Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmte19f02
(657 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI0000D5551D Cluster: PREDICTED: similar to Pyruvate k... 205 6e-52
UniRef50_Q4SVB7 Cluster: Pyruvate kinase; n=1; Tetraodon nigrovi... 200 2e-50
UniRef50_P30613 Cluster: Pyruvate kinase isozymes R/L; n=167; Fu... 192 6e-48
UniRef50_Q27686 Cluster: Pyruvate kinase; n=16; Kinetoplastida|R... 153 3e-36
UniRef50_Q9VD23 Cluster: Pyruvate kinase; n=5; Coelomata|Rep: Py... 147 2e-34
UniRef50_Q9VQH0 Cluster: Pyruvate kinase; n=3; Sophophora|Rep: P... 145 7e-34
UniRef50_Q7RVA8 Cluster: Pyruvate kinase; n=11; Ascomycota|Rep: ... 136 6e-31
UniRef50_Q42806 Cluster: Pyruvate kinase, cytosolic isozyme; n=6... 127 3e-28
UniRef50_Q9M057 Cluster: Pyruvate kinase; n=11; Magnoliophyta|Re... 124 2e-27
UniRef50_P80885 Cluster: Pyruvate kinase; n=161; Bacteria|Rep: P... 120 2e-26
UniRef50_O44006 Cluster: Pyruvate kinase; n=10; cellular organis... 118 2e-25
UniRef50_P52489 Cluster: Pyruvate kinase 2; n=33; Dikarya|Rep: P... 113 5e-24
UniRef50_Q2TSW8 Cluster: Pyruvate kinase; n=4; stramenopiles|Rep... 112 6e-24
UniRef50_Q4U977 Cluster: Pyruvate kinase, putative; n=3; Piropla... 111 1e-23
UniRef50_P77983 Cluster: Pyruvate kinase I; n=29; Bacteria|Rep: ... 111 1e-23
UniRef50_Q8EX62 Cluster: Pyruvate kinase; n=5; Bacteria|Rep: Pyr... 110 2e-23
UniRef50_Q090R5 Cluster: Pyruvate kinase; n=1; Stigmatella auran... 109 6e-23
UniRef50_Q1FK29 Cluster: Pyruvate kinase; n=4; Clostridiales|Rep... 109 8e-23
UniRef50_Q22Z06 Cluster: Pyruvate kinase family protein; n=3; Ol... 106 5e-22
UniRef50_A4E9R2 Cluster: Pyruvate kinase; n=1; Collinsella aerof... 104 2e-21
UniRef50_A7HIL5 Cluster: Pyruvate kinase; n=9; Bacteria|Rep: Pyr... 101 2e-20
UniRef50_Q8TJ98 Cluster: Pyruvate kinase; n=2; Methanomicrobia|R... 101 2e-20
UniRef50_Q6MLB5 Cluster: Pyruvate kinase; n=1; Bdellovibrio bact... 99 5e-20
UniRef50_Q2TSW6 Cluster: Pyruvate kinase; n=1; Achlya bisexualis... 99 5e-20
UniRef50_Q8PYY4 Cluster: Pyruvate kinase; n=3; Methanosarcinacea... 99 5e-20
UniRef50_Q9KUN0 Cluster: Pyruvate kinase; n=24; cellular organis... 99 8e-20
UniRef50_Q55863 Cluster: Pyruvate kinase 1; n=5; Cyanobacteria|R... 98 2e-19
UniRef50_Q04668 Cluster: Pyruvate kinase; n=2; Leishmania brazil... 97 2e-19
UniRef50_UPI0000DB6F59 Cluster: PREDICTED: similar to Pyruvate k... 97 3e-19
UniRef50_Q2IHE2 Cluster: Pyruvate kinase; n=1; Anaeromyxobacter ... 97 4e-19
UniRef50_Q46078 Cluster: Pyruvate kinase; n=19; Actinobacteria (... 96 6e-19
UniRef50_Q3JCE7 Cluster: Pyruvate kinase; n=1; Nitrosococcus oce... 95 1e-18
UniRef50_Q2S3S2 Cluster: Pyruvate kinase; n=1; Salinibacter rube... 94 2e-18
UniRef50_Q1K4D5 Cluster: Pyruvate kinase; n=1; Desulfuromonas ac... 93 5e-18
UniRef50_A3I0G9 Cluster: Pyruvate kinase; n=3; Flexibacteraceae|... 93 7e-18
UniRef50_Q0W8N0 Cluster: Pyruvate kinase; n=7; cellular organism... 92 9e-18
UniRef50_Q1AXJ8 Cluster: Pyruvate kinase; n=1; Rubrobacter xylan... 92 1e-17
UniRef50_P94685 Cluster: Pyruvate kinase; n=8; Chlamydiaceae|Rep... 92 1e-17
UniRef50_UPI00015BD1E0 Cluster: UPI00015BD1E0 related cluster; n... 91 2e-17
UniRef50_Q08SK3 Cluster: Pyruvate kinase; n=2; Cystobacterineae|... 91 2e-17
UniRef50_A7CUA8 Cluster: Pyruvate kinase; n=1; Opitutaceae bacte... 91 2e-17
UniRef50_A5C814 Cluster: Pyruvate kinase; n=1; Vitis vinifera|Re... 91 2e-17
UniRef50_Q747D6 Cluster: Pyruvate kinase; n=6; Desulfuromonadale... 91 3e-17
UniRef50_Q1Q4I4 Cluster: Strongly similar to pyruvate kinase; n=... 90 4e-17
UniRef50_Q1NTW3 Cluster: Pyruvate kinase; n=1; delta proteobacte... 90 4e-17
UniRef50_Q1IHI1 Cluster: Pyruvate kinase; n=2; Bacteria|Rep: Pyr... 89 9e-17
UniRef50_Q5C2V0 Cluster: Pyruvate kinase; n=1; Schistosoma japon... 89 9e-17
UniRef50_UPI0000DA20CA Cluster: PREDICTED: similar to Pyruvate k... 89 1e-16
UniRef50_Q9RR62 Cluster: Pyruvate kinase; n=5; Bacteria|Rep: Pyr... 88 2e-16
UniRef50_Q56301 Cluster: Pyruvate kinase; n=5; Thermococcaceae|R... 88 2e-16
UniRef50_Q6A9P1 Cluster: Pyruvate kinase; n=4; Actinomycetales|R... 88 2e-16
UniRef50_Q6YQT6 Cluster: Pyruvate kinase; n=6; Candidatus Phytop... 87 3e-16
UniRef50_Q1IJ65 Cluster: Pyruvate kinase; n=6; Bacteria|Rep: Pyr... 87 3e-16
UniRef50_Q40546 Cluster: Pyruvate kinase isozyme G, chloroplast ... 87 3e-16
UniRef50_Q81N35 Cluster: Pyruvate kinase; n=11; Bacillus cereus ... 87 5e-16
UniRef50_A4MK73 Cluster: Pyruvate kinase; n=1; Petrotoga mobilis... 86 8e-16
UniRef50_Q9VFG4 Cluster: Pyruvate kinase; n=3; Sophophora|Rep: P... 85 1e-15
UniRef50_A1BQT0 Cluster: Pyruvate kinase; n=2; Eukaryota|Rep: Py... 85 1e-15
UniRef50_Q82XE9 Cluster: Pyruvate kinase family; n=130; Proteoba... 85 2e-15
UniRef50_Q8YTZ8 Cluster: Pyruvate kinase; n=3; Nostocaceae|Rep: ... 84 2e-15
UniRef50_Q56XD5 Cluster: Pyruvate kinase; n=14; Magnoliophyta|Re... 84 2e-15
UniRef50_Q6MAN9 Cluster: Pyruvate kinase; n=1; Candidatus Protoc... 84 3e-15
UniRef50_O06134 Cluster: Pyruvate kinase; n=29; Bacteria|Rep: Py... 83 4e-15
UniRef50_Q40545 Cluster: Pyruvate kinase isozyme A, chloroplast ... 83 4e-15
UniRef50_Q8F253 Cluster: Pyruvate kinase; n=4; Leptospira|Rep: P... 83 6e-15
UniRef50_Q8SQP0 Cluster: Pyruvate kinase; n=1; Encephalitozoon c... 83 6e-15
UniRef50_Q4YDL9 Cluster: Putative uncharacterized protein; n=1; ... 82 1e-14
UniRef50_Q5IX04 Cluster: Pyruvate kinase; n=1; Prototheca wicker... 81 2e-14
UniRef50_Q44473 Cluster: Pyruvate kinase; n=4; Proteobacteria|Re... 80 4e-14
UniRef50_UPI0000D56D72 Cluster: PREDICTED: similar to CG7070-PB,... 80 5e-14
UniRef50_Q6KHW9 Cluster: Pyruvate kinase; n=3; Mycoplasma|Rep: P... 80 5e-14
UniRef50_Q2JLA2 Cluster: Pyruvate kinase; n=2; Synechococcus|Rep... 80 5e-14
UniRef50_Q2I6K6 Cluster: Pyruvate kinase; n=1; uncultured delta ... 80 5e-14
UniRef50_A4APL1 Cluster: Pyruvate kinase; n=15; Bacteroidetes|Re... 79 9e-14
UniRef50_A1WED1 Cluster: Pyruvate kinase; n=1; Verminephrobacter... 79 1e-13
UniRef50_A0L7K0 Cluster: Pyruvate kinase; n=1; Magnetococcus sp.... 78 2e-13
UniRef50_P73534 Cluster: Pyruvate kinase 2; n=37; Bacteria|Rep: ... 78 2e-13
UniRef50_A0QNT2 Cluster: Pyruvate kinase; n=1; Mycobacterium sme... 78 2e-13
UniRef50_Q9WY51 Cluster: Pyruvate kinase; n=3; Thermotogaceae|Re... 78 2e-13
UniRef50_Q6AII5 Cluster: Pyruvate kinase; n=1; Desulfotalea psyc... 77 3e-13
UniRef50_Q8ZNW0 Cluster: Pyruvate kinase II; n=173; Proteobacter... 77 5e-13
UniRef50_Q8G5M1 Cluster: Pyruvate kinase; n=23; Actinobacteridae... 76 7e-13
UniRef50_A6FYT4 Cluster: Pyruvate kinase; n=1; Plesiocystis paci... 76 9e-13
UniRef50_A6DH47 Cluster: Pyruvate kinase; n=1; Lentisphaera aran... 76 9e-13
UniRef50_Q94KE3 Cluster: Pyruvate kinase; n=25; Magnoliophyta|Re... 76 9e-13
UniRef50_A7D456 Cluster: Pyruvate kinase; n=2; Halobacteriaceae|... 75 1e-12
UniRef50_Q5V4I8 Cluster: Pyruvate kinase; n=4; Halobacteriaceae|... 75 2e-12
UniRef50_A0L5K6 Cluster: Pyruvate kinase; n=5; Proteobacteria|Re... 74 3e-12
UniRef50_Q7UF82 Cluster: Pyruvate kinase; n=1; Pirellula sp.|Rep... 73 5e-12
UniRef50_A6Q7D7 Cluster: Pyruvate kinase; n=19; cellular organis... 73 5e-12
UniRef50_Q0C0E8 Cluster: Pyruvate kinase; n=1; Hyphomonas neptun... 73 6e-12
UniRef50_A6Q5W9 Cluster: Pyruvate kinase; n=2; Epsilonproteobact... 71 2e-11
UniRef50_A7CAK5 Cluster: Pyruvate kinase; n=3; Ralstonia pickett... 71 3e-11
UniRef50_Q2TSX0 Cluster: Pyruvate kinase; n=2; cellular organism... 71 3e-11
UniRef50_Q8IJ37 Cluster: Pyruvate kinase; n=7; Plasmodium|Rep: P... 71 3e-11
UniRef50_Q7QVW2 Cluster: Pyruvate kinase; n=1; Giardia lamblia A... 70 4e-11
UniRef50_Q63P20 Cluster: Pyruvate kinase; n=74; Proteobacteria|R... 70 6e-11
UniRef50_A6C474 Cluster: Pyruvate kinase; n=1; Planctomyces mari... 69 1e-10
UniRef50_Q2FMN4 Cluster: Pyruvate kinase; n=1; Methanospirillum ... 69 1e-10
UniRef50_O05118 Cluster: Pyruvate kinase; n=44; Proteobacteria|R... 69 1e-10
UniRef50_Q6F1U1 Cluster: Pyruvate kinase; n=10; Mollicutes|Rep: ... 68 2e-10
UniRef50_Q9YEU2 Cluster: Pyruvate kinase; n=1; Aeropyrum pernix|... 67 3e-10
UniRef50_A1IEN3 Cluster: Pyruvate kinase; n=1; Candidatus Desulf... 67 4e-10
UniRef50_P78031 Cluster: Pyruvate kinase; n=6; Mycoplasma|Rep: P... 67 4e-10
UniRef50_A7QH42 Cluster: Chromosome chr3 scaffold_95, whole geno... 66 5e-10
UniRef50_A6LH43 Cluster: Pyruvate kinase; n=2; Parabacteroides|R... 66 7e-10
UniRef50_Q5ZZ75 Cluster: Pyruvate kinase II; n=4; Legionella pne... 64 2e-09
UniRef50_Q0AHE3 Cluster: Pyruvate kinase; n=2; Nitrosomonadaceae... 64 2e-09
UniRef50_P19680 Cluster: Pyruvate kinase; n=1; Spiroplasma citri... 64 3e-09
UniRef50_Q8EWX2 Cluster: Pyruvate kinase; n=1; Mycoplasma penetr... 63 5e-09
UniRef50_Q7P1G4 Cluster: Pyruvate kinase; n=4; Bacteria|Rep: Pyr... 63 5e-09
UniRef50_Q9PF54 Cluster: Pyruvate kinase; n=11; Xanthomonadaceae... 63 7e-09
UniRef50_A3DMY9 Cluster: Pyruvate kinase; n=1; Staphylothermus m... 63 7e-09
UniRef50_Q1ZJ78 Cluster: Pyruvate kinase; n=1; Psychromonas sp. ... 62 1e-08
UniRef50_Q0PQH4 Cluster: Pyruvate kinase; n=1; Endoriftia persep... 62 2e-08
UniRef50_A7APT5 Cluster: Pyruvate kinase family protein; n=1; Ba... 60 3e-08
UniRef50_Q1MPC8 Cluster: Pyruvate kinase; n=4; Desulfovibrionace... 59 8e-08
UniRef50_Q4N603 Cluster: Pyruvate kinase; n=2; Theileria|Rep: Py... 59 8e-08
UniRef50_A3ALA5 Cluster: Pyruvate kinase; n=3; Oryza sativa|Rep:... 59 1e-07
UniRef50_Q64MR8 Cluster: Pyruvate kinase; n=6; Bacteroides|Rep: ... 58 2e-07
UniRef50_A2BLH1 Cluster: Pyruvate kinase; n=1; Hyperthermus buty... 58 2e-07
UniRef50_Q07637 Cluster: Pyruvate kinase; n=44; Streptococcaceae... 58 2e-07
UniRef50_O51323 Cluster: Pyruvate kinase; n=5; cellular organism... 58 2e-07
UniRef50_P32044 Cluster: Pyruvate kinase; n=2; Thermoplasma|Rep:... 57 3e-07
UniRef50_Q6L281 Cluster: Pyruvate kinase; n=2; Thermoplasmatales... 57 4e-07
UniRef50_UPI00006CE5D4 Cluster: pyruvate kinase family protein; ... 45 1e-06
UniRef50_A7PC98 Cluster: Chromosome chr2 scaffold_11, whole geno... 55 1e-06
UniRef50_A3ZTM3 Cluster: Pyruvate kinase; n=1; Blastopirellula m... 54 2e-06
UniRef50_A5JEK8 Cluster: Pyruvate kinase; n=1; Nosema bombycis|R... 54 3e-06
UniRef50_A7QTW5 Cluster: Chromosome undetermined scaffold_171, w... 50 4e-05
UniRef50_A1RX09 Cluster: Pyruvate kinase; n=1; Thermofilum pende... 48 2e-04
UniRef50_Q22CT0 Cluster: Pyruvate kinase, barrel domain containi... 46 6e-04
UniRef50_Q8MR79 Cluster: Pyruvate kinase; n=3; Sophophora|Rep: P... 46 8e-04
UniRef50_Q2JJ60 Cluster: Pyruvate kinase; n=5; Bacteria|Rep: Pyr... 46 0.001
UniRef50_P46614 Cluster: Pyruvate kinase; n=1; Candida albicans|... 45 0.001
UniRef50_A3PTF7 Cluster: Pyruvate kinase; n=5; Mycobacterium|Rep... 45 0.002
UniRef50_A6LTB0 Cluster: Pyruvate kinase; n=1; Clostridium beije... 44 0.003
UniRef50_Q7NJ33 Cluster: Pyruvate kinase; n=1; Gloeobacter viola... 44 0.004
UniRef50_A4ARB8 Cluster: Pyruvate kinase; n=1; Flavobacteriales ... 44 0.004
UniRef50_A6PU80 Cluster: Pyruvate kinase; n=1; Victivallis vaden... 43 0.007
UniRef50_Q5KVI2 Cluster: Pyruvate kinase; n=2; Geobacillus|Rep: ... 42 0.013
UniRef50_A1U5Q4 Cluster: Pyruvate kinase; n=2; Marinobacter aqua... 42 0.017
UniRef50_Q9PQV7 Cluster: Pyruvate kinase; n=1; Ureaplasma parvum... 41 0.023
UniRef50_Q4IUP8 Cluster: Pyruvate kinase; n=1; Azotobacter vinel... 41 0.030
UniRef50_A4VPY3 Cluster: Pyruvate kinase; n=1; Pseudomonas stutz... 40 0.053
UniRef50_Q97ZD7 Cluster: Pyruvate kinase; n=4; Sulfolobaceae|Rep... 40 0.053
UniRef50_UPI00006CB055 Cluster: hypothetical protein TTHERM_0023... 37 0.37
UniRef50_A0NLM6 Cluster: Pyruvate kinase; n=2; Alphaproteobacter... 37 0.37
UniRef50_Q9M3B6 Cluster: Pyruvate kinase; n=1; Arabidopsis thali... 37 0.37
UniRef50_Q9VVH0 Cluster: CG12229-PA; n=2; Sophophora|Rep: CG1222... 36 0.86
UniRef50_A2STG1 Cluster: Putative anti-sigma regulatory factor, ... 35 1.5
UniRef50_Q4CYW8 Cluster: Putative uncharacterized protein; n=3; ... 35 2.0
UniRef50_Q9V2V8 Cluster: Pyruvate kinase; n=1; Thermoproteus ten... 35 2.0
UniRef50_A5NL17 Cluster: ATP-dependent Clp protease, ATP-binding... 34 2.6
UniRef50_Q8EYH8 Cluster: MutS-like mismatch repair protein, ATPa... 33 4.6
UniRef50_Q8DLH6 Cluster: Pyruvate kinase; n=2; Synechococcus|Rep... 33 4.6
UniRef50_Q2AHN9 Cluster: Radical SAM; n=1; Halothermothrix oreni... 33 4.6
UniRef50_Q1DYT2 Cluster: Putative uncharacterized protein; n=1; ... 33 6.0
>UniRef50_UPI0000D5551D Cluster: PREDICTED: similar to Pyruvate
kinase (PK); n=1; Tribolium castaneum|Rep: PREDICTED:
similar to Pyruvate kinase (PK) - Tribolium castaneum
Length = 557
Score = 205 bits (501), Expect = 6e-52
Identities = 95/161 (59%), Positives = 122/161 (75%)
Frame = +3
Query: 171 SQLQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYH 350
+QL H LDI S +RL+GIICT+GP++ +V LE+M+E GMN+AR+ SHG+ E H
Sbjct: 32 TQLDHNSLLDIQSHPPQVRLTGIICTLGPSTTDVETLERMIEAGMNIARLTLSHGTQEMH 91
Query: 351 AETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTT 530
E I+N R A ++YS +LG + L++ALD KGPE+RTG +EGG +AEVELKKGE IKLTT
Sbjct: 92 TELIQNVRTAVENYSKRLGVMYPLSLALDIKGPEVRTGYMEGGIAAEVELKKGEQIKLTT 151
Query: 531 SSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIIC 653
Y EKG++ IYVDY NI VV+PGNRIF+DDGLIS+IC
Sbjct: 152 DKAYLEKGSSSVIYVDYDNIQKVVQPGNRIFLDDGLISLIC 192
>UniRef50_Q4SVB7 Cluster: Pyruvate kinase; n=1; Tetraodon
nigroviridis|Rep: Pyruvate kinase - Tetraodon
nigroviridis (Green puffer)
Length = 569
Score = 200 bits (488), Expect = 2e-50
Identities = 94/157 (59%), Positives = 123/157 (78%)
Frame = +3
Query: 177 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 356
L+HMC LDIDS + R +GIICTIGPASR+V +L++M+++GMN+AR+NFSHG+HEYHAE
Sbjct: 25 LEHMCLLDIDSAPTTARNTGIICTIGPASRSVGMLKEMIKSGMNIARLNFSHGTHEYHAE 84
Query: 357 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS 536
TI+N REA +S+ + IALDTKGPEIRTGL+ G G+AEVELKKG IK+T
Sbjct: 85 TIKNVREACESFEPGSIQYRPIGIALDTKGPEIRTGLIHGSGTAEVELKKGNVIKITLDD 144
Query: 537 DYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISI 647
Y EK + + +++DYKNIT VV G++I+IDDGLIS+
Sbjct: 145 AYVEKCSEEILWLDYKNITKVVDVGSKIYIDDGLISL 181
>UniRef50_P30613 Cluster: Pyruvate kinase isozymes R/L; n=167;
Fungi/Metazoa group|Rep: Pyruvate kinase isozymes R/L -
Homo sapiens (Human)
Length = 574
Score = 192 bits (468), Expect = 6e-48
Identities = 94/163 (57%), Positives = 124/163 (76%), Gaps = 3/163 (1%)
Frame = +3
Query: 177 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 356
L+H+C LDIDS+ R + II TIGPASR+V L++M++ GMN+AR+NFSHGSHEYHAE
Sbjct: 70 LEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAE 129
Query: 357 TIRNCREAEKSYSAKLGSPFS---LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLT 527
+I N REA +S++ GSP S +AIALDTKGPEIRTG+L+GG +EVEL KG + +T
Sbjct: 130 SIANVREAVESFA---GSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVT 186
Query: 528 TSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQ 656
++ +GNA+T++VDY NI VV G RI+IDDGLIS++ Q
Sbjct: 187 VDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQ 229
>UniRef50_Q27686 Cluster: Pyruvate kinase; n=16; Kinetoplastida|Rep:
Pyruvate kinase - Leishmania mexicana
Length = 499
Score = 153 bits (372), Expect = 3e-36
Identities = 78/162 (48%), Positives = 111/162 (68%)
Frame = +3
Query: 171 SQLQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYH 350
SQL H L I + R + IICTIGP++++V L+ ++++GM+VARMNFSHGSHEYH
Sbjct: 2 SQLAHNLTLSIFDPVANYRAARIICTIGPSTQSVEALKGLIQSGMSVARMNFSHGSHEYH 61
Query: 351 AETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTT 530
TI N R+A +A+LG ++AIALDTKGPEIRTG GG + +++G T +TT
Sbjct: 62 QTTINNVRQA----AAELG--VNIAIALDTKGPEIRTGQFVGG---DAVMERGATCYVTT 112
Query: 531 SSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQ 656
+ +KG D Y+DY+N++ VV+PGN I+IDDG++ + Q
Sbjct: 113 DPAFADKGTKDKFYIDYQNLSKVVRPGNYIYIDDGILILQVQ 154
>UniRef50_Q9VD23 Cluster: Pyruvate kinase; n=5; Coelomata|Rep:
Pyruvate kinase - Drosophila melanogaster (Fruit fly)
