Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmte14d24
(614 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U49897-1|AAC51772.1| 452|Homo sapiens phenylalanine hydroxylase... 151 3e-36
K03020-1|AAA60082.1| 452|Homo sapiens phenylalanine hydroxylase... 151 3e-36
BC026251-1|AAH26251.1| 452|Homo sapiens phenylalanine hydroxyla... 151 3e-36
AF404777-1|AAL78816.1| 452|Homo sapiens phenylalanine hydroxyla... 151 3e-36
AY196345-1|AAO72074.1| 206|Homo sapiens tryptophan hydroxylase ... 143 5e-34
X52836-1|CAA37018.1| 444|Homo sapiens protein ( Human mRNA for ... 141 2e-33
BC106739-1|AAI06740.1| 444|Homo sapiens tryptophan hydroxylase ... 141 2e-33
BC114499-1|AAI14500.1| 490|Homo sapiens tryptophan hydroxylase ... 138 1e-32
BC114442-1|AAI14443.1| 496|Homo sapiens TPH2 protein protein. 138 2e-32
AY098914-1|AAM28946.1| 490|Homo sapiens neuronal tryptophan hyd... 138 2e-32
L29306-1|AAA67050.1| 444|Homo sapiens tryptophan hydroxylase pr... 133 4e-31
AK094614-1|BAC04385.1| 250|Homo sapiens protein ( Homo sapiens ... 123 4e-28
BC106740-1|AAI06741.1| 206|Homo sapiens TPH1 protein protein. 122 8e-28
Y00414-1|CAA68472.1| 524|Homo sapiens protein ( Human mRNA for ... 103 4e-22
X05290-1|CAA28908.1| 497|Homo sapiens protein ( Human mRNA for ... 103 4e-22
M17589-1|AAA61179.1| 528|Homo sapiens TH protein. 103 4e-22
DQ677337-1|ABG73365.1| 407|Homo sapiens tyrosine hydroxylase is... 103 4e-22
DQ677336-1|ABG73364.1| 403|Homo sapiens tyrosine hydroxylase is... 103 4e-22
BC104967-1|AAI04968.1| 497|Homo sapiens tyrosine hydroxylase pr... 103 4e-22
AY144495-1|AAN39539.1| 44|Homo sapiens truncated tyrosine hydr... 64 3e-10
AY144494-1|AAN39538.1| 115|Homo sapiens putative tyrosine hydro... 64 3e-10
X90568-1|CAA62188.1|26926|Homo sapiens titin protein. 31 3.2
AJ277892-2|CAD12456.1|30017|Homo sapiens Titin protein. 31 3.2
AJ277892-1|CAD12455.1|26926|Homo sapiens N2B-Titin Isoform protein. 31 3.2
M81601-1|AAA61138.1| 301|Homo sapiens transcription elongation ... 30 7.5
BC105696-1|AAI05697.1| 376|Homo sapiens KLHL30 protein protein. 30 7.5
L06237-1|AAA18904.1| 2468|Homo sapiens microtubule-associated pr... 29 9.9
AK125364-1|BAC86148.1| 298|Homo sapiens protein ( Homo sapiens ... 29 9.9
>U49897-1|AAC51772.1| 452|Homo sapiens phenylalanine hydroxylase
protein.
Length = 452
Score = 151 bits (365), Expect = 3e-36
Identities = 79/161 (49%), Positives = 109/161 (67%), Gaps = 3/161 (1%)
Frame = +2
Query: 137 NYIREGRDSTKSTWLLISPVAPDEAGSLARYLGIFSSHGVNLSHIESRSST-RRPGYEFM 313
+YI + + + L+ S +E G+LA+ L +F + VNL+HIESR S ++ YEF
Sbjct: 23 SYIEDNCNQNGAISLIFS--LKEEVGALAKVLRLFEENDVNLTHIESRPSRLKKDEYEFF 80
Query: 314 VECEHGS-GDFGAALEELKKNVGY-LNIISRNYKDNRSAVPWFPRRIRDLDRFANQILSY 487
+ S ++ L+ ++G ++ +SR+ K + VPWFPR I++LDRFANQILSY
Sbjct: 81 THLDKRSLPALTNIIKILRHDIGATVHELSRDKK--KDTVPWFPRTIQELDRFANQILSY 138
Query: 488 GAELDSDHPGFTDPVYRDRRKYFADIAYNYKHGEPLPYVEY 610
GAELD+DHPGF DPVYR RRK FADIAYNY+HG+P+P VEY
Sbjct: 139 GAELDADHPGFKDPVYRARRKQFADIAYNYRHGQPIPRVEY 179
>K03020-1|AAA60082.1| 452|Homo sapiens phenylalanine hydroxylase
protein.
