Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmte14a17
(706 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
CR541695-1|CAG46496.1| 414|Homo sapiens IDH1 protein. 333 3e-91
BC093020-1|AAH93020.1| 414|Homo sapiens isocitrate dehydrogenas... 333 3e-91
BC012846-1|AAH12846.1| 414|Homo sapiens IDH1 protein protein. 333 3e-91
AF113917-1|AAD29284.1| 414|Homo sapiens NADP+-dependent isocitr... 333 3e-91
AF020038-1|AAD02918.1| 414|Homo sapiens NADP-dependent isocitra... 333 3e-91
AC016697-3|AAX93221.1| 414|Homo sapiens unknown protein. 333 3e-91
CR533522-1|CAG38553.1| 414|Homo sapiens IDH1 protein. 332 5e-91
CR536499-1|CAG38738.1| 414|Homo sapiens IDH1 protein. 332 7e-91
BX537411-1|CAD97653.1| 414|Homo sapiens hypothetical protein pr... 331 1e-90
X69433-1|CAA49208.1| 452|Homo sapiens isocitrate dehydrogenase... 316 7e-86
BC071828-1|AAH71828.1| 452|Homo sapiens isocitrate dehydrogenas... 315 9e-86
BC009244-1|AAH09244.1| 452|Homo sapiens isocitrate dehydrogenas... 315 9e-86
AK222916-1|BAD96636.1| 452|Homo sapiens isocitrate dehydrogenas... 315 9e-86
DQ403082-1|ABD77215.1| 371|Homo sapiens isocitrate dehydrogenas... 293 3e-79
U52144-1|AAC50455.1| 419|Homo sapiens isocitrate dehydrogenase ... 268 1e-71
U62389-1|AAB17375.1| 154|Homo sapiens putative cytosolic NADP-d... 168 1e-41
BC020198-1|AAH20198.1| 567|Homo sapiens MEGF10 protein protein. 30 7.0
AB058676-1|BAB47409.1| 1140|Homo sapiens MEGF10 protein (KIAA178... 30 7.0
>CR541695-1|CAG46496.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 333 bits (819), Expect = 3e-91
Identities = 154/213 (72%), Positives = 183/213 (85%), Gaps = 2/213 (0%)
Frame = +3
Query: 72 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 251
KI G VV++ GDEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 252 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 431
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 432 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMF 605
W KPIIIGRHA+ DQY+ATDFVVPG G +EI + P G + + ++VH + +G GVA+ M+
Sbjct: 124 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMY 183
Query: 606 NTDASIIDFAHSSFKFALDRKYPLYLSTKNTIL 704
N D SI DFAHSSF+ AL + +PLYLSTKNTIL
Sbjct: 184 NQDKSIEDFAHSSFQMALSKGWPLYLSTKNTIL 216
>BC093020-1|AAH93020.1| 414|Homo sapiens isocitrate dehydrogenase 1
(NADP+), soluble protein.
Length = 414
Score = 333 bits (819), Expect = 3e-91
Identities = 154/213 (72%), Positives = 183/213 (85%), Gaps = 2/213 (0%)
Frame = +3
Query: 72 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 251
KI G VV++ GDEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 252 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 431
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 432 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMF 605
W KPIIIGRHA+ DQY+ATDFVVPG G +EI + P G + + ++VH + +G GVA+ M+
Sbjct: 124 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMY 183
Query: 606 NTDASIIDFAHSSFKFALDRKYPLYLSTKNTIL 704
N D SI DFAHSSF+ AL + +PLYLSTKNTIL
Sbjct: 184 NQDKSIEDFAHSSFQMALSKGWPLYLSTKNTIL 216
>BC012846-1|AAH12846.1| 414|Homo sapiens IDH1 protein protein.