Length = 744
Score = 147 bits (356), Expect = 2e-34
Identities = 68/117 (58%), Positives = 86/117 (73%), Gaps = 1/117 (0%)
Frame = +3
Query: 303 MNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGG 482
M V RMNFSHGSHEYH +TI+ R+A Y + G P +LAIALDTKGPEIRTG L GG
Sbjct: 1 MRVVRMNFSHGSHEYHCQTIQAARKAIAMYVEQTGLPRTLAIALDTKGPEIRTGKLAGGN 60
Query: 483 S-AEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISII 650
AE+ELK G+ + L+T + +K N D IYVDY+ + +VKPGNR+F+DDGLI++I
Sbjct: 61 DRAEIELKTGDKVTLSTKKEMADKSNKDNIYVDYQRLPQLVKPGNRVFVDDGLIALI 117
>UniRef50_Q9VQH0 Cluster: Pyruvate kinase; n=3; Sophophora|Rep:
Pyruvate kinase - Drosophila melanogaster (Fruit fly)
Length = 554
Score = 145 bits (352), Expect = 7e-34
Identities = 70/163 (42%), Positives = 106/163 (65%)
Frame = +3
Query: 147 KPTVANVGSQLQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNF 326
K + +QL H+C LD+ ++S+ RL +I TI +SRN + M+ G+N+ R+NF
Sbjct: 6 KSVLKEGSTQLSHICELDLAQQASHQRLVSLIATISVSSRNADTIYTMIMRGVNIFRLNF 65
Query: 327 SHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKK 506
SH SHE H++TI EA + + G ++AIA DT+GP+IRTGLL+G +V L+
Sbjct: 66 SHESHEMHSKTIELINEALERIHKETGQIRTVAIAADTRGPQIRTGLLDG----DVFLRS 121
Query: 507 GETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDG 635
G+ ++L+ + D +KGN + +YVDY NI N+ K G+R+FIDDG
Sbjct: 122 GDNLRLSINRDLYDKGNKEAVYVDYPNIINLTKTGDRLFIDDG 164
>UniRef50_Q7RVA8 Cluster: Pyruvate kinase; n=11; Ascomycota|Rep:
Pyruvate kinase - Neurospora crassa
Length = 527
Score = 136 bits (328), Expect = 6e-31
Identities = 67/162 (41%), Positives = 104/162 (64%), Gaps = 1/162 (0%)
Frame = +3
Query: 162 NVGSQLQHMCGLDIDSKSSY-IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGS 338
++G ++Q + L+ + + + R + IICTIGP + +V + K+ + G+NV RMNFSHGS
Sbjct: 10 SLGGKIQWLAQLNTEFQPAREFRRTSIICTIGPKTNSVEAINKLRDAGLNVVRMNFSHGS 69
Query: 339 HEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETI 518
+EYH I N R+AEK + G P +AIALDTKGPEIRTG + ++ + G +
Sbjct: 70 YEYHQSVIDNARQAEKVHP---GRP--IAIALDTKGPEIRTGNTK--NDEDIPISAGTIL 122
Query: 519 KLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLIS 644
+TT Y+++ + +YVDY NIT V+ PG I++DDG+++
Sbjct: 123 NITTDEKYKDECTIEHMYVDYVNITKVIAPGRIIYVDDGVLA 164
>UniRef50_Q42806 Cluster: Pyruvate kinase, cytosolic isozyme; n=62;
Eukaryota|Rep: Pyruvate kinase, cytosolic isozyme -
Glycine max (Soybean)
Length = 511
Score = 127 bits (306), Expect = 3e-28
Identities = 63/137 (45%), Positives = 90/137 (65%)
Frame = +3
Query: 237 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 416
I+CT+GPASR+V + EK++ GMNVAR NFSHG+H+YH ET+ N + +A +
Sbjct: 25 IVCTLGPASRSVEMTEKLLRAGMNVARFNFSHGTHDYHQETLNNLK------TAMHNTGI 78
Query: 417 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 596
A+ LDTKGPEIRTG L+ G ++LK+G+ + +TT DY KG+ + I + YK +
Sbjct: 79 LCAVMLDTKGPEIRTGFLKDG--KPIQLKEGQEVTITT--DYDIKGDPEMISMSYKKLPV 134
Query: 597 VVKPGNRIFIDDGLISI 647
+KPGN I DG I++
Sbjct: 135 HLKPGNTILCSDGTITL 151
>UniRef50_Q9M057 Cluster: Pyruvate kinase; n=11; Magnoliophyta|Rep:
Pyruvate kinase - Arabidopsis thaliana (Mouse-ear cress)
Length = 510
Score = 124 bits (299), Expect = 2e-27
Identities = 64/137 (46%), Positives = 90/137 (65%)
Frame = +3
Query: 237 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 416
IICT+GP SR+V ++EK+++ GMNVAR NFSHGSH YH ET+ N R A + +
Sbjct: 20 IICTLGPVSRSVEMIEKLLKAGMNVARFNFSHGSHSYHQETLDNLRTAMDN------TGI 73
Query: 417 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 596
A+ LDTKGPEIRTG L+ G ++L +G+ ++T S DY +G+++ I + YK +
Sbjct: 74 LSAVMLDTKGPEIRTGFLKEG--KPIQLNQGQ--EITISIDYMIEGDSNVISMSYKKLAE 129
Query: 597 VVKPGNRIFIDDGLISI 647
VKPG+ I DG IS+
Sbjct: 130 DVKPGDVILCSDGTISL 146
>UniRef50_P80885 Cluster: Pyruvate kinase; n=161; Bacteria|Rep:
Pyruvate kinase - Bacillus subtilis
Length = 585
Score = 120 bits (290), Expect = 2e-26
Identities = 68/142 (47%), Positives = 93/142 (65%)
Frame = +3
Query: 222 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 401
+R + I+CTIGPAS ++ +L K+ME+GMNVAR+NFSHG E H I+N REA K K
Sbjct: 1 MRKTKIVCTIGPASESIEMLTKLMESGMNVARLNFSHGDFEEHGARIKNIREASK----K 56
Query: 402 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 581
LG ++ I LDTKGPEIRT +E GG +EL+ G+ +L S D + G D I V Y
Sbjct: 57 LGK--NVGILLDTKGPEIRTHTMENGG---IELETGK--ELIISMD-EVVGTTDKISVTY 108
Query: 582 KNITNVVKPGNRIFIDDGLISI 647
+ + + V+ G+ I +DDGLI +
Sbjct: 109 EGLVHDVEQGSTILLDDGLIGL 130
>UniRef50_O44006 Cluster: Pyruvate kinase; n=10; cellular
organisms|Rep: Pyruvate kinase - Eimeria tenella
Length = 531
Score = 118 bits (283), Expect = 2e-25
Identities = 60/137 (43%), Positives = 85/137 (62%)
Frame = +3
Query: 237 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 416
I+CT+GP+ +V + ++++ GMNV R+NFSHG HE H ++N +EA K K
Sbjct: 60 IVCTMGPSCWDVDKMVQLIDAGMNVCRLNFSHGDHEAHGRVVKNLQEALKQRPGK----- 114
Query: 417 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 596
+A+ LDTKGPEIRTG+LE G +EL G+ +K+ T DY GN I Y+ + +
Sbjct: 115 RVALLLDTKGPEIRTGMLE--GDKPIELHAGDMLKIVT--DYSFVGNKSCIACSYEKLPS 170
Query: 597 VVKPGNRIFIDDGLISI 647
VKPGN I I DG +S+
Sbjct: 171 SVKPGNTILIADGSLSV 187
>UniRef50_P52489 Cluster: Pyruvate kinase 2; n=33; Dikarya|Rep:
Pyruvate kinase 2 - Saccharomyces cerevisiae (Baker's
yeast)
Length = 506
Score = 113 bits (271), Expect = 5e-24
Identities = 59/158 (37%), Positives = 92/158 (58%)
Frame = +3
Query: 171 SQLQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYH 350
S+LQ + L I + +R + II TIGP + + + + + G+N+ R+NFSHGS+E+H
Sbjct: 4 SRLQRLANLKIGTPQQ-LRRTSIIGTIGPKTNSCEAITALRKAGLNIIRLNFSHGSYEFH 62
Query: 351 AETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTT 530
I N ++E+ + G P LAIALDTKGPEIRTG ++ + + TT
Sbjct: 63 QSVIENAVKSEQQFP---GRP--LAIALDTKGPEIRTG--RTLNDQDLYIPVDHQMIFTT 115
Query: 531 SSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLIS 644
+ + N +Y+DY N+T V+ PG I++DDG++S
Sbjct: 116 DASFANTSNDKIMYIDYANLTKVIVPGRFIYVDDGILS 153
>UniRef50_Q2TSW8 Cluster: Pyruvate kinase; n=4; stramenopiles|Rep:
Pyruvate kinase - Phaeodactylum tricornutum
Length = 543
Score = 112 bits (270), Expect = 6e-24
Identities = 63/137 (45%), Positives = 82/137 (59%)
Frame = +3
Query: 225 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 404
R + I+CTIGPA NV LE ++E+GMNVAR NFSHG H H + R+A ++
Sbjct: 31 RRTKIVCTIGPACWNVDQLEILIESGMNVARFNFSHGDHAGHGAVLERVRQAAQNKGR-- 88
Query: 405 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 584
++AI LDTKGPEIRTG G S ++EL KGETI LT SDY+ KG+ + Y
Sbjct: 89 ----NIAILLDTKGPEIRTGFFANGAS-KIELVKGETIVLT--SDYKFKGDQHKLACSYP 141
Query: 585 NITNVVKPGNRIFIDDG 635
+ V G +I + DG
Sbjct: 142 ALAQSVTQGQQILVADG 158
>UniRef50_Q4U977 Cluster: Pyruvate kinase, putative; n=3;
Piroplasmida|Rep: Pyruvate kinase, putative - Theileria
annulata
Length = 513
Score = 111 bits (267), Expect = 1e-23
Identities = 59/136 (43%), Positives = 84/136 (61%)
Frame = +3
Query: 237 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 416
I+CT+GPA NV + +M+++GMN+ R NFSHG+HE H +T+ +EA KS
Sbjct: 42 IVCTMGPACGNVETIIQMVKSGMNICRFNFSHGNHETHTKTLNLVKEALKSVPEA----- 96
Query: 417 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 596
++ + LDTKGPEIRTG L+ + L++G T+K+TT DY +G+ I YK +
Sbjct: 97 NIGLMLDTKGPEIRTGFLK--NHTPITLEEGSTLKITT--DYTIEGDETIISCSYKKLPQ 152
Query: 597 VVKPGNRIFIDDGLIS 644
VK GN I I DG +S
Sbjct: 153 SVKVGNIILIADGSLS 168
>UniRef50_P77983 Cluster: Pyruvate kinase I; n=29; Bacteria|Rep:
Pyruvate kinase I - Salmonella typhimurium
Length = 470
Score = 111 bits (267), Expect = 1e-23
Identities = 61/137 (44%), Positives = 83/137 (60%)
Frame = +3
Query: 237 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 416
I+CTIGP + + +L KM++ GMNV R+NFSHG + H + I+N R + +K G
Sbjct: 6 IVCTIGPKTESEEMLSKMLDAGMNVMRLNFSHGDYAEHGQRIQNLR----NVMSKTGK-- 59
Query: 417 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 596
AI LDTKGPEIRT LEGG +V LK G+T TT D GN + + V Y+ T+
Sbjct: 60 KAAILLDTKGPEIRTIKLEGGN--DVSLKAGQTFTFTT--DKSVVGNNEIVAVTYEGFTS 115
Query: 597 VVKPGNRIFIDDGLISI 647
+ GN + +DDGLI +
Sbjct: 116 DLSVGNTVLVDDGLIGM 132
>UniRef50_Q8EX62 Cluster: Pyruvate kinase; n=5; Bacteria|Rep:
Pyruvate kinase - Leptospira interrogans
Length = 486
Score = 110 bits (265), Expect = 2e-23
Identities = 61/150 (40%), Positives = 95/150 (63%)
Frame = +3
Query: 207 SKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEK 386
S+SS R + IICTIGPA+ + +++ + E GMNVAR+N SHG+H++H IRN + K
Sbjct: 3 SESSVFRKTKIICTIGPATSDKKMIQALAEAGMNVARLNMSHGNHDFHRSIIRNIKSLNK 62
Query: 387 SYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADT 566
L +P +AI LDT+GPEIRTG L+ ++LK GET T E+ +
Sbjct: 63 DV---LKNP--IAILLDTQGPEIRTGDLQ---VDHLDLKVGET--FTFHIIPGEESEEQS 112
Query: 567 IYVDYKNITNVVKPGNRIFIDDGLISIICQ 656
++V+YK+I +K G+ + +D+GLI+++ +
Sbjct: 113 VFVNYKDIVKDLKVGDPVTVDNGLINLVVE 142
>UniRef50_Q090R5 Cluster: Pyruvate kinase; n=1; Stigmatella
aurantiaca DW4/3-1|Rep: Pyruvate kinase - Stigmatella
aurantiaca DW4/3-1
Length = 515
Score = 109 bits (262), Expect = 6e-23
Identities = 62/142 (43%), Positives = 87/142 (61%)
Frame = +3
Query: 222 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 401
+R + I+CT+GPAS++ +LE ++E GM+VAR+NFSHGSHE HAE I R A S K
Sbjct: 10 MRRAKIVCTLGPASQSQDMLEALIEAGMDVARLNFSHGSHEQHAENIAKLRAA----SLK 65
Query: 402 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 581
L ++ I D +GP+IRTG G + LK+G +TT D KGN D + Y
Sbjct: 66 LRK--AVGILGDLQGPKIRTGRFITGSTV---LKEGAIFSITT--DESVKGNDDIVSTTY 118
Query: 582 KNITNVVKPGNRIFIDDGLISI 647
++ V PG+RI +DDGL+ +
Sbjct: 119 AHLAADVNPGDRILLDDGLLEL 140
>UniRef50_Q1FK29 Cluster: Pyruvate kinase; n=4; Clostridiales|Rep:
Pyruvate kinase - Clostridium phytofermentans ISDg
Length = 580
Score = 109 bits (261), Expect = 8e-23
Identities = 62/142 (43%), Positives = 85/142 (59%)
Frame = +3
Query: 222 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 401
+R + I+CT+GPA+ + AVL ++M GM+VAR NFSHG +E H R SA+
Sbjct: 1 MRKTKIVCTLGPATEDDAVLRQLMIEGMDVARFNFSHGDYEQHTRNYERIRR----LSAE 56
Query: 402 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 581
L P +A LDTKGPEIR G E G ++ELKKG+ LTT+ G+ + + Y
Sbjct: 57 LKLP--IATLLDTKGPEIRIGTFENG---KIELKKGQIFTLTTNDIV---GDETQVSITY 108
Query: 582 KNITNVVKPGNRIFIDDGLISI 647
KN+ +K G +I IDDGLI +
Sbjct: 109 KNLIRDIKNGVKILIDDGLIEL 130
>UniRef50_Q22Z06 Cluster: Pyruvate kinase family protein; n=3;
Oligohymenophorea|Rep: Pyruvate kinase family protein -
Tetrahymena thermophila SB210
Length = 505
Score = 106 bits (254), Expect = 5e-22
Identities = 57/142 (40%), Positives = 83/142 (58%)
Frame = +3
Query: 225 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 404
R + I+CTIGP+ + L +++E GMNVAR+NFSHG H H ET+R +EA K+
Sbjct: 22 RKTKIVCTIGPSCWDHDNLVQLLENGMNVARLNFSHGDHAGHGETVRRLKEAFKA----- 76
Query: 405 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 584
A+ LDTKGPEIRTGL++ + L G+ +++TT DY G+ + YK
Sbjct: 77 RKNIQCALMLDTKGPEIRTGLVKDQTKKLINLVAGQELEITT--DYSVLGDEKVLACSYK 134
Query: 585 NITNVVKPGNRIFIDDGLISII 650
++ VK G ++ I DG + I
Sbjct: 135 SLPKSVKVGGQVLIADGTLVCI 156
>UniRef50_A4E9R2 Cluster: Pyruvate kinase; n=1; Collinsella
aerofaciens ATCC 25986|Rep: Pyruvate kinase -
Collinsella aerofaciens ATCC 25986
Length = 486
Score = 104 bits (249), Expect = 2e-21
Identities = 61/140 (43%), Positives = 87/140 (62%), Gaps = 3/140 (2%)
Frame = +3
Query: 237 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 416
I+CT+GPA + + +M++ GMNVAR NFSHGS++ H I R K +LG P
Sbjct: 7 IVCTMGPACDSDETIREMIKAGMNVARFNFSHGSYDEHHGRIERVRRISK----ELGLP- 61
Query: 417 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLT---TSSDYQEKGNADTIYVDYKN 587
+ I LDTKGPE+RTGLL G +V +K G+ I +T TS D+ G A+ I +DY
Sbjct: 62 -VGILLDTKGPEVRTGLLVDG--KKVAVKTGDKIVVTAQPTSEDFH--GTAEHISLDYLA 116
Query: 588 ITNVVKPGNRIFIDDGLISI 647
+ + V+ G+ I IDDGL+++
Sbjct: 117 LPSEVEKGSLILIDDGLVAL 136
>UniRef50_A7HIL5 Cluster: Pyruvate kinase; n=9; Bacteria|Rep:
Pyruvate kinase - Anaeromyxobacter sp. Fw109-5
Length = 491
Score = 101 bits (242), Expect = 2e-20
Identities = 56/142 (39%), Positives = 88/142 (61%)
Frame = +3
Query: 222 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 401
+R + I+ T+GPAS + VL++M+ G++VAR+NFSHG HE HA+ + R A S
Sbjct: 4 MRRAKIVATLGPASSDPDVLQRMLAAGVDVARLNFSHGRHEDHAQMLDRIRTA----SRH 59
Query: 402 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 581
LG ++A+ D +GP+IRTG L G V L+ G +L ++D + KG+A + Y
Sbjct: 60 LGR--AVAVLQDLQGPKIRTGPLAAGREG-VRLEAG--AELVIATDAEVKGDAKLVSTTY 114
Query: 582 KNITNVVKPGNRIFIDDGLISI 647
++ V+PG+R+ +DDGLI +
Sbjct: 115 PHLAEDVRPGDRLLVDDGLIEL 136
>UniRef50_Q8TJ98 Cluster: Pyruvate kinase; n=2; Methanomicrobia|Rep:
Pyruvate kinase - Methanosarcina acetivorans
Length = 489
Score = 101 bits (241), Expect = 2e-20
Identities = 57/139 (41%), Positives = 79/139 (56%)
Frame = +3
Query: 237 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 416
I+CTIGPAS + VL K++ GMNVAR+NFSHG E H + IR R+ +
Sbjct: 22 IVCTIGPASFSEEVLRKLVLAGMNVARINFSHGDFESHGKVIRRVRKVAEELDR------ 75
Query: 417 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 596
++AI D GP+IR G L+ + L KG I LTT + G+ D I V+YK +
Sbjct: 76 TVAILADLPGPKIRVGKLK---KEPLMLHKGNRITLTTD---ETSGSEDRIPVNYKQLPE 129
Query: 597 VVKPGNRIFIDDGLISIIC 653
V PG+ I++ DG I ++C
Sbjct: 130 SVSPGSLIYLSDGFIQLLC 148
>UniRef50_Q6MLB5 Cluster: Pyruvate kinase; n=1; Bdellovibrio
bacteriovorus|Rep: Pyruvate kinase - Bdellovibrio
bacteriovorus
Length = 495
Score = 99 bits (238), Expect = 5e-20
Identities = 55/141 (39%), Positives = 82/141 (58%)
Frame = +3
Query: 225 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 404
R + I+ TIGPA+R+ LEK ++ GMNVAR+NFSHGSHE H + + + R+ K A
Sbjct: 5 RRAKIVATIGPATRDEKNLEKAIKAGMNVARLNFSHGSHEDHLKVVHSLRKLSKELQA-- 62
Query: 405 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 584
+AI D +GP+IR G E G +E+K GE + +TT+ + G + D++
Sbjct: 63 ----PVAILQDLQGPKIRVGKFENG---SIEIKPGEKLVVTTA---KVLGKPGLVPSDFQ 112
Query: 585 NITNVVKPGNRIFIDDGLISI 647
+ PG RI +DDGL+ +
Sbjct: 113 ELPLACVPGTRILLDDGLMEV 133
>UniRef50_Q2TSW6 Cluster: Pyruvate kinase; n=1; Achlya
bisexualis|Rep: Pyruvate kinase - Achlya bisexualis
(Water mold)
Length = 517
Score = 99 bits (238), Expect = 5e-20
Identities = 49/148 (33%), Positives = 84/148 (56%), Gaps = 1/148 (0%)
Frame = +3
Query: 207 SKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEK 386
SK+ ++ I+ T+GP S N +++ G+ + R+NFSH +++ + + R ++
Sbjct: 23 SKNDAFSMTKIVGTVGPVSENAKTTQELTNAGLKIMRINFSHATYDEAHLRMSHLRASKG 82
Query: 387 SYSAKLGSPFSL-AIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNAD 563
++ G F++ A+ LDT+GPEIR G ++ L KG+ I LTT Y+E D
Sbjct: 83 VHAKHTGKEFNVRAVLLDTQGPEIRGGAFP---EKKINLTKGDMITLTTDVQYKEASTKD 139
Query: 564 TIYVDYKNITNVVKPGNRIFIDDGLISI 647
+YV Y+ + VK G+ + +DDGLIS+
Sbjct: 140 MLYVTYEQLPATVKVGDTVLLDDGLISL 167
>UniRef50_Q8PYY4 Cluster: Pyruvate kinase; n=3;
Methanosarcinaceae|Rep: Pyruvate kinase - Methanosarcina
mazei (Methanosarcina frisia)
Length = 477
Score = 99 bits (238), Expect = 5e-20
Identities = 58/140 (41%), Positives = 80/140 (57%)
Frame = +3
Query: 237 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 416
I+CTIGPAS + ++ K+M GMNVAR+NFSHG E H+ +R R+ + +LG
Sbjct: 10 IVCTIGPASSSEEMIRKLMLAGMNVARINFSHGDFESHSRVVRIIRKV----ADELGR-- 63
Query: 417 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 596
++AI D GP+IR G LE V L KG I LT GN + I V YK +
Sbjct: 64 TIAILADLPGPKIRIGKLE---KEPVMLHKGNPITLTID---DTPGNEERIPVSYKQLPE 117
Query: 597 VVKPGNRIFIDDGLISIICQ 656
V PG+ I++ DG I ++C+
Sbjct: 118 SVTPGSLIYLSDGFIQLLCK 137
>UniRef50_Q9KUN0 Cluster: Pyruvate kinase; n=24; cellular
organisms|Rep: Pyruvate kinase - Vibrio cholerae
Length = 470
Score = 99.1 bits (236), Expect = 8e-20
Identities = 58/137 (42%), Positives = 77/137 (56%)
Frame = +3
Query: 237 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 416
I+CTIGP + +V L +++ GMNV R+NFSHG + H I N R+ + K
Sbjct: 6 IVCTIGPKTESVEKLTELVNAGMNVMRLNFSHGDYVEHGTRITNFRKV-MEVTGK----- 59
Query: 417 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 596
LAI LDTKGPEIRT LE G +V+L G+ TT D + GN + + V Y