Length = 452
Score = 151 bits (365), Expect = 3e-36
Identities = 79/161 (49%), Positives = 109/161 (67%), Gaps = 3/161 (1%)
Frame = +2
Query: 137 NYIREGRDSTKSTWLLISPVAPDEAGSLARYLGIFSSHGVNLSHIESRSST-RRPGYEFM 313
+YI + + + L+ S +E G+LA+ L +F + VNL+HIESR S ++ YEF
Sbjct: 23 SYIEDNCNQNGAISLIFS--LKEEVGALAKVLRLFEENDVNLTHIESRPSRLKKDEYEFF 80
Query: 314 VECEHGS-GDFGAALEELKKNVGY-LNIISRNYKDNRSAVPWFPRRIRDLDRFANQILSY 487
+ S ++ L+ ++G ++ +SR+ K + VPWFPR I++LDRFANQILSY
Sbjct: 81 THLDKRSLPALTNIIKILRHDIGATVHELSRDKK--KDTVPWFPRTIQELDRFANQILSY 138
Query: 488 GAELDSDHPGFTDPVYRDRRKYFADIAYNYKHGEPLPYVEY 610
GAELD+DHPGF DPVYR RRK FADIAYNY+HG+P+P VEY
Sbjct: 139 GAELDADHPGFKDPVYRARRKQFADIAYNYRHGQPIPRVEY 179
>BC026251-1|AAH26251.1| 452|Homo sapiens phenylalanine hydroxylase
protein.
Length = 452
Score = 151 bits (365), Expect = 3e-36
Identities = 79/161 (49%), Positives = 109/161 (67%), Gaps = 3/161 (1%)
Frame = +2
Query: 137 NYIREGRDSTKSTWLLISPVAPDEAGSLARYLGIFSSHGVNLSHIESRSST-RRPGYEFM 313
+YI + + + L+ S +E G+LA+ L +F + VNL+HIESR S ++ YEF
Sbjct: 23 SYIEDNCNQNGAISLIFS--LKEEVGALAKVLRLFEENDVNLTHIESRPSRLKKDEYEFF 80
Query: 314 VECEHGS-GDFGAALEELKKNVGY-LNIISRNYKDNRSAVPWFPRRIRDLDRFANQILSY 487
+ S ++ L+ ++G ++ +SR+ K + VPWFPR I++LDRFANQILSY
Sbjct: 81 THLDKRSLPALTNIIKILRHDIGATVHELSRDKK--KDTVPWFPRTIQELDRFANQILSY 138
Query: 488 GAELDSDHPGFTDPVYRDRRKYFADIAYNYKHGEPLPYVEY 610
GAELD+DHPGF DPVYR RRK FADIAYNY+HG+P+P VEY
Sbjct: 139 GAELDADHPGFKDPVYRARRKQFADIAYNYRHGQPIPRVEY 179
>AF404777-1|AAL78816.1| 452|Homo sapiens phenylalanine hydroxylase
protein.
Length = 452
Score = 151 bits (365), Expect = 3e-36
Identities = 79/161 (49%), Positives = 109/161 (67%), Gaps = 3/161 (1%)
Frame = +2
Query: 137 NYIREGRDSTKSTWLLISPVAPDEAGSLARYLGIFSSHGVNLSHIESRSST-RRPGYEFM 313
+YI + + + L+ S +E G+LA+ L +F + VNL+HIESR S ++ YEF
Sbjct: 23 SYIEDNCNQNGAISLIFS--LKEEVGALAKVLRLFEENDVNLTHIESRPSRLKKDEYEFF 80
Query: 314 VECEHGS-GDFGAALEELKKNVGY-LNIISRNYKDNRSAVPWFPRRIRDLDRFANQILSY 487
+ S ++ L+ ++G ++ +SR+ K + VPWFPR I++LDRFANQILSY
Sbjct: 81 THLDKRSLPALTNIIKILRHDIGATVHELSRDKK--KDTVPWFPRTIQELDRFANQILSY 138
Query: 488 GAELDSDHPGFTDPVYRDRRKYFADIAYNYKHGEPLPYVEY 610
GAELD+DHPGF DPVYR RRK FADIAYNY+HG+P+P VEY
Sbjct: 139 GAELDADHPGFKDPVYRARRKQFADIAYNYRHGQPIPRVEY 179
>AY196345-1|AAO72074.1| 206|Homo sapiens tryptophan hydroxylase
protein.
