Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmte10m17
(738 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxystero... 157 5e-38
U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol dehyd... 154 3e-37
U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase... 154 3e-37
M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase... 154 3e-37
BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase fam... 154 3e-37
BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase fam... 154 3e-37
BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase fam... 154 3e-37
BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase fam... 154 3e-37
AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase fam... 154 3e-37
AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid ... 154 3e-37
AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid... 154 3e-37
AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid ... 153 5e-37
AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid d... 153 5e-37
S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase pro... 153 6e-37
D26125-1|BAA05122.1| 321|Homo sapiens 3 alpha-hydroxysteroid/di... 153 6e-37
AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase fam... 153 6e-37
AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogena... 153 6e-37
AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogena... 153 6e-37
D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein. 153 8e-37
CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein. 153 8e-37
BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase fam... 153 8e-37
AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthas... 153 8e-37
AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein. 153 8e-37
J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein. 152 1e-36
BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase fam... 152 1e-36
BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase fam... 152 1e-36
BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase fam... 152 1e-36
AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase fam... 152 1e-36
S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase hom... 152 1e-36
S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase hom... 152 1e-36
X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for ... 151 2e-36
M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein. 151 2e-36
M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose re... 151 2e-36
L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid de... 151 2e-36
J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein. 151 2e-36
J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein. 151 2e-36
CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein. 151 2e-36
BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase fam... 151 2e-36
BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase fam... 151 2e-36
BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase fam... 151 2e-36
AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen HD-C... 151 2e-36
AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein. 151 2e-36
U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase... 151 3e-36
S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase hom... 151 3e-36
L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol dehydrogenase... 151 3e-36
BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase fam... 151 3e-36
BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase fam... 151 3e-36
BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase fam... 151 3e-36
AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase fam... 151 3e-36
AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase fam... 151 3e-36
AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase fam... 151 3e-36
AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding prote... 151 3e-36
AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding prote... 151 3e-36
AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding p... 151 3e-36
J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein. 150 6e-36
CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein. 150 6e-36
BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase fam... 150 6e-36
BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase fam... 150 6e-36
BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase fam... 150 6e-36
AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase fam... 150 6e-36
AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase prot... 150 6e-36
AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase prot... 150 6e-36
AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase fam... 148 2e-35
BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase fam... 146 1e-34
D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase... 145 2e-34
M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordeco... 142 2e-33
Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5 be... 135 2e-31
BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase fam... 135 2e-31
BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase fam... 135 2e-31
AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductas... 135 2e-31
U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like pep... 131 3e-30
CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein. 131 3e-30
BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase fam... 131 3e-30
BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase fam... 131 3e-30
AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase pro... 131 3e-30
AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase prot... 126 6e-29
AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase loo... 72 5e-27
BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein. 72 5e-27
AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase rel... 72 5e-27
AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase fam... 113 8e-25
AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase rel... 72 2e-21
AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase rel... 72 2e-21
AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase fam... 88 3e-17
AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto red... 84 6e-16
AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase fam... 81 4e-15
AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase fam... 81 4e-15
AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase rel... 72 2e-12
AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens ... 68 3e-11
BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase fam... 67 5e-11
BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase fam... 67 5e-11
AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens ... 67 5e-11
AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthas... 57 8e-08
U16953-1|AAC50122.1| 408|Homo sapiens potassium channel beta3 s... 46 1e-04
L39833-1|AAC37573.1| 408|Homo sapiens K+ channel beta-subunit p... 46 1e-04
X83127-1|CAA58208.1| 401|Homo sapiens voltage gated potassium c... 46 2e-04
U33428-1|AAC50953.1| 401|Homo sapiens K+ channel beta 1a subuni... 46 2e-04
L47665-1|AAC41926.1| 419|Homo sapiens K+ channel beta-subunit p... 46 2e-04
BC043166-1|AAH43166.1| 401|Homo sapiens potassium voltage-gated... 46 2e-04
AF026947-1|AAC52104.1| 330|Homo sapiens aflatoxin aldehyde redu... 41 0.005
Y16675-1|CAA76347.1| 330|Homo sapiens aflatoxin B1-aldehyde red... 40 0.009
BT007347-1|AAP36011.1| 330|Homo sapiens aldo-keto reductase fam... 40 0.009
BC013996-1|AAH13996.1| 330|Homo sapiens AKR7A2 protein protein. 40 0.009
BC012171-1|AAH12171.1| 330|Homo sapiens AKR7A2 protein protein. 40 0.009
BC011586-1|AAH11586.1| 330|Homo sapiens AKR7A2 protein protein. 40 0.009
BC010852-1|AAH10852.1| 330|Homo sapiens AKR7A2 protein protein. 40 0.009
BC007352-1|AAH07352.2| 358|Homo sapiens AKR7A2 protein protein. 40 0.009
BC004111-1|AAH04111.3| 330|Homo sapiens AKR7A2 protein protein. 40 0.009
AL035413-8|CAB72321.1| 330|Homo sapiens aldo-keto reductase fam... 40 0.009
AB037905-2|BAA92890.1| 45|Homo sapiens truncated aldo-keto red... 39 0.022
BC042420-1|AAH42420.2| 331|Homo sapiens aldo-keto reductase fam... 37 0.087
BC031562-1|AAH31562.1| 331|Homo sapiens aldo-keto reductase fam... 37 0.087
AY780786-1|AAV98356.1| 372|Homo sapiens potassium voltage-gated... 37 0.087
AJ271799-1|CAC81076.1| 331|Homo sapiens aflatoxin B1 aldehyde r... 37 0.087
AF040639-1|AAD02195.1| 331|Homo sapiens aflatoxin B1-aldehyde r... 37 0.087
BC025709-1|AAH25709.1| 331|Homo sapiens aldo-keto reductase fam... 36 0.11
AL035413-11|CAI22232.1| 331|Homo sapiens aldo-keto reductase fa... 36 0.11
AJ278012-1|CAC79668.1| 259|Homo sapiens aflatoxin B1 aldehyde r... 33 0.81
Y13790-1|CAA74116.1| 123|Homo sapiens immunoglobulin heavy chai... 33 1.4
BX537840-1|CAD97851.1| 2150|Homo sapiens hypothetical protein pr... 32 1.9
BC040523-1|AAH40523.1| 1551|Homo sapiens CCR4-NOT transcription ... 32 1.9
BC024317-1|AAH24317.1| 1620|Homo sapiens CNOT1 protein protein. 32 1.9
AB067375-1|BAC02410.1| 121|Homo sapiens immunoglobulin heavy ch... 32 1.9
AB063668-1|BAC01296.1| 119|Homo sapiens immunoglobulin heavy ch... 32 1.9
AB023224-1|BAA76851.2| 1835|Homo sapiens KIAA1007 protein protein. 32 1.9
AM079206-1|CAL03352.1| 101|Homo sapiens immunoglobulin heavy ch... 32 2.5
DQ926255-1|ABK81474.1| 122|Homo sapiens immunoglobulin heavy ch... 31 5.7
AJ555274-1|CAD87759.1| 118|Homo sapiens immunoglobulin heavy ch... 30 7.5
AF471315-1|AAQ05490.1| 128|Homo sapiens Ig heavy chain variable... 30 7.5
U17968-1|AAC50113.1| 133|Homo sapiens voltage-gated potassium c... 30 10.0
AM082400-1|CAL06546.1| 101|Homo sapiens immunoglobulin heavy ch... 30 10.0
AM079381-1|CAL03527.1| 100|Homo sapiens immunoglobulin heavy ch... 30 10.0
AB066933-1|BAC01971.1| 129|Homo sapiens immunoglobulin heavy ch... 30 10.0
>DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 157 bits (380), Expect = 5e-38
Identities = 93/219 (42%), Positives = 134/219 (61%), Gaps = 18/219 (8%)
Frame = +1
Query: 97 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 276
+ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY NE+Q+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQV 61
Query: 277 GAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHNPVA 438
G AVR+ + REDIF +KL ++ R ++V+ LE+SL + + YVDLYLIH+P++
Sbjct: 62 GLAVRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKKAQLDYVDLYLIHSPMS 121
Query: 439 FNPGFK-------G---FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG- 585
PG + G FDIVD TW+ ME+ K+ GLAKSIG+SNFN Q++ IL
Sbjct: 122 LKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
Query: 586 -QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFG 699
+ KP QVE + + + KL+D+CK IV++A+S G
Sbjct: 182 LKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALG 220
>U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol
dehydrogenase protein.
Length = 323
Score = 154 bits (374), Expect = 3e-37
Identities = 95/232 (40%), Positives = 136/232 (58%), Gaps = 18/232 (7%)
Frame = +1
Query: 97 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 276
+ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY NE+Q+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQV 61
Query: 277 GAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHNPVA 438
G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH PV+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 439 FNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG- 585
PG + FD VD TW+ +E+ K+ GLAKSIG+SNFN Q++ IL
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
Query: 586 -QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFGPMFHDSLPSIRPD 738
+ KP QVE + + Q KL+D+CK IV++A+S G H P + P+
Sbjct: 182 LKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS--HREEPWVDPN 231
>U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 154 bits (374), Expect = 3e-37
Identities = 95/232 (40%), Positives = 136/232 (58%), Gaps = 18/232 (7%)
Frame = +1
Query: 97 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 276
+ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY NE+Q+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQV 61
Query: 277 GAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHNPVA 438
G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH PV+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 439 FNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG- 585
PG + FD VD TW+ +E+ K+ GLAKSIG+SNFN Q++ IL
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
Query: 586 -QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFGPMFHDSLPSIRPD 738
+ KP QVE + + Q KL+D+CK IV++A+S G H P + P+
Sbjct: 182 LKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS--HREEPWVDPN 231
>M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 154 bits (374), Expect = 3e-37
Identities = 95/232 (40%), Positives = 136/232 (58%), Gaps = 18/232 (7%)
Frame = +1
Query: 97 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 276
+ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY NE+Q+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQV 61
Query: 277 GAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHNPVA 438
G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH PV+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 439 FNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG- 585
PG + FD VD TW+ +E+ K+ GLAKSIG+SNFN Q++ IL
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
Query: 586 -QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFGPMFHDSLPSIRPD 738
+ KP QVE + + Q KL+D+CK IV++A+S G H P + P+
Sbjct: 182 LKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS--HREEPWVDPN 231
>BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 154 bits (374), Expect = 3e-37
Identities = 95/232 (40%), Positives = 136/232 (58%), Gaps = 18/232 (7%)
Frame = +1
Query: 97 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 276
+ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY NE+Q+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQV 61
Query: 277 GAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHNPVA 438
G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH PV+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 439 FNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG- 585
PG + FD VD TW+ +E+ K+ GLAKSIG+SNFN Q++ IL
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
Query: 586 -QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFGPMFHDSLPSIRPD 738
+ KP QVE + + Q KL+D+CK IV++A+S G H P + P+
Sbjct: 182 LKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS--HREEPWVDPN 231
>BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 154 bits (374), Expect = 3e-37
Identities = 95/232 (40%), Positives = 136/232 (58%), Gaps = 18/232 (7%)
Frame = +1
Query: 97 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 276
+ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY NE+Q+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQV 61
Query: 277 GAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHNPVA 438
G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH PV+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 439 FNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG- 585
PG + FD VD TW+ +E+ K+ GLAKSIG+SNFN Q++ IL
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
Query: 586 -QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFGPMFHDSLPSIRPD 738
+ KP QVE + + Q KL+D+CK IV++A+S G H P + P+
Sbjct: 182 LKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS--HREEPWVDPN 231
>BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 154 bits (374), Expect = 3e-37
Identities = 95/232 (40%), Positives = 136/232 (58%), Gaps = 18/232 (7%)
Frame = +1
Query: 97 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 276
+ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY NE+Q+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQV 61
Query: 277 GAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHNPVA 438
G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH PV+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 439 FNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG- 585
PG + FD VD TW+ +E+ K+ GLAKSIG+SNFN Q++ IL
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
Query: 586 -QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFGPMFHDSLPSIRPD 738
+ KP QVE + + Q KL+D+CK IV++A+S G H P + P+
Sbjct: 182 LKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS--HREEPWVDPN 231
>BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 154 bits (374), Expect = 3e-37
Identities = 95/232 (40%), Positives = 136/232 (58%), Gaps = 18/232 (7%)
Frame = +1
Query: 97 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 276
+ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY NE+Q+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQV 61
Query: 277 GAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHNPVA 438
G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH PV+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 439 FNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG- 585
PG + FD VD TW+ +E+ K+ GLAKSIG+SNFN Q++ IL
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
Query: 586 -QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFGPMFHDSLPSIRPD 738
+ KP QVE + + Q KL+D+CK IV++A+S G H P + P+
Sbjct: 182 LKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS--HREEPWVDPN 231
>AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 154 bits (374), Expect = 3e-37
Identities = 95/232 (40%), Positives = 136/232 (58%), Gaps = 18/232 (7%)
Frame = +1
Query: 97 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 276
+ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY NE+Q+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQV 61
Query: 277 GAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHNPVA 438
G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH PV+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 439 FNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG- 585
PG + FD VD TW+ +E+ K+ GLAKSIG+SNFN Q++ IL
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
Query: 586 -QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFGPMFHDSLPSIRPD 738
+ KP QVE + + Q KL+D+CK IV++A+S G H P + P+
Sbjct: 182 LKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS--HREEPWVDPN 231
>AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 154 bits (374), Expect = 3e-37
Identities = 95/232 (40%), Positives = 136/232 (58%), Gaps = 18/232 (7%)
Frame = +1
Query: 97 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 276
+ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY NE+Q+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQV 61
Query: 277 GAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHNPVA 438
G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH PV+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 439 FNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG- 585
PG + FD VD TW+ +E+ K+ GLAKSIG+SNFN Q++ IL
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
Query: 586 -QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFGPMFHDSLPSIRPD 738
+ KP QVE + + Q KL+D+CK IV++A+S G H P + P+
Sbjct: 182 LKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS--HREEPWVDPN 231
>AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 154 bits (374), Expect = 3e-37
Identities = 95/232 (40%), Positives = 136/232 (58%), Gaps = 18/232 (7%)
Frame = +1
Query: 97 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 276
+ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY NE+Q+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQV 61
Query: 277 GAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHNPVA 438
G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH PV+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 439 FNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG- 585
PG + FD VD TW+ +E+ K+ GLAKSIG+SNFN Q++ IL
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
Query: 586 -QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFGPMFHDSLPSIRPD 738
+ KP QVE + + Q KL+D+CK IV++A+S G H P + P+
Sbjct: 182 LKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS--HREEPWVDPN 231
>AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid
dehydrogenase type IIb protein.
Length = 323
Score = 153 bits (372), Expect = 5e-37
Identities = 93/223 (41%), Positives = 133/223 (59%), Gaps = 18/223 (8%)
Frame = +1
Query: 85 KASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN 264
K + LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY N
Sbjct: 4 KQQCVKLNDGHFMPVLGFGTY------APPEVPRSKALEVSKLAIEAGFRHIDSAHLYNN 57
Query: 265 EDQIGAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIH 426
E+Q+G A+R+ + REDIF +KL + R ++V+ LE SL + + YVDLYLIH
Sbjct: 58 EEQVGLAIRSKIADGSVKREDIFYTSKLWSTSHRPELVRPALENSLKKAQLDYVDLYLIH 117
Query: 427 NPVAFNPGFK-------G---FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL 576
+P++ PG + G FDIVD TW+ ME+ K+ GLAKSIG+SNFN Q++ IL
Sbjct: 118 SPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMIL 177
Query: 577 ENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFG 699
+ KP QVE + + + KL+D+CK IV++A+S G
Sbjct: 178 NKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALG 220
>AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 153 bits (372), Expect = 5e-37
Identities = 94/227 (41%), Positives = 128/227 (56%), Gaps = 18/227 (7%)
Frame = +1
Query: 85 KASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN 264
K ++ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY N
Sbjct: 4 KYQRVELNDGHFMPVLGFGTY------APPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNN 57
Query: 265 EDQIGAAVRAS----GIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIH 426
E+Q+G A+R+ + REDIF +KL + V LE SL +L + YVDLYL+H
Sbjct: 58 EEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLH 117
Query: 427 NPVAFNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL 576
P+A PG FD VD TW+ ME+ K+ GLAKSIG+SNFN Q++ IL
Sbjct: 118 FPMALKPGETPLPKDENGKVIFDTVDLCATWEVMEKCKDAGLAKSIGVSNFNCRQLEMIL 177
Query: 577 ENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFGPMFH 711
+ KP QVE + +L Q KL+D+CK IV++A S G H
Sbjct: 178 NKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRH 224
>S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase
protein.