Sbjct: 60 QLAILLDTKGPEIRTIKLENGD--DVDLVAGQEFTFTT--DTKVVGNKERVAVTYSGFAK 115
Query: 597 VVKPGNRIFIDDGLISI 647
+ GNRI +DDGLI +
Sbjct: 116 DLNVGNRILVDDGLIEM 132
>UniRef50_Q55863 Cluster: Pyruvate kinase 1; n=5; Cyanobacteria|Rep:
Pyruvate kinase 1 - Synechocystis sp. (strain PCC 6803)
Length = 483
Score = 97.9 bits (233), Expect = 2e-19
Identities = 55/137 (40%), Positives = 82/137 (59%)
Frame = +3
Query: 237 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 416
I+ TIGPAS +V V+ +M++ GMNVAR+NFSHGS+E HA +R R E+ ++ +P
Sbjct: 20 IVATIGPASSSVEVIRQMVDAGMNVARLNFSHGSYEDHATMVRLLRSVEQ----EMDTPI 75
Query: 417 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 596
+L D +GP+IR G L GG E +L++GE + L A + +DY ++
Sbjct: 76 TL--LQDLQGPKIRIGQLPGG---EKQLREGEKVSLVPVEIGDRHPGA--VGIDYPHLAT 128
Query: 597 VVKPGNRIFIDDGLISI 647
K G RI +DDGL+ +
Sbjct: 129 EAKVGERILLDDGLLEM 145
>UniRef50_Q04668 Cluster: Pyruvate kinase; n=2; Leishmania
braziliensis|Rep: Pyruvate kinase - Leishmania
braziliensis
Length = 91
Score = 97.5 bits (232), Expect = 2e-19
Identities = 54/99 (54%), Positives = 72/99 (72%), Gaps = 1/99 (1%)
Frame = +3
Query: 171 SQLQHMCGLDIDSKSSYIRLSG-IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEY 347
SQL H L I +R +G I+CTIGP++++V L+ ++++GM+VARMNFSHGSHEY
Sbjct: 2 SQLAHNLTLSIFEP---LRTTGTIVCTIGPSTQSVEALKGLIKSGMSVARMNFSHGSHEY 58
Query: 348 HAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTG 464
H TI N R+A +A+LG ++AIALDTKGPEIRTG
Sbjct: 59 HQTTINNVRQA----AAELG--VNIAIALDTKGPEIRTG 91
>UniRef50_UPI0000DB6F59 Cluster: PREDICTED: similar to Pyruvate
kinase CG7070-PB, isoform B; n=1; Apis mellifera|Rep:
PREDICTED: similar to Pyruvate kinase CG7070-PB, isoform
B - Apis mellifera
Length = 538
Score = 97.1 bits (231), Expect = 3e-19
Identities = 50/174 (28%), Positives = 94/174 (54%), Gaps = 4/174 (2%)
Frame = +3
Query: 144 EKPTVANVGSQLQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMN 323
E+ A ++L+H L+I+S RL+ I+ T+G + + + +M G N+ R+N
Sbjct: 12 EQIKAAYQNTRLEHNINLNINSSPKLARLTRIMVTLGRRNSHPEAVVSIMMAGANIVRLN 71
Query: 324 FSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSA--EVE 497
+H + ++H T+++ R+A + + L +A++ +GPEIR G G ++ +
Sbjct: 72 MAHETDKWHTATVQSVRKAGNTMYEFTSEIYPLGVAINLQGPEIRAGAFRGDKTSLGYAK 131
Query: 498 LKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDG--LISIIC 653
LK+G+ +KL T + G A+ +V Y N+ + + G+RI ID G L+ + C
Sbjct: 132 LKEGKMVKLVTQDIAKRAGRANCFWVSYPNLPKICQVGDRILIDRGAVLLQVTC 185
>UniRef50_Q2IHE2 Cluster: Pyruvate kinase; n=1; Anaeromyxobacter
dehalogenans 2CP-C|Rep: Pyruvate kinase -
Anaeromyxobacter dehalogenans (strain 2CP-C)
Length = 489
Score = 96.7 bits (230), Expect = 4e-19
Identities = 53/140 (37%), Positives = 86/140 (61%)
Frame = +3
Query: 222 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 401
+R + I+ T+GPAS VL +++E G++VAR+NFSHG HE HA + R A S
Sbjct: 1 MRRAKIVATLGPASGEPDVLARLLEQGVDVARLNFSHGRHEDHARMLDKIRAA----SRH 56
Query: 402 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 581
LG ++A+ D +GP+IRTG L+ G A V+++ G+ + +TT + G+A + Y
Sbjct: 57 LGK--AVAVLQDLQGPKIRTGPLK-AGKAGVQVEAGQELVITTEGEL--PGDAHLVSTTY 111
Query: 582 KNITNVVKPGNRIFIDDGLI 641
++ V+ G+R+ +DDGL+
Sbjct: 112 PHLAEDVRAGDRLLVDDGLL 131
>UniRef50_Q46078 Cluster: Pyruvate kinase; n=19; Actinobacteria
(class)|Rep: Pyruvate kinase - Corynebacterium
glutamicum (Brevibacterium flavum)
Length = 475
Score = 96.3 bits (229), Expect = 6e-19
Identities = 50/143 (34%), Positives = 79/143 (55%)
Frame = +3
Query: 225 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 404
R + I+CT+GPA + + +++E GM+VAR+NFSHG H H + + REA + +
Sbjct: 3 RRTKIVCTLGPAVASADGILRLVEDGMDVARLNFSHGDHPDHEQNYKWVREAAEKTGRAV 62
Query: 405 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 584
G I D +GP+IR G G + + GETI++T +G D + YK
Sbjct: 63 G------ILADLQGPKIRLGRFTDGATV---WENGETIRITVD---DVEGTHDRVSTTYK 110
Query: 585 NITNVVKPGNRIFIDDGLISIIC 653
N+ KPG+R+ +DDG + ++C
Sbjct: 111 NLAKDAKPGDRLLVDDGKVGLVC 133
>UniRef50_Q3JCE7 Cluster: Pyruvate kinase; n=1; Nitrosococcus oceani
ATCC 19707|Rep: Pyruvate kinase - Nitrosococcus oceani
(strain ATCC 19707 / NCIMB 11848)
Length = 492
Score = 95.5 bits (227), Expect = 1e-18
Identities = 56/141 (39%), Positives = 85/141 (60%)
Frame = +3
Query: 225 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 404
R I+CTIGPASR+ A+L KM+ +GMNVAR+NFSHG+HE H REA + +L
Sbjct: 24 RACRIVCTIGPASRSPAILRKMLLSGMNVARLNFSHGNHESHGRIACEIREA----AQRL 79
Query: 405 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 584
P +AI D +G ++R G ++ S + L++G+ I L + E ++ I +DY+
Sbjct: 80 MKP--VAILQDLQGHKVRVGKVQHPPS--LSLEEGQEILL----GHGETISSKRIGIDYQ 131
Query: 585 NITNVVKPGNRIFIDDGLISI 647
+I V PG ++F+DD I +
Sbjct: 132 DIIQYVTPGQKVFLDDASIEL 152
>UniRef50_Q2S3S2 Cluster: Pyruvate kinase; n=1; Salinibacter ruber
DSM 13855|Rep: Pyruvate kinase - Salinibacter ruber
(strain DSM 13855)
Length = 476
Score = 94.3 bits (224), Expect = 2e-18
Identities = 47/141 (33%), Positives = 82/141 (58%)
Frame = +3
Query: 225 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 404
R + I+CT+GPA+ + L +++ GM+VARMNFSHG+HE H E + RE ++
Sbjct: 3 RRTKIVCTLGPATTDPETLRRLVAAGMDVARMNFSHGTHEEHRERVETVREVAEAEGK-- 60
Query: 405 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 584
+ + D +GP+IR G ++ + V L +G+ ++++T D + + I++DY+
Sbjct: 61 ----GITVLQDLQGPKIRVGAVQ---NDSVMLAEGDEVRVST--DTPRESTNEHIFIDYE 111
Query: 585 NITNVVKPGNRIFIDDGLISI 647
+ + G RI IDDGL+ +
Sbjct: 112 ALARDAREGERILIDDGLLEL 132
>UniRef50_Q1K4D5 Cluster: Pyruvate kinase; n=1; Desulfuromonas
acetoxidans DSM 684|Rep: Pyruvate kinase -
Desulfuromonas acetoxidans DSM 684
Length = 474
Score = 93.1 bits (221), Expect = 5e-18
Identities = 55/142 (38%), Positives = 83/142 (58%)
Frame = +3
Query: 222 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 401
+R + I+CT+GPAS + A LE+M+ +GMNVAR+NFSHG H+ H + I R K +
Sbjct: 1 MRRTKIVCTVGPASADEATLEQMISSGMNVARLNFSHGDHDSHQQLIERIRAVAK----R 56
Query: 402 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 581
L P +AI D GP+IR G L G V L +G+ + L ++ + G D + VDY
Sbjct: 57 LNQP--VAILQDLCGPKIRLGQLPEQG---VRLHQGDAVSLCSTG---QAGEGD-LPVDY 107
Query: 582 KNITNVVKPGNRIFIDDGLISI 647
++ V+ G+ I + DGL+ +
Sbjct: 108 PSLHEDVQVGDSIMLSDGLMEL 129
>UniRef50_A3I0G9 Cluster: Pyruvate kinase; n=3;
Flexibacteraceae|Rep: Pyruvate kinase - Algoriphagus sp.
PR1
Length = 476
Score = 92.7 bits (220), Expect = 7e-18
Identities = 54/138 (39%), Positives = 76/138 (55%)
Frame = +3
Query: 237 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 416
I+ TIGPAS N + + G NV R+NFSHGSH+ H E I R+ K + LG
Sbjct: 11 ILATIGPASNNYETISSLAAAGANVFRLNFSHGSHDIHQEVIEIIRKINKEQNLNLG--- 67
Query: 417 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 596
I D +GP+IR G +E G VE+K GE K+T ++D G + + Y+N+
Sbjct: 68 ---ILQDLQGPKIRVGEVENNG---VEIKPGE--KITITND-PVVGTSTLVSTVYQNLPQ 118
Query: 597 VVKPGNRIFIDDGLISII 650
V G+RI IDDG + ++
Sbjct: 119 DVVSGDRILIDDGNLEVV 136
>UniRef50_Q0W8N0 Cluster: Pyruvate kinase; n=7; cellular
organisms|Rep: Pyruvate kinase - Uncultured methanogenic
archaeon RC-I
Length = 583
Score = 92.3 bits (219), Expect = 9e-18
Identities = 54/142 (38%), Positives = 77/142 (54%)
Frame = +3
Query: 222 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 401
+R + I+CTIGPA + +LEK+ GMNVAR+N SH HE+ +TI N R S
Sbjct: 1 MRKTKIVCTIGPACDSQDMLEKLAVAGMNVARLNMSHADHEHTVQTINNIR----MVSEA 56
Query: 402 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 581
+G P + I +D +GP+IR G L+ LK G T LTT G++ + V +
Sbjct: 57 IGKP--IGILMDLQGPKIRVGTLQ----QPANLKPGGTFTLTTR---DVPGDSQEVNVPF 107
Query: 582 KNITNVVKPGNRIFIDDGLISI 647
K + V G + +DDGLI +
Sbjct: 108 KELPQSVSTGQTLLLDDGLIEL 129
>UniRef50_Q1AXJ8 Cluster: Pyruvate kinase; n=1; Rubrobacter
xylanophilus DSM 9941|Rep: Pyruvate kinase - Rubrobacter
xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 477
Score = 91.9 bits (218), Expect = 1e-17
Identities = 52/142 (36%), Positives = 84/142 (59%)
Frame = +3
Query: 222 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 401
+R + I+ T+GPA+ + + ++ G++V R+NFSHG+H+ H + R REA +A+
Sbjct: 3 VRRTKIVATLGPATSSEESIGALVRAGVDVMRLNFSHGTHDMHLDNARTVREA----AAE 58
Query: 402 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 581
G ++AI D +GP+IRTG +EGG EL +G + + D+ G+A + Y
Sbjct: 59 AGR--NVAIMQDLQGPKIRTGEVEGG----TELVEGSRV-VIAPGDF--VGDASRLSTSY 109
Query: 582 KNITNVVKPGNRIFIDDGLISI 647
+ VKPG+R+ IDDGLI +
Sbjct: 110 DRLAQDVKPGHRLLIDDGLIGL 131
>UniRef50_P94685 Cluster: Pyruvate kinase; n=8; Chlamydiaceae|Rep:
Pyruvate kinase - Chlamydia trachomatis
Length = 485
Score = 91.9 bits (218), Expect = 1e-17
Identities = 53/138 (38%), Positives = 77/138 (55%)
Frame = +3
Query: 237 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 416
IICTIGPA+ +LEK+++ GMNVAR+NFSHG+HE H TI +E +
Sbjct: 7 IICTIGPATNTPEMLEKLLDAGMNVARLNFSHGTHESHGRTIAILKELREKRQV------ 60
Query: 417 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 596
LAI LDTKGPEIR G +E + ++++ G+ + L + K + T+Y +
Sbjct: 61 PLAIMLDTKGPEIRLGQVE----SPIKVQPGDRLTLVSKEILGSKESGVTLYPSC--VFP 114
Query: 597 VVKPGNRIFIDDGLISII 650
V+ + IDDG I +
Sbjct: 115 YVRERAPVLIDDGYIQAV 132
>UniRef50_UPI00015BD1E0 Cluster: UPI00015BD1E0 related cluster; n=1;
unknown|Rep: UPI00015BD1E0 UniRef100 entry - unknown
Length = 477
Score = 91.1 bits (216), Expect = 2e-17
Identities = 51/140 (36%), Positives = 81/140 (57%)
Frame = +3
Query: 237 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 416
I+CTIGPAS+ V L KM+E GMN+AR+NF+HGS E H + N R+A K
Sbjct: 11 IVCTIGPASQEVETLTKMIENGMNIARINFAHGSFEEHETVVENIRKASKIVGK------ 64
Query: 417 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 596
+ I D GP+IR G ++ +E+KKG+ + L+ EK I +++K+ +
Sbjct: 65 DVTIMGDLPGPKIRIGDIK-----PMEIKKGDILILS------EKPQEGVIPINFKDFSK 113
Query: 597 VVKPGNRIFIDDGLISIICQ 656
VK G+ I+++DG + ++ +
Sbjct: 114 YVKVGDSIYMNDGFVELMVE 133
>UniRef50_Q08SK3 Cluster: Pyruvate kinase; n=2;
Cystobacterineae|Rep: Pyruvate kinase - Stigmatella
aurantiaca DW4/3-1
Length = 481
Score = 91.1 bits (216), Expect = 2e-17
Identities = 54/142 (38%), Positives = 82/142 (57%)
Frame = +3
Query: 222 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 401
+R + IICT+GPAS V+E ++ GMNVAR+NFSHG +E H + R+ S K
Sbjct: 16 MRKAKIICTLGPASDTPEVIEGLVRAGMNVARINFSHGVYEDHRRRVNTLRKV----SRK 71
Query: 402 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 581
LG P +AI D +GP+IR G EGG ++ ++ G+T+ +TT + G I
Sbjct: 72 LGIP--VAILQDIQGPKIRLGRFEGG---QLLVQAGQTVTVTTRA---VLGQGTLIPTPV 123
Query: 582 KNITNVVKPGNRIFIDDGLISI 647
+++T V G+ I +DDG + +
Sbjct: 124 RSLTRDVTRGDMILLDDGRVRL 145
>UniRef50_A7CUA8 Cluster: Pyruvate kinase; n=1; Opitutaceae
bacterium TAV2|Rep: Pyruvate kinase - Opitutaceae
bacterium TAV2
Length = 480
Score = 91.1 bits (216), Expect = 2e-17
Identities = 51/144 (35%), Positives = 86/144 (59%), Gaps = 2/144 (1%)
Frame = +3
Query: 222 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 401
IR + I+ T+GPA+ + +LEK++ G +VAR+N +H +HE+ IR RE K +
Sbjct: 10 IRRTKIVFTLGPATESEEMLEKLIRAGADVARLNMAHANHEWTRMIIRRIREVSK----R 65
Query: 402 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNAD--TIYV 575
+G +AI +D KGPEIRTG + S+ +ELK GE T + + + ++ V
Sbjct: 66 VGR--EIAIMMDIKGPEIRTGDV----SSPIELKAGEIFDFTIRPGAAQDSSEEVRSVDV 119
Query: 576 DYKNITNVVKPGNRIFIDDGLISI 647
+YK++ N ++ G+ + +D+GLI +
Sbjct: 120 NYKDLVNDIRVGDTVLVDNGLIRL 143
>UniRef50_A5C814 Cluster: Pyruvate kinase; n=1; Vitis vinifera|Rep:
Pyruvate kinase - Vitis vinifera (Grape)
Length = 621
Score = 91.1 bits (216), Expect = 2e-17
Identities = 50/141 (35%), Positives = 82/141 (58%)
Frame = +3
Query: 225 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 404
R + I+CTIGP++ + ++ K+ ETGMNVAR+N SHG H H +TI +E + K+
Sbjct: 166 RKTKIVCTIGPSTSSREMIWKLAETGMNVARLNMSHGDHASHKKTIDLVKEYNAQFEDKV 225
Query: 405 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 584
+AI LDTKGPE+R+G + + LK+G+ T + +T+ V+Y
Sbjct: 226 -----IAIMLDTKGPEVRSGDV----PKPIMLKEGQEFNFTIKRGVSSE---NTVSVNYD 273
Query: 585 NITNVVKPGNRIFIDDGLISI 647
+ N V+ G+ + +D G++S+
Sbjct: 274 DFVNDVEVGDILLVDGGMMSL 294
>UniRef50_Q747D6 Cluster: Pyruvate kinase; n=6;
Desulfuromonadales|Rep: Pyruvate kinase - Geobacter
sulfurreducens
Length = 480
Score = 90.6 bits (215), Expect = 3e-17
Identities = 53/144 (36%), Positives = 85/144 (59%)
Frame = +3
Query: 225 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 404
R + II T+GP S + ++ ++M+ G++V R+NFSHGS++ E I A + SA+
Sbjct: 6 RKTKIIATLGPVSSSPDMIRQLMDAGVDVFRLNFSHGSNDQRREVI----AAIRRLSAER 61
Query: 405 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 584
G + I D +GP+IRTG +E G + L +G+++ +TT G TI Y+
Sbjct: 62 GK--EIGILADLQGPKIRTGRMENGA---IPLVRGDSLDITTDEVLGRPGLISTI---YQ 113
Query: 585 NITNVVKPGNRIFIDDGLISIICQ 656
++ + VKPG+RI +DDGLI + Q
Sbjct: 114 SLPHDVKPGSRILLDDGLIELRVQ 137
>UniRef50_Q1Q4I4 Cluster: Strongly similar to pyruvate kinase; n=1;
Candidatus Kuenenia stuttgartiensis|Rep: Strongly
similar to pyruvate kinase - Candidatus Kuenenia
stuttgartiensis
Length = 472
Score = 90.2 bits (214), Expect = 4e-17
Identities = 55/141 (39%), Positives = 80/141 (56%)
Frame = +3
Query: 225 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 404
R + I+CTIGPAS + A++E+++ GMNVAR+NFSHG H E I + R + S KL
Sbjct: 5 RKTKIVCTIGPASNSPAMIEQLICAGMNVARLNFSHGELSQHKECISHIR----AISEKL 60
Query: 405 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 584
P +A+ D GP+IR G+L G V LK +T LTT + GN I ++Y
Sbjct: 61 MQP--VAVLQDLSGPKIRIGMLSGDA---VTLKTNDTFTLTTRNIV---GNERVISINYS 112
Query: 585 NITNVVKPGNRIFIDDGLISI 647
++ V G+ + + DG I +
Sbjct: 113 DLPMNVSIGDTLLLSDGEIEV 133
>UniRef50_Q1NTW3 Cluster: Pyruvate kinase; n=1; delta
proteobacterium MLMS-1|Rep: Pyruvate kinase - delta
proteobacterium MLMS-1
Length = 493
Score = 90.2 bits (214), Expect = 4e-17
Identities = 52/141 (36%), Positives = 80/141 (56%)
Frame = +3
Query: 225 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 404
R + I+CTIGPA+ + + ++ E GMNVAR+N SHGS E+H I N + K Y+
Sbjct: 16 RRTKIVCTIGPATASFEAICRLAEQGMNVARLNMSHGSREWHRGVIGNIKRYNKKYAG-- 73
Query: 405 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 584
SLA+ LDT+G EIR+G L+ ++EL+ G+ + LTT Q + + V +
Sbjct: 74 ----SLAVLLDTRGAEIRSGDLK----QDLELRVGDGLTLTTRR--QAELEPGCVEVSHD 123
Query: 585 NITNVVKPGNRIFIDDGLISI 647
V PG+ I +D G++ +
Sbjct: 124 GFVAEVTPGDIILVDGGMLRL 144
>UniRef50_Q1IHI1 Cluster: Pyruvate kinase; n=2; Bacteria|Rep:
Pyruvate kinase - Acidobacteria bacterium (strain
Ellin345)
Length = 509
Score = 89.0 bits (211), Expect = 9e-17
Identities = 50/141 (35%), Positives = 78/141 (55%)
Frame = +3
Query: 225 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 404
R + I+CTIGPA A ++++M GM+VAR+NFSHG+H+ H I+ R+
Sbjct: 20 RRAKIVCTIGPACNTEAAMQELMRAGMDVARLNFSHGTHDEHLVVIQRLRKVAAEEQR-- 77
Query: 405 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 584
S+ I D +GP+IRTGLL+ V L+ G T+ +T G+A + ++
Sbjct: 78 ----SICILQDLQGPKIRTGLLK--DHKPVMLETGNTVTITPRDIV---GDASLLATTFQ 128
Query: 585 NITNVVKPGNRIFIDDGLISI 647
+ V+PG+RI + DG I +
Sbjct: 129 TLALDVQPGSRILLSDGKIEL 149
>UniRef50_Q5C2V0 Cluster: Pyruvate kinase; n=1; Schistosoma
japonicum|Rep: Pyruvate kinase - Schistosoma japonicum
(Blood fluke)
Length = 168
Score = 89.0 bits (211), Expect = 9e-17
Identities = 44/136 (32%), Positives = 80/136 (58%)
Frame = +3
Query: 171 SQLQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYH 350
S +QH+ ID ++R + ++CT+G + +++M+++GMN+ R+N S G+ E +
Sbjct: 25 SLMQHISNQSIDHAPFFVRHTNLVCTLGDHWDSDEKIDQMIKSGMNILRLNLSMGTKEKY 84
Query: 351 AETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTT 530
AE IR R E+SY +P S+ IALD P +RTGL+ A V ++ G+ + LT
Sbjct: 85 AEVIRRVRRLEESYDY---NP-SVGIALDLSAPPVRTGLINESVDAVVVIQTGQMVTLTI 140
Query: 531 SSDYQEKGNADTIYVD 578
+ +Y++ + I+++
Sbjct: 141 NDEYEKNTTSSIIWIN 156
>UniRef50_UPI0000DA20CA Cluster: PREDICTED: similar to Pyruvate
kinase isozyme M2; n=4; Rattus norvegicus|Rep:
PREDICTED: similar to Pyruvate kinase isozyme M2 -
Rattus norvegicus
Length = 123
Score = 88.6 bits (210), Expect = 1e-16