Length = 206
Score = 143 bits (346), Expect = 5e-34
Identities = 70/142 (49%), Positives = 91/142 (64%), Gaps = 5/142 (3%)
Frame = +2
Query: 203 DEAGSLARYLGIFSSHGVNLSHIESRSSTRRPG-YEFMVECEHGSGDFGAALEELKKNVG 379
+E G L + L IF VNL HIESR S RR +E V+C+ L LK +
Sbjct: 24 NEVGGLIKALKIFQEKHVNLLHIESRKSKRRNSEFEIFVDCDINREQLNDILHLLKSHTN 83
Query: 380 YLNI-ISRNY---KDNRSAVPWFPRRIRDLDRFANQILSYGAELDSDHPGFTDPVYRDRR 547
L++ + N+ +D VPWFP++I DLD AN++L YG+ELD+DHPGF D VYR RR
Sbjct: 84 VLSVNLPDNFTLKEDGMETVPWFPKKISDLDHCANRVLMYGSELDADHPGFKDNVYRKRR 143
Query: 548 KYFADIAYNYKHGEPLPYVEYT 613
KYFAD+A NYKHG+P+P VE+T
Sbjct: 144 KYFADLAMNYKHGDPIPKVEFT 165
>X52836-1|CAA37018.1| 444|Homo sapiens protein ( Human mRNA for
tryptophan hydroxylase (EC 1.14.16.4). ).
Length = 444
Score = 141 bits (342), Expect = 2e-33
Identities = 69/142 (48%), Positives = 90/142 (63%), Gaps = 5/142 (3%)
Frame = +2
Query: 203 DEAGSLARYLGIFSSHGVNLSHIESRSSTRRPG-YEFMVECEHGSGDFGAALEELKKNVG 379
+E G L + L IF VNL HIESR S RR +E V+C+ LK +
Sbjct: 26 NEVGGLIKALKIFQEKHVNLLHIESRKSKRRNSEFEIFVDCDINREQLNDIFHLLKSHTN 85
Query: 380 YLNI-ISRNY---KDNRSAVPWFPRRIRDLDRFANQILSYGAELDSDHPGFTDPVYRDRR 547
L++ + N+ +D VPWFP++I DLD AN++L YG+ELD+DHPGF D VYR RR
Sbjct: 86 VLSVNLPDNFTLKEDGMETVPWFPKKISDLDHCANRVLMYGSELDADHPGFKDNVYRKRR 145
Query: 548 KYFADIAYNYKHGEPLPYVEYT 613
KYFAD+A NYKHG+P+P VE+T
Sbjct: 146 KYFADLAMNYKHGDPIPKVEFT 167
>BC106739-1|AAI06740.1| 444|Homo sapiens tryptophan hydroxylase 1
(tryptophan 5-monooxygenase) protein.
Length = 444
Score = 141 bits (342), Expect = 2e-33
Identities = 69/142 (48%), Positives = 90/142 (63%), Gaps = 5/142 (3%)
Frame = +2
Query: 203 DEAGSLARYLGIFSSHGVNLSHIESRSSTRRPG-YEFMVECEHGSGDFGAALEELKKNVG 379
+E G L + L IF VNL HIESR S RR +E V+C+ LK +
Sbjct: 26 NEVGGLIKALKIFQEKHVNLLHIESRKSKRRNSEFEIFVDCDINREQLNDIFHLLKSHTN 85
Query: 380 YLNI-ISRNY---KDNRSAVPWFPRRIRDLDRFANQILSYGAELDSDHPGFTDPVYRDRR 547
L++ + N+ +D VPWFP++I DLD AN++L YG+ELD+DHPGF D VYR RR
Sbjct: 86 VLSVNLPDNFTLKEDGMETVPWFPKKISDLDHCANRVLMYGSELDADHPGFKDNVYRKRR 145
Query: 548 KYFADIAYNYKHGEPLPYVEYT 613
KYFAD+A NYKHG+P+P VE+T
Sbjct: 146 KYFADLAMNYKHGDPIPKVEFT 167
>BC114499-1|AAI14500.1| 490|Homo sapiens tryptophan hydroxylase 2
protein.