Length = 323
Score = 153 bits (371), Expect = 6e-37
Identities = 94/227 (41%), Positives = 128/227 (56%), Gaps = 18/227 (7%)
Frame = +1
Query: 85 KASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN 264
K ++ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY N
Sbjct: 4 KYQRVELNDGHFMPVLGFGTY------APPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNN 57
Query: 265 EDQIGAAVRAS----GIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIH 426
E+Q+G A+R+ + REDIF +KL + V LE SL +L + YVDLYL+H
Sbjct: 58 EEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLH 117
Query: 427 NPVAFNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL 576
P+A PG FD VD TW+ ME+ K+ GLAKSIG+SNFN Q++ IL
Sbjct: 118 FPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMIL 177
Query: 577 ENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFGPMFH 711
+ KP QVE + +L Q KL+D+CK IV++A S G H
Sbjct: 178 NKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRH 224
>D26125-1|BAA05122.1| 321|Homo sapiens 3
alpha-hydroxysteroid/dihydrodiol dehydrogenase DD4
protein.
Length = 321
Score = 153 bits (371), Expect = 6e-37
Identities = 94/227 (41%), Positives = 128/227 (56%), Gaps = 18/227 (7%)
Frame = +1
Query: 85 KASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN 264
K ++ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY N
Sbjct: 2 KYQRVELNDGHFMPVLGFGTY------APPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNN 55
Query: 265 EDQIGAAVRAS----GIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIH 426
E+Q+G A+R+ + REDIF +KL + V LE SL +L + YVDLYL+H
Sbjct: 56 EEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLH 115
Query: 427 NPVAFNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL 576
P+A PG FD VD TW+ ME+ K+ GLAKSIG+SNFN Q++ IL
Sbjct: 116 FPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMIL 175
Query: 577 ENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFGPMFH 711
+ KP QVE + +L Q KL+D+CK IV++A S G H
Sbjct: 176 NKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRH 222
>AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 153 bits (371), Expect = 6e-37
Identities = 94/227 (41%), Positives = 128/227 (56%), Gaps = 18/227 (7%)
Frame = +1
Query: 85 KASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN 264
K ++ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY N
Sbjct: 4 KYQRVELNDGHFMPVLGFGTY------APPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNN 57
Query: 265 EDQIGAAVRAS----GIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIH 426
E+Q+G A+R+ + REDIF +KL + V LE SL +L + YVDLYL+H
Sbjct: 58 EEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLH 117
Query: 427 NPVAFNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL 576
P+A PG FD VD TW+ ME+ K+ GLAKSIG+SNFN Q++ IL
Sbjct: 118 FPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMIL 177
Query: 577 ENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFGPMFH 711
+ KP QVE + +L Q KL+D+CK IV++A S G H
Sbjct: 178 NKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRH 224
>AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 153 bits (371), Expect = 6e-37
Identities = 94/227 (41%), Positives = 128/227 (56%), Gaps = 18/227 (7%)
Frame = +1
Query: 85 KASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN 264
K ++ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY N
Sbjct: 4 KYQRVELNDGHFMPVLGFGTY------APPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNN 57
Query: 265 EDQIGAAVRAS----GIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIH 426
E+Q+G A+R+ + REDIF +KL + V LE SL +L + YVDLYL+H
Sbjct: 58 EEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLH 117
Query: 427 NPVAFNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL 576
P+A PG FD VD TW+ ME+ K+ GLAKSIG+SNFN Q++ IL
Sbjct: 118 FPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMIL 177
Query: 577 ENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFGPMFH 711
+ KP QVE + +L Q KL+D+CK IV++A S G H
Sbjct: 178 NKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRH 224
>AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 153 bits (371), Expect = 6e-37
Identities = 94/227 (41%), Positives = 128/227 (56%), Gaps = 18/227 (7%)
Frame = +1
Query: 85 KASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN 264
K ++ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY N
Sbjct: 4 KYQRVELNDGHFMPVLGFGTY------APPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNN 57
Query: 265 EDQIGAAVRAS----GIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIH 426
E+Q+G A+R+ + REDIF +KL + V LE SL +L + YVDLYL+H
Sbjct: 58 EEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLH 117
Query: 427 NPVAFNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL 576
P+A PG FD VD TW+ ME+ K+ GLAKSIG+SNFN Q++ IL
Sbjct: 118 FPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMIL 177
Query: 577 ENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFGPMFH 711
+ KP QVE + +L Q KL+D+CK IV++A S G H
Sbjct: 178 NKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRH 224
>D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein.
Length = 325
Score = 153 bits (370), Expect = 8e-37
Identities = 93/223 (41%), Positives = 132/223 (59%), Gaps = 18/223 (8%)
Frame = +1
Query: 85 KASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN 264
K + LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY N
Sbjct: 6 KQQCVKLNDGHFMPVLGFGTY------APPEVPRSKALEVTKLAIEAGFRHIDSAHLYNN 59
Query: 265 EDQIGAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIH 426
E+Q+G A+R+ + REDIF +KL R ++V+ LE SL + + YVDLYLIH
Sbjct: 60 EEQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIH 119
Query: 427 NPVAFNPGFK-------G---FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL 576
+P++ PG + G FDIVD TW+ ME+ K+ GLAKSIG+SNFN Q++ IL
Sbjct: 120 SPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMIL 179
Query: 577 ENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFG 699
+ KP QVE + + + KL+D+CK IV++A+S G
Sbjct: 180 NKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALG 222
>CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 153 bits (370), Expect = 8e-37
Identities = 92/222 (41%), Positives = 135/222 (60%), Gaps = 18/222 (8%)
Frame = +1
Query: 88 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 267
AS++ LN+G +P LGLGT+ + PG + VK A++ GYR ID A +Y NE
Sbjct: 2 ASRLLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNE 52
Query: 268 DQIGAAV----RASGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHN 429
+++G A+ R + RE++FIV+KL +++ +VK +K+L+ L + Y+DLYLIH
Sbjct: 53 NEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHW 112
Query: 430 PVAFNPGFKGFDI----------VDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILE 579
P+ F PG + F + + LDTW MEE + GL K+IGISNFN Q++ IL
Sbjct: 113 PIGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILN 172
Query: 580 NG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFG 699
+ KP+V Q+E + +L Q+KLI YC+ GIVV A+SP G
Sbjct: 173 KPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 214
>BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 153 bits (370), Expect = 8e-37
Identities = 94/227 (41%), Positives = 128/227 (56%), Gaps = 18/227 (7%)
Frame = +1
Query: 85 KASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN 264
K ++ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY N
Sbjct: 4 KYQRVELNDGHFMPVLGFGTY------APPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNN 57
Query: 265 EDQIGAAVRAS----GIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIH 426
E+Q+G A+R+ + REDIF +KL + V LE SL +L + YVDLYL+H
Sbjct: 58 EEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLH 117
Query: 427 NPVAFNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL 576
P+A PG FD VD TW+ ME+ K+ GLAKSIG+SNFN Q++ IL
Sbjct: 118 FPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNYRQLEMIL 177
Query: 577 ENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFGPMFH 711
+ KP QVE + +L Q KL+D+CK IV++A S G H
Sbjct: 178 NKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRH 224
>AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthase
protein.
Length = 323
Score = 153 bits (370), Expect = 8e-37
Identities = 93/223 (41%), Positives = 132/223 (59%), Gaps = 18/223 (8%)
Frame = +1
Query: 85 KASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN 264
K + LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY N
Sbjct: 4 KQQCVKLNDGHFMPVLGFGTY------APPEVPRSKALEVTKLAIEAGFRHIDSAHLYNN 57
Query: 265 EDQIGAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIH 426
E+Q+G A+R+ + REDIF +KL R ++V+ LE SL + + YVDLYLIH
Sbjct: 58 EEQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIH 117
Query: 427 NPVAFNPGFK-------G---FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL 576
+P++ PG + G FDIVD TW+ ME+ K+ GLAKSIG+SNFN Q++ IL
Sbjct: 118 SPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMIL 177
Query: 577 ENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFG 699
+ KP QVE + + + KL+D+CK IV++A+S G
Sbjct: 178 NKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALG 220
>AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein.
Length = 323
Score = 153 bits (370), Expect = 8e-37
Identities = 93/223 (41%), Positives = 132/223 (59%), Gaps = 18/223 (8%)
Frame = +1
Query: 85 KASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN 264
K + LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY N
Sbjct: 4 KQQCVKLNDGHFMPVLGFGTY------APPEVPRSKALEVTKLAIEAGFRHIDSAHLYNN 57
Query: 265 EDQIGAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIH 426
E+Q+G A+R+ + REDIF +KL R ++V+ LE SL + + YVDLYLIH
Sbjct: 58 EEQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIH 117
Query: 427 NPVAFNPGFK-------G---FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL 576
+P++ PG + G FDIVD TW+ ME+ K+ GLAKSIG+SNFN Q++ IL
Sbjct: 118 SPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMIL 177
Query: 577 ENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFG 699
+ KP QVE + + + KL+D+CK IV++A+S G
Sbjct: 178 NKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALG 220
>J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 152 bits (369), Expect = 1e-36
Identities = 93/222 (41%), Positives = 134/222 (60%), Gaps = 18/222 (8%)
Frame = +1
Query: 88 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 267
AS+I LN+G +P LGLGT+ + PG + VK A++ GYR ID A +Y NE
Sbjct: 2 ASRILLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNE 52
Query: 268 DQIGAAV----RASGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHN 429
+++G A+ R + RE++FIV+KL +++ +VK +K+L+ L + Y+DLYLIH
Sbjct: 53 NEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHW 112
Query: 430 PVAFNPGFKGFDI----------VDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILE 579
P F PG + F + + LDTW MEE + GL K+IGISNFN Q++ IL
Sbjct: 113 PTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILN 172
Query: 580 NG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFG 699
+ KP+V Q+E + +L Q+KLI YC+ GIVV A+SP G
Sbjct: 173 KPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 214
>BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 152 bits (369), Expect = 1e-36
Identities = 92/219 (42%), Positives = 131/219 (59%), Gaps = 18/219 (8%)
Frame = +1
Query: 97 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 276
+ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY NE+Q+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQV 61
Query: 277 GAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHNPVA 438
G A+R+ + REDIF +KL R ++V+ LE SL + + YVDLYLIH+P++
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMS 121
Query: 439 FNPGFK-------G---FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG- 585
PG + G FDIVD TW+ ME+ K+ GLAKSIG+SNFN Q++ IL
Sbjct: 122 LKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
Query: 586 -QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFG 699
+ KP QVE + + + KL+D+CK IV++A+S G
Sbjct: 182 LKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALG 220
>BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 152 bits (369), Expect = 1e-36
Identities = 92/219 (42%), Positives = 131/219 (59%), Gaps = 18/219 (8%)
Frame = +1
Query: 97 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 276
+ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY NE+Q+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQV 61
Query: 277 GAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHNPVA 438
G A+R+ + REDIF +KL R ++V+ LE SL + + YVDLYLIH+P++
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMS 121
Query: 439 FNPGFK-------G---FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG- 585
PG + G FDIVD TW+ ME+ K+ GLAKSIG+SNFN Q++ IL
Sbjct: 122 LKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
Query: 586 -QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFG 699
+ KP QVE + + + KL+D+CK IV++A+S G
Sbjct: 182 LKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALG 220
>BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 152 bits (369), Expect = 1e-36
Identities = 92/219 (42%), Positives = 131/219 (59%), Gaps = 18/219 (8%)
Frame = +1
Query: 97 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 276
+ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY NE+Q+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQV 61
Query: 277 GAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHNPVA 438
G A+R+ + REDIF +KL R ++V+ LE SL + + YVDLYLIH+P++
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMS 121
Query: 439 FNPGFK-------G---FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG- 585
PG + G FDIVD TW+ ME+ K+ GLAKSIG+SNFN Q++ IL
Sbjct: 122 LKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
Query: 586 -QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFG 699
+ KP QVE + + + KL+D+CK IV++A+S G
Sbjct: 182 LKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALG 220
>AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 152 bits (369), Expect = 1e-36
Identities = 92/219 (42%), Positives = 131/219 (59%), Gaps = 18/219 (8%)
Frame = +1
Query: 97 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 276
+ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY NE+Q+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQV 61
Query: 277 GAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHNPVA 438
G A+R+ + REDIF +KL R ++V+ LE SL + + YVDLYLIH+P++
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMS 121
Query: 439 FNPGFK-------G---FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG- 585
PG + G FDIVD TW+ ME+ K+ GLAKSIG+SNFN Q++ IL
Sbjct: 122 LKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
Query: 586 -QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFG 699
+ KP QVE + + + KL+D+CK IV++A+S G
Sbjct: 182 LKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALG 220
>S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase
homolog protein.
Length = 320
Score = 152 bits (368), Expect = 1e-36
Identities = 90/221 (40%), Positives = 130/221 (58%), Gaps = 18/221 (8%)
Frame = +1
Query: 97 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 276
+ LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY NE+Q+
Sbjct: 5 VKLNDGHFMPVLGFGTY------APAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQV 58
Query: 277 GAAVRAS----GIPREDIFIVTKLPMDNQRDVVKQ--LEKSLARLNMSYVDLYLIHNPVA 438
G A+R+ + REDIF +KL ++ R + + LE+SL L + YVDLYLIH PV+
Sbjct: 59 GLAIRSKIADGSVKREDIFYTSKLWCNSHRPELDRPALERSLKNLQLDYVDLYLIHFPVS 118
Query: 439 FNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG- 585
PG + FD VD TW+ +E+ K+ LAKSIG+SNFN + ++ IL
Sbjct: 119 VKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAELAKSIGVSNFNRSTLEMILNKPG 178
Query: 586 -QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFGPM 705
Q+KP QVE + + Q KL+D+CK IV++A+S G +
Sbjct: 179 LQVKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSL 219
>S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 152 bits (368), Expect = 1e-36
Identities = 93/223 (41%), Positives = 132/223 (59%), Gaps = 18/223 (8%)
Frame = +1
Query: 85 KASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN 264
K + LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY N
Sbjct: 4 KQQCVKLNDGHFMPVLGFGTY------APPEVPRSKALEVTKLAIEAGFRHIDSAHLYNN 57
Query: 265 EDQIGAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIH 426
E+Q+G A+R+ + REDIF +KL R ++V+ LE SL + + YVDLYLIH
Sbjct: 58 EEQVGLAIRSKIADGSVEREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIH 117
Query: 427 NPVAFNPGFK-------G---FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL 576
+P++ PG + G FDIVD TW+ ME+ K+ GLAKSIG+SNFN Q++ IL
Sbjct: 118 SPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEIIL 177
Query: 577 ENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFG 699
+ KP QVE + + + KL+D+CK IV++A+S G
Sbjct: 178 NKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALG 220
>X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for
aldose reductase (EC 1.1.1.2). ).
Length = 316
Score = 151 bits (367), Expect = 2e-36
Identities = 92/222 (41%), Positives = 134/222 (60%), Gaps = 18/222 (8%)
Frame = +1
Query: 88 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 267
AS++ LN+G +P LGLGT+ + PG + VK A++ GYR ID A +Y NE
Sbjct: 2 ASRLLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNE 52
Query: 268 DQIGAAV----RASGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHN 429
+++G A+ R + RE++FIV+KL +++ +VK +K+L+ L + Y+DLYLIH
Sbjct: 53 NEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHW 112
Query: 430 PVAFNPGFKGFDI----------VDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILE 579
P F PG + F + + LDTW MEE + GL K+IGISNFN Q++ IL
Sbjct: 113 PTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILN 172
Query: 580 NG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFG 699
+ KP+V Q+E + +L Q+KLI YC+ GIVV A+SP G
Sbjct: 173 KPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 214
>M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 151 bits (367), Expect = 2e-36
Identities = 92/222 (41%), Positives = 134/222 (60%), Gaps = 18/222 (8%)
Frame = +1
Query: 88 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 267
AS++ LN+G +P LGLGT+ + PG + VK A++ GYR ID A +Y NE
Sbjct: 2 ASRLLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNE 52
Query: 268 DQIGAAV----RASGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHN 429
+++G A+ R + RE++FIV+KL +++ +VK +K+L+ L + Y+DLYLIH
Sbjct: 53 NEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHW 112
Query: 430 PVAFNPGFKGFDI----------VDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILE 579
P F PG + F + + LDTW MEE + GL K+IGISNFN Q++ IL
Sbjct: 113 PTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILN 172
Query: 580 NG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFG 699
+ KP+V Q+E + +L Q+KLI YC+ GIVV A+SP G
Sbjct: 173 KPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 214
>M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose
reductase mRNA, complete cds. ).
