Gaps = 1/172 (0%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISI-HRSLQHK 381
+ +R G+G +AK ++ ++QIYA + + E + ++ +
Sbjct: 252 FDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQASSNP 311
Query: 382 HVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKR 561
+VG HS F+ + +++++E +M +R++ + E RFY +I + + +LH +
Sbjct: 312 FLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLHERG 371
Query: 562 IIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEIL 717
II+RDLKL N+ LD D H+K+ D+G+ G+ T CGTPNYIAPEIL
Sbjct: 372 IIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEIL 423
>X90725-1|CAA62260.1| 136|Homo sapiens polo-like kinase protein.
Length = 136
Score = 106 bits (255), Expect = 7e-23
Identities = 46/91 (50%), Positives = 62/91 (68%)
Frame = +1
Query: 184 DPQTNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIH 363
DP++ Y R RF GKGGFAKC+EI D + +++AG EKM+ EISIH
Sbjct: 46 DPRSRRRYVRGRFLGKGGFAKCFEISDADTKEVFAGKIVPKSLLLKPHQREKMSMEISIH 105
Query: 364 RSLQHKHVVGFHSFFEDSLNIYIILELCKKR 456
RSL H+HVVGFH FFED+ ++++LELC++R
Sbjct: 106 RSLAHQHVVGFHGFFEDTDFVFVVLELCRRR 136
>L14283-1|AAA36488.1| 592|Homo sapiens protein kinase C zeta
protein.
Length = 592
Score = 106 bits (255), Expect = 7e-23
Identities = 54/172 (31%), Positives = 93/172 (54%), Gaps = 1/172 (0%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISI-HRSLQHK 381
+ +R G+G +AK ++ ++QIYA + + E + ++ +
Sbjct: 252 FDLIRVIGRGTYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQASSNP 311
Query: 382 HVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKR 561
+VG HS F+ + +++++E +M +R++ + E RFY +I + + +LH +
Sbjct: 312 FLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLHERG 371
Query: 562 IIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEIL 717
II+RDLKL N+ LD D H+K+ D+G+ G+ T CGTPNYIAPEIL
Sbjct: 372 IIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEIL 423
>BC020479-1|AAH20479.1| 466|Homo sapiens AKT3 protein protein.
Length = 466
Score = 104 bits (249), Expect = 4e-22
Identities = 55/179 (30%), Positives = 86/179 (48%)
Frame = +1
Query: 181 HDPQTNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISI 360
H +T + + L+ GKG F K +++ AS + YA E +
Sbjct: 140 HKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRV 199
Query: 361 HRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGV 540
++ +H + F+ + ++E + R + +E TRFY +I+ +
Sbjct: 200 LKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSAL 259
Query: 541 QYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEIL 717
YLHS +I++RDLKL NL LD D H+KI DFGL + +T CGTP Y+APE+L
Sbjct: 260 DYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVL 318
>AY005799-1|AAF91073.1| 465|Homo sapiens protein kinase B gamma 1
protein.
Length = 465
Score = 104 bits (249), Expect = 4e-22
Identities = 55/179 (30%), Positives = 86/179 (48%)
Frame = +1
Query: 181 HDPQTNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISI 360
H +T + + L+ GKG F K +++ AS + YA E +
Sbjct: 140 HKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRV 199
Query: 361 HRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGV 540
++ +H + F+ + ++E + R + +E TRFY +I+ +
Sbjct: 200 LKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSAL 259
Query: 541 QYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEIL 717
YLHS +I++RDLKL NL LD D H+KI DFGL + +T CGTP Y+APE+L
Sbjct: 260 DYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVL 318
>AL662889-3|CAH73073.1| 479|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 479
Score = 104 bits (249), Expect = 4e-22
Identities = 55/179 (30%), Positives = 86/179 (48%)
Frame = +1
Query: 181 HDPQTNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISI 360
H +T + + L+ GKG F K +++ AS + YA E +
Sbjct: 140 HKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRV 199
Query: 361 HRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGV 540
++ +H + F+ + ++E + R + +E TRFY +I+ +
Sbjct: 200 LKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSAL 259
Query: 541 QYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEIL 717
YLHS +I++RDLKL NL LD D H+KI DFGL + +T CGTP Y+APE+L
Sbjct: 260 DYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVL 318
>AL662889-2|CAH73072.1| 465|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 465
Score = 104 bits (249), Expect = 4e-22
Identities = 55/179 (30%), Positives = 86/179 (48%)
Frame = +1
Query: 181 HDPQTNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISI 360
H +T + + L+ GKG F K +++ AS + YA E +
Sbjct: 140 HKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRV 199
Query: 361 HRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGV 540
++ +H + F+ + ++E + R + +E TRFY +I+ +
Sbjct: 200 LKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSAL 259
Query: 541 QYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEIL 717
YLHS +I++RDLKL NL LD D H+KI DFGL + +T CGTP Y+APE+L
Sbjct: 260 DYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVL 318
>AL592151-2|CAH72892.1| 479|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 479
Score = 104 bits (249), Expect = 4e-22
Identities = 55/179 (30%), Positives = 86/179 (48%)
Frame = +1
Query: 181 HDPQTNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISI 360
H +T + + L+ GKG F K +++ AS + YA E +
Sbjct: 140 HKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRV 199
Query: 361 HRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGV 540
++ +H + F+ + ++E + R + +E TRFY +I+ +
Sbjct: 200 LKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSAL 259
Query: 541 QYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEIL 717
YLHS +I++RDLKL NL LD D H+KI DFGL + +T CGTP Y+APE+L
Sbjct: 260 DYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVL 318
>AL592151-1|CAH72891.1| 465|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 465
Score = 104 bits (249), Expect = 4e-22
Identities = 55/179 (30%), Positives = 86/179 (48%)
Frame = +1
Query: 181 HDPQTNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISI 360
H +T + + L+ GKG F K +++ AS + YA E +
Sbjct: 140 HKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRV 199
Query: 361 HRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGV 540
++ +H + F+ + ++E + R + +E TRFY +I+ +
Sbjct: 200 LKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSAL 259
Query: 541 QYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEIL 717
YLHS +I++RDLKL NL LD D H+KI DFGL + +T CGTP Y+APE+L
Sbjct: 260 DYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVL 318
>AL591721-2|CAH71867.1| 479|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 479
Score = 104 bits (249), Expect = 4e-22
Identities = 55/179 (30%), Positives = 86/179 (48%)
Frame = +1
Query: 181 HDPQTNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISI 360
H +T + + L+ GKG F K +++ AS + YA E +
Sbjct: 140 HKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRV 199
Query: 361 HRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGV 540
++ +H + F+ + ++E + R + +E TRFY +I+ +
Sbjct: 200 LKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSAL 259
Query: 541 QYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEIL 717
YLHS +I++RDLKL NL LD D H+KI DFGL + +T CGTP Y+APE+L
Sbjct: 260 DYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVL 318
>AL591721-1|CAH71866.1| 465|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 465
Score = 104 bits (249), Expect = 4e-22
Identities = 55/179 (30%), Positives = 86/179 (48%)
Frame = +1
Query: 181 HDPQTNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISI 360
H +T + + L+ GKG F K +++ AS + YA E +
Sbjct: 140 HKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRV 199
Query: 361 HRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGV 540
++ +H + F+ + ++E + R + +E TRFY +I+ +
Sbjct: 200 LKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSAL 259
Query: 541 QYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEIL 717
YLHS +I++RDLKL NL LD D H+KI DFGL + +T CGTP Y+APE+L
Sbjct: 260 DYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVL 318
>AJ245709-1|CAB53537.1| 479|Homo sapiens Akt-3 protein protein.
Length = 479
Score = 104 bits (249), Expect = 4e-22
Identities = 55/179 (30%), Positives = 86/179 (48%)
Frame = +1
Query: 181 HDPQTNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISI 360
H +T + + L+ GKG F K +++ AS + YA E +
Sbjct: 140 HKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRV 199
Query: 361 HRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGV 540
++ +H + F+ + ++E + R + +E TRFY +I+ +
Sbjct: 200 LKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSAL 259
Query: 541 QYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEIL 717
YLHS +I++RDLKL NL LD D H+KI DFGL + +T CGTP Y+APE+L
Sbjct: 260 DYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVL 318
>AF135794-1|AAD24196.1| 479|Homo sapiens AKT3 protein kinase
protein.
Length = 479
Score = 104 bits (249), Expect = 4e-22
Identities = 55/179 (30%), Positives = 86/179 (48%)
Frame = +1
Query: 181 HDPQTNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISI 360
H +T + + L+ GKG F K +++ AS + YA E +
Sbjct: 140 HKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRV 199
Query: 361 HRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGV 540
++ +H + F+ + ++E + R + +E TRFY +I+ +
Sbjct: 200 LKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSAL 259
Query: 541 QYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEIL 717
YLHS +I++RDLKL NL LD D H+KI DFGL + +T CGTP Y+APE+L
Sbjct: 260 DYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVL 318
>AF124141-1|AAD29089.1| 479|Homo sapiens protein kinase B gamma
protein.
Length = 479
Score = 104 bits (249), Expect = 4e-22
Identities = 55/179 (30%), Positives = 86/179 (48%)
Frame = +1
Query: 181 HDPQTNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISI 360
H +T + + L+ GKG F K +++ AS + YA E +
Sbjct: 140 HKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRV 199
Query: 361 HRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGV 540
++ +H + F+ + ++E + R + +E TRFY +I+ +
Sbjct: 200 LKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSAL 259
Query: 541 QYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEIL 717
YLHS +I++RDLKL NL LD D H+KI DFGL + +T CGTP Y+APE+L
Sbjct: 260 DYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVL 318
>AF085234-1|AAL40392.1| 479|Homo sapiens STK-2 protein.
Length = 479
Score = 104 bits (249), Expect = 4e-22
Identities = 55/179 (30%), Positives = 86/179 (48%)
Frame = +1
Query: 181 HDPQTNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISI 360
H +T + + L+ GKG F K +++ AS + YA E +
Sbjct: 140 HKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRV 199
Query: 361 HRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGV 540
++ +H + F+ + ++E + R + +E TRFY +I+ +
Sbjct: 200 LKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSAL 259
Query: 541 QYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEIL 717
YLHS +I++RDLKL NL LD D H+KI DFGL + +T CGTP Y+APE+L
Sbjct: 260 DYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVL 318
>M34181-1|AAA60170.1| 351|Homo sapiens cAMP-dependent protein
kinase catalytic subunit protein.
Length = 351
Score = 103 bits (248), Expect = 5e-22
Identities = 57/174 (32%), Positives = 89/174 (51%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKH 384
++R + G G F + ++ A+ Q YA E E I +++
Sbjct: 44 FERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPF 103
Query: 385 VVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRI 564
+V F+D+ N+Y+++E M +R +EP RFY QI+L +YLHS +
Sbjct: 104 LVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 163
Query: 565 IHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
I+RDLK NL +D ++++ DFG A R++ R TLCGTP Y+APEI+ K
Sbjct: 164 IYRDLKPENLLIDHQGYIQVTDFGFAKRVK---GRTWTLCGTPEYLAPEIILSK 214
>DQ667174-1|ABG25919.1| 398|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 398
Score = 103 bits (248), Expect = 5e-22
Identities = 57/174 (32%), Positives = 89/174 (51%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKH 384
++R + G G F + ++ A+ Q YA E E I +++
Sbjct: 91 FERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPF 150
Query: 385 VVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRI 564
+V F+D+ N+Y+++E M +R +EP RFY QI+L +YLHS +
Sbjct: 151 LVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 210
Query: 565 IHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
I+RDLK NL +D ++++ DFG A R++ R TLCGTP Y+APEI+ K
Sbjct: 211 IYRDLKPENLLIDHQGYIQVTDFGFAKRVK---GRTWTLCGTPEYLAPEIILSK 261
>BC016285-1|AAH16285.1| 257|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 257
Score = 103 bits (248), Expect = 5e-22
Identities = 57/174 (32%), Positives = 89/174 (51%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKH 384
++R + G G F + ++ A+ Q YA E E I +++
Sbjct: 44 FERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPF 103
Query: 385 VVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRI 564
+V F+D+ N+Y+++E M +R +EP RFY QI+L +YLHS +
Sbjct: 104 LVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 163
Query: 565 IHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
I+RDLK NL +D ++++ DFG A R++ R TLCGTP Y+APEI+ K
Sbjct: 164 IYRDLKPENLLIDHQGYIQVTDFGFAKRVK---GRTWTLCGTPEYLAPEIILSK 214
>AL450063-11|CAI16854.1| 264|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 264
Score = 103 bits (248), Expect = 5e-22
Identities = 57/174 (32%), Positives = 89/174 (51%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKH 384
++R + G G F + ++ A+ Q YA E E I +++
Sbjct: 50 FERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPF 109
Query: 385 VVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRI 564
+V F+D+ N+Y+++E M +R +EP RFY QI+L +YLHS +
Sbjct: 110 LVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 169
Query: 565 IHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
I+RDLK NL +D ++++ DFG A R++ R TLCGTP Y+APEI+ K
Sbjct: 170 IYRDLKPENLLIDHQGYIQVTDFGFAKRVK---GRTWTLCGTPEYLAPEIILSK 220
>AL450063-10|CAI16853.1| 209|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 209
Score = 103 bits (248), Expect = 5e-22
Identities = 57/174 (32%), Positives = 89/174 (51%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKH 384
++R + G G F + ++ A+ Q YA E E I +++
Sbjct: 39 FERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPF 98
Query: 385 VVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRI 564
+V F+D+ N+Y+++E M +R +EP RFY QI+L +YLHS +
Sbjct: 99 LVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 158
Query: 565 IHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
I+RDLK NL +D ++++ DFG A R++ R TLCGTP Y+APEI+ K
Sbjct: 159 IYRDLKPENLLIDHQGYIQVTDFGFAKRVK---GRTWTLCGTPEYLAPEIILSK 209
>AL450063-7|CAI16850.1| 245|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 245
Score = 103 bits (248), Expect = 5e-22
Identities = 57/174 (32%), Positives = 89/174 (51%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKH 384
++R + G G F + ++ A+ Q YA E E I +++
Sbjct: 32 FERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPF 91
Query: 385 VVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRI 564
+V F+D+ N+Y+++E M +R +EP RFY QI+L +YLHS +
Sbjct: 92 LVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 151
Query: 565 IHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
I+RDLK NL +D ++++ DFG A R++ R TLCGTP Y+APEI+ K
Sbjct: 152 IYRDLKPENLLIDHQGYIQVTDFGFAKRVK---GRTWTLCGTPEYLAPEIILSK 202
>AL450063-6|CAI16849.1| 214|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 214
Score = 103 bits (248), Expect = 5e-22
Identities = 57/174 (32%), Positives = 89/174 (51%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKH 384
++R + G G F + ++ A+ Q YA E E I +++
Sbjct: 40 FERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPF 99
Query: 385 VVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRI 564
+V F+D+ N+Y+++E M +R +EP RFY QI+L +YLHS +
Sbjct: 100 LVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 159
Query: 565 IHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
I+RDLK NL +D ++++ DFG A R++ R TLCGTP Y+APEI+ K
Sbjct: 160 IYRDLKPENLLIDHQGYIQVTDFGFAKRVK---GRTWTLCGTPEYLAPEIILSK 210
>AL450063-3|CAI16846.1| 398|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 398
Score = 103 bits (248), Expect = 5e-22
Identities = 57/174 (32%), Positives = 89/174 (51%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKH 384
++R + G G F + ++ A+ Q YA E E I +++
Sbjct: 91 FERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPF 150
Query: 385 VVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRI 564
+V F+D+ N+Y+++E M +R +EP RFY QI+L +YLHS +
Sbjct: 151 LVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 210
Query: 565 IHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
I+RDLK NL +D ++++ DFG A R++ R TLCGTP Y+APEI+ K
Sbjct: 211 IYRDLKPENLLIDHQGYIQVTDFGFAKRVK---GRTWTLCGTPEYLAPEIILSK 261
>AL450063-2|CAI16845.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 351
Score = 103 bits (248), Expect = 5e-22
Identities = 57/174 (32%), Positives = 89/174 (51%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKH 384
++R + G G F + ++ A+ Q YA E E I +++
Sbjct: 44 FERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPF 103
Query: 385 VVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRI 564
+V F+D+ N+Y+++E M +R +EP RFY QI+L +YLHS +
Sbjct: 104 LVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 163
Query: 565 IHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
I+RDLK NL +D ++++ DFG A R++ R TLCGTP Y+APEI+ K
Sbjct: 164 IYRDLKPENLLIDHQGYIQVTDFGFAKRVK---GRTWTLCGTPEYLAPEIILSK 214
>AL450063-1|CAI16844.1| 257|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 257
Score = 103 bits (248), Expect = 5e-22
Identities = 57/174 (32%), Positives = 89/174 (51%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKH 384
++R + G G F + ++ A+ Q YA E E I +++
Sbjct: 44 FERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPF 103
Query: 385 VVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRI 564
+V F+D+ N+Y+++E M +R +EP RFY QI+L +YLHS +
Sbjct: 104 LVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 163
Query: 565 IHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
I+RDLK NL +D ++++ DFG A R++ R TLCGTP Y+APEI+ K
Sbjct: 164 IYRDLKPENLLIDHQGYIQVTDFGFAKRVK---GRTWTLCGTPEYLAPEIILSK 214
>AL359504-2|CAI14541.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 351
Score = 103 bits (248), Expect = 5e-22
Identities = 57/174 (32%), Positives = 89/174 (51%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKH 384
++R + G G F + ++ A+ Q YA E E I +++
Sbjct: 44 FERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPF 103
Query: 385 VVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRI 564
+V F+D+ N+Y+++E M +R +EP RFY QI+L +YLHS +
Sbjct: 104 LVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 163
Query: 565 IHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
I+RDLK NL +D ++++ DFG A R++ R TLCGTP Y+APEI+ K
Sbjct: 164 IYRDLKPENLLIDHQGYIQVTDFGFAKRVK---GRTWTLCGTPEYLAPEIILSK 214
>AL359504-1|CAI14540.1| 257|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 257
Score = 103 bits (248), Expect = 5e-22
Identities = 57/174 (32%), Positives = 89/174 (51%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKH 384
++R + G G F + ++ A+ Q YA E E I +++
Sbjct: 44 FERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPF 103
Query: 385 VVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRI 564
+V F+D+ N+Y+++E M +R +EP RFY QI+L +YLHS +
Sbjct: 104 LVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 163
Query: 565 IHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
I+RDLK NL +D ++++ DFG A R++ R TLCGTP Y+APEI+ K
Sbjct: 164 IYRDLKPENLLIDHQGYIQVTDFGFAKRVK---GRTWTLCGTPEYLAPEIILSK 214
>AB209189-1|BAD92426.1| 365|Homo sapiens cAMP-dependent protein
kinase catalytic subunit beta isoform 2 variant protein.
Length = 365
Score = 103 bits (248), Expect = 5e-22
Identities = 57/174 (32%), Positives = 89/174 (51%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKH 384
++R + G G F + ++ A+ Q YA E E I +++
Sbjct: 70 FERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPF 129
Query: 385 VVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRI 564
+V F+D+ N+Y+++E M +R +EP RFY QI+L +YLHS +
Sbjct: 130 LVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 189
Query: 565 IHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
I+RDLK NL +D ++++ DFG A R++ R TLCGTP Y+APEI+ K
Sbjct: 190 IYRDLKPENLLIDHQGYIQVTDFGFAKRVK---GRTWTLCGTPEYLAPEIILSK 240
>M34182-1|AAC41690.1| 360|Homo sapiens protein kinase A
gamma-subunit protein.
Length = 360
Score = 103 bits (246), Expect = 9e-22
Identities = 57/178 (32%), Positives = 90/178 (50%)
Frame = +1
Query: 193 TNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSL 372
++ ++RLR G G F + ++ + YA E + E I +++
Sbjct: 49 SSDQFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAI 108
Query: 373 QHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLH 552
+V F+D+ +Y+++E M +R +EP FY Q++L VQYLH
Sbjct: 109 DFPFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLH 168
Query: 553 SKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
S +IHRDLK NL +D ++++ DFG A R++ R TLCGTP Y+APEI+ K
Sbjct: 169 SLDLIHRDLKPENLLIDQQGYLQVTDFGFAKRVK---GRTWTLCGTPEYLAPEIILSK 223
>DQ667175-1|ABG25920.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, gamma protein.
Length = 351
Score = 103 bits (246), Expect = 9e-22
Identities = 57/178 (32%), Positives = 90/178 (50%)
Frame = +1
Query: 193 TNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSL 372
++ ++RLR G G F + ++ + YA E + E I +++
Sbjct: 40 SSDQFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAI 99
Query: 373 QHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLH 552
+V F+D+ +Y+++E M +R +EP FY Q++L VQYLH
Sbjct: 100 DFPFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLH 159
Query: 553 SKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
S +IHRDLK NL +D ++++ DFG A R++ R TLCGTP Y+APEI+ K
Sbjct: 160 SLDLIHRDLKPENLLIDQQGYLQVTDFGFAKRVK---GRTWTLCGTPEYLAPEIILSK 214
>BC043487-1|AAH43487.1| 505|Homo sapiens
calcium/calmodulin-dependent protein kinase kinase 1,
alpha protein.
Length = 505
Score = 103 bits (246), Expect = 9e-22
Identities = 49/131 (37%), Positives = 82/131 (62%), Gaps = 2/131 (1%)
Frame = +1
Query: 334 EKMAQEISIHRSLQHKHVVGFHSFFEDSL--NIYIILELCKKRSMMELHKRRKAITEPET 507
E++ QEI+I + L H +VV +D N+Y++ +L +K +ME+ K +E +
Sbjct: 194 ERVYQEIAILKKLDHVNVVKLIEVLDDPAEDNLYLVFDLLRKGPVMEV-PCDKPFSEEQA 252
Query: 508 RFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCG 687
R Y+ ++LG++YLH ++I+HRD+K NL L DD HVKI DFG++ + E + + G
Sbjct: 253 RLYLRDVILGLEYLHCQKIVHRDIKPSNLLLGDDGHVKIADFGVSNQFEGNDAQLSSTAG 312
Query: 688 TPNYIAPEILT 720
TP ++APE ++
Sbjct: 313 TPAFMAPEAIS 323
>BC039888-1|AAH39888.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, gamma protein.
Length = 351
Score = 103 bits (246), Expect = 9e-22
Identities = 57/178 (32%), Positives = 90/178 (50%)
Frame = +1
Query: 193 TNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSL 372
++ ++RLR G G F + ++ + YA E + E I +++
Sbjct: 40 SSDQFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAI 99
Query: 373 QHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLH 552
+V F+D+ +Y+++E M +R +EP FY Q++L VQYLH
Sbjct: 100 DFPFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLH 159
Query: 553 SKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
S +IHRDLK NL +D ++++ DFG A R++ R TLCGTP Y+APEI+ K
Sbjct: 160 SLDLIHRDLKPENLLIDQQGYLQVTDFGFAKRVK---GRTWTLCGTPEYLAPEIILSK 214
>AL162730-1|CAH71828.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, gamma protein.
Length = 351
Score = 103 bits (246), Expect = 9e-22
Identities = 57/178 (32%), Positives = 90/178 (50%)
Frame = +1
Query: 193 TNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSL 372
++ ++RLR G G F + ++ + YA E + E I +++
Sbjct: 40 SSDQFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAI 99
Query: 373 QHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLH 552
+V F+D+ +Y+++E M +R +EP FY Q++L VQYLH
Sbjct: 100 DFPFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLH 159
Query: 553 SKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
S +IHRDLK NL +D ++++ DFG A R++ R TLCGTP Y+APEI+ K
Sbjct: 160 SLDLIHRDLKPENLLIDQQGYLQVTDFGFAKRVK---GRTWTLCGTPEYLAPEIILSK 214
>AJ001597-1|CAA04863.1| 351|Homo sapiens cAMP-dependent protein
kinase gamma isoform protein.
Length = 351
Score = 103 bits (246), Expect = 9e-22
Identities = 57/178 (32%), Positives = 90/178 (50%)
Frame = +1
Query: 193 TNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSL 372
++ ++RLR G G F + ++ + YA E + E I +++
Sbjct: 40 SSDQFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAI 99
Query: 373 QHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLH 552
+V F+D+ +Y+++E M +R +EP FY Q++L VQYLH
Sbjct: 100 DFPFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLH 159
Query: 553 SKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
S +IHRDLK NL +D ++++ DFG A R++ R TLCGTP Y+APEI+ K
Sbjct: 160 SLDLIHRDLKPENLLIDQQGYLQVTDFGFAKRVK---GRTWTLCGTPEYLAPEIILSK 214
>AF425301-1|AAN37387.1| 505|Homo sapiens CAMKK alpha protein
protein.