Identities = 44/89 (49%), Positives = 62/89 (69%)
Frame = +3
Query: 177 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 356
L+HMC L+IDS +GIICTIG ++V +L+ M+ +GMNVA +NFSHG+HEYHAE
Sbjct: 27 LEHMCCLEIDSAPIMAHNTGIICTIG---QSVEMLKGMIMSGMNVAHLNFSHGTHEYHAE 83
Query: 357 TIRNCREAEKSYSAKLGSPFSLAIALDTK 443
TI+N +S+++ S+ +ALDTK
Sbjct: 84 TIKNVCATTESFASDPILYLSIVVALDTK 112
>UniRef50_Q9RR62 Cluster: Pyruvate kinase; n=5; Bacteria|Rep:
Pyruvate kinase - Deinococcus radiodurans
Length = 482
Score = 88.2 bits (209), Expect = 2e-16
Identities = 50/141 (35%), Positives = 77/141 (54%)
Frame = +3
Query: 225 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 404
R + I+ T+GPASR+ VL +M++ G+NV R+NFSHG E H +T++ R+ S +
Sbjct: 6 RATKIVATVGPASRSTEVLGRMIDVGLNVVRLNFSHGDLEDHRQTVQMVRDLAVSKGVTI 65
Query: 405 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 584
G I D +GP+IR G G V L G+ +T + +GNA+ + YK
Sbjct: 66 G------ILQDLQGPKIRVGRFAEG---SVTLNPGQKFVITMD---EVEGNAERVGSTYK 113
Query: 585 NITNVVKPGNRIFIDDGLISI 647
+ V PG + +DDG +S+
Sbjct: 114 GLAGDVTPGMTLLLDDGNMSL 134
>UniRef50_Q56301 Cluster: Pyruvate kinase; n=5; Thermococcaceae|Rep:
Pyruvate kinase - Thermococcus litoralis
Length = 220
Score = 88.2 bits (209), Expect = 2e-16
Identities = 51/137 (37%), Positives = 82/137 (59%)
Frame = +3
Query: 237 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 416
II TIGPAS+ ++KM++ GM+VAR+NFSHG+ E HA+TI R+ + +
Sbjct: 14 IIATIGPASKQKESIKKMIKAGMSVARINFSHGTLEEHAKTIETVRDVAEKLERR----- 68
Query: 417 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 596
+AI D G ++R G ++G V L+KG+ + LTT +G+ TI V++K++
Sbjct: 69 -VAILGDLPGLKMRVGKIKGD---SVTLRKGDKVVLTTR---DIEGDETTIPVEFKDLPK 121
Query: 597 VVKPGNRIFIDDGLISI 647
+V G+ I++ DG I +
Sbjct: 122 LVSKGDTIYLSDGYIML 138
>UniRef50_Q6A9P1 Cluster: Pyruvate kinase; n=4; Actinomycetales|Rep:
Pyruvate kinase - Propionibacterium acnes
Length = 477
Score = 87.8 bits (208), Expect = 2e-16
Identities = 50/141 (35%), Positives = 81/141 (57%), Gaps = 3/141 (2%)
Frame = +3
Query: 222 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 401
+R + I+ T+GPA + ++++ME GMN+AR+N SHG + H E + + +S S +
Sbjct: 1 MRRAKIVNTLGPAVTSHDAMKELMEAGMNIARLNMSHGDYSEHQERL----DLVRSVSKE 56
Query: 402 LGSPFSLAIALDTKGPEIRTGLL---EGGGSAEVELKKGETIKLTTSSDYQEKGNADTIY 572
LG ++A D +GP+IRTGL EG + +++LK G+ +TT GN + +
Sbjct: 57 LG--LNVAALADLQGPKIRTGLFEKAEGESNGKIDLKIGDKFTITTDDIV---GNQERVS 111
Query: 573 VDYKNITNVVKPGNRIFIDDG 635
+K + KPG+ I IDDG
Sbjct: 112 TTFKGLPQDCKPGDVILIDDG 132
>UniRef50_Q6YQT6 Cluster: Pyruvate kinase; n=6; Candidatus
Phytoplasma|Rep: Pyruvate kinase - Onion yellows
phytoplasma
Length = 446
Score = 87.4 bits (207), Expect = 3e-16
Identities = 52/137 (37%), Positives = 80/137 (58%)
Frame = +3
Query: 237 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 416
IICT+GPAS + +L+ +++TG+NVAR NFSH +E ++ K+ S KL
Sbjct: 6 IICTLGPASYDKNILQALIQTGLNVARFNFSHAQYEQTKLLMKTI----KTISDKLDK-- 59
Query: 417 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 596
+ + LDTKGPEIRT +G V ++K +K++ + + GNA V Y N+ N
Sbjct: 60 NTGLMLDTKGPEIRTHEFDG----VVTIQKDSEVKISMT---EVLGNAKLFSVSYSNLYN 112
Query: 597 VVKPGNRIFIDDGLISI 647
+K G+ + IDDG +S+
Sbjct: 113 ELKVGDMVNIDDGYLSL 129
>UniRef50_Q1IJ65 Cluster: Pyruvate kinase; n=6; Bacteria|Rep:
Pyruvate kinase - Acidobacteria bacterium (strain
Ellin345)
Length = 485
Score = 87.4 bits (207), Expect = 3e-16
Identities = 49/140 (35%), Positives = 83/140 (59%)
Frame = +3
Query: 237 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 416
I+ TIGPAS + +LE+++ TG++VAR+NFSHG H E I N R A S + G
Sbjct: 10 IVGTIGPASESPEMLERLIRTGLDVARLNFSHGDFSGHRERIANLRAA----SDRAGR-- 63
Query: 417 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 596
++A+ D GP++R G ++ + + L+ G+ LTT S G+ + + +
Sbjct: 64 AVAVLADLPGPKMRLGTIQ---NEPIHLRAGDPFTLTTDSIV---GDNRRCSMSFAALPQ 117
Query: 597 VVKPGNRIFIDDGLISIICQ 656
VVKPG+R++++DGL+ ++ +
Sbjct: 118 VVKPGDRLYLNDGLVHLLVE 137
>UniRef50_Q40546 Cluster: Pyruvate kinase isozyme G, chloroplast
precursor; n=58; Viridiplantae|Rep: Pyruvate kinase
isozyme G, chloroplast precursor - Nicotiana tabacum
(Common tobacco)
Length = 562
Score = 87.4 bits (207), Expect = 3e-16
Identities = 51/155 (32%), Positives = 84/155 (54%), Gaps = 3/155 (1%)
Frame = +3
Query: 192 GLDIDSKSSYI---RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETI 362
G + +S Y+ R + I+CTIGP++ + ++ K+ E GMNVAR+N SHG H H TI
Sbjct: 77 GYSLGQESVYLNSPRKTKIVCTIGPSTSSREMIWKLAEAGMNVARLNMSHGDHASHQRTI 136
Query: 363 RNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDY 542
+E + K+ +AI LDTKGPE+ + G + LK+G+ +
Sbjct: 137 DLVKEYNAQFEDKV-----IAIMLDTKGPEV----ISGDVPKPILLKEGQEFNFSIKRGV 187
Query: 543 QEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISI 647
+ DT+ V+Y + N V+ G+ + +D G++S+
Sbjct: 188 STE---DTVSVNYDDFINDVEAGDILLVDGGMMSL 219
>UniRef50_Q81N35 Cluster: Pyruvate kinase; n=11; Bacillus cereus
group|Rep: Pyruvate kinase - Bacillus anthracis
Length = 352
Score = 86.6 bits (205), Expect = 5e-16
Identities = 49/139 (35%), Positives = 77/139 (55%)
Frame = +3
Query: 240 ICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 419
+CTIGPAS N L K++ GM + R+N SHG+HE H + IR + + S
Sbjct: 6 VCTIGPASNNKETLAKLINNGMKIVRLNLSHGTHESHKDIIRLVKSLDD----------S 55
Query: 420 LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNV 599
+ I D +GP+IR G ++G ++ L+ G++ L T G++ VDY+ I N
Sbjct: 56 IKILGDVQGPKIRLGEIKG---EQITLQAGDSFMLRTQ---PVTGSSTEASVDYEGIAND 109
Query: 600 VKPGNRIFIDDGLISIICQ 656
VK G+RI ++DG + +I +
Sbjct: 110 VKVGSRILMNDGEVELIVE 128
>UniRef50_A4MK73 Cluster: Pyruvate kinase; n=1; Petrotoga mobilis
SJ95|Rep: Pyruvate kinase - Petrotoga mobilis SJ95
Length = 478
Score = 85.8 bits (203), Expect = 8e-16
Identities = 49/138 (35%), Positives = 82/138 (59%)
Frame = +3
Query: 237 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 416
I+CTIGPA+++ +++K++ GMNVAR+N SH + H + + ++ K L PF
Sbjct: 12 IVCTIGPATQDETMIKKLINAGMNVARLNTSHDTIADHEKRVNLIKKIRKD----LNIPF 67
Query: 417 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 596
AI LD +GP+IRTG E + +V L++G+ LT + GN + + ++Y+ +
Sbjct: 68 --AILLDLEGPKIRTGKFE---TDQVMLEEGQKFILTIE---EIVGNKERVSINYRELPK 119
Query: 597 VVKPGNRIFIDDGLISII 650
VK G+ I +DDG I ++
Sbjct: 120 EVKKGDFILLDDGKIRLV 137
>UniRef50_Q9VFG4 Cluster: Pyruvate kinase; n=3; Sophophora|Rep:
Pyruvate kinase - Drosophila melanogaster (Fruit fly)
Length = 1010
Score = 85.0 bits (201), Expect = 1e-15
Identities = 42/95 (44%), Positives = 59/95 (62%)
Frame = +3
Query: 171 SQLQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYH 350
SQL + L + + + L+ IICTIGP+S VL ++ GM V R++FS G+H+ H
Sbjct: 165 SQLDYQSRLQFQAPALRLPLTSIICTIGPSSSQPEVLLNLIHAGMKVVRLDFSDGTHDCH 224
Query: 351 AETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEI 455
+ I+ R+A Y+ + G P SLAIALDTKGP I
Sbjct: 225 CQAIQAARKAIAMYAEETGLPRSLAIALDTKGPVI 259
>UniRef50_A1BQT0 Cluster: Pyruvate kinase; n=2; Eukaryota|Rep:
Pyruvate kinase - Monocercomonoides sp. PA203
Length = 516
Score = 85.0 bits (201), Expect = 1e-15
Identities = 48/148 (32%), Positives = 82/148 (55%)
Frame = +3
Query: 213 SSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSY 392
+S+ L+ I+ T+GPA+ + +++ G+NV RMNFSHG+HE+H + + R+ +
Sbjct: 32 ASFTPLTKIVATLGPATSTYETISQVVTAGVNVIRMNFSHGTHEFHEQLYKIVRKVAED- 90
Query: 393 SAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIY 572
LG +AI D +GP++RT GG ++ +K+G+ + + S + + G T +
Sbjct: 91 ---LGK--EVAIIADLQGPKVRTNTFPGG---KITIKRGDKVSIVGSPEPGKPGVITTKF 142
Query: 573 VDYKNITNVVKPGNRIFIDDGLISIICQ 656
NV +P + IDDGLI +I Q
Sbjct: 143 TPMITHCNVGEP---VLIDDGLIRLIVQ 167
>UniRef50_Q82XE9 Cluster: Pyruvate kinase family; n=130;
Proteobacteria|Rep: Pyruvate kinase family -
Nitrosomonas europaea
Length = 496
Score = 84.6 bits (200), Expect = 2e-15
Identities = 48/140 (34%), Positives = 80/140 (57%)
Frame = +3
Query: 222 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 401
+R + I+ T+GPAS N VL +M+E G++V R+NFSHG+ + H ++ E +S +
Sbjct: 2 MRRTKIVATLGPASSNAEVLGRMLEAGVDVIRINFSHGTKDEHIASV----ELVRSLARS 57
Query: 402 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 581
LG ++ + D +GP+IR G E G ++ LK G+ L + GN + + +DY
Sbjct: 58 LGR--TVGVLADLQGPKIRIGKFEQG---KIRLKTGDEFILDAEC---QLGNQERVGLDY 109
Query: 582 KNITNVVKPGNRIFIDDGLI 641
+ + N V+ G + +DDG I
Sbjct: 110 RELPNDVEAGATLLLDDGRI 129
>UniRef50_Q8YTZ8 Cluster: Pyruvate kinase; n=3; Nostocaceae|Rep:
Pyruvate kinase - Anabaena sp. (strain PCC 7120)
Length = 476
Score = 84.2 bits (199), Expect = 2e-15
Identities = 53/144 (36%), Positives = 84/144 (58%), Gaps = 1/144 (0%)
Frame = +3
Query: 222 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 401
+R + IICT+GPA+ LE ++E GMNVAR+NFSHG++++HA+T + R+ SA
Sbjct: 1 MRRTKIICTVGPATSAPERLEALVEAGMNVARLNFSHGAYDFHAQTAQYLRQ----ISAD 56
Query: 402 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNA-DTIYVD 578
P +AI D GP+IR G L G + ++ G+ + QEKG++ D + +
Sbjct: 57 RQKP--VAIMQDLCGPKIRLGTLPPEG---LMVEAGQEVTFV----LQEKGSSLDELPLP 107
Query: 579 YKNITNVVKPGNRIFIDDGLISII 650
+ +V+PG I I+DG + +I
Sbjct: 108 LPTLFAMVRPGEPILINDGRVKLI 131
>UniRef50_Q56XD5 Cluster: Pyruvate kinase; n=14; Magnoliophyta|Rep:
Pyruvate kinase - Arabidopsis thaliana (Mouse-ear cress)
Length = 579
Score = 84.2 bits (199), Expect = 2e-15
Identities = 50/148 (33%), Positives = 80/148 (54%)
Frame = +3
Query: 207 SKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEK 386
SK + R + I+CT+GP++ ++ K+ E GMNVARMN SHG H H + I + K
Sbjct: 104 SKPTVRRKTKIVCTVGPSTNTREMIWKLAEAGMNVARMNMSHGDHASHKKVI----DLVK 159
Query: 387 SYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADT 566
Y+A+ ++AI LDTKGPE+R+G L + L G+ T +
Sbjct: 160 EYNAQT-KDNTIAIMLDTKGPEVRSGDL----PQPIMLDPGQEFTFTIE---RGVSTPSC 211
Query: 567 IYVDYKNITNVVKPGNRIFIDDGLISII 650
+ V+Y + N V+ G+ + +D G++S +
Sbjct: 212 VSVNYDDFVNDVEAGDMLLVDGGMMSFM 239
>UniRef50_Q6MAN9 Cluster: Pyruvate kinase; n=1; Candidatus
Protochlamydia amoebophila UWE25|Rep: Pyruvate kinase -
Protochlamydia amoebophila (strain UWE25)
Length = 598
Score = 83.8 bits (198), Expect = 3e-15
Identities = 52/136 (38%), Positives = 75/136 (55%)
Frame = +3
Query: 237 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 416
I+CTIGPA ++ + +++ GMNVAR+NFSHG+ E H TI +EA +L P
Sbjct: 8 IVCTIGPACNSLEKIIELINVGMNVARLNFSHGTQEEHLRTINLLKEAR----CQLNLP- 62
Query: 417 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 596
LAI LDTKGPEIR G + G ++ L G+ +L + G+ + + NI +
Sbjct: 63 -LAIMLDTKGPEIRLGKIRDG---QIFLTVGQKWRLVKK---EVLGDESQVSIFPLNILD 115
Query: 597 VVKPGNRIFIDDGLIS 644
+ G I DDG I+
Sbjct: 116 QLPVGTTILFDDGYIA 131
>UniRef50_O06134 Cluster: Pyruvate kinase; n=29; Bacteria|Rep:
Pyruvate kinase - Mycobacterium tuberculosis
Length = 472
Score = 83.4 bits (197), Expect = 4e-15
Identities = 44/142 (30%), Positives = 76/142 (53%)
Frame = +3
Query: 225 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 404
R I+CT+GPA++ ++ ++E GM+VARMNFSHG ++ H R A + +
Sbjct: 3 RRGKIVCTLGPATQRDDLVRALVEAGMDVARMNFSHGDYDDHKVAYERVRVASDATGRAV 62
Query: 405 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 584
G + D +GP+IR G G + E GET+++T + +G+ D + YK
Sbjct: 63 G------VLADLQGPKIRLGRFASGATHWAE---GETVRITVGAC---EGSHDRVSTTYK 110
Query: 585 NITNVVKPGNRIFIDDGLISII 650
+ G+R+ +DDG ++++
Sbjct: 111 RLAQDAVAGDRVLVDDGKVALV 132
>UniRef50_Q40545 Cluster: Pyruvate kinase isozyme A, chloroplast
precursor; n=15; Magnoliophyta|Rep: Pyruvate kinase
isozyme A, chloroplast precursor - Nicotiana tabacum
(Common tobacco)
Length = 593
Score = 83.4 bits (197), Expect = 4e-15
Identities = 50/139 (35%), Positives = 72/139 (51%)
Frame = +3
Query: 225 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 404
R + +ICTIGPA+ LE++ E GMNVAR+N HG+ E+H I R +
Sbjct: 114 RRTKLICTIGPATCGFEQLERLAEGGMNVARINMCHGTREWHRMVIERLRRLNEE----- 168
Query: 405 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 584
F++AI +DT+G EI G L G SA+ E GE T S + T+ V+Y
Sbjct: 169 -KGFAVAIMMDTEGSEIHMGDLGGASSAKAE--DGEIWNFTVRS-FDPPLPERTVTVNYD 224
Query: 585 NITNVVKPGNRIFIDDGLI 641
VK G+ + +D G++
Sbjct: 225 GFAEDVKVGDELLVDGGMV 243
>UniRef50_Q8F253 Cluster: Pyruvate kinase; n=4; Leptospira|Rep:
Pyruvate kinase - Leptospira interrogans
Length = 478
Score = 83.0 bits (196), Expect = 6e-15
Identities = 47/133 (35%), Positives = 73/133 (54%)
Frame = +3
Query: 237 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 416
I+CTIGPAS + + +++ GM++ARMNFSHG+H+ H R+ E+ + F
Sbjct: 14 IVCTIGPASSSEETILSILKAGMDIARMNFSHGTHDSHKRVYDTLRKCEQIFG------F 67
Query: 417 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 596
L I D +GP+IRTG L+ + L K + I++ SD G+ I Y N+
Sbjct: 68 PLGIMADLQGPKIRTGKLK---LNSILLHKNQEIEIVPDSDI--LGDEHKIGCTYPNLIR 122
Query: 597 VVKPGNRIFIDDG 635
++ ++I IDDG
Sbjct: 123 DIQEEDKILIDDG 135
>UniRef50_Q8SQP0 Cluster: Pyruvate kinase; n=1; Encephalitozoon
cuniculi|Rep: Pyruvate kinase - Encephalitozoon cuniculi
Length = 519
Score = 83.0 bits (196), Expect = 6e-15
Identities = 47/140 (33%), Positives = 86/140 (61%)
Frame = +3
Query: 228 LSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLG 407
L+ I+CTIGP + + ++++++ GM++AR+NFSHGS E H E IRN R+ ++ G
Sbjct: 96 LTKIVCTIGPRTSSREKIKELIDAGMSIARLNFSHGSREAHLEVIRNIRD------SRSG 149
Query: 408 SPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKN 587
+ ++IALDT+GPE+R L +++++ GE ++ + S ++ I++ +
Sbjct: 150 AGRHVSIALDTRGPEVR---LRTPEMKDIKVEGGEVLRFSLLSSEKD------IWIPGVD 200
Query: 588 ITNVVKPGNRIFIDDGLISI 647
+ + + NR+FIDDG I +
Sbjct: 201 LKS-LGVDNRVFIDDGAIEL 219
>UniRef50_Q4YDL9 Cluster: Putative uncharacterized protein; n=1;
Plasmodium berghei|Rep: Putative uncharacterized protein
- Plasmodium berghei
Length = 158
Score = 81.8 bits (193), Expect = 1e-14
Identities = 47/123 (38%), Positives = 69/123 (56%)
Frame = +3
Query: 237 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 416
I+CT+GPA ++V L ++++ GM++ R NFSHG+H+ H + N +A+
Sbjct: 41 IVCTLGPACKSVETLVQLIDAGMDICRFNFSHGTHDDH-KMFENVLKAQAQ-----RPNC 94
Query: 417 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 596
+L + LD KGPEIRTGLL G+ E LK+G +KL +DY G+ I Y T
Sbjct: 95 TLGMLLDNKGPEIRTGLL---GNKEAHLKEGSKLKLV--ADYSYLGDETCIACSYTKCTT 149
Query: 597 VVK 605
K
Sbjct: 150 KCK 152
>UniRef50_Q5IX04 Cluster: Pyruvate kinase; n=1; Prototheca
wickerhamii|Rep: Pyruvate kinase - Prototheca
wickerhamii
Length = 259
Score = 81.0 bits (191), Expect = 2e-14
Identities = 51/142 (35%), Positives = 81/142 (57%)
Frame = +3
Query: 225 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 404
R + +CTIGP S + ++ + GMNV R+N SHG H H + I RE Y+A L
Sbjct: 100 RKTKTVCTIGPTSCDREAFFRLADAGMNVVRLNMSHGDHASHQQVIDLVRE----YNA-L 154
Query: 405 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 584
G +LAI LDTKGPE+R+G L + ++L+KG+ I T + G + I V+Y
Sbjct: 155 GRR-NLAIMLDTKGPEVRSGDL----TQPLDLEKGDLITFTIVAG--ADGTNNRIGVNYD 207
Query: 585 NITNVVKPGNRIFIDDGLISII 650
+ V+ G+ + +D G+++++
Sbjct: 208 GFIDDVEVGDMLLVDGGIMTML 229
>UniRef50_Q44473 Cluster: Pyruvate kinase; n=4; Proteobacteria|Rep:
Pyruvate kinase - Agrobacterium vitis (Rhizobium vitis)
Length = 482
Score = 80.2 bits (189), Expect = 4e-14
Identities = 49/141 (34%), Positives = 75/141 (53%)
Frame = +3
Query: 225 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 404
R S I+ T+GPAS + +L + G++ R+NFSHG+ HAE RN R E+ + A
Sbjct: 7 RRSKIVATVGPASSSPDMLRSLFLAGVDTFRLNFSHGARADHAEVYRNIRALEQEHDA-- 64
Query: 405 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 584
++A+ D +GP+IR G+L G ++L +G TI + E N I + ++
Sbjct: 65 ----AIAVLQDLQGPKIRIGVLAHG---RLDLARGSTIGFILGREGGEGMN--DIPLPHR 115
Query: 585 NITNVVKPGNRIFIDDGLISI 647
I V PG + IDDG I +
Sbjct: 116 EIFEVAVPGMDLLIDDGRIKV 136
>UniRef50_UPI0000D56D72 Cluster: PREDICTED: similar to CG7070-PB,
isoform B; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG7070-PB, isoform B - Tribolium castaneum
Length = 535
Score = 79.8 bits (188), Expect = 5e-14
Identities = 46/152 (30%), Positives = 80/152 (52%)
Frame = +3
Query: 177 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 356
L+H+ L S+ RL+ I P ++ +E+ ++ GM VA + + + + E