Length = 316
Score = 151 bits (367), Expect = 2e-36
Identities = 92/222 (41%), Positives = 134/222 (60%), Gaps = 18/222 (8%)
Frame = +1
Query: 88 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 267
AS++ LN+G +P LGLGT+ + PG + VK A++ GYR ID A +Y NE
Sbjct: 2 ASRLLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNE 52
Query: 268 DQIGAAV----RASGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHN 429
+++G A+ R + RE++FIV+KL +++ +VK +K+L+ L + Y+DLYLIH
Sbjct: 53 NEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHW 112
Query: 430 PVAFNPGFKGFDI----------VDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILE 579
P F PG + F + + LDTW MEE + GL K+IGISNFN Q++ IL
Sbjct: 113 PTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILN 172
Query: 580 NG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFG 699
+ KP+V Q+E + +L Q+KLI YC+ GIVV A+SP G
Sbjct: 173 KPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 214
>L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 151 bits (367), Expect = 2e-36
Identities = 93/223 (41%), Positives = 132/223 (59%), Gaps = 18/223 (8%)
Frame = +1
Query: 85 KASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN 264
K + LNDG+ +P LG GT+ EV + + K A+EAG+R ID+A LY N
Sbjct: 4 KQQCVKLNDGHFMPVLGFGTY------APPEVPRSKALEVTKLAIEAGFRHIDSAHLYNN 57
Query: 265 EDQIGAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIH 426
E+Q+G A+R+ + REDIF +KL R ++V+ LE SL + + YVDLYLIH
Sbjct: 58 EEQVGLAIRSKIADGSVMREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIH 117
Query: 427 NPVAFNPGFK-------G---FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL 576
+P++ PG + G FDIVD TW+ ME+ K+ GLAKSIG+SNFN Q++ IL
Sbjct: 118 SPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEIIL 177
Query: 577 ENG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFG 699
+ KP QVE + + + KL+D+CK IV++A+S G
Sbjct: 178 NKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALG 220
>J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 151 bits (367), Expect = 2e-36
Identities = 92/222 (41%), Positives = 134/222 (60%), Gaps = 18/222 (8%)
Frame = +1
Query: 88 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 267
AS++ LN+G +P LGLGT+ + PG + VK A++ GYR ID A +Y NE
Sbjct: 2 ASRLLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNE 52
Query: 268 DQIGAAV----RASGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHN 429
+++G A+ R + RE++FIV+KL +++ +VK +K+L+ L + Y+DLYLIH
Sbjct: 53 NEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHW 112
Query: 430 PVAFNPGFKGFDI----------VDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILE 579
P F PG + F + + LDTW MEE + GL K+IGISNFN Q++ IL
Sbjct: 113 PTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILN 172
Query: 580 NG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFG 699
+ KP+V Q+E + +L Q+KLI YC+ GIVV A+SP G
Sbjct: 173 KPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 214
>J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 151 bits (367), Expect = 2e-36
Identities = 92/222 (41%), Positives = 134/222 (60%), Gaps = 18/222 (8%)
Frame = +1
Query: 88 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 267
AS++ LN+G +P LGLGT+ + PG + VK A++ GYR ID A +Y NE
Sbjct: 2 ASRLLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNE 52
Query: 268 DQIGAAV----RASGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHN 429
+++G A+ R + RE++FIV+KL +++ +VK +K+L+ L + Y+DLYLIH
Sbjct: 53 NEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHW 112
Query: 430 PVAFNPGFKGFDI----------VDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILE 579
P F PG + F + + LDTW MEE + GL K+IGISNFN Q++ IL
Sbjct: 113 PTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILN 172
Query: 580 NG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFG 699
+ KP+V Q+E + +L Q+KLI YC+ GIVV A+SP G
Sbjct: 173 KPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 214
>CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 151 bits (367), Expect = 2e-36
Identities = 92/222 (41%), Positives = 134/222 (60%), Gaps = 18/222 (8%)
Frame = +1
Query: 88 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 267
AS++ LN+G +P LGLGT+ + PG + VK A++ GYR ID A +Y NE
Sbjct: 2 ASRLLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNE 52
Query: 268 DQIGAAV----RASGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHN 429
+++G A+ R + RE++FIV+KL +++ +VK +K+L+ L + Y+DLYLIH
Sbjct: 53 NEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHW 112
Query: 430 PVAFNPGFKGFDI----------VDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILE 579
P F PG + F + + LDTW MEE + GL K+IGISNFN Q++ IL
Sbjct: 113 PTGFRPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILS 172
Query: 580 NG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFG 699
+ KP+V Q+E + +L Q+KLI YC+ GIVV A+SP G
Sbjct: 173 KPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 214
>BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 151 bits (367), Expect = 2e-36
Identities = 92/222 (41%), Positives = 134/222 (60%), Gaps = 18/222 (8%)
Frame = +1
Query: 88 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 267
AS++ LN+G +P LGLGT+ + PG + VK A++ GYR ID A +Y NE
Sbjct: 2 ASRLLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNE 52
Query: 268 DQIGAAV----RASGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHN 429
+++G A+ R + RE++FIV+KL +++ +VK +K+L+ L + Y+DLYLIH
Sbjct: 53 NEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHW 112
Query: 430 PVAFNPGFKGFDI----------VDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILE 579
P F PG + F + + LDTW MEE + GL K+IGISNFN Q++ IL
Sbjct: 113 PTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILN 172
Query: 580 NG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFG 699
+ KP+V Q+E + +L Q+KLI YC+ GIVV A+SP G
Sbjct: 173 KPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 214
>BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 151 bits (367), Expect = 2e-36
Identities = 92/222 (41%), Positives = 134/222 (60%), Gaps = 18/222 (8%)
Frame = +1
Query: 88 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 267
AS++ LN+G +P LGLGT+ + PG + VK A++ GYR ID A +Y NE
Sbjct: 2 ASRLLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNE 52
Query: 268 DQIGAAV----RASGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHN 429
+++G A+ R + RE++FIV+KL +++ +VK +K+L+ L + Y+DLYLIH
Sbjct: 53 NEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHW 112
Query: 430 PVAFNPGFKGFDI----------VDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILE 579
P F PG + F + + LDTW MEE + GL K+IGISNFN Q++ IL
Sbjct: 113 PTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILN 172
Query: 580 NG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFG 699
+ KP+V Q+E + +L Q+KLI YC+ GIVV A+SP G
Sbjct: 173 KPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 214
>BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 151 bits (367), Expect = 2e-36
Identities = 92/222 (41%), Positives = 134/222 (60%), Gaps = 18/222 (8%)
Frame = +1
Query: 88 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 267
AS++ LN+G +P LGLGT+ + PG + VK A++ GYR ID A +Y NE
Sbjct: 2 ASRLLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNE 52
Query: 268 DQIGAAV----RASGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHN 429
+++G A+ R + RE++FIV+KL +++ +VK +K+L+ L + Y+DLYLIH
Sbjct: 53 NEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHW 112
Query: 430 PVAFNPGFKGFDI----------VDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILE 579
P F PG + F + + LDTW MEE + GL K+IGISNFN Q++ IL
Sbjct: 113 PTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILN 172
Query: 580 NG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFG 699
+ KP+V Q+E + +L Q+KLI YC+ GIVV A+SP G
Sbjct: 173 KPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 214
>AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen
HD-CL-07 protein.
Length = 316
Score = 151 bits (367), Expect = 2e-36
Identities = 92/222 (41%), Positives = 134/222 (60%), Gaps = 18/222 (8%)
Frame = +1
Query: 88 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 267
AS++ LN+G +P LGLGT+ + PG + VK A++ GYR ID A +Y NE
Sbjct: 2 ASRLLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNE 52
Query: 268 DQIGAAV----RASGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHN 429
+++G A+ R + RE++FIV+KL +++ +VK +K+L+ L + Y+DLYLIH
Sbjct: 53 NEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHW 112
Query: 430 PVAFNPGFKGFDI----------VDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILE 579
P F PG + F + + LDTW MEE + GL K+IGISNFN Q++ IL
Sbjct: 113 PTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILN 172
Query: 580 NG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFG 699
+ KP+V Q+E + +L Q+KLI YC+ GIVV A+SP G
Sbjct: 173 KPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 214
>AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 151 bits (367), Expect = 2e-36
Identities = 92/222 (41%), Positives = 134/222 (60%), Gaps = 18/222 (8%)
Frame = +1
Query: 88 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 267
AS++ LN+G +P LGLGT+ + PG + VK A++ GYR ID A +Y NE
Sbjct: 2 ASRLLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNE 52
Query: 268 DQIGAAV----RASGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHN 429
+++G A+ R + RE++FIV+KL +++ +VK +K+L+ L + Y+DLYLIH
Sbjct: 53 NEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHW 112
Query: 430 PVAFNPGFKGFDI----------VDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILE 579
P F PG + F + + LDTW MEE + GL K+IGISNFN Q++ IL
Sbjct: 113 PTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILN 172
Query: 580 NG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFG 699
+ KP+V Q+E + +L Q+KLI YC+ GIVV A+SP G
Sbjct: 173 KPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 214
>U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 151 bits (366), Expect = 3e-36
Identities = 94/232 (40%), Positives = 135/232 (58%), Gaps = 18/232 (7%)
Frame = +1
Query: 97 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 276
+ LNDG+ +P LG GT+ EV + + VK A+EAG+ ID+A +Y NE+Q+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQV 61
Query: 277 GAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHNPVA 438
G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH PV+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 439 FNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG- 585
PG + FD VD TW+ ME+ K+ GLAKSIG+SNFN ++ IL
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPG 181
Query: 586 -QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFGPMFHDSLPSIRPD 738
+ KP QVE + + Q KL+D+CK IV++A+S G H P + P+
Sbjct: 182 LKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS--HREEPWVDPN 231
>S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 151 bits (366), Expect = 3e-36
Identities = 94/232 (40%), Positives = 135/232 (58%), Gaps = 18/232 (7%)
Frame = +1
Query: 97 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 276
+ LNDG+ +P LG GT+ EV + + VK A+EAG+ ID+A +Y NE+Q+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQV 61
Query: 277 GAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHNPVA 438
G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH PV+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 439 FNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQ 588
PG + FD VD TW+ ME+ K+ GLAKSIG+SNFN ++ IL
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNEPG 181
Query: 589 IK--PSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFGPMFHDSLPSIRPD 738
+K P QVE + + Q KL+D+CK IV++A+S G H P + P+
Sbjct: 182 LKYEPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS--HREEPWVDPN 231
>L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol
dehydrogenase/bile acid-binding protein protein.
Length = 323
Score = 151 bits (366), Expect = 3e-36
Identities = 94/232 (40%), Positives = 134/232 (57%), Gaps = 18/232 (7%)
Frame = +1
Query: 97 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 276
+ LNDG+ +P LG GT+ EV + + VK A+EAGY ID+A +Y NE+Q+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEAVKLAIEAGYHHIDSAHVYNNEEQV 61
Query: 277 GAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHNPVA 438
G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + Y DLYLIH PV+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYADLYLIHFPVS 121
Query: 439 FNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQ 588
PG + FD VD TW+ ME+ K+ GLAKSIG+SNFN ++ IL
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNEPG 181
Query: 589 IK--PSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFGPMFHDSLPSIRPD 738
+K P QVE + + Q KL+D+CK IV++A+S G H P + P+
Sbjct: 182 LKYEPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS--HREEPWVDPN 231
>BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 151 bits (366), Expect = 3e-36
Identities = 94/232 (40%), Positives = 135/232 (58%), Gaps = 18/232 (7%)
Frame = +1
Query: 97 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 276
+ LNDG+ +P LG GT+ EV + + VK A+EAG+ ID+A +Y NE+Q+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQV 61
Query: 277 GAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHNPVA 438
G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH PV+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 439 FNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG- 585
PG + FD VD TW+ ME+ K+ GLAKSIG+SNFN ++ IL
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPG 181
Query: 586 -QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFGPMFHDSLPSIRPD 738
+ KP QVE + + Q KL+D+CK IV++A+S G H P + P+
Sbjct: 182 LKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS--HREEPWVDPN 231
>BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 151 bits (366), Expect = 3e-36
Identities = 94/232 (40%), Positives = 135/232 (58%), Gaps = 18/232 (7%)
Frame = +1
Query: 97 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 276
+ LNDG+ +P LG GT+ EV + + VK A+EAG+ ID+A +Y NE+Q+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQV 61
Query: 277 GAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHNPVA 438
G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH PV+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 439 FNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG- 585
PG + FD VD TW+ ME+ K+ GLAKSIG+SNFN ++ IL
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPG 181
Query: 586 -QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFGPMFHDSLPSIRPD 738
+ KP QVE + + Q KL+D+CK IV++A+S G H P + P+
Sbjct: 182 LKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS--HREEPWVDPN 231
>BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 151 bits (366), Expect = 3e-36
Identities = 94/232 (40%), Positives = 135/232 (58%), Gaps = 18/232 (7%)
Frame = +1
Query: 97 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 276
+ LNDG+ +P LG GT+ EV + + VK A+EAG+ ID+A +Y NE+Q+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQV 61
Query: 277 GAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHNPVA 438
G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH PV+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 439 FNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG- 585
PG + FD VD TW+ ME+ K+ GLAKSIG+SNFN ++ IL
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPG 181
Query: 586 -QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFGPMFHDSLPSIRPD 738
+ KP QVE + + Q KL+D+CK IV++A+S G H P + P+
Sbjct: 182 LKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS--HREEPWVDPN 231
>AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 151 bits (366), Expect = 3e-36
Identities = 94/232 (40%), Positives = 135/232 (58%), Gaps = 18/232 (7%)
Frame = +1
Query: 97 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 276
+ LNDG+ +P LG GT+ EV + + VK A+EAG+ ID+A +Y NE+Q+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQV 61
Query: 277 GAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHNPVA 438
G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH PV+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 439 FNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG- 585
PG + FD VD TW+ ME+ K+ GLAKSIG+SNFN ++ IL
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPG 181
Query: 586 -QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFGPMFHDSLPSIRPD 738
+ KP QVE + + Q KL+D+CK IV++A+S G H P + P+
Sbjct: 182 LKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS--HREEPWVDPN 231
>AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 151 bits (366), Expect = 3e-36
Identities = 94/232 (40%), Positives = 135/232 (58%), Gaps = 18/232 (7%)
Frame = +1
Query: 97 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 276
+ LNDG+ +P LG GT+ EV + + VK A+EAG+ ID+A +Y NE+Q+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQV 61
Query: 277 GAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHNPVA 438
G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH PV+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 439 FNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG- 585
PG + FD VD TW+ ME+ K+ GLAKSIG+SNFN ++ IL
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPG 181
Query: 586 -QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFGPMFHDSLPSIRPD 738
+ KP QVE + + Q KL+D+CK IV++A+S G H P + P+
Sbjct: 182 LKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS--HREEPWVDPN 231
>AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase family
1, member C2 variant protein.
