Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmte17f02
(719 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC022515-1|AAH22515.1| 367|Homo sapiens testis-specific serine ... 161 2e-39
AY028964-1|AAK27734.1| 367|Homo sapiens testis-specific serine/... 161 2e-39
AB284522-1|BAF41973.1| 367|Homo sapiens testis-specific serine ... 161 2e-39
AY461663-1|AAS17971.1| 328|Homo sapiens testis-specific serine ... 158 2e-38
BC035354-1|AAH35354.1| 268|Homo sapiens testis-specific serine ... 156 9e-38
AY048701-1|AAL02128.1| 268|Homo sapiens TSSK3 protein. 156 9e-38
AL109945-4|CAI22888.1| 268|Homo sapiens testis-specific serine ... 156 9e-38
AF296450-1|AAK97141.1| 268|Homo sapiens testis-specific serine/... 156 9e-38
CR456587-1|CAG30473.1| 358|Homo sapiens STK22A protein. 154 3e-37
BC037781-1|AAH37781.1| 358|Homo sapiens testis-specific serine ... 154 3e-37
AF362953-1|AAK98531.1| 358|Homo sapiens testis specific serine/... 154 3e-37
AB284523-1|BAF41974.1| 358|Homo sapiens testis-specific serine ... 154 3e-37
AK131042-1|BAC85482.1| 338|Homo sapiens protein ( Homo sapiens ... 148 2e-35
AY120867-1|AAM55491.1| 752|Homo sapiens MAP/microtubule affinit... 137 4e-32
AY057448-1|AAL23683.1| 752|Homo sapiens MARK4 serine/threonine ... 137 4e-32
AK075272-1|BAC11510.1| 752|Homo sapiens protein ( Homo sapiens ... 137 4e-32
AB058763-1|BAB47489.1| 689|Homo sapiens KIAA1860 protein protein. 137 4e-32
BC014611-1|AAH14611.1| 273|Homo sapiens testis-specific serine ... 136 6e-32
AK172841-1|BAD18805.1| 406|Homo sapiens protein ( Homo sapiens ... 136 6e-32
AF329483-1|AAK48827.1| 273|Homo sapiens serine/threonine protei... 136 6e-32
BC128510-1|AAI28511.1| 1203|Homo sapiens KIAA0999 protein protein. 135 1e-31
BC038504-1|AAH38504.1| 783|Homo sapiens SNF1-like kinase protein. 135 1e-31
AK131076-1|BAC85126.1| 764|Homo sapiens FLJ00263 protein protein. 135 1e-31
AB047786-1|BAD74070.1| 783|Homo sapiens serine/threonine protei... 135 1e-31
AB023216-1|BAA76843.2| 1371|Homo sapiens KIAA0999 protein protein. 135 1e-31
BC084540-1|AAH84540.1| 724|Homo sapiens MAP/microtubule affinit... 135 2e-31
BC008771-1|AAH08771.2| 778|Homo sapiens MARK2 protein protein. 135 2e-31
AB188493-1|BAD37141.1| 719|Homo sapiens serine/threonine kinase... 135 2e-31
AB088047-1|BAC03375.1| 752|Homo sapiens microtubule affinity-re... 135 2e-31
AB049127-1|BAB39380.1| 688|Homo sapiens MAP/microtubule affinit... 135 2e-31
BC117183-1|AAI17184.1| 926|Homo sapiens SNF1-like kinase 2 prot... 134 2e-31
BC113459-1|AAI13460.1| 926|Homo sapiens SNF1-like kinase 2 prot... 134 2e-31
AB084424-1|BAB91442.1| 346|Homo sapiens KIAA0781 protein protein. 134 2e-31
AB018324-1|BAA34501.3| 950|Homo sapiens KIAA0781 protein protein. 134 2e-31
X97630-1|CAA66229.1| 745|Homo sapiens serine/threonine protein ... 134 4e-31
BT007342-1|AAP36006.1| 755|Homo sapiens MAP/microtubule affinit... 134 4e-31
AF387638-1|AAK82368.1| 691|Homo sapiens Ser/Thr protein kinase ... 134 4e-31
BC114478-1|AAI14479.1| 795|Homo sapiens MARK1 protein protein. 133 7e-31
BC113869-1|AAI13870.1| 795|Homo sapiens MARK1 protein protein. 133 7e-31
AL592406-3|CAH72463.1| 795|Homo sapiens MAP/microtubule affinit... 133 7e-31
AF154845-1|AAF72103.1| 795|Homo sapiens MARK protein. 133 7e-31
U64205-1|AAC15093.1| 729|Homo sapiens Cdc25C associated protein... 132 9e-31
M80359-1|AAA59991.1| 713|Homo sapiens protein p78 protein. 132 9e-31
BC024773-1|AAH24773.1| 729|Homo sapiens MAP/microtubule affinit... 132 9e-31
AF465413-1|AAL69982.1| 753|Homo sapiens MAP/microtubule affinit... 132 9e-31
AF387637-1|AAK82367.1| 744|Homo sapiens Ser/Thr protein kinase ... 132 9e-31
AP001751-1|BAA95536.1| 786|Homo sapiens SNF1LK protein. 129 9e-30
AB011109-1|BAA25463.2| 698|Homo sapiens KIAA0537 protein protein. 126 1e-28
BC121188-1|AAI21189.1| 185|Homo sapiens KIAA0999 protein protein. 125 1e-28
AC005581-1|AAC33487.1| 462|Homo sapiens R31237_1, partial CDS p... 73 9e-28
BC037303-1|AAH37303.1| 550|Homo sapiens PRKAA1 protein protein. 121 2e-27
BC012622-1|AAH12622.1| 207|Homo sapiens PRKAA1 protein protein. 121 2e-27
AB022017-1|BAA36547.1| 550|Homo sapiens AMP-activated protein k... 121 2e-27
BC017306-1|AAH17306.1| 628|Homo sapiens NUAK family, SNF1-like ... 120 7e-27
AK074830-1|BAC11234.1| 628|Homo sapiens protein ( Homo sapiens ... 120 7e-27
U06454-1|AAA64745.1| 552|Homo sapiens AMP-activated protein kin... 118 2e-26
BC069823-1|AAH69823.1| 552|Homo sapiens AMP-activated protein k... 118 2e-26
BC069740-1|AAH69740.1| 552|Homo sapiens AMP-activated protein k... 118 2e-26
BC069680-1|AAH69680.1| 552|Homo sapiens protein kinase, AMP-act... 118 2e-26
AL035705-2|CAC17574.2| 552|Homo sapiens protein kinase, AMP-act... 118 2e-26
AJ271722-1|CAB71146.1| 714|Homo sapiens putative serine/threoni... 118 3e-26
EF056019-1|ABK30810.1| 552|Homo sapiens AMP-activated alpha 2 s... 116 9e-26
AF054621-1|AAC25955.1| 309|Homo sapiens serine/threonine kinase... 115 2e-25
AB017332-1|BAA76292.1| 309|Homo sapiens Aurora/Ipl1-related kin... 115 2e-25
BC075064-1|AAH75064.2| 275|Homo sapiens AURKC protein protein. 113 6e-25
AY714054-1|AAU04399.1| 306|Homo sapiens aurora-C protein. 113 6e-25
AY661554-1|AAT64422.1| 290|Homo sapiens aurora/Ipl1-related kin... 113 6e-25
AF059681-1|AAC77369.1| 275|Homo sapiens serine/threonine kinase... 112 1e-24
U22456-1|AAA64850.1| 174|Homo sapiens AMP-activated protein kin... 110 4e-24
AF159295-1|AAD48007.1| 752|Homo sapiens serine/threonine protei... 110 6e-24
D79997-1|BAA11492.2| 656|Homo sapiens KIAA0175 protein. 107 4e-23
BC014039-1|AAH14039.1| 651|Homo sapiens maternal embryonic leuc... 107 4e-23
AL442063-1|CAI16995.2| 651|Homo sapiens maternal embryonic leuc... 107 4e-23
AL354932-1|CAI11034.2| 651|Homo sapiens maternal embryonic leuc... 107 4e-23
AK222811-1|BAD96531.1| 651|Homo sapiens maternal embryonic leuc... 107 4e-23
BC048980-1|AAH48980.1| 574|Homo sapiens protein kinase, AMP-act... 107 5e-23
D84212-1|BAA23592.1| 402|Homo sapiens aurora/IPL1-related kinas... 105 1e-22
BT019534-1|AAV38341.1| 344|Homo sapiens serine/threonine kinase... 105 2e-22
BC080581-1|AAH80581.1| 344|Homo sapiens aurora kinase B protein. 105 2e-22
BC009751-1|AAH09751.1| 344|Homo sapiens aurora kinase B protein. 105 2e-22
BC000442-1|AAH00442.3| 344|Homo sapiens aurora kinase B protein. 105 2e-22
AF008552-1|AAC12709.1| 344|Homo sapiens aurora-related kinase 2... 105 2e-22
AB011450-1|BAA32136.1| 344|Homo sapiens aurora and IPL1-like mi... 105 2e-22
AB011446-1|BAA82709.1| 343|Homo sapiens Aik2 protein. 105 2e-22
BC031231-1|AAH31231.1| 514|Homo sapiens serine/threonine kinase... 105 2e-22
AK093251-1|BAC04109.1| 514|Homo sapiens protein ( Homo sapiens ... 105 2e-22
AJ303380-1|CAC29064.1| 514|Homo sapiens serine/threonine kinase... 105 2e-22
AY505124-1|AAS86442.1| 778|Homo sapiens protein kinase SAD-B pr... 104 4e-22
AY458602-1|AAS10354.1| 778|Homo sapiens SAD1 kinase protein. 104 4e-22
AF479827-1|AAL87698.1| 778|Homo sapiens protein kinase-like pro... 104 4e-22
AF479826-1|AAL87697.1| 794|Homo sapiens putative serine/threoni... 104 4e-22
BC036422-1|AAH36422.1| 436|Homo sapiens hypothetical protein MG... 103 5e-22
BC013300-1|AAH13300.2| 371|Homo sapiens AURKB protein protein. 103 6e-22
AY505125-1|AAS86443.1| 696|Homo sapiens protein kinase SAD-A pr... 103 6e-22
AY166857-1|AAN87839.1| 668|Homo sapiens serine/threonine protei... 103 6e-22
AF533880-1|AAP97727.1| 674|Homo sapiens putative serine/threoni... 103 6e-22
AF533879-1|AAP97726.1| 736|Homo sapiens putative serine/threoni... 103 6e-22
AF533878-1|AAP97725.1| 674|Homo sapiens putative serine/threoni... 103 6e-22
AF533877-1|AAP97724.1| 674|Homo sapiens putative serine/threoni... 103 6e-22
AF533876-1|AAP97723.1| 668|Homo sapiens putative serine/threoni... 103 6e-22
AF004022-1|AAB65786.1| 347|Homo sapiens protein kinase protein. 103 8e-22
BC027464-1|AAH27464.1| 403|Homo sapiens aurora kinase A protein. 102 1e-21
BC006423-1|AAH06423.1| 403|Homo sapiens aurora kinase A protein. 102 1e-21
BC002499-1|AAH02499.1| 403|Homo sapiens AURKA protein protein. 102 1e-21
BC001280-1|AAH01280.1| 403|Homo sapiens aurora kinase A protein. 102 1e-21
AL121914-4|CAM45838.1| 347|Homo sapiens aurora kinase A protein. 102 1e-21
AL121914-3|CAC12717.1| 403|Homo sapiens aurora kinase A protein. 102 1e-21
AF195947-1|AAF29508.1| 403|Homo sapiens STK15 serine/threonine ... 102 1e-21
AF011468-1|AAC63902.1| 403|Homo sapiens serine/threonine kinase... 102 1e-21
AF008551-1|AAC12708.1| 403|Homo sapiens aurora-related kinase 1... 102 1e-21
Y15056-1|CAA75341.1| 556|Homo sapiens PkB kinase protein. 101 2e-21
CR536517-1|CAG38755.1| 556|Homo sapiens PDPK1 protein. 101 2e-21
BC012103-1|AAH12103.1| 556|Homo sapiens 3-phosphoinositide depe... 101 2e-21
AK027302-1|BAB55026.1| 208|Homo sapiens protein ( Homo sapiens ... 101 2e-21
AF017995-1|AAC51825.1| 556|Homo sapiens 3-phosphoinositide depe... 101 2e-21
AC005591-1|AAC33797.1| 367|Homo sapiens PkB-like protein. 101 2e-21
AB209835-1|BAD93072.1| 492|Homo sapiens 3-phosphoinositide depe... 101 2e-21
D43636-1|BAA07744.2| 766|Homo sapiens KIAA0096 protein. 101 3e-21
BC071567-1|AAH71567.1| 765|Homo sapiens SNRK protein protein. 101 3e-21
AK000231-1|BAA91023.1| 244|Homo sapiens protein ( Homo sapiens ... 101 3e-21
AF015254-1|AAC98891.1| 347|Homo sapiens serine/threonine kinase... 101 3e-21
AK222581-1|BAD96301.1| 556|Homo sapiens 3-phosphoinositide depe... 100 5e-21
AJ785968-1|CAH05056.1| 396|Homo sapiens PDPK2 protein protein. 100 5e-21
AF226044-1|AAF86944.1| 765|Homo sapiens HSNFRK protein. 100 5e-21
BC111088-1|AAI11089.1| 252|Homo sapiens TSSK4 protein protein. 100 1e-20
BC026158-1|AAH26158.1| 1315|Homo sapiens serine/threonine kinase... 98 2e-20
AF200815-1|AAF97028.1| 1315|Homo sapiens FUSED serine/threonine ... 98 2e-20
AB033104-1|BAA86592.1| 1311|Homo sapiens KIAA1278 protein protein. 98 2e-20
AK131534-1|BAD18671.1| 766|Homo sapiens protein ( Homo sapiens ... 97 7e-20
BC017575-1|AAH17575.1| 476|Homo sapiens CHK1 checkpoint homolog... 95 2e-19
BC004202-1|AAH04202.1| 476|Homo sapiens CHEK1 protein protein. 95 2e-19
AF527555-1|AAM78553.1| 476|Homo sapiens CHK1 checkpoint homolog... 95 2e-19
AF032874-1|AAB88852.1| 476|Homo sapiens protein kinase protein. 95 2e-19
AF016582-1|AAC51736.1| 476|Homo sapiens Chk1 protein. 95 2e-19
AB032387-1|BAA84577.1| 476|Homo sapiens checkpoint kinase protein. 95 2e-19
BC041799-1|AAH41799.1| 592|Homo sapiens CDKL3 protein protein. 95 2e-19
AF130372-1|AAF36509.1| 455|Homo sapiens serine-threonine protei... 95 2e-19
AB051552-1|BAB21856.1| 608|Homo sapiens KIAA1765 protein protein. 94 4e-19
AF045458-1|AAC32326.1| 1050|Homo sapiens serine/threonine kinase... 94 5e-19
AB018265-1|BAA34442.2| 1066|Homo sapiens KIAA0722 protein protein. 94 5e-19
AL834498-1|CAD39156.1| 716|Homo sapiens hypothetical protein pr... 93 7e-19
AL121914-5|CAI19324.1| 271|Homo sapiens aurora kinase A protein. 93 7e-19
AC093748-1|AAY40983.1| 443|Homo sapiens unknown protein. 93 7e-19
AB209181-1|BAD92418.1| 796|Homo sapiens Hypothetical protein DK... 93 7e-19
AL390029-2|CAI15721.1| 740|Homo sapiens doublecortin and CaM ki... 93 9e-19
AL390029-1|CAI15720.1| 729|Homo sapiens doublecortin and CaM ki... 93 9e-19
AL160392-2|CAH70261.1| 740|Homo sapiens doublecortin and CaM ki... 93 9e-19
AL160392-1|CAH70262.1| 729|Homo sapiens doublecortin and CaM ki... 93 9e-19
AL157760-4|CAH70170.1| 433|Homo sapiens doublecortin and CaM ki... 93 9e-19
AL157760-2|CAH70167.1| 740|Homo sapiens doublecortin and CaM ki... 93 9e-19
AL157760-1|CAH70168.1| 729|Homo sapiens doublecortin and CaM ki... 93 9e-19
AL157694-2|CAH70656.1| 740|Homo sapiens doublecortin and CaM ki... 93 9e-19
AL157694-1|CAH70657.1| 729|Homo sapiens doublecortin and CaM ki... 93 9e-19
AB002367-1|BAA20824.2| 794|Homo sapiens KIAA0369 protein. 93 9e-19
Z92542-3|CAI42485.1| 1030|Homo sapiens cyclin-dependent kinase-l... 91 3e-18
Y15057-1|CAA75342.1| 1030|Homo sapiens STK9 protein protein. 91 3e-18
AY217744-1|AAO64440.1| 1030|Homo sapiens serine/threonine kinase... 91 3e-18
AL109798-1|CAI41159.1| 1030|Homo sapiens cyclin-dependent kinase... 91 3e-18
U35146-1|AAC50918.1| 493|Homo sapiens p56 KKIAMRE protein kinas... 91 4e-18
BC093981-1|AAH93981.1| 493|Homo sapiens cyclin-dependent kinase... 91 4e-18
BC093646-1|AAH93646.1| 493|Homo sapiens cyclin-dependent kinase... 91 4e-18
AK058166-1|BAB71697.1| 128|Homo sapiens protein ( Homo sapiens ... 91 4e-18
X66358-1|CAA47002.1| 358|Homo sapiens serine/threonine protein ... 90 8e-18
U56998-1|AAC50637.1| 607|Homo sapiens putative serine/threonine... 90 8e-18
BC127622-1|AAI27623.1| 596|Homo sapiens myosin light chain kina... 90 8e-18
BC104977-1|AAI04978.1| 358|Homo sapiens cyclin-dependent kinase... 90 8e-18
BC092413-1|AAH92413.1| 596|Homo sapiens myosin light chain kina... 90 8e-18
BC069627-1|AAH69627.1| 596|Homo sapiens skeletal myosin light c... 90 8e-18
BC013899-1|AAH13899.1| 646|Homo sapiens polo-like kinase 3 (Dro... 90 8e-18
AY764184-1|AAU88146.1| 646|Homo sapiens polo-like kinase 3 (Dro... 90 8e-18
AY525548-1|AAS00095.1| 358|Homo sapiens cyclin-dependent kinase... 90 8e-18
AL592166-11|CAI13006.1| 646|Homo sapiens polo-like kinase 3 (Dr... 90 8e-18
AL160175-10|CAC10006.1| 596|Homo sapiens myosin light chain kin... 90 8e-18
AJ272502-1|CAC81354.1| 596|Homo sapiens skeletal muscle-specifi... 90 8e-18
AF325549-1|AAK15494.1| 596|Homo sapiens skeletal myosin light c... 90 8e-18
AB209875-1|BAD93112.1| 621|Homo sapiens polo-like kinase 3 vari... 90 8e-18
AJ293866-1|CAC10659.1| 646|Homo sapiens FNK serine/threonine pr... 89 1e-17
U24153-1|AAA65442.1| 525|Homo sapiens p21-activated protein kin... 89 1e-17
BC056423-1|AAH56423.1| 214|Homo sapiens ULK3 protein protein. 89 1e-17
BC036117-1|AAH36117.1| 214|Homo sapiens ULK3 protein protein. 89 1e-17
AB183427-1|BAF73615.1| 619|Homo sapiens maternal embryonic leuc... 89 1e-17
CR456418-1|CAG30304.1| 586|Homo sapiens CHEK2 protein. 89 2e-17
BC004207-1|AAH04207.1| 543|Homo sapiens CHK2 checkpoint homolog... 89 2e-17
AY800241-1|AAV41895.1| 543|Homo sapiens CHK2 checkpoint homolog... 89 2e-17
AY574904-1|AAT81413.1| 510|Homo sapiens regulated in COPD kinas... 89 2e-17
AY551303-1|AAS58464.1| 452|Homo sapiens protein kinase Chk2 tra... 89 2e-17
AY551297-1|AAS58458.1| 586|Homo sapiens protein kinase Chk2 tra... 89 2e-17
AL121825-1|CAH73823.1| 543|Homo sapiens CHK2 checkpoint homolog... 89 2e-17
AL117330-1|CAH73875.1| 543|Homo sapiens CHK2 checkpoint homolog... 89 2e-17
AJ131197-1|CAA10319.1| 543|Homo sapiens protein kinase protein. 89 2e-17
AF174135-1|AAD48504.1| 543|Homo sapiens protein kinase CHK2 pro... 89 2e-17
AF096279-1|AAD11784.1| 543|Homo sapiens HuCds1 kinase protein. 89 2e-17
AF086904-1|AAC83693.1| 543|Homo sapiens protein kinase Chk2 pro... 89 2e-17
AB058714-1|BAB47440.1| 715|Homo sapiens KIAA1811 protein protein. 88 3e-17
AB006972-1|BAB69958.1| 970|Homo sapiens Sak protein. 88 3e-17
Y13115-1|CAA73575.1| 970|Homo sapiens serine/threonine protein ... 88 3e-17
BC036023-1|AAH36023.1| 970|Homo sapiens polo-like kinase 4 (Dro... 88 3e-17
BC013879-1|AAH13879.1| 685|Homo sapiens polo-like kinase 2 (Dro... 88 3e-17
AK131198-1|BAD18393.1| 706|Homo sapiens protein ( Homo sapiens ... 88 3e-17
AK098163-1|BAC05247.1| 372|Homo sapiens protein ( Homo sapiens ... 88 3e-17
AF223574-1|AAF62897.1| 685|Homo sapiens serum-inducible kinase ... 88 3e-17
AF059617-1|AAC14573.1| 685|Homo sapiens serum-inducible kinase ... 88 3e-17
U63333-1|AAB05809.1| 433|Homo sapiens serine/threonine protein ... 87 5e-17
BC019334-1|AAH19334.1| 433|Homo sapiens serine/threonine kinase... 87 5e-17
BC007981-1|AAH07981.1| 433|Homo sapiens serine/threonine kinase... 87 5e-17
AF217978-1|AAG17221.1| 433|Homo sapiens unknown protein. 87 5e-17
AF055327-1|AAC15742.1| 433|Homo sapiens Peutz-Jeghers syndrome ... 87 5e-17
AF035625-1|AAC39527.1| 433|Homo sapiens serine threonine kinase... 87 5e-17
AF032986-1|AAB97833.1| 433|Homo sapiens serine threonine kinase... 87 5e-17
AB209553-1|BAD92790.1| 337|Homo sapiens serine/threonine protei... 87 5e-17
BC034988-1|AAH34988.1| 1036|Homo sapiens ULK2 protein protein. 87 6e-17
AB014523-1|BAA31598.2| 1100|Homo sapiens KIAA0623 protein protein. 87 6e-17
AY574902-1|AAT81411.1| 1215|Homo sapiens regulated in COPD kinas... 87 8e-17
AY574901-1|AAT81410.1| 1328|Homo sapiens regulated in COPD kinas... 87 8e-17
EF644172-1|ABR45718.1| 433|Homo sapiens polarization-related pr... 85 2e-16
AF217975-1|AAG17218.1| 322|Homo sapiens unknown protein. 85 2e-16
AF090421-1|AAC69577.1| 809|Homo sapiens ribosome S6 protein kin... 85 2e-16
BC019916-1|AAH19916.2| 506|Homo sapiens NIMA (never in mitosis ... 85 2e-16
AL139082-7|CAI12895.1| 507|Homo sapiens NIMA (never in mitosis ... 85 2e-16
AK131359-1|BAD18511.1| 510|Homo sapiens protein ( Homo sapiens ... 85 2e-16
AF080000-1|AAD23915.1| 802|Homo sapiens RSK-like protein kinase... 85 3e-16
AF074393-1|AAC31171.1| 802|Homo sapiens nuclear mitogen- and st... 85 3e-16
Y15801-1|CAA75792.1| 277|Homo sapiens protein kinase protein. 84 4e-16
Y13927-1|CAA74244.1| 277|Homo sapiens protein kinase protein. 84 4e-16
BC074852-1|AAH74852.1| 277|Homo sapiens protein kinase, Y-linke... 84 4e-16
BC074851-1|AAH74851.1| 277|Homo sapiens protein kinase, Y-linke... 84 4e-16
BC035745-1|AAH35745.1| 385|Homo sapiens calcium/calmodulin-depe... 84 6e-16
BC022558-1|AAH22558.1| 344|Homo sapiens CAMK2D protein protein. 84 6e-16
AL731559-2|CAI14675.1| 385|Homo sapiens calcium/calmodulin-depe... 84 6e-16
AL731559-1|CAI14674.1| 357|Homo sapiens calcium/calmodulin-depe... 84 6e-16
AL512783-2|CAH74036.1| 385|Homo sapiens calcium/calmodulin-depe... 84 6e-16
AL512783-1|CAH74035.1| 357|Homo sapiens calcium/calmodulin-depe... 84 6e-16
AL512284-2|CAH71694.1| 385|Homo sapiens calcium/calmodulin-depe... 84 6e-16
AL512284-1|CAH71693.1| 357|Homo sapiens calcium/calmodulin-depe... 84 6e-16
AL391314-2|CAI14410.1| 385|Homo sapiens calcium/calmodulin-depe... 84 6e-16
AL391314-1|CAI14409.1| 357|Homo sapiens calcium/calmodulin-depe... 84 6e-16
AF286366-1|AAG00534.1| 357|Homo sapiens CamKI-like protein kina... 84 6e-16
AB081726-1|BAC19846.1| 385|Homo sapiens CaM-kinase I delta prot... 84 6e-16
BC114491-1|AAI14492.1| 1189|Homo sapiens NEK1 protein protein. 83 7e-16
BC040457-1|AAH40457.1| 478|Homo sapiens calcium/calmodulin-depe... 83 7e-16
BC015147-1|AAH15147.1| 403|Homo sapiens Unknown (protein for IM... 83 7e-16
AF145711-1|AAD30559.1| 489|Homo sapiens calcium/calmodulin-depe... 83 7e-16
AF145710-1|AAD30558.1| 478|Homo sapiens calcium/calmodulin-depe... 83 7e-16
AF091486-1|AAD55815.1| 478|Homo sapiens calmodulin-dependent pr... 83 7e-16
AB067488-1|BAB67794.1| 1265|Homo sapiens KIAA1901 protein protein. 83 7e-16
AB023185-1|BAA76812.1| 527|Homo sapiens KIAA0968 protein protein. 83 7e-16
U23460-1|AAC99802.1| 664|Homo sapiens proline rich calmodulin-d... 83 1e-15
L41816-1|AAA99458.1| 370|Homo sapiens cam kinase I protein. 83 1e-15
BC106755-1|AAI06756.1| 370|Homo sapiens calcium/calmodulin-depe... 83 1e-15
BC106754-1|AAI06755.1| 370|Homo sapiens calcium/calmodulin-depe... 83 1e-15
BC019070-1|AAH19070.1| 503|Homo sapiens calcium/calmodulin-depe... 83 1e-15
AK222703-1|BAD96423.1| 542|Homo sapiens calcium/calmodulin-depe... 83 1e-15
AJ252238-1|CAB65122.1| 518|Homo sapiens calcium/calmodulin depe... 83 1e-15
AJ252237-1|CAB65121.1| 479|Homo sapiens calcium/calmodulin depe... 83 1e-15
AJ252236-1|CAB65120.1| 503|Homo sapiens calcium/calmodulin depe... 83 1e-15
AF140350-1|AAD42070.1| 449|Homo sapiens calcium/calmodulin-depe... 83 1e-15
AF083419-1|AAD42038.1| 517|Homo sapiens calcium/calmodulin-depe... 83 1e-15
AF081924-1|AAD42037.1| 492|Homo sapiens calcium/calmodulin-depe... 83 1e-15
AF081572-1|AAD42036.1| 503|Homo sapiens calcium/calmodulin-depe... 83 1e-15
AF078803-1|AAD42035.1| 542|Homo sapiens calcium/calmodulin-depe... 83 1e-15
U77129-1|AAB48435.1| 846|Homo sapiens KHS1 protein. 83 1e-15
BC063885-1|AAH63885.1| 708|Homo sapiens NIMA (never in mitosis ... 83 1e-15
BC036013-1|AAH36013.1| 846|Homo sapiens mitogen-activated prote... 83 1e-15
BC032784-1|AAH32784.1| 478|Homo sapiens calcium/calmodulin-depe... 83 1e-15
AY987011-1|AAX88806.1| 489|Homo sapiens calcium/calmodulin-depe... 83 1e-15
AL139082-5|CAI12892.2| 708|Homo sapiens NIMA (never in mitosis ... 83 1e-15
AJ252239-1|CAB65123.1| 243|Homo sapiens calcium/calmodulin depe... 83 1e-15
AB209288-1|BAD92525.1| 522|Homo sapiens calcium/calmodulin-depe... 83 1e-15
AB072828-1|BAC15599.1| 489|Homo sapiens NIMA-related protein ki... 83 1e-15
Y00272-1|CAA68376.1| 297|Homo sapiens protein ( Human cell cycl... 82 2e-15
X05360-1|CAA28963.1| 297|Homo sapiens protein ( Human CDC2 gene... 82 2e-15
U25975-1|AAA75468.1| 493|Homo sapiens hPAK65 protein. 82 2e-15
L07597-1|AAC82497.1| 735|Homo sapiens ribosomal protein S6 kina... 82 2e-15
BT007004-1|AAP35650.1| 297|Homo sapiens cell division cycle 2, ... 82 2e-15
BC107750-1|AAI07751.1| 225|Homo sapiens CDC2 protein protein. 82 2e-15
BC069613-1|AAH69613.1| 524|Homo sapiens p21-activated kinase 2 ... 82 2e-15
BC037268-1|AAH37268.1| 683|Homo sapiens protein kinase C, eta p... 82 2e-15
BC014966-1|AAH14966.1| 735|Homo sapiens ribosomal protein S6 ki... 82 2e-15
BC014563-1|AAH14563.1| 297|Homo sapiens cell division cycle 2, ... 82 2e-15
AL627313-6|CAI14649.1| 735|Homo sapiens ribosomal protein S6 ki... 82 2e-15
AL627313-4|CAI14647.1| 578|Homo sapiens ribosomal protein S6 ki... 82 2e-15
AF512554-1|AAM34793.1| 297|Homo sapiens cell division cycle 2, ... 82 2e-15
BC062616-1|AAH62616.1| 424|Homo sapiens protein serine kinase H... 82 2e-15
AL357774-2|CAI40843.1| 544|Homo sapiens p21 (CDKN1A)-activated ... 82 2e-15
AL357774-1|CAI40844.1| 559|Homo sapiens p21 (CDKN1A)-activated ... 82 2e-15
AL117326-3|CAI43167.1| 544|Homo sapiens p21 (CDKN1A)-activated ... 82 2e-15
AL117326-2|CAI43168.1| 559|Homo sapiens p21 (CDKN1A)-activated ... 82 2e-15
AL031117-6|CAI43157.1| 544|Homo sapiens p21 (CDKN1A)-activated ... 82 2e-15
AL031117-5|CAI43158.1| 559|Homo sapiens p21 (CDKN1A)-activated ... 82 2e-15
AJ272212-1|CAB91984.1| 424|Homo sapiens protein serine kinase p... 82 2e-15
AF155651-1|AAF67008.1| 544|Homo sapiens P21-activated kinase 3 ... 82 2e-15
AF068864-1|AAC36097.1| 544|Homo sapiens p21-activated kinase 3 ... 82 2e-15
AB102659-1|BAC81128.1| 559|Homo sapiens p21-activated kinase 3 ... 82 2e-15
X73458-1|CAA51837.1| 603|Homo sapiens protein kinase protein. 81 3e-15
M55284-1|AAA60100.1| 682|Homo sapiens protein kinase C-L protein. 81 3e-15
BC014846-1|AAH14846.1| 603|Homo sapiens polo-like kinase 1 (Dro... 81 3e-15
BC003002-1|AAH03002.1| 603|Homo sapiens polo-like kinase 1 (Dro... 81 3e-15
BC002369-1|AAH02369.1| 603|Homo sapiens polo-like kinase 1 (Dro... 81 3e-15
AJ006701-1|CAA07196.1| 603|Homo sapiens putative serine/threoni... 81 3e-15
AB084459-1|BAD93352.1| 247|Homo sapiens polo-like kinase 1 delt... 81 3e-15
Z29066-1|CAA82309.1| 445|Homo sapiens protein kinase protein. 81 4e-15
X85545-1|CAA59733.1| 358|Homo sapiens protein kinase protein. 81 4e-15
U11050-1|AAA19558.1| 445|Homo sapiens NIMA-like protein kinase ... 81 4e-15
BT019729-1|AAV38534.1| 445|Homo sapiens NIMA (never in mitosis ... 81 4e-15
BC065932-1|AAH65932.1| 214|Homo sapiens NEK2 protein protein. 81 4e-15
BC052807-1|AAH52807.1| 326|Homo sapiens NEK2 protein protein. 81 4e-15
BC043502-1|AAH43502.2| 445|Homo sapiens NIMA (never in mitosis ... 81 4e-15
BC041073-1|AAH41073.1| 358|Homo sapiens protein kinase, X-linke... 81 4e-15
BC030134-1|AAH30134.1| 816|Homo sapiens mitogen-activated prote... 81 4e-15
BC009963-1|AAH09963.1| 816|Homo sapiens mitogen-activated prote... 81 4e-15
AY534741-1|AAS38577.1| 533|Homo sapiens mitogen activated prote... 81 4e-15
AY045701-1|AAK92212.1| 384|Homo sapiens NEK2B protein kinase pr... 81 4e-15
AL356310-2|CAH72901.1| 445|Homo sapiens NIMA (never in mitosis ... 81 4e-15
AK223353-1|BAD97073.1| 445|Homo sapiens NIMA (never in mitosis ... 81 4e-15
AF071569-1|AAD20442.1| 499|Homo sapiens multifunctional calcium... 81 4e-15
AB209428-1|BAD92665.1| 279|Homo sapiens p21-activated kinase 2 ... 81 4e-15
AB020641-1|BAA74857.2| 453|Homo sapiens KIAA0834 protein protein. 81 4e-15
U24152-1|AAA65441.1| 545|Homo sapiens p21-activated protein kin... 81 5e-15
L19559-1|AAA36659.1| 603|Homo sapiens protein kinase protein. 81 5e-15
D86968-1|BAA13204.2| 1626|Homo sapiens KIAA0213 protein. 81 5e-15
BC146770-1|AAI46771.1| 1558|Homo sapiens mitogen-activated prote... 81 5e-15
BC114506-1|AAI14507.1| 370|Homo sapiens death-associated protei... 81 5e-15
BC109299-1|AAI09300.1| 545|Homo sapiens p21/Cdc42/Rac1-activate... 81 5e-15
BC109097-1|AAI09098.2| 795|Homo sapiens MLCK protein protein. 81 5e-15
BC032787-1|AAH32787.1| 476|Homo sapiens calcium/calmodulin-depe... 81 5e-15
AY355461-1|AAQ84219.1| 347|Homo sapiens MNK1-like kinase 1b pro... 81 5e-15
AY212935-1|AAP29964.1| 460|Homo sapiens CLICK III protein. 81 5e-15
AL596452-3|CAI41309.1| 1498|Homo sapiens mitogen-activated prote... 81 5e-15
AL596452-2|CAI41310.1| 1544|Homo sapiens mitogen-activated prote... 81 5e-15
AL591045-2|CAH70639.1| 1498|Homo sapiens mitogen-activated prote... 81 5e-15
AL591045-1|CAH70640.1| 1544|Homo sapiens mitogen-activated prote... 81 5e-15
AL139393-2|CAI20815.1| 1498|Homo sapiens mitogen-activated prote... 81 5e-15