Length = 505
Score = 103 bits (246), Expect = 9e-22
Identities = 49/131 (37%), Positives = 82/131 (62%), Gaps = 2/131 (1%)
Frame = +1
Query: 334 EKMAQEISIHRSLQHKHVVGFHSFFEDSL--NIYIILELCKKRSMMELHKRRKAITEPET 507
E++ QEI+I + L H +VV +D N+Y++ +L +K +ME+ K +E +
Sbjct: 194 ERVYQEIAILKKLDHVNVVKLIEVLDDPAEDNLYLVFDLLRKGPVMEV-PCDKPFSEEQA 252
Query: 508 RFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCG 687
R Y+ ++LG++YLH ++I+HRD+K NL L DD HVKI DFG++ + E + + G
Sbjct: 253 RLYLRDVILGLEYLHCQKIVHRDIKPSNLLLGDDGHVKIADFGVSNQFEGNDAQLSSTAG 312
Query: 688 TPNYIAPEILT 720
TP ++APE ++
Sbjct: 313 TPAFMAPEAIS 323
>AF425232-1|AAN37386.1| 505|Homo sapiens CaMKK alpha protein
protein.
Length = 505
Score = 103 bits (246), Expect = 9e-22
Identities = 49/131 (37%), Positives = 82/131 (62%), Gaps = 2/131 (1%)
Frame = +1
Query: 334 EKMAQEISIHRSLQHKHVVGFHSFFEDSL--NIYIILELCKKRSMMELHKRRKAITEPET 507
E++ QEI+I + L H +VV +D N+Y++ +L +K +ME+ K +E +
Sbjct: 194 ERVYQEIAILKKLDHVNVVKLIEVLDDPAEDNLYLVFDLLRKGPVMEV-PCDKPFSEEQA 252
Query: 508 RFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCG 687
R Y+ ++LG++YLH ++I+HRD+K NL L DD HVKI DFG++ + E + + G
Sbjct: 253 RLYLRDVILGLEYLHCQKIVHRDIKPSNLLLGDDGHVKIADFGVSNQFEGNDAQLSSTAG 312
Query: 688 TPNYIAPEILT 720
TP ++APE ++
Sbjct: 313 TPAFMAPEAIS 323
>Y11950-1|CAA72694.1| 406|Homo sapiens phosphorylase kinase gamma
subunit protein.
Length = 406
Score = 102 bits (244), Expect = 2e-21
Identities = 47/129 (36%), Positives = 78/129 (60%), Gaps = 1/129 (0%)
Frame = +1
Query: 334 EKMAQEISIHRSLQ-HKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETR 510
E +E I R + H H++ +E S ++++ +L +K + + + A++E ETR
Sbjct: 72 EATRRETHILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYLTEKVALSEKETR 131
Query: 511 FYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGT 690
M +L V +LH+ I+HRDLK N+ LDD++ +++ DFG + +E GE+ + LCGT
Sbjct: 132 SIMRSLLEAVSFLHANNIVHRDLKPENILLDDNMQIRLSDFGFSCHLE-PGEKLRELCGT 190
Query: 691 PNYIAPEIL 717
P Y+APEIL
Sbjct: 191 PGYLAPEIL 199
>M95936-1|AAA58364.1| 481|Homo sapiens protein serine/threonine
kinase protein.
Length = 481
Score = 102 bits (244), Expect = 2e-21
Identities = 52/175 (29%), Positives = 85/175 (48%)
Frame = +1
Query: 193 TNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSL 372
T + + L+ GKG F K +++ A+ + YA E + ++
Sbjct: 148 TMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNT 207
Query: 373 QHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLH 552
+H + F+ + ++E + R + TE RFY +I+ ++YLH
Sbjct: 208 RHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSALEYLH 267
Query: 553 SKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEIL 717
S+ +++RD+KL NL LD D H+KI DFGL +G +T CGTP Y+APE+L
Sbjct: 268 SRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVL 322
>M77198-1|AAA36585.1| 520|Homo sapiens rac protein kinase-beta
protein.
Length = 520
Score = 102 bits (244), Expect = 2e-21
Identities = 52/175 (29%), Positives = 85/175 (48%)
Frame = +1
Query: 193 TNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSL 372
T + + L+ GKG F K +++ A+ + YA E + ++
Sbjct: 148 TMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNT 207
Query: 373 QHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLH 552
+H + F+ + ++E + R + TE RFY +I+ ++YLH
Sbjct: 208 RHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSALEYLH 267
Query: 553 SKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEIL 717
S+ +++RD+KL NL LD D H+KI DFGL +G +T CGTP Y+APE+L
Sbjct: 268 SRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVL 322
>M31606-1|AAA36442.1| 406|Homo sapiens phosphorylase kinase
protein.
Length = 406
Score = 102 bits (244), Expect = 2e-21
Identities = 47/129 (36%), Positives = 78/129 (60%), Gaps = 1/129 (0%)
Frame = +1
Query: 334 EKMAQEISIHRSLQ-HKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETR 510
E +E I R + H H++ +E S ++++ +L +K + + + A++E ETR
Sbjct: 72 EATRRETHILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYLTEKVALSEKETR 131
Query: 511 FYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGT 690
M +L V +LH+ I+HRDLK N+ LDD++ +++ DFG + +E GE+ + LCGT
Sbjct: 132 SIMRSLLEAVSFLHANNIVHRDLKPENILLDDNMQIRLSDFGFSCHLE-PGEKLRELCGT 190
Query: 691 PNYIAPEIL 717
P Y+APEIL
Sbjct: 191 PGYLAPEIL 199
>BC120994-1|AAI20995.1| 481|Homo sapiens v-akt murine thymoma viral
oncogene homolog 2 protein.
Length = 481
Score = 102 bits (244), Expect = 2e-21
Identities = 52/175 (29%), Positives = 85/175 (48%)
Frame = +1
Query: 193 TNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSL 372
T + + L+ GKG F K +++ A+ + YA E + ++
Sbjct: 148 TMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNT 207
Query: 373 QHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLH 552
+H + F+ + ++E + R + TE RFY +I+ ++YLH
Sbjct: 208 RHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSALEYLH 267
Query: 553 SKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEIL 717
S+ +++RD+KL NL LD D H+KI DFGL +G +T CGTP Y+APE+L
Sbjct: 268 SRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVL 322
>BC032709-1|AAH32709.1| 344|Homo sapiens AKT2 protein protein.
Length = 344
Score = 102 bits (244), Expect = 2e-21
Identities = 52/175 (29%), Positives = 85/175 (48%)
Frame = +1
Query: 193 TNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSL 372
T + + L+ GKG F K +++ A+ + YA E + ++
Sbjct: 148 TMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNT 207
Query: 373 QHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLH 552
+H + F+ + ++E + R + TE RFY +I+ ++YLH
Sbjct: 208 RHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSALEYLH 267
Query: 553 SKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEIL 717
S+ +++RD+KL NL LD D H+KI DFGL +G +T CGTP Y+APE+L
Sbjct: 268 SRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVL 322
>BC002541-1|AAH02541.1| 406|Homo sapiens phosphorylase kinase,
gamma 2 (testis) protein.
Length = 406
Score = 102 bits (244), Expect = 2e-21
Identities = 47/129 (36%), Positives = 78/129 (60%), Gaps = 1/129 (0%)
Frame = +1
Query: 334 EKMAQEISIHRSLQ-HKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETR 510
E +E I R + H H++ +E S ++++ +L +K + + + A++E ETR
Sbjct: 72 EATRRETHILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYLTEKVALSEKETR 131
Query: 511 FYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGT 690
M +L V +LH+ I+HRDLK N+ LDD++ +++ DFG + +E GE+ + LCGT
Sbjct: 132 SIMRSLLEAVSFLHANNIVHRDLKPENILLDDNMQIRLSDFGFSCHLE-PGEKLRELCGT 190
Query: 691 PNYIAPEIL 717
P Y+APEIL
Sbjct: 191 PGYLAPEIL 199
>BC121154-1|AAI21155.1| 465|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 465
Score = 101 bits (243), Expect = 2e-21
Identities = 54/179 (30%), Positives = 85/179 (47%)
Frame = +1
Query: 181 HDPQTNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISI 360
H +T + + L+ GKG F K +++ AS + YA E +
Sbjct: 140 HKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRV 199
Query: 361 HRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGV 540
++ +H + F+ + ++E + R + +E TRFY +I+ +
Sbjct: 200 LKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSAL 259
Query: 541 QYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEIL 717
YLHS +I++RDLKL NL D D H+KI DFGL + +T CGTP Y+APE+L
Sbjct: 260 DYLHSGKIVYRDLKLENLMRDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVL 318
>BC035058-1|AAH35058.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 351
Score = 101 bits (243), Expect = 2e-21
Identities = 57/174 (32%), Positives = 89/174 (51%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKH 384
++R + G G F + ++ A+ Q YA E E I +++
Sbjct: 44 FERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPF 103
Query: 385 VVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRI 564
+V F+D+ N+Y+++E M +R +EP RFY QI+L +YL+S I
Sbjct: 104 LVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLNSLDI 163
Query: 565 IHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
I+RDLK NL +D ++++ DFG A R++ R TLCGTP Y+APEI+ K
Sbjct: 164 IYRDLKPENLLIDHQGYIQVTDFGFAKRVK---GRTWTLCGTPEYLAPEIILSK 214
>BC031231-1|AAH31231.1| 514|Homo sapiens serine/threonine kinase 33
protein.
Length = 514
Score = 101 bits (242), Expect = 3e-21
Identities = 55/178 (30%), Positives = 95/178 (53%), Gaps = 10/178 (5%)
Frame = +1
Query: 217 RFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKHVVGF 396
R GKG F E D + +A + + +E++I +S++H+H++
Sbjct: 120 RILGKGSFGIVIEATDKETETKWA-IKKVNKEKAGSSAVKLLEREVNILKSVKHEHIIHL 178
Query: 397 HSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRIIHRD 576
FE +Y+++ELC+ + E+ R+ +E ETR+ + + + YLH+ I+HRD
Sbjct: 179 EQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDIVHRD 238
Query: 577 LKLGNL-----FLDD----DLHVKIGDFGLAARIEYEGERK-QTLCGTPNYIAPEILT 720
LKL N+ +DD +L++K+ DFGLA + + E Q CGTP Y+APE+++
Sbjct: 239 LKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMAPEVIS 296
>AL450063-9|CAI16852.1| 197|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 197
Score = 101 bits (242), Expect = 3e-21
Identities = 56/170 (32%), Positives = 87/170 (51%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKH 384
++R + G G F + ++ A+ Q YA E E I +++
Sbjct: 31 FERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPF 90
Query: 385 VVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRI 564
+V F+D+ N+Y+++E M +R +EP RFY QI+L +YLHS +
Sbjct: 91 LVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 150
Query: 565 IHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEI 714
I+RDLK NL +D ++++ DFG A R++ R TLCGTP Y+APEI
Sbjct: 151 IYRDLKPENLLIDHQGYIQVTDFGFAKRVK---GRTWTLCGTPEYLAPEI 197
>AK093251-1|BAC04109.1| 514|Homo sapiens protein ( Homo sapiens
cDNA FLJ35932 fis, clone TESTI2011286, weakly similar to
MYOSIN LIGHT CHAIN KINASE (EC 2.7.1.117). ).
Length = 514
Score = 101 bits (242), Expect = 3e-21
Identities = 55/178 (30%), Positives = 95/178 (53%), Gaps = 10/178 (5%)
Frame = +1
Query: 217 RFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKHVVGF 396
R GKG F E D + +A + + +E++I +S++H+H++
Sbjct: 120 RILGKGSFGIVIEATDKETETKWA-IKKVNKEKAGSSAVKLLEREVNILKSVKHEHIIHL 178
Query: 397 HSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRIIHRD 576
FE +Y+++ELC+ + E+ R+ +E ETR+ + + + YLH+ I+HRD
Sbjct: 179 EQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDIVHRD 238
Query: 577 LKLGNL-----FLDD----DLHVKIGDFGLAARIEYEGERK-QTLCGTPNYIAPEILT 720
LKL N+ +DD +L++K+ DFGLA + + E Q CGTP Y+APE+++
Sbjct: 239 LKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMAPEVIS 296
>AJ303380-1|CAC29064.1| 514|Homo sapiens serine/threonine kinase 33
protein.
Length = 514
Score = 101 bits (242), Expect = 3e-21
Identities = 55/178 (30%), Positives = 95/178 (53%), Gaps = 10/178 (5%)
Frame = +1
Query: 217 RFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKHVVGF 396
R GKG F E D + +A + + +E++I +S++H+H++
Sbjct: 120 RILGKGSFGIVIEATDKETETKWA-IKKVNKEKAGSSAVKLLEREVNILKSVKHEHIIHL 178
Query: 397 HSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRIIHRD 576
FE +Y+++ELC+ + E+ R+ +E ETR+ + + + YLH+ I+HRD
Sbjct: 179 EQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDIVHRD 238
Query: 577 LKLGNL-----FLDD----DLHVKIGDFGLAARIEYEGERK-QTLCGTPNYIAPEILT 720
LKL N+ +DD +L++K+ DFGLA + + E Q CGTP Y+APE+++
Sbjct: 239 LKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMAPEVIS 296
>X07767-1|CAA30597.1| 351|Homo sapiens protein ( Human mRNA for
cAMP-dependent protein kinase catalytic subunit type
alpha (EC 2.7.1.37). ).
Length = 351
Score = 101 bits (241), Expect = 3e-21
Identities = 55/174 (31%), Positives = 88/174 (50%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKH 384
++R++ G G F + ++ + YA E E I +++
Sbjct: 44 FERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPF 103
Query: 385 VVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRI 564
+V F+D+ N+Y+++E M +R +EP RFY QI+L +YLHS +
Sbjct: 104 LVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 163
Query: 565 IHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
I+RDLK NL +D ++++ DFG A R++ R TLCGTP Y+APEI+ K
Sbjct: 164 IYRDLKPENLLIDQQGYIQVTDFGFAKRVK---GRTWTLCGTPEYLAPEIILSK 214
>U64205-1|AAC15093.1| 729|Homo sapiens Cdc25C associated protein
kinase C-TAK1 protein.
Length = 729
Score = 101 bits (241), Expect = 3e-21
Identities = 57/174 (32%), Positives = 84/174 (48%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKH 384
Y+ L+ GKG FAK + I + + A +K+ +E+ I + L H +
Sbjct: 56 YRLLKTIGKGNFAKVKLARHILTGREVA-IKIIDKTQLNPTSLQKLFREVRIMKILNHPN 114
Query: 385 VVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRI 564
+V E +Y+I+E + + + E E R QI+ VQY H KRI
Sbjct: 115 IVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRI 174
Query: 565 IHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
+HRDLK NL LD D+++KI DFG + G + T CG+P Y APE+ K
Sbjct: 175 VHRDLKAENLLLDADMNIKIADFGFSNEFTV-GGKLDTFCGSPPYAAPELFQGK 227
>M80359-1|AAA59991.1| 713|Homo sapiens protein p78 protein.
Length = 713
Score = 101 bits (241), Expect = 3e-21
Identities = 57/174 (32%), Positives = 84/174 (48%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKH 384
Y+ L+ GKG FAK + I + + A +K+ +E+ I + L H +
Sbjct: 56 YRLLKTIGKGNFAKVKLARHILTGREVA-IKIIDKTQLNPTSLQKLFREVRIMKILNHPN 114
Query: 385 VVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRI 564
+V E +Y+I+E + + + E E R QI+ VQY H KRI
Sbjct: 115 IVKLFEVIETQKTLYLIMEYASGGKVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRI 174
Query: 565 IHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
+HRDLK NL LD D+++KI DFG + G + T CG+P Y APE+ K
Sbjct: 175 VHRDLKAENLLLDADMNIKIADFGFSNEFTV-GGKLDTFCGSPPYAAPELFQGK 227
>M80335-1|AAA60094.1| 207|Homo sapiens protein kinase A-alpha
protein.
Length = 207
Score = 101 bits (241), Expect = 3e-21
Identities = 55/174 (31%), Positives = 88/174 (50%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKH 384
++R++ G G F + ++ + YA E E I +++
Sbjct: 27 FERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPF 86
Query: 385 VVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRI 564
+V F+D+ N+Y+++E M +R +EP RFY QI+L +YLHS +
Sbjct: 87 LVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 146
Query: 565 IHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
I+RDLK NL +D ++++ DFG A R++ R TLCGTP Y+APEI+ K
Sbjct: 147 IYRDLKPENLLIDQQGYIQVTDFGFAKRVK---GRTWTLCGTPEYLAPEIILSK 197
>DQ667173-1|ABG25918.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, alpha protein.
Length = 351
Score = 101 bits (241), Expect = 3e-21
Identities = 55/174 (31%), Positives = 88/174 (50%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKH 384
++R++ G G F + ++ + YA E E I +++
Sbjct: 44 FERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPF 103
Query: 385 VVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRI 564
+V F+D+ N+Y+++E M +R +EP RFY QI+L +YLHS +
Sbjct: 104 LVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 163
Query: 565 IHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
I+RDLK NL +D ++++ DFG A R++ R TLCGTP Y+APEI+ K
Sbjct: 164 IYRDLKPENLLIDQQGYIQVTDFGFAKRVK---GRTWTLCGTPEYLAPEIILSK 214
>BC108259-1|AAI08260.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, alpha protein.
Length = 351
Score = 101 bits (241), Expect = 3e-21
Identities = 55/174 (31%), Positives = 88/174 (50%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKH 384
++R++ G G F + ++ + YA E E I +++
Sbjct: 44 FERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPF 103
Query: 385 VVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRI 564
+V F+D+ N+Y+++E M +R +EP RFY QI+L +YLHS +
Sbjct: 104 LVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 163
Query: 565 IHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
I+RDLK NL +D ++++ DFG A R++ R TLCGTP Y+APEI+ K
Sbjct: 164 IYRDLKPENLLIDQQGYIQVTDFGFAKRVK---GRTWTLCGTPEYLAPEIILSK 214
>BC039846-1|AAH39846.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, alpha protein.
Length = 351
Score = 101 bits (241), Expect = 3e-21
Identities = 55/174 (31%), Positives = 88/174 (50%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKH 384
++R++ G G F + ++ + YA E E I +++
Sbjct: 44 FERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPF 103
Query: 385 VVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRI 564
+V F+D+ N+Y+++E M +R +EP RFY QI+L +YLHS +
Sbjct: 104 LVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 163
Query: 565 IHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
I+RDLK NL +D ++++ DFG A R++ R TLCGTP Y+APEI+ K
Sbjct: 164 IYRDLKPENLLIDQQGYIQVTDFGFAKRVK---GRTWTLCGTPEYLAPEIILSK 214
>BC024773-1|AAH24773.1| 729|Homo sapiens MAP/microtubule
affinity-regulating kinase 3 protein.
Length = 729
Score = 101 bits (241), Expect = 3e-21
Identities = 57/174 (32%), Positives = 84/174 (48%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKH 384
Y+ L+ GKG FAK + I + + A +K+ +E+ I + L H +
Sbjct: 56 YRLLKTIGKGNFAKVKLARHILTGREVA-IKIIDKTQLNPTSLQKLFREVRIMKILNHPN 114
Query: 385 VVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRI 564
+V E +Y+I+E + + + E E R QI+ VQY H KRI
Sbjct: 115 IVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRI 174
Query: 565 IHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
+HRDLK NL LD D+++KI DFG + G + T CG+P Y APE+ K
Sbjct: 175 VHRDLKAENLLLDADMNIKIADFGFSNEFTV-GGKLDTFCGSPPYAAPELFQGK 227
>AF465413-1|AAL69982.1| 753|Homo sapiens MAP/microtubule
affinity-regulating kinase 3 long isoform protein.
Length = 753
Score = 101 bits (241), Expect = 3e-21
Identities = 57/174 (32%), Positives = 84/174 (48%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKH 384
Y+ L+ GKG FAK + I + + A +K+ +E+ I + L H +
Sbjct: 56 YRLLKTIGKGNFAKVKLARHILTGREVA-IKIIDKTQLNPTSLQKLFREVRIMKILNHPN 114
Query: 385 VVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRI 564
+V E +Y+I+E + + + E E R QI+ VQY H KRI
Sbjct: 115 IVKLFEVIETEKTLYLIMEYASGGKVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRI 174
Query: 565 IHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
+HRDLK NL LD D+++KI DFG + G + T CG+P Y APE+ K
Sbjct: 175 VHRDLKAENLLLDADMNIKIADFGFSNEFTV-GGKLDTFCGSPPYAAPELFQGK 227
>AF387637-1|AAK82367.1| 744|Homo sapiens Ser/Thr protein kinase
PAR-1A protein.
Length = 744
Score = 101 bits (241), Expect = 3e-21
Identities = 57/174 (32%), Positives = 84/174 (48%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKH 384
Y+ L+ GKG FAK + I + + A +K+ +E+ I + L H +
Sbjct: 56 YRLLKTIGKGNFAKVKLARHILTGREVA-IKIIDKTQLNPTSLQKLFREVRIMKILNHPN 114
Query: 385 VVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRI 564
+V E +Y+I+E + + + E E R QI+ VQY H KRI
Sbjct: 115 IVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRI 174
Query: 565 IHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
+HRDLK NL LD D+++KI DFG + G + T CG+P Y APE+ K
Sbjct: 175 VHRDLKAENLLLDADMNIKIADFGFSNEFTV-GGKLDTFCGSPPYAAPELFQGK 227
>BC019916-1|AAH19916.2| 506|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 3 protein.
Length = 506
Score = 100 bits (239), Expect = 6e-21
Identities = 55/172 (31%), Positives = 88/172 (51%), Gaps = 2/172 (1%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKH 384
Y LR G+G F + +Q +SNQ++A + +E + ++H +
Sbjct: 4 YMVLRMIGEGSFGRALLVQHESSNQMFA--MKEIRLPKSFSNTQNSRKEAVLLAKMKHPN 61
Query: 385 VVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRF--YMHQILLGVQYLHSK 558
+V F FE ++YI++E C +M+ K++K PE + Q+ LGV ++H K
Sbjct: 62 IVAFKESFEAEGHLYIVMEYCDGGDLMQKIKQQKGKLFPEDMILNWFTQMCLGVNHIHKK 121
Query: 559 RIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEI 714
R++HRD+K N+FL + VK+GDFG A + T GTP Y+ PEI
Sbjct: 122 RVLHRDIKSKNIFLTQNGKVKLGDFGSARLLSNPMAFACTYVGTPYYVPPEI 173
>AL139082-7|CAI12895.1| 507|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 3 protein.
Length = 507
Score = 100 bits (239), Expect = 6e-21
Identities = 55/172 (31%), Positives = 88/172 (51%), Gaps = 2/172 (1%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKH 384
Y LR G+G F + +Q +SNQ++A + +E + ++H +
Sbjct: 4 YMVLRMIGEGSFGRALLVQHESSNQMFA--MKEIRLPKSFSNTQNSRKEAVLLAKMKHPN 61
Query: 385 VVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRF--YMHQILLGVQYLHSK 558
+V F FE ++YI++E C +M+ K++K PE + Q+ LGV ++H K
Sbjct: 62 IVAFKESFEAEGHLYIVMEYCDGGDLMQKIKQQKGKLFPEDMILNWFTQMCLGVNHIHKK 121
Query: 559 RIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEI 714
R++HRD+K N+FL + VK+GDFG A + T GTP Y+ PEI
Sbjct: 122 RVLHRDIKSKNIFLTQNGKVKLGDFGSARLLSNPMAFACTYVGTPYYVPPEI 173
>AK131359-1|BAD18511.1| 510|Homo sapiens protein ( Homo sapiens
cDNA FLJ16392 fis, clone TRACH2020048, moderately
similar to Mus musculus serine/threonine-protein kinase
NEK3 (Nek3) mRNA. ).
Length = 510
Score = 100 bits (239), Expect = 6e-21
Identities = 55/172 (31%), Positives = 88/172 (51%), Gaps = 2/172 (1%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKH 384
Y LR G+G F + +Q +SNQ++A + +E + ++H +
Sbjct: 25 YMVLRMIGEGSFGRALLVQHESSNQMFA--MKEIRLPKSFSNTQNSRKEAVLLAKMKHPN 82
Query: 385 VVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRF--YMHQILLGVQYLHSK 558
+V F FE ++YI++E C +M+ K++K PE + Q+ LGV ++H K
Sbjct: 83 IVAFKESFEAEGHLYIVMEYCDGGDLMQKIKQQKGKLFPEDMILNWFTQMCLGVNHIHKK 142
Query: 559 RIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEI 714
R++HRD+K N+FL + VK+GDFG A + T GTP Y+ PEI
Sbjct: 143 RVLHRDIKSKNIFLTQNGKVKLGDFGSARLLSNPMAFACTYVGTPYYVPPEI 194
>X97630-1|CAA66229.1| 745|Homo sapiens serine/threonine protein
kinase protein.
Length = 745
Score = 99 bits (238), Expect = 8e-21
Identities = 55/174 (31%), Positives = 84/174 (48%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKH 384
Y+ L+ GKG FAK + I + + A +K+ +E+ I + L H +
Sbjct: 20 YRLLKTIGKGNFAKVKLARHILTGKEVA-VKIIDKTQLNSSSLQKLFREVRIMKVLNHPN 78
Query: 385 VVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRI 564
+V E +Y+++E + + + E E R QI+ VQY H K I
Sbjct: 79 IVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFI 138
Query: 565 IHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
+HRDLK NL LD D+++KI DFG + + G + T CG+P Y APE+ K
Sbjct: 139 VHRDLKAENLLLDADMNIKIADFGFSNEFTF-GNKLDTFCGSPPYAAPELFQGK 191
>BT007342-1|AAP36006.1| 755|Homo sapiens MAP/microtubule
affinity-regulating kinase 2 protein.