Sbjct: 44 LEHLARLQEKSRVRRKRLTQFSVIIPPRI-SIEHIEEFLKAGMTVALIRMDYFTVDEIEE 102
Query: 357 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS 536
+ R + K+G + +AI LD EI+TG L E+EL+KG+T K+
Sbjct: 103 MVAMIRNVVDDFGKKIGRVYPIAIGLDVSEQEIKTGKLLKP-LKEIELEKGQTTKIVAKP 161
Query: 537 DYQEKGNADTIYVDYKNITNVVKPGNRIFIDD 632
++ + + + IYV+Y+NI +VVKPG+ + I D
Sbjct: 162 EFANRVSKEFIYVNYENIADVVKPGDSLIIGD 193
>UniRef50_Q6KHW9 Cluster: Pyruvate kinase; n=3; Mycoplasma|Rep:
Pyruvate kinase - Mycoplasma mobile
Length = 483
Score = 79.8 bits (188), Expect = 5e-14
Identities = 55/140 (39%), Positives = 76/140 (54%)
Frame = +3
Query: 231 SGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGS 410
S +I TIGP+S+N +L++MM GM R NFSHG HAE + N K + +L
Sbjct: 17 SKMIATIGPSSQNKEILKQMMLKGMTTVRANFSHGD---HAEQL-NKFVLAKEVAKELNL 72
Query: 411 PFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNI 590
P SL LDTKGPEIR G ++ GS ++E+ K T+ LT Y+ T + +
Sbjct: 73 PMSL--MLDTKGPEIRVGKMK-DGSQKIEVGKIITV-LTDEVSYKTFEGIPTKFTVSHRM 128
Query: 591 TNVVKPGNRIFIDDGLISII 650
VK G+ I DDG ++ I
Sbjct: 129 DKDVKVGSYILFDDGKLTTI 148
>UniRef50_Q2JLA2 Cluster: Pyruvate kinase; n=2; Synechococcus|Rep:
Pyruvate kinase - Synechococcus sp. (strain
JA-2-3B'a(2-13)) (Cyanobacteria bacteriumYellowstone
B-Prime)
Length = 619
Score = 79.8 bits (188), Expect = 5e-14
Identities = 51/141 (36%), Positives = 72/141 (51%)
Frame = +3
Query: 225 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 404
R + I+ TIGPAS N A+L +M+ G R+NFSHG HE H +IR R+ + L
Sbjct: 8 RRTKIVATIGPASSNPAILREMILQGATTLRLNFSHGDHELHRRSIRLIRQT----AMDL 63
Query: 405 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 584
G +AI D +GP+IR G G + LK G+ LT+ G+ + +V Y
Sbjct: 64 G--IQVAILQDLQGPKIRLGKFAEG---SITLKAGDPFVLTSK---PVLGSQERSWVTYD 115
Query: 585 NITNVVKPGNRIFIDDGLISI 647
+ V G I IDDG + +
Sbjct: 116 KLAQEVPEGATILIDDGRVEM 136
>UniRef50_Q2I6K6 Cluster: Pyruvate kinase; n=1; uncultured delta
proteobacterium DeepAnt-32C6|Rep: Pyruvate kinase -
uncultured delta proteobacterium DeepAnt-32C6
Length = 466
Score = 79.8 bits (188), Expect = 5e-14
Identities = 50/143 (34%), Positives = 74/143 (51%)
Frame = +3
Query: 222 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 401
+R + I+CTIGPA+ + +++ GM+ AR+NFSHG+ + HA RE + +
Sbjct: 1 MRRAKIVCTIGPATHTREGIRALIDAGMDCARLNFSHGTQQGHARVAALVRE----LATE 56
Query: 402 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 581
G P +A+ D GP+IR G G VEL +G LTT G ++Y
Sbjct: 57 AGRP--IALLADLCGPKIRVGRFPEGA---VELVEGTAFTLTTR---DVAGTDKQASINY 108
Query: 582 KNITNVVKPGNRIFIDDGLISII 650
+ V PG+ I IDDGLI ++
Sbjct: 109 AALPQDVDPGDAIMIDDGLIRLV 131
>UniRef50_A4APL1 Cluster: Pyruvate kinase; n=15; Bacteroidetes|Rep:
Pyruvate kinase - Flavobacteriales bacterium HTCC2170
Length = 480
Score = 79.0 bits (186), Expect = 9e-14
Identities = 43/138 (31%), Positives = 76/138 (55%)
Frame = +3
Query: 222 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 401
I+ + I+ T+GPA+ V+ M++ G++V R+NFSH +E ++ RE + +
Sbjct: 4 IKKTKIVATLGPATSKKEVIIDMIKAGVDVFRINFSHADYEDVTARVKMIREVNEEIDS- 62
Query: 402 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 581
++AI D +GP++R G++ G EV + G+ I T ++ GN++ +Y++Y
Sbjct: 63 -----NIAILGDLQGPKLRVGVMSG----EVVVTPGDEIDFVTGEPFE--GNSERVYMNY 111
Query: 582 KNITNVVKPGNRIFIDDG 635
V PG RI +DDG
Sbjct: 112 AAFPKDVNPGERILLDDG 129
>UniRef50_A1WED1 Cluster: Pyruvate kinase; n=1; Verminephrobacter
eiseniae EF01-2|Rep: Pyruvate kinase - Verminephrobacter
eiseniae (strain EF01-2)
Length = 496
Score = 78.6 bits (185), Expect = 1e-13
Identities = 50/139 (35%), Positives = 73/139 (52%)
Frame = +3
Query: 225 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 404
R + I+ T+GPAS A+LE M+ G+NV R+NFSHG + H + R A +
Sbjct: 23 RATKIVATLGPASSEPALLEAMIRAGVNVVRLNFSHGKAQDHIDRAACVRAAAQR----- 77
Query: 405 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 584
+ +AI D +GP+IR G G V L G L S E G+ D + +DYK
Sbjct: 78 -AGHEVAIMADLQGPKIRVGKFAEG---RVLLAPGAPFVLDASR--TEPGDIDGVGLDYK 131
Query: 585 NITNVVKPGNRIFIDDGLI 641
+ + VK G+ + ++DGLI
Sbjct: 132 ELPHDVKGGDLLLLNDGLI 150
>UniRef50_A0L7K0 Cluster: Pyruvate kinase; n=1; Magnetococcus sp.
MC-1|Rep: Pyruvate kinase - Magnetococcus sp. (strain
MC-1)
Length = 569
Score = 78.2 bits (184), Expect = 2e-13
Identities = 49/140 (35%), Positives = 73/140 (52%), Gaps = 1/140 (0%)
Frame = +3
Query: 225 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 404
R + I+ T+GPA +V + +++E G++VAR+N SHG H+ H E I N REA S AK
Sbjct: 3 RRAKIVATLGPACSSVEQITRLIEAGLDVARLNMSHGDHKAHLELIHNVREA--SRIAKR 60
Query: 405 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIY-VDY 581
+A+ D +GP+IR G L+ + L+KG+ + + K D I Y
Sbjct: 61 ----EVALLCDLQGPKIRVGHLD----EPLRLEKGQQWAIIPEGSHPPKLKCDGIIPCTY 112
Query: 582 KNITNVVKPGNRIFIDDGLI 641
+ PG RI DDG +
Sbjct: 113 AGLAKDAVPGCRILFDDGYL 132
>UniRef50_P73534 Cluster: Pyruvate kinase 2; n=37; Bacteria|Rep:
Pyruvate kinase 2 - Synechocystis sp. (strain PCC 6803)
Length = 591
Score = 78.2 bits (184), Expect = 2e-13
Identities = 50/146 (34%), Positives = 82/146 (56%), Gaps = 2/146 (1%)
Frame = +3
Query: 225 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 404
R + I+ TIGPA+++ VL ++++ G R+NFSHG H YH ++IR R+ + +L
Sbjct: 8 RRTKIVATIGPATQSKEVLRQLIQAGATTFRLNFSHGDHAYHQQSIRLIRQ----IAFEL 63
Query: 405 GSPFSLAIALDTKGPEIRTG-LLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTI-YVD 578
P + I D +GP+IR G L GS V+LK G+ LT+ + +TI +
Sbjct: 64 NQP--VGILQDLQGPKIRVGKFLNDAGS--VQLKNGDPYTLTS----RPVECTETISSIS 115
Query: 579 YKNITNVVKPGNRIFIDDGLISIICQ 656
Y+ + + V G RI +DDG + ++ +
Sbjct: 116 YEYLADEVPSGARILLDDGKLEMLVE 141
>UniRef50_A0QNT2 Cluster: Pyruvate kinase; n=1; Mycobacterium
smegmatis str. MC2 155|Rep: Pyruvate kinase -
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Length = 477
Score = 77.8 bits (183), Expect = 2e-13
Identities = 44/141 (31%), Positives = 73/141 (51%)
Frame = +3
Query: 225 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 404
R + I+CT+GPA+ +VL ++++ GM+VAR+NFSH +H H+ RE +
Sbjct: 4 RRAKIVCTLGPATATSSVLTELVDAGMDVARLNFSHSTHAEHSALYGMVREIAAQRGRVV 63
Query: 405 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 584
G + D +GP+IR G G V GE + +TT G+ D + Y
Sbjct: 64 G------VLADLQGPKIRLGCFADG---PVVWATGEHVTITTEDC---PGDHDRVSTTYA 111
Query: 585 NITNVVKPGNRIFIDDGLISI 647
++ V+ G+R+ +DDG + +
Sbjct: 112 GLSQDVRAGDRLLVDDGRVDL 132
>UniRef50_Q9WY51 Cluster: Pyruvate kinase; n=3; Thermotogaceae|Rep:
Pyruvate kinase - Thermotoga maritima
Length = 466
Score = 77.8 bits (183), Expect = 2e-13
Identities = 49/140 (35%), Positives = 77/140 (55%)
Frame = +3
Query: 222 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 401
+R + I+CT+GP + + ++EKM++ G+NV R+N SHG + I ++ + K
Sbjct: 1 MRSTKIVCTVGPRTDSYEMIEKMIDLGVNVFRINTSHGDWNEQEQKILKIKDLRE----K 56
Query: 402 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 581
P +AI +D GP+IRTG LE VELK+G+ LTT + GN + V+
Sbjct: 57 KKKP--VAILIDLAGPKIRTGYLE---KEFVELKEGQIFTLTTK---EILGNEHIVSVNL 108
Query: 582 KNITNVVKPGNRIFIDDGLI 641
++ VK G+ I + DG I
Sbjct: 109 SSLPKDVKKGDTILLSDGEI 128
>UniRef50_Q6AII5 Cluster: Pyruvate kinase; n=1; Desulfotalea
psychrophila|Rep: Pyruvate kinase - Desulfotalea
psychrophila
Length = 581
Score = 77.4 bits (182), Expect = 3e-13
Identities = 47/137 (34%), Positives = 74/137 (54%)
Frame = +3
Query: 237 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 416
II T+GP S++V + +++ GMNVAR+N SHG E + I N +EA K +
Sbjct: 6 IIATLGPQSQSVEEIYSLIQAGMNVARINLSHGDAESYKHLISNVKEARKL------AEK 59
Query: 417 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 596
AI LD +GPEIR +E ++ L GE + +T + E + I +Y +
Sbjct: 60 DTAILLDNRGPEIRVSEME----EDIHLVDGEELVITNRA---ETVSPSRITTNYPQLAG 112
Query: 597 VVKPGNRIFIDDGLISI 647
V+ G+RI +DDG +++
Sbjct: 113 DVQVGSRILLDDGKLAL 129
>UniRef50_Q8ZNW0 Cluster: Pyruvate kinase II; n=173;
Proteobacteria|Rep: Pyruvate kinase II - Salmonella
typhimurium
Length = 480
Score = 76.6 bits (180), Expect = 5e-13
Identities = 52/145 (35%), Positives = 77/145 (53%)
Frame = +3
Query: 213 SSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSY 392
S +R + I+ T+GPA+ LEK++ G NV RMNFSHGS E H RE
Sbjct: 2 SRRLRRTKIVTTLGPATDRDNNLEKVIAAGANVVRMNFSHGSPEDHKMRADKVRE----I 57
Query: 393 SAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIY 572
+AKLG +AI D +GP+IR + G +V L G+ L + E G+ + +
Sbjct: 58 AAKLGR--HVAILGDLQGPKIRVSTFKEG---KVFLNIGDKFLLDANLGKGE-GDKEKVG 111
Query: 573 VDYKNITNVVKPGNRIFIDDGLISI 647
+DYK + V PG+ + +DDG + +
Sbjct: 112 IDYKGLPADVVPGDILLLDDGRVQL 136
>UniRef50_Q8G5M1 Cluster: Pyruvate kinase; n=23;
Actinobacteridae|Rep: Pyruvate kinase - Bifidobacterium
longum
Length = 509
Score = 76.2 bits (179), Expect = 7e-13
Identities = 45/149 (30%), Positives = 82/149 (55%), Gaps = 2/149 (1%)
Frame = +3
Query: 207 SKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEK 386
++ +++R + I+ TIGP++ + L K++E GM+VAR+N SHG+ E H + N R+A +
Sbjct: 25 NRQAFMRKAKIVDTIGPSTEDYDNLLKLVEAGMDVARLNRSHGTPEDHLKVYNNVRKASE 84
Query: 387 SYSAKLGSPFSLAIALDTKGPEIRTGLLE--GGGSAEVELKKGETIKLTTSSDYQEKGNA 560
+ ++A +D +GP+IR G + G +V+L+ G+ +TT +G+
Sbjct: 85 ATGR------NVAALVDLQGPKIRCGWFKKNADGEDKVQLQLGQEFVITTD---DVEGDE 135
Query: 561 DTIYVDYKNITNVVKPGNRIFIDDGLISI 647
+K + PG+ I IDDG + +
Sbjct: 136 HITSTTFKGLPGDCHPGDPILIDDGKVRL 164
>UniRef50_A6FYT4 Cluster: Pyruvate kinase; n=1; Plesiocystis
pacifica SIR-1|Rep: Pyruvate kinase - Plesiocystis
pacifica SIR-1
Length = 485
Score = 75.8 bits (178), Expect = 9e-13
Identities = 45/138 (32%), Positives = 75/138 (54%)
Frame = +3
Query: 222 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 401
+R + I+ T+GPAS + ++ +M+ G++ R+NFSHGSHE HA+ RE + S +
Sbjct: 6 LRRAKILGTLGPASNSDEMIGALMDAGLDAVRLNFSHGSHEDHAQVYGKVRE-QSSIRRR 64
Query: 402 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 581
+A+ D +GP+IR G + G + L+ GET+ T D + + + +DY
Sbjct: 65 -----PVAVLGDLQGPKIRVGKIPDPG---MTLETGETLVFLT--DPTAEISQGRVTIDY 114
Query: 582 KNITNVVKPGNRIFIDDG 635
+ K G R+ +DDG
Sbjct: 115 PTLDEEAKVGERVLMDDG 132
>UniRef50_A6DH47 Cluster: Pyruvate kinase; n=1; Lentisphaera
araneosa HTCC2155|Rep: Pyruvate kinase - Lentisphaera
araneosa HTCC2155
Length = 485
Score = 75.8 bits (178), Expect = 9e-13
Identities = 47/141 (33%), Positives = 79/141 (56%), Gaps = 1/141 (0%)
Frame = +3
Query: 237 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 416
I+ T+GP ++ L++++E G++V R+NFSHGSHE HAE I+ A +G
Sbjct: 9 IVSTLGPTTKGR--LKELIEEGVDVFRLNFSHGSHEEHAERIQEVISAATELKRTVG--- 63
Query: 417 SLAIALDTKGPEIRTG-LLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNIT 593
I D +GP+IR G ++EGG ++L+ G+ + +TT E T+ ++ +
Sbjct: 64 ---ILGDLQGPKIRCGKIIEGG----IQLEAGQELVITTDEILGEGSRISTV---FQALP 113
Query: 594 NVVKPGNRIFIDDGLISIICQ 656
VK G+ I +DDGL+ + +
Sbjct: 114 REVKVGDPILMDDGLLEAVVE 134
>UniRef50_Q94KE3 Cluster: Pyruvate kinase; n=25; Magnoliophyta|Rep:
Pyruvate kinase - Arabidopsis thaliana (Mouse-ear cress)
Length = 527
Score = 75.8 bits (178), Expect = 9e-13
Identities = 48/147 (32%), Positives = 82/147 (55%), Gaps = 1/147 (0%)
Frame = +3
Query: 207 SKSSYI-RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAE 383
SKSS+ L+ I+ T+GP SR+V L ++ GM+VAR +FS G +YH ET+ N + A
Sbjct: 21 SKSSFFPALTKIVGTLGPKSRSVEALSGCLKAGMSVARFDFSWGDADYHQETLDNLKVAV 80
Query: 384 KSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNAD 563
+S + KL A+ LDT GPE++ + + LK + LT + D ++ +++
Sbjct: 81 RS-TKKL-----CAVMLDTVGPELQ---VINKSEKAITLKADGLVTLTPNQD--QEASSE 129
Query: 564 TIYVDYKNITNVVKPGNRIFIDDGLIS 644
+ +++ + VK G+ IF+ L +
Sbjct: 130 VLPINFNGLAKAVKKGDTIFVGQYLFT 156
>UniRef50_A7D456 Cluster: Pyruvate kinase; n=2;
Halobacteriaceae|Rep: Pyruvate kinase - Halorubrum
lacusprofundi ATCC 49239
Length = 613
Score = 75.4 bits (177), Expect = 1e-12
Identities = 54/166 (32%), Positives = 82/166 (49%), Gaps = 3/166 (1%)
Frame = +3
Query: 153 TVANVGSQLQHMCGLDID-SKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFS 329
TV NV S CG + +KS +R + I+CTIGPAS + + + + GM+V R+N S
Sbjct: 5 TVTNVHSVATQPCGFFLSCAKSGDMRNAKIVCTIGPASDSRDAIRDLADAGMSVVRLNAS 64
Query: 330 HGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKG 509
HG+ + E I R + ++ P LA+ +D KGPE+RT L+
Sbjct: 65 HGTTAHREEVIERARAVDN----EIDDP--LAVMVDLKGPEVRTAELD------------ 106
Query: 510 ETIKLTTSSD--YQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLI 641
E+I L T S+ + E +A V + PG+ + +DDG I
Sbjct: 107 ESISLATGSEVTFVEGDDATPERVGLTHSIAAAGPGDTVLLDDGRI 152
>UniRef50_Q5V4I8 Cluster: Pyruvate kinase; n=4;
Halobacteriaceae|Rep: Pyruvate kinase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 610
Score = 74.9 bits (176), Expect = 2e-12
Identities = 46/140 (32%), Positives = 73/140 (52%)
Frame = +3
Query: 222 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 401
+R + I+CT+GPAS +V + + + GM+VAR+N SHGS E+ E I R+ +++
Sbjct: 15 MRSAKIVCTLGPASDSVDDIASLAKAGMSVARLNASHGSPEHRREMIDRIRQVDEAVEE- 73
Query: 402 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 581
+A LD GPE+RT ++ ++L +G TI+ D A V
Sbjct: 74 -----PVAAMLDMPGPEVRTAEID----EPIQLTEGSTIRYVVGDD------ATPEEVGL 118
Query: 582 KNITNVVKPGNRIFIDDGLI 641
V+PG+R+ +DDG I
Sbjct: 119 SQSITAVEPGDRVLLDDGRI 138
>UniRef50_A0L5K6 Cluster: Pyruvate kinase; n=5; Proteobacteria|Rep:
Pyruvate kinase - Magnetococcus sp. (strain MC-1)
Length = 483
Score = 73.7 bits (173), Expect = 3e-12
Identities = 45/142 (31%), Positives = 79/142 (55%)
Frame = +3
Query: 222 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 401
IR + II T+GP + + ++ + TG++ R+NFSHGSHE H R E+ +
Sbjct: 4 IRRTKIIATLGPNASSRDFIKHLALTGVDTFRLNFSHGSHEDHRRRHGWIRSVEE----E 59
Query: 402 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 581
LG P L I +D +GP++R G E ++EVEL +G+ L + G+ + + + +
Sbjct: 60 LGRP--LGIMMDLQGPKLRIGTFE---NSEVELVRGQKFALYKE---ERTGDINGVTLPH 111
Query: 582 KNITNVVKPGNRIFIDDGLISI 647
+ V++PG + ++DG I++
Sbjct: 112 NELFQVMRPGLELLLNDGRINL 133
>UniRef50_Q7UF82 Cluster: Pyruvate kinase; n=1; Pirellula sp.|Rep:
Pyruvate kinase - Rhodopirellula baltica
Length = 476
Score = 73.3 bits (172), Expect = 5e-12
Identities = 46/143 (32%), Positives = 74/143 (51%), Gaps = 4/143 (2%)
Frame = +3
Query: 225 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 404
R + II TIGPA+ + L ++E G++V R+N +HG+ E+ E + R+ K S
Sbjct: 5 RHTKIIATIGPATESPEKLAALIEAGVDVMRLNMAHGTPEWVGEIVARIRKVSKDISR-- 62
Query: 405 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTS--SDYQ--EKGNADTIY 572
+A+ +D KGPEIRTG +E +ELK G+ + L T +D E +
Sbjct: 63 ----HVAVMMDVKGPEIRTGAVEDA----IELKAGDELVLFTEDCADQSAVESDGTPRVS 114
Query: 573 VDYKNITNVVKPGNRIFIDDGLI 641
V+Y + + + I +D GL+
Sbjct: 115 VNYLGLPGAIDLDSTILVDSGLL 137
>UniRef50_A6Q7D7 Cluster: Pyruvate kinase; n=19; cellular
organisms|Rep: Pyruvate kinase - Sulfurovum sp. (strain
NBC37-1)
Length = 488
Score = 73.3 bits (172), Expect = 5e-12
Identities = 44/140 (31%), Positives = 75/140 (53%), Gaps = 2/140 (1%)
Frame = +3
Query: 237 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 416
II TIGPA+ + ++ +M G+N+ R+NFSHG+HEYH+E + R+A + G
Sbjct: 7 IIATIGPATDSYEKIKALMCAGVNLFRLNFSHGTHEYHSEVLGRIRKAIEETGLITG--- 63
Query: 417 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS--DYQEKGNADTIYVDYKNI 590
I D GP+IR G+LE + LK G+ ++ Y+ K + ++ +I
Sbjct: 64 ---ILQDISGPKIRVGMLE----EDFILKSGDILEFVKEEIVGYKVKEGVYRLCINEPDI 116
Query: 591 TNVVKPGNRIFIDDGLISII 650
+ ++ G I++ DG+I +
Sbjct: 117 LDQLEVGESIYMYDGIIRAV 136
>UniRef50_Q0C0E8 Cluster: Pyruvate kinase; n=1; Hyphomonas neptunium
ATCC 15444|Rep: Pyruvate kinase - Hyphomonas neptunium
(strain ATCC 15444)
Length = 474
Score = 72.9 bits (171), Expect = 6e-12
Identities = 45/133 (33%), Positives = 73/133 (54%)
Frame = +3
Query: 237 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 416
I+ T+GP SR+ + + E G++V R+NFSHG H H E ++ R AE A +G P
Sbjct: 13 IVATLGPGSRSPREVRALAEAGVDVFRLNFSHGEHAAHLEALKAVRAAE----AAVGWP- 67
Query: 417 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 596
LA D +GP++R G + GGS ++ +K I + ++ + +TI V + I
Sbjct: 68 -LATLADLQGPKVRVGKFD-GGSLKLGFRKEYRIIVGETAP-----DPETIPVPHAEIVA 120