Length = 414
Score = 333 bits (819), Expect = 3e-91
Identities = 154/213 (72%), Positives = 183/213 (85%), Gaps = 2/213 (0%)
Frame = +3
Query: 72 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 251
KI G VV++ GDEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 252 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 431
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 432 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMF 605
W KPIIIGRHA+ DQY+ATDFVVPG G +EI + P G + + ++VH + +G GVA+ M+
Sbjct: 124 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMY 183
Query: 606 NTDASIIDFAHSSFKFALDRKYPLYLSTKNTIL 704
N D SI DFAHSSF+ AL + +PLYLSTKNTIL
Sbjct: 184 NQDKSIEDFAHSSFQMALSKGWPLYLSTKNTIL 216
>AF113917-1|AAD29284.1| 414|Homo sapiens NADP+-dependent isocitrate
dehydrogenase protein.
Length = 414
Score = 333 bits (819), Expect = 3e-91
Identities = 154/213 (72%), Positives = 183/213 (85%), Gaps = 2/213 (0%)
Frame = +3
Query: 72 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 251
KI G VV++ GDEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 252 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 431
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 432 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMF 605
W KPIIIGRHA+ DQY+ATDFVVPG G +EI + P G + + ++VH + +G GVA+ M+
Sbjct: 124 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMY 183
Query: 606 NTDASIIDFAHSSFKFALDRKYPLYLSTKNTIL 704
N D SI DFAHSSF+ AL + +PLYLSTKNTIL
Sbjct: 184 NQDKSIEDFAHSSFQMALSKGWPLYLSTKNTIL 216
>AF020038-1|AAD02918.1| 414|Homo sapiens NADP-dependent isocitrate
dehydrogenase protein.
Length = 414
Score = 333 bits (819), Expect = 3e-91
Identities = 154/213 (72%), Positives = 183/213 (85%), Gaps = 2/213 (0%)
Frame = +3
Query: 72 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 251
KI G VV++ GDEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 252 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 431
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 432 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMF 605
W KPIIIGRHA+ DQY+ATDFVVPG G +EI + P G + + ++VH + +G GVA+ M+
Sbjct: 124 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMY 183
Query: 606 NTDASIIDFAHSSFKFALDRKYPLYLSTKNTIL 704
N D SI DFAHSSF+ AL + +PLYLSTKNTIL
Sbjct: 184 NQDKSIEDFAHSSFQMALSKGWPLYLSTKNTIL 216
>AC016697-3|AAX93221.1| 414|Homo sapiens unknown protein.
Length = 414
Score = 333 bits (819), Expect = 3e-91
Identities = 154/213 (72%), Positives = 183/213 (85%), Gaps = 2/213 (0%)
Frame = +3
Query: 72 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 251
KI G VV++ GDEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 252 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 431
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 432 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMF 605
W KPIIIGRHA+ DQY+ATDFVVPG G +EI + P G + + ++VH + +G GVA+ M+
Sbjct: 124 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMY 183
Query: 606 NTDASIIDFAHSSFKFALDRKYPLYLSTKNTIL 704
N D SI DFAHSSF+ AL + +PLYLSTKNTIL
Sbjct: 184 NQDKSIEDFAHSSFQMALSKGWPLYLSTKNTIL 216
>CR533522-1|CAG38553.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 332 bits (817), Expect = 5e-91
Identities = 153/213 (71%), Positives = 184/213 (86%), Gaps = 2/213 (0%)
Frame = +3
Query: 72 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 251
KI G VV++ GDEMTRIIW+LIKEKLI+P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIIPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 252 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 431
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 432 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMF 605
W +PIIIGRHA+ DQY+ATDFVVPG G +EI + P G + + ++VH + +G GVA+ M+
Sbjct: 124 WVEPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMY 183
Query: 606 NTDASIIDFAHSSFKFALDRKYPLYLSTKNTIL 704
N D SI DFAHSSF+ AL + +PLYLSTKNTIL
Sbjct: 184 NQDKSIEDFAHSSFQMALSKGWPLYLSTKNTIL 216
>CR536499-1|CAG38738.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 332 bits (816), Expect = 7e-91
Identities = 153/213 (71%), Positives = 183/213 (85%), Gaps = 2/213 (0%)
Frame = +3
Query: 72 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 251
KI G VV++ GDEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 252 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 431
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 432 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMF 605
W KPIIIGRHA+ DQY+ATDFVVPG G +E+ + P G + + ++VH + +G GVA+ M+
Sbjct: 124 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEMTYTPSDGTQKVTYLVHNFEEGGGVAMGMY 183
Query: 606 NTDASIIDFAHSSFKFALDRKYPLYLSTKNTIL 704
N D SI DFAHSSF+ AL + +PLYLSTKNTIL
Sbjct: 184 NQDKSIEDFAHSSFQMALSKGWPLYLSTKNTIL 216
>BX537411-1|CAD97653.1| 414|Homo sapiens hypothetical protein
protein.