Length = 755
Score = 99 bits (238), Expect = 8e-21
Identities = 55/174 (31%), Positives = 84/174 (48%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKH 384
Y+ L+ GKG FAK + I + + A +K+ +E+ I + L H +
Sbjct: 20 YRLLKTIGKGNFAKVKLARHILTGKEVA-VKIIDKTQLNSSSLQKLFREVRIMKVLNHPN 78
Query: 385 VVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRI 564
+V E +Y+++E + + + E E R QI+ VQY H K I
Sbjct: 79 IVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFI 138
Query: 565 IHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
+HRDLK NL LD D+++KI DFG + + G + T CG+P Y APE+ K
Sbjct: 139 VHRDLKAENLLLDADMNIKIADFGFSNEFTF-GNKLDTFCGSPPYAAPELFQGK 191
>BC084540-1|AAH84540.1| 724|Homo sapiens MAP/microtubule
affinity-regulating kinase 2 protein.
Length = 724
Score = 99 bits (238), Expect = 8e-21
Identities = 55/174 (31%), Positives = 84/174 (48%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKH 384
Y+ L+ GKG FAK + I + + A +K+ +E+ I + L H +
Sbjct: 53 YRLLKTIGKGNFAKVKLARHILTGKEVA-VKIIDKTQLNSSSLQKLFREVRIMKVLNHPN 111
Query: 385 VVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRI 564
+V E +Y+++E + + + E E R QI+ VQY H K I
Sbjct: 112 IVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFI 171
Query: 565 IHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
+HRDLK NL LD D+++KI DFG + + G + T CG+P Y APE+ K
Sbjct: 172 VHRDLKAENLLLDADMNIKIADFGFSNEFTF-GNKLDTFCGSPPYAAPELFQGK 224
>BC008771-1|AAH08771.2| 778|Homo sapiens MARK2 protein protein.
Length = 778
Score = 99 bits (238), Expect = 8e-21
Identities = 55/174 (31%), Positives = 84/174 (48%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKH 384
Y+ L+ GKG FAK + I + + A +K+ +E+ I + L H +
Sbjct: 43 YRLLKTIGKGNFAKVKLARHILTGKEVA-VKIIDKTQLNSSSLQKLFREVRIMKVLNHPN 101
Query: 385 VVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRI 564
+V E +Y+++E + + + E E R QI+ VQY H K I
Sbjct: 102 IVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFI 161
Query: 565 IHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
+HRDLK NL LD D+++KI DFG + + G + T CG+P Y APE+ K
Sbjct: 162 VHRDLKAENLLLDADMNIKIADFGFSNEFTF-GNKLDTFCGSPPYAAPELFQGK 214
>AF387638-1|AAK82368.1| 691|Homo sapiens Ser/Thr protein kinase
PAR-1Balpha protein.
Length = 691
Score = 99 bits (238), Expect = 8e-21
Identities = 55/174 (31%), Positives = 84/174 (48%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKH 384
Y+ L+ GKG FAK + I + + A +K+ +E+ I + L H +
Sbjct: 20 YRLLKTIGKGNFAKVKLARHILTGKEVA-VKIIDKTQLNSSSLQKLFREVRIMKVLNHPN 78
Query: 385 VVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRI 564
+V E +Y+++E + + + E E R QI+ VQY H K I
Sbjct: 79 IVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFI 138
Query: 565 IHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
+HRDLK NL LD D+++KI DFG + + G + T CG+P Y APE+ K
Sbjct: 139 VHRDLKAENLLLDADMNIKIADFGFSNEFTF-GNKLDTFCGSPPYAAPELFQGK 191
>AB188493-1|BAD37141.1| 719|Homo sapiens serine/threonine kinase
protein.
Length = 719
Score = 99 bits (238), Expect = 8e-21
Identities = 55/174 (31%), Positives = 84/174 (48%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKH 384
Y+ L+ GKG FAK + I + + A +K+ +E+ I + L H +
Sbjct: 53 YRLLKTIGKGNFAKVKLARHILTGKEVA-VKIIDKTQLNSSSLQKLFREVRIMKVLNHPN 111
Query: 385 VVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRI 564
+V E +Y+++E + + + E E R QI+ VQY H K I
Sbjct: 112 IVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFI 171
Query: 565 IHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
+HRDLK NL LD D+++KI DFG + + G + T CG+P Y APE+ K
Sbjct: 172 VHRDLKAENLLLDADMNIKIADFGFSNEFTF-GNKLDTFCGSPPYAAPELFQGK 224
>AB072828-1|BAC15599.1| 489|Homo sapiens NIMA-related protein
kinase 3 protein.
Length = 489
Score = 99.1 bits (236), Expect = 1e-20
Identities = 55/172 (31%), Positives = 88/172 (51%), Gaps = 2/172 (1%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKH 384
Y LR G+G F + +Q +SNQ++A + +E + ++H +
Sbjct: 4 YMVLRMIGEGFFGRALLVQHESSNQMFA--MKEIRLPKSFSNTQNSRKEAVLLAKMKHPN 61
Query: 385 VVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRF--YMHQILLGVQYLHSK 558
+V F FE ++YI++E C +M+ K++K PE + Q+ LGV ++H K
Sbjct: 62 IVAFKESFEAEGHLYIVMEYCDGGDLMQKIKQQKGKLFPEDMILNWFTQMCLGVNHIHKK 121
Query: 559 RIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEI 714
R++HRD+K N+FL + VK+GDFG A + T GTP Y+ PEI
Sbjct: 122 RVLHRDIKSKNIFLTQNGKVKLGDFGSARLLSNPMAFACTYVGTPYYVPPEI 173
>Z84486-1|CAI21678.1| 526|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 526
Score = 98.3 bits (234), Expect = 2e-20
Identities = 53/177 (29%), Positives = 83/177 (46%), Gaps = 1/177 (0%)
Frame = +1
Query: 199 STYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIH-RSLQ 375
S + L+ GKG F K + A YA + + E ++ ++++
Sbjct: 191 SDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVK 250
Query: 376 HKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHS 555
H +VG H F+ + +Y +L+ + +R + EP RFY +I + YLHS
Sbjct: 251 HPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHS 310
Query: 556 KRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
I++RDLK N+ LD H+ + DFGL T CGTP Y+APE+L K+
Sbjct: 311 LNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQ 367
>Y10032-1|CAA71138.1| 431|Homo sapiens serine/threonine protein
kinase protein.
Length = 431
Score = 98.3 bits (234), Expect = 2e-20
Identities = 53/177 (29%), Positives = 83/177 (46%), Gaps = 1/177 (0%)
Frame = +1
Query: 199 STYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIH-RSLQ 375
S + L+ GKG F K + A YA + + E ++ ++++
Sbjct: 96 SDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVK 155
Query: 376 HKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHS 555
H +VG H F+ + +Y +L+ + +R + EP RFY +I + YLHS
Sbjct: 156 HPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHS 215
Query: 556 KRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
I++RDLK N+ LD H+ + DFGL T CGTP Y+APE+L K+
Sbjct: 216 LNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQ 272
>BC126432-1|AAI26433.1| 454|Homo sapiens death-associated protein
kinase 3 protein.
Length = 454
Score = 98.3 bits (234), Expect = 2e-20
Identities = 49/132 (37%), Positives = 82/132 (62%), Gaps = 4/132 (3%)
Frame = +1
Query: 334 EKMAQEISIHRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRF 513
E++ +E++I R ++H +++ H FE+ ++ +ILEL + + ++++TE E
Sbjct: 59 EEIEREVNILREIRHPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQ 118
Query: 514 YMHQILLGVQYLHSKRIIHRDLKLGNLFLDD----DLHVKIGDFGLAARIEYEGERKQTL 681
++ QIL GV YLHSKRI H DLK N+ L D + +K+ DFG+A +IE G + +
Sbjct: 119 FLKQILDGVHYLHSKRIAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIE-AGNEFKNI 177
Query: 682 CGTPNYIAPEIL 717
GTP ++APEI+
Sbjct: 178 FGTPEFVAPEIV 189
>BC126430-1|AAI26431.1| 454|Homo sapiens death-associated protein
kinase 3 protein.
Length = 454
Score = 98.3 bits (234), Expect = 2e-20
Identities = 49/132 (37%), Positives = 82/132 (62%), Gaps = 4/132 (3%)
Frame = +1
Query: 334 EKMAQEISIHRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRF 513
E++ +E++I R ++H +++ H FE+ ++ +ILEL + + ++++TE E
Sbjct: 59 EEIEREVNILREIRHPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQ 118
Query: 514 YMHQILLGVQYLHSKRIIHRDLKLGNLFLDD----DLHVKIGDFGLAARIEYEGERKQTL 681
++ QIL GV YLHSKRI H DLK N+ L D + +K+ DFG+A +IE G + +
Sbjct: 119 FLKQILDGVHYLHSKRIAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIE-AGNEFKNI 177
Query: 682 CGTPNYIAPEIL 717
GTP ++APEI+
Sbjct: 178 FGTPEFVAPEIV 189
>BC001263-1|AAH01263.1| 431|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 431
Score = 98.3 bits (234), Expect = 2e-20
Identities = 53/177 (29%), Positives = 83/177 (46%), Gaps = 1/177 (0%)
Frame = +1
Query: 199 STYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIH-RSLQ 375
S + L+ GKG F K + A YA + + E ++ ++++
Sbjct: 96 SDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVK 155
Query: 376 HKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHS 555
H +VG H F+ + +Y +L+ + +R + EP RFY +I + YLHS
Sbjct: 156 HPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHS 215
Query: 556 KRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
I++RDLK N+ LD H+ + DFGL T CGTP Y+APE+L K+
Sbjct: 216 LNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQ 272
>AL355881-2|CAH72579.1| 526|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 526
Score = 98.3 bits (234), Expect = 2e-20
Identities = 53/177 (29%), Positives = 83/177 (46%), Gaps = 1/177 (0%)
Frame = +1
Query: 199 STYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIH-RSLQ 375
S + L+ GKG F K + A YA + + E ++ ++++
Sbjct: 191 SDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVK 250
Query: 376 HKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHS 555
H +VG H F+ + +Y +L+ + +R + EP RFY +I + YLHS
Sbjct: 251 HPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHS 310
Query: 556 KRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
I++RDLK N+ LD H+ + DFGL T CGTP Y+APE+L K+
Sbjct: 311 LNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQ 367
>AL135839-4|CAI19721.1| 526|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 526
Score = 98.3 bits (234), Expect = 2e-20
Identities = 53/177 (29%), Positives = 83/177 (46%), Gaps = 1/177 (0%)
Frame = +1
Query: 199 STYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIH-RSLQ 375
S + L+ GKG F K + A YA + + E ++ ++++
Sbjct: 191 SDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVK 250
Query: 376 HKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHS 555
H +VG H F+ + +Y +L+ + +R + EP RFY +I + YLHS
Sbjct: 251 HPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHS 310
Query: 556 KRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
I++RDLK N+ LD H+ + DFGL T CGTP Y+APE+L K+
Sbjct: 311 LNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQ 367
>AL135839-3|CAI19720.1| 445|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 445
Score = 98.3 bits (234), Expect = 2e-20
Identities = 53/177 (29%), Positives = 83/177 (46%), Gaps = 1/177 (0%)
Frame = +1
Query: 199 STYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIH-RSLQ 375
S + L+ GKG F K + A YA + + E ++ ++++
Sbjct: 110 SDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVK 169
Query: 376 HKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHS 555
H +VG H F+ + +Y +L+ + +R + EP RFY +I + YLHS
Sbjct: 170 HPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHS 229
Query: 556 KRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
I++RDLK N+ LD H+ + DFGL T CGTP Y+APE+L K+
Sbjct: 230 LNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQ 286
>AL135839-2|CAI19719.1| 431|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 431
Score = 98.3 bits (234), Expect = 2e-20
Identities = 53/177 (29%), Positives = 83/177 (46%), Gaps = 1/177 (0%)
Frame = +1
Query: 199 STYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIH-RSLQ 375
S + L+ GKG F K + A YA + + E ++ ++++
Sbjct: 96 SDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVK 155
Query: 376 HKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHS 555
H +VG H F+ + +Y +L+ + +R + EP RFY +I + YLHS
Sbjct: 156 HPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHS 215
Query: 556 KRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
I++RDLK N+ LD H+ + DFGL T CGTP Y+APE+L K+
Sbjct: 216 LNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQ 272
>AL135839-1|CAI19718.1| 421|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 421
Score = 98.3 bits (234), Expect = 2e-20
Identities = 53/177 (29%), Positives = 83/177 (46%), Gaps = 1/177 (0%)
Frame = +1
Query: 199 STYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIH-RSLQ 375
S + L+ GKG F K + A YA + + E ++ ++++
Sbjct: 86 SDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVK 145
Query: 376 HKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHS 555
H +VG H F+ + +Y +L+ + +R + EP RFY +I + YLHS
Sbjct: 146 HPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHS 205
Query: 556 KRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
I++RDLK N+ LD H+ + DFGL T CGTP Y+APE+L K+
Sbjct: 206 LNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQ 262
>AJ000512-1|CAA04146.1| 431|Homo sapiens serine/threonine protein
kinase protein.
Length = 431
Score = 98.3 bits (234), Expect = 2e-20
Identities = 53/177 (29%), Positives = 83/177 (46%), Gaps = 1/177 (0%)
Frame = +1
Query: 199 STYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIH-RSLQ 375
S + L+ GKG F K + A YA + + E ++ ++++
Sbjct: 96 SDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVK 155
Query: 376 HKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHS 555
H +VG H F+ + +Y +L+ + +R + EP RFY +I + YLHS
Sbjct: 156 HPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHS 215
Query: 556 KRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
I++RDLK N+ LD H+ + DFGL T CGTP Y+APE+L K+
Sbjct: 216 LNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQ 272
>AF153609-1|AAD41091.1| 431|Homo sapiens serine/threonine protein
kinase sgk protein.
Length = 431
Score = 98.3 bits (234), Expect = 2e-20
Identities = 53/177 (29%), Positives = 83/177 (46%), Gaps = 1/177 (0%)
Frame = +1
Query: 199 STYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIH-RSLQ 375
S + L+ GKG F K + A YA + + E ++ ++++
Sbjct: 96 SDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVK 155
Query: 376 HKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHS 555
H +VG H F+ + +Y +L+ + +R + EP RFY +I + YLHS
Sbjct: 156 HPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHS 215
Query: 556 KRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
I++RDLK N+ LD H+ + DFGL T CGTP Y+APE+L K+
Sbjct: 216 LNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQ 272
>AB022341-1|BAA81746.1| 454|Homo sapiens ZIP kinase protein.
Length = 454
Score = 98.3 bits (234), Expect = 2e-20
Identities = 49/132 (37%), Positives = 82/132 (62%), Gaps = 4/132 (3%)
Frame = +1
Query: 334 EKMAQEISIHRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRF 513
E++ +E++I R ++H +++ H FE+ ++ +ILEL + + ++++TE E
Sbjct: 59 EEIEREVNILREIRHPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQ 118
Query: 514 YMHQILLGVQYLHSKRIIHRDLKLGNLFLDD----DLHVKIGDFGLAARIEYEGERKQTL 681
++ QIL GV YLHSKRI H DLK N+ L D + +K+ DFG+A +IE G + +
Sbjct: 119 FLKQILDGVHYLHSKRIAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIE-AGNEFKNI 177
Query: 682 CGTPNYIAPEIL 717
GTP ++APEI+
Sbjct: 178 FGTPEFVAPEIV 189
>AB007144-1|BAA24955.1| 454|Homo sapiens ZIP-kinase protein.
Length = 454
Score = 98.3 bits (234), Expect = 2e-20
Identities = 49/132 (37%), Positives = 82/132 (62%), Gaps = 4/132 (3%)
Frame = +1
Query: 334 EKMAQEISIHRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRF 513
E++ +E++I R ++H +++ H FE+ ++ +ILEL + + ++++TE E
Sbjct: 59 EEIEREVNILREIRHPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQ 118
Query: 514 YMHQILLGVQYLHSKRIIHRDLKLGNLFLDD----DLHVKIGDFGLAARIEYEGERKQTL 681
++ QIL GV YLHSKRI H DLK N+ L D + +K+ DFG+A +IE G + +
Sbjct: 119 FLKQILDGVHYLHSKRIAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIE-AGNEFKNI 177
Query: 682 CGTPNYIAPEIL 717
GTP ++APEI+
Sbjct: 178 FGTPEFVAPEIV 189
>M63167-1|AAA36539.1| 480|Homo sapiens rac protein kinase-alpha
protein.
Length = 480
Score = 97.9 bits (233), Expect = 3e-20
Identities = 53/176 (30%), Positives = 85/176 (48%), Gaps = 1/176 (0%)
Frame = +1
Query: 193 TNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSL 372
T + ++ L+ GKG F K +++ A+ + YA E + ++
Sbjct: 146 TMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNS 205
Query: 373 QHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLH 552
+H + F+ + ++E + R + +E RFY +I+ + YLH
Sbjct: 206 RHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLH 265
Query: 553 S-KRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEIL 717
S K +++RDLKL NL LD D H+KI DFGL +G +T CGTP Y+APE+L
Sbjct: 266 SEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVL 321
>L07032-1|AAA60101.1| 706|Homo sapiens protein kinase C-theta
protein.
Length = 706
Score = 97.9 bits (233), Expect = 3e-20
Identities = 53/168 (31%), Positives = 82/168 (48%), Gaps = 1/168 (0%)
Frame = +1
Query: 217 RFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXE-KMAQEISIHRSLQHKHVVG 393
+ GKG F K + + +NQ +A E M ++ + + +H +
Sbjct: 384 KMLGKGSFGKVFLAEFKKTNQFFAIKALKKDVVLMDDDVECTMVEKRVLSLAWEHPFLTH 443
Query: 394 FHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRIIHR 573
F+ N++ ++E +M + FY +I+LG+Q+LHSK I++R
Sbjct: 444 MFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFLHSKGIVYR 503
Query: 574 DLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEIL 717
DLKL N+ LD D H+KI DFG+ + T CGTP+YIAPEIL
Sbjct: 504 DLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEIL 551
>L01087-1|AAA75571.1| 706|Homo sapiens protein kinase C-theta
protein.
Length = 706
Score = 97.9 bits (233), Expect = 3e-20
Identities = 53/168 (31%), Positives = 82/168 (48%), Gaps = 1/168 (0%)
Frame = +1
Query: 217 RFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXE-KMAQEISIHRSLQHKHVVG 393
+ GKG F K + + +NQ +A E M ++ + + +H +
Sbjct: 384 KMLGKGSFGKVFLAEFKKTNQFFAIKALKKDVVLMDDDVECTMVEKRVLSLAWEHPFLTH 443
Query: 394 FHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRIIHR 573
F+ N++ ++E +M + FY +I+LG+Q+LHSK I++R
Sbjct: 444 MFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFLHSKGIVYR 503
Query: 574 DLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEIL 717
DLKL N+ LD D H+KI DFG+ + T CGTP+YIAPEIL
Sbjct: 504 DLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEIL 551
>BC113359-1|AAI13360.1| 706|Homo sapiens protein kinase C, theta
protein.
Length = 706
Score = 97.9 bits (233), Expect = 3e-20
Identities = 53/168 (31%), Positives = 82/168 (48%), Gaps = 1/168 (0%)
Frame = +1
Query: 217 RFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXE-KMAQEISIHRSLQHKHVVG 393
+ GKG F K + + +NQ +A E M ++ + + +H +
Sbjct: 384 KMLGKGSFGKVFLAEFKKTNQFFAIKALKKDVVLMDDDVECTMVEKRVLSLAWEHPFLTH 443
Query: 394 FHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRIIHR 573
F+ N++ ++E +M + FY +I+LG+Q+LHSK I++R
Sbjct: 444 MFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFLHSKGIVYR 503
Query: 574 DLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEIL 717
DLKL N+ LD D H+KI DFG+ + T CGTP+YIAPEIL
Sbjct: 504 DLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEIL 551
>BC101465-1|AAI01466.1| 706|Homo sapiens protein kinase C, theta
protein.
Length = 706
Score = 97.9 bits (233), Expect = 3e-20
Identities = 53/168 (31%), Positives = 82/168 (48%), Gaps = 1/168 (0%)
Frame = +1
Query: 217 RFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXE-KMAQEISIHRSLQHKHVVG 393
+ GKG F K + + +NQ +A E M ++ + + +H +
Sbjct: 384 KMLGKGSFGKVFLAEFKKTNQFFAIKALKKDVVLMDDDVECTMVEKRVLSLAWEHPFLTH 443
Query: 394 FHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRIIHR 573
F+ N++ ++E +M + FY +I+LG+Q+LHSK I++R
Sbjct: 444 MFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFLHSKGIVYR 503
Query: 574 DLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEIL 717
DLKL N+ LD D H+KI DFG+ + T CGTP+YIAPEIL
Sbjct: 504 DLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEIL 551
>BC084538-1|AAH84538.1| 480|Homo sapiens v-akt murine thymoma viral
oncogene homolog 1 protein.
Length = 480
Score = 97.9 bits (233), Expect = 3e-20
Identities = 53/176 (30%), Positives = 85/176 (48%), Gaps = 1/176 (0%)
Frame = +1
Query: 193 TNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSL 372
T + ++ L+ GKG F K +++ A+ + YA E + ++
Sbjct: 146 TMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNS 205
Query: 373 QHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLH 552
+H + F+ + ++E + R + +E RFY +I+ + YLH
Sbjct: 206 RHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLH 265
Query: 553 S-KRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEIL 717
S K +++RDLKL NL LD D H+KI DFGL +G +T CGTP Y+APE+L
Sbjct: 266 SEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVL 321
>BC000479-1|AAH00479.1| 480|Homo sapiens v-akt murine thymoma viral
oncogene homolog 1 protein.
Length = 480
Score = 97.9 bits (233), Expect = 3e-20
Identities = 53/176 (30%), Positives = 85/176 (48%), Gaps = 1/176 (0%)
Frame = +1
Query: 193 TNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSL 372
T + ++ L+ GKG F K +++ A+ + YA E + ++
Sbjct: 146 TMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNS 205
Query: 373 QHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLH 552
+H + F+ + ++E + R + +E RFY +I+ + YLH
Sbjct: 206 RHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLH 265
Query: 553 S-KRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEIL 717
S K +++RDLKL NL LD D H+KI DFGL +G +T CGTP Y+APE+L
Sbjct: 266 SEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVL 321
>AL158043-2|CAC12904.2| 706|Homo sapiens protein kinase C, theta
protein.
Length = 706
Score = 97.9 bits (233), Expect = 3e-20
Identities = 53/168 (31%), Positives = 82/168 (48%), Gaps = 1/168 (0%)
Frame = +1
Query: 217 RFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXE-KMAQEISIHRSLQHKHVVG 393
+ GKG F K + + +NQ +A E M ++ + + +H +
Sbjct: 384 KMLGKGSFGKVFLAEFKKTNQFFAIKALKKDVVLMDDDVECTMVEKRVLSLAWEHPFLTH 443
Query: 394 FHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRIIHR 573
F+ N++ ++E +M + FY +I+LG+Q+LHSK I++R
Sbjct: 444 MFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFLHSKGIVYR 503
Query: 574 DLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEIL 717
DLKL N+ LD D H+KI DFG+ + T CGTP+YIAPEIL
Sbjct: 504 DLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEIL 551
>AL158043-1|CAI16127.1| 478|Homo sapiens protein kinase C, theta
protein.
Length = 478
Score = 97.9 bits (233), Expect = 3e-20
Identities = 53/168 (31%), Positives = 82/168 (48%), Gaps = 1/168 (0%)
Frame = +1
Query: 217 RFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXE-KMAQEISIHRSLQHKHVVG 393
+ GKG F K + + +NQ +A E M ++ + + +H +
Sbjct: 156 KMLGKGSFGKVFLAEFKKTNQFFAIKALKKDVVLMDDDVECTMVEKRVLSLAWEHPFLTH 215
Query: 394 FHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRIIHR 573
F+ N++ ++E +M + FY +I+LG+Q+LHSK I++R
Sbjct: 216 MFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFLHSKGIVYR 275
Query: 574 DLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEIL 717
DLKL N+ LD D H+KI DFG+ + T CGTP+YIAPEIL
Sbjct: 276 DLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEIL 323
>AL137145-2|CAC10200.2| 706|Homo sapiens protein kinase C, theta
protein.
Length = 706
Score = 97.9 bits (233), Expect = 3e-20
Identities = 53/168 (31%), Positives = 82/168 (48%), Gaps = 1/168 (0%)
Frame = +1
Query: 217 RFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXE-KMAQEISIHRSLQHKHVVG 393
+ GKG F K + + +NQ +A E M ++ + + +H +
Sbjct: 384 KMLGKGSFGKVFLAEFKKTNQFFAIKALKKDVVLMDDDVECTMVEKRVLSLAWEHPFLTH 443
Query: 394 FHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRIIHR 573
F+ N++ ++E +M + FY +I+LG+Q+LHSK I++R
Sbjct: 444 MFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFLHSKGIVYR 503
Query: 574 DLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEIL 717
DLKL N+ LD D H+KI DFG+ + T CGTP+YIAPEIL
Sbjct: 504 DLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEIL 551
>AL137145-1|CAI15756.1| 478|Homo sapiens protein kinase C, theta
protein.