Query: 597 VVKPGNRIFIDDG 635
+++ G+ I DDG
Sbjct: 121 ILEEGDTILADDG 133
>UniRef50_A6Q5W9 Cluster: Pyruvate kinase; n=2;
Epsilonproteobacteria|Rep: Pyruvate kinase -
Nitratiruptor sp. (strain SB155-2)
Length = 458
Score = 71.3 bits (167), Expect = 2e-11
Identities = 48/138 (34%), Positives = 76/138 (55%)
Frame = +3
Query: 228 LSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLG 407
++ I+ TIGP+S + ++K++ G+NV R+NFSH H+ H +I+ RE K KLG
Sbjct: 1 MTKIVATIGPSS--IEKIDKLILAGVNVFRLNFSHADHKTHKASIKKIRETAK----KLG 54
Query: 408 SPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKN 587
+ AI D GP+IR G ++G +EL KG+ I+L + K D + + Y
Sbjct: 55 T--KTAILQDISGPKIRIGEVDG----ILELSKGDKIRLVKT---HPKSKYD-LTLSYPQ 104
Query: 588 ITNVVKPGNRIFIDDGLI 641
I + ++ G +F DG I
Sbjct: 105 IIDDLEVGEYVFFADGTI 122
>UniRef50_A7CAK5 Cluster: Pyruvate kinase; n=3; Ralstonia
pickettii|Rep: Pyruvate kinase - Ralstonia pickettii 12D
Length = 507
Score = 70.5 bits (165), Expect = 3e-11
Identities = 44/148 (29%), Positives = 71/148 (47%)
Frame = +3
Query: 204 DSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAE 383
++K R + I+ T+GPAS + + + + G +V R+NFSHGSHE H + R E
Sbjct: 13 NTKMRRFRNTKILATLGPASSDKDTIRALFDAGADVFRLNFSHGSHEDHRKRYDTVRAVE 72
Query: 384 KSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNAD 563
A+ G P + I D +GP++R G G V LK G+ L G+
Sbjct: 73 ----AETGRP--IGILADMQGPKLRIGTFADG---RVVLKNGDRFVLDRD---PTPGDVT 120
Query: 564 TIYVDYKNITNVVKPGNRIFIDDGLISI 647
+++ + + PG + +DDG I +
Sbjct: 121 RVHLPHPELYAATAPGQSLLLDDGKIRL 148
>UniRef50_Q2TSX0 Cluster: Pyruvate kinase; n=2; cellular
organisms|Rep: Pyruvate kinase - Phaeodactylum
tricornutum
Length = 665
Score = 70.5 bits (165), Expect = 3e-11
Identities = 42/137 (30%), Positives = 71/137 (51%)
Frame = +3
Query: 240 ICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 419
+ T+GPAS N ++EK+ G +V R+NFSHGS E E + RE E+ YS +G
Sbjct: 158 VVTLGPASSNKEMIEKLFLAGADVFRLNFSHGSQEQKKELLIMIREVEEKYSHPIG---- 213
Query: 420 LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNV 599
I D +GP++R G +EL G++ +L + KG+ + + + I
Sbjct: 214 --ILGDLQGPKLRVGEFSKPEGEFLEL--GQSFRLDLDN---AKGDNKRVQLPHPEIIKA 266
Query: 600 VKPGNRIFIDDGLISII 650
+ G+ + +DDG + ++
Sbjct: 267 SELGHALLVDDGKVKLV 283
>UniRef50_Q8IJ37 Cluster: Pyruvate kinase; n=7; Plasmodium|Rep:
Pyruvate kinase - Plasmodium falciparum (isolate 3D7)
Length = 745
Score = 70.5 bits (165), Expect = 3e-11
Identities = 47/138 (34%), Positives = 66/138 (47%), Gaps = 6/138 (4%)
Frame = +3
Query: 240 ICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 419
I TIGPAS N LEK+ G++V R+NFSHG I + R EK Y +G
Sbjct: 102 IATIGPASENFEQLEKLYLNGIDVFRLNFSHGLKSIKKYIINSIRILEKKYDTTIG---- 157
Query: 420 LAIALDTKGPEIRTG------LLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 581
I D +GP+IR G + E + VELK+G+ + GN + + ++Y
Sbjct: 158 --ILGDIQGPKIRIGEFEKNQINENDNNTFVELKEGDLFSFDLMNSL---GNQNRVQLNY 212
Query: 582 KNITNVVKPGNRIFIDDG 635
+ K G I +DDG
Sbjct: 213 PELIKNAKAGQIILLDDG 230
>UniRef50_Q7QVW2 Cluster: Pyruvate kinase; n=1; Giardia lamblia ATCC
50803|Rep: Pyruvate kinase - Giardia lamblia ATCC 50803
Length = 553
Score = 70.1 bits (164), Expect = 4e-11
Identities = 41/150 (27%), Positives = 77/150 (51%)
Frame = +3
Query: 201 IDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREA 380
+D + I CT+GP+S NV V+ M+ G ++ R+NFSHG+ + H + ++A
Sbjct: 30 VDKNHPHFNRVKICCTLGPSSFNVEVIAGMIRAGADIIRINFSHGNTDDHTQIFHKVQQA 89
Query: 381 EKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNA 560
+ K ++AI D +GP++R + +ELK+G+ L ++ G+
Sbjct: 90 -MQLTGK-----TVAIMGDIQGPKLRIAGFSNPDNC-IELKEGQEFTLDHNN---VNGDE 139
Query: 561 DTIYVDYKNITNVVKPGNRIFIDDGLISII 650
+Y+ +K V +P + I ++DG I ++
Sbjct: 140 SRVYLPHKEFFAVCEPNDDIILNDGYIRLV 169
>UniRef50_Q63P20 Cluster: Pyruvate kinase; n=74; Proteobacteria|Rep:
Pyruvate kinase - Burkholderia pseudomallei (Pseudomonas
pseudomallei)
Length = 484
Score = 69.7 bits (163), Expect = 6e-11
Identities = 40/137 (29%), Positives = 71/137 (51%)
Frame = +3
Query: 225 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 404
R + I+ T+GP+S +E + G +V R+NFSHG+H HA +R+ A ++ A++
Sbjct: 13 RSTKIVATLGPSSSTETAIEALARAGADVFRLNFSHGTHADHA--LRHA--AVRAIEARI 68
Query: 405 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 584
G P + + LD +GP++R G G ++ KG G+A + + +
Sbjct: 69 GHP--IGVLLDLQGPKLRVGQFASG---RAQIAKGRPFVFDRD---PAPGDARRVSLPHP 120
Query: 585 NITNVVKPGNRIFIDDG 635
I + +PG+ + +DDG
Sbjct: 121 EIFDAARPGHLLLVDDG 137
>UniRef50_A6C474 Cluster: Pyruvate kinase; n=1; Planctomyces maris
DSM 8797|Rep: Pyruvate kinase - Planctomyces maris DSM
8797
Length = 489
Score = 68.5 bits (160), Expect = 1e-10
Identities = 39/137 (28%), Positives = 76/137 (55%)
Frame = +3
Query: 237 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 416
II T+GPAS + +L+K++ G+++ R+NF+HG HE+ +E ++N E SA++ P
Sbjct: 17 IIATVGPASDSREMLQKLIIAGVDLFRLNFAHGKHEWLSEIVKNIHE----ISAEMEKP- 71
Query: 417 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 596
+ I D GP+IR G+L G E+ ++ + D N + Y+++
Sbjct: 72 -IGILGDLSGPKIRLGVLPGD---EITCRQDMRFRFIQGLD---SDNPQELTCTYESLIG 124
Query: 597 VVKPGNRIFIDDGLISI 647
++ G+ + + DG++++
Sbjct: 125 DLRVGDPVLLADGMVAM 141
>UniRef50_Q2FMN4 Cluster: Pyruvate kinase; n=1; Methanospirillum
hungatei JF-1|Rep: Pyruvate kinase - Methanospirillum
hungatei (strain JF-1 / DSM 864)
Length = 500
Score = 68.5 bits (160), Expect = 1e-10
Identities = 43/145 (29%), Positives = 78/145 (53%)
Frame = +3
Query: 213 SSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSY 392
S +R + II TIGPAS N ++ +M+ +GM++AR+N SHGS +H ET++ R
Sbjct: 29 SCTMRRTKIIATIGPASSNPRIIREMILSGMDIARLNLSHGSPPWHEETVQQIRALADEL 88
Query: 393 SAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIY 572
+ ++G I +D GP++R L+ S ++ G+TI + ++ + I+
Sbjct: 89 NREIG------ILVDIPGPKLRV-LIH---SPPRDVVPGDTIHIAAEHEHA----SGAIH 134
Query: 573 VDYKNITNVVKPGNRIFIDDGLISI 647
V + V PG+ + + DG +++
Sbjct: 135 VHPPDCIPKVCPGDVVLVGDGAVTL 159
>UniRef50_O05118 Cluster: Pyruvate kinase; n=44; Proteobacteria|Rep:
Pyruvate kinase - Methylobacterium extorquens
(Protomonas extorquens)
Length = 483
Score = 68.5 bits (160), Expect = 1e-10
Identities = 44/142 (30%), Positives = 73/142 (51%)
Frame = +3
Query: 225 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 404
R + I+ T+GPAS ++EK+ G +V R+N SH + E E I R E+ +
Sbjct: 10 RRTKIVATLGPASDTPEMIEKLFHAGADVFRINMSHLAREKLPERIEVIRTIEREGKRPI 69
Query: 405 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 584
G I +D +GP++R G G + L+ G+T L SD G+ D +++ +
Sbjct: 70 G------ILVDLQGPKLRLGTFVGDAAV---LENGQTFVL--DSD-PTPGDTDRVFLPHP 117
Query: 585 NITNVVKPGNRIFIDDGLISII 650
I + ++P + I IDDG + +I
Sbjct: 118 EILSALEPSHGILIDDGKLRLI 139
>UniRef50_Q6F1U1 Cluster: Pyruvate kinase; n=10; Mollicutes|Rep:
Pyruvate kinase - Mesoplasma florum (Acholeplasma
florum)
Length = 478
Score = 68.1 bits (159), Expect = 2e-10
Identities = 46/142 (32%), Positives = 72/142 (50%)
Frame = +3
Query: 222 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 401
++ + II T GP++ + ++ E GM R+NFSHG +E I ++ + +
Sbjct: 10 VKRTKIITTTGPSTNEPEQIRELFENGMTTIRLNFSHGDYEEQGYRIAGAKKVRE----E 65
Query: 402 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 581
LG P S I LDTKGPEIR G G EV + TI S ++ + + V Y
Sbjct: 66 LGKPVS--ILLDTKGPEIRVGKFV-DGKQEVTANQSITIYTDAESFKNKECLSGEMTVAY 122
Query: 582 KNITNVVKPGNRIFIDDGLISI 647
+++ +K G+ I IDDG + +
Sbjct: 123 -DMSVDLKIGDTILIDDGKLEM 143
>UniRef50_Q9YEU2 Cluster: Pyruvate kinase; n=1; Aeropyrum
pernix|Rep: Pyruvate kinase - Aeropyrum pernix
Length = 458
Score = 67.3 bits (157), Expect = 3e-10
Identities = 41/135 (30%), Positives = 73/135 (54%)
Frame = +3
Query: 237 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 416
I+ T+GP+S + ++L +M+ G++VAR+N SHG E + + R AE++ ++G
Sbjct: 7 IVATVGPSSSSASILAQMLSLGVDVARINASHGGVEQWNSMLESLRRAEEAVGKRVG--- 63
Query: 417 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 596
+A+D +GP +RT G S V+L+KG+ + L + E + VD +
Sbjct: 64 ---VAVDLEGPRVRT-----GNSEPVKLEKGDLVTL----GFME----GDVPVDARQFFE 107
Query: 597 VVKPGNRIFIDDGLI 641
+ G+ + +DDG I
Sbjct: 108 TIDEGDIVLLDDGKI 122
>UniRef50_A1IEN3 Cluster: Pyruvate kinase; n=1; Candidatus
Desulfococcus oleovorans Hxd3|Rep: Pyruvate kinase -
Candidatus Desulfococcus oleovorans Hxd3
Length = 478
Score = 66.9 bits (156), Expect = 4e-10
Identities = 41/134 (30%), Positives = 70/134 (52%)
Frame = +3
Query: 237 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 416
+I TIGP SR+ AV+EK++ G+ + R+NFSH A+ I++ RE E+
Sbjct: 5 LIATIGPRSRDRAVIEKLVAVGVTIFRLNFSHAGPGDFADVIQSVREIEQQTGT------ 58
Query: 417 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 596
L + D GP+IR G + G A + + G+ ++L + G+A + ++ I
Sbjct: 59 ILTLMGDLSGPKIRIGEVAG---APLSVATGQLVRLGPARAKGAFGDALYLPLELAEILE 115
Query: 597 VVKPGNRIFIDDGL 638
+KPG + + DG+
Sbjct: 116 QLKPGAPVILSDGI 129
>UniRef50_P78031 Cluster: Pyruvate kinase; n=6; Mycoplasma|Rep:
Pyruvate kinase - Mycoplasma pneumoniae
Length = 508
Score = 66.9 bits (156), Expect = 4e-10
Identities = 45/127 (35%), Positives = 65/127 (51%), Gaps = 1/127 (0%)
Frame = +3
Query: 273 AVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPE 452
A +E +++ G+ V R+NFSHG+HE A I+ R+ K KL P S I LDT GPE
Sbjct: 42 ANIENIIKNGVTVIRLNFSHGNHEEQAVRIKIVRDVAK----KLNLPVS--IMLDTNGPE 95
Query: 453 IRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVD-YKNITNVVKPGNRIFID 629
IR + E LK E + TT+ + + N+ N VK G +I +D
Sbjct: 96 IR--VFETAPEGLKILKDSEVVINTTTKEVAKNNQFSVSDASGTYNMVNDVKVGQKILVD 153
Query: 630 DGLISII 650
DG +S++
Sbjct: 154 DGKLSLV 160
>UniRef50_A7QH42 Cluster: Chromosome chr3 scaffold_95, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr3 scaffold_95, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 573
Score = 66.5 bits (155), Expect = 5e-10
Identities = 39/141 (27%), Positives = 75/141 (53%)
Frame = +3
Query: 222 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 401
+R + ++CTIGPA + LE + +GMNVAR+N H + E+H + IR + +
Sbjct: 87 MRKTKLVCTIGPACCLLEDLENLASSGMNVARLNMCHNTWEWHRDVIRKIKRLNEE---- 142
Query: 402 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 581
+ +++ +DT+G +I +++ G V+ + E+I L T+ + E T+ +Y
Sbjct: 143 --KGYCVSVMIDTEGGQIH--VVDHGAPFSVK-AENESIWLFTTQKF-EGSRPFTVQANY 196
Query: 582 KNITNVVKPGNRIFIDDGLIS 644
+ + + G+ + ID G+ S
Sbjct: 197 EGFSEGITVGDEVVIDGGMAS 217
>UniRef50_A6LH43 Cluster: Pyruvate kinase; n=2; Parabacteroides|Rep:
Pyruvate kinase - Parabacteroides distasonis (strain
ATCC 8503 / DSM 20701 / NCTC11152)
Length = 485
Score = 66.1 bits (154), Expect = 7e-10
Identities = 46/133 (34%), Positives = 67/133 (50%)
Frame = +3
Query: 237 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 416
I+ T+ +VA +E + + GMNV R+N +H E + N R + S ++G
Sbjct: 7 IVATVSDQRCDVAFVEALYKAGMNVVRLNTAHMMEEGLTRVVNNVR----TVSDRIG--- 59
Query: 417 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 596
I +DTKGPE+RT + K GE +K+ + D QE + D I V YKN N
Sbjct: 60 ---ILMDTKGPEVRTTTTV--NKEPIPFKTGEIVKVIGNPD-QETSH-DCICVSYKNFVN 112
Query: 597 VVKPGNRIFIDDG 635
+ G+ I IDDG
Sbjct: 113 DLAIGSDILIDDG 125
>UniRef50_Q5ZZ75 Cluster: Pyruvate kinase II; n=4; Legionella
pneumophila|Rep: Pyruvate kinase II - Legionella
pneumophila subsp. pneumophila (strain Philadelphia 1
/ATCC 33152 / DSM 7513)
Length = 474
Score = 64.5 bits (150), Expect = 2e-09
Identities = 42/142 (29%), Positives = 73/142 (51%)
Frame = +3
Query: 222 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 401
+R + I+ T+GPAS+ +L M+ G+NV R+NFSH + I R+ + +
Sbjct: 2 LRRTKIVATLGPASKEPEILRSMLAAGVNVVRINFSHADSS-ALQLIALVRK----IADE 56
Query: 402 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 581
L P +A+ D +GP+IR G + + + L G+ L + G+ + + V Y
Sbjct: 57 LNHP--VAVMADLQGPKIRVGRFQ---NKSITLIDGQNFTLDCMAP-DTLGDINGVSVAY 110
Query: 582 KNITNVVKPGNRIFIDDGLISI 647
N+ N + G+ + I+DGLI +
Sbjct: 111 PNLANELSIGDHLLINDGLIEL 132
>UniRef50_Q0AHE3 Cluster: Pyruvate kinase; n=2;
Nitrosomonadaceae|Rep: Pyruvate kinase - Nitrosomonas
eutropha (strain C71)
Length = 483
Score = 64.5 bits (150), Expect = 2e-09
Identities = 44/138 (31%), Positives = 68/138 (49%), Gaps = 1/138 (0%)
Frame = +3
Query: 237 IICTIGPASRNVAVLEKMMETGM-NVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSP 413
IICT+GPA+ VL +++ GM +VAR N SHG H HA I+ R+ A+
Sbjct: 19 IICTLGPATDQPGVLARLIGAGMMDVARFNLSHGDHASHARRIQQVRQL-----AQQAGR 73
Query: 414 FSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNIT 593
F +A+ +D GP+ R G L G EL G + L +D D + V + +
Sbjct: 74 F-IAVLMDLPGPKFRLGELSNGAR---ELHLGADVILALEAD-----PPDGLPVKHPALL 124
Query: 594 NVVKPGNRIFIDDGLISI 647
++ G +++ DG I +
Sbjct: 125 QALRVGESVYLADGAIRL 142
>UniRef50_P19680 Cluster: Pyruvate kinase; n=1; Spiroplasma
citri|Rep: Pyruvate kinase - Spiroplasma citri
Length = 192
Score = 64.1 bits (149), Expect = 3e-09
Identities = 34/73 (46%), Positives = 44/73 (60%)
Frame = +3
Query: 237 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 416
II TIGP++ + +E++ +TGM R+NFSHG H I RE SAK+G P
Sbjct: 15 IITTIGPSTHSPGAIEELFKTGMTTIRLNFSHGDHAEQGARIVWAREV----SAKIGKPI 70
Query: 417 SLAIALDTKGPEI 455
S + LDTKGPEI
Sbjct: 71 S--VLLDTKGPEI 81
>UniRef50_Q8EWX2 Cluster: Pyruvate kinase; n=1; Mycoplasma
penetrans|Rep: Pyruvate kinase - Mycoplasma penetrans
Length = 498
Score = 63.3 bits (147), Expect = 5e-09
Identities = 45/137 (32%), Positives = 68/137 (49%), Gaps = 4/137 (2%)
Frame = +3
Query: 249 IGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAI 428
I A +N+A L + G+NV R NFSHG +E + RE K +++
Sbjct: 36 IETAKKNLAAL---FDAGVNVVRFNFSHGDYEEQTIRLNLVREVAKEKGV------NIST 86
Query: 429 ALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYV----DYKNITN 596
LDTKGPEIR + EVE+K +++ T+ +E G ++ V N+
Sbjct: 87 MLDTKGPEIR---VYKTSEKEVEIKSDSKVRIYTTK--KEIGTSEKFSVLDSTGTYNMAK 141
Query: 597 VVKPGNRIFIDDGLISI 647
V+PGN IF+DDG + +
Sbjct: 142 DVQPGNTIFVDDGKLKL 158
>UniRef50_Q7P1G4 Cluster: Pyruvate kinase; n=4; Bacteria|Rep:
Pyruvate kinase - Chromobacterium violaceum
Length = 468
Score = 63.3 bits (147), Expect = 5e-09
Identities = 36/141 (25%), Positives = 72/141 (51%)
Frame = +3
Query: 222 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 401
+R + I+ T+GP+S + ++ +G+N+ R+N SHGSH+ H + R AEK+
Sbjct: 2 LRNTKILATLGPSSSAPEKILELARSGVNIFRLNMSHGSHDDHRARLAAIRAAEKTLDRP 61
Query: 402 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 581
+G + +D +GP++R G +K G+ + + +GNA+ + +
Sbjct: 62 IG------VLVDLQGPKLRIGKF----PQPTTVKTGDRYEFVLD---ETEGNAERATLPH 108
Query: 582 KNITNVVKPGNRIFIDDGLIS 644
++PG+ I ++DG ++
Sbjct: 109 PEAFEALEPGHLILVNDGKLA 129
>UniRef50_Q9PF54 Cluster: Pyruvate kinase; n=11;
Xanthomonadaceae|Rep: Pyruvate kinase - Xylella
fastidiosa
Length = 501
Score = 62.9 bits (146), Expect = 7e-09
Identities = 43/141 (30%), Positives = 65/141 (46%)
Frame = +3
Query: 225 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 404
R + I+ T+GPA+ VL+ + + G+NV R+NFSHG A R A ++
Sbjct: 19 RRTRILATLGPATDPPGVLDALFKAGVNVVRLNFSHGDASDQARRAAEVRAAAAHVGVEI 78
Query: 405 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 584
G I D GP+IR G G +V L L S+ G+A + V Y
Sbjct: 79 G------ILADLPGPKIRIGRFTEG---KVRLVADARFDLLADSN-APLGDATQVGVSYL 128
Query: 585 NITNVVKPGNRIFIDDGLISI 647
+ V G+ + +DDGL+ +
Sbjct: 129 GLPQDVAAGDVLLLDDGLMQL 149
>UniRef50_A3DMY9 Cluster: Pyruvate kinase; n=1; Staphylothermus
marinus F1|Rep: Pyruvate kinase - Staphylothermus
marinus (strain ATCC 43588 / DSM 3639 / F1)
Length = 469
Score = 62.9 bits (146), Expect = 7e-09
Identities = 42/135 (31%), Positives = 71/135 (52%)
Frame = +3
Query: 237 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 416
II TIGP+S VL ++++ G++ R+NFSHG+ E ++ RE + Y +
Sbjct: 6 IITTIGPSSGKYEVLSRLIQEGVDGFRINFSHGNPHEWDEWVKMVRELAEKYERE----- 60
Query: 417 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 596
++I D GP++R G L E+K +T+KL E+ +TI V + +
Sbjct: 61 -ISIMGDLPGPQVRIGEL-----PVQEIKAKQTVKLVYKDKVDEE---NTIPVPNRKVFE 111
Query: 597 VVKPGNRIFIDDGLI 641
+++ G+ + IDDG I
Sbjct: 112 ILELGDIVLIDDGKI 126
>UniRef50_Q1ZJ78 Cluster: Pyruvate kinase; n=1; Psychromonas sp.