Length = 286
Score = 151 bits (366), Expect = 3e-36
Identities = 94/232 (40%), Positives = 135/232 (58%), Gaps = 18/232 (7%)
Frame = +1
Query: 97 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 276
+ LNDG+ +P LG GT+ EV + + VK A+EAG+ ID+A +Y NE+Q+
Sbjct: 21 VKLNDGHFMPVLGFGTY------APAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQV 74
Query: 277 GAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHNPVA 438
G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH PV+
Sbjct: 75 GLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 134
Query: 439 FNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG- 585
PG + FD VD TW+ ME+ K+ GLAKSIG+SNFN ++ IL
Sbjct: 135 VKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPG 194
Query: 586 -QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFGPMFHDSLPSIRPD 738
+ KP QVE + + Q KL+D+CK IV++A+S G H P + P+
Sbjct: 195 LKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS--HREEPWVDPN 244
>AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 151 bits (366), Expect = 3e-36
Identities = 94/232 (40%), Positives = 135/232 (58%), Gaps = 18/232 (7%)
Frame = +1
Query: 97 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 276
+ LNDG+ +P LG GT+ EV + + VK A+EAG+ ID+A +Y NE+Q+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQV 61
Query: 277 GAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHNPVA 438
G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH PV+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 439 FNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG- 585
PG + FD VD TW+ ME+ K+ GLAKSIG+SNFN ++ IL
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPG 181
Query: 586 -QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFGPMFHDSLPSIRPD 738
+ KP QVE + + Q KL+D+CK IV++A+S G H P + P+
Sbjct: 182 LKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS--HREEPWVDPN 231
>AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 151 bits (366), Expect = 3e-36
Identities = 94/232 (40%), Positives = 135/232 (58%), Gaps = 18/232 (7%)
Frame = +1
Query: 97 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 276
+ LNDG+ +P LG GT+ EV + + VK A+EAG+ ID+A +Y NE+Q+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQV 61
Query: 277 GAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHNPVA 438
G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH PV+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 439 FNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG- 585
PG + FD VD TW+ ME+ K+ GLAKSIG+SNFN ++ IL
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPG 181
Query: 586 -QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFGPMFHDSLPSIRPD 738
+ KP QVE + + Q KL+D+CK IV++A+S G H P + P+
Sbjct: 182 LKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS--HREEPWVDPN 231
>AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding
protein/AKR1C2/3alpha-hydroxysteroid dehydrogenase type
3 protein.
Length = 323
Score = 151 bits (366), Expect = 3e-36
Identities = 94/232 (40%), Positives = 135/232 (58%), Gaps = 18/232 (7%)
Frame = +1
Query: 97 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 276
+ LNDG+ +P LG GT+ EV + + VK A+EAG+ ID+A +Y NE+Q+
Sbjct: 8 VKLNDGHFMPVLGFGTY------APAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQV 61
Query: 277 GAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHNPVA 438
G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH PV+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 439 FNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG- 585
PG + FD VD TW+ ME+ K+ GLAKSIG+SNFN ++ IL
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPG 181
Query: 586 -QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFGPMFHDSLPSIRPD 738
+ KP QVE + + Q KL+D+CK IV++A+S G H P + P+
Sbjct: 182 LKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS--HREEPWVDPN 231
>J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein.
Length = 325
Score = 150 bits (363), Expect = 6e-36
Identities = 87/221 (39%), Positives = 128/221 (57%), Gaps = 17/221 (7%)
Frame = +1
Query: 88 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 267
AS + L+ G +P +GLGT+ + +PG + VK+AL GYR ID AA+Y NE
Sbjct: 3 ASCVLLHTGQKMPLIGLGTW---------KSEPGQVKAAVKYALSVGYRHIDCAAIYGNE 53
Query: 268 DQIGAAVR-----ASGIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIH 426
+IG A++ +PRE++F+ +KL + DV L K+LA L + Y+DLYL+H
Sbjct: 54 PEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMH 113
Query: 427 NPVAFNPGFKGF----------DIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL 576
P AF G F D Y +TWK +E GL +++G+SNFN+ QID IL
Sbjct: 114 WPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDIL 173
Query: 577 ENGQIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFG 699
++P+VLQVE + +L Q++LI +C+ G+ V A+SP G
Sbjct: 174 SVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLG 214
>CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein.
Length = 325
Score = 150 bits (363), Expect = 6e-36
Identities = 87/221 (39%), Positives = 128/221 (57%), Gaps = 17/221 (7%)
Frame = +1
Query: 88 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 267
AS + L+ G +P +GLGT+ + +PG + VK+AL GYR ID AA+Y NE
Sbjct: 3 ASCVLLHTGQKMPLIGLGTW---------KSEPGQVKAAVKYALSVGYRHIDCAAIYGNE 53
Query: 268 DQIGAAVR-----ASGIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIH 426
+IG A++ +PRE++F+ +KL + DV L K+LA L + Y+DLYL+H
Sbjct: 54 PEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMH 113
Query: 427 NPVAFNPGFKGF----------DIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL 576
P AF G F D Y +TWK +E GL +++G+SNFN+ QID IL
Sbjct: 114 WPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDIL 173
Query: 577 ENGQIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFG 699
++P+VLQVE + +L Q++LI +C+ G+ V A+SP G
Sbjct: 174 SVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLG 214
>BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 150 bits (363), Expect = 6e-36
Identities = 87/221 (39%), Positives = 128/221 (57%), Gaps = 17/221 (7%)
Frame = +1
Query: 88 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 267
AS + L+ G +P +GLGT+ + +PG + VK+AL GYR ID AA+Y NE
Sbjct: 3 ASCVLLHTGQKMPLIGLGTW---------KSEPGQVKAAVKYALSVGYRHIDCAAIYGNE 53
Query: 268 DQIGAAVR-----ASGIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIH 426
+IG A++ +PRE++F+ +KL + DV L K+LA L + Y+DLYL+H
Sbjct: 54 PEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMH 113
Query: 427 NPVAFNPGFKGF----------DIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL 576
P AF G F D Y +TWK +E GL +++G+SNFN+ QID IL
Sbjct: 114 WPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDIL 173
Query: 577 ENGQIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFG 699
++P+VLQVE + +L Q++LI +C+ G+ V A+SP G
Sbjct: 174 SVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLG 214
>BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 150 bits (363), Expect = 6e-36
Identities = 87/221 (39%), Positives = 128/221 (57%), Gaps = 17/221 (7%)
Frame = +1
Query: 88 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 267
AS + L+ G +P +GLGT+ + +PG + VK+AL GYR ID AA+Y NE
Sbjct: 3 ASCVLLHTGQKMPLIGLGTW---------KSEPGQVKAAVKYALSVGYRHIDCAAIYGNE 53
Query: 268 DQIGAAVR-----ASGIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIH 426
+IG A++ +PRE++F+ +KL + DV L K+LA L + Y+DLYL+H
Sbjct: 54 PEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMH 113
Query: 427 NPVAFNPGFKGF----------DIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL 576
P AF G F D Y +TWK +E GL +++G+SNFN+ QID IL
Sbjct: 114 WPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDIL 173
Query: 577 ENGQIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFG 699
++P+VLQVE + +L Q++LI +C+ G+ V A+SP G
Sbjct: 174 SVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLG 214
>BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 150 bits (363), Expect = 6e-36
Identities = 87/221 (39%), Positives = 128/221 (57%), Gaps = 17/221 (7%)
Frame = +1
Query: 88 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 267
AS + L+ G +P +GLGT+ + +PG + VK+AL GYR ID AA+Y NE
Sbjct: 3 ASCVLLHTGQKMPLIGLGTW---------KSEPGQVKAAVKYALSVGYRHIDCAAIYGNE 53
Query: 268 DQIGAAVR-----ASGIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIH 426
+IG A++ +PRE++F+ +KL + DV L K+LA L + Y+DLYL+H
Sbjct: 54 PEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMH 113
Query: 427 NPVAFNPGFKGF----------DIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL 576
P AF G F D Y +TWK +E GL +++G+SNFN+ QID IL
Sbjct: 114 WPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDIL 173
Query: 577 ENGQIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFG 699
++P+VLQVE + +L Q++LI +C+ G+ V A+SP G
Sbjct: 174 SVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLG 214
>AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydetase, 1 protein.
Length = 325
Score = 150 bits (363), Expect = 6e-36
Identities = 87/221 (39%), Positives = 128/221 (57%), Gaps = 17/221 (7%)
Frame = +1
Query: 88 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 267
AS + L+ G +P +GLGT+ + +PG + VK+AL GYR ID AA+Y NE
Sbjct: 3 ASCVLLHTGQKMPLIGLGTW---------KSEPGQVKAAVKYALSVGYRHIDCAAIYGNE 53
Query: 268 DQIGAAVR-----ASGIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIH 426
+IG A++ +PRE++F+ +KL + DV L K+LA L + Y+DLYL+H
Sbjct: 54 PEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMH 113
Query: 427 NPVAFNPGFKGF----------DIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL 576
P AF G F D Y +TWK +E GL +++G+SNFN+ QID IL
Sbjct: 114 WPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDIL 173
Query: 577 ENGQIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFG 699
++P+VLQVE + +L Q++LI +C+ G+ V A+SP G
Sbjct: 174 SVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLG 214
>AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 150 bits (363), Expect = 6e-36
Identities = 87/221 (39%), Positives = 128/221 (57%), Gaps = 17/221 (7%)
Frame = +1
Query: 88 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 267
AS + L+ G +P +GLGT+ + +PG + VK+AL GYR ID AA+Y NE
Sbjct: 3 ASCVLLHTGQKMPLIGLGTW---------KSEPGQVKAAVKYALSVGYRHIDCAAIYGNE 53
Query: 268 DQIGAAVR-----ASGIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIH 426
+IG A++ +PRE++F+ +KL + DV L K+LA L + Y+DLYL+H
Sbjct: 54 PEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMH 113
Query: 427 NPVAFNPGFKGF----------DIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL 576
P AF G F D Y +TWK +E GL +++G+SNFN+ QID IL
Sbjct: 114 WPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDIL 173
Query: 577 ENGQIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFG 699
++P+VLQVE + +L Q++LI +C+ G+ V A+SP G
Sbjct: 174 SVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLG 214
>AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 150 bits (363), Expect = 6e-36
Identities = 87/221 (39%), Positives = 128/221 (57%), Gaps = 17/221 (7%)
Frame = +1
Query: 88 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 267
AS + L+ G +P +GLGT+ + +PG + VK+AL GYR ID AA+Y NE
Sbjct: 3 ASCVLLHTGQKMPLIGLGTW---------KSEPGQVKAAVKYALSVGYRHIDCAAIYGNE 53
Query: 268 DQIGAAVR-----ASGIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIH 426
+IG A++ +PRE++F+ +KL + DV L K+LA L + Y+DLYL+H
Sbjct: 54 PEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMH 113
Query: 427 NPVAFNPGFKGF----------DIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL 576
P AF G F D Y +TWK +E GL +++G+SNFN+ QID IL
Sbjct: 114 WPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDIL 173
Query: 577 ENGQIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFG 699
++P+VLQVE + +L Q++LI +C+ G+ V A+SP G
Sbjct: 174 SVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLG 214
>AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase family
1, member B1 variant protein.
Length = 260
Score = 148 bits (359), Expect = 2e-35
Identities = 90/220 (40%), Positives = 132/220 (60%), Gaps = 18/220 (8%)
Frame = +1
Query: 94 KISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQ 273
++ LN+G +P LGLGT+ + PG + VK A++ GYR ID A +Y NE++
Sbjct: 1 RLLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENE 51
Query: 274 IGAAV----RASGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHNPV 435
+G A+ R + RE++FIV+KL +++ +VK +K+L+ L + Y+DLYLIH P
Sbjct: 52 VGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPT 111
Query: 436 AFNPGFKGFDI----------VDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG 585
F PG + F + + LDTW MEE + GL K+IGISNFN Q++ IL
Sbjct: 112 GFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKP 171
Query: 586 --QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFG 699
+ KP+V Q+E + +L Q+KLI YC+ GIVV A+SP G
Sbjct: 172 GLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 211
>BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 146 bits (353), Expect = 1e-34
Identities = 91/222 (40%), Positives = 133/222 (59%), Gaps = 18/222 (8%)
Frame = +1
Query: 88 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 267
AS++ LN+G +P LGLGT+ + PG + VK A++ GYR ID A +Y NE
Sbjct: 2 ASRLLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNE 52
Query: 268 DQIGAAV----RASGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHN 429
+++G A+ R + RE++FIV+KL +++ +VK +K+L+ L + Y+DLYLIH
Sbjct: 53 NEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHW 112
Query: 430 PVAFNPGFKGFDI----------VDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILE 579
P F PG + F + + LDT MEE + GL K+IGISNFN Q++ IL
Sbjct: 113 PTGFKPGKEFFPLDESGNVVPSDTNILDTRAAMEELVDEGLVKAIGISNFNHLQVEMILN 172
Query: 580 NGQIK--PSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFG 699
+K P+V Q+E + +L Q+KLI YC+ GIVV A+SP G
Sbjct: 173 KPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 214
>D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase
isoform DD1 protein.
Length = 306
Score = 145 bits (351), Expect = 2e-34
Identities = 89/215 (41%), Positives = 126/215 (58%), Gaps = 18/215 (8%)
Frame = +1
Query: 148 LGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGAAVRAS----GIPRED 315
LGF EV + + K A+EAG+R ID+A LY NE+Q+G A+R+ + RED
Sbjct: 2 LGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKRED 61
Query: 316 IFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHNPVAFNPGFKG---------- 459
IF +KL ++ R ++V+ LE+SL L + YVDLYLIH PV+ PG +
Sbjct: 62 IFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKIL 121
Query: 460 FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLG 633
FD VD TW+ +E+ K+ GLAKSIG+SNFN Q++ IL + KP QVE + +
Sbjct: 122 FDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFN 181
Query: 634 QDKLIDYCKRNGIVVMAFSPFGPMFHDSLPSIRPD 738
Q KL+D+CK IV++A+S G H P + P+
Sbjct: 182 QRKLLDFCKSKDIVLVAYSALGS--HREEPWVDPN 214
>M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordecone
reductase mRNA, complete cds. ).
Length = 308
Score = 142 bits (343), Expect = 2e-33
Identities = 87/206 (42%), Positives = 116/206 (56%), Gaps = 18/206 (8%)
Frame = +1
Query: 148 LGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGAAVRAS----GIPRED 315
LGF EV + + K A+EAG+R ID+A LY NE+Q+G A+R+ + RED
Sbjct: 4 LGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGSVKRED 63
Query: 316 IFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVAFNPGFKG---------- 459
IF +KL + V LE SL +L + YVDLYL+H P+A PG
Sbjct: 64 IFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETPLPKDENGKVI 123
Query: 460 FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLG 633
FD VD TW+ ME+ K+ GLAKSIG+SNFN Q++ IL + KP QVE + +L
Sbjct: 124 FDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLN 183
Query: 634 QDKLIDYCKRNGIVVMAFSPFGPMFH 711
Q KL+D+CK IV++A S G H
Sbjct: 184 QSKLLDFCKSKDIVLVAHSALGTQRH 209
>Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5
beta-reductase protein.
Length = 326
Score = 135 bits (326), Expect = 2e-31
Identities = 88/220 (40%), Positives = 126/220 (57%), Gaps = 18/220 (8%)
Frame = +1
Query: 94 KISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQ 273
+I L+DGNSIP +GLGT+ K G VK A++ GYR ID A +Y NE +
Sbjct: 9 RIPLSDGNSIPIIGLGTY-----SEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHE 63
Query: 274 IGAAVR---ASG-IPREDIFIVTKLPMDNQ-RDVVK-QLEKSLARLNMSYVDLYLIHNPV 435
+G A+R A G + REDIF KL N ++V+ LE++L L + YVDLY+I P+
Sbjct: 64 VGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPM 123
Query: 436 AFNPGFK-------G---FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG 585
AF PG + G + + TW+ ME K+ GL KS+G+SNFN Q++ IL
Sbjct: 124 AFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKP 183
Query: 586 QI--KPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFG 699
+ KP QVE + + Q KL+ +C+++ IV+ A+SP G
Sbjct: 184 GLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLG 223
>BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 135 bits (326), Expect = 2e-31
Identities = 88/220 (40%), Positives = 126/220 (57%), Gaps = 18/220 (8%)
Frame = +1
Query: 94 KISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQ 273
+I L+DGNSIP +GLGT+ K G VK A++ GYR ID A +Y NE +
Sbjct: 9 RIPLSDGNSIPIIGLGTY-----SEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHE 63
Query: 274 IGAAVR---ASG-IPREDIFIVTKLPMDNQ-RDVVK-QLEKSLARLNMSYVDLYLIHNPV 435
+G A+R A G + REDIF KL N ++V+ LE++L L + YVDLY+I P+
Sbjct: 64 VGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPM 123
Query: 436 AFNPGFK-------G---FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG 585
AF PG + G + + TW+ ME K+ GL KS+G+SNFN Q++ IL
Sbjct: 124 AFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKP 183
Query: 586 QI--KPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFG 699
+ KP QVE + + Q KL+ +C+++ IV+ A+SP G
Sbjct: 184 GLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLG 223
>BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 135 bits (326), Expect = 2e-31
Identities = 88/220 (40%), Positives = 126/220 (57%), Gaps = 18/220 (8%)
Frame = +1
Query: 94 KISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQ 273
+I L+DGNSIP +GLGT+ K G VK A++ GYR ID A +Y NE +
Sbjct: 9 RIPLSDGNSIPIIGLGTY-----SEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHE 63
Query: 274 IGAAVR---ASG-IPREDIFIVTKLPMDNQ-RDVVK-QLEKSLARLNMSYVDLYLIHNPV 435
+G A+R A G + REDIF KL N ++V+ LE++L L + YVDLY+I P+
Sbjct: 64 VGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPM 123
Query: 436 AFNPGFK-------G---FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG 585
AF PG + G + + TW+ ME K+ GL KS+G+SNFN Q++ IL
Sbjct: 124 AFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKP 183
Query: 586 QI--KPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFG 699
+ KP QVE + + Q KL+ +C+++ IV+ A+SP G
Sbjct: 184 GLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLG 223
>AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductase
protein.