Length = 478
Score = 97.9 bits (233), Expect = 3e-20
Identities = 53/168 (31%), Positives = 82/168 (48%), Gaps = 1/168 (0%)
Frame = +1
Query: 217 RFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXE-KMAQEISIHRSLQHKHVVG 393
+ GKG F K + + +NQ +A E M ++ + + +H +
Sbjct: 156 KMLGKGSFGKVFLAEFKKTNQFFAIKALKKDVVLMDDDVECTMVEKRVLSLAWEHPFLTH 215
Query: 394 FHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRIIHR 573
F+ N++ ++E +M + FY +I+LG+Q+LHSK I++R
Sbjct: 216 MFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFLHSKGIVYR 275
Query: 574 DLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEIL 717
DLKL N+ LD D H+KI DFG+ + T CGTP+YIAPEIL
Sbjct: 276 DLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEIL 323
>AF283830-1|AAL55732.1| 480|Homo sapiens AKT1 protein.
Length = 480
Score = 97.9 bits (233), Expect = 3e-20
Identities = 53/176 (30%), Positives = 85/176 (48%), Gaps = 1/176 (0%)
Frame = +1
Query: 193 TNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSL 372
T + ++ L+ GKG F K +++ A+ + YA E + ++
Sbjct: 146 TMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNS 205
Query: 373 QHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLH 552
+H + F+ + ++E + R + +E RFY +I+ + YLH
Sbjct: 206 RHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLH 265
Query: 553 S-KRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEIL 717
S K +++RDLKL NL LD D H+KI DFGL +G +T CGTP Y+APE+L
Sbjct: 266 SEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVL 321
>AB019245-1|BAA37145.1| 481|Homo sapiens S6 kinase b protein.
Length = 481
Score = 97.9 bits (233), Expect = 3e-20
Identities = 59/177 (33%), Positives = 91/177 (51%), Gaps = 4/177 (2%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASN--QIYAGXXXXXXXXXXXXXXEKMAQ-EISIHRSLQ 375
++ LR GKGG+ K ++++ + N +IYA + E +I S++
Sbjct: 67 FELLRVLGKGGYGKVFQVRKVQGNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILESVK 126
Query: 376 HKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETR-FYMHQILLGVQYLH 552
H +V F+ +Y+ILE C + H R+ I +T FY+ +I L + +LH
Sbjct: 127 HPFIVELAYAFQTGGKLYLILE-CLSGGELFTHLEREGIFLEDTACFYLAEITLALGHLH 185
Query: 553 SKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTK 723
S+ II+RDLK N+ L H+K+ DFGL +EG T CGT Y+APEIL +
Sbjct: 186 SQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILVR 242
>U33053-1|AAC50209.1| 942|Homo sapiens PRK1 protein.
Length = 942
Score = 97.5 bits (232), Expect = 4e-20
Identities = 57/181 (31%), Positives = 88/181 (48%), Gaps = 3/181 (1%)
Frame = +1
Query: 187 PQTNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQE---IS 357
P T ++ L G+G F K + S +++A E + E ++
Sbjct: 609 PLTLEDFKFLAVLGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVESLMCEKRILA 668
Query: 358 IHRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLG 537
S H +V F+ ++ ++E +M LH +EP FY ++LG
Sbjct: 669 AVTSAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLM-LHIHSDVFSEPRAIFYSACVVLG 727
Query: 538 VQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEIL 717
+Q+LH +I++RDLKL NL LD + +VKI DFGL G+R T CGTP ++APE+L
Sbjct: 728 LQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVL 787
Query: 718 T 720
T
Sbjct: 788 T 788
>U33052-1|AAC50208.1| 984|Homo sapiens PRK2 protein.
Length = 984
Score = 97.5 bits (232), Expect = 4e-20
Identities = 46/119 (38%), Positives = 70/119 (58%)
Frame = +1
Query: 367 SLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQY 546
S++H +V + F+ ++ ++E +M +H +EP FY ++LG+QY
Sbjct: 714 SVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLM-MHIHTDVFSEPRAVFYAACVVLGLQY 772
Query: 547 LHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTK 723
LH +I++RDLKL NL LD + VKI DFGL G+R T CGTP ++APE+LT+
Sbjct: 773 LHEHKIVYRDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTE 831
>S75548-1|AAB33346.1| 984|Homo sapiens protein kinase PRK2 protein.
Length = 984
Score = 97.5 bits (232), Expect = 4e-20
Identities = 46/119 (38%), Positives = 70/119 (58%)
Frame = +1
Query: 367 SLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQY 546
S++H +V + F+ ++ ++E +M +H +EP FY ++LG+QY
Sbjct: 714 SVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLM-MHIHTDVFSEPRAVFYAACVVLGLQY 772
Query: 547 LHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTK 723
LH +I++RDLKL NL LD + VKI DFGL G+R T CGTP ++APE+LT+
Sbjct: 773 LHEHKIVYRDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTE 831
>S75546-1|AAB33345.1| 942|Homo sapiens protein kinase PRK1 protein.
Length = 942
Score = 97.5 bits (232), Expect = 4e-20
Identities = 57/181 (31%), Positives = 88/181 (48%), Gaps = 3/181 (1%)
Frame = +1
Query: 187 PQTNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQE---IS 357
P T ++ L G+G F K + S +++A E + E ++
Sbjct: 609 PLTLEDFKFLAVLGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVESLMCEKRILA 668
Query: 358 IHRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLG 537
S H +V F+ ++ ++E +M LH +EP FY ++LG
Sbjct: 669 AVTSAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLM-LHIHSDVFSEPRAIFYSACVVLG 727
Query: 538 VQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEIL 717
+Q+LH +I++RDLKL NL LD + +VKI DFGL G+R T CGTP ++APE+L
Sbjct: 728 LQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVL 787
Query: 718 T 720
T
Sbjct: 788 T 788
>D26181-1|BAA05169.1| 942|Homo sapiens PKN protein.
Length = 942
Score = 97.5 bits (232), Expect = 4e-20
Identities = 57/181 (31%), Positives = 88/181 (48%), Gaps = 3/181 (1%)
Frame = +1
Query: 187 PQTNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQE---IS 357
P T ++ L G+G F K + S +++A E + E ++
Sbjct: 609 PLTLEDFKFLAVLGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVESLMCEKRILA 668
Query: 358 IHRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLG 537
S H +V F+ ++ ++E +M LH +EP FY ++LG
Sbjct: 669 AVTSAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLM-LHIHSDVFSEPRAIFYSACVVLG 727
Query: 538 VQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEIL 717
+Q+LH +I++RDLKL NL LD + +VKI DFGL G+R T CGTP ++APE+L
Sbjct: 728 LQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVL 787
Query: 718 T 720
T
Sbjct: 788 T 788
>BC040061-1|AAH40061.1| 942|Homo sapiens protein kinase N1 protein.
Length = 942
Score = 97.5 bits (232), Expect = 4e-20
Identities = 57/181 (31%), Positives = 88/181 (48%), Gaps = 3/181 (1%)
Frame = +1
Query: 187 PQTNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQE---IS 357
P T ++ L G+G F K + S +++A E + E ++
Sbjct: 609 PLTLEDFKFLAVLGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVESLMCEKRILA 668
Query: 358 IHRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLG 537
S H +V F+ ++ ++E +M LH +EP FY ++LG
Sbjct: 669 AVTSAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLM-LHIHSDVFSEPRAIFYSACVVLG 727
Query: 538 VQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEIL 717
+Q+LH +I++RDLKL NL LD + +VKI DFGL G+R T CGTP ++APE+L
Sbjct: 728 LQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVL 787
Query: 718 T 720
T
Sbjct: 788 T 788
>AL136381-3|CAI23271.1| 984|Homo sapiens protein kinase N2 protein.
Length = 984
Score = 97.5 bits (232), Expect = 4e-20
Identities = 46/119 (38%), Positives = 70/119 (58%)
Frame = +1
Query: 367 SLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQY 546
S++H +V + F+ ++ ++E +M +H +EP FY ++LG+QY
Sbjct: 714 SVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLM-MHIHTDVFSEPRAVFYAACVVLGLQY 772
Query: 547 LHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTK 723
LH +I++RDLKL NL LD + VKI DFGL G+R T CGTP ++APE+LT+
Sbjct: 773 LHEHKIVYRDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTE 831
>AJ271722-1|CAB71146.1| 714|Homo sapiens putative serine/threonine
protein kinase MAK-V protein.
Length = 714
Score = 97.5 bits (232), Expect = 4e-20
Identities = 52/173 (30%), Positives = 90/173 (52%), Gaps = 3/173 (1%)
Frame = +1
Query: 217 RFFGKGGFAKCYE-IQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKHVVG 393
R G+G FAK E + + ++ + + +E I + ++H ++
Sbjct: 66 RKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRHPNITQ 125
Query: 394 FHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRIIHR 573
E + Y+++ELC ++M +K + E E R Y+ Q++ V++LH ++HR
Sbjct: 126 LLDILETENSYYLVMELCPGGNLMHKIYEKKRLEESEARRYIRQLISAVEHLHRAGVVHR 185
Query: 574 DLKLGNLFLDDDLHVKIGDFGLA--ARIEYEGERKQTLCGTPNYIAPEILTKK 726
DLK+ NL LD+D ++K+ DFGL+ A I + T CG+P Y APE+L +K
Sbjct: 186 DLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLARK 238
>U08316-1|AAA81952.1| 740|Homo sapiens insulin-stimulated protein
kinase 1 protein.
Length = 740
Score = 97.1 bits (231), Expect = 6e-20
Identities = 53/187 (28%), Positives = 100/187 (53%), Gaps = 5/187 (2%)
Frame = +1
Query: 181 HDPQTNSTYQRLRFFGKGGFAKCYEIQDIASN---QIYAGXXXXXXXXXXXXXXE-KMAQ 348
H+ S ++ L+ G+G F K + ++ I+ + Q+YA KM +
Sbjct: 60 HEKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMER 119
Query: 349 EISIHRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQI 528
+I + + H +V H F+ +Y+IL+ + + + TE + +FY+ ++
Sbjct: 120 DILVE--VNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAEL 177
Query: 529 LLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAAR-IEYEGERKQTLCGTPNYIA 705
L + +LHS II+RDLK N+ LD++ H+K+ DFGL+ I++E ++ + CGT Y+A
Sbjct: 178 ALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHE-KKAYSFCGTVEYMA 236
Query: 706 PEILTKK 726
PE++ ++
Sbjct: 237 PEVVNRR 243
Score = 77.8 bits (183), Expect = 4e-14
Identities = 38/122 (31%), Positives = 70/122 (57%), Gaps = 4/122 (3%)
Frame = +1
Query: 373 QHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLH 552
QH +++ ++D +Y++ EL K +++ R+K +E E + I V+YLH
Sbjct: 472 QHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLH 531
Query: 553 SKRIIHRDLKLGN-LFLDDDLH---VKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILT 720
++ ++HRDLK N L++D+ + ++I DFG A ++ E T C T N++APE+L
Sbjct: 532 AQGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLK 591
Query: 721 KK 726
++
Sbjct: 592 RQ 593
>L07599-1|AAC82495.1| 580|Homo sapiens ribosomal protein S6 kinase
3 protein.
Length = 580
Score = 97.1 bits (231), Expect = 6e-20
Identities = 53/187 (28%), Positives = 100/187 (53%), Gaps = 5/187 (2%)
Frame = +1
Query: 181 HDPQTNSTYQRLRFFGKGGFAKCYEIQDIASN---QIYAGXXXXXXXXXXXXXXE-KMAQ 348
H+ S ++ L+ G+G F K + ++ I+ + Q+YA KM +
Sbjct: 59 HEKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMER 118
Query: 349 EISIHRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQI 528
+I + + H +V H F+ +Y+IL+ + + + TE + +FY+ ++
Sbjct: 119 DILVE--VNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAEL 176
Query: 529 LLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAAR-IEYEGERKQTLCGTPNYIA 705
L + +LHS II+RDLK N+ LD++ H+K+ DFGL+ I++E ++ + CGT Y+A
Sbjct: 177 ALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHE-KKAYSFCGTVEYMA 235
Query: 706 PEILTKK 726
PE++ ++
Sbjct: 236 PEVVNRR 242
Score = 57.6 bits (133), Expect = 4e-08
Identities = 32/110 (29%), Positives = 60/110 (54%), Gaps = 4/110 (3%)
Frame = +1
Query: 373 QHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLH 552
QH +++ + ++D +Y++ L K +++ R+K +E E + I V+YLH
Sbjct: 471 QHPNIITLNDVYDDGKYVYVVT-LMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLH 529
Query: 553 SKRIIHRDLKLGN-LFLDDDLH---VKIGDFGLAARIEYEGERKQTLCGT 690
++ ++HRDLK N L++D+ + ++I DFG A ++ E T C T
Sbjct: 530 AQGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYT 579
>BC096302-1|AAH96302.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 97.1 bits (231), Expect = 6e-20
Identities = 53/187 (28%), Positives = 100/187 (53%), Gaps = 5/187 (2%)
Frame = +1
Query: 181 HDPQTNSTYQRLRFFGKGGFAKCYEIQDIASN---QIYAGXXXXXXXXXXXXXXE-KMAQ 348
H+ S ++ L+ G+G F K + ++ I+ + Q+YA KM +
Sbjct: 60 HEKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMER 119
Query: 349 EISIHRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQI 528
+I + + H +V H F+ +Y+IL+ + + + TE + +FY+ ++
Sbjct: 120 DILVE--VNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAEL 177
Query: 529 LLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAAR-IEYEGERKQTLCGTPNYIA 705
L + +LHS II+RDLK N+ LD++ H+K+ DFGL+ I++E ++ + CGT Y+A
Sbjct: 178 ALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHE-KKAYSFCGTVEYMA 236
Query: 706 PEILTKK 726
PE++ ++
Sbjct: 237 PEVVNRR 243
Score = 77.8 bits (183), Expect = 4e-14
Identities = 38/122 (31%), Positives = 70/122 (57%), Gaps = 4/122 (3%)
Frame = +1
Query: 373 QHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLH 552
QH +++ ++D +Y++ EL K +++ R+K +E E + I V+YLH
Sbjct: 472 QHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLH 531
Query: 553 SKRIIHRDLKLGN-LFLDDDLH---VKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILT 720
++ ++HRDLK N L++D+ + ++I DFG A ++ E T C T N++APE+L
Sbjct: 532 AQGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLK 591
Query: 721 KK 726
++
Sbjct: 592 RQ 593
>BC096301-1|AAH96301.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 97.1 bits (231), Expect = 6e-20
Identities = 53/187 (28%), Positives = 100/187 (53%), Gaps = 5/187 (2%)
Frame = +1
Query: 181 HDPQTNSTYQRLRFFGKGGFAKCYEIQDIASN---QIYAGXXXXXXXXXXXXXXE-KMAQ 348
H+ S ++ L+ G+G F K + ++ I+ + Q+YA KM +
Sbjct: 60 HEKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMER 119
Query: 349 EISIHRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQI 528
+I + + H +V H F+ +Y+IL+ + + + TE + +FY+ ++
Sbjct: 120 DILVE--VNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAEL 177
Query: 529 LLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAAR-IEYEGERKQTLCGTPNYIA 705
L + +LHS II+RDLK N+ LD++ H+K+ DFGL+ I++E ++ + CGT Y+A
Sbjct: 178 ALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHE-KKAYSFCGTVEYMA 236
Query: 706 PEILTKK 726
PE++ ++
Sbjct: 237 PEVVNRR 243
Score = 77.8 bits (183), Expect = 4e-14
Identities = 38/122 (31%), Positives = 70/122 (57%), Gaps = 4/122 (3%)
Frame = +1
Query: 373 QHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLH 552
QH +++ ++D +Y++ EL K +++ R+K +E E + I V+YLH
Sbjct: 472 QHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLH 531
Query: 553 SKRIIHRDLKLGN-LFLDDDLH---VKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILT 720
++ ++HRDLK N L++D+ + ++I DFG A ++ E T C T N++APE+L
Sbjct: 532 AQGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLK 591
Query: 721 KK 726
++
Sbjct: 592 RQ 593
>AY120867-1|AAM55491.1| 752|Homo sapiens MAP/microtubule
affinity-regulating kinase-like 1 protein.
Length = 752
Score = 97.1 bits (231), Expect = 6e-20
Identities = 54/174 (31%), Positives = 81/174 (46%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKH 384
Y+ LR GKG FAK + I + + A +K+ +E+ I + L H +
Sbjct: 59 YRLLRTIGKGNFAKVKLARHILTGREVA-IKIIDKTQLNPSSLQKLFREVRIMKGLNHPN 117
Query: 385 VVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRI 564
+V E +Y+++E + + + E E R QI+ V Y H K I
Sbjct: 118 IVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNI 177
Query: 565 IHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
+HRDLK NL LD + ++KI DFG + G + T CG+P Y APE+ K
Sbjct: 178 VHRDLKAENLLLDAEANIKIADFGFSNEFTL-GSKLDTFCGSPPYAAPELFQGK 230
>AY057448-1|AAL23683.1| 752|Homo sapiens MARK4 serine/threonine
protein kinase protein.
Length = 752
Score = 97.1 bits (231), Expect = 6e-20
Identities = 54/174 (31%), Positives = 81/174 (46%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKH 384
Y+ LR GKG FAK + I + + A +K+ +E+ I + L H +
Sbjct: 59 YRLLRTIGKGNFAKVKLARHILTGREVA-IKIIDKTQLNPSSLQKLFREVRIMKGLNHPN 117
Query: 385 VVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRI 564
+V E +Y+++E + + + E E R QI+ V Y H K I
Sbjct: 118 IVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNI 177
Query: 565 IHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
+HRDLK NL LD + ++KI DFG + G + T CG+P Y APE+ K
Sbjct: 178 VHRDLKAENLLLDAEANIKIADFGFSNEFTL-GSKLDTFCGSPPYAAPELFQGK 230
>AL807772-3|CAI39687.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 97.1 bits (231), Expect = 6e-20
Identities = 53/187 (28%), Positives = 100/187 (53%), Gaps = 5/187 (2%)
Frame = +1
Query: 181 HDPQTNSTYQRLRFFGKGGFAKCYEIQDIASN---QIYAGXXXXXXXXXXXXXXE-KMAQ 348
H+ S ++ L+ G+G F K + ++ I+ + Q+YA KM +
Sbjct: 60 HEKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMER 119
Query: 349 EISIHRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQI 528
+I + + H +V H F+ +Y+IL+ + + + TE + +FY+ ++
Sbjct: 120 DILVE--VNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAEL 177
Query: 529 LLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAAR-IEYEGERKQTLCGTPNYIA 705
L + +LHS II+RDLK N+ LD++ H+K+ DFGL+ I++E ++ + CGT Y+A
Sbjct: 178 ALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHE-KKAYSFCGTVEYMA 236
Query: 706 PEILTKK 726
PE++ ++
Sbjct: 237 PEVVNRR 243
Score = 77.8 bits (183), Expect = 4e-14
Identities = 38/122 (31%), Positives = 70/122 (57%), Gaps = 4/122 (3%)
Frame = +1
Query: 373 QHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLH 552
QH +++ ++D +Y++ EL K +++ R+K +E E + I V+YLH
Sbjct: 472 QHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLH 531
Query: 553 SKRIIHRDLKLGN-LFLDDDLH---VKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILT 720
++ ++HRDLK N L++D+ + ++I DFG A ++ E T C T N++APE+L
Sbjct: 532 AQGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLK 591
Query: 721 KK 726
++
Sbjct: 592 RQ 593
>AL807772-1|CAI39684.1| 227|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 227
Score = 97.1 bits (231), Expect = 6e-20
Identities = 53/187 (28%), Positives = 100/187 (53%), Gaps = 5/187 (2%)
Frame = +1
Query: 181 HDPQTNSTYQRLRFFGKGGFAKCYEIQDIASN---QIYAGXXXXXXXXXXXXXXE-KMAQ 348
H+ S ++ L+ G+G F K + ++ I+ + Q+YA KM +
Sbjct: 31 HEKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMER 90
Query: 349 EISIHRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQI 528
+I + + H +V H F+ +Y+IL+ + + + TE + +FY+ ++
Sbjct: 91 DILVE--VNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAEL 148
Query: 529 LLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAAR-IEYEGERKQTLCGTPNYIA 705
L + +LHS II+RDLK N+ LD++ H+K+ DFGL+ I++E ++ + CGT Y+A
Sbjct: 149 ALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHE-KKAYSFCGTVEYMA 207
Query: 706 PEILTKK 726
PE++ ++
Sbjct: 208 PEVVNRR 214
>AL732366-2|CAI40548.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 97.1 bits (231), Expect = 6e-20
Identities = 53/187 (28%), Positives = 100/187 (53%), Gaps = 5/187 (2%)
Frame = +1
Query: 181 HDPQTNSTYQRLRFFGKGGFAKCYEIQDIASN---QIYAGXXXXXXXXXXXXXXE-KMAQ 348
H+ S ++ L+ G+G F K + ++ I+ + Q+YA KM +
Sbjct: 60 HEKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMER 119
Query: 349 EISIHRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQI 528
+I + + H +V H F+ +Y+IL+ + + + TE + +FY+ ++
Sbjct: 120 DILVE--VNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAEL 177
Query: 529 LLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAAR-IEYEGERKQTLCGTPNYIA 705
L + +LHS II+RDLK N+ LD++ H+K+ DFGL+ I++E ++ + CGT Y+A
Sbjct: 178 ALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHE-KKAYSFCGTVEYMA 236
Query: 706 PEILTKK 726
PE++ ++
Sbjct: 237 PEVVNRR 243
Score = 77.8 bits (183), Expect = 4e-14
Identities = 38/122 (31%), Positives = 70/122 (57%), Gaps = 4/122 (3%)
Frame = +1
Query: 373 QHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLH 552
QH +++ ++D +Y++ EL K +++ R+K +E E + I V+YLH
Sbjct: 472 QHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLH 531
Query: 553 SKRIIHRDLKLGN-LFLDDDLH---VKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILT 720
++ ++HRDLK N L++D+ + ++I DFG A ++ E T C T N++APE+L
Sbjct: 532 AQGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLK 591
Query: 721 KK 726
++
Sbjct: 592 RQ 593
>AK075272-1|BAC11510.1| 752|Homo sapiens protein ( Homo sapiens
cDNA FLJ90791 fis, clone THYRO1001593, moderately
similar to PUTATIVE SERINE/THREONINE-PROTEIN KINASE P78
(EC 2.7.1.-). ).
Length = 752
Score = 97.1 bits (231), Expect = 6e-20
Identities = 54/174 (31%), Positives = 81/174 (46%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKH 384
Y+ LR GKG FAK + I + + A +K+ +E+ I + L H +
Sbjct: 59 YRLLRTIGKGNFAKVKLARHILTGREVA-IKIIDKTQLNPSSLQKLFREVRIMKGLNHPN 117
Query: 385 VVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRI 564
+V E +Y+++E + + + E E R QI+ V Y H K I
Sbjct: 118 IVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNI 177
Query: 565 IHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
+HRDLK NL LD + ++KI DFG + G + T CG+P Y APE+ K
Sbjct: 178 VHRDLKAENLLLDAEANIKIADFGFSNEFTL-GSKLDTFCGSPPYAAPELFQGK 230
>AB208933-1|BAD92170.1| 806|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 variant protein.
Length = 806
Score = 97.1 bits (231), Expect = 6e-20
Identities = 53/187 (28%), Positives = 100/187 (53%), Gaps = 5/187 (2%)
Frame = +1
Query: 181 HDPQTNSTYQRLRFFGKGGFAKCYEIQDIASN---QIYAGXXXXXXXXXXXXXXE-KMAQ 348
H+ S ++ L+ G+G F K + ++ I+ + Q+YA KM +
Sbjct: 127 HEKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMER 186
Query: 349 EISIHRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQI 528
+I + + H +V H F+ +Y+IL+ + + + TE + +FY+ ++
Sbjct: 187 DILVE--VNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAEL 244
Query: 529 LLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAAR-IEYEGERKQTLCGTPNYIA 705
L + +LHS II+RDLK N+ LD++ H+K+ DFGL+ I++E ++ + CGT Y+A
Sbjct: 245 ALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHE-KKAYSFCGTVEYMA 303
Query: 706 PEILTKK 726
PE++ ++
Sbjct: 304 PEVVNRR 310
Score = 77.8 bits (183), Expect = 4e-14
Identities = 38/122 (31%), Positives = 70/122 (57%), Gaps = 4/122 (3%)
Frame = +1
Query: 373 QHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLH 552
QH +++ ++D +Y++ EL K +++ R+K +E E + I V+YLH
Sbjct: 538 QHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLH 597
Query: 553 SKRIIHRDLKLGN-LFLDDDLH---VKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILT 720
++ ++HRDLK N L++D+ + ++I DFG A ++ E T C T N++APE+L
Sbjct: 598 AQGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLK 657
Query: 721 KK 726
++
Sbjct: 658 RQ 659
>AB102662-1|BAC81131.1| 726|Homo sapiens RPS6KA3 protein.