Length = 490
Score = 138 bits (335), Expect = 1e-32
Identities = 77/193 (39%), Positives = 110/193 (56%), Gaps = 5/193 (2%)
Frame = +2
Query: 50 EKEMDITAKQIEQPTSGSPPDKPKLMEGGNYIREGRDSTKSTWLLISPVAPDEAGSLARY 229
E+ + + + +P SG DK +G N RE + T ++ S +E G L +
Sbjct: 26 EEHQLLGSSTLNKPNSGKNDDKGN--KGSNK-REAATESGKTAVVFS--LKNEVGGLVKA 80
Query: 230 LGIFSSHGVNLSHIESRSSTRRPG-YEFMVECEHGSGDFGAALEELK--KNVGYLNIISR 400
L +F VN+ HIESR S RR E V+CE G +F ++ LK + LN
Sbjct: 81 LRLFQEKRVNMVHIESRKSRRRSSEVEIFVDCECGKTEFNELIQLLKFQTTIVTLNPPEN 140
Query: 401 NYKDNRSA--VPWFPRRIRDLDRFANQILSYGAELDSDHPGFTDPVYRDRRKYFADIAYN 574
+ + VPWFPR+I +LD+ ++++L YG+ELD+DHPGF D VYR RRKYF D+A
Sbjct: 141 IWTEEEELEDVPWFPRKISELDKCSHRVLMYGSELDADHPGFKDNVYRQRRKYFVDVAMG 200
Query: 575 YKHGEPLPYVEYT 613
YK+G+P+P VEYT
Sbjct: 201 YKYGQPIPRVEYT 213
>BC114442-1|AAI14443.1| 496|Homo sapiens TPH2 protein protein.
Length = 496
Score = 138 bits (333), Expect = 2e-32
Identities = 76/187 (40%), Positives = 107/187 (57%), Gaps = 5/187 (2%)
Frame = +2
Query: 68 TAKQIEQPTSGSPPDKPKLMEGGNYIREGRDSTKSTWLLISPVAPDEAGSLARYLGIFSS 247
T ++ +P SG DK G+ RE + T ++ S +E G L + L +F
Sbjct: 38 TFLKLNKPNSGKNDDKGNK---GSSKREAATESGKTAVVFS--LKNEVGGLVKALRLFQE 92
Query: 248 HGVNLSHIESRSSTRRPG-YEFMVECEHGSGDFGAALEELK--KNVGYLNIISRNYKDNR 418
VN+ HIESR S RR E V+CE G +F ++ LK + LN + +
Sbjct: 93 KRVNMVHIESRKSRRRSSEVEIFVDCECGKTEFNELIQLLKFQTTIVTLNPPENIWTEEE 152
Query: 419 SA--VPWFPRRIRDLDRFANQILSYGAELDSDHPGFTDPVYRDRRKYFADIAYNYKHGEP 592
VPWFPR+I +LD+ ++++L YG+ELD+DHPGF D VYR RRKYF D+A YK+G+P
Sbjct: 153 ELEDVPWFPRKISELDKCSHRVLMYGSELDADHPGFKDNVYRQRRKYFVDVAMGYKYGQP 212
Query: 593 LPYVEYT 613
+P VEYT
Sbjct: 213 IPRVEYT 219
>AY098914-1|AAM28946.1| 490|Homo sapiens neuronal tryptophan
hydroxylase protein.
Length = 490
Score = 138 bits (333), Expect = 2e-32
Identities = 76/193 (39%), Positives = 109/193 (56%), Gaps = 5/193 (2%)
Frame = +2
Query: 50 EKEMDITAKQIEQPTSGSPPDKPKLMEGGNYIREGRDSTKSTWLLISPVAPDEAGSLARY 229
E+ + + + +P SG DK G+ RE + T ++ S +E G L +
Sbjct: 26 EEHQLLGSSTLNKPNSGKNDDKGNK---GSSKREAATESGKTAVVFS--LKNEVGGLVKA 80
Query: 230 LGIFSSHGVNLSHIESRSSTRRPG-YEFMVECEHGSGDFGAALEELK--KNVGYLNIISR 400
L +F VN+ HIESR S RR E V+CE G +F ++ LK + LN
Sbjct: 81 LRLFQEKRVNMVHIESRKSRRRSSEVEIFVDCECGKTEFNELIQLLKFQTTIVTLNPPEN 140
Query: 401 NYKDNRSA--VPWFPRRIRDLDRFANQILSYGAELDSDHPGFTDPVYRDRRKYFADIAYN 574
+ + VPWFPR+I +LD+ ++++L YG+ELD+DHPGF D VYR RRKYF D+A
Sbjct: 141 IWTEEEELEDVPWFPRKISELDKCSHRVLMYGSELDADHPGFKDNVYRQRRKYFVDVAMG 200
Query: 575 YKHGEPLPYVEYT 613
YK+G+P+P VEYT
Sbjct: 201 YKYGQPIPRVEYT 213
>L29306-1|AAA67050.1| 444|Homo sapiens tryptophan hydroxylase
protein.