AL139393-1|CAI20816.1| 1544|Homo sapiens mitogen-activated prote... 81 5e-15
AL136373-5|CAI14764.1| 424|Homo sapiens MAP kinase interacting ... 81 5e-15
AL109942-4|CAI21477.1| 1498|Homo sapiens mitogen-activated prote... 81 5e-15
AL109942-3|CAC12766.2| 1544|Homo sapiens mitogen-activated prote... 81 5e-15
AL049688-1|CAB41259.1| 481|Homo sapiens hypothetical protein pr... 81 5e-15
AL023754-3|CAI19991.1| 476|Homo sapiens calcium/calmodulin-depe... 81 5e-15
AL023754-2|CAI19990.1| 245|Homo sapiens calcium/calmodulin-depe... 81 5e-15
AJ247087-1|CAC42766.1| 795|Homo sapiens myosin light chain kina... 81 5e-15
AF428261-1|AAL28100.1| 476|Homo sapiens calcium/calmodulin-depe... 81 5e-15
AF071884-1|AAC24716.1| 553|Homo sapiens p21 activated kinase 1B... 81 5e-15
AF052941-1|AAC35001.1| 370|Homo sapiens DAP-kinase related prot... 81 5e-15
AF002715-1|AAB68804.1| 1607|Homo sapiens MAP kinase kinase kinas... 81 5e-15
AB018001-1|BAA88063.1| 370|Homo sapiens Death-associated protei... 81 5e-15
AB000409-1|BAA19885.1| 424|Homo sapiens MNK1 protein. 81 5e-15
Z15108-1|CAA78813.1| 584|Homo sapiens protein kinase C zeta pro... 80 7e-15
X58741-1|CAA41565.2| 348|Homo sapiens tyrosine kinase protein. 80 7e-15
U29727-1|AAA82933.1| 816|Homo sapiens BMK1 gamma kinase protein. 80 7e-15
U29726-1|AAA82932.1| 816|Homo sapiens BMK1 beta kinase protein. 80 7e-15
U29725-1|AAA82931.1| 816|Homo sapiens BMK1 alpha kinase protein. 80 7e-15
U25278-1|AAA81381.1| 815|Homo sapiens ERK5 protein. 80 7e-15
M95936-1|AAA58364.1| 481|Homo sapiens protein serine/threonine ... 80 7e-15
M77198-1|AAA36585.1| 520|Homo sapiens rac protein kinase-beta p... 80 7e-15
M16592-1|AAA52644.1| 505|Homo sapiens HCK protein. 80 7e-15
M16591-1|AAA52643.1| 505|Homo sapiens HCK protein. 80 7e-15
BT007082-1|AAP35745.1| 592|Homo sapiens protein kinase C, zeta ... 80 7e-15
BC120994-1|AAI20995.1| 481|Homo sapiens v-akt murine thymoma vi... 80 7e-15
BC114463-1|AAI14464.2| 526|Homo sapiens hemopoietic cell kinase... 80 7e-15
BC108931-1|AAI08932.2| 526|Homo sapiens hemopoietic cell kinase... 80 7e-15
BC108930-1|AAI08931.2| 526|Homo sapiens hemopoietic cell kinase... 80 7e-15
BC094847-1|AAH94847.2| 526|Homo sapiens hemopoietic cell kinase... 80 7e-15
BC032709-1|AAH32709.1| 344|Homo sapiens AKT2 protein protein. 80 7e-15
BC014435-1|AAH14435.2| 526|Homo sapiens hemopoietic cell kinase... 80 7e-15
BC014270-1|AAH14270.1| 592|Homo sapiens protein kinase C, zeta ... 80 7e-15
BC008058-1|AAH08058.1| 592|Homo sapiens protein kinase C, zeta ... 80 7e-15
AY994058-1|AAY44299.1| 254|Homo sapiens extracellular regulated... 80 7e-15
AL645703-1|CAI21535.1| 592|Homo sapiens protein kinase C, zeta ... 80 7e-15
AL590822-9|CAI12484.1| 592|Homo sapiens protein kinase C, zeta ... 80 7e-15
AL391845-5|CAI15438.1| 592|Homo sapiens protein kinase C, zeta ... 80 7e-15
AL353092-2|CAI19694.1| 505|Homo sapiens hemopoietic cell kinase... 80 7e-15
AL353092-1|CAI19695.1| 504|Homo sapiens hemopoietic cell kinase... 80 7e-15
AL049539-2|CAI22966.1| 505|Homo sapiens hemopoietic cell kinase... 80 7e-15
AL049539-1|CAI22967.1| 504|Homo sapiens hemopoietic cell kinase... 80 7e-15
AK026432-1|BAB15482.1| 505|Homo sapiens protein ( Homo sapiens ... 80 7e-15
L33881-1|AAB17011.1| 587|Homo sapiens protein kinase C iota pro... 80 9e-15
L18964-1|AAA60171.1| 587|Homo sapiens protein kinase C iota pro... 80 9e-15
BC022016-1|AAH22016.3| 587|Homo sapiens protein kinase C, iota ... 80 9e-15
X75932-1|CAA53536.1| 603|Homo sapiens Serine/Threonine protein ... 79 1e-14
U08316-1|AAA81952.1| 740|Homo sapiens insulin-stimulated protei... 79 1e-14
U01038-1|AAA56634.1| 603|Homo sapiens pLK protein. 79 1e-14
BC096303-1|AAH96303.1| 740|Homo sapiens ribosomal protein S6 ki... 79 1e-14
BC096302-1|AAH96302.1| 740|Homo sapiens ribosomal protein S6 ki... 79 1e-14
BC096301-1|AAH96301.1| 740|Homo sapiens ribosomal protein S6 ki... 79 1e-14
AY847283-1|AAW31760.1| 379|Homo sapiens cyclin-dependent kinase... 79 1e-14
AY845084-1|AAW30008.1| 315|Homo sapiens cyclin-dependent kinase... 79 1e-14
AL807772-3|CAI39687.1| 740|Homo sapiens ribosomal protein S6 ki... 79 1e-14
AL732366-2|CAI40548.1| 740|Homo sapiens ribosomal protein S6 ki... 79 1e-14
AK027493-1|BAB55152.1| 638|Homo sapiens protein ( Homo sapiens ... 79 1e-14
AF119833-1|AAG43234.1| 469|Homo sapiens serine/threonine protei... 79 1e-14
AF112472-1|AAD03744.1| 542|Homo sapiens calcium/calmodulin-depe... 79 1e-14
AF112471-1|AAD03743.1| 517|Homo sapiens calcium/calmodulin-depe... 79 1e-14
AB102662-1|BAC81131.1| 726|Homo sapiens RPS6KA3 protein. 79 1e-14
X05027-1|CAA28691.1| 507|Homo sapiens protein ( Human T cell-sp... 79 2e-14
L14283-1|AAA36488.1| 592|Homo sapiens protein kinase C zeta pro... 79 2e-14
BC126432-1|AAI26433.1| 454|Homo sapiens death-associated protei... 79 2e-14
BC126430-1|AAI26431.1| 454|Homo sapiens death-associated protei... 79 2e-14
BC113854-1|AAI13855.2| 504|Homo sapiens HCK protein protein. 79 2e-14
BC073140-1|AAH73140.1| 414|Homo sapiens MAP kinase interacting ... 79 2e-14
AL136373-4|CAI14763.1| 266|Homo sapiens MAP kinase interacting ... 79 2e-14
AF237776-1|AAG26337.1| 414|Homo sapiens MAP kinase-interacting ... 79 2e-14
AF237775-1|AAG26336.1| 465|Homo sapiens MAP kinase-interacting ... 79 2e-14
AF125532-1|AAF17226.1| 414|Homo sapiens map kinase-interacting ... 79 2e-14
AC007136-1|AAD21217.1| 472|Homo sapiens Putative map kinase int... 79 2e-14
AB208933-1|BAD92170.1| 806|Homo sapiens ribosomal protein S6 ki... 79 2e-14
AB022341-1|BAA81746.1| 454|Homo sapiens ZIP kinase protein. 79 2e-14
AB007144-1|BAA24955.1| 454|Homo sapiens ZIP-kinase protein. 79 2e-14
X14055-1|CAA32211.1| 509|Homo sapiens protein ( Human lymphocyt... 79 2e-14
X13529-1|CAA31884.1| 509|Homo sapiens protein ( Human lck mRNA ... 79 2e-14
U51120-1|AAC50590.1| 545|Homo sapiens PAK1 protein. 79 2e-14
L20321-1|AAA36658.1| 841|Homo sapiens protein serine/threonine ... 79 2e-14
BC063044-1|AAH63044.1| 781|Homo sapiens NEK4 protein protein. 79 2e-14
BC015515-1|AAH15515.1| 451|Homo sapiens Unknown (protein for IM... 79 2e-14
AL121991-3|CAI22320.1| 496|Homo sapiens lymphocyte-specific pro... 79 2e-14
AF228313-1|AAF34794.1| 496|Homo sapiens tyrosine kinase LCK pro... 79 2e-14
U07236-1|AAA18225.1| 512|Homo sapiens lymphocyte-specific prote... 78 3e-14
BT020098-1|AAV38901.1| 367|Homo sapiens serum/glucocorticoid re... 78 3e-14
BC024179-1|AAH24179.1| 719|Homo sapiens p21(CDKN1A)-activated k... 78 3e-14
AY065978-1|AAL40897.1| 544|Homo sapiens extracellular signal-re... 78 3e-14
AL353612-1|CAI23529.1| 719|Homo sapiens p21(CDKN1A)-activated k... 78 3e-14
AL135935-1|CAH71126.1| 719|Homo sapiens p21(CDKN1A)-activated k... 78 3e-14
AL031652-1|CAI42211.1| 719|Homo sapiens p21(CDKN1A)-activated k... 78 3e-14
AK074578-1|BAC11070.1| 426|Homo sapiens protein ( Homo sapiens ... 78 3e-14
AB040812-1|BAA94194.1| 719|Homo sapiens protein kinase PAK5 pro... 78 3e-14
AB033090-1|BAA86578.1| 753|Homo sapiens KIAA1264 protein protein. 78 3e-14
M34181-1|AAA60170.1| 351|Homo sapiens cAMP-dependent protein ki... 78 4e-14
DQ667174-1|ABG25919.1| 398|Homo sapiens protein kinase, cAMP-de... 78 4e-14
BC038807-1|AAH38807.1| 349|Homo sapiens ALS2CR7 protein protein. 78 4e-14
BC016285-1|AAH16285.1| 257|Homo sapiens protein kinase, cAMP-de... 78 4e-14
AL450063-11|CAI16854.1| 264|Homo sapiens protein kinase, cAMP-d... 78 4e-14
AL450063-10|CAI16853.1| 209|Homo sapiens protein kinase, cAMP-d... 78 4e-14
AL450063-9|CAI16852.1| 197|Homo sapiens protein kinase, cAMP-de... 78 4e-14
AL450063-8|CAI16851.1| 206|Homo sapiens protein kinase, cAMP-de... 78 4e-14
AL450063-7|CAI16850.1| 245|Homo sapiens protein kinase, cAMP-de... 78 4e-14
AL450063-6|CAI16849.1| 214|Homo sapiens protein kinase, cAMP-de... 78 4e-14
AL450063-3|CAI16846.1| 398|Homo sapiens protein kinase, cAMP-de... 78 4e-14
AL450063-2|CAI16845.1| 351|Homo sapiens protein kinase, cAMP-de... 78 4e-14
AL450063-1|CAI16844.1| 257|Homo sapiens protein kinase, cAMP-de... 78 4e-14
AL359504-2|CAI14541.1| 351|Homo sapiens protein kinase, cAMP-de... 78 4e-14
AL359504-1|CAI14540.1| 257|Homo sapiens protein kinase, cAMP-de... 78 4e-14
AC007242-1|AAX93182.1| 301|Homo sapiens unknown protein. 78 4e-14
AB209189-1|BAD92426.1| 365|Homo sapiens cAMP-dependent protein ... 78 4e-14
AB053308-1|BAB69017.1| 384|Homo sapiens ALS2CR7 protein. 78 4e-14
Z92868-1|CAB07437.1| 686|Homo sapiens cGMP-dependent protein ki... 77 5e-14
Z92867-1|CAB07436.1| 671|Homo sapiens cGMP-dependent protein ki... 77 5e-14
Y07512-1|CAA68810.1| 686|Homo sapiens protein ( Human mRNA for ... 77 5e-14
X76104-1|CAA53712.1| 1431|Homo sapiens DAP-kinase protein. 77 5e-14
U85755-1|AAD00575.1| 299|Homo sapiens serum-inducible kinase pr... 77 5e-14
U66064-1|AAB80848.1| 315|Homo sapiens calcium/calmodulin-depend... 77 5e-14
S76617-1|AAB33265.1| 505|Homo sapiens blk protein. 77 5e-14
D45864-1|BAA08297.1| 671|Homo sapiens cGMP-dependent protein ki... 77 5e-14
DQ436495-1|ABD96827.1| 1430|Homo sapiens death-associated protei... 77 5e-14
BT006935-1|AAP35581.1| 367|Homo sapiens death-associated protei... 77 5e-14
BC127090-1|AAI27091.1| 686|Homo sapiens protein kinase, cGMP-de... 77 5e-14
BC113660-1|AAI13661.1| 1430|Homo sapiens death-associated protei... 77 5e-14
BC032413-1|AAH32413.1| 505|Homo sapiens B lymphoid tyrosine kin... 77 5e-14
BC018703-1|AAH18703.1| 599|Homo sapiens Unknown (protein for IM... 77 5e-14
BC007371-1|AAH07371.1| 505|Homo sapiens B lymphoid tyrosine kin... 77 5e-14
AL928686-2|CAI40743.1| 686|Homo sapiens protein kinase, cGMP-de... 77 5e-14
AL928686-1|CAI40742.1| 659|Homo sapiens protein kinase, cGMP-de... 77 5e-14
AL731537-3|CAI17115.1| 686|Homo sapiens protein kinase, cGMP-de... 77 5e-14
AL731537-2|CAI17114.1| 659|Homo sapiens protein kinase, cGMP-de... 77 5e-14
AL713896-5|CAI13790.1| 529|Homo sapiens calcium/calmodulin-depe... 77 5e-14
AL713896-4|CAI13789.1| 495|Homo sapiens calcium/calmodulin-depe... 77 5e-14
AL713896-3|CAI13791.1| 527|Homo sapiens calcium/calmodulin-depe... 77 5e-14
AL713896-2|CAI13788.1| 516|Homo sapiens calcium/calmodulin-depe... 77 5e-14
AL596247-5|CAI13965.1| 529|Homo sapiens calcium/calmodulin-depe... 77 5e-14
AL596247-4|CAI13966.1| 495|Homo sapiens calcium/calmodulin-depe... 77 5e-14
AL596247-3|CAI13968.1| 527|Homo sapiens calcium/calmodulin-depe... 77 5e-14
AL596247-2|CAI13967.1| 516|Homo sapiens calcium/calmodulin-depe... 77 5e-14
AL591852-1|CAH71696.1| 1455|Homo sapiens death-associated protei... 77 5e-14
AL391378-2|CAI39626.1| 686|Homo sapiens protein kinase, cGMP-de... 77 5e-14
AL391378-1|CAI39625.1| 659|Homo sapiens protein kinase, cGMP-de... 77 5e-14
AL161787-1|CAH73544.1| 1455|Homo sapiens death-associated protei... 77 5e-14
AL160279-1|CAI16306.1| 1455|Homo sapiens death-associated protei... 77 5e-14
AL157399-2|CAI41305.1| 686|Homo sapiens protein kinase, cGMP-de... 77 5e-14
AL157399-1|CAI41304.1| 659|Homo sapiens protein kinase, cGMP-de... 77 5e-14
AF030403-1|AAD01901.1| 547|Homo sapiens Ste20-like protein kina... 77 5e-14
AB208871-1|BAD92108.1| 1433|Homo sapiens Hypothetical protein DK... 77 5e-14
X61037-1|CAA43372.1| 417|Homo sapiens human protein kinase B p... 77 6e-14
BC034511-1|AAH34511.1| 501|Homo sapiens PAK4 protein protein. 77 6e-14
BC034044-1|AAH34044.1| 527|Homo sapiens calcium/calmodulin-depe... 77 6e-14
BC025282-1|AAH25282.1| 591|Homo sapiens p21(CDKN1A)-activated k... 77 6e-14
BC020479-1|AAH20479.1| 466|Homo sapiens AKT3 protein protein. 77 6e-14
BC011368-1|AAH11368.1| 591|Homo sapiens p21(CDKN1A)-activated k... 77 6e-14
BC002921-1|AAH02921.1| 426|Homo sapiens p21(CDKN1A)-activated k... 77 6e-14
AY005799-1|AAF91073.1| 465|Homo sapiens protein kinase B gamma ... 77 6e-14
AL662889-3|CAH73073.1| 479|Homo sapiens v-akt murine thymoma vi... 77 6e-14
AL662889-2|CAH73072.1| 465|Homo sapiens v-akt murine thymoma vi... 77 6e-14
AL592151-2|CAH72892.1| 479|Homo sapiens v-akt murine thymoma vi... 77 6e-14
AL592151-1|CAH72891.1| 465|Homo sapiens v-akt murine thymoma vi... 77 6e-14
AL591721-2|CAH71867.1| 479|Homo sapiens v-akt murine thymoma vi... 77 6e-14
AL591721-1|CAH71866.1| 465|Homo sapiens v-akt murine thymoma vi... 77 6e-14
AK223561-1|BAD97281.1| 765|Homo sapiens ribosomal protein S6 ki... 77 6e-14
AJ245709-1|CAB53537.1| 479|Homo sapiens Akt-3 protein protein. 77 6e-14
AJ011855-1|CAA09820.1| 591|Homo sapiens PAK4 protein protein. 77 6e-14
AF135794-1|AAD24196.1| 479|Homo sapiens AKT3 protein kinase pro... 77 6e-14
AF124141-1|AAD29089.1| 479|Homo sapiens protein kinase B gamma ... 77 6e-14
AF085234-1|AAL40392.1| 479|Homo sapiens STK-2 protein. 77 6e-14
AF005046-1|AAD01210.1| 591|Homo sapiens serine/threonine kinase... 77 6e-14
>BC022515-1|AAH22515.1| 367|Homo sapiens testis-specific serine
kinase 1B protein.
Length = 367
Score = 161 bits (392), Expect = 2e-39
Identities = 79/154 (51%), Positives = 107/154 (69%), Gaps = 1/154 (0%)
Frame = +1
Query: 250 VLESHGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVK 429
VL+ GY+LG +G GSYA VK A S+R VAIKII + +AP D+L+KFLPREIE++
Sbjct: 6 VLKRRGYLLGINLGEGSYAKVKSAYSERLKFNVAIKIIDRKKAPADFLEKFLPREIEILA 65
Query: 430 GLKHENLIRFLQAIETTH-RVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVD 606
L H ++I+ + ET+H +VYIVME A G LL++I+ + E R+ F QL A+
Sbjct: 66 MLNHCSIIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGALHEDEARKKFHQLSLAIK 125
Query: 607 YCHERGVVHRDIKCENLLMDHGLNIKLSDFGFAR 708
YCH+ VVHRD+KC+NLL+D NIKLSDF F++
Sbjct: 126 YCHDLDVVHRDLKCDNLLLDKDFNIKLSDFSFSK 159
>AY028964-1|AAK27734.1| 367|Homo sapiens testis-specific
serine/threonine kinase 1 protein.
Length = 367
Score = 161 bits (392), Expect = 2e-39
Identities = 79/154 (51%), Positives = 107/154 (69%), Gaps = 1/154 (0%)
Frame = +1
Query: 250 VLESHGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVK 429
VL+ GY+LG +G GSYA VK A S+R VAIKII + +AP D+L+KFLPREIE++
Sbjct: 6 VLKRRGYLLGINLGEGSYAKVKSAYSERLKFNVAIKIIDRKKAPADFLEKFLPREIEILA 65
Query: 430 GLKHENLIRFLQAIETTH-RVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVD 606
L H ++I+ + ET+H +VYIVME A G LL++I+ + E R+ F QL A+
Sbjct: 66 MLNHCSIIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGALHEDEARKKFHQLSLAIK 125
Query: 607 YCHERGVVHRDIKCENLLMDHGLNIKLSDFGFAR 708
YCH+ VVHRD+KC+NLL+D NIKLSDF F++
Sbjct: 126 YCHDLDVVHRDLKCDNLLLDKDFNIKLSDFSFSK 159
>AB284522-1|BAF41973.1| 367|Homo sapiens testis-specific serine
kinase 1 protein.
Length = 367
Score = 161 bits (392), Expect = 2e-39
Identities = 79/154 (51%), Positives = 107/154 (69%), Gaps = 1/154 (0%)
Frame = +1
Query: 250 VLESHGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVK 429
VL+ GY+LG +G GSYA VK A S+R VAIKII + +AP D+L+KFLPREIE++
Sbjct: 6 VLKRRGYLLGINLGEGSYAKVKSAYSERLKFNVAIKIIDRKKAPADFLEKFLPREIEILA 65
Query: 430 GLKHENLIRFLQAIETTH-RVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVD 606
L H ++I+ + ET+H +VYIVME A G LL++I+ + E R+ F QL A+
Sbjct: 66 MLNHCSIIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGALHEDEARKKFHQLSLAIK 125
Query: 607 YCHERGVVHRDIKCENLLMDHGLNIKLSDFGFAR 708
YCH+ VVHRD+KC+NLL+D NIKLSDF F++
Sbjct: 126 YCHDLDVVHRDLKCDNLLLDKDFNIKLSDFSFSK 159
>AY461663-1|AAS17971.1| 328|Homo sapiens testis-specific serine
kinase 4 protein.
Length = 328
Score = 158 bits (384), Expect = 2e-38
Identities = 73/154 (47%), Positives = 106/154 (68%)
Frame = +1
Query: 247 TVLESHGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVV 426
++++ +GY +G+ IG GSY +V A + VA+KIISK +A DYL KFLPREI+V+
Sbjct: 18 SLMDEYGYEVGKAIGHGSYGSVYEAFYTKQKVMVAVKIISKKKASDDYLNKFLPREIQVM 77
Query: 427 KGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVD 606
K L+H+ LI F +AIE+T RVYI++E A+ G +L+ I++ E +WF QL +
Sbjct: 78 KVLRHKYLINFYRAIESTSRVYIILELAQGGDVLEWIQRYGACSEPLAGKWFSQLTLGIA 137
Query: 607 YCHERGVVHRDIKCENLLMDHGLNIKLSDFGFAR 708
Y H + +VHRD+K ENLL+D N+K+SDFGFA+
Sbjct: 138 YLHSKSIVHRDLKLENLLLDKWENVKISDFGFAK 171
>BC035354-1|AAH35354.1| 268|Homo sapiens testis-specific serine
kinase 3 protein.
Length = 268
Score = 156 bits (378), Expect = 9e-38
Identities = 70/153 (45%), Positives = 108/153 (70%), Gaps = 1/153 (0%)
Frame = +1
Query: 253 LESHGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKG 432
L S+GY LG+TIG G+Y+ VK A S +H +VAIK+I K P +++++FLPRE+++V+
Sbjct: 5 LLSNGYQLGKTIGEGTYSKVKEAFSKKHQRKVAIKVIDKMGGPEEFIQRFLPRELQIVRT 64
Query: 433 LKHENLIRFLQAIETTH-RVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDY 609
L H+N+I+ + +E+ ++ +VME AE G + D + + E+R + F+Q+VEA+ Y
Sbjct: 65 LDHKNIIQVYEMLESADGKICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVEAIRY 124
Query: 610 CHERGVVHRDIKCENLLMDHGLNIKLSDFGFAR 708
CH GV HRD+KCEN L+ G N+KL+DFGFA+
Sbjct: 125 CHGCGVAHRDLKCENALL-QGFNLKLTDFGFAK 156
>AY048701-1|AAL02128.1| 268|Homo sapiens TSSK3 protein.
Length = 268
Score = 156 bits (378), Expect = 9e-38
Identities = 70/153 (45%), Positives = 108/153 (70%), Gaps = 1/153 (0%)
Frame = +1
Query: 253 LESHGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKG 432
L S+GY LG+TIG G+Y+ VK A S +H +VAIK+I K P +++++FLPRE+++V+
Sbjct: 5 LLSNGYQLGKTIGEGTYSKVKEAFSKKHQRKVAIKVIDKMGGPEEFIQRFLPRELQIVRT 64
Query: 433 LKHENLIRFLQAIETTH-RVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDY 609
L H+N+I+ + +E+ ++ +VME AE G + D + + E+R + F+Q+VEA+ Y
Sbjct: 65 LDHKNIIQVYEMLESADGKICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVEAIRY 124
Query: 610 CHERGVVHRDIKCENLLMDHGLNIKLSDFGFAR 708
CH GV HRD+KCEN L+ G N+KL+DFGFA+
Sbjct: 125 CHGCGVAHRDLKCENALL-QGFNLKLTDFGFAK 156
>AL109945-4|CAI22888.1| 268|Homo sapiens testis-specific serine
kinase 3 protein.
Length = 268
Score = 156 bits (378), Expect = 9e-38
Identities = 70/153 (45%), Positives = 108/153 (70%), Gaps = 1/153 (0%)
Frame = +1
Query: 253 LESHGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKG 432
L S+GY LG+TIG G+Y+ VK A S +H +VAIK+I K P +++++FLPRE+++V+
Sbjct: 5 LLSNGYQLGKTIGEGTYSKVKEAFSKKHQRKVAIKVIDKMGGPEEFIQRFLPRELQIVRT 64
Query: 433 LKHENLIRFLQAIETTH-RVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDY 609
L H+N+I+ + +E+ ++ +VME AE G + D + + E+R + F+Q+VEA+ Y
Sbjct: 65 LDHKNIIQVYEMLESADGKICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVEAIRY 124
Query: 610 CHERGVVHRDIKCENLLMDHGLNIKLSDFGFAR 708
CH GV HRD+KCEN L+ G N+KL+DFGFA+
Sbjct: 125 CHGCGVAHRDLKCENALL-QGFNLKLTDFGFAK 156
>AF296450-1|AAK97141.1| 268|Homo sapiens testis-specific
serine/threonine kinase 3 protein.
Length = 268
Score = 156 bits (378), Expect = 9e-38
Identities = 70/153 (45%), Positives = 108/153 (70%), Gaps = 1/153 (0%)
Frame = +1
Query: 253 LESHGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKG 432
L S+GY LG+TIG G+Y+ VK A S +H +VAIK+I K P +++++FLPRE+++V+
Sbjct: 5 LLSNGYQLGKTIGEGTYSKVKEAFSKKHQRKVAIKVIDKMGGPEEFIQRFLPRELQIVRT 64
Query: 433 LKHENLIRFLQAIETTH-RVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDY 609
L H+N+I+ + +E+ ++ +VME AE G + D + + E+R + F+Q+VEA+ Y
Sbjct: 65 LDHKNIIQVYEMLESADGKICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVEAIRY 124
Query: 610 CHERGVVHRDIKCENLLMDHGLNIKLSDFGFAR 708
CH GV HRD+KCEN L+ G N+KL+DFGFA+
Sbjct: 125 CHGCGVAHRDLKCENALL-QGFNLKLTDFGFAK 156
>CR456587-1|CAG30473.1| 358|Homo sapiens STK22A protein.
Length = 358
Score = 154 bits (373), Expect = 3e-37
Identities = 71/155 (45%), Positives = 105/155 (67%), Gaps = 1/155 (0%)
Frame = +1
Query: 247 TVLESHGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVV 426
TVL GY++G +G GSYA VK A S+R VA+KII + + P D++++FLPRE++++
Sbjct: 5 TVLRKKGYIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPREMDIL 64
Query: 427 KGLKHENLIRFLQAIETTH-RVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAV 603
+ H ++I+ + ET+ R+YI+ME G LL+ I+ + E R+ F+QL AV
Sbjct: 65 ATVNHGSIIKTYEIFETSDGRIYIIMELGVQGDLLEFIKCQGALHEDVARKMFRQLSSAV 124
Query: 604 DYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFAR 708
YCH+ +VHRD+KCENLL+D NIKLSDFGF++
Sbjct: 125 KYCHDLDIVHRDLKCENLLLDKDFNIKLSDFGFSK 159
>BC037781-1|AAH37781.1| 358|Homo sapiens testis-specific serine
kinase 2 protein.
Length = 358
Score = 154 bits (373), Expect = 3e-37
Identities = 71/155 (45%), Positives = 105/155 (67%), Gaps = 1/155 (0%)
Frame = +1
Query: 247 TVLESHGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVV 426
TVL GY++G +G GSYA VK A S+R VA+KII + + P D++++FLPRE++++
Sbjct: 5 TVLRKKGYIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPREMDIL 64
Query: 427 KGLKHENLIRFLQAIETTH-RVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAV 603
+ H ++I+ + ET+ R+YI+ME G LL+ I+ + E R+ F+QL AV
Sbjct: 65 ATVNHGSIIKTYEIFETSDGRIYIIMELGVQGDLLEFIKCQGALHEDVARKMFRQLSSAV 124
Query: 604 DYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFAR 708
YCH+ +VHRD+KCENLL+D NIKLSDFGF++
Sbjct: 125 KYCHDLDIVHRDLKCENLLLDKDFNIKLSDFGFSK 159
>AF362953-1|AAK98531.1| 358|Homo sapiens testis specific
serine/threonine kinase 2 protein.
Length = 358
Score = 154 bits (373), Expect = 3e-37
Identities = 71/155 (45%), Positives = 105/155 (67%), Gaps = 1/155 (0%)
Frame = +1
Query: 247 TVLESHGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVV 426
TVL GY++G +G GSYA VK A S+R VA+KII + + P D++++FLPRE++++
Sbjct: 5 TVLRKKGYIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPREMDIL 64
Query: 427 KGLKHENLIRFLQAIETTH-RVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAV 603
+ H ++I+ + ET+ R+YI+ME G LL+ I+ + E R+ F+QL AV
Sbjct: 65 ATVNHGSIIKTYEIFETSDGRIYIIMELGVQGDLLEFIKCQGALHEDVARKMFRQLSSAV 124
Query: 604 DYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFAR 708
YCH+ +VHRD+KCENLL+D NIKLSDFGF++
Sbjct: 125 KYCHDLDIVHRDLKCENLLLDKDFNIKLSDFGFSK 159
>AB284523-1|BAF41974.1| 358|Homo sapiens testis-specific serine
kinase 2 protein.
Length = 358
Score = 154 bits (373), Expect = 3e-37
Identities = 71/155 (45%), Positives = 105/155 (67%), Gaps = 1/155 (0%)
Frame = +1
Query: 247 TVLESHGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVV 426
TVL GY++G +G GSYA VK A S+R VA+KII + + P D++++FLPRE++++
Sbjct: 5 TVLRKKGYIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPREMDIL 64
Query: 427 KGLKHENLIRFLQAIETTH-RVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAV 603
+ H ++I+ + ET+ R+YI+ME G LL+ I+ + E R+ F+QL AV
Sbjct: 65 ATVNHGSIIKTYEIFETSDGRIYIIMELGVQGDLLEFIKCQGALHEDVARKMFRQLSSAV 124
Query: 604 DYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFAR 708
YCH+ +VHRD+KCENLL+D NIKLSDFGF++
Sbjct: 125 KYCHDLDIVHRDLKCENLLLDKDFNIKLSDFGFSK 159
>AK131042-1|BAC85482.1| 338|Homo sapiens protein ( Homo sapiens
cDNA FLJ29008 fis, clone TST06032. ).
Length = 338
Score = 148 bits (359), Expect = 2e-35
Identities = 74/164 (45%), Positives = 106/164 (64%), Gaps = 10/164 (6%)
Frame = +1
Query: 247 TVLESHGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVV 426
++++ +GY +G+ IG GSY +V A + VA+KIISK +A DYL KFLPREI+V+
Sbjct: 18 SLMDEYGYEVGKAIGHGSYGSVYEAFYTKQKVMVAVKIISKKKASDDYLNKFLPREIQVM 77
Query: 427 KGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVD 606
K L+H+ LI F +AIE+T RVYI++E A+ G +L+ IR+ E +WF QL +
Sbjct: 78 KVLRHKYLINFYRAIESTSRVYIILELAQGGDVLEWIRRYGACSEPLAGKWFSQLTLGIA 137
Query: 607 YCHERGVVH----------RDIKCENLLMDHGLNIKLSDFGFAR 708
Y H + +VH RD+K ENLL+D N+K+SDFGFA+
Sbjct: 138 YLHSKSIVHRLMPSLSAAGRDLKLENLLLDKWENVKISDFGFAK 181
>AY120867-1|AAM55491.1| 752|Homo sapiens MAP/microtubule
affinity-regulating kinase-like 1 protein.
Length = 752
Score = 137 bits (331), Expect = 4e-32
Identities = 66/146 (45%), Positives = 93/146 (63%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y L RTIG G++A VK+A +VAIKII K Q L+K RE+ ++KGL H N
Sbjct: 59 YRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPSSLQKLF-REVRIMKGLNHPN 117
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+++ + IET +Y+VMEYA G + D + + E R F+Q+V AV YCH++ +
Sbjct: 118 IVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNI 177
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFA 705
VHRD+K ENLL+D NIK++DFGF+
Sbjct: 178 VHRDLKAENLLLDAEANIKIADFGFS 203
>AY057448-1|AAL23683.1| 752|Homo sapiens MARK4 serine/threonine
protein kinase protein.
Length = 752
Score = 137 bits (331), Expect = 4e-32
Identities = 66/146 (45%), Positives = 93/146 (63%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y L RTIG G++A VK+A +VAIKII K Q L+K RE+ ++KGL H N
Sbjct: 59 YRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPSSLQKLF-REVRIMKGLNHPN 117
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+++ + IET +Y+VMEYA G + D + + E R F+Q+V AV YCH++ +
Sbjct: 118 IVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNI 177
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFA 705
VHRD+K ENLL+D NIK++DFGF+
Sbjct: 178 VHRDLKAENLLLDAEANIKIADFGFS 203
>AK075272-1|BAC11510.1| 752|Homo sapiens protein ( Homo sapiens
cDNA FLJ90791 fis, clone THYRO1001593, moderately
similar to PUTATIVE SERINE/THREONINE-PROTEIN KINASE P78
(EC 2.7.1.-). ).
Length = 752
Score = 137 bits (331), Expect = 4e-32
Identities = 66/146 (45%), Positives = 93/146 (63%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y L RTIG G++A VK+A +VAIKII K Q L+K RE+ ++KGL H N
Sbjct: 59 YRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPSSLQKLF-REVRIMKGLNHPN 117
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+++ + IET +Y+VMEYA G + D + + E R F+Q+V AV YCH++ +
Sbjct: 118 IVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNI 177
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFA 705
VHRD+K ENLL+D NIK++DFGF+
Sbjct: 178 VHRDLKAENLLLDAEANIKIADFGFS 203
>AB058763-1|BAB47489.1| 689|Homo sapiens KIAA1860 protein protein.