Length = 726
Score = 97.1 bits (231), Expect = 6e-20
Identities = 53/187 (28%), Positives = 100/187 (53%), Gaps = 5/187 (2%)
Frame = +1
Query: 181 HDPQTNSTYQRLRFFGKGGFAKCYEIQDIASN---QIYAGXXXXXXXXXXXXXXE-KMAQ 348
H+ S ++ L+ G+G F K + ++ I+ + Q+YA KM +
Sbjct: 46 HEKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMER 105
Query: 349 EISIHRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQI 528
+I + + H +V H F+ +Y+IL+ + + + TE + +FY+ ++
Sbjct: 106 DILVE--VNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAEL 163
Query: 529 LLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAAR-IEYEGERKQTLCGTPNYIA 705
L + +LHS II+RDLK N+ LD++ H+K+ DFGL+ I++E ++ + CGT Y+A
Sbjct: 164 ALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHE-KKAYSFCGTVEYMA 222
Query: 706 PEILTKK 726
PE++ ++
Sbjct: 223 PEVVNRR 229
Score = 77.8 bits (183), Expect = 4e-14
Identities = 38/122 (31%), Positives = 70/122 (57%), Gaps = 4/122 (3%)
Frame = +1
Query: 373 QHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLH 552
QH +++ ++D +Y++ EL K +++ R+K +E E + I V+YLH
Sbjct: 458 QHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLH 517
Query: 553 SKRIIHRDLKLGN-LFLDDDLH---VKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILT 720
++ ++HRDLK N L++D+ + ++I DFG A ++ E T C T N++APE+L
Sbjct: 518 AQGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLK 577
Query: 721 KK 726
++
Sbjct: 578 RQ 579
>AB058763-1|BAB47489.1| 689|Homo sapiens KIAA1860 protein protein.
Length = 689
Score = 97.1 bits (231), Expect = 6e-20
Identities = 54/174 (31%), Positives = 81/174 (46%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKH 384
Y+ LR GKG FAK + I + + A +K+ +E+ I + L H +
Sbjct: 60 YRLLRTIGKGNFAKVKLARHILTGREVA-IKIIDKTQLNPSSLQKLFREVRIMKGLNHPN 118
Query: 385 VVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRI 564
+V E +Y+++E + + + E E R QI+ V Y H K I
Sbjct: 119 IVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNI 178
Query: 565 IHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
+HRDLK NL LD + ++KI DFG + G + T CG+P Y APE+ K
Sbjct: 179 VHRDLKAENLLLDAEANIKIADFGFSNEFTL-GSKLDTFCGSPPYAAPELFQGK 231
>Z93016-2|CAI19815.1| 487|Homo sapiens serine/threonine kinase 4
protein.
Length = 487
Score = 96.7 bits (230), Expect = 7e-20
Identities = 51/177 (28%), Positives = 93/177 (52%), Gaps = 1/177 (0%)
Frame = +1
Query: 190 QTNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRS 369
Q + L G+G + Y+ + QI A +++ +EISI +
Sbjct: 25 QPEEVFDVLEKLGEGSYGSVYKAIHKETGQIVA-----IKQVPVESDLQEIIKEISIMQQ 79
Query: 370 LQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHK-RRKAITEPETRFYMHQILLGVQY 546
HVV ++ + + +++I++E C S+ ++ + R K +TE E + L G++Y
Sbjct: 80 CDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEY 139
Query: 547 LHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEIL 717
LH R IHRD+K GN+ L+ + H K+ DFG+A ++ ++ T+ GTP ++APE++
Sbjct: 140 LHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVI 196
>Z93016-1|CAB07508.2| 462|Homo sapiens serine/threonine kinase 4
protein.
Length = 462
Score = 96.7 bits (230), Expect = 7e-20
Identities = 51/177 (28%), Positives = 93/177 (52%), Gaps = 1/177 (0%)
Frame = +1
Query: 190 QTNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRS 369
Q + L G+G + Y+ + QI A +++ +EISI +
Sbjct: 25 QPEEVFDVLEKLGEGSYGSVYKAIHKETGQIVA-----IKQVPVESDLQEIIKEISIMQQ 79
Query: 370 LQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHK-RRKAITEPETRFYMHQILLGVQY 546
HVV ++ + + +++I++E C S+ ++ + R K +TE E + L G++Y
Sbjct: 80 CDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEY 139
Query: 547 LHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEIL 717
LH R IHRD+K GN+ L+ + H K+ DFG+A ++ ++ T+ GTP ++APE++
Sbjct: 140 LHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVI 196
>U60207-1|AAB17262.1| 487|Homo sapiens serine/threonine protein
kinase Krs-2 protein.
Length = 487
Score = 96.7 bits (230), Expect = 7e-20
Identities = 51/177 (28%), Positives = 93/177 (52%), Gaps = 1/177 (0%)
Frame = +1
Query: 190 QTNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRS 369
Q + L G+G + Y+ + QI A +++ +EISI +
Sbjct: 25 QPEEVFDVLEKLGEGSYGSVYKAIHKETGQIVA-----IKQVPVESDLQEIIKEISIMQQ 79
Query: 370 LQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHK-RRKAITEPETRFYMHQILLGVQY 546
HVV ++ + + +++I++E C S+ ++ + R K +TE E + L G++Y
Sbjct: 80 CDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEY 139
Query: 547 LHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEIL 717
LH R IHRD+K GN+ L+ + H K+ DFG+A ++ ++ T+ GTP ++APE++
Sbjct: 140 LHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVI 196
>U18297-1|AAA83254.1| 487|Homo sapiens MST1 protein.
Length = 487
Score = 96.7 bits (230), Expect = 7e-20
Identities = 51/177 (28%), Positives = 93/177 (52%), Gaps = 1/177 (0%)
Frame = +1
Query: 190 QTNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRS 369
Q + L G+G + Y+ + QI A +++ +EISI +
Sbjct: 25 QPEEVFDVLEKLGEGSYGSVYKAIHKETGQIVA-----IKQVPVESDLQEIIKEISIMQQ 79
Query: 370 LQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHK-RRKAITEPETRFYMHQILLGVQY 546
HVV ++ + + +++I++E C S+ ++ + R K +TE E + L G++Y
Sbjct: 80 CDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEY 139
Query: 547 LHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEIL 717
LH R IHRD+K GN+ L+ + H K+ DFG+A ++ ++ T+ GTP ++APE++
Sbjct: 140 LHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVI 196
>BC125199-1|AAI25200.1| 936|Homo sapiens PKN2 protein protein.
Length = 936
Score = 96.7 bits (230), Expect = 7e-20
Identities = 46/119 (38%), Positives = 70/119 (58%)
Frame = +1
Query: 367 SLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQY 546
S++H +V + F+ ++ ++E +M +H +EP FY ++LG+QY
Sbjct: 666 SVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLM-MHIHTDVFSEPRAVFYAACVVLGLQY 724
Query: 547 LHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTK 723
LH +I++RDLKL NL LD + VKI DFGL G+R T CGTP ++APE+LT+
Sbjct: 725 LHEHKIVYRDLKLDNLLLDTEGLVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTE 783
>BC093768-1|AAH93768.1| 487|Homo sapiens serine/threonine kinase 4
protein.
Length = 487
Score = 96.7 bits (230), Expect = 7e-20
Identities = 51/177 (28%), Positives = 93/177 (52%), Gaps = 1/177 (0%)
Frame = +1
Query: 190 QTNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRS 369
Q + L G+G + Y+ + QI A +++ +EISI +
Sbjct: 25 QPEEVFDVLEKLGEGSYGSVYKAIHKETGQIVA-----IKQVPVESDLQEIIKEISIMQQ 79
Query: 370 LQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHK-RRKAITEPETRFYMHQILLGVQY 546
HVV ++ + + +++I++E C S+ ++ + R K +TE E + L G++Y
Sbjct: 80 CDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEY 139
Query: 547 LHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEIL 717
LH R IHRD+K GN+ L+ + H K+ DFG+A ++ ++ T+ GTP ++APE++
Sbjct: 140 LHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVI 196
>BC058916-1|AAH58916.1| 405|Homo sapiens STK4 protein protein.
Length = 405
Score = 96.7 bits (230), Expect = 7e-20
Identities = 51/177 (28%), Positives = 93/177 (52%), Gaps = 1/177 (0%)
Frame = +1
Query: 190 QTNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRS 369
Q + L G+G + Y+ + QI A +++ +EISI +
Sbjct: 25 QPEEVFDVLEKLGEGSYGSVYKAIHKETGQIVA-----IKQVPVESDLQEIIKEISIMQQ 79
Query: 370 LQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHK-RRKAITEPETRFYMHQILLGVQY 546
HVV ++ + + +++I++E C S+ ++ + R K +TE E + L G++Y
Sbjct: 80 CDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEY 139
Query: 547 LHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEIL 717
LH R IHRD+K GN+ L+ + H K+ DFG+A ++ ++ T+ GTP ++APE++
Sbjct: 140 LHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVI 196
>BC015332-1|AAH15332.1| 405|Homo sapiens Unknown (protein for
IMAGE:4400771) protein.
Length = 405
Score = 96.7 bits (230), Expect = 7e-20
Identities = 51/177 (28%), Positives = 93/177 (52%), Gaps = 1/177 (0%)
Frame = +1
Query: 190 QTNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRS 369
Q + L G+G + Y+ + QI A +++ +EISI +
Sbjct: 25 QPEEVFDVLEKLGEGSYGSVYKAIHKETGQIVA-----IKQVPVESDLQEIIKEISIMQQ 79
Query: 370 LQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHK-RRKAITEPETRFYMHQILLGVQY 546
HVV ++ + + +++I++E C S+ ++ + R K +TE E + L G++Y
Sbjct: 80 CDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEY 139
Query: 547 LHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEIL 717
LH R IHRD+K GN+ L+ + H K+ DFG+A ++ ++ T+ GTP ++APE++
Sbjct: 140 LHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVI 196
>AY702977-1|AAU29340.1| 643|Homo sapiens protein kinase C theta
protein.
Length = 643
Score = 96.7 bits (230), Expect = 7e-20
Identities = 51/171 (29%), Positives = 83/171 (48%), Gaps = 1/171 (0%)
Frame = +1
Query: 217 RFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXE-KMAQEISIHRSLQHKHVVG 393
+ GKG F K + + +NQ +A E M ++ + + +H +
Sbjct: 384 KMLGKGSFGKVFLAEFKKTNQFFAIKALKKDVVLMDDDVECTMVEKRVLSLAWEHPFLTH 443
Query: 394 FHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRIIHR 573
F+ N++ ++E +M + FY +I+LG+Q+LHSK I++R
Sbjct: 444 MFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFLHSKGIVYR 503
Query: 574 DLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
DLKL N+ LD D H+KI DFG+ + T CGTP+YIAPE+ ++
Sbjct: 504 DLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPELFVRE 554
>AL109839-4|CAI95634.1| 487|Homo sapiens serine/threonine kinase 4
protein.
Length = 487
Score = 96.7 bits (230), Expect = 7e-20
Identities = 51/177 (28%), Positives = 93/177 (52%), Gaps = 1/177 (0%)
Frame = +1
Query: 190 QTNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRS 369
Q + L G+G + Y+ + QI A +++ +EISI +
Sbjct: 25 QPEEVFDVLEKLGEGSYGSVYKAIHKETGQIVA-----IKQVPVESDLQEIIKEISIMQQ 79
Query: 370 LQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHK-RRKAITEPETRFYMHQILLGVQY 546
HVV ++ + + +++I++E C S+ ++ + R K +TE E + L G++Y
Sbjct: 80 CDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEY 139
Query: 547 LHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEIL 717
LH R IHRD+K GN+ L+ + H K+ DFG+A ++ ++ T+ GTP ++APE++
Sbjct: 140 LHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVI 196
>AL109839-3|CAI95633.1| 462|Homo sapiens serine/threonine kinase 4
protein.
Length = 462
Score = 96.7 bits (230), Expect = 7e-20
Identities = 51/177 (28%), Positives = 93/177 (52%), Gaps = 1/177 (0%)
Frame = +1
Query: 190 QTNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRS 369
Q + L G+G + Y+ + QI A +++ +EISI +
Sbjct: 25 QPEEVFDVLEKLGEGSYGSVYKAIHKETGQIVA-----IKQVPVESDLQEIIKEISIMQQ 79
Query: 370 LQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHK-RRKAITEPETRFYMHQILLGVQY 546
HVV ++ + + +++I++E C S+ ++ + R K +TE E + L G++Y
Sbjct: 80 CDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEY 139
Query: 547 LHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEIL 717
LH R IHRD+K GN+ L+ + H K+ DFG+A ++ ++ T+ GTP ++APE++
Sbjct: 140 LHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVI 196
>AB209315-1|BAD92552.1| 511|Homo sapiens serine/threonine kinase 4
variant protein.
Length = 511
Score = 96.7 bits (230), Expect = 7e-20
Identities = 51/177 (28%), Positives = 93/177 (52%), Gaps = 1/177 (0%)
Frame = +1
Query: 190 QTNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRS 369
Q + L G+G + Y+ + QI A +++ +EISI +
Sbjct: 49 QPEEVFDVLEKLGEGSYGSVYKAIHKETGQIVA-----IKQVPVESDLQEIIKEISIMQQ 103
Query: 370 LQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHK-RRKAITEPETRFYMHQILLGVQY 546
HVV ++ + + +++I++E C S+ ++ + R K +TE E + L G++Y
Sbjct: 104 CDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEY 163
Query: 547 LHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEIL 717
LH R IHRD+K GN+ L+ + H K+ DFG+A ++ ++ T+ GTP ++APE++
Sbjct: 164 LHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVI 220
>Y15056-1|CAA75341.1| 556|Homo sapiens PkB kinase protein.
Length = 556
Score = 96.3 bits (229), Expect = 1e-19
Identities = 51/172 (29%), Positives = 89/172 (51%), Gaps = 2/172 (1%)
Frame = +1
Query: 217 RFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKHVVGF 396
+ G+G F+ +++A+++ YA + +E + L H V
Sbjct: 86 KILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKL 145
Query: 397 HSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRIIHRD 576
+ F+D +Y L K +++ ++ + E TRFY +I+ ++YLH K IIHRD
Sbjct: 146 YFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRD 205
Query: 577 LKLGNLFLDDDLHVKIGDFGLAARIEYEGE--RKQTLCGTPNYIAPEILTKK 726
LK N+ L++D+H++I DFG A + E + R + GT Y++PE+LT+K
Sbjct: 206 LKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEK 257
>CR536517-1|CAG38755.1| 556|Homo sapiens PDPK1 protein.
Length = 556
Score = 96.3 bits (229), Expect = 1e-19
Identities = 51/172 (29%), Positives = 89/172 (51%), Gaps = 2/172 (1%)
Frame = +1
Query: 217 RFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKHVVGF 396
+ G+G F+ +++A+++ YA + +E + L H V
Sbjct: 86 KILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKL 145
Query: 397 HSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRIIHRD 576
+ F+D +Y L K +++ ++ + E TRFY +I+ ++YLH K IIHRD
Sbjct: 146 YFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRD 205
Query: 577 LKLGNLFLDDDLHVKIGDFGLAARIEYEGE--RKQTLCGTPNYIAPEILTKK 726
LK N+ L++D+H++I DFG A + E + R + GT Y++PE+LT+K
Sbjct: 206 LKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEK 257
>BC117183-1|AAI17184.1| 926|Homo sapiens SNF1-like kinase 2
protein.
Length = 926
Score = 96.3 bits (229), Expect = 1e-19
Identities = 45/127 (35%), Positives = 69/127 (54%)
Frame = +1
Query: 334 EKMAQEISIHRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRF 513
EK+ +E+ I + L H H++ + E +Y++ E K + + + E E R
Sbjct: 62 EKIYREVQIMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARR 121
Query: 514 YMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTP 693
QIL V Y H ++I+HRDLK NL LD+++++KI DFG + GE T CG+P
Sbjct: 122 KFWQILSAVDYCHGRKIVHRDLKAENLLLDNNMNIKIADFGFGNFFK-SGELLATWCGSP 180
Query: 694 NYIAPEI 714
Y APE+
Sbjct: 181 PYAAPEV 187
>BC114478-1|AAI14479.1| 795|Homo sapiens MARK1 protein protein.
Length = 795
Score = 96.3 bits (229), Expect = 1e-19
Identities = 53/174 (30%), Positives = 82/174 (47%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKH 384
Y+ + GKG FAK + + + + A +K+ +E+ I + L H +
Sbjct: 60 YRLQKTIGKGNFAKVKLARHVLTGREVA-VKIIDKTQLNPTSLQKLFREVRIMKILNHPN 118
Query: 385 VVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRI 564
+V E +Y+++E + + + E E R QI+ VQY H K I
Sbjct: 119 IVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYI 178
Query: 565 IHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
+HRDLK NL LD D+++KI DFG + G + T CG+P Y APE+ K
Sbjct: 179 VHRDLKAENLLLDGDMNIKIADFGFSNEFTV-GNKLDTFCGSPPYAAPELFQGK 231
>BC113869-1|AAI13870.1| 795|Homo sapiens MARK1 protein protein.
Length = 795
Score = 96.3 bits (229), Expect = 1e-19
Identities = 53/174 (30%), Positives = 82/174 (47%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKH 384
Y+ + GKG FAK + + + + A +K+ +E+ I + L H +
Sbjct: 60 YRLQKTIGKGNFAKVKLARHVLTGREVA-VKIIDKTQLNPTSLQKLFREVRIMKILNHPN 118
Query: 385 VVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRI 564
+V E +Y+++E + + + E E R QI+ VQY H K I
Sbjct: 119 IVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYI 178
Query: 565 IHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
+HRDLK NL LD D+++KI DFG + G + T CG+P Y APE+ K
Sbjct: 179 VHRDLKAENLLLDGDMNIKIADFGFSNEFTV-GNKLDTFCGSPPYAAPELFQGK 231
>BC113459-1|AAI13460.1| 926|Homo sapiens SNF1-like kinase 2
protein.
Length = 926
Score = 96.3 bits (229), Expect = 1e-19
Identities = 45/127 (35%), Positives = 69/127 (54%)
Frame = +1
Query: 334 EKMAQEISIHRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRF 513
EK+ +E+ I + L H H++ + E +Y++ E K + + + E E R
Sbjct: 62 EKIYREVQIMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARR 121
Query: 514 YMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTP 693
QIL V Y H ++I+HRDLK NL LD+++++KI DFG + GE T CG+P
Sbjct: 122 KFWQILSAVDYCHGRKIVHRDLKAENLLLDNNMNIKIADFGFGNFFK-SGELLATWCGSP 180
Query: 694 NYIAPEI 714
Y APE+
Sbjct: 181 PYAAPEV 187
>BC096303-1|AAH96303.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 96.3 bits (229), Expect = 1e-19
Identities = 53/187 (28%), Positives = 99/187 (52%), Gaps = 5/187 (2%)
Frame = +1
Query: 181 HDPQTNSTYQRLRFFGKGGFAKCYEIQDIASN---QIYAGXXXXXXXXXXXXXXE-KMAQ 348
H+ S ++ L+ G+G F K + ++ I + Q+YA KM +
Sbjct: 60 HEKADPSQFELLKVLGQGSFGKVFLVKKILGSDARQLYAMKVLKKATLKVRDRVRTKMER 119
Query: 349 EISIHRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQI 528
+I + + H +V H F+ +Y+IL+ + + + TE + +FY+ ++
Sbjct: 120 DILVE--VNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAEL 177
Query: 529 LLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAAR-IEYEGERKQTLCGTPNYIA 705
L + +LHS II+RDLK N+ LD++ H+K+ DFGL+ I++E ++ + CGT Y+A
Sbjct: 178 ALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHE-KKAYSFCGTVEYMA 236
Query: 706 PEILTKK 726
PE++ ++
Sbjct: 237 PEVVNRR 243
Score = 77.8 bits (183), Expect = 4e-14
Identities = 38/122 (31%), Positives = 70/122 (57%), Gaps = 4/122 (3%)
Frame = +1
Query: 373 QHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLH 552
QH +++ ++D +Y++ EL K +++ R+K +E E + I V+YLH
Sbjct: 472 QHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLH 531
Query: 553 SKRIIHRDLKLGN-LFLDDDLH---VKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILT 720
++ ++HRDLK N L++D+ + ++I DFG A ++ E T C T N++APE+L
Sbjct: 532 AQGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLK 591
Query: 721 KK 726
++
Sbjct: 592 RQ 593
>BC062558-1|AAH62558.1| 889|Homo sapiens protein kinase N3 protein.
Length = 889
Score = 96.3 bits (229), Expect = 1e-19
Identities = 59/184 (32%), Positives = 92/184 (50%), Gaps = 4/184 (2%)
Frame = +1
Query: 187 PQTNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHR 366
P ++ L G+G F K +Q + + YA E + E I
Sbjct: 553 PPRLQDFRCLAVLGRGHFGKVLLVQFKGTGKYYAIKALKKQEVLSRDEIESLYCEKRILE 612
Query: 367 SLQ---HKHVVGFHSFFEDSLNIYIILELCKKRS-MMELHKRRKAITEPETRFYMHQILL 534
++ H ++ + F+ S + + E MM++H+ EP+ RFY+ ++L
Sbjct: 613 AVGCTGHPFLLSLLACFQTSSHACFVTEFVPGGDLMMQIHE--DVFPEPQARFYVACVVL 670
Query: 535 GVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEI 714
G+Q+LH K+II+RDLKL NL LD +KI DFGL G+R T CGTP ++APE+
Sbjct: 671 GLQFLHEKKIIYRDLKLDNLLLDAQGFLKIADFGLCKEGIGFGDRTSTFCGTPEFLAPEV 730
Query: 715 LTKK 726
LT++
Sbjct: 731 LTQE 734
>BC012103-1|AAH12103.1| 556|Homo sapiens 3-phosphoinositide
dependent protein kinase-1 protein.
Length = 556
Score = 96.3 bits (229), Expect = 1e-19
Identities = 51/172 (29%), Positives = 89/172 (51%), Gaps = 2/172 (1%)
Frame = +1
Query: 217 RFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKHVVGF 396
+ G+G F+ +++A+++ YA + +E + L H V
Sbjct: 86 KILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKL 145
Query: 397 HSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRIIHRD 576
+ F+D +Y L K +++ ++ + E TRFY +I+ ++YLH K IIHRD
Sbjct: 146 YFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRD 205
Query: 577 LKLGNLFLDDDLHVKIGDFGLAARIEYEGE--RKQTLCGTPNYIAPEILTKK 726
LK N+ L++D+H++I DFG A + E + R + GT Y++PE+LT+K
Sbjct: 206 LKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEK 257
>AL592406-3|CAH72463.1| 795|Homo sapiens MAP/microtubule
affinity-regulating kinase 1 protein.
Length = 795
Score = 96.3 bits (229), Expect = 1e-19
Identities = 53/174 (30%), Positives = 82/174 (47%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKH 384
Y+ + GKG FAK + + + + A +K+ +E+ I + L H +
Sbjct: 60 YRLQKTIGKGNFAKVKLARHVLTGREVA-VKIIDKTQLNPTSLQKLFREVRIMKILNHPN 118
Query: 385 VVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRI 564
+V E +Y+++E + + + E E R QI+ VQY H K I
Sbjct: 119 IVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYI 178
Query: 565 IHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
+HRDLK NL LD D+++KI DFG + G + T CG+P Y APE+ K
Sbjct: 179 VHRDLKAENLLLDGDMNIKIADFGFSNEFTV-GNKLDTFCGSPPYAAPELFQGK 231
>AL441992-1|CAI15401.1| 889|Homo sapiens protein kinase N3 protein.
Length = 889
Score = 96.3 bits (229), Expect = 1e-19
Identities = 59/184 (32%), Positives = 92/184 (50%), Gaps = 4/184 (2%)
Frame = +1
Query: 187 PQTNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHR 366
P ++ L G+G F K +Q + + YA E + E I
Sbjct: 553 PPRLQDFRCLAVLGRGHFGKVLLVQFKGTGKYYAIKALKKQEVLSRDEIESLYCEKRILE 612
Query: 367 SLQ---HKHVVGFHSFFEDSLNIYIILELCKKRS-MMELHKRRKAITEPETRFYMHQILL 534
++ H ++ + F+ S + + E MM++H+ EP+ RFY+ ++L
Sbjct: 613 AVGCTGHPFLLSLLACFQTSSHACFVTEFVPGGDLMMQIHE--DVFPEPQARFYVACVVL 670
Query: 535 GVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEI 714
G+Q+LH K+II+RDLKL NL LD +KI DFGL G+R T CGTP ++APE+
Sbjct: 671 GLQFLHEKKIIYRDLKLDNLLLDAQGFLKIADFGLCKEGIGFGDRTSTFCGTPEFLAPEV 730
Query: 715 LTKK 726
LT++
Sbjct: 731 LTQE 734
>AF154845-1|AAF72103.1| 795|Homo sapiens MARK protein.