Length = 414
Score = 331 bits (814), Expect = 1e-90
Identities = 154/213 (72%), Positives = 182/213 (85%), Gaps = 2/213 (0%)
Frame = +3
Query: 72 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 251
KI G VV++ GDEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 252 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 431
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 432 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEYK-GAGVALAMF 605
W KPIIIGRHA+ DQY+ATDFVVPG G +EI + P G + + ++VH + G GVA+ M+
Sbjct: 124 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNSEGGGGVAMGMY 183
Query: 606 NTDASIIDFAHSSFKFALDRKYPLYLSTKNTIL 704
N D SI DFAHSSF+ AL + +PLYLSTKNTIL
Sbjct: 184 NQDKSIEDFAHSSFQMALSKGWPLYLSTKNTIL 216
>X69433-1|CAA49208.1| 452|Homo sapiens isocitrate dehydrogenase
(NADP+) protein.
Length = 452
Score = 316 bits (775), Expect = 7e-86
Identities = 148/222 (66%), Positives = 175/222 (78%), Gaps = 2/222 (0%)
Frame = +3
Query: 45 YSRHRYNMSKIK-AGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTD 221
+ R Y +IK A PVV++ GDEMTRIIW IKEKLILP +DI+L +DLG+ NRD+TD
Sbjct: 34 HPRRHYADKRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTD 93
Query: 222 DQVTIDCAEAIKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAII 401
DQVTID A A +KY+V +KCATITPDE RVEEFKLKKMWKSPNGTIRNILGGTVFRE II
Sbjct: 94 DQVTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPII 153
Query: 402 CKNIPRLVTGWDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESGEAIKH-VVHEYK 578
CKNIPRLV GW KPI IGRHAH DQYKATDFV AGT +++F P+ G +K V+ +
Sbjct: 154 CKNIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFP 213
Query: 579 GAGVALAMFNTDASIIDFAHSSFKFALDRKYPLYLSTKNTIL 704
GV + M+NTD SI FAHS F++A+ +K+PLY+STKNTIL
Sbjct: 214 AGGVGMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTIL 255
>BC071828-1|AAH71828.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial protein.
Length = 452
Score = 315 bits (774), Expect = 9e-86
Identities = 148/220 (67%), Positives = 174/220 (79%), Gaps = 2/220 (0%)
Frame = +3
Query: 51 RHRYNMSKIK-AGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQ 227
R Y +IK A PVV++ GDEMTRIIW IKEKLILP +DI+L +DLG+ NRD+TDDQ
Sbjct: 36 RRHYADKRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQ 95
Query: 228 VTIDCAEAIKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICK 407
VTID A A +KY+V +KCATITPDE RVEEFKLKKMWKSPNGTIRNILGGTVFRE IICK
Sbjct: 96 VTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICK 155
Query: 408 NIPRLVTGWDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESGEAIKH-VVHEYKGA 584
NIPRLV GW KPI IGRHAH DQYKATDFV AGT +++F P+ G +K V+ +
Sbjct: 156 NIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAG 215
Query: 585 GVALAMFNTDASIIDFAHSSFKFALDRKYPLYLSTKNTIL 704
GV + M+NTD SI FAHS F++A+ +K+PLY+STKNTIL
Sbjct: 216 GVGMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTIL 255
>BC009244-1|AAH09244.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial protein.