Length = 689
Score = 137 bits (331), Expect = 4e-32
Identities = 66/146 (45%), Positives = 93/146 (63%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y L RTIG G++A VK+A +VAIKII K Q L+K RE+ ++KGL H N
Sbjct: 60 YRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPSSLQKLF-REVRIMKGLNHPN 118
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+++ + IET +Y+VMEYA G + D + + E R F+Q+V AV YCH++ +
Sbjct: 119 IVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNI 178
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFA 705
VHRD+K ENLL+D NIK++DFGF+
Sbjct: 179 VHRDLKAENLLLDAEANIKIADFGFS 204
>BC014611-1|AAH14611.1| 273|Homo sapiens testis-specific serine
kinase 6 protein.
Length = 273
Score = 136 bits (330), Expect = 6e-32
Identities = 66/155 (42%), Positives = 103/155 (66%), Gaps = 2/155 (1%)
Frame = +1
Query: 250 VLESHGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVK 429
+L GY LGRTIG GSY+ VKVA+S ++ VAIK++ + +AP D++ KFLPRE+ +++
Sbjct: 6 LLSELGYKLGRTIGEGSYSKVKVATSKKYKGTVAIKVVDRRRAPPDFVNKFLPRELSILR 65
Query: 430 GLKHENLIRFLQAIETTH-RVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVD 606
G++H +++ + IE + ++YIVME A LL ++++ I + R F Q+ AV
Sbjct: 66 GVRHPHIVHVFEFIEVCNGKLYIVMEAAAT-DLLQAVQRNGRIPGVQARDLFAQIAGAVR 124
Query: 607 YCHERGVVHRDIKCENLLMD-HGLNIKLSDFGFAR 708
Y H+ +VHRD+KCEN+L+ +KL+DFGF R
Sbjct: 125 YLHDHHLVHRDLKCENVLLSPDERRVKLTDFGFGR 159
>AK172841-1|BAD18805.1| 406|Homo sapiens protein ( Homo sapiens
cDNA FLJ24002 fis, clone KAIA4350, highly similar to
Homo sapiens serine/threonine protein kinase SSTK
(SSTK). ).
Length = 406
Score = 136 bits (330), Expect = 6e-32
Identities = 66/155 (42%), Positives = 103/155 (66%), Gaps = 2/155 (1%)
Frame = +1
Query: 250 VLESHGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVK 429
+L GY LGRTIG GSY+ VKVA+S ++ VAIK++ + +AP D++ KFLPRE+ +++
Sbjct: 6 LLSELGYKLGRTIGEGSYSKVKVATSKKYKGTVAIKVVDRRRAPPDFVNKFLPRELSILR 65
Query: 430 GLKHENLIRFLQAIETTH-RVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVD 606
G++H +++ + IE + ++YIVME A LL ++++ I + R F Q+ AV
Sbjct: 66 GVRHPHIVHVFEFIEVCNGKLYIVMEAAAT-DLLQAVQRNGRIPGVQARDLFAQIAGAVR 124
Query: 607 YCHERGVVHRDIKCENLLMD-HGLNIKLSDFGFAR 708
Y H+ +VHRD+KCEN+L+ +KL+DFGF R
Sbjct: 125 YLHDHHLVHRDLKCENVLLSPDERRVKLTDFGFGR 159
>AF329483-1|AAK48827.1| 273|Homo sapiens serine/threonine protein
kinase SSTK protein.
Length = 273
Score = 136 bits (330), Expect = 6e-32
Identities = 66/155 (42%), Positives = 103/155 (66%), Gaps = 2/155 (1%)
Frame = +1
Query: 250 VLESHGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVK 429
+L GY LGRTIG GSY+ VKVA+S ++ VAIK++ + +AP D++ KFLPRE+ +++
Sbjct: 6 LLSELGYKLGRTIGEGSYSKVKVATSKKYKGTVAIKVVDRRRAPPDFVNKFLPRELSILR 65
Query: 430 GLKHENLIRFLQAIETTH-RVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVD 606
G++H +++ + IE + ++YIVME A LL ++++ I + R F Q+ AV
Sbjct: 66 GVRHPHIVHVFEFIEVCNGKLYIVMEAAAT-DLLQAVQRNGRIPGVQARDLFAQIAGAVR 124
Query: 607 YCHERGVVHRDIKCENLLMD-HGLNIKLSDFGFAR 708
Y H+ +VHRD+KCEN+L+ +KL+DFGF R
Sbjct: 125 YLHDHHLVHRDLKCENVLLSPDERRVKLTDFGFGR 159
>BC128510-1|AAI28511.1| 1203|Homo sapiens KIAA0999 protein protein.
Length = 1203
Score = 135 bits (327), Expect = 1e-31
Identities = 68/146 (46%), Positives = 94/146 (64%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y + RTIG G++A VK A+ +VAIKII K Q + LKK RE++++K L H +
Sbjct: 8 YEIDRTIGKGNFAVVKRATHLVTKAKVAIKIIDKTQLDEENLKKIF-REVQIMKMLCHPH 66
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+IR Q +ET +Y+V EYA G + D + + E RR FKQ+V AV +CH R +
Sbjct: 67 IIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVTAVYFCHCRNI 126
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFA 705
VHRD+K ENLL+D LNIK++DFGF+
Sbjct: 127 VHRDLKAENLLLDANLNIKIADFGFS 152
>BC038504-1|AAH38504.1| 783|Homo sapiens SNF1-like kinase protein.
Length = 783
Score = 135 bits (327), Expect = 1e-31
Identities = 63/145 (43%), Positives = 96/145 (66%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y + RT+G G++A VK+A QVAIKII K + L+K RE++++K L H +
Sbjct: 27 YDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDSSNLEKIY-REVQLMKLLNHPH 85
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+I+ Q +ET +YIV E+A+NG + D + + H+ E R+ F Q++ AV+YCH+ +
Sbjct: 86 IIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSAVEYCHDHHI 145
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGF 702
VHRD+K ENLL+D ++IKL+DFGF
Sbjct: 146 VHRDLKTENLLLDGNMDIKLADFGF 170
>AK131076-1|BAC85126.1| 764|Homo sapiens FLJ00263 protein protein.
Length = 764
Score = 135 bits (327), Expect = 1e-31
Identities = 63/145 (43%), Positives = 96/145 (66%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y + RT+G G++A VK+A QVAIKII K + L+K RE++++K L H +
Sbjct: 8 YDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDSSNLEKIY-REVQLMKLLNHPH 66
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+I+ Q +ET +YIV E+A+NG + D + + H+ E R+ F Q++ AV+YCH+ +
Sbjct: 67 IIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSAVEYCHDHHI 126
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGF 702
VHRD+K ENLL+D ++IKL+DFGF
Sbjct: 127 VHRDLKTENLLLDGNMDIKLADFGF 151
>AB047786-1|BAD74070.1| 783|Homo sapiens serine/threonine protein
kinase protein.
Length = 783
Score = 135 bits (327), Expect = 1e-31
Identities = 63/145 (43%), Positives = 96/145 (66%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y + RT+G G++A VK+A QVAIKII K + L+K RE++++K L H +
Sbjct: 27 YDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDSSNLEKIY-REVQLMKLLNHPH 85
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+I+ Q +ET +YIV E+A+NG + D + + H+ E R+ F Q++ AV+YCH+ +
Sbjct: 86 IIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSAVEYCHDHHI 145
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGF 702
VHRD+K ENLL+D ++IKL+DFGF
Sbjct: 146 VHRDLKTENLLLDGNMDIKLADFGF 170
>AB023216-1|BAA76843.2| 1371|Homo sapiens KIAA0999 protein protein.
Length = 1371
Score = 135 bits (327), Expect = 1e-31
Identities = 68/146 (46%), Positives = 94/146 (64%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y + RTIG G++A VK A+ +VAIKII K Q + LKK RE++++K L H +
Sbjct: 116 YEIDRTIGKGNFAVVKRATHLVTKAKVAIKIIDKTQLDEENLKKIF-REVQIMKMLCHPH 174
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+IR Q +ET +Y+V EYA G + D + + E RR FKQ+V AV +CH R +
Sbjct: 175 IIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVTAVYFCHCRNI 234
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFA 705
VHRD+K ENLL+D LNIK++DFGF+
Sbjct: 235 VHRDLKAENLLLDANLNIKIADFGFS 260
>BC084540-1|AAH84540.1| 724|Homo sapiens MAP/microtubule
affinity-regulating kinase 2 protein.
Length = 724
Score = 135 bits (326), Expect = 2e-31
Identities = 68/184 (36%), Positives = 107/184 (58%), Gaps = 2/184 (1%)
Frame = +1
Query: 160 THDNVLGEMSAEPTATVHSGVEAKTERKLTVLESH--GYMLGRTIGSGSYATVKVASSDR 333
T LG + ++P++ + + + + H Y L +TIG G++A VK+A
Sbjct: 16 TEQPTLGHLDSKPSSKSNM-IRGRNSATSADEQPHIGNYRLLKTIGKGNFAKVKLARHIL 74
Query: 334 HNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAE 513
+VA+KII K Q L+K RE+ ++K L H N+++ + IET +Y+VMEYA
Sbjct: 75 TGKEVAVKIIDKTQLNSSSLQKLF-REVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYAS 133
Query: 514 NGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSD 693
G + D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+D +NIK++D
Sbjct: 134 GGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIAD 193
Query: 694 FGFA 705
FGF+
Sbjct: 194 FGFS 197
>BC008771-1|AAH08771.2| 778|Homo sapiens MARK2 protein protein.
Length = 778
Score = 135 bits (326), Expect = 2e-31
Identities = 68/184 (36%), Positives = 107/184 (58%), Gaps = 2/184 (1%)
Frame = +1
Query: 160 THDNVLGEMSAEPTATVHSGVEAKTERKLTVLESH--GYMLGRTIGSGSYATVKVASSDR 333
T LG + ++P++ + + + + H Y L +TIG G++A VK+A
Sbjct: 6 TEQPTLGHLDSKPSSKSNM-IRGRNSATSADEQPHIGNYRLLKTIGKGNFAKVKLARHIL 64
Query: 334 HNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAE 513
+VA+KII K Q L+K RE+ ++K L H N+++ + IET +Y+VMEYA
Sbjct: 65 TGKEVAVKIIDKTQLNSSSLQKLF-REVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYAS 123
Query: 514 NGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSD 693
G + D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+D +NIK++D
Sbjct: 124 GGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIAD 183
Query: 694 FGFA 705
FGF+
Sbjct: 184 FGFS 187
>AB188493-1|BAD37141.1| 719|Homo sapiens serine/threonine kinase
protein.
Length = 719
Score = 135 bits (326), Expect = 2e-31
Identities = 68/184 (36%), Positives = 107/184 (58%), Gaps = 2/184 (1%)
Frame = +1
Query: 160 THDNVLGEMSAEPTATVHSGVEAKTERKLTVLESH--GYMLGRTIGSGSYATVKVASSDR 333
T LG + ++P++ + + + + H Y L +TIG G++A VK+A
Sbjct: 16 TEQPTLGHLDSKPSSKSNM-IRGRNSATSADEQPHIGNYRLLKTIGKGNFAKVKLARHIL 74
Query: 334 HNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAE 513
+VA+KII K Q L+K RE+ ++K L H N+++ + IET +Y+VMEYA
Sbjct: 75 TGKEVAVKIIDKTQLNSSSLQKLF-REVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYAS 133
Query: 514 NGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSD 693
G + D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+D +NIK++D
Sbjct: 134 GGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIAD 193
Query: 694 FGFA 705
FGF+
Sbjct: 194 FGFS 197
>AB088047-1|BAC03375.1| 752|Homo sapiens microtubule
affinity-regulating kinase-like1 protein.
Length = 752
Score = 135 bits (326), Expect = 2e-31
Identities = 66/146 (45%), Positives = 92/146 (63%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y L RTIG G+ A VK+A +VAIKII K Q L+K RE+ ++KGL H N
Sbjct: 59 YRLLRTIGKGNSAKVKLARHILTGREVAIKIIDKTQLNPSSLQKLF-REVRIMKGLNHPN 117
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+++ + IET +Y+VMEYA G + D + + E R F+Q+V AV YCH++ +
Sbjct: 118 IVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNI 177
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFA 705
VHRD+K ENLL+D NIK++DFGF+
Sbjct: 178 VHRDLKAENLLLDAEANIKIADFGFS 203
>AB049127-1|BAB39380.1| 688|Homo sapiens MAP/microtubule
affinity-regulating kinase like 1 protein.
Length = 688
Score = 135 bits (326), Expect = 2e-31
Identities = 66/146 (45%), Positives = 92/146 (63%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y L RTIG G+ A VK+A +VAIKII K Q L+K RE+ ++KGL H N
Sbjct: 59 YRLLRTIGKGNSAKVKLARHILTGREVAIKIIDKTQLNPSSLQKLF-REVRIMKGLNHPN 117
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+++ + IET +Y+VMEYA G + D + + E R F+Q+V AV YCH++ +
Sbjct: 118 IVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNI 177
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFA 705
VHRD+K ENLL+D NIK++DFGF+
Sbjct: 178 VHRDLKAENLLLDAEANIKIADFGFS 203
>BC117183-1|AAI17184.1| 926|Homo sapiens SNF1-like kinase 2
protein.
Length = 926
Score = 134 bits (325), Expect = 2e-31
Identities = 63/145 (43%), Positives = 95/145 (65%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y + T+G G++A VK+ +VAIKII K Q L+K RE++++K L H +
Sbjct: 20 YDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVNLEKIY-REVQIMKMLDHPH 78
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+I+ Q +ET +Y+V EYA+NG + D + ++E+ RR F Q++ AVDYCH R +
Sbjct: 79 IIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKI 138
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGF 702
VHRD+K ENLL+D+ +NIK++DFGF
Sbjct: 139 VHRDLKAENLLLDNNMNIKIADFGF 163
>BC113459-1|AAI13460.1| 926|Homo sapiens SNF1-like kinase 2
protein.
Length = 926
Score = 134 bits (325), Expect = 2e-31
Identities = 63/145 (43%), Positives = 95/145 (65%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y + T+G G++A VK+ +VAIKII K Q L+K RE++++K L H +
Sbjct: 20 YDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVNLEKIY-REVQIMKMLDHPH 78
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+I+ Q +ET +Y+V EYA+NG + D + ++E+ RR F Q++ AVDYCH R +
Sbjct: 79 IIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKI 138
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGF 702
VHRD+K ENLL+D+ +NIK++DFGF
Sbjct: 139 VHRDLKAENLLLDNNMNIKIADFGF 163
>AB084424-1|BAB91442.1| 346|Homo sapiens KIAA0781 protein protein.
Length = 346
Score = 134 bits (325), Expect = 2e-31
Identities = 63/145 (43%), Positives = 95/145 (65%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y + T+G G++A VK+ +VAIKII K Q L+K RE++++K L H +
Sbjct: 18 YDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVNLEKIY-REVQIMKMLDHPH 76
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+I+ Q +ET +Y+V EYA+NG + D + ++E+ RR F Q++ AVDYCH R +
Sbjct: 77 IIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKI 136
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGF 702
VHRD+K ENLL+D+ +NIK++DFGF
Sbjct: 137 VHRDLKAENLLLDNNMNIKIADFGF 161
>AB018324-1|BAA34501.3| 950|Homo sapiens KIAA0781 protein protein.
Length = 950
Score = 134 bits (325), Expect = 2e-31
Identities = 63/145 (43%), Positives = 95/145 (65%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y + T+G G++A VK+ +VAIKII K Q L+K RE++++K L H +
Sbjct: 44 YDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVNLEKIY-REVQIMKMLDHPH 102
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+I+ Q +ET +Y+V EYA+NG + D + ++E+ RR F Q++ AVDYCH R +
Sbjct: 103 IIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKI 162
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGF 702
VHRD+K ENLL+D+ +NIK++DFGF
Sbjct: 163 VHRDLKAENLLLDNNMNIKIADFGF 187
>X97630-1|CAA66229.1| 745|Homo sapiens serine/threonine protein
kinase protein.
Length = 745
Score = 134 bits (323), Expect = 4e-31
Identities = 63/146 (43%), Positives = 93/146 (63%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y L +TIG G++A VK+A +VA+KII K Q L+K RE+ ++K L H N
Sbjct: 20 YRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLF-REVRIMKVLNHPN 78
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+++ + IET +Y+VMEYA G + D + + E R F+Q+V AV YCH++ +
Sbjct: 79 IVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFI 138
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFA 705
VHRD+K ENLL+D +NIK++DFGF+
Sbjct: 139 VHRDLKAENLLLDADMNIKIADFGFS 164
>BT007342-1|AAP36006.1| 755|Homo sapiens MAP/microtubule
affinity-regulating kinase 2 protein.
Length = 755
Score = 134 bits (323), Expect = 4e-31
Identities = 63/146 (43%), Positives = 93/146 (63%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y L +TIG G++A VK+A +VA+KII K Q L+K RE+ ++K L H N
Sbjct: 20 YRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLF-REVRIMKVLNHPN 78
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+++ + IET +Y+VMEYA G + D + + E R F+Q+V AV YCH++ +
Sbjct: 79 IVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFI 138
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFA 705
VHRD+K ENLL+D +NIK++DFGF+
Sbjct: 139 VHRDLKAENLLLDADMNIKIADFGFS 164
>AF387638-1|AAK82368.1| 691|Homo sapiens Ser/Thr protein kinase
PAR-1Balpha protein.
Length = 691
Score = 134 bits (323), Expect = 4e-31
Identities = 63/146 (43%), Positives = 93/146 (63%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y L +TIG G++A VK+A +VA+KII K Q L+K RE+ ++K L H N
Sbjct: 20 YRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLF-REVRIMKVLNHPN 78
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+++ + IET +Y+VMEYA G + D + + E R F+Q+V AV YCH++ +
Sbjct: 79 IVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFI 138
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFA 705
VHRD+K ENLL+D +NIK++DFGF+
Sbjct: 139 VHRDLKAENLLLDADMNIKIADFGFS 164
>BC114478-1|AAI14479.1| 795|Homo sapiens MARK1 protein protein.
Length = 795
Score = 133 bits (321), Expect = 7e-31
Identities = 63/146 (43%), Positives = 93/146 (63%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y L +TIG G++A VK+A +VA+KII K Q L+K RE+ ++K L H N
Sbjct: 60 YRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLF-REVRIMKILNHPN 118
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+++ + IET +Y+VMEYA G + D + + E R F+Q+V AV YCH++ +
Sbjct: 119 IVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYI 178
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFA 705
VHRD+K ENLL+D +NIK++DFGF+
Sbjct: 179 VHRDLKAENLLLDGDMNIKIADFGFS 204
>BC113869-1|AAI13870.1| 795|Homo sapiens MARK1 protein protein.
Length = 795
Score = 133 bits (321), Expect = 7e-31
Identities = 63/146 (43%), Positives = 93/146 (63%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y L +TIG G++A VK+A +VA+KII K Q L+K RE+ ++K L H N
Sbjct: 60 YRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLF-REVRIMKILNHPN 118
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+++ + IET +Y+VMEYA G + D + + E R F+Q+V AV YCH++ +
Sbjct: 119 IVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYI 178
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFA 705
VHRD+K ENLL+D +NIK++DFGF+
Sbjct: 179 VHRDLKAENLLLDGDMNIKIADFGFS 204
>AL592406-3|CAH72463.1| 795|Homo sapiens MAP/microtubule
affinity-regulating kinase 1 protein.
Length = 795
Score = 133 bits (321), Expect = 7e-31
Identities = 63/146 (43%), Positives = 93/146 (63%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y L +TIG G++A VK+A +VA+KII K Q L+K RE+ ++K L H N
Sbjct: 60 YRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLF-REVRIMKILNHPN 118
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+++ + IET +Y+VMEYA G + D + + E R F+Q+V AV YCH++ +
Sbjct: 119 IVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYI 178
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFA 705
VHRD+K ENLL+D +NIK++DFGF+
Sbjct: 179 VHRDLKAENLLLDGDMNIKIADFGFS 204
>AF154845-1|AAF72103.1| 795|Homo sapiens MARK protein.
Length = 795
Score = 133 bits (321), Expect = 7e-31
Identities = 63/146 (43%), Positives = 93/146 (63%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y L +TIG G++A VK+A +VA+KII K Q L+K RE+ ++K L H N
Sbjct: 60 YRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLF-REVRIMKILNHPN 118
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+++ + IET +Y+VMEYA G + D + + E R F+Q+V AV YCH++ +
Sbjct: 119 IVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYI 178
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFA 705
VHRD+K ENLL+D +NIK++DFGF+
Sbjct: 179 VHRDLKAENLLLDGDMNIKIADFGFS 204
>U64205-1|AAC15093.1| 729|Homo sapiens Cdc25C associated protein
kinase C-TAK1 protein.
Length = 729
Score = 132 bits (320), Expect = 9e-31
Identities = 63/146 (43%), Positives = 93/146 (63%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y L +TIG G++A VK+A +VAIKII K Q L+K RE+ ++K L H N
Sbjct: 56 YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLF-REVRIMKILNHPN 114
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+++ + IET +Y++MEYA G + D + + E R F+Q+V AV YCH++ +
Sbjct: 115 IVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRI 174
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFA 705
VHRD+K ENLL+D +NIK++DFGF+
Sbjct: 175 VHRDLKAENLLLDADMNIKIADFGFS 200
>M80359-1|AAA59991.1| 713|Homo sapiens protein p78 protein.
Length = 713
Score = 132 bits (320), Expect = 9e-31
Identities = 63/146 (43%), Positives = 93/146 (63%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y L +TIG G++A VK+A +VAIKII K Q L+K RE+ ++K L H N
Sbjct: 56 YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLF-REVRIMKILNHPN 114
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+++ + IET +Y++MEYA G + D + + E R F+Q+V AV YCH++ +
Sbjct: 115 IVKLFEVIETQKTLYLIMEYASGGKVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRI 174
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFA 705
VHRD+K ENLL+D +NIK++DFGF+
Sbjct: 175 VHRDLKAENLLLDADMNIKIADFGFS 200
>BC024773-1|AAH24773.1| 729|Homo sapiens MAP/microtubule
affinity-regulating kinase 3 protein.
Length = 729
Score = 132 bits (320), Expect = 9e-31
Identities = 63/146 (43%), Positives = 93/146 (63%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y L +TIG G++A VK+A +VAIKII K Q L+K RE+ ++K L H N
Sbjct: 56 YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLF-REVRIMKILNHPN 114
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+++ + IET +Y++MEYA G + D + + E R F+Q+V AV YCH++ +
Sbjct: 115 IVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRI 174
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFA 705
VHRD+K ENLL+D +NIK++DFGF+
Sbjct: 175 VHRDLKAENLLLDADMNIKIADFGFS 200
>AF465413-1|AAL69982.1| 753|Homo sapiens MAP/microtubule
affinity-regulating kinase 3 long isoform protein.
Length = 753
Score = 132 bits (320), Expect = 9e-31
Identities = 63/146 (43%), Positives = 93/146 (63%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y L +TIG G++A VK+A +VAIKII K Q L+K RE+ ++K L H N
Sbjct: 56 YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLF-REVRIMKILNHPN 114
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+++ + IET +Y++MEYA G + D + + E R F+Q+V AV YCH++ +
Sbjct: 115 IVKLFEVIETEKTLYLIMEYASGGKVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRI 174
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFA 705
VHRD+K ENLL+D +NIK++DFGF+
Sbjct: 175 VHRDLKAENLLLDADMNIKIADFGFS 200
>AF387637-1|AAK82367.1| 744|Homo sapiens Ser/Thr protein kinase
PAR-1A protein.
Length = 744
Score = 132 bits (320), Expect = 9e-31
Identities = 63/146 (43%), Positives = 93/146 (63%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y L +TIG G++A VK+A +VAIKII K Q L+K RE+ ++K L H N
Sbjct: 56 YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLF-REVRIMKILNHPN 114
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+++ + IET +Y++MEYA G + D + + E R F+Q+V AV YCH++ +
Sbjct: 115 IVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRI 174
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFA 705
VHRD+K ENLL+D +NIK++DFGF+
Sbjct: 175 VHRDLKAENLLLDADMNIKIADFGFS 200
>AP001751-1|BAA95536.1| 786|Homo sapiens SNF1LK protein.
Length = 786
Score = 129 bits (312), Expect = 9e-30
Identities = 63/148 (42%), Positives = 96/148 (64%), Gaps = 3/148 (2%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y + RT+G G++A VK+A QVAIKII K + L+K RE++++K L H +
Sbjct: 27 YDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDSSNLEKIY-REVQLMKLLNHPH 85
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+I+ Q +ET +YIV E+A+NG + D + + H+ E R+ F Q++ AV+YCH+ +
Sbjct: 86 IIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSAVEYCHDHHI 145
Query: 628 VHRDIKCENLLMDHGLNIKLS---DFGF 702
VHRD+K ENLL+D ++IKL+ DFGF
Sbjct: 146 VHRDLKTENLLLDGNMDIKLAGTEDFGF 173
>AB011109-1|BAA25463.2| 698|Homo sapiens KIAA0537 protein protein.
Length = 698
Score = 126 bits (303), Expect = 1e-28
Identities = 60/148 (40%), Positives = 87/148 (58%)
Frame = +1
Query: 262 HGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKH 441
H Y L T+G G+Y VK A+ VAIK I K + + + REIE++ L H
Sbjct: 90 HRYELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDEQDMVHIRREIEIMSSLNH 149
Query: 442 ENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHER 621
++I + E ++ I+MEYA G L D I + + + E R +F+Q+V AV YCH+
Sbjct: 150 PHIISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCHKN 209
Query: 622 GVVHRDIKCENLLMDHGLNIKLSDFGFA 705
GVVHRD+K EN+L+D NIK++DFG +
Sbjct: 210 GVVHRDLKLENILLDDNCNIKIADFGLS 237
>BC121188-1|AAI21189.1| 185|Homo sapiens KIAA0999 protein protein.
Length = 185
Score = 125 bits (302), Expect = 1e-28
Identities = 64/141 (45%), Positives = 89/141 (63%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y + RTIG G++A VK A+ +VAIKII K Q + LKK RE++++K L H +
Sbjct: 30 YEIDRTIGKGNFAVVKRATHLVTKAKVAIKIIDKTQLDEENLKKIF-REVQIMKMLCHPH 88
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+IR Q +ET +Y+V EYA G + D + + E RR FKQ+V AV +CH R +
Sbjct: 89 IIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVTAVYFCHCRNI 148
Query: 628 VHRDIKCENLLMDHGLNIKLS 690
VHRD+K ENLL+D LNIK++
Sbjct: 149 VHRDLKAENLLLDANLNIKIA 169
>AC005581-1|AAC33487.1| 462|Homo sapiens R31237_1, partial CDS
protein.
Length = 462
Score = 73.3 bits (172), Expect(2) = 9e-28
Identities = 38/84 (45%), Positives = 52/84 (61%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y L RTIG G++A VK+A +VAIKII K Q L+K RE+ ++KGL H N
Sbjct: 59 YRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPSSLQKLF-REVRIMKGLNHPN 117
Query: 448 LIRFLQAIETTHRVYIVMEYAENG 519
+++ + IET +Y+VMEYA G
Sbjct: 118 IVKLFEVIETEKTLYLVMEYASAG 141
Score = 70.5 bits (165), Expect(2) = 9e-28
Identities = 29/63 (46%), Positives = 42/63 (66%)
Frame = +1
Query: 517 GSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDF 696
G + D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+D NIK++DF
Sbjct: 171 GEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIADF 230
Query: 697 GFA 705
GF+
Sbjct: 231 GFS 233
>BC037303-1|AAH37303.1| 550|Homo sapiens PRKAA1 protein protein.
Length = 550
Score = 121 bits (292), Expect = 2e-27
Identities = 57/146 (39%), Positives = 91/146 (62%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y+LG T+G G++ VKV + +VA+KI+++ + + + REI+ +K +H +
Sbjct: 18 YILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPH 77
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+I+ Q I T +++VMEY G L D I K+ +DE RR F+Q++ VDYCH V
Sbjct: 78 IIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMV 137
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFA 705
VHRD+K EN+L+D +N K++DFG +
Sbjct: 138 VHRDLKPENVLLDAHMNAKIADFGLS 163
>BC012622-1|AAH12622.1| 207|Homo sapiens PRKAA1 protein protein.
Length = 207
Score = 121 bits (292), Expect = 2e-27
Identities = 57/146 (39%), Positives = 91/146 (62%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y+LG T+G G++ VKV + +VA+KI+++ + + + REI+ +K +H +
Sbjct: 18 YILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPH 77
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+I+ Q I T +++VMEY G L D I K+ +DE RR F+Q++ VDYCH V
Sbjct: 78 IIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMV 137
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFA 705
VHRD+K EN+L+D +N K++DFG +
Sbjct: 138 VHRDLKPENVLLDAHMNAKIADFGLS 163
>AB022017-1|BAA36547.1| 550|Homo sapiens AMP-activated protein
kinase alpha-1 protein.
Length = 550
Score = 121 bits (292), Expect = 2e-27
Identities = 57/146 (39%), Positives = 91/146 (62%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y+LG T+G G++ VKV + +VA+KI+++ + + + REI+ +K +H +
Sbjct: 18 YILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPH 77
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+I+ Q I T +++VMEY G L D I K+ +DE RR F+Q++ VDYCH V
Sbjct: 78 IIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMV 137
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFA 705
VHRD+K EN+L+D +N K++DFG +
Sbjct: 138 VHRDLKPENVLLDAHMNAKIADFGLS 163
>BC017306-1|AAH17306.1| 628|Homo sapiens NUAK family, SNF1-like
kinase, 2 protein.
Length = 628
Score = 120 bits (288), Expect = 7e-27
Identities = 60/148 (40%), Positives = 85/148 (57%)
Frame = +1
Query: 262 HGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKH 441
H Y T+G G+Y VK A VAIK I K + + + REIE++ L H
Sbjct: 51 HRYEFLETLGKGTYGKVKKARESSGRL-VAIKSIRKDKIKDEQDLMHIRREIEIMSSLNH 109
Query: 442 ENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHER 621
++I + E + ++ IVMEYA G L D I + Q + E R +F+Q+V AV YCH+
Sbjct: 110 PHIIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQN 169
Query: 622 GVVHRDIKCENLLMDHGLNIKLSDFGFA 705
VVHRD+K EN+L+D NIK++DFG +
Sbjct: 170 RVVHRDLKLENILLDANGNIKIADFGLS 197
>AK074830-1|BAC11234.1| 628|Homo sapiens protein ( Homo sapiens
cDNA FLJ90349 fis, clone NT2RP2003179, weakly similar to
PUTATIVE SERINE/THREONINE-PROTEIN KINASE EMK (EC
2.7.1.-). ).
Length = 628
Score = 120 bits (288), Expect = 7e-27
Identities = 60/148 (40%), Positives = 85/148 (57%)
Frame = +1
Query: 262 HGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKH 441
H Y T+G G+Y VK A VAIK I K + + + REIE++ L H
Sbjct: 51 HRYEFLETLGKGTYGKVKKARESSGRL-VAIKSIRKDKIKDEQDLMHIRREIEIMSSLNH 109
Query: 442 ENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHER 621
++I + E + ++ IVMEYA G L D I + Q + E R +F+Q+V AV YCH+
Sbjct: 110 PHIIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQN 169
Query: 622 GVVHRDIKCENLLMDHGLNIKLSDFGFA 705
VVHRD+K EN+L+D NIK++DFG +
Sbjct: 170 RVVHRDLKLENILLDANGNIKIADFGLS 197
>U06454-1|AAA64745.1| 552|Homo sapiens AMP-activated protein kinase
protein.
Length = 552
Score = 118 bits (284), Expect = 2e-26
Identities = 56/146 (38%), Positives = 89/146 (60%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y+LG T+G G++ VK+ +VA+KI+++ + + + REI+ +K +H +
Sbjct: 16 YVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPH 75
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+I+ Q I T ++VMEY G L D I K ++E RR F+Q++ AVDYCH V
Sbjct: 76 IIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMV 135
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFA 705
VHRD+K EN+L+D +N K++DFG +
Sbjct: 136 VHRDLKPENVLLDAHMNAKIADFGLS 161
>BC069823-1|AAH69823.1| 552|Homo sapiens AMP-activated protein
kinase alpha 2 catalytic subunit protein.
Length = 552
Score = 118 bits (284), Expect = 2e-26
Identities = 56/146 (38%), Positives = 89/146 (60%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y+LG T+G G++ VK+ +VA+KI+++ + + + REI+ +K +H +
Sbjct: 16 YVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPH 75
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+I+ Q I T ++VMEY G L D I K ++E RR F+Q++ AVDYCH V
Sbjct: 76 IIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMV 135
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFA 705
VHRD+K EN+L+D +N K++DFG +
Sbjct: 136 VHRDLKPENVLLDAHMNAKIADFGLS 161
>BC069740-1|AAH69740.1| 552|Homo sapiens AMP-activated protein
kinase alpha 2 catalytic subunit protein.
Length = 552
Score = 118 bits (284), Expect = 2e-26
Identities = 56/146 (38%), Positives = 89/146 (60%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y+LG T+G G++ VK+ +VA+KI+++ + + + REI+ +K +H +
Sbjct: 16 YVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPH 75
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+I+ Q I T ++VMEY G L D I K ++E RR F+Q++ AVDYCH V
Sbjct: 76 IIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMV 135
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFA 705
VHRD+K EN+L+D +N K++DFG +
Sbjct: 136 VHRDLKPENVLLDAHMNAKIADFGLS 161
>BC069680-1|AAH69680.1| 552|Homo sapiens protein kinase,
AMP-activated, alpha 2 catalytic subunit protein.
Length = 552
Score = 118 bits (284), Expect = 2e-26
Identities = 56/146 (38%), Positives = 89/146 (60%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y+LG T+G G++ VK+ +VA+KI+++ + + + REI+ +K +H +
Sbjct: 16 YVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPH 75
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+I+ Q I T ++VMEY G L D I K ++E RR F+Q++ AVDYCH V
Sbjct: 76 IIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMV 135
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFA 705
VHRD+K EN+L+D +N K++DFG +
Sbjct: 136 VHRDLKPENVLLDAHMNAKIADFGLS 161
>AL035705-2|CAC17574.2| 552|Homo sapiens protein kinase,
AMP-activated, alpha 2 catalytic subunit protein.
Length = 552
Score = 118 bits (284), Expect = 2e-26
Identities = 56/146 (38%), Positives = 89/146 (60%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y+LG T+G G++ VK+ +VA+KI+++ + + + REI+ +K +H +
Sbjct: 16 YVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPH 75
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+I+ Q I T ++VMEY G L D I K ++E RR F+Q++ AVDYCH V
Sbjct: 76 IIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMV 135
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFA 705
VHRD+K EN+L+D +N K++DFG +
Sbjct: 136 VHRDLKPENVLLDAHMNAKIADFGLS 161
>AJ271722-1|CAB71146.1| 714|Homo sapiens putative serine/threonine
protein kinase MAK-V protein.