Length = 795
Score = 96.3 bits (229), Expect = 1e-19
Identities = 53/174 (30%), Positives = 82/174 (47%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKH 384
Y+ + GKG FAK + + + + A +K+ +E+ I + L H +
Sbjct: 60 YRLQKTIGKGNFAKVKLARHVLTGREVA-VKIIDKTQLNPTSLQKLFREVRIMKILNHPN 118
Query: 385 VVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRI 564
+V E +Y+++E + + + E E R QI+ VQY H K I
Sbjct: 119 IVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYI 178
Query: 565 IHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
+HRDLK NL LD D+++KI DFG + G + T CG+P Y APE+ K
Sbjct: 179 VHRDLKAENLLLDGDMNIKIADFGFSNEFTV-GNKLDTFCGSPPYAAPELFQGK 231
>AF017995-1|AAC51825.1| 556|Homo sapiens 3-phosphoinositide
dependent protein kinase-1 protein.
Length = 556
Score = 96.3 bits (229), Expect = 1e-19
Identities = 51/172 (29%), Positives = 89/172 (51%), Gaps = 2/172 (1%)
Frame = +1
Query: 217 RFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKHVVGF 396
+ G+G F+ +++A+++ YA + +E + L H V
Sbjct: 86 KILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKL 145
Query: 397 HSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRIIHRD 576
+ F+D +Y L K +++ ++ + E TRFY +I+ ++YLH K IIHRD
Sbjct: 146 YFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRD 205
Query: 577 LKLGNLFLDDDLHVKIGDFGLAARIEYEGE--RKQTLCGTPNYIAPEILTKK 726
LK N+ L++D+H++I DFG A + E + R + GT Y++PE+LT+K
Sbjct: 206 LKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEK 257
>AC005591-1|AAC33797.1| 367|Homo sapiens PkB-like protein.
Length = 367
Score = 96.3 bits (229), Expect = 1e-19
Identities = 51/172 (29%), Positives = 89/172 (51%), Gaps = 2/172 (1%)
Frame = +1
Query: 217 RFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKHVVGF 396
+ G+G F+ +++A+++ YA + +E + L H V
Sbjct: 78 KILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKL 137
Query: 397 HSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRIIHRD 576
+ F+D +Y L K +++ ++ + E TRFY +I+ ++YLH K IIHRD
Sbjct: 138 YFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRD 197
Query: 577 LKLGNLFLDDDLHVKIGDFGLAARIEYEGE--RKQTLCGTPNYIAPEILTKK 726
LK N+ L++D+H++I DFG A + E + R + GT Y++PE+LT+K
Sbjct: 198 LKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEK 249
>AB209835-1|BAD93072.1| 492|Homo sapiens 3-phosphoinositide
dependent protein kinase-1 variant protein.
Length = 492
Score = 96.3 bits (229), Expect = 1e-19
Identities = 51/172 (29%), Positives = 89/172 (51%), Gaps = 2/172 (1%)
Frame = +1
Query: 217 RFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKHVVGF 396
+ G+G F+ +++A+++ YA + +E + L H V
Sbjct: 124 KILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKL 183
Query: 397 HSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRIIHRD 576
+ F+D +Y L K +++ ++ + E TRFY +I+ ++YLH K IIHRD
Sbjct: 184 YFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRD 243
Query: 577 LKLGNLFLDDDLHVKIGDFGLAARIEYEGE--RKQTLCGTPNYIAPEILTKK 726
LK N+ L++D+H++I DFG A + E + R + GT Y++PE+LT+K
Sbjct: 244 LKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEK 295
>AB084424-1|BAB91442.1| 346|Homo sapiens KIAA0781 protein protein.
Length = 346
Score = 96.3 bits (229), Expect = 1e-19
Identities = 45/127 (35%), Positives = 69/127 (54%)
Frame = +1
Query: 334 EKMAQEISIHRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRF 513
EK+ +E+ I + L H H++ + E +Y++ E K + + + E E R
Sbjct: 60 EKIYREVQIMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARR 119
Query: 514 YMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTP 693
QIL V Y H ++I+HRDLK NL LD+++++KI DFG + GE T CG+P
Sbjct: 120 KFWQILSAVDYCHGRKIVHRDLKAENLLLDNNMNIKIADFGFGNFFK-SGELLATWCGSP 178
Query: 694 NYIAPEI 714
Y APE+
Sbjct: 179 PYAAPEV 185
>AB018324-1|BAA34501.3| 950|Homo sapiens KIAA0781 protein protein.
Length = 950
Score = 96.3 bits (229), Expect = 1e-19
Identities = 45/127 (35%), Positives = 69/127 (54%)
Frame = +1
Query: 334 EKMAQEISIHRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRF 513
EK+ +E+ I + L H H++ + E +Y++ E K + + + E E R
Sbjct: 86 EKIYREVQIMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARR 145
Query: 514 YMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTP 693
QIL V Y H ++I+HRDLK NL LD+++++KI DFG + GE T CG+P
Sbjct: 146 KFWQILSAVDYCHGRKIVHRDLKAENLLLDNNMNIKIADFGFGNFFK-SGELLATWCGSP 204
Query: 694 NYIAPEI 714
Y APE+
Sbjct: 205 PYAAPEV 211
>X80229-1|CAA56515.1| 479|Homo sapiens serine/threonine protein
kinase protein.
Length = 479
Score = 95.9 bits (228), Expect = 1e-19
Identities = 56/181 (30%), Positives = 88/181 (48%), Gaps = 3/181 (1%)
Frame = +1
Query: 187 PQTNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQE---IS 357
P T ++ L G+G F K + S +++A E + E ++
Sbjct: 146 PLTLEDFKFLAVLGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVESLMCEKRILA 205
Query: 358 IHRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLG 537
S H +V F+ ++ ++E ++ LH +EP FY ++LG
Sbjct: 206 AVTSAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLI-LHIHSDVFSEPRAIFYSACVVLG 264
Query: 538 VQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEIL 717
+Q+LH +I++RDLKL NL LD + +VKI DFGL G+R T CGTP ++APE+L
Sbjct: 265 LQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVL 324
Query: 718 T 720
T
Sbjct: 325 T 325
>BC114506-1|AAI14507.1| 370|Homo sapiens death-associated protein
kinase 2 protein.
Length = 370
Score = 95.9 bits (228), Expect = 1e-19
Identities = 49/132 (37%), Positives = 84/132 (63%), Gaps = 4/132 (3%)
Frame = +1
Query: 334 EKMAQEISIHRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRF 513
E++ +E+SI R + H +V+ H +E+ ++ +ILEL + + ++++++E E
Sbjct: 69 EEIEREVSILRQVLHHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATS 128
Query: 514 YMHQILLGVQYLHSKRIIHRDLKLGN-LFLDDDL---HVKIGDFGLAARIEYEGERKQTL 681
++ QIL GV YLH+K+I H DLK N + LD ++ H+K+ DFGLA IE +G + +
Sbjct: 129 FIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIE-DGVEFKNI 187
Query: 682 CGTPNYIAPEIL 717
GTP ++APEI+
Sbjct: 188 FGTPEFVAPEIV 199
>AF052941-1|AAC35001.1| 370|Homo sapiens DAP-kinase related protein
1 protein.
Length = 370
Score = 95.9 bits (228), Expect = 1e-19
Identities = 49/132 (37%), Positives = 84/132 (63%), Gaps = 4/132 (3%)
Frame = +1
Query: 334 EKMAQEISIHRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRF 513
E++ +E+SI R + H +V+ H +E+ ++ +ILEL + + ++++++E E
Sbjct: 69 EEIEREVSILRQVLHHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATS 128
Query: 514 YMHQILLGVQYLHSKRIIHRDLKLGN-LFLDDDL---HVKIGDFGLAARIEYEGERKQTL 681
++ QIL GV YLH+K+I H DLK N + LD ++ H+K+ DFGLA IE +G + +
Sbjct: 129 FIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIE-DGVEFKNI 187
Query: 682 CGTPNYIAPEIL 717
GTP ++APEI+
Sbjct: 188 FGTPEFVAPEIV 199
>AB018001-1|BAA88063.1| 370|Homo sapiens Death-associated protein
kinase 2 protein.
Length = 370
Score = 95.9 bits (228), Expect = 1e-19
Identities = 49/132 (37%), Positives = 84/132 (63%), Gaps = 4/132 (3%)
Frame = +1
Query: 334 EKMAQEISIHRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRF 513
E++ +E+SI R + H +V+ H +E+ ++ +ILEL + + ++++++E E
Sbjct: 69 EEIEREVSILRQVLHHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATS 128
Query: 514 YMHQILLGVQYLHSKRIIHRDLKLGN-LFLDDDL---HVKIGDFGLAARIEYEGERKQTL 681
++ QIL GV YLH+K+I H DLK N + LD ++ H+K+ DFGLA IE +G + +
Sbjct: 129 FIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIE-DGVEFKNI 187
Query: 682 CGTPNYIAPEIL 717
GTP ++APEI+
Sbjct: 188 FGTPEFVAPEIV 199
>BC029511-1|AAH29511.1| 405|Homo sapiens STK4 protein protein.
Length = 405
Score = 95.5 bits (227), Expect = 2e-19
Identities = 51/177 (28%), Positives = 92/177 (51%), Gaps = 1/177 (0%)
Frame = +1
Query: 190 QTNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRS 369
Q + L G+G + Y+ + QI A +++ +EISI +
Sbjct: 25 QPEEVFDVLEKLGEGSYGSVYKAIHKETGQIVA-----IKQVPVESDLQEIIKEISIMQQ 79
Query: 370 LQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHK-RRKAITEPETRFYMHQILLGVQY 546
HVV ++ + + +++I++E C S+ ++ + R K +TE E + L G++Y
Sbjct: 80 CDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEY 139
Query: 547 LHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEIL 717
LH R IHRD+K GN+ L+ + H K+ DFG+A ++ ++ T+ GTP +APE++
Sbjct: 140 LHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFLMAPEVI 196
>BC022515-1|AAH22515.1| 367|Homo sapiens testis-specific serine
kinase 1B protein.
Length = 367
Score = 95.5 bits (227), Expect = 2e-19
Identities = 49/131 (37%), Positives = 75/131 (57%), Gaps = 5/131 (3%)
Frame = +1
Query: 340 MAQEISIHRSLQHKHVVGFHSFFEDSLN-IYIILELCKKRSMMELHKRRKAITEPETRFY 516
+ +EI I L H ++ + FE S +YI++EL + ++EL K R A+ E E R
Sbjct: 57 LPREIEILAMLNHCSIIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGALHEDEARKK 116
Query: 517 MHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAAR-IEYEGER---KQTLC 684
HQ+ L ++Y H ++HRDLK NL LD D ++K+ DF + R + + R +T C
Sbjct: 117 FHQLSLAIKYCHDLDVVHRDLKCDNLLLDKDFNIKLSDFSFSKRCLRDDSGRMALSKTFC 176
Query: 685 GTPNYIAPEIL 717
G+P Y APE+L
Sbjct: 177 GSPAYAAPEVL 187
>AY028964-1|AAK27734.1| 367|Homo sapiens testis-specific
serine/threonine kinase 1 protein.
Length = 367
Score = 95.5 bits (227), Expect = 2e-19
Identities = 49/131 (37%), Positives = 75/131 (57%), Gaps = 5/131 (3%)
Frame = +1
Query: 340 MAQEISIHRSLQHKHVVGFHSFFEDSLN-IYIILELCKKRSMMELHKRRKAITEPETRFY 516
+ +EI I L H ++ + FE S +YI++EL + ++EL K R A+ E E R
Sbjct: 57 LPREIEILAMLNHCSIIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGALHEDEARKK 116
Query: 517 MHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAAR-IEYEGER---KQTLC 684
HQ+ L ++Y H ++HRDLK NL LD D ++K+ DF + R + + R +T C
Sbjct: 117 FHQLSLAIKYCHDLDVVHRDLKCDNLLLDKDFNIKLSDFSFSKRCLRDDSGRMALSKTFC 176
Query: 685 GTPNYIAPEIL 717
G+P Y APE+L
Sbjct: 177 GSPAYAAPEVL 187
>AB284522-1|BAF41973.1| 367|Homo sapiens testis-specific serine
kinase 1 protein.
Length = 367
Score = 95.5 bits (227), Expect = 2e-19
Identities = 49/131 (37%), Positives = 75/131 (57%), Gaps = 5/131 (3%)
Frame = +1
Query: 340 MAQEISIHRSLQHKHVVGFHSFFEDSLN-IYIILELCKKRSMMELHKRRKAITEPETRFY 516
+ +EI I L H ++ + FE S +YI++EL + ++EL K R A+ E E R
Sbjct: 57 LPREIEILAMLNHCSIIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGALHEDEARKK 116
Query: 517 MHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAAR-IEYEGER---KQTLC 684
HQ+ L ++Y H ++HRDLK NL LD D ++K+ DF + R + + R +T C
Sbjct: 117 FHQLSLAIKYCHDLDVVHRDLKCDNLLLDKDFNIKLSDFSFSKRCLRDDSGRMALSKTFC 176
Query: 685 GTPNYIAPEIL 717
G+P Y APE+L
Sbjct: 177 GSPAYAAPEVL 187
>Z98752-7|CAI42315.1| 366|Homo sapiens serum/glucocorticoid
regulated kinase 2 protein.
Length = 366
Score = 95.1 bits (226), Expect = 2e-19
Identities = 53/182 (29%), Positives = 83/182 (45%), Gaps = 1/182 (0%)
Frame = +1
Query: 184 DPQTNST-YQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISI 360
+P T + L+ GKG + K + + YA MA+ +
Sbjct: 27 NPNAQPTDFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKESHIMAERSVL 86
Query: 361 HRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGV 540
++++H +VG F+ +Y +L+ + +R + EP RFY ++ +
Sbjct: 87 LKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAI 146
Query: 541 QYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILT 720
YLHS II+RDLK N+ LD HV + DFGL + T CGTP Y+APE+L
Sbjct: 147 GYLHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLR 206
Query: 721 KK 726
K+
Sbjct: 207 KE 208
>L07597-1|AAC82497.1| 735|Homo sapiens ribosomal protein S6 kinase
1 protein.
Length = 735
Score = 95.1 bits (226), Expect = 2e-19
Identities = 50/179 (27%), Positives = 90/179 (50%), Gaps = 3/179 (1%)
Frame = +1
Query: 199 STYQRLRFFGKGGFAKCYEIQDIA---SNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRS 369
S ++ L+ G+G F K + ++ + S +YA + E I
Sbjct: 60 SHFELLKVLGQGSFGKVFLVRKVTRPDSGHLYA-MKVLKKATLKVRDRVRTKMERDILAD 118
Query: 370 LQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYL 549
+ H VV H F+ +Y+IL+ + + + TE + +FY+ ++ LG+ +L
Sbjct: 119 VNHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHL 178
Query: 550 HSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
HS II+RDLK N+ LD++ H+K+ DFGL+ ++ + CGT Y+APE++ ++
Sbjct: 179 HSLGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQ 237
Score = 83.8 bits (198), Expect = 6e-16
Identities = 44/133 (33%), Positives = 79/133 (59%), Gaps = 5/133 (3%)
Frame = +1
Query: 343 AQEISIH-RSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYM 519
++EI I R QH +++ ++D ++Y++ EL + +++ R+K +E E F +
Sbjct: 457 SEEIEILLRYGQHPNIITLKDVYDDGKHVYLVTELMRGGELLDKILRQKFFSEREASFVL 516
Query: 520 HQILLGVQYLHSKRIIHRDLKLGN-LFLDDDLH---VKIGDFGLAARIEYEGERKQTLCG 687
H I V+YLHS+ ++HRDLK N L++D+ + ++I DFG A ++ E T C
Sbjct: 517 HTIGKTVEYLHSQGVVHRDLKPSNILYVDESGNPECLRICDFGFAKQLRAENGLLMTPCY 576
Query: 688 TPNYIAPEILTKK 726
T N++APE+L ++
Sbjct: 577 TANFVAPEVLKRQ 589
>BC114491-1|AAI14492.1| 1189|Homo sapiens NEK1 protein protein.
Length = 1189
Score = 95.1 bits (226), Expect = 2e-19
Identities = 48/176 (27%), Positives = 94/176 (53%), Gaps = 2/176 (1%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKH 384
Y RL+ G+G F K ++ + Y E+ +E+++ +++H +
Sbjct: 4 YVRLQKIGEGSFGKAILVKSTEDGRQYV-IKEINISRMSSKEREESRREVAVLANMKHPN 62
Query: 385 VVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRF--YMHQILLGVQYLHSK 558
+V + FE++ ++YI+++ C+ + + +K + E + + QI L ++++H +
Sbjct: 63 IVQYRESFEENGSLYIVMDYCEGGDLFKRINAQKGVLFQEDQILDWFVQICLALKHVHDR 122
Query: 559 RIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
+I+HRD+K N+FL D V++GDFG+A + E +T GTP Y++PEI K
Sbjct: 123 KILHRDIKSQNIFLTKDGTVQLGDFGIARVLNSTVELARTCIGTPYYLSPEICENK 178
>BC017575-1|AAH17575.1| 476|Homo sapiens CHK1 checkpoint homolog
(S. pombe) protein.
Length = 476
Score = 95.1 bits (226), Expect = 2e-19
Identities = 47/133 (35%), Positives = 75/133 (56%), Gaps = 2/133 (1%)
Frame = +1
Query: 334 EKMAQEISIHRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRF 513
E + +EI I++ L H++VV F+ + Y+ LE C + + + + EP+ +
Sbjct: 50 ENIKKEICINKMLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQR 109
Query: 514 YMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERK--QTLCG 687
+ HQ++ GV YLH I HRD+K NL LD+ ++KI DFGLA Y + +CG
Sbjct: 110 FFHQLMAGVVYLHGIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCG 169
Query: 688 TPNYIAPEILTKK 726
T Y+APE+L ++
Sbjct: 170 TLPYVAPELLKRR 182
>BC015147-1|AAH15147.1| 403|Homo sapiens Unknown (protein for
IMAGE:4063881) protein.
Length = 403
Score = 95.1 bits (226), Expect = 2e-19
Identities = 48/176 (27%), Positives = 94/176 (53%), Gaps = 2/176 (1%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKH 384
Y RL+ G+G F K ++ + Y E+ +E+++ +++H +
Sbjct: 4 YVRLQKIGEGSFGKAILVKSTEDGRQYV-IKEINISRMSSKEREESRREVAVLANMKHPN 62
Query: 385 VVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRF--YMHQILLGVQYLHSK 558
+V + FE++ ++YI+++ C+ + + +K + E + + QI L ++++H +
Sbjct: 63 IVQYRESFEENGSLYIVMDYCEGGDLFKRINAQKGVLFQEDQILDWFVQICLALKHVHDR 122
Query: 559 RIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
+I+HRD+K N+FL D V++GDFG+A + E +T GTP Y++PEI K
Sbjct: 123 KILHRDIKSQNIFLTKDGTVQLGDFGIARVLNSTVELARTCIGTPYYLSPEICENK 178
>BC014966-1|AAH14966.1| 735|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 1 protein.
Length = 735
Score = 95.1 bits (226), Expect = 2e-19
Identities = 50/179 (27%), Positives = 90/179 (50%), Gaps = 3/179 (1%)
Frame = +1
Query: 199 STYQRLRFFGKGGFAKCYEIQDIA---SNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRS 369
S ++ L+ G+G F K + ++ + S +YA + E I
Sbjct: 60 SHFELLKVLGQGSFGKVFLVRKVTRPDSGHLYA-MKVLKKATLKVRDRVRTKMERDILAD 118
Query: 370 LQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYL 549
+ H VV H F+ +Y+IL+ + + + TE + +FY+ ++ LG+ +L
Sbjct: 119 VNHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHL 178
Query: 550 HSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
HS II+RDLK N+ LD++ H+K+ DFGL+ ++ + CGT Y+APE++ ++
Sbjct: 179 HSLGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQ 237
Score = 83.8 bits (198), Expect = 6e-16
Identities = 44/133 (33%), Positives = 79/133 (59%), Gaps = 5/133 (3%)
Frame = +1
Query: 343 AQEISIH-RSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYM 519
++EI I R QH +++ ++D ++Y++ EL + +++ R+K +E E F +
Sbjct: 457 SEEIEILLRYGQHPNIITLKDVYDDGKHVYLVTELMRGGELLDKILRQKFFSEREASFVL 516
Query: 520 HQILLGVQYLHSKRIIHRDLKLGN-LFLDDDLH---VKIGDFGLAARIEYEGERKQTLCG 687
H I V+YLHS+ ++HRDLK N L++D+ + ++I DFG A ++ E T C
Sbjct: 517 HTIGKTVEYLHSQGVVHRDLKPSNILYVDESGNPECLRICDFGFAKQLRAENGLLMTPCY 576
Query: 688 TPNYIAPEILTKK 726
T N++APE+L ++
Sbjct: 577 TANFVAPEVLKRQ 589
>BC006106-1|AAH06106.3| 482|Homo sapiens ribosomal protein S6
kinase, 70kDa, polypeptide 2 protein.
Length = 482
Score = 95.1 bits (226), Expect = 2e-19
Identities = 58/179 (32%), Positives = 91/179 (50%), Gaps = 5/179 (2%)
Frame = +1
Query: 202 TYQRLRFFGKGGFAKCYEIQDIASN---QIYAGXXXXXXXXXXXXXXEKMAQ-EISIHRS 369
+++ LR GKGG+ K ++++ + +IYA + E +I S
Sbjct: 66 SFELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILES 125
Query: 370 LQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETR-FYMHQILLGVQY 546
++H +V F+ +Y+ILE C + H R+ I +T FY+ +I L + +
Sbjct: 126 VKHPFIVELAYAFQTGGKLYLILE-CLSGGELFTHLEREGIFLEDTACFYLAEITLALGH 184
Query: 547 LHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTK 723
LHS+ II+RDLK N+ L H+K+ DFGL +EG T CGT Y+APEIL +
Sbjct: 185 LHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILVR 243
>BC004202-1|AAH04202.1| 476|Homo sapiens CHEK1 protein protein.
Length = 476
Score = 95.1 bits (226), Expect = 2e-19
Identities = 47/133 (35%), Positives = 75/133 (56%), Gaps = 2/133 (1%)
Frame = +1
Query: 334 EKMAQEISIHRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRF 513
E + +EI I++ L H++VV F+ + Y+ LE C + + + + EP+ +
Sbjct: 50 ENIKKEICINKMLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQR 109
Query: 514 YMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERK--QTLCG 687
+ HQ++ GV YLH I HRD+K NL LD+ ++KI DFGLA Y + +CG
Sbjct: 110 FFHQLMAGVVYLHGIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCG 169
Query: 688 TPNYIAPEILTKK 726
T Y+APE+L ++
Sbjct: 170 TLPYVAPELLKRR 182
>AL627313-6|CAI14649.1| 735|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 1 protein.
Length = 735
Score = 95.1 bits (226), Expect = 2e-19
Identities = 50/179 (27%), Positives = 90/179 (50%), Gaps = 3/179 (1%)
Frame = +1
Query: 199 STYQRLRFFGKGGFAKCYEIQDIA---SNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRS 369
S ++ L+ G+G F K + ++ + S +YA + E I
Sbjct: 60 SHFELLKVLGQGSFGKVFLVRKVTRPDSGHLYA-MKVLKKATLKVRDRVRTKMERDILAD 118
Query: 370 LQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYL 549
+ H VV H F+ +Y+IL+ + + + TE + +FY+ ++ LG+ +L
Sbjct: 119 VNHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHL 178
Query: 550 HSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
HS II+RDLK N+ LD++ H+K+ DFGL+ ++ + CGT Y+APE++ ++
Sbjct: 179 HSLGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQ 237
Score = 83.8 bits (198), Expect = 6e-16
Identities = 44/133 (33%), Positives = 79/133 (59%), Gaps = 5/133 (3%)
Frame = +1
Query: 343 AQEISIH-RSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYM 519
++EI I R QH +++ ++D ++Y++ EL + +++ R+K +E E F +
Sbjct: 457 SEEIEILLRYGQHPNIITLKDVYDDGKHVYLVTELMRGGELLDKILRQKFFSEREASFVL 516
Query: 520 HQILLGVQYLHSKRIIHRDLKLGN-LFLDDDLH---VKIGDFGLAARIEYEGERKQTLCG 687
H I V+YLHS+ ++HRDLK N L++D+ + ++I DFG A ++ E T C
Sbjct: 517 HTIGKTVEYLHSQGVVHRDLKPSNILYVDESGNPECLRICDFGFAKQLRAENGLLMTPCY 576
Query: 688 TPNYIAPEILTKK 726
T N++APE+L ++
Sbjct: 577 TANFVAPEVLKRQ 589
>AK222581-1|BAD96301.1| 556|Homo sapiens 3-phosphoinositide
dependent protein kinase-1 variant protein.