CNPT3|Rep: Pyruvate kinase - Psychromonas sp. CNPT3
Length = 485
Score = 62.1 bits (144), Expect = 1e-08
Identities = 39/137 (28%), Positives = 73/137 (53%)
Frame = +3
Query: 237 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 416
II T+GPAS++ ++ K++ G+N+ R+NFSHGS + H + C + + SA+LG
Sbjct: 6 IIATLGPASQSEDMIRKLILAGVNIVRLNFSHGSAQEHID----CAKLVRRISAELGK-- 59
Query: 417 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 596
+ + +D +GP+IR + + VEL G+ L + G+ + + Y ++
Sbjct: 60 YVGVLVDLQGPKIRIACFK---NDVVELVAGQRFVLDAKL-AEFDGSVSAVGLGYPDLIA 115
Query: 597 VVKPGNRIFIDDGLISI 647
+ + + +DDG I +
Sbjct: 116 DLNIDDVLLLDDGRIHL 132
>UniRef50_Q0PQH4 Cluster: Pyruvate kinase; n=1; Endoriftia
persephone 'Hot96_1+Hot96_2'|Rep: Pyruvate kinase -
Endoriftia persephone 'Hot96_1+Hot96_2'
Length = 246
Score = 61.7 bits (143), Expect = 2e-08
Identities = 37/139 (26%), Positives = 71/139 (51%)
Frame = +3
Query: 225 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 404
R + I+ T+GPA+ + V++K++ G++V R+N SH H+ E R+ ++ ++
Sbjct: 36 RRTKIVATLGPATDDPKVMDKLIHAGVDVVRLNLSHDPHDQQRERAERIRDRSRASGRQV 95
Query: 405 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 584
G + D +GP+IR G + S V L++ L + G+ + + + Y
Sbjct: 96 G------VLCDLQGPKIRIGRFK---SDFVMLEEDGAFILDAECPLTD-GDDERVGLTYP 145
Query: 585 NITNVVKPGNRIFIDDGLI 641
++ N V G+ + +DDG I
Sbjct: 146 DLINDVARGDTLLLDDGAI 164
>UniRef50_A7APT5 Cluster: Pyruvate kinase family protein; n=1;
Babesia bovis|Rep: Pyruvate kinase family protein -
Babesia bovis
Length = 693
Score = 60.5 bits (140), Expect = 3e-08
Identities = 43/161 (26%), Positives = 77/161 (47%), Gaps = 15/161 (9%)
Frame = +3
Query: 210 KSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKS 389
+ ++ L+ + T+GP++ L +ME G ++ R+NFSHG+ + R R+ E
Sbjct: 105 QGQFMTLTKQVSTLGPSTCTADSLRSIMEAGTDIYRLNFSHGTRLFKLRLTRMIRQLELV 164
Query: 390 YSAKLGSPFSL----AIALDTKGPEIRTGL-----------LEGGGSAEVELKKGETIKL 524
S+ GS + I D +GP++R G +E + VELKKG+
Sbjct: 165 RSSGEGSDSFMVSPKGILGDIQGPKLRIGRFMPNVDAVGKGIESSAAEFVELKKGDKFTF 224
Query: 525 TTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISI 647
T + KG+ + ++ +I + GN I +DDG +++
Sbjct: 225 DT---HDVKGSQTRVRFNFPDILRDLNVGNTIAMDDGNLNL 262
>UniRef50_Q1MPC8 Cluster: Pyruvate kinase; n=4;
Desulfovibrionaceae|Rep: Pyruvate kinase - Lawsonia
intracellularis (strain PHE/MN1-00)
Length = 471
Score = 59.3 bits (137), Expect = 8e-08
Identities = 41/137 (29%), Positives = 67/137 (48%), Gaps = 2/137 (1%)
Frame = +3
Query: 237 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 416
II TIGPAS + L ++++ G+++ R+NFSHG E I RE E +
Sbjct: 5 IIATIGPASNSKETLSQLIQAGVSIFRLNFSHGDSSAFIELISTIRELEHIHQ------I 58
Query: 417 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYV--DYKNI 590
+ I D GP+IR G L G + + KG+ + L ++K D Y+ D+K I
Sbjct: 59 PITIMQDLSGPKIRIGALP--GDVALNVSKGDVLCLGP----EDKRTNDYPYIPFDHKAI 112
Query: 591 TNVVKPGNRIFIDDGLI 641
+ + + + + DG +
Sbjct: 113 LSDLVVNDILILADGTL 129
>UniRef50_Q4N603 Cluster: Pyruvate kinase; n=2; Theileria|Rep:
Pyruvate kinase - Theileria parva
Length = 699
Score = 59.3 bits (137), Expect = 8e-08
Identities = 48/159 (30%), Positives = 79/159 (49%), Gaps = 17/159 (10%)
Frame = +3
Query: 222 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSH-EYH--AETIR--NCREAEK 386
+ L+ + T+GPA+ N ++ + + G++V R+NFSH S H ++TIR E K
Sbjct: 116 LTLTKQVATLGPATNNAESIKSLFDAGVDVFRLNFSHDSRLSKHLVSKTIRQLEINEPPK 175
Query: 387 SYSAKLGSPFS-LAIALDTKGPEIR----------TGLLEGGGSAE-VELKKGETIKLTT 530
+Y +I D +GP++R G+L G E VELK G+ L T
Sbjct: 176 NYPFNGDHVVEHKSILGDIQGPKLRIGKFMPNLDVPGVLPGSKGCEFVELKAGD---LFT 232
Query: 531 SSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISI 647
Y G+ + +D+ I +K G++I +DDG +S+
Sbjct: 233 FDAYDVLGSKSRVQLDFPEILKELKVGDKILLDDGNLSM 271
>UniRef50_A3ALA5 Cluster: Pyruvate kinase; n=3; Oryza sativa|Rep:
Pyruvate kinase - Oryza sativa subsp. japonica (Rice)
Length = 548
Score = 58.8 bits (136), Expect = 1e-07
Identities = 36/139 (25%), Positives = 70/139 (50%)
Frame = +3
Query: 222 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 401
+R + ++CT+GPA V L + GM VAR+N HG +H +R R +
Sbjct: 62 LRKTKLVCTVGPAC--VGALPALARGGMGVARVNLCHGGRGWHRAVMREVRRLNEE---- 115
Query: 402 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 581
F +++ +DT+G ++ + + GG+A V+ + G T S ++ + T++V++
Sbjct: 116 --EGFCVSLMVDTEGSQLL--VADHGGAASVKAEDGSEWLFT--SKRTDESHPFTMHVNF 169
Query: 582 KNITNVVKPGNRIFIDDGL 638
+ + G+ + ID G+
Sbjct: 170 DKFSEDILVGDELVIDGGM 188
>UniRef50_Q64MR8 Cluster: Pyruvate kinase; n=6; Bacteroides|Rep:
Pyruvate kinase - Bacteroides fragilis
Length = 485
Score = 58.0 bits (134), Expect = 2e-07
Identities = 40/138 (28%), Positives = 64/138 (46%)
Frame = +3
Query: 222 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 401
++ + I+ +I +V ++++ + GMNV RMN +H S E I N R
Sbjct: 3 LKQTKIVASISDRRCDVDFIKELFDAGMNVVRMNTAHASREGFEALIANVRAVSN----- 57
Query: 402 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 581
+AI +DTKGPE+RT + + + GE +K+ D + + I V Y
Sbjct: 58 -----RIAILMDTKGPEVRT----TANADPILYQIGEKVKIV--GDPDRETTRECIAVSY 106
Query: 582 KNITNVVKPGNRIFIDDG 635
N + + G I IDDG
Sbjct: 107 PNFVHDLNVGGTILIDDG 124
>UniRef50_A2BLH1 Cluster: Pyruvate kinase; n=1; Hyperthermus
butylicus DSM 5456|Rep: Pyruvate kinase - Hyperthermus
butylicus (strain DSM 5456 / JCM 9403)
Length = 466
Score = 58.0 bits (134), Expect = 2e-07
Identities = 41/137 (29%), Positives = 69/137 (50%)
Frame = +3
Query: 237 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 416
II +IGP+S + V+ ++ E G++ R+NF+HG E REAE+ K G P
Sbjct: 8 IIASIGPSSGSPEVILRLAELGVSGFRINFAHGEPSLWREWAEYVREAER----KTGRP- 62
Query: 417 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 596
LA+ D GP IR G ++ ++L G+ + + E G+ I + + +
Sbjct: 63 -LALIGDLVGPSIRLGRVKN----PIKLNAGDRAEFRCVEE-SEGGDTKIIPLPVRRVYE 116
Query: 597 VVKPGNRIFIDDGLISI 647
V+ G+ I +DDG + +
Sbjct: 117 VLDEGDLIVMDDGRVRL 133
>UniRef50_Q07637 Cluster: Pyruvate kinase; n=44;
Streptococcaceae|Rep: Pyruvate kinase - Lactococcus
lactis subsp. lactis (Streptococcus lactis)
Length = 502
Score = 58.0 bits (134), Expect = 2e-07
Identities = 41/131 (31%), Positives = 62/131 (47%), Gaps = 1/131 (0%)
Frame = +3
Query: 258 ASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALD 437
+++N+A L +E G NV R NFSHG H + AE+ K+G LD
Sbjct: 38 SAKNIAAL---IEEGANVFRFNFSHGDHPEQGARMATVHRAEEIAGHKVG------FLLD 88
Query: 438 TKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYV-DYKNITNVVKPGN 614
TKGPE+RT L G A + + G+ ++ T + + V +I + V+ G
Sbjct: 89 TKGPEMRTELFADGADA-ISVVTGDKFRVATKQGLKSTPELIALNVAGGLDIFDDVEIGQ 147
Query: 615 RIFIDDGLISI 647
I IDDG + +
Sbjct: 148 TILIDDGKLGL 158
>UniRef50_O51323 Cluster: Pyruvate kinase; n=5; cellular
organisms|Rep: Pyruvate kinase - Borrelia burgdorferi
(Lyme disease spirochete)
Length = 477
Score = 58.0 bits (134), Expect = 2e-07
Identities = 40/137 (29%), Positives = 67/137 (48%)
Frame = +3
Query: 225 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 404
+L+ I+ TI ++ + + G+NV R+N +H SHE + I N R+
Sbjct: 4 KLTKIVATISDLRCEPEHIKDLHDAGVNVIRLNTAHQSHEDTIKVIDNVRKISN------ 57
Query: 405 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 584
+A+ +DTKGPE+RT +E + +K G+ + ++T S E N T +Y
Sbjct: 58 ----KIALMIDTKGPEVRTANIEN----PIIVKTGDKVIIST-SPINEPNNFQT---NYD 105
Query: 585 NITNVVKPGNRIFIDDG 635
V G+++ IDDG
Sbjct: 106 GFVKEVPQGSKVLIDDG 122
>UniRef50_P32044 Cluster: Pyruvate kinase; n=2; Thermoplasma|Rep:
Pyruvate kinase - Thermoplasma acidophilum
Length = 544
Score = 57.2 bits (132), Expect = 3e-07
Identities = 38/136 (27%), Positives = 71/136 (52%)
Frame = +3
Query: 237 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 416
I+ TIGPAS + ++++M++ G+++ R+N +H + + + +S + +G
Sbjct: 5 IVATIGPASSSPEIMKQMIDNGLSLVRINSAHAD----IKDVSKITQMVRSINRDVG--- 57
Query: 417 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 596
I +D KGPE+RTG GG T+K+++ DY I ++ N+ +
Sbjct: 58 ---IMIDLKGPELRTGEFAGG-----------TLKISSGKDYV---MGKDIVLNNMNVLS 100
Query: 597 VVKPGNRIFIDDGLIS 644
V+ G+RI + DG +S
Sbjct: 101 AVQVGDRILMSDGEVS 116
>UniRef50_Q6L281 Cluster: Pyruvate kinase; n=2;
Thermoplasmatales|Rep: Pyruvate kinase - Picrophilus
torridus
Length = 555
Score = 56.8 bits (131), Expect = 4e-07
Identities = 39/133 (29%), Positives = 68/133 (51%)
Frame = +3
Query: 237 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 416
+I TIGPAS ++ +++KM G++ R+N +H + Y + + + KS +G
Sbjct: 6 LIATIGPASESMEIIKKMANLGLSCIRINTAHIENGYITKVAKMVDDVNKSEGTYIG--- 62
Query: 417 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 596
+ +D KGPE+RTG + GS +++ K I Y + N D I ++Y NI++
Sbjct: 63 ---LMVDLKGPELRTGKFK-DGSFKIDYNKKYKI------SYNKNDNPD-ILINY-NISD 110
Query: 597 VVKPGNRIFIDDG 635
+ I + DG
Sbjct: 111 FIDDKTLIAMSDG 123
>UniRef50_UPI00006CE5D4 Cluster: pyruvate kinase family protein;
n=1; Tetrahymena thermophila SB210|Rep: pyruvate kinase
family protein - Tetrahymena thermophila SB210
Length = 495
Score = 45.2 bits (102), Expect(2) = 1e-06
Identities = 17/37 (45%), Positives = 29/37 (78%)
Frame = +3
Query: 225 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHG 335
R + I+CT+GP S +V ++ K++++GMNVAR+ + HG
Sbjct: 22 RKTKIVCTLGPQSSSVEMICKLLDSGMNVARITYCHG 58
Score = 29.9 bits (64), Expect(2) = 1e-06
Identities = 13/29 (44%), Positives = 21/29 (72%)
Frame = +3
Query: 441 KGPEIRTGLLEGGGSAEVELKKGETIKLT 527
+GP+IRT LL+ +E+KKG+ +K+T
Sbjct: 61 QGPDIRTSLLK--DKKPIEIKKGQKLKIT 87
>UniRef50_A7PC98 Cluster: Chromosome chr2 scaffold_11, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr2 scaffold_11, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 475
Score = 55.2 bits (127), Expect = 1e-06
Identities = 33/108 (30%), Positives = 57/108 (52%)
Frame = +3
Query: 327 SHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKK 506
SHG H H +TI +E + K+ +AI LDTKGPE+R+G + + LK+
Sbjct: 2 SHGDHASHKKTIDLVKEYNAQFEDKV-----IAIMLDTKGPEVRSGDV----PKPIMLKE 52
Query: 507 GETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISII 650
G+ T + +T+ V+Y + N V+ G+ + +D G++S++
Sbjct: 53 GQEFNFTIKRGVSSE---NTVSVNYDDFVNDVEVGDILLVDGGMMSLV 97
>UniRef50_A3ZTM3 Cluster: Pyruvate kinase; n=1; Blastopirellula
marina DSM 3645|Rep: Pyruvate kinase - Blastopirellula
marina DSM 3645
Length = 490
Score = 54.4 bits (125), Expect = 2e-06
Identities = 39/137 (28%), Positives = 68/137 (49%)
Frame = +3
Query: 237 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 416
I+ T+GPA +LE+M+ G++V R+N +HG + H+ RE S +L P
Sbjct: 15 IVATVGPACNTPEMLEQMILAGVDVFRLNLAHGELDEHSRVATTIRE----ISERLKRP- 69
Query: 417 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 596
+A D GP+IR G L VE + I+ +++ E + +Y+ + +
Sbjct: 70 -VATLADLSGPKIRLGTLVQDPIYCVEEQMYRFIRGDVATEPNE------LVSNYEPLID 122
Query: 597 VVKPGNRIFIDDGLISI 647
VK G+ + + DG I++
Sbjct: 123 EVKVGDNVMLADGTITM 139
>UniRef50_A5JEK8 Cluster: Pyruvate kinase; n=1; Nosema bombycis|Rep:
Pyruvate kinase - Nosema bombycis
Length = 441
Score = 54.0 bits (124), Expect = 3e-06
Identities = 38/140 (27%), Positives = 74/140 (52%)
Frame = +3
Query: 228 LSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLG 407
++ II T+ S + L ++ G+++ R+N SHG+ H +I N R+ K ++G
Sbjct: 5 MTKIIVTVSSVSDDEETLTNFLKEGVHIFRINLSHGTSYQHEHSILNIRKCAK----EMG 60
Query: 408 SPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKN 587
I LDT+GPE+R + E +E+ LK+G+ K+T + ++ I++ +
Sbjct: 61 --IVPVICLDTRGPEVRIEIAE---RSEIPLKEGD--KIT----FSNVRTSNKIFLPIPD 109
Query: 588 ITNVVKPGNRIFIDDGLISI 647
T ++I++DD +++I
Sbjct: 110 FTKFPLK-SKIYLDDAMLAI 128
>UniRef50_A7QTW5 Cluster: Chromosome undetermined scaffold_171,
whole genome shotgun sequence; n=1; Vitis vinifera|Rep:
Chromosome undetermined scaffold_171, whole genome
shotgun sequence - Vitis vinifera (Grape)
Length = 622
Score = 50.4 bits (115), Expect = 4e-05
Identities = 40/146 (27%), Positives = 72/146 (49%), Gaps = 7/146 (4%)
Frame = +3
Query: 225 RLSGIICTIGP-ASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 401
R + I+ T+G + N ++ ++++G + R+N +HG+ +E IR R + S
Sbjct: 258 RTAHIMVTVGQEVTENETLITDILKSGATIIRINCAHGNPSIWSEIIRRVRRS----SQM 313
Query: 402 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQE----KGNADTI 569
L P I +D GP++RTG ++ G V L+ G+ + ++ S ++ + D
Sbjct: 314 LEKP--CRILMDLAGPKLRTGNMK-AGPCFVRLRVGDLLIISLDSSIEQDELTQPTVDAY 370
Query: 570 YVDYKN--ITNVVKPGNRIFIDDGLI 641
V + + + VKPG I DDG I
Sbjct: 371 RVTCPSSFLFDSVKPGEPIAFDDGKI 396
>UniRef50_A1RX09 Cluster: Pyruvate kinase; n=1; Thermofilum pendens
Hrk 5|Rep: Pyruvate kinase - Thermofilum pendens (strain
Hrk 5)
Length = 464
Score = 48.0 bits (109), Expect = 2e-04
Identities = 33/136 (24%), Positives = 63/136 (46%)
Frame = +3
Query: 237 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 416
++ T+GP+S + +++M+ G+N R+NFSH + E + R E
Sbjct: 6 LVATLGPSSWSEETMKRMVAEGVNAFRLNFSHVDYARFEELAKQVRRLETPLR------- 58
Query: 417 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 596
L + D +GP IR G A +++ G+ + T SS +EK + V
Sbjct: 59 PLTLIADLQGPVIRLGEF-----APFQVRPGDRVTFTLSSKTEEK---YAVPVPNGVFFE 110
Query: 597 VVKPGNRIFIDDGLIS 644
+V+ G+ + ++ G ++
Sbjct: 111 IVREGDEVLVEGGRLA 126
>UniRef50_Q22CT0 Cluster: Pyruvate kinase, barrel domain containing
protein; n=1; Tetrahymena thermophila SB210|Rep:
Pyruvate kinase, barrel domain containing protein -
Tetrahymena thermophila SB210
Length = 747
Score = 46.4 bits (105), Expect = 6e-04
Identities = 43/142 (30%), Positives = 72/142 (50%), Gaps = 1/142 (0%)
Frame = +3
Query: 225 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREA-EKSYSAK 401
R + I+ TI + L+ M+E G+N +N ++ + + T+R R+A EK + +
Sbjct: 66 RRTKIVGTISSFYSSYENLKSMVEAGLNSFMVNMAYCTPDLLV-TLRKHRDALEKEFDIQ 124
Query: 402 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 581
L P + + KG +R G L E+ L+KG+ ++ + ++ GN+ VD
Sbjct: 125 L--PITCVL----KGTLVRIGTLM---QPEIFLRKGQEYRIVLN--HKVLGNSLYCAVDD 173
Query: 582 KNITNVVKPGNRIFIDDGLISI 647
K I VK GN+I ID G IS+
Sbjct: 174 KEIIRRVKVGNQILIDYGQISM 195
>UniRef50_Q8MR79 Cluster: Pyruvate kinase; n=3; Sophophora|Rep:
Pyruvate kinase - Drosophila melanogaster (Fruit fly)
Length = 659
Score = 46.0 bits (104), Expect = 8e-04
Identities = 33/117 (28%), Positives = 53/117 (45%), Gaps = 4/117 (3%)
Frame = +3
Query: 300 GMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTG----L 467
G+ +N G+ + I REAE S S +LG P + ++ + TG
Sbjct: 175 GVRCFMVNLFEGTQHDNQSLIVKLREAEISVSKELGFPVTSSVMVKISPRHQFTGGFSTQ 234
Query: 468 LEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGL 638
G VEL +G+ + LT Y ++ NAD IYV+ + + V P + I I + +
Sbjct: 235 FRQEGKKCVELVQGQKVILTVDRQYSDRSNADVIYVNARFLIVDVHPLDFILIGEDI 291
>UniRef50_Q2JJ60 Cluster: Pyruvate kinase; n=5; Bacteria|Rep:
Pyruvate kinase - Synechococcus sp. (strain
JA-2-3B'a(2-13)) (Cyanobacteria bacteriumYellowstone
B-Prime)
Length = 476
Score = 45.6 bits (103), Expect = 0.001
Identities = 36/140 (25%), Positives = 65/140 (46%), Gaps = 1/140 (0%)
Frame = +3
Query: 225 RLSGIICTI-GPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 401
R + I+ T+ A+ +L +++E GMNVAR+N +H + + + R+AE +
Sbjct: 118 RRARIMVTLPSEAAEQPELLLQLLERGMNVARINCAHDEPSVWEKMVAHLRQAEAQTQRR 177
Query: 402 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 581
I LD GP+IRTG + + ++ +G+ I LT + +
Sbjct: 178 ------CKILLDLAGPKIRTGPV-AMPPGKTKVYRGDRILLTAKVPEASADISCQVTCSL 230
Query: 582 KNITNVVKPGNRIFIDDGLI 641
+ ++ G ++IDDG I
Sbjct: 231 PEVLAHLQVGATVWIDDGKI 250