Length = 714
Score = 118 bits (283), Expect = 3e-26
Identities = 60/148 (40%), Positives = 94/148 (63%), Gaps = 2/148 (1%)
Frame = +1
Query: 268 YMLG-RTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGD-YLKKFLPREIEVVKGLKH 441
Y++G R +G GS+A V+ +VAIK+I K +A D Y+ K L RE ++ + ++H
Sbjct: 61 YLIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRH 120
Query: 442 ENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHER 621
N+ + L +ET + Y+VME G+L+ I + + ++E+ RR+ +QL+ AV++ H
Sbjct: 121 PNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLEESEARRYIRQLISAVEHLHRA 180
Query: 622 GVVHRDIKCENLLMDHGLNIKLSDFGFA 705
GVVHRD+K ENLL+D NIKL DFG +
Sbjct: 181 GVVHRDLKIENLLLDEDNNIKLIDFGLS 208
>EF056019-1|ABK30810.1| 552|Homo sapiens AMP-activated alpha 2
subunit protein.
Length = 552
Score = 116 bits (279), Expect = 9e-26
Identities = 55/146 (37%), Positives = 88/146 (60%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y+LG T+G G++ V + +VA+KI+++ + + + REI+ +K +H +
Sbjct: 16 YVLGDTLGVGTFGKVNIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPH 75
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+I+ Q I T ++VMEY G L D I K ++E RR F+Q++ AVDYCH V
Sbjct: 76 IIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMV 135
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFA 705
VHRD+K EN+L+D +N K++DFG +
Sbjct: 136 VHRDLKPENVLLDAHMNAKIADFGLS 161
>AF054621-1|AAC25955.1| 309|Homo sapiens serine/threonine kinase
AIE2 protein.
Length = 309
Score = 115 bits (276), Expect = 2e-25
Identities = 56/173 (32%), Positives = 96/173 (55%)
Frame = +1
Query: 187 SAEPTATVHSGVEAKTERKLTVLESHGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIIS 366
+ E AT + + + + L + +GR +G G + V +A + VA+K++
Sbjct: 16 AGEELATANQTAQQPSSPAMRRLTVDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLF 75
Query: 367 KFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKD 546
K Q + L+ L REIE+ L+H N++R RVY+++EYA G L ++K
Sbjct: 76 KSQIEKEGLEHQLRREIEIQAHLQHPNILRLYNHFHDARRVYLILEYAPRGELYKELQKS 135
Query: 547 QHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 705
+ +DE R ++L +A+ YCH++ V+HRDIK ENLL+ +K++DFG++
Sbjct: 136 EKLDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWS 188
>AB017332-1|BAA76292.1| 309|Homo sapiens Aurora/Ipl1-related kinase
3 protein.
Length = 309
Score = 115 bits (276), Expect = 2e-25
Identities = 56/173 (32%), Positives = 96/173 (55%)
Frame = +1
Query: 187 SAEPTATVHSGVEAKTERKLTVLESHGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIIS 366
+ E AT + + + + L + +GR +G G + V +A + VA+K++
Sbjct: 16 AGEELATANQTAQQPSSPAMRRLTVDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLF 75
Query: 367 KFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKD 546
K Q + L+ L REIE+ L+H N++R RVY+++EYA G L ++K
Sbjct: 76 KSQIEKEGLEHQLRREIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKS 135
Query: 547 QHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 705
+ +DE R ++L +A+ YCH++ V+HRDIK ENLL+ +K++DFG++
Sbjct: 136 EKLDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWS 188
>BC075064-1|AAH75064.2| 275|Homo sapiens AURKC protein protein.
Length = 275
Score = 113 bits (272), Expect = 6e-25
Identities = 56/156 (35%), Positives = 93/156 (59%)
Frame = +1
Query: 238 RKLTVLESHGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREI 417
R+LTV + + +GR +G G + V +A + VA+K++ K Q + L+ L REI
Sbjct: 2 RRLTVDD---FEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREI 58
Query: 418 EVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVE 597
E+ L+H N++R RVY+++EYA G L ++K + +DE R ++L +
Sbjct: 59 EIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELAD 118
Query: 598 AVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 705
A+ YCH++ V+HRDIK ENLL+ +K++DFG++
Sbjct: 119 ALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWS 154
>AY714054-1|AAU04399.1| 306|Homo sapiens aurora-C protein.
Length = 306
Score = 113 bits (272), Expect = 6e-25
Identities = 56/156 (35%), Positives = 93/156 (59%)
Frame = +1
Query: 238 RKLTVLESHGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREI 417
R+LTV + + +GR +G G + V +A + VA+K++ K Q + L+ L REI
Sbjct: 33 RRLTVDD---FEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREI 89
Query: 418 EVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVE 597
E+ L+H N++R RVY+++EYA G L ++K + +DE R ++L +
Sbjct: 90 EIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELAD 149
Query: 598 AVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 705
A+ YCH++ V+HRDIK ENLL+ +K++DFG++
Sbjct: 150 ALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWS 185
>AY661554-1|AAT64422.1| 290|Homo sapiens aurora/Ipl1-related kinase
3 transcript variant 1 protein.
Length = 290
Score = 113 bits (272), Expect = 6e-25
Identities = 56/156 (35%), Positives = 93/156 (59%)
Frame = +1
Query: 238 RKLTVLESHGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREI 417
R+LTV + + +GR +G G + V +A + VA+K++ K Q + L+ L REI
Sbjct: 17 RRLTVDD---FEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREI 73
Query: 418 EVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVE 597
E+ L+H N++R RVY+++EYA G L ++K + +DE R ++L +
Sbjct: 74 EIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELAD 133
Query: 598 AVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 705
A+ YCH++ V+HRDIK ENLL+ +K++DFG++
Sbjct: 134 ALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWS 169
>AF059681-1|AAC77369.1| 275|Homo sapiens serine/threonine kinase 13
protein.
Length = 275
Score = 112 bits (269), Expect = 1e-24
Identities = 55/156 (35%), Positives = 93/156 (59%)
Frame = +1
Query: 238 RKLTVLESHGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREI 417
R+LTV + + +GR +G G + V +A + VA+K++ K Q + L+ L REI
Sbjct: 2 RRLTVDD---FEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREI 58
Query: 418 EVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVE 597
E+ L+H N++R RVY+++EYA G L ++K + +DE R +++ +
Sbjct: 59 EIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEEVAD 118
Query: 598 AVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 705
A+ YCH++ V+HRDIK ENLL+ +K++DFG++
Sbjct: 119 ALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWS 154
>U22456-1|AAA64850.1| 174|Homo sapiens AMP-activated protein kinase
homolog protein.
Length = 174
Score = 110 bits (265), Expect = 4e-24
Identities = 52/137 (37%), Positives = 84/137 (61%)
Frame = +1
Query: 295 GSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIE 474
G++ VKV + +VA+KI+++ + + + REI+ +K +H ++I+ Q I
Sbjct: 1 GAFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVIS 60
Query: 475 TTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCEN 654
T +++VMEY G L D I K+ +DE RR F+Q++ VDYCH VVHRD+K EN
Sbjct: 61 TPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPEN 120
Query: 655 LLMDHGLNIKLSDFGFA 705
+L+D +N K++DFG +
Sbjct: 121 VLLDAHMNAKIADFGLS 137
>AF159295-1|AAD48007.1| 752|Homo sapiens serine/threonine protein
kinase Kp78 splice variant CTAK75a protein.
Length = 752
Score = 110 bits (264), Expect = 6e-24
Identities = 63/169 (37%), Positives = 93/169 (55%), Gaps = 23/169 (13%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y L +TIG G++A VK+A +VAIKII K Q L+K RE+ ++K L H N
Sbjct: 56 YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLF-REVRIMKILNHPN 114
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQ------------- 588
+++ + IET +Y++MEYA G + D + + E R F+Q
Sbjct: 115 IVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGKMKEKEARSKFRQGCQAGQTIKVQVS 174
Query: 589 ----------LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 705
+V AV YCH++ +VHRD+K ENLL+D +NIK++DFGF+
Sbjct: 175 FDLLSLMFTFIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFS 223
>D79997-1|BAA11492.2| 656|Homo sapiens KIAA0175 protein.
Length = 656
Score = 107 bits (257), Expect = 4e-23
Identities = 56/144 (38%), Positives = 81/144 (56%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y L TIG+G +A VK+A VAIKI+ K D + + EIE +K L+H++
Sbjct: 16 YELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGSDLPR--IKTEIEALKNLRHQH 73
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+ + +ET +++++V+EY G L D I + E R F+Q+V AV Y H +G
Sbjct: 74 ICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGY 133
Query: 628 VHRDIKCENLLMDHGLNIKLSDFG 699
HRD+K ENLL D +KL DFG
Sbjct: 134 AHRDLKPENLLFDEYHKLKLIDFG 157
>BC014039-1|AAH14039.1| 651|Homo sapiens maternal embryonic leucine
zipper kinase protein.
Length = 651
Score = 107 bits (257), Expect = 4e-23
Identities = 56/144 (38%), Positives = 81/144 (56%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y L TIG+G +A VK+A VAIKI+ K D + + EIE +K L+H++
Sbjct: 11 YELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGSDLPR--IKTEIEALKNLRHQH 68
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+ + +ET +++++V+EY G L D I + E R F+Q+V AV Y H +G
Sbjct: 69 ICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGY 128
Query: 628 VHRDIKCENLLMDHGLNIKLSDFG 699
HRD+K ENLL D +KL DFG
Sbjct: 129 AHRDLKPENLLFDEYHKLKLIDFG 152
>AL442063-1|CAI16995.2| 651|Homo sapiens maternal embryonic leucine
zipper kinase protein.
Length = 651
Score = 107 bits (257), Expect = 4e-23
Identities = 56/144 (38%), Positives = 81/144 (56%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y L TIG+G +A VK+A VAIKI+ K D + + EIE +K L+H++
Sbjct: 11 YELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGSDLPR--IKTEIEALKNLRHQH 68
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+ + +ET +++++V+EY G L D I + E R F+Q+V AV Y H +G
Sbjct: 69 ICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGY 128
Query: 628 VHRDIKCENLLMDHGLNIKLSDFG 699
HRD+K ENLL D +KL DFG
Sbjct: 129 AHRDLKPENLLFDEYHKLKLIDFG 152
>AL354932-1|CAI11034.2| 651|Homo sapiens maternal embryonic leucine
zipper kinase protein.
Length = 651
Score = 107 bits (257), Expect = 4e-23
Identities = 56/144 (38%), Positives = 81/144 (56%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y L TIG+G +A VK+A VAIKI+ K D + + EIE +K L+H++
Sbjct: 11 YELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGSDLPR--IKTEIEALKNLRHQH 68
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+ + +ET +++++V+EY G L D I + E R F+Q+V AV Y H +G
Sbjct: 69 ICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGY 128
Query: 628 VHRDIKCENLLMDHGLNIKLSDFG 699
HRD+K ENLL D +KL DFG
Sbjct: 129 AHRDLKPENLLFDEYHKLKLIDFG 152
>AK222811-1|BAD96531.1| 651|Homo sapiens maternal embryonic leucine
zipper kinase variant protein.
Length = 651
Score = 107 bits (257), Expect = 4e-23
Identities = 56/144 (38%), Positives = 81/144 (56%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y L TIG+G +A VK+A VAIKI+ K D + + EIE +K L+H++
Sbjct: 11 YELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGSDLPR--IKTEIEALKNLRHQH 68
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+ + +ET +++++V+EY G L D I + E R F+Q+V AV Y H +G
Sbjct: 69 ICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGY 128
Query: 628 VHRDIKCENLLMDHGLNIKLSDFG 699
HRD+K ENLL D +KL DFG
Sbjct: 129 AHRDLKPENLLFDEYHKLKLIDFG 152
>BC048980-1|AAH48980.1| 574|Homo sapiens protein kinase,
AMP-activated, alpha 1 catalytic subunit protein.
Length = 574
Score = 107 bits (256), Expect = 5e-23
Identities = 57/161 (35%), Positives = 92/161 (57%), Gaps = 15/161 (9%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y+LG T+G G++ VKV + +VA+KI+++ + + + REI+ +K +H +
Sbjct: 27 YILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPH 86
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKD---------------QHIDETRGRRWF 582
+I+ Q I T +++VMEY G L D I K+ + +DE RR F
Sbjct: 87 IIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRKSDVPGVVKTGSTKELDEKESRRLF 146
Query: 583 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 705
+Q++ VDYCH VVHRD+K EN+L+D +N K++DFG +
Sbjct: 147 QQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLS 187
>D84212-1|BAA23592.1| 402|Homo sapiens aurora/IPL1-related kinase
protein.
Length = 402
Score = 105 bits (253), Expect = 1e-22
Identities = 51/165 (30%), Positives = 91/165 (55%)
Frame = +1
Query: 211 HSGVEAKTERKLTVLESHGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDY 390
H + K +++ LE + +GR +G G + V +A + +A+K++ K Q
Sbjct: 115 HQNRKMKNQKEAVALED--FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAG 172
Query: 391 LKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRG 570
++ L RE+E+ L+H N++R RVY+++EYA G++ ++K DE R
Sbjct: 173 VEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRT 232
Query: 571 RRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 705
+ ++ A+ YCH + V+HRDIK ENLL+ +K++DFG++
Sbjct: 233 ANLYNRIANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS 277
>BT019534-1|AAV38341.1| 344|Homo sapiens serine/threonine kinase 12
protein.
Length = 344
Score = 105 bits (252), Expect = 2e-22
Identities = 56/182 (30%), Positives = 96/182 (52%), Gaps = 4/182 (2%)
Frame = +1
Query: 172 VLGEMSAEPTATVHSGVEAKTERKLTVLESH----GYMLGRTIGSGSYATVKVASSDRHN 339
++ + +PTA V + +L H + +GR +G G + V +A + +
Sbjct: 41 LMSRSNVQPTAAPGQKVMENSSGTPDILTRHFTIDDFEIGRPLGKGKFGNVYLAREKKSH 100
Query: 340 CQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENG 519
VA+K++ K Q + ++ L REIE+ L H N++R R+Y+++EYA G
Sbjct: 101 FIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRG 160
Query: 520 SLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFG 699
L ++K DE R ++L +A+ YCH + V+HRDIK ENLL+ +K++DFG
Sbjct: 161 ELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFG 220
Query: 700 FA 705
++
Sbjct: 221 WS 222
>BC080581-1|AAH80581.1| 344|Homo sapiens aurora kinase B protein.
Length = 344
Score = 105 bits (252), Expect = 2e-22
Identities = 56/182 (30%), Positives = 96/182 (52%), Gaps = 4/182 (2%)
Frame = +1
Query: 172 VLGEMSAEPTATVHSGVEAKTERKLTVLESH----GYMLGRTIGSGSYATVKVASSDRHN 339
++ + +PTA V + +L H + +GR +G G + V +A + +
Sbjct: 41 LMSRSNVQPTAAPGQKVMENSSGTPDILTRHFTIDDFEIGRPLGKGKFGNVYLAREKKSH 100
Query: 340 CQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENG 519
VA+K++ K Q + ++ L REIE+ L H N++R R+Y+++EYA G
Sbjct: 101 FIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRG 160
Query: 520 SLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFG 699
L ++K DE R ++L +A+ YCH + V+HRDIK ENLL+ +K++DFG
Sbjct: 161 ELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFG 220
Query: 700 FA 705
++
Sbjct: 221 WS 222
>BC009751-1|AAH09751.1| 344|Homo sapiens aurora kinase B protein.
Length = 344
Score = 105 bits (252), Expect = 2e-22
Identities = 56/182 (30%), Positives = 96/182 (52%), Gaps = 4/182 (2%)
Frame = +1
Query: 172 VLGEMSAEPTATVHSGVEAKTERKLTVLESH----GYMLGRTIGSGSYATVKVASSDRHN 339
++ + +PTA V + +L H + +GR +G G + V +A + +
Sbjct: 41 LMSRSNVQPTAAPGQKVMENSSGTPDILTRHFTIDDFEIGRPLGKGKFGNVYLAREKKSH 100
Query: 340 CQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENG 519
VA+K++ K Q + ++ L REIE+ L H N++R R+Y+++EYA G
Sbjct: 101 FIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRG 160
Query: 520 SLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFG 699
L ++K DE R ++L +A+ YCH + V+HRDIK ENLL+ +K++DFG
Sbjct: 161 ELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFG 220
Query: 700 FA 705
++
Sbjct: 221 WS 222
>BC000442-1|AAH00442.3| 344|Homo sapiens aurora kinase B protein.
Length = 344
Score = 105 bits (252), Expect = 2e-22
Identities = 56/182 (30%), Positives = 96/182 (52%), Gaps = 4/182 (2%)
Frame = +1
Query: 172 VLGEMSAEPTATVHSGVEAKTERKLTVLESH----GYMLGRTIGSGSYATVKVASSDRHN 339
++ + +PTA V + +L H + +GR +G G + V +A + +
Sbjct: 41 LMSRSNVQPTAAPGQKVMENSSGTPDILTRHFTIDDFEIGRPLGKGKFGNVYLAREKKSH 100
Query: 340 CQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENG 519
VA+K++ K Q + ++ L REIE+ L H N++R R+Y+++EYA G
Sbjct: 101 FIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRG 160
Query: 520 SLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFG 699
L ++K DE R ++L +A+ YCH + V+HRDIK ENLL+ +K++DFG
Sbjct: 161 ELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFG 220
Query: 700 FA 705
++
Sbjct: 221 WS 222
>AF008552-1|AAC12709.1| 344|Homo sapiens aurora-related kinase 2
protein.
Length = 344
Score = 105 bits (252), Expect = 2e-22
Identities = 56/182 (30%), Positives = 96/182 (52%), Gaps = 4/182 (2%)
Frame = +1
Query: 172 VLGEMSAEPTATVHSGVEAKTERKLTVLESH----GYMLGRTIGSGSYATVKVASSDRHN 339
++ + +PTA V + +L H + +GR +G G + V +A + +
Sbjct: 41 LMSRSNVQPTAAPGQKVMENSSGTPDILTRHFTIDDFEIGRPLGKGKFGNVYLAREKKSH 100
Query: 340 CQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENG 519
VA+K++ K Q + ++ L REIE+ L H N++R R+Y+++EYA G
Sbjct: 101 FIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRG 160
Query: 520 SLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFG 699
L ++K DE R ++L +A+ YCH + V+HRDIK ENLL+ +K++DFG
Sbjct: 161 ELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFG 220
Query: 700 FA 705
++
Sbjct: 221 WS 222
>AB011450-1|BAA32136.1| 344|Homo sapiens aurora and IPL1-like
midbody-associated protein kinase-1 protein.
Length = 344
Score = 105 bits (252), Expect = 2e-22
Identities = 56/182 (30%), Positives = 96/182 (52%), Gaps = 4/182 (2%)
Frame = +1
Query: 172 VLGEMSAEPTATVHSGVEAKTERKLTVLESH----GYMLGRTIGSGSYATVKVASSDRHN 339
++ + +PTA V + +L H + +GR +G G + V +A + +
Sbjct: 41 LMSRSNVQPTAAPGQKVMENSSGTPDILTRHFTIDDFEIGRPLGKGKFGNVYLAREKKSH 100
Query: 340 CQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENG 519
VA+K++ K Q + ++ L REIE+ L H N++R R+Y+++EYA G
Sbjct: 101 FIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRG 160
Query: 520 SLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFG 699
L ++K DE R ++L +A+ YCH + V+HRDIK ENLL+ +K++DFG
Sbjct: 161 ELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFG 220
Query: 700 FA 705
++
Sbjct: 221 WS 222
>AB011446-1|BAA82709.1| 343|Homo sapiens Aik2 protein.
Length = 343
Score = 105 bits (252), Expect = 2e-22
Identities = 56/182 (30%), Positives = 96/182 (52%), Gaps = 4/182 (2%)
Frame = +1
Query: 172 VLGEMSAEPTATVHSGVEAKTERKLTVLESH----GYMLGRTIGSGSYATVKVASSDRHN 339
++ + +PTA V + +L H + +GR +G G + V +A + +
Sbjct: 41 LMSRSNVQPTAAPGQKVMENSSGTPDILTRHFTIDDFEIGRPLGKGKFGNVYLAREKKSH 100
Query: 340 CQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENG 519
VA+K++ K Q + ++ L REIE+ L H N++R R+Y+++EYA G
Sbjct: 101 FIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRG 160
Query: 520 SLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFG 699
L ++K DE R ++L +A+ YCH + V+HRDIK ENLL+ +K++DFG
Sbjct: 161 ELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFG 220
Query: 700 FA 705
++
Sbjct: 221 WS 222
>BC031231-1|AAH31231.1| 514|Homo sapiens serine/threonine kinase 33
protein.
Length = 514
Score = 105 bits (251), Expect = 2e-22
Identities = 56/155 (36%), Positives = 86/155 (55%), Gaps = 9/155 (5%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y GR +G GS+ V A+ + AIK ++K +A G K L RE+ ++K +KHE+
Sbjct: 116 YTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEKA-GSSAVKLLEREVNILKSVKHEH 174
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+I Q ET ++Y+VME E+G L +I+ + H E R + L A+ Y H +
Sbjct: 175 IIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDI 234
Query: 628 VHRDIKCENLLM---------DHGLNIKLSDFGFA 705
VHRD+K EN+++ + LNIK++DFG A
Sbjct: 235 VHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLA 269
>AK093251-1|BAC04109.1| 514|Homo sapiens protein ( Homo sapiens
cDNA FLJ35932 fis, clone TESTI2011286, weakly similar to
MYOSIN LIGHT CHAIN KINASE (EC 2.7.1.117). ).
Length = 514
Score = 105 bits (251), Expect = 2e-22
Identities = 56/155 (36%), Positives = 86/155 (55%), Gaps = 9/155 (5%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y GR +G GS+ V A+ + AIK ++K +A G K L RE+ ++K +KHE+
Sbjct: 116 YTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEKA-GSSAVKLLEREVNILKSVKHEH 174
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+I Q ET ++Y+VME E+G L +I+ + H E R + L A+ Y H +
Sbjct: 175 IIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDI 234
Query: 628 VHRDIKCENLLM---------DHGLNIKLSDFGFA 705
VHRD+K EN+++ + LNIK++DFG A
Sbjct: 235 VHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLA 269
>AJ303380-1|CAC29064.1| 514|Homo sapiens serine/threonine kinase 33
protein.
Length = 514
Score = 105 bits (251), Expect = 2e-22
Identities = 56/155 (36%), Positives = 86/155 (55%), Gaps = 9/155 (5%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y GR +G GS+ V A+ + AIK ++K +A G K L RE+ ++K +KHE+
Sbjct: 116 YTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEKA-GSSAVKLLEREVNILKSVKHEH 174
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+I Q ET ++Y+VME E+G L +I+ + H E R + L A+ Y H +
Sbjct: 175 IIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDI 234
Query: 628 VHRDIKCENLLM---------DHGLNIKLSDFGFA 705
VHRD+K EN+++ + LNIK++DFG A
Sbjct: 235 VHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLA 269
>AY505124-1|AAS86442.1| 778|Homo sapiens protein kinase SAD-B
protein.
Length = 778
Score = 104 bits (249), Expect = 4e-22
Identities = 50/146 (34%), Positives = 85/146 (58%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y L +T+G G VK+ +VAIKI+++ + L K + REI ++K ++H +
Sbjct: 34 YRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREKLSESVLMK-VEREIAILKLIEHPH 92
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+++ E +Y+V+E+ G L D + K + R++F+Q+V A+D+CH +
Sbjct: 93 VLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCHSYSI 152
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFA 705
HRD+K ENLL+D NI+++DFG A
Sbjct: 153 CHRDLKPENLLLDEKNNIRIADFGMA 178
>AY458602-1|AAS10354.1| 778|Homo sapiens SAD1 kinase protein.
Length = 778
Score = 104 bits (249), Expect = 4e-22
Identities = 50/146 (34%), Positives = 85/146 (58%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y L +T+G G VK+ +VAIKI+++ + L K + REI ++K ++H +
Sbjct: 34 YRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREKLSESVLMK-VEREIAILKLIEHPH 92
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+++ E +Y+V+E+ G L D + K + R++F+Q+V A+D+CH +
Sbjct: 93 VLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCHSYSI 152
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFA 705
HRD+K ENLL+D NI+++DFG A
Sbjct: 153 CHRDLKPENLLLDEKNNIRIADFGMA 178
>AF479827-1|AAL87698.1| 778|Homo sapiens protein kinase-like
protein protein.
Length = 778
Score = 104 bits (249), Expect = 4e-22
Identities = 50/146 (34%), Positives = 85/146 (58%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y L +T+G G VK+ +VAIKI+++ + L K + REI ++K ++H +
Sbjct: 34 YRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREKLSESVLMK-VEREIAILKLIEHPH 92
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+++ E +Y+V+E+ G L D + K + R++F+Q+V A+D+CH +
Sbjct: 93 VLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCHSYSI 152
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFA 705
HRD+K ENLL+D NI+++DFG A
Sbjct: 153 CHRDLKPENLLLDEKNNIRIADFGMA 178
>AF479826-1|AAL87697.1| 794|Homo sapiens putative serine/threonine
protein kinase protein.
Length = 794
Score = 104 bits (249), Expect = 4e-22
Identities = 50/146 (34%), Positives = 85/146 (58%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y L +T+G G VK+ +VAIKI+++ + L K + REI ++K ++H +
Sbjct: 50 YRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREKLSESVLMK-VEREIAILKLIEHPH 108
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+++ E +Y+V+E+ G L D + K + R++F+Q+V A+D+CH +
Sbjct: 109 VLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCHSYSI 168
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFA 705
HRD+K ENLL+D NI+++DFG A
Sbjct: 169 CHRDLKPENLLLDEKNNIRIADFGMA 194
>BC036422-1|AAH36422.1| 436|Homo sapiens hypothetical protein
MGC42105 protein.
Length = 436
Score = 103 bits (248), Expect = 5e-22
Identities = 55/162 (33%), Positives = 91/162 (56%), Gaps = 1/162 (0%)
Frame = +1
Query: 223 EAKTERKLTVLESHG-YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKK 399
+ K R++T+ + G Y + IGSG+++ VK+ +VAIKI+ K + ++
Sbjct: 58 DEKVVREITLGKRIGFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLD-QKTQR 116
Query: 400 FLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRW 579
L REI ++ L H N+IR + +ET ++++VMEYA G L I + + E +
Sbjct: 117 LLSREISSMEKLHHPNIIRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLI 176
Query: 580 FKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 705
F Q+V AV + HE ++HRD+K EN+ +K+ DFGF+
Sbjct: 177 FSQIVSAVKHMHENQIIHRDLKAENVFYTSNTCVKVGDFGFS 218
>BC013300-1|AAH13300.2| 371|Homo sapiens AURKB protein protein.
Length = 371
Score = 103 bits (247), Expect = 6e-22
Identities = 50/146 (34%), Positives = 84/146 (57%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
+ +GR +G G + V +A + + VA+K++ K Q + ++ L REIE+ L H N
Sbjct: 104 FEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPN 163
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
++R R+Y+++EYA G L ++K DE R ++L +A+ YCH + V
Sbjct: 164 ILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKKV 223
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFA 705
+HRDIK ENLL+ +K++DFG++
Sbjct: 224 IHRDIKPENLLLGLKGELKIADFGWS 249
>AY505125-1|AAS86443.1| 696|Homo sapiens protein kinase SAD-A
protein.
Length = 696
Score = 103 bits (247), Expect = 6e-22
Identities = 49/146 (33%), Positives = 85/146 (58%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y L +T+G G VK+ +VAIKI+++ + L K + REI ++K ++H +
Sbjct: 19 YRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNREKLSESVLMK-VEREIAILKLIEHPH 77
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+++ E +Y+V+E+ G L D + K + R++F+Q++ A+D+CH +
Sbjct: 78 VLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSI 137
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFA 705
HRD+K ENLL+D NI+++DFG A
Sbjct: 138 CHRDLKPENLLLDEKNNIRIADFGMA 163
>AY166857-1|AAN87839.1| 668|Homo sapiens serine/threonine protein
kinase isoform protein.
Length = 668
Score = 103 bits (247), Expect = 6e-22
Identities = 49/146 (33%), Positives = 85/146 (58%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y L +T+G G VK+ +VAIKI+++ + L K + REI ++K ++H +
Sbjct: 19 YRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNREKLSESVLMK-VEREIAILKLIEHPH 77
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+++ E +Y+V+E+ G L D + K + R++F+Q++ A+D+CH +
Sbjct: 78 VLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSI 137
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFA 705
HRD+K ENLL+D NI+++DFG A
Sbjct: 138 CHRDLKPENLLLDEKNNIRIADFGMA 163
>AF533880-1|AAP97727.1| 674|Homo sapiens putative serine/threonine
protein kinase variant B3 protein.
Length = 674
Score = 103 bits (247), Expect = 6e-22
Identities = 49/146 (33%), Positives = 85/146 (58%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y L +T+G G VK+ +VAIKI+++ + L K + REI ++K ++H +
Sbjct: 19 YRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNREKLSESVLMK-VEREIAILKLIEHPH 77
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+++ E +Y+V+E+ G L D + K + R++F+Q++ A+D+CH +
Sbjct: 78 VLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSI 137
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFA 705
HRD+K ENLL+D NI+++DFG A
Sbjct: 138 CHRDLKPENLLLDEKNNIRIADFGMA 163
>AF533879-1|AAP97726.1| 736|Homo sapiens putative serine/threonine
protein kinase variant C protein.
Length = 736
Score = 103 bits (247), Expect = 6e-22
Identities = 49/146 (33%), Positives = 85/146 (58%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y L +T+G G VK+ +VAIKI+++ + L K + REI ++K ++H +
Sbjct: 19 YRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNREKLSESVLMK-VEREIAILKLIEHPH 77
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+++ E +Y+V+E+ G L D + K + R++F+Q++ A+D+CH +
Sbjct: 78 VLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSI 137
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFA 705
HRD+K ENLL+D NI+++DFG A
Sbjct: 138 CHRDLKPENLLLDEKNNIRIADFGMA 163
>AF533878-1|AAP97725.1| 674|Homo sapiens putative serine/threonine
protein kinase variant B2 protein.
Length = 674
Score = 103 bits (247), Expect = 6e-22
Identities = 49/146 (33%), Positives = 85/146 (58%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y L +T+G G VK+ +VAIKI+++ + L K + REI ++K ++H +
Sbjct: 19 YRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNREKLSESVLMK-VEREIAILKLIEHPH 77
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+++ E +Y+V+E+ G L D + K + R++F+Q++ A+D+CH +
Sbjct: 78 VLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSI 137
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFA 705
HRD+K ENLL+D NI+++DFG A
Sbjct: 138 CHRDLKPENLLLDEKNNIRIADFGMA 163
>AF533877-1|AAP97724.1| 674|Homo sapiens putative serine/threonine
protein kinase variant B1 protein.
Length = 674
Score = 103 bits (247), Expect = 6e-22
Identities = 49/146 (33%), Positives = 85/146 (58%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y L +T+G G VK+ +VAIKI+++ + L K + REI ++K ++H +
Sbjct: 19 YRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNREKLSESVLMK-VEREIAILKLIEHPH 77
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+++ E +Y+V+E+ G L D + K + R++F+Q++ A+D+CH +
Sbjct: 78 VLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSI 137
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFA 705
HRD+K ENLL+D NI+++DFG A
Sbjct: 138 CHRDLKPENLLLDEKNNIRIADFGMA 163
>AF533876-1|AAP97723.1| 668|Homo sapiens putative serine/threonine
protein kinase variant A protein.
Length = 668
Score = 103 bits (247), Expect = 6e-22
Identities = 49/146 (33%), Positives = 85/146 (58%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y L +T+G G VK+ +VAIKI+++ + L K + REI ++K ++H +
Sbjct: 19 YRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNREKLSESVLMK-VEREIAILKLIEHPH 77
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+++ E +Y+V+E+ G L D + K + R++F+Q++ A+D+CH +
Sbjct: 78 VLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSI 137
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFA 705
HRD+K ENLL+D NI+++DFG A
Sbjct: 138 CHRDLKPENLLLDEKNNIRIADFGMA 163
>AF004022-1|AAB65786.1| 347|Homo sapiens protein kinase protein.
Length = 347
Score = 103 bits (246), Expect = 8e-22
Identities = 58/185 (31%), Positives = 97/185 (52%), Gaps = 7/185 (3%)
Frame = +1
Query: 172 VLGEMSAEPTATVHSGVEAKTERKLTVLESH----GYMLGRTIGSGSYATVKVASSDRHN 339
++ + +PTA V + +L H + +GR +G G + V +A + +
Sbjct: 41 LMSRSNVQPTAAPGQKVMENSSGTPDILTRHFTIDDFEIGRPLGKGKFGNVYLAREKKSH 100
Query: 340 CQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENG 519
VA+K++ K Q + ++ L REIE+ L H N++R R+Y+++EYA G
Sbjct: 101 FIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRG 160
Query: 520 SLLDIIRKDQHIDETRG---RRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLS 690
L + K DE R RR ++L +A+ YCH + V+HRDIK ENLL+ +K++
Sbjct: 161 MLYKELHKTCTFDEQRTATVRRIMEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIA 220
Query: 691 DFGFA 705
DFG++
Sbjct: 221 DFGWS 225
>BC027464-1|AAH27464.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 102 bits (245), Expect = 1e-21
Identities = 48/146 (32%), Positives = 83/146 (56%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
+ +GR +G G + V +A + +A+K++ K Q ++ L RE+E+ L+H N
Sbjct: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
++R RVY+++EYA G++ ++K DE R + +L A+ YCH + V
Sbjct: 193 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRV 252
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFA 705
+HRDIK ENLL+ +K++DFG++
Sbjct: 253 IHRDIKPENLLLGSAGELKIADFGWS 278
>BC006423-1|AAH06423.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 102 bits (245), Expect = 1e-21
Identities = 48/146 (32%), Positives = 83/146 (56%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
+ +GR +G G + V +A + +A+K++ K Q ++ L RE+E+ L+H N
Sbjct: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
++R RVY+++EYA G++ ++K DE R + +L A+ YCH + V
Sbjct: 193 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRV 252
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFA 705
+HRDIK ENLL+ +K++DFG++
Sbjct: 253 IHRDIKPENLLLGSAGELKIADFGWS 278
>BC002499-1|AAH02499.1| 403|Homo sapiens AURKA protein protein.
Length = 403
Score = 102 bits (245), Expect = 1e-21
Identities = 48/146 (32%), Positives = 83/146 (56%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
+ +GR +G G + V +A + +A+K++ K Q ++ L RE+E+ L+H N
Sbjct: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
++R RVY+++EYA G++ ++K DE R + +L A+ YCH + V
Sbjct: 193 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRV 252
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFA 705
+HRDIK ENLL+ +K++DFG++
Sbjct: 253 IHRDIKPENLLLGSAGELKIADFGWS 278
>BC001280-1|AAH01280.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 102 bits (245), Expect = 1e-21
Identities = 48/146 (32%), Positives = 83/146 (56%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
+ +GR +G G + V +A + +A+K++ K Q ++ L RE+E+ L+H N
Sbjct: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
++R RVY+++EYA G++ ++K DE R + +L A+ YCH + V
Sbjct: 193 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRV 252
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFA 705
+HRDIK ENLL+ +K++DFG++
Sbjct: 253 IHRDIKPENLLLGSAGELKIADFGWS 278
>AL121914-4|CAM45838.1| 347|Homo sapiens aurora kinase A protein.