Length = 556
Score = 95.1 bits (226), Expect = 2e-19
Identities = 51/172 (29%), Positives = 88/172 (51%), Gaps = 2/172 (1%)
Frame = +1
Query: 217 RFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKHVVGF 396
+ G+G F+ +++A+++ YA + +E + L H V
Sbjct: 86 KILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKL 145
Query: 397 HSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRIIHRD 576
+ F+D +Y L K +++ ++ + E TRFY +I+ +YLH K IIHRD
Sbjct: 146 YFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSASEYLHGKGIIHRD 205
Query: 577 LKLGNLFLDDDLHVKIGDFGLAARIEYEGE--RKQTLCGTPNYIAPEILTKK 726
LK N+ L++D+H++I DFG A + E + R + GT Y++PE+LT+K
Sbjct: 206 LKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEK 257
>AF527555-1|AAM78553.1| 476|Homo sapiens CHK1 checkpoint homolog
(S. pombe) protein.
Length = 476
Score = 95.1 bits (226), Expect = 2e-19
Identities = 47/133 (35%), Positives = 75/133 (56%), Gaps = 2/133 (1%)
Frame = +1
Query: 334 EKMAQEISIHRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRF 513
E + +EI I++ L H++VV F+ + Y+ LE C + + + + EP+ +
Sbjct: 50 ENIKKEICINKMLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQR 109
Query: 514 YMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERK--QTLCG 687
+ HQ++ GV YLH I HRD+K NL LD+ ++KI DFGLA Y + +CG
Sbjct: 110 FFHQLMAGVVYLHGIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCG 169
Query: 688 TPNYIAPEILTKK 726
T Y+APE+L ++
Sbjct: 170 TLPYVAPELLKRR 182
>AF032874-1|AAB88852.1| 476|Homo sapiens protein kinase protein.
Length = 476
Score = 95.1 bits (226), Expect = 2e-19
Identities = 47/133 (35%), Positives = 75/133 (56%), Gaps = 2/133 (1%)
Frame = +1
Query: 334 EKMAQEISIHRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRF 513
E + +EI I++ L H++VV F+ + Y+ LE C + + + + EP+ +
Sbjct: 50 ENIKKEICINKMLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQR 109
Query: 514 YMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERK--QTLCG 687
+ HQ++ GV YLH I HRD+K NL LD+ ++KI DFGLA Y + +CG
Sbjct: 110 FFHQLMAGVVYLHGIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCG 169
Query: 688 TPNYIAPEILTKK 726
T Y+APE+L ++
Sbjct: 170 TLPYVAPELLKRR 182
>AF016582-1|AAC51736.1| 476|Homo sapiens Chk1 protein.
Length = 476
Score = 95.1 bits (226), Expect = 2e-19
Identities = 47/133 (35%), Positives = 75/133 (56%), Gaps = 2/133 (1%)
Frame = +1
Query: 334 EKMAQEISIHRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRF 513
E + +EI I++ L H++VV F+ + Y+ LE C + + + + EP+ +
Sbjct: 50 ENIKKEICINKMLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQR 109
Query: 514 YMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERK--QTLCG 687
+ HQ++ GV YLH I HRD+K NL LD+ ++KI DFGLA Y + +CG
Sbjct: 110 FFHQLMAGVVYLHGIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCG 169
Query: 688 TPNYIAPEILTKK 726
T Y+APE+L ++
Sbjct: 170 TLPYVAPELLKRR 182
>AB067488-1|BAB67794.1| 1265|Homo sapiens KIAA1901 protein protein.
Length = 1265
Score = 95.1 bits (226), Expect = 2e-19
Identities = 48/176 (27%), Positives = 94/176 (53%), Gaps = 2/176 (1%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKH 384
Y RL+ G+G F K ++ + Y E+ +E+++ +++H +
Sbjct: 11 YVRLQKIGEGSFGKAILVKSTEDGRQYV-IKEINISRMSSKEREESRREVAVLANMKHPN 69
Query: 385 VVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRF--YMHQILLGVQYLHSK 558
+V + FE++ ++YI+++ C+ + + +K + E + + QI L ++++H +
Sbjct: 70 IVQYRESFEENGSLYIVMDYCEGGDLFKRINAQKGVLFQEDQILDWFVQICLALKHVHDR 129
Query: 559 RIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
+I+HRD+K N+FL D V++GDFG+A + E +T GTP Y++PEI K
Sbjct: 130 KILHRDIKSQNIFLTKDGTVQLGDFGIARVLNSTVELARTCIGTPYYLSPEICENK 185
>AB032387-1|BAA84577.1| 476|Homo sapiens checkpoint kinase protein.
Length = 476
Score = 95.1 bits (226), Expect = 2e-19
Identities = 47/133 (35%), Positives = 75/133 (56%), Gaps = 2/133 (1%)
Frame = +1
Query: 334 EKMAQEISIHRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRF 513
E + +EI I++ L H++VV F+ + Y+ LE C + + + + EP+ +
Sbjct: 50 ENIKKEICINKMLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQR 109
Query: 514 YMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERK--QTLCG 687
+ HQ++ GV YLH I HRD+K NL LD+ ++KI DFGLA Y + +CG
Sbjct: 110 FFHQLMAGVVYLHGIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCG 169
Query: 688 TPNYIAPEILTKK 726
T Y+APE+L ++
Sbjct: 170 TLPYVAPELLKRR 182
>AB019692-1|BAA85625.1| 889|Homo sapiens protein kinase PKNbeta
protein.
Length = 889
Score = 95.1 bits (226), Expect = 2e-19
Identities = 59/184 (32%), Positives = 91/184 (49%), Gaps = 4/184 (2%)
Frame = +1
Query: 187 PQTNSTYQRLRFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHR 366
P ++ L G+G F K +Q + + YA E + E I
Sbjct: 553 PPRLQDFRCLAVLGRGHFGKVLLVQFKGTGKYYAIKALKKQEVLSRDEIESLYCEKRILE 612
Query: 367 SLQ---HKHVVGFHSFFEDSLNIYIILELCKKRS-MMELHKRRKAITEPETRFYMHQILL 534
++ H ++ F+ S + + E MM++H+ EP+ RFY+ ++L
Sbjct: 613 AVGCTGHPFLLSLLVCFQTSSHARFVTEFVPGGDLMMQIHE--DVFPEPQARFYVACVVL 670
Query: 535 GVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEI 714
G+Q+LH K+II+RDLKL NL LD +KI DFGL G+R T CGTP ++APE+
Sbjct: 671 GLQFLHEKKIIYRDLKLDNLLLDAQGFLKIADFGLCKEGIGFGDRTSTFCGTPEFLAPEV 730
Query: 715 LTKK 726
LT++
Sbjct: 731 LTQE 734
>Z92868-1|CAB07437.1| 686|Homo sapiens cGMP-dependent protein
kinase type I beta protein.
Length = 686
Score = 94.7 bits (225), Expect = 3e-19
Identities = 55/177 (31%), Positives = 87/177 (49%), Gaps = 1/177 (0%)
Frame = +1
Query: 199 STYQRLRFFGKGGFAKCYEIQ-DIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQ 375
S + + G GGF + +Q ++ +A E + E I +
Sbjct: 373 SDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGAH 432
Query: 376 HKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHS 555
+V + F+DS +Y+++E C + + + R + + TRFY ++ YLHS
Sbjct: 433 SDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHS 492
Query: 556 KRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
K II+RDLK NL LD + K+ DFG A +I + G++ T CGTP Y+APEI+ K
Sbjct: 493 KGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGF-GKKTWTFCGTPEYVAPEIILNK 548
>Z92867-1|CAB07436.1| 671|Homo sapiens cGMP-dependent protein
kinase type I alpha protein.
Length = 671
Score = 94.7 bits (225), Expect = 3e-19
Identities = 55/177 (31%), Positives = 87/177 (49%), Gaps = 1/177 (0%)
Frame = +1
Query: 199 STYQRLRFFGKGGFAKCYEIQ-DIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQ 375
S + + G GGF + +Q ++ +A E + E I +
Sbjct: 358 SDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGAH 417
Query: 376 HKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHS 555
+V + F+DS +Y+++E C + + + R + + TRFY ++ YLHS
Sbjct: 418 SDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHS 477
Query: 556 KRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
K II+RDLK NL LD + K+ DFG A +I + G++ T CGTP Y+APEI+ K
Sbjct: 478 KGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGF-GKKTWTFCGTPEYVAPEIILNK 533
>Y07512-1|CAA68810.1| 686|Homo sapiens protein ( Human mRNA for
type I beta cGMP-dependent protein kinase (EC
2.7.1.37). ).
Length = 686
Score = 94.7 bits (225), Expect = 3e-19
Identities = 55/177 (31%), Positives = 87/177 (49%), Gaps = 1/177 (0%)
Frame = +1
Query: 199 STYQRLRFFGKGGFAKCYEIQ-DIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQ 375
S + + G GGF + +Q ++ +A E + E I +
Sbjct: 373 SDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGAH 432
Query: 376 HKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHS 555
+V + F+DS +Y+++E C + + + R + + TRFY ++ YLHS
Sbjct: 433 SDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHS 492
Query: 556 KRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
K II+RDLK NL LD + K+ DFG A +I + G++ T CGTP Y+APEI+ K
Sbjct: 493 KGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGF-GKKTWTFCGTPEYVAPEIILNK 548
>X76104-1|CAA53712.1| 1431|Homo sapiens DAP-kinase protein.
Length = 1431
Score = 94.7 bits (225), Expect = 3e-19
Identities = 50/132 (37%), Positives = 80/132 (60%), Gaps = 4/132 (3%)
Frame = +1
Query: 334 EKMAQEISIHRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRF 513
E + +E+SI + +QH +V+ H +E+ ++ +ILEL + + ++++TE E
Sbjct: 59 EDIEREVSILKEIQHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATE 118
Query: 514 YMHQILLGVQYLHSKRIIHRDLKLGNLFLDD----DLHVKIGDFGLAARIEYEGERKQTL 681
++ QIL GV YLHS +I H DLK N+ L D +KI DFGLA +I++ E K +
Sbjct: 119 FLKQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFK-NI 177
Query: 682 CGTPNYIAPEIL 717
GTP ++APEI+
Sbjct: 178 FGTPEFVAPEIV 189
>D45864-1|BAA08297.1| 671|Homo sapiens cGMP-dependent protein
kinase type I alpha protein.
Length = 671
Score = 94.7 bits (225), Expect = 3e-19
Identities = 55/177 (31%), Positives = 87/177 (49%), Gaps = 1/177 (0%)
Frame = +1
Query: 199 STYQRLRFFGKGGFAKCYEIQ-DIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQ 375
S + + G GGF + +Q ++ +A E + E I +
Sbjct: 358 SDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGAH 417
Query: 376 HKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHS 555
+V + F+DS +Y+++E C + + + R + + TRFY ++ YLHS
Sbjct: 418 SDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHS 477
Query: 556 KRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
K II+RDLK NL LD + K+ DFG A +I + G++ T CGTP Y+APEI+ K
Sbjct: 478 KGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGF-GKKTWTFCGTPEYVAPEIILNK 533
>DQ436495-1|ABD96827.1| 1430|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1430
Score = 94.7 bits (225), Expect = 3e-19
Identities = 50/132 (37%), Positives = 80/132 (60%), Gaps = 4/132 (3%)
Frame = +1
Query: 334 EKMAQEISIHRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRF 513
E + +E+SI + +QH +V+ H +E+ ++ +ILEL + + ++++TE E
Sbjct: 59 EDIEREVSILKEIQHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATE 118
Query: 514 YMHQILLGVQYLHSKRIIHRDLKLGNLFLDD----DLHVKIGDFGLAARIEYEGERKQTL 681
++ QIL GV YLHS +I H DLK N+ L D +KI DFGLA +I++ E K +
Sbjct: 119 FLKQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFK-NI 177
Query: 682 CGTPNYIAPEIL 717
GTP ++APEI+
Sbjct: 178 FGTPEFVAPEIV 189
>BT006935-1|AAP35581.1| 367|Homo sapiens death-associated protein
kinase 1 protein.
Length = 367
Score = 94.7 bits (225), Expect = 3e-19
Identities = 50/132 (37%), Positives = 80/132 (60%), Gaps = 4/132 (3%)
Frame = +1
Query: 334 EKMAQEISIHRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRF 513
E + +E+SI + +QH +V+ H +E+ ++ +ILEL + + ++++TE E
Sbjct: 59 EDIEREVSILKEIQHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATE 118
Query: 514 YMHQILLGVQYLHSKRIIHRDLKLGNLFLDD----DLHVKIGDFGLAARIEYEGERKQTL 681
++ QIL GV YLHS +I H DLK N+ L D +KI DFGLA +I++ E K +
Sbjct: 119 FLKQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFK-NI 177
Query: 682 CGTPNYIAPEIL 717
GTP ++APEI+
Sbjct: 178 FGTPEFVAPEIV 189
>BC127090-1|AAI27091.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 94.7 bits (225), Expect = 3e-19
Identities = 55/177 (31%), Positives = 87/177 (49%), Gaps = 1/177 (0%)
Frame = +1
Query: 199 STYQRLRFFGKGGFAKCYEIQ-DIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQ 375
S + + G GGF + +Q ++ +A E + E I +
Sbjct: 373 SDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGAH 432
Query: 376 HKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHS 555
+V + F+DS +Y+++E C + + + R + + TRFY ++ YLHS
Sbjct: 433 SDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHS 492
Query: 556 KRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
K II+RDLK NL LD + K+ DFG A +I + G++ T CGTP Y+APEI+ K
Sbjct: 493 KGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGF-GKKTWTFCGTPEYVAPEIILNK 548
>BC113660-1|AAI13661.1| 1430|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1430
Score = 94.7 bits (225), Expect = 3e-19
Identities = 50/132 (37%), Positives = 80/132 (60%), Gaps = 4/132 (3%)
Frame = +1
Query: 334 EKMAQEISIHRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRF 513
E + +E+SI + +QH +V+ H +E+ ++ +ILEL + + ++++TE E
Sbjct: 59 EDIEREVSILKEIQHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATE 118
Query: 514 YMHQILLGVQYLHSKRIIHRDLKLGNLFLDD----DLHVKIGDFGLAARIEYEGERKQTL 681
++ QIL GV YLHS +I H DLK N+ L D +KI DFGLA +I++ E K +
Sbjct: 119 FLKQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFK-NI 177
Query: 682 CGTPNYIAPEIL 717
GTP ++APEI+
Sbjct: 178 FGTPEFVAPEIV 189
>BC000094-1|AAH00094.3| 482|Homo sapiens ribosomal protein S6
kinase, 70kDa, polypeptide 2 protein.
Length = 482
Score = 94.7 bits (225), Expect = 3e-19
Identities = 58/178 (32%), Positives = 90/178 (50%), Gaps = 5/178 (2%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASN---QIYAGXXXXXXXXXXXXXXEKMAQ-EISIHRSL 372
++ LR GKGG+ K ++++ + +IYA + E +I S+
Sbjct: 67 FELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILESV 126
Query: 373 QHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETR-FYMHQILLGVQYL 549
+H +V F+ +Y+ILE C + H R+ I +T FY+ +I L + +L
Sbjct: 127 KHPFIVELAYAFQTGGKLYLILE-CLSGGELFTHLEREGIFLEDTACFYLAEITLALGHL 185
Query: 550 HSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTK 723
HS+ II+RDLK N+ L H+K+ DFGL +EG T CGT Y+APEIL +
Sbjct: 186 HSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILVR 243
>AL928686-2|CAI40743.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 94.7 bits (225), Expect = 3e-19
Identities = 55/177 (31%), Positives = 87/177 (49%), Gaps = 1/177 (0%)
Frame = +1
Query: 199 STYQRLRFFGKGGFAKCYEIQ-DIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQ 375
S + + G GGF + +Q ++ +A E + E I +
Sbjct: 373 SDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGAH 432
Query: 376 HKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHS 555
+V + F+DS +Y+++E C + + + R + + TRFY ++ YLHS
Sbjct: 433 SDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHS 492
Query: 556 KRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
K II+RDLK NL LD + K+ DFG A +I + G++ T CGTP Y+APEI+ K
Sbjct: 493 KGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGF-GKKTWTFCGTPEYVAPEIILNK 548
>AL928686-1|CAI40742.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 94.7 bits (225), Expect = 3e-19
Identities = 55/177 (31%), Positives = 87/177 (49%), Gaps = 1/177 (0%)
Frame = +1
Query: 199 STYQRLRFFGKGGFAKCYEIQ-DIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQ 375
S + + G GGF + +Q ++ +A E + E I +
Sbjct: 346 SDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGAH 405
Query: 376 HKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHS 555
+V + F+DS +Y+++E C + + + R + + TRFY ++ YLHS
Sbjct: 406 SDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHS 465
Query: 556 KRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
K II+RDLK NL LD + K+ DFG A +I + G++ T CGTP Y+APEI+ K
Sbjct: 466 KGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGF-GKKTWTFCGTPEYVAPEIILNK 521
>AL731537-3|CAI17115.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 94.7 bits (225), Expect = 3e-19
Identities = 55/177 (31%), Positives = 87/177 (49%), Gaps = 1/177 (0%)
Frame = +1
Query: 199 STYQRLRFFGKGGFAKCYEIQ-DIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQ 375
S + + G GGF + +Q ++ +A E + E I +
Sbjct: 373 SDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGAH 432
Query: 376 HKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHS 555
+V + F+DS +Y+++E C + + + R + + TRFY ++ YLHS
Sbjct: 433 SDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHS 492
Query: 556 KRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
K II+RDLK NL LD + K+ DFG A +I + G++ T CGTP Y+APEI+ K
Sbjct: 493 KGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGF-GKKTWTFCGTPEYVAPEIILNK 548
>AL731537-2|CAI17114.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 94.7 bits (225), Expect = 3e-19
Identities = 55/177 (31%), Positives = 87/177 (49%), Gaps = 1/177 (0%)
Frame = +1
Query: 199 STYQRLRFFGKGGFAKCYEIQ-DIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQ 375
S + + G GGF + +Q ++ +A E + E I +
Sbjct: 346 SDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGAH 405
Query: 376 HKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHS 555
+V + F+DS +Y+++E C + + + R + + TRFY ++ YLHS
Sbjct: 406 SDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHS 465
Query: 556 KRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
K II+RDLK NL LD + K+ DFG A +I + G++ T CGTP Y+APEI+ K
Sbjct: 466 KGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGF-GKKTWTFCGTPEYVAPEIILNK 521
>AL591852-1|CAH71696.1| 1455|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1455
Score = 94.7 bits (225), Expect = 3e-19
Identities = 50/132 (37%), Positives = 80/132 (60%), Gaps = 4/132 (3%)
Frame = +1
Query: 334 EKMAQEISIHRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRF 513
E + +E+SI + +QH +V+ H +E+ ++ +ILEL + + ++++TE E
Sbjct: 59 EDIEREVSILKEIQHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATE 118
Query: 514 YMHQILLGVQYLHSKRIIHRDLKLGNLFLDD----DLHVKIGDFGLAARIEYEGERKQTL 681
++ QIL GV YLHS +I H DLK N+ L D +KI DFGLA +I++ E K +
Sbjct: 119 FLKQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFK-NI 177
Query: 682 CGTPNYIAPEIL 717
GTP ++APEI+
Sbjct: 178 FGTPEFVAPEIV 189
>AL391378-2|CAI39626.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 94.7 bits (225), Expect = 3e-19
Identities = 55/177 (31%), Positives = 87/177 (49%), Gaps = 1/177 (0%)
Frame = +1
Query: 199 STYQRLRFFGKGGFAKCYEIQ-DIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQ 375
S + + G GGF + +Q ++ +A E + E I +
Sbjct: 373 SDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGAH 432
Query: 376 HKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHS 555
+V + F+DS +Y+++E C + + + R + + TRFY ++ YLHS
Sbjct: 433 SDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHS 492
Query: 556 KRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
K II+RDLK NL LD + K+ DFG A +I + G++ T CGTP Y+APEI+ K
Sbjct: 493 KGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGF-GKKTWTFCGTPEYVAPEIILNK 548
>AL391378-1|CAI39625.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 94.7 bits (225), Expect = 3e-19
Identities = 55/177 (31%), Positives = 87/177 (49%), Gaps = 1/177 (0%)
Frame = +1
Query: 199 STYQRLRFFGKGGFAKCYEIQ-DIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQ 375
S + + G GGF + +Q ++ +A E + E I +
Sbjct: 346 SDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGAH 405
Query: 376 HKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHS 555
+V + F+DS +Y+++E C + + + R + + TRFY ++ YLHS
Sbjct: 406 SDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHS 465
Query: 556 KRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
K II+RDLK NL LD + K+ DFG A +I + G++ T CGTP Y+APEI+ K
Sbjct: 466 KGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGF-GKKTWTFCGTPEYVAPEIILNK 521
>AL161787-1|CAH73544.1| 1455|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1455
Score = 94.7 bits (225), Expect = 3e-19
Identities = 50/132 (37%), Positives = 80/132 (60%), Gaps = 4/132 (3%)
Frame = +1
Query: 334 EKMAQEISIHRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRF 513
E + +E+SI + +QH +V+ H +E+ ++ +ILEL + + ++++TE E
Sbjct: 59 EDIEREVSILKEIQHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATE 118
Query: 514 YMHQILLGVQYLHSKRIIHRDLKLGNLFLDD----DLHVKIGDFGLAARIEYEGERKQTL 681
++ QIL GV YLHS +I H DLK N+ L D +KI DFGLA +I++ E K +
Sbjct: 119 FLKQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFK-NI 177
Query: 682 CGTPNYIAPEIL 717
GTP ++APEI+
Sbjct: 178 FGTPEFVAPEIV 189
>AL160279-1|CAI16306.1| 1455|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1455
Score = 94.7 bits (225), Expect = 3e-19
Identities = 50/132 (37%), Positives = 80/132 (60%), Gaps = 4/132 (3%)
Frame = +1
Query: 334 EKMAQEISIHRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRF 513
E + +E+SI + +QH +V+ H +E+ ++ +ILEL + + ++++TE E
Sbjct: 59 EDIEREVSILKEIQHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATE 118
Query: 514 YMHQILLGVQYLHSKRIIHRDLKLGNLFLDD----DLHVKIGDFGLAARIEYEGERKQTL 681
++ QIL GV YLHS +I H DLK N+ L D +KI DFGLA +I++ E K +
Sbjct: 119 FLKQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFK-NI 177
Query: 682 CGTPNYIAPEIL 717
GTP ++APEI+
Sbjct: 178 FGTPEFVAPEIV 189
>AL157399-2|CAI41305.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 94.7 bits (225), Expect = 3e-19
Identities = 55/177 (31%), Positives = 87/177 (49%), Gaps = 1/177 (0%)
Frame = +1
Query: 199 STYQRLRFFGKGGFAKCYEIQ-DIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQ 375
S + + G GGF + +Q ++ +A E + E I +
Sbjct: 373 SDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGAH 432
Query: 376 HKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHS 555
+V + F+DS +Y+++E C + + + R + + TRFY ++ YLHS
Sbjct: 433 SDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHS 492
Query: 556 KRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
K II+RDLK NL LD + K+ DFG A +I + G++ T CGTP Y+APEI+ K
Sbjct: 493 KGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGF-GKKTWTFCGTPEYVAPEIILNK 548
>AL157399-1|CAI41304.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 94.7 bits (225), Expect = 3e-19
Identities = 55/177 (31%), Positives = 87/177 (49%), Gaps = 1/177 (0%)
Frame = +1
Query: 199 STYQRLRFFGKGGFAKCYEIQ-DIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQ 375
S + + G GGF + +Q ++ +A E + E I +
Sbjct: 346 SDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGAH 405
Query: 376 HKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHS 555
+V + F+DS +Y+++E C + + + R + + TRFY ++ YLHS
Sbjct: 406 SDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHS 465
Query: 556 KRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
K II+RDLK NL LD + K+ DFG A +I + G++ T CGTP Y+APEI+ K
Sbjct: 466 KGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGF-GKKTWTFCGTPEYVAPEIILNK 521
>AF099739-1|AAD20990.1| 482|Homo sapiens S6 kinase-related kinase
protein.
Length = 482
Score = 94.7 bits (225), Expect = 3e-19
Identities = 58/178 (32%), Positives = 90/178 (50%), Gaps = 5/178 (2%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASN---QIYAGXXXXXXXXXXXXXXEKMAQ-EISIHRSL 372
++ LR GKGG+ K ++++ + +IYA + E +I S+
Sbjct: 67 FELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILESV 126
Query: 373 QHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETR-FYMHQILLGVQYL 549
+H +V F+ +Y+ILE C + H R+ I +T FY+ +I L + +L
Sbjct: 127 KHPFIVELAYAFQTGGKLYLILE-CLSGGELFTHLEREGIFLEDTACFYLAEITLALGHL 185
Query: 550 HSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTK 723
HS+ II+RDLK N+ L H+K+ DFGL +EG T CGT Y+APEIL +
Sbjct: 186 HSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILVR 243
>AF076931-1|AAD46063.1| 482|Homo sapiens serine/threonine kinase 14
beta protein.