Length = 444
Score = 133 bits (322), Expect = 4e-31
Identities = 66/142 (46%), Positives = 89/142 (62%), Gaps = 5/142 (3%)
Frame = +2
Query: 203 DEAGSLARYLGIFSSHGVNLSHIESRSSTRRPG-YEFMVECEHGSGDFGAALEELKKNVG 379
+E G L + L IF VNL HIESR S RR +E V+C+ LK +
Sbjct: 26 NEVGGLIKALKIFQEKHVNLLHIESRKSKRRNSEFEIFVDCDTNREQLNDIFHLLKSHTN 85
Query: 380 YLNIISR-NY---KDNRSAVPWFPRRIRDLDRFANQILSYGAELDSDHPGFTDPVYRDRR 547
L++ N+ ++ +VPWFP++I DLD AN++L YG+ELD+DHPGF D VYR RR
Sbjct: 86 VLSVTPPDNFTMKEEGMESVPWFPKKISDLDHCANRVLMYGSELDADHPGFKDNVYRKRR 145
Query: 548 KYFADIAYNYKHGEPLPYVEYT 613
KYFAD A +YK+G+P+P VE+T
Sbjct: 146 KYFADSAMSYKYGDPIPKVEFT 167
>AK094614-1|BAC04385.1| 250|Homo sapiens protein ( Homo sapiens
cDNA FLJ37295 fis, clone BRAMY2015311, moderately
similar to TRYPTOPHAN 5-MONOOXYGENASE (EC 1.14.16.4). ).
Length = 250
Score = 123 bits (297), Expect = 4e-28
Identities = 71/187 (37%), Positives = 102/187 (54%), Gaps = 5/187 (2%)
Frame = +2
Query: 50 EKEMDITAKQIEQPTSGSPPDKPKLMEGGNYIREGRDSTKSTWLLISPVAPDEAGSLARY 229
E+ + + + +P SG DK G+ RE + T ++ S +E G L +
Sbjct: 26 EEHQLLGSSTLNKPNSGKNDDKGNK---GSSKREAATESGKTAVVFS--LKNEVGGLVKA 80
Query: 230 LGIFSSHGVNLSHIESRSSTRRPG-YEFMVECEHGSGDFGAALEELK--KNVGYLNIISR 400
L +F VN+ HIESR S RR E V+CE G +F ++ LK + LN
Sbjct: 81 LRLFQEKRVNMVHIESRKSRRRSSEVEIFVDCECGKTEFNELIQLLKFQTTIVTLNPPEN 140
Query: 401 NYKDNRSA--VPWFPRRIRDLDRFANQILSYGAELDSDHPGFTDPVYRDRRKYFADIAYN 574
+ + VPWFPR+I +LD+ ++++L YG+ELD+DHPGF D VYR RRKYF D+A
Sbjct: 141 IWTEEEELEDVPWFPRKISELDKCSHRVLMYGSELDADHPGFKDNVYRQRRKYFVDVAMG 200
Query: 575 YKHGEPL 595
YK+G L
Sbjct: 201 YKYGPRL 207
>BC106740-1|AAI06741.1| 206|Homo sapiens TPH1 protein protein.
Length = 206
Score = 122 bits (295), Expect = 8e-28
Identities = 62/131 (47%), Positives = 80/131 (61%), Gaps = 5/131 (3%)
Frame = +2
Query: 203 DEAGSLARYLGIFSSHGVNLSHIESRSSTRRPG-YEFMVECEHGSGDFGAALEELKKNVG 379
+E G L + L IF VNL HIESR S RR +E V+C+ LK +
Sbjct: 26 NEVGGLIKALKIFQEKHVNLLHIESRKSKRRNSEFEIFVDCDINREQLNDIFHLLKSHTN 85
Query: 380 YLNI-ISRNY---KDNRSAVPWFPRRIRDLDRFANQILSYGAELDSDHPGFTDPVYRDRR 547
L++ + N+ +D VPWFP++I DLD AN++L YG+ELD+DHPGF D VYR RR
Sbjct: 86 VLSVNLPDNFTLNEDGMETVPWFPKKISDLDHCANRVLMYGSELDADHPGFKDNVYRKRR 145
Query: 548 KYFADIAYNYK 580
KYFAD+A NYK
Sbjct: 146 KYFADLAMNYK 156
>Y00414-1|CAA68472.1| 524|Homo sapiens protein ( Human mRNA for
tyrosine hydroxylase type 3. ).