Length = 347
Score = 102 bits (245), Expect = 1e-21
Identities = 48/146 (32%), Positives = 83/146 (56%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
+ +GR +G G + V +A + +A+K++ K Q ++ L RE+E+ L+H N
Sbjct: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
++R RVY+++EYA G++ ++K DE R + +L A+ YCH + V
Sbjct: 193 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRV 252
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFA 705
+HRDIK ENLL+ +K++DFG++
Sbjct: 253 IHRDIKPENLLLGSAGELKIADFGWS 278
>AL121914-3|CAC12717.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 102 bits (245), Expect = 1e-21
Identities = 48/146 (32%), Positives = 83/146 (56%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
+ +GR +G G + V +A + +A+K++ K Q ++ L RE+E+ L+H N
Sbjct: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
++R RVY+++EYA G++ ++K DE R + +L A+ YCH + V
Sbjct: 193 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRV 252
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFA 705
+HRDIK ENLL+ +K++DFG++
Sbjct: 253 IHRDIKPENLLLGSAGELKIADFGWS 278
>AF195947-1|AAF29508.1| 403|Homo sapiens STK15 serine/threonine
kinase protein.
Length = 403
Score = 102 bits (245), Expect = 1e-21
Identities = 48/146 (32%), Positives = 83/146 (56%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
+ +GR +G G + V +A + +A+K++ K Q ++ L RE+E+ L+H N
Sbjct: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
++R RVY+++EYA G++ ++K DE R + +L A+ YCH + V
Sbjct: 193 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRV 252
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFA 705
+HRDIK ENLL+ +K++DFG++
Sbjct: 253 IHRDIKPENLLLGSAGELKIADFGWS 278
>AF011468-1|AAC63902.1| 403|Homo sapiens serine/threonine kinase
protein.
Length = 403
Score = 102 bits (245), Expect = 1e-21
Identities = 48/146 (32%), Positives = 83/146 (56%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
+ +GR +G G + V +A + +A+K++ K Q ++ L RE+E+ L+H N
Sbjct: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
++R RVY+++EYA G++ ++K DE R + +L A+ YCH + V
Sbjct: 193 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRV 252
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFA 705
+HRDIK ENLL+ +K++DFG++
Sbjct: 253 IHRDIKPENLLLGSAGELKIADFGWS 278
>AF008551-1|AAC12708.1| 403|Homo sapiens aurora-related kinase 1
protein.
Length = 403
Score = 102 bits (245), Expect = 1e-21
Identities = 48/146 (32%), Positives = 83/146 (56%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
+ +GR +G G + V +A + +A+K++ K Q ++ L RE+E+ L+H N
Sbjct: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
++R RVY+++EYA G++ ++K DE R + +L A+ YCH + V
Sbjct: 193 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRV 252
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFA 705
+HRDIK ENLL+ +K++DFG++
Sbjct: 253 IHRDIKPENLLLGSAGELKIADFGWS 278
>Y15056-1|CAA75341.1| 556|Homo sapiens PkB kinase protein.
Length = 556
Score = 101 bits (243), Expect = 2e-21
Identities = 53/174 (30%), Positives = 95/174 (54%)
Frame = +1
Query: 187 SAEPTATVHSGVEAKTERKLTVLESHGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIIS 366
+AEP S A+ + + G+ +G GS++TV +A + + AIKI+
Sbjct: 55 AAEPRPGAGSLQHAQPPPQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILE 114
Query: 367 KFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKD 546
K + ++ RE +V+ L H ++ + ++Y + YA+NG LL IRK
Sbjct: 115 KRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKI 174
Query: 547 QHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFAR 708
DET R + ++V A++Y H +G++HRD+K EN+L++ ++I+++DFG A+
Sbjct: 175 GSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAK 228
>CR536517-1|CAG38755.1| 556|Homo sapiens PDPK1 protein.
Length = 556
Score = 101 bits (243), Expect = 2e-21
Identities = 53/174 (30%), Positives = 95/174 (54%)
Frame = +1
Query: 187 SAEPTATVHSGVEAKTERKLTVLESHGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIIS 366
+AEP S A+ + + G+ +G GS++TV +A + + AIKI+
Sbjct: 55 AAEPRPGAGSLQHAQPPPQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILE 114
Query: 367 KFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKD 546
K + ++ RE +V+ L H ++ + ++Y + YA+NG LL IRK
Sbjct: 115 KRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKI 174
Query: 547 QHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFAR 708
DET R + ++V A++Y H +G++HRD+K EN+L++ ++I+++DFG A+
Sbjct: 175 GSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAK 228
>BC012103-1|AAH12103.1| 556|Homo sapiens 3-phosphoinositide
dependent protein kinase-1 protein.
Length = 556
Score = 101 bits (243), Expect = 2e-21
Identities = 53/174 (30%), Positives = 95/174 (54%)
Frame = +1
Query: 187 SAEPTATVHSGVEAKTERKLTVLESHGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIIS 366
+AEP S A+ + + G+ +G GS++TV +A + + AIKI+
Sbjct: 55 AAEPRPGAGSLQHAQPPPQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILE 114
Query: 367 KFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKD 546
K + ++ RE +V+ L H ++ + ++Y + YA+NG LL IRK
Sbjct: 115 KRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKI 174
Query: 547 QHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFAR 708
DET R + ++V A++Y H +G++HRD+K EN+L++ ++I+++DFG A+
Sbjct: 175 GSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAK 228
>AK027302-1|BAB55026.1| 208|Homo sapiens protein ( Homo sapiens
cDNA FLJ14396 fis, clone HEMBA1003291, moderately
similar to SNF1-RELATED PROTEIN KINASE KIN10 (EC
2.7.1.-). ).
Length = 208
Score = 101 bits (243), Expect = 2e-21
Identities = 49/128 (38%), Positives = 72/128 (56%)
Frame = +1
Query: 262 HGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKH 441
H Y L T+G G+Y VK A+ VAIK + K + + + REIE++ L H
Sbjct: 53 HRYELQETLGKGTYGKVKRATERFSGRVVAIKSVRKDKIKDEQDMVHIRREIEIMSSLNH 112
Query: 442 ENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHER 621
++I + E ++ I+MEYA G L D I + + + E R +F+Q+V AV YCH+
Sbjct: 113 PHIISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCHKN 172
Query: 622 GVVHRDIK 645
GVVHRD+K
Sbjct: 173 GVVHRDLK 180
>AF017995-1|AAC51825.1| 556|Homo sapiens 3-phosphoinositide
dependent protein kinase-1 protein.
Length = 556
Score = 101 bits (243), Expect = 2e-21
Identities = 53/174 (30%), Positives = 95/174 (54%)
Frame = +1
Query: 187 SAEPTATVHSGVEAKTERKLTVLESHGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIIS 366
+AEP S A+ + + G+ +G GS++TV +A + + AIKI+
Sbjct: 55 AAEPRPGAGSLQHAQPPPQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILE 114
Query: 367 KFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKD 546
K + ++ RE +V+ L H ++ + ++Y + YA+NG LL IRK
Sbjct: 115 KRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKI 174
Query: 547 QHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFAR 708
DET R + ++V A++Y H +G++HRD+K EN+L++ ++I+++DFG A+
Sbjct: 175 GSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAK 228
>AC005591-1|AAC33797.1| 367|Homo sapiens PkB-like protein.
Length = 367
Score = 101 bits (243), Expect = 2e-21
Identities = 53/174 (30%), Positives = 95/174 (54%)
Frame = +1
Query: 187 SAEPTATVHSGVEAKTERKLTVLESHGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIIS 366
+AEP S A+ + + G+ +G GS++TV +A + + AIKI+
Sbjct: 47 AAEPRPGAGSLQHAQPPPQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILE 106
Query: 367 KFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKD 546
K + ++ RE +V+ L H ++ + ++Y + YA+NG LL IRK
Sbjct: 107 KRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKI 166
Query: 547 QHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFAR 708
DET R + ++V A++Y H +G++HRD+K EN+L++ ++I+++DFG A+
Sbjct: 167 GSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAK 220
>AB209835-1|BAD93072.1| 492|Homo sapiens 3-phosphoinositide
dependent protein kinase-1 variant protein.
Length = 492
Score = 101 bits (243), Expect = 2e-21
Identities = 53/174 (30%), Positives = 95/174 (54%)
Frame = +1
Query: 187 SAEPTATVHSGVEAKTERKLTVLESHGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIIS 366
+AEP S A+ + + G+ +G GS++TV +A + + AIKI+
Sbjct: 93 AAEPRPGAGSLQHAQPPPQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILE 152
Query: 367 KFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKD 546
K + ++ RE +V+ L H ++ + ++Y + YA+NG LL IRK
Sbjct: 153 KRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKI 212
Query: 547 QHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFAR 708
DET R + ++V A++Y H +G++HRD+K EN+L++ ++I+++DFG A+
Sbjct: 213 GSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAK 266
>D43636-1|BAA07744.2| 766|Homo sapiens KIAA0096 protein.
Length = 766
Score = 101 bits (242), Expect = 3e-21
Identities = 52/149 (34%), Positives = 92/149 (61%), Gaps = 3/149 (2%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y L +T+G G +A VK+A +VA+K+I K + L +E+ +K ++H N
Sbjct: 17 YDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLD-TLATGHLFQEVRCMKLVQHPN 75
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRK-DQHIDETRGRRWFKQLVEAVDYCHERG 624
++R + I+T ++Y+++E + G + D I K ++ ++E +++F Q+V A+ YCH+
Sbjct: 76 IVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHKLH 135
Query: 625 VVHRDIKCENLLM--DHGLNIKLSDFGFA 705
VVHRD+K EN++ GL +KL+DFGF+
Sbjct: 136 VVHRDLKPENVVFFEKQGL-VKLTDFGFS 163
>BC071567-1|AAH71567.1| 765|Homo sapiens SNRK protein protein.
Length = 765
Score = 101 bits (242), Expect = 3e-21
Identities = 52/149 (34%), Positives = 92/149 (61%), Gaps = 3/149 (2%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y L +T+G G +A VK+A +VA+K+I K + L +E+ +K ++H N
Sbjct: 16 YDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLD-TLATGHLFQEVRCMKLVQHPN 74
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRK-DQHIDETRGRRWFKQLVEAVDYCHERG 624
++R + I+T ++Y+++E + G + D I K ++ ++E +++F Q+V A+ YCH+
Sbjct: 75 IVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHKLH 134
Query: 625 VVHRDIKCENLLM--DHGLNIKLSDFGFA 705
VVHRD+K EN++ GL +KL+DFGF+
Sbjct: 135 VVHRDLKPENVVFFEKQGL-VKLTDFGFS 162
>AK000231-1|BAA91023.1| 244|Homo sapiens protein ( Homo sapiens
cDNA FLJ20224 fis, clone COLF5039. ).
Length = 244
Score = 101 bits (242), Expect = 3e-21
Identities = 52/149 (34%), Positives = 92/149 (61%), Gaps = 3/149 (2%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y L +T+G G +A VK+A +VA+K+I K + L +E+ +K ++H N
Sbjct: 16 YDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLD-TLATGHLFQEVRCMKLVQHPN 74
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRK-DQHIDETRGRRWFKQLVEAVDYCHERG 624
++R + I+T ++Y+++E + G + D I K ++ ++E +++F Q+V A+ YCH+
Sbjct: 75 IVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHKLH 134
Query: 625 VVHRDIKCENLLM--DHGLNIKLSDFGFA 705
VVHRD+K EN++ GL +KL+DFGF+
Sbjct: 135 VVHRDLKPENVVFFEKQGL-VKLTDFGFS 162
>AF015254-1|AAC98891.1| 347|Homo sapiens serine/threonine kinase
protein.
Length = 347
Score = 101 bits (242), Expect = 3e-21
Identities = 57/185 (30%), Positives = 97/185 (52%), Gaps = 7/185 (3%)
Frame = +1
Query: 172 VLGEMSAEPTATVHSGVEAKTERKLTVLESH----GYMLGRTIGSGSYATVKVASSDRHN 339
++ + +PTA V + +L H + +GR +G G + V +A + +
Sbjct: 41 LMSRSNVQPTAAPGQKVMENSSGTPDILTRHFTIDDFEIGRPLGKGKFGNVYLAREKKSH 100
Query: 340 CQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENG 519
VA+K++ K Q + ++ L REIE+ L H N++R R+Y+++EYA G
Sbjct: 101 FIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRG 160
Query: 520 SLLDIIRKDQHIDETRG---RRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLS 690
L ++K DE R R ++L +A+ YCH + V+HRDIK ENLL+ +K++
Sbjct: 161 MLYKELQKSCTFDEQRTATVRAVMEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIA 220
Query: 691 DFGFA 705
DFG++
Sbjct: 221 DFGWS 225
>AK222581-1|BAD96301.1| 556|Homo sapiens 3-phosphoinositide
dependent protein kinase-1 variant protein.
Length = 556
Score = 100 bits (240), Expect = 5e-21
Identities = 53/174 (30%), Positives = 94/174 (54%)
Frame = +1
Query: 187 SAEPTATVHSGVEAKTERKLTVLESHGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIIS 366
+AEP S A+ + + G+ +G GS++TV +A + + AIKI+
Sbjct: 55 AAEPRPGAGSLQHAQPPPQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILE 114
Query: 367 KFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKD 546
K + ++ RE +V+ L H ++ + ++Y + YA+NG LL IRK
Sbjct: 115 KRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKI 174
Query: 547 QHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFAR 708
DET R + ++V A +Y H +G++HRD+K EN+L++ ++I+++DFG A+
Sbjct: 175 GSFDETCTRFYTAEIVSASEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAK 228
>AJ785968-1|CAH05056.1| 396|Homo sapiens PDPK2 protein protein.
Length = 396
Score = 100 bits (240), Expect = 5e-21
Identities = 53/174 (30%), Positives = 94/174 (54%)
Frame = +1
Query: 187 SAEPTATVHSGVEAKTERKLTVLESHGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIIS 366
+AEP S A+ + + G+ +G GS++TV +A + + AIKI+
Sbjct: 28 AAEPRPGAGSLQHAQPPPQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILE 87
Query: 367 KFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKD 546
K + ++ RE +V+ L H ++ + ++Y + YA+NG LL IRK
Sbjct: 88 KRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKI 147
Query: 547 QHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFAR 708
DET R + ++V A++Y H +G++HRD+K EN+L++ + I+++DFG A+
Sbjct: 148 GSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMYIQITDFGTAK 201
>AF226044-1|AAF86944.1| 765|Homo sapiens HSNFRK protein.
Length = 765
Score = 100 bits (240), Expect = 5e-21
Identities = 52/149 (34%), Positives = 92/149 (61%), Gaps = 3/149 (2%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y L +T+G G +A VK+A +VA+K+I K + L +E+ +K ++H N
Sbjct: 16 YDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLD-TLATGHLFQEVRCMKLVQHPN 74
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRK-DQHIDETRGRRWFKQLVEAVDYCHERG 624
++R + I+T ++Y+++E + G + D I K ++ ++E +++F Q+V A+ YCH+
Sbjct: 75 IVRLYEVIDTQTKLYLILELGDEGDMFDYIMKHEEGLNEDLPKKYFAQIVHAISYCHKLH 134
Query: 625 VVHRDIKCENLLM--DHGLNIKLSDFGFA 705
VVHRD+K EN++ GL +KL+DFGF+
Sbjct: 135 VVHRDLKPENVVFFEKQGL-VKLTDFGFS 162
>BC111088-1|AAI11089.1| 252|Homo sapiens TSSK4 protein protein.
Length = 252
Score = 99.5 bits (237), Expect = 1e-20
Identities = 44/95 (46%), Positives = 65/95 (68%)
Frame = +1
Query: 424 VKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAV 603
+K L+H+ LI F +AIE+T RVYI++E A+ G +L+ I++ E +WF QL +
Sbjct: 1 MKVLRHKYLINFYRAIESTSRVYIILELAQGGDVLEWIQRYGACSEPLAGKWFSQLTLGI 60
Query: 604 DYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFAR 708
Y H + +VHRD+K ENLL+D N+K+SDFGFA+
Sbjct: 61 AYLHSKSIVHRDLKLENLLLDKWENVKISDFGFAK 95
>BC026158-1|AAH26158.1| 1315|Homo sapiens serine/threonine kinase
36, fused homolog (Drosophila) protein.
Length = 1315
Score = 98.3 bits (234), Expect = 2e-20
Identities = 56/147 (38%), Positives = 80/147 (54%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y + IG GS+ V VA+K I K L+ L REIE+++GL+H N
Sbjct: 4 YHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRN-LQREIEIMRGLRHPN 62
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
++ L + ET V +V +YAE G L I+ D + E + + QLV A+ Y H +
Sbjct: 63 IVHMLDSFETDKEVVVVTDYAE-GELFQILEDDGKLPEDQVQAIAAQLVSALYYLHSHRI 121
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFAR 708
+HRD+K +N+L+ G IKL DFGFAR
Sbjct: 122 LHRDMKPQNILLAKGGGIKLCDFGFAR 148
>AF200815-1|AAF97028.1| 1315|Homo sapiens FUSED serine/threonine
kinase protein.
Length = 1315
Score = 98.3 bits (234), Expect = 2e-20
Identities = 56/147 (38%), Positives = 80/147 (54%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y + IG GS+ V VA+K I K L+ L REIE+++GL+H N
Sbjct: 4 YHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRN-LQREIEIMRGLRHPN 62
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
++ L + ET V +V +YAE G L I+ D + E + + QLV A+ Y H +
Sbjct: 63 IVHMLDSFETDKEVVVVTDYAE-GELFQILEDDGKLPEDQVQAIAAQLVSALYYLHSHRI 121
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFAR 708
+HRD+K +N+L+ G IKL DFGFAR
Sbjct: 122 LHRDMKPQNILLAKGGGIKLCDFGFAR 148
>AB033104-1|BAA86592.1| 1311|Homo sapiens KIAA1278 protein protein.
Length = 1311
Score = 98.3 bits (234), Expect = 2e-20
Identities = 56/147 (38%), Positives = 80/147 (54%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y + IG GS+ V VA+K I K L+ L REIE+++GL+H N
Sbjct: 21 YHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRN-LQREIEIMRGLRHPN 79
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
++ L + ET V +V +YAE G L I+ D + E + + QLV A+ Y H +
Sbjct: 80 IVHMLDSFETDKEVVVVTDYAE-GELFQILEDDGKLPEDQVQAIAAQLVSALYYLHSHRI 138
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFAR 708
+HRD+K +N+L+ G IKL DFGFAR
Sbjct: 139 LHRDMKPQNILLAKGGGIKLCDFGFAR 165
>AK131534-1|BAD18671.1| 766|Homo sapiens protein ( Homo sapiens
cDNA FLJ16763 fis, clone BRAMY3018357, weakly similar
to SNF1-related protein kinase KIN10 (EC 2.7.1.-). ).
Length = 766
Score = 96.7 bits (230), Expect = 7e-20
Identities = 44/123 (35%), Positives = 76/123 (61%), Gaps = 1/123 (0%)
Frame = +1
Query: 340 CQ-VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAEN 516
CQ VAIKI+++ + L K + REI ++K ++H ++++ E +Y+V+E+
Sbjct: 88 CQKVAIKIVNREKLSESVLMK-VEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSG 146
Query: 517 GSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDF 696
G L D + K + R++F+Q++ A+D+CH + HRD+K ENLL+D NI+++DF
Sbjct: 147 GELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIRIADF 206
Query: 697 GFA 705
G A
Sbjct: 207 GMA 209
>BC017575-1|AAH17575.1| 476|Homo sapiens CHK1 checkpoint homolog
(S. pombe) protein.
Length = 476
Score = 95.5 bits (227), Expect = 2e-19
Identities = 54/144 (37%), Positives = 81/144 (56%)
Frame = +1
Query: 274 LGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLI 453
L +T+G G+Y V++A + VA+KI+ +A + + +EI + K L HEN++
Sbjct: 11 LVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVD--CPENIKKEICINKMLNHENVV 68
Query: 454 RFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVH 633
+F + Y+ +EY G L D I D + E +R+F QL+ V Y H G+ H
Sbjct: 69 KFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGITH 128
Query: 634 RDIKCENLLMDHGLNIKLSDFGFA 705
RDIK ENLL+D N+K+SDFG A
Sbjct: 129 RDIKPENLLLDERDNLKISDFGLA 152
>BC004202-1|AAH04202.1| 476|Homo sapiens CHEK1 protein protein.
Length = 476
Score = 95.5 bits (227), Expect = 2e-19
Identities = 54/144 (37%), Positives = 81/144 (56%)
Frame = +1
Query: 274 LGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLI 453
L +T+G G+Y V++A + VA+KI+ +A + + +EI + K L HEN++
Sbjct: 11 LVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVD--CPENIKKEICINKMLNHENVV 68
Query: 454 RFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVH 633
+F + Y+ +EY G L D I D + E +R+F QL+ V Y H G+ H
Sbjct: 69 KFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGITH 128
Query: 634 RDIKCENLLMDHGLNIKLSDFGFA 705
RDIK ENLL+D N+K+SDFG A
Sbjct: 129 RDIKPENLLLDERDNLKISDFGLA 152
>AF527555-1|AAM78553.1| 476|Homo sapiens CHK1 checkpoint homolog
(S. pombe) protein.
Length = 476
Score = 95.5 bits (227), Expect = 2e-19
Identities = 54/144 (37%), Positives = 81/144 (56%)
Frame = +1
Query: 274 LGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLI 453
L +T+G G+Y V++A + VA+KI+ +A + + +EI + K L HEN++
Sbjct: 11 LVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVD--CPENIKKEICINKMLNHENVV 68
Query: 454 RFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVH 633
+F + Y+ +EY G L D I D + E +R+F QL+ V Y H G+ H
Sbjct: 69 KFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGITH 128
Query: 634 RDIKCENLLMDHGLNIKLSDFGFA 705
RDIK ENLL+D N+K+SDFG A
Sbjct: 129 RDIKPENLLLDERDNLKISDFGLA 152
>AF032874-1|AAB88852.1| 476|Homo sapiens protein kinase protein.
Length = 476
Score = 95.5 bits (227), Expect = 2e-19
Identities = 54/144 (37%), Positives = 81/144 (56%)
Frame = +1
Query: 274 LGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLI 453
L +T+G G+Y V++A + VA+KI+ +A + + +EI + K L HEN++
Sbjct: 11 LVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVD--CPENIKKEICINKMLNHENVV 68
Query: 454 RFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVH 633
+F + Y+ +EY G L D I D + E +R+F QL+ V Y H G+ H
Sbjct: 69 KFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGITH 128
Query: 634 RDIKCENLLMDHGLNIKLSDFGFA 705
RDIK ENLL+D N+K+SDFG A
Sbjct: 129 RDIKPENLLLDERDNLKISDFGLA 152
>AF016582-1|AAC51736.1| 476|Homo sapiens Chk1 protein.
Length = 476
Score = 95.5 bits (227), Expect = 2e-19
Identities = 54/144 (37%), Positives = 81/144 (56%)
Frame = +1
Query: 274 LGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLI 453
L +T+G G+Y V++A + VA+KI+ +A + + +EI + K L HEN++
Sbjct: 11 LVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVD--CPENIKKEICINKMLNHENVV 68
Query: 454 RFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVH 633
+F + Y+ +EY G L D I D + E +R+F QL+ V Y H G+ H
Sbjct: 69 KFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGITH 128
Query: 634 RDIKCENLLMDHGLNIKLSDFGFA 705
RDIK ENLL+D N+K+SDFG A
Sbjct: 129 RDIKPENLLLDERDNLKISDFGLA 152
>AB032387-1|BAA84577.1| 476|Homo sapiens checkpoint kinase protein.
Length = 476
Score = 95.5 bits (227), Expect = 2e-19
Identities = 54/144 (37%), Positives = 81/144 (56%)
Frame = +1
Query: 274 LGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLI 453
L +T+G G+Y V++A + VA+KI+ +A + + +EI + K L HEN++
Sbjct: 11 LVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVD--CPENIKKEICINKMLNHENVV 68
Query: 454 RFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVH 633
+F + Y+ +EY G L D I D + E +R+F QL+ V Y H G+ H
Sbjct: 69 KFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGITH 128
Query: 634 RDIKCENLLMDHGLNIKLSDFGFA 705
RDIK ENLL+D N+K+SDFG A
Sbjct: 129 RDIKPENLLLDERDNLKISDFGLA 152
>BC041799-1|AAH41799.1| 592|Homo sapiens CDKL3 protein protein.
Length = 592
Score = 95.1 bits (226), Expect = 2e-19
Identities = 51/146 (34%), Positives = 83/146 (56%), Gaps = 1/146 (0%)
Frame = +1
Query: 274 LGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLI 453
LG+ +G GSY TV VAIKI ++ P + K REI+ +K HENL+
Sbjct: 7 LGK-VGEGSYGTVMKCKHKNTGQIVAIKIF--YERPEQSVNKIAMREIKFLKQFHHENLV 63
Query: 454 RFLQAIETTHRVYIVMEYAENGSLLDIIRKDQH-IDETRGRRWFKQLVEAVDYCHERGVV 630
++ ++++V E+ ++ ++LD ++ H ++ R R++ Q++ A+DY H ++
Sbjct: 64 NLIEVFRQKKKIHLVFEFIDH-TVLDELQHYCHGLESKRLRKYLFQILRAIDYLHSNNII 122
Query: 631 HRDIKCENLLMDHGLNIKLSDFGFAR 708
HRDIK EN+L+ KL DFGFAR
Sbjct: 123 HRDIKPENILVSQSGITKLCDFGFAR 148
>AF130372-1|AAF36509.1| 455|Homo sapiens serine-threonine protein
kinase NKIAMRE protein.
Length = 455
Score = 95.1 bits (226), Expect = 2e-19
Identities = 51/146 (34%), Positives = 83/146 (56%), Gaps = 1/146 (0%)
Frame = +1
Query: 274 LGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLI 453
LG+ +G GSY TV VAIKI ++ P + K REI+ +K HENL+
Sbjct: 7 LGK-VGEGSYGTVMKCKHKNTGQIVAIKIF--YERPEQSVNKIAMREIKFLKQFHHENLV 63
Query: 454 RFLQAIETTHRVYIVMEYAENGSLLDIIRKDQH-IDETRGRRWFKQLVEAVDYCHERGVV 630
++ ++++V E+ ++ ++LD ++ H ++ R R++ Q++ A+DY H ++
Sbjct: 64 NLIEVFRQKKKIHLVFEFIDH-TVLDELQHYCHGLESKRLRKYLFQILRAIDYLHSNNII 122
Query: 631 HRDIKCENLLMDHGLNIKLSDFGFAR 708
HRDIK EN+L+ KL DFGFAR
Sbjct: 123 HRDIKPENILVSQSGITKLCDFGFAR 148
>AB051552-1|BAB21856.1| 608|Homo sapiens KIAA1765 protein protein.
Length = 608
Score = 94.3 bits (224), Expect = 4e-19
Identities = 51/156 (32%), Positives = 82/156 (52%), Gaps = 4/156 (2%)
Frame = +1
Query: 253 LESHGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKG 432
+E H Y GR IG G++A VK A+KII K + G + + EI +++
Sbjct: 312 VEKH-YETGRVIGDGNFAVVKECRHRETRQAYAMKIIDKSRLKGK--EDMVDSEILIIQS 368
Query: 433 LKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYC 612
L H N+++ + ET +Y+++EY + G L D I + E L +A+ +
Sbjct: 369 LSHPNIVKLHEVYETDMEIYLILEYVQGGDLFDAIIESVKFPEPDAALMIMDLCKALVHM 428
Query: 613 HERGVVHRDIKCENLLM----DHGLNIKLSDFGFAR 708
H++ +VHRD+K ENLL+ D +KL+DFG A+
Sbjct: 429 HDKSIVHRDLKPENLLVQRNEDKSTTLKLADFGLAK 464
>AF045458-1|AAC32326.1| 1050|Homo sapiens serine/threonine kinase
ULK1 protein.
Length = 1050
Score = 93.9 bits (223), Expect = 5e-19
Identities = 50/151 (33%), Positives = 86/151 (56%), Gaps = 10/151 (6%)
Frame = +1
Query: 286 IGSGSYATV-KVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFL 462
IG G++A V K ++H+ +VA+K I+K + L +EI+++K LKHEN++
Sbjct: 22 IGHGAFAVVFKGRHREKHDLEVAVKCINKKNLAKS--QTLLGKEIKILKELKHENIVALY 79
Query: 463 QAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDI 642
E + VY+VMEY G L D + + + E R + +Q+ A+ H +G++HRD+
Sbjct: 80 DFQEMANSVYLVMEYCNGGDLADYLHAMRTLSEDTIRLFLQQIAGAMRLLHSKGIIHRDL 139
Query: 643 KCENLLMD---------HGLNIKLSDFGFAR 708
K +N+L+ + + +K++DFGFAR
Sbjct: 140 KPQNILLSNPAGRRANPNSIRVKIADFGFAR 170
>AB018265-1|BAA34442.2| 1066|Homo sapiens KIAA0722 protein protein.
Length = 1066
Score = 93.9 bits (223), Expect = 5e-19
Identities = 50/151 (33%), Positives = 86/151 (56%), Gaps = 10/151 (6%)
Frame = +1
Query: 286 IGSGSYATV-KVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFL 462
IG G++A V K ++H+ +VA+K I+K + L +EI+++K LKHEN++
Sbjct: 38 IGHGAFAVVFKGRHREKHDLEVAVKCINKKNLAKS--QTLLGKEIKILKELKHENIVALY 95
Query: 463 QAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDI 642
E + VY+VMEY G L D + + + E R + +Q+ A+ H +G++HRD+
Sbjct: 96 DFQEMANSVYLVMEYCNGGDLADYLHAMRTLSEDTIRLFLQQIAGAMRLLHSKGIIHRDL 155
Query: 643 KCENLLMD---------HGLNIKLSDFGFAR 708
K +N+L+ + + +K++DFGFAR
Sbjct: 156 KPQNILLSNPAGRRANPNSIRVKIADFGFAR 186
>AL834498-1|CAD39156.1| 716|Homo sapiens hypothetical protein
protein.
Length = 716
Score = 93.5 bits (222), Expect = 7e-19
Identities = 54/157 (34%), Positives = 82/157 (52%), Gaps = 4/157 (2%)
Frame = +1
Query: 247 TVLESHGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVV 426
T+LE Y +G+ IG G++A VK + A+KII K + G + + E+ ++
Sbjct: 339 TLLEK--YKIGKVIGDGNFAVVKECIDRSTGKEFALKIIDKAKCCGK--EHLIENEVSIL 394
Query: 427 KGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVD 606
+ +KH N+I ++ +ET +++VME + G L D I E G L A+
Sbjct: 395 RRVKHPNIIMLVEEMETATELFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALR 454
Query: 607 YCHERGVVHRDIKCENLLM----DHGLNIKLSDFGFA 705
Y H +VHRDIK ENLL+ D ++KL DFG A
Sbjct: 455 YLHGLSIVHRDIKPENLLVCEYPDGTKSLKLGDFGLA 491
>AL121914-5|CAI19324.1| 271|Homo sapiens aurora kinase A protein.
Length = 271
Score = 93.5 bits (222), Expect = 7e-19
Identities = 45/139 (32%), Positives = 76/139 (54%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
+ +GR +G G + V +A + +A+K++ K Q ++ L RE+E+ L+H N
Sbjct: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
++R RVY+++EYA G++ ++K DE R + +L A+ YCH + V
Sbjct: 193 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRV 252
Query: 628 VHRDIKCENLLMDHGLNIK 684
+HRDIK ENLL+ +K
Sbjct: 253 IHRDIKPENLLLGSAGELK 271
>AC093748-1|AAY40983.1| 443|Homo sapiens unknown protein.
Length = 443
Score = 93.5 bits (222), Expect = 7e-19
Identities = 54/157 (34%), Positives = 82/157 (52%), Gaps = 4/157 (2%)
Frame = +1
Query: 247 TVLESHGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVV 426
T+LE Y +G+ IG G++A VK + A+KII K + G + + E+ ++
Sbjct: 136 TLLEK--YKIGKVIGDGNFAVVKECIDRSTGKEFALKIIDKAKCCGK--EHLIENEVSIL 191
Query: 427 KGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVD 606
+ +KH N+I ++ +ET +++VME + G L D I E G L A+
Sbjct: 192 RRVKHPNIIMLVEEMETATELFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALR 251
Query: 607 YCHERGVVHRDIKCENLLM----DHGLNIKLSDFGFA 705
Y H +VHRDIK ENLL+ D ++KL DFG A
Sbjct: 252 YLHGLSIVHRDIKPENLLVCEYPDGTKSLKLGDFGLA 288
>AB209181-1|BAD92418.1| 796|Homo sapiens Hypothetical protein
DKFZp761I032 variant protein.