Length = 326
Score = 135 bits (326), Expect = 2e-31
Identities = 88/220 (40%), Positives = 126/220 (57%), Gaps = 18/220 (8%)
Frame = +1
Query: 94 KISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQ 273
+I L+DGNSIP +GLGT+ K G VK A++ GYR ID A +Y NE +
Sbjct: 9 RIPLSDGNSIPIIGLGTY-----SEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHE 63
Query: 274 IGAAVR---ASG-IPREDIFIVTKLPMDNQ-RDVVK-QLEKSLARLNMSYVDLYLIHNPV 435
+G A+R A G + REDIF KL N ++V+ LE++L L + YVDLY+I P+
Sbjct: 64 VGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPM 123
Query: 436 AFNPGFK-------G---FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG 585
AF PG + G + + TW+ ME K+ GL KS+G+SNFN Q++ IL
Sbjct: 124 AFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKP 183
Query: 586 QI--KPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFG 699
+ KP QVE + + Q KL+ +C+++ IV+ A+SP G
Sbjct: 184 GLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLG 223
>U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like
peptide protein.
Length = 316
Score = 131 bits (316), Expect = 3e-30
Identities = 86/222 (38%), Positives = 126/222 (56%), Gaps = 18/222 (8%)
Frame = +1
Query: 88 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 267
A+ + L+ +P +GLGT+ + G ++ VK A++AGYR ID A +Y NE
Sbjct: 2 ATFVELSTKAKMPIVGLGTW---------KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNE 52
Query: 268 DQIGAAVRAS----GIPREDIFIVTKL-PMDNQRDVV-KQLEKSLARLNMSYVDLYLIHN 429
++G A++ + RED+FIV+KL P +R +V K EK+L L +SY+D+YLIH
Sbjct: 53 HEVGEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHW 112
Query: 430 PVAFNPGFKGFDIVD----------YLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILE 579
P F G F D +LD W+ MEE + GL K++G+SNF+ QI+++L
Sbjct: 113 PQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLN 172
Query: 580 NG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFG 699
+ KP QVE + +L Q+KLI YC GI V A+SP G
Sbjct: 173 KPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLG 214
>CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein.
Length = 316
Score = 131 bits (316), Expect = 3e-30
Identities = 86/222 (38%), Positives = 126/222 (56%), Gaps = 18/222 (8%)
Frame = +1
Query: 88 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 267
A+ + L+ +P +GLGT+ + G ++ VK A++AGYR ID A +Y NE
Sbjct: 2 ATFVELSTKAKMPIVGLGTW---------KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNE 52
Query: 268 DQIGAAVRAS----GIPREDIFIVTKL-PMDNQRDVV-KQLEKSLARLNMSYVDLYLIHN 429
++G A++ + RED+FIV+KL P +R +V K EK+L L +SY+D+YLIH
Sbjct: 53 HEVGEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHW 112
Query: 430 PVAFNPGFKGFDIVD----------YLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILE 579
P F G F D +LD W+ MEE + GL K++G+SNF+ QI+++L
Sbjct: 113 PQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLN 172
Query: 580 NG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFG 699
+ KP QVE + +L Q+KLI YC GI V A+SP G
Sbjct: 173 KPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLG 214
>BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 131 bits (316), Expect = 3e-30
Identities = 86/222 (38%), Positives = 126/222 (56%), Gaps = 18/222 (8%)
Frame = +1
Query: 88 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 267
A+ + L+ +P +GLGT+ + G ++ VK A++AGYR ID A +Y NE
Sbjct: 2 ATFVELSTKAKMPIVGLGTW---------KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNE 52
Query: 268 DQIGAAVRAS----GIPREDIFIVTKL-PMDNQRDVV-KQLEKSLARLNMSYVDLYLIHN 429
++G A++ + RED+FIV+KL P +R +V K EK+L L +SY+D+YLIH
Sbjct: 53 HEVGEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHW 112
Query: 430 PVAFNPGFKGFDIVD----------YLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILE 579
P F G F D +LD W+ MEE + GL K++G+SNF+ QI+++L
Sbjct: 113 PQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLN 172
Query: 580 NG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFG 699
+ KP QVE + +L Q+KLI YC GI V A+SP G
Sbjct: 173 KPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLG 214
>BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 131 bits (316), Expect = 3e-30
Identities = 86/222 (38%), Positives = 126/222 (56%), Gaps = 18/222 (8%)
Frame = +1
Query: 88 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 267
A+ + L+ +P +GLGT+ + G ++ VK A++AGYR ID A +Y NE
Sbjct: 2 ATFVELSTKAKMPIVGLGTW---------KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNE 52
Query: 268 DQIGAAVRAS----GIPREDIFIVTKL-PMDNQRDVV-KQLEKSLARLNMSYVDLYLIHN 429
++G A++ + RED+FIV+KL P +R +V K EK+L L +SY+D+YLIH
Sbjct: 53 HEVGEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHW 112
Query: 430 PVAFNPGFKGFDIVD----------YLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILE 579
P F G F D +LD W+ MEE + GL K++G+SNF+ QI+++L
Sbjct: 113 PQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLN 172
Query: 580 NG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFG 699
+ KP QVE + +L Q+KLI YC GI V A+SP G
Sbjct: 173 KPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLG 214
>AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase
protein.
Length = 316
Score = 131 bits (316), Expect = 3e-30
Identities = 86/222 (38%), Positives = 126/222 (56%), Gaps = 18/222 (8%)
Frame = +1
Query: 88 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 267
A+ + L+ +P +GLGT+ + G ++ VK A++AGYR ID A +Y NE
Sbjct: 2 ATFVELSTKAKMPIVGLGTW---------KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNE 52
Query: 268 DQIGAAVRAS----GIPREDIFIVTKL-PMDNQRDVV-KQLEKSLARLNMSYVDLYLIHN 429
++G A++ + RED+FIV+KL P +R +V K EK+L L +SY+D+YLIH
Sbjct: 53 HEVGEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHW 112
Query: 430 PVAFNPGFKGFDIVD----------YLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILE 579
P F G F D +LD W+ MEE + GL K++G+SNF+ QI+++L
Sbjct: 113 PQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLN 172
Query: 580 NG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFG 699
+ KP QVE + +L Q+KLI YC GI V A+SP G
Sbjct: 173 KPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLG 214
>AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase
protein.
Length = 316
Score = 126 bits (305), Expect = 6e-29
Identities = 84/222 (37%), Positives = 124/222 (55%), Gaps = 18/222 (8%)
Frame = +1
Query: 88 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 267
A+ + L+ +P +GLGT+ + G ++ VK A++AGYR ID A +Y NE
Sbjct: 2 ATFVELSTKAKMPIVGLGTW---------KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNE 52
Query: 268 DQIGAAVRAS----GIPREDIFIVTKL-PMDNQRDVV-KQLEKSLARLNMSYVDLYLIHN 429
++G A++ + RED+FI +KL P +R +V K EK+L +SY+D+YLIH
Sbjct: 53 HEVGEAIQEKIQEKAVKREDLFIASKLWPTFFERPLVRKAFEKTLKDPKLSYLDVYLIHW 112
Query: 430 PVAFNPGFKGFDIVD----------YLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILE 579
P F G F D +LD W+ MEE + GL K++G+SNF+ QI+++L
Sbjct: 113 PQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLN 172
Query: 580 NG--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFG 699
+ KP QVE + +L Q+KLI YC GI V A+SP G
Sbjct: 173 KPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLG 214
>AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase
loopADR protein.
Length = 320
Score = 72.1 bits (169), Expect(2) = 5e-27
Identities = 45/115 (39%), Positives = 66/115 (57%), Gaps = 6/115 (5%)
Frame = +1
Query: 121 IPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGAAVRA-- 294
IPA+GL ++ + PG + VK A++AGYR D A Y NE ++GA +R
Sbjct: 4 IPAVGLSSW---------KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKI 54
Query: 295 --SGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHNPVAFNP 447
+ RED+FI TKL +++ +V+ KSL L ++Y+DLYLIH P+ F P
Sbjct: 55 KEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKP 109
Score = 69.3 bits (162), Expect(2) = 5e-27
Identities = 32/78 (41%), Positives = 48/78 (61%), Gaps = 2/78 (2%)
Frame = +1
Query: 472 DYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLGQDKL 645
D+LDTW+ ME+ GL K+IG+SNFN Q++R+L + KP Q+E + +L Q L
Sbjct: 147 DFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYLTQKNL 206
Query: 646 IDYCKRNGIVVMAFSPFG 699
I +C+ + V A+ P G
Sbjct: 207 ISFCQSRDVSVTAYRPLG 224
>BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein.
Length = 307
Score = 72.1 bits (169), Expect(2) = 5e-27
Identities = 45/115 (39%), Positives = 66/115 (57%), Gaps = 6/115 (5%)
Frame = +1
Query: 121 IPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGAAVRA-- 294
IPA+GL ++ + PG + VK A++AGYR D A Y NE ++GA +R
Sbjct: 4 IPAVGLSSW---------KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKI 54
Query: 295 --SGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHNPVAFNP 447
+ RED+FI TKL +++ +V+ KSL L ++Y+DLYLIH P+ F P
Sbjct: 55 KEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKP 109
Score = 69.3 bits (162), Expect(2) = 5e-27
Identities = 32/78 (41%), Positives = 48/78 (61%), Gaps = 2/78 (2%)
Frame = +1
Query: 472 DYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLGQDKL 645
D+LDTW+ ME+ GL K+IG+SNFN Q++R+L + KP Q+E + +L Q L
Sbjct: 147 DFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYLTQKNL 206
Query: 646 IDYCKRNGIVVMAFSPFG 699
I +C+ + V A+ P G
Sbjct: 207 ISFCQSRDVSVTAYRPLG 224
>AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase
related protein 4 protein.
Length = 307
Score = 72.1 bits (169), Expect(2) = 5e-27
Identities = 45/115 (39%), Positives = 66/115 (57%), Gaps = 6/115 (5%)
Frame = +1
Query: 121 IPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGAAVRA-- 294
IPA+GL ++ + PG + VK A++AGYR D A Y NE ++GA +R
Sbjct: 4 IPAVGLSSW---------KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKI 54
Query: 295 --SGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHNPVAFNP 447
+ RED+FI TKL +++ +V+ KSL L ++Y+DLYLIH P+ F P
Sbjct: 55 KEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKP 109
Score = 69.3 bits (162), Expect(2) = 5e-27
Identities = 32/78 (41%), Positives = 48/78 (61%), Gaps = 2/78 (2%)
Frame = +1
Query: 472 DYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLGQDKL 645
D+LDTW+ ME+ GL K+IG+SNFN Q++R+L + KP Q+E + +L Q L
Sbjct: 147 DFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYLTQKNL 206
Query: 646 IDYCKRNGIVVMAFSPFG 699
I +C+ + V A+ P G
Sbjct: 207 ISFCQSRDVSVTAYRPLG 224
>AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 247
Score = 113 bits (271), Expect = 8e-25
Identities = 70/174 (40%), Positives = 102/174 (58%), Gaps = 18/174 (10%)
Frame = +1
Query: 271 QIGAAVRAS----GIPREDIFIVTKLPMDNQR-DVVKQ-LEKSLARLNMSYVDLYLIHNP 432
++G A+R+ + REDIF +KL ++ R ++V+ LE+SL L + YVDLYLIH P
Sbjct: 26 EVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFP 85
Query: 433 VAFNPGFKG----------FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILEN 582
V+ PG + FD VD TW+ +E+ K+ GLAKSIG+SNFN Q++ IL
Sbjct: 86 VSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNK 145
Query: 583 G--QIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSPFGPMFHDSLPSIRPD 738
+ KP QVE + + Q KL+D+CK IV++A+S G H P + P+
Sbjct: 146 PGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS--HREEPWVDPN 197
>AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase
related protein 2 protein.
Length = 263
Score = 72.1 bits (169), Expect(2) = 2e-21
Identities = 45/115 (39%), Positives = 66/115 (57%), Gaps = 6/115 (5%)
Frame = +1
Query: 121 IPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGAAVRA-- 294
IPA+GL ++ + PG + VK A++AGYR D A Y NE ++GA +R
Sbjct: 4 IPAVGLSSW---------KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKI 54
Query: 295 --SGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHNPVAFNP 447
+ RED+FI TKL +++ +V+ KSL L ++Y+DLYLIH P+ F P
Sbjct: 55 KEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKP 109
Score = 50.4 bits (115), Expect(2) = 2e-21
Identities = 22/61 (36%), Positives = 38/61 (62%), Gaps = 2/61 (3%)
Frame = +1
Query: 472 DYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLGQDKL 645
D+LDTW+ ME+ GL K+IG+SNFN Q++R+L + KP Q+ + + ++ +
Sbjct: 147 DFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQILIRFQIQRNVI 206
Query: 646 I 648
+
Sbjct: 207 V 207
>AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase
related protein 1 protein.
Length = 250
Score = 72.1 bits (169), Expect(2) = 2e-21
Identities = 45/115 (39%), Positives = 66/115 (57%), Gaps = 6/115 (5%)
Frame = +1
Query: 121 IPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGAAVRA-- 294
IPA+GL ++ + PG + VK A++AGYR D A Y NE ++GA +R
Sbjct: 4 IPAVGLSSW---------KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKI 54
Query: 295 --SGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHNPVAFNP 447
+ RED+FI TKL +++ +V+ KSL L ++Y+DLYLIH P+ F P
Sbjct: 55 KEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKP 109
Score = 50.4 bits (115), Expect(2) = 2e-21
Identities = 22/61 (36%), Positives = 38/61 (62%), Gaps = 2/61 (3%)
Frame = +1
Query: 472 DYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLGQDKL 645
D+LDTW+ ME+ GL K+IG+SNFN Q++R+L + KP Q+ + + ++ +
Sbjct: 147 DFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQILIRFQIQRNVI 206
Query: 646 I 648
+
Sbjct: 207 V 207
>AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydela) protein.
Length = 147
Score = 88.2 bits (209), Expect = 3e-17
Identities = 58/154 (37%), Positives = 84/154 (54%), Gaps = 17/154 (11%)
Frame = +1
Query: 88 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 267
AS + L+ G +P +GLGT+ + +PG + VK+AL GYR ID AA+Y NE
Sbjct: 3 ASCVLLHTGQKMPLIGLGTW---------KSEPGQVKAAVKYALSVGYRHIDCAAIYGNE 53
Query: 268 DQIGAAVR-----ASGIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIH 426
+IG A++ +PRE++F+ +KL + DV L K+LA L + Y+DLYL+H
Sbjct: 54 PEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMH 113
Query: 427 NPVAF----NP------GFKGFDIVDYLDTWKGM 498
P AF NP G +D Y +TWK +
Sbjct: 114 WPYAFERGDNPFPKNADGTICYDSTHYKETWKAL 147
>AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto
reductase protein.