Length = 524
Score = 103 bits (248), Expect = 4e-22
Identities = 55/150 (36%), Positives = 86/150 (57%), Gaps = 5/150 (3%)
Frame = +2
Query: 179 LLISPVAPDEAGSLARYLGIFSSHGVNLSHIESRSSTRR----PGYEFMVECEHGSGDFG 346
LL SP A + +L+R + +F + + H+E+R + R P E+ V E GD
Sbjct: 111 LLFSPRAT-KPSALSRAVKVFETFEAKIHHLETRPAQRPRAGGPHLEYFVRLEVRRGDLA 169
Query: 347 AALEELKKNVGYLNIISRNYKDNRSA-VPWFPRRIRDLDRFANQILSYGAELDSDHPGFT 523
A L +++ +S + + VPWFPR++ +LD+ + + + +LD DHPGF+
Sbjct: 170 ALLSGVRQ-------VSEDVRSPAGPKVPWFPRKVSELDKCHHLVTKFDPDLDLDHPGFS 222
Query: 524 DPVYRDRRKYFADIAYNYKHGEPLPYVEYT 613
D VYR RRK A+IA+ Y+HG+P+P VEYT
Sbjct: 223 DQVYRQRRKLIAEIAFQYRHGDPIPRVEYT 252
>X05290-1|CAA28908.1| 497|Homo sapiens protein ( Human mRNA for
tyrosine hydroxylase (HTH-1). ).
Length = 497
Score = 103 bits (248), Expect = 4e-22
Identities = 55/150 (36%), Positives = 86/150 (57%), Gaps = 5/150 (3%)
Frame = +2
Query: 179 LLISPVAPDEAGSLARYLGIFSSHGVNLSHIESRSSTRR----PGYEFMVECEHGSGDFG 346
LL SP A + +L+R + +F + + H+E+R + R P E+ V E GD
Sbjct: 84 LLFSPRAT-KPSALSRAVKVFETFEAKIHHLETRPAQRPRAGGPHLEYFVRLEVRRGDLA 142
Query: 347 AALEELKKNVGYLNIISRNYKDNRSA-VPWFPRRIRDLDRFANQILSYGAELDSDHPGFT 523
A L +++ +S + + VPWFPR++ +LD+ + + + +LD DHPGF+
Sbjct: 143 ALLSGVRQ-------VSEDVRSPAGPKVPWFPRKVSELDKCHHLVTKFDPDLDLDHPGFS 195
Query: 524 DPVYRDRRKYFADIAYNYKHGEPLPYVEYT 613
D VYR RRK A+IA+ Y+HG+P+P VEYT
Sbjct: 196 DQVYRQRRKLIAEIAFQYRHGDPIPRVEYT 225
>M17589-1|AAA61179.1| 528|Homo sapiens TH protein.
Length = 528
Score = 103 bits (248), Expect = 4e-22
Identities = 55/150 (36%), Positives = 86/150 (57%), Gaps = 5/150 (3%)
Frame = +2
Query: 179 LLISPVAPDEAGSLARYLGIFSSHGVNLSHIESRSSTRR----PGYEFMVECEHGSGDFG 346
LL SP A + +L+R + +F + + H+E+R + R P E+ V E GD
Sbjct: 115 LLFSPRAT-KPSALSRAVKVFETFEAKIHHLETRPAQRPRAGGPHLEYFVRLEVRRGDLA 173
Query: 347 AALEELKKNVGYLNIISRNYKDNRSA-VPWFPRRIRDLDRFANQILSYGAELDSDHPGFT 523
A L +++ +S + + VPWFPR++ +LD+ + + + +LD DHPGF+
Sbjct: 174 ALLSGVRQ-------VSEDVRSPAGPKVPWFPRKVSELDKCHHLVTKFDPDLDLDHPGFS 226
Query: 524 DPVYRDRRKYFADIAYNYKHGEPLPYVEYT 613
D VYR RRK A+IA+ Y+HG+P+P VEYT
Sbjct: 227 DQVYRQRRKLIAEIAFQYRHGDPIPRVEYT 256
>DQ677337-1|ABG73365.1| 407|Homo sapiens tyrosine hydroxylase
isoform D2,8,9 protein.
Length = 407
Score = 103 bits (248), Expect = 4e-22
Identities = 55/150 (36%), Positives = 86/150 (57%), Gaps = 5/150 (3%)
Frame = +2
Query: 179 LLISPVAPDEAGSLARYLGIFSSHGVNLSHIESRSSTRR----PGYEFMVECEHGSGDFG 346
LL SP A + +L+R + +F + + H+E+R + R P E+ V E GD
Sbjct: 88 LLFSPRAT-KPSALSRAVKVFETFEAKIHHLETRPAQRPRAGGPHLEYFVRLEVRRGDLA 146
Query: 347 AALEELKKNVGYLNIISRNYKDNRSA-VPWFPRRIRDLDRFANQILSYGAELDSDHPGFT 523
A L +++ +S + + VPWFPR++ +LD+ + + + +LD DHPGF+
Sbjct: 147 ALLSGVRQ-------VSEDVRSPAGPKVPWFPRKVSELDKCHHLVTKFDPDLDLDHPGFS 199
Query: 524 DPVYRDRRKYFADIAYNYKHGEPLPYVEYT 613
D VYR RRK A+IA+ Y+HG+P+P VEYT
Sbjct: 200 DQVYRQRRKLIAEIAFQYRHGDPIPRVEYT 229
>DQ677336-1|ABG73364.1| 403|Homo sapiens tyrosine hydroxylase
isoform D1b,2,8,9 protein.