Length = 452
Score = 315 bits (774), Expect = 9e-86
Identities = 148/220 (67%), Positives = 174/220 (79%), Gaps = 2/220 (0%)
Frame = +3
Query: 51 RHRYNMSKIK-AGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQ 227
R Y +IK A PVV++ GDEMTRIIW IKEKLILP +DI+L +DLG+ NRD+TDDQ
Sbjct: 36 RRHYADKRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQ 95
Query: 228 VTIDCAEAIKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICK 407
VTID A A +KY+V +KCATITPDE RVEEFKLKKMWKSPNGTIRNILGGTVFRE IICK
Sbjct: 96 VTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICK 155
Query: 408 NIPRLVTGWDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESGEAIKH-VVHEYKGA 584
NIPRLV GW KPI IGRHAH DQYKATDFV AGT +++F P+ G +K V+ +
Sbjct: 156 NIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAG 215
Query: 585 GVALAMFNTDASIIDFAHSSFKFALDRKYPLYLSTKNTIL 704
GV + M+NTD SI FAHS F++A+ +K+PLY+STKNTIL
Sbjct: 216 GVGMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTIL 255
>AK222916-1|BAD96636.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial precursor variant protein.
Length = 452
Score = 315 bits (774), Expect = 9e-86
Identities = 148/220 (67%), Positives = 174/220 (79%), Gaps = 2/220 (0%)
Frame = +3
Query: 51 RHRYNMSKIK-AGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQ 227
R Y +IK A PVV++ GDEMTRIIW IKEKLILP +DI+L +DLG+ NRD+TDDQ
Sbjct: 36 RRHYADKRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQ 95
Query: 228 VTIDCAEAIKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICK 407
VTID A A +KY+V +KCATITPDE RVEEFKLKKMWKSPNGTIRNILGGTVFRE IICK
Sbjct: 96 VTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICK 155
Query: 408 NIPRLVTGWDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESGEAIKH-VVHEYKGA 584
NIPRLV GW KPI IGRHAH DQYKATDFV AGT +++F P+ G +K V+ +
Sbjct: 156 NIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAG 215
Query: 585 GVALAMFNTDASIIDFAHSSFKFALDRKYPLYLSTKNTIL 704
GV + M+NTD SI FAHS F++A+ +K+PLY+STKNTIL
Sbjct: 216 GVGMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTIL 255
>DQ403082-1|ABD77215.1| 371|Homo sapiens isocitrate dehydrogenase 1
protein.
Length = 371
Score = 293 bits (720), Expect = 3e-79
Identities = 135/187 (72%), Positives = 161/187 (86%), Gaps = 2/187 (1%)
Frame = +3
Query: 150 LILPFLDIELHVYDLGMENRDKTDDQVTIDCAEAIKKYNVGIKCATITPDEKRVEEFKLK 329
LI P+++++LH YDLG+ENRD T+DQVT D AEAIKK+NVG+KCATITPDEKRVEEFKLK
Sbjct: 1 LIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLK 60
Query: 330 KMWKSPNGTIRNILGGTVFREAIICKNIPRLVTGWDKPIIIGRHAHADQYKATDFVVPGA 509
+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+GW KPIIIGRHA+ DQY+ATDFVVPG
Sbjct: 61 QMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGP 120
Query: 510 GTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMFNTDASIIDFAHSSFKFALDRKYPLYL 683
G +EI + P G + + ++VH + +G GVA+ M+N D SI DFAHSSF+ AL + +PLYL
Sbjct: 121 GKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYL 180
Query: 684 STKNTIL 704
STKNTIL
Sbjct: 181 STKNTIL 187
>U52144-1|AAC50455.1| 419|Homo sapiens isocitrate dehydrogenase
protein.