Length = 130
Score = 83.8 bits (198), Expect = 6e-16
Identities = 51/124 (41%), Positives = 73/124 (58%), Gaps = 6/124 (4%)
Frame = +1
Query: 97 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 276
+ LNDG +P LG GT + ++V + E+ V+ A++ GYR ID+A +LNE+ I
Sbjct: 9 VKLNDGKFMPILGFGTSVA------RKVAMSNVEEAVQVAIDVGYRHIDSAYTHLNEEGI 62
Query: 277 GAAVR---ASG-IPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVA 438
G A+R A+G + R+DIF TK+ V + LE SL +L +SY+DLYL H PV
Sbjct: 63 GQAIRKKIANGTVKRKDIFYTTKVWGTFSRPELVQRGLEMSLKKLQLSYMDLYLFHFPVP 122
Query: 439 FNPG 450
PG
Sbjct: 123 LQPG 126
>AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 81.0 bits (191), Expect = 4e-15
Identities = 65/214 (30%), Positives = 110/214 (51%), Gaps = 9/214 (4%)
Frame = +1
Query: 85 KASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN 264
++ + LNDG +P LG GT+ + + K A++ G+R ID+A LY N
Sbjct: 7 QSHSVRLNDGPFMPVLGFGTY------APDHTPKSQAAEATKVAIDVGFRHIDSAYLYQN 60
Query: 265 EDQIGAAV---RASG-IPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIH 426
E+++G A+ A G + RE+IF KL V LE+SL +L YVDL++IH
Sbjct: 61 EEEVGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIH 120
Query: 427 NPVAFNPGFKGFDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG--QIKPS 600
P A G +++ ++A + +++ + +T +++ IL + KP+
Sbjct: 121 VPFAMKQ--PGKELLP--------KDASGEIILETVELC--DTWELELILNKPGLRYKPT 168
Query: 601 VLQ-VEVNLHLGQDKLIDYCKRNGIVVMAFSPFG 699
Q VE + +L Q KL+++CK IV++A+S G
Sbjct: 169 CNQVVECHPYLNQSKLLEFCKSKDIVLVAYSALG 202
>AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 81.0 bits (191), Expect = 4e-15
Identities = 65/214 (30%), Positives = 110/214 (51%), Gaps = 9/214 (4%)
Frame = +1
Query: 85 KASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN 264
++ + LNDG +P LG GT+ + + K A++ G+R ID+A LY N
Sbjct: 7 QSHSVRLNDGPFMPVLGFGTY------APDHTPKSQAAEATKVAIDVGFRHIDSAYLYQN 60
Query: 265 EDQIGAAV---RASG-IPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIH 426
E+++G A+ A G + RE+IF KL V LE+SL +L YVDL++IH
Sbjct: 61 EEEVGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIH 120
Query: 427 NPVAFNPGFKGFDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG--QIKPS 600
P A G +++ ++A + +++ + +T +++ IL + KP+
Sbjct: 121 VPFAMKQ--PGKELLP--------KDASGEIILETVELC--DTWELELILNKPGLRYKPT 168
Query: 601 VLQ-VEVNLHLGQDKLIDYCKRNGIVVMAFSPFG 699
Q VE + +L Q KL+++CK IV++A+S G
Sbjct: 169 CNQVVECHPYLNQSKLLEFCKSKDIVLVAYSALG 202
>AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase
related protein 3 protein.
Length = 222
Score = 72.1 bits (169), Expect = 2e-12
Identities = 45/115 (39%), Positives = 66/115 (57%), Gaps = 6/115 (5%)
Frame = +1
Query: 121 IPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGAAVRA-- 294
IPA+GL ++ + PG + VK A++AGYR D A Y NE ++GA +R
Sbjct: 4 IPAVGLSSW---------KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKI 54
Query: 295 --SGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHNPVAFNP 447
+ RED+FI TKL +++ +V+ KSL L ++Y+DLYLIH P+ F P
Sbjct: 55 KEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKP 109
>AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens
cDNA FLJ25413 fis, clone TST03402, highly similar to
3-OXO-5-BETA-STEROID 4-DEHYDROGENASE (EC 1.3.99.6). ).
Length = 146
Score = 68.1 bits (159), Expect = 3e-11
Identities = 32/74 (43%), Positives = 48/74 (64%), Gaps = 2/74 (2%)
Frame = +1
Query: 484 TWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQI--KPSVLQVEVNLHLGQDKLIDYC 657
TW+ ME K+ GL KS+G+SNFN Q++ IL + KP QVE + + Q KL+ +C
Sbjct: 28 TWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFC 87
Query: 658 KRNGIVVMAFSPFG 699
+++ IV+ A+SP G
Sbjct: 88 QQHDIVITAYSPLG 101
>BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 67.3 bits (157), Expect = 5e-11
Identities = 44/124 (35%), Positives = 65/124 (52%), Gaps = 6/124 (4%)
Frame = +1
Query: 85 KASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN 264
++ + LNDG +P LG GT+ + + K A++ G+R ID+A LY N
Sbjct: 7 QSHSVRLNDGPFMPVLGFGTY------APDHTPKSQAAEATKVAIDVGFRHIDSAYLYQN 60
Query: 265 EDQIGAAV---RASG-IPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIH 426
E+++G A+ A G + RE+IF KL V LE+SL +L YVDL++IH
Sbjct: 61 EEEVGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIH 120
Query: 427 NPVA 438
P A
Sbjct: 121 VPFA 124
>BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 67.3 bits (157), Expect = 5e-11
Identities = 44/124 (35%), Positives = 65/124 (52%), Gaps = 6/124 (4%)
Frame = +1
Query: 85 KASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN 264
++ + LNDG +P LG GT+ + + K A++ G+R ID+A LY N
Sbjct: 7 QSHSVRLNDGPFMPVLGFGTY------APDHTPKSQAAEATKVAIDVGFRHIDSAYLYQN 60
Query: 265 EDQIGAAV---RASG-IPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIH 426
E+++G A+ A G + RE+IF KL V LE+SL +L YVDL++IH
Sbjct: 61 EEEVGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIH 120
Query: 427 NPVA 438
P A
Sbjct: 121 VPFA 124
>AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens
cDNA FLJ16347 fis, clone TESTI2036288, moderately
similar to PROSTAGLANDIN-F SYNTHASE 1 (EC 1.1.1.188). ).
Length = 129
Score = 67.3 bits (157), Expect = 5e-11
Identities = 44/124 (35%), Positives = 65/124 (52%), Gaps = 6/124 (4%)
Frame = +1
Query: 85 KASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN 264
++ + LNDG +P LG GT+ + + K A++ G+R ID+A LY N
Sbjct: 7 QSHSVRLNDGPFMPVLGFGTY------APDHTPKSQAAEATKVAIDVGFRHIDSAYLYQN 60
Query: 265 EDQIGAAV---RASG-IPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIH 426
E+++G A+ A G + RE+IF KL V LE+SL +L YVDL++IH
Sbjct: 61 EEEVGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIH 120
Query: 427 NPVA 438
P A
Sbjct: 121 VPFA 124
>AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthase
protein.
Length = 67
Score = 56.8 bits (131), Expect = 8e-08
Identities = 25/45 (55%), Positives = 32/45 (71%)
Frame = +1
Query: 460 FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIK 594
FDIVD TW+ ME+ K+ GLAKSIG+SNFN Q++ IL +K
Sbjct: 16 FDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLK 60
>U16953-1|AAC50122.1| 408|Homo sapiens potassium channel beta3
subunit protein.
Length = 408
Score = 46.4 bits (105), Expect = 1e-04
Identities = 41/145 (28%), Positives = 68/145 (46%), Gaps = 13/145 (8%)
Frame = +1
Query: 52 VHLSEATTGG-GKASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAG 228
+ L E T G A + G + LGLGT++ F + EV +E+ + A E+G
Sbjct: 66 ISLQETTRAETGMAYRNLGKSGLRVSCLGLGTWVTFGGQISDEV----AERLMTIAYESG 121
Query: 229 YRLIDTAALYL---NEDQIGAAVRASGIPREDIFIVTKLPMD---------NQRDVVKQL 372
L DTA +Y E +G+ ++ G R + I TKL +++ +++ L
Sbjct: 122 VNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGL 181
Query: 373 EKSLARLNMSYVDLYLIHNPVAFNP 447
+ SL RL + YVD+ + P + P
Sbjct: 182 KGSLQRLQLEYVDVVFANRPDSNTP 206
>L39833-1|AAC37573.1| 408|Homo sapiens K+ channel beta-subunit
protein.
Length = 408
Score = 46.4 bits (105), Expect = 1e-04
Identities = 41/145 (28%), Positives = 68/145 (46%), Gaps = 13/145 (8%)
Frame = +1
Query: 52 VHLSEATTGG-GKASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAG 228
+ L E T G A + G + LGLGT++ F + EV +E+ + A E+G
Sbjct: 66 ISLQETTRAETGMAYRNLGKSGLRVSCLGLGTWVTFGGQISDEV----AERLMTIAYESG 121
Query: 229 YRLIDTAALYL---NEDQIGAAVRASGIPREDIFIVTKLPMD---------NQRDVVKQL 372
L DTA +Y E +G+ ++ G R + I TKL +++ +++ L
Sbjct: 122 VNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGL 181
Query: 373 EKSLARLNMSYVDLYLIHNPVAFNP 447
+ SL RL + YVD+ + P + P
Sbjct: 182 KGSLQRLQLEYVDVVFANRPDSNTP 206
>X83127-1|CAA58208.1| 401|Homo sapiens voltage gated potassium
channels, beta subunit protein.
Length = 401
Score = 45.6 bits (103), Expect = 2e-04
Identities = 36/124 (29%), Positives = 61/124 (49%), Gaps = 12/124 (9%)
Frame = +1
Query: 112 GNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYL---NEDQIGA 282
G + LGLGT++ F + EV +E+ + A E+G L DTA +Y E +G+
Sbjct: 80 GLRVSCLGLGTWVTFGGQISDEV----AERLMTIAYESGVNLFDTAEVYAAGKAEVILGS 135
Query: 283 AVRASGIPREDIFIVTKLPMD---------NQRDVVKQLEKSLARLNMSYVDLYLIHNPV 435
++ G R + I TKL +++ +++ L+ SL RL + YVD+ + P
Sbjct: 136 IIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPD 195
Query: 436 AFNP 447
+ P
Sbjct: 196 SNTP 199
>U33428-1|AAC50953.1| 401|Homo sapiens K+ channel beta 1a subunit
protein.
Length = 401
Score = 45.6 bits (103), Expect = 2e-04
Identities = 36/124 (29%), Positives = 61/124 (49%), Gaps = 12/124 (9%)
Frame = +1
Query: 112 GNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYL---NEDQIGA 282
G + LGLGT++ F + EV +E+ + A E+G L DTA +Y E +G+
Sbjct: 80 GLRVSCLGLGTWVTFGGQISDEV----AERLMTIAYESGVNLFDTAEVYAAGKAEVILGS 135
Query: 283 AVRASGIPREDIFIVTKLPMD---------NQRDVVKQLEKSLARLNMSYVDLYLIHNPV 435
++ G R + I TKL +++ +++ L+ SL RL + YVD+ + P
Sbjct: 136 IIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPD 195
Query: 436 AFNP 447
+ P
Sbjct: 196 SNTP 199
>L47665-1|AAC41926.1| 419|Homo sapiens K+ channel beta-subunit
protein.
Length = 419
Score = 45.6 bits (103), Expect = 2e-04
Identities = 36/124 (29%), Positives = 61/124 (49%), Gaps = 12/124 (9%)
Frame = +1
Query: 112 GNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYL---NEDQIGA 282
G + LGLGT++ F + EV +E+ + A E+G L DTA +Y E +G+
Sbjct: 98 GLRVSCLGLGTWVTFGGQISDEV----AERLMTIAYESGVNLFDTAEVYAAGKAEVILGS 153
Query: 283 AVRASGIPREDIFIVTKLPMD---------NQRDVVKQLEKSLARLNMSYVDLYLIHNPV 435
++ G R + I TKL +++ +++ L+ SL RL + YVD+ + P
Sbjct: 154 IIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPD 213
Query: 436 AFNP 447
+ P
Sbjct: 214 SNTP 217
>BC043166-1|AAH43166.1| 401|Homo sapiens potassium voltage-gated
channel, shaker-related subfamily, beta member 1
protein.
Length = 401
Score = 45.6 bits (103), Expect = 2e-04
Identities = 36/124 (29%), Positives = 61/124 (49%), Gaps = 12/124 (9%)
Frame = +1
Query: 112 GNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYL---NEDQIGA 282
G + LGLGT++ F + EV +E+ + A E+G L DTA +Y E +G+
Sbjct: 80 GLRVSCLGLGTWVTFGGQISDEV----AERLMTIAYESGVNLFDTAEVYAAGKAEVILGS 135
Query: 283 AVRASGIPREDIFIVTKLPMD---------NQRDVVKQLEKSLARLNMSYVDLYLIHNPV 435
++ G R + I TKL +++ +++ L+ SL RL + YVD+ + P
Sbjct: 136 IIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPD 195
Query: 436 AFNP 447
+ P
Sbjct: 196 SNTP 199
>AF026947-1|AAC52104.1| 330|Homo sapiens aflatoxin aldehyde
reductase AFAR protein.
Length = 330
Score = 40.7 bits (91), Expect = 0.005
Identities = 56/204 (27%), Positives = 85/204 (41%), Gaps = 14/204 (6%)
Frame = +1
Query: 124 PALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN---EDQIGAAVRA 294
P + + LG E G++ P S V+ LE G+ +DTA +Y + E +G
Sbjct: 5 PPPRVASVLGTMEMGRRMDAPA-SAAAVRAFLERGHTELDTAFMYSDGQSETILGGLGLG 63
Query: 295 SGIPREDIFIVTKL-PMDNQR----DVVKQLEKSLARLNMSYVDLYLIHNPVAFNPGFKG 459
G + I TK P D + V QLE SL RL VDL+ +H P P
Sbjct: 64 LGGGDCRVKIATKANPWDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHTPDHGTP---- 119
Query: 460 FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL----ENGQIKPSVLQVEVNLH 627
V+ +T + G +G+SN+ + ++ I NG I P+V Q N
Sbjct: 120 ---VE--ETLHACQRLHQEGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQGMYNAT 174
Query: 628 LGQ--DKLIDYCKRNGIVVMAFSP 693
Q +L + G+ A++P
Sbjct: 175 TRQVETELFPCLRHFGLRFYAYNP 198
>Y16675-1|CAA76347.1| 330|Homo sapiens aflatoxin B1-aldehyde
reductase protein.
Length = 330
Score = 39.9 bits (89), Expect = 0.009
Identities = 56/204 (27%), Positives = 85/204 (41%), Gaps = 14/204 (6%)
Frame = +1
Query: 124 PALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN---EDQIGAAVRA 294
P + + LG E G++ P S V+ LE G+ +DTA +Y + E +G
Sbjct: 5 PPPRVASVLGTMEMGRRMDAPA-SAAAVRAFLERGHTELDTAFMYSDGQSETILGGLGLG 63
Query: 295 SGIPREDIFIVTKL-PMDNQR----DVVKQLEKSLARLNMSYVDLYLIHNPVAFNPGFKG 459
G + I TK P D + V QLE SL RL VDL+ +H P P
Sbjct: 64 LGGGDCRVKIATKANPWDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHAPDHGTP---- 119
Query: 460 FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL----ENGQIKPSVLQVEVNLH 627
V+ +T + G +G+SN+ + ++ I NG I P+V Q N
Sbjct: 120 ---VE--ETLHACQRLHQEGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQGMYNAT 174
Query: 628 LGQ--DKLIDYCKRNGIVVMAFSP 693
Q +L + G+ A++P
Sbjct: 175 TRQVETELFPCLRHFGLRFYAYNP 198
>BT007347-1|AAP36011.1| 330|Homo sapiens aldo-keto reductase family
7, member A2 (aflatoxin aldehyde reductase) protein.