>UniRef50_P46614 Cluster: Pyruvate kinase; n=1; Candida
albicans|Rep: Pyruvate kinase - Candida albicans (Yeast)
Length = 92
Score = 45.2 bits (102), Expect = 0.001
Identities = 18/40 (45%), Positives = 27/40 (67%)
Frame = +3
Query: 525 TTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLIS 644
TT Y+ K + + +DYKNIT V+ PG I++DDG++S
Sbjct: 12 TTDDAYKTKCDDKVMIIDYKNITKVIAPGKIIYVDDGVLS 51
>UniRef50_A3PTF7 Cluster: Pyruvate kinase; n=5; Mycobacterium|Rep:
Pyruvate kinase - Mycobacterium sp. (strain JLS)
Length = 615
Score = 44.8 bits (101), Expect = 0.002
Identities = 31/108 (28%), Positives = 53/108 (49%), Gaps = 1/108 (0%)
Frame = +3
Query: 159 ANVGSQLQHMCGLDIDSKSSYIRLSGIICTI-GPASRNVAVLEKMMETGMNVARMNFSHG 335
ANVG +L +D+ + R + I+ T+ A+ + ++ ++ GMNVAR+N +H
Sbjct: 116 ANVGDELLREHAVDLFGPAPAERATRIMVTLPSSAATDPDLVRDLIARGMNVARINCAHD 175
Query: 336 SHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGG 479
E + R A +S K +A+D GP++RTG + G
Sbjct: 176 DAEAWTAMAGHVRRAAESTGRK------CLVAMDLAGPKLRTGPIRPG 217
>UniRef50_A6LTB0 Cluster: Pyruvate kinase; n=1; Clostridium
beijerinckii NCIMB 8052|Rep: Pyruvate kinase -
Clostridium beijerinckii NCIMB 8052
Length = 340
Score = 44.0 bits (99), Expect = 0.003
Identities = 35/124 (28%), Positives = 58/124 (46%), Gaps = 2/124 (1%)
Frame = +3
Query: 237 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 416
II T+GP ++ AVL+ ++E+G+N R NF HGS E E ++ ++ +
Sbjct: 3 IIGTVGPNVKDRAVLKGIIESGVNALRFNFIHGSAEEFLEFLKMAKDIKS---------- 52
Query: 417 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQE--KGNADTIYVDYKNI 590
+ + LD G ++R + G ++ GE I Y E K + + I V NI
Sbjct: 53 DIQVMLDLSGTKVR---VSGKFQYIFKVYNGEVIYFCGEDKYSEVVKNSKNKIKVIPLNI 109
Query: 591 TNVV 602
N +
Sbjct: 110 KNKI 113
>UniRef50_Q7NJ33 Cluster: Pyruvate kinase; n=1; Gloeobacter
violaceus|Rep: Pyruvate kinase - Gloeobacter violaceus
Length = 501
Score = 43.6 bits (98), Expect = 0.004
Identities = 38/146 (26%), Positives = 63/146 (43%), Gaps = 4/146 (2%)
Frame = +3
Query: 225 RLSGIICTI-GPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 401
R + I+ T+ A + +L ++ GMN AR+N H S + N R AE+
Sbjct: 142 RATRIMVTLPSEAEGDYRLLCALIRAGMNCARINCVHDSETVWERMVGNIRRAEREVGR- 200
Query: 402 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADT---IY 572
+ I +D GP++RTG L + + L+KGE + L ++ D+ +
Sbjct: 201 -----ACRILMDLGGPKLRTGPL----AEPLTLRKGEGLVLCRDAEEGRSACEDSPARVV 251
Query: 573 VDYKNITNVVKPGNRIFIDDGLISII 650
I V+ G + DDG I +
Sbjct: 252 CAVSGIYGGVQVGEAVLFDDGKIESV 277
>UniRef50_A4ARB8 Cluster: Pyruvate kinase; n=1; Flavobacteriales
bacterium HTCC2170|Rep: Pyruvate kinase -
Flavobacteriales bacterium HTCC2170
Length = 624
Score = 43.6 bits (98), Expect = 0.004
Identities = 28/86 (32%), Positives = 47/86 (54%), Gaps = 2/86 (2%)
Frame = +3
Query: 225 RLSGIICTI-GPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 401
R + I+ T+ A+ ++ + K++ GMN AR+N +H + E + I N + A K K
Sbjct: 131 RFTRIMVTLPNTAAEDLGFIRKLLANGMNCARINCAHDTPEDWLKMIDNLKIASKRQRKK 190
Query: 402 LGSPFSLAIALDTKGPEIRTG-LLEG 476
IA+D GP++RTG ++EG
Sbjct: 191 ------CKIAMDLSGPKLRTGPMVEG 210
>UniRef50_A6PU80 Cluster: Pyruvate kinase; n=1; Victivallis vadensis
ATCC BAA-548|Rep: Pyruvate kinase - Victivallis vadensis
ATCC BAA-548
Length = 121
Score = 42.7 bits (96), Expect = 0.007
Identities = 39/133 (29%), Positives = 61/133 (45%)
Frame = +3
Query: 222 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 401
++ + I+ TI ++ +L + + GM+V R+N +H + R+
Sbjct: 1 MKYTKIVATINASTCTEELLRGLYKNGMDVVRLNTAHMEIADMDRIVALVRKVSDK---- 56
Query: 402 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 581
LAI +DTKGP IRT L+ A + LK G+ + LT + QEK + V+Y
Sbjct: 57 ------LAIMVDTKGPNIRTCNLD----APLALKIGDKLDLTGETVPQEK----AVQVNY 102
Query: 582 KNITNVVKPGNRI 620
T V G RI
Sbjct: 103 SKFTAEVPVGARI 115
>UniRef50_Q5KVI2 Cluster: Pyruvate kinase; n=2; Geobacillus|Rep:
Pyruvate kinase - Geobacillus kaustophilus
Length = 660
Score = 41.9 bits (94), Expect = 0.013
Identities = 32/113 (28%), Positives = 55/113 (48%), Gaps = 2/113 (1%)
Frame = +3
Query: 174 QLQHMCGLDIDSKSSYIRLSGIICTIGPA-SRNVAVLEKMMETGMNVARMNFSHGSHEYH 350
QL H + S +R + I+ T+ A ++E+++ GM++AR+N ++GS E
Sbjct: 154 QLLHKRAEAVFGSPSSVRPTRIMVTMDEAWVDEPGLIERLLLYGMDIARINCAYGSPETW 213
Query: 351 AETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTG-LLEGGGSAEVELKK 506
+ R+AEK +L I +D GP+IR L G ++ +KK
Sbjct: 214 EALVAIIRQAEKQLEQQLQGR-RCRIYMDLPGPKIRVDRLAVNAGPMKLSVKK 265
>UniRef50_A1U5Q4 Cluster: Pyruvate kinase; n=2; Marinobacter
aquaeolei VT8|Rep: Pyruvate kinase - Marinobacter
aquaeolei (strain ATCC 700491 / DSM 11845 /
VT8)(Marinobacter hydrocarbonoclasticus (strain DSM
11845))
Length = 626
Score = 41.5 bits (93), Expect = 0.017
Identities = 21/74 (28%), Positives = 41/74 (55%)
Frame = +3
Query: 258 ASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALD 437
++++ +++ +++ GMN R+N +H E E I N + A++ + S + +D
Sbjct: 154 SAQDPSIIRDLLKAGMNCMRINCAHDDPETWLEMINNLQTAKEEFGQ------SCQVFMD 207
Query: 438 TKGPEIRTGLLEGG 479
GP+IRTG +E G
Sbjct: 208 LGGPKIRTGEIEPG 221
>UniRef50_Q9PQV7 Cluster: Pyruvate kinase; n=1; Ureaplasma
parvum|Rep: Pyruvate kinase - Ureaplasma parvum
(Ureaplasma urealyticum biotype 1)
Length = 474
Score = 41.1 bits (92), Expect = 0.023
Identities = 35/127 (27%), Positives = 55/127 (43%), Gaps = 3/127 (2%)
Frame = +3
Query: 279 LEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIR 458
++ ++ +G+N+ RMN SHG + H + ++ K + I DTKGPEIR
Sbjct: 41 IKDLILSGVNIFRMNLSHGDQKIHLFRTQLIKKIADELKIK------VEILFDTKGPEIR 94
Query: 459 TGLLEGGGSAEVELKKGETI---KLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFID 629
+ +K E I K + E D N+ + VK +RI ID
Sbjct: 95 VCEMSDNNFI---IKNSEVIIHCKEKVLGSFNEFSVTDA--TGQYNMISDVKINHRILID 149
Query: 630 DGLISII 650
DG + +I
Sbjct: 150 DGKLILI 156
>UniRef50_Q4IUP8 Cluster: Pyruvate kinase; n=1; Azotobacter
vinelandii AvOP|Rep: Pyruvate kinase - Azotobacter
vinelandii AvOP
Length = 165
Score = 40.7 bits (91), Expect = 0.030
Identities = 18/51 (35%), Positives = 29/51 (56%)
Frame = +3
Query: 225 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCRE 377
R + I+ T+G A+ +E +++ G++V R+NFSHG E H RE
Sbjct: 3 RRTKIVATLGSATETPEAIEGLVKAGVDVVRLNFSHGKAEEHQARATLVRE 53
>UniRef50_A4VPY3 Cluster: Pyruvate kinase; n=1; Pseudomonas stutzeri
A1501|Rep: Pyruvate kinase - Pseudomonas stutzeri
(strain A1501)
Length = 625
Score = 39.9 bits (89), Expect = 0.053
Identities = 24/69 (34%), Positives = 39/69 (56%)
Frame = +3
Query: 258 ASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALD 437
A+ N ++E +++ GM+ AR+N +H + I + R AEK+ LG +ALD
Sbjct: 150 AAHNRDLIEALIKEGMDCARINCAHDDPDSWRAMIEHVRAAEKA----LGR--ECKVALD 203
Query: 438 TKGPEIRTG 464
GP++RTG
Sbjct: 204 LAGPKLRTG 212
>UniRef50_Q97ZD7 Cluster: Pyruvate kinase; n=4; Sulfolobaceae|Rep:
Pyruvate kinase - Sulfolobus solfataricus
Length = 452
Score = 39.9 bits (89), Expect = 0.053
Identities = 42/142 (29%), Positives = 70/142 (49%)
Frame = +3
Query: 222 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 401
+R + I+ T+GP+S K + ++V R+NF+HG H R + ++Y
Sbjct: 1 MRKTKIVATLGPSSEEKV---KELAEYVDVFRINFAHGDETSH----RKYFDLIRTY--- 50
Query: 402 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 581
+P S +I +D GP++R G L+ +E+KKG+ I + +K D I VD
Sbjct: 51 --APES-SIIVDLPGPKLRLGELK----EPIEVKKGDKIV------FSQK---DGIPVDD 94
Query: 582 KNITNVVKPGNRIFIDDGLISI 647
+ + VK + I I DG I +
Sbjct: 95 ELFYSAVKENSDILIADGTIRV 116
>UniRef50_UPI00006CB055 Cluster: hypothetical protein TTHERM_00239360;
n=1; Tetrahymena thermophila SB210|Rep: hypothetical
protein TTHERM_00239360 - Tetrahymena thermophila SB210
Length = 1220
Score = 37.1 bits (82), Expect = 0.37
Identities = 19/66 (28%), Positives = 34/66 (51%)
Frame = +3
Query: 387 SYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADT 566
S S + + F+ LDT GP + + ++++K E+IK+ + YQ KGN+
Sbjct: 924 SKSQQNSNQFNQGNQLDTLGPFENNAVQNSLENISLKIEKNESIKIQSKDIYQNKGNSQF 983
Query: 567 IYVDYK 584
+ +D K
Sbjct: 984 LNIDQK 989
>UniRef50_A0NLM6 Cluster: Pyruvate kinase; n=2;
Alphaproteobacteria|Rep: Pyruvate kinase - Stappia
aggregata IAM 12614
Length = 512
Score = 37.1 bits (82), Expect = 0.37
Identities = 34/126 (26%), Positives = 56/126 (44%), Gaps = 1/126 (0%)
Frame = +3
Query: 258 ASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALD 437
A+ + A + ++ GMNVAR+N +H E + + R A A+L + I +D
Sbjct: 165 AADDPAFVRDLVRKGMNVARLNCAHDGPEAWEKMAAHVRTA-----AELEGR-DVRILMD 218
Query: 438 TKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGN-ADTIYVDYKNITNVVKPGN 614
GP+IRT + +L GE +L + A T V + N ++ G+
Sbjct: 219 IAGPKIRTETVVPQKKTP-KLTIGERFRLVVQETPDAHSDIAVTASVSLPQMVNRLREGD 277
Query: 615 RIFIDD 632
R+ DD
Sbjct: 278 RLLYDD 283
>UniRef50_Q9M3B6 Cluster: Pyruvate kinase; n=1; Arabidopsis
thaliana|Rep: Pyruvate kinase - Arabidopsis thaliana
(Mouse-ear cress)
Length = 710
Score = 37.1 bits (82), Expect = 0.37
Identities = 26/86 (30%), Positives = 43/86 (50%), Gaps = 1/86 (1%)
Frame = +3
Query: 225 RLSGIICTIGP-ASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 401
R + I+ TIG A+ + + +++ G +V R+N +HG E I+ R S
Sbjct: 234 RSTHIMVTIGEEATLSETFITDILKAGTSVIRINCAHGDPSIWGEIIKRVRRT----SQM 289
Query: 402 LGSPFSLAIALDTKGPEIRTGLLEGG 479
L P + +D GP++RTG L+ G
Sbjct: 290 LEMP--CRVHMDLAGPKLRTGTLKPG 313
>UniRef50_Q9VVH0 Cluster: CG12229-PA; n=2; Sophophora|Rep:
CG12229-PA - Drosophila melanogaster (Fruit fly)
Length = 571
Score = 35.9 bits (79), Expect = 0.86
Identities = 28/111 (25%), Positives = 50/111 (45%), Gaps = 11/111 (9%)
Frame = +3
Query: 276 VLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKS-----------YSAKLGSPFSL 422
V + + ET + R +G++ +H +T+ N + K+ +SA+ +
Sbjct: 78 VAKLVTETTHDELRRMLENGTYTFHVDTVGNKPDELKAILDTMNIAISAHSAERELRLTT 137
Query: 423 AIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYV 575
+AL+ G R G L + V L +G + LTT Y+ KG + +YV
Sbjct: 138 GLALEINGECCRVGRLRN--NCTVMLARGGVVTLTTDESYRYKGFKEIVYV 186
>UniRef50_A2STG1 Cluster: Putative anti-sigma regulatory factor,
serine/threonine protein kinase; n=1; Methanocorpusculum
labreanum Z|Rep: Putative anti-sigma regulatory factor,
serine/threonine protein kinase - Methanocorpusculum
labreanum (strain ATCC 43576 / DSM 4855 / Z)
Length = 777
Score = 35.1 bits (77), Expect = 1.5
Identities = 17/48 (35%), Positives = 25/48 (52%)
Frame = +3
Query: 192 GLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHG 335
G ID K +YI+ SG+IC G A + V +KM G + ++ G
Sbjct: 349 GTGIDVKGTYIQNSGMICGTGMAGDGICVAKKMTVYGGKIEATGYTTG 396
>UniRef50_Q4CYW8 Cluster: Putative uncharacterized protein; n=3;
Trypanosoma|Rep: Putative uncharacterized protein -
Trypanosoma cruzi
Length = 435
Score = 34.7 bits (76), Expect = 2.0
Identities = 36/144 (25%), Positives = 60/144 (41%), Gaps = 7/144 (4%)
Frame = +3
Query: 225 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREA--EKSYSA 398
R+SG++ T+ P + A+ E + +A + +H E HA+ C A E+ S+
Sbjct: 30 RVSGLLFTVNPRQESKALRELQLYLHPLIADLEEAHKRVEEHADARGRCDNATTEEQSSS 89
Query: 399 KLGSPFSLAIALDTK---GPEIRTGLLEGGGSAEVELKK--GETIKLTTSSDYQEKGNAD 563
K+ + IA T E+ + GG E+++ + K S D EK + D
Sbjct: 90 KMSTDAGGKIAPSTSSLLAAELAEYITTRGGQRRHEMRRIPMKEEKSDVSDDEDEKKSTD 149
Query: 564 TIYVDYKNITNVVKPGNRIFIDDG 635
+ N +N NR D G
Sbjct: 150 NNNNNNNNNSNNNILRNRSSDDGG 173
>UniRef50_Q9V2V8 Cluster: Pyruvate kinase; n=1; Thermoproteus
tenax|Rep: Pyruvate kinase - Thermoproteus tenax
Length = 446
Score = 34.7 bits (76), Expect = 2.0
Identities = 32/133 (24%), Positives = 61/133 (45%)
Frame = +3
Query: 237 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 416
I+ T+GP++ + + ++ V R+N SH S + R+ E++ S
Sbjct: 5 IVATLGPSTDRLPDITALLSKVHGV-RINMSHASPSEVEARVNAVRKYEET------SGR 57
Query: 417 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 596
+AI D +GP +RTGL+ +++ G + S EKG+ + V +
Sbjct: 58 YIAIIADLRGPSVRTGLMR-----PLQITAGARV----SFKLAEKGDG-FVPVPRREFFE 107
Query: 597 VVKPGNRIFIDDG 635
V++ G+ + + DG
Sbjct: 108 VIEEGDEVLMLDG 120
>UniRef50_A5NL17 Cluster: ATP-dependent Clp protease, ATP-binding
subunit ClpA; n=1; Shewanella baltica OS223|Rep:
ATP-dependent Clp protease, ATP-binding subunit ClpA -
Shewanella baltica OS223
Length = 66
Score = 34.3 bits (75), Expect = 2.6
Identities = 20/51 (39%), Positives = 29/51 (56%), Gaps = 4/51 (7%)
Frame = +3
Query: 378 AEKSYSAKLGS-PFSLAIALDTKGP---EIRTGLLEGGGSAEVELKKGETI 518
AEK Y +G+ P + + K P EI G+LE GG A V++K+GE +
Sbjct: 3 AEKGYDKNMGARPMARVVTELIKRPLADEILFGVLESGGVAHVDVKEGELV 53
>UniRef50_Q8EYH8 Cluster: MutS-like mismatch repair protein,
ATPases; n=4; Leptospira|Rep: MutS-like mismatch repair
protein, ATPases - Leptospira interrogans
Length = 610
Score = 33.5 bits (73), Expect = 4.6
Identities = 49/171 (28%), Positives = 73/171 (42%), Gaps = 22/171 (12%)
Frame = +3
Query: 192 GLDIDSKSSYIRLSGIICTIG------PASR-NVAVLEKMMETGMNVARMNFSHGSHEYH 350
G ++ K++Y+R G+ + PAS+ ++ VL+ + T M N G ++
Sbjct: 441 GSNMSGKTTYLRTIGVASILSMAGGPVPASKFSLPVLK--IHTSMR-NEDNLEEGISFFY 497
Query: 351 AETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTT 530
AE +R E K K S L + KG R L G + ELKK TI T
Sbjct: 498 AE-VRRLSEIVKKIRDKNSSHLVLLDEI-LKGTNTRERSLACKGILK-ELKKNRTIVFVT 554
Query: 531 SSD-------------YQEKGNADTIYVDYKNITNVVKPGN--RIFIDDGL 638
S D +QE+ T+Y DYK +V+ N RI + +GL
Sbjct: 555 SHDLELAKVEGVILKHFQEEVLDGTMYFDYKIREGLVETSNALRILVQEGL 605
>UniRef50_Q8DLH6 Cluster: Pyruvate kinase; n=2; Synechococcus|Rep:
Pyruvate kinase - Synechococcus elongatus
(Thermosynechococcus elongatus)
Length = 506
Score = 33.5 bits (73), Expect = 4.6
Identities = 32/116 (27%), Positives = 48/116 (41%)
Frame = +3
Query: 288 MMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGL 467
++ GMN AR+N +H I + R A S G P I +D GP+ R
Sbjct: 160 LLRKGMNCARVNCAHDDPATWEAMIEHLRAA----SHITGQP--CKILMDLGGPKPRIAD 213
Query: 468 LEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDG 635
+ V + G+ ++LTT E G I ++ G R++IDDG
Sbjct: 214 I---FPETVRVHSGDRLRLTTEI-CPEGGEIPQFTCSLPEIVPQLEVGQRVWIDDG 265
>UniRef50_Q2AHN9 Cluster: Radical SAM; n=1; Halothermothrix orenii H
168|Rep: Radical SAM - Halothermothrix orenii H 168
Length = 231
Score = 33.5 bits (73), Expect = 4.6
Identities = 22/72 (30%), Positives = 33/72 (45%), Gaps = 3/72 (4%)
Frame = +3
Query: 426 IALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIY---VDYKNITN 596
IA+D K P R GLL G ++K+ I L ++ DY+ + Y D I
Sbjct: 120 IAMDIKAPFSRYGLLAGSSKYNNQIKESINILLNSNIDYEFRTTVIPGYHTENDLIKIAE 179
Query: 597 VVKPGNRIFIDD 632
++K R FI +
Sbjct: 180 LIKGAGRYFIQN 191
>UniRef50_Q1DYT2 Cluster: Putative uncharacterized protein; n=1;
Coccidioides immitis|Rep: Putative uncharacterized
protein - Coccidioides immitis
Length = 893
Score = 33.1 bits (72), Expect = 6.0
Identities = 19/46 (41%), Positives = 24/46 (52%), Gaps = 2/46 (4%)
Frame = -2
Query: 275 SYITGCRSNSTDYSG--ETDVRRLGVNVETAHMLELGADVGDCGLF 144
SYI G ++ + SG E DVRR G + ELGAD C +F
Sbjct: 229 SYIHGAETDEEEDSGFTEADVRRWGHEEVAERLRELGADPKHCEIF 274
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 626,156,730
Number of Sequences: 1657284
Number of extensions: 12089795
Number of successful extensions: 40287
Number of sequences better than 10.0: 158
Number of HSP's better than 10.0 without gapping: 38785
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 40122
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 49586781480
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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