Length = 403
Score = 103 bits (248), Expect = 4e-22
Identities = 55/150 (36%), Positives = 86/150 (57%), Gaps = 5/150 (3%)
Frame = +2
Query: 179 LLISPVAPDEAGSLARYLGIFSSHGVNLSHIESRSSTRR----PGYEFMVECEHGSGDFG 346
LL SP A + +L+R + +F + + H+E+R + R P E+ V E GD
Sbjct: 84 LLFSPRAT-KPSALSRAVKVFETFEAKIHHLETRPAQRPRAGGPHLEYFVRLEVRRGDLA 142
Query: 347 AALEELKKNVGYLNIISRNYKDNRSA-VPWFPRRIRDLDRFANQILSYGAELDSDHPGFT 523
A L +++ +S + + VPWFPR++ +LD+ + + + +LD DHPGF+
Sbjct: 143 ALLSGVRQ-------VSEDVRSPAGPKVPWFPRKVSELDKCHHLVTKFDPDLDLDHPGFS 195
Query: 524 DPVYRDRRKYFADIAYNYKHGEPLPYVEYT 613
D VYR RRK A+IA+ Y+HG+P+P VEYT
Sbjct: 196 DQVYRQRRKLIAEIAFQYRHGDPIPRVEYT 225
>BC104967-1|AAI04968.1| 497|Homo sapiens tyrosine hydroxylase
protein.
Length = 497
Score = 103 bits (248), Expect = 4e-22
Identities = 55/150 (36%), Positives = 86/150 (57%), Gaps = 5/150 (3%)
Frame = +2
Query: 179 LLISPVAPDEAGSLARYLGIFSSHGVNLSHIESRSSTRR----PGYEFMVECEHGSGDFG 346
LL SP A + +L+R + +F + + H+E+R + R P E+ V E GD
Sbjct: 84 LLFSPRAT-KPSALSRAVKVFETFEAKIHHLETRPAQRPRAGGPHLEYFVRLEVRRGDLA 142
Query: 347 AALEELKKNVGYLNIISRNYKDNRSA-VPWFPRRIRDLDRFANQILSYGAELDSDHPGFT 523
A L +++ +S + + VPWFPR++ +LD+ + + + +LD DHPGF+
Sbjct: 143 ALLSGVRQ-------VSEDVRSPAGPKVPWFPRKVSELDKCHHLVTKFDPDLDLDHPGFS 195
Query: 524 DPVYRDRRKYFADIAYNYKHGEPLPYVEYT 613
D VYR RRK A+IA+ Y+HG+P+P VEYT
Sbjct: 196 DQVYRQRRKLIAEIAFQYRHGDPIPRVEYT 225
>AY144495-1|AAN39539.1| 44|Homo sapiens truncated tyrosine
hydroxylase protein.
Length = 44
Score = 64.5 bits (150), Expect = 3e-10
Identities = 25/38 (65%), Positives = 31/38 (81%)
Frame = +2
Query: 500 DSDHPGFTDPVYRDRRKYFADIAYNYKHGEPLPYVEYT 613
D DHPGF+D VYR RRK A+IA+ Y+HG+P+P VEYT
Sbjct: 1 DLDHPGFSDQVYRQRRKLIAEIAFQYRHGDPIPRVEYT 38
>AY144494-1|AAN39538.1| 115|Homo sapiens putative tyrosine
hydroxylase variant protein.
Length = 115
Score = 64.5 bits (150), Expect = 3e-10
Identities = 25/38 (65%), Positives = 31/38 (81%)
Frame = +2
Query: 500 DSDHPGFTDPVYRDRRKYFADIAYNYKHGEPLPYVEYT 613
D DHPGF+D VYR RRK A+IA+ Y+HG+P+P VEYT
Sbjct: 1 DLDHPGFSDQVYRQRRKLIAEIAFQYRHGDPIPRVEYT 38
>X90568-1|CAA62188.1|26926|Homo sapiens titin protein.