Length = 330
Score = 39.9 bits (89), Expect = 0.009
Identities = 56/204 (27%), Positives = 85/204 (41%), Gaps = 14/204 (6%)
Frame = +1
Query: 124 PALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN---EDQIGAAVRA 294
P + + LG E G++ P S V+ LE G+ +DTA +Y + E +G
Sbjct: 5 PPPRVASVLGTMEMGRRMDAPA-SAAAVRAFLERGHTELDTAFMYSDGQSETILGGLGLG 63
Query: 295 SGIPREDIFIVTKL-PMDNQR----DVVKQLEKSLARLNMSYVDLYLIHNPVAFNPGFKG 459
G + I TK P D + V QLE SL RL VDL+ +H P P
Sbjct: 64 LGGGDCRVKIATKANPWDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHAPDHGTP---- 119
Query: 460 FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL----ENGQIKPSVLQVEVNLH 627
V+ +T + G +G+SN+ + ++ I NG I P+V Q N
Sbjct: 120 ---VE--ETLHACQRLHQEGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQGMYNAT 174
Query: 628 LGQ--DKLIDYCKRNGIVVMAFSP 693
Q +L + G+ A++P
Sbjct: 175 TRQVETELFPCLRHFGLRFYAYNP 198
>BC013996-1|AAH13996.1| 330|Homo sapiens AKR7A2 protein protein.
Length = 330
Score = 39.9 bits (89), Expect = 0.009
Identities = 56/204 (27%), Positives = 85/204 (41%), Gaps = 14/204 (6%)
Frame = +1
Query: 124 PALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN---EDQIGAAVRA 294
P + + LG E G++ P S V+ LE G+ +DTA +Y + E +G
Sbjct: 5 PPPRVASVLGTMEMGRRMDAPA-SAAAVRAFLERGHTELDTAFMYSDGQSETILGGLGLG 63
Query: 295 SGIPREDIFIVTKL-PMDNQR----DVVKQLEKSLARLNMSYVDLYLIHNPVAFNPGFKG 459
G + I TK P D + V QLE SL RL VDL+ +H P P
Sbjct: 64 LGGGDCRVKIATKANPWDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHAPDHGTP---- 119
Query: 460 FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL----ENGQIKPSVLQVEVNLH 627
V+ +T + G +G+SN+ + ++ I NG I P+V Q N
Sbjct: 120 ---VE--ETLHACQRLHQEGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQGMYNAT 174
Query: 628 LGQ--DKLIDYCKRNGIVVMAFSP 693
Q +L + G+ A++P
Sbjct: 175 TRQVETELFPCLRHFGLRFYAYNP 198
>BC012171-1|AAH12171.1| 330|Homo sapiens AKR7A2 protein protein.
Length = 330
Score = 39.9 bits (89), Expect = 0.009
Identities = 56/204 (27%), Positives = 85/204 (41%), Gaps = 14/204 (6%)
Frame = +1
Query: 124 PALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN---EDQIGAAVRA 294
P + + LG E G++ P S V+ LE G+ +DTA +Y + E +G
Sbjct: 5 PPPRVASVLGTMEMGRRMDAPA-SAAAVRAFLERGHTELDTAFMYSDGQSETILGGLGLG 63
Query: 295 SGIPREDIFIVTKL-PMDNQR----DVVKQLEKSLARLNMSYVDLYLIHNPVAFNPGFKG 459
G + I TK P D + V QLE SL RL VDL+ +H P P
Sbjct: 64 LGGGDCRVKIATKANPWDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHAPDHGTP---- 119
Query: 460 FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL----ENGQIKPSVLQVEVNLH 627
V+ +T + G +G+SN+ + ++ I NG I P+V Q N
Sbjct: 120 ---VE--ETLHACQRLHQEGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQGMYNAT 174
Query: 628 LGQ--DKLIDYCKRNGIVVMAFSP 693
Q +L + G+ A++P
Sbjct: 175 TRQVETELFPCLRHFGLRFYAYNP 198
>BC011586-1|AAH11586.1| 330|Homo sapiens AKR7A2 protein protein.
Length = 330
Score = 39.9 bits (89), Expect = 0.009
Identities = 56/204 (27%), Positives = 85/204 (41%), Gaps = 14/204 (6%)
Frame = +1
Query: 124 PALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN---EDQIGAAVRA 294
P + + LG E G++ P S V+ LE G+ +DTA +Y + E +G
Sbjct: 5 PPPRVASVLGTMEMGRRMDAPA-SAAAVRAFLERGHTELDTAFMYSDGQSETILGGLGLG 63
Query: 295 SGIPREDIFIVTKL-PMDNQR----DVVKQLEKSLARLNMSYVDLYLIHNPVAFNPGFKG 459
G + I TK P D + V QLE SL RL VDL+ +H P P
Sbjct: 64 LGGGDCRVKIATKANPWDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHAPDHGTP---- 119
Query: 460 FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL----ENGQIKPSVLQVEVNLH 627
V+ +T + G +G+SN+ + ++ I NG I P+V Q N
Sbjct: 120 ---VE--ETLHACQRLHQEGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQGMYNAT 174
Query: 628 LGQ--DKLIDYCKRNGIVVMAFSP 693
Q +L + G+ A++P
Sbjct: 175 TRQVETELFPCLRHFGLRFYAYNP 198
>BC010852-1|AAH10852.1| 330|Homo sapiens AKR7A2 protein protein.
Length = 330
Score = 39.9 bits (89), Expect = 0.009
Identities = 56/204 (27%), Positives = 85/204 (41%), Gaps = 14/204 (6%)
Frame = +1
Query: 124 PALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN---EDQIGAAVRA 294
P + + LG E G++ P S V+ LE G+ +DTA +Y + E +G
Sbjct: 5 PPPRVASVLGTMEMGRRMDAPA-SAAAVRAFLERGHTELDTAFMYSDGQSETILGGLGLG 63
Query: 295 SGIPREDIFIVTKL-PMDNQR----DVVKQLEKSLARLNMSYVDLYLIHNPVAFNPGFKG 459
G + I TK P D + V QLE SL RL VDL+ +H P P
Sbjct: 64 LGGGDCRVKIATKANPWDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHAPDHGTP---- 119
Query: 460 FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL----ENGQIKPSVLQVEVNLH 627
V+ +T + G +G+SN+ + ++ I NG I P+V Q N
Sbjct: 120 ---VE--ETLHACQRLHQEGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQGMYNAT 174
Query: 628 LGQ--DKLIDYCKRNGIVVMAFSP 693
Q +L + G+ A++P
Sbjct: 175 TRQVETELFPCLRHFGLRFYAYNP 198
>BC007352-1|AAH07352.2| 358|Homo sapiens AKR7A2 protein protein.
Length = 358
Score = 39.9 bits (89), Expect = 0.009
Identities = 56/204 (27%), Positives = 85/204 (41%), Gaps = 14/204 (6%)
Frame = +1
Query: 124 PALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN---EDQIGAAVRA 294
P + + LG E G++ P S V+ LE G+ +DTA +Y + E +G
Sbjct: 33 PPPRVASVLGTMEMGRRMDAPA-SAAAVRAFLERGHTELDTAFMYSDGQSETILGGLGLG 91
Query: 295 SGIPREDIFIVTKL-PMDNQR----DVVKQLEKSLARLNMSYVDLYLIHNPVAFNPGFKG 459
G + I TK P D + V QLE SL RL VDL+ +H P P
Sbjct: 92 LGGGDCRVKIATKANPWDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHAPDHGTP---- 147
Query: 460 FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL----ENGQIKPSVLQVEVNLH 627
V+ +T + G +G+SN+ + ++ I NG I P+V Q N
Sbjct: 148 ---VE--ETLHACQRLHQEGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQGMYNAT 202
Query: 628 LGQ--DKLIDYCKRNGIVVMAFSP 693
Q +L + G+ A++P
Sbjct: 203 TRQVETELFPCLRHFGLRFYAYNP 226
>BC004111-1|AAH04111.3| 330|Homo sapiens AKR7A2 protein protein.
Length = 330
Score = 39.9 bits (89), Expect = 0.009
Identities = 56/204 (27%), Positives = 85/204 (41%), Gaps = 14/204 (6%)
Frame = +1
Query: 124 PALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN---EDQIGAAVRA 294
P + + LG E G++ P S V+ LE G+ +DTA +Y + E +G
Sbjct: 5 PPPRVASVLGTMEMGRRMDAPA-SAAAVRAFLERGHTELDTAFMYSDGQSETILGGLGLG 63
Query: 295 SGIPREDIFIVTKL-PMDNQR----DVVKQLEKSLARLNMSYVDLYLIHNPVAFNPGFKG 459
G + I TK P D + V QLE SL RL VDL+ +H P P
Sbjct: 64 LGGGDCRVKIATKANPWDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHAPDHGTP---- 119
Query: 460 FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL----ENGQIKPSVLQVEVNLH 627
V+ +T + G +G+SN+ + ++ I NG I P+V Q N
Sbjct: 120 ---VE--ETLHACQRLHQEGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQGMYNAT 174
Query: 628 LGQ--DKLIDYCKRNGIVVMAFSP 693
Q +L + G+ A++P
Sbjct: 175 TRQVETELFPCLRHFGLRFYAYNP 198
>AL035413-8|CAB72321.1| 330|Homo sapiens aldo-keto reductase family
7, member A2 (aflatoxin aldehyde reductase) protein.
Length = 330
Score = 39.9 bits (89), Expect = 0.009
Identities = 56/204 (27%), Positives = 85/204 (41%), Gaps = 14/204 (6%)
Frame = +1
Query: 124 PALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN---EDQIGAAVRA 294
P + + LG E G++ P S V+ LE G+ +DTA +Y + E +G
Sbjct: 5 PPPRVASVLGTMEMGRRMDAPA-SAAAVRAFLERGHTELDTAFMYSDGQSETILGGLGLG 63
Query: 295 SGIPREDIFIVTKL-PMDNQR----DVVKQLEKSLARLNMSYVDLYLIHNPVAFNPGFKG 459
G + I TK P D + V QLE SL RL VDL+ +H P P
Sbjct: 64 LGGGDCRVKIATKANPWDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHAPDHGTP---- 119
Query: 460 FDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL----ENGQIKPSVLQVEVNLH 627
V+ +T + G +G+SN+ + ++ I NG I P+V Q N
Sbjct: 120 ---VE--ETLHACQRLHQEGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQGMYNAT 174
Query: 628 LGQ--DKLIDYCKRNGIVVMAFSP 693
Q +L + G+ A++P
Sbjct: 175 TRQVETELFPCLRHFGLRFYAYNP 198
>AB037905-2|BAA92890.1| 45|Homo sapiens truncated aldo-keto
reductase protein.
Length = 45
Score = 38.7 bits (86), Expect = 0.022
Identities = 17/31 (54%), Positives = 21/31 (67%)
Frame = +1
Query: 358 VVKQLEKSLARLNMSYVDLYLIHNPVAFNPG 450
V + LE SL +L +SY+DLYL H PV PG
Sbjct: 11 VQRGLEMSLKKLQLSYMDLYLFHFPVPLQPG 41
>BC042420-1|AAH42420.2| 331|Homo sapiens aldo-keto reductase family
7, member A3 (aflatoxin aldehyde reductase) protein.
Length = 331
Score = 36.7 bits (81), Expect = 0.087
Identities = 56/198 (28%), Positives = 84/198 (42%), Gaps = 14/198 (7%)
Frame = +1
Query: 142 TFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYL---NEDQIGAAVRASGIPRE 312
T LG E G++ P S + LE G+ IDTA +Y +E +G G
Sbjct: 12 TVLGAMEMGRRMDAP-TSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDC 70
Query: 313 DIFIVTK-LPMDNQR---DVVK-QLEKSLARLNMSYVDLYLIHNPVAFNPGFKGFDIVDY 477
+ I TK +P+ D ++ QLE SL RL VDL+ +H P P V+
Sbjct: 71 RVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTP-------VE- 122
Query: 478 LDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL----ENGQIKPSVLQVEVNLHLGQ--D 639
+T + + G +G+SN+ ++ I NG I P+V Q N Q
Sbjct: 123 -ETLRACHQLHQEGKFMELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVET 181
Query: 640 KLIDYCKRNGIVVMAFSP 693
+L + G+ AF+P
Sbjct: 182 ELFPCLRHFGLRFYAFNP 199
>BC031562-1|AAH31562.1| 331|Homo sapiens aldo-keto reductase family
7, member A3 (aflatoxin aldehyde reductase) protein.
Length = 331
Score = 36.7 bits (81), Expect = 0.087
Identities = 56/198 (28%), Positives = 84/198 (42%), Gaps = 14/198 (7%)
Frame = +1
Query: 142 TFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYL---NEDQIGAAVRASGIPRE 312
T LG E G++ P S + LE G+ IDTA +Y +E +G G
Sbjct: 12 TVLGAMEMGRRMDAP-TSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDC 70
Query: 313 DIFIVTK-LPMDNQR---DVVK-QLEKSLARLNMSYVDLYLIHNPVAFNPGFKGFDIVDY 477
+ I TK +P+ D ++ QLE SL RL VDL+ +H P P V+
Sbjct: 71 RVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTP-------VE- 122
Query: 478 LDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL----ENGQIKPSVLQVEVNLHLGQ--D 639
+T + + G +G+SN+ ++ I NG I P+V Q N Q
Sbjct: 123 -ETLRACHQLHQEGKFMELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVET 181
Query: 640 KLIDYCKRNGIVVMAFSP 693
+L + G+ AF+P
Sbjct: 182 ELFPCLRHFGLRFYAFNP 199
>AY780786-1|AAV98356.1| 372|Homo sapiens potassium voltage-gated
channel beta subunit protein.
Length = 372
Score = 36.7 bits (81), Expect = 0.087
Identities = 27/92 (29%), Positives = 45/92 (48%), Gaps = 3/92 (3%)
Frame = +1
Query: 112 GNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYL---NEDQIGA 282
G + LGLGT++ F + EV +E+ + A E+G L DTA +Y E +G+
Sbjct: 80 GLRVSCLGLGTWVTFGGQISDEV----AERLMTIAYESGVNLFDTAEVYAAGKAEVILGS 135
Query: 283 AVRASGIPREDIFIVTKLPMDNQRDVVKQLEK 378
++ G R + I TKL + + + L +
Sbjct: 136 IIKKKGWRRSSLVITTKLYWGGKAETERGLSR 167
>AJ271799-1|CAC81076.1| 331|Homo sapiens aflatoxin B1 aldehyde
reductase 2 protein.
Length = 331
Score = 36.7 bits (81), Expect = 0.087
Identities = 56/198 (28%), Positives = 84/198 (42%), Gaps = 14/198 (7%)
Frame = +1
Query: 142 TFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYL---NEDQIGAAVRASGIPRE 312
T LG E G++ P S + LE G+ IDTA +Y +E +G G
Sbjct: 12 TVLGAMEMGRRMDAP-TSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDC 70
Query: 313 DIFIVTK-LPMDNQR---DVVK-QLEKSLARLNMSYVDLYLIHNPVAFNPGFKGFDIVDY 477
+ I TK +P+ D ++ QLE SL RL VDL+ +H P P V+
Sbjct: 71 RVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTP-------VE- 122
Query: 478 LDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL----ENGQIKPSVLQVEVNLHLGQ--D 639
+T + + G +G+SN+ ++ I NG I P+V Q N Q
Sbjct: 123 -ETLRACHQLHQEGKFMELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVET 181
Query: 640 KLIDYCKRNGIVVMAFSP 693
+L + G+ AF+P
Sbjct: 182 ELFPCLRHFGLRFYAFNP 199
>AF040639-1|AAD02195.1| 331|Homo sapiens aflatoxin B1-aldehyde
reductase protein.
Length = 331
Score = 36.7 bits (81), Expect = 0.087
Identities = 56/198 (28%), Positives = 84/198 (42%), Gaps = 14/198 (7%)
Frame = +1
Query: 142 TFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN---EDQIGAAVRASGIPRE 312
T LG E G++ P S + LE G+ IDTA +Y + E +G G
Sbjct: 12 TVLGAMEMGRRMDAP-TSAAVTRAFLERGHTEIDTAFVYSDGQSETILGGLGLRLGGSDC 70
Query: 313 DIFIVTK-LPMDNQR---DVVK-QLEKSLARLNMSYVDLYLIHNPVAFNPGFKGFDIVDY 477
+ I TK +P+ D ++ QLE SL RL VDL+ +H P P V+
Sbjct: 71 RVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTP-------VE- 122
Query: 478 LDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL----ENGQIKPSVLQVEVNLHLGQ--D 639
+T + + G +G+SN+ ++ I NG I P+V Q N Q
Sbjct: 123 -ETLRACHQLHQEGKFMELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVET 181
Query: 640 KLIDYCKRNGIVVMAFSP 693
+L + G+ AF+P
Sbjct: 182 ELFPCLRHFGLRFYAFNP 199
>BC025709-1|AAH25709.1| 331|Homo sapiens aldo-keto reductase family
7, member A3 (aflatoxin aldehyde reductase) protein.