Length = 796
Score = 93.5 bits (222), Expect = 7e-19
Identities = 54/157 (34%), Positives = 82/157 (52%), Gaps = 4/157 (2%)
Frame = +1
Query: 247 TVLESHGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVV 426
T+LE Y +G+ IG G++A VK + A+KII K + G + + E+ ++
Sbjct: 419 TLLEK--YKIGKVIGDGNFAVVKECIDRSTGKEFALKIIDKAKCCGK--EHLIENEVSIL 474
Query: 427 KGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVD 606
+ +KH N+I ++ +ET +++VME + G L D I E G L A+
Sbjct: 475 RRVKHPNIIMLVEEMETATELFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALR 534
Query: 607 YCHERGVVHRDIKCENLLM----DHGLNIKLSDFGFA 705
Y H +VHRDIK ENLL+ D ++KL DFG A
Sbjct: 535 YLHGLSIVHRDIKPENLLVCEYPDGTKSLKLGDFGLA 571
>AL390029-2|CAI15721.1| 740|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 740
Score = 93.1 bits (221), Expect = 9e-19
Identities = 50/150 (33%), Positives = 77/150 (51%), Gaps = 4/150 (2%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y +GRTIG G++A VK + A+KII K + G + + E+ +++ +KH N
Sbjct: 390 YKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGK--EHMIQNEVSILRRVKHPN 447
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
++ ++ ++ +Y+VME + G L D I E L A+ Y H +
Sbjct: 448 IVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNI 507
Query: 628 VHRDIKCENLLM----DHGLNIKLSDFGFA 705
VHRDIK ENLL+ D ++KL DFG A
Sbjct: 508 VHRDIKPENLLVYEHQDGSKSLKLGDFGLA 537
>AL390029-1|CAI15720.1| 729|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 729
Score = 93.1 bits (221), Expect = 9e-19
Identities = 50/150 (33%), Positives = 77/150 (51%), Gaps = 4/150 (2%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y +GRTIG G++A VK + A+KII K + G + + E+ +++ +KH N
Sbjct: 390 YKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGK--EHMIQNEVSILRRVKHPN 447
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
++ ++ ++ +Y+VME + G L D I E L A+ Y H +
Sbjct: 448 IVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNI 507
Query: 628 VHRDIKCENLLM----DHGLNIKLSDFGFA 705
VHRDIK ENLL+ D ++KL DFG A
Sbjct: 508 VHRDIKPENLLVYEHQDGSKSLKLGDFGLA 537
>AL160392-2|CAH70261.1| 740|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 740
Score = 93.1 bits (221), Expect = 9e-19
Identities = 50/150 (33%), Positives = 77/150 (51%), Gaps = 4/150 (2%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y +GRTIG G++A VK + A+KII K + G + + E+ +++ +KH N
Sbjct: 390 YKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGK--EHMIQNEVSILRRVKHPN 447
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
++ ++ ++ +Y+VME + G L D I E L A+ Y H +
Sbjct: 448 IVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNI 507
Query: 628 VHRDIKCENLLM----DHGLNIKLSDFGFA 705
VHRDIK ENLL+ D ++KL DFG A
Sbjct: 508 VHRDIKPENLLVYEHQDGSKSLKLGDFGLA 537
>AL160392-1|CAH70262.1| 729|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 729
Score = 93.1 bits (221), Expect = 9e-19
Identities = 50/150 (33%), Positives = 77/150 (51%), Gaps = 4/150 (2%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y +GRTIG G++A VK + A+KII K + G + + E+ +++ +KH N
Sbjct: 390 YKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGK--EHMIQNEVSILRRVKHPN 447
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
++ ++ ++ +Y+VME + G L D I E L A+ Y H +
Sbjct: 448 IVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNI 507
Query: 628 VHRDIKCENLLM----DHGLNIKLSDFGFA 705
VHRDIK ENLL+ D ++KL DFG A
Sbjct: 508 VHRDIKPENLLVYEHQDGSKSLKLGDFGLA 537
>AL157760-4|CAH70170.1| 433|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 433
Score = 93.1 bits (221), Expect = 9e-19
Identities = 50/150 (33%), Positives = 77/150 (51%), Gaps = 4/150 (2%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y +GRTIG G++A VK + A+KII K + G + + E+ +++ +KH N
Sbjct: 83 YKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGK--EHMIQNEVSILRRVKHPN 140
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
++ ++ ++ +Y+VME + G L D I E L A+ Y H +
Sbjct: 141 IVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNI 200
Query: 628 VHRDIKCENLLM----DHGLNIKLSDFGFA 705
VHRDIK ENLL+ D ++KL DFG A
Sbjct: 201 VHRDIKPENLLVYEHQDGSKSLKLGDFGLA 230
>AL157760-2|CAH70167.1| 740|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 740
Score = 93.1 bits (221), Expect = 9e-19
Identities = 50/150 (33%), Positives = 77/150 (51%), Gaps = 4/150 (2%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y +GRTIG G++A VK + A+KII K + G + + E+ +++ +KH N
Sbjct: 390 YKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGK--EHMIQNEVSILRRVKHPN 447
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
++ ++ ++ +Y+VME + G L D I E L A+ Y H +
Sbjct: 448 IVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNI 507
Query: 628 VHRDIKCENLLM----DHGLNIKLSDFGFA 705
VHRDIK ENLL+ D ++KL DFG A
Sbjct: 508 VHRDIKPENLLVYEHQDGSKSLKLGDFGLA 537
>AL157760-1|CAH70168.1| 729|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 729
Score = 93.1 bits (221), Expect = 9e-19
Identities = 50/150 (33%), Positives = 77/150 (51%), Gaps = 4/150 (2%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y +GRTIG G++A VK + A+KII K + G + + E+ +++ +KH N
Sbjct: 390 YKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGK--EHMIQNEVSILRRVKHPN 447
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
++ ++ ++ +Y+VME + G L D I E L A+ Y H +
Sbjct: 448 IVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNI 507
Query: 628 VHRDIKCENLLM----DHGLNIKLSDFGFA 705
VHRDIK ENLL+ D ++KL DFG A
Sbjct: 508 VHRDIKPENLLVYEHQDGSKSLKLGDFGLA 537
>AL157694-2|CAH70656.1| 740|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 740
Score = 93.1 bits (221), Expect = 9e-19
Identities = 50/150 (33%), Positives = 77/150 (51%), Gaps = 4/150 (2%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y +GRTIG G++A VK + A+KII K + G + + E+ +++ +KH N
Sbjct: 390 YKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGK--EHMIQNEVSILRRVKHPN 447
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
++ ++ ++ +Y+VME + G L D I E L A+ Y H +
Sbjct: 448 IVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNI 507
Query: 628 VHRDIKCENLLM----DHGLNIKLSDFGFA 705
VHRDIK ENLL+ D ++KL DFG A
Sbjct: 508 VHRDIKPENLLVYEHQDGSKSLKLGDFGLA 537
>AL157694-1|CAH70657.1| 729|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 729
Score = 93.1 bits (221), Expect = 9e-19
Identities = 50/150 (33%), Positives = 77/150 (51%), Gaps = 4/150 (2%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y +GRTIG G++A VK + A+KII K + G + + E+ +++ +KH N
Sbjct: 390 YKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGK--EHMIQNEVSILRRVKHPN 447
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
++ ++ ++ +Y+VME + G L D I E L A+ Y H +
Sbjct: 448 IVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNI 507
Query: 628 VHRDIKCENLLM----DHGLNIKLSDFGFA 705
VHRDIK ENLL+ D ++KL DFG A
Sbjct: 508 VHRDIKPENLLVYEHQDGSKSLKLGDFGLA 537
>AB002367-1|BAA20824.2| 794|Homo sapiens KIAA0369 protein.
Length = 794
Score = 93.1 bits (221), Expect = 9e-19
Identities = 50/150 (33%), Positives = 77/150 (51%), Gaps = 4/150 (2%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y +GRTIG G++A VK + A+KII K + G + + E+ +++ +KH N
Sbjct: 455 YKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGK--EHMIQNEVSILRRVKHPN 512
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
++ ++ ++ +Y+VME + G L D I E L A+ Y H +
Sbjct: 513 IVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNI 572
Query: 628 VHRDIKCENLLM----DHGLNIKLSDFGFA 705
VHRDIK ENLL+ D ++KL DFG A
Sbjct: 573 VHRDIKPENLLVYEHQDGSKSLKLGDFGLA 602
>Z92542-3|CAI42485.1| 1030|Homo sapiens cyclin-dependent kinase-like
5 protein.
Length = 1030
Score = 91.5 bits (217), Expect = 3e-18
Identities = 49/142 (34%), Positives = 79/142 (55%), Gaps = 1/142 (0%)
Frame = +1
Query: 286 IGSGSYATV-KVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFL 462
+G G+Y V K + H VAIK K + +K+ RE+++++ LK EN++
Sbjct: 19 VGEGAYGVVLKCRHKETHEI-VAIKKF-KDSEENEEVKETTLRELKMLRTLKQENIVELK 76
Query: 463 QAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDI 642
+A ++Y+V EY E L + + + + + QL++A+ +CH+ +VHRDI
Sbjct: 77 EAFRRRGKLYLVFEYVEKNMLELLEEMPNGVPPEKVKSYIYQLIKAIHWCHKNDIVHRDI 136
Query: 643 KCENLLMDHGLNIKLSDFGFAR 708
K ENLL+ H +KL DFGFAR
Sbjct: 137 KPENLLISHNDVLKLCDFGFAR 158
>Y15057-1|CAA75342.1| 1030|Homo sapiens STK9 protein protein.
Length = 1030
Score = 91.5 bits (217), Expect = 3e-18
Identities = 49/142 (34%), Positives = 79/142 (55%), Gaps = 1/142 (0%)
Frame = +1
Query: 286 IGSGSYATV-KVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFL 462
+G G+Y V K + H VAIK K + +K+ RE+++++ LK EN++
Sbjct: 19 VGEGAYGVVLKCRHKETHEI-VAIKKF-KDSEENEEVKETTLRELKMLRTLKQENIVELK 76
Query: 463 QAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDI 642
+A ++Y+V EY E L + + + + + QL++A+ +CH+ +VHRDI
Sbjct: 77 EAFRRRGKLYLVFEYVEKNMLELLEEMPNGVPPEKVKSYIYQLIKAIHWCHKNDIVHRDI 136
Query: 643 KCENLLMDHGLNIKLSDFGFAR 708
K ENLL+ H +KL DFGFAR
Sbjct: 137 KPENLLISHNDVLKLCDFGFAR 158
>AY217744-1|AAO64440.1| 1030|Homo sapiens serine/threonine kinase 9
protein.
Length = 1030
Score = 91.5 bits (217), Expect = 3e-18
Identities = 49/142 (34%), Positives = 79/142 (55%), Gaps = 1/142 (0%)
Frame = +1
Query: 286 IGSGSYATV-KVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFL 462
+G G+Y V K + H VAIK K + +K+ RE+++++ LK EN++
Sbjct: 19 VGEGAYGVVLKCRHKETHEI-VAIKKF-KDSEENEEVKETTLRELKMLRTLKQENIVELK 76
Query: 463 QAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDI 642
+A ++Y+V EY E L + + + + + QL++A+ +CH+ +VHRDI
Sbjct: 77 EAFRRRGKLYLVFEYVEKNMLELLEEMPNGVPPEKVKSYIYQLIKAIHWCHKNDIVHRDI 136
Query: 643 KCENLLMDHGLNIKLSDFGFAR 708
K ENLL+ H +KL DFGFAR
Sbjct: 137 KPENLLISHNDVLKLCDFGFAR 158
>AL109798-1|CAI41159.1| 1030|Homo sapiens cyclin-dependent
kinase-like 5 protein.
Length = 1030
Score = 91.5 bits (217), Expect = 3e-18
Identities = 49/142 (34%), Positives = 79/142 (55%), Gaps = 1/142 (0%)
Frame = +1
Query: 286 IGSGSYATV-KVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFL 462
+G G+Y V K + H VAIK K + +K+ RE+++++ LK EN++
Sbjct: 19 VGEGAYGVVLKCRHKETHEI-VAIKKF-KDSEENEEVKETTLRELKMLRTLKQENIVELK 76
Query: 463 QAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDI 642
+A ++Y+V EY E L + + + + + QL++A+ +CH+ +VHRDI
Sbjct: 77 EAFRRRGKLYLVFEYVEKNMLELLEEMPNGVPPEKVKSYIYQLIKAIHWCHKNDIVHRDI 136
Query: 643 KCENLLMDHGLNIKLSDFGFAR 708
K ENLL+ H +KL DFGFAR
Sbjct: 137 KPENLLISHNDVLKLCDFGFAR 158
>U35146-1|AAC50918.1| 493|Homo sapiens p56 KKIAMRE protein kinase
protein.
Length = 493
Score = 91.1 bits (216), Expect = 4e-18
Identities = 50/143 (34%), Positives = 78/143 (54%), Gaps = 2/143 (1%)
Frame = +1
Query: 286 IGSGSYATVKVASSDRHNCQVAIKIISKFQAPGD--YLKKFLPREIEVVKGLKHENLIRF 459
+G GSY V + VAIK KF D +KK REI+++K L+HENL+
Sbjct: 10 VGEGSYGMVMKCRNKDTGRIVAIK---KFLESDDDKMVKKIAMREIKLLKQLRHENLVNL 66
Query: 460 LQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRD 639
L+ + R Y+V E+ ++ L D+ +D +++ Q++ + +CH ++HRD
Sbjct: 67 LEVCKKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHSHNIIHRD 126
Query: 640 IKCENLLMDHGLNIKLSDFGFAR 708
IK EN+L+ +KL DFGFAR
Sbjct: 127 IKPENILVSQSGVVKLCDFGFAR 149
>BC093981-1|AAH93981.1| 493|Homo sapiens cyclin-dependent
kinase-like 2 (CDC2-related kinase) protein.
Length = 493
Score = 91.1 bits (216), Expect = 4e-18
Identities = 50/143 (34%), Positives = 78/143 (54%), Gaps = 2/143 (1%)
Frame = +1
Query: 286 IGSGSYATVKVASSDRHNCQVAIKIISKFQAPGD--YLKKFLPREIEVVKGLKHENLIRF 459
+G GSY V + VAIK KF D +KK REI+++K L+HENL+
Sbjct: 10 VGEGSYGMVMKCRNKDTGRIVAIK---KFLESDDDKMVKKIAMREIKLLKQLRHENLVNL 66
Query: 460 LQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRD 639
L+ + R Y+V E+ ++ L D+ +D +++ Q++ + +CH ++HRD
Sbjct: 67 LEVCKKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHSHNIIHRD 126
Query: 640 IKCENLLMDHGLNIKLSDFGFAR 708
IK EN+L+ +KL DFGFAR
Sbjct: 127 IKPENILVSQSGVVKLCDFGFAR 149
>BC093646-1|AAH93646.1| 493|Homo sapiens cyclin-dependent
kinase-like 2 (CDC2-related kinase) protein.
Length = 493
Score = 91.1 bits (216), Expect = 4e-18
Identities = 50/143 (34%), Positives = 78/143 (54%), Gaps = 2/143 (1%)
Frame = +1
Query: 286 IGSGSYATVKVASSDRHNCQVAIKIISKFQAPGD--YLKKFLPREIEVVKGLKHENLIRF 459
+G GSY V + VAIK KF D +KK REI+++K L+HENL+
Sbjct: 10 VGEGSYGMVMKCRNKDTGRIVAIK---KFLESDDDKMVKKIAMREIKLLKQLRHENLVNL 66
Query: 460 LQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRD 639
L+ + R Y+V E+ ++ L D+ +D +++ Q++ + +CH ++HRD
Sbjct: 67 LEVCKKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHSHNIIHRD 126
Query: 640 IKCENLLMDHGLNIKLSDFGFAR 708
IK EN+L+ +KL DFGFAR
Sbjct: 127 IKPENILVSQSGVVKLCDFGFAR 149
>AK058166-1|BAB71697.1| 128|Homo sapiens protein ( Homo sapiens
cDNA FLJ25437 fis, clone TST08312. ).
Length = 128
Score = 91.1 bits (216), Expect = 4e-18
Identities = 42/99 (42%), Positives = 68/99 (68%), Gaps = 1/99 (1%)
Frame = +1
Query: 250 VLESHGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVK 429
+L GY LGRTIG GSY+ VKVA+S ++ VAIK++ + +AP D++ KFLPRE+ +++
Sbjct: 6 LLSELGYKLGRTIGEGSYSKVKVATSKKYKGTVAIKVVDRRRAPPDFVNKFLPRELSILR 65
Query: 430 GLKHENLIRFLQAIETTH-RVYIVMEYAENGSLLDIIRK 543
G++H +++ + IE + ++YIVME A L + R+
Sbjct: 66 GVRHPHIVHVFEFIEVCNGKLYIVMEAAATDLLQAVQRR 104
>X66358-1|CAA47002.1| 358|Homo sapiens serine/threonine protein
kinase protein.
Length = 358
Score = 89.8 bits (213), Expect = 8e-18
Identities = 50/142 (35%), Positives = 76/142 (53%), Gaps = 1/142 (0%)
Frame = +1
Query: 286 IGSGSYATV-KVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFL 462
IG GSY V K + D K + P +KK REI ++K LKH NL+ L
Sbjct: 11 IGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDP--VIKKIALREIRMLKQLKHPNLVNLL 68
Query: 463 QAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDI 642
+ R+++V EY ++ L ++ R + + E + Q ++AV++CH+ +HRD+
Sbjct: 69 EVFRRKRRLHLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQTLQAVNFCHKHNCIHRDV 128
Query: 643 KCENLLMDHGLNIKLSDFGFAR 708
K EN+L+ IKL DFGFAR
Sbjct: 129 KPENILITKHSVIKLCDFGFAR 150
>U56998-1|AAC50637.1| 607|Homo sapiens putative serine/threonine
protein kinase PRK protein.
Length = 607
Score = 89.8 bits (213), Expect = 8e-18
Identities = 41/146 (28%), Positives = 76/146 (52%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y+ GR +G G +A A+ A+K+I + + + ++ + EIE+ + L+H +
Sbjct: 23 YLKGRLLGKGGFARCYEATDTETGSAYAVKVIPQSRVAKPHQREKILNEIELHRDLQHRH 82
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
++RF E +YI +E SL I + + E R + +Q++ + Y H+RG+
Sbjct: 83 IVRFSHHFEDADNIYIFLELCSRKSLAHIWKARHTLLEPEVRYYLRQILSGLKYLHQRGI 142
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFA 705
+HRD+K N + + +K+ DFG A
Sbjct: 143 LHRDLKLGNFFITENMELKVGDFGLA 168
>BC127622-1|AAI27623.1| 596|Homo sapiens myosin light chain kinase
2, skeletal muscle protein.
Length = 596
Score = 89.8 bits (213), Expect = 8e-18
Identities = 58/182 (31%), Positives = 89/182 (48%), Gaps = 3/182 (1%)
Frame = +1
Query: 172 VLGEMSAEPTATVHSGVEAKTERKLTVLESHGYMLGRTIGSGSYATVKVASSDRHNCQVA 351
+L + P H VE +T V +G G + V ++A
Sbjct: 256 ILDDCPPPPAPFPHRMVELRTGN---VSSEFSMNSKEALGGGKFGAVCTCMEKATGLKLA 312
Query: 352 IKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLD 531
K+I K Q P D K+ + EIEV+ L H NLI+ AIET H + + MEY E G L +
Sbjct: 313 AKVIKK-QTPKD--KEMVLLEIEVMNQLNHRNLIQLYAAIETPHEIVLFMEYIEGGELFE 369
Query: 532 -IIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDH--GLNIKLSDFGF 702
I+ +D H+ E + +Q+ + + + H+ V+H D+K EN+L + G +K+ DFG
Sbjct: 370 RIVDEDYHLTEVDTMVFVRQICDGILFMHKMRVLHLDLKPENILCVNTTGHLVKIIDFGL 429
Query: 703 AR 708
AR
Sbjct: 430 AR 431
>BC104977-1|AAI04978.1| 358|Homo sapiens cyclin-dependent
kinase-like 1 (CDC2-related kinase) protein.
Length = 358
Score = 89.8 bits (213), Expect = 8e-18
Identities = 50/142 (35%), Positives = 76/142 (53%), Gaps = 1/142 (0%)
Frame = +1
Query: 286 IGSGSYATV-KVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFL 462
IG GSY V K + D K + P +KK REI ++K LKH NL+ L
Sbjct: 11 IGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDP--VIKKIALREIRMLKQLKHPNLVNLL 68
Query: 463 QAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDI 642
+ R+++V EY ++ L ++ R + + E + Q ++AV++CH+ +HRD+
Sbjct: 69 EVFRRKRRLHLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQTLQAVNFCHKHNCIHRDV 128
Query: 643 KCENLLMDHGLNIKLSDFGFAR 708
K EN+L+ IKL DFGFAR
Sbjct: 129 KPENILITKHSVIKLCDFGFAR 150
>BC092413-1|AAH92413.1| 596|Homo sapiens myosin light chain kinase
2, skeletal muscle protein.
Length = 596
Score = 89.8 bits (213), Expect = 8e-18
Identities = 58/182 (31%), Positives = 89/182 (48%), Gaps = 3/182 (1%)
Frame = +1
Query: 172 VLGEMSAEPTATVHSGVEAKTERKLTVLESHGYMLGRTIGSGSYATVKVASSDRHNCQVA 351
+L + P H VE +T V +G G + V ++A
Sbjct: 256 ILDDCPPPPAPFPHRMVELRTGN---VSSEFSMNSKEALGGGKFGAVCTCMEKATGLKLA 312
Query: 352 IKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLD 531
K+I K Q P D K+ + EIEV+ L H NLI+ AIET H + + MEY E G L +
Sbjct: 313 AKVIKK-QTPKD--KEMVLLEIEVMNQLNHRNLIQLYAAIETPHEIVLFMEYIEGGELFE 369
Query: 532 -IIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDH--GLNIKLSDFGF 702
I+ +D H+ E + +Q+ + + + H+ V+H D+K EN+L + G +K+ DFG
Sbjct: 370 RIVDEDYHLTEVDTMVFVRQICDGILFMHKMRVLHLDLKPENILCVNTTGHLVKIIDFGL 429
Query: 703 AR 708
AR
Sbjct: 430 AR 431
>BC069627-1|AAH69627.1| 596|Homo sapiens skeletal myosin light
chain kinase protein.
Length = 596
Score = 89.8 bits (213), Expect = 8e-18
Identities = 58/182 (31%), Positives = 89/182 (48%), Gaps = 3/182 (1%)
Frame = +1
Query: 172 VLGEMSAEPTATVHSGVEAKTERKLTVLESHGYMLGRTIGSGSYATVKVASSDRHNCQVA 351
+L + P H VE +T V +G G + V ++A
Sbjct: 256 ILDDCPPPPAPFPHRMVELRTGN---VSSEFSMNSKEALGGGKFGAVCTCMEKATGLKLA 312
Query: 352 IKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLD 531
K+I K Q P D K+ + EIEV+ L H NLI+ AIET H + + MEY E G L +
Sbjct: 313 AKVIKK-QTPKD--KEMVLLEIEVMNQLNHRNLIQLYAAIETPHEIVLFMEYIEGGELFE 369
Query: 532 -IIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDH--GLNIKLSDFGF 702
I+ +D H+ E + +Q+ + + + H+ V+H D+K EN+L + G +K+ DFG
Sbjct: 370 RIVDEDYHLTEVDTMVFVRQICDGILFMHKMRVLHLDLKPENILCVNTTGHLVKIIDFGL 429
Query: 703 AR 708
AR
Sbjct: 430 AR 431
>BC013899-1|AAH13899.1| 646|Homo sapiens polo-like kinase 3
(Drosophila) protein.
Length = 646
Score = 89.8 bits (213), Expect = 8e-18
Identities = 41/146 (28%), Positives = 76/146 (52%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y+ GR +G G +A A+ A+K+I + + + ++ + EIE+ + L+H +
Sbjct: 62 YLKGRLLGKGGFARCYEATDTETGSAYAVKVIPQSRVAKPHQREKILNEIELHRDLQHRH 121
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
++RF E +YI +E SL I + + E R + +Q++ + Y H+RG+
Sbjct: 122 IVRFSHHFEDADNIYIFLELCSRKSLAHIWKARHTLLEPEVRYYLRQILSGLKYLHQRGI 181
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFA 705
+HRD+K N + + +K+ DFG A
Sbjct: 182 LHRDLKLGNFFITENMELKVGDFGLA 207
>AY764184-1|AAU88146.1| 646|Homo sapiens polo-like kinase 3
(Drosophila) protein.
Length = 646
Score = 89.8 bits (213), Expect = 8e-18
Identities = 41/146 (28%), Positives = 76/146 (52%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y+ GR +G G +A A+ A+K+I + + + ++ + EIE+ + L+H +
Sbjct: 62 YLKGRLLGKGGFARCYEATDTETGSAYAVKVIPQSRVAKPHQREKILNEIELHRDLQHRH 121
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
++RF E +YI +E SL I + + E R + +Q++ + Y H+RG+
Sbjct: 122 IVRFSHHFEDADNIYIFLELCSRKSLAHIWKARHTLLEPEVRYYLRQILSGLKYLHQRGI 181
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFA 705
+HRD+K N + + +K+ DFG A
Sbjct: 182 LHRDLKLGNFFITENMELKVGDFGLA 207
>AY525548-1|AAS00095.1| 358|Homo sapiens cyclin-dependent
kinase-like 1 (CDC2-related kinase) protein.
Length = 358
Score = 89.8 bits (213), Expect = 8e-18
Identities = 50/142 (35%), Positives = 76/142 (53%), Gaps = 1/142 (0%)
Frame = +1
Query: 286 IGSGSYATV-KVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFL 462
IG GSY V K + D K + P +KK REI ++K LKH NL+ L
Sbjct: 11 IGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDP--VIKKIALREIRMLKQLKHPNLVNLL 68
Query: 463 QAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDI 642
+ R+++V EY ++ L ++ R + + E + Q ++AV++CH+ +HRD+
Sbjct: 69 EVFRRKRRLHLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQTLQAVNFCHKHNCIHRDV 128
Query: 643 KCENLLMDHGLNIKLSDFGFAR 708
K EN+L+ IKL DFGFAR
Sbjct: 129 KPENILITKHSVIKLCDFGFAR 150
>AL592166-11|CAI13006.1| 646|Homo sapiens polo-like kinase 3
(Drosophila) protein.
Length = 646
Score = 89.8 bits (213), Expect = 8e-18
Identities = 41/146 (28%), Positives = 76/146 (52%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y+ GR +G G +A A+ A+K+I + + + ++ + EIE+ + L+H +
Sbjct: 62 YLKGRLLGKGGFARCYEATDTETGSAYAVKVIPQSRVAKPHQREKILNEIELHRDLQHRH 121
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
++RF E +YI +E SL I + + E R + +Q++ + Y H+RG+
Sbjct: 122 IVRFSHHFEDADNIYIFLELCSRKSLAHIWKARHTLLEPEVRYYLRQILSGLKYLHQRGI 181
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFA 705
+HRD+K N + + +K+ DFG A
Sbjct: 182 LHRDLKLGNFFITENMELKVGDFGLA 207
>AL160175-10|CAC10006.1| 596|Homo sapiens myosin light chain kinase
2, skeletal muscle protein.
Length = 596
Score = 89.8 bits (213), Expect = 8e-18
Identities = 58/182 (31%), Positives = 89/182 (48%), Gaps = 3/182 (1%)
Frame = +1
Query: 172 VLGEMSAEPTATVHSGVEAKTERKLTVLESHGYMLGRTIGSGSYATVKVASSDRHNCQVA 351
+L + P H VE +T V +G G + V ++A
Sbjct: 256 ILDDCPPPPAPFPHRMVELRTGN---VSSEFSMNSKEALGGGKFGAVCTCMEKATGLKLA 312
Query: 352 IKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLD 531
K+I K Q P D K+ + EIEV+ L H NLI+ AIET H + + MEY E G L +
Sbjct: 313 AKVIKK-QTPKD--KEMVLLEIEVMNQLNHRNLIQLYAAIETPHEIVLFMEYIEGGELFE 369
Query: 532 -IIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDH--GLNIKLSDFGF 702
I+ +D H+ E + +Q+ + + + H+ V+H D+K EN+L + G +K+ DFG
Sbjct: 370 RIVDEDYHLTEVDTMVFVRQICDGILFMHKMRVLHLDLKPENILCVNTTGHLVKIIDFGL 429
Query: 703 AR 708
AR
Sbjct: 430 AR 431
>AJ272502-1|CAC81354.1| 596|Homo sapiens skeletal muscle-specific
myosin light chain kinase protein.
Length = 596
Score = 89.8 bits (213), Expect = 8e-18
Identities = 58/182 (31%), Positives = 89/182 (48%), Gaps = 3/182 (1%)
Frame = +1
Query: 172 VLGEMSAEPTATVHSGVEAKTERKLTVLESHGYMLGRTIGSGSYATVKVASSDRHNCQVA 351
+L + P H VE +T V +G G + V ++A
Sbjct: 256 ILDDCPPPPAPFPHRMVELRTGN---VSSEFSMNSKEALGGGKFGAVCTCMEKATGLKLA 312
Query: 352 IKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLD 531
K+I K Q P D K+ + EIEV+ L H NLI+ AIET H + + MEY E G L +
Sbjct: 313 AKVIKK-QTPKD--KEMVLLEIEVMNQLNHRNLIQLYAAIETPHEIVLFMEYIEGGELFE 369
Query: 532 -IIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDH--GLNIKLSDFGF 702
I+ +D H+ E + +Q+ + + + H+ V+H D+K EN+L + G +K+ DFG
Sbjct: 370 RIVDEDYHLTEVDTMVFVRQICDGILFMHKMRVLHLDLKPENILCVNTTGHLVKIIDFGL 429
Query: 703 AR 708
AR
Sbjct: 430 AR 431
>AF325549-1|AAK15494.1| 596|Homo sapiens skeletal myosin light
chain kinase protein.
Length = 596
Score = 89.8 bits (213), Expect = 8e-18
Identities = 58/182 (31%), Positives = 89/182 (48%), Gaps = 3/182 (1%)
Frame = +1
Query: 172 VLGEMSAEPTATVHSGVEAKTERKLTVLESHGYMLGRTIGSGSYATVKVASSDRHNCQVA 351
+L + P H VE +T V +G G + V ++A
Sbjct: 256 ILDDCPPPPAPFPHRMVELRTGN---VSSEFSMNSKEALGGGKFGAVCTCMEKATGLKLA 312
Query: 352 IKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLD 531
K+I K Q P D K+ + EIEV+ L H NLI+ AIET H + + MEY E G L +
Sbjct: 313 AKVIKK-QTPKD--KEMVLLEIEVMNQLNHRNLIQLYAAIETPHEIVLFMEYIEGGELFE 369
Query: 532 -IIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDH--GLNIKLSDFGF 702
I+ +D H+ E + +Q+ + + + H+ V+H D+K EN+L + G +K+ DFG
Sbjct: 370 RIVDEDYHLTEVDTMVFVRQICDGILFMHKMRVLHLDLKPENILCVNTTGHLVKIIDFGL 429
Query: 703 AR 708
AR
Sbjct: 430 AR 431
>AB209875-1|BAD93112.1| 621|Homo sapiens polo-like kinase 3 variant
protein.
Length = 621
Score = 89.8 bits (213), Expect = 8e-18
Identities = 41/146 (28%), Positives = 76/146 (52%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y+ GR +G G +A A+ A+K+I + + + ++ + EIE+ + L+H +
Sbjct: 37 YLKGRLLGKGGFARCYEATDTETGSAYAVKVIPQSRVAKPHQREKILNEIELHRDLQHRH 96
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
++RF E +YI +E SL I + + E R + +Q++ + Y H+RG+
Sbjct: 97 IVRFSHHFEDADNIYIFLELCSRKSLAHIWKARHTLLEPEVRYYLRQILSGLKYLHQRGI 156
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFA 705
+HRD+K N + + +K+ DFG A
Sbjct: 157 LHRDLKLGNFFITENMELKVGDFGLA 182
>AJ293866-1|CAC10659.1| 646|Homo sapiens FNK serine/threonine
protein kinase protein.
Length = 646
Score = 89.4 bits (212), Expect = 1e-17
Identities = 41/146 (28%), Positives = 76/146 (52%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y+ GR +G G +A A+ A+K+I + + + ++ + EIE+ + L+H +
Sbjct: 62 YLKGRLLGKGGFARCYEATDTETGSAYAVKVIPQSRVVKPHQREKILNEIELHRDLQHRH 121
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
++RF E +YI +E SL I + + E R + +Q++ + Y H+RG+
Sbjct: 122 IVRFSHHFEDADNIYIFLELCSRKSLAHIWKARHTLLEPEVRYYLRQILSGLKYLHQRGI 181
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFA 705
+HRD+K N + + +K+ DFG A
Sbjct: 182 LHRDLKLGNFFITENMELKVGDFGLA 207
>U24153-1|AAA65442.1| 525|Homo sapiens p21-activated protein kinase
protein.
Length = 525
Score = 89.0 bits (211), Expect = 1e-17
Identities = 48/139 (34%), Positives = 82/139 (58%)
Frame = +1
Query: 286 IGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQ 465
IG G+ TV A+ +VAIK I+ + P K+ + EI V+K LK+ N++ FL
Sbjct: 255 IGQGASGTVFTATDVALGQEVAIKQINLQKQPK---KELIINEILVMKELKNPNIVNFLD 311
Query: 466 AIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIK 645
+ +++VMEY GSL D++ + +DE + ++ ++A+++ H V+HRDIK
Sbjct: 312 SYLVGDELFVVMEYLAGGSLTDVVTETACMDEAQIAAVCRECLQALEFLHANQVIHRDIK 371
Query: 646 CENLLMDHGLNIKLSDFGF 702
+N+L+ ++KL+DFGF
Sbjct: 372 SDNVLLGMEGSVKLTDFGF 390
>BC056423-1|AAH56423.1| 214|Homo sapiens ULK3 protein protein.
Length = 214
Score = 89.0 bits (211), Expect = 1e-17
Identities = 50/154 (32%), Positives = 89/154 (57%), Gaps = 3/154 (1%)
Frame = +1
Query: 265 GYMLGRTIGSGSYATVKVASSDRHNCQV-AIKIISKFQAPGDYLKKFLPREIEVVKGLKH 441
G++L +GSG+YATV A + + +V AIK ++K ++ L EIE++KG++H
Sbjct: 13 GFILTERLGSGTYATVYKAYAKKDTREVVAIKCVAKKSLNKASVENLLT-EIEILKGIRH 71
Query: 442 ENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHER 621
++++ + +Y++ME+ G L I + + E R + +QL A+ + HER
Sbjct: 72 PHIVQLKDFQWDSDNIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQQLASALQFLHER 131
Query: 622 GVVHRDIKCENLLMD--HGLNIKLSDFGFARGHM 717
+ H D+K +N+L+ ++KL+DFGFA+ HM
Sbjct: 132 NISHLDLKPQNILLSSLEKPHLKLADFGFAQ-HM 164
>BC036117-1|AAH36117.1| 214|Homo sapiens ULK3 protein protein.
Length = 214
Score = 89.0 bits (211), Expect = 1e-17
Identities = 50/154 (32%), Positives = 89/154 (57%), Gaps = 3/154 (1%)
Frame = +1
Query: 265 GYMLGRTIGSGSYATVKVASSDRHNCQV-AIKIISKFQAPGDYLKKFLPREIEVVKGLKH 441
G++L +GSG+YATV A + + +V AIK ++K ++ L EIE++KG++H
Sbjct: 13 GFILTERLGSGTYATVYKAYAKKDTREVVAIKCVAKKSLNKASVENLLT-EIEILKGIRH 71
Query: 442 ENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHER 621
++++ + +Y++ME+ G L I + + E R + +QL A+ + HER
Sbjct: 72 PHIVQLKDFQWDSDNIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQQLASALQFLHER 131
Query: 622 GVVHRDIKCENLLMD--HGLNIKLSDFGFARGHM 717
+ H D+K +N+L+ ++KL+DFGFA+ HM
Sbjct: 132 NISHLDLKPQNILLSSLEKPHLKLADFGFAQ-HM 164
>AB183427-1|BAF73615.1| 619|Homo sapiens maternal embryonic leucine
zipper kinase v2 protein.
Length = 619
Score = 89.0 bits (211), Expect = 1e-17
Identities = 42/102 (41%), Positives = 61/102 (59%), Gaps = 3/102 (2%)
Frame = +1
Query: 403 LPR---EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGR 573
LPR EIE +K L+H+++ + +ET +++++V+EY G L D I + E R
Sbjct: 19 LPRIKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETR 78
Query: 574 RWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFG 699
F+Q+V AV Y H +G HRD+K ENLL D +KL DFG
Sbjct: 79 VVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFG 120
>CR456418-1|CAG30304.1| 586|Homo sapiens CHEK2 protein.
Length = 586
Score = 88.6 bits (210), Expect = 2e-17
Identities = 55/156 (35%), Positives = 90/156 (57%), Gaps = 9/156 (5%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQ-VAIKIISKFQAPGDYLKKFLPR-----EIEVVK 429
Y++ +T+GSG+ VK+A +R C+ VAIKIISK + ++ P EIE++K
Sbjct: 263 YIMSKTLGSGACGEVKLAF-ERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEILK 321
Query: 430 GLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDY 609
L H +I+ + YIV+E E G L D + ++ + E + +F Q++ AV Y
Sbjct: 322 KLNHPCIIKIKNFFDAED-YYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLLAVQY 380
Query: 610 CHERGVVHRDIKCENLLM---DHGLNIKLSDFGFAR 708
HE G++HRD+K EN+L+ + IK++DFG ++
Sbjct: 381 LHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSK 416
>BC004207-1|AAH04207.1| 543|Homo sapiens CHK2 checkpoint homolog
(S. pombe) protein.