Length = 419
Score = 268 bits (658), Expect = 1e-71
Identities = 122/181 (67%), Positives = 145/181 (80%), Gaps = 1/181 (0%)
Frame = +3
Query: 165 LDIELHVYDLGMENRDKTDDQVTIDCAEAIKKYNVGIKCATITPDEKRVEEFKLKKMWKS 344
LD++L +DLG+ NRD+TDDQVTID A A +KY+V +KCATITPDE RVEEFKLKKMWKS
Sbjct: 42 LDVQLKYFDLGLPNRDQTDDQVTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKS 101
Query: 345 PNGTIRNILGGTVFREAIICKNIPRLVTGWDKPIIIGRHAHADQYKATDFVVPGAGTLEI 524
PNGTIRNI GGTVFRE IICKNIPRLV GW KPI IGRHAH DQYKATDFV AGT ++
Sbjct: 102 PNGTIRNIHGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKM 161
Query: 525 IFKPESGEAIKH-VVHEYKGAGVALAMFNTDASIIDFAHSSFKFALDRKYPLYLSTKNTI 701
+F P+ G +K V+ + GV + M+NTD SI FAHS F++A+ +K+PLY+STKNTI
Sbjct: 162 VFTPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTI 221
Query: 702 L 704
L
Sbjct: 222 L 222
>U62389-1|AAB17375.1| 154|Homo sapiens putative cytosolic
NADP-dependent isocitrate dehydrogenase protein.
Length = 154
Score = 168 bits (409), Expect = 1e-41
Identities = 79/117 (67%), Positives = 95/117 (81%), Gaps = 2/117 (1%)
Frame = +3
Query: 360 RNILGGTVFREAIICKNIPRLVTGWDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPE 539
RNILGGTVF EAIICKNIPRLV+GW KPIIIGRHA+ DQY+ATDFVVPG G +EI + P
Sbjct: 1 RNILGGTVFXEAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPS 60
Query: 540 SG-EAIKHVVHEY-KGAGVALAMFNTDASIIDFAHSSFKFALDRKYPLYLSTKNTIL 704
G + + ++VH + +G GVA+ M+N D SI DFAHSSF+ AL + +PLYLSTKNTIL
Sbjct: 61 DGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTIL 117
>BC020198-1|AAH20198.1| 567|Homo sapiens MEGF10 protein protein.
Length = 567
Score = 30.3 bits (65), Expect = 7.0
Identities = 21/68 (30%), Positives = 24/68 (35%), Gaps = 3/68 (4%)
Frame = +2
Query: 422 CNRVGQTHHHWTSCSC*SIQSN*LC---CPRCWYS*NNLQT*IW*GNKTCSS*VQGCRCS 592
C G HH CSC S +C CP + N Q TC + C CS
Sbjct: 240 CQNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCS 299
Query: 593 TGYV*H*C 616
GY C
Sbjct: 300 PGYTGERC 307
>AB058676-1|BAB47409.1| 1140|Homo sapiens MEGF10 protein (KIAA1780)
protein.
Length = 1140
Score = 30.3 bits (65), Expect = 7.0
Identities = 21/68 (30%), Positives = 24/68 (35%), Gaps = 3/68 (4%)
Frame = +2
Query: 422 CNRVGQTHHHWTSCSC*SIQSN*LC---CPRCWYS*NNLQT*IW*GNKTCSS*VQGCRCS 592
C G HH CSC S +C CP + N Q TC + C CS
Sbjct: 240 CQNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCS 299
Query: 593 TGYV*H*C 616
GY C
Sbjct: 300 PGYTGERC 307
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 102,893,234
Number of Sequences: 237096
Number of extensions: 2317615
Number of successful extensions: 4131
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 3964
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4109
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8175213644
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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