Length = 26926
Score = 31.1 bits (67), Expect = 3.2
Identities = 14/29 (48%), Positives = 20/29 (68%), Gaps = 4/29 (13%)
Frame = +2
Query: 116 PKLMEGG----NYIREGRDSTKSTWLLIS 190
P L++GG NY+ E RD+TK TW ++S
Sbjct: 20891 PPLIDGGSPIINYVIEKRDATKRTWSVVS 20919
>AJ277892-2|CAD12456.1|30017|Homo sapiens Titin protein.
Length = 30000
Score = 31.1 bits (67), Expect = 3.2
Identities = 14/29 (48%), Positives = 20/29 (68%), Gaps = 4/29 (13%)
Frame = +2
Query: 116 PKLMEGG----NYIREGRDSTKSTWLLIS 190
P L++GG NY+ E RD+TK TW ++S
Sbjct: 28315 PPLIDGGSPIINYVIEKRDATKRTWSVVS 28343
>AJ277892-1|CAD12455.1|26926|Homo sapiens N2B-Titin Isoform protein.
Length = 26926
Score = 31.1 bits (67), Expect = 3.2
Identities = 14/29 (48%), Positives = 20/29 (68%), Gaps = 4/29 (13%)
Frame = +2
Query: 116 PKLMEGG----NYIREGRDSTKSTWLLIS 190
P L++GG NY+ E RD+TK TW ++S
Sbjct: 20891 PPLIDGGSPIINYVIEKRDATKRTWSVVS 20919
>M81601-1|AAA61138.1| 301|Homo sapiens transcription elongation
factor SII protein.
Length = 301
Score = 29.9 bits (64), Expect = 7.5
Identities = 17/61 (27%), Positives = 30/61 (49%), Gaps = 1/61 (1%)
Frame = +2
Query: 41 PATEKEMDITAKQIEQPTSGSPPDKPKLMEGGNYI-REGRDSTKSTWLLISPVAPDEAGS 217
P+TEK++D K+ + SP + + GN R+ + + T+L P AP + S
Sbjct: 80 PSTEKDLDEKKKEPAITSQNSPEAREESTSSGNVSNRKDETNARDTYLSSFPRAPSTSDS 139
Query: 218 L 220
+
Sbjct: 140 V 140
>BC105696-1|AAI05697.1| 376|Homo sapiens KLHL30 protein protein.
Length = 376
Score = 29.9 bits (64), Expect = 7.5
Identities = 15/36 (41%), Positives = 21/36 (58%)
Frame = -1
Query: 221 LTSQPRRVRLVKSEAKLIW*NHDPRGCSCHLPSILA 114
L QP + RL EA + W HDP+ + HLP +L+
Sbjct: 170 LQVQPEQSRL---EALMRWVRHDPQARAVHLPELLS 202
>L06237-1|AAA18904.1| 2468|Homo sapiens microtubule-associated protein
1B protein.
Length = 2468
Score = 29.5 bits (63), Expect = 9.9
Identities = 22/89 (24%), Positives = 37/89 (41%), Gaps = 3/89 (3%)
Frame = +2
Query: 32 TPLPATEKEMDITAKQIEQPTSGSPPD-KPKLMEGGNYIREGRDSTKSTWLLISPVAPDE 208
TP E EM + ++ +P S SPPD PK + +++ R S + +P++
Sbjct: 1597 TPTTFQETEMSPSKEECPRPMSISPPDFSPKTAKSRTPVQDHRSEQSSMSIEFGQESPEQ 1656
Query: 209 --AGSLARYLGIFSSHGVNLSHIESRSST 289
A +R + G + HI T
Sbjct: 1657 SLAMDFSRQSPDHPTVGAGVLHITENGPT 1685
>AK125364-1|BAC86148.1| 298|Homo sapiens protein ( Homo sapiens
cDNA FLJ43374 fis, clone NTONG2007517, weakly similar
to RING CANAL PROTEIN. ).
Length = 298
Score = 29.5 bits (63), Expect = 9.9
Identities = 15/36 (41%), Positives = 21/36 (58%)
Frame = -1
Query: 221 LTSQPRRVRLVKSEAKLIW*NHDPRGCSCHLPSILA 114
L QP + RL EA + W HDP+ + HLP +L+
Sbjct: 170 LQVQPEQGRL---EALMRWVRHDPQARAVHLPELLS 202
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 103,179,001
Number of Sequences: 237096
Number of extensions: 2451028
Number of successful extensions: 6748
Number of sequences better than 10.0: 28
Number of HSP's better than 10.0 without gapping: 6306
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6733
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 6579110070
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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