Length = 543
Score = 88.6 bits (210), Expect = 2e-17
Identities = 55/156 (35%), Positives = 90/156 (57%), Gaps = 9/156 (5%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQ-VAIKIISKFQAPGDYLKKFLPR-----EIEVVK 429
Y++ +T+GSG+ VK+A +R C+ VAIKIISK + ++ P EIE++K
Sbjct: 220 YIMSKTLGSGACGEVKLAF-ERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEILK 278
Query: 430 GLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDY 609
L H +I+ + YIV+E E G L D + ++ + E + +F Q++ AV Y
Sbjct: 279 KLNHPCIIKIKNFFDAED-YYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLLAVQY 337
Query: 610 CHERGVVHRDIKCENLLM---DHGLNIKLSDFGFAR 708
HE G++HRD+K EN+L+ + IK++DFG ++
Sbjct: 338 LHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSK 373
>AY800241-1|AAV41895.1| 543|Homo sapiens CHK2 checkpoint homolog
(S. pombe) protein.
Length = 543
Score = 88.6 bits (210), Expect = 2e-17
Identities = 55/156 (35%), Positives = 90/156 (57%), Gaps = 9/156 (5%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQ-VAIKIISKFQAPGDYLKKFLPR-----EIEVVK 429
Y++ +T+GSG+ VK+A +R C+ VAIKIISK + ++ P EIE++K
Sbjct: 220 YIMSKTLGSGACGEVKLAF-ERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEILK 278
Query: 430 GLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDY 609
L H +I+ + YIV+E E G L D + ++ + E + +F Q++ AV Y
Sbjct: 279 KLNHPCIIKIKNFFDAED-YYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLLAVQY 337
Query: 610 CHERGVVHRDIKCENLLM---DHGLNIKLSDFGFAR 708
HE G++HRD+K EN+L+ + IK++DFG ++
Sbjct: 338 LHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSK 373
>AY574904-1|AAT81413.1| 510|Homo sapiens regulated in COPD kinase
transcript variant 4 protein.
Length = 510
Score = 88.6 bits (210), Expect = 2e-17
Identities = 62/193 (32%), Positives = 96/193 (49%), Gaps = 5/193 (2%)
Frame = +1
Query: 145 GPDVRTHDNVLGEMSAEPTATVHSGVEAKTERKLTVLESHGYMLGRTIGSGSYATVKVAS 324
G ++ H + L E + + + +E L E + G +G G+Y TV
Sbjct: 202 GRSIKRHSSGLRIYDREEKFLISNEKKIFSENSLKSEEPILWTKGEILGKGAYGTVYCGL 261
Query: 325 SDRHNC----QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVY 492
+ + QVA+ +K A +Y K L E++++K LKH N++ +L + V
Sbjct: 262 TSQGQLIAVKQVALDTSNKLAAEKEYRK--LQEEVDLLKALKHVNIVAYLGTCLQENTVS 319
Query: 493 IVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCEN-LLMDH 669
I ME+ GS+ II + + E ++ KQ+++ V Y HE VVHRDIK N +LM
Sbjct: 320 IFMEFVPGGSISSIINRFGPLPEMVFCKYTKQILQGVAYLHENCVVHRDIKGNNVMLMPT 379
Query: 670 GLNIKLSDFGFAR 708
G+ IKL DFG AR
Sbjct: 380 GI-IKLIDFGCAR 391
>AY551303-1|AAS58464.1| 452|Homo sapiens protein kinase Chk2
transcript variant del2-3 protein.
Length = 452
Score = 88.6 bits (210), Expect = 2e-17
Identities = 55/156 (35%), Positives = 90/156 (57%), Gaps = 9/156 (5%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQ-VAIKIISKFQAPGDYLKKFLPR-----EIEVVK 429
Y++ +T+GSG+ VK+A +R C+ VAIKIISK + ++ P EIE++K
Sbjct: 129 YIMSKTLGSGACGEVKLAF-ERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEILK 187
Query: 430 GLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDY 609
L H +I+ + YIV+E E G L D + ++ + E + +F Q++ AV Y
Sbjct: 188 KLNHPCIIKIKNFFDAED-YYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLLAVQY 246
Query: 610 CHERGVVHRDIKCENLLM---DHGLNIKLSDFGFAR 708
HE G++HRD+K EN+L+ + IK++DFG ++
Sbjct: 247 LHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSK 282
>AY551297-1|AAS58458.1| 586|Homo sapiens protein kinase Chk2
transcript variant insX protein.
Length = 586
Score = 88.6 bits (210), Expect = 2e-17
Identities = 55/156 (35%), Positives = 90/156 (57%), Gaps = 9/156 (5%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQ-VAIKIISKFQAPGDYLKKFLPR-----EIEVVK 429
Y++ +T+GSG+ VK+A +R C+ VAIKIISK + ++ P EIE++K
Sbjct: 263 YIMSKTLGSGACGEVKLAF-ERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEILK 321
Query: 430 GLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDY 609
L H +I+ + YIV+E E G L D + ++ + E + +F Q++ AV Y
Sbjct: 322 KLNHPCIIKIKNFFDAED-YYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLLAVQY 380
Query: 610 CHERGVVHRDIKCENLLM---DHGLNIKLSDFGFAR 708
HE G++HRD+K EN+L+ + IK++DFG ++
Sbjct: 381 LHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSK 416
>AL121825-1|CAH73823.1| 543|Homo sapiens CHK2 checkpoint homolog
(S. pombe) protein.
Length = 543
Score = 88.6 bits (210), Expect = 2e-17
Identities = 55/156 (35%), Positives = 90/156 (57%), Gaps = 9/156 (5%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQ-VAIKIISKFQAPGDYLKKFLPR-----EIEVVK 429
Y++ +T+GSG+ VK+A +R C+ VAIKIISK + ++ P EIE++K
Sbjct: 220 YIMSKTLGSGACGEVKLAF-ERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEILK 278
Query: 430 GLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDY 609
L H +I+ + YIV+E E G L D + ++ + E + +F Q++ AV Y
Sbjct: 279 KLNHPCIIKIKNFFDAED-YYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLLAVQY 337
Query: 610 CHERGVVHRDIKCENLLM---DHGLNIKLSDFGFAR 708
HE G++HRD+K EN+L+ + IK++DFG ++
Sbjct: 338 LHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSK 373
>AL117330-1|CAH73875.1| 543|Homo sapiens CHK2 checkpoint homolog
(S. pombe) protein.
Length = 543
Score = 88.6 bits (210), Expect = 2e-17
Identities = 55/156 (35%), Positives = 90/156 (57%), Gaps = 9/156 (5%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQ-VAIKIISKFQAPGDYLKKFLPR-----EIEVVK 429
Y++ +T+GSG+ VK+A +R C+ VAIKIISK + ++ P EIE++K
Sbjct: 220 YIMSKTLGSGACGEVKLAF-ERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEILK 278
Query: 430 GLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDY 609
L H +I+ + YIV+E E G L D + ++ + E + +F Q++ AV Y
Sbjct: 279 KLNHPCIIKIKNFFDAED-YYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLLAVQY 337
Query: 610 CHERGVVHRDIKCENLLM---DHGLNIKLSDFGFAR 708
HE G++HRD+K EN+L+ + IK++DFG ++
Sbjct: 338 LHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSK 373
>AJ131197-1|CAA10319.1| 543|Homo sapiens protein kinase protein.
Length = 543
Score = 88.6 bits (210), Expect = 2e-17
Identities = 55/156 (35%), Positives = 90/156 (57%), Gaps = 9/156 (5%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQ-VAIKIISKFQAPGDYLKKFLPR-----EIEVVK 429
Y++ +T+GSG+ VK+A +R C+ VAIKIISK + ++ P EIE++K
Sbjct: 220 YIMSKTLGSGACGEVKLAF-ERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEILK 278
Query: 430 GLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDY 609
L H +I+ + YIV+E E G L D + ++ + E + +F Q++ AV Y
Sbjct: 279 KLNHPCIIKIKNFFDAED-YYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLLAVQY 337
Query: 610 CHERGVVHRDIKCENLLM---DHGLNIKLSDFGFAR 708
HE G++HRD+K EN+L+ + IK++DFG ++
Sbjct: 338 LHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSK 373
>AF174135-1|AAD48504.1| 543|Homo sapiens protein kinase CHK2
protein.
Length = 543
Score = 88.6 bits (210), Expect = 2e-17
Identities = 55/156 (35%), Positives = 90/156 (57%), Gaps = 9/156 (5%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQ-VAIKIISKFQAPGDYLKKFLPR-----EIEVVK 429
Y++ +T+GSG+ VK+A +R C+ VAIKIISK + ++ P EIE++K
Sbjct: 220 YIMSKTLGSGACGEVKLAF-ERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEILK 278
Query: 430 GLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDY 609
L H +I+ + YIV+E E G L D + ++ + E + +F Q++ AV Y
Sbjct: 279 KLNHPCIIKIKNFFDAED-YYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLLAVQY 337
Query: 610 CHERGVVHRDIKCENLLM---DHGLNIKLSDFGFAR 708
HE G++HRD+K EN+L+ + IK++DFG ++
Sbjct: 338 LHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSK 373
>AF096279-1|AAD11784.1| 543|Homo sapiens HuCds1 kinase protein.
Length = 543
Score = 88.6 bits (210), Expect = 2e-17
Identities = 55/156 (35%), Positives = 90/156 (57%), Gaps = 9/156 (5%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQ-VAIKIISKFQAPGDYLKKFLPR-----EIEVVK 429
Y++ +T+GSG+ VK+A +R C+ VAIKIISK + ++ P EIE++K
Sbjct: 220 YIMSKTLGSGACGEVKLAF-ERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEILK 278
Query: 430 GLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDY 609
L H +I+ + YIV+E E G L D + ++ + E + +F Q++ AV Y
Sbjct: 279 KLNHPCIIKIKNFFDAED-YYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLLAVQY 337
Query: 610 CHERGVVHRDIKCENLLM---DHGLNIKLSDFGFAR 708
HE G++HRD+K EN+L+ + IK++DFG ++
Sbjct: 338 LHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSK 373
>AF086904-1|AAC83693.1| 543|Homo sapiens protein kinase Chk2
protein.
Length = 543
Score = 88.6 bits (210), Expect = 2e-17
Identities = 55/156 (35%), Positives = 90/156 (57%), Gaps = 9/156 (5%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQ-VAIKIISKFQAPGDYLKKFLPR-----EIEVVK 429
Y++ +T+GSG+ VK+A +R C+ VAIKIISK + ++ P EIE++K
Sbjct: 220 YIMSKTLGSGACGEVKLAF-ERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEILK 278
Query: 430 GLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDY 609
L H +I+ + YIV+E E G L D + ++ + E + +F Q++ AV Y
Sbjct: 279 KLNHPCIIKIKNFFDAED-YYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLLAVQY 337
Query: 610 CHERGVVHRDIKCENLLM---DHGLNIKLSDFGFAR 708
HE G++HRD+K EN+L+ + IK++DFG ++
Sbjct: 338 LHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSK 373
>AB058714-1|BAB47440.1| 715|Homo sapiens KIAA1811 protein protein.
Length = 715
Score = 88.2 bits (209), Expect = 3e-17
Identities = 36/99 (36%), Positives = 62/99 (62%)
Frame = +1
Query: 409 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQ 588
REI ++K ++H ++++ E +Y+V+E+ G L D + K + R++F+Q
Sbjct: 17 REIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQ 76
Query: 589 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 705
+V A+D+CH + HRD+K ENLL+D NI+++DFG A
Sbjct: 77 IVSALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGMA 115
>AB006972-1|BAB69958.1| 970|Homo sapiens Sak protein.
Length = 970
Score = 88.2 bits (209), Expect = 3e-17
Identities = 44/147 (29%), Positives = 79/147 (53%), Gaps = 1/147 (0%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
+ +G +G GS+A V A S +VAIK+I K + + + E+++ LKH +
Sbjct: 12 FKVGNLLGKGSFAGVYRAESIHSGLEVAIKMIDKKAMYKAGMVQRVQNEVKIHCQLKHPS 71
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIR-KDQHIDETRGRRWFKQLVEAVDYCHERG 624
++ E ++ VY+V+E NG + ++ + + E R + Q++ + Y H G
Sbjct: 72 ILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLHSHG 131
Query: 625 VVHRDIKCENLLMDHGLNIKLSDFGFA 705
++HRD+ NLL+ +NIK++DFG A
Sbjct: 132 ILHRDLTLSNLLLTRNMNIKIADFGLA 158
>Y13115-1|CAA73575.1| 970|Homo sapiens serine/threonine protein
kinase protein.
Length = 970
Score = 87.8 bits (208), Expect = 3e-17
Identities = 44/147 (29%), Positives = 79/147 (53%), Gaps = 1/147 (0%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
+ +G +G GS+A V A S +VAIK+I K + + + E+++ LKH +
Sbjct: 12 FKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVKNEVKIHCQLKHPS 71
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIR-KDQHIDETRGRRWFKQLVEAVDYCHERG 624
++ E ++ VY+V+E NG + ++ + + E R + Q++ + Y H G
Sbjct: 72 ILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLHSHG 131
Query: 625 VVHRDIKCENLLMDHGLNIKLSDFGFA 705
++HRD+ NLL+ +NIK++DFG A
Sbjct: 132 ILHRDLTLSNLLLTRNMNIKIADFGLA 158
>BC036023-1|AAH36023.1| 970|Homo sapiens polo-like kinase 4
(Drosophila) protein.
Length = 970
Score = 87.8 bits (208), Expect = 3e-17
Identities = 44/147 (29%), Positives = 79/147 (53%), Gaps = 1/147 (0%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
+ +G +G GS+A V A S +VAIK+I K + + + E+++ LKH +
Sbjct: 12 FKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVQNEVKIHCQLKHPS 71
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIR-KDQHIDETRGRRWFKQLVEAVDYCHERG 624
++ E ++ VY+V+E NG + ++ + + E R + Q++ + Y H G
Sbjct: 72 ILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLHSHG 131
Query: 625 VVHRDIKCENLLMDHGLNIKLSDFGFA 705
++HRD+ NLL+ +NIK++DFG A
Sbjct: 132 ILHRDLTLSNLLLTRNMNIKIADFGLA 158
>BC013879-1|AAH13879.1| 685|Homo sapiens polo-like kinase 2
(Drosophila) protein.
Length = 685
Score = 87.8 bits (208), Expect = 3e-17
Identities = 40/146 (27%), Positives = 79/146 (54%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y G+ +G G +A + +N A KII + + ++ + +EIE+ + L H++
Sbjct: 82 YCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRILHHKH 141
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+++F E +YI++EY S+ I++ + + E R + +Q+V + Y HE+ +
Sbjct: 142 VVQFYHYFEDKENIYILLEYCSRRSMAHILKARKVLTEPEVRYYLRQIVSGLKYLHEQEI 201
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFA 705
+HRD+K N ++ + +K+ DFG A
Sbjct: 202 LHRDLKLGNFFINEAMELKVGDFGLA 227
>AK131198-1|BAD18393.1| 706|Homo sapiens protein ( Homo sapiens
cDNA FLJ16039 fis, clone ADRGL2001554, weakly similar
to SERINE/THREONINE-PROTEIN KINASE PLK (EC 2.7.1.-). ).
Length = 706
Score = 87.8 bits (208), Expect = 3e-17
Identities = 44/147 (29%), Positives = 80/147 (54%), Gaps = 1/147 (0%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQ-APGDYLKKFLPREIEVVKGLKHE 444
Y +G+ IG G +A V +S R + A K++ K YL+KF+ EI + + L H
Sbjct: 39 YRVGKQIGKGGFAIVYELTSIRTGKKYAGKVVEKAGLTKPKYLEKFMS-EIRIHQSLDHP 97
Query: 445 NLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERG 624
++ + + E Y+++E N +L ++R + + E + + Q+++AV Y H+R
Sbjct: 98 HICKMYKHFEDNRYHYLILELCSNETLAHLLRVRECLTEPEVQYFLLQIIDAVSYLHKRC 157
Query: 625 VVHRDIKCENLLMDHGLNIKLSDFGFA 705
++HRD+K N+ +D L +K+ D G A
Sbjct: 158 IIHRDLKLGNIFLDENLEVKVGDLGLA 184
>AK098163-1|BAC05247.1| 372|Homo sapiens protein ( Homo sapiens
cDNA FLJ40844 fis, clone TRACH2014356, highly similar to
SERINE/THREONINE-PROTEIN KINASE SNK (EC 2.7.1.-). ).
Length = 372
Score = 87.8 bits (208), Expect = 3e-17
Identities = 40/146 (27%), Positives = 79/146 (54%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y G+ +G G +A + +N A KII + + ++ + +EIE+ + L H++
Sbjct: 75 YCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRILHHKH 134
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+++F E +YI++EY S+ I++ + + E R + +Q+V + Y HE+ +
Sbjct: 135 VVQFYHYFEDKENIYILLEYCSRRSMAHILKARKVLTEPEVRYYLRQIVSGLKYLHEQEI 194
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFA 705
+HRD+K N ++ + +K+ DFG A
Sbjct: 195 LHRDLKLGNFFINEAMELKVGDFGLA 220
>AF223574-1|AAF62897.1| 685|Homo sapiens serum-inducible kinase
protein.
Length = 685
Score = 87.8 bits (208), Expect = 3e-17
Identities = 40/146 (27%), Positives = 79/146 (54%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y G+ +G G +A + +N A KII + + ++ + +EIE+ + L H++
Sbjct: 82 YCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRILHHKH 141
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+++F E +YI++EY S+ I++ + + E R + +Q+V + Y HE+ +
Sbjct: 142 VVQFYHYFEDKENIYILLEYCSRRSMAHILKARKVLTEPEVRYYLRQIVSGLKYLHEQEI 201
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFA 705
+HRD+K N ++ + +K+ DFG A
Sbjct: 202 LHRDLKLGNFFINEAMELKVGDFGLA 227
>AF059617-1|AAC14573.1| 685|Homo sapiens serum-inducible kinase
protein.
Length = 685
Score = 87.8 bits (208), Expect = 3e-17
Identities = 40/146 (27%), Positives = 79/146 (54%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y G+ +G G +A + +N A KII + + ++ + +EIE+ + L H++
Sbjct: 82 YCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRILHHKH 141
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 627
+++F E +YI++EY S+ I++ + + E R + +Q+V + Y HE+ +
Sbjct: 142 VVQFYHYFEDKENIYILLEYCSRRSMAHILKARKVLTEPEVRYYLRQIVSGLKYLHEQEI 201
Query: 628 VHRDIKCENLLMDHGLNIKLSDFGFA 705
+HRD+K N ++ + +K+ DFG A
Sbjct: 202 LHRDLKLGNFFINEAMELKVGDFGLA 227
>U63333-1|AAB05809.1| 433|Homo sapiens serine/threonine protein
kinase protein.
Length = 433
Score = 87.4 bits (207), Expect = 5e-17
Identities = 48/151 (31%), Positives = 87/151 (57%), Gaps = 5/151 (3%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPG-DYLKKFLPREIEVVKGLKHE 444
Y++G +G GSY VK C+ A+KI+ K + + + +EI++++ L+H+
Sbjct: 49 YLMGDLLGEGSYGKVKEVLDSETLCRRAVKILKKKKLRRIPNGEANVKKEIQLLRRLRHK 108
Query: 445 NLIRFLQAI--ETTHRVYIVMEYAENG--SLLDIIRKDQHIDETRGRRWFKQLVEAVDYC 612
N+I+ + + E ++Y+VMEY G +LD + ++ + +F QL++ ++Y
Sbjct: 109 NVIQLVDVLYNEEKQKMYMVMEYCVCGMQEMLDSV-PEKRFPVCQAHGYFCQLIDGLEYL 167
Query: 613 HERGVVHRDIKCENLLMDHGLNIKLSDFGFA 705
H +G+VH+DIK NLL+ G +K+SD G A
Sbjct: 168 HSQGIVHKDIKPGNLLLTTGGTLKISDLGVA 198
>BC019334-1|AAH19334.1| 433|Homo sapiens serine/threonine kinase 11
protein.
Length = 433
Score = 87.4 bits (207), Expect = 5e-17
Identities = 48/151 (31%), Positives = 87/151 (57%), Gaps = 5/151 (3%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPG-DYLKKFLPREIEVVKGLKHE 444
Y++G +G GSY VK C+ A+KI+ K + + + +EI++++ L+H+
Sbjct: 49 YLMGDLLGEGSYGKVKEVLDSETLCRRAVKILKKKKLRRIPNGEANVKKEIQLLRRLRHK 108
Query: 445 NLIRFLQAI--ETTHRVYIVMEYAENG--SLLDIIRKDQHIDETRGRRWFKQLVEAVDYC 612
N+I+ + + E ++Y+VMEY G +LD + ++ + +F QL++ ++Y
Sbjct: 109 NVIQLVDVLYNEEKQKMYMVMEYCVCGMQEMLDSV-PEKRFPVCQAHGYFCQLIDGLEYL 167
Query: 613 HERGVVHRDIKCENLLMDHGLNIKLSDFGFA 705
H +G+VH+DIK NLL+ G +K+SD G A
Sbjct: 168 HSQGIVHKDIKPGNLLLTTGGTLKISDLGVA 198
>BC007981-1|AAH07981.1| 433|Homo sapiens serine/threonine kinase 11
protein.
Length = 433
Score = 87.4 bits (207), Expect = 5e-17
Identities = 48/151 (31%), Positives = 87/151 (57%), Gaps = 5/151 (3%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPG-DYLKKFLPREIEVVKGLKHE 444
Y++G +G GSY VK C+ A+KI+ K + + + +EI++++ L+H+
Sbjct: 49 YLMGDLLGEGSYGKVKEVLDSETLCRRAVKILKKKKLRRIPNGEANVKKEIQLLRRLRHK 108
Query: 445 NLIRFLQAI--ETTHRVYIVMEYAENG--SLLDIIRKDQHIDETRGRRWFKQLVEAVDYC 612
N+I+ + + E ++Y+VMEY G +LD + ++ + +F QL++ ++Y
Sbjct: 109 NVIQLVDVLYNEEKQKMYMVMEYCVCGMQEMLDSV-PEKRFPVCQAHGYFCQLIDGLEYL 167
Query: 613 HERGVVHRDIKCENLLMDHGLNIKLSDFGFA 705
H +G+VH+DIK NLL+ G +K+SD G A
Sbjct: 168 HSQGIVHKDIKPGNLLLTTGGTLKISDLGVA 198
>AF217978-1|AAG17221.1| 433|Homo sapiens unknown protein.
Length = 433
Score = 87.4 bits (207), Expect = 5e-17
Identities = 48/151 (31%), Positives = 87/151 (57%), Gaps = 5/151 (3%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPG-DYLKKFLPREIEVVKGLKHE 444
Y++G +G GSY VK C+ A+KI+ K + + + +EI++++ L+H+
Sbjct: 49 YLMGDLLGEGSYGKVKEVLDSETLCRRAVKILKKKKLRRIPNGEANVKKEIQLLRRLRHK 108
Query: 445 NLIRFLQAI--ETTHRVYIVMEYAENG--SLLDIIRKDQHIDETRGRRWFKQLVEAVDYC 612
N+I+ + + E ++Y+VMEY G +LD + ++ + +F QL++ ++Y
Sbjct: 109 NVIQLVDVLYNEEKQKMYMVMEYCVCGMQEMLDSV-PEKRFPVCQAHGYFCQLIDGLEYL 167
Query: 613 HERGVVHRDIKCENLLMDHGLNIKLSDFGFA 705
H +G+VH+DIK NLL+ G +K+SD G A
Sbjct: 168 HSQGIVHKDIKPGNLLLTTGGTLKISDLGVA 198
>AF055327-1|AAC15742.1| 433|Homo sapiens Peutz-Jeghers syndrome
protein protein.
Length = 433
Score = 87.4 bits (207), Expect = 5e-17
Identities = 48/151 (31%), Positives = 87/151 (57%), Gaps = 5/151 (3%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPG-DYLKKFLPREIEVVKGLKHE 444
Y++G +G GSY VK C+ A+KI+ K + + + +EI++++ L+H+
Sbjct: 49 YLMGDLLGEGSYGKVKEVLDSETLCRRAVKILKKKKLRRIPNGEANVKKEIQLLRRLRHK 108
Query: 445 NLIRFLQAI--ETTHRVYIVMEYAENG--SLLDIIRKDQHIDETRGRRWFKQLVEAVDYC 612
N+I+ + + E ++Y+VMEY G +LD + ++ + +F QL++ ++Y
Sbjct: 109 NVIQLVDVLYNEEKQKMYMVMEYCVCGMQEMLDSV-PEKRFPVCQAHGYFCQLIDGLEYL 167
Query: 613 HERGVVHRDIKCENLLMDHGLNIKLSDFGFA 705
H +G+VH+DIK NLL+ G +K+SD G A
Sbjct: 168 HSQGIVHKDIKPGNLLLTTGGTLKISDLGVA 198
>AF035625-1|AAC39527.1| 433|Homo sapiens serine threonine kinase 11
protein.
Length = 433
Score = 87.4 bits (207), Expect = 5e-17
Identities = 48/151 (31%), Positives = 87/151 (57%), Gaps = 5/151 (3%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPG-DYLKKFLPREIEVVKGLKHE 444
Y++G +G GSY VK C+ A+KI+ K + + + +EI++++ L+H+
Sbjct: 49 YLMGDLLGEGSYGKVKEVLDSETLCRRAVKILKKKKLRRIPNGEANVKKEIQLLRRLRHK 108
Query: 445 NLIRFLQAI--ETTHRVYIVMEYAENG--SLLDIIRKDQHIDETRGRRWFKQLVEAVDYC 612
N+I+ + + E ++Y+VMEY G +LD + ++ + +F QL++ ++Y
Sbjct: 109 NVIQLVDVLYNEEKQKMYMVMEYCVCGMQEMLDSV-PEKRFPVCQAHGYFCQLIDGLEYL 167
Query: 613 HERGVVHRDIKCENLLMDHGLNIKLSDFGFA 705
H +G+VH+DIK NLL+ G +K+SD G A
Sbjct: 168 HSQGIVHKDIKPGNLLLTTGGTLKISDLGVA 198
>AF032986-1|AAB97833.1| 433|Homo sapiens serine threonine kinase 11
protein.
Length = 433
Score = 87.4 bits (207), Expect = 5e-17
Identities = 48/151 (31%), Positives = 87/151 (57%), Gaps = 5/151 (3%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPG-DYLKKFLPREIEVVKGLKHE 444
Y++G +G GSY VK C+ A+KI+ K + + + +EI++++ L+H+
Sbjct: 49 YLMGDLLGEGSYGKVKEVLDSETLCRRAVKILKKKKLRRIPNGEANVKKEIQLLRRLRHK 108
Query: 445 NLIRFLQAI--ETTHRVYIVMEYAENG--SLLDIIRKDQHIDETRGRRWFKQLVEAVDYC 612
N+I+ + + E ++Y+VMEY G +LD + ++ + +F QL++ ++Y
Sbjct: 109 NVIQLVDVLYNEEKQKMYMVMEYCVCGMQEMLDSV-PEKRFPVCQAHGYFCQLIDGLEYL 167
Query: 613 HERGVVHRDIKCENLLMDHGLNIKLSDFGFA 705
H +G+VH+DIK NLL+ G +K+SD G A
Sbjct: 168 HSQGIVHKDIKPGNLLLTTGGTLKISDLGVA 198
>AB209553-1|BAD92790.1| 337|Homo sapiens serine/threonine protein
kinase 11 variant protein.
Length = 337
Score = 87.4 bits (207), Expect = 5e-17
Identities = 48/151 (31%), Positives = 87/151 (57%), Gaps = 5/151 (3%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPG-DYLKKFLPREIEVVKGLKHE 444
Y++G +G GSY VK C+ A+KI+ K + + + +EI++++ L+H+
Sbjct: 79 YLMGDLLGEGSYGKVKEVLDSETLCRRAVKILKKKKLRRIPNGEANVKKEIQLLRRLRHK 138
Query: 445 NLIRFLQAI--ETTHRVYIVMEYAENG--SLLDIIRKDQHIDETRGRRWFKQLVEAVDYC 612
N+I+ + + E ++Y+VMEY G +LD + ++ + +F QL++ ++Y
Sbjct: 139 NVIQLVDVLYNEEKQKMYMVMEYCVCGMQEMLDSV-PEKRFPVCQAHGYFCQLIDGLEYL 197
Query: 613 HERGVVHRDIKCENLLMDHGLNIKLSDFGFA 705
H +G+VH+DIK NLL+ G +K+SD G A
Sbjct: 198 HSQGIVHKDIKPGNLLLTTGGTLKISDLGVA 228
>BC034988-1|AAH34988.1| 1036|Homo sapiens ULK2 protein protein.
Length = 1036
Score = 87.0 bits (206), Expect = 6e-17
Identities = 48/151 (31%), Positives = 84/151 (55%), Gaps = 10/151 (6%)
Frame = +1
Query: 286 IGSGSYATV-KVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFL 462
+G G++A V + + + +VAIK I+K + L +EI+++K L+HEN++
Sbjct: 15 VGHGAFAVVFRGRHRQKTDWEVAIKSINKKNLSKSQI--LLGKEIKILKELQHENIVALY 72
Query: 463 QAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDI 642
E + V++VMEY G L D ++ + E R + Q+ A+ H +G++HRD+
Sbjct: 73 DVQELPNSVFLVMEYCNGGDLADYLQAKGTLSEDTIRVFLHQIAAAMRILHSKGIIHRDL 132
Query: 643 KCENLLMDH---------GLNIKLSDFGFAR 708
K +N+L+ + G+ IK++DFGFAR
Sbjct: 133 KPQNILLSYANRRKSSVSGIRIKIADFGFAR 163
>AB014523-1|BAA31598.2| 1100|Homo sapiens KIAA0623 protein protein.
Length = 1100
Score = 87.0 bits (206), Expect = 6e-17
Identities = 48/151 (31%), Positives = 84/151 (55%), Gaps = 10/151 (6%)
Frame = +1
Query: 286 IGSGSYATV-KVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFL 462
+G G++A V + + + +VAIK I+K + L +EI+++K L+HEN++
Sbjct: 79 VGHGAFAVVFRGRHRQKTDWEVAIKSINKKNLSKSQI--LLGKEIKILKELQHENIVALY 136
Query: 463 QAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDI 642
E + V++VMEY G L D ++ + E R + Q+ A+ H +G++HRD+
Sbjct: 137 DVQELPNSVFLVMEYCNGGDLADYLQAKGTLSEDTIRVFLHQIAAAMRILHSKGIIHRDL 196
Query: 643 KCENLLMDH---------GLNIKLSDFGFAR 708
K +N+L+ + G+ IK++DFGFAR
Sbjct: 197 KPQNILLSYANRRKSSVSGIRIKIADFGFAR 227
>AY574902-1|AAT81411.1| 1215|Homo sapiens regulated in COPD kinase
transcript variant 2 protein.
Length = 1215
Score = 86.6 bits (205), Expect = 8e-17
Identities = 61/190 (32%), Positives = 95/190 (50%), Gaps = 5/190 (2%)
Frame = +1
Query: 154 VRTHDNVLGEMSAEPTATVHSGVEAKTERKLTVLESHGYMLGRTIGSGSYATVKVASSDR 333
++ H + L E + + + +E L E + G +G G+Y TV + +
Sbjct: 910 IQRHSSGLRIYDREEKFLISNEKKIFSENSLKSEEPILWTKGEILGKGAYGTVYCGLTSQ 969
Query: 334 HNC----QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVM 501
QVA+ +K A +Y K L E++++K LKH N++ +L + V I M
Sbjct: 970 GQLIAVKQVALDTSNKLAAEKEYRK--LQEEVDLLKALKHVNIVAYLGTCLQENTVSIFM 1027
Query: 502 EYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCEN-LLMDHGLN 678
E+ GS+ II + + E ++ KQ+++ V Y HE VVHRDIK N +LM G+
Sbjct: 1028 EFVPGGSISSIINRFGPLPEMVFCKYTKQILQGVAYLHENCVVHRDIKGNNVMLMPTGI- 1086
Query: 679 IKLSDFGFAR 708
IKL DFG AR
Sbjct: 1087 IKLIDFGCAR 1096
>AY574901-1|AAT81410.1| 1328|Homo sapiens regulated in COPD kinase
transcript variant 1 protein.
Length = 1328
Score = 86.6 bits (205), Expect = 8e-17
Identities = 61/190 (32%), Positives = 95/190 (50%), Gaps = 5/190 (2%)
Frame = +1
Query: 154 VRTHDNVLGEMSAEPTATVHSGVEAKTERKLTVLESHGYMLGRTIGSGSYATVKVASSDR 333
++ H + L E + + + +E L E + G +G G+Y TV + +
Sbjct: 1023 IQRHSSGLRIYDREEKFLISNEKKIFSENSLKSEEPILWTKGEILGKGAYGTVYCGLTSQ 1082
Query: 334 HNC----QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVM 501
QVA+ +K A +Y K L E++++K LKH N++ +L + V I M
Sbjct: 1083 GQLIAVKQVALDTSNKLAAEKEYRK--LQEEVDLLKALKHVNIVAYLGTCLQENTVSIFM 1140
Query: 502 EYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCEN-LLMDHGLN 678
E+ GS+ II + + E ++ KQ+++ V Y HE VVHRDIK N +LM G+
Sbjct: 1141 EFVPGGSISSIINRFGPLPEMVFCKYTKQILQGVAYLHENCVVHRDIKGNNVMLMPTGI- 1199
Query: 679 IKLSDFGFAR 708
IKL DFG AR
Sbjct: 1200 IKLIDFGCAR 1209
>EF644172-1|ABR45718.1| 433|Homo sapiens polarization-related
protein LKB1 protein.
Length = 433
Score = 85.4 bits (202), Expect = 2e-16
Identities = 47/151 (31%), Positives = 86/151 (56%), Gaps = 5/151 (3%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPG-DYLKKFLPREIEVVKGLKHE 444
Y++G +G GSY VK C+ A+KI+ K + + + +EI++++ L+H+
Sbjct: 49 YLMGDLLGEGSYGKVKEVLDSETLCRRAVKILKKKKLRRIPNGEANVKKEIQLLRRLRHK 108
Query: 445 NLIRFLQAI--ETTHRVYIVMEYAENG--SLLDIIRKDQHIDETRGRRWFKQLVEAVDYC 612
N+I+ + + E ++Y+VMEY G +LD + ++ + +F L++ ++Y
Sbjct: 109 NVIQLVDVLYNEEKQKMYMVMEYCVCGMQEMLDSV-PEKRFPVCQAHGYFCHLIDGLEYL 167
Query: 613 HERGVVHRDIKCENLLMDHGLNIKLSDFGFA 705
H +G+VH+DIK NLL+ G +K+SD G A
Sbjct: 168 HSQGIVHKDIKPVNLLLTAGGTLKISDLGVA 198
>AF217975-1|AAG17218.1| 322|Homo sapiens unknown protein.