Length = 331
Score = 36.3 bits (80), Expect = 0.11
Identities = 56/198 (28%), Positives = 84/198 (42%), Gaps = 14/198 (7%)
Frame = +1
Query: 142 TFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYL---NEDQIGAAVRASGIPRE 312
T LG E G++ P S + LE G+ IDTA +Y +E +G G
Sbjct: 12 TVLGAMEMGRRMDAP-TSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDC 70
Query: 313 DIFIVTK-LPMDNQR---DVVK-QLEKSLARLNMSYVDLYLIHNPVAFNPGFKGFDIVDY 477
+ I TK +P+ D ++ QLE SL RL VDL+ +H P P V+
Sbjct: 71 RVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTP-------VE- 122
Query: 478 LDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL----ENGQIKPSVLQVEVNLHLGQ--D 639
+T + + G +G+SN+ ++ I NG I P+V Q N Q
Sbjct: 123 -ETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVET 181
Query: 640 KLIDYCKRNGIVVMAFSP 693
+L + G+ AF+P
Sbjct: 182 ELFPCLRHFGLRFYAFNP 199
>AL035413-11|CAI22232.1| 331|Homo sapiens aldo-keto reductase
family 7, member A3 (aflatoxin aldehyde reductase)
protein.
Length = 331
Score = 36.3 bits (80), Expect = 0.11
Identities = 56/198 (28%), Positives = 84/198 (42%), Gaps = 14/198 (7%)
Frame = +1
Query: 142 TFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYL---NEDQIGAAVRASGIPRE 312
T LG E G++ P S + LE G+ IDTA +Y +E +G G
Sbjct: 12 TVLGAMEMGRRMDAP-TSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDC 70
Query: 313 DIFIVTK-LPMDNQR---DVVK-QLEKSLARLNMSYVDLYLIHNPVAFNPGFKGFDIVDY 477
+ I TK +P+ D ++ QLE SL RL VDL+ +H P P V+
Sbjct: 71 RVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTP-------VE- 122
Query: 478 LDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL----ENGQIKPSVLQVEVNLHLGQ--D 639
+T + + G +G+SN+ ++ I NG I P+V Q N Q
Sbjct: 123 -ETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVET 181
Query: 640 KLIDYCKRNGIVVMAFSP 693
+L + G+ AF+P
Sbjct: 182 ELFPCLRHFGLRFYAFNP 199
>AJ278012-1|CAC79668.1| 259|Homo sapiens aflatoxin B1 aldehyde
reductase 3 protein.
Length = 259
Score = 33.5 bits (73), Expect = 0.81
Identities = 32/118 (27%), Positives = 50/118 (42%), Gaps = 6/118 (5%)
Frame = +1
Query: 358 VVKQLEKSLARLNMSYVDLYLIHNPVAFNPGFKGFDIVDYLDTWKGMEEAKNLGLAKSIG 537
V QLE SL RL VDL+ +H P P V+ +T + + G +G
Sbjct: 19 VRSQLETSLKRLQCPUVDLFYLHAPDHSAP-------VE--ETLRACHQLHQEGKFVELG 69
Query: 538 ISNFNTTQIDRIL----ENGQIKPSVLQ--VEVNLHLGQDKLIDYCKRNGIVVMAFSP 693
+SN+ ++ I NG I P+V Q + +L Y + G+ A++P
Sbjct: 70 LSNYAAWEVAEICTLCKSNGWILPTVYQGMYSATTRQVETELFPYLRHFGLRFYAYNP 127
>Y13790-1|CAA74116.1| 123|Homo sapiens immunoglobulin heavy chain
variable and joining regions protein.
Length = 123
Score = 32.7 bits (71), Expect = 1.4
Identities = 23/90 (25%), Positives = 36/90 (40%), Gaps = 4/90 (4%)
Frame = +1
Query: 457 GFDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQID----RILENGQIKPSVLQVEVNL 624
GF DY +W K LGL I S T D R + + + L +++N
Sbjct: 26 GFTFSDYYMSWIRQAPGKGLGLISYITSSGHITYYADSVEGRFIISRDNAKNSLYLQMNT 85
Query: 625 HLGQDKLIDYCKRNGIVVMAFSPFGPMFHD 714
+D + YC R G+ + F +H+
Sbjct: 86 LRAEDTAVYYCARVGLAGGTYFQFWSGYHE 115
>BX537840-1|CAD97851.1| 2150|Homo sapiens hypothetical protein
protein.
Length = 2150
Score = 32.3 bits (70), Expect = 1.9
Identities = 27/89 (30%), Positives = 40/89 (44%), Gaps = 1/89 (1%)
Frame = +1
Query: 238 IDTAALYLNEDQIGAAVRASGIPREDI-FIVTKLPMDNQRDVVKQLEKSLARLNMSYVDL 414
IDT L + DQ V +E I FI L N V++L++++ M +V
Sbjct: 1070 IDT--LLVATDQTERIVEPPENIQEKIAFIFNNLSQSNMTQKVEELKETVKEEFMPWVSQ 1127
Query: 415 YLIHNPVAFNPGFKGFDIVDYLDTWKGME 501
YL+ V+ P F ++LDT K E
Sbjct: 1128 YLVMKRVSIEPNFHSL-YSNFLDTLKNPE 1155
>BC040523-1|AAH40523.1| 1551|Homo sapiens CCR4-NOT transcription
complex, subunit 1 protein.
Length = 1551
Score = 32.3 bits (70), Expect = 1.9
Identities = 27/89 (30%), Positives = 40/89 (44%), Gaps = 1/89 (1%)
Frame = +1
Query: 238 IDTAALYLNEDQIGAAVRASGIPREDI-FIVTKLPMDNQRDVVKQLEKSLARLNMSYVDL 414
IDT L + DQ V +E I FI L N V++L++++ M +V
Sbjct: 1075 IDT--LLVATDQTERIVEPPENIQEKIAFIFNNLSQSNMTQKVEELKETVKEEFMPWVSQ 1132
Query: 415 YLIHNPVAFNPGFKGFDIVDYLDTWKGME 501
YL+ V+ P F ++LDT K E
Sbjct: 1133 YLVMKRVSIEPNFHSL-YSNFLDTLKNPE 1160
>BC024317-1|AAH24317.1| 1620|Homo sapiens CNOT1 protein protein.
Length = 1620
Score = 32.3 bits (70), Expect = 1.9
Identities = 27/89 (30%), Positives = 40/89 (44%), Gaps = 1/89 (1%)
Frame = +1
Query: 238 IDTAALYLNEDQIGAAVRASGIPREDI-FIVTKLPMDNQRDVVKQLEKSLARLNMSYVDL 414
IDT L + DQ V +E I FI L N V++L++++ M +V
Sbjct: 319 IDT--LLVATDQTERIVEPPENIQEKIAFIFNNLSQSNMTQKVEELKETVKEEFMPWVSQ 376
Query: 415 YLIHNPVAFNPGFKGFDIVDYLDTWKGME 501
YL+ V+ P F ++LDT K E
Sbjct: 377 YLVMKRVSIEPNFHSL-YSNFLDTLKNPE 404
>AB067375-1|BAC02410.1| 121|Homo sapiens immunoglobulin heavy chain
VHDJ region protein.
Length = 121
Score = 32.3 bits (70), Expect = 1.9
Identities = 20/94 (21%), Positives = 40/94 (42%), Gaps = 3/94 (3%)
Frame = +1
Query: 457 GFDIVDYLDTWKGMEEAKNL---GLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLH 627
G + +Y +W K L G GI+N+N + + R+ + + +++N
Sbjct: 26 GGSLTNYYWSWIRQPPGKGLQWIGYISHSGITNYNPSLMSRLTMSVDTPKNQFSLKLNSV 85
Query: 628 LGQDKLIDYCKRNGIVVMAFSPFGPMFHDSLPSI 729
D + YC R G++ + F P +L ++
Sbjct: 86 TTADTGVYYCAREGVLPASIRLFDPWGQGTLVTV 119
>AB063668-1|BAC01296.1| 119|Homo sapiens immunoglobulin heavy chain
VHDJ region protein.
Length = 119
Score = 32.3 bits (70), Expect = 1.9
Identities = 22/85 (25%), Positives = 34/85 (40%), Gaps = 4/85 (4%)
Frame = +1
Query: 457 GFDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIK----PSVLQVEVNL 624
GF DY +W K L I S+ T D + I + L +++N
Sbjct: 26 GFTFSDYYMSWIRQAPGKGLEWVSYISSSSSYTNYADSVKGRFTISRDNAKNSLYLQMNS 85
Query: 625 HLGQDKLIDYCKRNGIVVMAFSPFG 699
+D + YC R+G+ AF +G
Sbjct: 86 LRAEDTAVYYCARDGVATDAFDIWG 110
>AB023224-1|BAA76851.2| 1835|Homo sapiens KIAA1007 protein protein.
Length = 1835
Score = 32.3 bits (70), Expect = 1.9
Identities = 27/89 (30%), Positives = 40/89 (44%), Gaps = 1/89 (1%)
Frame = +1
Query: 238 IDTAALYLNEDQIGAAVRASGIPREDI-FIVTKLPMDNQRDVVKQLEKSLARLNMSYVDL 414
IDT L + DQ V +E I FI L N V++L++++ M +V
Sbjct: 534 IDT--LLVATDQTERIVEPPENIQEKIAFIFNNLSQSNMTQKVEELKETVKEEFMPWVSQ 591
Query: 415 YLIHNPVAFNPGFKGFDIVDYLDTWKGME 501
YL+ V+ P F ++LDT K E
Sbjct: 592 YLVMKRVSIEPNFHSL-YSNFLDTLKNPE 619
>AM079206-1|CAL03352.1| 101|Homo sapiens immunoglobulin heavy chain
variable region protein.
Length = 101
Score = 31.9 bits (69), Expect = 2.5
Identities = 21/73 (28%), Positives = 30/73 (41%), Gaps = 4/73 (5%)
Frame = +1
Query: 457 GFDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQID----RILENGQIKPSVLQVEVNL 624
GF + Y TW K L SIGI N T D R + I S L ++++
Sbjct: 29 GFTLSSYAMTWVRQAPGKGLEWVSSIGIRNSGTYYADSVKGRFAISRDISRSTLYLQMDS 88
Query: 625 HLGQDKLIDYCKR 663
+D + YC +
Sbjct: 89 LRAEDTALYYCAK 101
>DQ926255-1|ABK81474.1| 122|Homo sapiens immunoglobulin heavy chain
variable region protein.
Length = 122
Score = 30.7 bits (66), Expect = 5.7
Identities = 22/85 (25%), Positives = 32/85 (37%), Gaps = 4/85 (4%)
Frame = +1
Query: 457 GFDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIK----PSVLQVEVNL 624
GF DY +W K L I S+ T D + I + L +++N
Sbjct: 26 GFTFSDYYMSWIRQAPGKGLEWVSYISGSSSYTNYADSVKGRFTISRDNAKNSLYLQMNS 85
Query: 625 HLGQDKLIDYCKRNGIVVMAFSPFG 699
+D + YC R V F P+G
Sbjct: 86 LRAEDTAVYYCARGMFTVTPFGPWG 110
>AJ555274-1|CAD87759.1| 118|Homo sapiens immunoglobulin heavy chain
variable region protein.
Length = 118
Score = 30.3 bits (65), Expect = 7.5
Identities = 23/85 (27%), Positives = 34/85 (40%), Gaps = 4/85 (4%)
Frame = +1
Query: 457 GFDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQID----RILENGQIKPSVLQVEVNL 624
GF DY TW K L +I T +D R + + L +++N
Sbjct: 26 GFFFSDYWMTWVRQAPDKGLEWVANINQHETETNYVDSVKGRFAMSRDNTKNALYLQMNS 85
Query: 625 HLGQDKLIDYCKRNGIVVMAFSPFG 699
+D + YC R IV + F P+G
Sbjct: 86 LSAEDTAVYYCAR--IVSVGFDPWG 108
>AF471315-1|AAQ05490.1| 128|Homo sapiens Ig heavy chain variable
region, VH3 family protein.
Length = 128
Score = 30.3 bits (65), Expect = 7.5
Identities = 21/74 (28%), Positives = 30/74 (40%), Gaps = 4/74 (5%)
Frame = +1
Query: 457 GFDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHL-- 630
GF DY+ +W K L SI S NT D + I + V+L +
Sbjct: 26 GFTFDDYVMSWVRQAPGKELEWVASISGSAVNTYYADSVKGRFSISRDSFKNTVHLQMNG 85
Query: 631 --GQDKLIDYCKRN 666
G+D + YC R+
Sbjct: 86 LRGEDTALYYCARD 99
>U17968-1|AAC50113.1| 133|Homo sapiens voltage-gated potassium
channel beta subunit protein.
Length = 133
Score = 29.9 bits (64), Expect = 10.0
Identities = 23/70 (32%), Positives = 34/70 (48%), Gaps = 1/70 (1%)
Frame = +1
Query: 52 VHLSEATTGG-GKASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAG 228
+ L E T G A + G + LGLGT++ F + EV +E+ + A E+G
Sbjct: 63 ISLQETTRAETGMAYRNLGKSGLRVSCLGLGTWVTFGGQISDEV----AERLMTIAYESG 118
Query: 229 YRLIDTAALY 258
L DTA +Y
Sbjct: 119 VNLFDTAEVY 128
>AM082400-1|CAL06546.1| 101|Homo sapiens immunoglobulin heavy chain
variable region protein.
Length = 101
Score = 29.9 bits (64), Expect = 10.0
Identities = 20/73 (27%), Positives = 29/73 (39%), Gaps = 4/73 (5%)
Frame = +1
Query: 457 GFDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQID----RILENGQIKPSVLQVEVNL 624
GF + Y TW K L SI I+ NT D R + + L +++N
Sbjct: 29 GFSLSSYAMTWVRQAPGKGLEWVSSISITGANTYFADSVKGRFTVSRDSSKNTLYLQMNS 88
Query: 625 HLGQDKLIDYCKR 663
+D I YC +
Sbjct: 89 LRAEDTAIYYCAK 101
>AM079381-1|CAL03527.1| 100|Homo sapiens immunoglobulin heavy chain
variable region protein.
Length = 100
Score = 29.9 bits (64), Expect = 10.0
Identities = 19/71 (26%), Positives = 29/71 (40%), Gaps = 4/71 (5%)
Frame = +1
Query: 457 GFDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQID----RILENGQIKPSVLQVEVNL 624
GF +Y TW K L ++G + FNT D R + + L +E+N
Sbjct: 29 GFSFSNYAMTWVRQAPGKGLEWVSAVGSTGFNTFYADSVKGRFIISRDNFRDTLFLEMNS 88
Query: 625 HLGQDKLIDYC 657
+D + YC
Sbjct: 89 LRAEDTAVYYC 99
>AB066933-1|BAC01971.1| 129|Homo sapiens immunoglobulin heavy chain
VHDJ region protein.
Length = 129
Score = 29.9 bits (64), Expect = 10.0
Identities = 22/79 (27%), Positives = 32/79 (40%), Gaps = 4/79 (5%)
Frame = +1
Query: 457 GFDIVDYLDTWKGMEEAKNLGLAKSIGISNFNTT--QI--DRILENGQIKPSVLQVEVNL 624
G+ Y W + L +I S TT QI R+ G S + +E++
Sbjct: 26 GYSFTTYYIHWVRQAPGQGLEWMGTINPSGDTTTYAQIFQGRVTMTGDTSTSTVYMELSS 85
Query: 625 HLGQDKLIDYCKRNGIVVM 681
+D + YC R IVVM
Sbjct: 86 LRSEDTAVYYCAREAIVVM 104
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 110,598,921
Number of Sequences: 237096
Number of extensions: 2270529
Number of successful extensions: 10155
Number of sequences better than 10.0: 132
Number of HSP's better than 10.0 without gapping: 9610
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 9818
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8791154398
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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