Length = 482
Score = 94.7 bits (225), Expect = 3e-19
Identities = 58/178 (32%), Positives = 90/178 (50%), Gaps = 5/178 (2%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASN---QIYAGXXXXXXXXXXXXXXEKMAQ-EISIHRSL 372
++ LR GKGG+ K ++++ + +IYA + E +I S+
Sbjct: 67 FELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILESV 126
Query: 373 QHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETR-FYMHQILLGVQYL 549
+H +V F+ +Y+ILE C + H R+ I +T FY+ +I L + +L
Sbjct: 127 KHPFIVELAYAFQTGGKLYLILE-CLSGGELFTHLEREGIFLEDTACFYLAEITLALGHL 185
Query: 550 HSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTK 723
HS+ II+RDLK N+ L H+K+ DFGL +EG T CGT Y+APEIL +
Sbjct: 186 HSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILVR 243
>AB208871-1|BAD92108.1| 1433|Homo sapiens Hypothetical protein
DKFZp781I035 variant protein.
Length = 1433
Score = 94.7 bits (225), Expect = 3e-19
Identities = 50/132 (37%), Positives = 80/132 (60%), Gaps = 4/132 (3%)
Frame = +1
Query: 334 EKMAQEISIHRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRF 513
E + +E+SI + +QH +V+ H +E+ ++ +ILEL + + ++++TE E
Sbjct: 62 EDIEREVSILKEIQHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATE 121
Query: 514 YMHQILLGVQYLHSKRIIHRDLKLGNLFLDD----DLHVKIGDFGLAARIEYEGERKQTL 681
++ QIL GV YLHS +I H DLK N+ L D +KI DFGLA +I++ E K +
Sbjct: 122 FLKQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFK-NI 180
Query: 682 CGTPNYIAPEIL 717
GTP ++APEI+
Sbjct: 181 FGTPEFVAPEIV 192
>AB016869-1|BAA34402.1| 495|Homo sapiens p70 ribosomal S6 kinase
beta protein.
Length = 495
Score = 94.7 bits (225), Expect = 3e-19
Identities = 58/178 (32%), Positives = 90/178 (50%), Gaps = 5/178 (2%)
Frame = +1
Query: 205 YQRLRFFGKGGFAKCYEIQDIASN---QIYAGXXXXXXXXXXXXXXEKMAQ-EISIHRSL 372
++ LR GKGG+ K ++++ + +IYA + E +I S+
Sbjct: 80 FELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILESV 139
Query: 373 QHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETR-FYMHQILLGVQYL 549
+H +V F+ +Y+ILE C + H R+ I +T FY+ +I L + +L
Sbjct: 140 KHPFIVELAYAFQTGGKLYLILE-CLSGGELFTHLEREGIFLEDTACFYLAEITLALGHL 198
Query: 550 HSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTK 723
HS+ II+RDLK N+ L H+K+ DFGL +EG T CGT Y+APEIL +
Sbjct: 199 HSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILVR 256
>Z98049-1|CAI20579.1| 733|Homo sapiens ribosomal protein S6 kinase,
90kDa, polypeptide 2 protein.
Length = 733
Score = 94.3 bits (224), Expect = 4e-19
Identities = 49/179 (27%), Positives = 90/179 (50%), Gaps = 3/179 (1%)
Frame = +1
Query: 199 STYQRLRFFGKGGFAKCYEIQDIASN---QIYAGXXXXXXXXXXXXXXEKMAQEISIHRS 369
S ++ L+ G+G + K + ++ + + Q+YA + E I
Sbjct: 57 SQFELLKVLGQGSYGKVFLVRKVKGSDAGQLYA-MKVLKKATLKVRDRVRSKMERDILAE 115
Query: 370 LQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYL 549
+ H +V H F+ +Y+IL+ + + + TE + +FY+ ++ L + +L
Sbjct: 116 VNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHL 175
Query: 550 HSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
HS II+RDLK N+ LD++ H+KI DFGL+ +R + CGT Y+APE++ ++
Sbjct: 176 HSLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRR 234
Score = 70.9 bits (166), Expect = 4e-12
Identities = 37/133 (27%), Positives = 72/133 (54%), Gaps = 5/133 (3%)
Frame = +1
Query: 343 AQEISIH-RSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYM 519
++EI I R QH +++ ++D +Y+++EL + +++ R++ +E E +
Sbjct: 454 SEEIEILLRYGQHPNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVL 513
Query: 520 HQILLGVQYLHSKRIIHRDLKLGNLFLDDDL----HVKIGDFGLAARIEYEGERKQTLCG 687
I + YLHS+ ++HRDLK N+ D+ +++ DFG A ++ T C
Sbjct: 514 CTITKTMDYLHSQGVVHRDLKPSNILYRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCY 573
Query: 688 TPNYIAPEILTKK 726
T N++APE+L ++
Sbjct: 574 TANFVAPEVLKRQ 586
>X85106-1|CAA59427.1| 733|Homo sapiens ribosomal S6 kinase protein.
Length = 733
Score = 94.3 bits (224), Expect = 4e-19
Identities = 49/179 (27%), Positives = 90/179 (50%), Gaps = 3/179 (1%)
Frame = +1
Query: 199 STYQRLRFFGKGGFAKCYEIQDIASN---QIYAGXXXXXXXXXXXXXXEKMAQEISIHRS 369
S ++ L+ G+G + K + ++ + + Q+YA + E I
Sbjct: 57 SQFELLKVLGQGSYGKVFLVRKVKGSDAGQLYA-MKVLKKATLKVRDRVRSKMERDILAE 115
Query: 370 LQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYL 549
+ H +V H F+ +Y+IL+ + + + TE + +FY+ ++ L + +L
Sbjct: 116 VNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHL 175
Query: 550 HSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
HS II+RDLK N+ LD++ H+KI DFGL+ +R + CGT Y+APE++ ++
Sbjct: 176 HSLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRR 234
Score = 70.9 bits (166), Expect = 4e-12
Identities = 37/133 (27%), Positives = 72/133 (54%), Gaps = 5/133 (3%)
Frame = +1
Query: 343 AQEISIH-RSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYM 519
++EI I R QH +++ ++D +Y+++EL + +++ R++ +E E +
Sbjct: 454 SEEIEILLRYGQHPNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVL 513
Query: 520 HQILLGVQYLHSKRIIHRDLKLGNLFLDDDL----HVKIGDFGLAARIEYEGERKQTLCG 687
I + YLHS+ ++HRDLK N+ D+ +++ DFG A ++ T C
Sbjct: 514 CTITKTMDYLHSQGVVHRDLKPSNILYRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCY 573
Query: 688 TPNYIAPEILTKK 726
T N++APE+L ++
Sbjct: 574 TANFVAPEVLKRQ 586
>L07598-1|AAC82496.1| 540|Homo sapiens ribosomal protein S6 kinase
2 protein.
Length = 540
Score = 94.3 bits (224), Expect = 4e-19
Identities = 49/179 (27%), Positives = 90/179 (50%), Gaps = 3/179 (1%)
Frame = +1
Query: 199 STYQRLRFFGKGGFAKCYEIQDIASN---QIYAGXXXXXXXXXXXXXXEKMAQEISIHRS 369
S ++ L+ G+G + K + ++ + + Q+YA + E I
Sbjct: 58 SQFELLKVLGQGSYGKVFLVRKVKGSDAGQLYA-MKVLKKATLKVRDRVRSKMERDILAE 116
Query: 370 LQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYL 549
+ H +V H F+ +Y+IL+ + + + TE + +FY+ ++ L + +L
Sbjct: 117 VNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHL 176
Query: 550 HSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
HS II+RDLK N+ LD++ H+KI DFGL+ +R + CGT Y+APE++ ++
Sbjct: 177 HSLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRR 235
Score = 49.6 bits (113), Expect = 1e-05
Identities = 24/85 (28%), Positives = 48/85 (56%), Gaps = 1/85 (1%)
Frame = +1
Query: 343 AQEISIH-RSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYM 519
++EI I R QH +++ ++D +Y+++EL + +++ R++ +E E +
Sbjct: 455 SEEIEILLRYGQHPNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVL 514
Query: 520 HQILLGVQYLHSKRIIHRDLKLGNL 594
I + YLHS+ ++HRDLK N+
Sbjct: 515 CTITKTMDYLHSQGVVHRDLKPSNI 539
>BC002363-1|AAH02363.1| 733|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 2 protein.
Length = 733
Score = 94.3 bits (224), Expect = 4e-19
Identities = 49/179 (27%), Positives = 90/179 (50%), Gaps = 3/179 (1%)
Frame = +1
Query: 199 STYQRLRFFGKGGFAKCYEIQDIASN---QIYAGXXXXXXXXXXXXXXEKMAQEISIHRS 369
S ++ L+ G+G + K + ++ + + Q+YA + E I
Sbjct: 57 SQFELLKVLGQGSYGKVFLVRKVKGSDAGQLYA-MKVLKKATLKVRDRVRSKMERDILAE 115
Query: 370 LQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYL 549
+ H +V H F+ +Y+IL+ + + + TE + +FY+ ++ L + +L
Sbjct: 116 VNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHL 175
Query: 550 HSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
HS II+RDLK N+ LD++ H+KI DFGL+ +R + CGT Y+APE++ ++
Sbjct: 176 HSLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRR 234
Score = 70.9 bits (166), Expect = 4e-12
Identities = 37/133 (27%), Positives = 72/133 (54%), Gaps = 5/133 (3%)
Frame = +1
Query: 343 AQEISIH-RSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYM 519
++EI I R QH +++ ++D +Y+++EL + +++ R++ +E E +
Sbjct: 454 SEEIEILLRYGQHPNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVL 513
Query: 520 HQILLGVQYLHSKRIIHRDLKLGNLFLDDDL----HVKIGDFGLAARIEYEGERKQTLCG 687
I + YLHS+ ++HRDLK N+ D+ +++ DFG A ++ T C
Sbjct: 514 CTITKTMDYLHSQGVVHRDLKPSNILYRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCY 573
Query: 688 TPNYIAPEILTKK 726
T N++APE+L ++
Sbjct: 574 TANFVAPEVLKRQ 586
>AL022069-2|CAI19651.1| 733|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 2 protein.
Length = 733
Score = 94.3 bits (224), Expect = 4e-19
Identities = 49/179 (27%), Positives = 90/179 (50%), Gaps = 3/179 (1%)
Frame = +1
Query: 199 STYQRLRFFGKGGFAKCYEIQDIASN---QIYAGXXXXXXXXXXXXXXEKMAQEISIHRS 369
S ++ L+ G+G + K + ++ + + Q+YA + E I
Sbjct: 57 SQFELLKVLGQGSYGKVFLVRKVKGSDAGQLYA-MKVLKKATLKVRDRVRSKMERDILAE 115
Query: 370 LQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYL 549
+ H +V H F+ +Y+IL+ + + + TE + +FY+ ++ L + +L
Sbjct: 116 VNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHL 175
Query: 550 HSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
HS II+RDLK N+ LD++ H+KI DFGL+ +R + CGT Y+APE++ ++
Sbjct: 176 HSLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRR 234
Score = 70.9 bits (166), Expect = 4e-12
Identities = 37/133 (27%), Positives = 72/133 (54%), Gaps = 5/133 (3%)
Frame = +1
Query: 343 AQEISIH-RSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYM 519
++EI I R QH +++ ++D +Y+++EL + +++ R++ +E E +
Sbjct: 454 SEEIEILLRYGQHPNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVL 513
Query: 520 HQILLGVQYLHSKRIIHRDLKLGNLFLDDDL----HVKIGDFGLAARIEYEGERKQTLCG 687
I + YLHS+ ++HRDLK N+ D+ +++ DFG A ++ T C
Sbjct: 514 CTITKTMDYLHSQGVVHRDLKPSNILYRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCY 573
Query: 688 TPNYIAPEILTKK 726
T N++APE+L ++
Sbjct: 574 TANFVAPEVLKRQ 586
>AB209116-1|BAD92353.1| 806|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 2 isoform b variant protein.
Length = 806
Score = 94.3 bits (224), Expect = 4e-19
Identities = 49/179 (27%), Positives = 90/179 (50%), Gaps = 3/179 (1%)
Frame = +1
Query: 199 STYQRLRFFGKGGFAKCYEIQDIASN---QIYAGXXXXXXXXXXXXXXEKMAQEISIHRS 369
S ++ L+ G+G + K + ++ + + Q+YA + E I
Sbjct: 130 SQFELLKVLGQGSYGKVFLVRKVKGSDAGQLYA-MKVLKKATLKVRDRVRSKMERDILAE 188
Query: 370 LQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYL 549
+ H +V H F+ +Y+IL+ + + + TE + +FY+ ++ L + +L
Sbjct: 189 VNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHL 248
Query: 550 HSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIAPEILTKK 726
HS II+RDLK N+ LD++ H+KI DFGL+ +R + CGT Y+APE++ ++
Sbjct: 249 HSLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRR 307
Score = 70.9 bits (166), Expect = 4e-12
Identities = 37/133 (27%), Positives = 72/133 (54%), Gaps = 5/133 (3%)
Frame = +1
Query: 343 AQEISIH-RSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYM 519
++EI I R QH +++ ++D +Y+++EL + +++ R++ +E E +
Sbjct: 527 SEEIEILLRYGQHPNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVL 586
Query: 520 HQILLGVQYLHSKRIIHRDLKLGNLFLDDDL----HVKIGDFGLAARIEYEGERKQTLCG 687
I + YLHS+ ++HRDLK N+ D+ +++ DFG A ++ T C
Sbjct: 587 CTITKTMDYLHSQGVVHRDLKPSNILYRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCY 646
Query: 688 TPNYIAPEILTKK 726
T N++APE+L ++
Sbjct: 647 TANFVAPEVLKRQ 659
>CR456418-1|CAG30304.1| 586|Homo sapiens CHEK2 protein.
Length = 586
Score = 93.9 bits (223), Expect = 5e-19
Identities = 52/126 (41%), Positives = 75/126 (59%), Gaps = 3/126 (2%)
Frame = +1
Query: 349 EISIHRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQI 528
EI I + L H ++ +FF D+ + YI+LEL + + + K + E + Y +Q+
Sbjct: 316 EIEILKKLNHPCIIKIKNFF-DAEDYYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQM 374
Query: 529 LLGVQYLHSKRIIHRDLKLGNLFL---DDDLHVKIGDFGLAARIEYEGERKQTLCGTPNY 699
LL VQYLH IIHRDLK N+ L ++D +KI DFG ++I E +TLCGTP Y
Sbjct: 375 LLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFG-HSKILGETSLMRTLCGTPTY 433
Query: 700 IAPEIL 717
+APE+L
Sbjct: 434 LAPEVL 439
>BC038504-1|AAH38504.1| 783|Homo sapiens SNF1-like kinase protein.
Length = 783
Score = 93.9 bits (223), Expect = 5e-19
Identities = 46/131 (35%), Positives = 67/131 (51%)
Frame = +1
Query: 334 EKMAQEISIHRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRF 513
EK+ +E+ + + L H H++ + E +YI+ E K M + ++E E R
Sbjct: 69 EKIYREVQLMKLLNHPHIIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARK 128
Query: 514 YMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTP 693
QIL V+Y H I+HRDLK NL LD ++ +K+ DFG GE T CG+P
Sbjct: 129 KFWQILSAVEYCHDHHIVHRDLKTENLLLDGNMDIKLADFGF-GNFYKSGEPLSTWCGSP 187
Query: 694 NYIAPEILTKK 726
Y APE+ K
Sbjct: 188 PYAAPEVFEGK 198
>BC004207-1|AAH04207.1| 543|Homo sapiens CHK2 checkpoint homolog
(S. pombe) protein.
Length = 543
Score = 93.9 bits (223), Expect = 5e-19
Identities = 52/126 (41%), Positives = 75/126 (59%), Gaps = 3/126 (2%)
Frame = +1
Query: 349 EISIHRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQI 528
EI I + L H ++ +FF D+ + YI+LEL + + + K + E + Y +Q+
Sbjct: 273 EIEILKKLNHPCIIKIKNFF-DAEDYYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQM 331
Query: 529 LLGVQYLHSKRIIHRDLKLGNLFL---DDDLHVKIGDFGLAARIEYEGERKQTLCGTPNY 699
LL VQYLH IIHRDLK N+ L ++D +KI DFG ++I E +TLCGTP Y
Sbjct: 332 LLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFG-HSKILGETSLMRTLCGTPTY 390
Query: 700 IAPEIL 717
+APE+L
Sbjct: 391 LAPEVL 396
>AY800241-1|AAV41895.1| 543|Homo sapiens CHK2 checkpoint homolog
(S. pombe) protein.
Length = 543
Score = 93.9 bits (223), Expect = 5e-19
Identities = 52/126 (41%), Positives = 75/126 (59%), Gaps = 3/126 (2%)
Frame = +1
Query: 349 EISIHRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQI 528
EI I + L H ++ +FF D+ + YI+LEL + + + K + E + Y +Q+
Sbjct: 273 EIEILKKLNHPCIIKIKNFF-DAEDYYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQM 331
Query: 529 LLGVQYLHSKRIIHRDLKLGNLFL---DDDLHVKIGDFGLAARIEYEGERKQTLCGTPNY 699
LL VQYLH IIHRDLK N+ L ++D +KI DFG ++I E +TLCGTP Y
Sbjct: 332 LLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFG-HSKILGETSLMRTLCGTPTY 390
Query: 700 IAPEIL 717
+APE+L
Sbjct: 391 LAPEVL 396
>AY551303-1|AAS58464.1| 452|Homo sapiens protein kinase Chk2
transcript variant del2-3 protein.
Length = 452
Score = 93.9 bits (223), Expect = 5e-19
Identities = 52/126 (41%), Positives = 75/126 (59%), Gaps = 3/126 (2%)
Frame = +1
Query: 349 EISIHRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQI 528
EI I + L H ++ +FF D+ + YI+LEL + + + K + E + Y +Q+
Sbjct: 182 EIEILKKLNHPCIIKIKNFF-DAEDYYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQM 240
Query: 529 LLGVQYLHSKRIIHRDLKLGNLFL---DDDLHVKIGDFGLAARIEYEGERKQTLCGTPNY 699
LL VQYLH IIHRDLK N+ L ++D +KI DFG ++I E +TLCGTP Y
Sbjct: 241 LLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFG-HSKILGETSLMRTLCGTPTY 299
Query: 700 IAPEIL 717
+APE+L
Sbjct: 300 LAPEVL 305
>AY551297-1|AAS58458.1| 586|Homo sapiens protein kinase Chk2
transcript variant insX protein.
Length = 586
Score = 93.9 bits (223), Expect = 5e-19
Identities = 52/126 (41%), Positives = 75/126 (59%), Gaps = 3/126 (2%)
Frame = +1
Query: 349 EISIHRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQI 528
EI I + L H ++ +FF D+ + YI+LEL + + + K + E + Y +Q+
Sbjct: 316 EIEILKKLNHPCIIKIKNFF-DAEDYYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQM 374
Query: 529 LLGVQYLHSKRIIHRDLKLGNLFL---DDDLHVKIGDFGLAARIEYEGERKQTLCGTPNY 699
LL VQYLH IIHRDLK N+ L ++D +KI DFG ++I E +TLCGTP Y
Sbjct: 375 LLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFG-HSKILGETSLMRTLCGTPTY 433
Query: 700 IAPEIL 717
+APE+L
Sbjct: 434 LAPEVL 439
>AL121825-1|CAH73823.1| 543|Homo sapiens CHK2 checkpoint homolog
(S. pombe) protein.
Length = 543
Score = 93.9 bits (223), Expect = 5e-19
Identities = 52/126 (41%), Positives = 75/126 (59%), Gaps = 3/126 (2%)
Frame = +1
Query: 349 EISIHRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQI 528
EI I + L H ++ +FF D+ + YI+LEL + + + K + E + Y +Q+
Sbjct: 273 EIEILKKLNHPCIIKIKNFF-DAEDYYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQM 331
Query: 529 LLGVQYLHSKRIIHRDLKLGNLFL---DDDLHVKIGDFGLAARIEYEGERKQTLCGTPNY 699
LL VQYLH IIHRDLK N+ L ++D +KI DFG ++I E +TLCGTP Y
Sbjct: 332 LLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFG-HSKILGETSLMRTLCGTPTY 390
Query: 700 IAPEIL 717
+APE+L
Sbjct: 391 LAPEVL 396
>AL117330-1|CAH73875.1| 543|Homo sapiens CHK2 checkpoint homolog
(S. pombe) protein.
Length = 543
Score = 93.9 bits (223), Expect = 5e-19
Identities = 52/126 (41%), Positives = 75/126 (59%), Gaps = 3/126 (2%)
Frame = +1
Query: 349 EISIHRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQI 528
EI I + L H ++ +FF D+ + YI+LEL + + + K + E + Y +Q+
Sbjct: 273 EIEILKKLNHPCIIKIKNFF-DAEDYYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQM 331
Query: 529 LLGVQYLHSKRIIHRDLKLGNLFL---DDDLHVKIGDFGLAARIEYEGERKQTLCGTPNY 699
LL VQYLH IIHRDLK N+ L ++D +KI DFG ++I E +TLCGTP Y
Sbjct: 332 LLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFG-HSKILGETSLMRTLCGTPTY 390
Query: 700 IAPEIL 717
+APE+L
Sbjct: 391 LAPEVL 396
>AK131076-1|BAC85126.1| 764|Homo sapiens FLJ00263 protein protein.
Length = 764
Score = 93.9 bits (223), Expect = 5e-19
Identities = 46/131 (35%), Positives = 67/131 (51%)
Frame = +1
Query: 334 EKMAQEISIHRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRF 513
EK+ +E+ + + L H H++ + E +YI+ E K M + ++E E R
Sbjct: 50 EKIYREVQLMKLLNHPHIIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARK 109
Query: 514 YMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTP 693
QIL V+Y H I+HRDLK NL LD ++ +K+ DFG GE T CG+P
Sbjct: 110 KFWQILSAVEYCHDHHIVHRDLKTENLLLDGNMDIKLADFGF-GNFYKSGEPLSTWCGSP 168
Query: 694 NYIAPEILTKK 726
Y APE+ K
Sbjct: 169 PYAAPEVFEGK 179
>AJ785968-1|CAH05056.1| 396|Homo sapiens PDPK2 protein protein.
Length = 396
Score = 93.9 bits (223), Expect = 5e-19
Identities = 50/172 (29%), Positives = 89/172 (51%), Gaps = 2/172 (1%)
Frame = +1
Query: 217 RFFGKGGFAKCYEIQDIASNQIYAGXXXXXXXXXXXXXXEKMAQEISIHRSLQHKHVVGF 396
+ G+G F+ +++A+++ YA + +E + L H V
Sbjct: 59 KILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKL 118
Query: 397 HSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQILLGVQYLHSKRIIHRD 576
+ F+D +Y L K +++ ++ + E TRFY +I+ ++YLH K IIHRD
Sbjct: 119 YFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRD 178
Query: 577 LKLGNLFLDDDLHVKIGDFGLAARIEYEGE--RKQTLCGTPNYIAPEILTKK 726
LK N+ L++D++++I DFG A + E + R + GT Y++PE+LT+K
Sbjct: 179 LKPENILLNEDMYIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEK 230
>AJ131197-1|CAA10319.1| 543|Homo sapiens protein kinase protein.
Length = 543
Score = 93.9 bits (223), Expect = 5e-19
Identities = 52/126 (41%), Positives = 75/126 (59%), Gaps = 3/126 (2%)
Frame = +1
Query: 349 EISIHRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQI 528
EI I + L H ++ +FF D+ + YI+LEL + + + K + E + Y +Q+
Sbjct: 273 EIEILKKLNHPCIIKIKNFF-DAEDYYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQM 331
Query: 529 LLGVQYLHSKRIIHRDLKLGNLFL---DDDLHVKIGDFGLAARIEYEGERKQTLCGTPNY 699
LL VQYLH IIHRDLK N+ L ++D +KI DFG ++I E +TLCGTP Y
Sbjct: 332 LLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFG-HSKILGETSLMRTLCGTPTY 390
Query: 700 IAPEIL 717
+APE+L
Sbjct: 391 LAPEVL 396
>AF217975-1|AAG17218.1| 322|Homo sapiens unknown protein.
Length = 322
Score = 93.9 bits (223), Expect = 5e-19
Identities = 52/126 (41%), Positives = 75/126 (59%), Gaps = 3/126 (2%)
Frame = +1
Query: 349 EISIHRSLQHKHVVGFHSFFEDSLNIYIILELCKKRSMMELHKRRKAITEPETRFYMHQI 528
EI I + L H ++ +FF D+ + YI+LEL + + + K + E + Y +Q+
Sbjct: 52 EIEILKKLNHPCIIKIKNFF-DAEDYYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQM 110
Query: 529 LLGVQYLHSKRIIHRDLKLGNLFL---DDDLHVKIGDFGLAARIEYEGERKQTLCGTPNY 699
LL VQYLH IIHRDLK N+ L ++D +KI DFG ++I E +TLCGTP Y
Sbjct: 111 LLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFG-HSKILGETSLMRTLCGTPTY 169
Query: 700 IAPEIL 717
+APE+L
Sbjct: 170 LAPEVL 175
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 104,345,357
Number of Sequences: 237096
Number of extensions: 2227545
Number of successful extensions: 8535
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 6737
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7194
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8567175942
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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