Length = 322
Score = 85.4 bits (202), Expect = 2e-16
Identities = 54/154 (35%), Positives = 88/154 (57%), Gaps = 9/154 (5%)
Frame = +1
Query: 274 LGRTIGSGSYATVKVASSDRHNCQ-VAIKIISKFQAPGDYLKKFLPR-----EIEVVKGL 435
+ +T+GSG+ VK+A +R C+ VAIKIISK + ++ P EIE++K L
Sbjct: 1 MSKTLGSGACGEVKLAF-ERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEILKKL 59
Query: 436 KHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCH 615
H +I+ + YIV+E E G L D + ++ + E + +F Q++ AV Y H
Sbjct: 60 NHPCIIKIKNFFDAED-YYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLLAVQYLH 118
Query: 616 ERGVVHRDIKCENLLM---DHGLNIKLSDFGFAR 708
E G++HRD+K EN+L+ + IK++DFG ++
Sbjct: 119 ENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSK 152
>AF090421-1|AAC69577.1| 809|Homo sapiens ribosome S6 protein kinase
protein.
Length = 809
Score = 85.4 bits (202), Expect = 2e-16
Identities = 49/147 (33%), Positives = 78/147 (53%), Gaps = 4/147 (2%)
Frame = +1
Query: 280 RTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLK-HENLIR 456
+ +G GS++ + + N + +KIISK ++ +EI +K + H N+++
Sbjct: 430 KPLGEGSFSICRKCVHKKSNQALQVKIISK------RMEANTQKEITALKLCEGHPNIVK 483
Query: 457 FLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHR 636
+ ++VME G L D +RK +H ET ++LV A+ + H+ GVVHR
Sbjct: 484 LHEVFHDQLHTFLVMELLNGGELFDALRKKKHFSETEASYIMRKLVSALSHMHDLGVVHR 543
Query: 637 DIKCENLLM---DHGLNIKLSDFGFAR 708
D+K ENLL + L IK+ DFGFAR
Sbjct: 544 DLKPENLLFTDENDNLEIKIIDFGFAR 570
Score = 59.3 bits (137), Expect = 1e-08
Identities = 35/153 (22%), Positives = 81/153 (52%), Gaps = 6/153 (3%)
Frame = +1
Query: 268 YMLGRTIGSGSYATV----KVASSDRHNCQVAIKIISKFQ-APGDYLKKFLPREIEVVKG 432
+ L + +G+G+Y V K++ D A+K++ K + E +V++
Sbjct: 49 FELLKVLGTGAYGKVFLVRKISGHDTGKLY-AMKVLKKATIVQKAKTTEHTRTERQVLEH 107
Query: 433 LKHEN-LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDY 609
++ L+ A +T +++++++Y G L + + + E + + ++V A+++
Sbjct: 108 IRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALEH 167
Query: 610 CHERGVVHRDIKCENLLMDHGLNIKLSDFGFAR 708
H+ G+++RDIK EN+L+D ++ L+DFG ++
Sbjct: 168 LHKLGIIYRDIKLENILLDSNGHVVLTDFGLSK 200
>BC019916-1|AAH19916.2| 506|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 3 protein.
Length = 506
Score = 85.0 bits (201), Expect = 2e-16
Identities = 49/150 (32%), Positives = 78/150 (52%), Gaps = 3/150 (2%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPR-EIEVVKGLKHE 444
YM+ R IG GS+ + + N A+K I + P + R E ++ +KH
Sbjct: 4 YMVLRMIGEGSFGRALLVQHESSNQMFAMKEI---RLPKSFSNTQNSRKEAVLLAKMKHP 60
Query: 445 NLIRFLQAIETTHRVYIVMEYAENGSLLDIIR--KDQHIDETRGRRWFKQLVEAVDYCHE 618
N++ F ++ E +YIVMEY + G L+ I+ K + E WF Q+ V++ H+
Sbjct: 61 NIVAFKESFEAEGHLYIVMEYCDGGDLMQKIKQQKGKLFPEDMILNWFTQMCLGVNHIHK 120
Query: 619 RGVVHRDIKCENLLMDHGLNIKLSDFGFAR 708
+ V+HRDIK +N+ + +KL DFG AR
Sbjct: 121 KRVLHRDIKSKNIFLTQNGKVKLGDFGSAR 150
>AL139082-7|CAI12895.1| 507|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 3 protein.
Length = 507
Score = 85.0 bits (201), Expect = 2e-16
Identities = 49/150 (32%), Positives = 78/150 (52%), Gaps = 3/150 (2%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPR-EIEVVKGLKHE 444
YM+ R IG GS+ + + N A+K I + P + R E ++ +KH
Sbjct: 4 YMVLRMIGEGSFGRALLVQHESSNQMFAMKEI---RLPKSFSNTQNSRKEAVLLAKMKHP 60
Query: 445 NLIRFLQAIETTHRVYIVMEYAENGSLLDIIR--KDQHIDETRGRRWFKQLVEAVDYCHE 618
N++ F ++ E +YIVMEY + G L+ I+ K + E WF Q+ V++ H+
Sbjct: 61 NIVAFKESFEAEGHLYIVMEYCDGGDLMQKIKQQKGKLFPEDMILNWFTQMCLGVNHIHK 120
Query: 619 RGVVHRDIKCENLLMDHGLNIKLSDFGFAR 708
+ V+HRDIK +N+ + +KL DFG AR
Sbjct: 121 KRVLHRDIKSKNIFLTQNGKVKLGDFGSAR 150
>AK131359-1|BAD18511.1| 510|Homo sapiens protein ( Homo sapiens
cDNA FLJ16392 fis, clone TRACH2020048, moderately
similar to Mus musculus serine/threonine-protein kinase
NEK3 (Nek3) mRNA. ).
Length = 510
Score = 85.0 bits (201), Expect = 2e-16
Identities = 49/150 (32%), Positives = 78/150 (52%), Gaps = 3/150 (2%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPR-EIEVVKGLKHE 444
YM+ R IG GS+ + + N A+K I + P + R E ++ +KH
Sbjct: 25 YMVLRMIGEGSFGRALLVQHESSNQMFAMKEI---RLPKSFSNTQNSRKEAVLLAKMKHP 81
Query: 445 NLIRFLQAIETTHRVYIVMEYAENGSLLDIIR--KDQHIDETRGRRWFKQLVEAVDYCHE 618
N++ F ++ E +YIVMEY + G L+ I+ K + E WF Q+ V++ H+
Sbjct: 82 NIVAFKESFEAEGHLYIVMEYCDGGDLMQKIKQQKGKLFPEDMILNWFTQMCLGVNHIHK 141
Query: 619 RGVVHRDIKCENLLMDHGLNIKLSDFGFAR 708
+ V+HRDIK +N+ + +KL DFG AR
Sbjct: 142 KRVLHRDIKSKNIFLTQNGKVKLGDFGSAR 171
>AF080000-1|AAD23915.1| 802|Homo sapiens RSK-like protein kinase
RLPK protein.
Length = 802
Score = 84.6 bits (200), Expect = 3e-16
Identities = 50/147 (34%), Positives = 78/147 (53%), Gaps = 4/147 (2%)
Frame = +1
Query: 280 RTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLK-HENLIR 456
+ +G GS++ + + N A+KIISK ++ +EI +K + H N+++
Sbjct: 430 KPLGEGSFSICRKCVHKKSNQAFAVKIISK------RMEANTQKEITALKLCEGHPNIVK 483
Query: 457 FLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHR 636
+ ++VME G L + I+K +H ET ++LV AV + H+ GVVHR
Sbjct: 484 LHEVFHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMHDVGVVHR 543
Query: 637 DIKCENLLM---DHGLNIKLSDFGFAR 708
D+K ENLL + L IK+ DFGFAR
Sbjct: 544 DLKPENLLFTDENDNLEIKIIDFGFAR 570
Score = 59.3 bits (137), Expect = 1e-08
Identities = 35/153 (22%), Positives = 81/153 (52%), Gaps = 6/153 (3%)
Frame = +1
Query: 268 YMLGRTIGSGSYATV----KVASSDRHNCQVAIKIISKFQ-APGDYLKKFLPREIEVVKG 432
+ L + +G+G+Y V K++ D A+K++ K + E +V++
Sbjct: 49 FELLKVLGTGAYGKVFLVRKISGHDTGKLY-AMKVLKKATIVQKAKTTEHTRTERQVLEH 107
Query: 433 LKHEN-LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDY 609
++ L+ A +T +++++++Y G L + + + E + + ++V A+++
Sbjct: 108 IRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALEH 167
Query: 610 CHERGVVHRDIKCENLLMDHGLNIKLSDFGFAR 708
H+ G+++RDIK EN+L+D ++ L+DFG ++
Sbjct: 168 LHKLGIIYRDIKLENILLDSNGHVVLTDFGLSK 200
>AF074393-1|AAC31171.1| 802|Homo sapiens nuclear mitogen- and
stress-activated protein kinase-1 protein.
Length = 802
Score = 84.6 bits (200), Expect = 3e-16
Identities = 50/147 (34%), Positives = 78/147 (53%), Gaps = 4/147 (2%)
Frame = +1
Query: 280 RTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLK-HENLIR 456
+ +G GS++ + + N A+KIISK ++ +EI +K + H N+++
Sbjct: 430 KPLGEGSFSICRKCVHKKSNQAFAVKIISK------RMEANTQKEITALKLCEGHPNIVK 483
Query: 457 FLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHR 636
+ ++VME G L + I+K +H ET ++LV AV + H+ GVVHR
Sbjct: 484 LHEVFHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMHDVGVVHR 543
Query: 637 DIKCENLLM---DHGLNIKLSDFGFAR 708
D+K ENLL + L IK+ DFGFAR
Sbjct: 544 DLKPENLLFTDENDNLEIKIIDFGFAR 570
Score = 59.3 bits (137), Expect = 1e-08
Identities = 35/153 (22%), Positives = 81/153 (52%), Gaps = 6/153 (3%)
Frame = +1
Query: 268 YMLGRTIGSGSYATV----KVASSDRHNCQVAIKIISKFQ-APGDYLKKFLPREIEVVKG 432
+ L + +G+G+Y V K++ D A+K++ K + E +V++
Sbjct: 49 FELLKVLGTGAYGKVFLVRKISGHDTGKLY-AMKVLKKATIVQKAKTTEHTRTERQVLEH 107
Query: 433 LKHEN-LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDY 609
++ L+ A +T +++++++Y G L + + + E + + ++V A+++
Sbjct: 108 IRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALEH 167
Query: 610 CHERGVVHRDIKCENLLMDHGLNIKLSDFGFAR 708
H+ G+++RDIK EN+L+D ++ L+DFG ++
Sbjct: 168 LHKLGIIYRDIKLENILLDSNGHVVLTDFGLSK 200
>Y15801-1|CAA75792.1| 277|Homo sapiens protein kinase protein.
Length = 277
Score = 84.2 bits (199), Expect = 4e-16
Identities = 43/142 (30%), Positives = 75/142 (52%)
Frame = +1
Query: 283 TIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFL 462
T+G+G++ V + A+K++S ++ + E V+K + H LIR
Sbjct: 54 TMGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRRKQEQHVHNEKSVLKEVSHPFLIRLF 113
Query: 463 QAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDI 642
+Y++MEY G L +R H T G + +++ A++Y H + +V+RD+
Sbjct: 114 WTWHEERFLYMLMEYVPGGELFSYLRNRGHFSSTTGLFYSAEIICAIEYLHSKEIVYRDL 173
Query: 643 KCENLLMDHGLNIKLSDFGFAR 708
K EN+L+D +IKL+DFGFA+
Sbjct: 174 KPENILLDRDGHIKLTDFGFAK 195
>Y13927-1|CAA74244.1| 277|Homo sapiens protein kinase protein.
Length = 277
Score = 84.2 bits (199), Expect = 4e-16
Identities = 43/142 (30%), Positives = 75/142 (52%)
Frame = +1
Query: 283 TIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFL 462
T+G+G++ V + A+K++S ++ + E V+K + H LIR
Sbjct: 54 TMGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRRKQEQHVHNEKSVLKEVSHPFLIRLF 113
Query: 463 QAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDI 642
+Y++MEY G L +R H T G + +++ A++Y H + +V+RD+
Sbjct: 114 WTWHEERFLYMLMEYVPGGELFSYLRNRGHFSSTTGLFYSAEIICAIEYLHSKEIVYRDL 173
Query: 643 KCENLLMDHGLNIKLSDFGFAR 708
K EN+L+D +IKL+DFGFA+
Sbjct: 174 KPENILLDRDGHIKLTDFGFAK 195
>BC074852-1|AAH74852.1| 277|Homo sapiens protein kinase, Y-linked
protein.
Length = 277
Score = 84.2 bits (199), Expect = 4e-16
Identities = 43/142 (30%), Positives = 75/142 (52%)
Frame = +1
Query: 283 TIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFL 462
T+G+G++ V + A+K++S ++ + E V+K + H LIR
Sbjct: 54 TMGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRRKQEQHVHNEKSVLKEVSHPFLIRLF 113
Query: 463 QAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDI 642
+Y++MEY G L +R H T G + +++ A++Y H + +V+RD+
Sbjct: 114 WTWHEERFLYMLMEYVPGGELFSYLRNRGHFSSTTGLFYSAEIICAIEYLHSKEIVYRDL 173
Query: 643 KCENLLMDHGLNIKLSDFGFAR 708
K EN+L+D +IKL+DFGFA+
Sbjct: 174 KPENILLDRDGHIKLTDFGFAK 195
>BC074851-1|AAH74851.1| 277|Homo sapiens protein kinase, Y-linked
protein.
Length = 277
Score = 84.2 bits (199), Expect = 4e-16
Identities = 43/142 (30%), Positives = 75/142 (52%)
Frame = +1
Query: 283 TIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFL 462
T+G+G++ V + A+K++S ++ + E V+K + H LIR
Sbjct: 54 TMGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRRKQEQHVHNEKSVLKEVSHPFLIRLF 113
Query: 463 QAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDI 642
+Y++MEY G L +R H T G + +++ A++Y H + +V+RD+
Sbjct: 114 WTWHEERFLYMLMEYVPGGELFSYLRNRGHFSSTTGLFYSAEIICAIEYLHSKEIVYRDL 173
Query: 643 KCENLLMDHGLNIKLSDFGFAR 708
K EN+L+D +IKL+DFGFA+
Sbjct: 174 KPENILLDRDGHIKLTDFGFAK 195
>BC035745-1|AAH35745.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 83.8 bits (198), Expect = 6e-16
Identities = 47/145 (32%), Positives = 76/145 (52%), Gaps = 3/145 (2%)
Frame = +1
Query: 283 TIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFL 462
T+G+G+++ V +A A+K I K G + + EI V++ +KHEN++
Sbjct: 28 TLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGK--ESSIENEIAVLRKIKHENIVALE 85
Query: 463 QAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDI 642
E+ + +Y+VM+ G L D I + E +Q+++AV Y H G+VHRD+
Sbjct: 86 DIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDL 145
Query: 643 KCENLL---MDHGLNIKLSDFGFAR 708
K ENLL D I +SDFG ++
Sbjct: 146 KPENLLYYSQDEESKIMISDFGLSK 170
>BC022558-1|AAH22558.1| 344|Homo sapiens CAMK2D protein protein.
Length = 344
Score = 83.8 bits (198), Expect = 6e-16
Identities = 51/150 (34%), Positives = 79/150 (52%), Gaps = 4/150 (2%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIIS-KFQAPGDYLKKFLPREIEVVKGLKHE 444
Y L +G G+++ V+ + A KII+ K + D+ K L RE + + LKH
Sbjct: 14 YQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQK--LEREARICRLLKHP 71
Query: 445 NLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERG 624
N++R +I Y+V + G L + I ++ E +Q++EAV +CH+ G
Sbjct: 72 NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMG 131
Query: 625 VVHRDIKCENLLM---DHGLNIKLSDFGFA 705
VVHRD+K ENLL+ G +KL+DFG A
Sbjct: 132 VVHRDLKPENLLLASKSKGAAVKLADFGLA 161
>AL731559-2|CAI14675.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 83.8 bits (198), Expect = 6e-16
Identities = 47/145 (32%), Positives = 76/145 (52%), Gaps = 3/145 (2%)
Frame = +1
Query: 283 TIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFL 462
T+G+G+++ V +A A+K I K G + + EI V++ +KHEN++
Sbjct: 28 TLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGK--ESSIENEIAVLRKIKHENIVALE 85
Query: 463 QAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDI 642
E+ + +Y+VM+ G L D I + E +Q+++AV Y H G+VHRD+
Sbjct: 86 DIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDL 145
Query: 643 KCENLL---MDHGLNIKLSDFGFAR 708
K ENLL D I +SDFG ++
Sbjct: 146 KPENLLYYSQDEESKIMISDFGLSK 170
>AL731559-1|CAI14674.1| 357|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 357
Score = 83.8 bits (198), Expect = 6e-16
Identities = 47/145 (32%), Positives = 76/145 (52%), Gaps = 3/145 (2%)
Frame = +1
Query: 283 TIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFL 462
T+G+G+++ V +A A+K I K G + + EI V++ +KHEN++
Sbjct: 28 TLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGK--ESSIENEIAVLRKIKHENIVALE 85
Query: 463 QAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDI 642
E+ + +Y+VM+ G L D I + E +Q+++AV Y H G+VHRD+
Sbjct: 86 DIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDL 145
Query: 643 KCENLL---MDHGLNIKLSDFGFAR 708
K ENLL D I +SDFG ++
Sbjct: 146 KPENLLYYSQDEESKIMISDFGLSK 170
>AL512783-2|CAH74036.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 83.8 bits (198), Expect = 6e-16
Identities = 47/145 (32%), Positives = 76/145 (52%), Gaps = 3/145 (2%)
Frame = +1
Query: 283 TIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFL 462
T+G+G+++ V +A A+K I K G + + EI V++ +KHEN++
Sbjct: 28 TLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGK--ESSIENEIAVLRKIKHENIVALE 85
Query: 463 QAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDI 642
E+ + +Y+VM+ G L D I + E +Q+++AV Y H G+VHRD+
Sbjct: 86 DIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDL 145
Query: 643 KCENLL---MDHGLNIKLSDFGFAR 708
K ENLL D I +SDFG ++
Sbjct: 146 KPENLLYYSQDEESKIMISDFGLSK 170
>AL512783-1|CAH74035.1| 357|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 357
Score = 83.8 bits (198), Expect = 6e-16
Identities = 47/145 (32%), Positives = 76/145 (52%), Gaps = 3/145 (2%)
Frame = +1
Query: 283 TIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFL 462
T+G+G+++ V +A A+K I K G + + EI V++ +KHEN++
Sbjct: 28 TLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGK--ESSIENEIAVLRKIKHENIVALE 85
Query: 463 QAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDI 642
E+ + +Y+VM+ G L D I + E +Q+++AV Y H G+VHRD+
Sbjct: 86 DIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDL 145
Query: 643 KCENLL---MDHGLNIKLSDFGFAR 708
K ENLL D I +SDFG ++
Sbjct: 146 KPENLLYYSQDEESKIMISDFGLSK 170
>AL512284-2|CAH71694.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 83.8 bits (198), Expect = 6e-16
Identities = 47/145 (32%), Positives = 76/145 (52%), Gaps = 3/145 (2%)
Frame = +1
Query: 283 TIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFL 462
T+G+G+++ V +A A+K I K G + + EI V++ +KHEN++
Sbjct: 28 TLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGK--ESSIENEIAVLRKIKHENIVALE 85
Query: 463 QAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDI 642
E+ + +Y+VM+ G L D I + E +Q+++AV Y H G+VHRD+
Sbjct: 86 DIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDL 145
Query: 643 KCENLL---MDHGLNIKLSDFGFAR 708
K ENLL D I +SDFG ++
Sbjct: 146 KPENLLYYSQDEESKIMISDFGLSK 170
>AL512284-1|CAH71693.1| 357|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 357
Score = 83.8 bits (198), Expect = 6e-16
Identities = 47/145 (32%), Positives = 76/145 (52%), Gaps = 3/145 (2%)
Frame = +1
Query: 283 TIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFL 462
T+G+G+++ V +A A+K I K G + + EI V++ +KHEN++
Sbjct: 28 TLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGK--ESSIENEIAVLRKIKHENIVALE 85
Query: 463 QAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDI 642
E+ + +Y+VM+ G L D I + E +Q+++AV Y H G+VHRD+
Sbjct: 86 DIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDL 145
Query: 643 KCENLL---MDHGLNIKLSDFGFAR 708
K ENLL D I +SDFG ++
Sbjct: 146 KPENLLYYSQDEESKIMISDFGLSK 170
>AL391314-2|CAI14410.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 83.8 bits (198), Expect = 6e-16
Identities = 47/145 (32%), Positives = 76/145 (52%), Gaps = 3/145 (2%)
Frame = +1
Query: 283 TIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFL 462
T+G+G+++ V +A A+K I K G + + EI V++ +KHEN++
Sbjct: 28 TLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGK--ESSIENEIAVLRKIKHENIVALE 85
Query: 463 QAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDI 642
E+ + +Y+VM+ G L D I + E +Q+++AV Y H G+VHRD+
Sbjct: 86 DIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDL 145
Query: 643 KCENLL---MDHGLNIKLSDFGFAR 708
K ENLL D I +SDFG ++
Sbjct: 146 KPENLLYYSQDEESKIMISDFGLSK 170
>AL391314-1|CAI14409.1| 357|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 357
Score = 83.8 bits (198), Expect = 6e-16
Identities = 47/145 (32%), Positives = 76/145 (52%), Gaps = 3/145 (2%)
Frame = +1
Query: 283 TIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFL 462
T+G+G+++ V +A A+K I K G + + EI V++ +KHEN++
Sbjct: 28 TLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGK--ESSIENEIAVLRKIKHENIVALE 85
Query: 463 QAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDI 642
E+ + +Y+VM+ G L D I + E +Q+++AV Y H G+VHRD+
Sbjct: 86 DIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDL 145
Query: 643 KCENLL---MDHGLNIKLSDFGFAR 708
K ENLL D I +SDFG ++
Sbjct: 146 KPENLLYYSQDEESKIMISDFGLSK 170
>AF286366-1|AAG00534.1| 357|Homo sapiens CamKI-like protein kinase
protein.
Length = 357
Score = 83.8 bits (198), Expect = 6e-16
Identities = 47/145 (32%), Positives = 76/145 (52%), Gaps = 3/145 (2%)
Frame = +1
Query: 283 TIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFL 462
T+G+G+++ V +A A+K I K G + + EI V++ +KHEN++
Sbjct: 28 TLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGK--ESSIENEIAVLRKIKHENIVALE 85
Query: 463 QAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDI 642
E+ + +Y+VM+ G L D I + E +Q+++AV Y H G+VHRD+
Sbjct: 86 DIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDL 145
Query: 643 KCENLL---MDHGLNIKLSDFGFAR 708
K ENLL D I +SDFG ++
Sbjct: 146 KPENLLYYSQDEESKIMISDFGLSK 170
>AB081726-1|BAC19846.1| 385|Homo sapiens CaM-kinase I delta
protein.
Length = 385
Score = 83.8 bits (198), Expect = 6e-16
Identities = 47/145 (32%), Positives = 76/145 (52%), Gaps = 3/145 (2%)
Frame = +1
Query: 283 TIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFL 462
T+G+G+++ V +A A+K I K G + + EI V++ +KHEN++
Sbjct: 28 TLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGK--ESSIENEIAVLRKIKHENIVALE 85
Query: 463 QAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDI 642
E+ + +Y+VM+ G L D I + E +Q+++AV Y H G+VHRD+
Sbjct: 86 DIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDL 145
Query: 643 KCENLL---MDHGLNIKLSDFGFAR 708
K ENLL D I +SDFG ++
Sbjct: 146 KPENLLYYSQDEESKIMISDFGLSK 170
>BC114491-1|AAI14492.1| 1189|Homo sapiens NEK1 protein protein.
Length = 1189
Score = 83.4 bits (197), Expect = 7e-16
Identities = 45/149 (30%), Positives = 77/149 (51%), Gaps = 2/149 (1%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y+ + IG GS+ + S Q IK I+ ++ RE+ V+ +KH N
Sbjct: 4 YVRLQKIGEGSFGKAILVKSTEDGRQYVIKEIN-ISRMSSKEREESRREVAVLANMKHPN 62
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHI--DETRGRRWFKQLVEAVDYCHER 621
++++ ++ E +YIVM+Y E G L I + + E + WF Q+ A+ + H+R
Sbjct: 63 IVQYRESFEENGSLYIVMDYCEGGDLFKRINAQKGVLFQEDQILDWFVQICLALKHVHDR 122
Query: 622 GVVHRDIKCENLLMDHGLNIKLSDFGFAR 708
++HRDIK +N+ + ++L DFG AR
Sbjct: 123 KILHRDIKSQNIFLTKDGTVQLGDFGIAR 151
>BC040457-1|AAH40457.1| 478|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II alpha protein.
Length = 478
Score = 83.4 bits (197), Expect = 7e-16
Identities = 50/150 (33%), Positives = 79/150 (52%), Gaps = 4/150 (2%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIIS-KFQAPGDYLKKFLPREIEVVKGLKHE 444
Y L +G G+++ V+ + A KII+ K + D+ K L RE + + LKH
Sbjct: 13 YQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQK--LEREARICRLLKHP 70
Query: 445 NLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERG 624
N++R +I Y++ + G L + I ++ E +Q++EAV +CH+ G
Sbjct: 71 NIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMG 130
Query: 625 VVHRDIKCENLLMD---HGLNIKLSDFGFA 705
VVHRD+K ENLL+ G +KL+DFG A
Sbjct: 131 VVHRDLKPENLLLASKLKGAAVKLADFGLA 160
>BC015147-1|AAH15147.1| 403|Homo sapiens Unknown (protein for
IMAGE:4063881) protein.
Length = 403
Score = 83.4 bits (197), Expect = 7e-16
Identities = 45/149 (30%), Positives = 77/149 (51%), Gaps = 2/149 (1%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y+ + IG GS+ + S Q IK I+ ++ RE+ V+ +KH N
Sbjct: 4 YVRLQKIGEGSFGKAILVKSTEDGRQYVIKEIN-ISRMSSKEREESRREVAVLANMKHPN 62
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHI--DETRGRRWFKQLVEAVDYCHER 621
++++ ++ E +YIVM+Y E G L I + + E + WF Q+ A+ + H+R
Sbjct: 63 IVQYRESFEENGSLYIVMDYCEGGDLFKRINAQKGVLFQEDQILDWFVQICLALKHVHDR 122
Query: 622 GVVHRDIKCENLLMDHGLNIKLSDFGFAR 708
++HRDIK +N+ + ++L DFG AR
Sbjct: 123 KILHRDIKSQNIFLTKDGTVQLGDFGIAR 151
>AF145711-1|AAD30559.1| 489|Homo sapiens
calcium/calmodulin-dependent protein kinase II alpha-B
subunit protein.
Length = 489
Score = 83.4 bits (197), Expect = 7e-16
Identities = 50/150 (33%), Positives = 79/150 (52%), Gaps = 4/150 (2%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIIS-KFQAPGDYLKKFLPREIEVVKGLKHE 444
Y L +G G+++ V+ + A KII+ K + D+ K L RE + + LKH
Sbjct: 13 YQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQK--LEREARICRLLKHP 70
Query: 445 NLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERG 624
N++R +I Y++ + G L + I ++ E +Q++EAV +CH+ G
Sbjct: 71 NIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMG 130
Query: 625 VVHRDIKCENLLMD---HGLNIKLSDFGFA 705
VVHRD+K ENLL+ G +KL+DFG A
Sbjct: 131 VVHRDLKPENLLLASKLKGAAVKLADFGLA 160
>AF145710-1|AAD30558.1| 478|Homo sapiens
calcium/calmodulin-dependent protein kinase II alpha
subunit protein.
Length = 478
Score = 83.4 bits (197), Expect = 7e-16
Identities = 50/150 (33%), Positives = 79/150 (52%), Gaps = 4/150 (2%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIIS-KFQAPGDYLKKFLPREIEVVKGLKHE 444
Y L +G G+++ V+ + A KII+ K + D+ K L RE + + LKH
Sbjct: 13 YQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQK--LEREARICRLLKHP 70
Query: 445 NLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERG 624
N++R +I Y++ + G L + I ++ E +Q++EAV +CH+ G
Sbjct: 71 NIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMG 130
Query: 625 VVHRDIKCENLLMD---HGLNIKLSDFGFA 705
VVHRD+K ENLL+ G +KL+DFG A
Sbjct: 131 VVHRDLKPENLLLASKLKGAAVKLADFGLA 160
>AF091486-1|AAD55815.1| 478|Homo sapiens calmodulin-dependent
protein kinase II alpha protein.
Length = 478
Score = 83.4 bits (197), Expect = 7e-16
Identities = 50/150 (33%), Positives = 79/150 (52%), Gaps = 4/150 (2%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIIS-KFQAPGDYLKKFLPREIEVVKGLKHE 444
Y L +G G+++ V+ + A KII+ K + D+ K L RE + + LKH
Sbjct: 13 YQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQK--LEREARICRLLKHP 70
Query: 445 NLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERG 624
N++R +I Y++ + G L + I ++ E +Q++EAV +CH+ G
Sbjct: 71 NIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMG 130
Query: 625 VVHRDIKCENLLMD---HGLNIKLSDFGFA 705
VVHRD+K ENLL+ G +KL+DFG A
Sbjct: 131 VVHRDLKPENLLLASKLKGAAVKLADFGLA 160
>AB067488-1|BAB67794.1| 1265|Homo sapiens KIAA1901 protein protein.
Length = 1265
Score = 83.4 bits (197), Expect = 7e-16
Identities = 45/149 (30%), Positives = 77/149 (51%), Gaps = 2/149 (1%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 447
Y+ + IG GS+ + S Q IK I+ ++ RE+ V+ +KH N
Sbjct: 11 YVRLQKIGEGSFGKAILVKSTEDGRQYVIKEIN-ISRMSSKEREESRREVAVLANMKHPN 69
Query: 448 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHI--DETRGRRWFKQLVEAVDYCHER 621
++++ ++ E +YIVM+Y E G L I + + E + WF Q+ A+ + H+R
Sbjct: 70 IVQYRESFEENGSLYIVMDYCEGGDLFKRINAQKGVLFQEDQILDWFVQICLALKHVHDR 129
Query: 622 GVVHRDIKCENLLMDHGLNIKLSDFGFAR 708
++HRDIK +N+ + ++L DFG AR
Sbjct: 130 KILHRDIKSQNIFLTKDGTVQLGDFGIAR 158
>AB023185-1|BAA76812.1| 527|Homo sapiens KIAA0968 protein protein.
Length = 527
Score = 83.4 bits (197), Expect = 7e-16
Identities = 50/150 (33%), Positives = 79/150 (52%), Gaps = 4/150 (2%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIIS-KFQAPGDYLKKFLPREIEVVKGLKHE 444
Y L +G G+++ V+ + A KII+ K + D+ K L RE + + LKH
Sbjct: 62 YQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQK--LEREARICRLLKHP 119
Query: 445 NLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERG 624
N++R +I Y++ + G L + I ++ E +Q++EAV +CH+ G
Sbjct: 120 NIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMG 179
Query: 625 VVHRDIKCENLLMD---HGLNIKLSDFGFA 705
VVHRD+K ENLL+ G +KL+DFG A
Sbjct: 180 VVHRDLKPENLLLASKLKGAAVKLADFGLA 209
>U23460-1|AAC99802.1| 664|Homo sapiens proline rich
calmodulin-dependent protein kinase protein.
Length = 664
Score = 83.0 bits (196), Expect = 1e-15
Identities = 52/150 (34%), Positives = 79/150 (52%), Gaps = 4/150 (2%)
Frame = +1
Query: 268 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIIS-KFQAPGDYLKKFLPREIEVVKGLKHE 444
Y L IG G+++ V+ + A KII+ K + D+ K L RE + + LKH
Sbjct: 14 YQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQK--LEREARICRLLKHS 71
Query: 445 NLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERG 624
N++R +I Y+V + G L + I ++ E +Q++EAV +CH+ G
Sbjct: 72 NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMG 131
Query: 625 VVHRDIKCENLLMD---HGLNIKLSDFGFA 705
VVHRD+K ENLL+ G +KL+DFG A
Sbjct: 132 VVHRDLKPENLLLASKCKGAAVKLADFGLA 161
>L41816-1|AAA99458.1| 370|Homo sapiens cam kinase I protein.
Length = 370
Score = 83.0 bits (196), Expect = 1e-15
Identities = 48/144 (33%), Positives = 77/144 (53%), Gaps = 3/144 (2%)
Frame = +1
Query: 286 IGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQ 465
+G+G+++ V +A R VAIK I+K G + + EI V+ +KH N++
Sbjct: 26 LGTGAFSEVILAEDKRTQKLVAIKCIAKEALEGK--EGSMENEIAVLHKIKHPNIVALDD 83
Query: 466 AIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIK 645
E+ +Y++M+ G L D I + E R Q+++AV Y H+ G+VHRD+K
Sbjct: 84 IYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGIVHRDLK 143
Query: 646 CENLL---MDHGLNIKLSDFGFAR 708
ENLL +D I +SDFG ++
Sbjct: 144 PENLLYYSLDEDSKIMISDFGLSK 167
>BC106755-1|AAI06756.1| 370|Homo sapiens
calcium/calmodulin-dependent protein kinase I protein.
Length = 370
Score = 83.0 bits (196), Expect = 1e-15
Identities = 48/144 (33%), Positives = 77/144 (53%), Gaps = 3/144 (2%)
Frame = +1
Query: 286 IGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQ 465
+G+G+++ V +A R VAIK I+K G + + EI V+ +KH N++
Sbjct: 26 LGTGAFSEVILAEDKRTQKLVAIKCIAKEALEGK--EGSMENEIAVLHKIKHPNIVALDD 83
Query: 466 AIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIK 645
E+ +Y++M+ G L D I + E R Q+++AV Y H+ G+VHRD+K
Sbjct: 84 IYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGIVHRDLK 143
Query: 646 CENLL---MDHGLNIKLSDFGFAR 708
ENLL +D I +SDFG ++
Sbjct: 144 PENLLYYSLDEDSKIMISDFGLSK 167
>BC106754-1|AAI06755.1| 370|Homo sapiens
calcium/calmodulin-dependent protein kinase I protein.
Length = 370
Score = 83.0 bits (196), Expect = 1e-15
Identities = 48/144 (33%), Positives = 77/144 (53%), Gaps = 3/144 (2%)
Frame = +1
Query: 286 IGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQ 465
+G+G+++ V +A R VAIK I+K G + + EI V+ +KH N++
Sbjct: 26 LGTGAFSEVILAEDKRTQKLVAIKCIAKEALEGK--EGSMENEIAVLHKIKHPNIVALDD 83
Query: 466 AIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIK 645
E+ +Y++M+ G L D I + E R Q+++AV Y H+ G+VHRD+K
Sbjct: 84 IYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGIVHRDLK 143
Query: 646 CENLL---MDHGLNIKLSDFGFAR 708
ENLL +D I +SDFG ++
Sbjct: 144 PENLLYYSLDEDSKIMISDFGLSK 167
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 97,919,388
Number of Sequences: 237096
Number of extensions: 1951185
Number of successful extensions: 8982
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 6776
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7433
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8455186714
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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